Guide to the Human Genome
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Search of human proteins with 153792764

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153792764 hypothetical protein LOC57624 [Homo sapiens]
         (653 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153792764 hypothetical protein LOC57624 [Homo sapiens]            1327   0.0  
gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]         1241   0.0  
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                   357   2e-98
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]              209   6e-54
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         63   1e-09
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                62   2e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   5e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    57   5e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    57   5e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    57   5e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         57   7e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    56   9e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   2e-07
gi|55750053 atrophin-1 [Homo sapiens]                                  53   8e-07
gi|55750041 atrophin-1 [Homo sapiens]                                  53   8e-07
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 53   1e-06
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 53   1e-06
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  53   1e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is...    53   1e-06
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    53   1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        52   2e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  52   2e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    51   3e-06
gi|151301154 mucin 6, gastric [Homo sapiens]                           51   3e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              51   4e-06
gi|146134388 YLP motif containing 1 [Homo sapiens]                     51   4e-06
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         50   5e-06
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           50   5e-06
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    49   1e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   49   2e-05

>gi|153792764 hypothetical protein LOC57624 [Homo sapiens]
          Length = 653

 Score = 1327 bits (3434), Expect = 0.0
 Identities = 653/653 (100%), Positives = 653/653 (100%)

Query: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60
           MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE
Sbjct: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60

Query: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120
           KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS
Sbjct: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120

Query: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180
           LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR
Sbjct: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180

Query: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240
           PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE
Sbjct: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240

Query: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300
           EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT
Sbjct: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300

Query: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
           VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV
Sbjct: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420
           TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL
Sbjct: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420

Query: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480
           YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV
Sbjct: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480

Query: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
           SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK
Sbjct: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540

Query: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSP 600
           STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSP
Sbjct: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSP 600

Query: 601 TLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVPSSLANRD 653
           TLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVPSSLANRD
Sbjct: 601 TLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVPSSLANRD 653


>gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]
          Length = 669

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 617/652 (94%), Positives = 624/652 (95%), Gaps = 10/652 (1%)

Query: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60
           MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE
Sbjct: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60

Query: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120
           KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS
Sbjct: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120

Query: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180
           LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR
Sbjct: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180

Query: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240
           PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE
Sbjct: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240

Query: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300
           EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT
Sbjct: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300

Query: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
           VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV
Sbjct: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420
           TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL
Sbjct: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420

Query: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480
           YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV
Sbjct: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480

Query: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
           SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK
Sbjct: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540

Query: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSP 600
           STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPG PVVTSRLGRCSVSP
Sbjct: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRLGRCSVSP 600

Query: 601 TLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSD-----LQQSQVPS 647
           TLLAGNHSS+  +    G      G+   S    + S D     LQ +Q+P+
Sbjct: 601 TLLAGNHSSDLVLERNSG-----GGLDHESAWGSQDSQDVFQGALQDTQLPT 647


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score =  357 bits (916), Expect = 2e-98
 Identities = 252/595 (42%), Positives = 324/595 (54%), Gaps = 71/595 (11%)

Query: 12   EEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKEKNEKRRRQEEA 71
            E   +++FLQ  EDMG+K YD LVIQNASDIARENDRLR+E N  Y KEK E R  QEE 
Sbjct: 1177 EVTSINSFLQNTEDMGLKTYDALVIQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEG 1236

Query: 72   IKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDS 131
             KR   + G         +HF    M++ A  D L   C  G S+ S SLHSV   DD S
Sbjct: 1237 SKRTDDKSGP--------RHFHPSSMSVCAAVDGLGQ-CLVGPSIWSPSLHSVFSMDDSS 1287

Query: 132  SCGS-RRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYS--K 188
            S  S R+QPPPKPKRDP+T+LS S E VS   A  S       EA A+PRPHSD+YS  K
Sbjct: 1288 SLPSPRKQPPPKPKRDPNTRLSASYEAVS---ACLSAAREAANEALARPRPHSDDYSTMK 1344

Query: 189  KIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQM-----------GSPAGD 237
            KIPP KPKR+PNT+LS S++E    + G  R +    ++   +            +P GD
Sbjct: 1345 KIPPRKPKRSPNTKLSGSYEEISGSRPGDARPAGAPGAAARVLTPGTPQCALPPAAPPGD 1404

Query: 238  PEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCA 297
             ++ EPVYIEM+G+  R    +  D  E+VYEEMK  + DD G  A     H       A
Sbjct: 1405 EDDSEPVYIEMLGHAARP---DSPDPGESVYEEMKCCLPDDGGPGAGSFLLHG------A 1455

Query: 298  TPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTP 357
            +P  P L  A       P G  CDIPPPFPNLL HRPPLLVFPP PV CSP SDESPLTP
Sbjct: 1456 SP--PLLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTP 1513

Query: 358  LEVTKLPVLE-NVSYMKQPAGASPSTLPSHVPGHAKLEK---EQAAALG----------- 402
            LEV KLPVLE N+ Y  QP G+SP +     P ++K +K   ++ A+ G           
Sbjct: 1514 LEVKKLPVLETNLKYPVQPEGSSPLS-----PQYSKSQKGDGDRPASPGLALFNGSGRAS 1568

Query: 403  PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAV 460
            P S  P     P PP   YR  +   +P      P+PV+ G++       +  P P  A 
Sbjct: 1569 PPSTPPPPPPPPGPPPAPYRPCAHLAFP----PEPAPVNAGKAGPSAEAPKVHPKPNSAP 1624

Query: 461  HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS 520
             +G  S S P +P+S  +    D  K  ++A      +P  SR    +SPL+EL SLF+S
Sbjct: 1625 VAGPCS-SFPKIPYSPVKATRADARKAGSSASPPAPYSPPSSRPL--SSPLDELASLFNS 1681

Query: 521  GRSLLRKSSSGRRSKEPAEKSTEELKVRSH----STEPLPKLDNKERGHHGASSS 571
            GRS+LRKS++GR+ +E AE     + + S     ++E   +  ++   +HG   S
Sbjct: 1682 GRSVLRKSAAGRKIRE-AEGFETNMNISSRDDPSTSEITSETQDRNANNHGIQLS 1735


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score =  209 bits (532), Expect = 6e-54
 Identities = 160/451 (35%), Positives = 206/451 (45%), Gaps = 95/451 (21%)

Query: 54  NLAYLKEKNEKRRRQEEAIKR-----------IGGEVGRG-----HEGSYVGKHFRMGFM 97
           NL Y K K E R+ +EE  KR            G   G+G      + + + +  RMGFM
Sbjct: 2   NLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFM 61

Query: 98  TMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDD------DSSCG-----SRRQPPPKPKRD 146
           TMPA Q+  PHPC S  + RS S HSVG  D        +S G     S R+PP KP+R 
Sbjct: 62  TMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRH 121

Query: 147 PSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
           PSTKLS           S +   P +   S KP P   E S+K+PP KP+R+PNTQLS S
Sbjct: 122 PSTKLSMVGP------GSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVS 175

Query: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPE---EEEPVYIEMVGNILRDFRK----- 258
           FDE+      PR  +LP    L++    AGDP+   +EEPVYIEMVG++ R   +     
Sbjct: 176 FDESCPPGPSPRGGNLPL-QRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGL 234

Query: 259 -----------------EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTV 301
                             D ++SEA+YEEMKYP+ ++ G+         + +S    P  
Sbjct: 235 AGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHA 294

Query: 302 --PDLDFAKASV------PCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDES 353
             P      AS         P K   C+IPPPFPNLL HRPPLL FP A        D  
Sbjct: 295 LPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGD-- 352

Query: 354 PLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS 413
                 V++LPVL    + K+PAG++P                  A   PA         
Sbjct: 353 -----GVSRLPVL---CHSKEPAGSTP------------------APQVPARERETPPPP 386

Query: 414 PPPPSTLYRTQSPHGYPKSHSTSPSPVSMGR 444
           PPPP+       P G  +SHST   P   G+
Sbjct: 387 PPPPAANLLLLGPSGRARSHSTPLPPQGSGQ 417



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 104/398 (26%), Positives = 148/398 (37%), Gaps = 84/398 (21%)

Query: 290 HSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLL---------SHRPPL---- 336
           HS     +TP  P +   +   P PP       PPP  NLL         SH  PL    
Sbjct: 362 HSKEPAGSTPA-PQVPARERETPPPPP------PPPAANLLLLGPSGRARSHSTPLPPQG 414

Query: 337 -------LVFPPAPVHCSPNSDESPLTPLEVTKL----PVLENVSYMKQPAGASPST--- 382
                     P +     P +  +P  P     L    P  + VSY    +    +T   
Sbjct: 415 SGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSV 474

Query: 383 LPSHVP---GHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHG----------Y 429
           LP+  P   G  K EKE +   G        SS PP P       SPHG          +
Sbjct: 475 LPAGPPLGAGEPKTEKEISVLHGMLCT----SSRPPVPGKT----SPHGGAMGAAAGVLH 526

Query: 430 PKSHSTSPS--PVSMGRSLTPL--------SLKRPPPYDAVHSGSLSRSSPSVPHSTPRP 479
            +    SP   P      LTPL         LKRPP Y+++ +G +      V   +P  
Sbjct: 527 HRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMV 586

Query: 480 VSQ------DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEEL-TSLFSSGRSLLRKSSSGR 532
             Q      DG    + +     A+ G     TP    EE+  + F +G +L RK   G 
Sbjct: 587 KIQLQEQGTDGGAFASISCAHVIASAG-----TPEEEEEEVGAATFGAGWALQRKVLYGG 641

Query: 533 RSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSR 592
           R  +  +K  +  +  + S E   K++ ++R   G  +S  PV++Q  +G         R
Sbjct: 642 RKAKELDKVEDGARAWNGSAEGPGKVEREDR---GPGTSGIPVRSQGAEGLLARIHHGDR 698

Query: 593 LGRCSVSP----TLLAGNHSSEPKVSCKLGRSASTSGV 626
            G  +  P    T  A + + +     +LGRSASTSGV
Sbjct: 699 GGSRTALPIPCQTFPACHRNGDFTGGYRLGRSASTSGV 736


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 135/608 (22%), Positives = 198/608 (32%), Gaps = 98/608 (16%)

Query: 100  PAPQDRLPH------PCSSGFSVRSQSLH--------------SVGGTDDDSSCGSRRQP 139
            PAP   LPH      P +S FSV +Q  H              S  G+   S  G    P
Sbjct: 514  PAPPP-LPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFP 572

Query: 140  PP------------------KPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR- 180
            PP                   P+  P   L+ +      ++  ++     R   S +PR 
Sbjct: 573  PPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRV 632

Query: 181  --PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDP 238
              P + E     PPP P       +     E  +   GPR    P      Q   PA   
Sbjct: 633  SFPKTPEVGPG-PPPGPLSKAPQPVPPGVGE--LPARGPRLFDFPPTPLEDQFEEPA--- 686

Query: 239  EEEEPVYIEMVGNILR----DFRKEDDDQSEAVYEEMKYPI---FDDLGQDAKCDFDHHS 291
              E  +  + + NI++      RKE++ Q        + P+   F  L      D    +
Sbjct: 687  --EFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTT 744

Query: 292  CSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSD 351
             +   A  T         +     K     +PPP P L    PP    PP P   SP S 
Sbjct: 745  TAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPP-PPLAKFPPPSQPQPPPPPPPSPAS- 802

Query: 352  ESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPG--HAKLEKEQAAALGPASATPA 409
                  L  +   VLE   Y  +  GA+ ST P  +P   ++      A AL P SA P+
Sbjct: 803  ------LLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPS 856

Query: 410  LSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSS 469
               SP P ++     S  G P +         +   +TP   + PPP     + S S   
Sbjct: 857  AQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTP--TQPPPPLSLPPARSESEVL 914

Query: 470  PSVPHSTPRPVSQDGAKMVNAA--VNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRK 527
              +  +    V + G    + A  V+T   A  G+    P +  +E      +G      
Sbjct: 915  EEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKE-----EAGGVAAVS 969

Query: 528  SSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTP 587
             S  RR KE  ++     +    S    P+              R   KA+        P
Sbjct: 970  GSCKRRQKEHQKEHRRHRRACKDSVGRRPR------------EGRAKAKAK-------VP 1010

Query: 588  VVTSR--LGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQV 645
               SR  LG   +    + G   S P +         T+  PP +  P  Q +    + V
Sbjct: 1011 KEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTP-PSASV 1069

Query: 646  PSSLANRD 653
            P   A  +
Sbjct: 1070 PGKKAREE 1077



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 77/347 (22%), Positives = 109/347 (31%), Gaps = 51/347 (14%)

Query: 315 PKGLLCDIPPPFPNLLSHRPPLLVFPPA----PVHCSPNSDESPLT--------PLEVTK 362
           P G     PPP P LL  RPP    PPA    P   +   D   L         P     
Sbjct: 462 PPGPSSPPPPPCPRLL--RPPP---PPAWLKGPACRAAREDGEILEELFFGTEGPPRPAP 516

Query: 363 LPVLENVSYMKQPAGA-SPSTLPSHVP----------GHAKLEKEQAAALGPASATP--- 408
            P+     ++  PA   S  T  SH P           ++      ++  GP S  P   
Sbjct: 517 PPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPY 576

Query: 409 ---ALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSL 465
              ++   P PPS     Q P   P + +  P+P S     T  S +RP       S   
Sbjct: 577 LARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRP------ESPRP 630

Query: 466 SRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAP--GGSRSRTPTSPLEELTSLFSSGRS 523
             S P  P   P P     +K         G  P  G      P +PLE+     +  + 
Sbjct: 631 RVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKI 690

Query: 524 LLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGT 583
           L    ++  +  + + +  EE +       P P L          +S + P      D  
Sbjct: 691 LPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP------FASLQSPFPT---DTA 741

Query: 584 PGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPPS 630
           P T      +   + + T        E K    L      +  PPPS
Sbjct: 742 PTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPS 788


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 112/469 (23%), Positives = 179/469 (38%), Gaps = 56/469 (11%)

Query: 102 PQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSST 161
           PQ  L  P SS FS    SL         S+     Q P         ++  SS + SST
Sbjct: 439 PQSPLQIPVSSSFSYTLLSLFQSSPERTHSTFEGFPQSP--------LQIPVSSSSSSST 490

Query: 162 AASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFD--ETYIKKHGPRR 219
             S    +PE T+++ +  P S     + PP     +   Q+  S    E  +  H   +
Sbjct: 491 LLSLFQSSPECTQSTFEGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQ 550

Query: 220 TSLPRDSSLSQMGSPAGDPEEEE-------PVYIEMVGNILRDFRKEDDDQSEAVYEEMK 272
           +    + SLS    P   P+ E+       P   +   ++   +  +   Q E     + 
Sbjct: 551 SPPQGEDSLSPHYFPQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLY 610

Query: 273 YPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSH 332
           +P     G++ +            +TP+     F ++S   PP+G     P   P     
Sbjct: 611 FPQSPLQGEEFQSSLQSPVSICSSSTPSSLPQSFPESS-QSPPEG-----PVQSPLHSPQ 664

Query: 333 RPPLLVFPPAPVHCSPNS---DESPLTPLEVTKLPV-----LENVSYMKQPAGASPSTLP 384
            PP  +   +P+  SP S    E  L+PL++ + P+     L ++ + + P     S  P
Sbjct: 665 SPPEGMHSQSPLQ-SPESAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSP 723

Query: 385 SHVPGH-AKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSP--SPVS 441
            H P    + E  Q++   P S   + +S   P S     +SP   P+  + SP   PVS
Sbjct: 724 LHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSF---PESPQSPPEGPAQSPLQRPVS 780

Query: 442 MGRSLTPLSL-------KRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNT 494
              S T  SL        + PP     S  L     S P ST   +SQ      ++ V++
Sbjct: 781 SFFSYTLASLLQSSHESPQSPPEGPAQS-PLQSPVSSFPSSTSSSLSQ------SSPVSS 833

Query: 495 YGAAPGGSRSR-TPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKST 542
           + ++   S S+ +P SPL+     FSS  SL   S     S  P ++ T
Sbjct: 834 FPSSTSSSLSKSSPESPLQSPVISFSSSTSL---SPFSEESSSPVDEYT 879



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 51/199 (25%), Positives = 73/199 (36%), Gaps = 48/199 (24%)

Query: 375 PAGASPSTLPSHVPGHAKLEKEQAAALGPASATPAL--SSSPPPPSTLYRTQSPHGYPKS 432
           P    PS L S        E  Q+   G  S +P     SSP    TLY  QSP    + 
Sbjct: 7   PTAGMPSLLQS------SSESPQSCPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEG 60

