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Search of human proteins with 148664190
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148664190 immunoglobulin superfamily, member 4D isoform 1
[Homo sapiens]
(442 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 884 0.0
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 812 0.0
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 342 4e-94
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 290 2e-78
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 277 2e-74
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 271 1e-72
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 118 1e-26
gi|51593098 class-I MHC-restricted T cell associated molecule [H... 94 2e-19
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 87 4e-17
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 86 5e-17
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 84 2e-16
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 84 2e-16
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 84 2e-16
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 84 2e-16
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 84 3e-16
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 82 7e-16
gi|166295173 kin of IRRE like [Homo sapiens] 80 5e-15
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 79 8e-15
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 79 8e-15
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 79 8e-15
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 78 2e-14
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 77 3e-14
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 76 5e-14
gi|110349719 titin isoform N2-A [Homo sapiens] 75 9e-14
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 75 9e-14
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 75 9e-14
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 75 9e-14
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 75 9e-14
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 75 1e-13
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 75 2e-13
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 884 bits (2283), Expect = 0.0
Identities = 442/442 (100%), Positives = 442/442 (100%)
Query: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA
Sbjct: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
Query: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG
Sbjct: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
Query: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF
Sbjct: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
Query: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ
Sbjct: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI
Sbjct: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
Query: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITD 360
NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITD
Sbjct: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITD 360
Query: 361 SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA 420
SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA
Sbjct: 361 SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA 420
Query: 421 DTAIINAEGGQNNSEEKKEYFI 442
DTAIINAEGGQNNSEEKKEYFI
Sbjct: 421 DTAIINAEGGQNNSEEKKEYFI 442
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 812 bits (2098), Expect = 0.0
Identities = 414/442 (93%), Positives = 414/442 (93%), Gaps = 28/442 (6%)
Query: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA
Sbjct: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
Query: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG
Sbjct: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
Query: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF
Sbjct: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
Query: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ
Sbjct: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI
Sbjct: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
Query: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITD 360
NNLNKTDNGTYRCEASNIVGKAHSDYMLYVY D
Sbjct: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVY----------------------------D 332
Query: 361 SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA 420
SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA
Sbjct: 333 SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA 392
Query: 421 DTAIINAEGGQNNSEEKKEYFI 442
DTAIINAEGGQNNSEEKKEYFI
Sbjct: 393 DTAIINAEGGQNNSEEKKEYFI 414
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 342 bits (877), Expect = 4e-94
Identities = 189/415 (45%), Positives = 261/415 (62%), Gaps = 19/415 (4%)
Query: 44 GQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFS 103
GQ T++VTV+EG A ++C+V+++D++ +Q NP +QT+YF D + L+D+R +L+ S
Sbjct: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRAS 85
Query: 104 SSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIE 163
EL +S+++VS+SDEG+Y C L+T P + S +TVL P I +EG+ ++
Sbjct: 86 WHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQ 145
Query: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWS---DMYTVTSQLMLKVHKEDDGVPVIC 220
+ C SKPA IRWFK + E+K ++E +TV+S L +V + DDGV VIC
Sbjct: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
Query: 221 QVEHPAVTGNLQ-TQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
+V+H ++ Q + LE+ Y P V I P +EG L LTCE+ GKP P V
Sbjct: 206 RVDHESLNATPQVAMQVLEIHYTPSVKI---IPSTPFPQEGQPLILTCESKGKPLPEPVL 262
Query: 280 WVRVDDEM--PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
W + E+ P V+SG L I LNKTDNGTYRCEA+N +G++ ++Y+L V+D P T+
Sbjct: 263 WTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
Query: 338 PPPTTTTTTTTTTTTTILTIITD-SRAGEEGSIR---------AVDHAVIGGVVAVVVFA 387
P T + TT T TT + I T + + SIR DHA+IGG+VAVVVF
Sbjct: 323 LPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFV 382
Query: 388 MLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 442
LC + +LGRY ARHKGTY T+EAKGA+DA DADTAIINAEG Q N+EEKKEYFI
Sbjct: 383 TLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 290 bits (741), Expect = 2e-78
Identities = 158/416 (37%), Positives = 242/416 (58%), Gaps = 40/416 (9%)
Query: 29 LLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRD 88
LLLL++AAA G GQ + T++VTV EG VA I+C++++ D S++ + NP RQT++F
Sbjct: 11 LLLLWAAAA--GPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNG 68
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLM 148
R LKD RFQL FS +++ L++ + DEG YFCQLYT+ T+TVLV P N +
Sbjct: 69 TRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPV 128
Query: 149 IDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLK 208
+++ ++ AVEG E+E++C S+PA T+RW++ ELKG S +E +++V S + +
Sbjct: 129 VEV-REQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVRFR 187
Query: 209 VHKEDDGVPVICQVEHPAVTG--NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELT 266
V ++DDG +IC+ ++ A+ + QTQ L+VQY P I + Q + REGD L LT
Sbjct: 188 VDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHAS---QAVVREGDTLVLT 244
Query: 267 CEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDY 326
C G P+P + W R ++ +P+ A G L + L DNGTY CEASN G A + Y
Sbjct: 245 CAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALY 304
Query: 327 MLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRAGEEGSIRAVDHAVIGGVVAVVVF 386
+L VYDP + T +V +A++GG++A++VF
Sbjct: 305 VLVVYDPGAVVEAQT-----------------------------SVPYAIVGGILALLVF 335
Query: 387 AMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 442
++C+L+ + R KG+Y THEA G D+ +A A +N G + + K+E+FI
Sbjct: 336 LIICVLVGMVWCSVRQKGSYLTHEASGLDEQGEAREAFLN---GSDGHKRKEEFFI 388
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 277 bits (708), Expect = 2e-74
Identities = 166/430 (38%), Positives = 239/430 (55%), Gaps = 44/430 (10%)
Query: 22 PGLRLRLLLLLFSAAALIPTG-----DGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQL 76
P L LLLLLF A P G D +T D TV+ G + CQV +DS +Q
Sbjct: 4 PAASLLLLLLLF-ACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQW 62
Query: 77 LNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT 136
NP +QT+YF + R L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + +
Sbjct: 63 SNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKS 122
Query: 137 TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEW 195
+TVL P+ +I K + E + +NC + SKPA + W KG+ EL G+ + ++E
Sbjct: 123 LVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQED 182
Query: 196 SD--MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYP 252
+ +TV+S + +V +EDDG ++C V H ++ G + T + +EV Y P I+ P
Sbjct: 183 PNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP 242
Query: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 312
REG L L CE G P P W + + +P + L LNK+D+GTY
Sbjct: 243 ---HPREGQKLLLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYG 298
Query: 313 CEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRAGEEGSIRAV 372
C A++ +G + Y L V DP P P++++T
Sbjct: 299 CTATSNMGSYKAYYTLNVNDPS---PVPSSSSTY-------------------------- 329
Query: 373 DHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQN 432
HA+IGG+VA +VF +L +LI LG Y RHKGTY THEAKG+DDA DADTAIINAEGGQ+
Sbjct: 330 -HAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQS 388
Query: 433 NSEEKKEYFI 442
++KKEYFI
Sbjct: 389 GGDDKKEYFI 398
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 271 bits (692), Expect = 1e-72
Identities = 157/415 (37%), Positives = 236/415 (56%), Gaps = 39/415 (9%)
Query: 32 LFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRP 91
++S+ ++ + D Q +T D TV+ G + CQV +DS +Q NP +QT+YF + R
Sbjct: 53 VWSSPDMLASQDSQP-WTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRA 111
Query: 92 LKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDI 151
L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + + +TVL P+ +I
Sbjct: 112 LRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG 171
Query: 152 QKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEWSD--MYTVTSQLMLK 208
K + E + +NC + SKPA + W KG+ EL G+ + ++E + +TV+S + +
Sbjct: 172 YKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQ 231
Query: 209 VHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTC 267
V +EDDG ++C V H ++ G + T + +EV Y P I+ P REG L L C
Sbjct: 232 VTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP---HPREGQKLLLHC 288
Query: 268 EAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYM 327
E G P P W + + +P + L LNK+D+GTY C A++ +G + Y
Sbjct: 289 EGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYT 347
Query: 328 LYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRAGEEGSIRAVDHAVIGGVVAVVVFA 387
L V DP P P++++T HA+IGG+VA +VF
Sbjct: 348 LNVNDPS---PVPSSSSTY---------------------------HAIIGGIVAFIVFL 377
Query: 388 MLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 442
+L +LI LG Y RHKGTY THEAKG+DDA DADTAIINAEGGQ+ ++KKEYFI
Sbjct: 378 LLIMLIFLGHYLIRHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 432
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 118 bits (295), Expect = 1e-26
Identities = 109/439 (24%), Positives = 195/439 (44%), Gaps = 43/439 (9%)
Query: 3 SVVLPSGSQCAAAAAAAAPPGLRLR------LLLLLFSA---AALIPTGDGQNLFTKDVT 53
S + P G + ++A+ GL L+ LLLLLF + L G + VT
Sbjct: 8 SPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPIIVEPHVT 67
Query: 54 VIEGEVATISC--QVNKSDDSVI--QLLNPNRQTI------YFRDFRPLKDSRFQLLNFS 103
+ G+ ++ C +VN++ + ++ + QT+ Y + R N+S
Sbjct: 68 AVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYS 127
Query: 104 SSELKVSLTNVSISDEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDTAVEG-- 159
++ ++L N+ SD G+Y C+ T P +S TT+TVLV P +I D+ ++G
Sbjct: 128 LNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIK-GPDSLIDGGN 186
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
E + C A KP I W +G+ + ++ T+ SQ L + G +
Sbjct: 187 ETVAAICIAATGKPVAHIDW-EGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRIT 245
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
C V+HPA+ +++ L++QY P+V + + R+G + L C A P P
Sbjct: 246 CVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG--VNLKCNADANPPPFKSV 303
Query: 280 WVRVDDEMPQHAVLSGPNL-FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP 338
W R+D + P + S L F++ L +G Y C+ +N +G+ ++Y+ DPPTT
Sbjct: 304 WSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTT 363
Query: 339 --------PPTTTTTTTTTTTTTILTIITDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLC 390
P T T + ++ ++ +I + +V+GG + +V+ ++L
Sbjct: 364 LQPTIQWHPSTADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLA 423
Query: 391 LLI-------ILGRYFARH 402
+ G YFA++
Sbjct: 424 GIFCYRRRRTFRGDYFAKN 442
>gi|51593098 class-I MHC-restricted T cell associated molecule [Homo
sapiens]
Length = 393
Score = 94.0 bits (232), Expect = 2e-19
Identities = 55/183 (30%), Positives = 94/183 (51%), Gaps = 2/183 (1%)
Query: 49 TKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELK 108
T+ +TV EG+ T+ C + +S +Q L P+ TI+ ++ LK+S++QLL+ S+++L
Sbjct: 23 TETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFLNEYPALKNSKYQLLHHSANQLS 82
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEE-IEVNCT 167
+++ NV++ DEG Y C Y+D + VL P +++ GEE + + C+
Sbjct: 83 ITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFKPILEASVIRKQNGEEHVVLMCS 142
Query: 168 AMASKPATTIRWFKGNT-ELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
M SKP I W GN+ E+ G + E +D + L +H V C + H
Sbjct: 143 TMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTTSTLIIHTYGKNSTVDCIIRHRG 202
Query: 227 VTG 229
+ G
Sbjct: 203 LQG 205
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 86.7 bits (213), Expect = 4e-17
Identities = 67/251 (26%), Positives = 102/251 (40%), Gaps = 6/251 (2%)
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146
F K S Q + ++L +++ DEG Y C+ T P T + V+ P+N
Sbjct: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
Query: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205
+ QK T + C + +P I W + E K + TVTS+
Sbjct: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
Query: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265
L DGV V C+VEH + L V+Y P+V I Y DA L
Sbjct: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
Query: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325
+C+ P+P W P AV G L I+ ++ N T+ C +N VG ++
Sbjct: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
Query: 326 YMLYVYDPPTT 336
+++V + P T
Sbjct: 342 QVIFVRETPNT 352
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 86.3 bits (212), Expect = 5e-17
Identities = 67/253 (26%), Positives = 102/253 (40%), Gaps = 6/253 (2%)
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146
F K S Q + ++L +++ DEG Y C+ T P T + V+ P+N
Sbjct: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
Query: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205
+ QK T + C + +P I W + E K + TVTS+
Sbjct: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
Query: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265
L DGV V C+VEH + L V+Y P+V I Y DA L
Sbjct: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
Query: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325
+C+ P+P W P AV G L I+ ++ N T+ C +N VG ++
Sbjct: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
Query: 326 YMLYVYDPPTTIP 338
+++V + P P
Sbjct: 342 QVIFVRETPRASP 354
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 84.3 bits (207), Expect = 2e-16
Identities = 84/321 (26%), Positives = 136/321 (42%), Gaps = 30/321 (9%)
Query: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
Query: 132 QESYTTITVLVPPRNLMIDIQKDT-AVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
Query: 188 GKSEVEEWSD---MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYHM--DRFKESLTLNVQYEPE 248
Query: 245 VHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINN-L 303
V I+ L R ++LTC+A P W ++ +P+ LF +
Sbjct: 249 VTIEGFDGNWYLQRMD--VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFKGPI 306
Query: 304 NKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRA 363
N + GTY CEA+N +G + + + P T PP T I
Sbjct: 307 NYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAII--------G 358
Query: 364 GEEGSIRAVDHAVIGGVVAVV 384
G GSI V V+GG+V +
Sbjct: 359 GVAGSILLV-LIVVGGIVVAL 378
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 84.3 bits (207), Expect = 2e-16
Identities = 94/340 (27%), Positives = 138/340 (40%), Gaps = 27/340 (7%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
G L I ++K N T C +N +G ++ + V + P
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 84.3 bits (207), Expect = 2e-16
Identities = 94/340 (27%), Positives = 138/340 (40%), Gaps = 27/340 (7%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
G L I ++K N T C +N +G ++ + V + P
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 84.3 bits (207), Expect = 2e-16
Identities = 94/340 (27%), Positives = 138/340 (40%), Gaps = 27/340 (7%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
G L I ++K N T C +N +G ++ + V + P
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGP 333
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 83.6 bits (205), Expect = 3e-16
Identities = 108/418 (25%), Positives = 168/418 (40%), Gaps = 73/418 (17%)
Query: 22 PGLRLRLLLLLFSAAALIPTGDGQNLFTKDV-TVIEGEVATISCQVN-KSDDSVIQLL-- 77
P L LLLLL S P G+ L T DV TV+ G+ A + C S + V Q+
Sbjct: 12 PEAWLLLLLLLASFTGRCPAGE---LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWA 68
Query: 78 ----NPNRQTI------YFRDFRPLKDSRFQLLNFSSSEL--KVSLTNVSISDEGRYFCQ 125
Q + Y P + R + + L V L N +DEG Y C+
Sbjct: 69 RVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECR 128
Query: 126 LYTDPPQ--ESYTTITVLVPPRNLMIDIQKDTAVE---GEEIEVNCTAMASKPATTIRWF 180
+ T P ++ + VLVPP + + A+E G + +CTA S PA ++ W
Sbjct: 129 VSTFPAGSFQARLRLRVLVPP---LPSLNPGPALEEGQGLTLAASCTAEGS-PAPSVTW- 183
Query: 181 KGNTELKGKSEVEEW--SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLE 238
+TE+KG + + S VTS+ L + +G P+ C V HP + + + L
Sbjct: 184 --DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILH 241
Query: 239 VQYKPQVHIQ--MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGP 296
V + + ++ L + REG L+ C + G+P P W R+D +P + G
Sbjct: 242 VSFLAEASVRGLEDQNLWHIGREGAMLK--CLSEGQPPP-SYNWTRLDGPLPSGVRVDGD 298
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILT 356
L L +G Y C SN S + V DP
Sbjct: 299 TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP----------------------- 335
Query: 357 IITDSRAGEEGSIRAVD----HAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHE 410
+E S + VD V+ GV+A ++F +L ++++L + R K T +
Sbjct: 336 --------QEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 82.4 bits (202), Expect = 7e-16
Identities = 93/336 (27%), Positives = 136/336 (40%), Gaps = 27/336 (8%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
G L I ++K N T C +N +G ++ + V
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQV 329
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 79.7 bits (195), Expect = 5e-15
Identities = 62/261 (23%), Positives = 110/261 (42%), Gaps = 20/261 (7%)
Query: 104 SSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVE-GEEI 162
+ + + +T+ +SD+ Y CQ + +TVL+PP + ID ++ G
Sbjct: 80 AGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPH 139
Query: 163 EVNCTAMASKPATTIRWFKGNTELKG---KSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ C A +KPA TI WF+ T+ +G +E+ + T SQL++ D G
Sbjct: 140 NLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFT 199
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
C+ + A+ +T L+V + P V + + +EG+ + TC+A P+ +
Sbjct: 200 CRSMNEAIPSGKETSIELDVHHPPTVTLSIE---PQTVQEGERVVFTCQATANPEILGYR 256
Query: 280 WVR----VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
W + ++D + F CE N VG + ++ V+ P
Sbjct: 257 WAKGGFLIEDAHESRYETNVDYSFFTE-------PVSCEVHNKVGSTNVSTLVNVHFAPR 309
Query: 336 TI--PPPTTTTTTTTTTTTTI 354
+ P PTTT + T T +
Sbjct: 310 IVVDPKPTTTDIGSDVTLTCV 330
Score = 72.0 bits (175), Expect = 1e-12
Identities = 76/265 (28%), Positives = 113/265 (42%), Gaps = 30/265 (11%)
Query: 79 PNRQTIYFRDFRPLKDS--RFQLLNFSSSELKVS--LTNVSISDEGRYF-CQLYTDP-PQ 132
P I+FRD + + +LL E VS L N + D GR F C+ + P
Sbjct: 150 PAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPS 209
Query: 133 ESYTTITVLVP-PRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSE 191
T+I + V P + + I+ T EGE + C A A+ RW KG ++ E
Sbjct: 210 GKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHE 269
Query: 192 VEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTY 251
S+ V PV C+V + + N+ T + V + P++ +
Sbjct: 270 -----------SRYETNVDYSFFTEPVSCEVHNKVGSTNVST--LVNVHFAPRIVVD--- 313
Query: 252 PLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN-LFINNLNKTDNGT 310
P T G + LTC +G P P+ +TW + D M VLS N L + ++ + D GT
Sbjct: 314 PKPTTTDIGSDVTLTCVWVGNP-PLTLTWTKKDSNM----VLSNSNQLLLKSVTQADAGT 368
