Guide to the Human Genome
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Search of human proteins with 149192853

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149192853 family with sequence similarity 89, member B
isoform 3 [Homo sapiens]
         (154 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149192853 family with sequence similarity 89, member B isofor...   313   3e-86
gi|22779873 family with sequence similarity 89, member B isoform...   199   1e-51
gi|149192858 family with sequence similarity 89, member B isofor...   197   2e-51
gi|38348390 family with sequence similarity 89, member A [Homo s...    82   1e-16
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    40   8e-04
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    39   0.002
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     38   0.004
gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens]         36   0.011
gi|66912172 hairy and enhancer of split 3 [Homo sapiens]               35   0.033
gi|226371735 iroquois homeobox 3 [Homo sapiens]                        34   0.043
gi|239748977 PREDICTED: hypothetical protein XP_002346843 [Homo ...    34   0.057
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        34   0.057
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       34   0.057
gi|21359951 RNA binding motif protein 42 [Homo sapiens]                33   0.074
gi|17738294 cyclin-dependent kinase inhibitor 2A isoform 4 [Homo...    33   0.097
gi|66773086 SH3-binding kinase 1 [Homo sapiens]                        33   0.097
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    33   0.13 
gi|239752278 PREDICTED: hypothetical protein [Homo sapiens]            32   0.16 
gi|239746791 PREDICTED: hypothetical protein XP_002343850 [Homo ...    32   0.16 
gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]    32   0.16 
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       32   0.22 
gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]                  32   0.28 
gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]            32   0.28 
gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]            32   0.28 
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     32   0.28 
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     32   0.28 
gi|30425446 hypothetical protein LOC255783 [Homo sapiens]              32   0.28 
gi|239753786 PREDICTED: hypothetical protein LOC100129786 [Homo ...    31   0.37 
gi|239750101 PREDICTED: hypothetical protein [Homo sapiens]            31   0.37 
gi|169167301 PREDICTED: hypothetical protein LOC100129786 [Homo ...    31   0.37 

>gi|149192853 family with sequence similarity 89, member B isoform 3
           [Homo sapiens]
          Length = 154

 Score =  313 bits (803), Expect = 3e-86
 Identities = 154/154 (100%), Positives = 154/154 (100%)

Query: 1   MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60
           MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR
Sbjct: 1   MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60

Query: 61  APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRV 120
           APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRV
Sbjct: 61  APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRV 120

Query: 121 NPGLQTPVPRPELLPGPVILPPFGQLLPTGCGPV 154
           NPGLQTPVPRPELLPGPVILPPFGQLLPTGCGPV
Sbjct: 121 NPGLQTPVPRPELLPGPVILPPFGQLLPTGCGPV 154


>gi|22779873 family with sequence similarity 89, member B isoform
          2 [Homo sapiens]
          Length = 176

 Score =  199 bits (505), Expect = 1e-51
 Identities = 98/98 (100%), Positives = 98/98 (100%)

Query: 1  MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60
          MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR
Sbjct: 1  MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60

Query: 61 APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEML 98
          APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEML
Sbjct: 61 APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEML 98


>gi|149192858 family with sequence similarity 89, member B isoform
          1 [Homo sapiens]
          Length = 189

 Score =  197 bits (502), Expect = 2e-51
 Identities = 97/98 (98%), Positives = 98/98 (100%)

Query: 1  MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60
          MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR
Sbjct: 1  MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60

Query: 61 APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEML 98
          APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEM+
Sbjct: 61 APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMV 98


>gi|38348390 family with sequence similarity 89, member A [Homo
          sapiens]
          Length = 184

 Score = 82.4 bits (202), Expect = 1e-16
 Identities = 54/101 (53%), Positives = 63/101 (62%), Gaps = 20/101 (19%)

Query: 9  APGGAG------CALAGLPPLPRGLSGLLN-ASGGS----WRELERVYSQRSRIHDELSR 57
          APG AG        + GLPPLP+ LSGLL+ ASGG     WR LER+Y+Q+SRI DELSR
Sbjct: 7  APGAAGNGAVRGLRVDGLPPLPKSLSGLLHSASGGGASGGWRHLERLYAQKSRIQDELSR 66

Query: 58 AARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEML 98
                GP    G   A  AA P +P NLD+ALA LRKEM+
Sbjct: 67 G-----GP----GGGGARAAALPAKPPNLDAALALLRKEMV 98