Query: 433 HSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAV 492
             +S              L+RPP       G  S+S   +P S+P     +G    +   
Sbjct: 61  EDSSD------------PLQRPP------EGKDSQSPLQIPQSSP-----EGDDTQSPLQ 97

Query: 493 NTYGAAPGGSRSRTP-------------TSPLEELTSLFSSGRSLLRKSSSGRRSKEPAE 539
           N+  ++P G  S +P              SPL+   S F S   L    SS   ++ P E
Sbjct: 98  NSQ-SSPEGKDSLSPLEISQSPPEGEDVQSPLQNPASSFFSSALLSIFQSSPESTQSPFE 156

Query: 540 ---KSTEELKVRSHSTEPL 555
              +S  ++ V + S+  L
Sbjct: 157 GFPQSVLQIPVSAASSSTL 175


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 153/613 (24%), Positives = 217/613 (35%), Gaps = 135/613 (22%)

Query: 100 PAPQDRLPHPCSSG--FSVRSQSLHSVGGTDDDSSCGSRRQPPPKP--KRDPSTKLSTSS 155
           PAP  R P P + G   SV S S HS      + S  +RR+P      +R  S  LS+S+
Sbjct: 192 PAPSAR-PRPPTEGPRKSVSSASEHST----TEPSPAARRRPSAGGGLQRPASRSLSSSA 246

Query: 156 ETVSSTAAS--KSGKTPERTEASAKPRPHSDEYSK--KIPPPKPKRNP------NTQLST 205
             +SS A S   +  TP      ++P+P   +  +  ++ PP+    P      ++ L+T
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 206 SFDETYIKKHGPRRT-SLPRDSSLS-QMGSPA--GDPEEEEPVYIEMVGNILRDFRKEDD 261
                 ++   P    + P  SSL+ Q+ +P     P    P  ++ + +          
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS------PPAT 360

Query: 262 DQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCD 321
             S+A            LG                     P L    + +P PP   L  
Sbjct: 361 PPSQAT---------TSLGS--------------------PTLQATHSFLPSPPLSPLAT 391

Query: 322 IPPPFPNLLSHRPPLLV--FPPAPVHCSPNSDESPLTP--LEVTKL----------PVLE 367
            PP  P  L+  PPL     PPA    SP +  SP  P  L V  L          PV  
Sbjct: 392 PPPQAPPALA-LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPS-------TL 420
             S    P  +  +T PS  P        Q     PAS   + S++PPP +        L
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510

Query: 421 YRTQSPHGYPKSHSTSP--------------SPVSMGRSLTPLSLKRPPPY-DAVHSGSL 465
              + P   P + +T P              +P S   SL    L  PPP    V +  L
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570

Query: 466 SRSSPSVPHSTP-----RPVSQDGAKMVNAAVNTYGAAPG--GSRSRTPTSPLEELTSLF 518
            +  PS P S       RP +      V+    T   APG     SR+P+S L       
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL------- 623

Query: 519 SSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTE----PLPKLDNKERGHHGASSSREP 574
            SG  L   SSS       A  + EEL+      E      P  D +    H A+ SR P
Sbjct: 624 -SGPDLAGHSSS-------ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675

Query: 575 VKAQEWDGTPGTPV-------VTSRLGRCSV-------SPTLLAGNHSSEPKVSCKLGRS 620
                + G PG P+         S  G C++       S T   G     P      G++
Sbjct: 676 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKA 735

Query: 621 ASTSGVPPPSVTP 633
           A+ +G    S +P
Sbjct: 736 AAGAGAGASSRSP 748



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 88/374 (23%), Positives = 127/374 (33%), Gaps = 73/374 (19%)

Query: 327 PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS---YMKQPAGASPSTL 383
           P LL+ RPP    PP PV           TP  +  L     V      ++  G   +T+
Sbjct: 22  PGLLTPRPPGSPRPPPPV-----------TPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 384 PSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYP--KSHSTSPSP-- 439
           P   P          ++  PAS  PA       P     +  P   P   S +T P P  
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130

Query: 440 -----VSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNT 494
                +S   ++        P   A+ +G+   +S   P  TP P     ++     V  
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGL 189

Query: 495 YGAAPGGSRSRTPTSPLEELTSLFSS------GRSLLRKSSSGRRSKEPAEKSTEEL--- 545
              AP  +R R PT    +  S  S         +  R+ S+G   + PA +S       
Sbjct: 190 PRPAP-SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248

Query: 546 ---------------KVRSHSTEPLPKLDNKERGHHGASSSREP-VKAQEWDGTPGT-PV 588
                          +  +H ++P PK         G  + R P V     D  P   P+
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPK---------GLQALRPPQVTPPRKDAAPALGPL 299

Query: 589 VTSRLGRCSVS--------PTLLAGNHSSEPKVSCKLGRS---ASTSGVPPPSVTPLRQS 637
            +S L   S S        PTL A  HSS   ++C+L      A  S   PPS+  L   
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSS--SLTCQLATPLPLAPPSPSAPPSLQTLPSP 357

Query: 638 SDLQQSQVPSSLAN 651
                SQ  +SL +
Sbjct: 358 PATPPSQATTSLGS 371


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 148/604 (24%), Positives = 206/604 (34%), Gaps = 147/604 (24%)

Query: 100 PAPQDRLPHPCSSG--FSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTK---LSTS 154
           PAP  R P P + G   SV S S HS              +P P  +R PS        +
Sbjct: 183 PAPSAR-PRPPTEGPRKSVSSASEHST------------TEPSPAARRRPSAGGGLQRPA 229

Query: 155 SETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKK 214
           S ++SS+A   S  +P R+  SA+  P +  +  +   PKPK               ++ 
Sbjct: 230 SRSLSSSATPLS--SPARSGPSARGTPRAPAHPSQ---PKPKG--------------LQA 270

Query: 215 HGPRRTSLPRDSSLSQMG----SPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEE 270
             P + + PR  +   +G    SP   P    P                    +    + 
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP----------------PSPSAPPSLQT 314

Query: 271 MKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLL 330
           +  P      Q           ++   +PT   L    + +P PP   L   PP  P  L
Sbjct: 315 LPSPPATPPSQ----------ATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 331 SHRPPLLV--FPPAPVHCSPNSDESPLTP--LEVTKL----------PVLENVSYMKQPA 376
           +  PPL     PPA    SP +  SP  P  L V  L          PV    S    P 
Sbjct: 362 A-LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420

Query: 377 GASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPS-------TLYRTQSPHGY 429
            +  +T PS  P        Q     PAS   + S++PPP +        L   + P   
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480

Query: 430 PKSHSTSP--------------SPVSMGRSLTPLSLKRPPPY-DAVHSGSLSRSSPSVPH 474
           P + +T P              +P S   SL    L  PPP    V +  L +  PS P 
Sbjct: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540

Query: 475 STP-----RPVSQDGAKMVNAAVNTYGAAPG--GSRSRTPTSPLEELTSLFSSGRSLLRK 527
           S       RP +      V+    T   APG     SR+P+S L        SG  L   
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL--------SGPDLAGH 592

Query: 528 SSSGRRSKEPAEKSTEELKVRSHSTE----PLPKLDNKERGHHGASSSREPVKAQEWDGT 583
           SSS       A  + EEL+      E      P  D +    H A+ SR P     + G 
Sbjct: 593 SSS-------ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 645

Query: 584 PGTPV-------VTSRLGRCSV-------SPTLLAGNHSSEPKVSCKLGRSASTSGVPPP 629
           PG P+         S  G C++       S T   G     P      G++A+ +G    
Sbjct: 646 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 705

Query: 630 SVTP 633
           S +P
Sbjct: 706 SRSP 709



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 81/336 (24%), Positives = 119/336 (35%), Gaps = 54/336 (16%)

Query: 327 PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS---YMKQPAGASPSTL 383
           P LL+ RPP    PP PV           TP  +  L     V      ++  G   +T+
Sbjct: 22  PGLLTPRPPGSPRPPPPV-----------TPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 384 PSHVP--GHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSP-- 439
           P   P  G  +  +  A+  G   A PA ++SP P S+  R         S +T P P  
Sbjct: 71  PESAPRAGPTRTSRPPASGRG-ERAPPAKNTSPGPVSSPGRA--------SGTTRPGPLG 121

Query: 440 -----VSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNT 494
                +S   ++        P   A+ +G+   +S   P  TP P     ++     V  
Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGL 180

Query: 495 YGAAPGGSRSRTPT-SPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTE 553
              AP  +R R PT  P + ++S  +S  S    S + RR +  A    +    RS S+ 
Sbjct: 181 PRPAP-SARPRPPTEGPRKSVSS--ASEHSTTEPSPAARR-RPSAGGGLQRPASRSLSSS 236

Query: 554 PLPKLDNKERGHHGASSSREPVKAQE-----------WDGTPGTPVVTSRLGRCSVSPTL 602
             P       G     + R P    +              TP        LG  S SP L
Sbjct: 237 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-L 295

Query: 603 LAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSS 638
              + S+ P  S       S   +P P  TP  Q++
Sbjct: 296 ATPSPSAPPSPSA----PPSLQTLPSPPATPPSQAT 327


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 86/336 (25%), Positives = 118/336 (35%), Gaps = 72/336 (21%)

Query: 314 PPKGLLCDIPPPFPNLLSHR---PPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS 370
           PP+     +PPP P++ S     PP +   P P+  SP++  SP  P             
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207

Query: 371 YMKQPAGASPSTLPSHVPGHAKLEKEQAAALG-------PASATPALSSSPPPPSTLYRT 423
               P   SP   P   PG+      +  ALG       P S++   S+ PP P T  R 
Sbjct: 208 --GGPRQPSPGPTPPPFPGN------RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQD 483
                 P      P PV    S+   ++  PPP           + P VP STPRP +  
Sbjct: 260 LDDKPPP-----PPPPVGNRPSIHREAVPPPPP---------QNNKPPVP-STPRPSASS 304

Query: 484 GAKMVNAAVNTYGAAP----GGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAE 539
            A       +  G  P          TP  P   L SL SS   L     SG     P+E
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL-SLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 540 KSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVS 599
           +    ++     + PLP      R     S+SR           P TP + SR G     
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSR---NGSTSR---------ALPATPQLPSRSG----- 406

Query: 600 PTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLR 635
                 +  S P+      R ++ +  PPP  T +R
Sbjct: 407 ----VDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIR 438



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 52/179 (29%), Positives = 69/179 (38%), Gaps = 37/179 (20%)

Query: 311 VPCPPKGLLCDIPPPFPNLLSHRPPL---LVFPPAPVHCSPNSDESPLTPLEVTKLPVLE 367
           +P  P   L D PPP P  + +RP +    V PP P +  P    +P  P   ++ P   
Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAP--- 307

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS------PPPPSTLY 421
                  P+   P  LP    G+ +  +     L  +S+TP L S       PPPPS   
Sbjct: 308 --PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS--- 362

Query: 422 RTQSPHGYPKSHSTSPSPV--SMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPR 478
                          P PV    GRS  PL    PPP     +GS SR+ P+ P    R
Sbjct: 363 ------------ERPPPPVRDPPGRS-GPL----PPPPPVSRNGSTSRALPATPQLPSR 404



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 63/237 (26%), Positives = 83/237 (35%), Gaps = 28/237 (11%)

Query: 412 SSPP--PPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAVHSGSLSR 467
           S PP  PP     +  P   P      P P    RS  P   +   PPP   V  GS   
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDV--GSKPD 181

Query: 468 SSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSR--SRTPTSPLEELTSLFSSGRSLL 525
           S P    STPRP+        +  V      PGG R  S  PT P        + G   +
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPV------PGGPRQPSPGPTPPPFPGNRGTALGGGSI 235

Query: 526 RK---SSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGA------SSSREPV- 575
           R+   SSS   S  P    T    +      P P + N+   H  A       +++ PV 
Sbjct: 236 RQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVP 295

Query: 576 ---KAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPP 629
              +       P  P   SR G   + P+  +GN  +       L  S+ST  +P P
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPS-SSGNDETPRLPQRNLSLSSSTPPLPSP 351


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 86/336 (25%), Positives = 118/336 (35%), Gaps = 72/336 (21%)

Query: 314 PPKGLLCDIPPPFPNLLSHR---PPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS 370
           PP+     +PPP P++ S     PP +   P P+  SP++  SP  P             
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207

Query: 371 YMKQPAGASPSTLPSHVPGHAKLEKEQAAALG-------PASATPALSSSPPPPSTLYRT 423
               P   SP   P   PG+      +  ALG       P S++   S+ PP P T  R 
Sbjct: 208 --GGPRQPSPGPTPPPFPGN------RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQD 483
                 P      P PV    S+   ++  PPP           + P VP STPRP +  
Sbjct: 260 LDDKPPP-----PPPPVGNRPSIHREAVPPPPP---------QNNKPPVP-STPRPSASS 304

Query: 484 GAKMVNAAVNTYGAAP----GGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAE 539
            A       +  G  P          TP  P   L SL SS   L     SG     P+E
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL-SLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 540 KSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVS 599
           +    ++     + PLP      R     S+SR           P TP + SR G     
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSR---NGSTSR---------ALPATPQLPSRSG----- 406

Query: 600 PTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLR 635
                 +  S P+      R ++ +  PPP  T +R
Sbjct: 407 ----VDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIR 438



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 52/179 (29%), Positives = 69/179 (38%), Gaps = 37/179 (20%)

Query: 311 VPCPPKGLLCDIPPPFPNLLSHRPPL---LVFPPAPVHCSPNSDESPLTPLEVTKLPVLE 367
           +P  P   L D PPP P  + +RP +    V PP P +  P    +P  P   ++ P   
Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAP--- 307

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS------PPPPSTLY 421
                  P+   P  LP    G+ +  +     L  +S+TP L S       PPPPS   
Sbjct: 308 --PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS--- 362

Query: 422 RTQSPHGYPKSHSTSPSPV--SMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPR 478
                          P PV    GRS  PL    PPP     +GS SR+ P+ P    R
Sbjct: 363 ------------ERPPPPVRDPPGRS-GPL----PPPPPVSRNGSTSRALPATPQLPSR 404



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 63/237 (26%), Positives = 83/237 (35%), Gaps = 28/237 (11%)

Query: 412 SSPP--PPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAVHSGSLSR 467
           S PP  PP     +  P   P      P P    RS  P   +   PPP   V  GS   
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDV--GSKPD 181

Query: 468 SSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSR--SRTPTSPLEELTSLFSSGRSLL 525
           S P    STPRP+        +  V      PGG R  S  PT P        + G   +
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPV------PGGPRQPSPGPTPPPFPGNRGTALGGGSI 235

Query: 526 RK---SSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGA------SSSREPV- 575
           R+   SSS   S  P    T    +      P P + N+   H  A       +++ PV 
Sbjct: 236 RQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVP 295

Query: 576 ---KAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPP 629
              +       P  P   SR G   + P+  +GN  +       L  S+ST  +P P
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPS-SSGNDETPRLPQRNLSLSSSTPPLPSP 351


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 120/557 (21%), Positives = 176/557 (31%), Gaps = 115/557 (20%)

Query: 102 PQDRLPHP-----CSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSE 156
           P  R+P P       S    R +S  S+ G+   SS    R PP KP +       TSS 
Sbjct: 328 PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPK------RTSSP 381

Query: 157 TVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHG 216
              +   S S   P R    + P           PPPK + +P  Q S    ++ +    
Sbjct: 382 PRKTRRLSPSASPPRRRHRPSPP---------ATPPPKTRHSPTPQQSNRTRKSRVSV-S 431

Query: 217 PRRTS--LPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYP 274
           P RTS  + +     +  SP+  P+  +    E   +        D  Q    Y      
Sbjct: 432 PGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQ 491

Query: 275 IFDDLGQDAKCDFDHHSCS---------------SQCATPTVPDLDFAKASVPCPPKGLL 319
              D G  +  + +    S               S+ A+P+       K      P+G  
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP-----RKRQKETSPRGRR 546

Query: 320 CDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGAS 379
              P P P      P      PAP    P    +P  P                 P   +
Sbjct: 547 RRSPSPPPTRRRRSP-----SPAP---PPRRRRTPTPP-----------------PRRRT 581

Query: 380 PSTLP-SHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPS 438
           PS  P    P   +          P+      ++SPPPP     + SP   P     S S
Sbjct: 582 PSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP---PPKRRVSHS 638