Query: 311 YRCEA-SNIVGKAHSDYMLYVYDPP 334
Y C A +G A + LYV PP
Sbjct: 369 YTCRAIVPRIGVAEREVPLYVNGPP 393
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 79.0 bits (193), Expect = 8e-15
Identities = 84/318 (26%), Positives = 138/318 (43%), Gaps = 42/318 (13%)
Query: 29 LLLLFSAAALIPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI- 84
L LLF +P G F K +VTV +GE AT+ C + D+ V ++ NR TI
Sbjct: 19 LRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTIL 75
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVP 143
Y + + D R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V
Sbjct: 76 YAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVS 135
Query: 144 PRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
P+ +++I D ++ EG I + C A +P T+ W + + G +E+ ++ +T
Sbjct: 136 PK--IVEISSDISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 203 SQLMLKVH---KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TR 258
+ D PV+ +V+ + V Y P + +G
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVP 234
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTY 311
G L CEA P W + D + + V + P L N+++ D G Y
Sbjct: 235 VGQKGTLQCEASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNY 293
Query: 312 RCEASNIVGKAHSDYMLY 329
C ASN +G ++ ML+
Sbjct: 294 TCVASNKLGHTNASIMLF 311
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 79.0 bits (193), Expect = 8e-15
Identities = 84/318 (26%), Positives = 138/318 (43%), Gaps = 42/318 (13%)
Query: 29 LLLLFSAAALIPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI- 84
L LLF +P G F K +VTV +GE AT+ C + D+ V ++ NR TI
Sbjct: 19 LRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTIL 75
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVP 143
Y + + D R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V
Sbjct: 76 YAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVS 135
Query: 144 PRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
P+ +++I D ++ EG I + C A +P T+ W + + G +E+ ++ +T
Sbjct: 136 PK--IVEISSDISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 203 SQLMLKVH---KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TR 258
+ D PV+ +V+ + V Y P + +G
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVP 234
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTY 311
G L CEA P W + D + + V + P L N+++ D G Y
Sbjct: 235 VGQKGTLQCEASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNY 293
Query: 312 RCEASNIVGKAHSDYMLY 329
C ASN +G ++ ML+
Sbjct: 294 TCVASNKLGHTNASIMLF 311
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 79.0 bits (193), Expect = 8e-15
Identities = 84/318 (26%), Positives = 138/318 (43%), Gaps = 42/318 (13%)
Query: 29 LLLLFSAAALIPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI- 84
L LLF +P G F K +VTV +GE AT+ C + D+ V ++ NR TI
Sbjct: 19 LRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTIL 75
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVP 143
Y + + D R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V
Sbjct: 76 YAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVS 135
Query: 144 PRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
P+ +++I D ++ EG I + C A +P T+ W + + G +E+ ++ +T
Sbjct: 136 PK--IVEISSDISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 203 SQLMLKVH---KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TR 258
+ D PV+ +V+ + V Y P + +G
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVP 234
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTY 311
G L CEA P W + D + + V + P L N+++ D G Y
Sbjct: 235 VGQKGTLQCEASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNY 293
Query: 312 RCEASNIVGKAHSDYMLY 329
C ASN +G ++ ML+
Sbjct: 294 TCVASNKLGHTNASIMLF 311
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 77.8 bits (190), Expect = 2e-14
Identities = 70/274 (25%), Positives = 121/274 (44%), Gaps = 27/274 (9%)
Query: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
Query: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
Query: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
Query: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301
V I+ + LQ + ++LTC+A P W ++ +P+ LF
Sbjct: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
Query: 302 N-LNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+N + GTY CEA+N +G + + + P
Sbjct: 304 GPINYSLAGTYICEATNPIGTRSGQVEVNITEKP 337
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 77.0 bits (188), Expect = 3e-14
Identities = 69/260 (26%), Positives = 117/260 (45%), Gaps = 27/260 (10%)
Query: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
Query: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
Query: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
Query: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301
V I+ + LQ + ++LTC+A P W ++ +P+ LF
Sbjct: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
Query: 302 N-LNKTDNGTYRCEASNIVG 320
+N + GTY CEA+N +G
Sbjct: 304 GPINYSLAGTYICEATNPIG 323
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
Length = 1331
Score = 76.3 bits (186), Expect = 5e-14
Identities = 38/70 (54%), Positives = 49/70 (70%), Gaps = 2/70 (2%)
Query: 375 AVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGG--QN 432
A+IGGV+AVV+F +LC L+ L RY RHKGTY T+EAKGA+ A AD AI+N + +
Sbjct: 1262 AIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTET 1321
Query: 433 NSEEKKEYFI 442
E KKE+ I
Sbjct: 1322 IDESKKEWLI 1331
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 75.5 bits (184), Expect = 9e-14
Identities = 67/282 (23%), Positives = 128/282 (45%), Gaps = 17/282 (6%)
Query: 84 IYFRDFRPL-KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-QESYTTITVL 141
++F+D + ++S +++S + + + V ++ G+Y CQ+ D QE + T++VL
Sbjct: 7524 VWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL 7583
Query: 142 VPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTV 201
P ++ + G+ + CT +A P + +WFK EL ++ + S V
Sbjct: 7584 -EPATIVEKPESIKVTTGDTCTLECT-VAGTPELSTKWFKDGKELTSDNKYKI-SFFNKV 7640
Query: 202 TSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGD 261
+ ++ V D GV +V++P + + + P + GL+ G
Sbjct: 7641 SGLKIINVAPSDSGVYSF-EVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS--GS 7697
Query: 262 ALELTCEAIGKPQPVMVTWVRVDDEMPQ----HAVLSGPN--LFINNLNKTDNGTYRCEA 315
++ + C+ G P P+ V+W +E+ L+ L +N L ++D+G Y C A
Sbjct: 7698 SVVMECKVYGSP-PISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIA 7756
Query: 316 SNIVGKAHSDYMLYVYDPPTTI--PPPTTTTTTTTTTTTTIL 355
+N+ G L V +PP+ + P P T T T T+I+
Sbjct: 7757 TNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIV 7798
Score = 73.2 bits (178), Expect = 5e-13
Identities = 76/308 (24%), Positives = 127/308 (41%), Gaps = 40/308 (12%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KD+ G T++C++N S Q ++RD L+D +F + +
Sbjct: 6182 KDIEQTVGLPVTLTCRLNGSAPI---------QVCWYRDGVLLRDDENLQTSFVDNVATL 6232
Query: 110 SLTNVSISDEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDT--AVEGEEIEVN 165
+ +S G+Y C ++P S +T P ++ DI+ + + GE +
Sbjct: 6233 KILQTDLSHSGQYSCSA-SNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFE 6291
Query: 166 CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ------LMLKVHKEDDGVPVI 219
C ++P I W K N E++ YT+T +LKV K D G
Sbjct: 6292 CHVTGAQPMR-ITWSKDNKEIRPGGN-------YTITCVGNTPHLRILKVGKGDSG-QYT 6342
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
CQ + G L V+ P+ ++ + ++G++++L C+ G P+ + V+
Sbjct: 6343 CQATNDV--GKDMCSAQLSVKEPPKFVKKLE--ASKVAKQGESIQLECKISGSPE-IKVS 6397
Query: 280 WVRVDDEMPQH------AVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDP 333
W R D E+ + + S L IN + D+G Y CEA N VG A L V P
Sbjct: 6398 WFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP 6457
Query: 334 PTTIPPPT 341
P P+
Sbjct: 6458 PVFTQKPS 6465
Score = 70.1 bits (170), Expect = 4e-12
Identities = 72/304 (23%), Positives = 125/304 (41%), Gaps = 31/304 (10%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
+ VI GE A C V + P R T + +D + ++ + + + +
Sbjct: 6280 IDVIAGESADFECHVTGAQ--------PMRIT-WSKDNKEIRPGGNYTITCVGNTPHLRI 6330
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTT-ITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
V D G+Y CQ D ++ + ++V PP+ + A +GE I++ C
Sbjct: 6331 LKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISG 6390
Query: 171 SKPATTIRWFKGNTELKGKSEVEEWS-DMYTVTSQLMLKVHKE--DDGVPVICQVEHPAV 227
S P + WF+ ++EL E W +M + S +L +++ +D IC+ +
Sbjct: 6391 S-PEIKVSWFRNDSELH-----ESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG 6444
Query: 228 TGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEM 287
+ T ++ P V Q P+ L +G + L CE G P P V WV+ ++
Sbjct: 6445 DASCSTALTVKA---PPVFTQKPSPVGAL--KGSDVILQCEISGTP-PFEVVWVKDRKQV 6498
Query: 288 PQHAVLS------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPT 341
+L I NL +D G Y C+A+N VG + +PP + +
Sbjct: 6499 RNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLS 6558
Query: 342 TTTT 345
T+T
Sbjct: 6559 DTST 6562
Score = 70.1 bits (170), Expect = 4e-12
Identities = 71/320 (22%), Positives = 135/320 (42%), Gaps = 31/320 (9%)
Query: 34 SAAALIPTGDGQN-----LFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRD 88
S+A LI T +G+N + V + GE A C V + + + +D
Sbjct: 8140 SSARLILT-EGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVS---------WAKD 8189
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT-ITV---LVPP 144
R ++ +++ + +++ V D G+Y C + ++S T + + L+PP
Sbjct: 8190 SREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPP 8249
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ EG ++ S+P T + W+K N E++ S E T+ Q
Sbjct: 8250 SFTKRLSETVEETEGNSFKLEGRVAGSQPIT-VAWYKNNIEIQPTSNCEITFKNNTLVLQ 8308
Query: 205 LMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE 264
+ K D G+ C+V + A + + ++ KP V Q P+ EG+ ++
Sbjct: 8309 VR-KAGMNDAGL-YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT--VSEGEYVQ 8364
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMP-----QHAVLSGPNLF-INNLNKTDNGTYRCEASNI 318
L+C G +P+ + W++ E+ + SG + + ++ K D+G Y C+ASN+
Sbjct: 8365 LSCHVQGS-EPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNV 8423
Query: 319 VGKAHSDYMLYVYDPPTTIP 338
G + + + D P P
Sbjct: 8424 AGSDTTKSKVTIKDKPAVAP 8443
Score = 65.9 bits (159), Expect = 7e-11
Identities = 70/311 (22%), Positives = 132/311 (42%), Gaps = 23/311 (7%)
Query: 62 ISCQVNKSDDSVIQLLNPNRQTI---YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISD 118
+S V + D + +Q+ + I +F+D + L ++ + + + + + D
Sbjct: 4586 VSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKD 4645
Query: 119 EGRYFCQLYTDPPQES----YTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPA 174
G Y ++ D + S + +++PP + ++K +++G I++ C S P
Sbjct: 4646 SGEYTFEVQNDVGRSSCKARINVLDLIIPP-SFTKKLKKMDSIKGSFIDLECIVAGSHPI 4704
Query: 175 TTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
+ I+WFK + E+ SE ++S + T+ L + + D C + A G+ Q
Sbjct: 4705 S-IQWFKDDQEISA-SEKYKFS-FHDNTAFLEISQLEGTDSGTYTCSATNKA--GHNQCS 4759
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
+L V+ P + P ++L +G P+ + W + + E+ A S
Sbjct: 4760 GHLTVKEPPYF---VEKPQSQDVNPNTRVQLKA-LVGGTAPMTIKWFKDNKELHSGAARS 4815
Query: 295 ------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTT 348
+L + TD+GTY C+ SN VG A S L+V +PP I P+
Sbjct: 4816 VWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRN 4875
Query: 349 TTTTTILTIIT 359
+TT IT
Sbjct: 4876 GQSTTFECQIT 4886
Score = 64.3 bits (155), Expect = 2e-10
Identities = 62/312 (19%), Positives = 122/312 (39%), Gaps = 22/312 (7%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
+TV+ GE A + + + +Q L + I ++S + F + +
Sbjct: 5619 LTVVAGEPAELQASIEGAQPIFVQWLKEKEEVI--------RESENIRITFVENVATLQF 5670
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMAS 171
++ G+Y CQ+ D +++ P ++ T GE + C +A
Sbjct: 5671 AKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECK-VAG 5729
Query: 172 KPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL 231
P ++ W+K +L S+ ++S ++S +L V ++D G QV++ +
Sbjct: 5730 TPELSVEWYKDG-KLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF-QVQNNVGKSSC 5787
Query: 232 QTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA 291
+ + P + G+ G + L C+ G P+ V W ++ A
Sbjct: 5788 TAVVDVSDRAVPPSFTRRLKNTGGVL--GASCILECKVAGS-SPISVAWFHEKTKIVSGA 5844
Query: 292 VLSGP------NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI--PPPTTT 343
L +N+L+ +D G Y C A+N+ G +L V +PP+ + P P
Sbjct: 5845 KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEV 5904
Query: 344 TTTTTTTTTTIL 355
T T+++
Sbjct: 5905 LPGKNVTFTSVI 5916
Score = 63.2 bits (152), Expect = 5e-10
Identities = 72/307 (23%), Positives = 127/307 (41%), Gaps = 35/307 (11%)
Query: 46 NLFTKD-VTVIE----------GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKD 94
NLF K+ T +E G+ ++C+V + P + +F + R +K+
Sbjct: 4292 NLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGT---------PPIKITWFANDREIKE 4342
Query: 95 SRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKD 154
S ++F S + LT+V I D G Y C+ + + ++I V+V K
Sbjct: 4343 SSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI-VIVKESPYFTKEFKP 4401
Query: 155 TAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDD 214
V E + +A P I WFK NT L+ + + + + V+ Q+ LK D
Sbjct: 4402 IEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI-LKFVAADA 4460
Query: 215 GVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQ 274
G C+V + + + L I+ T L+G T A + T +
Sbjct: 4461 G-EYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTA---AFQATLKG---SL 4513
Query: 275 PVMVTWVRVDDEMPQHAVL------SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYML 328
P+ VTW++ DE+ + + + +L+++ + +G Y C+A N G +L
Sbjct: 4514 PITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 4573
Query: 329 YVYDPPT 335
V +P T
Sbjct: 4574 SVKEPAT 4580
Score = 63.2 bits (152), Expect = 5e-10
Identities = 65/278 (23%), Positives = 117/278 (42%), Gaps = 20/278 (7%)
Query: 79 PNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTI 138
P + ++++D R L+ S+ + + + + NV SD G Y C+ + ++
Sbjct: 5544 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCT 5603
Query: 139 TVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDM 198
L P + + T V GE E+ + ++P ++W K E+ +SE + +
Sbjct: 5604 VKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQP-IFVQWLKEKEEVIRESENIRITFV 5662
Query: 199 YTVTSQLMLKVHKEDDGVPVICQVEHP-AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT 257
V + K + G ICQ+++ + N+ T LE P V ++ P+
Sbjct: 5663 ENVATLQFAKAEPANAG-KYICQIKNDGGMRENMATLMVLE----PAVIVEKAGPM--TV 5715
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEM---PQHAVLSGPN----LFINNLNKTDNGT 310
G+ L C+ G P+ + V W + D ++ Q S N L I ++ + D GT
Sbjct: 5716 TVGETCTLECKVAGTPE-LSVEWYK-DGKLLTSSQKHKFSFYNKISSLRILSVERQDAGT 5773
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTT 348
Y + N VGK+ ++ V D +PP T T
Sbjct: 5774 YTFQVQNNVGKSSCTAVVDVSD--RAVPPSFTRRLKNT 5809
Score = 62.4 bits (150), Expect = 8e-10
Identities = 61/265 (23%), Positives = 111/265 (41%), Gaps = 28/265 (10%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+FR R L + F + ++ L N+ IS G Y C + + Q S TT + P
Sbjct: 5926 WFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP 5985
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ + + G+ I + T + P ++ W K + E ++ T
Sbjct: 5986 AAFLKRLSDHSVEPGKSIILESTYTGTLP-ISVTWKKDGFNI----TTSEKCNIVTTEKT 6040
Query: 205 LMLKV--HKEDDGVPVICQVEHPA---VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTRE 259
+L++ + D C++E+ A V G L + +P + PL+
Sbjct: 6041 CILEILNSTKRDAGQYSCEIENEAGRDVCGALVS------TLEPPYFVTELEPLEAAV-- 6092
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEM---PQHAVLSGPN---LFINNLNKTDNGTYRC 313
GD++ L C+ G P+ + V+W + D ++ P++ N L N +N D+G Y C
Sbjct: 6093 GDSVSLQCQVAGTPE-ITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 6151
Query: 314 EASNIVGKAHSDYMLYVYD---PPT 335
+A N +G A S + + + PP+
Sbjct: 6152 KAENSIGTASSKTVFRIQERQLPPS 6176
Score = 61.6 bits (148), Expect = 1e-09
Identities = 66/310 (21%), Positives = 116/310 (37%), Gaps = 24/310 (7%)
Query: 54 VIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTN 113
++ GE A + C++ S P Q +F++ + L +S + F +SE + +T+
Sbjct: 3749 MLPGESARLHCKLKGS---------PVIQVTWFKNNKELSESNTVRMYFVNSEAILDITD 3799
Query: 114 VSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKP 173
V + D G Y C+ D +S +T V+ P + + ++ V G + C + P
Sbjct: 3800 VKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP 3859
Query: 174 ATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQT 233
I WFK +++ + +S V ++ + D G G + T
Sbjct: 3860 -FEISWFKDKKQIRSSKKYRLFSQKSLVCLEI-FSFNSADVGEYECVVANEVGKCGCMAT 3917
Query: 234 QRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW------VRVDDEM 287
E P ++ L L + L+ A+ +P+ VTW +R D ++
Sbjct: 3918 HLLKE----PPTFVKKVDDLIALGGQTVTLQ---AAVRGSEPISVTWMKGQEVIREDGKI 3970
Query: 288 PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTT 347
L I ++ + G Y C A N G S L V +P I T
Sbjct: 3971 KMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTA 4030
Query: 348 TTTTTTILTI 357
T T+
Sbjct: 4031 GDPATLEYTV 4040
Score = 61.2 bits (147), Expect = 2e-09
Identities = 66/321 (20%), Positives = 123/321 (38%), Gaps = 56/321 (17%)
Query: 48 FTKDVTVIE---GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSS 104
FTK +T ++ G + C+V+ S Q +F+D + + S L
Sbjct: 5239 FTKKLTKMDKVLGSSIHMECKVSGSLPISAQ---------WFKDGKEISTSAKYRLVCHE 5289
Query: 105 SELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEV 164
+ + + N+ + D Y C++ ++ + I + P + ++ + A+ +E
Sbjct: 5290 RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEF 5349
Query: 165 NCTAMASKPATTIRWFKGNTELK-------GKSEVEEWSDMYTV----TSQLMLKVHKE- 212
+ P I+WFK + EL G + ++Y+V T Q V +
Sbjct: 5350 K-AILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDV 5408
Query: 213 --DDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAI 270
D ++ E P L+ + + + GD+ L C+
Sbjct: 5409 GSDSCTTMLLVTEPPKFVKKLEASK--------------------IVKAGDSSRLECKIA 5448
Query: 271 GKPQPVMVTWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHS 324
G P+ + V W R + E+P + S + +NNL+ D+G + CEA N G
Sbjct: 5449 GSPE-IRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSC 5507
Query: 325 DYMLYVYDPP--TTIPPPTTT 343
+ V +PP ++ PP T
Sbjct: 5508 STKVIVKEPPVFSSFPPIVET 5528
Score = 60.8 bits (146), Expect = 2e-09
Identities = 60/257 (23%), Positives = 114/257 (44%), Gaps = 16/257 (6%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+F+D L + S ++L +V S G+Y C + D +S TT+ ++ P
Sbjct: 5363 WFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP 5422
Query: 145 RNLMIDIQKDTAVE-GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTS 203
+ ++ V+ G+ + C +A P + WF+ EL S+ + + +V
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLEC-KIAGSPEIRVVWFRNEHELPA-SDKYRMTFIDSVAV 5480
Query: 204 QLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDAL 263
M + ED G IC+ ++PA + + T+ ++ +P V ++P T + +
Sbjct: 5481 IQMNNLSTEDSG-DFICEAQNPAGSTSCSTKVIVK---EPPVF--SSFPPIVETLKNAEV 5534
Query: 264 ELTCEAIGKPQPVMVTWVRVDDEM---PQHAVLS---GPNLFINNLNKTDNGTYRCEASN 317
L CE G P P V W + ++ ++ + S ++ I N++ +D G Y C+A N
Sbjct: 5535 SLECELSGTP-PFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 5593
Query: 318 IVGKAHSDYMLYVYDPP 334
VG + + +PP
Sbjct: 5594 EVGSDTCVCTVKLKEPP 5610
Score = 59.3 bits (142), Expect = 7e-09
Identities = 52/255 (20%), Positives = 103/255 (40%), Gaps = 22/255 (8%)
Query: 92 LKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDI 151
+++S ++F + + L + S+ G+Y CQ+ D + + ++ P ++
Sbjct: 6592 IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP 6651
Query: 152 QKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHK 211
+ T G + C + P + +WFK EL S+ + + V S +
Sbjct: 6652 EPMTVTTGNPFALECVVTGT-PELSAKWFKDGRELSADSK-HHITFINKVASLKIPCAEM 6709
Query: 212 EDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIG 271
D G+ +V++ N ++ + P I+ + + G ++ L C G
Sbjct: 6710 SDKGLYSF-EVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAIL--GASVVLECRVSG 6766
Query: 272 KPQPVMVTWVRVDDEMPQHAVLSGPN-----------LFINNLNKTDNGTYRCEASNIVG 320
P+ V W + +E ++SGP L ++ L +D G Y C A+N+ G
Sbjct: 6767 SA-PISVGWFQDGNE-----IVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAG 6820
Query: 321 KAHSDYMLYVYDPPT 335
+L V +PP+
Sbjct: 6821 SDECSAVLTVQEPPS 6835
Score = 58.5 bits (140), Expect = 1e-08
Identities = 75/297 (25%), Positives = 121/297 (40%), Gaps = 32/297 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDV G C++N S+ Q +++D LKD +F + +
Sbjct: 7123 KDVHETLGFPVAFECRINGSEPL---------QVSWYKDGVLLKDDANLQTSFVHNVATL 7173
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVL----VPPRNLMIDIQKDTAVEGEEIEVN 165
+ S G+Y C S + +L VPP + + D A+ GE
Sbjct: 7174 QILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLAL-GESGTFK 7232
Query: 166 CTAMASKPATTIRWFKGNTELK--GKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVE 223
C + P I W K N E++ G ++ + T+T +LKV K D G C
