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Search of human proteins with 150456424
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150456424 RW1 protein [Homo sapiens]
(1883 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150456424 RW1 protein [Homo sapiens] 3762 0.0
gi|187608809 hypothetical protein LOC23240 isoform 2 [Homo sapiens] 254 6e-67
gi|196114949 hypothetical protein LOC23240 isoform 1 [Homo sapiens] 254 6e-67
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 68 1e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 68 1e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 64 1e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 64 1e-09
gi|45827755 transforming, acidic coiled-coil containing protein ... 60 2e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 60 3e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 59 6e-08
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 58 1e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 56 3e-07
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 55 5e-07
gi|150418009 transforming, acidic coiled-coil containing protein... 55 6e-07
gi|45827753 transforming, acidic coiled-coil containing protein ... 55 6e-07
gi|11119414 transforming, acidic coiled-coil containing protein ... 55 6e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 55 8e-07
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 55 8e-07
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 55 8e-07
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 54 1e-06
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 54 1e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 53 2e-06
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 52 4e-06
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 52 4e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 4e-06
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 52 7e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 51 9e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 51 9e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 51 1e-05
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 51 1e-05
>gi|150456424 RW1 protein [Homo sapiens]
Length = 1883
Score = 3762 bits (9756), Expect = 0.0
Identities = 1883/1883 (100%), Positives = 1883/1883 (100%)
Query: 1 MGKRAGGGATGATTAAVSTSAGAGLEPAAARSGGPRSAAAGLLGALHLVMTLVVAAARAE 60
MGKRAGGGATGATTAAVSTSAGAGLEPAAARSGGPRSAAAGLLGALHLVMTLVVAAARAE
Sbjct: 1 MGKRAGGGATGATTAAVSTSAGAGLEPAAARSGGPRSAAAGLLGALHLVMTLVVAAARAE 60
Query: 61 KEAFVQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQ 120
KEAFVQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQ
Sbjct: 61 KEAFVQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQ 120
Query: 121 PVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVV 180
PVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVV
Sbjct: 121 PVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVV 180
Query: 181 GNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPL 240
GNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPL
Sbjct: 181 GNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPL 240
Query: 241 QVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTN 300
QVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTN
Sbjct: 241 QVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTN 300
Query: 301 ASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSV 360
ASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSV
Sbjct: 301 ASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSV 360
Query: 361 RPTPQNDAITVHFKPITLKASESKYTKVASISFDASKAKKPSQFSGKITVKAKEKSYSKL 420
RPTPQNDAITVHFKPITLKASESKYTKVASISFDASKAKKPSQFSGKITVKAKEKSYSKL
Sbjct: 361 RPTPQNDAITVHFKPITLKASESKYTKVASISFDASKAKKPSQFSGKITVKAKEKSYSKL 420
Query: 421 EIPYQAEVLDGYLGFDHAATLFHIRDSPADPVERPIYLTNTFSFAILIHDVLLPEEAKTM 480
EIPYQAEVLDGYLGFDHAATLFHIRDSPADPVERPIYLTNTFSFAILIHDVLLPEEAKTM
Sbjct: 421 EIPYQAEVLDGYLGFDHAATLFHIRDSPADPVERPIYLTNTFSFAILIHDVLLPEEAKTM 480
Query: 481 FKVHNFSKPVLILPNESGYIFTLLFMPSTSSMHIDNNILLITNASKFHLPVRVYTGFLDY 540
FKVHNFSKPVLILPNESGYIFTLLFMPSTSSMHIDNNILLITNASKFHLPVRVYTGFLDY
Sbjct: 481 FKVHNFSKPVLILPNESGYIFTLLFMPSTSSMHIDNNILLITNASKFHLPVRVYTGFLDY 540
Query: 541 FVLPPKIEERFIDFGVLSATEASNILFAIINSNPIELAIKSWHIIGDGLSIELVAVERGN 600
FVLPPKIEERFIDFGVLSATEASNILFAIINSNPIELAIKSWHIIGDGLSIELVAVERGN
Sbjct: 541 FVLPPKIEERFIDFGVLSATEASNILFAIINSNPIELAIKSWHIIGDGLSIELVAVERGN 600
Query: 601 RTTIISSLPEFEKSSLSDQSSVTLASGYFAVFRVKLTAKKLEGIHDGAIQITTDYEILTI 660
RTTIISSLPEFEKSSLSDQSSVTLASGYFAVFRVKLTAKKLEGIHDGAIQITTDYEILTI
Sbjct: 601 RTTIISSLPEFEKSSLSDQSSVTLASGYFAVFRVKLTAKKLEGIHDGAIQITTDYEILTI 660
Query: 661 PVKAVIAVGSLTCFPKHVVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYK 720
PVKAVIAVGSLTCFPKHVVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYK
Sbjct: 661 PVKAVIAVGSLTCFPKHVVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYK 720
Query: 721 RLRGNKEDLEPGKKSKIANIYFDPGLQCGDHCYVGLPFLSKSEPKVQPGVAMQEDMWDAD 780
RLRGNKEDLEPGKKSKIANIYFDPGLQCGDHCYVGLPFLSKSEPKVQPGVAMQEDMWDAD
Sbjct: 721 RLRGNKEDLEPGKKSKIANIYFDPGLQCGDHCYVGLPFLSKSEPKVQPGVAMQEDMWDAD 780
Query: 781 WDLHQSLFKGWTGIKENSGHRLSAIFEVNTDLQKNIISKITAELSWPSILSSPRHLKFPL 840
WDLHQSLFKGWTGIKENSGHRLSAIFEVNTDLQKNIISKITAELSWPSILSSPRHLKFPL
Sbjct: 781 WDLHQSLFKGWTGIKENSGHRLSAIFEVNTDLQKNIISKITAELSWPSILSSPRHLKFPL 840
Query: 841 TNTNCSSEEEITLENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRTLEF 900
TNTNCSSEEEITLENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRTLEF
Sbjct: 841 TNTNCSSEEEITLENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRTLEF 900
Query: 901 QVFRNSAHPLQSSTGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNL 960
QVFRNSAHPLQSSTGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNL
Sbjct: 901 QVFRNSAHPLQSSTGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNL 960
Query: 961 TVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFK 1020
TVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFK
Sbjct: 961 TVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFK 1020
Query: 1021 VENTGQLQIHIETIEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRE 1080
VENTGQLQIHIETIEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRE
Sbjct: 1021 VENTGQLQIHIETIEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRE 1080
Query: 1081 LKFITTSGSEFVFILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAY 1140
LKFITTSGSEFVFILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAY
Sbjct: 1081 LKFITTSGSEFVFILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAY 1140
Query: 1141 LEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAG 1200
LEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAG
Sbjct: 1141 LEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAG 1200
Query: 1201 GSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKT 1260
GSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKT
Sbjct: 1201 GSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKT 1260
Query: 1261 SPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPER 1320
SPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPER
Sbjct: 1261 SPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPER 1320
Query: 1321 LSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKS 1380
LSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKS
Sbjct: 1321 LSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKS 1380
Query: 1381 KGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKE 1440
KGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKE
Sbjct: 1381 KGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKE 1440
Query: 1441 DTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRN 1500
DTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRN
Sbjct: 1441 DTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRN 1500
Query: 1501 LPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSP 1560
LPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSP
Sbjct: 1501 LPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSP 1560
Query: 1561 PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSY 1620
PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSY
Sbjct: 1561 PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSY 1620
Query: 1621 SSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSS 1680
SSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSS
Sbjct: 1621 SSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSS 1680
Query: 1681 NKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSK 1740
NKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSK
Sbjct: 1681 NKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSK 1740
Query: 1741 LGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWS 1800
LGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWS
Sbjct: 1741 LGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWS 1800
Query: 1801 TTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLGQTYNPWR 1860
TTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLGQTYNPWR
Sbjct: 1801 TTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLGQTYNPWR 1860
Query: 1861 IWSPTIGRRSSDPWSNSHFPHEN 1883
IWSPTIGRRSSDPWSNSHFPHEN
Sbjct: 1861 IWSPTIGRRSSDPWSNSHFPHEN 1883
>gi|187608809 hypothetical protein LOC23240 isoform 2 [Homo sapiens]
Length = 1609
Score = 254 bits (649), Expect = 6e-67
Identities = 178/547 (32%), Positives = 272/547 (49%), Gaps = 47/547 (8%)
Query: 735 SKIANIYFDPGLQCGDHCYVGLPFLSKSEPKVQPGVAMQEDMWDADWDLHQSLFKGWTGI 794
+K ++ F+ CG H ++G P +++ + W+ D +L L++ W
Sbjct: 492 TKEGSLGFEVIAHCGMHYFMGKS--KAGNPNWNGSLSLDQSTWNVDSELANKLYERWKKY 549
Query: 795 KENSGHRLSAIFEVNTDLQKNIISKITAELSWPSILSSPR-HLKFPLTNTNCSSEEEITL 853
K + + + K + P +++ P L F T + +
Sbjct: 550 KNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATALRSRMIKYFVV 609
Query: 854 ENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRTLEFQVFRNSAHPLQSS 913
+NP+ PV +Q +PL+LY P V L+ R+ + + I+ T EFQ+ +
Sbjct: 610 QNPSSWPVSLQLLPLSLYPKPEALVH-LLHRWFGTDMQMINFTTGEFQLTEACPY----- 663
Query: 914 TGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNLTVMDAVMVQGQGT 973
G SR IL+L L+P E K V V FTP V+SLI++RNNLTV+D + V+G G
Sbjct: 664 LGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVEGFGA 723
Query: 974 TENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFKVENTGQLQIHIET 1033
E L+V G+LPG G SLRFK+ E+ L DC LK + ++ + FKVEN G L I + +
Sbjct: 724 RELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVSS 783
Query: 1034 IEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRELKFITTSGSEFVF 1093
++I+GY+C+GYGF+V++C +F+L N SRDI I+FTPDFT+S VIR+L +T + EF F
Sbjct: 784 LKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADLEFRF 843
Query: 1094 ILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAYLEAQGIWEPFRR- 1152
LN +LP+H+L CA+ +P P+WE + + + +S L VI A+ +AQ I F +
Sbjct: 844 TLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKT 903
Query: 1153 ------RLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAGGSSSRP 1206
S + +N P DV P + + + F G S +
Sbjct: 904 RQRQNASSSSQQNNGPMDVISPHSYK------------------SNCKNFLDTYGPSDK- 944
Query: 1207 SAGSHKQCGPSVHPHSSHSN---RNSADVENVRAKNSSS---TSSRTSAQAASSQSA--- 1257
G K C P P S N R+ A + + K+ S + +TS AASS S
Sbjct: 945 --GRGKNCLPVNTPQSRIQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTE 1002
Query: 1258 -NKTSPL 1263
+TSPL
Sbjct: 1003 EKQTSPL 1009
Score = 150 bits (380), Expect = 9e-36
Identities = 133/511 (26%), Positives = 237/511 (46%), Gaps = 49/511 (9%)
Query: 37 SAAAGLLGALHLVMTLVVAAARAEKEAFVQSESIIEVLRFDDGGLL---QTETTLGL--- 90
+AA LL + V+ A+ +A +++E+ + ++G LL Q ++ GL
Sbjct: 16 AAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGELLLPTQGDSEEGLEEP 75
Query: 91 SSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATT 150
S Q S L+ G + + F+P +LDF Q +G P + ++ +NPS + + + S+ A
Sbjct: 76 SQEQSFSDKLFSG--KGLHFQPSVLDFGIQFLGHPVAKILHAYNPSRDSEVVVNSVFAAA 133
Query: 151 SHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPY 210
HFH R I G TSF ++FL G++E++LFINTS++GV +Y V G+G
Sbjct: 134 GHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVLSYHVSGIGT---- 189
Query: 211 RLRPFLGARVPVNSSFSPIINIH--NPHSEPLQVVEMYSSGGD---LHLELPTGQQGGTR 265
R+ S + N + P + +Q+ +M + + L ++L
Sbjct: 190 -------RRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNKVC 242
Query: 266 KLWEIPPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSS 325
+ + E+ V+R S ++T+ ++ + + +Y +
Sbjct: 243 QQLKGCYLESDDVLRLQMSIM-----VTMENFSKEFEENTQHLLDHLSI-------VYVA 290
Query: 326 TEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLKASESKY 385
T+ + T D +N+++L+SG + I +R Q DA+++ F+P+ L S + +
Sbjct: 291 TDESE-----TSD-DSAVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNF 344
Query: 386 TKVASISFDASKAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIR 445
TK+AS + K S SG I K L+ + V GY D +AT FHI
Sbjct: 345 TKIASFT-----CKATSCDSGIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIE 399
Query: 446 DSPADPVERPIYLTNTFSFAILIHDVLLPEEAKTMFKVHNFSKPVLILPNESGYIFTLLF 505
I+ N F +++++DV L +E K M K+ NF+ P L LP IF+L
Sbjct: 400 THENTSGLWSIWYRNHFDRSVVLNDVFLSKETKHMLKILNFTGP-LFLPPGCWNIFSLKL 458
Query: 506 MPSTSSMHIDNNILLITN-ASKFHLPVRVYT 535
++++ N+ L TN + F +P+++Y+
Sbjct: 459 AVKDIAINLFTNVFLTTNIGAIFAIPLQIYS 489
Score = 33.1 bits (74), Expect = 2.6
Identities = 89/400 (22%), Positives = 134/400 (33%), Gaps = 56/400 (14%)
Query: 1419 DDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPT 1478
++++ T SNP +E +KE + + K ++ K++ L K++P
Sbjct: 1056 EENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPE 1115
Query: 1479 DVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALA 1538
+ P + + P L R+N + +P +N K VD +P +
Sbjct: 1116 NHLPRNSPQYHQPDLPEISRKNNGNNQQVPV--------KNEVDHCENLKKVDTKPSSEK 1167
Query: 1539 KFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLN---ADIFLKQ 1595
K S+E EK P P K + +LQ LN + K
Sbjct: 1168 KIHKTSRE-----DMFSEKQDIPFVEQEDPYRK--KKLQEKREGNLQNLNWSKSRTCRKN 1220
Query: 1596 RQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQ--PNGSKHKLTKAASLPGK 1653
++ P S P + V S S SSD ++ S ++ K A
Sbjct: 1221 KKRGVAPVSRPPEQSDLKLVC----SDFERSELSSDINVRSWCIQESTREVCK-ADAEIA 1275
Query: 1654 NGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNP 1713
+ P GY + P K S+ SS G S V + S G W S+
Sbjct: 1276 SSLPAAQREAEGYYQKPEKKCVDKFCSDS---SSDCGSSSGSVRA----SRGSWGSWSST 1328
Query: 1714 SSPD-----FTPLNSFSAFGNSF---NLTGEVFSKLGLSRS-CNQASQRSWNEFNSGPSY 1764
SS D F G+S + E L LS + CN + NS P Y
Sbjct: 1329 SSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMT------VNSLPQY 1382
Query: 1765 LWESPATDPSPSWPASSGSPTHTATSV-LGNTSGLWSTTP 1803
PS P+ PT L + LW T P
Sbjct: 1383 --------AEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPP 1414
>gi|196114949 hypothetical protein LOC23240 isoform 1 [Homo sapiens]
Length = 1610
Score = 254 bits (649), Expect = 6e-67
Identities = 178/547 (32%), Positives = 272/547 (49%), Gaps = 47/547 (8%)
Query: 735 SKIANIYFDPGLQCGDHCYVGLPFLSKSEPKVQPGVAMQEDMWDADWDLHQSLFKGWTGI 794
+K ++ F+ CG H ++G P +++ + W+ D +L L++ W
Sbjct: 493 TKEGSLGFEVIAHCGMHYFMGKS--KAGNPNWNGSLSLDQSTWNVDSELANKLYERWKKY 550
Query: 795 KENSGHRLSAIFEVNTDLQKNIISKITAELSWPSILSSPR-HLKFPLTNTNCSSEEEITL 853
K + + + K + P +++ P L F T + +
Sbjct: 551 KNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATALRSRMIKYFVV 610
Query: 854 ENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRTLEFQVFRNSAHPLQSS 913
+NP+ PV +Q +PL+LY P V L+ R+ + + I+ T EFQ+ +
Sbjct: 611 QNPSSWPVSLQLLPLSLYPKPEALVH-LLHRWFGTDMQMINFTTGEFQLTEACPY----- 664
Query: 914 TGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNLTVMDAVMVQGQGT 973
G SR IL+L L+P E K V V FTP V+SLI++RNNLTV+D + V+G G
Sbjct: 665 LGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVEGFGA 724
Query: 974 TENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFKVENTGQLQIHIET 1033
E L+V G+LPG G SLRFK+ E+ L DC LK + ++ + FKVEN G L I + +
Sbjct: 725 RELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVSS 784
Query: 1034 IEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRELKFITTSGSEFVF 1093
++I+GY+C+GYGF+V++C +F+L N SRDI I+FTPDFT+S VIR+L +T + EF F
Sbjct: 785 LKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADLEFRF 844
Query: 1094 ILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAYLEAQGIWEPFRR- 1152
LN +LP+H+L CA+ +P P+WE + + + +S L VI A+ +AQ I F +
Sbjct: 845 TLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKT 904
Query: 1153 ------RLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAGGSSSRP 1206
S + +N P DV P + + + F G S +
Sbjct: 905 RQRQNASSSSQQNNGPMDVISPHSYK------------------SNCKNFLDTYGPSDK- 945
Query: 1207 SAGSHKQCGPSVHPHSSHSN---RNSADVENVRAKNSSS---TSSRTSAQAASSQSA--- 1257
G K C P P S N R+ A + + K+ S + +TS AASS S
Sbjct: 946 --GRGKNCLPVNTPQSRIQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTE 1003
Query: 1258 -NKTSPL 1263
+TSPL
Sbjct: 1004 EKQTSPL 1010
Score = 150 bits (379), Expect = 1e-35
Identities = 133/511 (26%), Positives = 238/511 (46%), Gaps = 48/511 (9%)
Query: 37 SAAAGLLGALHLVMTLVVAAARAEKEAFVQSESIIEVLRFDDGGLL---QTETTLGL--- 90
+AA LL + V+ A+ +A +++E+ + ++G LL Q ++ GL
Sbjct: 16 AAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGELLLPTQGDSEEGLEEP 75
Query: 91 SSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATT 150
S Q S L+ G + + F+P +LDF Q +G P + ++ +NPS + + + S+ A
Sbjct: 76 SQEQSFSDKLFSG--KGLHFQPSVLDFGIQFLGHPVAKILHAYNPSRDSEVVVNSVFAAA 133
Query: 151 SHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPY 210
HFH R I G TSF ++FL G++E++LFINTS++GV +Y V G+G
Sbjct: 134 GHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVLSYHVSGIGT---- 189
Query: 211 RLRPFLGARVPVNSSFSPIINIH--NPHSEPLQVVEMYSSGGD---LHLELPTGQQGGTR 265
R+ S + N + P + +Q+ +M + + L ++L
Sbjct: 190 -------RRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNKVC 242
Query: 266 KLWEIPPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSS 325
+ + E+ V+R S ++T+ ++ + + +Y +
Sbjct: 243 QQLKGCYLESDDVLRLQMSIM-----VTMENFSKEFEENTQHLLDHLSI-------VYVA 290
Query: 326 TEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLKASESKY 385
T+ + T D +N+++L+SG + I +R Q DA+++ F+P+ L S + +
Sbjct: 291 TDESE-----TSD-DSAVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNF 344
Query: 386 TKVASISFDASKAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIR 445
TK+AS + A+ S SG I K L+ + V GY D +AT FHI
Sbjct: 345 TKIASFTCKAA----TSCDSGIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIE 400
Query: 446 DSPADPVERPIYLTNTFSFAILIHDVLLPEEAKTMFKVHNFSKPVLILPNESGYIFTLLF 505
I+ N F +++++DV L +E K M K+ NF+ P L LP IF+L
Sbjct: 401 THENTSGLWSIWYRNHFDRSVVLNDVFLSKETKHMLKILNFTGP-LFLPPGCWNIFSLKL 459
Query: 506 MPSTSSMHIDNNILLITN-ASKFHLPVRVYT 535
++++ N+ L TN + F +P+++Y+
Sbjct: 460 AVKDIAINLFTNVFLTTNIGAIFAIPLQIYS 490
Score = 33.1 bits (74), Expect = 2.6
Identities = 89/400 (22%), Positives = 134/400 (33%), Gaps = 56/400 (14%)
Query: 1419 DDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPT 1478
++++ T SNP +E +KE + + K ++ K++ L K++P
Sbjct: 1057 EENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPE 1116
Query: 1479 DVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALA 1538
+ P + + P L R+N + +P +N K VD +P +
Sbjct: 1117 NHLPRNSPQYHQPDLPEISRKNNGNNQQVPV--------KNEVDHCENLKKVDTKPSSEK 1168
Query: 1539 KFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLN---ADIFLKQ 1595
K S+E EK P P K + +LQ LN + K
Sbjct: 1169 KIHKTSRE-----DMFSEKQDIPFVEQEDPYRK--KKLQEKREGNLQNLNWSKSRTCRKN 1221
Query: 1596 RQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQ--PNGSKHKLTKAASLPGK 1653
++ P S P + V S S SSD ++ S ++ K A
Sbjct: 1222 KKRGVAPVSRPPEQSDLKLVC----SDFERSELSSDINVRSWCIQESTREVCK-ADAEIA 1276
Query: 1654 NGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNP 1713
+ P GY + P K S+ SS G S V + S G W S+
Sbjct: 1277 SSLPAAQREAEGYYQKPEKKCVDKFCSDS---SSDCGSSSGSVRA----SRGSWGSWSST 1329
Query: 1714 SSPD-----FTPLNSFSAFGNSF---NLTGEVFSKLGLSRS-CNQASQRSWNEFNSGPSY 1764
SS D F G+S + E L LS + CN + NS P Y
Sbjct: 1330 SSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMT------VNSLPQY 1383
Query: 1765 LWESPATDPSPSWPASSGSPTHTATSV-LGNTSGLWSTTP 1803
PS P+ PT L + LW T P
Sbjct: 1384 --------AEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPP 1415
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 67.8 bits (164), Expect = 1e-10
Identities = 102/436 (23%), Positives = 163/436 (37%), Gaps = 54/436 (12%)
Query: 1236 RAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAK-QSQHGSQHHA 1294
+AK+S S S +S K +P+ + + T A K A ++ S +
Sbjct: 163 KAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSS 222
Query: 1295 HSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAM 1354
S + P+ P+ + ++ AP+ + P R SS SSEDS + E
Sbjct: 223 SSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSS---SSEDSS-SDEEEEQ 278
Query: 1355 DKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELK 1414
K + P V PPS P K G +PPKK EK++ P E
Sbjct: 279 KKPMKNKPGPYSSV---PPPSAPPPKKSLG------TQPPKKAVEKQQ-----PVESSED 324
Query: 1415 DSLADDDSSSTTTETSNPDTEPLLKEDTEK----QKGKQAMPEKHESEMSQVKQKSKKLL 1470
S D+S S++ E P T+ ++ + T K +K ++ + +S+ S+ + K
Sbjct: 325 SS---DESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPA 381
Query: 1471 NIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSK--SRNAQKTKGTSK 1528
K ++ P KQ K+ A +S S+ S ++++ K
Sbjct: 382 GTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKM 441
Query: 1529 LVDNRPPALAKF---LPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQ 1585
+ +P A AK LP Q + S + DS SS + K S
Sbjct: 442 VATTKPKATAKAALSLPAKQAPQGSRDSSSDSDS-------------SSSEEEEEKTSKS 488
Query: 1586 TLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLT 1645
+ K+ Q A+PS PA+ A+ + NSSSS D ++ K K +
Sbjct: 489 AVK-----KKPQKVAGGAAPSKPAS-----AKKGKAESSNSSSSDDSSEEEEEKLKGKGS 538
Query: 1646 KAASLPGKNGNPTFAA 1661
P NG A
Sbjct: 539 PRPQAPKANGTSALTA 554
Score = 58.5 bits (140), Expect = 6e-08
Identities = 76/367 (20%), Positives = 129/367 (35%), Gaps = 51/367 (13%)
Query: 1227 RNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPL-------VLDSNTVTQGHTAGRK 1279
R + + N +A +SSS+SS +S+ S + +P V+ V T RK
Sbjct: 204 RAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRK 263
Query: 1280 SKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSAR 1339
S ++ S + P++ P P P P P+ + P + S+
Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSE 323
Query: 1340 HSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEE 1399
SS++SD +S E ++PP+ SK KP P KK E
Sbjct: 324 DSSDESDSSSEEE------------------KKPPTKAVVSKATTKP-----PPAKKAAE 360
Query: 1400 KEKKGKGKPQEDELKDSLADDDSSSTTTETSN--------PDTEPLLKEDTEKQKGKQAM 1451
D +D A + TT +SN P +P G++ +
Sbjct: 361 SSSDSS---DSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 1452 PEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAM 1511
K +S S+ + S + KK + T ++ + + P + + + S +
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDS------SS 471
Query: 1512 TSGSKSRNAQKTKGTSKLVDNRPPAL----AKFLPNSQELGNTSSSEGEKDSPPPEWDSV 1567