Query: 439 PVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAA 498
           P    RS +P++ +R P   + H    S S  +    +P+P                   
Sbjct: 639 PPPKQRS-SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQP------------------- 678

Query: 499 PGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEP---- 554
                 R   SP        SS   + R +SS  + ++    ST  ++  S + EP    
Sbjct: 679 ----NKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIK 734

Query: 555 ---LPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHSSEP 611
               P   +  R     S S  P  A +    P +PV        S SP+      +  P
Sbjct: 735 KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ-------SQSPST-----NWSP 782

Query: 612 KVSCKLGRSASTSGVPP 628
            V  K  +S + S  PP
Sbjct: 783 AVPVKKAKSPTPSPSPP 799



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 101/463 (21%), Positives = 164/463 (35%), Gaps = 65/463 (14%)

Query: 136 RRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKP 195
           R +P P     P T+ S + +  + T  S+   +P RT         +++     P PKP
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457

Query: 196 KRNPNTQLSTSFDETYIKKHG-----PRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVG 250
           ++    +LS S ++   K         RR    ++   S     +   E+E P    +  
Sbjct: 458 RK---VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKN 514

Query: 251 NILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKAS 310
             +   R+    +S +     +       G+  +             +P+ P     ++ 
Sbjct: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR-------------SPSPPPTRRRRSP 561

Query: 311 VPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDE--SPLTPLEVTKLPVLEN 368
            P PP       P P P   +  PP     P+P   SP      SP  P      P    
Sbjct: 562 SPAPPPRRR-RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP------PKRRT 614

Query: 369 VSYMKQP-AGASPSTLPSHVPGHAKLEKEQAAALGPASATPALS------SSPPPPSTLY 421
            S    P   ASPS  P     H+   K++++ +     +P+LS      SSP   +   
Sbjct: 615 ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV-TKRRSPSLSSKHRKGSSPSRSTREA 673

Query: 422 RTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVP-------H 474
           R+  P+   K HS SP P +   S +P     PP      S    R SPS          
Sbjct: 674 RSPQPN---KRHSPSPRPRAPQTSSSP-----PPVRRGASSSPQRRQSPSPSTRPIRRVS 725

Query: 475 STPRP--------VSQDGAKMVNAAVNTYGA-APGGSRSRTPTSPLE-ELTSLFSSGRSL 524
            TP P         S    + V+++ +  G+  P   +   P SP++ +  S   S    
Sbjct: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785

Query: 525 LRKSSSGRRSKEPAEKSTEE--LKVRSHSTEPLPKLDNKERGH 565
           ++K+ S   S  P   S +E   K +    +   K D K + H
Sbjct: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKH 828



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 71/264 (26%), Positives = 99/264 (37%), Gaps = 31/264 (11%)

Query: 407 TPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR------PPPYDAV 460
           +P+ S+SP P      T SP G  +  S SP P    RS +P    R      PPP    
Sbjct: 524 SPSRSASPSPRKRQKET-SPRGR-RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581

Query: 461 HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFS- 519
            S    R SPS    +P P+ +  +        T    P   R  +P+ P +   S    
Sbjct: 582 PSPPPRRRSPSPRRYSP-PIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640

Query: 520 ----SGRSLLRKS---SSGRRSKEPAEKSTEELKV----RSHSTEPLPKLDNKERG---- 564
               S     R+S   SS  R      +ST E +     + HS  P P+           
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700

Query: 565 HHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTS 624
             GASSS  P + Q    +P T  +  R+ R +  P  +    S  P+   ++  S S S
Sbjct: 701 RRGASSS--PQRRQS--PSPSTRPIR-RVSR-TPEPKKIKKAASPSPQSVRRVSSSRSVS 754

Query: 625 GVPPPSVTPLRQSSDLQQSQVPSS 648
           G P P+           QSQ PS+
Sbjct: 755 GSPEPAAKKPPAPPSPVQSQSPST 778



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 102/452 (22%), Positives = 147/452 (32%), Gaps = 77/452 (17%)

Query: 137 RQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEA-SAKPRPHSDEYSKKIPPPKP 195
           R P  +  R PS +   SS        S S     RT++ S  P P   E + ++P P  
Sbjct: 170 RSPRRRKSRSPSPR-RRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV 228

Query: 196 K-RNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILR 254
           K + P+ Q +TS                   S + ++  P   PE +EP           
Sbjct: 229 KVKEPSVQEATS------------------TSDILKVPKPEPIPEPKEP----------- 259

Query: 255 DFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCP 314
               E + + E   E+ +        +            S+  + T P       S    
Sbjct: 260 --SPEKNSKKEKEKEKTR-------PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYS 310

Query: 315 PKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQ 374
           P+        P P     R P    PP P H    S             PV         
Sbjct: 311 PRRRPSPRRRPSPR---RRTPPRRMPPPPRHRRSRS-------------PVRRRRRSSAS 354

Query: 375 PAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHS 434
            +G+S S+  S      K   ++ ++  P   T  LS S  PP   +R   P   P    
Sbjct: 355 LSGSSSSSSSSRSRSPPKKPPKRTSS--PPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412

Query: 435 TSPSPVSMGR---SLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAA 491
            SP+P    R   S   +S  R       H G+  R SPS     P+P   + ++     
Sbjct: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS---PAPKPRKVELSESEEDK 469

Query: 492 VNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSH- 550
                AA    + R      ++ +S   SG S    SS   R K    K+ E  + R H 
Sbjct: 470 GGKMAAADSVQQRRQYRRQNQQSSS--DSGSS---SSSEDERPKRSHVKNGEVGRRRRHS 524

Query: 551 ---STEPLPKLDNKE---RGHHGASSSREPVK 576
              S  P P+   KE   RG    S S  P +
Sbjct: 525 PSRSASPSPRKRQKETSPRGRRRRSPSPPPTR 556


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 101/460 (21%), Positives = 158/460 (34%), Gaps = 64/460 (13%)

Query: 140  PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNP 199
            PP PK  P+T     + T  +        +P        P P +      + PP PK  P
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA------VTPPSPKGTP 1347

Query: 200  NTQLSTSFDE----TYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRD 255
                +T   +    T   K GP     P  ++ S  G PA  P   +       G  +  
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPT----PPAATPSHKGGPAMTPPSPKR------GPAIPS 1397

Query: 256  FRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPP 315
             + +    +       K P      + A               P V  +   KA     P
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATP-----SKGDLTPPAVTPVSLKKAPATSAP 1452

Query: 316  KG-LLCDIPPPFPNLLSHRPPLLVFPPAP--VHCSPNSDESPLTP--LEVTKLPVLENVS 370
            KG          P L +  PP    PPAP  V  S +  ++P TP  +    LP +   S
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512

Query: 371  YMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASA-------------TPALSS---SP 414
              + PA  S    P   P    L K+  A L P  A             TPA+ +   +P
Sbjct: 1513 PKEVPATPSSRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP 1571

Query: 415  PPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPH 474
              PS+   +  P   P ++  +PSP  +   L P ++  P P +A    +++  SP    
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGAPSPKEL---LIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628

Query: 475  STPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRS 534
            +TP P     +  V  +          S   +PTSP     S+     + + ++S G  +
Sbjct: 1629 ATPAPKGTPTSPPVTPS----------SLKDSPTSP----ASVTCKMGATVPQASKGLPA 1674

Query: 535  KEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREP 574
            K+      E L   +  + P+     ++      SS+  P
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 112/512 (21%), Positives = 163/512 (31%), Gaps = 48/512 (9%)

Query: 141  PKPKRDPSTKLSTSSETVSSTAAS--KSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRN 198
            P PK  P+T     +  +S T++S  K+  TP      A P P          PP PK  
Sbjct: 894  PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953

Query: 199  PNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRK 258
            P T  S  +  T      P   + P         SP G P           G       K
Sbjct: 954  PATP-SPKWAPT------PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006

Query: 259  EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCP---P 315
                         K       G  A   F   + +   ATP  P    + A+ P P   P
Sbjct: 1007 GAPTPPAVTPPSPK-------GSPAATPFPKGASTPPAATP--PSPKGSPAATPLPKGAP 1057

Query: 316  KGLLCDIP-----PPFPNLLSHRPPLLVFPPAPV--HCSPNSDESPLTPLEVTKLPVLEN 368
                  +P     P  P+L     P    PP+P     +P+   +P+ P      P    
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117

Query: 369  VSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALS---SSPPPPSTLYRTQS 425
             +   + A  +P+  P    G       + A   PA+  P+     ++PPP        +
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177

Query: 426  PHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHST-PRPVSQDG 484
                PK    +PSP   G   TP +   P P   + + S  + +P+ P +T P P     
Sbjct: 1178 TPPSPKGGLATPSP--KGAPTTPAATP-PSPKGGLATPS-PKGAPTTPAATPPSPKGGLA 1233

Query: 485  AKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEE 544
                  A  T  A P   +    T P +       +  +    S  G  +  P + +   
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGA----PTPPAATPPSLKGGLATPPHKGAPNP 1289

Query: 545  LKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLLA 604
              V    T P PK         GA +           G+PGTP         +V+P    
Sbjct: 1290 AVV----TPPSPKGGPATSPPKGAPTPPAATPPSP-KGSPGTPPPKGAPTPPAVTPPSPK 1344

Query: 605  GNHSSEPKVSCKLG---RSASTSGVPPPSVTP 633
            G  +         G     +S  G  PP+ TP
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 80/346 (23%), Positives = 121/346 (34%), Gaps = 34/346 (9%)

Query: 298  TPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVH--CSPNSDESPL 355
            TPT+P    +    P  P       PP      SH+    + PP+P      P+    P 
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPT 1403

Query: 356  TPLEVTKLPVLENVSYMKQPAGASPS----TLPSHVPGHAKLEKEQAAALGPASATPALS 411
            +P  +   P     + + +   A+PS    T P+  P   K     +A  G   ATP+  
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPATPSSK 1462

Query: 412  SSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPS 471
              P  P+    +      PK  +TS SP     +  P+     P   AV   S  +  P+
Sbjct: 1463 GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA---PTLPAVIPSS-PKEVPA 1518

Query: 472  VPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSG 531
             P S   P++     +      T  A          T P  + T    + +      SS 
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATL-APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSK 1577

Query: 532  RRSKEPA--------EKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGT 583
              S  PA          S +EL +    T P PK    E     A +   P K       
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK----EAPTPPAVTPPSPEKGPATPAP 1633

Query: 584  PGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSA--STSGVP 627
             GTP          V+P+ L  + +S   V+CK+G +   ++ G+P
Sbjct: 1634 KGTPTSPP------VTPSSLKDSPTSPASVTCKMGATVPQASKGLP 1673



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 65/168 (38%), Gaps = 20/168 (11%)

Query: 340  PPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAA 399
            PP+P      S  +PL+P  VT  P        K+    S   LP    G A    +QA 
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPP--------KETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 400  ALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDA 459
            AL   S++P  + + P P  +  + SP G P   + +P P   G   TP     P P   
Sbjct: 910  ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-PSPKGGPATPSPKWAPTP--- 965

Query: 460  VHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTP 507
                    ++P  P   P   S  GA    AA  T  +  GG  + +P
Sbjct: 966  ------PAATPPSPKGGPATPSPKGAPTPPAA--TPPSPKGGPATPSP 1005



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 119/518 (22%), Positives = 165/518 (31%), Gaps = 69/518 (13%)

Query: 140  PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNP 199
            PP PK  P+T     + T  +         P      A P P        + PP PK +P
Sbjct: 970  PPSPKGGPATPSPKGAPTPPAATP------PSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023

Query: 200  NTQLSTSFDETYIKKHGPRRTSLPRDSSL-SQMGSPAGDPEEEEPVYIEMVGNILRDFRK 258
                +T F         P+  S P  ++  S  GSPA  P  +        G        
Sbjct: 1024 ---AATPF---------PKGASTPPAATPPSPKGSPAATPLPK--------GAPTTPAAT 1063

Query: 259  EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGL 318
                +       +K       G          S     ATP+        A+ P  PKG 
Sbjct: 1064 LPSPKGGPATPSLK-------GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116

Query: 319  LCDIP-----------PPFPNLLSHRPPLLVFP--PAPVHCSPNSDESPLTPLEVTKLPV 365
            L   P           PP P      PP    P  PA    SP    +   P      P 
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176

Query: 366  LENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQS 425
                S     A  SP   P+         K   A   P  A    +++PP P     T S
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236

Query: 426  PHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGA 485
            P G P + + +P P   G   TP     P P  A    SL     + PH         GA
Sbjct: 1237 PKGAPTTPAATP-PSPKGGPATPPPKGAPTP-PAATPPSLKGGLATPPHK--------GA 1286

Query: 486  KMVNAAVNTYGAAPGGSRSR----TPTSPLEELTS-LFSSGRSLLRKSSSGRRSKEPAEK 540
               N AV T  +  GG  +      PT P     S   S G    + + +      P+ K
Sbjct: 1287 P--NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344

Query: 541  STEELKVRSHSTEPLPKLDNKERG--HHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSV 598
             T  L   + S++  P   + + G     A+ S +   A         P + S  G    
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD-PT 1403

Query: 599  SPTLLAGNHSSEP--KVSCKLGRSASTSGVPPPSVTPL 634
            SP ++  +    P   V+ +   + S   + PP+VTP+
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 87/363 (23%), Positives = 127/363 (34%), Gaps = 42/363 (11%)

Query: 298  TPTVPDLDFA---KASVPCPPKGLLCDIPP---PFPNLLSHRPPLLVFP------PAPVH 345
            +PT P    A    A  P  PKG+   +PP   P P++++     L FP      PAP  
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVT--LPPKETPTPSVVN-----LPFPKEGPATPAPKQ 907

Query: 346  CSPNSDESPLTPLEVTKLPVLENVSYMKQPAGAS--PSTLPSHVPGHAKLEKEQAAALGP 403
             +P    +  +P +    P  + +     P GA   P+  P    G       + A   P
Sbjct: 908  -APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966

Query: 404  ASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSG 463
            A+  P+    P  PS       P   P S    P+  S   + TP ++  P P  +  + 
Sbjct: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026

Query: 464  SLSRSSPSVPHST-PRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGR 522
               + + + P +T P P     A  +     T  AA   S    P +P     SL   G 
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP-----SL--KGA 1079

Query: 523  SLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGA--------SSSREP 574
                 ++       PA  S +   +   +T P PK       H GA         S +  
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 575  VKAQEWDGTPGTPVVT--SRLGRCSVSPTLLAGNHSSEPKVSCKLG-RSASTSGVP-PPS 630
            +      G P TP  T  S  G  +  P   A    +    S K G  + S  G P  P+
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199

Query: 631  VTP 633
             TP
Sbjct: 1200 ATP 1202



 Score = 36.2 bits (82), Expect = 0.098
 Identities = 86/372 (23%), Positives = 125/372 (33%), Gaps = 62/372 (16%)

Query: 290  HSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNL--LSHRPPLLVFPPAPVHCS 347
            ++C+        P++  +  S   PP G     PP    +  +SH   L     +P  C 
Sbjct: 716  NTCAPLATLVLAPEIPKSVPSPSLPPAGT----PPGTKKVDGISHTSALAPVASSPKECP 771

Query: 348  PN--------SDESPLTPLEVTKLPVLENVS-YMKQP----AGASPST----LPSHV-PG 389
                      S +  LT L  +  P+  +VS   K+P      A P T    L S V P 
Sbjct: 772  TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831

Query: 390  HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPL 449
             A    E + +   +  +PA + SP PP       SP G P     +PS V      TPL
Sbjct: 832  EASFLPENSLSFQGSKDSPATTHSPTPP-------SPKGAP-----TPSAV------TPL 873

Query: 450  SLK--RPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTP 507
            S K    PP +      ++   P    +TP P       M +++     A P        
Sbjct: 874  SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933

Query: 508  TSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHG 567
             SP          G      ++       PA  S +       +T P PK         G
Sbjct: 934  PSP---------KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG 984

Query: 568  ASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVP 627
            A +           G P TP         +V+P    G+ ++ P      G S   +  P
Sbjct: 985  APTPPAATPPSP-KGGPATPSPKGAPTPPAVTPPSPKGSPAATP---FPKGASTPPAATP 1040

Query: 628  P-----PSVTPL 634
            P     P+ TPL
Sbjct: 1041 PSPKGSPAATPL 1052



 Score = 36.2 bits (82), Expect = 0.098
 Identities = 124/563 (22%), Positives = 173/563 (30%), Gaps = 112/563 (19%)