Sbjct: 7233 CHVTGTAPIK-ITWAKDNREIRPGGNYKMTLVENTATLT---VLKVGKGDAG-QYTCYAS 7287
Query: 224 HPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRV 283
+ + G L VQ P+ I+ P + + ++ + C+ G P+ + V W +
Sbjct: 7288 N--IAGKDSCSAQLGVQEPPRF-IKKLEPSR-IVKQDEFTRYECKIGGSPE-IKVLWYKD 7342
Query: 284 DDEMPQHA------VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+ E+ + + V S L ++NL+ D+G Y CEA N G A S L V +PP
Sbjct: 7343 ETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 7399
Score = 56.6 bits (135), Expect = 4e-08
Identities = 64/299 (21%), Positives = 121/299 (40%), Gaps = 32/299 (10%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
V + GE AT+ C+V+ + P + ++++ L+ + + F ++ + +
Sbjct: 7029 VEAVIGEPATLQCKVDGT---------PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 7079
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTTITVL----VPP--RNLMIDIQKDTAVEGEEIEVN 165
V SD G Y C+ + + + V+ +PP + D+ + G +
Sbjct: 7080 NKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETL---GFPVAFE 7136
Query: 166 CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHP 225
C S+P + W+K LK + ++ S ++ V + +L+ + G C +P
Sbjct: 7137 CRINGSEPLQ-VSWYKDGVLLKDDANLQT-SFVHNVATLQILQTDQSHIG-QYNCSASNP 7193
Query: 226 AVTGNLQTQRYL-EVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
T + + L E + P ++ P+ G++ C G P+ +TW + +
Sbjct: 7194 LGTASSSAKLILSEHEVPPFFDLK---PVSVDLALGESGTFKCHVTGTA-PIKITWAKDN 7249
Query: 285 DEM------PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
E+ V + L + + K D G Y C ASNI GK L V +PP I
Sbjct: 7250 REIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFI 7308
Score = 56.2 bits (134), Expect = 6e-08
Identities = 60/280 (21%), Positives = 111/280 (39%), Gaps = 16/280 (5%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDP-PQESYTTITVLVP 143
+F+D + L + + + + L +D G Y CQL D S T+ V P
Sbjct: 4801 WFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP 4860
Query: 144 PRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTS 203
P+ + G+ C + P + W+ E+ + +
Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQ-ITGTPKIRVSWYLDGNEITAIQK--HGISFIDGLA 4917
Query: 204 QLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDAL 263
+ + ++ +C+ + A T + + L+V+ +P I+ P++ + + D +
Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIE--LKVK-EPPTFIRELKPVE-VVKYSD-V 4972
Query: 264 ELTCEAIGKPQPVMVTWVRVDDEMPQHAV------LSGPNLFINNLNKTDNGTYRCEASN 317
EL CE G P P VTW++ + E+ +S NL I + +D G Y+C SN
Sbjct: 4973 ELECEVTGTP-PFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN 5031
Query: 318 IVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTI 357
G + + +PP+ I TTT ++ T T+
Sbjct: 5032 EGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTV 5071
Score = 56.2 bits (134), Expect = 6e-08
Identities = 61/266 (22%), Positives = 110/266 (41%), Gaps = 20/266 (7%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+++D R L+ + + + + + NV +D G Y C+ D ++ L P
Sbjct: 7432 WYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAP 7491
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ + + V G+E+++ T ++P + + WFK E+ +S+ S + +
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV-WFKDKGEIVRESDNIWISYSENIATL 7550
Query: 205 LMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE 264
+V + G CQ+++ A G + L V +P ++ ++ T GD
Sbjct: 7551 QFSRVEPANAG-KYTCQIKNDA--GMQECFATLSV-LEPATIVEKPESIKVTT--GDTCT 7604
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMPQ--------HAVLSGPNLFINNLNKTDNGTYRCEAS 316
L C G P+ + W + E+ +SG L I N+ +D+G Y E
Sbjct: 7605 LECTVAGTPE-LSTKWFKDGKELTSDNKYKISFFNKVSG--LKIINVAPSDSGVYSFEVQ 7661
Query: 317 NIVGKAHSDYMLYVYDPPTTIPPPTT 342
N VGK L V D T+PP T
Sbjct: 7662 NPVGKDSCTASLQVSD--RTVPPSFT 7685
Score = 55.5 bits (132), Expect = 1e-07
Identities = 66/315 (20%), Positives = 122/315 (38%), Gaps = 36/315 (11%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
V V G+ A++ CQ+ + P +++ L+ + ++F ++ +
Sbjct: 7970 VKVSVGDSASLQCQLAGT---------PEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF 8020
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTTITVL----VPP--RNLMIDIQKDTAVEGEEIEVN 165
V I+D G Y C+ + S +T + +PP + D+Q+ G + +
Sbjct: 8021 NQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETV---GLPVVFD 8077
Query: 166 CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGV--PVICQVE 223
C S+P ++ W+K LK V+ T T L + K D + C
Sbjct: 8078 CAISGSEP-ISVSWYKDGKPLKDSPNVQTSFLDNTAT----LNIFKTDRSLAGQYSCTAT 8132
Query: 224 HPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRV 283
+P + + + L P P+ + G++ + C G QP+ V+W +
Sbjct: 8133 NPIGSASSSARLILTEGKNPPFFDIRLAPVDAVV--GESADFECHVTG-TQPIKVSWAKD 8189
Query: 284 DDEMPQHA------VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
E+ + + +L + ++K D+G Y C A N VGK L + + I
Sbjct: 8190 SREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE--RLI 8247
Query: 338 PPPTTTTTTTTTTTT 352
PP T + T T
Sbjct: 8248 PPSFTKRLSETVEET 8262
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/293 (21%), Positives = 117/293 (39%), Gaps = 27/293 (9%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+ + V G+ T+ C V + P T +F+D + L ++F + +
Sbjct: 7593 ESIKVTTGDTCTLECTVAGT---------PELSTKWFKDGKELTSDNKYKISFFNKVSGL 7643
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEVNC 166
+ NV+ SD G Y ++ ++S T ++ P + +++ + G + + C
Sbjct: 7644 KIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMEC 7703
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
S P ++ WF E+ + + + + T L + + +E D C + A
Sbjct: 7704 KVYGS-PPISVSWFHEGNEISSGRKYQ--TTLTDNTCALTVNMLEESDSGDYTCIATNMA 7760
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
G+ + L V+ +P +Q P+ LT G + T G P P V+W + E
Sbjct: 7761 --GSDECSAPLTVR-EPPSFVQKPDPMDVLT--GTNVTFTSIVKGTP-PFSVSWFKGSSE 7814
Query: 287 MPQ------HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDP 333
+ S L + +++ + +G Y C SN GKA LY+ P
Sbjct: 7815 LVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAP 7867
Score = 54.7 bits (130), Expect = 2e-07
Identities = 56/291 (19%), Positives = 114/291 (39%), Gaps = 24/291 (8%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT 137
+P + ++++D +++S ++F S + + N+S+ D G Y C+ + S +T
Sbjct: 7332 SPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391
Query: 138 ITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSD 197
+ P ++G ++ + C + P + W+K EL+ + + S+
Sbjct: 7392 SLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFH-VSWYKDKRELRSGKKYKIMSE 7450
Query: 198 MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT 257
+ +TS +L V D G C+ + + L+ P ++ + +
Sbjct: 7451 NF-LTSIHILNVDAADIG-EYQCKATNDVGSDTCVGSIALKA---PPRFVKKLSDISTVV 7505
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN-----------NLNKT 306
+ L+ T E +P+ V W + E+ V N++I+ +
Sbjct: 7506 GKEVQLQTTIEGA---EPISVVWFKDKGEI----VRESDNIWISYSENIATLQFSRVEPA 7558
Query: 307 DNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTI 357
+ G Y C+ N G L V +P T + P + TT T T T+
Sbjct: 7559 NAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTV 7609
Score = 54.3 bits (129), Expect = 2e-07
Identities = 54/258 (20%), Positives = 105/258 (40%), Gaps = 16/258 (6%)
Query: 100 LNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEG 159
+ F ++ + L+ + + +G+Y CQ D + + + + P + + +G
Sbjct: 4534 MTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQG 4593
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ + +K T +WFK EL S+ + S TV+ ++ K+D G
Sbjct: 4594 DPATLQVKFSGTKEITA-KWFKDGQELTLGSKY-KISVTDTVSILKIISTEKKDSG-EYT 4650
Query: 220 CQVEHPAVTGNLQTQ-RYLEVQYKPQVHIQMTYPLQGL-TREGDALELTCEAIGKPQPVM 277
+V++ + + + L++ P T L+ + + +G ++L C G P+
Sbjct: 4651 FEVQNDVGRSSCKARINVLDLIIPP----SFTKKLKKMDSIKGSFIDLECIVAGS-HPIS 4705
Query: 278 VTWVRVDDEMPQHAVL------SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
+ W + D E+ + L I+ L TD+GTY C A+N G L V
Sbjct: 4706 IQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765
Query: 332 DPPTTIPPPTTTTTTTTT 349
+PP + P + T
Sbjct: 4766 EPPYFVEKPQSQDVNPNT 4783
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/270 (20%), Positives = 105/270 (38%), Gaps = 14/270 (5%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT 137
+P + +D + L + ++F S + + +V GRY CQ + E
Sbjct: 5074 SPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYA 5133
Query: 138 ITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSD 197
++ P ++ + E + + + C +A P ++W K ++ S S
Sbjct: 5134 FLLVQEPAQIVEKAKSVDVTEKDPMTLECV-VAGTPELKVKWLKDGKQIV-PSRYFSMSF 5191
Query: 198 MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ-RYLEVQYKPQVHIQMTYPLQGL 256
V S + V K+D G +VE+ + + R L+ P ++T + L
Sbjct: 5192 ENNVASFRIQSVMKQDSGQYTF-KVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVL 5250
Query: 257 TREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS------GPNLFINNLNKTDNGT 310
G ++ + C+ G P+ W + E+ A +L +NNL D
Sbjct: 5251 ---GSSIHMECKVSGS-LPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN 5306
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPPP 340
Y C+ SN+ G +L V +PP+ + P
Sbjct: 5307 YTCKVSNVAGDDACSGILTVKEPPSFLVKP 5336
Score = 52.8 bits (125), Expect = 6e-07
Identities = 69/300 (23%), Positives = 122/300 (40%), Gaps = 51/300 (17%)
Query: 65 QVNKSDDSVIQLL---NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGR 121
QV D + ++ P + +++D RPL S+ ++F ++ ++ + + D G+
Sbjct: 4027 QVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQ 4086
Query: 122 YFCQLYTDPPQESY-TTITVL---------VPPRNLMIDIQKDTAVEGEEIEVNCTAMAS 171
Y ++ + S TT TVL P RN+ D+ V G ++C S
Sbjct: 4087 YTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNV------DSVVNGT-CRLDCKIAGS 4139
Query: 172 KPATTIRWFKGNTELKGKSEVEEWSDMYTVT------SQLMLKVHKEDDGVPVICQVEHP 225
P + WFK E+ SD Y + S +++V D G C+ +
Sbjct: 4140 LPMR-VSWFKDGKEIAA-------SDRYRIAFVEGTASLEIIRVDMNDAG-NFTCRATNS 4190
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDD 285
G+ + L VQ P +T P G A+ L G P+ + W + +
Sbjct: 4191 V--GSKDSSGALIVQEPPSF---VTKPGSKDVLPGSAVCLKSTFQGST-PLTIRWFKGNK 4244
Query: 286 EM--------PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
E+ + A+ S L++ + +D+GTY C+ SN+ G L+V +P T +
Sbjct: 4245 ELVSGGSCYITKEALESSLELYL--VKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFV 4302
Score = 50.1 bits (118), Expect = 4e-06
Identities = 70/307 (22%), Positives = 119/307 (38%), Gaps = 34/307 (11%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
K V V++ + C+V + + L NR+ ++ S+ L S +
Sbjct: 4962 KPVEVVKYSDVELECEVTGTPPFEVTWLKNNRE---------IRSSKKYTLTDRVSVFNL 5012
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+T SD G Y C + + S +T L P + + I+ T V T +
Sbjct: 5013 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQST-V 5071
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYT--VTSQLMLKVHKEDDGVP--VICQVEHP 225
A P +I W LK ++E ++Y V S L++ D+G CQ ++
Sbjct: 5072 AGSPPISITW------LKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNE 5125
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDD 285
+G + +L VQ Q+ ++ + E D + L C G P+ + V W++
Sbjct: 5126 --SGVERCYAFLLVQEPAQI-VEKAKSVD--VTEKDPMTLECVVAGTPE-LKVKWLKDGK 5179
Query: 286 EMPQHAVLS------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPP 339
++ S + I ++ K D+G Y + N G + D L V D IPP
Sbjct: 5180 QIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD--QNIPP 5237
Query: 340 PTTTTTT 346
T T
Sbjct: 5238 SFTKKLT 5244
Score = 50.1 bits (118), Expect = 4e-06
Identities = 66/317 (20%), Positives = 123/317 (38%), Gaps = 36/317 (11%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+DV G C ++ S+ + +++D +PLKDS +F + +
Sbjct: 8064 RDVQETVGLPVVFDCAISGSEPISVS---------WYKDGKPLKDSPNVQTSFLDNTATL 8114
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRN---LMIDIQKDTAVEGEEIEVNC 166
++ S G+Y C S + +L +N I + AV GE + C
Sbjct: 8115 NIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFEC 8174
Query: 167 TAMASKPATTIRWFKGNTELK--GKSEVEEWSDMYTVTSQLMLKVHKEDDG---VPVICQ 221
++P + W K + E++ GK ++ + +T +LKV K D G + +
Sbjct: 8175 HVTGTQP-IKVSWAKDSREIRSGGKYQISYLENSAHLT---VLKVDKGDSGQYTCYAVNE 8230
Query: 222 VEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWV 281
V + T L + L P +++ ++ EG++ +L G QP+ V W
Sbjct: 8231 VGKDSCTAQLNIKERL---IPPSFTKRLSETVE--ETEGNSFKLEGRVAGS-QPITVAWY 8284
Query: 282 R--VDDEMPQHAVLSGPN----LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
+ ++ + + ++ N L + D G Y C+ SN G A + + +P
Sbjct: 8285 KNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPK- 8343
Query: 336 TIPPPTTTTTTTTTTTT 352
PP T T +
Sbjct: 8344 --KPPVFDQHLTPVTVS 8358
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/253 (23%), Positives = 101/253 (39%), Gaps = 28/253 (11%)
Query: 100 LNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAV-- 157
+ F ++ L + + ++D G Y C++ D T+ V+ P+ + Q T V
Sbjct: 8298 ITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTV 8357
Query: 158 -EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGV 216
EGE ++++C S+P I+W K E+K + T+ L L+ + D
Sbjct: 8358 SEGEYVQLSCHVQGSEPIR-IQWLKAGREIKPSDRCS--FSFASGTAVLELRDVAKADSG 8414
Query: 217 PVICQVEHPAVTGNLQTQRYLEVQYKPQVH------------IQMTYPLQGLTREGDALE 264
+C+ + V G+ T+ + ++ KP V ++ P E
Sbjct: 8415 DYVCKASN--VAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTAT 8472
Query: 265 LTCEAIGKPQPVMVTWVRVD-DEMPQ------HAVLSGPNLFINNLNKTDNGTYRCEASN 317
+ G P P V W + ++ Q H L I + KTD+G YRC A N
Sbjct: 8473 FIAKVGGDPIP-NVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFN 8531
Query: 318 IVGKAHSDYMLYV 330
G+ S+ L V
Sbjct: 8532 EHGEIESNVNLQV 8544
Score = 49.7 bits (117), Expect = 5e-06
Identities = 63/291 (21%), Positives = 118/291 (40%), Gaps = 32/291 (10%)
Query: 57 GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSI 116
G+ ++ CQV + + + + + RP + R F+++ + V+I
Sbjct: 6093 GDSVSLQCQVAGTPEITVSWYKGDTK------LRPTPEYRTY---FTNNVATLVFNKVNI 6143
Query: 117 SDEGRYFCQLYTDPPQESYTTITVL----VPPR--NLMIDIQKDTAVEGEEIEVNCTAMA 170
+D G Y C+ S T+ + +PP + DI++ G + + C
Sbjct: 6144 NDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTV---GLPVTLTCRLNG 6200
Query: 171 SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGN 230
S P + W++ L+ ++ S + V + +L+ G C +P T +
Sbjct: 6201 SAPIQ-VCWYRDGVLLRDDENLQT-SFVDNVATLKILQTDLSHSG-QYSCSASNPLGTAS 6257
Query: 231 LQTQRYL-EVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ 289
+ E + P I+ P+ G++ + C G QP+ +TW + + E+
Sbjct: 6258 SSARLTAREPKKSPFFDIK---PVSIDVIAGESADFECHVTGA-QPMRITWSKDNKEIRP 6313
Query: 290 HA------VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
V + P+L I + K D+G Y C+A+N VGK L V +PP
Sbjct: 6314 GGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPP 6364
Score = 49.7 bits (117), Expect = 5e-06
Identities = 51/269 (18%), Positives = 106/269 (39%), Gaps = 22/269 (8%)
Query: 100 LNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEG 159
++ S ++ L +V S G Y C + + + S TT + P + + + +G
Sbjct: 7823 VSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKG 7882
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKE--DDGVP 217
+ + + T P ++ W K + ++ T +L++ +D
Sbjct: 7883 KPLILEGT-FTGTPPISVTWKKNGINVTPSQRC----NITTTEKSAILEIPSSTVEDAGQ 7937
Query: 218 VICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVM 277
C +E+ + + Q + +P ++ P++ GD+ L C+ G P+ +
Sbjct: 7938 YNCYIENASGKDSCSAQILI---LEPPYFVKQLEPVK--VSVGDSASLQCQLAGTPE-IG 7991
Query: 278 VTWVRVDDEM------PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
V+W + D ++ H + L N ++ D+G Y C+A N VG+ + L V
Sbjct: 7992 VSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Query: 332 DPPTTIPPPTTTTTTTTTTTTTILTIITD 360
+ PP+ + T L ++ D
Sbjct: 8052 EQKL---PPSFSRQLRDVQETVGLPVVFD 8077
Score = 49.3 bits (116), Expect = 7e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 12/127 (9%)
Query: 237 LEVQYKPQVHIQMTYPLQGLT-REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSG 295
++ Q P++ + + L GLT + G +EL GKP+P +TW + D + Q ++
Sbjct: 13682 VDTQEAPEIFLDVKL-LAGLTVKAGTKIELPATVTGKPEP-KITWTKADMILKQDKRITI 13739
Query: 296 PNL------FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTT 349
N+ I + ++D GTY EA N+ G+A + + V D P PP T T
Sbjct: 13740 ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKP---GPPAAFDITDVT 13796
Query: 350 TTTTILT 356
+ +LT
Sbjct: 13797 NESCLLT 13803
Score = 48.5 bits (114), Expect = 1e-05
Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 27/190 (14%)
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
GE +++C + +P I+W++ EL + + SD T T +M + +ED+GV
Sbjct: 30547 GEAAQLSCQ-IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTE-EQEDEGVYT 30604
Query: 219 ICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQG--LTREGDALELTCEAIGKPQPV 276
G ++T L +Q PQ H YPL+ G L L IG+P P
Sbjct: 30605 CIATNE---VGEVETSSKLLLQATPQFH--PGYPLKEKYYGAVGSTLRLHVMYIGRPVPA 30659
Query: 277 MVTWVRVDDEMPQHAVLSGPNLFINNLN------------KTDNGTYRCEASNIVGKAHS 324
M TW Q + + N+ I N KT G Y+ + SN+ G +
Sbjct: 30660 M-TWFH-----GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDA 30713
Query: 325 DYMLYVYDPP 334
+ + D P
Sbjct: 30714 ILDVEIQDKP 30723
Score = 47.0 bits (110), Expect = 3e-05
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 5/100 (5%)
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN----LFINNLNKTDNGTYRC 313
R G +L L G+P PV +TW + ++ A++ L ++ +N+ D G Y
Sbjct: 29459 RAGASLRLMVSVSGRPPPV-ITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTI 29517
Query: 314 EASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTT 353
EA N GK + ++ VYD P P + + T T
Sbjct: 29518 EAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTIT 29557
Score = 45.8 bits (107), Expect = 8e-05
Identities = 54/282 (19%), Positives = 105/282 (37%), Gaps = 16/282 (5%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT 137
+P + ++FR+ L S + F S + + N+S D G + C+ S +T
Sbjct: 5450 SPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCST 5509
Query: 138 ITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSD 197
++ P ++ E+ + C ++ P + W+K +L+ + + S
Sbjct: 5510 KVIVKEPPVFSSFPPIVETLKNAEVSLEC-ELSGTPPFEVVWYKDKRQLRSSKKYKIASK 5568
Query: 198 MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT 257
+ TS +L V D G C+ ++ + L+ +P + L +
Sbjct: 5569 NFH-TSIHILNVDTSDIG-EYHCKAQNEVGSDTCVCTVKLK---EPPRFVSKLNSLTVVA 5623
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA-------VLSGPNLFINNLNKTDNGT 310
E L+ + E QP+ V W++ +E+ + + V + L + G
Sbjct: 5624 GEPAELQASIEG---AQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGK 5680
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTT 352
Y C+ N G + L V +P + T T T T
Sbjct: 5681 YICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCT 5722
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 15/137 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+DVT+ EG+ T++CQ + PN ++ +FR+ R LK K+
Sbjct: 8752 QDVTLKEGQTCTMTCQFSV----------PNVKSEWFRNGRILKPQGRHKTEVEHKVHKL 8801
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
++ +V D+G+Y C+ Y D E+ + + P IQ E + C
Sbjct: 8802 TIADVRAEDQGQYTCK-YED--LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECE-- 8856
Query: 170 ASKPATTIRWFKGNTEL 186
S + W+KG TEL
Sbjct: 8857 VSFDDAIVTWYKGPTEL 8873
Score = 44.7 bits (104), Expect = 2e-04
Identities = 45/202 (22%), Positives = 79/202 (39%), Gaps = 22/202 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+D TV EGE AT C +L + ++F++ L SR L++ K+
Sbjct: 11581 EDQTVKEGETATFVC----------ELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKL 11630
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ V++ D + Q+ S + VL + + TAVE +EI + C
Sbjct: 11631 EMKEVTLDDISQIKAQV---KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS 11687
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKED--DGVPVICQVEHPAV 227
P ++WFK E+ + +D + +LK+ K D D +C
Sbjct: 11688 KDVP---VKWFKDGEEIVPSPKYSIKAD----GLRRILKIKKADLKDKGEYVCDCGTDKT 11740
Query: 228 TGNLQTQRYLEVQYKPQVHIQM 249
N+ + L KP +++
Sbjct: 11741 KANVTVEARLIKVEKPLYGVEV 11762
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/138 (26%), Positives = 59/138 (42%), Gaps = 11/138 (7%)
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
EH V G + + LE P + + + R G +L L G+P P V W +
Sbjct: 22923 EHADVPGPIIVEEKLEA---PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPE-VKWGK 22978
Query: 283 VDDEMPQHAVL----SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP 338
VD E+ A++ S +L ++N+N+ D+G Y N G + + V D P+
Sbjct: 22979 VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPS--- 23035
Query: 339 PPTTTTTTTTTTTTTILT 356
PP T T + +T
Sbjct: 23036 PPVNLKVTEITKDSVSIT 23053
Score = 43.5 bits (101), Expect = 4e-04
Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 10/105 (9%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ------HAVLSGP 296
P++ ++ Y + + GD +++ +G+P+P VTW + D + Q +
Sbjct: 21063 PELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPT-VTWKKGDQILKQTQRVNFETTATST 21121
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPT 341