S S S ++ K + V +P + A P S + G SS E +
Sbjct: 472 DSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEE 531
Query: 1568 PVHKPGS 1574
+ GS
Sbjct: 532 KLKGKGS 538
Score = 51.6 bits (122), Expect = 7e-06
Identities = 61/285 (21%), Positives = 108/285 (37%), Gaps = 22/285 (7%)
Query: 1222 SSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSK 1281
++ S+ +S+D ++ + S + T+ +++ + SP V + Q G+K
Sbjct: 358 AAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 1282 GAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHS 1341
K S+ + S E+ + + +P+ + A L+ P+ + +R S
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATT-------KPKATAKAALSLPAK-QAPQGSRDS 469
Query: 1342 SEDSDITSLIEAMDKDFDH--HDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEE 1399
S DSD +S E +K P P P KGK + +EE
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEE 529
Query: 1400 KEK-KGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESE 1458
+EK KGKG P+ K ++ T+ T+ E+ E++K K A+
Sbjct: 530 EEKLKGKGSPRPQAPK-------ANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGS 582
Query: 1459 MSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPS 1503
+ + KQ K+ K L+ P T P K + S
Sbjct: 583 LKKRKQNEA----AKEAETPQAKKIKLQTPNTFPKRKKGEKRASS 623
Score = 44.3 bits (103), Expect = 0.001
Identities = 98/468 (20%), Positives = 158/468 (33%), Gaps = 107/468 (22%)
Query: 1249 AQAASSQSANKTSPLVLDSNTVTQGHTAGRK-------SKGAKQSQHGSQHHAHSPLEQH 1301
A A+ Q AN +S L + S + RK +K AK+ S S E+
Sbjct: 37 ATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEE 96
Query: 1302 PQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHH 1361
Q P P + P +R+ P + +SS+ SS+D D
Sbjct: 97 VQGP---PAKKAAVPA-KRVGLPPGKAAAKASESSSSEESSDDDD--------------- 137
Query: 1362 DSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEK------------------- 1402
E+ P KG + PPKK + +
Sbjct: 138 ---------EEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKIT 188
Query: 1403 ------KGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKH- 1455
+ K P+ +A+ ++S+++ +S+ + +E+ K+ +P+K
Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV 248
Query: 1456 -------------------ESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPY----TPP 1492
E S +++ KK + K + V P S P T P
Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQP 308
Query: 1493 LESKQRRNLPSKIPLPTAMTSGSKSRNAQK--TKGTSKLVDNRPPALAKFLPNSQELGNT 1550
+ + P + ++ S S S +K TK +PP K +S + ++
Sbjct: 309 PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDS 368
Query: 1551 SSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAA 1610
SSE D P G++ +S K ++ T K P A P
Sbjct: 369 DSSED---------DEAPSKPAGTTKNSSNKPAVTT-------KSPAVKPAAAPKQPVGG 412
Query: 1611 PCPFVAR--GSYSSIVNSSSSSDPKIKQPNG-SKHKLT--KAASLPGK 1653
+ R S SS SSSS + K K+ +K K T A SLP K
Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK 460
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 67.8 bits (164), Expect = 1e-10
Identities = 88/364 (24%), Positives = 153/364 (42%), Gaps = 41/364 (11%)
Query: 1236 RAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAH 1295
+AK+ +++ +A S A SP S + + K+K + + S A
Sbjct: 651 KAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSP-EKAKSPVKEEAKSPEKAK 709
Query: 1296 SPLEQHPQPPLPPPVPQPQEPQ-PERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAM 1354
SP+++ + P P +E + PE+ PE+A S ++ D+ S EA
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE-KAKTLDVKSP-EAK 767
Query: 1355 DKDFDHHDSPALEVFTEQPPSPLP---KSKGKGK-PLQRKVKPPKKQEEKEKKGKG---- 1406
+ SPA + F E+ SP+ KS K K PL+ K P+K+ K+++ K
Sbjct: 768 TPAKEEARSPA-DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE 826
Query: 1407 --KPQEDELKD--SLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQV 1462
KPQE ++K+ A+++ + T +T + +E +K+ K + EK E + +
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKK-DSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 1463 KQKS----KKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGS--- 1515
K+ K+ KK++PT K + ++ + K++ + K P S
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945
Query: 1516 -KSRNAQKTKGT----SKLVDNRPPALAKFLPNSQ-----------ELGNTSSSEGEKDS 1559
K A + K T +K + +P AK + + E SSS +KDS
Sbjct: 946 EKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDS 1005
Query: 1560 PPPE 1563
PPE
Sbjct: 1006 KPPE 1009
Score = 52.0 bits (123), Expect = 5e-06
Identities = 82/413 (19%), Positives = 145/413 (35%), Gaps = 73/413 (17%)
Query: 1236 RAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAH 1295
+AK+ +++ A+A S SP + S K+K + + S A
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP---------EKAKSPTKEEAKSPEKAK 653
Query: 1296 SPLEQHPQPPLPPPVPQPQEPQ-PERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAM 1354
SP ++ + P P E + PE+ A PE+A S S
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS--------- 704
Query: 1355 DKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELK 1414
E+ SP+ K + K ++ P K++ + +K K +E+
Sbjct: 705 ---------------PEKAKSPV---KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Query: 1415 DSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKK 1474
A + T + +P+ + KE+ K PEK + S VK++ K K
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK--FPEKAK---SPVKEEVKSPEKAKS 801
Query: 1475 EIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRP 1534
+ D K E+P ++S + K + + + K + +
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEE--------------EKPQEVKVKEPPKKAEEEKA 847
Query: 1535 PALAKFLPNSQELGNTSSSEG-EKDSPPP---EWDSVPVHKPGSSTDSLYKLSLQTLNAD 1590
PA P ++E ++ E +K++P P E V KP S K+ + A+
Sbjct: 848 PA----TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES-----KVEAKKEEAE 898
Query: 1591 IFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHK 1643
++ PTP +P A+ + V D K K+P+ K
Sbjct: 899 ----DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Score = 50.4 bits (119), Expect = 2e-05
Identities = 58/277 (20%), Positives = 108/277 (38%), Gaps = 41/277 (14%)
Query: 1212 KQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVT 1271
K+ S S + DV++ AK + +R+ A ++ SP+ + +
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK---SPVKEEVKSPE 797
Query: 1272 QGHTAGRKSKGAKQSQHGSQHHAHSPL--EQHPQ------PPLP------PPVPQPQEPQ 1317
+ + ++ A + + + SP+ E+ PQ PP P P+ +E +
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857
Query: 1318 PERLSPAPLAHPSHPE------------RASSARHSSEDSDITSLIEAMDKDF------- 1358
+ AP P+ + S E+++ + +K+
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK 917
Query: 1359 -DHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSL 1417
D EV ++P K+K KP ++K P+K++ KE+K K KP+E ++
Sbjct: 918 EDAKPKEKTEVAKKEPDDA--KAKEPSKPAEKKEAAPEKKDTKEEKAK-KPEEKPKTEAK 974
Query: 1418 ADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEK 1454
A +D + + E S P E K + QK + PEK
Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKP-PEK 1010
Score = 46.6 bits (109), Expect = 2e-04
Identities = 78/402 (19%), Positives = 136/402 (33%), Gaps = 40/402 (9%)
Query: 1270 VTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPV-PQPQEPQP---ERLSPAP 1325
VT+ K + K+ + G + A E+ PP P+ + P E SPA
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 1326 LAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGK 1385
P E S A S + SPA E P + P+ +
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKA---------------KSPAKEEAKSPPEAKSPEKEEAKS 574
Query: 1386 PLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADD--DSSSTTTETSNPDTEPLLKEDTE 1443
P + VK P+K + K+ P E + + + + + E +P E
Sbjct: 575 PAE--VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEV 632
Query: 1444 KQKGKQAMPEKHESE-----MSQVKQKSKKLLNIKKEIPTDVK-PSSLELPYTPPLESKQ 1497
K K P K E++ S K+++K K + + K P + P +S +
Sbjct: 633 KSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPE 692
Query: 1498 RRNLP----SKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSS 1553
+ P +K P ++++ +K K K + + P AK + +
Sbjct: 693 KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK-EEAKTPEKAKSPVKEEAKSPEKAK 751
Query: 1554 EGEK----DSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPA 1609
EK D PE + + S D + + + ++ ++ SP P
Sbjct: 752 SPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPE 811
Query: 1610 APCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLP 1651
P S + + K+K+P K + KA + P
Sbjct: 812 KEIP-KKEEVKSPVKEEEKPQEVKVKEP-PKKAEEEKAPATP 851
Score = 39.7 bits (91), Expect = 0.028
Identities = 60/313 (19%), Positives = 121/313 (38%), Gaps = 24/313 (7%)
Query: 1363 SPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLA--DD 1420
S ++V +E+ + KS+ + ++ + + + EE ++ + + +E+E K+ ++
Sbjct: 433 STHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEE 492
Query: 1421 DSSSTTTETSNPDTEPLLKEDTE---------KQKGKQAMPEKHESEM-SQVKQKSKKLL 1470
++ ET +P E + E K + PEK E++ ++VK K
Sbjct: 493 EAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS 552
Query: 1471 NIKKEI---PTDVKPSSLELPYTPPLESKQRRNLPSK--IPLPTAMTSGSKSRNAQKTKG 1525
K+E P P E ++S ++ P+K P S K+++ K +
Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 1526 TSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQ 1585
S P P + + S ++++ PE P + S + +
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK----AKS 668
Query: 1586 TLNADIFLKQRQTSPTPA-SPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKL 1644
+ A+ ++ SP A + SP A P + S + S + K P +K +
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSP--VKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726
Query: 1645 TKAASLPGKNGNP 1657
+ A P K +P
Sbjct: 727 KEEAKTPEKAKSP 739
Score = 37.4 bits (85), Expect = 0.14
Identities = 62/289 (21%), Positives = 109/289 (37%), Gaps = 23/289 (7%)
Query: 1376 PLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTE 1435
P+P S +G P V K + +EK K E K+++ ++ + T T TE
Sbjct: 417 PIPFSLPEGLPKIPSVSTHIKVKSEEKI---KVVEKSEKETVIVEEQTEETQVTEEV-TE 472
Query: 1436 PLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLES 1495
KE E++ ++ E+ E+E + + KS P + +S E P++
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKS----------PPAEEAASPEKEAKSPVKE 522
Query: 1496 KQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTS--SS 1553
+ + +K P S ++ ++ +K K +K PP P +E + + S
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS--PEKEEAKSPAEVKS 580
Query: 1554 EGEKDSPPPEWDSVPVH--KPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAP 1611
+ SP E P P + + + + A +K+ SP SP A
Sbjct: 581 PEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK-SPEKAK 639
Query: 1612 CPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFA 1660
P + S + S + K P +K + A P K +P A
Sbjct: 640 SP--TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686
Score = 35.0 bits (79), Expect = 0.69
Identities = 66/288 (22%), Positives = 106/288 (36%), Gaps = 40/288 (13%)
Query: 1388 QRKVKPPKKQEEKEKKGKGKPQ----EDELKDSLADDDSS-------------STTTETS 1430
+ + K K++E KE++G + + E+E K A++ +S + E
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK 531
Query: 1431 NPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVK-PSSLELPY 1489
+P+ E K K P K E++ S + KS + K P +VK P + P
Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAK-SPPEAKSPEKEEAKS--PAEVKSPEKAKSPA 588
Query: 1490 TPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKL-VDNRPPALAKFLPNSQELG 1548
+S P K P + S + K +K + + P AK P +E
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK-SPTKEEAK 647
Query: 1549 N--TSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPA-SP 1605
+ + S ++++ PE PV S + A +K SP A SP
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE----------KAKSPVKAEAKSPEKAKSP 697
Query: 1606 SPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGK 1653
A P A+ S V + S K K P + K + A P K
Sbjct: 698 VKEEAKSPEKAK----SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Score = 31.2 bits (69), Expect = 10.0
Identities = 24/117 (20%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 1310 VPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVF 1369
VP P++ P ++ A P E+ A+ +D+ + +K + +
Sbjct: 903 VPTPEKEAPAKVEVKEDAKPK--EKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 1370 TEQPPSPLPKSKGKGKPLQRKV--KPPKKQEEKEKKGKGKPQEDELKDSLADDDSSS 1424
+ P PK++ K K + + +P K + EK +K Q+D A +D ++
Sbjct: 961 KAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 64.3 bits (155), Expect = 1e-09
Identities = 166/748 (22%), Positives = 257/748 (34%), Gaps = 147/748 (19%)
Query: 1152 RRLSFEASNPPFDVGRPFDLRRIV--GISSEGNLNTLSCD---PGHSRGFCGAGGSSSRP 1206
R+ ++S+PP GRP D R G+S +T + PG S P
Sbjct: 83 RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRS------------P 130
Query: 1207 SAGSHKQCGPSVHPHSSHSNRNSADV-ENVRAKNSSSTSSRTSAQAASSQSANKTSPLVL 1265
S S K+ +++ D+ E ++ S +A +A S NK +P L
Sbjct: 131 STISLKE------------SKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 1266 DSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLP-------PPVPQPQEP-- 1316
S++ +K K ++ Q + PL+Q P P+P P+ Q P
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 1317 ----QPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQ 1372
QPE++ P P + ++ + +D + ++ +
Sbjct: 239 ISSQQPEKIKSQP------PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
Query: 1373 PPSPLPKSKGKGKPLQRKV--KPPKKQ--EEKEKKGKGKP--QEDELKDSLADDDSS--- 1423
P S K P+Q+ KPP +Q EK + G KP Q L LA +
Sbjct: 293 SVKPSLPSPSK-PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 1424 -STTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKK--LLNIKKEIPTDV 1480
T+ P +PL K +Q EK SE K ++ + + P
Sbjct: 352 PVQPPGTTKPPAQPL---GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 1481 KPSSLELPYTPPLESKQRRNLPSKIPLPT-------------AMTSGSKSRNAQKTKGTS 1527
KP + ++ PL + P+K P PT A +G +AQ+T T
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468
Query: 1528 KLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTL 1587
++ P AK P Q+ G + S P P +PGS+
Sbjct: 469 P--PSQLPGPAK--PPPQQPGPAKPPPQQPGSAKP-----PSQQPGST------------ 507
Query: 1588 NADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSK---HKL 1644
K P PA PSP GS S+ P +QP+ +K +
Sbjct: 508 ------KPPPQQPGPAKPSPQQP-------GSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Query: 1645 TKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSS 1704
TK S G +G P + K P G K + L H P ++
Sbjct: 555 TKPVSQTG-SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL--LHVPEKAN----- 606
Query: 1705 GLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSY 1764
N + T + S F + +LT EV L L+ +A
Sbjct: 607 ------FNTCTECQTTVCSLCGFNPNPHLT-EVKEWLCLNCQMKRA-------------- 645
Query: 1765 LWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPAN 1824
L A PS P +P T ++V ++ T+P + +LS A P
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
Query: 1825 TLASIGLMGTENSPA---PHAPSTSSPA 1849
+ L G+ ++ A P A S S PA
Sbjct: 706 LVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Score = 43.9 bits (102), Expect = 0.001
Identities = 91/430 (21%), Positives = 148/430 (34%), Gaps = 59/430 (13%)
Query: 1220 PHSSHSNRNSADVENVRAKNSSSTSSRTSA---QAASSQSANKTSPLVLDSNTVTQGHTA 1276
P S +A V A + SS + ++ AA Q +K V Q
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 1277 GRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQP---ERLSPAPLAHPSHPE 1333
G S AKQ P PP P VP Q+ P ++ + P+
Sbjct: 714 GSPSAKAKQPPEADSL-------SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDL 766
Query: 1334 RASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKP 1393
+SS+ ++ DI S + + +P L+ + +P P + K P K P
Sbjct: 767 VSSSS--ATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1394 PKKQEEK-------EKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDT---- 1442
+ K + KG+ Q D ++ ++ + T + PD +P+ K
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKK--EEPKKAQTKMSPKPDAKPMPKGSPTPPG 880
Query: 1443 EKQKGKQAMPEKHESEMSQVKQKSKKL-LNIKKEIPTDVKPSSLELPYTPPLES------ 1495
+ Q +P +S Q + + L L + P +P++ + T L
Sbjct: 881 PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS-QPTTPQETVTGKLFGFGASIF 939
Query: 1496 KQRRNLPSKIPLP---------TAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQE 1546
Q NL S P M ++G K PPA AK +P +E
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
Query: 1547 LGNTSSS--EGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPAS 1604
++ E + + P + KP DS ++L A+ Q+ PT
Sbjct: 1000 TKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS------KSLTAE---PQKAVLPTKLE 1050
Query: 1605 PSP-PAAPCP 1613
SP P + CP
Sbjct: 1051 KSPKPESTCP 1060
Score = 43.9 bits (102), Expect = 0.001
Identities = 47/187 (25%), Positives = 68/187 (36%), Gaps = 23/187 (12%)
Query: 1231 DVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGS 1290
D + + A+ + S+ S T S L + T G T G++ K A Q GS
Sbjct: 2322 DKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQE-KPASQLPSGS 2380
Query: 1291 QHHAHSPLEQHP-----------QPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSAR 1339
+ P + P QPP PPP P P P P P PL P+ P+ +
Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440
Query: 1340 H----SSEDSDITSLIEAM-----DKDFDHHDSPALEVFTEQPP--SPLPKSKGKGKPLQ 1388
+S + T L +A+ + P + T PP P P S G
Sbjct: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT 2500
Query: 1389 RKVKPPK 1395
+ +P K
Sbjct: 2501 HRPEPSK 2507
Score = 41.2 bits (95), Expect = 0.010
Identities = 98/480 (20%), Positives = 163/480 (33%), Gaps = 67/480 (13%)
Query: 1290 SQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITS 1349
SQ +P++Q P P PP P P+ AP P A S E T
Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQGP----PKSTGQAP------PAPAKSIPVKKE----TK 1001
Query: 1350 LIEAMDKDFDHHDSPALE-VFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKP 1408
A + +P ++ TE+ P P+ SK Q+ V P K ++ + +
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Query: 1409 QEDELKDSLADDDSSSTTTETSNP-------DTEPLLKEDTE------------------ 1443
+ EL D + +T TE N + P L E E
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 1444 ------KQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQ 1497
G +A P +E S K + + K+ +VK + ++ E+
Sbjct: 1122 IRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS 1181
Query: 1498 RRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRP-PALAKFLPNSQELGNTSSSE-- 1554
+P P T + + + S L + +P P K +P +++ +
Sbjct: 1182 MEKIP-----PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL 1236
Query: 1555 GEKDSPPPEWDSVPVHKPGSSTDSLYK-LSLQTLNADIFLKQRQTSPTPASPSPPAAPCP 1613
EK P + +P K + + + L Q A+ L+ R T P
Sbjct: 1237 EEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME 1296
Query: 1614 FVARGSYSSIVNSSSSSDPKIKQ----PNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKS 1669
+ G+ S+ + IK+ P +K + + + ++ KS
Sbjct: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
Query: 1670 PGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSD-----SSGLWSPVSNPSSP-DFTPLNS 1723
P G + + G SSSLG + + +D D +S S+PSSP D L S
Sbjct: 1357 P--QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414
Score = 38.5 bits (88), Expect = 0.063
Identities = 76/341 (22%), Positives = 116/341 (34%), Gaps = 70/341 (20%)
Query: 1311 PQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFT 1370
P P PQP +L AP+ S ++S + SP +
Sbjct: 652 PVPSSPQP-KLKTAPVTTTSAVSKSSPQPQQT--------------------SPKKDAAP 690
Query: 1371 EQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETS 1430
+Q S P+ K K PL VK P K K P+ D L
Sbjct: 691 KQDLSKAPEPK-KPPPL---VKQPTLHGSPSAKAKQPPEADSLSKPA------------- 733
Query: 1431 NPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYT 1490
P EP + + +K P++ + S K +IP+ S E T
Sbjct: 734 -PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 1491 PPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNT 1550
PPL++ + PS+ PT +K RP + +K + + G +
Sbjct: 793 PPLKTDSAK--PSQSFPPT----------GEKVSPFDSKAIPRPASDSKIISHP---GPS 837
Query: 1551 SSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTP------AS 1604
S S+G+K PV K + K+S + +A K T P P
Sbjct: 838 SESKGQKQVD-------PVQKKEEPKKAQTKMSPKP-DAKPMPKGSPTPPGPRPTAGQTV 889
Query: 1605 PSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLT 1645
P+P +P P +S +N S +D QP + +T
Sbjct: 890 PTPQQSPKPQEQSRRFS--LNLGSITDAPKSQPTTPQETVT 928
Score = 37.7 bits (86), Expect = 0.11
Identities = 41/150 (27%), Positives = 60/150 (40%), Gaps = 15/150 (10%)
Query: 1516 KSRNAQKTKGT-SKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPG- 1573
K A++TK + S+ V + PP+ LP ++L T + GE +P P
Sbjct: 2324 KELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSV 2383
Query: 1574 SSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPK 1633
SS + + ++ + DI + P P P PP P P + +S P
Sbjct: 2384 SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP-------PPPLPPPTSPKPT 2436
Query: 1634 IKQPNGSKHKLTKAASLPGKNGNPTFAAVT 1663
I K KLT A+ P P F AVT
Sbjct: 2437 IL----PKKKLTVAS--PVTTATPLFDAVT 2460
Score = 36.6 bits (83), Expect = 0.24
Identities = 82/429 (19%), Positives = 146/429 (34%), Gaps = 53/429 (12%)
Query: 1200 GGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANK 1259
G P A S + P P S S + + + V+ +T A+ + +
Sbjct: 1120 GDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQ-VKLVKKQEQEVKTEAEKVILEKVKE 1178
Query: 1260 TSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPE 1319
T + VT +SK K Q P E+ P + ++P E
Sbjct: 1179 TLSMEKIPPMVTTDQKQ-EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLE 1237
Query: 1320 RLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQP------ 1373
P P PE +SA + + S ++ ++ + +P +QP
Sbjct: 1238 EKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEG 1297
Query: 1374 -----PSPLPKSKGKG-KPLQRKVKPP-------------KKQEEKEKKGKGKPQEDELK 1414
P LPK K K ++ + +PP K ++E +K Q+ +
Sbjct: 1298 LPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 1415 DSLAD-----DDSSSTTTE------TSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVK 1463
L+D D SS+ E T D LK+D+ Q+ + P S++++++
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSP----SDLAKLE 1413
Query: 1464 QKSKKLLNIKKEIPTDVKPSSLELPY--TPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQ 1521
+L + D K P+ +P Q + L ++ + +
Sbjct: 1414 STVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQE 1473
Query: 1522 KTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGE-----KDSPPPEWDSVPVHK----P 1572
+ K T K + +K E + ++ E ++S E VP K
Sbjct: 1474 ERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSV 1533
Query: 1573 GSSTDSLYK 1581
GSS+ YK
Sbjct: 1534 GSSSSDEYK 1542
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 64.3 bits (155), Expect = 1e-09
Identities = 166/748 (22%), Positives = 257/748 (34%), Gaps = 147/748 (19%)
Query: 1152 RRLSFEASNPPFDVGRPFDLRRIV--GISSEGNLNTLSCD---PGHSRGFCGAGGSSSRP 1206
R+ ++S+PP GRP D R G+S +T + PG S P
Sbjct: 83 RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRS------------P 130
Query: 1207 SAGSHKQCGPSVHPHSSHSNRNSADV-ENVRAKNSSSTSSRTSAQAASSQSANKTSPLVL 1265
S S K+ +++ D+ E ++ S +A +A S NK +P L
Sbjct: 131 STISLKE------------SKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 1266 DSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLP-------PPVPQPQEP-- 1316
S++ +K K ++ Q + PL+Q P P+P P+ Q P
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 1317 ----QPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQ 1372