Query: 134  GSRRQPPPKPKRDP---STKLSTSSETVSSTAASKSGKTPERTEASAKPR------PHSD 184
            G     PP PKR P   S K   +S  V   +  K+  TP   E +A P       P   
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 185  EYSKKIPPPK--PKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEE 242
              S K  P    PK  P T  S+  D T      P     P    ++   SP   P    
Sbjct: 1440 PVSLKKAPATSAPKGGPATP-SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498

Query: 243  PVYIEMVGNILRDFRKE---------DDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCS 293
            P+    +  ++    KE         D     A     K P    L           +  
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA--TLAPKEALIPPAMTVP 1556

Query: 294  SQCATPTVPDLDFAKASVPCPPKGLLCDIPP---PFPNLLSHRPPLLVFPPAPVHCSPNS 350
            S   TP +P         P  P       PP   P     +  P  L+ PPA    SP  
Sbjct: 1557 SPKKTPAIP----TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612

Query: 351  DESP--LTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPAS--- 405
              +P  +TP    K P              +PS+L       A +  +  A +  AS   
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672

Query: 406  -------ATPALSSSPPPPSTLYRTQSPHGYP---KSHSTSP----SPVSMGRSLTPLSL 451
                   A   +  +P P ST   T      P   KS +TSP     P +   S  PLS 
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732

Query: 452  KRPPPY--------------DAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGA 497
              P P               DA HS     + P    STP   +     +      +  A
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792

Query: 498  APG--------------------------GSRSRTPTSPL-----EELTSLF-----SSG 521
            AP                           G    +P+ PL     +EL  L      S G
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852

Query: 522  ---RSLLRKSSSGRRS---------KEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGAS 569
               +S+L    + + +         K+P  K+ +     S S E +P+L+ ++      +
Sbjct: 1853 VPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQD-STQATT 1911

Query: 570  SSREPVKAQEWDGTPGTPVVTSR 592
               +   A E D  P +    SR
Sbjct: 1912 QQAQLAAAAEIDEEPVSKAKQSR 1934



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 41/157 (26%), Positives = 57/157 (36%), Gaps = 32/157 (20%)

Query: 340 PPAPVHCSPNSDESPL-----------------TPLEVTKLPVLENVSYMKQPAGASPST 382
           P  P  CSP   + PL                 TPLEV   P  ++ S    P G +P  
Sbjct: 43  PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEV---PFPQSSSGTALPLGTAPEA 99

Query: 383 LPSHVPGHAKLEKEQAAALGPASATPALS-SSPPPPSTLYRTQSPHGYPKSHSTSPSPVS 441
            P+ +P            +GP  +  AL+ +SP    TL  T S        + +P  V 
Sbjct: 100 -PTFLPN----------LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQ 148

Query: 442 MGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPR 478
              +  P  L  PP      SGS+   S  +  S P+
Sbjct: 149 KSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 125/531 (23%), Positives = 181/531 (34%), Gaps = 70/531 (13%)

Query: 140  PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNP 199
            PP  +  P++  +   E + S A       P +T ++    PH +  +   P P P + P
Sbjct: 520  PPSLQTPPASLTTPPLENLPSLAPP-----PLQTASAPLTTPHLE--TPPCPAPCPLQAP 572

Query: 200  NTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMG------SPAGDPEEEEPVYIEMVGNIL 253
             + L+T   ET      P   + P  +S    G      SP   P  + P  +      L
Sbjct: 573  PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA-----L 627

Query: 254  RDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPC 313
               +      +      +  P        A      H   +  + P  P +    +    
Sbjct: 628  PPLQAPPSPPASPPLSPLATP-----SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 314  PPKGLLCDIPPPFPNLLSHRPPLLV--FPPAPVHCSPNSDESPLTPLEVTKLPVLENVSY 371
            PP       P   P  L+  PPL V   PPA    SP++   P  P  +   P+    S 
Sbjct: 683  PPVSPSATPPSQAPPSLA-APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 372  MKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSP-HGYP 430
               P  +  +T P  VP        Q     PAS   +  + PPP +       P    P
Sbjct: 742  PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801

Query: 431  KSHSTSP--SPVSMGRSLTPLSLKRPPPY-DAVHSGSLSRSSPSVPHSTP-----RPVSQ 482
               ++ P  +P S   SL    L  PPP    V +  L +  PS P S       RP + 
Sbjct: 802  SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861

Query: 483  DGAKMVNAAVNTYGAAPG--GSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
                 V+    T   APG     SR+P+S L        SG  L   SSS       A  
Sbjct: 862  GPDTSVSGPRLTLALAPGPPPPPSRSPSSTL--------SGPDLAGHSSS-------ATS 906

Query: 541  STEELKVRSHSTE----PLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPV-------V 589
            + EEL+      E      P  D +    H A+ SR P     + G PG P+        
Sbjct: 907  TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP 966

Query: 590  TSRLGRCSV-------SPTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTP 633
             S  G C++       S T   G     P      G++A+ +G    S +P
Sbjct: 967  GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 92/382 (24%), Positives = 134/382 (35%), Gaps = 45/382 (11%)

Query: 140 PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR------PHSDEYSKKIPPP 193
           PP P   PS +   S      + A  S  TP      +         PHS        PP
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404

Query: 194 KPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDS--SLSQMGSPAGDPEEEEPVYIEMVGN 251
            P    + Q +TS     ++      T  PR +  SL+    PA  P +  P+   +   
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS-- 462

Query: 252 ILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLD----FA 307
            L          S AV   +  P+     Q A      HS  +  ++  +P L+     A
Sbjct: 463 -LPASPPLQTSLSPAV-SPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSSLA 519

Query: 308 KASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLE 367
             S+  PP  L     PP  NL S  PP L    AP+  +P+ +  P         P+  
Sbjct: 520 PPSLQTPPASLTT---PPLENLPSLAPPPLQTASAPL-TTPHLETPPCP----APCPLQA 571

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPH 427
             S +  P   +PS++ +  P        QA    PA A+P L   P PP +   T  P 
Sbjct: 572 PPSPLTTPPPETPSSIATPPP--------QAP---PALASPPLQGLPSPPLSPLATPPPQ 620

Query: 428 GYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKM 487
                   +P  +++     P S    PP   + + S    +    H    P S   +  
Sbjct: 621 --------APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672

Query: 488 VNAAVNTYGAAPGGSRSRTPTS 509
           V A  +   A+P  S S TP S
Sbjct: 673 VQAPFSP-PASPPVSPSATPPS 693



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 82/301 (27%), Positives = 107/301 (35%), Gaps = 61/301 (20%)

Query: 298 TPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTP 357
           TP  P    A  S P  PKGL    PP          P L     P+  SP +  SP + 
Sbjct: 262 TPRAP----AHPSQP-KPKGLQALRPPQVTPPRKDAAPAL----GPLSSSPLATPSP-SG 311

Query: 358 LEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPP 417
            +   +P  +N       A   P+TLP   P    L      A    SA P+L + P PP
Sbjct: 312 TKARPVPPPDNA------ATPLPATLPPSPP----LATPLPLAPPSPSAPPSLQTLPSPP 361

Query: 418 ST------LYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRP----------------- 454
           +T         T  P   P S  T P P+ +  SLT  SL+ P                 
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIP-PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420

Query: 455 PPYDAVHS--------GSLSRSSPSVPHSTP--RPVSQDGAKMVNAAVNTYGAAPGGSRS 504
           P   A HS           S +SPS P STP   P  Q    +  +       +P  S  
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480

Query: 505 RTPTS--PLEELTSLFSSG-----RSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPK 557
            +P +  PL+ L+SL S        SL+      + S  P    T    + +   E LP 
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540

Query: 558 L 558
           L
Sbjct: 541 L 541



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 71/316 (22%), Positives = 105/316 (33%), Gaps = 49/316 (15%)

Query: 327 PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS---YMKQPAGASPSTL 383
           P LL+ RPP    PP PV           TP  +  L     V      ++  G   +T+
Sbjct: 22  PGLLTPRPPGSPRPPPPV-----------TPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 384 PSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSM- 442
           P   P          ++  PAS  PA                    P + +TSP PVS  
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRG-------------ERAPPAKNTSPGPVSSP 117

Query: 443 GRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGS 502
           GR+       RP P      G    +  +V         +  A    A  +T G  PG  
Sbjct: 118 GRA---SGTTRPGPLG--QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG-- 170

Query: 503 RSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKE 562
              TP+  +   +    +   L R + S  R + P E   + +   S  +   P    + 
Sbjct: 171 ---TPSPAMARRSRAAGTEVGLPRPAPSA-RPRPPTEGPRKSVSSASEHSTTEPSPAARR 226

Query: 563 RGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSAS 622
           R   G    R   ++     +  TP+ +      S   T  A  H S+PK          
Sbjct: 227 RPSAGGGLQRPASRSL---SSSATPLSSPARSGPSARGTPRAPAHPSQPK-------PKG 276

Query: 623 TSGVPPPSVTPLRQSS 638
              + PP VTP R+ +
Sbjct: 277 LQALRPPQVTPPRKDA 292


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 96/395 (24%), Positives = 124/395 (31%), Gaps = 86/395 (21%)

Query: 103 QDRLPHPCSSGF--SVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSS 160
           +  LP P S     S+  +SL+  G +D        R   P      S +    +++ SS
Sbjct: 93  EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVE----NDSDSS 148

Query: 161 TAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRT 220
           +  S+    P        P P         PP    R P          T    H P   
Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQ--------PPDSTPRQPEASFEPHPSVTPTGYHAPME- 199

Query: 221 SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLG 280
             P  S + Q  +P G P     +Y    G +L                    P     G
Sbjct: 200 --PPTSRMFQ--APPGAPPPHPQLYPGGTGGVLSG------------------PPMGPKG 237

Query: 281 QDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFP---NLLSHRPPLL 337
             A       +   Q   PT P    +  +   PP       PP  P     L   PP  
Sbjct: 238 GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK-----PPTTPVGGGNLPSAPPPA 292

Query: 338 VFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKL---- 393
            FP    H +PN    P        L  L N S      GA P  LP H+P    +    
Sbjct: 293 NFP----HVTPNLPPPPA-------LRPLNNASASPPGLGAQP--LPGHLPSPHAMGQGM 339

Query: 394 -------EKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSL 446
                  EK    A  P S  PA SS+P PP           +P S S+S S  +   S 
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR---------FPYSSSSSSSAAASSSSS 390

Query: 447 TPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVS 481
           +  S   P P         S++ PS PHS P P S
Sbjct: 391 SSSSSASPFP--------ASQALPSYPHSFPPPTS 417



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 110/451 (24%), Positives = 152/451 (33%), Gaps = 96/451 (21%)

Query: 140 PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSD---EYSKKIPPPKPK 196
           P  P R P +  S+SS   SS+++S S        +SA P P S     Y    PPP   
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSS--------SSASPFPASQALPSYPHSFPPP--- 415

Query: 197 RNPNTQLSTSFDETYIKKHGPRRT--SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILR 254
               T LS S          P+ T  SLP  +  SQ   P        P Y  ++ N   
Sbjct: 416 ----TSLSVS-------NQPPKYTQPSLPSQAVWSQGPPPP-------PPYGRLLANSNA 457

Query: 255 D---FRKEDDDQSEAV--------YEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPD 303
               F      QS A         + + +        Q  +    HH  S     P  P 
Sbjct: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG----PPPP- 512

Query: 304 LDFAKASVPCPPKGLLCDIPPPF---PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
                 + P P +G       P+   P+L S RP    +PP P H  P   +   +    
Sbjct: 513 -----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP----YPPGPAHLPPPHSQVSYSQAGP 563

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVP-GHAKLEKEQAAALGPASATPALSSSPPPPST 419
              PV  +       + +S ST     P  H    +    A  P    P +++S    ST
Sbjct: 564 NGPPVSSS-------SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLST 616

Query: 420 L----------YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSS 469
           +          Y+T SP G P     +PSP +            PP Y      S    +
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGA-------YKTATPPGYKPGSPPSFRTGT 669

Query: 470 PSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSS 529
           P     T  P      K  +  V   G  P    S  P+ P        +SG  L    S
Sbjct: 670 PPGYRGTSPPAGPGTFKPGSPTVGP-GPLPPAGPSGLPSLPPPPAAP--ASGPPL----S 722

Query: 530 SGRRSKEPAEK-STEELKV-RSHSTEPLPKL 558
           + +  +EPAE+  T E  V  + S  P PK+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSPPPKV 753



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 39/137 (28%), Positives = 47/137 (34%), Gaps = 13/137 (9%)

Query: 107 PHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPK----RDPSTKLSTSSETVSSTA 162
           P   SS  S  S S  S   +    S G +  P P P        S  LST   TV+S+ 
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625

Query: 163 ASKSGKTPERTEASAKPRPHSDEYSKKIPPP-KPKRNPNTQLSTSFDETYIKKHGPRRTS 221
           A     +P       K  P    Y    PP  KP   P+ +  T          G R TS
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT--------PPGYRGTS 677

Query: 222 LPRDSSLSQMGSPAGDP 238
            P      + GSP   P
Sbjct: 678 PPAGPGTFKPGSPTVGP 694



 Score = 30.0 bits (66), Expect = 7.0
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 15/96 (15%)

Query: 100 PAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVS 159
           PAP  R P+  SS  S  + S          SS  S   P P  +  PS   S       
Sbjct: 367 PAPPMRFPYSSSSSSSAAASS--------SSSSSSSSASPFPASQALPSYPHSFP----P 414

Query: 160 STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKP 195
            T+ S S + P+ T+ S    P    +S+  PPP P
Sbjct: 415 PTSLSVSNQPPKYTQPSL---PSQAVWSQGPPPPPP 447


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 96/395 (24%), Positives = 124/395 (31%), Gaps = 86/395 (21%)

Query: 103 QDRLPHPCSSGF--SVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSS 160
           +  LP P S     S+  +SL+  G +D        R   P      S +    +++ SS
Sbjct: 93  EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVE----NDSDSS 148

Query: 161 TAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRT 220
           +  S+    P        P P         PP    R P          T    H P   
Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQ--------PPDSTPRQPEASFEPHPSVTPTGYHAPME- 199

Query: 221 SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLG 280
             P  S + Q  +P G P     +Y    G +L                    P     G
Sbjct: 200 --PPTSRMFQ--APPGAPPPHPQLYPGGTGGVLSG------------------PPMGPKG 237

Query: 281 QDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFP---NLLSHRPPLL 337
             A       +   Q   PT P    +  +   PP       PP  P     L   PP  
Sbjct: 238 GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK-----PPTTPVGGGNLPSAPPPA 292

Query: 338 VFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKL---- 393
            FP    H +PN    P        L  L N S      GA P  LP H+P    +    
Sbjct: 293 NFP----HVTPNLPPPPA-------LRPLNNASASPPGLGAQP--LPGHLPSPHAMGQGM 339

Query: 394 -------EKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSL 446
                  EK    A  P S  PA SS+P PP           +P S S+S S  +   S 
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR---------FPYSSSSSSSAAASSSSS 390

Query: 447 TPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVS 481
           +  S   P P         S++ PS PHS P P S
Sbjct: 391 SSSSSASPFP--------ASQALPSYPHSFPPPTS 417



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 110/451 (24%), Positives = 152/451 (33%), Gaps = 96/451 (21%)

Query: 140 PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSD---EYSKKIPPPKPK 196
           P  P R P +  S+SS   SS+++S S        +SA P P S     Y    PPP   
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSS--------SSASPFPASQALPSYPHSFPPP--- 415

Query: 197 RNPNTQLSTSFDETYIKKHGPRRT--SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILR 254
               T LS S          P+ T  SLP  +  SQ   P        P Y  ++ N   
Sbjct: 416 ----TSLSVS-------NQPPKYTQPSLPSQAVWSQGPPPP-------PPYGRLLANSNA 457

Query: 255 D---FRKEDDDQSEAV--------YEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPD 303
               F      QS A         + + +        Q  +    HH  S     P  P 
Sbjct: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG----PPPP- 512

Query: 304 LDFAKASVPCPPKGLLCDIPPPF---PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
                 + P P +G       P+   P+L S RP    +PP P H  P   +   +    
Sbjct: 513 -----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP----YPPGPAHLPPPHSQVSYSQAGP 563

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVP-GHAKLEKEQAAALGPASATPALSSSPPPPST 419
              PV  +       + +S ST     P  H    +    A  P    P +++S    ST
Sbjct: 564 NGPPVSSS-------SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLST 616

Query: 420 L----------YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSS 469
           +          Y+T SP G P     +PSP +            PP Y      S    +
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGA-------YKTATPPGYKPGSPPSFRTGT 669

