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Search of human proteins with 153791300
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153791300 SDA1 domain containing 1 [Homo sapiens]
(687 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153791300 SDA1 domain containing 1 [Homo sapiens] 1357 0.0
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 55 2e-07
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 52 1e-06
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 50 9e-06
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 49 2e-05
gi|148746195 trichohyalin [Homo sapiens] 45 2e-04
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)... 44 5e-04
gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa... 43 8e-04
gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s... 43 8e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 43 0.001
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|50962882 G patch domain containing 8 [Homo sapiens] 42 0.002
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 42 0.002
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 41 0.004
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 41 0.004
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 40 0.006
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 40 0.006
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 40 0.006
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 40 0.007
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 40 0.007
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 40 0.007
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 40 0.007
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.009
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 39 0.012
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 39 0.012
gi|146260271 hypothetical protein LOC129881 [Homo sapiens] 39 0.012
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens] 39 0.016
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 39 0.021
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 39 0.021
gi|34878777 ring finger protein 20 [Homo sapiens] 39 0.021
>gi|153791300 SDA1 domain containing 1 [Homo sapiens]
Length = 687
Score = 1357 bits (3512), Expect = 0.0
Identities = 687/687 (100%), Positives = 687/687 (100%)
Query: 1 MSNRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELV 60
MSNRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELV
Sbjct: 1 MSNRNNNKLPSNLPQLQNLIKRDPPAYIEEFLQQYNHYKSNVEIFKLQPNKPSKELAELV 60
Query: 61 MFMAQISHCYPEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLE 120
MFMAQISHCYPEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLE
Sbjct: 61 MFMAQISHCYPEYLSNFPQEVKDLLSCNHTVLDPDLRMTFCKALILLRNKNLINPSSLLE 120
Query: 121 LFFELFRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMS 180
LFFELFRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMS
Sbjct: 121 LFFELFRCHDKLLRKTLYTHIVTDIKNINAKHKNNKVNVVLQNFMYTMLRDSNATAAKMS 180
Query: 181 LDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDG 240
LDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDG
Sbjct: 181 LDVMIELYRRNIWNDAKTVNVITTACFSKVTKILVAALTFFLGKDEDEKQDSDSESEDDG 240
Query: 241 PTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKL 300
PTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKL
Sbjct: 241 PTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKL 300
Query: 301 LKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQA 360
LKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQA
Sbjct: 301 LKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQREVTKILLFAAQA 360
Query: 361 SHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQY 420
SHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQY
Sbjct: 361 SHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKEITARCPLAMTEELLQDLAQY 420
Query: 421 KTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGAE 480
KTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGAE
Sbjct: 421 KTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGAE 480
Query: 481 VLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKA 540
VLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKA
Sbjct: 481 VLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKA 540
Query: 541 KAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIE 600
KAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIE
Sbjct: 541 KAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIE 600
Query: 601 RLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNV 660
RLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNV
Sbjct: 601 RLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNV 660
Query: 661 RSKNKRSFREKQLALRDALLKKRKRMK 687
RSKNKRSFREKQLALRDALLKKRKRMK
Sbjct: 661 RSKNKRSFREKQLALRDALLKKRKRMK 687
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 55.5 bits (132), Expect = 2e-07
Identities = 57/246 (23%), Positives = 111/246 (45%), Gaps = 39/246 (15%)
Query: 458 ASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQH 517
+ IE V+EY E + ++ VE+EE+ DED E + E+ +A+ E + +
Sbjct: 2 SDIEEVVEEYEEEEQEE-------AAVEEEEDWREDEDEQEEAA-EEDAEAEAETEETRA 53
Query: 518 SSDEEQQEISKKLNSMPMEERKAKAAAISTSRVL------TQEDFQKIRMAQMRKELDAA 571
DEE++E +K+ PMEE K K + + V + DF I +M K+L+
Sbjct: 54 EEDEEEEE-AKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLN-- 110
Query: 572 PGKSQKRKYIEIDSDEEPRGELLSLRD-----------IERLHKKPKSDKETRLATAMAG 620
+ Q ++ ++ EL+SL+D +R+ + + +++ RLA
Sbjct: 111 --ELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLA----- 163
Query: 621 KTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALL 680
+E R++ + N + KKK + MM +++ K R+ + + +L
Sbjct: 164 ----EERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTERKSGKRQTEREKKKKIL 219
Query: 681 KKRKRM 686
+R+++
Sbjct: 220 AERRKV 225
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/226 (23%), Positives = 102/226 (45%), Gaps = 38/226 (16%)
Query: 480 EVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERK 539
EV+E +EE E E+ E E+ +A+ E + + DEE++E +K+ PMEE K
Sbjct: 6 EVVEEYEEEEQEEQEEAAE-----EDAEAEAETEETRAEEDEEEEE-AKEAEDGPMEESK 59
Query: 540 AKAAAISTSRVL------TQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGEL 593
K + + V + DF I +M K+L+ + Q ++ ++ EL
Sbjct: 60 PKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLN----ELQALIEAHFENRKKEEEEL 115
Query: 594 LSLRD-----------IERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTN 642
+SL+D +R+ + + +++ RLA +E R++ + N +
Sbjct: 116 VSLKDRIERRRAERAEQQRIRNEREKERQNRLA---------EERARREEEENRRKAEDE 166
Query: 643 KEKKKQKNFMMM--RYSQNVRSKNKRSFREKQLALRDALLKKRKRM 686
KKK + MM Y Q +++ K R+ + + +L +R+++
Sbjct: 167 ARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKV 212
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 49.7 bits (117), Expect = 9e-06
Identities = 49/221 (22%), Positives = 98/221 (44%), Gaps = 31/221 (14%)
Query: 484 VEKEENAENDEDGWESTSLSEEEDADGEW-IDVQHSSDEEQQEISKKLNSMPMEERKAKA 542
VE+ E E +E E + EEDA+ E + + ++E++E +K+ PMEE K K
Sbjct: 8 VEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 67
Query: 543 AAISTSRVL------TQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSL 596
+ + V + DF I +M K+L+ + Q ++ ++ EL+SL
Sbjct: 68 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLN----ELQALIEAHFENRKKEEEELVSL 123
Query: 597 RD-----------IERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEK 645