QPE++ P P + ++ + +D + ++ +
Sbjct: 239 ISSQQPEKIKSQP------PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGE 292
Query: 1373 PPSPLPKSKGKGKPLQRKV--KPPKKQ--EEKEKKGKGKP--QEDELKDSLADDDSS--- 1423
P S K P+Q+ KPP +Q EK + G KP Q L LA +
Sbjct: 293 SVKPSLPSPSK-PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 1424 -STTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKK--LLNIKKEIPTDV 1480
T+ P +PL K +Q EK SE K ++ + + P
Sbjct: 352 PVQPPGTTKPPAQPL---GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 1481 KPSSLELPYTPPLESKQRRNLPSKIPLPT-------------AMTSGSKSRNAQKTKGTS 1527
KP + ++ PL + P+K P PT A +G +AQ+T T
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468
Query: 1528 KLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTL 1587
++ P AK P Q+ G + S P P +PGS+
Sbjct: 469 P--PSQLPGPAK--PPPQQPGPAKPPPQQPGSAKP-----PSQQPGST------------ 507
Query: 1588 NADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSK---HKL 1644
K P PA PSP GS S+ P +QP+ +K +
Sbjct: 508 ------KPPPQQPGPAKPSPQQP-------GSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Query: 1645 TKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSS 1704
TK S G +G P + K P G K + L H P ++
Sbjct: 555 TKPVSQTG-SGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL--LHVPEKAN----- 606
Query: 1705 GLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSY 1764
N + T + S F + +LT EV L L+ +A
Sbjct: 607 ------FNTCTECQTTVCSLCGFNPNPHLT-EVKEWLCLNCQMKRA-------------- 645
Query: 1765 LWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPAN 1824
L A PS P +P T ++V ++ T+P + +LS A P
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPP 705
Query: 1825 TLASIGLMGTENSPA---PHAPSTSSPA 1849
+ L G+ ++ A P A S S PA
Sbjct: 706 LVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Score = 43.9 bits (102), Expect = 0.001
Identities = 91/430 (21%), Positives = 148/430 (34%), Gaps = 59/430 (13%)
Query: 1220 PHSSHSNRNSADVENVRAKNSSSTSSRTSA---QAASSQSANKTSPLVLDSNTVTQGHTA 1276
P S +A V A + SS + ++ AA Q +K V Q
Sbjct: 654 PSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 1277 GRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQP---ERLSPAPLAHPSHPE 1333
G S AKQ P PP P VP Q+ P ++ + P+
Sbjct: 714 GSPSAKAKQPPEADSL-------SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDL 766
Query: 1334 RASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKP 1393
+SS+ ++ DI S + + +P L+ + +P P + K P K P
Sbjct: 767 VSSSS--ATTKPDIPS--SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1394 PKKQEEK-------EKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDT---- 1442
+ K + KG+ Q D ++ ++ + T + PD +P+ K
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKK--EEPKKAQTKMSPKPDAKPMPKGSPTPPG 880
Query: 1443 EKQKGKQAMPEKHESEMSQVKQKSKKL-LNIKKEIPTDVKPSSLELPYTPPLES------ 1495
+ Q +P +S Q + + L L + P +P++ + T L
Sbjct: 881 PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKS-QPTTPQETVTGKLFGFGASIF 939
Query: 1496 KQRRNLPSKIPLP---------TAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQE 1546
Q NL S P M ++G K PPA AK +P +E
Sbjct: 940 SQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKE 999
Query: 1547 LGNTSSS--EGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPAS 1604
++ E + + P + KP DS ++L A+ Q+ PT
Sbjct: 1000 TKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS------KSLTAE---PQKAVLPTKLE 1050
Query: 1605 PSP-PAAPCP 1613
SP P + CP
Sbjct: 1051 KSPKPESTCP 1060
Score = 43.9 bits (102), Expect = 0.001
Identities = 47/187 (25%), Positives = 68/187 (36%), Gaps = 23/187 (12%)
Query: 1231 DVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGS 1290
D + + A+ + S+ S T S L + T G T G++ K A Q GS
Sbjct: 2322 DKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQE-KPASQLPSGS 2380
Query: 1291 QHHAHSPLEQHP-----------QPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSAR 1339
+ P + P QPP PPP P P P P P PL P+ P+ +
Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPK 2440
Query: 1340 H----SSEDSDITSLIEAM-----DKDFDHHDSPALEVFTEQPP--SPLPKSKGKGKPLQ 1388
+S + T L +A+ + P + T PP P P S G
Sbjct: 2441 KKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFT 2500
Query: 1389 RKVKPPK 1395
+ +P K
Sbjct: 2501 HRPEPSK 2507
Score = 41.2 bits (95), Expect = 0.010
Identities = 98/480 (20%), Positives = 163/480 (33%), Gaps = 67/480 (13%)
Query: 1290 SQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITS 1349
SQ +P++Q P P PP P P+ AP P A S E T
Sbjct: 956 SQSGPGAPMKQAPAPSQPPTSQGP----PKSTGQAP------PAPAKSIPVKKE----TK 1001
Query: 1350 LIEAMDKDFDHHDSPALE-VFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKP 1408
A + +P ++ TE+ P P+ SK Q+ V P K ++ + +
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Query: 1409 QEDELKDSLADDDSSSTTTETSNP-------DTEPLLKEDTE------------------ 1443
+ EL D + +T TE N + P L E E
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 1444 ------KQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQ 1497
G +A P +E S K + + K+ +VK + ++ E+
Sbjct: 1122 IRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS 1181
Query: 1498 RRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRP-PALAKFLPNSQELGNTSSSE-- 1554
+P P T + + + S L + +P P K +P +++ +
Sbjct: 1182 MEKIP-----PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL 1236
Query: 1555 GEKDSPPPEWDSVPVHKPGSSTDSLYK-LSLQTLNADIFLKQRQTSPTPASPSPPAAPCP 1613
EK P + +P K + + + L Q A+ L+ R T P
Sbjct: 1237 EEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME 1296
Query: 1614 FVARGSYSSIVNSSSSSDPKIKQ----PNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKS 1669
+ G+ S+ + IK+ P +K + + + ++ KS
Sbjct: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
Query: 1670 PGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSD-----SSGLWSPVSNPSSP-DFTPLNS 1723
P G + + G SSSLG + + +D D +S S+PSSP D L S
Sbjct: 1357 P--QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLES 1414
Score = 38.5 bits (88), Expect = 0.063
Identities = 76/341 (22%), Positives = 116/341 (34%), Gaps = 70/341 (20%)
Query: 1311 PQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFT 1370
P P PQP +L AP+ S ++S + SP +
Sbjct: 652 PVPSSPQP-KLKTAPVTTTSAVSKSSPQPQQT--------------------SPKKDAAP 690
Query: 1371 EQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETS 1430
+Q S P+ K K PL VK P K K P+ D L
Sbjct: 691 KQDLSKAPEPK-KPPPL---VKQPTLHGSPSAKAKQPPEADSLSKPA------------- 733
Query: 1431 NPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYT 1490
P EP + + +K P++ + S K +IP+ S E T
Sbjct: 734 -PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 1491 PPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNT 1550
PPL++ + PS+ PT +K RP + +K + + G +
Sbjct: 793 PPLKTDSAK--PSQSFPPT----------GEKVSPFDSKAIPRPASDSKIISHP---GPS 837
Query: 1551 SSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTP------AS 1604
S S+G+K PV K + K+S + +A K T P P
Sbjct: 838 SESKGQKQVD-------PVQKKEEPKKAQTKMSPKP-DAKPMPKGSPTPPGPRPTAGQTV 889
Query: 1605 PSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLT 1645
P+P +P P +S +N S +D QP + +T
Sbjct: 890 PTPQQSPKPQEQSRRFS--LNLGSITDAPKSQPTTPQETVT 928
Score = 37.7 bits (86), Expect = 0.11
Identities = 41/150 (27%), Positives = 60/150 (40%), Gaps = 15/150 (10%)
Query: 1516 KSRNAQKTKGT-SKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPG- 1573
K A++TK + S+ V + PP+ LP ++L T + GE +P P
Sbjct: 2324 KELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSV 2383
Query: 1574 SSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPK 1633
SS + + ++ + DI + P P P PP P P + +S P
Sbjct: 2384 SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP-------PPPLPPPTSPKPT 2436
Query: 1634 IKQPNGSKHKLTKAASLPGKNGNPTFAAVT 1663
I K KLT A+ P P F AVT
Sbjct: 2437 IL----PKKKLTVAS--PVTTATPLFDAVT 2460
Score = 36.6 bits (83), Expect = 0.24
Identities = 82/429 (19%), Positives = 146/429 (34%), Gaps = 53/429 (12%)
Query: 1200 GGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANK 1259
G P A S + P P S S + + + V+ +T A+ + +
Sbjct: 1120 GDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQ-VKLVKKQEQEVKTEAEKVILEKVKE 1178
Query: 1260 TSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPE 1319
T + VT +SK K Q P E+ P + ++P E
Sbjct: 1179 TLSMEKIPPMVTTDQKQ-EESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLE 1237
Query: 1320 RLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQP------ 1373
P P PE +SA + + S ++ ++ + +P +QP
Sbjct: 1238 EKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEG 1297
Query: 1374 -----PSPLPKSKGKG-KPLQRKVKPP-------------KKQEEKEKKGKGKPQEDELK 1414
P LPK K K ++ + +PP K ++E +K Q+ +
Sbjct: 1298 LPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSP 1357
Query: 1415 DSLAD-----DDSSSTTTE------TSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVK 1463
L+D D SS+ E T D LK+D+ Q+ + P S++++++
Sbjct: 1358 QGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSP----SDLAKLE 1413
Query: 1464 QKSKKLLNIKKEIPTDVKPSSLELPY--TPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQ 1521
+L + D K P+ +P Q + L ++ + +
Sbjct: 1414 STVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQE 1473
Query: 1522 KTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGE-----KDSPPPEWDSVPVHK----P 1572
+ K T K + +K E + ++ E ++S E VP K
Sbjct: 1474 ERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSV 1533
Query: 1573 GSSTDSLYK 1581
GSS+ YK
Sbjct: 1534 GSSSSDEYK 1542
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 60.5 bits (145), Expect = 2e-08
Identities = 123/574 (21%), Positives = 197/574 (34%), Gaps = 98/574 (17%)
Query: 1220 PHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANK----TSPLVLDSNTVT---- 1271
P S+ NS +N++ K + S A+SS A+ +P L+S T+
Sbjct: 19 PRSAQPPGNS---QNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLESPTLAASSY 75
Query: 1272 QGHTAGRKSKGAKQSQHGSQHHAH------SPLEQHPQPPLPPP---------------- 1309
G G+ S + A +P++ P PP PPP
Sbjct: 76 HGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEVSTQPPPEE 135
Query: 1310 -------VPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHD 1362
VP P P+ + + +P PSH S + ED I S + DFD+ +
Sbjct: 136 PGCGSETVPVPDGPRSDSVEGSPFRPPSH----SFSAVFDEDKPIAS-SGTYNLDFDNIE 190
Query: 1363 SPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKE---------------KKGKGK 1407
++ F P +GK R+ K G
Sbjct: 191 --LVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSLSLQASDFDGASSSGN 248
Query: 1408 PQEDELKD---SLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQ 1464
P+ L S +SST T P L K+ T K K + P K +Q +
Sbjct: 249 PEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTK-KPTETPPVKE----TQQEP 303
Query: 1465 KSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTK 1524
+ L+ + + ++ K S + P ++ P+ P +
Sbjct: 304 DEESLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVPPA 363
Query: 1525 GTSKLVDNRPPALAKFLP--NSQELGNT--SSSEGEKDSP---------------PPEWD 1565
V N PP K LP + E G S S G++DSP WD
Sbjct: 364 SGGGRVQNSPPVGRKTLPLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEFDYSEDKSSWD 423
Query: 1566 SVPVHKPGSSTDSLYKLSLQTLNADIFLK-QRQTSPTPAS-PSPPAAPCPF-VARGSYSS 1622
+ + P + ++ L K + TPAS P PA P +A+G+Y+
Sbjct: 424 NQQENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGTYTF 483
Query: 1623 IVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNK 1682
++ DP P S K+ ++ LP ++ N F T P +K S+
Sbjct: 484 DID--KWDDPNF-NPFSSTSKMQESPKLPQQSYN--FDPDTCDESVDPFKTS-SKTPSSP 537
Query: 1683 TGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSP 1716
+ +S I + ++++G D GL P +P
Sbjct: 538 SKSPASFEIPASAMEANGVDGDGLNKPAKKKKTP 571
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 59.7 bits (143), Expect = 3e-08
Identities = 153/721 (21%), Positives = 257/721 (35%), Gaps = 89/721 (12%)
Query: 1190 PGHSR----GFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSS 1245
PG SR G + + S GPS +SHS+ S D A + ST++
Sbjct: 2573 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDT----ALSPGSTTA 2628
Query: 1246 RTSAQAASS--QSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQ 1303
+ Q +++ S T + +T + G ++ S GS SP
Sbjct: 2629 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIV---EASTRVHSSTGSPRTTLSPASSTSP 2685
Query: 1304 PPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDH--- 1360
P +P+P + + P S+ H S S T+ A H
Sbjct: 2686 GLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 2745
Query: 1361 ----HDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDS 1416
H SP T P S + G+G+ ++ P + P E +
Sbjct: 2746 STIFHSSPDASGTT--PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT 2803
Query: 1417 LADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQK-SKKLLNIKKE 1475
S TTT + T + E++ + + S S S++ +
Sbjct: 2804 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 2863
Query: 1476 IPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPP 1535
P + + T + ++ S+ P T T ++ S P
Sbjct: 2864 SPGSTETTVFPRSTTTSVRGEEPTTFHSR-PASTHTTLFTEDSTTSGLTEESTAFPGSPA 2922
Query: 1536 ALAKFLP---NSQELG-------NTSSSEGEKDSPPPEW------DSVPVHKPGSSTDSL 1579
+ LP + +LG ++S S G SP +S P SST++
Sbjct: 2923 STQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETT 2982
Query: 1580 YKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNG 1639
T + L ++ T+ + SP A P S S +S+S S P G
Sbjct: 2983 TLPGSPTTPS---LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP------G 3033
Query: 1640 SKHKLT--KAASLPGKNGNPTFAAVTAGYDK---SPGGNGFAKVSSNKTGFSSSLGISHA 1694
S H + + G + PT + + G + SPG + + T F SS G +
Sbjct: 3034 STHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTET 3093
Query: 1695 PVDSDGSDSSGL-----------------WSPVSNPSSPDFTPLNSFSAFGNSFNLT--- 1734
+ D + +SGL +P S+ S+ +F ++ +S + T
Sbjct: 3094 TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 3153
Query: 1735 -GEVFSKLGLSRSC-NQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGS---PTHTAT 1789
G + + +S + ++ S F++ + L S + S P ++G+ PT +AT
Sbjct: 3154 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSAT 3213
Query: 1790 SVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTS-SP 1848
SVL G +T+P SS S ++ALP +T T A + T +P +P T+ SP
Sbjct: 3214 SVL---VGEPTTSPISS---GSTETTALPGST---TTAGLSEKSTTFYSSPRSPDTTLSP 3264
Query: 1849 A 1849
A
Sbjct: 3265 A 3265
Score = 57.8 bits (138), Expect = 1e-07
Identities = 163/763 (21%), Positives = 253/763 (33%), Gaps = 92/763 (12%)
Query: 1190 PGHSR----GFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSS 1245
PG SR G + + S GPS +SHS+ S D A + ST++
Sbjct: 2099 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDT----ALSPGSTTA 2154
Query: 1246 RTSAQAASS--QSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQ 1303
+ Q +++ S T + +T + G ++ S GS SP
Sbjct: 2155 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIV---EASTRVHSSTGSPRTTLSPASSTSP 2211
Query: 1304 PPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDH--- 1360
P +P+P + + P S+ H S S T+ A H
Sbjct: 2212 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 2271
Query: 1361 ----HDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDS 1416
H SP T P S + G+G+ ++ P + P E +
Sbjct: 2272 STIFHSSPDASGTT--PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT 2329
Query: 1417 LADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEI 1476
S TTT + T + E++ + + S S V S + +E
Sbjct: 2330 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG------STHSTVSPASTTTPGLSEES 2383
Query: 1477 PT--DVKPSSLE---LPYTPP--LESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKL 1529
T P S E P TP + ++ S+ P T T ++ S
Sbjct: 2384 TTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSR-PASTHTTLFTEDSTTSGLTEESTA 2442
Query: 1530 VDNRPPALAKFLP---NSQELG-------NTSSSEGEKDSPPPEW------DSVPVHKPG 1573
P + LP + +LG ++S S G SP +S P
Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSP 2502
Query: 1574 SSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDP- 1632
SST++ T + L ++ T+ + SP A P S S +S+S S P
Sbjct: 2503 SSTETTTLPGSPTTPS---LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 2559
Query: 1633 ---------KIKQPNGSKHKLTKAASLPGKNGNPTFAA--VTAGYDK------------- 1668
P S+H T +S PG A T+G +
Sbjct: 2560 STHTTAFPDSTTTPGLSRHSTTSHSS-PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2618
Query: 1669 ---SPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFS 1725
SPG T F SS G +H + D + SSG+ + S +P + S
Sbjct: 2619 TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS 2678
Query: 1726 -AFGNSFNLTGE--VFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSG 1782
A S L GE F S + + + SP + P+ +PASS
Sbjct: 2679 PASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST 2738
Query: 1783 SPTHTATSVLGNTS-GLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPH 1841
+ H+ S + ++S TTP S+ +S + + L G+ +P
Sbjct: 2739 TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS 2798
Query: 1842 APST---SSPADDLGQTYNPWRIWSPTIGRRSSDPWSNSHFPH 1881
ST SSP T +P + S +G S+ S H
Sbjct: 2799 EASTTFYSSPRSPT-TTLSPASMTSLGVGEESTTSRSQPGSTH 2840
Score = 57.4 bits (137), Expect = 1e-07
Identities = 155/725 (21%), Positives = 260/725 (35%), Gaps = 97/725 (13%)
Query: 1190 PGHSR----GFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSS 1245
PG SR G + + S GPS +SHS+ S D A + ST++
Sbjct: 1016 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDT----ALSPGSTTA 1071
Query: 1246 RTSAQAASSQSAN--KTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQ 1303
+ Q +++ +N T + +T + G ++ S GS SP
Sbjct: 1072 LSFGQESTTFHSNPGSTHTTLFPDSTTSSGIV---EASTRVHSSTGSPRTTLSPASSTSP 1128
Query: 1304 PPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDH--- 1360
P +P+P + + P S+ H S S T+ A H
Sbjct: 1129 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 1188
Query: 1361 ----HDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDS 1416
H SP T P S + G+G+ ++ P + P E +
Sbjct: 1189 STIFHSSPDASGTT--PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT 1246
Query: 1417 LADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQV-----KQKSKKLLN 1471
S TTT + T + E++ + + S S ++ + +
Sbjct: 1247 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 1306
Query: 1472 IKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVD 1531
+ T V P S T + ++ S+ P T T ++ S
Sbjct: 1307 SRGSTETTVFPHST----TTSVHGEEPTTFHSR-PASTHTTLFTEDSTTSGLTEESTAFP 1361
Query: 1532 NRPPALAKFLP---NSQELG-------NTSSSEGEKDSPPPEW------DSVPVHKPGSS 1575
P + LP + +LG ++S S G K SP +S P SS
Sbjct: 1362 GSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSS 1421
Query: 1576 TDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIK 1635
T++ T + L ++ T+ + SP A P S S +S+S S P
Sbjct: 1422 TETTTLPGSPTTPS---LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP--- 1475
Query: 1636 QPNGSKHKLT--KAASLPGKNGNPTFAAVTAGYDK---SPGGNGFAKVSSNKTGFSSSLG 1690
GS H + + + PT + + G + SPG + + T F SS G
Sbjct: 1476 ---GSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 1532
Query: 1691 ISHAPVDSDGSDSSGL-----------------WSPVSNPSSPDFTPLNSFSAFGNSFNL 1733
+ + D + +SGL +P S+ S+ +F ++ +S +
Sbjct: 1533 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDT 1592
Query: 1734 T----GEVFSKLGLSRSC-NQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGS---PT 1785
T G + + +S + ++ S F++ + L S + S P ++G+ PT
Sbjct: 1593 TPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPT 1652
Query: 1786 HTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPST 1845
+ATSVL G +T+P SS S ++ALP +T T A + T +P +P T
Sbjct: 1653 RSATSVL---VGEPTTSPISS---GSTETTALPGST---TTAGLSEKSTTFYSSPRSPDT 1703
Query: 1846 S-SPA 1849
+ SPA
Sbjct: 1704 TLSPA 1708
Score = 50.4 bits (119), Expect = 2e-05
Identities = 142/705 (20%), Positives = 228/705 (32%), Gaps = 76/705 (10%)
Query: 1192 HSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQA 1251
HSR G + + GS G S +SHS+ S D + S++ SS
Sbjct: 1723 HSR----PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSLGPEST 1776
Query: 1252 ASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVP 1311
S T +L NT G ++ S GS H SP +
Sbjct: 1777 TFHSSPGSTETTLLPDNTTASGLL---EASTPVHSSTGSPHTTLSPAGSTTRQG--ESTT 1831
Query: 1312 QPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDH-------HDSP 1364
P + PAP S S+ H S S T+ A H SP
Sbjct: 1832 FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 1891
Query: 1365 ALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSS 1424
T P + + + + +E + S SS+
Sbjct: 1892 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTS----HSST 1947
Query: 1425 TTTETSNPDT-EPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPS 1483
T T +S P T L++E T + H + S +S++ + S
Sbjct: 1948 THTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE---------STASHS 1998
Query: 1484 SLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPN 1543
S + T L ++ ++ + ++SGS A T+ + + F +
Sbjct: 1999 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT---FHSS 2055
Query: 1544 SQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPA 1603
+ T S S E + +PGS+ + + S T L + T+
Sbjct: 2056 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG----LSRHSTT---- 2107
Query: 1604 SPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVT 1663
S+SS ++ ++ P +G + T + S PG
Sbjct: 2108 ---------------SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL----- 2147
Query: 1664 AGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNS 1723
SPG T F SS G +H + D + SSG+ + S +P +
Sbjct: 2148 -----SPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 2202
Query: 1724 FS-AFGNSFNLTGE--VFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPAS 1780
S A S L GE F S + + + SP + P+ +PAS
Sbjct: 2203 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 2262
Query: 1781 SGSPTHTATSVLGNTS-GLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPA 1839
S + H+ S + ++S TTP S+ +S + + L G+ +P
Sbjct: 2263 STTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG 2322
Query: 1840 PHAPST---SSPADDLGQTYNPWRIWSPTIGRRSSDPWSNSHFPH 1881
ST SSP T +P + S +G S+ S H
Sbjct: 2323 LSEASTTFYSSPRSPT-TTLSPASMTSLGVGEESTTSRSQPGSTH 2366
Score = 48.5 bits (114), Expect = 6e-05
Identities = 141/708 (19%), Positives = 229/708 (32%), Gaps = 82/708 (11%)
Query: 1192 HSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQA 1251
HSR G + + GS G S +SHS+ S D + S++ SS
Sbjct: 3280 HSR----PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT--TLSPGSTTASSLGPEST 3333
Query: 1252 ASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVP 1311
T +L NT G ++ S GS H SP +
Sbjct: 3334 TFHSGPGSTETTLLPDNTTASGLL---EASTPVHSSTGSPHTTLSPAGSTTRQG--ESTT 3388
Query: 1312 QPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDH-------HDSP 1364
P + +PAP S S+ H S S T+ A H SP
Sbjct: 3389 FQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 3448
Query: 1365 ALEVFTEQPP----SPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADD 1420
T P S L + + E G+G+ +S
Sbjct: 3449 VATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGE-------ESTTSH 3501
Query: 1421 DSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDV 1480
S++ T ++ T L++E T + H + S +S++ +
Sbjct: 3502 SSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE---------STA 3552
Query: 1481 KPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKF 1540
SS + T L ++ ++ + ++SGS A T+ + + F