Query: 470 PSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSS 529
           P     T  P      K  +  V   G  P    S  P+ P        +SG  L    S
Sbjct: 670 PPGYRGTSPPAGPGTFKPGSPTVGP-GPLPPAGPSGLPSLPPPPAAP--ASGPPL----S 722

Query: 530 SGRRSKEPAEK-STEELKV-RSHSTEPLPKL 558
           + +  +EPAE+  T E  V  + S  P PK+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSPPPKV 753



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 39/137 (28%), Positives = 47/137 (34%), Gaps = 13/137 (9%)

Query: 107 PHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPK----RDPSTKLSTSSETVSSTA 162
           P   SS  S  S S  S   +    S G +  P P P        S  LST   TV+S+ 
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625

Query: 163 ASKSGKTPERTEASAKPRPHSDEYSKKIPPP-KPKRNPNTQLSTSFDETYIKKHGPRRTS 221
           A     +P       K  P    Y    PP  KP   P+ +  T          G R TS
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT--------PPGYRGTS 677

Query: 222 LPRDSSLSQMGSPAGDP 238
            P      + GSP   P
Sbjct: 678 PPAGPGTFKPGSPTVGP 694



 Score = 30.0 bits (66), Expect = 7.0
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 15/96 (15%)

Query: 100 PAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVS 159
           PAP  R P+  SS  S  + S          SS  S   P P  +  PS   S       
Sbjct: 367 PAPPMRFPYSSSSSSSAAASS--------SSSSSSSSASPFPASQALPSYPHSFP----P 414

Query: 160 STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKP 195
            T+ S S + P+ T+ S    P    +S+  PPP P
Sbjct: 415 PTSLSVSNQPPKYTQPSL---PSQAVWSQGPPPPPP 447


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 79/291 (27%), Positives = 116/291 (39%), Gaps = 37/291 (12%)

Query: 372  MKQPAGASPSTLPS-----HVPG--HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQ 424
            MKQP  A+  ++       H+PG  ++       +  GP   TPA S SP    T   T 
Sbjct: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA-SKSPSEGQTA--TT 2269

Query: 425  SPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP--RPVSQ 482
            SP G   S  +  SPV+   S    S K P       SGS   S+PS P   P  RP+  
Sbjct: 2270 SPRGAKPSVKSELSPVARQTSQIGGSSKAPS-----RSGSRD-STPSRPAQQPLSRPIQS 2323

Query: 483  DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRR-SKEPAEKS 541
             G   ++   N  G +P    S+ P +      S  SSG   +  +S GR+ S++   K 
Sbjct: 2324 PGRNSISPGRN--GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381

Query: 542  TEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPT 601
            T      S +   +P+ ++  +G +  ++     K  E      T    S   R S  P 
Sbjct: 2382 TG----LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR-SERPV 2436

Query: 602  LLAGN----HSSEPKVSCKLGRSASTSGVPPPS--VTPLRQSSDLQQSQVP 646
            L+  +     +  P +  KL  SAS   + P S   +P R      Q+Q P
Sbjct: 2437 LVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTR-----SQAQTP 2482


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 79/291 (27%), Positives = 116/291 (39%), Gaps = 37/291 (12%)

Query: 372  MKQPAGASPSTLPS-----HVPG--HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQ 424
            MKQP  A+  ++       H+PG  ++       +  GP   TPA S SP    T   T 
Sbjct: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA-SKSPSEGQTA--TT 2269

Query: 425  SPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP--RPVSQ 482
            SP G   S  +  SPV+   S    S K P       SGS   S+PS P   P  RP+  
Sbjct: 2270 SPRGAKPSVKSELSPVARQTSQIGGSSKAPS-----RSGSRD-STPSRPAQQPLSRPIQS 2323

Query: 483  DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRR-SKEPAEKS 541
             G   ++   N  G +P    S+ P +      S  SSG   +  +S GR+ S++   K 
Sbjct: 2324 PGRNSISPGRN--GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381

Query: 542  TEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPT 601
            T      S +   +P+ ++  +G +  ++     K  E      T    S   R S  P 
Sbjct: 2382 TG----LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR-SERPV 2436

Query: 602  LLAGN----HSSEPKVSCKLGRSASTSGVPPPS--VTPLRQSSDLQQSQVP 646
            L+  +     +  P +  KL  SAS   + P S   +P R      Q+Q P
Sbjct: 2437 LVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTR-----SQAQTP 2482


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 79/291 (27%), Positives = 116/291 (39%), Gaps = 37/291 (12%)

Query: 372  MKQPAGASPSTLPS-----HVPG--HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQ 424
            MKQP  A+  ++       H+PG  ++       +  GP   TPA S SP    T   T 
Sbjct: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA-SKSPSEGQTA--TT 2269

Query: 425  SPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP--RPVSQ 482
            SP G   S  +  SPV+   S    S K P       SGS   S+PS P   P  RP+  
Sbjct: 2270 SPRGAKPSVKSELSPVARQTSQIGGSSKAPS-----RSGSRD-STPSRPAQQPLSRPIQS 2323

Query: 483  DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRR-SKEPAEKS 541
             G   ++   N  G +P    S+ P +      S  SSG   +  +S GR+ S++   K 
Sbjct: 2324 PGRNSISPGRN--GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381

Query: 542  TEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPT 601
            T      S +   +P+ ++  +G +  ++     K  E      T    S   R S  P 
Sbjct: 2382 TG----LSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDR-SERPV 2436

Query: 602  LLAGN----HSSEPKVSCKLGRSASTSGVPPPS--VTPLRQSSDLQQSQVP 646
            L+  +     +  P +  KL  SAS   + P S   +P R      Q+Q P
Sbjct: 2437 LVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTR-----SQAQTP 2482


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 53/184 (28%), Positives = 69/184 (37%), Gaps = 29/184 (15%)

Query: 311 VPCPPKGL-----LCDIPPPFPNLLSHRPPLLV-----FPPAPVHCSPNSDESPLTPLEV 360
           VP PP  L      C  PPP P  LS  P ++      FPP P    P  +  PL P+  
Sbjct: 833 VPVPPPTLPKQQSFCAKPPPSP--LSPVPSVVKQIASQFPPPPT--PPAMESQPLKPVPA 888

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420
              P  ++   +K      PS++P   P       E +    P   +P  +  PPPP T 
Sbjct: 889 NVAP--QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA 946

Query: 421 YRTQSPHGYP-KSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRP 479
             T    G P K  S + SP            K+PPP       S  +SS    H  P+ 
Sbjct: 947 SPTPDKSGSPGKKTSKTSSPGG----------KKPPP--TPQRNSSIKSSSGAEHPEPKR 994

Query: 480 VSQD 483
            S D
Sbjct: 995 PSVD 998



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 80/347 (23%), Positives = 125/347 (36%), Gaps = 74/347 (21%)

Query: 139  PPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRN 198
            PPP P   P+          +S    KSG   ++T  ++ P         K PPP P+RN
Sbjct: 928  PPPPPSPVPAPP--PPPPPTASPTPDKSGSPGKKTSKTSSP-------GGKKPPPTPQRN 978

Query: 199  PNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPA--GDPEEE---------EPVYIE 247
             + + S+  +        P+R S+  DS +S+   PA  G P +E         +P  + 
Sbjct: 979  SSIKSSSGAEHP-----EPKRPSV--DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031

Query: 248  MVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFA 307
            + G  L    ++    ++A       P+    G+D+  +F      S    P        
Sbjct: 1032 LSGVNLPGVLQQGCVSAKA-------PVLSGRGKDSVVEFPSPPSDSDFPPPP------P 1078

Query: 308  KASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNS-------------DESP 354
            +  +P PP     +IP  F    S  P + V  P P   S  S             D + 
Sbjct: 1079 ETELPLPP----IEIPAVFSGNTS--PKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTR 1132

Query: 355  LTPLEVTKLPVLENV----------SYMKQP---AGASPSTLPSHVPGHAKLEKEQAAAL 401
            LT  E+++ P +  V          S   QP   A  + +     +  H  L    + A 
Sbjct: 1133 LTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRA- 1191

Query: 402  GPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTP 448
               +AT    + PPPP  L   Q   GY  SH +  + +  G    P
Sbjct: 1192 -EPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAP 1237



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 69/311 (22%), Positives = 98/311 (31%), Gaps = 56/311 (18%)

Query: 298 TPTVPDLDFAKASVPCPPKGLLCDIPPP---------------------FPNLLSHRPPL 336
           TP V      K  +  PP G++   PPP                      P   +  PPL
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747

Query: 337 LVF-------------PPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTL 383
            +              PP P   +P   ++P  PL     P             A P+  
Sbjct: 748 KIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPT 807

Query: 384 PSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMG 443
           P  VP   K     A+ + P+  TP +   P PP TL + QS    P     SP P  + 
Sbjct: 808 PP-VPPAKKQPAFPASYIPPSPPTPPV---PVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863

Query: 444 RSLTPLSLKRPP------PYDAVHSGSLSRSSPSV-------PHSTPRPVSQDGAKMVNA 490
           +  +       P      P   V +    +S P+V       P S P P S D       
Sbjct: 864 QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP-SPDFPPPPPE 922

Query: 491 AVNTYGAAPGGSRSRTPTSPLEELT----SLFSSGRSLLRKSSSGRRSKEPAEKSTEELK 546
           +   +   P       P  P    +       S G+   + SS G +   P  +    +K
Sbjct: 923 SSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIK 982

Query: 547 VRSHSTEPLPK 557
             S +  P PK
Sbjct: 983 SSSGAEHPEPK 993



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 51/208 (24%), Positives = 74/208 (35%), Gaps = 31/208 (14%)

Query: 309 ASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLEN 368
           AS P PP       PPP P      PP    PP P   +P++  +    ++ + +  L+N
Sbjct: 621 ASQPSPPLP-----PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675

Query: 369 VSYMKQPAGA--SPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSP 426
            S   Q +GA   P T P            Q+ ++ P    P     PPPP        P
Sbjct: 676 AS---QHSGALFKPPTPP----------VMQSQSVKPQILVPPNGVVPPPP-----PPPP 717

Query: 427 HGYPKSHSTSPSPVSMGRSLTPLSLKRPP--PYDAVHSGSLSRSSPSVPHSTPRPVSQDG 484
              P S      P     SL   S   PP   +   H   ++  +P  P   P P+    
Sbjct: 718 PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777

Query: 485 AK----MVNAAVNTYGAAPGGSRSRTPT 508
                  + A  +T   AP  +++  PT
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPT 805


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 117/520 (22%), Positives = 170/520 (32%), Gaps = 72/520 (13%)

Query: 47  DRLRNETNLAYLKEKNEKRRRQEEAIKRIGGEVG--RGHEGSYVGKHFRMGFMTMPAPQD 104
           D    ET L+ LKEK +KR  +EE    + G+    R H+ S  G       +    P  
Sbjct: 40  DPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPAS 99

Query: 105 RLPHPCSSGFSVRSQS----LHSVGGTDDDSS-CGSRRQPPPKPKRDPSTKLSTSSETVS 159
            +P P S    + SQS    L+    +   SS  G+     P   R+  T   +S+  +S
Sbjct: 100 FVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGIS 159

Query: 160 -------------STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
                        S+ AS   +TPER     +        S   P    K    +Q   +
Sbjct: 160 QLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADK---ESQGEKA 216

Query: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEA 266
            D T  KK      S P  S   +           E + +     +      ED D  + 
Sbjct: 217 ADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKK 276

Query: 267 VYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFA--KASVPCPPKGLLCDIPP 324
              +      +D     K D   +S +    T T P   F    A+   PP  LL     
Sbjct: 277 ASLQWFNQALED-----KSDAASNSVTETPPT-TQPSFTFTLPAAATASPPTSLLAPSTN 330

Query: 325 PFPNLLS--HRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPST 382
           P    L     PP L  PP P      + E+   P   + LP          P G S S 
Sbjct: 331 PLLESLKKMQTPPSL--PPCPESAGAATTEALSPPKTPSLLP----------PLGLSQS- 377

Query: 383 LPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLY-RTQSPHGYPKSHSTSPSPVS 441
                              GP    P+ S    PP+TL     +P   P + + +P  + 
Sbjct: 378 -------------------GPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQ 418

Query: 442 MGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGG 501
              +  P +   P P  A     L  +  + P S   P +   + M          AP  
Sbjct: 419 AETATKPQATSAPSP--APKQSFLFGTQNTSPSSPAAPAASSASPMFKPIF----TAPPK 472

Query: 502 SRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKS 541
           S    PT P   +T+   S  SL   +S+   + +P   S
Sbjct: 473 SEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS 512


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 82/293 (27%), Positives = 112/293 (38%), Gaps = 45/293 (15%)

Query: 370 SYMKQPA--GASPSTLP-------SHVPGHAKLEKEQAAALGPASATPAL---SSSPPPP 417
           S+ + PA  G S S  P       S  P   +            S TPA    S S  P 
Sbjct: 562 SHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPA 621

Query: 418 STLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP 477
               RT+SP    +S S SP+  S GRS +    +R             RS    P    
Sbjct: 622 RRRSRTRSPVRR-RSRSRSPARRS-GRSRSRTPARR------------GRSRSRTPARRG 667

Query: 478 RPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRS----LLRKSSSGRR 533
           R  S+  A+    + +   A  G SRSRTP        SL   GRS      R+  SG  
Sbjct: 668 RSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS 727

Query: 534 SKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKA-----QEWDGTPGTPV 588
           S+   +  T + + RS+S+  + K     R     SS R   K+     +   G+   P 
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787

Query: 589 VTSRLGRCSVSPTLLAGNHSSEPKVSCKL--GRSASTSGVPP--PSVTPLRQS 637
             S+      +P   + + SS+PK   +    RS S+S  PP   S TP RQS
Sbjct: 788 QKSQ------TPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 87/376 (23%), Positives = 127/376 (33%), Gaps = 44/376 (11%)

Query: 298  TPTVPDLDFAKASVPCPPKGLLCD---IPPPFPNL-LSHRPPL------LVFP-----PA 342
            TPT P ++ A A  P     L       PP   N   S R P       LV P      A
Sbjct: 2289 TPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATA 2348

Query: 343  PVHCSPNSDESPLTPLEVTKL---PVLENVS----------YMKQPAGASPSTL------ 383
            PV+ + +   + L P  +T     P L   +          Y +     SP  L      
Sbjct: 2349 PVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSR 2408

Query: 384  -PSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHS---TSPSP 439
             P   P  +++  E+A +           S  PP     R+  P  +           +P
Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP 2468

Query: 440  VSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHS-TPRPVSQDGAKMVNAAVNTYGAA 498
            V+  +SL+  ++         H+G LS  +P VPHS    P +  GA+  +A      A 
Sbjct: 2469 VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSA----LAAL 2524

Query: 499  PGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKL 558
                  R+ +S     +S  SS  S    SSSG  S +    S       +    P P  
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP 2584

Query: 559  DNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLG 618
              KE    G      P K +    +  +   +S     S S +  + + SS    S    
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 619  RSASTSGVPP-PSVTP 633
             S+S S   P P   P
Sbjct: 2645 SSSSPSPAKPGPQALP 2660



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 121/555 (21%), Positives = 179/555 (32%), Gaps = 97/555 (17%)

Query: 53  TNLAYLKEKNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSS 112
           T    L E NEK+    E ++   G      +GS      R      PAP+   P+    
Sbjct: 119 TETHQLAELNEKKN---ERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSL-- 173

Query: 113 GFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPER 172
              VR  S          S   + +Q   K K+D   +  +SS       +SK  K   R
Sbjct: 174 ---VRESS---------SSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK--HR 219

Query: 173 TEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMG 232
           +E+ +K R H      + P PK KR               KK    R++ P   S     
Sbjct: 220 SESESKKRKH------RSPTPKSKRKSKD-----------KKRKRSRSTTPAPKSRRAHR 262

Query: 233 SPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSC 292
           S + D             +  R         + A+      P     G+      +  + 
Sbjct: 263 STSADSASSSDT------SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTT 316

Query: 293 SSQCATPTVPDLDFAKASVPCPPKGL-----LCDIPPPFPNLLSHRPPLLVFPPAPVHCS 347
           S+Q   P+ P+    + S P   K           P P P   S  P     PPAP    
Sbjct: 317 STQ--RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPE----PPAP---- 366

Query: 348 PNSDESPLTPLEVTKLPVLENVSYMKQPAGASP-STLPSHVPGHAKLEKEQAAALGPASA 406
                   TPL      + E      QP   +P S  P + P  A   ++++    P   
Sbjct: 367 --------TPL------LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL 412