+D +R+ + + +++ RLA +E R++ + N + K
Sbjct: 124 KDRIERRRAERAEQQRIRNEREKERQNRLA---------EERARREEEENRRKAEDEARK 174
Query: 646 KKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRM 686
KK + MM +++ K R+ + + +L +R+++
Sbjct: 175 KKALSNMMHFGGYIQKTERKSGKRQTEREKKKKILAERRKV 215
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/226 (24%), Positives = 100/226 (44%), Gaps = 41/226 (18%)
Query: 484 VEKEENAENDEDGWESTSLSEEEDADGEW-IDVQHSSDEEQQEISKKLNSMPMEERKAKA 542
VE+ E E +E E + EEDA+ E + + ++E++E +K+ PMEE K K
Sbjct: 8 VEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 67
Query: 543 AAISTSRVL------TQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSL 596
+ + V + DF I +M K+L+ + Q ++ ++ EL+SL
Sbjct: 68 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLN----ELQALIEAHFENRKKEEEELVSL 123
Query: 597 RD-----------IERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEK 645
+D +R+ + + +++ RLA +E R++ + N + K
Sbjct: 124 KDRIERRRAERAEQQRIRNEREKERQNRLA---------EERARREEEENRRKAEDEARK 174
Query: 646 KKQKNFMM------MRYSQNVRSKNKR-SFREKQLALRDALLKKRK 684
KK + MM + +Q R KR + REK+ + L ++RK
Sbjct: 175 KKALSNMMHFGGYIQKQAQTERKSGKRQTEREKK---KKILAERRK 217
Score = 36.2 bits (82), Expect = 0.10
Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 29/215 (13%)
Query: 457 EASIEARVQEYGELDAKDYIPGAEVLEV-----EKEENAENDEDGWESTS---------- 501
E EA V+E E +D AE E E+EE A+ EDG S
Sbjct: 14 EEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN 73
Query: 502 LSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRM 561
L + DGE +D D ++ + K LN E +A A +R +E+ +
Sbjct: 74 LVPPKIPDGERVDF---DDIHRKRMEKDLN-----ELQALIEAHFENRKKEEEE-----L 120
Query: 562 AQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLR-DIERLHKKPKSDKETRLATAMAG 620
++ ++ + +++ I + ++E + L R E + K++ E R A++
Sbjct: 121 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN 180
Query: 621 KTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMR 655
+++K+ +T S E++K+K + R
Sbjct: 181 MMHFGGYIQKQAQTERKSGKRQTEREKKKKILAER 215
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 45.4 bits (106), Expect = 2e-04
Identities = 42/218 (19%), Positives = 94/218 (43%), Gaps = 29/218 (13%)
Query: 484 VEKEENAENDEDGWESTSLS--EEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAK 541
+++EE E E L +EE+ W+ ++ EQQE ++ EER+ +
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 542 AAAISTSRVLTQEDFQKIRM-----AQMRKELDAAPGK----------SQKRKYIEIDSD 586
R+ QE+ ++++ Q+R+E + + Q+R+ + +
Sbjct: 518 -------RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 587 EEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKK 646
+E R + L R+ ER ++ K ++E RL + ++E V + + +E+
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRL-----KREEVERLEQEERREQRLKREEP 625
Query: 647 KQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRK 684
+++ + S+ + ++ R +Q R+ LK+ +
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663
Score = 39.3 bits (90), Expect = 0.012
Identities = 42/214 (19%), Positives = 98/214 (45%), Gaps = 12/214 (5%)
Query: 482 LEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEI-SKKLNSMPMEERKA 540
L++E+EE E E E E+E+ + + Q + QQ + S++ EER+
Sbjct: 489 LKLEEEERREQQERR-EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 541 KAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGE-LLSLRDI 599
+ + L QE ++ + + D + ++R+ + ++E R E L ++
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Query: 600 ERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMM----- 654
ERL ++ + +E RL + R++ ++ + + +E+++++ +
Sbjct: 608 ERLEQEER--REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 655 -RYSQNVRSKNKRSFREKQLALRDALLKKRKRMK 687
R Q ++ +++ RE++LA + + R+R+K
Sbjct: 666 ERLEQRLKREHEEERREQELA-EEEQEQARERIK 698
Score = 38.5 bits (88), Expect = 0.021
Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 28/214 (13%)
Query: 481 VLEVEKEENAENDEDGWESTS--LSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEER 538
+L ++E + E + W+ EEE + E D + QE + L EER
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR----EER 1325
Query: 539 KAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKR--KYIEIDSDEEPRG----- 591
+ K T R +E+ Q+ +E + P + Q+R K+ E + + +G
Sbjct: 1326 EEKRRRQETDRKFREEE-------QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 592 ELLSLRDIERLHKKPKSDKETRLATA---MAGKTDRK-----EFVRKKTKTNPFSSSTNK 643
E LR ER K K +++ R + DRK + + ++ + F +
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 644 EKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRD 677
+++++ + Q +R + R FRE++ L++
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Score = 37.4 bits (85), Expect = 0.047
Identities = 45/214 (21%), Positives = 96/214 (44%), Gaps = 34/214 (15%)
Query: 483 EVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERK--- 539
E+E++ E + E L EE++ + + Q+ +EE Q +K ++R
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK 1224
Query: 540 -----AKAAAISTSRVLTQ----EDFQKIRMAQMR-----KELDAAPGKSQKRKYIEIDS 585
K A+ ++V + E F+++ +Q+R ++L G+ Q+R D
Sbjct: 1225 WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER-----DR 1279
Query: 586 DEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDR-----KEFVRKKTKTNPFSSS 640
++E R R +R P+ ++ R A + DR K+ +R++ +
Sbjct: 1280 EQERR------RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 641 TNKEKKKQKNFMMMRYSQNVRSKNK-RSFREKQL 673
T+++ ++++ + R Q +R + + R FRE++L
Sbjct: 1334 TDRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
Score = 37.0 bits (84), Expect = 0.061
Identities = 42/206 (20%), Positives = 88/206 (42%), Gaps = 13/206 (6%)
Query: 483 EVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISK-KLNSMPMEERKAK 541
E E+E + + E L E++ +W+ + ++ +QE K +L EER+ +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 542 AAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGE-LLSLRDIE 600
+ + + Q+ R Q+R+E + + KR+ E + R E L E
Sbjct: 488 WLKLEEEE---RREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 601 RLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNV 660
R + K ++E RL + +R+E K+ + +E+++++ + + +
Sbjct: 545 RREQLLKREEEKRL------EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
Query: 661 RSKNKRSFREK--QLALRDALLKKRK 684
+ KR E+ Q R+ LK+ +
Sbjct: 599 EQRLKREEVERLEQEERREQRLKREE 624
Score = 34.3 bits (77), Expect = 0.39
Identities = 41/245 (16%), Positives = 105/245 (42%), Gaps = 7/245 (2%)
Query: 447 LQKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEE 506
L++K R + + E + + + E + K++ VL E+E+ E + EE+
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277
Query: 507 DADGEWIDVQHSSDEEQQEISKKLNSMPM----EERKAKAAAISTSRVLTQEDFQKIRMA 562
E +++ EE+Q+ + + EE + + + +E ++ R
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337
Query: 563 QMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKT 622
Q+R+E + + +R+ E +++ R E R ++L ++ + +E +L +
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ--QL 395
Query: 623 DRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKK 682
R++ +R++ + +E++ ++ + R + R + K ++ L+ ++
Sbjct: 396 RREQQLRREQQLRR-EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Query: 683 RKRMK 687
R +K
Sbjct: 455 RDWLK 459
Score = 34.3 bits (77), Expect = 0.39
Identities = 36/208 (17%), Positives = 93/208 (44%), Gaps = 15/208 (7%)
Query: 485 EKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAA 544
E++E E E+ E E+E+ + + + + +Q++ ++ E++ +