L IN ++D+G Y A NIVG+ + V+D P PPT
Sbjct: 21122 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP---GPPT 21163
Score = 42.7 bits (99), Expect = 7e-04
Identities = 59/295 (20%), Positives = 105/295 (35%), Gaps = 27/295 (9%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
+TV G + C V + P +F+D R L + F + + +
Sbjct: 6654 MTVTTGNPFALECVVTGT---------PELSAKWFKDGRELSADSKHHITFINKVASLKI 6704
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEVNCTA 168
+SD+G Y ++ + + T ++ + P + + ++ A+ G + + C
Sbjct: 6705 PCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRV 6764
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVT 228
S P + + WF+ E+ + + T L L + D G+ V
Sbjct: 6765 SGSAPIS-VGWFQDGNEIVSGPKCQSSFSENVCTLNLSL-LEPSDTGIYTCVAAN---VA 6819
Query: 229 GNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEM- 287
G+ + L VQ P P G +L T G P P V W + E+
Sbjct: 6820 GSDECSAVLTVQEPPSFE---QTPDSVEVLPGMSLTFTSVIRGTP-PFKVKWFKGSRELV 6875
Query: 288 PQHAVLSGPNLFINNLN-----KTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
P + F+ L ++G Y C +N G A L+V +P T +
Sbjct: 6876 PGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFV 6930
Score = 42.7 bits (99), Expect = 7e-04
Identities = 72/324 (22%), Positives = 118/324 (36%), Gaps = 41/324 (12%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDVTV GE AT C+++ D V L + L+ S + +
Sbjct: 12203 KDVTVTAGETATFDCELSYEDIPVEWYLKGKK----------LEPSDKVVPRSEGKVHTL 12252
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+L +V + D G QL T +++ + V PP ++ T EG + C
Sbjct: 12253 TLRDVKLEDAGE--VQL-TAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECE-- 12307
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
S+ ++WFK TE+ + E +D +L++ +D C + +
Sbjct: 12308 VSRENAKVKWFKNGTEILKSKKYEIVAD--GRVRKLVIHDCTPEDIKTYTCDAKDFKTSC 12365
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGL-TREGDALELTCEAIGKPQPVMVTWVRVDDEM- 287
NL H++ PL L RE + CE + V W + E+
Sbjct: 12366 NLNV---------VPPHVEFLRPLTDLQVREKEMARFECEL--SRENAKVKWFKDGAEIK 12414
Query: 288 --PQHAVLSGPNLFINNLNK---TDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTT 342
++ ++S + I +NK D Y CE V A + ML V +
Sbjct: 12415 KGKKYDIISKGAVRILVINKCLLDDEAEYSCE----VRTARTSGMLTVLEEEAVF--TKN 12468
Query: 343 TTTTTTTTTTTILTIITDSRAGEE 366
+ T TI + S+ G E
Sbjct: 12469 LANIEVSETDTIKLVCEVSKPGAE 12492
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVL----SGPNLFINNLNKTDNGTY 311
+ + G + +T G+P P V W + D ++ A + S +L I N N+ D+G Y
Sbjct: 26197 IVKAGASFTMTVPFRGRPVP-NVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKY 26255
Query: 312 RCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILT 356
N++ A ++ V D P PPT T T + +L+
Sbjct: 26256 TLTIQNVLSAASLTLVVKVLDTP---GPPTNITVQDVTKESAVLS 26297
Score = 41.6 bits (96), Expect = 0.001
Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 7/98 (7%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA------VLSGPNLFINNLNKTDNG 309
+ + G++L + G+P P VTW + E+ + VL +LF+ + + G
Sbjct: 27969 IIKSGESLRIKALVQGRPVP-RVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027
Query: 310 TYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTT 347
Y EA N G A ++ + V D P + P T T
Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNIT 28065
Score = 41.2 bits (95), Expect = 0.002
Identities = 60/297 (20%), Positives = 114/297 (38%), Gaps = 26/297 (8%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDV I G + C+V+ S + +F+D + +FS + +
Sbjct: 6748 KDVNAILGASVVLECRVSGSAPISVG---------WFQDGNEIVSGPKCQSSFSENVCTL 6798
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+L+ + SD G Y C + + + + P + + G + + +
Sbjct: 6799 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFT-SVI 6857
Query: 170 ASKPATTIRWFKGNTEL-KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVT 228
P ++WFKG+ EL G+S D VT + +V + G C V + A +
Sbjct: 6858 RGTPPFKVKWFKGSRELVPGESCNISLEDF--VTELELFEVQPLESG-DYSCLVTNDAGS 6914
Query: 229 GNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMP 288
+ T +++ +P ++ T G + L G P P+ V+W++ + +
Sbjct: 6915 ASCTTHLFVK---EPATFVKRLADFSVET--GSPIVLEATYTGTP-PISVSWIKDEYLIS 6968
Query: 289 QHA----VLSGPNLFINNLNKT--DNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPP 339
Q ++ + + L T D Y C N G+ + ++ V +PP I P
Sbjct: 6969 QSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEP 7025
Score = 39.3 bits (90), Expect = 0.007
Identities = 50/240 (20%), Positives = 94/240 (39%), Gaps = 27/240 (11%)
Query: 131 PQESYTTITVLVPPRNLMI-DIQKDT--------AVEGEEIEVNCTAMASKPATTIRWFK 181
P E I PPRN+ I DI K++ A +G ++ + + RW K
Sbjct: 26758 PSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGS-KITGYIVERRDLPDGRWTK 26816
Query: 182 GNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA-VTGNLQTQRYLEVQ 240
+ +E + T SQ +V + + + +P+ V G + ++
Sbjct: 26817 AS--FTNVTETQFIISGLTQNSQYEFRVFARN----AVGSISNPSEVVGPITC---IDSY 26867
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN--- 297
P + + + Y R G +++L GKP P + W + D E+ +A++ N
Sbjct: 26868 GGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPT-IEWYKDDKELQTNALVCVENTTD 26926
Query: 298 ---LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTI 354
+ I + ++ ++G Y + N +G A + + + D P P T T T +
Sbjct: 26927 LASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLL 26986
Score = 39.3 bits (90), Expect = 0.007
Identities = 47/209 (22%), Positives = 78/209 (37%), Gaps = 30/209 (14%)
Query: 171 SKPATTIRW----FKGNTELKG------KSEVEEWSDM---------YTVTSQLMLKVHK 211
SK ++ W F G E+ G K+++ +W + YTVT + +K
Sbjct: 28266 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 28325
Query: 212 -EDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAI 270
+ + + VTG ++ L P++ I + + R G ++ L
Sbjct: 28326 FRVSAINGAGKGDSCEVTGTIKAVDRLTA---PELDIDANFKQTHVVRAGASIRLFIAYQ 28382
Query: 271 GKPQPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDY 326
G+P P V W + D + H S L + N N+ D G Y N G +
Sbjct: 28383 GRPTPTAV-WSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITF 28441
Query: 327 MLYVYDPPTTIPPPTTTTTTTTTTTTTIL 355
+ V D P PP T T + T++
Sbjct: 28442 TVKVLDTPG--PPGPITFKDVTRGSATLM 28468
Score = 38.5 bits (88), Expect = 0.012
Identities = 35/163 (21%), Positives = 65/163 (39%), Gaps = 11/163 (6%)
Query: 174 ATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQT 233
A + FK +E++ S V E T T + + +E ++ T
Sbjct: 32493 AYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEK-ST 32551
Query: 234 QRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR---VDDEMPQH 290
R ++ ++ +T P EG++ +C+ G+P P VTW+R V +H
Sbjct: 32552 TRKIKTTLAARI---LTKPRSMTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLSTSARH 32607
Query: 291 AVLS---GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
V + I+++ +D G Y N GK +++ L +
Sbjct: 32608 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 32650
Score = 38.1 bits (87), Expect = 0.016
Identities = 49/249 (19%), Positives = 95/249 (38%), Gaps = 16/249 (6%)
Query: 100 LNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEG 159
++FS+ + + +V IS G+Y C + ++ ++ P ++ + G
Sbjct: 3972 MSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAG 4031
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ + T +A P +W+K L + +QL + D
Sbjct: 4032 DPATLEYT-VAGTPELKPKWYKDGRPLVASKKYR--ISFKNNVAQLKFYSAELHDSGQYT 4088
Query: 220 CQVEHPAVTGNLQTQ-RYLEVQYKPQVHIQMTYPLQGLTRE-GDALELTCEAIGKPQPVM 277
++ + + + +T L+ P T PL+ + L C+ G P+
Sbjct: 4089 FEISNEVGSSSCETTFTVLDRDIAPF----FTKPLRNVDSVVNGTCRLDCKIAGS-LPMR 4143
Query: 278 VTWVRVDDEMPQH-----AVLSGP-NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
V+W + E+ A + G +L I ++ D G + C A+N VG S L V
Sbjct: 4144 VSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203
Query: 332 DPPTTIPPP 340
+PP+ + P
Sbjct: 4204 EPPSFVTKP 4212
Score = 38.1 bits (87), Expect = 0.016
Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 7/116 (6%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS------GP 296
P++ + Y + G++ ++ + GKP P + W++ D E+ A L
Sbjct: 22541 PRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT-IQWIKGDQELSNTARLEIKSTDFAT 22599
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTT 352
+L + + + D+G Y +A N+ G+ + V D P P + T T
Sbjct: 22600 SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 22655
Score = 38.1 bits (87), Expect = 0.016
Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 257 TREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN------LFINNLNKTDNGT 310
T+ G+A +L+C+ +G+P P + W R E+ Q + L + + D G
Sbjct: 30544 TKLGEAAQLSCQIVGRPLP-DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 30602
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIP 338
Y C A+N VG+ + L + P P
Sbjct: 30603 YTCIATNEVGEVETSSKLLLQATPQFHP 30630
Score = 37.7 bits (86), Expect = 0.021
Identities = 70/292 (23%), Positives = 113/292 (38%), Gaps = 32/292 (10%)
Query: 57 GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSI 116
G +A +C++ + + Q R+ IY D ++ S++ S L++ T V
Sbjct: 3470 GHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIRSSKY------ISSLEILRTQVV- 3521
Query: 117 SDEGRYFCQLYTDPPQESYT---TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKP 173
D G Y C+ + S T T+T PP L T V G+ + CT +
Sbjct: 3522 -DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFV-GKAAKFICTVTGTPV 3579
Query: 174 ATTIRWFKGNTELKGKSEVEEW--SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL 231
TI W K L S W SD + + +D GV C+ +
Sbjct: 3580 IETI-WQKDGAAL---SPSPNWRISDAENKHILELSNLTIQDRGV-YSCKASNKFGADIC 3634
Query: 232 QTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA 291
Q + L + KP I+ P+Q + + L C+ + + + V VTW + ++P
Sbjct: 3635 QAE--LIIIDKPHF-IKELEPVQSAINK--KVHLECQ-VDEDRKVTVTWSKDGQKLPPGK 3688
Query: 292 VLSG------PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
L I D+GTY C ASN G + + V +PP+ +
Sbjct: 3689 DYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFV 3740
Score = 37.7 bits (86), Expect = 0.021
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 9/120 (7%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS------GP 296
P++ + + + + + G+A L + G+P P M W + E+ A L
Sbjct: 21459 PKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM-EWSKDGKELEGTAKLEIKIADFST 21517
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILT 356
NL + + D+G Y A+N G A + + V D P PP T T+ +L+
Sbjct: 21518 NLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPG--PPEGPLAVTEVTSEKCVLS 21575
Score = 37.7 bits (86), Expect = 0.021
Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN------LFINNLNKTDNGTYRC 313
G+ L + GKP P + W+R D E+ + A N L + + + D G Y
Sbjct: 23640 GETFRLEADVHGKPLPT-IEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 23698
Query: 314 EASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILT 356
ASN+ G + V D P PP T T+ LT
Sbjct: 23699 RASNVAGSKSFPVNVKVLDRPG--PPEGPVQVTGVTSEKCSLT 23739
Score = 37.4 bits (85), Expect = 0.027
Identities = 43/191 (22%), Positives = 71/191 (37%), Gaps = 24/191 (12%)
Query: 171 SKPATTIRWFK----GNTELKG--------KSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
+K + T+ W G ++ G + + W++ Y+V L L V +G
Sbjct: 18811 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTE-YSVVKDLSLVVTGLKEGKKY 18869
Query: 219 ICQVEHPAVTGNLQTQRYLEVQYKPQVHI---QMTYPLQGLTREGDALELTCEAIGKPQP 275
+V G + R E Y+ + + ++ P Q + G L + GKP P
Sbjct: 18870 KFRVAARNAVG-VSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHP 18928
Query: 276 VMVTWVRVDDE------MPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
W + +DE + H S L I ++ + D+G Y A N G +
Sbjct: 18929 TC-KWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 18987
Query: 330 VYDPPTTIPPP 340
V D P PP
Sbjct: 18988 VMDAPGPPQPP 18998
Score = 37.0 bits (84), Expect = 0.036
Identities = 51/257 (19%), Positives = 99/257 (38%), Gaps = 36/257 (14%)
Query: 106 ELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVE-GEEIEV 164
E + L V SD G Y C++ + + P + ++ ++ G+ ++
Sbjct: 4260 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQL 4319
Query: 165 NCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH 224
C + P I WF + E+K S+ S + + + V ED G +C+ ++
Sbjct: 4320 ACKVTGTPPIK-ITWFANDREIKESSK-HRMSFVESTAVLRLTDVGIEDSG-EYMCEAQN 4376
Query: 225 PAVTGN------LQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMV 278
A + + ++ Y ++KP + + Y + L E G P P +
Sbjct: 4377 EAGSDHCSSIVIVKESPYFTKEFKP-IEVLKEYDVM----------LLAEVAGTP-PFEI 4424
Query: 279 TWVRVDDEM----------PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYML 328
TW + + + H V +L I D G Y+C +N VG + +
Sbjct: 4425 TWFKDNTILRSGRKYKTFIQDHLV----SLQILKFVAADAGEYQCRVTNEVGSSICSARV 4480
Query: 329 YVYDPPTTIPPPTTTTT 345
+ +PP+ I +T++
Sbjct: 4481 TLREPPSFIKKIESTSS 4497
Score = 37.0 bits (84), Expect = 0.036
Identities = 57/271 (21%), Positives = 106/271 (39%), Gaps = 41/271 (15%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSR-FQLLNFSSSELKV 109
D+ V E E+A C++++ N + +F+D +K + + +++ + + V
Sbjct: 12382 DLQVREKEMARFECELSRE----------NAKVKWFKDGAEIKKGKKYDIISKGAVRILV 12431
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ + DE Y C++ T + +TVL ++ E + I++ C
Sbjct: 12432 -INKCLLDDEAEYSCEVRT---ARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV- 12486
Query: 170 ASKPATTIRWFKGNTEL--KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV 227
SKP + W+KG+ E+ G+ E+ + Q H ED G C++
Sbjct: 12487 -SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ---NAHLEDAG-NYNCRLPSSRT 12541
Query: 228 TGNLQTQRY-LEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
G ++ E KPQ ++++ EG+ E C + PV W R D
Sbjct: 12542 DGKVKVHELAAEFISKPQ-NLEIL--------EGEKAEFVCSISKESFPVQ--WKRDDKT 12590
Query: 287 MPQ----HAVLSGPN--LFINNLNKTDNGTY 311
+ + G L + + D GTY
Sbjct: 12591 LESGDKYDVIADGKKRVLVVKDATLQDMGTY 12621
Score = 36.6 bits (83), Expect = 0.047
Identities = 56/293 (19%), Positives = 110/293 (37%), Gaps = 37/293 (12%)
Query: 56 EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115
EG+ +C+++ P+ + +F++ P+ S ++ S + + + N S
Sbjct: 33147 EGQNVLFTCEISGE---------PSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNAS 33197
Query: 116 ISDEGRYFCQLYTDPPQESYTTITVLV-----PPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
+SD G+Y + Q S T +++ P R +++ DT+++G + A
Sbjct: 33198 VSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSA 33257
Query: 171 SKPATTIRWFKGN-----TELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHP 225
SK + F + TE+K S + M ++ + G+ + Q+E
Sbjct: 33258 SKQEASFSSFSSSSASSMTEMKFASMSAQ--SMSSMQESFVEMSSSSFMGISNMTQLES- 33314
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW----- 280
T + L+ + P EG L + C G+P P VTW
Sbjct: 33315 ------STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGR 33367
Query: 281 -VRVDDEMPQHAVLSG--PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ ++ H + L I ++ K D G Y N G + +++
Sbjct: 33368 KIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 36.2 bits (82), Expect = 0.061
Identities = 64/305 (20%), Positives = 113/305 (37%), Gaps = 35/305 (11%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
K+V VIE + A + +VN+ D +++D + FQ+ ++
Sbjct: 3154 KEVQVIEKQRAVVEFEVNEDDVDAH----------WYKDGIEIN---FQVQERHKYVVER 3200
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLV---PPRNLMIDIQKDTAVEGEEIEVNC 166
+ + IS+ + YT + +++T+ V P ++ ++Q T G+ C
Sbjct: 3201 RIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-C 3259
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
++ +P I W+K L + + D T L+++ ED V C+ ++
Sbjct: 3260 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL-LLIEAFPEDAAV-YTCEAKNDY 3317
Query: 227 VTGNLQTQRYLEV-------QYKPQVHIQMTYPLQG-LTREGDALELTCEAIGKPQPVMV 278
+EV Q P + PLQ +T EG C G + V
Sbjct: 3318 GVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTD--LKV 3375
Query: 279 TWVRVDDEMPQHAVLSGPN------LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
+W D ++ L I D GTY ASN VG+ S L +
Sbjct: 3376 SWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEA 3435
Query: 333 PPTTI 337
P + +
Sbjct: 3436 PESIL 3440
Score = 35.8 bits (81), Expect = 0.080
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 131 PQESYTTITV---LVPPRNLMIDIQKDTAV--EGEEIEVNCTAMASKPATTIRWFKGNTE 185
P ES IT + PPR M KDT V GE +V+ + KP TI+W KG+ E
Sbjct: 22525 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDAD-IYGKPIPTIQWIKGDQE 22583
Query: 186 LKGKSEVE 193
L + +E
Sbjct: 22584 LSNTARLE 22591
Score = 35.8 bits (81), Expect = 0.080
Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%)
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
P + +L Q L++ + TY +Q G+ L++ IG+P+P ++WV+
Sbjct: 24302 PVIAKDLTIQPSLKLPFN-------TYSIQA----GEDLKIEIPVIGRPRP-NISWVKDG 24349
Query: 285 DEMPQ------HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+ + Q + L I NK D G Y A+N G A + + V + P
Sbjct: 24350 EPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKP 24405
Score = 35.4 bits (80), Expect = 0.10
Identities = 25/108 (23%), Positives = 50/108 (46%), Gaps = 13/108 (12%)
Query: 25 RLRLLLLLFSAAALIPTGDGQNLFT---KDVTVIEGEVATISCQVNKSDDSVIQLLNPNR 81
++R+ + S+ A + +G FT +D T +E + + C+++K+D V
Sbjct: 11997 QIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVK------- 12049
Query: 82 QTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD 129
+F+D + +K S+ ++ + + L SD G+Y C TD
Sbjct: 12050 ---WFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTD 12094
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/85 (25%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS----GPNLFINNLNKTDNGTYRCEA 315
G + + GKP P VTW + +PQ A + ++ I N ++ G Y A
Sbjct: 16539 GGVIRIIAYVSGKPPPT-VTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLA 16597
Query: 316 SNIVGKAHSDYMLYVYDPPTTIPPP 340
N G+ ++ V D P + P
Sbjct: 16598 KNEAGERKKTIIVDVLDVPGPVGTP 16622
Score = 35.4 bits (80), Expect = 0.10
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 253 LQGLTREGDALELTCEAIGKPQPVMVTW---VRVDDEMPQHAVLSGPN---LFINNLNKT 306
+ + EG ++ C+ Q VTW VR + ++ + L++ ++ K
Sbjct: 31575 MHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 31634
Query: 307 DNGTYRCEASNIVGKAHSDYMLYV 330
D+GTYRC+ N G+ S L+V
Sbjct: 31635 DDGTYRCKVVNDYGEDSSYAELFV 31658
Score = 35.0 bits (79), Expect = 0.14
Identities = 33/118 (27%), Positives = 45/118 (38%), Gaps = 11/118 (9%)
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMP-----QHAVLSG-PNLFINNLNKTDNGTYR 312
EG+++ L C G P P VTW R D ++ Q SG L I D+G +
Sbjct: 956 EGESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFT 1014
Query: 313 CEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTIL----TIITDSRAGEE 366
C A N G + L V T T TT + ++TD+ EE
Sbjct: 1015 CSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1072
Score = 34.3 bits (77), Expect = 0.23
Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 15/138 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDVT E E A + ++L + N + +F++ + L +R + +
Sbjct: 11936 KDVTAKEKESAVFT----------VELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSI 11985
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ ++SI D + + S +TVL +Q T VE +E+ + C
Sbjct: 11986 TFKDLSIDDTSQIRVEAMG---MSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEI- 12041
Query: 170 ASKPATTIRWFKGNTELK 187
SK ++WFK E+K
Sbjct: 12042 -SKADAPVKWFKDGKEIK 12058
Score = 33.9 bits (76), Expect = 0.30
Identities = 26/103 (25%), Positives = 42/103 (40%), Gaps = 8/103 (7%)
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
E V G ++ LE P + Y R+G + LT GKP P+ W +
Sbjct: 30117 EPAEVPGTVKVTEMLEY---PDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI-CKWTK 30172
Query: 283 VDDEMPQHAVL----SGPNLFINNLNKTDNGTYRCEASNIVGK 321
++ + A++ + L I ++ D+GTY N GK
Sbjct: 30173 EGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGK 30215
Score = 33.5 bits (75), Expect = 0.40
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
K+VTVIEGE T+ C ++ + T Y D++ FQ + F S ++
Sbjct: 950 KNVTVIEGESVTLECHISGYPSPTV--------TWYREDYQIESSIDFQ-ITFQSGIARL 1000
Query: 110 SLTNVSISDEGRYFC 124
+ D GR+ C
Sbjct: 1001 MIREAFAEDSGRFTC 1015
Score = 33.5 bits (75), Expect = 0.40
Identities = 25/79 (31%), Positives = 30/79 (37%), Gaps = 5/79 (6%)
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS----GPNLFINNLNKTDNGTYRCEA 315
GD L L+ G P P VTW + D + P A + G L I N D G Y
Sbjct: 17233 GDTLRLSAIIKGVPFP-KVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTV 17291
Query: 316 SNIVGKAHSDYMLYVYDPP 334
N G + V D P
Sbjct: 17292 ENPAGSKTVSVKVLVLDKP 17310
Score = 33.1 bits (74), Expect = 0.52
Identities = 44/213 (20%), Positives = 76/213 (35%), Gaps = 12/213 (5%)
Query: 130 PPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK 189
PP + T + PP I + T IE+ A I + + +L G
Sbjct: 14989 PPSDPKTAHDPISPPGP---PIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGT 15045
Query: 190 SEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA---VTGNLQTQRYLEVQYKPQVH 246
+E ++ Q +K +E + + A G Q E Q P V
Sbjct: 15046 NEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVE 15105