Sbjct: 3553 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT---F 3609
Query: 1541 LPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSP 1600
+ + T S S E + +PGS+ + + S T L + T+
Sbjct: 3610 HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPG----LSRHSTT- 3664
Query: 1601 TPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFA 1660
S+SS ++ ++ P +GS + T + S G
Sbjct: 3665 ------------------SHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTAL-- 3704
Query: 1661 AVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTP 1720
SPG T F SS G +H + D + SSG+ + S +P
Sbjct: 3705 --------SPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 3756
Query: 1721 LNSFS-AFGNSFNLTGE--VFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSW 1777
+ S A S L GE F S + + + SP + P+ +
Sbjct: 3757 RTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 3816
Query: 1778 PASSGSPTHTATSVLGNTS-GLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTEN 1836
PASS + H+ S + ++S TTP S+ +S + + L G+
Sbjct: 3817 PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTT 3876
Query: 1837 SPAPHAPST---SSPADDLGQTYNPWRIWSPTIGRRSSDPWSNSHFPH 1881
+P ST SSP T +P + S +G S+ S H
Sbjct: 3877 TPGLSEASTTFYSSPRSPT-TTLSPASMTSLGVGEESTTSRSQPGSTH 3923
Score = 43.9 bits (102), Expect = 0.001
Identities = 167/794 (21%), Positives = 254/794 (31%), Gaps = 114/794 (14%)
Query: 1178 SSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRA 1237
S G T PG S GS++ P S P S + + A + ++
Sbjct: 1211 SGRGESTTSRISPG-STEITTLPGSTTTPGLSEASTTFYS-SPRSPTTTLSPASMTSLGV 1268
Query: 1238 KNSSSTSSRTSAQAASSQS-ANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHS 1296
S+TS S+ S A+ T+P + + +T + G + H
Sbjct: 1269 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEE 1328
Query: 1297 PLEQHPQPP----------------------LPPPVPQPQEPQPERLSPAPLAHPSHPER 1334
P H +P P Q P L+ A L S
Sbjct: 1329 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFP 1388
Query: 1335 ASSARHSSEDSDITSLIEAM-DKDFDHHDSPALEVFTEQPPSPL-PKSKGKGKPLQRKVK 1392
+SS ++ S S + + SP+ T P SP P K +
Sbjct: 1389 SSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPR 1448
Query: 1393 PP--------------KKQEEKEKKGKGKPQEDELKDSLADDDSSS--TTTETSNPDTEP 1436
P ++ G DS D S TT+ +S TE
Sbjct: 1449 SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEA 1508
Query: 1437 LLK--EDTEKQKGKQAMP---EKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTP 1491
L T G+Q+ ++E + + + ++ PT SL TP
Sbjct: 1509 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 1568
Query: 1492 PL--------ESKQRRNLPSK---IPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKF 1540
ES ++ PS P P T+ + S A +
Sbjct: 1569 ASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT 1628
Query: 1541 LPNSQELGNTSSSEGEKDS---PPPEWDSVPVHKP-----GSSTDSLYKLSLQTLNADIF 1592
L S+E SS G + P SV V +P S + L T A +
Sbjct: 1629 LGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 1688
Query: 1593 LKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAAS--L 1650
K +P SP +P + G S +++S S P GS H S +
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPASTTSSGV--SEESTTSHSRP------GSTHTTAFPGSTTM 1740
Query: 1651 PGKNGNPTFAAVTAGYDK---SPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLW 1707
PG + T + + G SPG + + T F SS G + + D + +SGL
Sbjct: 1741 PGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLL 1800
Query: 1708 SPVSNPSSPDFTPLNSFSAFGNSFNLTGE--VFSKLGLSRSCNQASQRSWNEFNSGPSYL 1765
+ S +P + S G S GE F S+ A + + F +
Sbjct: 1801 EASTPVHSSTGSPHTTLSPAG-STTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS 1859
Query: 1766 WESPATDPSPSWPASS-------------GSPTHTATS---VLGNTSGLWSTTPFSSSIW 1809
SP++ P+ + ASS SP TAT+ TSGL S+ +
Sbjct: 1860 HGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE----ESTAY 1915
Query: 1810 SSNLSSALPFTTPANTLASIGLMGTENSPAPHAPST---SSPADDLGQTYNPWRIWSPTI 1866
S+ S P ++ AS +E S H+ +T SSP + PT
Sbjct: 1916 HSSPGSTQTMHFPESSTAS---GRSEESRTSHSSTTHTISSPPSTTSAL-----VEEPTS 1967
Query: 1867 GRRSSDPWSNSHFP 1880
S + +HFP
Sbjct: 1968 YHSSPGSTATTHFP 1981
Score = 43.5 bits (101), Expect = 0.002
Identities = 141/691 (20%), Positives = 224/691 (32%), Gaps = 46/691 (6%)
Query: 1178 SSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRA 1237
S G T PG S GS++ P S P S + + A + ++
Sbjct: 3851 SGRGESTTSRISPG-STEITTLPGSTTTPGLSEASTTFYS-SPRSPTTTLSPASMTSLGV 3908
Query: 1238 KNSSSTSSRTSAQAASSQS-ANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHS 1296
S+TS S+ S A+ T+P + + +T + G +
Sbjct: 3909 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREE 3968
Query: 1297 PLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERA--------SSARHSSEDSDIT 1348
P H +P ++ L+ A P P ++A E +
Sbjct: 3969 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFP 4028
Query: 1349 SLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKP 1408
S + S + E PS L S + L P E K P
Sbjct: 4029 SSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE-KSTTFYTSP 4087
Query: 1409 QEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKK 1468
+ + S A SS + E+S ++P T E S Q S +
Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTE 4147
Query: 1469 LLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSK 1528
P SSL T S + +P T +TSG + T
Sbjct: 4148 ATLS----PGSTTASSLGQQSTT-FHSSPGDTETTLLPDDT-ITSGLVEASTPTHSSTGS 4201
Query: 1529 LVDNRPPALAKFLPNSQELGNTSSSEGEKDSPP--PEWDSVPVH-------KPGSSTDSL 1579
L PA + +E S D+ P P +VPV +P S+ +
Sbjct: 4202 LHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTH 4261
Query: 1580 YKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNG 1639
+ S TL R T SP A S +S++ ++ P +G
Sbjct: 4262 FSASSTTLG-------RSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI---SSG 4311
Query: 1640 SKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGG--NGFAKVSSNKTGFSSSLGISHAPVD 1697
S T+ +LPG + + + SP + S+ +G S SH+
Sbjct: 4312 S----TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 4367
Query: 1698 SDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNE 1757
S + + + + S +S + + + S LG + +S S E
Sbjct: 4368 SMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGS-TE 4426
Query: 1758 FNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSAL 1817
P S + S +S+GSP HT S G+T+ +T F S S + + A
Sbjct: 4427 TTLLPDNTTASGLLEASTPVHSSTGSP-HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 4485
Query: 1818 PFTTPANTLASIGLMGTENS-PAPHAPSTSS 1847
P TT A S G+ +S P H ++S+
Sbjct: 4486 PTTTSAFVELSTTSHGSPSSTPTTHFSASST 4516
Score = 43.1 bits (100), Expect = 0.003
Identities = 154/700 (22%), Positives = 233/700 (33%), Gaps = 112/700 (16%)
Query: 1215 GPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGH 1274
G S +SHS S D + S+ S SS KT+ L NT T G
Sbjct: 331 GVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRL--PDNTTTSGL 388
Query: 1275 TAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPER 1334
++ S GS H SP P P + SPAP S +
Sbjct: 389 L---EASTPVHSSTGSPHTTLSPSSSTTHEG--EPTTFQSWPSSKDTSPAPSGTTSAFVK 443
Query: 1335 ASSARHSSEDSDITSLIEAMDKDFDH-------HDSPALEVFTEQPPSPLPKSKGKGKPL 1387
S+ HSS S T+ A H H SP T PP + G +
Sbjct: 444 LSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATT--PPPARSATSGHVEES 501
Query: 1388 QRKVKPPKKQE----EKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKE--- 1440
+ P + + G +E A S+T T++S P T L
Sbjct: 502 TAYHRSPGSTQTMHFPESSTTSGHSEES------ATFHGSTTHTKSSTPSTTAALAHTSY 555
Query: 1441 -----DTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTP-PLE 1494
TE + + SE S+ S + +P PS L TP P+
Sbjct: 556 HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAM-ATTVLPAGSTPSVLVGDSTPSPIS 614
Query: 1495 SKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSE 1554
S + T GS ++ K T+ R P LP S S
Sbjct: 615 SGS---------METTALPGSTTKPGLSEKSTTFYSSPRSPD-TTHLPASMTSSGVSEES 664
Query: 1555 GEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPC-- 1612
S P + PGS+T + L+ + PT + SP +
Sbjct: 665 TTSHSRPGSTHTTAF--PGSTT-------MPGLSQESTASHSSPGPTDTTLSPGSTTASS 715
Query: 1613 ------PFVAR-GSYSSIV---NSSSSSDPKIKQPNGSKHK-----LTKAASLPGKNGNP 1657
F +R GS + + N+++S + P S + L+ A S + +
Sbjct: 716 LGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST 775
Query: 1658 TFAAVTAGYDKSPG----GNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGL-WSPVSN 1712
TF + + D P + F + S+ G SS+ +H S S +SGL +
Sbjct: 776 TFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI---SARSTTSGLVEESTTY 832
Query: 1713 PSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATD 1772
SSP T F + E + + ++ + + P+ SP +
Sbjct: 833 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST 892
Query: 1773 PSPSWPASSGS----------------------PTHTATSVLGNTSGLWSTTPFSSSIWS 1810
+ +P SS + P + TSVL S +T+P SS
Sbjct: 893 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES---TTSPISS---G 946
Query: 1811 SNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTS-SPA 1849
S ++ALP +T T + T +P +P+T+ SPA
Sbjct: 947 SMETTALPGST---TTPGLSERSTTFHSSPRSPATTLSPA 983
Score = 43.1 bits (100), Expect = 0.003
Identities = 136/704 (19%), Positives = 227/704 (32%), Gaps = 102/704 (14%)
Query: 1192 HSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQA 1251
HSR G + + GS G S +SHS+ D + S++ SS
Sbjct: 668 HSR----PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDT--TLSPGSTTASSLGPEYT 721
Query: 1252 ASSQSANKTSPLVLDSNTVTQGHT-AGRKSKGAKQSQHGSQHHAHSPLEQ------HPQP 1304
T +L NT G A + +S H + A S Q H P
Sbjct: 722 TFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWP 781
Query: 1305 PLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSP 1364
P P + P+ +H S ++ H S S + L+E + +H SP
Sbjct: 782 SSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT--HISARSTTSGLVE---ESTTYHSSP 836
Query: 1365 ALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSS 1424
P S +G+ +S S++
Sbjct: 837 GSTQTMHFPESDTTSGRGE-------------------------------ESTTSHSSTT 865
Query: 1425 TTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSS 1484
T ++ T L++E T + H + S +S++ + SS
Sbjct: 866 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE---------STASHSS 916
Query: 1485 LELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNS 1544
+ T L ++ ++ + ++SGS A T+ + R F +
Sbjct: 917 QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT---FHSSP 973
Query: 1545 QELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPAS 1604
+ T S S E + +PGS+ + + S T L + T+
Sbjct: 974 RSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPG----LSRHSTT----- 1024
Query: 1605 PSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTA 1664
S+SS ++ ++ P +G + T + S G
Sbjct: 1025 --------------SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTAL------ 1064
Query: 1665 GYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSF 1724
SPG T F S+ G +H + D + SSG+ + S +P +
Sbjct: 1065 ----SPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 1120
Query: 1725 S-AFGNSFNLTGE--VFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASS 1781
S A S L GE F S + + + SP + P+ +PASS
Sbjct: 1121 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 1180
Query: 1782 GSPTHTATSVLGNTS-GLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAP 1840
+ H+ S + ++S TTP S+ +S + + L G+ +P
Sbjct: 1181 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL 1240
Query: 1841 HAPST---SSPADDLGQTYNPWRIWSPTIGRRSSDPWSNSHFPH 1881
ST SSP T +P + S +G S+ S H
Sbjct: 1241 SEASTTFYSSPRSPT-TTLSPASMTSLGVGEESTTSRSQPGSTH 1283
Score = 40.0 bits (92), Expect = 0.021
Identities = 139/691 (20%), Positives = 222/691 (32%), Gaps = 46/691 (6%)
Query: 1178 SSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRA 1237
S G T PG S GS++ P S P S + + A + ++
Sbjct: 2768 SGRGESTTSRISPG-STEITTLPGSTTTPGLSEASTTFYS-SPRSPTTTLSPASMTSLGV 2825
Query: 1238 KNSSSTSSRTSAQAASSQS-ANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHS 1296
S+TS S+ S A+ T+P + + +T + G +
Sbjct: 2826 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEE 2885
Query: 1297 PLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERA--------SSARHSSEDSDIT 1348
P H +P ++ L+ A P P ++A E +
Sbjct: 2886 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFP 2945
Query: 1349 SLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKP 1408
S + S + E PS L S + L P E K P
Sbjct: 2946 SSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE-KSTTFYTSP 3004
Query: 1409 QEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKK 1468
+ + S A SS + E+S ++P T E S Q S +
Sbjct: 3005 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTE 3064
Query: 1469 LLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSK 1528
P SSL T S + +P T +TSG + T
Sbjct: 3065 ATLS----PGSTTASSLGQQSTT-FHSSPGDTETTLLPDDT-ITSGLVEASTPTHSSTGS 3118
Query: 1529 LVDNRPPALAKFLPNSQELGNTSSSEGEKDSPP--PEWDSVPVH-------KPGSSTDSL 1579
L PA + +E S D+ P P + PV +P S+ +
Sbjct: 3119 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 3178
Query: 1580 YKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNG 1639
+ S TL R T SP A S +S++ ++ P +G
Sbjct: 3179 FSASSTTLG-------RSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPI---SSG 3228
Query: 1640 SKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGG--NGFAKVSSNKTGFSSSLGISHAPVD 1697
S T+ +LPG + + + SP + S+ +G S SH+
Sbjct: 3229 S----TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 3284
Query: 1698 SDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNE 1757
S + + + + S +S + + + S LG + + S E
Sbjct: 3285 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGS-TE 3343
Query: 1758 FNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSAL 1817
P S + S +S+GSP HT S G+T+ +T F S S + + A
Sbjct: 3344 TTLLPDNTTASGLLEASTPVHSSTGSP-HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 3402
Query: 1818 PFTTPANTLASIGLMGTENS-PAPHAPSTSS 1847
P TT A S G+ +S P H ++S+
Sbjct: 3403 PTTTSAFVELSTTSHGSPSSTPTTHFSASST 3433
Score = 34.7 bits (78), Expect = 0.90
Identities = 40/169 (23%), Positives = 61/169 (36%), Gaps = 21/169 (12%)
Query: 1199 AGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSAN 1258
+G + GS G S + HS+ +S + A +++ S S SS A
Sbjct: 4668 SGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT 4727
Query: 1259 KTSPLVLDSNT--VTQGHTAGRKSKGAKQSQH-----------GSQHHAHSPLEQHPQPP 1305
T+P S T + + TA S G+ Q+ H +HS P
Sbjct: 4728 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 4787
Query: 1306 LPPPVPQPQEPQPERLSPAPLAHPSHPERA--------SSARHSSEDSD 1346
+EP SP +A PE + S+A HSS D++
Sbjct: 4788 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTN 4836
Score = 32.7 bits (73), Expect = 3.4
Identities = 33/134 (24%), Positives = 50/134 (37%), Gaps = 10/134 (7%)
Query: 271 PPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLD 330
P +G +F SR A HT + S TE E T PG +ST+
Sbjct: 2403 PTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE--------ESTAFPGSPASTQTGL 2454
Query: 331 FGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLKASESKYTKVAS 390
TL T DL + +SG+ ++ R T + P L S ++ T +
Sbjct: 2455 PATLTTADLGEESTTFPSSSGSTGTTLSPARST--TSGLVGESTPSRLSPSSTETTTLPG 2512
Query: 391 ISFDASKAKKPSQF 404
S ++K + F
Sbjct: 2513 SPTTPSLSEKSTTF 2526
Score = 32.3 bits (72), Expect = 4.5
Identities = 95/452 (21%), Positives = 155/452 (34%), Gaps = 60/452 (13%)
Query: 1422 SSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVK 1481
SS T+ + T +K T + P H S S S++ T V
Sbjct: 426 SSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE--------STPVH 477
Query: 1482 PSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFL 1541
S + TPP P++ + TSG + + P +
Sbjct: 478 SSPVATATTPP---------PAR-----SATSGHVEESTAYHRSPGSTQTMHFPESSTTS 523
Query: 1542 PNSQEL----GNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQ 1597
+S+E G+T+ ++ S H ST++ + T++ R
Sbjct: 524 GHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG------RS 577
Query: 1598 TSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNP 1657
+ SP A + GS S++ S+ P +GS + +LPG P
Sbjct: 578 EESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPI---SSGSM----ETTALPGSTTKP 630
Query: 1658 TFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSS-GLWSPVSNPSSP 1716
+ + + SP S + T +S+ S +S S S G + P S
Sbjct: 631 GLSEKSTTFYSSPR-------SPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGST 683
Query: 1717 DFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSP- 1775
L+ S +S G + L + + + F+S P + D +
Sbjct: 684 TMPGLSQESTASHSS--PGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTA 741
Query: 1776 ------SWPASSGSPT-HTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLAS 1828
S P S + + HT S G+T+ +T F S S + A P TT A S
Sbjct: 742 SGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPS 801
Query: 1829 IGLMGTENS-PAPH--APSTSSPADDLGQTYN 1857
G+ +S P H A ST+S + TY+
Sbjct: 802 TTSHGSPSSIPTTHISARSTTSGLVEESTTYH 833
Score = 31.2 bits (69), Expect = 10.0
Identities = 32/129 (24%), Positives = 49/129 (37%), Gaps = 10/129 (7%)
Query: 276 KGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLR 335
+G +F SR A HT + S TE E T PG +ST+ TL
Sbjct: 2882 RGEEPTTFHSRPASTHTTLFTEDSTTSGLTE--------ESTAFPGSPASTQTGLPATLT 2933
Query: 336 TQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLKASESKYTKVASISFDA 395
T DL + +SG+ ++ R T + P L S ++ T +
Sbjct: 2934 TADLGEESTTFPSSSGSTGTTLSPARST--TSGLVGESTPSRLSPSSTETTTLPGSPTTP 2991
Query: 396 SKAKKPSQF 404
S ++K + F
Sbjct: 2992 SLSEKSTTF 3000
Score = 31.2 bits (69), Expect = 10.0
Identities = 36/145 (24%), Positives = 54/145 (37%), Gaps = 13/145 (8%)
Query: 263 GTRKLWEIPPYETKGVMR---ASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTA 319
G+ + P T V R +F SR A HT + S TE E T
Sbjct: 3949 GSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE--------ESTAF 4000
Query: 320 PGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLK 379
PG +ST+ TL T DL + +SG+ ++ R T + P L
Sbjct: 4001 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST--TSGLVGESTPSRLS 4058
Query: 380 ASESKYTKVASISFDASKAKKPSQF 404
S ++ T + S ++K + F
Sbjct: 4059 PSSTETTTLPGSPTTPSLSEKSTTF 4083
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 58.5 bits (140), Expect = 6e-08
Identities = 46/160 (28%), Positives = 73/160 (45%), Gaps = 14/160 (8%)
Query: 1236 RAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAH 1295
+ K SS+ S +S++++SS S + + + S +GH GR+ K H A
Sbjct: 694 KMKGFSSSESESSSESSSSDSEDSETEMAPKSKK--KGHP-GREQKKHHHHHHQQMQQAP 750
Query: 1296 SPL-EQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAM 1354
+P+ +Q P PP PP P P PQ ++ P P PS P++A+ A SS I + + +
Sbjct: 751 APVPQQPPPPPQQPPPPPP--PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVL 808
Query: 1355 DKD-----FD---HHDSPALEVFTEQPPSPLPKSKGKGKP 1386
+ FD H P L + + P LP+ P
Sbjct: 809 EPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTP 848
Score = 52.0 bits (123), Expect = 5e-06
Identities = 76/331 (22%), Positives = 121/331 (36%), Gaps = 39/331 (11%)
Query: 1302 PQPPLPP--PVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSD---ITSLIEAMDK 1356
P P P V P P P ++ P + S + +S + S++DS+ L E ++
Sbjct: 458 PDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQ 517
Query: 1357 DFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQE-EKEKKGKGK--PQEDEL 1413
H+ A QP PK K K K ++K K +K+E E+ KK K K P +
Sbjct: 518 LKAVHEQLAA---LSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTK 574
Query: 1414 KDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIK 1473
K++ ++ + S P + + E + + EK + + K +KL +
Sbjct: 575 KNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVV 634
Query: 1474 KEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNR 1533
I + E + + P +I + S R ++ TS L R
Sbjct: 635 HIIQS--------------REPSLKNSNPDEIEIDFETLKPSTLRELERYV-TSCLRKKR 679
Query: 1534 PPALAK--FLPNSQELGNTSSSEGE-------KDSPPPEWDSVPVHK----PGSSTDSLY 1580
P K + S ++ SSSE E DS E + P K PG +
Sbjct: 680 KPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHH 739
Query: 1581 KLSLQTLNADIFLKQRQTSPTPASPSPPAAP 1611
Q + +Q P P P PP P
Sbjct: 740 HHHHQQMQQAPAPVPQQPPPPPQQPPPPPPP 770
Score = 44.7 bits (104), Expect = 9e-04
Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 13/116 (11%)
Query: 1302 PQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHH 1361
P PP P P P P PQP + P +A P + D+ + I+ + H
Sbjct: 252 PVPPQPQPPPAPA-PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI------H 304
Query: 1362 DSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSL 1417
+ P+L PP P G+ + R VKPPKK ++ + ++ + L
Sbjct: 305 EPPSL------PPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQL 354
Score = 40.8 bits (94), Expect = 0.013
Identities = 47/202 (23%), Positives = 69/202 (34%), Gaps = 26/202 (12%)
Query: 1285 QSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSP------APLAHPSHPERASSA 1338
Q S H P Q QPP PPP QP PQP + +P H S P
Sbjct: 1000 QPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHL 1059
Query: 1339 RHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQ---------PPSPLPKSKG------- 1382
R + I S + + H P V ++ P PL K
Sbjct: 1060 REAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPI 1119
Query: 1383 -KGKPLQRKVKP-PKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKE 1440
+ +P ++P P K E K PQ E+K + + P P +
Sbjct: 1120 IRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAP--DK 1177
Query: 1441 DTEKQKGKQAMPEKHESEMSQV 1462
D +KQ+ K + K + ++ +
Sbjct: 1178 DKQKQEPKTPVAPKKDLKIKNM 1199
Score = 34.7 bits (78), Expect = 0.90
Identities = 42/213 (19%), Positives = 72/213 (33%), Gaps = 17/213 (7%)
Query: 1298 LEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKD 1357
++ P PPLPPP P P Q + P P P P+ +H +
Sbjct: 950 VQSQPPPPLPPP-PHPSVQQQLQQQPPP-PPPPQPQPPPQQQHQPPPRP----VHLQPMQ 1003
Query: 1358 FDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPK--KQEEKEKKGKGKPQEDELKD 1415
F H +QPP P P G+ P + KP + + + K P
Sbjct: 1004 FSTHIQQPPPPQGQQPPHPPP---GQQPPPPQPAKPQQVIQHHHSPRHHKSDPY------ 1054
Query: 1416 SLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKE 1475
S + + +P + + P+K E + V Q ++ +++
Sbjct: 1055 STGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEK 1114
Query: 1476 IPTDVKPSSLELPYTPPLESKQRRNLPSKIPLP 1508
I + + S P P K ++ + + LP
Sbjct: 1115 IHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLP 1147
Score = 31.2 bits (69), Expect = 10.0
Identities = 33/170 (19%), Positives = 67/170 (39%), Gaps = 11/170 (6%)
Query: 1302 PQPPLPP-----PVPQPQEPQPERLSPA-PLAHPSH---PERASSARHSSEDSDITSLIE 1352
P+PP P PV PQ P+ + + P+ P P + + + T +
Sbjct: 1131 PEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190
Query: 1353 AMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDE 1412
D + S A + + P +P +K ++ + +++EE+EK K + + E
Sbjct: 1191 KKDLKIKNMGSWA-SLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAE 1249
Query: 1413 L-KDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQ 1461
K+ L + S E + +E +Q+ +Q ++ + + Q
Sbjct: 1250 KEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQ 1299
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 57.8 bits (138), Expect = 1e-07
Identities = 77/289 (26%), Positives = 117/289 (40%), Gaps = 55/289 (19%)
Query: 1599 SPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPT 1658
SPTP SP P P++ PG +P+