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 545 ISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLR-----DI 599
+ + L +E Q++R Q + + Q R+ ++ +++ R E R +
Sbjct: 383 LRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 600 ERLHKKPKSDKETRLA-TAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQ 658
ER ++ K ++E R +T+R E R+K + ++E+++++ ++ + +
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQL-----KRDQEEERRERWLKLEEEE 495
Query: 659 NVRSKNKR--SFREKQLALRDALLKKRK 684
+ +R R +Q R+ LK+++
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQE 523
Score = 33.5 bits (75), Expect = 0.67
Identities = 44/254 (17%), Positives = 107/254 (42%), Gaps = 33/254 (12%)
Query: 448 QKKFRGKPTEASIEARVQEYGELDAK-DYIPGAEVLEV-EKEENAENDEDGWESTS---L 502
Q++ R P E E R ++ E + + ++ E L+ E+ + + +EDG +
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 503 SEEEDADGEWI------------------DVQHSSDEEQQEISKKLNSMPMEERKAKAAA 544
S+E+ D +W +Q +EQQ + ++ + EER+ +
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 545 ISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHK 604
+ +E Q+ +R+E + + ++R+Y + ++ +LL E K
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG----EEPEK 980
Query: 605 KPKSDKETRLATAMAGKTDRKEFVR----KKTKTNPFSSSTNKEKKKQKNFMMMRYSQNV 660
+ + ++E + + + ++ +R K+ + K++ +Q+ ++R +
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040
Query: 661 R--SKNKRSFREKQ 672
R + +R +RE++
Sbjct: 1041 RRLQERERQYREEE 1054
Score = 32.3 bits (72), Expect = 1.5
Identities = 39/203 (19%), Positives = 89/203 (43%), Gaps = 18/203 (8%)
Query: 483 EVEKEENAENDEDGWESTSLSEE-EDADGEWIDVQHSSDEE-QQEISKKLNSMPMEERKA 540
E E++ E + E L EE E + ++ Q+ +EE QQE + L P + R+
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Query: 541 KAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIE 600
+ + +E+ Q+ +R+E + + +R+Y E + ++ +LL E
Sbjct: 1105 ERER----QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR----E 1156
Query: 601 RLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNV 660
K+ + + E + + + ++ +R++ + ++ ++++ + Q
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKR--RQERERQYREEEELQRQKRKQRY 1214
Query: 661 RSKNKRS------FREKQLALRD 677
R +++RS EK+ A+RD
Sbjct: 1215 RDEDQRSDLKWQWEPEKENAVRD 1237
Score = 30.8 bits (68), Expect = 4.4
Identities = 35/209 (16%), Positives = 85/209 (40%), Gaps = 15/209 (7%)
Query: 485 EKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAA 544
+++ E E + EEE+ + + +H + +QE+++ EE++
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE-------EEQEQARER 696
Query: 545 ISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHK 604
I + Q + A+ K + +R+ E + R L ++ ER H+
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756
Query: 605 KPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTN------KEKKKQKNFMMMRYSQ 658
+ + +++ R T ++ E R++ P +E+++++ + +
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 659 NVRSKNKRSFREKQLAL--RDALLKKRKR 685
+ + +R REK+L + L++R+R
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRER 845
Score = 30.0 bits (66), Expect = 7.4
Identities = 46/243 (18%), Positives = 105/243 (43%), Gaps = 28/243 (11%)
Query: 447 LQKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSE-E 505
LQ++ R K E + +E +L ++ E E EK E + + L + E
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLRE--EREKRRRQERERQYRKDKKLQQKE 970
Query: 506 EDADGEWIDVQHSSDEE-----QQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIR 560
E GE + + + E ++E+ ++ + EER+ + + +++ Q+
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
Query: 561 MAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLS-------LRDIERLHKKPK--SDKE 611
+R+E + + ++R+Y E + ++ +LL +++ER ++K + +E
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 612 TRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKN--KRSFR 669
+L K R+E R+ +E+ +Q+ ++R + R + +R +R
Sbjct: 1091 EQLLREEPEKRRRQERERQ---------CREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 670 EKQ 672
E++
Sbjct: 1142 EEE 1144
>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
[Homo sapiens]
Length = 731
Score = 43.9 bits (102), Expect = 5e-04
Identities = 46/190 (24%), Positives = 85/190 (44%), Gaps = 26/190 (13%)
Query: 485 EKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAA 544
E+EE + +D ES+S EEE+ + V + DE+ + K L+ + + K +A
Sbjct: 566 EEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDEKIAKYQKFLD----KAKAKKFSA 621
Query: 545 ISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHK 604
+ S+ L+++ F K ++RK +E D D+ + R +R +
Sbjct: 622 VRISKGLSEKIFAK---------------PEEQRKTLEEDVDDRAPSKKGKKRKAQREEE 666
Query: 605 KPKSDKETRLATAMAGKTDRKEFVRKK--TKTNPFSSSTNKEKKKQKNFMMMRYSQNVRS 662
+ S+K R T+ +R+ VR++ K T+ K + +N S+ +
Sbjct: 667 QEHSNKAPRALTS----KERRRAVRQQRPKKVGVRYYETHNVKNRNRNKKKTNDSEGQKH 722
Query: 663 KNKRSFREKQ 672
K K+ FR+KQ
Sbjct: 723 KRKK-FRQKQ 731
>gi|41406057 amyloid beta A4 protein isoform c precursor [Homo
sapiens]
Length = 695
Score = 43.1 bits (100), Expect = 8e-04
Identities = 51/221 (23%), Positives = 87/221 (39%), Gaps = 48/221 (21%)
Query: 474 DYIPGAE--VLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLN 531
DY G+E V+EV +EE E E + +E+D DG+ ++ EE +E
Sbjct: 216 DYADGSEDKVVEVAEEEEVAEVE---EEEADDDEDDEDGDEVE------EEAEE------ 260
Query: 532 SMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRG 591
P EE + +I+T+ T E +++ +R AA KY+E DE
Sbjct: 261 --PYEEATERTTSIATTTTTTTESVEEV----VRVPTTAASTPDAVDKYLETPGDENEHA 314
Query: 592 ELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNF 651
+K K E + M+ E ++ K P K K
Sbjct: 315 HF----------QKAKERLEAKHRERMSQVMREWEEAERQAKNLP---------KADKKA 355
Query: 652 MMMRYSQNVRSKNKRSFREKQ------LALRDALLKKRKRM 686
++ + + V S + + E+Q +A +A+L R+R+
Sbjct: 356 VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRL 396
>gi|209915570 amyloid beta A4 protein isoform e precursor [Homo
sapiens]
Length = 639
Score = 43.1 bits (100), Expect = 8e-04
Identities = 51/221 (23%), Positives = 87/221 (39%), Gaps = 48/221 (21%)
Query: 474 DYIPGAE--VLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLN 531
DY G+E V+EV +EE E E + +E+D DG+ ++ EE +E
Sbjct: 160 DYADGSEDKVVEVAEEEEVAEVE---EEEADDDEDDEDGDEVE------EEAEE------ 204
Query: 532 SMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRG 591
P EE + +I+T+ T E +++ +R AA KY+E DE
Sbjct: 205 --PYEEATERTTSIATTTTTTTESVEEV----VRVPTTAASTPDAVDKYLETPGDENEHA 258
Query: 592 ELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNF 651
+K K E + M+ E ++ K P K K
Sbjct: 259 HF----------QKAKERLEAKHRERMSQVMREWEEAERQAKNLP---------KADKKA 299
Query: 652 MMMRYSQNVRSKNKRSFREKQ------LALRDALLKKRKRM 686
++ + + V S + + E+Q +A +A+L R+R+
Sbjct: 300 VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRL 340
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/252 (21%), Positives = 110/252 (43%), Gaps = 30/252 (11%)
Query: 448 QKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGW--------ES 499
Q+++ + TE ++ Q+ DA++ + E E+EE + G E
Sbjct: 157 QERYEIEETE-TVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK 215
Query: 500 TSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKI 559
T+ S+EE + Q SS+E +QE EER+ + IS + +ED +
Sbjct: 216 TTESQEETVVMSLKNGQISSEEPKQE----------EEREQGSDEISHHEKMEEEDKE-- 263
Query: 560 RMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMA 619
R E + A ++++R+ I+ + D++ E + E+ + + +E M