Query: 247 IQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVL-----SGPNLFIN 301
+ ++ G L + G+P P V W + + E+ + V+ + L I
Sbjct: 15106 LDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV-WTKEEGELDKDRVVIDNVGTKSELIIK 15164
Query: 302 NLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+ + D+G Y A+N G + + V+D P
Sbjct: 15165 DALRKDHGRYVITATNSCGSKFAAARVEVFDVP 15197
Score = 33.1 bits (74), Expect = 0.52
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 83 TIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT-------DPPQESY 135
T Y + R L + R+ NFS+ L+ T ++++ Y ++ PP E
Sbjct: 21389 TSYIVEKRDLPNGRWLKANFSNI-LENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 21447
Query: 136 TTITVL--VPPRNLMIDIQ-KDTAV--EGEEIEVNCTAMASKPATTIRWFKGNTELKGKS 190
IT V + +D++ KDT + GE + ++ +P T+ W K EL+G +
Sbjct: 21448 DAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEAD-VSGRPPPTMEWSKDGKELEGTA 21506
Query: 191 EVE 193
++E
Sbjct: 21507 KLE 21509
Score = 33.1 bits (74), Expect = 0.52
Identities = 33/163 (20%), Positives = 59/163 (36%), Gaps = 10/163 (6%)
Query: 174 ATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQT 233
AT ++W EL E T + H+++ + I + + V
Sbjct: 33065 ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDL 33124
Query: 234 QRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW------VRVDDEM 287
E+ P ++ P EG + TCE G+P P + W + + +
Sbjct: 33125 TLSKELSDAPAF---ISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISSNV 33180
Query: 288 PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ +L I N + +D+G Y +A N G+ + L V
Sbjct: 33181 SISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 32.7 bits (73), Expect = 0.68
Identities = 43/189 (22%), Positives = 77/189 (40%), Gaps = 29/189 (15%)
Query: 171 SKPATTIRWFK----GNTELKG------KSEVEEWSDM-----YTVTSQLMLKVHKEDDG 215
+K + T+ W K G +E+ G K++ EEW + VT + K+ + +
Sbjct: 23932 TKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEY 23991
Query: 216 VPVICQV------EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEA 269
+C + E +V G ++ + LE P++ + + R G + +
Sbjct: 23992 KIRVCALNKVGLGEATSVPGTVKPEDKLEA---PELDLDSELRKGIVVRAGGSARIHIPF 24048
Query: 270 IGKPQPVMVTWVRVDDEMPQHAVLS-GPN---LFINNLNKTDNGTYRCEASNIVGKAHSD 325
G+P P +TW R + E + G N L I+N ++ D G Y + N G +
Sbjct: 24049 KGRPTPE-ITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF 24107
Query: 326 YMLYVYDPP 334
+ V D P
Sbjct: 24108 VTVKVLDTP 24116
Score = 32.0 bits (71), Expect = 1.2
Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 11/104 (10%)
Query: 253 LQGLT-REGDALELTCEAIGKPQPVMVTW-------VRVDDEMPQHAVLSGPNLFINNLN 304
LQ +T R+G + L G P PV+ + +D ++ Q L +L I
Sbjct: 110 LQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY--SLLIAEAY 167
Query: 305 KTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTT 348
D+GTY A+N VG+A S L V +P T T +T
Sbjct: 168 PEDSGTYSVNATNSVGRATSTAELLV-QGEEEVPAKKTKTIVST 210
Score = 32.0 bits (71), Expect = 1.2
Identities = 38/168 (22%), Positives = 71/168 (42%), Gaps = 21/168 (12%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDV VIEG A + C+V+ D + ++ Y D + D R Q + ++ ++
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKW--------YLNDEQIKPDDRVQAI-VKGTKQRL 2502
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ SDEG Y +L + T + V ++ ++ T E + +
Sbjct: 2503 VINRTHASDEGPY--KLIVGRVE---TNCNLSVEKIKIIRGLRDLTCTETQNVVFE--VE 2555
Query: 170 ASKPATTIRWFKGNTELK--GKSEVEEWSDMYTVTSQLMLKVHKEDDG 215
S + W + E+K K ++E +Y +T +L + K+D+G
Sbjct: 2556 LSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLT---VLNMMKDDEG 2600
Score = 32.0 bits (71), Expect = 1.2
Identities = 17/70 (24%), Positives = 40/70 (57%), Gaps = 8/70 (11%)
Query: 58 EVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS-RFQLLNFSSSELKVSLTNVSI 116
E+A ++C V + SV++ ++ +++D + LK++ FQ + ++ + N++
Sbjct: 32731 EIAKLTCVV---ESSVLRA----KEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 32783
Query: 117 SDEGRYFCQL 126
SD+G Y C++
Sbjct: 32784 SDQGEYVCEI 32793
Score = 31.6 bits (70), Expect = 1.5
Identities = 30/161 (18%), Positives = 75/161 (46%), Gaps = 15/161 (9%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELK- 108
++VTV++G+ +SC++NK R ++ +D + + + +++ ++
Sbjct: 11220 EEVTVVKGQPLYLSCELNK-----------ERDVVWRKDGKIVVEKPGRIVPGVIGLMRA 11268
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTA 168
+++ + +D G Y + E + + V+ R+ ++ +D V+ + +
Sbjct: 11269 LTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACD 11328
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKV 209
+A K I+WFKG E+ +E + +++ + L LK+
Sbjct: 11329 IA-KDTPNIKWFKGYDEI--PAEPNDKTEILRDGNHLYLKI 11366
Score = 31.6 bits (70), Expect = 1.5
Identities = 55/243 (22%), Positives = 85/243 (34%), Gaps = 30/243 (12%)
Query: 130 PPQESYTTITVL---VPPRNLMIDIQKD--TAVEGEEIEVNCTAMASKPATTIRWFKGNT 184
PP E +T+L VPPR + K T G + ++ T KP T+ W K T
Sbjct: 19276 PPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFG-KPMPTVSWKKDGT 19334
Query: 185 ELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKP- 243
LK ++ T +L V+++D G I +G+ L+V KP
Sbjct: 19335 LLKPAEGIKMAMQRNLCTLELF-SVNRKDSGDYTITAENS---SGSKSATIKLKVLDKPG 19390
Query: 244 ---QVHIQMTYPLQGLTR-----EGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSG 295
V I Y + + E E+T + K + W +V +P
Sbjct: 19391 PPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPI------ 19444
Query: 296 PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV-----YDPPTTIPPPTTTTTTTTTT 350
+ + L + +R A N G + YDPP PP + T
Sbjct: 19445 TSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHM 19504
Query: 351 TTT 353
T +
Sbjct: 19505 TVS 19507
Score = 31.6 bits (70), Expect = 1.5
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 30/204 (14%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDVT GE A +SCQ+ I+ ++ I R ++ D R L + E +
Sbjct: 30540 KDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE- 30598
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLV-------PPRNLMIDIQKDTAVEGEEI 162
DEG Y C + T+ E T+ +L+ P L +K G +
Sbjct: 30599 --------DEGVYTC-IATNEVGEVETSSKLLLQATPQFHPGYPLK---EKYYGAVGSTL 30646
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVE-EWSDMYT--VTSQLMLKVHKEDDGVPVI 219
++ +P + WF G L+ + E ++ YT V + K H
Sbjct: 30647 RLH-VMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK------ 30699
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKP 243
+V+ V G + +E+Q KP
Sbjct: 30700 YKVQLSNVFGTVDAILDVEIQDKP 30723
Score = 31.2 bits (69), Expect = 2.0
Identities = 28/123 (22%), Positives = 46/123 (37%), Gaps = 9/123 (7%)
Query: 238 EVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAV----- 292
++ + P+V + +T R G + + G+P+P +TW + + +
Sbjct: 17901 DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPD-ITWTKEGKVLVREKRVDLIQ 17959
Query: 293 -LSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTT 351
L L I + D+G Y A N G A ++ V D P P T T
Sbjct: 17960 DLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPG--PCQNLKVTNVTKEN 18017
Query: 352 TTI 354
TI
Sbjct: 18018 CTI 18020
Score = 31.2 bits (69), Expect = 2.0
Identities = 24/88 (27%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 271 GKPQPVMVTWVRVDDEMPQHAVLSGPN----LFINNLNKTDNGTYRCEASNIVGKAHSDY 326
G+P P V W R E A + + L + N+N+ D+G Y N G +
Sbjct: 21886 GRPAPE-VKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFV 21944
Query: 327 MLYVYDPPTTIPPPTTTTTTTTTTTTTI 354
+ V D P PP T T+ T+
Sbjct: 21945 NVRVLDTPG--PPQDLKVKEVTKTSVTL 21970
Score = 30.8 bits (68), Expect = 2.6
Identities = 70/326 (21%), Positives = 124/326 (38%), Gaps = 56/326 (17%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KD+ V+E + A C+V++ D +V + + I R +K + + ++ ++
Sbjct: 3065 KDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDR----IKIQKEKYVH------RL 3114
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMI-DIQKDTAVEGE-----EIE 163
+ + +SD G+ YT + +T + V R++ I I+K+ V + E E
Sbjct: 3115 LIPSTRMSDAGK-----YTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFE 3169
Query: 164 VNCTAMASKPATTIRWFKGNTELKGK-SEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
VN + W+K E+ + E ++ + + + + D G
Sbjct: 3170 VN------EDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAG------- 3216
Query: 223 EHPAVTGNLQTQ--RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAI-GKPQPVMVT 279
E+ V G ++ Y+ PQV LQ +T + C I G+PQP ++
Sbjct: 3217 EYTFVAGRNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQP-KIS 3271
Query: 280 WVRVDDEMPQ----HAVLSGP--NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDP 333
W + + + + G L + D Y CEA N G A + L V P
Sbjct: 3272 WYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP 3331
Query: 334 PTTIP-------PPTTTTTTTTTTTT 352
P PP T T T+
Sbjct: 3332 EVVSPDQEMPVYPPAIITPLQDTVTS 3357
Score = 30.8 bits (68), Expect = 2.6
Identities = 27/111 (24%), Positives = 43/111 (38%), Gaps = 16/111 (14%)
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDD--EMPQHAVL----------SGPNLFINNLNK 305
+ G+ + + + G P P + W + + E P A+ + L I +
Sbjct: 15411 KAGEPVHIPADVTGLPMP-KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 15469
Query: 306 TDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILT 356
D GTY ASN +G + + VYD P+ PP T + LT
Sbjct: 15470 EDKGTYTVTASNRLGSVFRNVHVEVYDRPS---PPRNLAVTDIKAESCYLT 15517
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/98 (22%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA---VLSGPN-- 297
P+V + + + + + G+ L++ + G+P PV ++W + E+ + A ++S N
Sbjct: 25787 PRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV-ISWAKDGIEIEERARTEIISTDNHT 25845
Query: 298 -LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
L + + + D G Y N+ G V D P
Sbjct: 25846 LLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKP 25883
Score = 30.0 bits (66), Expect = 4.4
Identities = 19/86 (22%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 83 TIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVL- 141
T + +D +++S + K+ + +V +SD G Y C L +++ T V+
Sbjct: 11149 TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 11208
Query: 142 -VPPRNLMIDIQKDTAVEGEEIEVNC 166
+P R + ++ T V+G+ + ++C
Sbjct: 11209 ELPVRFVKTLEEEVTVVKGQPLYLSC 11234
Score = 30.0 bits (66), Expect = 4.4
Identities = 26/112 (23%), Positives = 41/112 (36%), Gaps = 8/112 (7%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAV-------LSG 295
P + Y + G+ L + GKP P +V W + E+ + A +
Sbjct: 24705 PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVV-WSKDGKELEETAARMEIKSTIQK 24763
Query: 296 PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTT 347
L + + +TD G Y + SN+ G + V D P P T T
Sbjct: 24764 TTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVT 24815
Score = 29.6 bits (65), Expect = 5.7
Identities = 27/107 (25%), Positives = 42/107 (39%), Gaps = 10/107 (9%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTW----VRVDDEMPQHAVLSGPNLFIN--NLNKTDNG 309
+ R G + L G+P P +TW V + D + + + F+ N+NK D G
Sbjct: 19704 ILRAGVTMRLYVPVKGRPPP-KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 19762
Query: 310 TYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILT 356
Y N GK ++ V D P PP T + + +T
Sbjct: 19763 KYILTLENSCGKKEYTIVVKVLDTP---GPPVNVTVKEISKDSAYVT 19806
Score = 29.6 bits (65), Expect = 5.7
Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 11/83 (13%)
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEMPQHAV--------LSGPNLFINNLNKTDNGTY 311
G L++ G+P+P +TW + D +P L L I +K D G Y
Sbjct: 23244 GQDLKIEVPISGRPKPT-ITWTK--DGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300
Query: 312 RCEASNIVGKAHSDYMLYVYDPP 334
+N+VG+ + + D P
Sbjct: 23301 GITVANVVGQKTASIEIVTLDKP 23323
Score = 29.6 bits (65), Expect = 5.7
Identities = 53/277 (19%), Positives = 93/277 (33%), Gaps = 47/277 (16%)
Query: 84 IYFRDFRPLKDSRFQ---LLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITV 140
+Y +D L D ++ + ++ L + + Y+C+ + T+ +
Sbjct: 31626 LYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRL 31685
Query: 141 LVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELK-GKSEVEEWSDMY 199
L P + + TA GE + T + P + W+K ++K G ++ + +
Sbjct: 31686 LERPPEFTLPLYNKTAYVGENVRFGVT-ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESD 31744
Query: 200 TVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT-- 257
QL + DD E+ V N +Y E K ++ + + P T
Sbjct: 31745 KGLYQLTINSVTTDD------DAEYTVVARN----KYGEDSCKAKLTVTLHPPPTDSTLR 31794
Query: 258 ------------REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN-------- 297
+EG ++ G P P + W E + GPN
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTL-KW-----EKDGQPLSLGPNIEIIHEGL 31848
Query: 298 ----LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
L I + D G YR A+N G L V
Sbjct: 31849 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 29.3 bits (64), Expect = 7.5
Identities = 28/115 (24%), Positives = 42/115 (36%), Gaps = 9/115 (7%)
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS------GPNLFINNLNKTDNGTY 311
R G L L GKP+P ++ W + D E+ +S I +++D+G Y
Sbjct: 29060 RAGSDLVLDAAVGGKPEPKII-WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKY 29118
Query: 312 RCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRAGEE 366
N G M+ V D P P T + T T+ + G E
Sbjct: 29119 TLTVKNASGTKAVSVMVKVLDSPG--PCGKLTVSRVTQEKCTLAWSLPQEDGGAE 29171
Score = 28.9 bits (63), Expect = 9.8
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
LT +S + EG CQ +E + PR+ I+ EG+ + C ++
Sbjct: 33107 LTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNIN-------EGQNVLFTCE-IS 33158
Query: 171 SKPATTIRWFKGNTELKGKSEV 192
+P+ I WFK N + S V
Sbjct: 33159 GEPSPEIEWFKNNLPISISSNV 33180
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 75.5 bits (184), Expect = 9e-14
Identities = 67/255 (26%), Positives = 100/255 (39%), Gaps = 21/255 (8%)
Query: 105 SELKVSLTNVSISDEGRYFC----QLYTDPPQESYTTITVLVPPRNLMIDIQKD--TAVE 158
S + +++ SD G Y C L T Q T + P + ++ T
Sbjct: 3166 SHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEA 3225
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
G + C+A S PA TI W K + L W + ++ +V ++D G
Sbjct: 3226 GHTATLRCSATGS-PAPTIHWSKLRSPLP-------WQHRLEGDTLIIPRVAQQDSG-QY 3276
Query: 219 ICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMV 278
IC PA G+ + L V+ P T P + G+ ++L C A G P P+
Sbjct: 3277 ICNATSPA--GHAEATIILHVESPPYA---TTVPEHASVQAGETVQLQCLAHGTP-PLTF 3330
Query: 279 TWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP 338
W RV +P A L D+G YRC +N VG A + L V PP ++P
Sbjct: 3331 QWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLP 3390
Query: 339 PPTTTTTTTTTTTTT 353
+ +T T T
Sbjct: 3391 ATSIPAGSTPTVQVT 3405
Score = 74.3 bits (181), Expect = 2e-13
Identities = 67/238 (28%), Positives = 99/238 (41%), Gaps = 31/238 (13%)
Query: 118 DEGRYFCQLYTDPPQ-ESYTTITVLVPPRNL-------------MIDIQKDTAVEGEEIE 163
D GRY C++ E++ + V PP +L + Q +T G +E
Sbjct: 3359 DSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVE 3418
Query: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVP--VICQ 221
+C A+ S T +RWFK +L V++ +L++ D ICQ
Sbjct: 3419 FHC-AVPSDRGTQLRWFKEGGQLPPGHSVQDG----------VLRIQNLDQSCQGTYICQ 3467
Query: 222 VEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWV 281
P G Q L +Q P V I + +Q + G A+E C A+G P+P VTW
Sbjct: 3468 AHGP--WGKAQASAQLVIQALPSVLINIRTSVQTVV-VGHAVEFECLALGDPKP-QVTWS 3523
Query: 282 RVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPP 339
+V + V SG + I ++ D G YRC A+N G S +L V P P
Sbjct: 3524 KVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMP 3581
Score = 56.6 bits (135), Expect = 4e-08
Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 39/232 (16%)
Query: 108 KVSLTNVSISDEGRYFCQLYTDP-PQESYTTITVL-----------VP--PRNLMIDIQK 153
++ L VS +D G Y C++ P+E+ T++VL VP R + I+
Sbjct: 2101 RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSS 2160
Query: 154 DTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKED 213
EG+ +++NC A + W K L + + T +L++H+
Sbjct: 2161 SHVAEGQTLDLNCVVPGQAHAQ-VTWHKRGGSLPARHQ----------THGSLLRLHQVT 2209
Query: 214 --DGVPVICQVEHPAVTGNLQTQRYLEVQYK------PQVHIQMTYPLQGLTREGDALEL 265
D +C V +G L+ + ++ P V I+ + EG L+L
Sbjct: 2210 PADSGEYVCHVV--GTSGPLEASVLVTIEASVIPGPIPPVRIESS---SSTVAEGQTLDL 2264
Query: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASN 317
+C G+ VTW + +P + G L+I + D G Y C ASN
Sbjct: 2265 SCVVAGQAH-AQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASN 2315
Score = 55.8 bits (133), Expect = 7e-08
Identities = 56/243 (23%), Positives = 94/243 (38%), Gaps = 21/243 (8%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVP---PRNLMIDIQKDTAVEGEEIEVNCT 167
L V +D+ +Y C+ ++ Q+ + + PR + + ++ G + + C
Sbjct: 1920 LPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPR-VQVSPERTQVHAGRTVRLYCR 1978
Query: 168 AMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV 227
A A P+ TI W K L ++ E T + L++ D +C PA
Sbjct: 1979 A-AGVPSATITWRKEGGSLPPQARSER-----TDIATLLIPAITTADAGFYLCVATSPAG 2032
Query: 228 TGNLQTQRYL---EVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
T + Q + P V I+ + P EG L+L C G VTW R
Sbjct: 2033 TAQARIQVVVLSASDASPPPVKIESSSPS---VTEGQTLDLNCVVAGSAH-AQVTWYRRG 2088
Query: 285 DEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV----YDPPTTIPPP 340
+P H + G L + ++ D+G Y C N G + + V + P+ P P
Sbjct: 2089 GSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVP 2148
Query: 341 TTT 343
+T
Sbjct: 2149 GST 2151
Score = 55.8 bits (133), Expect = 7e-08
Identities = 70/307 (22%), Positives = 116/307 (37%), Gaps = 44/307 (14%)
Query: 53 TVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLT 112
TV+EG+ ++C V + ++I T Y R SR Q S L+ L
Sbjct: 2640 TVVEGQTLDLNCVVARQPQAII--------TWYKRGGS--LPSRHQT---HGSHLR--LH 2684
Query: 113 NVSISDEGRYFCQLYTD-PPQESYTTITVL-------VPPRNLMIDIQKDTA--VEGEEI 162
+S++D G Y C+ + E+ I+V P ++ I I+ ++ EGE +
Sbjct: 2685 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETL 2744
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
++NC A + W K L + T S+L L D +C+V
Sbjct: 2745 DLNCVVPGQAHAQ-VTWHKRGGSLPSHHQ--------TRGSRLRLHHVSPADSGEYVCRV 2795
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMT--------YPLQGLTREGDALELTCEAIGKPQ 274
+ +E VH+ P EG L+L C G+
Sbjct: 2796 MGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAH 2855
Query: 275 PVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY-DP 333
VTW + +P + GP L +N ++ D+G Y C+ + G + ++ +
Sbjct: 2856 -AQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSS 2914
Query: 334 PTTIPPP 340
P IP P
Sbjct: 2915 PGPIPAP 2921
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/237 (26%), Positives = 94/237 (39%), Gaps = 24/237 (10%)
Query: 111 LTNVSISDEGRYFCQLYTD--PPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTA 168
+ N+ S +G Y CQ + Q S + +P + I T V G +E C A
Sbjct: 3453 IQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLA 3512
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKV-HKE-DDGVPVICQVEHPA 226
+ P + W K L+ V S ++++ H E D C + A
Sbjct: 3513 LGD-PKPQVTWSKVGGHLRPG----------IVQSGGVVRIAHVELADAGQYRCTATNAA 3561
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
G Q+ L VQ PQ+ + P + G A C A G P P ++W ++D
Sbjct: 3562 --GTTQSHVLLLVQALPQISM----PQEVRVPAGSAAVFPCIASGYPTPD-ISWSKLDGS 3614
Query: 287 MPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTT 343
+P + L L + ++ D GTY C A+N GK + L V P +P T T
Sbjct: 3615 LPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV--PERVVPYFTQT 3669
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/256 (22%), Positives = 100/256 (39%), Gaps = 36/256 (14%)
Query: 114 VSISDEGRYFCQLYTDPPQESYTTITVLV------PPRNLMIDIQKDTAVEGEEIEVNCT 167
++ +D G Y C + T P + I V+V P + I+ + EG+ +++NC
Sbjct: 2015 ITTADAGFYLC-VATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCV 2073
Query: 168 AMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV 227
S A + W++ L ++V S+L L D +C+VE+
Sbjct: 2074 VAGSAHAQ-VTWYRRGGSLPPHTQVHG--------SRLRLPQVSPADSGEYVCRVEN--- 2121
Query: 228 TGNLQTQRYLEVQYKPQVHIQMTY-PLQGLTR------------EGDALELTCEAIGKPQ 274
G+ + + V H +Y P+ G TR EG L+L C G+
Sbjct: 2122 -GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAH 2180
Query: 275 PVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDP- 333
VTW + +P G L ++ + D+G Y C G + ++ +
Sbjct: 2181 -AQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASV 2239
Query: 334 -PTTIPPPTTTTTTTT 348
P IPP ++++T
Sbjct: 2240 IPGPIPPVRIESSSST 2255
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/246 (22%), Positives = 92/246 (37%), Gaps = 33/246 (13%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRN------------LMIDIQKDTAVE 158
L VS +D G Y CQ+ T ++ V + P + + I+ E
Sbjct: 2880 LNQVSPADSGEYSCQV-TGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTE 2938
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
G+ +++NC A + W+K L + + T SQL L + D
Sbjct: 2939 GQTLDLNCVVPGQAHAQ-VTWYKRGGSLPARHQ--------THGSQLRLHLVSPADSGEY 2989
