Guide to the Human Genome
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Name: APC Sequence: fasta or formatted (2843aa) NCBI GI: 189011566
Description:

adenomatous polyposis coli

Referenced in:

Cytoskeleton
Additional Interaction Domain Families
Wnt Signals

Other entries for this name:
alt mRNA [2843aa] adenomatous polyposis coli
alt mRNA [2843aa] adenomatous polyposis coli
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2        177           5
 C cysteine            1.3         38           1
 D aspartate           5.2        148           4
 E glutamate           7.4        209           4
 F phenylalanine       1.7         47           1
 G glycine             5.2        147           3
 H histidine           2.4         67           2
 I isoleucine          4.0        115           2
 K lysine              7.0        199           4
 L leucine             7.2        205           3
 M methionine          2.0         57           1
 N asparagine          5.6        158           3
 P proline             6.3        179           5
 Q glutamine           5.4        154           2
 R arginine            5.7        163           2
 S serine             15.3        436           6
 T threonine           5.9        167           2
 V valine              4.0        113           1
 W tryptophan          0.5         14           1
 Y tyrosine            1.8         50           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   adenomatous polyposis coli 
APC                   1.000   adenomatous polyposis coli 
APC                   1.000   adenomatous polyposis coli 
APC2                  0.152   adenomatosis polyposis coli 2 
DSPP                  0.013   dentin sialophosphoprotein preproprotein 
SRRM2                 0.012   splicing coactivator subunit SRm300 
MUC17                 0.012   mucin 17 
SRRM1                 0.009   serine/arginine repetitive matrix 1 
LOC100170229          0.008   hypothetical protein LOC100170229 
MUC21                 0.008   mucin 21 
TCOF1                 0.008   Treacher Collins-Franceschetti syndrome 1 isoform e...
MED1                  0.008   mediator complex subunit 1 
AFF1                  0.008   myeloid/lymphoid or mixed-lineage leukemia trithorax ...
TCOF1                 0.008   Treacher Collins-Franceschetti syndrome 1 isoform a ...
MUC12                 0.007   PREDICTED: mucin 12 
MUC12                 0.007   PREDICTED: mucin 12, cell surface associated 
MUC6                  0.007   mucin 6, gastric 
KIAA1853              0.007   KIAA1853 protein 
BAT2D1                0.007   HBxAg transactivated protein 2 
MUC12                 0.007   PREDICTED: mucin 12 
DPCR1                 0.007   diffuse panbronchiolitis critical region 1 protein ...
MUC12                 0.006   PREDICTED: mucin 12 
ASXL3                 0.006   additional sex combs like 3 
TCOF1                 0.006   Treacher Collins-Franceschetti syndrome 1 isoform f...
GPRIN1                0.006   G protein-regulated inducer of neurite outgrowth 1 ...
NEFH                  0.006   neurofilament, heavy polypeptide 200kDa 
TCOF1                 0.006   Treacher Collins-Franceschetti syndrome 1 isoform d...
NAV3                  0.006   neuron navigator 3 
MUC16                 0.005   mucin 16 
AFF4                  0.005   ALL1 fused gene from 5q31 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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