Guide to the Human Genome
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Name: NRG1 Sequence: fasta or formatted (422aa) NCBI GI: 116006967
Description:

neuregulin 1 isoform GGF2

Referenced in:

Epidermal Growth Factor
Gene Structure
Neurons

Other entries for this name:
alt prot [645aa] neuregulin 1 isoform HRG-beta1
alt prot [637aa] neuregulin 1 isoform HRG-beta2
alt prot [241aa] neuregulin 1 isoform HRG-beta3
alt prot [211aa] neuregulin 1 isoform HRG-gamma
alt prot [607aa] neuregulin 1 isoform HRG-beta1c
alt prot [308aa] neuregulin 1 isoform ndf43c
alt prot [624aa] neuregulin 1 isoform HRG-beta1b
alt prot [590aa] neuregulin 1 isoform HRG-beta1d
alt prot [194aa] neuregulin 1 isoform HRG-gamma2
alt prot [459aa] neuregulin 1 isoform ndf43b
alt prot [207aa] neuregulin 1 isoform HRG-beta3b
alt prot [177aa] neuregulin 1 isoform HRG-gamma3
alt prot [420aa] neuregulin 1 isoform HRG-beta2b
alt prot [296aa] neuregulin 1 isoform SMDF
alt prot [462aa] neuregulin 1 isoform ndf43
alt prot [640aa] neuregulin 1 isoform HRG-alpha
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            12.3         52           5
 C cysteine            2.8         12           1
 D aspartate           2.1          9           1
 E glutamate           6.4         27           2
 F phenylalanine       2.8         12           2
 G glycine             8.1         34           2
 H histidine           0.9          4           1
 I isoleucine          1.9          8           1
 K lysine              6.9         29           2
 L leucine             8.8         37           5
 M methionine          1.4          6           1
 N asparagine          4.0         17           1
 P proline             9.2         39           2
 Q glutamine           2.6         11           2
 R arginine            7.1         30           2
 S serine              9.7         41           2
 T threonine           4.3         18           2
 V valine              5.2         22           2
 W tryptophan          1.4          6           1
 Y tyrosine            1.9          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neuregulin 1 isoform GGF2 
NRG1                  0.397   neuregulin 1 isoform HRG-beta3b 
NRG1                  0.375   neuregulin 1 isoform HRG-beta3 
NRG1                  0.371   neuregulin 1 isoform HRG-beta1d 
NRG1                  0.359   neuregulin 1 isoform HRG-beta1c 
NRG1                  0.350   neuregulin 1 isoform ndf43b 
NRG1                  0.350   neuregulin 1 isoform HRG-beta2b 
NRG1                  0.350   neuregulin 1 isoform HRG-beta2 
NRG1                  0.350   neuregulin 1 isoform HRG-beta1 
NRG1                  0.349   neuregulin 1 isoform HRG-beta1b 
NRG1                  0.320   neuregulin 1 isoform HRG-gamma3 
NRG1                  0.314   neuregulin 1 isoform HRG-alpha 
NRG1                  0.314   neuregulin 1 isoform ndf43 
NRG1                  0.307   neuregulin 1 isoform HRG-gamma2 
NRG1                  0.298   neuregulin 1 isoform HRG-gamma 
NRG2                  0.206   neuregulin 2 isoform 2 
NRG2                  0.206   neuregulin 2 isoform 4 
NRG2                  0.196   neuregulin 2 isoform 3 
NRG2                  0.196   neuregulin 2 isoform 1 
NRG1                  0.162   neuregulin 1 isoform SMDF 
NRG1                  0.105   neuregulin 1 isoform ndf43c 
NTM                   0.037   neurotrimin isoform 2 
NTM                   0.037   neurotrimin isoform 1 
TTN                   0.035   titin isoform N2-A 
NTM                   0.034   neurotrimin isoform 3 
NRG3                  0.031   neuregulin 3 
LSAMP                 0.031   limbic system-associated membrane protein 
NTM                   0.030   neurotrimin isoform 4 
TTN                   0.030   titin isoform novex-2 
TTN                   0.030   titin isoform novex-1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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