Sbjct: 264 -----RAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 620 GKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRD-- 677
+ R R++ K ++ +++ K++ Q ++ + KR+ E+Q A +
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378
Query: 678 --ALLKKRKRMK 687
A ++++KR K
Sbjct: 379 EKAKVEEQKRNK 390
Score = 33.5 bits (75), Expect = 0.67
Identities = 51/284 (17%), Positives = 114/284 (40%), Gaps = 52/284 (18%)
Query: 449 KKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDA 508
K+ + E + +E + + I E E+ + A +E E + EE+
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE---EEKAKVEEQKR 388
Query: 509 DGEWIDVQHSSDEEQ---QEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMR 565
+ + + +H+ E + +++ +K+ + E+KA+ + T+ + Q + + ++ R
Sbjct: 389 NKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKR 448
Query: 566 KEL--DAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSD-------------- 609
++L D K ++ K +I D+EP+ E+ S D ++ + KS
Sbjct: 449 EKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTEN 508
Query: 610 -------------KETRLATAMA------------GKTDRKEFVRKKTKTNPFSSSTNKE 644
KE A + G+T+ +EF + K K + +
Sbjct: 509 TFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEEL 568
Query: 645 KKKQKNFMMMRYSQNVRSKNKRSFR-----EKQLALRDALLKKR 683
KKK++ + + R K + + R E++ L++ + ++R
Sbjct: 569 KKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 612
Score = 30.0 bits (66), Expect = 7.4
Identities = 48/233 (20%), Positives = 96/233 (41%), Gaps = 18/233 (7%)
Query: 463 RVQEYGELDAKDYIPGAEVLEVEKEENAENDED--GWESTSLSEEEDADGEWIDVQHSSD 520
R +E + + I E E+ + + +E E + EEE E + +
Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE 377
Query: 521 EEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKI-------RMAQMRKELDAAPG 573
EE+ ++ ++ + +EE+K A+ +++ ++ QKI + AQ K A
Sbjct: 378 EEKAKVEEQKRNKQLEEKK---HAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLK 434
Query: 574 KSQKRKYIEIDSDEEP-RGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKE-FVRKK 631
K + K ++ + E + + + + E +K K DKE + + DRK+ F K
Sbjct: 435 KQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPK--EEVKSFMDRKKGFTEVK 492
Query: 632 TKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRK 684
++ F T+K K + F +V +K + + R L++R+
Sbjct: 493 SQNGEF--MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRR 543
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 3/157 (1%)
Query: 516 QHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKS 575
+ + ++E K+ +ER+ K R +E ++ R + +K G+
Sbjct: 53 ERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRR 112
Query: 576 QKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTN 635
+++K E +E E R+ +R ++ K ++ R GK +RK RKK +
Sbjct: 113 ERKKKKE---RKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE 169
Query: 636 PFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQ 672
KE+KK++ R + R K +R +E++
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Score = 38.5 bits (88), Expect = 0.021
Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 19/160 (11%)
Query: 526 ISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDS 585
ISK E +K + R +E ++ + +K GK ++RK E +
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 586 DEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEK 645
+ R E R KK K +E + + R+E RKK K NK++
Sbjct: 85 QRKERRE-----KERRKRKKEKKKRERK-------QRGRRE--RKKKKERKERERENKQR 130
Query: 646 KKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKR 685
+++K R + + + K REK+ R+ KKRK+
Sbjct: 131 RERK-----RKKRRKKKRRKERKREKERGKRERKRKKRKK 165
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/136 (23%), Positives = 67/136 (49%), Gaps = 22/136 (16%)
Query: 561 MAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKS--DKETRLATAM 618
M +M ELD A +++R+ +E++ + D E L +K K DKE +A A+
Sbjct: 81 MGRMEMELDYAEDATERRRVLEVEKE-----------DTEELRQKYKDYVDKEKAIAKAL 129
Query: 619 AGKTDR-------KEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREK 671
K++ + + N +S + K++ K+ +++NV S++++ +++
Sbjct: 130 EDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFARNVSSRSRKDEKKQ 189
Query: 672 QLALR--DALLKKRKR 685
+ ALR L ++RK+
Sbjct: 190 EKALRRLHELAEQRKQ 205
Score = 31.2 bits (69), Expect = 3.3
Identities = 40/170 (23%), Positives = 70/170 (41%), Gaps = 26/170 (15%)
Query: 445 QMLQKKFRGKPTEASIEARVQEYG------ELD-AKDYIPGAEVLEVEKEENAENDE--- 494
Q L K +G+ I + G ELD A+D VLEVEKE+ E +
Sbjct: 57 QGLGKSLQGRTDPIPIVVKYDVMGMGRMEMELDYAEDATERRRVLEVEKEDTEELRQKYK 116
Query: 495 ---DGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMP---------MEERKAKA 542
D ++ + + E+ + ++ ++ QE +NS +++R+
Sbjct: 117 DYVDKEKAIAKALEDLRANFYCELCDKQYQKHQEFDNHINSYDHAHKQRLKDLKQREFAR 176
Query: 543 AAISTSRVLTQEDFQKIR----MAQMRKELDAAPGKSQKRKYIEIDSDEE 588
S SR ++ + +R +A+ RK+ + APG K + DEE
Sbjct: 177 NVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEE 226
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/260 (19%), Positives = 110/260 (42%), Gaps = 17/260 (6%)
Query: 428 VMMSARTLIHLFR--------TLNPQMLQKKFRGKPTEASIEARVQEYGELDAKDYIPGA 479
V+ RT +H + T P+ + K F + T ++ + +E L+ A
Sbjct: 488 VVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEA 547
Query: 480 EVLEVEKEENAENDEDGWESTSLSEEEDADGEWID---VQHSSDEEQQEISKKLNSMPME 536
E L +K E E+ E L EE V+ +E++++I +K + +
Sbjct: 548 EQLRRQKVE--EDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEK 605
Query: 537 ERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSL 596
KAK ++ + + +K+ + R++ + ++++ ++++ + +E ELL
Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE---EARRLRWLQQEEEERRHQELLQK 662
Query: 597 RDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRY 656
+ E + K+ + RLA + +E ++ + +E+++Q R
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 722
Query: 657 SQNVRSKNKRSFREKQLALR 676
Q R + +R +E++ ALR
Sbjct: 723 EQE-RLQAERELQEREKALR 741
Score = 33.1 bits (74), Expect = 0.88
Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 17/179 (9%)
Query: 465 QEYGELDAKDYIPGAEVLEVEKEEN--AENDEDGWESTSLSEEEDADGEWID-------- 514
Q++ ++D K E L EK + A + E+ EEE W+
Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656
Query: 515 ---VQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRV---LTQEDFQKIRMAQMRKEL 568
+Q +EEQ+ + K + + E++ + R QE ++ R Q R+
Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 716
Query: 569 DAAPGKSQKRKYIEIDSDEEPRGELLSLRDIER-LHKKPKSDKETRLATAMAGKTDRKE 626
+ + Q+R E + E + L ++R L +K K +++ RLA + K+
Sbjct: 717 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKK 775
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/281 (20%), Positives = 113/281 (40%), Gaps = 54/281 (19%)
Query: 454 KPTEASIEARVQEYGEL-----DAKDYIPGAEVLEVEKEENAENDEDGWESTS------- 501
KP E + +A +E E+ +A+ +I A +E E N+ G S S
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAA----IEPESGKSNERKGGRSRSHTRSKSR 317
Query: 502 LSEEEDADGEWIDVQHSS-----------DEEQQEISKKLNSMPMEERKAKAAA------ 544
S + + + +H S D + + K S E RK+++ +
Sbjct: 318 SSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 377
Query: 545 ------ISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRD 598
I + ++D +K R + +E + GK++ R E + D E E R+
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK-EREKDREKDKEKDRERE 436
Query: 599 IERLHKKPKS-------DKETRLATAMAGKTDRKEFVRKKTKTNP-------FSSSTNKE 644
E+ H+K + DKE + + D K KK++T P S S+++E
Sbjct: 437 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 496
Query: 645 KKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKR 685