Query: 407 TPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGR---SLTPLSLKRPPPYDAVHSG 463
             + SS   PPS      S H      S  P+P        S +P S  R        S 
Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNR--------SH 464

Query: 464 SLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAP---GGSRSRTPTSPLEELTSLFSS 520
             ++   S  H+  R + +  +        +    P   G SRSR+P          +  
Sbjct: 465 GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524

Query: 521 GRSLLRKSS---------SGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKER--GHHGAS 569
            RS  R+           S  R+ +   +S    + RSHS  P  +  ++ R     G S
Sbjct: 525 SRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRS 584

Query: 570 SSREPVKAQEWDGTP 584
            SR P + +    TP
Sbjct: 585 RSRTPARRRSRSRTP 599



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 71/283 (25%), Positives = 106/283 (37%), Gaps = 28/283 (9%)

Query: 370 SYMKQPAGASPSTLPSHVPGHAK--LEKEQAAALGPASATPALSSSPPPPSTLYRTQSPH 427
           S  +  + +SP    S +       L   ++ A    S   +LS S P P    ++Q+P 
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQ--KSQTPP 794

Query: 428 GYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKM 487
              +S S+ P   S        S   PPP     + S    S S PH   +  +      
Sbjct: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS 854

Query: 488 VNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKV 547
           + +      +     RS   +SP  EL S     R+  R S SG  S    + ST   + 
Sbjct: 855 ITSPQANEQSVTPQRRSCFESSPDPELKS-----RTPSRHSCSG-SSPPRVKSSTPPRQS 908

Query: 548 RSHSTEPLPK----LDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLL 603
            S S+ P PK    +  ++R H G+SS   P  ++    T  TP  +  +  CS   + L
Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSS---PSPSRVTSRT--TPRRSRSVSPCSNVESRL 963

Query: 604 AGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVP 646
              +S         G S+  + V P   TP RQS     S  P
Sbjct: 964 LPRYSHS-------GSSSPDTKVKPE--TPPRQSHSGSISPYP 997



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 23/288 (7%)

Query: 338  VFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQ 397
            V P A       SD SP +  + T+ P+ +       P   S S L    P  ++     
Sbjct: 1547 VKPSASPQERSESDSSPDSKAK-TRTPLRQRSRSGSSPEVDSKSRLS---PRRSRSGSSP 1602

Query: 398  AAALGPASATPALS---SSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRP 454
                 P +A  A S   SSP P +   R         S S    P   G S T  S + P
Sbjct: 1603 EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662

Query: 455  PPYDAVHSGSLSRSSPSVPHSTP--RPVSQDGAKMVNAA--VNTYGAAPGGSRSRTPTSP 510
            P       GS S   P     TP  R  S+   ++   A       +A     +R+ T P
Sbjct: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722

Query: 511  LEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASS 570
                +   SS      KS S RR +  +   T+    R  S  P P+   + R    + S
Sbjct: 1723 RHRRSPSVSSPEP-AEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR----SRS 1777

Query: 571  SREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLL-------AGNHSSEP 611
             RE  +        G+   TSR  + S S + +       +G HS  P
Sbjct: 1778 RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 51/212 (24%), Positives = 77/212 (36%), Gaps = 21/212 (9%)

Query: 347  SPNSDESPLTPLEVTKLPVLENVSYMKQPA-------GASPSTLPSHVPGHAKLEKEQAA 399
            S +S  S  +  E + LPV   V+  + P+              P   P   K     ++
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611

Query: 400  ALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSL--TPLSLKRPPPY 457
            +   +S++ + SSS    S+   + S      S S+SPSP   G      P S K+PPP 
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP- 2670

Query: 458  DAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSL 517
                 G     SP  P  + R    D   +  + V     +P  S     +S  E  +  
Sbjct: 2671 -----GERRSRSPRKPIDSLR----DSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721

Query: 518  FSSGRSLLRKSSSGRRSKEPAEKSTEELKVRS 549
               G S  R  S  RR + P+ +       RS
Sbjct: 2722 GQRGDS--RSPSHKRRRETPSPRPMRHRSSRS 2751



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 67/291 (23%), Positives = 103/291 (35%), Gaps = 49/291 (16%)

Query: 347  SPNSDESPLTP-----LEVTKLPVLENVSYMKQP-AGASPSTLPSHVPGHAKLEKEQAAA 400
            SP ++E  +TP      E +  P L++ +  +   +G+SP  + S  P            
Sbjct: 857  SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ--------- 907

Query: 401  LGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAV 460
                  +P+ SSSP P   +    SP     S S+SPSP  +    TP   +   P   V
Sbjct: 908  ------SPSRSSSPQPK--VKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNV 959

Query: 461  ---------HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPL 511
                     HSGS S  +   P + PR                    P  S S++P    
Sbjct: 960  ESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019

Query: 512  EELTSLFSSGRSLLRKSSSGRRSKEPAEK----STEELK--------VRSHSTEPLPKLD 559
            +   SL  S    L   +  + S  P E     S+ +LK         RS ++ P  +  
Sbjct: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079

Query: 560  NKERGHHGASSSREPVKAQEWDGTPGTPV-----VTSRLGRCSVSPTLLAG 605
            + E     + S   P   +    +P T +     +    G  S SP L +G
Sbjct: 1080 HSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSG 1130



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 129/601 (21%), Positives = 209/601 (34%), Gaps = 95/601 (15%)

Query: 100  PAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSC-----------GSRRQPPPKPK-RDP 147
            PAP+  LP    SG S + +     G +  +SS            GSR  P PK K R P
Sbjct: 1627 PAPR-ALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685

Query: 148  STKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSF 207
              + S+ S   S     K+  +     AS+ P   S        PP+ +R+P    S S 
Sbjct: 1686 PRRRSSRS---SPELTRKARLSRRSRSASSSPETRSR------TPPRHRRSP----SVSS 1732

Query: 208  DETYIKKHGPRR---TSLPRDSSLSQMG-SPAGDPEEEEPVYIEMVGNILRDFRKEDDDQ 263
             E   K    RR    S PR  + S+ G SP+  P   +           R  R+ D   
Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSG 1792

Query: 264  S--EAVYEEMKYPIFDDLGQDAKCDFDHHSCS---------------SQCATPTVPDLDF 306
            S         +      + +  +    +HS S                +  TP       
Sbjct: 1793 SSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRS 1852

Query: 307  AKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVL 366
               + P P K       P        R PL+         S     S  +P+   +    
Sbjct: 1853 RSRTSPAPWKRSRSRASPATHRRSRSRTPLI---------SRRRSRSRTSPVSRRRSRSR 1903

Query: 367  ENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSP 426
             +V+  +  + ASP +          + + ++ +  P +   + S +PP      R+++P
Sbjct: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP 1963

Query: 427  HGYPKSHSTSPSPVSMGRS---LTPLSLKRPPPYDAVHSGSLSRSSPSV---PHSTPRPV 480
                +   +  SP++  RS    +P++ +R          S SR+SP       S   PV
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSPVTRRR----------SRSRTSPVTRRRSRSRTSPV 2013

Query: 481  SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTS-----LFSSGRSLLRKSSSGRRS- 534
            ++  ++       T  A    SRSRTP  P +   S     +    RS   +++ G+RS 
Sbjct: 2014 TRRRSRS-----RTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSL 2068

Query: 535  --KEPA---EKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVV 589
                PA     ++     RS S  P        R H G+ +    + +          + 
Sbjct: 2069 TRSPPAIRRRSASGSSSDRSRSATP-----PATRNHSGSRTPPVALNSSRMSCFSRPSMS 2123

Query: 590  TSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVPSSL 649
             + L RC  SP +L    SS   +S       S    P P + P  Q + + ++   S +
Sbjct: 2124 PTPLDRCR-SPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRI-PDHQRTSVPENHAQSRI 2181

Query: 650  A 650
            A
Sbjct: 2182 A 2182



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 63/261 (24%), Positives = 93/261 (35%), Gaps = 39/261 (14%)

Query: 325  PFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLP 384
            P P+  S +   L+    PV  S +     +     T     ++   +  PA   P +  
Sbjct: 2450 PVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA---TTTSSAGDHNGMLSVPAPGVPHSDV 2506

Query: 385  SHVPGHAKLEKEQA-AALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMG 443
               P     ++  A AAL PA    + SSS    S+   + S      S  +S S  S G
Sbjct: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD-SEG 2565

Query: 444  RSLT---PLSLKR-----PPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTY 495
             SL     ++LKR     P P +AV  G              RP     AK    + ++ 
Sbjct: 2566 SSLPVQPEVALKRVPSPTPAPKEAVREG--------------RPPEPTPAKRKRRSSSSS 2611

Query: 496  GAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPL 555
             ++   S S + +S     +S  SS  S    SSS   S  PA+   + L   +   +P 
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSS--SSSSSSSSSPSPAKPGPQALPKPASPKKPP 2669

Query: 556  PKLDNKERGHHGASSSREPVK 576
            P          G   SR P K
Sbjct: 2670 P----------GERRSRSPRK 2680



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 34/129 (26%), Positives = 53/129 (41%), Gaps = 29/129 (22%)

Query: 137  RQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEAS------------------AK 178
            R P P P +      S+SS + SS+++S S  +   + +S                  AK
Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653

Query: 179  PRPHS--DEYSKKIPPPKPKRNPNTQL-------STSFDETYIKKHGPRRTSLPRD--SS 227
            P P +     S K PPP  +R+ + +        S S   + +++  P     PRD  SS
Sbjct: 2654 PGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSS 2713

Query: 228  LSQMGSPAG 236
             S+ GS  G
Sbjct: 2714 SSERGSRRG 2722



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 39/162 (24%), Positives = 61/162 (37%), Gaps = 17/162 (10%)

Query: 95   GFMTMPAPQDRLPH------PCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPS 148
            G +++PAP   +PH      P S+G    S         +  SS  S            S
Sbjct: 2492 GMLSVPAPG--VPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549

Query: 149  TKLSTSSETVSSTAASKSGKTPERTEASAK----PRPHSDEYSKKIPPPKP---KRNPNT 201
            +  S+SS + SS++ S+    P + E + K    P P   E  ++  PP+P   KR   +
Sbjct: 2550 S--SSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRS 2607

Query: 202  QLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEP 243
              S+S   +         +S    SS S   S +       P
Sbjct: 2608 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 42/183 (22%), Positives = 61/183 (33%), Gaps = 24/183 (13%)

Query: 454 PPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEE 513
           P PY  V   S SRS        P P  +   K  +    +  ++P   R ++       
Sbjct: 168 PKPYSLVRESSSSRS--------PTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHR 219

Query: 514 LTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSRE 573
                S   S  RK  S   + +   KS ++ + RS ST P PK     R     S+S  
Sbjct: 220 -----SESESKKRKHRSP--TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSS 272

Query: 574 PVKAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHS------SEPKVSCKLGRSASTSGVP 627
                           T+  GR   SP+  +G         SEP  +     S+  +   
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGR---SPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329

Query: 628 PPS 630
            PS
Sbjct: 330 QPS 332


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 59/229 (25%), Positives = 85/229 (37%), Gaps = 24/229 (10%)

Query: 323  PPPF---PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGAS 379
            PPP    P  L+H PPL    P P   +    + P++P  V   PV       K     +
Sbjct: 1195 PPPAEPPPTDLAHLPPL----PPPEGEARKPAKPPVSPKPVLTQPV------PKLQGSPT 1244

Query: 380  PSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSP 439
            P++    +PG    E ++A    P    P     PPPP+     ++  G P S S  PSP
Sbjct: 1245 PTSKKVPLPGPGSPEVKRAHGTPP----PVSPKPPPPPTAPKPVKAVAGLP-SGSAGPSP 1299

Query: 440  VSMGRSLTPLSLKRPPPYDAVHSGSLSRS-SPS-----VPHSTPRPVSQDGAKMVNAAVN 493
                    P +L +PP        S ++  SP      VP   PR  +   A        
Sbjct: 1300 APSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAP 1359

Query: 494  TYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKST 542
              GA+PG S  +        L +   +    +R+  +       AEKST
Sbjct: 1360 PEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKST 1408



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 38/127 (29%), Positives = 42/127 (33%), Gaps = 14/127 (11%)

Query: 385  SHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGR 444
            S   G  +L      A  P +    L   PPP     +   P   PK   T P P   G 
Sbjct: 1183 SEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQG- 1241

Query: 445  SLTPLSLKRPPPYDAVHSGSLSRSSPSV--PHSTPRPVSQDGAKMVNA--AVNTYGAAPG 500
            S TP S K P P            SP V   H TP PVS        A   V      P 
Sbjct: 1242 SPTPTSKKVPLP---------GPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPS 1292

Query: 501  GSRSRTP 507
            GS   +P
Sbjct: 1293 GSAGPSP 1299


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 75/310 (24%), Positives = 115/310 (37%), Gaps = 35/310 (11%)

Query: 139  PPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRN 198
            PPP     P     T   T S    +K  + PE   A+  P P         PPP P   
Sbjct: 800  PPPPSGATPPPIAPTGPPTASPPVPAK--EEPEELPAAPGPLPPPP------PPPPPVPG 851

Query: 199  PNTQLSTSF-DETYIKKHGPRRTSLPRDSSLSQMGSP--AGDPEEEEPVYIEMVGNILRD 255
            P T        E      GP   +L  D ++  + S     + EEEE    E       D
Sbjct: 852  PVTLPPPQLVPEGTPGGGGP--PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEED 909

Query: 256  FRKEDDDQSEAVYEEMKYPI-----FDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKAS 310
            F +E++D+ E   EE +        F++   + + + +      +     V DL+F  A 
Sbjct: 910  FEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAG 969

Query: 311  VPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS 370
                  G + +  PP P L    PP L  P +P    P  +  P   LEV +    E   
Sbjct: 970  ------GEVEEGAPPPPTL----PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEE--- 1016

Query: 371  YMKQPAGASPSTLPSHVPGHAKLEKE-QAAALGPASATPALSSSPPPPSTLYRTQSPHGY 429
              ++ A  +P+  P  +P   ++E+E ++ A GP      +   P  P TL   ++  G 
Sbjct: 1017 --ERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQE-LVEEEPSAPPTLLEEETEDGS 1073

Query: 430  PKSHSTSPSP 439
             K      +P
Sbjct: 1074 DKVQPPPETP 1083


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 137/606 (22%), Positives = 202/606 (33%), Gaps = 100/606 (16%)

Query: 106  LPHPCSSGFS--VRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAA 163
            LP P +SG S  +   +   + GT    + G R  P P     P+T         ++T  
Sbjct: 1331 LPTPATSGTSPTLPKSTNQELPGTTATQTTGPR--PTPASTTGPTTPQPGQPTRPTATET 1388

Query: 164  SKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLS---------TSFDETYIKK 214
            +++  T   TE +    PH+         P P   P T  S          S  ET +  
Sbjct: 1389 TQTRTT---TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPT 1445

Query: 215  HGPR-RTSLPRDSSLS-------QMGSPAGDPEEEE-----PVYIEMVGNILR----DFR 257
            H P   TSL   S+ +       QM + A +          P  ++  G+          
Sbjct: 1446 HVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPT 1505

Query: 258  KEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTV-PDLDFAKASVPCPPK 316
                 Q+ + +   K P        +     HH   +  +T T+ P+    +   P    
Sbjct: 1506 TSGTSQAHSSFSTNKTPT----SLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHT 1561

Query: 317  GLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPA 376
                   PP P   +H PP           SP S   P+T             S+ +   
Sbjct: 1562 NSATSSRPP-PPFTTHSPP--------TGSSPFSSTGPMTATSFKTTTTYPTPSHPQ--- 1609

Query: 377  GASPSTLPSHVPG----------HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSP 426
                +TLP+HVP           H  +    A     AS     + + PPP+TL  T S 
Sbjct: 1610 ----TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGST 1665

Query: 427  HGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLS-----RSSPSVPHSTPRPVS 481
            H  P    T     + G S    SL       ++HS + S      +S S  + TP P S
Sbjct: 1666 HTAPTMTLT-----TSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS 1720

Query: 482  QDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRK--SSSGRRSKEPAE 539
                 M    V T G     S+SR+  S  +  TSL S   S      +S+   S  P  
Sbjct: 1721 TGTPPM---TVTTSGT----SQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNH 1773

Query: 540  KSTEELKVRSHSTE------PLPKLDNKERGHHGASSSREPVKAQEWD-----GTPGTPV 588
             ST      +H+T       P P   +         SS  PV A  +       TP  P 
Sbjct: 1774 TSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPH 1833