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 40.0 bits (92), Expect = 8e-04
 Identities = 41/138 (29%), Positives = 54/138 (39%), Gaps = 14/138 (10%)

Query: 10  PGGAGCALAGLPPLPRGLSGL---LNASGGSWRELERVYSQRSRIHDELSRAARAPDGPR 66
           P G     A L P P G +G    + A+       E   +  ++     + AARA  GP 
Sbjct: 116 PAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175

Query: 67  HAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQT 126
              G    GP  GP +P    +A      + L+   A    H    PAV  V   P    
Sbjct: 176 PGPGP---GPGPGPGKPAGPGAA------QTLNGSAALLNSHHAAAPAVSLVNNGPAALL 226

Query: 127 PVPRPELLPGPVI-LPPF 143
           P+P+P   PG VI  PPF
Sbjct: 227 PLPKP-AAPGTVIQTPPF 243



 Score = 27.7 bits (60), Expect = 4.1
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 17/86 (19%)

Query: 68  AAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQTP 127
           AA AA+    A PR P    +A  AL   ++S   A A G        GP     G    
Sbjct: 34  AASAAHHHHLA-PRTPEVRAAAAGALGNHVVSGSPAGAAG-------AGPAAPAEGAPGA 85

Query: 128 VPRPELLPGPVILPPFGQLLPTGCGP 153
            P P         PP G+  P G GP
Sbjct: 86  APEP---------PPAGRARPGGGGP 102



 Score = 26.6 bits (57), Expect = 9.1
 Identities = 34/116 (29%), Positives = 38/116 (32%), Gaps = 30/116 (25%)

Query: 65  PRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAV------GHVLVVPAVG-- 116
           P H AG   A PA  P        +  A      +AGG A V      G     PA G  
Sbjct: 284 PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343

Query: 117 ---PVRV----NPGLQT------------PVPRPEL---LPGPVILPPFGQLLPTG 150
              P RV     P  QT             V  P +   LP P  +PP     PTG
Sbjct: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTG 399


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 43/154 (27%), Positives = 67/154 (43%), Gaps = 12/154 (7%)

Query: 1   MNGLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60
           + GLP+  +PGGA  A  GL P+      ++  +  +     ++ +++  +   L+ AA 
Sbjct: 214 LQGLPNG-SPGGATAATLGLAPIQVVGQPVMALNTPT----SQLLAKQVPVSGYLASAA- 267

Query: 61  APDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRV 120
            P  P   A A  +   AG     NL +A+A         GGA A       P+  P+ V
Sbjct: 268 GPSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAV 327

Query: 121 NPGLQTP--VPRPELL----PGPVILPPFGQLLP 148
            PGL +   VP P ++    P P+   P G L P
Sbjct: 328 APGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPP 361


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 37.7 bits (86), Expect = 0.004
 Identities = 31/85 (36%), Positives = 36/85 (42%), Gaps = 10/85 (11%)

Query: 58  AARAPD-GPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVG 116
           AA AP   PR AA AA A P+ GP +P        A R   L+A   A      V P  G
Sbjct: 141 AAAAPARAPRAAAAAATAPPSPGPAQP-----GPRAQRAAPLAAPPPAPAAPPAVAPPAG 195

Query: 117 PVRVNP----GLQTPVPRPELLPGP 137
           P R  P      + P+P P   P P
Sbjct: 196 PRRAPPPAVAAREPPLPPPPQPPAP 220



 Score = 33.9 bits (76), Expect = 0.057
 Identities = 29/89 (32%), Positives = 35/89 (39%), Gaps = 10/89 (11%)

Query: 60  RAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVR 119
           RAP G   AA AA   P   P  P    +A A  R    +A  A A       P+ GP +
Sbjct: 113 RAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP------PSPGPAQ 166

Query: 120 VNPGLQ--TPVPRPELLPG--PVILPPFG 144
             P  Q   P+  P   P   P + PP G
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195


>gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens]
          Length = 566

 Score = 36.2 bits (82), Expect = 0.011
 Identities = 42/155 (27%), Positives = 51/155 (32%), Gaps = 34/155 (21%)