++++++ R + ++ ++S R R+ KKR++
Sbjct: 497 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 537
Score = 34.7 bits (78), Expect = 0.30
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 9/169 (5%)
Query: 483 EVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKA 542
E EK+ + ++D E+D D E Q E +++ SK+++ +++K++
Sbjct: 420 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 479
Query: 543 AAISTSRVLTQEDFQKIRMAQMRKELDAAP--GKSQKRKYIEIDSDEEPRGELLSLRDIE 600
S + + R + + +P K+ KRK S R + R+ E
Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS-RNKKDKKREKE 538
Query: 601 RLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQK 649
R H + ++E +T+M ++ ++ K K +S++ KEK+ K
Sbjct: 539 RDHISERRERER--STSMRKSSNDRDGKEKLEK----NSTSLKEKEHNK 581
Score = 33.9 bits (76), Expect = 0.52
Identities = 44/213 (20%), Positives = 84/213 (39%), Gaps = 24/213 (11%)
Query: 471 DAKDYIPGAE-VLEVEKEENAENDEDGWESTSLSEEEDADGEWI-DVQHSSDEEQQEISK 528
D ++ I E V E ++E+ E +++ + + +D D E D + +++++ +
Sbjct: 379 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 438
Query: 529 KLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEE 588
K + ++ K K ++D +K R KE+D K +K + +
Sbjct: 439 KEHEKDRDKEKEK-----------EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 487
Query: 589 PRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVR---KKTKTNPFSSSTNKEK 645
R S R + S + R + + K+ R R KK K E+
Sbjct: 488 RRSRSSSRE--RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 545
Query: 646 KKQKNFMMMRYSQNVR------SKNKRSFREKQ 672
++++ MR S N R KN S +EK+
Sbjct: 546 RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 578
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/281 (20%), Positives = 113/281 (40%), Gaps = 54/281 (19%)
Query: 454 KPTEASIEARVQEYGEL-----DAKDYIPGAEVLEVEKEENAENDEDGWESTS------- 501
KP E + +A +E E+ +A+ +I A +E E N+ G S S
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAA----IEPESGKSNERKGGRSRSHTRSKSR 201
Query: 502 LSEEEDADGEWIDVQHSS-----------DEEQQEISKKLNSMPMEERKAKAAA------ 544
S + + + +H S D + + K S E RK+++ +
Sbjct: 202 SSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKR 261
Query: 545 ------ISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRD 598
I + ++D +K R + +E + GK++ R E + D E E R+
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK-EREKDREKDKEKDRERE 320
Query: 599 IERLHKKPKS-------DKETRLATAMAGKTDRKEFVRKKTKTNP-------FSSSTNKE 644
E+ H+K + DKE + + D K KK++T P S S+++E
Sbjct: 321 REKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRE 380
Query: 645 KKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKR 685
++++++ R + ++ ++S R R+ KKR++
Sbjct: 381 RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREK 421
Score = 34.7 bits (78), Expect = 0.30
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 9/169 (5%)
Query: 483 EVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKA 542
E EK+ + ++D E+D D E Q E +++ SK+++ +++K++
Sbjct: 304 EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRT 363
Query: 543 AAISTSRVLTQEDFQKIRMAQMRKELDAAP--GKSQKRKYIEIDSDEEPRGELLSLRDIE 600
S + + R + + +P K+ KRK S R + R+ E
Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRS-RNKKDKKREKE 422
Query: 601 RLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQK 649
R H + ++E +T+M ++ ++ K K +S++ KEK+ K
Sbjct: 423 RDHISERRERER--STSMRKSSNDRDGKEKLEK----NSTSLKEKEHNK 465
Score = 33.9 bits (76), Expect = 0.52
Identities = 44/213 (20%), Positives = 84/213 (39%), Gaps = 24/213 (11%)
Query: 471 DAKDYIPGAE-VLEVEKEENAENDEDGWESTSLSEEEDADGEWI-DVQHSSDEEQQEISK 528
D ++ I E V E ++E+ E +++ + + +D D E D + +++++ +
Sbjct: 263 DTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERERE 322
Query: 529 KLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEE 588
K + ++ K K ++D +K R KE+D K +K + +
Sbjct: 323 KEHEKDRDKEKEK-----------EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNAS 371
Query: 589 PRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVR---KKTKTNPFSSSTNKEK 645
R S R + S + R + + K+ R R KK K E+
Sbjct: 372 RRSRSSSRE--RRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER 429
Query: 646 KKQKNFMMMRYSQNVR------SKNKRSFREKQ 672
++++ MR S N R KN S +EK+
Sbjct: 430 RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKE 462
>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
[Homo sapiens]
Length = 845
Score = 40.4 bits (93), Expect = 0.006
Identities = 37/173 (21%), Positives = 82/173 (47%), Gaps = 12/173 (6%)
Query: 515 VQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGK 574
+Q S+EE++E +K P + K + ++ +++E ++ + ++E K
Sbjct: 136 IQDQSEEEEEE--EKHPPKPAKPEKNRI-----NKAVSEEQQPALKGKKGKEEKSKGKAK 188
Query: 575 SQKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKT 634
Q K+ +D++EE + E + +++ E + + K+ + G+ + +E ++K
Sbjct: 189 PQN-KFAALDNEEEDKEEEI-IKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKA 246
Query: 635 N-PFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRM 686
+ P++ + KEKKK K M Y + V S + E ++ A + R+ M
Sbjct: 247 DDPYAHLSKKEKKKLKK--QMEYERQVASLKAANAAENDFSVSQAEMSSRQAM 297
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 40.4 bits (93), Expect = 0.006
Identities = 64/281 (22%), Positives = 110/281 (39%), Gaps = 48/281 (17%)
Query: 411 EELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGEL 470
EE++++ K +K+ M A T I T + K+ + + E E E E+
Sbjct: 454 EEIIEET---KVEDEKSEMEEALTAI----TEELAVSMKEEKKEAAEEKEEEPEAEEEEV 506
Query: 471 DAKDYIPGAEVLEVEKEENAENDEDGWES---------TSLSEEEDADGEWIDVQHSSDE 521
AK A EV++EE + +E+G E + +EE ++ E + ++
Sbjct: 507 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 566
Query: 522 EQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDF---QKIRMAQMRK---------ELD 569
E+ E + E ++ K + V T+E+ K+ + K E
Sbjct: 567 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 626
Query: 570 AAP---------GKS--------QKRKYIEIDSDEEPRGEL-LSLRDIERLHKKP--KSD 609
+P GKS +K K S E +G+ +S +E K P KS
Sbjct: 627 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP 686
Query: 610 KETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKN 650
E + A GK ++KE K+ K P K+++K K+
Sbjct: 687 VEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD 727
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 40.4 bits (93), Expect = 0.006
Identities = 64/281 (22%), Positives = 110/281 (39%), Gaps = 48/281 (17%)
Query: 411 EELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGEL 470
EE++++ K +K+ M A T I T + K+ + + E E E E+
Sbjct: 78 EEIIEET---KVEDEKSEMEEALTAI----TEELAVSMKEEKKEAAEEKEEEPEAEEEEV 130
Query: 471 DAKDYIPGAEVLEVEKEENAENDEDGWES---------TSLSEEEDADGEWIDVQHSSDE 521
AK A EV++EE + +E+G E + +EE ++ E + ++
Sbjct: 131 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 190
Query: 522 EQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDF---QKIRMAQMRK---------ELD 569
E+ E + E ++ K + V T+E+ K+ + K E
Sbjct: 191 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 250
Query: 570 AAP---------GKS--------QKRKYIEIDSDEEPRGEL-LSLRDIERLHKKP--KSD 609
+P GKS +K K S E +G+ +S +E K P KS
Sbjct: 251 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSP 310
Query: 610 KETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKN 650
E + A GK ++KE K+ K P K+++K K+
Sbjct: 311 VEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKD 351
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 40.0 bits (92), Expect = 0.007