Query: 589  VTSRLGRCSVSPTLLA-GNHSSEPKVSCKLGRSAS-----TSGVPPPSVTPLRQSSDLQQ 642
             T      S S +L+    H+       ++  SAS     T  +PPP+      S+    
Sbjct: 1834 TTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP 1893

Query: 643  SQVPSS 648
               P++
Sbjct: 1894 PMTPTT 1899



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 63/299 (21%), Positives = 109/299 (36%), Gaps = 63/299 (21%)

Query: 347  SPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASA 406
            SP+S+ +P +P   T+ P+L             P+TL S  P  +  E  +       + 
Sbjct: 1239 SPSSNHTPASP---TQTPLL-------------PATLTSSKPTASSGEPPRPT----TAV 1278

Query: 407  TPALSSSPPPPSTLYRTQSPHGYPK------SHSTSPSPVSMGRSLTPLSLKRPPPYDAV 460
            TP  +S  PP +TL  T +     +      + + SP+  S  +S T  ++  P P    
Sbjct: 1279 TPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTP---- 1334

Query: 461  HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS 520
               + S +SP++P ST + +          A  T G  P  + +  PT+P          
Sbjct: 1335 ---ATSGTSPTLPKSTNQELPG------TTATQTTGPRPTPASTTGPTTP---------- 1375

Query: 521  GRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEW 580
                      G+ ++  A ++T+      ++T   P   +          S  PV A  +
Sbjct: 1376 --------QPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSF 1427

Query: 581  DG-----TPGTPVVTSRLGRCSVSPTLLA-GNHSSEPKVSCKLGRSASTSGVPPPSVTP 633
                   TP  P  T        S +L+    H+       ++  SAS    P  ++ P
Sbjct: 1428 HATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPP 1486



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 75/334 (22%), Positives = 112/334 (33%), Gaps = 51/334 (15%)

Query: 322  IPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPS 381
            +P PF    +H PP           SP S   P+T             S+ +       +
Sbjct: 1962 LPTPFT---THSPP--------TGSSPFSSTGPMTATSFQTTTTYPTPSHPQ-------T 2003

Query: 382  TLPSHVPG----------HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYP- 430
            TLP+HVP           H  +          AS     + + PPP+TL  T S H  P 
Sbjct: 2004 TLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP 2063

Query: 431  ---------KSHS-----TSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHST 476
                     ++HS     T+ S      S  P +    PP   + +     SS + P ST
Sbjct: 2064 MTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVST 2123

Query: 477  PRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKE 536
               +S   +   +A        P    S   +SP    +S F S        SSG  S  
Sbjct: 2124 TNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSL 2183

Query: 537  PAEKSTEELKVRS-HSTEPLPKLDNKERGHHGAS-----SSREPVKAQEWDGTPGTPVVT 590
                +T  +       + P      +    H  S     S+  P+       TP + + +
Sbjct: 2184 STHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243

Query: 591  SRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTS 624
            S +   S +P   A  H++ P  S +   S STS
Sbjct: 2244 STIAFPS-TPRTTASTHTA-PAFSSQSTTSRSTS 2275



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 68/301 (22%), Positives = 108/301 (35%), Gaps = 73/301 (24%)

Query: 327  PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSH 386
            P   S RPP           SP + + P      T +     +S    P+ ++PST+ S+
Sbjct: 2095 PQNSSSRPP----------SSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSY 2144

Query: 387  VPGHAKLEKEQAAALGPASA------------------------TPALSSSP-----PPP 417
            VP      +  + ++G +S+                        T ++S+SP     P  
Sbjct: 2145 VPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAA 2204

Query: 418  STLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP 477
            ST  R   PH       T  SP ++  +L P+S     P  + H  S + + PS P +T 
Sbjct: 2205 STTIRATLPH-------TISSPFTLS-ALLPISTVTVSPTPSSHLASSTIAFPSTPRTT- 2255

Query: 478  RPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEP 537
                        A+ +T   AP  S   T +      T + +SG   L    +G  +   
Sbjct: 2256 ------------ASTHT---APAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPV 2300

Query: 538  AEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCS 597
               +T        +  P  +        HG++ +  PV +       GTP  TS  G CS
Sbjct: 2301 TNLTTRH---PGPTLSPTTRFLTSSLTAHGSTPASAPVSSL------GTPTPTSP-GVCS 2350

Query: 598  V 598
            V
Sbjct: 2351 V 2351



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 51/202 (25%), Positives = 67/202 (33%), Gaps = 45/202 (22%)

Query: 322  IPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPS 381
            +P PF    +H PP           +P S   P+T             S+         +
Sbjct: 1793 LPTPFT---THSPP--------TGTTPISSTGPVTATSFQTTTTYPTPSHPH-------T 1834

Query: 382  TLPSHVPG----------HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHG--- 428
            TLP+HVP           H  +          AS     + + PPP+T+  T S H    
Sbjct: 1835 TLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPP 1894

Query: 429  -YPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKM 487
              P +  TS SP S   + T  SL    PY          SS   P  TP   +    K 
Sbjct: 1895 MTPTTSGTSQSPSSFSTAKTSTSL----PYHT--------SSTHHPEVTPTSTTNITPKH 1942

Query: 488  VNAAVNTYGA-APGGSRSRTPT 508
             +    T  A     S SR PT
Sbjct: 1943 TSTGTRTPVAHTTSASSSRLPT 1964


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 129/560 (23%), Positives = 182/560 (32%), Gaps = 89/560 (15%)

Query: 99  MPAPQDRLPHPCSSGFSVRSQS----LHSVGGTDDDS-SCGSRRQPPPKPKRDPSTKLST 153
           +P PQ        SG S    S    + S G     S S    ++PPP P+R  S  L  
Sbjct: 452 VPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS--LHQ 509

Query: 154 SSETVSSTAASKSGKTPERTEASAKPRPHS---DEYSKKIP-PPKPKRNPNTQLSTSFDE 209
               V         K PER +    PRP +    E +   P PP P  +    LS     
Sbjct: 510 RGLAVPDGPLGLPPK-PERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSR 568

Query: 210 TYIKKHGPRRTSLPRDSSLSQMGSPA----------GDPEEEEPVYIEMVGNILRDFRKE 259
                  P RT  P     SQ G+P             P + +P   E V ++    R  
Sbjct: 569 R--PPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSL----RSP 622

Query: 260 DDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLL 319
               S ++               + C        S  + P +      +  +P  PK   
Sbjct: 623 GASVSSSL--------------TSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668

Query: 320 CDIPPPF-PNLLSHRPPLLVFP---PAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQP 375
              PPP  P   +   P L  P   P PV  +  S +SP TP   T L  L+    + + 
Sbjct: 669 PFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQ--TTLTPLQESPVISKD 726

Query: 376 AGASPSTLPSHVPGHAKLEKEQAAALGPASATPALS-----SSPPPPSTLYRTQSPHGYP 430
               PS  PS+ P     +K +     P+++  A       + PPPP             
Sbjct: 727 QSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP------------ 774

Query: 431 KSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNA 490
                 P+P     S+       PPP +A  S  ++   P+ P  +P  VS   A   ++
Sbjct: 775 ------PAPEEQDLSMADF----PPPEEAFFS--VASPEPAGPSGSPELVSSPAAS--SS 820

Query: 491 AVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSH 550
           +       P GS    P  P     S      + L +       KEP   S      R  
Sbjct: 821 SATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQ-------KEPVGCSKGGGPPRED 873

Query: 551 STEPL--PKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSPTLLAGNHS 608
              PL  P L    R     +    P  A      P  P+  +  GR S  P   +G H+
Sbjct: 874 VGAPLVTPSLLQMVRLRSVGAPGGAPTPALG-PSAPQKPLRRALSGRASPVPAPSSGLHA 932

Query: 609 SEPKVSCKLGRSASTSGVPP 628
           +    +C L  S   S   P
Sbjct: 933 AVRLKACSLAASEGLSSAQP 952



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 52/167 (31%), Positives = 70/167 (41%), Gaps = 45/167 (26%)

Query: 403 PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSM---------GRSLTPLSLKR 453
           P S+T + S  PPP        S  G P   ST+ +  ++         GRS++   LKR
Sbjct: 442 PESSTASNSVVPPPQGG-----SGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR 496

Query: 454 PPPYDAVHSGSLSRSSPSVPH---------------STPRPVSQDGAKMVNAA------V 492
           PPP     + SL +   +VP                  PRP +  G++   AA       
Sbjct: 497 PPP-PPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPA 555

Query: 493 NTY--GAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEP 537
           N++  G +PGGSR R P SP  E T   SSG S    S SG  +  P
Sbjct: 556 NSWVPGLSPGGSR-RPPRSP--ERTLSPSSGYS----SQSGTPTLPP 595



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 19/59 (32%), Positives = 25/59 (42%)

Query: 593 LGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVPSSLAN 651
           LGRCS+        HS+ P     LGR +S S   P S  P   S     SQ   ++ +
Sbjct: 369 LGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVS 427


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 76/258 (29%), Positives = 93/258 (36%), Gaps = 48/258 (18%)

Query: 322 IPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPS 381
           +PPPF       PPL   PP  +   P S   P+ P     LP    V     P    P 
Sbjct: 516 MPPPFVPYSQMPPPLPTMPPPVL---PPSLPPPVMP---PALPA--TVPPPGMPPPVMPP 567

Query: 382 TLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVS 441
           +LP+ VP         +A   P    P+LSS+ PPP        P   P   ST+P PV 
Sbjct: 568 SLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPP-----VLPP---PSLSSTAPPPV- 618

Query: 442 MGRSLTPLSLKRPPP----------------YDAVHSGSLSRSS--PSVPHST--PRPVS 481
               L PLS   PPP                   V   S S+SS  P  P     P PVS
Sbjct: 619 --MPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVS 676

Query: 482 QDGAKMVNAAVNTYGAAPGGS-RSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
              A           A P     S+ P S      S FSS + L      G  S  P++ 
Sbjct: 677 FGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL------GESSAAPSQP 730

Query: 541 ST--EELKVRSHSTEPLP 556
            T  +++ VRS    P P
Sbjct: 731 ITAVKDMPVRSGGLLPDP 748



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 55/244 (22%), Positives = 79/244 (32%), Gaps = 24/244 (9%)

Query: 331 SHRPPLLVFPPAPV---HCSP----NSDESPLTP----------LEVTKLPVLENVSYMK 373
           SH PP  V PP PV     SP    +S  +P  P            + +L  L+ +   +
Sbjct: 12  SHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71

Query: 374 QPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSH 433
                 P  LP   P             G     P     PP P+  Y+ Q  + +   H
Sbjct: 72  MQCVLQPHHLPP--PPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLH 129

Query: 434 STSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPS-VPHSTPRPVSQDGAKMVNAAV 492
                P      L P+ L+ PP    V  GS    S S +P   P P             
Sbjct: 130 HQRDGP----PGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP 185

Query: 493 NTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHST 552
               +      S++  +P    +S  SS +S L  S S   S + +     +   +S   
Sbjct: 186 PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL 245

Query: 553 EPLP 556
            P P
Sbjct: 246 APPP 249



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 59/213 (27%), Positives = 77/213 (36%), Gaps = 33/213 (15%)

Query: 299 PTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESP-LTP 357
           P +P   +     P PP      +PPP    LS++           H     D  P L P
Sbjct: 90  PVMPGGGYGDWQPPPPP------MPPPPGPALSYQKQQQYKHQMLHH---QRDGPPGLVP 140

Query: 358 LEVTKLPVLENV---SYM--KQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSS 412
           +E+   P    V   SYM   Q     P   PS+ P  +       A   P+ + P+ S 
Sbjct: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200

Query: 413 SPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGS--LSRSSP 470
             P PS          Y  S S+S S +S  +S  P S   P      HS S  L+   P
Sbjct: 201 LAPTPS----------YSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPP 250

Query: 471 SVPHSTPRPVSQD----GAKMVNAAVNTYGAAP 499
           S P      V Q+    GAK  N +     AAP
Sbjct: 251 SAPPGNKTTVQQEPLESGAK--NKSTEQQQAAP 281



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 47/221 (21%)

Query: 312 PCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSD------ESPLTPLEVTKLPV 365
           P PP      +PPP P  L    P   +  +    +P+S       E  L  L+  +   
Sbjct: 15  PPPP------VPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68

Query: 366 LENVSYMKQPAGASPSTLPSH--VPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRT 423
            + +  + QP    P  LP    +PG            G     P     PP P+  Y+ 
Sbjct: 69  QKQMQCVLQPHHLPPPPLPPPPVMPG---------GGYGDWQPPPPPMPPPPGPALSYQK 119

Query: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSL------------------ 465
           Q  + +   H     P      L P+ L+ PP    V  GS                   
Sbjct: 120 QQQYKHQMLHHQRDGPPG----LVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYY 175

Query: 466 --SRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRS 504
             + S P +P + P P     ++   A   +Y ++   S+S
Sbjct: 176 PPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQS 216


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 85/321 (26%), Positives = 117/321 (36%), Gaps = 47/321 (14%)

Query: 291  SCSSQCATPTVP---DLDFAKASVPCPPKG---LLCDIPPPFPNLLSHRPPLLVFPPAPV 344
            S S   ATP  P         A  P PP     +L   P   P L S + P+ V  P+  
Sbjct: 1578 SASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSST 1637

Query: 345  HCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPA 404
              +  +  SP+        PVL   S         PS LPS           Q  AL PA
Sbjct: 1638 PGTSLASASPVP----APTPVLAPSSTQTMLPAPVPSPLPSPA-------STQTLALAPA 1686

Query: 405  SATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTP-----LSLKRPPPYDA 459
             A P L  S P  +    T +P G   + + S +P S   SL P     LSL   PP   
Sbjct: 1687 LA-PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPAS---SLVPTPAQTLSLAPGPPLGP 1742

Query: 460  VHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFS 519
              + SL+ + P  P S   P       +  A+ +    AP   ++ T  SP    T   +
Sbjct: 1743 TQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLT-LSPAPVPTLGPA 1801

Query: 520  SGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQE 579
            + ++L    +S   ++ PA +++  L V +    PLP              SR PV   E
Sbjct: 1802 AAQTLALAPAS---TQSPASQAS-SLVVSASGAAPLPV----------TMVSRLPVSKDE 1847

Query: 580  WD------GTPGTPVVTSRLG 594
             D      G P  P   +  G
Sbjct: 1848 PDTLTLRSGPPSPPSTATSFG 1868



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 88/369 (23%), Positives = 142/369 (38%), Gaps = 56/369 (15%)

Query: 302  PDLDFAKASVPCPP--KGLLCDIPPPFPNLLSHRP---PLLVFPPAPVHCS---PNSDES 353
            P L  A+A +P P   + LL  +  P P + +  P   PL +  P  V  S   P S   
Sbjct: 1356 PTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPM 1415

Query: 354  PLTPLEVTKLPVLENVSYMKQPAGAS-----PSTLPSHVPGHAKLEKEQAAALGPASATP 408
            P+        PV   VS    P  +S     P+TLP+  P  A L    +A L  +++ P
Sbjct: 1416 PIPNSSPLASPVSSTVSV---PLSSSLPISVPTTLPA--PASAPLTIPISAPLTVSASGP 1470

Query: 409  ALSSSPPPPSTLYRTQSPHG---YPKSHSTSPSPVSMGRSLTP-LSLKRPPPYDAVHSGS 464
            AL +S  PP       +P      P   S S S +++G +  P LS  + P +  +    
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLL---- 1526

Query: 465  LSRSSPSVP--HSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPT-SPLEELTSLFSSG 521
            L+ +S  VP  +ST  P         +A  + + +AP  + ++    +P    +   ++ 
Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATP 1586

Query: 522  RSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWD 581
             + +    +   +  PA               PLP L          +SS+ PV      
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLA-----------PLPVLAPSPGAAPVLASSQTPVPVMAPS 1635

Query: 582  GTPGTPVVTSRLGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQ 641
             TPGT +        S SP          P  +  L  S++ + +P P  +PL   +  Q
Sbjct: 1636 STPGTSL-------ASASPV---------PAPTPVLAPSSTQTMLPAPVPSPLPSPASTQ 1679

Query: 642  QSQVPSSLA 650
               +  +LA
Sbjct: 1680 TLALAPALA 1688



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 76/319 (23%), Positives = 113/319 (35%), Gaps = 51/319 (15%)