Query: 6   SAEAPGGAGCALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGP 65
           +A    G+ C  AG+ P      G     G  WR                    R   GP
Sbjct: 68  AAREQSGSPCRAAGVSP------GTGGREGAEWRA-----------------GGREGPGP 104

Query: 66  RHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVG--HVLVVPAVGPVRVNPG 123
             +   + A PA    R   L+  L++        GGAAAV      V PA  P    PG
Sbjct: 105 SPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAP---TPG 161

Query: 124 ------LQTPVPRPELLPGPVILPPFGQLLPTGCG 152
                 L+ P P P L P P  L    Q L    G
Sbjct: 162 EQFLLPLRAPFPEPALQPDPAPLSAALQSLKRAAG 196


>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
          Length = 186

 Score = 34.7 bits (78), Expect = 0.033
 Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 10/117 (8%)

Query: 16  ALAGLPPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGAANAG 75
           +L GL P+PRG           +R      SQ  R  DE+    R P  P  AAG+    
Sbjct: 52  SLQGLWPVPRGAE-----QPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDS 106

Query: 76  PAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQTPVPRPE 132
              G   P        A+     +AGG  +   +L++P        PG    VP P+
Sbjct: 107 AGLGQEAPALFRPCTPAVWAPAPAAGGPRSPPPLLLLP-----ESLPGSSASVPPPQ 158


>gi|226371735 iroquois homeobox 3 [Homo sapiens]
          Length = 501

 Score = 34.3 bits (77), Expect = 0.043
 Identities = 45/154 (29%), Positives = 55/154 (35%), Gaps = 23/154 (14%)

Query: 4   LPSAEAPGGAGCALAGLPPLPRGLSGLLNASG-GSWRELERVYSQRSRIHDELSRAARAP 62
           L  A AP     A   LP  P  L     A    S  +  +++S        L+  A +P
Sbjct: 308 LSLAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWS--------LAETATSP 359

Query: 63  DGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVG--PVRV 120
           D PR +   A   P      P    SAL       LS   AAA  H LV   +G  P   
Sbjct: 360 DNPRRSPPGAGGSPPGAAVAP----SAL------QLSPAAAAAAAHRLVSAPLGKFPAWT 409

Query: 121 NPGLQTPVPRPELLPGPVI--LPPFGQLLPTGCG 152
           N     P P P L P  ++   PP    LP   G
Sbjct: 410 NRPFPGPPPGPRLHPLSLLGSAPPHLLGLPGAAG 443


>gi|239748977 PREDICTED: hypothetical protein XP_002346843 [Homo
           sapiens]
          Length = 106

 Score = 33.9 bits (76), Expect = 0.057
 Identities = 24/66 (36%), Positives = 35/66 (53%), Gaps = 5/66 (7%)

Query: 91  AALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQT-PVPRPELLPGP--VILPPF--GQ 145
           ++++   ++ GG+ A G       + P+ + P L   P P PELLP P  V+LPP   G 
Sbjct: 16  SSMKSVSMTLGGSIAAGTWATEAGMLPLPLPPPLLLLPAPPPELLPEPPGVLLPPEPPGV 75

Query: 146 LLPTGC 151
           LLP  C
Sbjct: 76  LLPPLC 81


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 33.9 bits (76), Expect = 0.057
 Identities = 30/80 (37%), Positives = 33/80 (41%), Gaps = 14/80 (17%)

Query: 58  AARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGP 117
           AA AP     AA AA   PAA  + P     A AA      SA  AAAV           
Sbjct: 514 AAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP--SAAAAAAV----------- 560

Query: 118 VRVNPGLQTPVPRPELLPGP 137
            +V P    PVP P L+P P
Sbjct: 561 -QVAPAAPAPVPAPALVPVP 579


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 33.9 bits (76), Expect = 0.057
 Identities = 30/80 (37%), Positives = 33/80 (41%), Gaps = 14/80 (17%)

Query: 58  AARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGP 117
           AA AP     AA AA   PAA  + P     A AA      SA  AAAV           
Sbjct: 923 AAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAP--SAAAAAAV----------- 969

Query: 118 VRVNPGLQTPVPRPELLPGP 137
            +V P    PVP P L+P P
Sbjct: 970 -QVAPAAPAPVPAPALVPVP 988


>gi|21359951 RNA binding motif protein 42 [Homo sapiens]
          Length = 480

 Score = 33.5 bits (75), Expect = 0.074
 Identities = 36/102 (35%), Positives = 41/102 (40%), Gaps = 19/102 (18%)