Sbjct: 1566 SPTPGSPGSPGPSSPYIPS---------------------------------PGGAMSPS 1592
Query: 1659 FAAVTAGYD-KSPGGNGFAKVSSNKTGFS-SSLGISHAPVDSDGSDSSGLWSPVS---NP 1713
++ + Y+ +SPGG S + T S S S++P + S +S +SP S +P
Sbjct: 1593 YSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSP 1652
Query: 1714 SSPDFTPLN-SFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATD 1772
+SP ++P + S+S S++ T +S S S S + PSY SP+
Sbjct: 1653 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-----TSPSYSPTSPSYS 1707
Query: 1773 P-SPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGL 1831
P SPS+ +S S + T+ S TS +S T S S S N S P TP + S
Sbjct: 1708 PTSPSYSPTSPSYSPTSPS-YSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYS--- 1763
Query: 1832 MGTENSPAPHAPSTSSPADDLGQTYNPWRIWSPTIGRRSSDPWSNSHFP 1880
T S +P +P+ + + + T + SP S P S S+ P
Sbjct: 1764 -PTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSP-----SYSPTSPSYSP 1806
Score = 44.7 bits (104), Expect = 9e-04
Identities = 90/358 (25%), Positives = 129/358 (36%), Gaps = 28/358 (7%)
Query: 1482 PSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFL 1541
P+S T P S N P + TS S S + TS P+ +
Sbjct: 1617 PTSPSYSPTSPSYSPTSPNYSPTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS 1675
Query: 1542 PNSQELGNTSSSEGEKDSP--PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTS 1599
P+ + S SP P + P + P S + S S + S
Sbjct: 1676 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1735
Query: 1600 PTPASPSP------PAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGK 1653
PT S SP P +P SYS S S + P P + T + P
Sbjct: 1736 PTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYT-PTSPNYSPTSPSYSPT- 1793
Query: 1654 NGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNP 1713
+P+++ + Y SP + S T S S S +P S S SP +P
Sbjct: 1794 --SPSYSPTSPSY--SPSSPRYTPQSPTYTPSSPSYSPS-SPSYSPTSPKYTPTSPSYSP 1848
Query: 1714 SSPDFTPLN-SFSAFGNSFNLTGEVFSKLG--LSRSCNQASQRSWNEFNSGPSYLWESPA 1770
SSP++TP + +S ++ T +S S + + S S + P Y SP
Sbjct: 1849 SSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPK 1908
Query: 1771 TDP-----SPSWPA-SSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTP 1822
P SP+ P S SPT++ TS G+T +S T S S S P +P
Sbjct: 1909 YSPTSPTYSPTSPKYSPTSPTYSPTSPKGST---YSPTSPGYSPTSPTYSLTSPAISP 1963
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 56.2 bits (134), Expect = 3e-07
Identities = 96/451 (21%), Positives = 151/451 (33%), Gaps = 63/451 (13%)
Query: 1197 CGAGGSSSRPSAG---SHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAAS 1253
CGAG + P++ ++ C H H + + +V +++ S + +
Sbjct: 326 CGAGSAELNPNSEWFENYSLC------HRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGD 379
Query: 1254 SQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQ---------P 1304
+ + + V GH + K Q ++ + ++ PQ P
Sbjct: 380 TPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP 439
Query: 1305 PLPPPVPQPQEPQPE-----------RLSPAPLAHPSHPERASSARHSSEDSDITSLIEA 1353
LPPP P P PE RLSP P P+ P L EA
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASP-----------------LPEA 482
Query: 1354 MDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEK---EKKGKGKPQE 1410
+ +SP E P SP P+S + + PP++ E P+
Sbjct: 483 LHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA 542
Query: 1411 DELKDSLADDDSSSTTTE--TSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKK 1468
L + S E TS P L E+ P ES MS + S +
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE---SPMSPPPEESPMSPPPEAS-R 598
Query: 1469 LLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSK 1528
L +E P + P E P +PP E+ + P P+ S + ++ +
Sbjct: 599 LFPPFEESP--LSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656
Query: 1529 LVDNR---PPALAKFLPNSQELGNTSSSEGEKDSPPPE---WDSVPVHKPGSSTDSLYKL 1582
V +R PP + P +E + E + SPPPE P P S +
Sbjct: 657 PVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM 716
Query: 1583 SLQTLNADIFLKQRQTSPTPASPSPPAAPCP 1613
SL + + + P S P +P P
Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747
Score = 35.8 bits (81), Expect = 0.41
Identities = 99/463 (21%), Positives = 157/463 (33%), Gaps = 92/463 (19%)
Query: 1297 PLEQHPQPPLPPPVPQP---QEPQPER-------LSPAPLA-------HPSHPERASSAR 1339
P P P+ PP P +EP+P+ L+ +A P H R R
Sbjct: 1558 PYVVKPVAPVAPPELVPMKVKEPEPQYFRFEGVWLTETGMALLRNLTMSPLHKRRQRRGR 1617
Query: 1340 ---------HSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRK 1390
SE SD + D D D + E E + K +G P+
Sbjct: 1618 LGLPGEAGLEGSEPSDALGPDDKKDGDLDTDELLKGEGGVEHMECEI-KLEG---PVSPD 1673
Query: 1391 VKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQA 1450
V+P K++ E+ KK K KP + + S T T+ +L D + + A
Sbjct: 1674 VEPGKEETEESKKRKRKPYRPGIGGFMVRQRKSHTRTKKGPAAQAEVLSGDGQPDEVIPA 1733
Query: 1451 -MPEKHESEMSQV---KQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIP 1506
+P + E S ++K ++ KK D+ P+ L+ + K+ +L K
Sbjct: 1734 DLPAEGAVEQSLAEGDEKKKQQRRGRKKSKLEDMFPAYLQEAFF----GKELLDLSRKAL 1789
Query: 1507 LPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSS--EGEKDSPPPEW 1564
+ S K KG P K + ++ + S EG+ D+P PE
Sbjct: 1790 FAVGVGRPSFGLGTPKAKGDGGSERKELPTSQKG-DDGPDIADEESRGLEGKADTPGPED 1848
Query: 1565 DSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIV 1624
V + SP P+ P P P G SS +
Sbjct: 1849 GGV-----------------------------KASPVPSDPEKPGTP----GEGMLSSDL 1875
Query: 1625 NSSSSSD-PKIKQPN---------GSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNG 1674
+ S+ + PK++ + GS+ + PG G+ T P GN
Sbjct: 1876 DRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTPLQRPFLQGGLPLGN- 1934
Query: 1675 FAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPD 1717
+ + S G+ +P D + G +SP P PD
Sbjct: 1935 ----LPSSSPMDSYPGLCQSPF-LDSRERGGFFSP--EPGEPD 1970
Score = 32.7 bits (73), Expect = 3.4
Identities = 103/464 (22%), Positives = 157/464 (33%), Gaps = 106/464 (22%)
Query: 1303 QPPLPPPVPQPQEPQPERLS----PAPLA---------------HPSHPERASSARHSSE 1343
+P L PPVPQP P P ++ P P HPS S+ + E
Sbjct: 2544 EPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGE 2603
Query: 1344 DSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKK 1403
++ L +PPS LP G P ++
Sbjct: 2604 SYGLSPL---------------------RPPSVLPPPAPDGS------LPYLSHGASQRS 2636
Query: 1404 GKGKPQEDELKDSLADDDSSSTTTE---TSNPDTEPLLKEDTEKQKGKQAMPE---KHES 1457
G P E + +D SS T E T +P L + + EKQ+ +Q + E + +
Sbjct: 2637 GITSPVE-KREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQI 2695
Query: 1458 EMSQVKQKSKKLLNIKKEIPTDVKPSSLEL-PYTPPLESKQRRNLP--------SKIPLP 1508
+ + ++Q+ + + P S P +P E R P S + LP
Sbjct: 2696 QRNTLRQEKETAAAAAGAVG---PPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLP 2752
Query: 1509 TAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVP 1568
+ SG +L PPA P+S ++ + G + + P
Sbjct: 2753 PSKLSG-PILGPGSFPSDDRLSRPPPPA----TPSSMDVNSRQLVGGSQ----AFYQRAP 2803
Query: 1569 VHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPT----PASPSPPAAPCPFVARGSYSSIV 1624
PGS L LQ ++ +Q+ T+ T S P+ P P + R + S +
Sbjct: 2804 Y--PGS-------LPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPL 2854
Query: 1625 NSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDK--SPGGNGF-AKVSSN 1681
S+ P +P +PG G F + K PGG F +
Sbjct: 2855 AGISTRLPGPGEP------------VPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQ 2902
Query: 1682 KTGFSSSLGISH--APVDSDGSDSSGLWSPVSNPSSPDFTPLNS 1723
+ F H AP G SGL P PS+P LN+
Sbjct: 2903 RPRFYPVSEDPHRLAPEGLRGLAVSGL--PPQKPSAPPAPELNN 2944
Score = 31.6 bits (70), Expect = 7.6
Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 2/93 (2%)
Query: 1307 PPPVPQPQEPQPER-LSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPA 1365
PP P+PQ P PE + P + PS P A S+ S + L SP
Sbjct: 2381 PPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPV 2440
Query: 1366 LEVFTEQPPSPLPKSKGKGK-PLQRKVKPPKKQ 1397
F P P S+ + + P KPP+ Q
Sbjct: 2441 TPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQ 2473
Score = 31.2 bits (69), Expect = 10.0
Identities = 40/156 (25%), Positives = 62/156 (39%), Gaps = 14/156 (8%)
Query: 1490 TPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSK-LVDNRPPALAKFLPNSQELG 1548
TPP S Q PS++P P++ ++++ GT K P + P + +L
Sbjct: 4308 TPPPSSPQEPKRPSQLPSPSSQLP-TEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLA 4366
Query: 1549 NTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPP 1608
+T S+G PP+ + KP S SL L +N + + Q S P
Sbjct: 4367 DTLFSKGLGPWDPPD-NLAETQKPEQS--SLVPGHLDQVNGQVVPEASQLS---IKQEPR 4420
Query: 1609 AAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKL 1644
PC A+ V ++ +P I P S H L
Sbjct: 4421 EEPCALGAQS-----VKREANGEP-IGAPGTSNHLL 4450
Score = 31.2 bits (69), Expect = 10.0
Identities = 19/41 (46%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Query: 1296 SPLEQHP-QPPLPPPVPQPQEPQPERLSPAPLAHPSHPERA 1335
SPL P PP P V P EP E P+PL S PE A
Sbjct: 4919 SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 55.5 bits (132), Expect = 5e-07
Identities = 119/646 (18%), Positives = 220/646 (34%), Gaps = 61/646 (9%)
Query: 1222 SSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSK 1281
+ H R + + + RT+ + + A T +N T AG
Sbjct: 348 TEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTEN 407
Query: 1282 GAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQP-------ERLSPAPLAHPSHPER 1334
+ + P E + P P EP E +P+P H ER
Sbjct: 408 REMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGER 467
Query: 1335 --------ASSARHSSEDSDITSLIE-----AMDKDFDHHDSPALEVFTEQPPSPLP--K 1379
SS+ S+E + T L + + ++ + A E T P P +
Sbjct: 468 TPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRE 527
Query: 1380 SKGKGKPLQRKVKPPKKQE----EKEKKGKGKPQEDELKDSLADDDSSSTTTE-TSNPDT 1434
+ K V+P + +E EK +P E+ + A++ ++S++ E T + +
Sbjct: 528 TTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGER 587
Query: 1435 EPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLE 1494
PL E+T P E ++ + ++K E + + L T P
Sbjct: 588 TPLANENT--------TPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSL 639
Query: 1495 SKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSE 1554
++ N + P T+ S + + + T +N P+ A+ N + N
Sbjct: 640 AEPTEN-GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTAN----- 693
Query: 1555 GEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPF 1614
E +P P + + +L+ T N + ++ TS +PA P+ PF
Sbjct: 694 -ENTTPSPAGPTENREMTANEKTTLFPAE-PTENRERTANEKTTS-SPAEPTENGQRTPF 750
Query: 1615 VARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNG 1674
+ SS S+ ++ + P +++ A P +N T T + P N
Sbjct: 751 ANEKTTSS---SAEPTEHGERTPLANENTTLSPAG-PTENRERTANEKTTPFPAEPTENR 806
Query: 1675 FAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLT 1734
+ N T + ++ D + L + + PS + T + F N +
Sbjct: 807 ERTANENTTPSPAQ--------PTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTS 858
Query: 1735 GEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGN 1794
R+ + + + P+ E A + + +PA PT S
Sbjct: 859 SSAEPTEHAERT--PLANENTTSSPAEPTENRERTANEKTTQFPA---EPTENRESTANE 913
Query: 1795 TSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAP 1840
+ + P + W++N ++ L P LM EN AP
Sbjct: 914 KTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAP 959
Score = 40.4 bits (93), Expect = 0.016
Identities = 124/677 (18%), Positives = 237/677 (35%), Gaps = 65/677 (9%)
Query: 1215 GPSVHPHSSHSNRNS-ADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQG 1273
GP+ + ++ + + + + VE + +++ T + A +++ +T P + T +
Sbjct: 521 GPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRT-PFANEKTTSSSA 579
Query: 1274 HTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAH----P 1329
+ +++ + A P E + P P EP E PLA+ P
Sbjct: 580 EPTEHGERTPLANENTTPSPAE-PTENRERTANEKTTPSPAEPT-ENGDRTPLANEKTTP 637
Query: 1330 SHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQR 1389
S E + + + ++ T+ A + + A E T PSP ++ + +
Sbjct: 638 SLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTT---PSPAEPTENRERTANE 694
Query: 1390 KVKP----PKKQEE---KEKKGKGKPQEDELKDSLADDDSSSTTTE-TSNPDTEPLLKED 1441
P P + E EK + E ++ A++ ++S+ E T N P E
Sbjct: 695 NTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEK 754
Query: 1442 TEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTP----PLESKQ 1497
T A P +H + + + PT+ + + TP P E+++
Sbjct: 755 TTSSS---AEPTEHGERTPLANENT----TLSPAGPTENRERTANEKTTPFPAEPTENRE 807
Query: 1498 RRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEG-E 1556
R + P P T K T L + P K P + E +SS+E E
Sbjct: 808 RTANENTTPSPAQPTENGDRTPLANEKTTPSLAE--PTENGKRTPFANEKTTSSSAEPTE 865
Query: 1557 KDSPPPEWDSVPVHKPGSSTDSLYKLSLQ---------TLNADIFLKQRQTSPTPASPSP 1607
P + P T++ + + + T N + ++ T+P PA P+
Sbjct: 866 HAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEK-TTPFPAEPTE 924
Query: 1608 ----------PAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNP 1657
+P + ++ + P +Q + ++ A++ G+
Sbjct: 925 NREWTANENTTLSPAEPTEHEEMTPLMVDENLQAP-FRQGSCAERPKDICATVASTTGSE 983
Query: 1658 TFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPD 1717
+ A + + A +++ T ++ + PV S ++ + VS P +
Sbjct: 984 SSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPVTAS 1043
Query: 1718 FTPLNSFSAFGNSFNLT-----GEVFSKLGLSRSCN-QASQRSWNEFNSGPSYLWESPAT 1771
L S AF N T V + S S N A + + +E E
Sbjct: 1044 ILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASEDTTV 1103
Query: 1772 DPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGL 1831
S A+ P HTAT +T +T S+++ +N S + T +
Sbjct: 1104 STQTSVIAAESVP-HTATKTPTDT----TTASVSATVPKNNTLSVITSTPSTAPNTASKT 1158
Query: 1832 MGTENSPAPHAPSTSSP 1848
M T + + TS P
Sbjct: 1159 MTTASKTTTTSTITSLP 1175
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 55.1 bits (131), Expect = 6e-07
Identities = 104/484 (21%), Positives = 166/484 (34%), Gaps = 81/484 (16%)
Query: 1296 SPLEQHPQPPLPPP-----------------------VPQPQEPQPERLSPAPLAHPSHP 1332
+P++ P PP PPP VP P P+ + + +P PSH
Sbjct: 1960 TPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSH- 2018
Query: 1333 ERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVK 1392
S + ED I S + DFD+ + ++ F P +GK R+
Sbjct: 2019 ---SFSAVFDEDKPIAS-SGTYNLDFDNIE--LVDTFQTLEPRASDAKNQEGKVNTRRKS 2072
Query: 1393 PPKKQEEKE---------------KKGKGKPQEDELKD---SLADDDSSSTTTETSNPDT 1434
K G P+ L S +SST T P
Sbjct: 2073 TDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 2132
Query: 1435 EPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLE 1494
L K+ T K K + P K +Q + + L+ + + ++ K S + P
Sbjct: 2133 PSLKKKQTTK-KPTETPPVKE----TQQEPDEESLVPSGENLASETKTESAKTEGPSPAL 2187
Query: 1495 SKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLP--NSQELGNT-- 1550
++ P+ P + V N PP K LP + E G
Sbjct: 2188 LEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTP 2247
Query: 1551 SSSEGEKDSP---------------PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLK- 1594
S S G++DSP WD+ + P + ++ L K
Sbjct: 2248 SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKT 2307
Query: 1595 QRQTSPTPAS-PSPPAAPCPF-VARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPG 1652
+ TPAS P PA P +A+G+Y+ ++ DP P S K+ ++ LP
Sbjct: 2308 PEKLDNTPASPPRSPAEPNDIPIAKGTYTFDID--KWDDPNF-NPFSSTSKMQESPKLPQ 2364
Query: 1653 KNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSN 1712
++ N F T P +K S+ + +S I + ++++G D GL P
Sbjct: 2365 QSYN--FDPDTCDESVDPFKTS-SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKK 2421
Query: 1713 PSSP 1716
+P
Sbjct: 2422 KKTP 2425
Score = 32.7 bits (73), Expect = 3.4
Identities = 97/471 (20%), Positives = 152/471 (32%), Gaps = 60/471 (12%)
Query: 1219 HPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTV-------- 1270
HP SS ++ +A + A +SSR S A + + V+D+ V
Sbjct: 417 HPASSLASFPAAQIPI--AVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSD 474
Query: 1271 --TQG-HTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLA 1327
++G H G + S H ++ QP +PPP P P+E Q + P
Sbjct: 475 LGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGVPPP-PLPKE-QSHEVQPGAPP 532
Query: 1328 HPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPL 1387
P + SAR +D + H DS + V E SP GK
Sbjct: 533 PPLPKAPSESARGPPGPTDGAKV---------HEDSTSPAVAKEGSRSPGDSPGGK---- 579
Query: 1388 QRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKG 1447
+ +PP + +G+ +D D S + + P +KG
Sbjct: 580 EEAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKG 639
Query: 1448 KQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPL 1507
+ S+ ++ +++ P P P + L K P
Sbjct: 640 GAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIWEGSGLQPKCP- 698
Query: 1508 PTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNT------SSSEGEKDSPP 1561
T + R S+ D P +A+ P +QE +T S +GE
Sbjct: 699 DTLQSREGLGRMESFLTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKMGSCDGEGLLTS 758
Query: 1562 PEWDSVP------------VHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPA 1609
P+ P V P + L L L L Q Q P+
Sbjct: 759 PDQPRGPACDASRQEFHAGVPHPPQGENLAADLGLTAL----ILDQDQ-------QGIPS 807
Query: 1610 APCPFVARGSYSS--IVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPT 1658
P RG+ S +++S P QP S + K + P +NG T
Sbjct: 808 CPGEGWIRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKEQAQPPENGKET 858
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 55.1 bits (131), Expect = 6e-07
Identities = 104/484 (21%), Positives = 166/484 (34%), Gaps = 81/484 (16%)
Query: 1296 SPLEQHPQPPLPPP-----------------------VPQPQEPQPERLSPAPLAHPSHP 1332
+P++ P PP PPP VP P P+ + + +P PSH
Sbjct: 38 TPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSH- 96
Query: 1333 ERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVK 1392
S + ED I S + DFD+ + ++ F P +GK R+
Sbjct: 97 ---SFSAVFDEDKPIAS-SGTYNLDFDNIE--LVDTFQTLEPRASDAKNQEGKVNTRRKS 150
Query: 1393 PPKKQEEKE---------------KKGKGKPQEDELKD---SLADDDSSSTTTETSNPDT 1434
K G P+ L S +SST T P
Sbjct: 151 TDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 210
Query: 1435 EPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLE 1494
L K+ T K K + P K +Q + + L+ + + ++ K S + P
Sbjct: 211 PSLKKKQTTK-KPTETPPVKE----TQQEPDEESLVPSGENLASETKTESAKTEGPSPAL 265
Query: 1495 SKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLP--NSQELGNT-- 1550
++ P+ P + V N PP K LP + E G
Sbjct: 266 LEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTP 325
Query: 1551 SSSEGEKDSP---------------PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLK- 1594
S S G++DSP WD+ + P + ++ L K
Sbjct: 326 SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKT 385
Query: 1595 QRQTSPTPAS-PSPPAAPCPF-VARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPG 1652
+ TPAS P PA P +A+G+Y+ ++ DP P S K+ ++ LP
Sbjct: 386 PEKLDNTPASPPRSPAEPNDIPIAKGTYTFDID--KWDDPNF-NPFSSTSKMQESPKLPQ 442
Query: 1653 KNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSN 1712
++ N F T P +K S+ + +S I + ++++G D GL P
Sbjct: 443 QSYN--FDPDTCDESVDPFKTS-SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKK 499
Query: 1713 PSSP 1716
+P
Sbjct: 500 KKTP 503
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 55.1 bits (131), Expect = 6e-07
Identities = 104/484 (21%), Positives = 166/484 (34%), Gaps = 81/484 (16%)
Query: 1296 SPLEQHPQPPLPPP-----------------------VPQPQEPQPERLSPAPLAHPSHP 1332
+P++ P PP PPP VP P P+ + + +P PSH
Sbjct: 38 TPVKAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPFRPPSH- 96
Query: 1333 ERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVK 1392
S + ED I S + DFD+ + ++ F P +GK R+
Sbjct: 97 ---SFSAVFDEDKPIAS-SGTYNLDFDNIE--LVDTFQTLEPRASDAKNQEGKVNTRRKS 150
Query: 1393 PPKKQEEKE---------------KKGKGKPQEDELKD---SLADDDSSSTTTETSNPDT 1434
K G P+ L S +SST T P
Sbjct: 151 TDSVPISKSTLSRSLSLQASDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRP 210
Query: 1435 EPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLE 1494
L K+ T K K + P K +Q + + L+ + + ++ K S + P
Sbjct: 211 PSLKKKQTTK-KPTETPPVKE----TQQEPDEESLVPSGENLASETKTESAKTEGPSPAL 265
Query: 1495 SKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLP--NSQELGNT-- 1550
++ P+ P + V N PP K LP + E G
Sbjct: 266 LEETPLEPAVGPKAACPLDSESAEGVVPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTP 325
Query: 1551 SSSEGEKDSP---------------PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLK- 1594
S S G++DSP WD+ + P + ++ L K
Sbjct: 326 SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKT 385
Query: 1595 QRQTSPTPAS-PSPPAAPCPF-VARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPG 1652
+ TPAS P PA P +A+G+Y+ ++ DP P S K+ ++ LP
Sbjct: 386 PEKLDNTPASPPRSPAEPNDIPIAKGTYTFDID--KWDDPNF-NPFSSTSKMQESPKLPQ 442
Query: 1653 KNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSN 1712
++ N F T P +K S+ + +S I + ++++G D GL P
Sbjct: 443 QSYN--FDPDTCDESVDPFKTS-SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKK 499
Query: 1713 PSSP 1716
+P
Sbjct: 500 KKTP 503
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 54.7 bits (130), Expect = 8e-07
Identities = 124/674 (18%), Positives = 233/674 (34%), Gaps = 15/674 (2%)
Query: 1179 SEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAK 1238
S GN N + D S G SS S+ S S S S+ NS+ +
Sbjct: 526 SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585
Query: 1239 NSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPL 1298
+SS +S S+ +++S ++ +S S++ ++ KS +K S + S
Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSD---SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDS 642
Query: 1299 EQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDF 1358
S + + S +SS +S DS +S +
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Query: 1359 DHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLA 1418
D DS ++ S S + + +
Sbjct: 703 DSSDS------SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 1419 DDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPT 1478
D SS ++++S+ + + + S+ S S + +
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 1479 DVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALA 1538
D S+ S + S ++ S S S N + +S D+ + +
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876
Query: 1539 KFLPNSQELGNTSSSEGEKDSP-PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQ 1597
+S + +S+S DS + DS S+DS S + +++
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS-SDSSESSNSSDNSNS 935
Query: 1598 TSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNP 1657
+ + +S S ++ + S SS +SS+SSD + S + S + +
Sbjct: 936 SDSSNSSDSSDSSDSSNSSDSSNSS--DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSD 993
Query: 1658 TFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPD 1717
+ + + + + SSN + S+S S++ SD SDSS S S+ SS
Sbjct: 994 SSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD--SSDSSDSSDS 1051
Query: 1718 FTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSW 1777
NS + +S + S S +++S S + +S S +S + S
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 1778 PASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENS 1837
SS S + +S ++S ++ S+S SS+ S + + +++ S + +S
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDS 1171
Query: 1838 PAPHAPSTSSPADD 1851
S SS + D
Sbjct: 1172 SDSSDSSNSSDSSD 1185
Score = 48.9 bits (115), Expect = 5e-05
Identities = 122/677 (18%), Positives = 234/677 (34%), Gaps = 34/677 (5%)
Query: 1178 SSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSA---DVEN 1234