Identities = 37/176 (21%), Positives = 81/176 (46%), Gaps = 10/176 (5%)
Query: 479 AEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNS----MP 534
A++ V + +++ D ES SL +EE E + +E+Q+ S+K+ S M
Sbjct: 207 AQIDPVLLKNSSQQDNSSRESPSLEDEETKKEE-----ETPKQEEQKESEKMKSEEQPMD 261
Query: 535 MEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELL 594
+E R T+ +ED +++ + +L+ +++++K I+ +SD
Sbjct: 262 LENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFKENVKP 321
Query: 595 SLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKN 650
+++ PK D ++ + +A + +R EF ++ + + +E +K KN
Sbjct: 322 IKVEVKECRADPK-DTKSSMEKPVAQEPERIEFGGNIKSSHEITEKSTEETEKLKN 376
Score = 39.3 bits (90), Expect = 0.012
Identities = 44/205 (21%), Positives = 82/205 (40%), Gaps = 21/205 (10%)
Query: 462 ARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDE 521
A +E E + + G V +V+ E E+ E + + ++A I+ +
Sbjct: 642 ASEKEVVECQSTSTVGGQSVKKVDLETLKEDSE--FTKVEMDNLDNAQTSGIEEPSETKG 699
Query: 522 EQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQ-KRKY 580
Q+ K +P EE A TS + IR++ +K+ D+ P + + K
Sbjct: 700 SMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEPENKQ 759
Query: 581 IEIDSDEE----------------PRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDR 624
+ + +EE P ++ +RD + K+ + + E + KTD+
Sbjct: 760 EKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDK 819
Query: 625 KEFVRKKTKTNPFSSSTNKEKKKQK 649
KE ++K K +S +K K K K
Sbjct: 820 KEILKKSEKDT--NSKVSKVKPKGK 842
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 40.0 bits (92), Expect = 0.007
Identities = 97/476 (20%), Positives = 182/476 (38%), Gaps = 95/476 (19%)
Query: 228 EKQDSDSESEDDGPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAI 287
EK ++ + ED PT + S KK++K K LKK K K K
Sbjct: 595 EKSNAKIKDEDHSPTFEN----------SDCTLKKMDKEGKTLKKHKLKHKERE------ 638
Query: 288 HLIHDPQDFAEKLLKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQ 347
EK K++E KE+++ K L + E + NF+
Sbjct: 639 ---------KEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFK---------S 680
Query: 348 REVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKE----ITA 403
E + L S L ++ N DK++ E KE I
Sbjct: 681 DETEDLFLNMEHESLTLEKKSKLEK-------NIKDDKSTKEKHVSKERNFKEERDKIKK 733
Query: 404 RCPLAMTEELLQDLAQYKTH--KDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIE 461
+ EE ++DL + + + DK+ ++ + + ++ +++K+ + E I+
Sbjct: 734 ESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIK 793
Query: 462 A---RVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDAD-GEWIDVQH 517
+ ++ ++ KD I E EKE+ +++ SE++ D E +D
Sbjct: 794 ESKEKPEKRSQIKEKD-IEKMERKTFEKEKKIKHEHK-------SEKDKLDLSECVDKIK 845
Query: 518 SSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQ- 576
D+ ++K + E K+K +T+ + +D +K R RK P K +
Sbjct: 846 EKDKLYSHHTEKCHK---EGEKSK----NTAAIKKTDDREKSREKMDRKHDKEKPEKERH 898
Query: 577 ----------KRKYIEIDSDEEPRGELLSLRDIER-LHKKPKS----------------D 609
++K + D+ E + E ++ +R L KK KS +
Sbjct: 899 LAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEE 958
Query: 610 KETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNK 665
K++ + + ++ +++KTK P + KEK K K+ + RY + + K+K
Sbjct: 959 KKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDK-KDKDIDRYKERDKHKDK 1013
Score = 39.3 bits (90), Expect = 0.012
Identities = 44/201 (21%), Positives = 78/201 (38%), Gaps = 30/201 (14%)
Query: 485 EKEENAENDEDG-WESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAA 543
E+ EN D+D + S +S E++ G + + E+Q++ K+ P + + K
Sbjct: 749 EERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIK-- 806
Query: 544 AISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDS--DEEPRGELLSLRDIER 601
++D +K+ KE ++ +++ D+ + L E+
Sbjct: 807 ---------EKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEK 857
Query: 602 LHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEK------------KKQK 649
HK+ + K TA KTD +E R+K KE+ KK K
Sbjct: 858 CHKEGEKSKN----TAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNK 913
Query: 650 NFMMMRYSQNVRSKNKRSFRE 670
YS++ + KNK RE
Sbjct: 914 QSDNSEYSKSEKGKNKEKDRE 934
Score = 30.0 bits (66), Expect = 7.4
Identities = 44/221 (19%), Positives = 93/221 (42%), Gaps = 28/221 (12%)
Query: 456 TEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDV 515
+E S++ + Y +++ + V + +E +++ +D L E ++ + D
Sbjct: 549 SEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKD----FHLEFGEKSNAKIKDE 604
Query: 516 QHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKS 575
HS E + + L M E + K K++ + KE +
Sbjct: 605 DHSPTFENSDCT--LKKMDKEGKTLKK--------------HKLKHKEREKEKHKKEIEG 648
Query: 576 QKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKT---DRKEFVRKKT 632
+K KY DS +E + + R+ + KSD+ L M ++ ++K + K
Sbjct: 649 EKEKYKTKDSAKELQRSVEFDREFWK-ENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI 707
Query: 633 KTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQL 673
K + S+ K K++NF R ++ ++++SFRE+++
Sbjct: 708 KDD--KSTKEKHVSKERNFKEER--DKIKKESEKSFREEKI 744
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 40.0 bits (92), Expect = 0.007
Identities = 97/476 (20%), Positives = 182/476 (38%), Gaps = 95/476 (19%)
Query: 228 EKQDSDSESEDDGPTARDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAI 287
EK ++ + ED PT + S KK++K K LKK K K K
Sbjct: 618 EKSNAKIKDEDHSPTFEN----------SDCTLKKMDKEGKTLKKHKLKHKERE------ 661
Query: 288 HLIHDPQDFAEKLLKQLECCKERFEVKMMLMNLISRLVGIHELFLFNFYPFLQRFLQPHQ 347
EK K++E KE+++ K L + E + NF+
Sbjct: 662 ---------KEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFK---------S 703
Query: 348 REVTKILLFAAQASHHLVPPEIIQSLLMTVANNFVTDKNSGEVMTVGINAIKE----ITA 403
E + L S L ++ N DK++ E KE I
Sbjct: 704 DETEDLFLNMEHESLTLEKKSKLEK-------NIKDDKSTKEKHVSKERNFKEERDKIKK 756
Query: 404 RCPLAMTEELLQDLAQYKTH--KDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIE 461
+ EE ++DL + + + DK+ ++ + + ++ +++K+ + E I+
Sbjct: 757 ESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIK 816
Query: 462 A---RVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDAD-GEWIDVQH 517
+ ++ ++ KD I E EKE+ +++ SE++ D E +D
Sbjct: 817 ESKEKPEKRSQIKEKD-IEKMERKTFEKEKKIKHEHK-------SEKDKLDLSECVDKIK 868
Query: 518 SSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQ- 576
D+ ++K + E K+K +T+ + +D +K R RK P K +
Sbjct: 869 EKDKLYSHHTEKCHK---EGEKSK----NTAAIKKTDDREKSREKMDRKHDKEKPEKERH 921
Query: 577 ----------KRKYIEIDSDEEPRGELLSLRDIER-LHKKPKS----------------D 609
++K + D+ E + E ++ +R L KK KS +
Sbjct: 922 LAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEE 981
Query: 610 KETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNK 665
K++ + + ++ +++KTK P + KEK K K+ + RY + + K+K
Sbjct: 982 KKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDK-KDKDIDRYKERDKHKDK 1036
Score = 39.3 bits (90), Expect = 0.012
Identities = 44/201 (21%), Positives = 78/201 (38%), Gaps = 30/201 (14%)
Query: 485 EKEENAENDEDG-WESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAA 543
E+ EN D+D + S +S E++ G + + E+Q++ K+ P + + K
Sbjct: 772 EERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIK-- 829
Query: 544 AISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDS--DEEPRGELLSLRDIER 601
++D +K+ KE ++ +++ D+ + L E+
Sbjct: 830 ---------EKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEK 880
Query: 602 LHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEK------------KKQK 649
HK+ + K TA KTD +E R+K KE+ KK K