Query: 59  ARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAV--- 115
           ARAP GP   + AA   P   P  P  L   L    KE   A  AAA G      AV   
Sbjct: 211 ARAP-GPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVG 269

Query: 116 ------GPVRVNPGLQT----PVPRPELLPGPV-----ILPP 142
                 GP  + P L      P+P PE LP P+     +LPP
Sbjct: 270 AGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPP 311


>gi|17738294 cyclin-dependent kinase inhibitor 2A isoform 4 [Homo
           sapiens]
          Length = 173

 Score = 33.1 bits (74), Expect = 0.097
 Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 3/67 (4%)

Query: 19  GLPPLPR--GLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDG-PRHAAGAANAG 75
           G  PLPR  G       SGG+     R    R   H   +RA R P G P HA GAA   
Sbjct: 97  GQQPLPRRPGHDDGQRPSGGAAAAPRRGAQLRRPRHSHPTRARRCPGGLPGHAGGAAPGR 156

Query: 76  PAAGPRR 82
            AAG  R
Sbjct: 157 GAAGRAR 163


>gi|66773086 SH3-binding kinase 1 [Homo sapiens]
          Length = 424

 Score = 33.1 bits (74), Expect = 0.097
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 15/93 (16%)

Query: 49  SRIHDELSRAARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKEMLSAGGAAAVGH 108
           S +    S  AR P G R         PAAGP R      A   L++ +L+  G+   G 
Sbjct: 319 SELRRRPSHRARKPPGDRP--------PAAGPLRL----EAPGPLKRTVLTESGS---GS 363

Query: 109 VLVVPAVGPVRVNPGLQTPVPRPELLPGPVILP 141
               PAVG V +   +  PVP P  +P P + P
Sbjct: 364 RPAPPAVGSVPLPVPVPVPVPVPVPVPEPGLAP 396


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 32.7 bits (73), Expect = 0.13
 Identities = 45/159 (28%), Positives = 57/159 (35%), Gaps = 30/159 (18%)

Query: 6    SAEAPGGAGCALAGLPPLPRGLSGLLN--ASGGSWRELERVYSQRSRIHDELSRAARAPD 63
            SA   GGAG  +A  P L       L+  A GGS        +       +L   ++   
Sbjct: 1707 SAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS-------STPGPPYPPQLMTPSKLRG 1759

Query: 64   GPRHAAGAANAGPAAGPRRPVNLDS-----------ALAALRKEMLSAGGAAAVGHVLVV 112
                A+G    GP+ G R PV   S            L ALR          A G V V 
Sbjct: 1760 RALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVE 1819

Query: 113  PAVGPV----------RVNPGLQTPVPRPELLPGPVILP 141
            P V PV          ++ P  + P P P  LPGP+  P
Sbjct: 1820 PEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQP 1858


>gi|239752278 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 252

 Score = 32.3 bits (72), Expect = 0.16
 Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 3   GLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGG---SWRELERVYSQRSRIHDELSRAA 59
           GLP + APG  G     LP LP  LS + + SGG   +W     + +       E     
Sbjct: 168 GLPGSRAPGLPGSRFFALPSLPPPLSVVTSRSGGPGAAWLARAPLRAAGEIQVSERVEPQ 227

Query: 60  RAPDGPRHAAGAANAG 75
            A   PR A G A  G
Sbjct: 228 GARGSPRGADGLAKLG 243


>gi|239746791 PREDICTED: hypothetical protein XP_002343850 [Homo
           sapiens]
          Length = 252

 Score = 32.3 bits (72), Expect = 0.16
 Identities = 25/76 (32%), Positives = 31/76 (40%), Gaps = 3/76 (3%)

Query: 3   GLPSAEAPGGAGCALAGLPPLPRGLSGLLNASGG---SWRELERVYSQRSRIHDELSRAA 59
           GLP + APG  G     LP LP  LS + + SGG   +W     + +       E     
Sbjct: 168 GLPGSRAPGLPGSRFFALPSLPPPLSVVTSRSGGPGAAWLARAPLRAAGEIQVSERVEPQ 227

Query: 60  RAPDGPRHAAGAANAG 75
            A   PR A G A  G
Sbjct: 228 GARGSPRGADGLAKLG 243


>gi|40288203 hypothetical protein LOC219287 isoform 1 [Homo sapiens]
          Length = 671