SS+ + N+ S D +S + SS + S S S + NS+ D +
Sbjct: 647 SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD 706
Query: 1235 VRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHA 1294
+SS +S +++ ++ S S+N + DS+ + + S + S ++
Sbjct: 707 SSDSDSSDSSDSSNSNSSDSDSSNSSDS--SDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 1295 HSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAM 1354
+ ++ S +S++ SS SD + ++
Sbjct: 765 SDSSDSSDS--------SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 1355 DKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELK 1414
D D + S + S S + + D
Sbjct: 817 DSD-SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 1415 DSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKK 1474
S + D S S + S+ ++ D++ + S S + S N
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS 935
Query: 1475 EIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRP 1534
++ SS S + S ++ +S S N+ + +S D+
Sbjct: 936 SDSSNSSDSS--------DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 1535 PALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLK 1594
+ + +S + N+S S DS S + SS S S + ++D
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS--DSSDSSDSSDSSDS 1045
Query: 1595 QRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKN 1654
+ + +S S ++ + S SS +SS SSD + + ++ +
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSS--DSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 1655 GNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPS 1714
+ + + D S N + SS+ + S S S++ SD S+SS +
Sbjct: 1104 DSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Query: 1715 SPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPS 1774
S D + + S +S N + S S + S S + +S S S ++D S
Sbjct: 1162 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS----SDSSDSS 1217
Query: 1775 PSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLA-SIGLMG 1833
S SS S + ++ ++S ++ S+S SS+ S + T+ +N + S G
Sbjct: 1218 DS-SDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSG 1276
Query: 1834 TENSPAPHAPSTSSPAD 1850
N+ + S S +D
Sbjct: 1277 NGNNNGSDSDSDSEGSD 1293
Score = 48.9 bits (115), Expect = 5e-05
Identities = 122/669 (18%), Positives = 224/669 (33%), Gaps = 30/669 (4%)
Query: 1178 SSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRA 1237
SS + ++ S D S + SS+ + S S + +S ++ +
Sbjct: 659 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 718
Query: 1238 KNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSP 1297
NS+S+ S +S + SS S+N + DS+ + + S + S +
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDS--SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDS 776
Query: 1298 LEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMD-- 1355
+ S + + S SS SS SD ++ ++ D
Sbjct: 777 SDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 1356 KDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKD 1415
D DS ++ S S + D
Sbjct: 837 NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSD 896
Query: 1416 SLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKE 1475
S DS S+ + S+ ++ D+ + +S S S N
Sbjct: 897 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 1476 IPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPP 1535
+ +S + + +S N + + S S ++ + +S D+
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSN-------SSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009
Query: 1536 ALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQ 1595
+ + NS + N+S S DS DS S+DS S + ++D
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSS-DSSDSSDSSDSSDS----SDSSNSSDSSDSS 1064
Query: 1596 RQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNG 1655
+ + +S S ++ + S SS NSS SSD + + ++ +
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSS--NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 1656 NPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSS 1715
+ + + D S N SS+ + S S S + SD SDSS S+ SS
Sbjct: 1123 SSDSSDSSDSSDSSDSSN-----SSDSSDSSESSDSSDSSDSSDSSDSSD-----SSDSS 1172
Query: 1716 PDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSP 1775
NS + +S + S S + +S S + +S S S ++D S
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSDSSD 1230
Query: 1776 SWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTE 1835
S +S S + ++ ++ S+ S+ S++ S + + N S +E
Sbjct: 1231 SNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290
Query: 1836 NSPAPHAPS 1844
S + H+ S
Sbjct: 1291 GSDSNHSTS 1299
Score = 48.5 bits (114), Expect = 6e-05
Identities = 101/528 (19%), Positives = 185/528 (35%), Gaps = 35/528 (6%)
Query: 1355 DKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELK 1414
D + D +DS + + Q P + G + +G DE K
Sbjct: 444 DSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANS----ESDNNSSSRGDASYNSDESK 499
Query: 1415 DSL-------ADDDSSSTTTETSNPDT--------EPLLKEDTEKQKGKQAMPEKHESEM 1459
D+ A+DD S +T++T+N D+ + K D+ K K + + +S
Sbjct: 500 DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN 559
Query: 1460 SQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRN 1519
S S + +D S + + +S N + S S +
Sbjct: 560 SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619
Query: 1520 AQKTKGTSKLVDNRPPALAKF---------LPNSQELGNTSSSEGEKDSPPPEWDSVPVH 1570
+ +SK + + +K ++ + ++S+S DS S
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679
Query: 1571 KPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSS 1630
SS S S + N+ +S + +S S ++ S +S +S SS+
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739
Query: 1631 DPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLG 1690
+ S + + S N + + + + + + SSN + S S
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 1691 ISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQA 1750
S + SD SDSS S+ SS +S + +S + S S S N++
Sbjct: 800 SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRS 859
Query: 1751 SQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTA-------TSVLGNTSGLWSTTP 1803
+ ++ + S ++D S S +S+ S + + +S N+S ++
Sbjct: 860 DSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSN 919
Query: 1804 FSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADD 1851
S S SSN S + +N+ S + NS S SS + D
Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967
Score = 47.0 bits (110), Expect = 2e-04
Identities = 112/662 (16%), Positives = 229/662 (34%), Gaps = 48/662 (7%)
Query: 1201 GSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKN----SSSTSSRTSAQAASSQS 1256
GS S+ + + S+ N N+ + +N ++ + S S+ S +S + SS S
Sbjct: 504 GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563
Query: 1257 ANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEP 1316
++ + DSN+ + ++ S + S ++ +
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDS------------- 610
Query: 1317 QPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDF-DHHDSPALEVFTEQPPS 1375
S + + S ++ S++ S+ SD S ++ D + D D+ + S
Sbjct: 611 -----SDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 1376 PLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTE 1435
+ + E +D DSS ++ +++ ++
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 1436 PLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLES 1495
++ + S+ S S + +D SS + +S
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 1496 KQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEG 1555
N + S + S ++ + + N + NS + ++S+S
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDS-----SNSSDSSDSSNSSD 840
Query: 1556 EKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFV 1615
DS DS GS +DS + + + +S S ++
Sbjct: 841 SSDSS----DS----SDGSDSDSSNRSD----------SSNSSDSSDSSDSSNSSDSSDS 882
Query: 1616 ARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGF 1675
+ + SS NSS SSD + S + S N + + + + + + +
Sbjct: 883 SDSNESS--NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 1676 AKVSSNKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTG 1735
+ SS+ + S+S S++ S+ SDSS S S+ SS +S + +S +
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 1736 EVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNT 1795
S S + +S S + +S S +S + S SS S + +S ++
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 1796 SGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLGQT 1855
S ++ S S SS+ S + + +++ S + +S S SS + D +
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 1856 YN 1857
N
Sbjct: 1121 SN 1122
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 54.7 bits (130), Expect = 8e-07
Identities = 102/482 (21%), Positives = 176/482 (36%), Gaps = 82/482 (17%)
Query: 1205 RPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLV 1264
R S K+ G SV P + R ++ + A NSS +SSR+S+ + S S +++
Sbjct: 520 RRSKSPKKKLGVSVSPSRARRRRKTS-ASSASASNSSRSSSRSSSYSGSGSSRSRS---- 574
Query: 1265 LDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPA 1324
++ S ++ S+H S + S P P P P P P S
Sbjct: 575 ---------RSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRP-----SIR 620
Query: 1325 PLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTE-QPPSPLPKSKGK 1383
P+ P + + + + PA T+ P P P G
Sbjct: 621 TKGEPAPPPGKAGEKSVKKPA----------------PPPAPPQATKTTAPVPEPTKPGD 664
Query: 1384 GKPLQRKVKP---PKKQEEKEKKGKG--------KPQEDELKDSLADDDSSSTTTETS-- 1430
+ +RK +P P ++ G G + L S SS+T++ +S
Sbjct: 665 PREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAH 724
Query: 1431 NPDTE--------PLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKP 1482
+ D+E P+ + Q EK +S+ ++ K+ + + P KP
Sbjct: 725 SVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKP 784
Query: 1483 ----SSLELPYT----PPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRP 1534
S + P T PP + +Q + K T + + + ++ + + K D +
Sbjct: 785 PAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDK--DRQS 842
Query: 1535 PALAKFLPNSQELGNTS-SSEGEKDSPPPEWDSVPVHK-PGSSTDSLYKLSLQTLNADIF 1592
P AK S + G+ S G SP PE K P + D +LS Q+ ++
Sbjct: 843 PPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSS-- 900
Query: 1593 LKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLT-KAASLP 1651
+ + P S P A + S ++ S + +KQ + + K A +P
Sbjct: 901 ----KVTSVPGKASDPG------AASTKSGKASTLSRREELLKQLKAVEDAIARKRAKIP 950
Query: 1652 GK 1653
GK
Sbjct: 951 GK 952
Score = 53.9 bits (128), Expect = 1e-06
Identities = 90/423 (21%), Positives = 160/423 (37%), Gaps = 84/423 (19%)
Query: 1172 RRIVGISSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSAD 1231
RR +S + + S S + G+G S SR + S +SS+S+R+S
Sbjct: 540 RRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSS----------YSSYSSRSS-- 587
Query: 1232 VENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQ 1291
++SS + SR+ +++ SS + +P + T+G A K ++S
Sbjct: 588 ------RHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKS----- 636
Query: 1292 HHAHSPLEQHPQPPLPP-------PVPQPQEPQPER-----------------LSPAPLA 1327
+++ PP PP PVP+P +P R LS +
Sbjct: 637 ------VKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSG 690
Query: 1328 HPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPL 1387
S +SS S S ++S+ A H + +++ + SP+ + +
Sbjct: 691 SGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADL-ASPVSSASSRS--- 746
Query: 1388 QRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKG 1447
P + +++KGK K +ED +K+ DSS+ +++ P P + +++
Sbjct: 747 ------PAPAQTRKEKGKSK-KEDGVKEEKRKRDSSTQPPKSAKP---PAGGKSSQQPST 796
Query: 1448 KQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPL 1507
Q P + + V K KL + K + Y P K R++ P
Sbjct: 797 PQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKR-----YEP--SDKDRQSPPPAKRP 849
Query: 1508 PTAMTSGSKSRNAQKTKGTSKLVDNR------PPALA----KFLPNSQELGNTSSSEGEK 1557
T+ GS+ R + G+ K R P A A + P S+ +S G+
Sbjct: 850 NTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKA 909
Query: 1558 DSP 1560
P
Sbjct: 910 SDP 912
Score = 35.8 bits (81), Expect = 0.41
Identities = 74/360 (20%), Positives = 128/360 (35%), Gaps = 65/360 (18%)
Query: 1379 KSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLL 1438
++K K Q + + +K+ EKEK GK KP+ +P
Sbjct: 457 RAKRDEKDRQHRDRDREKEREKEK-GKPKPR---------------------SPQPPSRQ 494
Query: 1439 KEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQR 1498
E +K+ K E ++SK + KK++ V PS +R
Sbjct: 495 AEPPKKEAATTGPQVKRADEWKDPWRRSK---SPKKKLGVSVSPS-----------RARR 540
Query: 1499 RNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQE----LGNTSSSE 1554
R S + +S S SR++ + S +R + + + S G+ S S
Sbjct: 541 RRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSR 600
Query: 1555 GEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPF 1614
SP P S T S ++ S++T + + P+PP P P
Sbjct: 601 SFSSSPSP-----------SPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPP--PAPP 647
Query: 1615 VARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNG 1674
A + + + + DP+ ++ K A + P + T + +G S G+
Sbjct: 648 QATKTTAPVPEPTKPGDPR-----EARRKERPARTPPRRR---TLSGSGSGSGSSYSGSS 699
Query: 1675 FAKVSSNKTGFSSSLGISHAPVDSDGSDSSGLW----SPVSNPSSPDFTPLNSFSAFGNS 1730
S + + SS + + + DS ++ SPVS+ SS P + G S
Sbjct: 700 SRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKS 759
Score = 34.7 bits (78), Expect = 0.90
Identities = 29/129 (22%), Positives = 49/129 (37%), Gaps = 14/129 (10%)
Query: 1309 PVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEV 1368
P Q Q+ + LS P + P E SD+ ++ ++ D H+ L+
Sbjct: 76 PKSQDQDSEVNELSRGPTSSPCEEE--GDEGEEDRTSDLRDEASSVTRELDEHE---LDY 130
Query: 1369 FTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELK--DSLADDDSSSTT 1426
E P P P +Q E+ E+KG+G P+E+ S+ + +S
Sbjct: 131 DEEVPEEPAPA-------VQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAA 183
Query: 1427 TETSNPDTE 1435
E D +
Sbjct: 184 KEKKKEDDD 192
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 54.7 bits (130), Expect = 8e-07
Identities = 101/501 (20%), Positives = 162/501 (32%), Gaps = 113/501 (22%)
Query: 1206 PSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVL 1265
P S + GP P H + + D ++V SS SA A + K SP
Sbjct: 223 PGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSS-----SAPAGAEADGPKASP--- 274
Query: 1266 DSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAP 1325
+ Q ++ L++ PP P P P++ E +PAP
Sbjct: 275 -----------------EARPQIPTKPRVPGKLQELASPPAGRPTPAPRKAS-ESTTPAP 316
Query: 1326 LAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGK 1385
P + + E + +SL+ + P+PK +G K
Sbjct: 317 PT--PRPRSSLQQENLVEQAGSSSLVNGRLHEL-----------------PVPKPRGTPK 357
Query: 1386 PLQRKVKPPKK-------QEEKEKK--------GKGKPQEDELKDSLADDDSSSTTTETS 1430
P + P K Q E +KK G P +D + + + + T+
Sbjct: 358 PSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTA 417
Query: 1431 NPDTEP---LLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLN-----IKKEIPTDVKP 1482
+ +++P +E+ +K++ A P S + + K L+ P K
Sbjct: 418 SLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKR 477
Query: 1483 SSLELPYTPPLESKQRR----NLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALA 1538
+ P PL R PS P P S +A +T G L PPA+
Sbjct: 478 PAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELL---EPPAVP 534
Query: 1539 KFLP-----------NSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTL 1587
K N L SS + P + +P PG + +
Sbjct: 535 KSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRT--------- 585
Query: 1588 NADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSI-----------VNSSSSSDPKIKQ 1636
+ + P PA P A P P + G S + V SS +P ++
Sbjct: 586 -------RGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRK 638
Query: 1637 PNGSKHKLTKAASLPGKNGNP 1657
P+ + TK A+ K P
Sbjct: 639 PSPAASPATKKATKGSKPVRP 659
>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
Length = 987
Score = 54.3 bits (129), Expect = 1e-06
Identities = 143/693 (20%), Positives = 223/693 (32%), Gaps = 105/693 (15%)
Query: 1190 PGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAK---------NS 1240
P SR + SS+R + K+ GPS P SS ++ S E K +S
Sbjct: 141 PSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSS 200
Query: 1241 SSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQ 1300
SST ++ ++A+ T +SN+ + ++G++ + + P +
Sbjct: 201 SSTPLAADKESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLL----------PSRR 250
Query: 1301 HPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDH 1360
Q LPPP P+ S D + + ++ ++ +
Sbjct: 251 GEQLTLPPP----------------------PQLGYSITAEDLDLEKKASLQWFNQALED 288
Query: 1361 HDSPALEVFTEQPPSP-------LPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDEL 1413
A TE PP+ LP + P E KK + P
Sbjct: 289 KSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPC 348
Query: 1414 KDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIK 1473
+S ++TT S P T LL Q G + + S+ L+
Sbjct: 349 PESAG----AATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFD-SKPPTTLLGLIPAP 403
Query: 1474 KEIP-TDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDN 1532
+P TD K PP + P P+ S Q T +S
Sbjct: 404 SMVPATDTK--------APPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPA 455
Query: 1533 RPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSS----TDSLYKLSLQTLN 1588
A F P T+ + EK+ P P SV P SS T S + Q +
Sbjct: 456 ASSASPMFKPIF-----TAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVF 510
Query: 1589 ADI-----------FLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQP 1637
+ + F KQ T T + + P A + + I ++S S+D K
Sbjct: 511 SSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPA 570
Query: 1638 NGSKHKLTKAASLPGKNGNPTFAAVTAGYDK-SPGGNGFAKVSSNKTGFSSSLGISHAPV 1696
G ++S+ T A+ + F + F +
Sbjct: 571 FGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
Query: 1697 DSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWN 1756
+ S S P + SS FS FG++ + S S+ S S
Sbjct: 631 VTTFSQSLPTAVPTATSSSAA-----DFSGFGSTLATSAPATS----SQPTLTFSNTSTP 681
Query: 1757 EFN-----SGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSS 1811
FN S S L P +P P++ A+ G P A L T F SS
Sbjct: 682 TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPAL--------TPSFGSSFTFG 733
Query: 1812 NLSSALPFTTPANTLASIGLMGTENSPAPHAPS 1844
N ++ P T P AS + + P P P+
Sbjct: 734 NSAAPAPATAPTPAPASTIKIVPAHVPTPIQPT 766
Score = 51.2 bits (121), Expect = 9e-06
Identities = 136/643 (21%), Positives = 233/643 (36%), Gaps = 115/643 (17%)
Query: 1277 GRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHP---E 1333
G+++K + GS H A PL + VP P+P L + S +
Sbjct: 70 GQENKRRRHDSSGSGHSAFEPL-------VASGVPASFVPKPGSLKRGLNSQSSDDHLNK 122
Query: 1334 RASSARHSSEDSDITSLIEAMDKDFDHHDSPAL----EVFTEQPPSPLPKSKGKGKPLQR 1389
R+ S+ SS TS I + ++ + +++ PS P S Q
Sbjct: 123 RSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQT 182
Query: 1390 KVKPPKKQEEKE---KKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQK 1446
+P KK E+E P + K+S + + +T + N +++ ++++
Sbjct: 183 PERPAKKIREEELCHHSSSSTPLAAD-KESQGEKAADTTPRKKQNSNSQSTPGSSGQRKR 241
Query: 1447 GKQAMPEKHESEMS-----------------------------QVKQKSKKLLNIKKEIP 1477
Q +P + +++ ++ KS N E P
Sbjct: 242 KVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQALEDKSDAASNSVTETP 301
Query: 1478 TDVKPS---------------SLELPYTPP-LESKQRRNLPSKIPLPTAMTSGSKSRNAQ 1521
+PS SL P T P LES ++ P +P P ++G+ + A
Sbjct: 302 PTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLP-PCPESAGAATTEAL 360
Query: 1522 KTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYK 1581
T L+ PP L S G S + P +P +TD+
Sbjct: 361 SPPKTPSLL---PPL---GLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDT--- 411
Query: 1582 LSLQTLNADIFLKQRQTS-PTPA------------SPSPPAAPCPFVARGSYSSIVNSSS 1628
+ TL A+ K + TS P+PA SPS PAAP A + I +
Sbjct: 412 KAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPP 471
Query: 1629 SSDPKIKQPNGSKHKLT--KAASLPGKNGN--PTFAAVTAGYDKSPGGNGFAKVSSNKTG 1684
S+ + P G T ++SLP PTF V + P +T
Sbjct: 472 KSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG-PPASVPLPAPFFKQTT 530
Query: 1685 FSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLS 1744
++ + AP+ + + ++ +P+++ S T S AFG N S +S
Sbjct: 531 TPATAPTTTAPLFTGLASATSAVAPITSASPS--TDSASKPAFGFGINSV----SSSSVS 584
Query: 1745 RSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPF 1804
+ + A+ S P +P A+S +P + G L +TT
Sbjct: 585 TTTSTATAAS-------------QPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTV 631
Query: 1805 SSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSS 1847
++ +S +L +A+P T + ++ G ++ A AP+TSS
Sbjct: 632 TT--FSQSLPTAVPTATSS---SAADFSGFGSTLATSAPATSS 669
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 53.9 bits (128), Expect = 1e-06
Identities = 72/304 (23%), Positives = 113/304 (37%), Gaps = 42/304 (13%)
Query: 1242 STSSRTSAQAASS-----------QSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGS 1290
STS R Q S Q A+ L S V GH K +Q
Sbjct: 397 STSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQ 456
Query: 1291 QHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITS- 1349
PL HP PPLPPP QP P P A H S P A S++ DI
Sbjct: 457 LPPPPPPLP-HPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPA-----CSQNMDIMHH 510
Query: 1350 --LIEAMDKDFD---HHDSPALEVFTEQPPSPLPKS-KGKGKPLQRKVKPPKKQEEKE-- 1401
+E M KD + P+L++ + P L ++ G+ + R+ P + Q ++E
Sbjct: 511 KFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETL 570
Query: 1402 KKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLL--KEDTEKQKGKQAMPEKHESEM 1459
+ P K +L D +++ ++ + PL D+ Q + KH + +
Sbjct: 571 QATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSL 630
Query: 1460 SQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQR------RNLPSKIPLPTAMTS 1513
S ++ + ++ + LE P P ++S + +PS + P M S
Sbjct: 631 S--------IMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVS 682
Query: 1514 GSKS 1517
S
Sbjct: 683 SLTS 686
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 53.1 bits (126), Expect = 2e-06
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 15/144 (10%)
Query: 1195 GFCGAGG-----SSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSA 1249
G CG GG +SSR ++ + S SS S+ +S+ + + +SSS+SS +S+
Sbjct: 2593 GGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2652
Query: 1250 QAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQ------ 1303
++SS S++ +S S+T + + + A G A P + Q
Sbjct: 2653 SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARP 2712
Query: 1304 ----PPLPPPVPQPQEPQPERLSP 1323
P P PQPQ P P+ P
Sbjct: 2713 SAHSPGKKTPAPQPQAPPPQPTQP 2736
Score = 52.0 bits (123), Expect = 5e-06
Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 1/133 (0%)
Query: 1187 SCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSR 1246
+C SR A SSS S+ S S SS S+ +S+ + + +SSS+SS
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
Query: 1247 TSAQAASSQSANKTSPLVLDSNT-VTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPP 1305
+S+ ++SS S+ S+ TAG ++ A ++ Q P P
Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKK 2720
Query: 1306 LPPPVPQPQEPQP 1318
P P PQ PQP
Sbjct: 2721 TPAPQPQAPPPQP 2733
Score = 46.6 bits (109), Expect = 2e-04
Identities = 42/162 (25%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 1172 RRIVGISSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSAD 1231
R SS S S + SSS S+ S S SS S+ +S+
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSSSSSS 2656
Query: 1232 VENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQ 1291