Query: 219 ICQVEHPAVTGNLQTQRYLEV-------QYKPQVHIQMTYPLQGLTREGDALELTCEAIG 271
+C+ + G Q + Y+ + + P ++G C
Sbjct: 2990 VCRAA--SGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 3047
Query: 272 KPQPVMVTWVRVDDEMPQHAVLS--GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
P+ + W + E+ + +S G + I +++GTYRC ASN G A S L
Sbjct: 3048 GAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 3107
Query: 330 VYDPPT 335
V+ PPT
Sbjct: 3108 VHGPPT 3113
Score = 52.0 bits (123), Expect = 1e-06
Identities = 50/259 (19%), Positives = 97/259 (37%), Gaps = 24/259 (9%)
Query: 111 LTNVSISDEGRYFCQ-LYTDPPQESYTTITV--------LVPPRNLMIDIQKDTAVEGEE 161
L S +D G Y C+ L + P E+ +T+ L + I+ EG+
Sbjct: 2394 LYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQT 2453
Query: 162 IEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQ 221
+++NC +A + + W K L + +V S+L L D +C+
Sbjct: 2454 LDLNCL-VAGQAHAQVTWHKRGGSLPARHQVHG--------SRLRLLQVTPADSGEYVCR 2504
Query: 222 VEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQ-----GLTREGDALELTCEAIGKPQPV 276
V + T ++ + + YP++ G L+L C + P
Sbjct: 2505 VVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNC-LVASQAPH 2563
Query: 277 MVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTT 336
+TW + +P + G L I + D+G Y C SN G + ++ + ++
Sbjct: 2564 TITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSS 2623
Query: 337 IPPPTTTTTTTTTTTTTIL 355
P + +++ T++
Sbjct: 2624 HVPSVSPPIRIESSSPTVV 2642
Score = 50.1 bits (118), Expect = 4e-06
Identities = 48/239 (20%), Positives = 94/239 (39%), Gaps = 28/239 (11%)
Query: 108 KVSLTNVSISDEGRYFCQLYTDP-PQESYTTITV----------LVPPRNLMIDIQKDTA 156
++ + V+ +D G Y C + +E+ +T+ + PP + I+ T
Sbjct: 2584 RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP--IRIESSSPTV 2641
Query: 157 VEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGV 216
VEG+ +++NC +A +P I W+K L + + T S L L D
Sbjct: 2642 VEGQTLDLNC-VVARQPQAIITWYKRGGSLPSRHQ--------THGSHLRLHQMSVADSG 2692
Query: 217 PVICQVEH--PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT---REGDALELTCEAIG 271
+C+ + A+ ++ M ++ + EG+ L+L C G
Sbjct: 2693 EYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2752
Query: 272 KPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ VTW + +P H G L +++++ D+G Y C G + ++ +
Sbjct: 2753 QAH-AQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI 2810
Score = 48.1 bits (113), Expect = 2e-05
Identities = 60/252 (23%), Positives = 108/252 (42%), Gaps = 33/252 (13%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVE-GEEIEVNCTAM 169
+ V+ D G+Y C T P + TI + V + + +V+ GE +++ C A
Sbjct: 3265 IPRVAQQDSGQYICNA-TSPAGHAEATIILHVESPPYATTVPEHASVQAGETVQLQCLAH 3323
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLML--KVHKEDDGVPVICQVEHPAV 227
+ P T +W + + L G++ T ++L+ + ED G C+V +
Sbjct: 3324 GTPPLT-FQWSRVGSSLPGRA---------TARNELLHFERAAPEDSG-RYRCRVTNKV- 3371
Query: 228 TGNLQTQRYLEVQYKP------------QVHIQMTYPLQGLTREGDALELTCEAIGKPQP 275
G+ + L VQ P +Q+T L+ + G ++E C A+ +
Sbjct: 3372 -GSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSI-GASVEFHC-AVPSDRG 3428
Query: 276 VMVTWVRVDDEMPQ-HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+ W + ++P H+V G L I NL+++ GTY C+A GKA + L + P
Sbjct: 3429 TQLRWFKEGGQLPPGHSVQDGV-LRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALP 3487
Query: 335 TTIPPPTTTTTT 346
+ + T+ T
Sbjct: 3488 SVLINIRTSVQT 3499
Score = 47.4 bits (111), Expect = 3e-05
Identities = 54/260 (20%), Positives = 99/260 (38%), Gaps = 35/260 (13%)
Query: 111 LTNVSISDEGRYFCQLY-TDPPQESYTTITVL-------VPPRNLMIDIQKDTAVEGEEI 162
L V+ +D G Y C + T P E+ +T+ +PP + I+ T EG+ +
Sbjct: 2205 LHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPP--VRIESSSSTVAEGQTL 2262
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
+++C +A + + W+K L + +V S+L + D +C+
Sbjct: 2263 DLSCV-VAGQAHAQVTWYKRGGSLPARHQVRG--------SRLYIFQASPADAGQYVCRA 2313
Query: 223 EHP-------AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQP 275
+ VTG + I+ P EG L+L C G+
Sbjct: 2314 SNGMEASITVTVTGTQGANLAYPAGSTQPIRIE---PSSSQVAEGQTLDLNCVVPGQSH- 2369
Query: 276 VMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCE--ASNIVGKAHSDYMLYVYDP 333
VTW + +P G L + + D+G Y C S++ +A +L +P
Sbjct: 2370 AQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEAS---VLVTIEP 2426
Query: 334 PTTIPPPTTTTTTTTTTTTT 353
++P T T ++++
Sbjct: 2427 AGSVPALGVTPTVRIESSSS 2446
Score = 46.6 bits (109), Expect = 5e-05
Identities = 56/260 (21%), Positives = 93/260 (35%), Gaps = 38/260 (14%)
Query: 109 VSLTNVSISDEGRYFCQ-------------LYTDPPQESYTTITVLVPPRNLMIDIQKDT 155
+++ NV +SD G Y C L+ + + PP+ T
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQL--------T 1876
Query: 156 AVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQLMLKVHKEDD 214
G+ E C+A S P T+ W G +L K+++ L L + D
Sbjct: 1877 VQPGQLAEFRCSATGS-PTPTLEWTGGPGGQLPAKAQIHG--------GILRLPAVEPTD 1927
Query: 215 GVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQ 274
+C+ A G + L V +Q++ P + G + L C A G P
Sbjct: 1928 QAQYLCRAHSSA--GQQVARAVLHVHGGGGPRVQVS-PERTQVHAGRTVRLYCRAAGVPS 1984
Query: 275 PVMVTWVRVDDEMPQHAVLSGPN---LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
+TW + +P A + L I + D G Y C A++ G A + + V
Sbjct: 1985 AT-ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVL 2043
Query: 332 DPPTTIPPPTTTTTTTTTTT 351
PPP +++ + T
Sbjct: 2044 SASDASPPPVKIESSSPSVT 2063
Score = 45.8 bits (107), Expect = 8e-05
Identities = 50/239 (20%), Positives = 94/239 (39%), Gaps = 17/239 (7%)
Query: 113 NVSISDEGRYFCQLYTDPPQESYTTITVLVP-----PRNLMIDIQKDTAVE-GEEIEVNC 166
+V SD G Y C + Q + + +LV P + ++ Q+ +V G ++ C
Sbjct: 1735 SVQPSDAGVYICTC-RNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFIC 1793
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
TA + PA T+ W + + K + +++ + T+ + V D G +C +
Sbjct: 1794 TAKSKSPAYTLVWTRLHNG-KLPTRAMDFNGILTIRN-----VQLSDAGT-YVCTGSNMF 1846
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
+++ + +P Q + G E C A G P P + +
Sbjct: 1847 AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQ 1906
Query: 287 MPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY---DPPTTIPPPTT 342
+P A + G L + + TD Y C A + G+ + +L+V+ P + P T
Sbjct: 1907 LPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERT 1965
Score = 37.4 bits (85), Expect = 0.027
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 11/85 (12%)
Query: 243 PQVHIQMTYPLQGL-TREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN---- 297
PQV +T P + + G + TC AIG P P+ + W +P H ++ +
Sbjct: 406 PQV---VTPPRESIQASRGQTVTFTCVAIGVPTPI-INWRLNWGHIPSHPRVTVTSEGGR 461
Query: 298 --LFINNLNKTDNGTYRCEASNIVG 320
L I ++ ++D G Y CEA N G
Sbjct: 462 GTLIIRDVKESDQGAYTCEAMNARG 486
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 75.5 bits (184), Expect = 9e-14
Identities = 66/286 (23%), Positives = 117/286 (40%), Gaps = 22/286 (7%)
Query: 79 PNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTI 138
P+ ++ +D P+ + L ++L + SD GRY C + ++ +
Sbjct: 2005 PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 2064
Query: 139 TVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDM 198
+ P +++ + + V E + + C + A P + W+K L+ + V +D
Sbjct: 2065 LQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSWWKDGRPLEPRPGVHLSAD- 2122
Query: 199 YTVTSQLMLKVHKED--DGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL 256
+ +L+V + D D C+ + A G+ + L V P ++ ++ L
Sbjct: 2123 -----KALLQVDRADVWDAGHYTCEALNQA--GHSEKHYNLNVWVAPVFPLRESHTLT-- 2173
Query: 257 TREGDALELTCEAIGKPQPVMVTWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGT 310
REG L+CE G P P ++W + +P QH G L++ GT
Sbjct: 2174 VREGHPTSLSCECRGVPFP-KISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 2232
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPP--PTTTTTTTTTTTTTI 354
Y CE SN+VG + D L V+ PP P P T + T+
Sbjct: 2233 YTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATL 2278
Score = 74.3 bits (181), Expect = 2e-13
Identities = 86/313 (27%), Positives = 122/313 (38%), Gaps = 32/313 (10%)
Query: 42 GDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS-RFQLL 100
GD + L ++VTV ++ C L NP + ++ P S R Q+L
Sbjct: 2846 GDTEEL-VEEVTVNASSTVSLQCPA---------LGNPVPTISWLQNGLPFSPSPRLQVL 2895
Query: 101 NFSSSELKVSLTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNLMIDIQKDTAVEG 159
L+VS V+ D Y C E T+ V VPPR +D+++ TA+
Sbjct: 2896 E-DGQVLQVSTAEVA--DAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILN 2952
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ + C A P + W+K + L EV + T L L + D
Sbjct: 2953 SSVSLPCDVHAH-PNPEVTWYKDSQALSLGEEVF----LLPGTHTLQLGRARLSDSGMYT 3007
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQG-LTREGDALELTCEAIGKPQPVMV 278
C+ + A G Q L V P P L R GD L+CE P+P V
Sbjct: 3008 CEALNAA--GRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPT-V 3064
Query: 279 TWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
TW + D P A+ G L I +D G Y C+ SN+ G+A + L V
Sbjct: 3065 TWYK--DGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV 3122
Query: 333 PPTTIPPPTTTTT 345
PPT P T T +
Sbjct: 3123 PPTFENPKTETVS 3135
Score = 73.2 bits (178), Expect = 5e-13
Identities = 74/305 (24%), Positives = 121/305 (39%), Gaps = 21/305 (6%)
Query: 33 FSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL 92
F A L+ + ++ V+EG+ + C+ + P + +D PL
Sbjct: 3208 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQ---------PPPDVAWLKDGSPL 3258
Query: 93 KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDI 151
L F + L + SD G Y C + +++ T+ VLVPP
Sbjct: 3259 GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 3318
Query: 152 QKDTAVE--GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKV 209
T V GE + + C S P + W K L +T+ + KV
Sbjct: 3319 GSGTLVSRPGELVTMVCPVRGSPPIH-VSWLKDGLPLPLSQRTLLHGSGHTLR---ISKV 3374
Query: 210 HKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEA 269
D G+ C PA G L+VQ P + + + + G +EL CEA
Sbjct: 3375 QLADAGI-FTCVAASPA--GVADRNFTLQVQVPPVLE-PVEFQNDVVVVRGSLVELPCEA 3430
Query: 270 IGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
G P P +V+W++ + + ++ GP+L + + D+GTY C A + G+A + L
Sbjct: 3431 RGVPLP-LVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT 3489
Query: 330 VYDPP 334
V +PP
Sbjct: 3490 VMEPP 3494
Score = 68.9 bits (167), Expect = 9e-12
Identities = 78/314 (24%), Positives = 115/314 (36%), Gaps = 28/314 (8%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVS 110
+V+V+ E + CQ + V+ +++D RPL+ ++ S+ + +
Sbjct: 2079 NVSVVANESVALECQSHAMPPPVLS---------WWKDGRPLEPRPG--VHLSADKALLQ 2127
Query: 111 LTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ + D G Y C+ E + + V V P + + T EG ++C
Sbjct: 2128 VDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR 2187
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
P I W K L G E + V L L + C+ + V G
Sbjct: 2188 GV-PFPKISWRKDGQPLPG--EGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN--VVG 2242
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ 289
N LEV PQ+ P Q + L C A GKP P VTW R D P
Sbjct: 2243 NSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT-VTWER--DGQPV 2299
Query: 290 HAVLS------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP--PPT 341
A L G +L + G Y C A N+ G+A + L V PP I P
Sbjct: 2300 GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPL 2359
Query: 342 TTTTTTTTTTTTIL 355
T T + T+L
Sbjct: 2360 TNITAALHSPLTLL 2373
Score = 61.6 bits (148), Expect = 1e-09
Identities = 58/231 (25%), Positives = 90/231 (38%), Gaps = 22/231 (9%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
L V + D G Y C S+ + + P + + + GE +++NC A
Sbjct: 1086 LAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEG 1145
Query: 171 SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGN 230
+ P + W K L+G+ + + D C+ + A
Sbjct: 1146 N-PEPQLSWSKDGVVLQGRGP----------QGSVHFAAIRTSDAGRYRCEASNSAGVDA 1194
Query: 231 LQTQRYLEVQYKPQVHIQMTYPLQGLTR-EGDALELTCEAIGKPQPVMVTWVRVDDEMPQ 289
+ + L V P T L L R G+ L C A G P+P VTW + P
Sbjct: 1195 WEVE--LRVLEPPHWGADETSGL--LERVAGENASLPCPARGTPKP-QVTWRKGPSSEPL 1249
Query: 290 H-----AVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
H AVL +LF+ +++ D+G Y C+A+N VG L VY PP+
Sbjct: 1250 HGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPS 1300
Score = 61.2 bits (147), Expect = 2e-09
Identities = 59/239 (24%), Positives = 101/239 (42%), Gaps = 24/239 (10%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTIT--VLVPPRNLMIDIQKDTAVEGEEIEVNC 166
+ + V + DEG Y C T+ ES + VLVPP N+ +E + + C
Sbjct: 1850 LQIEKVDLRDEGIYTCAA-TNLAGESKREVALKVLVPP-NIEPGPVNKAVLENASVTLEC 1907
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKED--DGVPVICQVEH 224
A + P + WFKG+ V W + +L++ + D C +
Sbjct: 1908 LA-SGVPPPDVSWFKGH------QPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 1960
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
V G+ + + L V P++ + + P G + LTC A G P P ++ W++
Sbjct: 1961 --VAGSTELRYGLRVNVPPRITLPPSLP--GPVLVNTPVRLTCNATGAPSPTLM-WLKDG 2015
Query: 285 DEM-----PQHAVLSGPN-LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
+ + P V G L + + +D+G Y C A + VG+ D +L V+ PP+ +
Sbjct: 2016 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL 2074
Score = 60.5 bits (145), Expect = 3e-09
Identities = 70/317 (22%), Positives = 127/317 (40%), Gaps = 36/317 (11%)
Query: 33 FSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL 92
FS L+P + + V++G+ A + C V +P + +F+D RPL
Sbjct: 2436 FSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTG---------HPQPKLTWFKDGRPL 2486
Query: 93 KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQES-YTTITVLVPPRNLMIDI 151
+R + S + + + ++S G Y C +++ + ++VL+ P ++
Sbjct: 2487 --ARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPT--ILGG 2542
Query: 152 QKDTAVEGEEIEVN------CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQL 205
+D+A E + VN C A+A P+ I W K + ++ + +
Sbjct: 2543 AEDSADEEVTVTVNNPISLICEALAF-PSPNITWMKDGAPFEASRNIQLLPGTHGLQ--- 2598
Query: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL----TREGD 261
+L KED G C V + G ++EV P + G+ T+
Sbjct: 2599 ILNAQKEDAG-QYTCVVTNEL--GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNS 2655
Query: 262 ALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS----GPNLFINNLNKTDNGTYRCEASN 317
L L CE+ P P + W + + + L G L I +D+G Y C A+N
Sbjct: 2656 TLTLECESWAVPPPT-IRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 2714
Query: 318 IVGKAHSDYMLYVYDPP 334
+ G+ D+ + + PP
Sbjct: 2715 VAGEDDQDFNVLIQVPP 2731
Score = 60.5 bits (145), Expect = 3e-09
Identities = 68/300 (22%), Positives = 120/300 (40%), Gaps = 23/300 (7%)
Query: 45 QNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSS 104
+N T+ V+ + G ++C V+ P + +D P++ S S
Sbjct: 3127 ENPKTETVSQVAGSPLVLTCDVSGV---------PAPTVTWLKDRMPVESSAVH--GVVS 3175
Query: 105 SELKVSLTNVSISDEGRYFCQLY-TDPPQESYTTITVLVPPRNLMIDIQKDTAV-EGEEI 162
++ L+ + + G Y C T + VLV PR + ++ V EG+E+
Sbjct: 3176 RGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV 3235
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
++C A +P + W K + L ++ Y L+LK + D C
Sbjct: 3236 RLDCEA-DGQPPPDVAWLKDGSPLG--QDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVA 3292
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
+PA G + V P + ++R G+ + + C G P P+ V+W++
Sbjct: 3293 HNPA--GEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSP-PIHVSWLK 3349
Query: 283 VDDEMP--QHAVL--SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP 338
+P Q +L SG L I+ + D G + C A++ G A ++ L V PP P
Sbjct: 3350 DGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEP 3409
Score = 60.1 bits (144), Expect = 4e-09
Identities = 77/300 (25%), Positives = 121/300 (40%), Gaps = 45/300 (15%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLK-DSRFQLLNFSSSELKVS 110
V V G+ A +SC+ + P +++D +PL R Q L ++
Sbjct: 3042 VLVRVGDKAVLSCETDAL---------PEPTVTWYKDGQPLVLAQRTQALRGGQ---RLE 3089
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ +SD+G Y C++ + T T+TV VPP + + V G + + C +
Sbjct: 3090 IQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD-V 3148
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ---LMLKVHKEDDGVPVICQVEHPA 226
+ PA T+ W LK + VE S ++ V S+ L L + C E+
Sbjct: 3149 SGVPAPTVTW------LKDRMPVES-SAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN-- 3199
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE-----LTCEAIGKPQPVMVTWV 281
TQ + V + G+ RE LE L CEA G+P P V W+
Sbjct: 3200 ------TQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD-VAWL 3252
Query: 282 R----VDDEMPQHA--VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
+ + +M H L G +L + L +D G Y C A N G+ + + V PPT
Sbjct: 3253 KDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 3312
Score = 57.8 bits (138), Expect = 2e-08
Identities = 76/312 (24%), Positives = 120/312 (38%), Gaps = 37/312 (11%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL-KDSRFQLLNFSSSELKVS 110
V+V++ VAT+ C P + RD +P+ + QL N S +
Sbjct: 2268 VSVVQDGVATLECNATGK---------PPPTVTWERDGQPVGAELGLQLQNQGQS---LH 2315
Query: 111 LTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNL--MIDIQKDTAVEGEEIEVNCT 167
+ + GRY C + E ++VLVPP + + + TA + + C
Sbjct: 2316 VERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCE 2375
Query: 168 AMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHK--EDDGVPVICQVEHP 225
AM P IRWF+G + V D Y + MLK+ + E D C +
Sbjct: 2376 AMGIPPPA-IRWFRG------EEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNE 2428
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTR--EGDALELTCEAIGKPQPVMVTWVRV 283
A G + +EV P + + L+ + + +G L C G PQP + TW +
Sbjct: 2429 A--GEARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKL-TWFKD 2482
Query: 284 DDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPP 339
+ + H G L + N + G Y C A+N VG+ + L V PT +
Sbjct: 2483 GRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGG 2542
Query: 340 PTTTTTTTTTTT 351
+ T T
Sbjct: 2543 AEDSADEEVTVT 2554
Score = 57.4 bits (137), Expect = 3e-08
Identities = 74/298 (24%), Positives = 120/298 (40%), Gaps = 30/298 (10%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVS 110
+VTV GE A +SC+V L + RD+R L S ++ + L++S
Sbjct: 525 NVTVSPGETAVLSCRV---------LGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEIS 575
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPR-NLMIDIQKDTAVEGEEIEVNCTAM 169
+ +D GRY C + ++ + ++ +LV + I +G E++V+C+A
Sbjct: 576 --GIIPTDGGRYQC-VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSA- 631
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
+ P I W + + L+ S + L+++ +D CQ + T
Sbjct: 632 SGYPTPHISWSRESQALQEDSRIH-----VDAQGTLIIQGVAPEDAGNYSCQATNEVGTD 686
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEM-- 287
Q + + Y + + L G+ L CEA G P P V W R EM
Sbjct: 687 ----QETVTLYYTDPPSVSAVNAVV-LVAVGEEAVLVCEASGVPPP-RVIWYRGGLEMIL 740
Query: 288 -PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTT 344
P+ + S L I + D GTY C A N +G A ++ L V P P T
Sbjct: 741 APEGS--SSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVT 796
Score = 56.6 bits (135), Expect = 4e-08
Identities = 86/335 (25%), Positives = 130/335 (38%), Gaps = 41/335 (12%)
Query: 9 GSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNK 68
G + A +P G + R L A PT G N T +V V+E + + C+
Sbjct: 1473 GDEGRYQCVAFSPAGQQARDFQLRVHAP---PTIWGSNE-TGEVAVMEDHLVQLLCEARG 1528
Query: 69 SDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT 128
P +F+D L S + +L+ L SD G Y C+
Sbjct: 1529 V---------PTPNITWFKDGALLPTSTKVVYTRGGRQLQ--LGRAQSSDAGVYTCKASN 1577
Query: 129 DP-PQESYTTITVLVPP-------RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
E T + V VPP R ++ AV G + + C A P+ T+ W
Sbjct: 1578 AVGAAEKATRLDVYVPPTIEGAGGRPYVVK-----AVAGRPVALECVARGH-PSPTLSWH 1631
Query: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
+ +E S + T S L L+ E C PA G Q +EVQ
Sbjct: 1632 HEGLPVAESNE----SRLETDGSVLRLESPGEASSGLYSCVASSPA--GEAVLQYSVEVQ 1685
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWV---RVDDEMPQHAVLS-GP 296
PQ+ + Q T G LEL C+A G P P + W+ R +E+ V S G
Sbjct: 1686 VPPQLLVAEGLG-QVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQVASQGT 1743
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
L I+++ +G + C+A+N G A ++ + V+
Sbjct: 1744 TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 1778
Score = 55.8 bits (133), Expect = 7e-08
Identities = 69/280 (24%), Positives = 115/280 (41%), Gaps = 32/280 (11%)
Query: 62 ISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV-SLTNVSISDEG 120
+SC V+ + +QL + R F+ +S +++L S +E T VS + G
Sbjct: 446 VSCSVHSALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTG 505
Query: 121 RYFCQLY-TDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRW 179
R Q+ TDPP + LVP N+ T GE ++C + P + W
Sbjct: 506 RAKAQIVVTDPPPQ-------LVPAPNV-------TVSPGETAVLSCRVLGEAPYN-LTW 550
Query: 180 FKGNTELKGKS-EVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLE 238
+ L + V + +D+ S ++ DG C + G + +L
Sbjct: 551 VRDWRVLPASTGRVAQLADLSLEISGII-----PTDGGRYQCVASN--ANGVTRASVWLL 603