 Score = 32.3 bits (72), Expect = 0.16
 Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 9/78 (11%)

Query: 51  IHDELSRAARAPDGPRHAAGAANAG-PAAGPRRPVNLDSALAALRKEM--------LSAG 101
           + +E  RAAR P+ P   A    AG PA G   P   D A A   +E           A 
Sbjct: 237 VKEETPRAAREPEEPSQDAPRDPAGEPAGGEEVPAPADRAPARSCREAEGLAHPGDTGAR 296

Query: 102 GAAAVGHVLVVPAVGPVR 119
           G  A GH    P  G VR
Sbjct: 297 GEDAAGHRRAEPGPGEVR 314


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 32.0 bits (71), Expect = 0.22
 Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 10/132 (7%)

Query: 21  PPLPRGLSGLLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGAANAGPAAGP 80
           P LP   + L + S     +   VYS        +   + A   P  A    +   + GP
Sbjct: 601 PTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP 660

Query: 81  RRPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQTPVPRPELLPGPVIL 140
             P +L S L A ++   + G        L V +V      P LQ   P P +   PV L
Sbjct: 661 VLPQSLPS-LGAYQQPTAAPG--------LPVGSVPAPACPPSLQQHFPDPAMSFAPV-L 710

Query: 141 PPFGQLLPTGCG 152
           PP    +PTG G
Sbjct: 711 PPPSTPMPTGPG 722


>gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]
          Length = 422

 Score = 31.6 bits (70), Expect = 0.28
 Identities = 44/134 (32%), Positives = 55/134 (41%), Gaps = 28/134 (20%)

Query: 6   SAEAPGGAGCALAGLPPLPRGLSGLLNA--SGGSWRELE---------RVYSQRSRIHDE 54
           +A APG A    AG    P G S   ++  S GS +EL          +V+ QR R    
Sbjct: 42  AALAPGAA----AGNEAAPAGASVCYSSPPSVGSVQELAQRAAVVIEGKVHPQR-RQQGA 96

Query: 55  LSRAARAPDGPRHAAGAANAGPAAGPRRPVNLDSALAALRKE-MLSAGGAAAVGHVLVVP 113
           L R A A  G   A G     PAAGPR       AL    +E +L+A G         VP
Sbjct: 97  LDRKAAAAAGEAGAWGGDREPPAAGPR-------ALGPPAEEPLLAANGTVPSWPTAPVP 149

Query: 114 AVGPVRVNPGLQTP 127
           + G     PG + P
Sbjct: 150 SAG----EPGEEAP 159


>gi|239749482 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 195

 Score = 31.6 bits (70), Expect = 0.28
 Identities = 34/100 (34%), Positives = 41/100 (41%), Gaps = 14/100 (14%)

Query: 58  AARAPDGPRHAAGAA--NAGPAAGPRRPVNLDSA-----LAALRKEMLSAGGAAAVGHVL 110
           AA  P  PR    AA  +A  AA PRR            +A+     L   GA AV    
Sbjct: 53  AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP--- 109

Query: 111 VVPAVGPVRVNPGLQTPVPRPELLPGP--VILPPFGQLLP 148
             P+ GP+   P   +P PRP L  GP   +LPP     P
Sbjct: 110 AAPSPGPLPARP--SSPPPRPSLPSGPHRPVLPPSALAAP 147


>gi|239743620 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 31.6 bits (70), Expect = 0.28
 Identities = 34/100 (34%), Positives = 41/100 (41%), Gaps = 14/100 (14%)

Query: 58  AARAPDGPRHAAGAA--NAGPAAGPRRPVNLDSA-----LAALRKEMLSAGGAAAVGHVL 110
           AA  P  PR    AA  +A  AA PRR            +A+     L   GA AV    
Sbjct: 53  AAAHPPAPRERPAAARLSALAAAQPRRRSPGPQGGGGGDIASPLPPALQPRGAPAVP--- 109

Query: 111 VVPAVGPVRVNPGLQTPVPRPELLPGP--VILPPFGQLLP 148
             P+ GP+   P   +P PRP L  GP   +LPP     P
Sbjct: 110 AAPSPGPLPARP--SSPPPRPSLPSGPHRPVLPPSALAAP 147