Sbjct: 881 CHKEGEKSKN----TAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNK 936
Query: 650 NFMMMRYSQNVRSKNKRSFRE 670
YS++ + KNK RE
Sbjct: 937 QSDNSEYSKSEKGKNKEKDRE 957
Score = 30.0 bits (66), Expect = 7.4
Identities = 44/221 (19%), Positives = 93/221 (42%), Gaps = 28/221 (12%)
Query: 456 TEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDV 515
+E S++ + Y +++ + V + +E +++ +D L E ++ + D
Sbjct: 572 SEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKD----FHLEFGEKSNAKIKDE 627
Query: 516 QHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKS 575
HS E + + L M E + K K++ + KE +
Sbjct: 628 DHSPTFENSDCT--LKKMDKEGKTLKK--------------HKLKHKEREKEKHKKEIEG 671
Query: 576 QKRKYIEIDSDEEPRGELLSLRDIERLHKKPKSDKETRLATAMAGKT---DRKEFVRKKT 632
+K KY DS +E + + R+ + KSD+ L M ++ ++K + K
Sbjct: 672 EKEKYKTKDSAKELQRSVEFDREFWK-ENFFKSDETEDLFLNMEHESLTLEKKSKLEKNI 730
Query: 633 KTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQL 673
K + S+ K K++NF R ++ ++++SFRE+++
Sbjct: 731 KDD--KSTKEKHVSKERNFKEER--DKIKKESEKSFREEKI 767
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 40.0 bits (92), Expect = 0.007
Identities = 44/202 (21%), Positives = 92/202 (45%), Gaps = 14/202 (6%)
Query: 480 EVLEVEKEENAENDEDG--WESTSLSEEEDADGEWIDVQHSS---DEEQQEISKKLNSMP 534
E E++ EE + E+ + L +EE E ++H S ++ +Q++ + +
Sbjct: 63 EQFELDMEEAIQKAEENKRLKELQLKQEEKLAMELAKLKHESLKDEKMRQQVRENSIELR 122
Query: 535 MEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYI--EIDSDEEPRGE 592
E+K KAA ++ R + I+ QM+++ + A ++ K I E ++ E+ R +
Sbjct: 123 ELEKKLKAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKEENAAEDKRNK 182
Query: 593 LLS--LRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKN 650
+ D+E+ ++ + K+ + K E VRK + K++K +K
Sbjct: 183 AKAQYYLDLEKQLEEQEKKKQEAYEQLLKEKLMIDEIVRKIYE----EDQLEKQQKLEKM 238
Query: 651 FMMMRYSQNVRSKNKRSFREKQ 672
M RY + + K + +R+K+
Sbjct: 239 NAMRRYIEEFQ-KEQALWRKKK 259
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 39.7 bits (91), Expect = 0.009
Identities = 56/227 (24%), Positives = 102/227 (44%), Gaps = 44/227 (19%)
Query: 485 EKEENAENDED-GWESTSLSEEED--ADGEWIDVQHSS---------DEEQQEISKKLNS 532
EK++ AE +E W+ LSEEE A E + +Q EE++ + +K
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQ 1804
Query: 533 MPMEERKAKAAA-----ISTSRVLTQED---FQKIRMAQMRKELDAAPGKSQKRKYIEID 584
+ E+K K A I++ LT+ +QK +AQ +K L K +RK +
Sbjct: 1805 --LIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLY 1862
Query: 585 SDE---EPRGELLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSST 641
+ E + +L+ +++ + K + E +L T KE V KK
Sbjct: 1863 NKERLTHSKKQLVQVKNKLGMFNKILAQVEEKL-------TQEKETVIKK---------- 1905
Query: 642 NKEKKKQKNFMMMRYSQNVRSKNKRSFREK-QLALRDALLKKRKRMK 687
KEK + +++ ++ K ++ +EK +LAL A+++ +KR++
Sbjct: 1906 -KEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLR 1951
Score = 35.4 bits (80), Expect = 0.18
Identities = 31/147 (21%), Positives = 60/147 (40%), Gaps = 12/147 (8%)
Query: 448 QKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEED 507
++KF + E E E E D + E L E+EE E +E+ E EEE+
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEME-SLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE 2268
Query: 508 ADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKE 567
E + ++E++E KK EE + K +E F++ +E
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK-----------EEVFEEKEEIMSEEE 2317
Query: 568 LDAAPGKSQKRKYIEIDSDEEPRGELL 594
++ + ++ + ++ + + E+L
Sbjct: 2318 TESLSDEEEEEESCSLEEEVDREKEIL 2344
Score = 31.2 bits (69), Expect = 3.3
Identities = 38/195 (19%), Positives = 80/195 (41%), Gaps = 21/195 (10%)
Query: 480 EVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERK 539
E + +E+E + E +E + T + +W + +++ +++ + EE K
Sbjct: 1542 EEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK 1601
Query: 540 AKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDI 599
R L QE+ +K+ A ++ D + K+ + + RGE LS ++
Sbjct: 1602 ----LAQEERQLAQEE-RKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS-QEA 1655
Query: 600 ERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQN 659
E+L +K K +LA +E + KK + + KN + + +
Sbjct: 1656 EKLAQKRK-----KLAKKWEKVAREEEKLAKK----------GGKLAEVKNILAQKVEEL 1700
Query: 660 VRSKNKRSFREKQLA 674
+ + ++EK+LA
Sbjct: 1701 PQREQNLDWQEKELA 1715
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 39.3 bits (90), Expect = 0.012
Identities = 52/269 (19%), Positives = 105/269 (39%), Gaps = 36/269 (13%)
Query: 448 QKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEED 507
QK+F T+AS+ + A++ E ++E E +E + S + +
Sbjct: 112 QKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW 171
Query: 508 ADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQED---FQKIRMAQM 564
D E + EE++E K S+ + + K + R QED F+K +
Sbjct: 172 RDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE 231
Query: 565 RKELDAAPGKS------QKRKYIEIDSDEEPRGELLS--LRDIERLHKKP---------- 606
+ + D P + +K+ + E+ S GE ++ L+ E +P
Sbjct: 232 KIKKDKEPKEEVKSFMDRKKGFTEVKSQN---GEFMTHKLKHTENTFSRPGGRASVDTKE 288
Query: 607 -------KSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQN 659
++ K G+T+ +EF + K K + + KKK++ + +
Sbjct: 289 AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 348
Query: 660 VRSKNKRSFR-----EKQLALRDALLKKR 683
R K + + R E++ L++ + ++R
Sbjct: 349 QRRKQEEADRKLREEEEKRRLKEEIERRR 377
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 39.3 bits (90), Expect = 0.012
Identities = 52/269 (19%), Positives = 105/269 (39%), Gaps = 36/269 (13%)
Query: 448 QKKFRGKPTEASIEARVQEYGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEED 507
QK+F T+AS+ + A++ E ++E E +E + S + +
Sbjct: 118 QKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDW 177
Query: 508 ADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAKAAAISTSRVLTQED---FQKIRMAQM 564
D E + EE++E K S+ + + K + R QED F+K +
Sbjct: 178 RDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDE 237
Query: 565 RKELDAAPGKS------QKRKYIEIDSDEEPRGELLS--LRDIERLHKKP---------- 606
+ + D P + +K+ + E+ S GE ++ L+ E +P
Sbjct: 238 KIKKDKEPKEEVKSFMDRKKGFTEVKSQN---GEFMTHKLKHTENTFSRPGGRASVDTKE 294
Query: 607 -------KSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQN 659
++ K G+T+ +EF + K K + + KKK++ + +
Sbjct: 295 AEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEE 354
Query: 660 VRSKNKRSFR-----EKQLALRDALLKKR 683
R K + + R E++ L++ + ++R
Sbjct: 355 QRRKQEEADRKLREEEEKRRLKEEIERRR 383
>gi|146260271 hypothetical protein LOC129881 [Homo sapiens]
Length = 552
Score = 39.3 bits (90), Expect = 0.012
Identities = 67/310 (21%), Positives = 120/310 (38%), Gaps = 39/310 (12%)
Query: 409 MTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQE-- 466
+T E A+ K K+ + + S + H T QK K + IEA Q
Sbjct: 65 LTREAACLRAERKAKKEMH-LRSQEVVKHWTNTYAGMKEQKLEAKKKRDEEIEAERQILD 123
Query: 467 -----YGELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDE 521
Y + K I A+ + + E +N G + + +E DA E+ + SD+
Sbjct: 124 LEEEIYKQGKRKKAIENAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFRKSKIKSDK 183
Query: 522 EQQEISKKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYI 581
+ +E K +E + KA RV +D K ++ + +E + +++KY
Sbjct: 184 KWEEQLKLNIEKAFKEEQEKAEKRHRERVALAKDHLK-QIKEHEEE------EERRKKYE 236
Query: 582 EIDSDEEPR-GELLSLRDIERLHKKPK-------------SDKETRLATAMAGKTDRKEF 627
E D++E R L + ++L KK + DK A + + E
Sbjct: 237 EKDAEEIKRQNALYEIEMRKKLEKKREEMHESRRRFLEHMQDKHIIKAVEQQQQEEEDEK 296