Query: 239 VQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA---VLSG 295
V+ PQV I + +G ++++C A G P P ++W R + + + V +
Sbjct: 604 VREAPQVSIHTS---SQHFSQGVEVKVSCSASGYPTP-HISWSRESQALQEDSRIHVDAQ 659
Query: 296 PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
L I + D G Y C+A+N VG LY DPP+
Sbjct: 660 GTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPS 699
Score = 53.9 bits (128), Expect = 3e-07
Identities = 54/225 (24%), Positives = 88/225 (39%), Gaps = 19/225 (8%)
Query: 113 NVSISDEGRYFCQ---LYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+V+ D+ Y C+ ++ E+ +T PP+ + +EG+ + + C +
Sbjct: 851 SVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQ-IASSAPTVRVLEGQPVSLPCIVL 909
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
A +P W K L S +D L L ++ C + A G
Sbjct: 910 AGRPLPERHWLKDGRPLPPGSRHSIRAD-----GSLHLDRALQEHAGRYSCVATNTA--G 962
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEM-- 287
+ L VQ P++H T+ + T EG L C A G P P +TW + + +
Sbjct: 963 SQHRDVELVVQVPPRIHPTATHHI---TNEGVPASLPCVASGVPAPT-ITWTKETNALTS 1018
Query: 288 --PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
P + V L I + D G Y C A+N VG + + L V
Sbjct: 1019 RGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV 1063
Score = 52.8 bits (125), Expect = 6e-07
Identities = 58/249 (23%), Positives = 99/249 (39%), Gaps = 21/249 (8%)
Query: 104 SSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVE-GEEI 162
SS K+ + D G Y C+ + S I + V + ++ +D VE G
Sbjct: 745 SSSGKLRIPAAQERDAGTYTCRAVNELGDAS-AEIQLAVGHAPQLTELPRDVTVELGRSA 803
Query: 163 EVNCTAMASKPATTIRWFKGNTEL------KGKSEVEEWSDMYTVTSQLMLKVHKEDDGV 216
+ C A +P T+ W +G+ + G+ D + L + +D
Sbjct: 804 LLACRA-TGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPD----SGVLFFESVAPEDQA 858
Query: 217 PVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAI-GKPQP 275
P +C+ + V G +Q + L V I + P + EG + L C + G+P P
Sbjct: 859 PYVCEARN--VFGKVQAEARLIVTGHAPPQIASSAPTVRVL-EGQPVSLPCIVLAGRPLP 915
Query: 276 VMVTWVRVDDEMP---QHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
W++ +P +H++ + +L ++ + G Y C A+N G H D L V
Sbjct: 916 ER-HWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQV 974
Query: 333 PPTTIPPPT 341
PP P T
Sbjct: 975 PPRIHPTAT 983
Score = 52.0 bits (123), Expect = 1e-06
Identities = 60/233 (25%), Positives = 92/233 (39%), Gaps = 21/233 (9%)
Query: 108 KVSLTNVSISDEGRYFCQLYTDPPQE-SYTTITVLVPP--RNLMIDIQKDTAVEGEEIEV 164
++ + + S D G Y C T + V VPP N + D+ + EG +
Sbjct: 4001 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDL---STTEGSHAFL 4057
Query: 165 NCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH 224
C A S P I W K + G E + +L++K + D C E+
Sbjct: 4058 PCKARGS-PEPNITWDKDGQPVSGA----EGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 4112
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
G + + +L + P + T P R GD L L C A G P P + W V+
Sbjct: 4113 --AVGRARRRVHLTILVLP---VFTTLPGDRSLRLGDRLWLRCAARGSPTP-RIGWT-VN 4165
Query: 285 DEMPQHAVLS---GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
D V G L +++ D+GTY C A N VG+ + ++V + P
Sbjct: 4166 DRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 4218
Score = 51.2 bits (121), Expect = 2e-06
Identities = 77/349 (22%), Positives = 135/349 (38%), Gaps = 47/349 (13%)
Query: 38 LIPT--GDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS 95
L PT G ++ ++VTV ++ C+ L P+ + +D P + S
Sbjct: 2535 LAPTILGGAEDSADEEVTVTVNNPISLICEA---------LAFPSPNITWMKDGAPFEAS 2585
Query: 96 R-FQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT--ITVLVPPRNLMIDIQ 152
R QLL + + + N D G+Y C + T+ E+ + VL+PP D
Sbjct: 2586 RNIQLLPGTHG---LQILNAQKEDAGQYTC-VVTNELGEAVKNYHVEVLIPPSISKDDPL 2641
Query: 153 KDTAVEGEEIEVNCTAMA-----SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLML 207
+ V+ + +VN T + P TIRW+K + S ++ + L +
Sbjct: 2642 GEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE----GRLLQI 2697
Query: 208 KVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDA----- 262
+ + D +C + A + ++V Q + + L+RE +A
Sbjct: 2698 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVT 2757
Query: 263 ----------LELTCEAIGKPQPVMVTWVRVDDEMP---QHAVLSGPNLFINNLNKTDN- 308
L C+ P P + TW R D + + +VL G + L + +N
Sbjct: 2758 EYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENA 2816
Query: 309 GTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTI 357
G Y C+ASN VG+ Y L V PP + T ++ +++
Sbjct: 2817 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 2865
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 26/193 (13%)
Query: 156 AVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDG 215
AV EE+ + C A + P TI W K +G + S QL + +D
Sbjct: 3959 AVAEEEVLLPCEA-SGIPRPTITWQK-----EGLNVATGVSTQVLPGGQLRIAHASPEDA 4012
Query: 216 VPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL----TREGDALELTCEAIG 271
+C ++ A G+ + L VQ P + GL T EG L C+A G
Sbjct: 4013 GNYLCIAKNSA--GSAMGKTRLVVQVPPVIE-------NGLPDLSTTEGSHAFLPCKARG 4063
Query: 272 KPQPVMVTWVR----VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYM 327
P+P +TW + V + + L + NL D GTY C A N VG+A
Sbjct: 4064 SPEP-NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVH 4122
Query: 328 LYVYDPP--TTIP 338
L + P TT+P
Sbjct: 4123 LTILVLPVFTTLP 4135
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/179 (24%), Positives = 71/179 (39%), Gaps = 15/179 (8%)
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
G I+++C P I W K L+G + + L + + DD
Sbjct: 4233 GGSIQLDCVVRGD-PVPDIHWIKDGLPLRGSHLRHQLQN-----GSLTIHRTERDDAGRY 4286
Query: 219 ICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMV 278
C E+ G + L +Q P ++ P R GD + L C+A G+P P +
Sbjct: 4287 QCLAENEM--GVAKKVVILVLQSAPVFQVE---PQDMTVRSGDDVALRCQATGEPTPT-I 4340
Query: 279 TWVRVDDEMPQHA---VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
W++ + L +L++ N+ D GTY C A N++G A + L V P
Sbjct: 4341 EWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEP 4399
Score = 49.7 bits (117), Expect = 5e-06
Identities = 57/231 (24%), Positives = 90/231 (38%), Gaps = 16/231 (6%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAV-EGEEIEVNCTA 168
+T + DEGRY C ++ Q++ + V PP + + AV E +++ C A
Sbjct: 1467 ITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEA 1526
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTS-QLMLKVHKEDDGVPVICQVEHPAV 227
P I WFK L ++V +YT QL L + D C+ +
Sbjct: 1527 RGV-PTPNITWFKDGALLPTSTKV-----VYTRGGRQLQLGRAQSSDAGVYTCKASN--A 1578
Query: 228 TGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW----VRV 283
G + L+V P + P G + L C A G P P + +W + V
Sbjct: 1579 VGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL-SWHHEGLPV 1637
Query: 284 DDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+ G L + + + +G Y C AS+ G+A Y + V PP
Sbjct: 1638 AESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 1688
Score = 49.3 bits (116), Expect = 7e-06
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTWV---RVDDEMPQHA--VLSGPNLFINNLNKTDNGT 310
LT AL L CEA G P+P++V W ++D + Q A +L L + D+
Sbjct: 3775 LTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ 3833
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTT 346
+ C SN VG+AH Y + V+ PPT T T T
Sbjct: 3834 FECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVT 3869
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/228 (25%), Positives = 86/228 (37%), Gaps = 22/228 (9%)
Query: 118 DEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDT-AVEGEEIEVNCTAMASKPA 174
D G Y C+ Q + + VL PP L ++ + G ++E+ C + P
Sbjct: 1380 DSGLYSCRAENQAGTAQRDFHLL-VLTPPSVLGAGAAQEVLGLAGADVELQCWT-SGVPT 1437
Query: 175 TTIRWFKGNTELKGKS---EVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL 231
+ W K + +V+E + +T H D+G C PA G
Sbjct: 1438 PQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGS-----HVGDEG-RYQCVAFSPA--GQQ 1489
Query: 232 QTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA 291
L V P + + E ++L CEA G P P +TW + +P
Sbjct: 1490 ARDFQLRVHAPPTIW-GSNETGEVAVMEDHLVQLLCEARGVPTP-NITWFKDGALLPTST 1547
Query: 292 VL----SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
+ G L + +D G Y C+ASN VG A L VY PPT
Sbjct: 1548 KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPT 1595
Score = 47.4 bits (111), Expect = 3e-05
Identities = 69/306 (22%), Positives = 118/306 (38%), Gaps = 54/306 (17%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
+TV EG ++SC+ P + + +D +PL L + S+ + L
Sbjct: 2172 LTVREGHPTSLSCECRGV---------PFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 2222
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTT-ITVLVPPR-------NLMIDIQKDTAVEGEEIE 163
++ EG Y C+ S + V VPP+ + + +D +E
Sbjct: 2223 GQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVAT---LE 2279
Query: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI-CQV 222
N T KP T+ W + D V ++L L++ + + V Q
Sbjct: 2280 CNATG---KPPPTVTWER---------------DGQPVGAELGLQLQNQGQSLHVERAQA 2321
Query: 223 EHPA--------VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTRE-GDALELTCEAIGKP 273
H + G + + L V P++ I PL +T L L CEA+G P
Sbjct: 2322 AHTGRYSCVAENLAGRAERKFELSVLVPPEL-IGDLDPLTNITAALHSPLTLLCEAMGIP 2380
Query: 274 QPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
P + W R ++ + + + G L + + D+G Y C ASN G+A ++ +
Sbjct: 2381 PPA-IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVE 2439
Query: 330 VYDPPT 335
V PP+
Sbjct: 2440 VLVPPS 2445
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/344 (21%), Positives = 121/344 (35%), Gaps = 51/344 (14%)
Query: 18 AAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLL 77
AA+P G+ R L ++ + QN DV V+ G + + C+ ++
Sbjct: 3386 AASPAGVADRNFTLQVQVPPVLEPVEFQN----DVVVVRGSLVELPCEARGVPLPLVS-- 3439
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQ-ESYT 136
+ +D PL + + L V D G Y C ++ + +
Sbjct: 3440 -------WMKDGEPLLSQSLE------QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF 3486
Query: 137 TITVLVPPRNLMIDIQKDTAVE---GEEIEVNCTAMASKPATTIRWFKGN---TELKGKS 190
+TV+ PP + D + T + G +E+ C A + P I W K T L+ S
Sbjct: 3487 QLTVMEPPH--IEDSGQPTELSLTPGAPMELLCDAQGT-PQPNITWHKDGQALTRLENNS 3543
Query: 191 EVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMT 250
+V + D C E PA G ++ + VQ P + +
Sbjct: 3544 RAT--------------RVLRVRDAGLYTCLAESPA--GAIEKSFRVRVQAPPNI-VGPR 3586
Query: 251 YPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN----LFINNLNKT 306
P + L L C +P P +TW R + + A P L + L+
Sbjct: 3587 GPRFVVGLAPGQLVLECSVEAEPAP-KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA 3645
Query: 307 DNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTT 350
D+G Y C A N G + + ++ PT P + T
Sbjct: 3646 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT 3689
Score = 47.4 bits (111), Expect = 3e-05
Identities = 31/89 (34%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 265 LTCEAIGKPQPVMVTW----VRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVG 320
L C+A G P P +V+W V +D P+ +L +L I + D G Y C ASN G
Sbjct: 3692 LPCQADGVPAP-LVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG 3750
Query: 321 KAHSDYMLYVYDPPTTIPPPTTTTTTTTT 349
L V +PP P P+ T T T
Sbjct: 3751 SDRQGRDLRVLEPPAIAPSPSNLTLTAHT 3779
Score = 45.8 bits (107), Expect = 8e-05
Identities = 64/299 (21%), Positives = 114/299 (38%), Gaps = 41/299 (13%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT- 136
+P+ + + P+ +S L S L+ L + + G Y C + + P E+
Sbjct: 1623 HPSPTLSWHHEGLPVAESNESRLETDGSVLR--LESPGEASSGLYSC-VASSPAGEAVLQ 1679
Query: 137 -TITVLVPPRNLMID-IQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEE 194
++ V VPP+ L+ + + + T + G+ +E+ C A S P TI+W L+ EE
Sbjct: 1680 YSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGS-PVPTIQW------LQNGRPAEE 1732
Query: 195 WSDMYTVTSQLMLKV-HKEDDGVPVI-CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYP 252
+ + + L + H E D + CQ + A T + + + ++ P V
Sbjct: 1733 LAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQ 1792
Query: 253 LQGLTREGDALELTCEAI------GKPQPVMV-------------TWVRVDDEMPQHAVL 293
+ C+ P+P +V T + V +P
Sbjct: 1793 YHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLP----- 1847
Query: 294 SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTT 352
P L I ++ D G Y C A+N+ G++ + L V PP P P + T
Sbjct: 1848 --PPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVT 1904
Score = 45.4 bits (106), Expect = 1e-04
Identities = 59/252 (23%), Positives = 93/252 (36%), Gaps = 33/252 (13%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTA--VEGEEIEVNC 166
V + SD GRY C+ +++ ++ P + D V GE + C
Sbjct: 1169 VHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPC 1228
Query: 167 TAMASKPATTIRWFKGNTE--LKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH 224
A + P + W KG + L G+ V + S + V D G CQ +
Sbjct: 1229 PARGT-PKPQVTWRKGPSSEPLHGQPGVAVLEE----GSLFLASVSPADSG-DYECQATN 1282
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQ-MTYPLQGLTREGDALELTCEAIGKPQPVMVT---- 279
G+ + L V P + + G+ G +L L C+A G P P +V
Sbjct: 1283 EV--GSTSRRAKLVVYVPPSIREDGRKANVSGMA--GQSLTLECDANGFPVPEIVWLKDA 1338
Query: 280 -------------WVRVDDEMPQHAVLS-GPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325
W ++ H +L G +L + + D+G Y C A N G A D
Sbjct: 1339 QLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRD 1398
Query: 326 YMLYVYDPPTTI 337
+ L V PP+ +
Sbjct: 1399 FHLLVLTPPSVL 1410
Score = 45.1 bits (105), Expect = 1e-04
Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 11/138 (7%)
Query: 208 KVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTC 267
KV D+G+ + G + + L+V P + P+ E ++ L C
Sbjct: 1854 KVDLRDEGIYTCAATN---LAGESKREVALKVLVPPNIE---PGPVNKAVLENASVTLEC 1907
Query: 268 EAIGKPQPVMVTWVR----VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAH 323
A G P P V+W + V M + G L I +D G+YRC ASN+ G
Sbjct: 1908 LASGVPPPD-VSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTE 1966
Query: 324 SDYMLYVYDPPTTIPPPT 341
Y L V PP PP+
Sbjct: 1967 LRYGLRVNVPPRITLPPS 1984
Score = 41.2 bits (95), Expect = 0.002
Identities = 59/250 (23%), Positives = 96/250 (38%), Gaps = 46/250 (18%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAV-EGEEIEVNC 166
+ +T D G Y C + + ++ VLVPP D+++ V +G+ + C
Sbjct: 2408 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMC 2467
Query: 167 TAMASKPATTIRWFKGNTEL-KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHP 225
+ P + WFK L +G + H DGV + +
Sbjct: 2468 N-VTGHPQPKLTWFKDGRPLARGDAH------------------HISPDGVLLQVLQANL 2508
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREG--------------DALELTCEAIG 271
+ G+ V K + H Q++ L G + + L CEA+
Sbjct: 2509 SSAGHYSCIAANAVGEKTK-HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 2567
Query: 272 KPQPVMVTWVRVDDEMPQHA-----VLSGPN-LFINNLNKTDNGTYRCEASNIVGKAHSD 325
P P +TW++ D P A +L G + L I N K D G Y C +N +G+A +
Sbjct: 2568 FPSP-NITWMK--DGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 2624
Query: 326 YMLYVYDPPT 335
Y + V PP+
Sbjct: 2625 YHVEVLIPPS 2634
Score = 37.4 bits (85), Expect = 0.027
Identities = 62/292 (21%), Positives = 96/292 (32%), Gaps = 62/292 (21%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
V V+EG+ ++ C ++ P + + +D RPL + S + L
Sbjct: 894 VRVLEGQPVSLPC--------IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGS---LHL 942
Query: 112 TNVSISDEGRYFC-QLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
GRY C T Q + V VPPR + EG + C A +
Sbjct: 943 DRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPR-IHPTATHHITNEGVPASLPCVA-S 1000
Query: 171 SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ--LMLKVHKEDDGVPVICQVEHPAVT 228
PA TI W K L + Y V+ + L++ D +C +
Sbjct: 1001 GVPAPTITWTKETNALTSRGP------HYNVSKEGTLLIAQPSAQDAGAYVCTATNTV-- 1052
Query: 229 GNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMP 288
G + + L + A+ K W
Sbjct: 1053 --------------------------GFSSQEMRLSVNRLALSK-----YVW-------E 1074
Query: 289 QHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPP 340
++ +L +L + + D+G Y C ASN G A Y+L V PP P P
Sbjct: 1075 EYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGP 1126
Score = 36.6 bits (83), Expect = 0.047
Identities = 37/162 (22%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 85 YFRDFRPLKDS--RFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLV 142
+ +D PL+ S R QL N S +++ D GRY C + I VL
Sbjct: 4252 WIKDGLPLRGSHLRHQLQNGS-----LTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ 4306
Query: 143 PPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
++ Q T G+++ + C A +P TI W + L+ + D
Sbjct: 4307 SAPVFQVEPQDMTVRSGDDVALRCQA-TGEPTPTIEWLQAGQPLRASRRLRTLPD----- 4360
Query: 203 SQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
L L+ + D C + + G+ + +L V+ +PQ
Sbjct: 4361 GSLWLENVETGDAGTYDCVAHN--LLGSATARAFLVVRGEPQ 4400
Score = 33.1 bits (74), Expect = 0.52
Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 5/81 (6%)
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVG 320
LTC + G P P V+W + ++ + V L I G Y C A N G
Sbjct: 3876 LTCHSTGIPAPT-VSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 3934
Query: 321 KAHSDYMLYVYDPPTTIPPPT 341
AH L V P P P+
Sbjct: 3935 VAHKHVFLTVQASPVVKPLPS 3955
Score = 32.0 bits (71), Expect = 1.2
Identities = 14/58 (24%), Positives = 25/58 (43%)
Query: 304 NKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDS 361
+K + GTY C A + G + + V DPP + P T + T ++ ++
Sbjct: 487 SKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVPAPNVTVSPGETAVLSCRVLGEA 544
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 75.5 bits (184), Expect = 9e-14
Identities = 66/286 (23%), Positives = 117/286 (40%), Gaps = 22/286 (7%)
Query: 79 PNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTI 138
P+ ++ +D P+ + L ++L + SD GRY C + ++ +
Sbjct: 723 PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 782
Query: 139 TVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDM 198
+ P +++ + + V E + + C + A P + W+K L+ + V +D
Sbjct: 783 LQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSWWKDGRPLEPRPGVHLSAD- 840
Query: 199 YTVTSQLMLKVHKED--DGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL 256
+ +L+V + D D C+ + A G+ + L V P ++ ++ L
Sbjct: 841 -----KALLQVDRADVWDAGHYTCEALNQA--GHSEKHYNLNVWVAPVFPLRESHTLT-- 891
Query: 257 TREGDALELTCEAIGKPQPVMVTWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGT 310
REG L+CE G P P ++W + +P QH G L++ GT
Sbjct: 892 VREGHPTRLSCECRGVPFP-KISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 950
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPP--PTTTTTTTTTTTTTI 354
Y CE SN+VG + D L V+ PP P P T + T+
Sbjct: 951 YTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATL 996
Score = 74.3 bits (181), Expect = 2e-13
Identities = 86/313 (27%), Positives = 122/313 (38%), Gaps = 32/313 (10%)
Query: 42 GDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS-RFQLL 100
GD + L ++VTV ++ C L NP + ++ P S R Q+L
Sbjct: 1564 GDTEEL-VEEVTVNASSTVSLQCPA---------LGNPVPTISWLQNGLPFSPSPRLQVL 1613
Query: 101 NFSSSELKVSLTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNLMIDIQKDTAVEG 159
L+VS V+ D Y C E T+ V VPPR +D+++ TA+
Sbjct: 1614 E-DGQVLQVSTAEVA--DAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILN 1670
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ + C A P + W+K + L EV + T L L + D
Sbjct: 1671 SSVSLPCDVHAH-PNPEVTWYKDSQALSLGEEVF----LLPGTHTLQLGRARLSDSGMYT 1725
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQG-LTREGDALELTCEAIGKPQPVMV 278
C+ + A G Q L V P P L R GD L+CE P+P V
Sbjct: 1726 CEALNAA--GRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPT-V 1782
Query: 279 TWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
TW + D P A+ G L I +D G Y C+ SN+ G+A + L V
Sbjct: 1783 TWYK--DGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV 1840
Query: 333 PPTTIPPPTTTTT 345
PPT P T T +
Sbjct: 1841 PPTFENPKTETVS 1853
Score = 73.2 bits (178), Expect = 5e-13
Identities = 74/305 (24%), Positives = 121/305 (39%), Gaps = 21/305 (6%)
Query: 33 FSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL 92
F A L+ + ++ V+EG+ + C+ + P + +D PL
Sbjct: 1926 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQ---------PPPDVAWLKDGSPL 1976
Query: 93 KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDI 151
L F + L + SD G Y C + +++ T+ VLVPP
Sbjct: 1977 GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 2036
Query: 152 QKDTAVE--GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKV 209
T V GE + + C S P + W K L +T+ + KV
Sbjct: 2037 GSGTLVSRPGELVTMVCPVRGSPPIH-VSWLKDGLPLPLSQRTLLHGSGHTLR---ISKV 2092
Query: 210 HKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEA 269
D G+ C PA G L+VQ P + + + + G +EL CEA
Sbjct: 2093 QLADAGI-FTCVAASPA--GVADRNFTLQVQVPPVLE-PVEFQNDVVVVRGSLVELPCEA 2148
Query: 270 IGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
G P P +V+W++ + + ++ GP+L + + D+GTY C A + G+A + L
Sbjct: 2149 RGVPLP-LVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT 2207
Query: 330 VYDPP 334
V +PP