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 31.6 bits (70), Expect = 0.28
 Identities = 34/112 (30%), Positives = 44/112 (39%), Gaps = 7/112 (6%)

Query: 24  PRGLSGLLNASGGSWRELERV-YSQRSRIHDELSRAARAPDGP-RHAAGAANAGPAAGPR 81
           P   S L N       EL++    QR     E + AA A  G  + AAG  + GPA GP 
Sbjct: 7   PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66

Query: 82  RPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQTPVPRPEL 133
           +P+  +    A        GGA + G     P +     N G     PRP L
Sbjct: 67  QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAG-----PRPAL 113


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 31.6 bits (70), Expect = 0.28
 Identities = 34/112 (30%), Positives = 44/112 (39%), Gaps = 7/112 (6%)

Query: 24  PRGLSGLLNASGGSWRELERV-YSQRSRIHDELSRAARAPDGP-RHAAGAANAGPAAGPR 81
           P   S L N       EL++    QR     E + AA A  G  + AAG  + GPA GP 
Sbjct: 7   PAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGPP 66

Query: 82  RPVNLDSALAALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQTPVPRPEL 133
           +P+  +    A        GGA + G     P +     N G     PRP L
Sbjct: 67  QPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAG-----PRPAL 113


>gi|30425446 hypothetical protein LOC255783 [Homo sapiens]
          Length = 142

 Score = 31.6 bits (70), Expect = 0.28
 Identities = 25/72 (34%), Positives = 31/72 (43%), Gaps = 6/72 (8%)

Query: 5   PSAEAPGGAGCALAGLPPLP----RGLSGLLNASGGSWRELERVYSQRSRIHDELSRAAR 60
           P   AP     A  G+PP+P      LS LL   GG   +L+   S+R R  D   R +R
Sbjct: 67  PQPSAPSPPCAARPGVPPVPAPAAASLSCLLGVPGGPRPQLQLPLSRRRRYSDPDRRPSR 126

Query: 61  APDGPRHAAGAA 72
               PR    AA
Sbjct: 127 --QTPRETPEAA 136


>gi|239753786 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score = 31.2 bits (69), Expect = 0.37
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 46  SQRSRIHDELSRAARAPDGPRHAAGAANAGPAAG---PRRPVNLDSALA 91
           S R     +L RA ++P  PR A G+    PA     PR+P N + A A
Sbjct: 115 STRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARA 163


>gi|239750101 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 365

 Score = 31.2 bits (69), Expect = 0.37
 Identities = 29/116 (25%), Positives = 42/116 (36%), Gaps = 6/116 (5%)

Query: 30  LLNASGGSWRELERVYSQRSRIHDELSRAARAPDGPRHAAGAANAGPAAGPRRPVNLDSA 89
           LL    G  R++E++  +      +      APDG  H  G+  +G AA   RP    +A
Sbjct: 232 LLPVQSGQQRQVEQLQHRHQHERGQQQLVEGAPDGVGHLHGSRGSGRAATTTRPQTTPAA 291

Query: 90  LAALRKEMLSAGGAAAVGHVLVVPAVGPVRVNPGLQTPVPRPELLPGPVILPPFGQ 145
            +      L      + G         P R  P  + P P P   PG    P  G+
Sbjct: 292 AS----PDLPQPAERSRGEPRPAEPRAPPRPPPAARRPPPPP--APGAPARPLRGR 341


>gi|169167301 PREDICTED: hypothetical protein LOC100129786 [Homo
           sapiens]
          Length = 210

 Score = 31.2 bits (69), Expect = 0.37
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 46  SQRSRIHDELSRAARAPDGPRHAAGAANAGPAAG---PRRPVNLDSALA 91
           S R     +L RA ++P  PR A G+    PA     PR+P N + A A
Sbjct: 115 STRESQETDLRRARQSPRNPRRARGSPGNRPAQSTREPRKPTNAEHARA 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.138    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,206,100
Number of Sequences: 37866
Number of extensions: 453287
Number of successful extensions: 2849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 179
Number of HSP's that attempted gapping in prelim test: 2677
Number of HSP's gapped (non-prelim): 349
length of query: 154
length of database: 18,247,518
effective HSP length: 93
effective length of query: 61
effective length of database: 14,725,980
effective search space: 898284780
effective search space used: 898284780
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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