Query: 628 VRKKTKTNPFSSSTNKEKKKQKNFMMMRYSQNVRSKNKRSFREK----------QLALRD 677
+RK K KEK+ + + +M + + + + +EK +A +
Sbjct: 297 MRKFIKAKKRLIQMGKEKEAETHRLMEKRRERIHNFLSELLKEKLDNEDMIIARDIAEAE 356
Query: 678 ALLKKRKRMK 687
A +KR+R K
Sbjct: 357 AEWEKREREK 366
>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
Length = 1531
Score = 38.9 bits (89), Expect = 0.016
Identities = 42/191 (21%), Positives = 86/191 (45%), Gaps = 15/191 (7%)
Query: 482 LEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEERKAK 541
L EKE+ + + S E+ E ++ + +++ +++ +P + KAK
Sbjct: 1147 LRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVG-----LPGKGGKAK 1201
Query: 542 AAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDI-E 600
+ VL Q++ + ++ E+ A K K+K +++ P+ + + L + +
Sbjct: 1202 GKKTQMAEVLPSPRGQRV-IPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGVELEGLKQ 1260
Query: 601 RLHKKPKSDK--ETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNF-MMMRYS 657
RL KK K + +T+ T +A K ++K K NP+S S + + NF + R +
Sbjct: 1261 RLEKKQKREPGTKTKKQTTLAFKP-----IKKGKKRNPWSDSESDRSSDESNFDVPPRET 1315
Query: 658 QNVRSKNKRSF 668
+ R+ K F
Sbjct: 1316 EPRRAATKTKF 1326
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 38.5 bits (88), Expect = 0.021
Identities = 39/210 (18%), Positives = 85/210 (40%), Gaps = 2/210 (0%)
Query: 479 AEVLEVEKE-ENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNSMPMEE 537
+E+ E E+E E + + ES E + + + + E+ + KK EE
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKK-GERKKEE 94
Query: 538 RKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLR 597
R+ K +E ++ + + + + GK ++RK + + R R
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 598 DIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRYS 657
+ ER K+ K + ++ + +++ RKK + N +E+K+++ R
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 658 QNVRSKNKRSFREKQLALRDALLKKRKRMK 687
+ R K ++ R+ ++ ++RK K
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 32.3 bits (72), Expect = 1.5
Identities = 32/147 (21%), Positives = 64/147 (43%), Gaps = 14/147 (9%)
Query: 548 SRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLRDIERLHKKPK 607
S+ TQ +Q + + +E++ + + +K E + +E R R+ E+ K+ +
Sbjct: 26 SKPCTQPGWQS-EIREREREIET---RKEGKKERESERKKERREREKRKREREKERKRER 81
Query: 608 SDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFM-------MMRYSQNV 660
KE + K +R+ R++ K N K KKK+K R +
Sbjct: 82 GKKEKK---GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE 138
Query: 661 RSKNKRSFREKQLALRDALLKKRKRMK 687
R + +R RE++ R+ ++++R K
Sbjct: 139 RKREERKERERKKEEREKERERKERKK 165
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 38.5 bits (88), Expect = 0.021
Identities = 48/288 (16%), Positives = 121/288 (42%), Gaps = 16/288 (5%)
Query: 408 AMTEELLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEY 467
A++ EL ++ + K KN + + + Q+ K+ + K A +
Sbjct: 170 ALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQT 229
Query: 468 GELDAKDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEIS 527
L + + E+ E EK+ + ++ + L E+E E + ++ +E
Sbjct: 230 NTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQE 289
Query: 528 KKLNSMPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDE 587
K+L E R+ K ++ QE+ +M + +++ K +++ + ++
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEE----KMWEQEEKMREQEEKMWRQEERLWEQEK 345
Query: 588 EPRGELLSLRD--------IERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSS 639
+ R + +RD ERL +K + +E K +E +R++ K
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
Query: 640 STNKEKKKQKNFMMMRYSQNVRSKNKRSFREKQLALRDALLKKRKRMK 687
T +E++++ M + +N+ + ++ +++++L + L ++++M+
Sbjct: 406 ETMREQEEK----MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Score = 36.2 bits (82), Expect = 0.10
Identities = 38/196 (19%), Positives = 89/196 (45%), Gaps = 17/196 (8%)
Query: 480 EVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDE--EQQEISKKLNSMPMEE 537
E ++ ++E E +E W+ L E+++ E +Q ++ EQ+E + M +E
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 472
Query: 538 RKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGELLSLR 597
+K ++ QED Q + ++ + ++R + + DE R + +R
Sbjct: 473 KKMWRQ----EKMREQED-QMWEQEEKMRDQEQKMWDQEERMW---EQDERLREKEERMR 524
Query: 598 DIERLHKKPKSDKETRLATAMAGKT-DRKEFVRKKTKTNPFSSSTNKEKKKQKNFMMMRY 656
+ +++ ++ + +E + KT D++E +R++ + +EKK ++ MMR
Sbjct: 525 EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR------EREKKMREEEEMMRE 578
Query: 657 SQNVRSKNKRSFREKQ 672
+ + + RE++
Sbjct: 579 QEEKMQEQEEKMREQE 594
Score = 35.4 bits (80), Expect = 0.18
Identities = 41/204 (20%), Positives = 79/204 (38%), Gaps = 13/204 (6%)
Query: 485 EKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKL-----NSMPMEERK 539
EKEE E WE +EE+ E +E +E +K+ N EE++
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 429
Query: 540 AKAAAISTSR------VLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGEL 593
+ + + QE +KI Q K D Q++K + E ++
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKI-WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 488
Query: 594 LSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFMM 653
+ R ++ D+E R+ +++E +R++ K +EKK Q+
Sbjct: 489 WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ-EK 547
Query: 654 MRYSQNVRSKNKRSFREKQLALRD 677
+ Q + + + RE++ +R+
Sbjct: 548 KTWDQEEKMREEERMREREKKMRE 571
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 38.5 bits (88), Expect = 0.021
Identities = 52/264 (19%), Positives = 107/264 (40%), Gaps = 23/264 (8%)
Query: 413 LLQDLAQYKTHKDKNVMMSARTLIHLFRTLNPQMLQKKFRGKPTEASIEARVQEYGELDA 472
L+ L + V+ R L LN L+ +++S E E EL
Sbjct: 479 LISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELK- 537
Query: 473 KDYIPGAEVLEVEKEENAENDEDGWESTSLSEEEDADGEWIDVQHSSDEEQQEISKKLNS 532
P +E L + + + ED E S +EE+ + E + + + E+++ ++
Sbjct: 538 ----PDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKERERE 593
Query: 533 MPMEERKAKAAAISTSRVLTQEDFQKIRMAQMRKELDAAPGKSQKRKYIEIDSDEEPRGE 592
+ K + + + D + + A++ K+L IE+ +E + E
Sbjct: 594 KQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLK-----------IELKKAQESQKE 642
Query: 593 LLSLRDIERLHKKPKSDKETRLATAMAGKTDRKEFVRKKTKTNPFSSSTNKEKKKQKNFM 652
+ L D+ R K + DK +A K + ++ +R++ K +KEKK+ K
Sbjct: 643 MKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELED-LRQRLK-----DLEDKEKKENKKMA 696
Query: 653 MMRYSQNVRSKNKR-SFREKQLAL 675
+ +R+ ++ + +K+LA+
Sbjct: 697 DEDALRKIRAVEEQIEYLQKKLAM 720
Score = 31.2 bits (69), Expect = 3.3
Identities = 20/77 (25%), Positives = 39/77 (50%)
Query: 244 RDLLVQYATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFAEKLLKQ 303
RD + A KKS + L + +K L+ ++KK+ ++ + A+ I ++ E L K+
Sbjct: 658 RDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKK 717
Query: 304 LECCKERFEVKMMLMNL 320
L K+ E + M++
Sbjct: 718 LAMAKQEEEALLSEMDV 734
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,092,701
Number of Sequences: 37866
Number of extensions: 1075452
Number of successful extensions: 9922
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 367
Number of HSP's that attempted gapping in prelim test: 7548
Number of HSP's gapped (non-prelim): 2106
length of query: 687
length of database: 18,247,518
effective HSP length: 109
effective length of query: 578
effective length of database: 14,120,124
effective search space: 8161431672
effective search space used: 8161431672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.