+ + +SSS+SS T+ + +S S ++ +P + T A +K KQ+ ++
Sbjct: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP----APTAGPSAQAALPTKATKQAGK-AR 2711
Query: 1292 HHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPE 1333
AHSP ++ P P P PQP +P + + P E
Sbjct: 2712 PSAHSPGKKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKRE 2753
Score = 43.1 bits (100), Expect = 0.003
Identities = 88/407 (21%), Positives = 157/407 (38%), Gaps = 64/407 (15%)
Query: 1506 PLPTAMTSGSKSRNAQKTKGTSKLVDN------RPPALAKFL---PNSQELGNTSSSEGE 1556
P P + +K R+ + +K T + D P A A+ P+++ G+ +++ E
Sbjct: 2291 PSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATL-E 2349
Query: 1557 KDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPA-----AP 1611
+ +P E S P+ SST K + ++ + + +P SP+PPA AP
Sbjct: 2350 EGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAP 2409
Query: 1612 CPFV-----ARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFA----AV 1662
PF A + + + ++ PK K+ ++ K PG+ V
Sbjct: 2410 EPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGV 2469
Query: 1663 TAGYDKS----------PGGNGFAKVSS--NKTGFSSSLGISH--AP----VDSDGSDSS 1704
T+ K PG G+ + S + + + G S AP D D +
Sbjct: 2470 TSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEP 2529
Query: 1705 G---LWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFN-- 1759
G + NP SPD A + + + S S S + S+ E
Sbjct: 2530 GPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDK 2589
Query: 1760 -------------SGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSS 1806
S S SPA+ S S +SS S + +++S ++S S++ SS
Sbjct: 2590 NGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2649
Query: 1807 SIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLG 1853
S SS+ SS+ ++ +++ +S T+ + + ++PA G
Sbjct: 2650 SSSSSSSSSSSSSSSSSSSSSST----TDEDSSCSSDDEAAPAPTAG 2692
Score = 42.4 bits (98), Expect = 0.004
Identities = 48/219 (21%), Positives = 78/219 (35%), Gaps = 21/219 (9%)
Query: 1202 SSSRPSAGSHKQCGPSVHPHSSHSNRNSADVE-----NVRAKNSSSTSSRTSAQAASSQS 1256
SSS S+GS S S D +N S+ SSR ++ A+SS S
Sbjct: 2559 SSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSS 2618
Query: 1257 ANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQE- 1315
++ +S S++ + ++ S + S S + S
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSS 2678
Query: 1316 -PQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPP 1374
+ +PAP A P S++ + T + K SP + QP
Sbjct: 2679 CSSDDEAAPAPTAGP-----------SAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQ 2727
Query: 1375 SPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDEL 1413
+P P+ +PLQ K + K K+++G P EL
Sbjct: 2728 APPPQPT---QPLQPKAQAGAKSRPKKREGVHLPTTKEL 2763
Score = 36.2 bits (82), Expect = 0.31
Identities = 98/440 (22%), Positives = 162/440 (36%), Gaps = 57/440 (12%)
Query: 1374 PSP---LPKSKGKGKPLQRKVKPPKK-----QEEKEKKGKGKPQEDELKDSLADDDSSST 1425
PSP +P +K + + + K EE K +G+ ++ K A D ++T
Sbjct: 2291 PSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAK---AKGDRAAT 2347
Query: 1426 TTETSNPDTE----PLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVK 1481
E NP E PL E + K++ PE + K + P+
Sbjct: 2348 LEE-GNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAP------PQPSPAP 2400
Query: 1482 PSSLELPYTPPL-ESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKF 1540
P+ P P E + PL T + K + A+ + + RP A+
Sbjct: 2401 PAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAEL 2460
Query: 1541 LPNSQELGNTS-SSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTS 1599
L G TS S+ K++ D PG+ K SL +L +
Sbjct: 2461 LVKLDHEGVTSPKSKKAKEALLLRED------PGAGGWQEPK-SLLSLGS---------Y 2504
Query: 1600 PTPASPSPPAAPCPFVARGSYSSI----VNSSSSSDPKIK-----QPNGSKHKLTKAASL 1650
P A S P AP P G + + S +PK + +G++ + ++S
Sbjct: 2505 PPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSS 2564
Query: 1651 PGKNGNPTFAAV----TAGYDKSP-GGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDSSG 1705
G + + + ++ T G ++ G+G +SS S A S S SS
Sbjct: 2565 SGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSS 2624
Query: 1706 LWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYL 1765
S S+ SS + +S S+ +S + + S S S + +S + +E +S S
Sbjct: 2625 S-SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683
Query: 1766 WESPATDPSPSWPASSGSPT 1785
+PA PS A + PT
Sbjct: 2684 EAAPAPTAGPS--AQAALPT 2701
Score = 34.3 bits (77), Expect = 1.2
Identities = 54/213 (25%), Positives = 78/213 (36%), Gaps = 48/213 (22%)
Query: 1252 ASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHS------------PLE 1299
++ + + KTS D+ G TAG + GAK G + A + P +
Sbjct: 2299 SAKRRSRKTSK---DTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTD 2355
Query: 1300 QHPQPPL---PPPVPQPQEPQPE---RLSPAPLAHPSHPERASSARHSSEDSDITSLIEA 1353
+ P PL P P ++ PE + + AP A P+ P+ S TS
Sbjct: 2356 EVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQP------SPAPPAFTSC--- 2406
Query: 1354 MDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPL----QRKVKPPKKQEEKEKKGKGKPQ 1409
PA E F E P P + PL + KP K + +E KG +
Sbjct: 2407 ----------PAPEPFAELPA---PATSLAPAPLITMPATRPKPKKARAAEESGAKGPRR 2453
Query: 1410 EDELKDSLADDDSSSTTTETSNPDTEP-LLKED 1441
E + L D T+ S E LL+ED
Sbjct: 2454 PGEEAELLVKLDHEGVTSPKSKKAKEALLLRED 2486
Score = 33.1 bits (74), Expect = 2.6
Identities = 40/166 (24%), Positives = 57/166 (34%), Gaps = 18/166 (10%)
Query: 1302 PQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSAR--HSSEDSDITSLIEAMDKD-- 1357
P P L P P + P P A LA E+ AR ++ + EA D D
Sbjct: 1939 PGPSLAAPTPGARGPDPSSPDKAKLA----VEKGRKARKLRGPKEPGFEAGPEASDDDLW 1994
Query: 1358 --------FDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQ 1409
F H S A P+ KG PL + + ++ K+ + K K +
Sbjct: 1995 TRRRSERIFLHDASAAAPAPVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGK 2054
Query: 1410 EDELKDSLADDDSSSTTTETSNPDTEPL--LKEDTEKQKGKQAMPE 1453
E L + + +E P L K K KGK+ E
Sbjct: 2055 EAGPGAGLPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKE 2100
Score = 32.3 bits (72), Expect = 4.5
Identities = 56/272 (20%), Positives = 87/272 (31%), Gaps = 34/272 (12%)
Query: 1298 LEQHPQPPLP------PPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLI 1351
L Q P P L P P + + + + + S +SS+ SS T
Sbjct: 2525 LAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGE 2584
Query: 1352 EAMDKDFDHHDSPA---LEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKP 1408
E DK+ D + + SP S
Sbjct: 2585 EEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 1409 QEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKK 1468
S + SSS+++ +S+ + ED+ +A P +Q +K
Sbjct: 2645 SSSSSSSS-SSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKA 2703
Query: 1469 LLNIKKEIPTDVKP---SSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQK--- 1522
K P+ P + P PP + Q PL +G+KSR ++
Sbjct: 2704 TKQAGKARPSAHSPGKKTPAPQPQAPPPQPTQ--------PLQPKAQAGAKSRPKKREGV 2755
Query: 1523 ----TKGTSK-----LVDNRPPALAKFLPNSQ 1545
TK +K V+NR P +A FLP Q
Sbjct: 2756 HLPTTKELAKRQRLPSVENR-PKIAAFLPARQ 2786
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 52.4 bits (124), Expect = 4e-06
Identities = 75/361 (20%), Positives = 129/361 (35%), Gaps = 50/361 (13%)
Query: 1210 SHKQCGPSVHPHSSHSNRNSADVEN-VRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSN 1268
+ KQ S HS+ S+ +E+ ++ +S + S + + S SA ++P L
Sbjct: 401 NQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPE- 459
Query: 1269 TVTQGHTAGRKSKGAKQSQHGSQHHAHSPL-EQHPQPPLPPPVPQPQEPQPERLS----- 1322
V H++ +S+ S S + S + PL P P+P+ P +
Sbjct: 460 PVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWL 519
Query: 1323 ---PAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPK 1379
P A P P R E S A ++ P + ++ P +P P+
Sbjct: 520 TKVSQPAAPPEGPRSTEPPRRHPESKG--SSDSATSQEHSESKDPPPKSSSKAPRAP-PE 576
Query: 1380 SKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPL-L 1438
+ GK + K P +QE +++ G Q + + A S ++ P P
Sbjct: 577 APHPGK--RSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
Query: 1439 KEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQR 1498
++ T K K K VK K + E V PSS ++
Sbjct: 635 RDQTSKDKPK-------------VKTKGRPRAAASNEPKPAVPPSS------------EK 669
Query: 1499 RNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKD 1558
+ S +P P+ SG + V++R P +P ++ G S G +
Sbjct: 670 KKHKSSLPAPSKALSGPEPAKDN--------VEDRTPEHFALVPLTESQGPPHSGSGSRT 721
Query: 1559 S 1559
S
Sbjct: 722 S 722
Score = 49.7 bits (117), Expect = 3e-05
Identities = 112/539 (20%), Positives = 183/539 (33%), Gaps = 117/539 (21%)
Query: 1202 SSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTS 1261
SSS P + P HSS SA+ E+ +SSS S S+ + S ++ +
Sbjct: 446 SSSAPPSAPQSLPEPVASAHSS-----SAESESTSDSDSSSDSESESSSSDSEENEPLET 500
Query: 1262 PL-----------VLD-----------------SNTVTQGHTAGRKSKGAKQSQHGSQHH 1293
P LD S + H + S + SQ S+
Sbjct: 501 PAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESK 560
Query: 1294 AHSPLEQHPQPPLPPPVP---------QPQEPQPERLSPAPLAHPSHPERASS---ARHS 1341
P P PP P P + +P + P P +AS+ +R S
Sbjct: 561 DPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTS 620
Query: 1342 SEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKE 1401
+ L+ +D D P ++ P++ +P + PP +++K
Sbjct: 621 LQGEREPGLLPYGSRDQTSKDKPKVKT------KGRPRAAASNEP--KPAVPPSSEKKKH 672
Query: 1402 KK---------GKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMP 1452
K +P +D ++D + + TE+ P P + +QA+
Sbjct: 673 KSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGP---PHSGSGSRTSGCRQAVV 729
Query: 1453 EKHESEMSQ--VKQKSKKLLNIKKEIPTDVKPSSLELPYT---------PPLESKQRRNL 1501
+ +S + + + KLL+ ++ P P SL + T PP + ++R
Sbjct: 730 VQEDSRKDRLPLPLRDTKLLSPLRDTP---PPQSLMVKITLDLLSRIPQPPGKGSRQRKA 786
Query: 1502 PSKIP------LPTAMTSGSKSRNAQKTKGTSKL-VDNRPPALAKFLPNSQELGNTSSSE 1554
K P +S S S+ A+K KG ++ DN+ L K + + ++S E
Sbjct: 787 EDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKE 846
Query: 1555 GEKDSP-------------PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPT 1601
K P PP S KP + T D + S T
Sbjct: 847 SSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQD---PPKSASST 903
Query: 1602 PASPSPPAAPCP--FVARGSYSSIVNSSSSSD-----PKIKQPNGSKHKLTKAASLPGK 1653
++ + P +GS SS + SS D P PNG+ S PGK
Sbjct: 904 KSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGN--------SKPGK 954
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 52.4 bits (124), Expect = 4e-06
Identities = 114/568 (20%), Positives = 202/568 (35%), Gaps = 73/568 (12%)
Query: 1178 SSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRA 1237
SSE + CD R GS+S PS + + S SSHS S+ + +
Sbjct: 388 SSEDSDGEQDCDKTMPRS---TPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSES 444
Query: 1238 KNSSSTS-SRTSAQAASSQ------------------SANKTSPL-VLDSNTVTQGHTAG 1277
++SSS S + +Q+AS + + +K SP +DSN + + G
Sbjct: 445 ESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPS---SQG 501
Query: 1278 RKSKGAKQSQHGSQHHAHSPLE-QHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERAS 1336
K +G +Q S P E P Q +P S +R +
Sbjct: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
Query: 1337 SARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPS-PLPKSKGKGKP-LQRKVKPP 1394
+ + ++ + E ++P +++ + P S +KG KP ++++ K
Sbjct: 562 VGKKQPKKAEKAAAEEPRGGLKIESETP-VDLASSMPSSRHKAATKGSRKPNIKKESKSS 620
Query: 1395 KKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEK 1454
+ ++KK K + + + + D+SS+ ++ S + P
Sbjct: 621 PRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS 680
Query: 1455 HESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSG 1514
E E S +Q+ + +KE+ + + P ++ +P K T G
Sbjct: 681 VEEEDSFFRQRMFSPME-EKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
Query: 1515 SKSRNAQK-TKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPG 1573
K +K T+ K + K +++ S S+ P E + HKP
Sbjct: 740 EKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESK----KPKTEDKNSAGHKPS 795
Query: 1574 SSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPK 1633
S+ +S + K++ P+PA P P S DPK
Sbjct: 796 SNRES---------SKQSAAKEKDLLPSPAGPVP---------------------SKDPK 825
Query: 1634 IKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISH 1693
+ K +++++SL + + T+G K+ K + KT SS
Sbjct: 826 TEH-GSRKRTISQSSSLKSSSNS---NKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEK 881
Query: 1694 APVDSDGSDSSGLWSPVSNPSSPDFTPL 1721
AP S S +P + S P T L
Sbjct: 882 APSSSSNCPPS---APTLDSSKPRRTKL 906
Score = 43.5 bits (101), Expect = 0.002
Identities = 106/529 (20%), Positives = 181/529 (34%), Gaps = 115/529 (21%)
Query: 1178 SSEGNLNTLSCDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRA 1237
+S+ + GHS AG SS S+G H S+
Sbjct: 117 TSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQR-------HDRESY------------- 156
Query: 1238 KNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQ-HGSQHHAHS 1296
N+S +SSR Q S S +++S + G S + S+ HG+ HH+
Sbjct: 157 -NNSGSSSRKKGQHGSEHSKSRSS---------SPGKPQAVSSLNSSHSRSHGNDHHS-- 204
Query: 1297 PLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDK 1356
++H + P++P SP+ + SS +HS++
Sbjct: 205 --KEHQRS------KSPRDPDANWDSPSRVPF-------SSGQHSTQSF----------- 238
Query: 1357 DFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDS 1416
PPS + KS + V+P QE E K
Sbjct: 239 ----------------PPSLMSKSNSMLQKPTAYVRPMDGQESMEPK------------- 269
Query: 1417 LADDDSSSTTTETSNPDTEPLLKEDTEKQK-GKQAMPEKHESEMSQVKQKSKKLLNIKKE 1475
L+ + SS + S + +P K K K Q + ++S V + K++
Sbjct: 270 LSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEM------ 323
Query: 1476 IPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSK-SRNAQKTKGTSKLVDNRP 1534
T P L +TP + PSK P PT + S QK SK +
Sbjct: 324 --THSWPPPLTAIHTP------CKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQ 375
Query: 1535 PALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLK 1594
L + +L ++ S+GE+D ++P PGS+++ + S N+
Sbjct: 376 S--KSMLKDDLKLSSSEDSDGEQDCD----KTMPRSTPGSNSEPSHHNSEGADNS----- 424
Query: 1595 QRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKN 1654
+ +S S S + + S S S S+ P+ + P +K +L + +
Sbjct: 425 RDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPH 484
Query: 1655 GNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPVDSDGSDS 1703
++V + S G + ++ + G + G DS
Sbjct: 485 KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDS 533
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 52.4 bits (124), Expect = 4e-06
Identities = 71/318 (22%), Positives = 113/318 (35%), Gaps = 47/318 (14%)
Query: 1305 PLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSP 1364
P P P+P+P+EP PE+ S R S S S S + + H S
Sbjct: 248 PKPEPIPEPKEPSPEKNSKK--EKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305
Query: 1365 ALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSS 1424
+ + PSP + + + R++ PP + + + + SL+ SSS
Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA---SLSGSSSSS 362
Query: 1425 TTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSS 1484
+++ + +P +P + + +K ++ P S + P P +
Sbjct: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSP-----------SASPPRRRHRPSPPATPPPKT 411
Query: 1485 LELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNS 1544
P TP ++ R++ S P G S K KGT K P P
Sbjct: 412 RHSP-TPQQSNRTRKSRVSVSP-------GRTSGKVTKHKGTEKRESPSPAP----KPRK 459
Query: 1545 QELGNTSSSEGEKDSPPPEWDSVPVHK---------------PGSSTDSLYKLSLQTLNA 1589
EL S SE +K DSV + SS D K S N
Sbjct: 460 VEL---SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS-HVKNG 515
Query: 1590 DIFLKQRQTSPTPASPSP 1607
++ ++R + ASPSP
Sbjct: 516 EVGRRRRHSPSRSASPSP 533
Score = 46.6 bits (109), Expect = 2e-04
Identities = 76/361 (21%), Positives = 119/361 (32%), Gaps = 61/361 (16%)
Query: 1222 SSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKT-SPLVLDSNTVTQGHTAGRKS 1280
SS + +S+ E+ R K S + + S S + + SP T +G R+
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR---RRR 548
Query: 1281 KGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARH 1340
+ + + +P + + P PPP + P P R SP+P + +R S
Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS--- 605
Query: 1341 SSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKV--KPPKKQE 1398
SP + T PP P + P +R+V PP KQ
Sbjct: 606 ---------------------PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQR 644
Query: 1399 EKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESE 1458
+ P SS + S+P T + + Q S
Sbjct: 645 SSPVTKRRSP------------SLSSKHRKGSSP------SRSTREARSPQPNKRHSPSP 686
Query: 1459 MSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSR 1518
+ Q S +++ + + P T P+ R P KI + S S
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI-----KKAASPSP 741
Query: 1519 NAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWD-SVPVHKPGSSTD 1577
+ + +S+ V P AK P S + SP W +VPV K S T
Sbjct: 742 QSVRRVSSSRSVSGSPEPAAKKPP-------APPSPVQSQSPSTNWSPAVPVKKAKSPTP 794
Query: 1578 S 1578
S
Sbjct: 795 S 795
Score = 44.7 bits (104), Expect = 9e-04
Identities = 71/346 (20%), Positives = 117/346 (33%), Gaps = 48/346 (13%)
Query: 1333 ERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQR--- 1389
E+ +S + ED D E S + + PSP +S + +R
Sbjct: 139 EKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS 198
Query: 1390 -------KVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDT 1442
K + P EK++K P+ + +++ST+ P EP + E
Sbjct: 199 RSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP-IPEPK 257
Query: 1443 EKQKGKQAMPEKH-ESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNL 1501
E K + EK E + + +SK + P+ +P S+ R
Sbjct: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH-------RSRSRSYS 310
Query: 1502 PSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPP 1561
P + P P S + ++ + +R P + ++ G++SSS + P
Sbjct: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370
Query: 1562 PEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPA------SPSPPAAPCPFV 1615
P+ KP T S + K R+ SP+ + PSPPA P P
Sbjct: 371 PK-------KPPKRTSSPPR------------KTRRLSPSASPPRRRHRPSPPATPPPKT 411
Query: 1616 ARGSYSSIVNSSSSSDPKIKQPNGS----KHKLTKAASLPGKNGNP 1657
N + S + S KHK T+ P P
Sbjct: 412 RHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
Score = 36.6 bits (83), Expect = 0.24
Identities = 110/571 (19%), Positives = 174/571 (30%), Gaps = 159/571 (27%)
Query: 1179 SEGNLNTLSCDPGH----------SRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRN 1228
S+ T S P H SR + S R ++ P P R+
Sbjct: 282 SKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS 341
Query: 1229 SADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQH 1288
+ V R ++S + S +S+ ++ S+S K P S RK++ S
Sbjct: 342 RSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPP--------RKTRRLSPS-- 391
Query: 1289 GSQHHAHSPLEQH-PQPPLPPPVPQPQEPQPERLSPAPLAHPS-HPERASS--ARHSSED 1344
A P +H P PP PP P P++ + + S P R S +H +
Sbjct: 392 -----ASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTE 446
Query: 1345 SDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKG 1404
+ PSP PK RKV+ + +E+K K
Sbjct: 447 K-------------------------RESPSPAPKP--------RKVELSESEEDKGGKM 473
Query: 1405 KG------KPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESE 1458
+ Q + D SS+++E P + ++ E + ++ P + S
Sbjct: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV--KNGEVGRRRRHSPSRSASP 531
Query: 1459 MSQVKQKSKKLLNIKKEIP---------------------TDVKPSSLELPYTPPLESK- 1496
+ +QK ++ P T P P PP
Sbjct: 532 SPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSP 591
Query: 1497 ---------QRRNLPSKIPLP-TAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQE 1546
QRR PS P TA R A + + V + PP + P ++
Sbjct: 592 SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKR 651
Query: 1547 LGNTSSSEGEKDSPP------------------------PEWDSVPV------------- 1569
+ SS+ K S P P+ S P
Sbjct: 652 RSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRR 711
Query: 1570 HKPGSSTDSLYKLSL---------------QTLNADIFLKQRQTSPTPASPSPPAAPCPF 1614
P ST + ++S Q++ + SP PA+ PPA P P
Sbjct: 712 QSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPV 771
Query: 1615 VARG-----SYSSIVNSSSSSDPKIKQPNGS 1640
++ S + V + S P P S
Sbjct: 772 QSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802
Score = 36.2 bits (82), Expect = 0.31
Identities = 59/303 (19%), Positives = 104/303 (34%), Gaps = 63/303 (20%)
Query: 1149 PFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAGGSSSRPSA 1208
P +RR+S S PP P RR +SS+ H +G + + S
Sbjct: 630 PPKRRVSH--SPPPKQRSSPVTKRRSPSLSSK-----------HRKGSSPSRSTREARSP 676
Query: 1209 GSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSN 1268
+K+ PS P + ++ + V + +SS+ R + + S++ + S
Sbjct: 677 QPNKRHSPSPRPRAPQTSSSPPPVR----RGASSSPQRRQSPSPSTRPIRRVSRTPEPKK 732
Query: 1269 TVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAH 1328
A S + + S+ + SP +PP PP Q Q P P+
Sbjct: 733 I----KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKK 788
Query: 1329 PSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQ 1388
P + S +S+ +G GK +
Sbjct: 789 AKSPTPSPSPPRNSD------------------------------------QEGGGKKKK 812
Query: 1389 RKVKPPKKQEEKEKKGKGKPQEDELKDSLADD------DSSSTTTETSNPDTEPLLKEDT 1442
+K K+++K KK K +E + + A +++TT P P K++T
Sbjct: 813 KKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKET 872
Query: 1443 EKQ 1445
E +
Sbjct: 873 ESE 875
Score = 33.5 bits (75), Expect = 2.0
Identities = 50/254 (19%), Positives = 90/254 (35%), Gaps = 40/254 (15%)
Query: 1253 SSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPL-PPPVP 1311
SS + SP + S+ +G + R ++ A+ Q ++ H+ SP + PQ PPPV
Sbjct: 645 SSPVTKRRSPSL--SSKHRKGSSPSRSTREARSPQP-NKRHSPSPRPRAPQTSSSPPPVR 701
Query: 1312 QPQEPQPERL-SPAPLAHP-------SHPERASSARHSSEDSDITSLIEAMDKDFDHHDS 1363
+ P+R SP+P P P++ A S S + + S
Sbjct: 702 RGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS-----VRRVSSSRSVSGS 756
Query: 1364 PALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSS 1423
P E ++PP+P + + P K+ + P+
Sbjct: 757 P--EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR-------------- 800
Query: 1424 STTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPS 1483
N D E K+ +K+ K +KH+ K+K+ P + +
Sbjct: 801 -------NSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAA 853
Query: 1484 SLELPYTPPLESKQ 1497
+ L P+ + +
Sbjct: 854 TTTLAQEEPVAAPE 867
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 51.6 bits (122), Expect = 7e-06
Identities = 117/637 (18%), Positives = 228/637 (35%), Gaps = 69/637 (10%)
Query: 1236 RAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSK--GAKQSQHGSQHH 1293
R N ++T S ++AN+ + T + TA + A+ ++HG +
Sbjct: 310 RTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGER-- 367
Query: 1294 AHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPER--------ASSARHSSEDS 1345
++ P P + E +P+P H ER SS+ S+E
Sbjct: 368 ---TANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHG 424
Query: 1346 DITSLIE-----AMDKDFDHHDSPALEVFTEQPPSPLP--KSKGKGKPLQRKVKPPKKQE 1398
+ T L + + ++ + A E T P P ++ K V+P + +E
Sbjct: 425 ERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRE 484
Query: 1399 ----EKEKKGKGKPQEDELKDSLADDDSSSTTTE-TSNPDTEPLLKEDTEKQKGKQAMPE 1453
EK +P E+ + A++ ++S++ E T + + PL E+T P
Sbjct: 485 TTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENT--------TPS 536
Query: 1454 KHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTS 1513