Query: 320  CDIPPPFPNLLSHRPP----LLVFPPAPVHCSPNSDESPLTPLE--VTKLPV-LENVSYM 372
            C  PP      +H PP     LV P +P+   P     P  P+   VT LP+ L   + +
Sbjct: 2499 CTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGP-----PSVPISASVTNLPLGLRPEAEL 2553

Query: 373  KQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPA-----------LSSSPPPPS-TL 420
               A ASP +L   +   A  E    + + P    P            LS +P  PS TL
Sbjct: 2554 CAQALASPESL--ELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTL 2611

Query: 421  YRTQSPHGYPKSHSTSPSPVSM-----------------GRSLTPLSLKRPPPYDAVHSG 463
                 P+G  +    S    ++                 G  L P +    P  + + + 
Sbjct: 2612 EAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEAD 2671

Query: 464  SLSR--SSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSG 521
              S   +    P S+P    Q+      AA +T  +A       +P  P    TS     
Sbjct: 2672 RTSEELTEAKTPTSSPEK-PQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVE- 2729

Query: 522  RSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWD 581
               +R   +GR  + P  K   +L  R  +     +L  + R   GA+S+  P    E  
Sbjct: 2730 ---IRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVP-GVSETS 2785

Query: 582  GTPGTPVVTSRLGRCSVSP 600
             +PG+P V S  G  S  P
Sbjct: 2786 ASPGSPSVRSMSGPESSPP 2804



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 76/304 (25%), Positives = 103/304 (33%), Gaps = 54/304 (17%)

Query: 297  ATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCS-PNSDESPL 355
            +T T P    A+  VP P        P P P   S    +    P PV    P S  +P+
Sbjct: 2422 STTTPPRCSPARERVPRPA-------PRPRPTPASAPAAIPALVPVPVSAPVPISAPNPI 2474

Query: 356  TPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPP 415
            T L V  LP     S +  P  +SP+  P                  P + TP  + +PP
Sbjct: 2475 TILPVHILPSPPPPSQI--PPCSSPACTP------------------PPACTPPPAHTPP 2514

Query: 416  PPSTLYRTQS------PHGYPKSHSTSPSPVSM--GRSLTPLSLKRPPPYDAVHSGSLSR 467
            P  T   T S      P   P S S +  P+ +     L   +L  P   +     S   
Sbjct: 2515 PAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSET 2574

Query: 468  SSPS-VPHS-------TPRPVSQDGAKMVNAAVN---TYGAAPGGSRSRTPTSPLEELTS 516
            SS S VP            PVS+    +  +A +     G+ P G     P S      +
Sbjct: 2575 SSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLT 2634

Query: 517  LFSSGRSL-LRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPV 575
            +   G  L L  S S      P+  S E L+      EPL      E      + +  P 
Sbjct: 2635 VLPEGEELPLCVSESNGLELPPSAASDEPLQ------EPLEADRTSEELTEAKTPTSSPE 2688

Query: 576  KAQE 579
            K QE
Sbjct: 2689 KPQE 2692



 Score = 33.1 bits (74), Expect = 0.83
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 10/217 (4%)

Query: 297  ATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPL- 355
            A P  P L  + AS       L     P   +  +   PLL+ P +      NS  +P  
Sbjct: 1486 AAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPAC 1545

Query: 356  TPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPP 415
            +P+ V    +         PA A  S L         L    A    P +A  A S +PP
Sbjct: 1546 SPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPP 1605

Query: 416  PPSTLYRTQSPHGYP-KSHSTSPSPVSMGRSLTPLSLKR----PPPYDAVHSGSLSRSSP 470
                     SP   P  + S +P PV    S    SL      P P   +   S     P
Sbjct: 1606 LAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLP 1665

Query: 471  S-VPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRT 506
            + VP   P P S     +  A   T G   G S S+T
Sbjct: 1666 APVPSPLPSPASTQTLALAPALAPTLG---GSSPSQT 1699



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 17/187 (9%)

Query: 341  PAPVHCSPNSDESPLTPLEVTKLPVLENVSY------MKQPAGASPSTLPSHVPGHAKLE 394
            P PV    N    P+   E   + V+ N         ++ P G   S  P+  P    L 
Sbjct: 987  PKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLP 1046

Query: 395  KEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTP---LSL 451
                 +  PA      +S PP P  L   Q   G       SP  V  G S  P   LSL
Sbjct: 1047 ASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSL 1106

Query: 452  KRPPP-----YDAVHSGSLSRSSP-SVP--HSTPRPVSQDGAKMVNAAVNTYGAAPGGSR 503
            K  PP       A   GS S   P +VP  ++ P   +   +     A  T   AP  + 
Sbjct: 1107 KPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAP 1166

Query: 504  SRTPTSP 510
             R   SP
Sbjct: 1167 QRLILSP 1173



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 42/160 (26%), Positives = 54/160 (33%), Gaps = 19/160 (11%)

Query: 101  APQDRLPHPCSSGFSVRSQ-SLHSVGGTDDDSSCGS-----------RRQPPPKPKRDPS 148
            AP   LP P    F  R    L   GG   ++  G+           RR  PPK  R P+
Sbjct: 2812 APSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPA 2871

Query: 149  TKLSTSSETVSSTAASK-SGKTP---ERTEASAKPRPHSDEYSKKIP-PPKPKRNPNTQL 203
                   E  SST   K +G  P     T   A P           P  P+P   PN  L
Sbjct: 2872 DAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLL 2931

Query: 204  STSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEP 243
            S    E   +   P+   LP   ++S  G    +   + P
Sbjct: 2932 SPV--EKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPP 2969



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 8/63 (12%)

Query: 323  PPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV-TKLPVLENVSYMKQPAGASPS 381
            PPP P+ L+  PPLLV P A V        + +T + + T  P  +     K P    PS
Sbjct: 2968 PPPHPSPLTPLPPLLVCPTATV-------ANTVTTVTISTSPPKRKRGRPPKNPPSPRPS 3020

Query: 382  TLP 384
             LP
Sbjct: 3021 QLP 3023


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 129/564 (22%), Positives = 186/564 (32%), Gaps = 81/564 (14%)

Query: 47  DRLRNETNLAYLKEKNEKRRRQEEAIKRIGGEVG--RGHEGSYVGKHFRMGFMTMPAPQD 104
           D    ET L+ LKEK +KR  +EE    + G+    R H+ S  G       +    P  
Sbjct: 40  DPCAKETVLSALKEKEKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPAS 99

Query: 105 RLPHPCSSGFSVRSQS----LHSVGGTDDDSS-CGSRRQPPPKPKRDPSTKLSTSSETVS 159
            +P P S    + SQS    L+    +   SS  G+     P   R+  T   +S+  +S
Sbjct: 100 FVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGIS 159

Query: 160 -------------STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
                        S+ AS   +TPER     +        S   P    +    +Q   +
Sbjct: 160 QLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADR---ESQGEKA 216

Query: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEA 266
            D T  KK      S P  S   +           E + +     +      ED D  + 
Sbjct: 217 ADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKK 276

Query: 267 VYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFA----KASVPCPPKGLLCDI 322
              +      +D    A         +S   TP +    F      A+   PP  LL   
Sbjct: 277 ASLQWFNQALEDKSDAAS--------NSVTETPPITQPSFTFTLPAAAPASPPTSLLAPS 328

Query: 323 PPPFPNLLS--HRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASP 380
             P    L     PP L  PP P      + E+   P   + LP          P G S 
Sbjct: 329 TNPLLESLKKMQTPPSL--PPCPESAGAATTEALSPPKTPSLLP----------PLGLSQ 376

Query: 381 STLPSHVPGHAKLEKEQAAALG--PA-SATPALSSSPPP------PSTLYRTQSPHGYPK 431
           S  P  +P  +   K     LG  PA S  PA  +  PP       +    T +P   PK
Sbjct: 377 SGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPK 436

Query: 432 ------SHSTSP-SPVSMGRSLTPLSLK-------------RPPPYDAVHSGSLSRSSPS 471
                 + +TSP SP +   S  P   K               PP  +V + + S SS  
Sbjct: 437 QSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLP 496

Query: 472 VPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLF---SSGRSLLRKS 528
              ST  P  Q     +    +    AP   ++ TP +       LF   +S  S +   
Sbjct: 497 TTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPI 556

Query: 529 SSGRRSKEPAEKSTEELKVRSHST 552
           +S   S + A K      + S S+
Sbjct: 557 TSASPSTDSASKPAFGFGINSVSS 580


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 55/199 (27%), Positives = 70/199 (35%), Gaps = 39/199 (19%)

Query: 310 SVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPA-------PVHCSPNSDESPLTPLEVTK 362
           S P PP      IPPP P+    +PP    PP        P H  P+  + P  P + + 
Sbjct: 54  SGPKPP------IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSS 107

Query: 363 LPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYR 422
            PV+          G++P    S  P           +  P  + P  + +PPP  T   
Sbjct: 108 KPVVAQGPGPAPGVGSAPPASSSAPPA------TPPTSGAPPGSGPGPTPTPPPAVT--- 158

Query: 423 TQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQ 482
             +P G P      P+P S G   TP     PPP  A   G      P  P   P P   
Sbjct: 159 -SAPPGAPP-----PTPPSSGVPTTPPQAGGPPPPPAAVPG----PGPG-PKQGPGPGGP 207

Query: 483 DGAKMVNAAVNTYGAAPGG 501
            G KM        G  PGG
Sbjct: 208 KGGKMPG------GPKPGG 220



 Score = 37.0 bits (84), Expect = 0.057
 Identities = 33/127 (25%), Positives = 40/127 (31%), Gaps = 12/127 (9%)

Query: 388 PGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRT----QSPHGYPKSHSTSPSPVSMG 443
           PG    +       GP  + P     PPPP    +     Q P   P  H   P P    
Sbjct: 36  PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQ 95

Query: 444 RSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSR 503
           +   P     PPP D+          P+    +  P S        A   T GA PG   
Sbjct: 96  QQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP---ATPPTSGAPPGSGP 147

Query: 504 SRTPTSP 510
             TPT P
Sbjct: 148 GPTPTPP 154


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 105/535 (19%), Positives = 168/535 (31%), Gaps = 80/535 (14%)

Query: 122 HSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRP 181
           HSV    + SS  S        ++  S+K S ++  +      K  K   RT+    P+P
Sbjct: 117 HSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKK-NRTKKKPTPKP 175

Query: 182 HS--------DEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGS 233
                     D    K+  P      + ++STS   T  K   PR  SLP +S  S+  S
Sbjct: 176 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR-PSLPPNSDTSKETS 234

Query: 234 PAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCS 293
              + E      +E       + +   D + +                 AK        S
Sbjct: 235 LTVNKETT----VETKETTTTNKQTSTDGKEKTT--------------SAKETQSIEKTS 276

Query: 294 SQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDES 353
           ++   PT   L           KG                 P L  P  P   +P    S
Sbjct: 277 AKDLAPTSKVLAKPTPKAETTTKG-----------------PALTTPKEPTPTTPKEPAS 319

Query: 354 PLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS 413
             TP E T   +    +  K+PA  +  + P+     A    ++ A   P    P  +  
Sbjct: 320 T-TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378

Query: 414 PPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVP 473
           P P +T     +P     +    P+P +  +   P + K P P           ++P  P
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTT-PKEPAPTTPKEPTP-----------TTPKEP 426

Query: 474 HSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRR 533
             T +  +    K           AP   +   PT+P E   +          K  S   
Sbjct: 427 APTTKEPAPTTPK---------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477

Query: 534 SKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRL 593
            KEPA  +T+     + + EP P            ++ +EP      +  P TP   +  
Sbjct: 478 PKEPAPTTTK--SAPTTTKEPAPTTTKS-----APTTPKEPSPTTTKEPAPTTPKEPAPT 530

Query: 594 GRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVPSS 648
                +PT       + PK        A T+   P   TP   +    +   P++
Sbjct: 531 TPKKPAPTTPKEPAPTTPK------EPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 99/505 (19%), Positives = 162/505 (32%), Gaps = 52/505 (10%)

Query: 137 RQPPPKPKRDPSTKLSTSSETV----SSTAASKSGKTPERTEASAKPRPHSDEYSKKIPP 192
           ++P P   ++P+      + T     + TA  K   T  +  A   P+  +   +K+  P
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP 475

Query: 193 PKPKRNPNTQLSTSFDETYIKKHGPRRT----SLPRDSSLSQMGSPAGD-PEEEEPVYIE 247
             PK    T  +T    T  K+  P  T    + P++ S +    PA   P+E  P   +
Sbjct: 476 TTPKEPAPT--TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533

Query: 248 MVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDL--- 304
                          +  A     K               +    + +  TPT P+    
Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAP 593

Query: 305 DFAKASVPCPPKGLLCDIP----PPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
              +   P  P+ L    P    P  P   +   P    P  P   +P + + P      
Sbjct: 594 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 653

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420
              P     +    P G +P+TL    P   K    +  A        + +   P P+T 
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT- 712

Query: 421 YRTQSPHGYPKSHSTSPSPV-------SMGRSLTPLSLKRPPPYDAVHSGSLSRSSPS-- 471
                P G   +    P+P        +  +   P +LK P P       +  + +P   
Sbjct: 713 -----PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP------TTPKKPAPKEL 761

Query: 472 VPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSG 531
            P +T  P S    K   A       AP   +   PT+P +   +   +      + S+ 
Sbjct: 762 APTTTKGPTSTTSDK--PAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTP 819

Query: 532 RRSKEPA------EKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPG 585
             +KEP       ++ST EL     S EP PK         G  +++ P   +    T  
Sbjct: 820 TTTKEPTTIHKSPDESTPEL-----SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 874

Query: 586 TPVVTSRLGRCSVSPTLLAGNHSSE 610
               T R  R +   T  A   + E
Sbjct: 875 KDKTTERDLRTTPETTTAAPKMTKE 899



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 114/537 (21%), Positives = 178/537 (33%), Gaps = 89/537 (16%)

Query: 120 SLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKP 179
           SL     T  ++S    ++   + K   +T   TS++    T ++K  ++ E+T  SAK 
Sbjct: 222 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT--SAKD 279

Query: 180 RPHSDEYSKKIPPPKPKRNPNTQ---LSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAG 236
              +   SK +  P PK    T+   L+T  + T      P  T+ P++ + + + S   
Sbjct: 280 LAPT---SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT-PKEPTPTTIKSAPT 335

Query: 237 DPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQC 296
            P+E  P                    +++     K P      + A             
Sbjct: 336 TPKEPAPT------------------TTKSAPTTPKEPAPTTTKEPAP------------ 365

Query: 297 ATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLT 356
            TP  P     K   P   K        P P       P     PAP      +  +P  
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE 425

Query: 357 PLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPP 416
           P   TK P     +  K+PA  +P       P      KE      PA  TP      P 
Sbjct: 426 PAPTTKEPA---PTTPKEPAPTAPKKPAPTTP------KE------PAPTTP----KEPA 466

Query: 417 PSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHST 476
           P+T   T+ P     S +T   P        P + K P P       + ++S+P+ P   
Sbjct: 467 PTT---TKEP-----SPTTPKEPAPTTTKSAPTTTKEPAP-------TTTKSAPTTP-KE 510

Query: 477 PRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKE 536
           P P +        A       AP   +   PT+P E   +          K  +    KE
Sbjct: 511 PSPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 566

Query: 537 PAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSRE---PVKAQEW-DGTPGTPVVTSR 592
           PA  + +E      +    PK          A ++ E   P   +E    TP  P  T+ 
Sbjct: 567 PAPTTPKE------TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620

Query: 593 LGRCSVSPTLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSDLQQSQVPSSL 649
                 +P   A N   EP  +     + +T   P P+ TP   +    +   P++L
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT-TPKETAPTTPKGTAPTTL 676



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 7/76 (9%)

Query: 150  KLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPP-KPKRNPNTQLSTSFD 208
            K++T+ +T+++T      +   + E +AKP+  +       P P KP + P    ST   
Sbjct: 943  KVTTTKKTITTT------EIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 996

Query: 209  ETYIKKHGPRRTSLPR 224
            +T  +   P+ T  PR
Sbjct: 997  KTMPRVRKPKTTPTPR 1012



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 21/65 (32%), Positives = 31/65 (47%)

Query: 507 PTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHH 566
           PTSP     +   SG S   KS++ R  K P +K T+++      TE     +N+E    
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128

Query: 567 GASSS 571
            +SSS
Sbjct: 129 SSSSS 133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.127    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,665,494
Number of Sequences: 37866
Number of extensions: 2107898
Number of successful extensions: 15126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 1125
Number of HSP's that attempted gapping in prelim test: 10749
Number of HSP's gapped (non-prelim): 4812
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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