Guide to the Human Genome
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Name: AFF4 Sequence: fasta or formatted (1163aa) NCBI GI: 7656879
Description:

ALL1 fused gene from 5q31

Referenced in:

Additional Genes in Development

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         61           3
 C cysteine            0.6          7           1
 D aspartate           5.1         59           2
 E glutamate           7.4         86           3
 F phenylalanine       1.9         22           2
 G glycine             5.1         59           2
 H histidine           2.8         32           2
 I isoleucine          2.2         26           2
 K lysine             10.5        122           3
 L leucine             5.6         65           2
 M methionine          1.8         21           1
 N asparagine          4.6         53           2
 P proline             8.2         95           3
 Q glutamine           4.6         53           2
 R arginine            4.7         55           2
 S serine             18.8        219           4
 T threonine           5.2         60           2
 V valine              3.0         35           2
 W tryptophan          0.6          7           1
 Y tyrosine            2.2         26           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   ALL1 fused gene from 5q31 
AFF1                  0.294   myeloid/lymphoid or mixed-lineage leukemia trithorax ...
AFF3                  0.272   AF4/FMR2 family, member 3 isoform 2 
AFF3                  0.272   AF4/FMR2 family, member 3 isoform 1 
AFF2                  0.265   fragile X mental retardation 2 
DSPP                  0.054   dentin sialophosphoprotein preproprotein 
NEFH                  0.041   neurofilament, heavy polypeptide 200kDa 
SRRM2                 0.037   splicing coactivator subunit SRm300 
RBBP6                 0.031   retinoblastoma-binding protein 6 isoform 2 
RBBP6                 0.031   retinoblastoma-binding protein 6 isoform 1 
FLG                   0.029   filaggrin 
LOC100170229          0.029   hypothetical protein LOC100170229 
SRRM1                 0.027   serine/arginine repetitive matrix 1 
PRG4                  0.026   proteoglycan 4 isoform B 
PRG4                  0.026   proteoglycan 4 isoform A 
DPCR1                 0.026   diffuse panbronchiolitis critical region 1 protein ...
NKTR                  0.025   natural killer-tumor recognition sequence 
GPATCH8               0.025   G patch domain containing 8 
NOLC1                 0.025   nucleolar and coiled-body phosphoprotein 1 
HRNR                  0.024   hornerin 
PPIG                  0.024   peptidylprolyl isomerase G 
SFRS4                 0.024   splicing factor, arginine/serine-rich 4 
MLL                   0.024   myeloid/lymphoid or mixed-lineage leukemia protein [...
MUC12                 0.024   PREDICTED: mucin 12 
ANK2                  0.023   ankyrin 2 isoform 1 
LOC100294236          0.023   PREDICTED: similar to diffuse panbronchiolitis crit...
TRDN                  0.022   triadin 
DMP1                  0.021   dentin matrix acidic phosphoprotein 1 isoform 1 precu...
TCOF1                 0.021   Treacher Collins-Franceschetti syndrome 1 isoform d...
TCOF1                 0.021   Treacher Collins-Franceschetti syndrome 1 isoform b ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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