E ++ + ++K E + + L T P ++ N + P T+
Sbjct: 537 PAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTEN-GQRTPFANEKTT 595
Query: 1514 GSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPG 1573
S + + + T +N P+ A+ N + N E +P P +
Sbjct: 596 SSSAEPTEHEERTPLANENTTPSPAEPTENRERTAN------ENTTPSPAGPTENREMTA 649
Query: 1574 SSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPK 1633
+ +L+ T N + ++ TS +PA P+ PF + SS S+ ++
Sbjct: 650 NEKTTLFPAE-PTENRERTANEKTTS-SPAEPTENGQRTPFANEKTTSS---SAEPTEHG 704
Query: 1634 IKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISH 1693
+ P +++ T + + P +N T T + P N + N T +
Sbjct: 705 ERTPLANEN-TTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQ----- 758
Query: 1694 APVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQR 1753
++ D + L + + PS + T + F N + R+ +
Sbjct: 759 ---PTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERT--PLANE 813
Query: 1754 SWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNL 1813
+ + P+ E A + + +PA PT S + + P + W++N
Sbjct: 814 NTTSSPAEPTENRERTANEKTTQFPA---EPTENRESTANEKTTPFPAEPTENREWTANE 870
Query: 1814 SSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPAD 1850
++ L P E +P + +T SPA+
Sbjct: 871 NTTLSPAEPTE--------HEEMTPLANEKTTLSPAE 899
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 51.2 bits (121), Expect = 9e-06
Identities = 83/446 (18%), Positives = 142/446 (31%), Gaps = 41/446 (9%)
Query: 1216 PSVHPHSSHSNRNSADVEN---VRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQ 1272
PS+ P+S S S V V K +++T+ +TS ++ K + + ++
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 1273 GHTAGRKSKGAKQSQHGSQHHA-HSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLA--HP 1329
T+ +K +++ ++ A +P E P P P P+EP P + AP P
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 1330 SHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQR 1389
+ S+ E + T+ E P P P + + P
Sbjct: 248 APTTTKSAPTTPKEPAPTTT----------------KEPAPTTPKEPAPTTTKEPAPTTT 291
Query: 1390 KVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQ 1449
K P +E K KP K+ T T P T ++
Sbjct: 292 KSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 350
Query: 1450 AMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPT 1509
P+K + K K+ PT K S P P + + +K P PT
Sbjct: 351 TAPKK----PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 1510 AMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNS--------------QELGNTSSSEG 1555
S + T + P A P +E T++ +
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 466
Query: 1556 EKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFV 1615
+P + P ++ L + + L K T+P +P+ P P P
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 526
Query: 1616 ARGSYSSIVNSSSSSDPKIKQPNGSK 1641
+ +++ + PK P K
Sbjct: 527 PEEPAPTTPKAAAPNTPKEPAPTTPK 552
Score = 49.7 bits (117), Expect = 3e-05
Identities = 75/357 (21%), Positives = 117/357 (32%), Gaps = 40/357 (11%)
Query: 1296 SPLEQHPQPPLPPPVPQPQEPQP---ERLSPAPLAHPSHPERASSARHSSEDSDITSLIE 1352
+P + P P P P+EP P + SP P+ P SA ++++ T+
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKS 410
Query: 1353 AMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDE 1412
A + + E P P P + K P K P +E KP
Sbjct: 411 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT 470
Query: 1413 LKDSL--ADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLL 1470
K+ +++ TT + P T L T +K PE E++ +
Sbjct: 471 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP-EKPAPTTPE----ELAPTTPEEPTPT 525
Query: 1471 NIKKEIPTDVKPSSLELPYTP-PLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKL 1529
++ PT K ++ P P P K+ K P PT K KGT+
Sbjct: 526 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPT 581
Query: 1530 VDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNA 1589
P P +EL T++ E S KP +T
Sbjct: 582 TLKEPAPTTPKKPAPKELAPTTTKEPT---------STTCDKPAPTTPK----------- 621
Query: 1590 DIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTK 1646
T+P +P+ P P P +G+ + + + + PK P TK
Sbjct: 622 ----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 674
Score = 41.6 bits (96), Expect = 0.007
Identities = 82/401 (20%), Positives = 121/401 (30%), Gaps = 70/401 (17%)
Query: 1296 SPLEQHPQPPLPPPVPQPQEPQPERLSPAPLA---------------------------- 1327
+P E P P P P+EP P PAP
Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 372
Query: 1328 ------HPS-------HPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPP 1374
PS P SA ++++ T+ A + + E P
Sbjct: 373 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432
Query: 1375 SPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDT 1434
P P + K P K P +E KP K+ + TT T
Sbjct: 433 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-------PAPTTPKETAPT 485
Query: 1435 EPLLKEDTEKQKGKQAMPEK----HESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYT 1490
P T +K PEK E++ + ++ PT K ++ P
Sbjct: 486 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545
Query: 1491 P-PLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGN 1549
P P K+ K P PT K KGT+ P P +EL
Sbjct: 546 PAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601
Query: 1550 TSSSEG-----EKDSPPPEWDSVPV--HKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTP 1602
T++ E +K +P + P +P +T + A LK+ P P
Sbjct: 602 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAP 657
Query: 1603 ASPSPPAAP--CPFVARGSYSSIVNSSSSSDPKIKQPNGSK 1641
+P PA P +G S+ + + + PK P K
Sbjct: 658 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 698
Score = 36.6 bits (83), Expect = 0.24
Identities = 65/320 (20%), Positives = 105/320 (32%), Gaps = 41/320 (12%)
Query: 1390 KVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETS------------------- 1430
+VK KK K+K P DE L + D TT +TS
Sbjct: 65 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 124
Query: 1431 --------NPDTE-----PLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIP 1477
N DT + KE T + K ++ ++ + +K+ +I+K
Sbjct: 125 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 184
Query: 1478 TDVKPSSLELPY-TPPLE--SKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRP 1534
D+ P+S L TP E +K K P PT + + + T T K P
Sbjct: 185 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 244
Query: 1535 ----PALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNAD 1590
P K P + + ++++ + P E +P +T + +
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304
Query: 1591 IFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASL 1650
K T+P +P+ P P P + + + + PK P K
Sbjct: 305 TPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 363
Query: 1651 PGKNGNPTFAAVTAGYDKSP 1670
P P A T + SP
Sbjct: 364 PAPT-TPKEPAPTTTKEPSP 382
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 51.2 bits (121), Expect = 9e-06
Identities = 83/446 (18%), Positives = 142/446 (31%), Gaps = 41/446 (9%)
Query: 1216 PSVHPHSSHSNRNSADVEN---VRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQ 1272
PS+ P+S S S V V K +++T+ +TS ++ K + + ++
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 1273 GHTAGRKSKGAKQSQHGSQHHA-HSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLA--HP 1329
T+ +K +++ ++ A +P E P P P P+EP P + AP P
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 1330 SHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQR 1389
+ S+ E + T+ E P P P + + P
Sbjct: 289 APTTTKSAPTTPKEPAPTTT----------------KEPAPTTPKEPAPTTTKEPAPTTT 332
Query: 1390 KVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQ 1449
K P +E K KP K+ T T P T ++
Sbjct: 333 KSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 391
Query: 1450 AMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPT 1509
P+K + K K+ PT K S P P + + +K P PT
Sbjct: 392 TAPKK----PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 1510 AMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNS--------------QELGNTSSSEG 1555
S + T + P A P +E T++ +
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 507
Query: 1556 EKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFV 1615
+P + P ++ L + + L K T+P +P+ P P P
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 567
Query: 1616 ARGSYSSIVNSSSSSDPKIKQPNGSK 1641
+ +++ + PK P K
Sbjct: 568 PEEPAPTTPKAAAPNTPKEPAPTTPK 593
Score = 49.7 bits (117), Expect = 3e-05
Identities = 75/357 (21%), Positives = 117/357 (32%), Gaps = 40/357 (11%)
Query: 1296 SPLEQHPQPPLPPPVPQPQEPQP---ERLSPAPLAHPSHPERASSARHSSEDSDITSLIE 1352
+P + P P P P+EP P + SP P+ P SA ++++ T+
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKS 451
Query: 1353 AMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDE 1412
A + + E P P P + K P K P +E KP
Sbjct: 452 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT 511
Query: 1413 LKDSL--ADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLL 1470
K+ +++ TT + P T L T +K PE E++ +
Sbjct: 512 PKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP-EKPAPTTPE----ELAPTTPEEPTPT 566
Query: 1471 NIKKEIPTDVKPSSLELPYTP-PLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKL 1529
++ PT K ++ P P P K+ K P PT K KGT+
Sbjct: 567 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPT 622
Query: 1530 VDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNA 1589
P P +EL T++ E S KP +T
Sbjct: 623 TLKEPAPTTPKKPAPKELAPTTTKEPT---------STTCDKPAPTTPK----------- 662
Query: 1590 DIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTK 1646
T+P +P+ P P P +G+ + + + + PK P TK
Sbjct: 663 ----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 715
Score = 41.6 bits (96), Expect = 0.007
Identities = 82/401 (20%), Positives = 121/401 (30%), Gaps = 70/401 (17%)
Query: 1296 SPLEQHPQPPLPPPVPQPQEPQPERLSPAPLA---------------------------- 1327
+P E P P P P+EP P PAP
Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 413
Query: 1328 ------HPS-------HPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPP 1374
PS P SA ++++ T+ A + + E P
Sbjct: 414 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473
Query: 1375 SPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDT 1434
P P + K P K P +E KP K+ + TT T
Sbjct: 474 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-------PAPTTPKETAPT 526
Query: 1435 EPLLKEDTEKQKGKQAMPEK----HESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYT 1490
P T +K PEK E++ + ++ PT K ++ P
Sbjct: 527 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586
Query: 1491 P-PLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGN 1549
P P K+ K P PT K KGT+ P P +EL
Sbjct: 587 PAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642
Query: 1550 TSSSEG-----EKDSPPPEWDSVPV--HKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTP 1602
T++ E +K +P + P +P +T + A LK+ P P
Sbjct: 643 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAP 698
Query: 1603 ASPSPPAAP--CPFVARGSYSSIVNSSSSSDPKIKQPNGSK 1641
+P PA P +G S+ + + + PK P K
Sbjct: 699 TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 739
Score = 36.6 bits (83), Expect = 0.24
Identities = 65/320 (20%), Positives = 105/320 (32%), Gaps = 41/320 (12%)
Query: 1390 KVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETS------------------- 1430
+VK KK K+K P DE L + D TT +TS
Sbjct: 106 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 165
Query: 1431 --------NPDTE-----PLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIP 1477
N DT + KE T + K ++ ++ + +K+ +I+K
Sbjct: 166 NPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA 225
Query: 1478 TDVKPSSLELPY-TPPLE--SKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRP 1534
D+ P+S L TP E +K K P PT + + + T T K P
Sbjct: 226 KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 285
Query: 1535 ----PALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNAD 1590
P K P + + ++++ + P E +P +T + +
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345
Query: 1591 IFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASL 1650
K T+P +P+ P P P + + + + PK P K
Sbjct: 346 TPKKPAPTTPKEPAPTTPKEPTPTTPK-EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 404
Query: 1651 PGKNGNPTFAAVTAGYDKSP 1670
P P A T + SP
Sbjct: 405 PAPT-TPKEPAPTTTKEPSP 423
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 50.8 bits (120), Expect = 1e-05
Identities = 75/324 (23%), Positives = 104/324 (32%), Gaps = 61/324 (18%)
Query: 1307 PPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPAL 1366
PPP P E QP + PA +A S P A A+ + S I DF +
Sbjct: 871 PPPTPPAMESQPLKPVPANVAPQSPP--AVKAKPKWQPSSIP----VPSPDFPPPPPESS 924
Query: 1367 EVFTEQPPSPLPKSKGKGKPL-----QRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDD 1421
VF PPSP+P P + P KK + G KP ++S
Sbjct: 925 LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSS 984
Query: 1422 SSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVK 1481
S + E P + L+ + T + P K
Sbjct: 985 SGAEHPEPKRPSVDSLVSKFTPP--AESGSPSKE-------------------------- 1016
Query: 1482 PSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSK---LVDNRPPALA 1538
+L P PP K NL S + LP + G S A G K + PP+ +
Sbjct: 1017 --TLPPPAAPPKPGKL--NL-SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDS 1071
Query: 1539 KFLPNSQEL--------------GNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSL 1584
F P E GNTS + P +W + V K T S
Sbjct: 1072 DFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDST 1131
Query: 1585 QTLNADIFLKQRQTSPTPASPSPP 1608
+ A+I + + P P+ P
Sbjct: 1132 RLTQAEISEQPTMATVVPQVPTSP 1155
Score = 50.1 bits (118), Expect = 2e-05
Identities = 73/308 (23%), Positives = 107/308 (34%), Gaps = 42/308 (13%)
Query: 1302 PQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHH 1361
P PP PPP+P P PQ P PL P + + + +
Sbjct: 761 PTPPPPPPIPAPLPPQ---APPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQP 817
Query: 1362 DSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDD 1421
PA + P P+P V PP +++ K P S+
Sbjct: 818 AFPASYIPPSPPTPPVP------------VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI 865
Query: 1422 SSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVK 1481
+S + P T P ++ K P+ + ++ K + + + P
Sbjct: 866 AS----QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP 921
Query: 1482 PSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRN-AQKTKGTSKLVDNRPPALAKF 1540
SSL P PP P P PTA + KS + +KT TS +PP
Sbjct: 922 ESSLVFPPPPPSPVP----APPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP----- 972
Query: 1541 LPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSP 1600
P Q + SS G + P P+ SV DSL +S T A+ ++T P
Sbjct: 973 -PTPQRNSSIKSSSG-AEHPEPKRPSV---------DSL--VSKFTPPAESGSPSKETLP 1019
Query: 1601 TPASPSPP 1608
PA+P P
Sbjct: 1020 PPAAPPKP 1027
Score = 43.1 bits (100), Expect = 0.003
Identities = 120/567 (21%), Positives = 179/567 (31%), Gaps = 82/567 (14%)
Query: 1217 SVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTA 1276
S+ S S +S+ + ++ +S+ + S S + +++ + S +G
Sbjct: 528 SLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQL 587
Query: 1277 GRKSKGAKQSQHGSQHHAHSPLEQHPQ-----------PPLPPPVPQ-PQEPQPERLSPA 1324
SK +S + PL P+ PPLPPP P P P P P
Sbjct: 588 EESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPP 647
Query: 1325 PLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQ------------ 1372
PL S P S+A + S IT L A P V Q
Sbjct: 648 PLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNG 707
Query: 1373 ---PPSPLPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTET 1429
PP P P G + + P + P + + + T
Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHIT--QVAPPTPPP 765
Query: 1430 SNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPY 1489
P PL + K P ++ V Q + +P K + Y
Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP--TPTPPVPPAKKQPAFPASY 823
Query: 1490 TPPLESKQRRNLPSKIPLPTAMTSGS------KSRNAQKTKGTSKLVDNRPPALAKFLPN 1543
PP P +P PT S S + ++ PP
Sbjct: 824 IPPSPPTP----PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879
Query: 1544 SQELGNTSSSEGEKDSP----PPEW--DSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQ 1597
SQ L ++ + P P+W S+PV P + +
Sbjct: 880 SQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSP--------DFPPPPPESSLVFPPPP 931
Query: 1598 TSPTPASPSPP---AAPCP--FVARGSYSSIVNSSSSSDP--------KIKQPNGSKHKL 1644
SP PA P PP A+P P + G +S +S P IK +G++H
Sbjct: 932 PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991
Query: 1645 TKAASL---------PGKNGNPTFAAVTAGYDKSPGGNGFAKVSS-NKTGFSSSLGIS-H 1693
K S+ P ++G+P + T +P G +S N G +S
Sbjct: 992 PKRPSVDSLVSKFTPPAESGSP--SKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049
Query: 1694 APVDSDGSDSSGLWSPVSNPSSPDFTP 1720
APV S S + P S PS DF P
Sbjct: 1050 APVLSGRGKDSVVEFP-SPPSDSDFPP 1075
Score = 32.7 bits (73), Expect = 3.4
Identities = 72/320 (22%), Positives = 108/320 (33%), Gaps = 74/320 (23%)
Query: 1304 PPLPPPVPQPQEPQPERLSPAP------------------LAHPSHPERASSARHSS--- 1342
PP P PVP P P P SP P P P+R SS + SS
Sbjct: 929 PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAE 988
Query: 1343 ----EDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGKGKPLQRKVKPPKKQE 1398
+ + SL+ + SP+ E T PP+ PK GK V P +
Sbjct: 989 HPEPKRPSVDSLVSKFTPPAE-SGSPSKE--TLPPPAAPPK---PGKLNLSGVNLPGVLQ 1042
Query: 1399 E-------KEKKGKGKPQEDELKDSLADDDSSSTTTETSNP------------DTEPLL- 1438
+ G+GK E +D D ET P +T P +
Sbjct: 1043 QGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVA 1102
Query: 1439 -----KEDTEKQKGKQAMP-----EKHESEMSQVK-QKSKKLLNIKKEIPTDVKPSSLEL 1487
+ K K+A P + ++Q + + + + ++PT K S L
Sbjct: 1103 VVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSS---L 1159
Query: 1488 PYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNR-PPALAKFLPNSQE 1546
P + R L K + GS S + + T+ + D PP + L + Q+
Sbjct: 1160 SVQPGFLADLNRTLQRK----SITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQK 1215
Query: 1547 LG----NTSSSEGEKDSPPP 1562
G + S + PPP
Sbjct: 1216 AGYGGSHISGYATLRRGPPP 1235
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 50.8 bits (120), Expect = 1e-05
Identities = 140/644 (21%), Positives = 231/644 (35%), Gaps = 108/644 (16%)
Query: 1226 NRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQ 1285
N S+D + SSS SS T A A+ S+++ + + S + T+G + K G
Sbjct: 112 NSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNA--ITSSYSSTRGISQLWKRNGPSS 169
Query: 1286 SQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDS 1345
S SP Q P E +++ L H S +A S+
Sbjct: 170 SPFS------SPASSRSQTP---------ERPAKKIREEELCHHSSSSTPLAADRESQGE 214
Query: 1346 DITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKSKGK----GKPLQRKVKPPKKQEEKE 1401
++ + +P ++ LP +G+ P Q + + E
Sbjct: 215 KAADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLE 274
Query: 1402 KKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQ 1461
KK + L+D D +S++ TET P T+P
Sbjct: 275 KKASLQWFNQALEDK--SDAASNSVTETP-PITQPSF----------------------- 308
Query: 1462 VKQKSKKLLNIKKEIPTDVKPSSLELPYTPP-LESKQRRNLPSKIPLPTAMTSGSKSRNA 1520
+ P P+SL P T P LES ++ P +P P ++G+ + A
Sbjct: 309 -------TFTLPAAAPAS-PPTSLLAPSTNPLLESLKKMQTPPSLP-PCPESAGAATTEA 359
Query: 1521 QKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLY 1580
T L+ PP L S G S + P +P +TD+
Sbjct: 360 LSPPKTPSLL---PPL---GLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDT-- 411
Query: 1581 KLSLQTLNADIFLKQRQTS-PTPA------------SPSPPAAPCPFVARGSYSSIVNSS 1627
+ TL A+ K + TS P+PA SPS PAAP A + I +
Sbjct: 412 -KAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAP 470
Query: 1628 SSSDPKIKQPNGSKHKLT--KAASLPGKNGN--PTFAAVTAGYDKSPGGNGFAKVSSNKT 1683
S+ + P G T ++SLP PTF V + P +T
Sbjct: 471 PKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG-PPASVPLPAPFFKQT 529
Query: 1684 GFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGL 1743
++ + AP+ + + ++ +P+++ S T S AFG N S +
Sbjct: 530 TTPATAPTTTAPLFTGLASATSAVAPITSASPS--TDSASKPAFGFGINSV----SSSSV 583
Query: 1744 SRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTP 1803
S + + A+ S P +P A+S +P + G L +TT
Sbjct: 584 STTTSTATAAS-------------QPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
Query: 1804 FSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSS 1847
++ +S +L +A+P T + ++ G ++ A AP+TSS
Sbjct: 631 VTT--FSQSLHTAVPTATSS---SAADFSGFGSTLATSAPATSS 669
Score = 46.6 bits (109), Expect = 2e-04
Identities = 140/675 (20%), Positives = 218/675 (32%), Gaps = 111/675 (16%)
Query: 1190 PGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAK---------NS 1240
P SR + SS+R + K+ GPS P SS ++ S E K +S
Sbjct: 141 PSSSRNAITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSS 200
Query: 1241 SSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQ 1300
SST ++ ++A+ T +SN+ + ++G++ + + P +
Sbjct: 201 SSTPLAADRESQGEKAADTTPRKKQNSNSQSTPGSSGQRKRKVQLL----------PSRR 250
Query: 1301 HPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDH 1360
Q LPPP P+ S D + + ++ ++ +
Sbjct: 251 GEQLTLPPP----------------------PQLGYSITAEDLDLEKKASLQWFNQALED 288
Query: 1361 HDSPALEVFTEQPPSP-------LPKSKGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDEL 1413
A TE PP LP + P E KK + P
Sbjct: 289 KSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPC 348
Query: 1414 KDSLADDDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIK 1473
+S ++TT S P T LL Q G + + S+ L+
Sbjct: 349 PESAG----AATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFD-SKPPTTLLGLIPAP 403
Query: 1474 KEIP-TDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDN 1532
+P TD K PP + P P+ S Q T +S
Sbjct: 404 SMVPATDTK--------APPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPA 455
Query: 1533 RPPALAKFLPNSQELGNTSSSEGEKDSPPPEWDSVPVHKPGSS----TDSLYKLSLQTLN 1588
A F P T+ + EK+ P P SV P SS T S + Q +
Sbjct: 456 ASSAPPMFKPIF-----TAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVF 510
Query: 1589 ADI-----------FLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQP 1637
+ + F KQ T T + + P A + + I ++S S+D K
Sbjct: 511 SSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPA 570
Query: 1638 NGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAPV- 1696
G ++S+ + T + TA G A +S S P
Sbjct: 571 FGFGINSVSSSSV-----STTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPAL 625
Query: 1697 ---DSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSKLGLSRSCNQASQR 1753
+ + S L + V +S FS FG++ + S S+ S
Sbjct: 626 PTTTTVTTFSQSLHTAVPTATSSSAA---DFSGFGSTLATSAPATS----SQPTLTFSNT 678
Query: 1754 SWNEFN-----SGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWSTTPFSSSI 1808
S FN S S L P +P P++ A+ G P A L + F SS
Sbjct: 679 STPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPS--------FGSSF 730
Query: 1809 WSSNLSSALPFTTPA 1823
N ++ TPA
Sbjct: 731 TFGNSAAPAAAPTPA 745
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,905,787
Number of Sequences: 37866
Number of extensions: 4042796
Number of successful extensions: 31828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 1196
Number of HSP's that attempted gapping in prelim test: 21270
Number of HSP's gapped (non-prelim): 8399
length of query: 1883
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1766
effective length of database: 13,817,196
effective search space: 24401168136
effective search space used: 24401168136
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.