Sbjct: 2208 VMEPP 2212
Score = 68.9 bits (167), Expect = 9e-12
Identities = 78/314 (24%), Positives = 115/314 (36%), Gaps = 28/314 (8%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVS 110
+V+V+ E + CQ + V+ +++D RPL+ ++ S+ + +
Sbjct: 797 NVSVVANESVALECQSHAMPPPVLS---------WWKDGRPLEPRPG--VHLSADKALLQ 845
Query: 111 LTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ + D G Y C+ E + + V V P + + T EG ++C
Sbjct: 846 VDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECR 905
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
P I W K L G E + V L L + C+ + V G
Sbjct: 906 GV-PFPKISWRKDGQPLPG--EGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN--VVG 960
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ 289
N LEV PQ+ P Q + L C A GKP P VTW R D P
Sbjct: 961 NSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT-VTWER--DGQPV 1017
Query: 290 HAVLS------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP--PPT 341
A L G +L + G Y C A N+ G+A + L V PP I P
Sbjct: 1018 GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPL 1077
Query: 342 TTTTTTTTTTTTIL 355
T T + T+L
Sbjct: 1078 TNITAALHSPLTLL 1091
Score = 61.2 bits (147), Expect = 2e-09
Identities = 59/239 (24%), Positives = 101/239 (42%), Gaps = 24/239 (10%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTIT--VLVPPRNLMIDIQKDTAVEGEEIEVNC 166
+ + V + DEG Y C T+ ES + VLVPP N+ +E + + C
Sbjct: 568 LQIEKVDLRDEGIYTCAA-TNLAGESKREVALKVLVPP-NIEPGPVNKAVLENASVTLEC 625
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKED--DGVPVICQVEH 224
A + P + WFKG+ V W + +L++ + D C +
Sbjct: 626 LA-SGVPPPDVSWFKGH------QPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 678
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
V G+ + + L V P++ + + P G + LTC A G P P ++ W++
Sbjct: 679 --VAGSTELRYGLRVNVPPRITLPPSLP--GPVLVNTPVRLTCNATGAPSPTLM-WLKDG 733
Query: 285 DEM-----PQHAVLSGPN-LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
+ + P V G L + + +D+G Y C A + VG+ D +L V+ PP+ +
Sbjct: 734 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL 792
Score = 60.8 bits (146), Expect = 2e-09
Identities = 70/317 (22%), Positives = 127/317 (40%), Gaps = 36/317 (11%)
Query: 33 FSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL 92
FS L+P + + V++G+ A + C V +P + +F+D RPL
Sbjct: 1154 FSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTG---------HPQPKLTWFKDGRPL 1204
Query: 93 KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQES-YTTITVLVPPRNLMIDI 151
+R + S + + + ++S G Y C +++ + ++VL+ P ++
Sbjct: 1205 --ARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPT--ILGG 1260
Query: 152 QKDTAVEGEEIEVN------CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQL 205
+D+A E + VN C A+A P+ I W K + ++ + +
Sbjct: 1261 AEDSADEEVTVTVNNPISLICEALAF-PSPNITWMKDGAPFEASRNIQLLPGTHGLQ--- 1316
Query: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL----TREGD 261
+L KED G C V + G ++EV P + G+ T+
Sbjct: 1317 ILNAQKEDAG-QYTCVVTNEL--GEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNS 1373
Query: 262 ALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS----GPNLFINNLNKTDNGTYRCEASN 317
L L CE+ P P + W + + + L G L I +D+G Y C A+N
Sbjct: 1374 TLTLECESWAVPPPT-IRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 1432
Query: 318 IVGKAHSDYMLYVYDPP 334
+ G+ D+ + + PP
Sbjct: 1433 VAGEDDQDFNVLIQVPP 1449
Score = 60.5 bits (145), Expect = 3e-09
Identities = 68/300 (22%), Positives = 120/300 (40%), Gaps = 23/300 (7%)
Query: 45 QNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSS 104
+N T+ V+ + G ++C V+ P + +D P++ S S
Sbjct: 1845 ENPKTETVSQVAGSPLVLTCDVSGV---------PAPTVTWLKDRMPVESSAVH--GVVS 1893
Query: 105 SELKVSLTNVSISDEGRYFCQLY-TDPPQESYTTITVLVPPRNLMIDIQKDTAV-EGEEI 162
++ L+ + + G Y C T + VLV PR + ++ V EG+E+
Sbjct: 1894 RGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV 1953
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
++C A +P + W K + L ++ Y L+LK + D C
Sbjct: 1954 RLDCEA-DGQPPPDVAWLKDGSPLG--QDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVA 2010
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
+PA G + V P + ++R G+ + + C G P P+ V+W++
Sbjct: 2011 HNPA--GEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSP-PIHVSWLK 2067
Query: 283 VDDEMP--QHAVL--SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP 338
+P Q +L SG L I+ + D G + C A++ G A ++ L V PP P
Sbjct: 2068 DGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEP 2127
Score = 60.1 bits (144), Expect = 4e-09
Identities = 77/300 (25%), Positives = 121/300 (40%), Gaps = 45/300 (15%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLK-DSRFQLLNFSSSELKVS 110
V V G+ A +SC+ + P +++D +PL R Q L ++
Sbjct: 1760 VLVRVGDKAVLSCETDAL---------PEPTVTWYKDGQPLVLAQRTQALRGGQ---RLE 1807
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ +SD+G Y C++ + T T+TV VPP + + V G + + C +
Sbjct: 1808 IQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD-V 1866
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ---LMLKVHKEDDGVPVICQVEHPA 226
+ PA T+ W LK + VE S ++ V S+ L L + C E+
Sbjct: 1867 SGVPAPTVTW------LKDRMPVES-SAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN-- 1917
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE-----LTCEAIGKPQPVMVTWV 281
TQ + V + G+ RE LE L CEA G+P P V W+
Sbjct: 1918 ------TQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD-VAWL 1970
Query: 282 R----VDDEMPQHA--VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
+ + +M H L G +L + L +D G Y C A N G+ + + V PPT
Sbjct: 1971 KDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 2030
Score = 57.8 bits (138), Expect = 2e-08
Identities = 76/312 (24%), Positives = 120/312 (38%), Gaps = 37/312 (11%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL-KDSRFQLLNFSSSELKVS 110
V+V++ VAT+ C P + RD +P+ + QL N S +
Sbjct: 986 VSVVQDGVATLECNATGK---------PPPTVTWERDGQPVGAELGLQLQNQGQS---LH 1033
Query: 111 LTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNL--MIDIQKDTAVEGEEIEVNCT 167
+ + GRY C + E ++VLVPP + + + TA + + C
Sbjct: 1034 VERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCE 1093
Query: 168 AMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHK--EDDGVPVICQVEHP 225
AM P IRWF+G + V D Y + MLK+ + E D C +
Sbjct: 1094 AMGIPPPA-IRWFRG------EEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNE 1146
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTR--EGDALELTCEAIGKPQPVMVTWVRV 283
A G + +EV P + + L+ + + +G L C G PQP + TW +
Sbjct: 1147 A--GEARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKL-TWFKD 1200
Query: 284 DDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPP 339
+ + H G L + N + G Y C A+N VG+ + L V PT +
Sbjct: 1201 GRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGG 1260
Query: 340 PTTTTTTTTTTT 351
+ T T
Sbjct: 1261 AEDSADEEVTVT 1272
Score = 56.6 bits (135), Expect = 4e-08
Identities = 86/335 (25%), Positives = 130/335 (38%), Gaps = 41/335 (12%)
Query: 9 GSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNK 68
G + A +P G + R L A PT G N T +V V+E + + C+
Sbjct: 191 GDEGRYQCVAFSPAGQQARDFQLRVHAP---PTIWGSNE-TGEVAVMEDHLVQLLCEARG 246
Query: 69 SDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT 128
P +F+D L S + +L+ L SD G Y C+
Sbjct: 247 V---------PTPNITWFKDGALLPTSTKVVYTRGGRQLQ--LGRAQSSDAGVYTCKASN 295
Query: 129 DP-PQESYTTITVLVPP-------RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
E T + V VPP R ++ AV G + + C A P+ T+ W
Sbjct: 296 AVGAAEKATRLDVYVPPTIEGAGGRPYVVK-----AVAGRPVALECVARGH-PSPTLSWH 349
Query: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
+ +E S + T S L L+ E C PA G Q +EVQ
Sbjct: 350 HEGLPVAESNE----SRLETDGSVLRLESPGEASSGLYSCVASSPA--GEAVLQYSVEVQ 403
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWV---RVDDEMPQHAVLS-GP 296
PQ+ + Q T G LEL C+A G P P + W+ R +E+ V S G
Sbjct: 404 VPPQLLVAEGLG-QVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQVASQGT 461
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
L I+++ +G + C+A+N G A ++ + V+
Sbjct: 462 TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 496
Score = 52.0 bits (123), Expect = 1e-06
Identities = 60/233 (25%), Positives = 92/233 (39%), Gaps = 21/233 (9%)
Query: 108 KVSLTNVSISDEGRYFCQLYTDPPQE-SYTTITVLVPP--RNLMIDIQKDTAVEGEEIEV 164
++ + + S D G Y C T + V VPP N + D+ + EG +
Sbjct: 2719 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDL---STTEGSHAFL 2775
Query: 165 NCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH 224
C A S P I W K + G E + +L++K + D C E+
Sbjct: 2776 PCKARGS-PEPNITWDKDGQPVSGA----EGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 2830
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
G + + +L + P + T P R GD L L C A G P P + W V+
Sbjct: 2831 --AVGRARRRVHLTILVLP---VFTTLPGDRSLRLGDRLWLRCAARGSPTP-RIGWT-VN 2883
Query: 285 DEMPQHAVLS---GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
D V G L +++ D+GTY C A N VG+ + ++V + P
Sbjct: 2884 DRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 2936
Score = 52.0 bits (123), Expect = 1e-06
Identities = 44/179 (24%), Positives = 72/179 (40%), Gaps = 15/179 (8%)
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
G I+++C P I W K L+G + + L ++ + DD
Sbjct: 2951 GGSIQLDCVVRGD-PVPDIHWIKDGLPLRGSHLRHQLQN-----GSLTIRRTERDDAGRY 3004
Query: 219 ICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMV 278
C E+ G + L +Q P ++ P R GD + L C+A G+P P +
Sbjct: 3005 QCLAENEM--GVAKKVVILVLQSAPVFQVE---PQDMTVRSGDDVALRCQATGEPTPT-I 3058
Query: 279 TWVRVDDEMPQHA---VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
W++ + L +L++ N+ D GTY C A N++G A + L V P
Sbjct: 3059 EWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEP 3117
Score = 51.6 bits (122), Expect = 1e-06
Identities = 77/349 (22%), Positives = 135/349 (38%), Gaps = 47/349 (13%)
Query: 38 LIPT--GDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS 95
L PT G ++ ++VTV ++ C+ L P+ + +D P + S
Sbjct: 1253 LAPTILGGAEDSADEEVTVTVNNPISLICEA---------LAFPSPNITWMKDGAPFEAS 1303
Query: 96 R-FQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT--ITVLVPPRNLMIDIQ 152
R QLL + + + N D G+Y C + T+ E+ + VL+PP D
Sbjct: 1304 RNIQLLPGTHG---LQILNAQKEDAGQYTC-VVTNELGEAVKNYHVEVLIPPSISKDDPL 1359
Query: 153 KDTAVEGEEIEVNCTAMA-----SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLML 207
+ V+ + +VN T + P TIRW+K + S ++ + L +
Sbjct: 1360 AEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE----GRLLQI 1415
Query: 208 KVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDA----- 262
+ + D +C + A + ++V Q + + L+RE +A
Sbjct: 1416 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVT 1475
Query: 263 ----------LELTCEAIGKPQPVMVTWVRVDDEMP---QHAVLSGPNLFINNLNKTDN- 308
L C+ P P + TW R D + + +VL G + L + +N
Sbjct: 1476 EYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENA 1534
Query: 309 GTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTI 357
G Y C+ASN VG+ Y L V PP + T ++ +++
Sbjct: 1535 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1583
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 26/193 (13%)
Query: 156 AVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDG 215
AV EE+ + C A + P TI W K +G + S QL + +D
Sbjct: 2677 AVAEEEVLLPCEA-SGIPRPTITWQK-----EGLNVATGVSTQVLPGGQLRIAHASPEDA 2730
Query: 216 VPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL----TREGDALELTCEAIG 271
+C ++ A G+ + L VQ P + GL T EG L C+A G
Sbjct: 2731 GNYLCIAKNSA--GSAMGKTRLVVQVPPVIE-------NGLPDLSTTEGSHAFLPCKARG 2781
Query: 272 KPQPVMVTWVR----VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYM 327
P+P +TW + V + + L + NL D GTY C A N VG+A
Sbjct: 2782 SPEP-NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVH 2840
Query: 328 LYVYDPP--TTIP 338
L + P TT+P
Sbjct: 2841 LTILVLPVFTTLP 2853
Score = 49.7 bits (117), Expect = 5e-06
Identities = 57/231 (24%), Positives = 90/231 (38%), Gaps = 16/231 (6%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAV-EGEEIEVNCTA 168
+T + DEGRY C ++ Q++ + V PP + + AV E +++ C A
Sbjct: 185 ITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEA 244
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTS-QLMLKVHKEDDGVPVICQVEHPAV 227
P I WFK L ++V +YT QL L + D C+ +
Sbjct: 245 RGV-PTPNITWFKDGALLPTSTKV-----VYTRGGRQLQLGRAQSSDAGVYTCKASN--A 296
Query: 228 TGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW----VRV 283
G + L+V P + P G + L C A G P P + +W + V
Sbjct: 297 VGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL-SWHHEGLPV 355
Query: 284 DDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+ G L + + + +G Y C AS+ G+A Y + V PP
Sbjct: 356 AESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 406
Score = 49.3 bits (116), Expect = 7e-06
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTWV---RVDDEMPQHA--VLSGPNLFINNLNKTDNGT 310
LT AL L CEA G P+P++V W ++D + Q A +L L + D+
Sbjct: 2493 LTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ 2551
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTT 346
+ C SN VG+AH Y + V+ PPT T T T
Sbjct: 2552 FECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVT 2587
Score = 48.5 bits (114), Expect = 1e-05
Identities = 58/228 (25%), Positives = 86/228 (37%), Gaps = 22/228 (9%)
Query: 118 DEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDT-AVEGEEIEVNCTAMASKPA 174
D G Y C+ Q + + VL PP L ++ + G ++E+ C + P
Sbjct: 98 DSGLYSCRAENQAGTAQRDFHLL-VLTPPSVLGAGAAQEVLGLAGADVELQCWT-SGVPT 155
Query: 175 TTIRWFKGNTELKGKS---EVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL 231
+ W K + +V+E + +T H D+G C PA G
Sbjct: 156 PQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGS-----HVGDEG-RYQCVAFSPA--GQQ 207
Query: 232 QTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA 291
L V P + + E ++L CEA G P P +TW + +P
Sbjct: 208 ARDFQLRVHAPPTIW-GSNETGEVAVMEDHLVQLLCEARGVPTP-NITWFKDGALLPTST 265
Query: 292 VL----SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
+ G L + +D G Y C+ASN VG A L VY PPT
Sbjct: 266 KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPT 313
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/344 (21%), Positives = 121/344 (35%), Gaps = 51/344 (14%)
Query: 18 AAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLL 77
AA+P G+ R L ++ + QN DV V+ G + + C+ ++
Sbjct: 2104 AASPAGVADRNFTLQVQVPPVLEPVEFQN----DVVVVRGSLVELPCEARGVPLPLVS-- 2157
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQ-ESYT 136
+ +D PL + + L V D G Y C ++ + +
Sbjct: 2158 -------WMKDGEPLLSQSLE------QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF 2204
Query: 137 TITVLVPPRNLMIDIQKDTAVE---GEEIEVNCTAMASKPATTIRWFKGN---TELKGKS 190
+TV+ PP + D + T + G +E+ C A + P I W K T L+ S
Sbjct: 2205 QLTVMEPPH--IEDSGQPTELSLTPGAPMELLCDAQGT-PQPNITWHKDGQALTRLENNS 2261
Query: 191 EVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMT 250
+V + D C E PA G ++ + VQ P + +
Sbjct: 2262 RAT--------------RVLRVRDAGLYTCLAESPA--GAIEKSFRVRVQAPPNI-VGPR 2304
Query: 251 YPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN----LFINNLNKT 306
P + L L C +P P +TW R + + A P L + L+
Sbjct: 2305 GPRFVVGLAPGQLVLECSVEAEPAP-KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA 2363
Query: 307 DNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTT 350
D+G Y C A N G + + ++ PT P + T
Sbjct: 2364 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT 2407
Score = 47.4 bits (111), Expect = 3e-05
Identities = 31/89 (34%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 265 LTCEAIGKPQPVMVTW----VRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVG 320
L C+A G P P +V+W V +D P+ +L +L I + D G Y C ASN G
Sbjct: 2410 LPCQADGVPAP-LVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG 2468
Query: 321 KAHSDYMLYVYDPPTTIPPPTTTTTTTTT 349
L V +PP P P+ T T T
Sbjct: 2469 SDRQGRDLRVLEPPAIAPSPSNLTLTAHT 2497
Score = 46.6 bits (109), Expect = 5e-05
Identities = 69/306 (22%), Positives = 117/306 (38%), Gaps = 54/306 (17%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
+TV EG +SC+ P + + +D +PL L + S+ + L
Sbjct: 890 LTVREGHPTRLSCECRGV---------PFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 940
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTT-ITVLVPPR-------NLMIDIQKDTAVEGEEIE 163
++ EG Y C+ S + V VPP+ + + +D +E
Sbjct: 941 GQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVAT---LE 997
Query: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI-CQV 222
N T KP T+ W + D V ++L L++ + + V Q
Sbjct: 998 CNATG---KPPPTVTWER---------------DGQPVGAELGLQLQNQGQSLHVERAQA 1039
Query: 223 EHPA--------VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTRE-GDALELTCEAIGKP 273
H + G + + L V P++ I PL +T L L CEA+G P
Sbjct: 1040 AHTGRYSCVAENLAGRAERKFELSVLVPPEL-IGDLDPLTNITAALHSPLTLLCEAMGIP 1098
Query: 274 QPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
P + W R ++ + + + G L + + D+G Y C ASN G+A ++ +
Sbjct: 1099 PPA-IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVE 1157
Query: 330 VYDPPT 335
V PP+
Sbjct: 1158 VLVPPS 1163
Score = 45.8 bits (107), Expect = 8e-05
Identities = 64/299 (21%), Positives = 114/299 (38%), Gaps = 41/299 (13%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT- 136
+P+ + + P+ +S L S L+ L + + G Y C + + P E+
Sbjct: 341 HPSPTLSWHHEGLPVAESNESRLETDGSVLR--LESPGEASSGLYSC-VASSPAGEAVLQ 397
Query: 137 -TITVLVPPRNLMID-IQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEE 194
++ V VPP+ L+ + + + T + G+ +E+ C A S P TI+W L+ EE
Sbjct: 398 YSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGS-PVPTIQW------LQNGRPAEE 450
Query: 195 WSDMYTVTSQLMLKV-HKEDDGVPVI-CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYP 252
+ + + L + H E D + CQ + A T + + + ++ P V
Sbjct: 451 LAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQ 510
Query: 253 LQGLTREGDALELTCEAI------GKPQPVMV-------------TWVRVDDEMPQHAVL 293
+ C+ P+P +V T + V +P
Sbjct: 511 YHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLP----- 565
Query: 294 SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTT 352
P L I ++ D G Y C A+N+ G++ + L V PP P P + T
Sbjct: 566 --PPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVT 622
Score = 45.1 bits (105), Expect = 1e-04
Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 11/138 (7%)
Query: 208 KVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTC 267
KV D+G+ + G + + L+V P + P+ E ++ L C
Sbjct: 572 KVDLRDEGIYTCAATN---LAGESKREVALKVLVPPNIE---PGPVNKAVLENASVTLEC 625
Query: 268 EAIGKPQPVMVTWVR----VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAH 323
A G P P V+W + V M + G L I +D G+YRC ASN+ G
Sbjct: 626 LASGVPPPD-VSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTE 684
Query: 324 SDYMLYVYDPPTTIPPPT 341
Y L V PP PP+
Sbjct: 685 LRYGLRVNVPPRITLPPS 702
Score = 41.6 bits (96), Expect = 0.001
Identities = 67/288 (23%), Positives = 108/288 (37%), Gaps = 49/288 (17%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAV-EGEEIEVNC 166
+ +T D G Y C + + ++ VLVPP D+++ V +G+ + C
Sbjct: 1126 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMC 1185
Query: 167 TAMASKPATTIRWFKGNTEL-KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHP 225
+ P + WFK L +G + H DGV + +
Sbjct: 1186 N-VTGHPQPKLTWFKDGRPLARGDAH------------------HISPDGVLLQVLQANL 1226
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREG--------------DALELTCEAIG 271
+ G+ V K + H Q++ L G + + L CEA+
Sbjct: 1227 SSAGHYSCIAANAVGEKTK-HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 1285
Query: 272 KPQPVMVTWVRVDDEMPQHA-----VLSGPN-LFINNLNKTDNGTYRCEASNIVGKAHSD 325
P P +TW++ D P A +L G + L I N K D G Y C +N +G+A +
Sbjct: 1286 FPSP-NITWMK--DGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1342
Query: 326 YMLYVYDPPTTI---PPPTTTTTTTTTTTTTILTIITDSRAGEEGSIR 370
Y + V PP+ P T + LT+ +S A +IR
Sbjct: 1343 YHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTIR 1390
Score = 38.9 bits (89), Expect = 0.009
Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 18/96 (18%)
Query: 260 GDALELTCEAIGKPQPVMVT-----------------WVRVDDEMPQHAVLS-GPNLFIN 301
G +L L C+A G P P +V W ++ H +L G +L
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92
Query: 302 NLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
+ + D+G Y C A N G A D+ L V PP+ +
Sbjct: 93 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVL 128
Score = 37.0 bits (84), Expect = 0.036
Identities = 37/162 (22%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 85 YFRDFRPLKDS--RFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLV 142
+ +D PL+ S R QL N S +++ D GRY C + I VL
Sbjct: 2970 WIKDGLPLRGSHLRHQLQNGS-----LTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQ 3024
Query: 143 PPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
++ Q T G+++ + C A +P TI W + L+ + D
Sbjct: 3025 SAPVFQVEPQDMTVRSGDDVALRCQA-TGEPTPTIEWLQAGQPLRASRRLRTLPD----- 3078
Query: 203 SQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
L L+ + D C + + G+ + +L V+ +PQ
Sbjct: 3079 GSLWLENVETGDAGTYDCVAHN--LLGSATARAFLVVRGEPQ 3118
Score = 33.1 bits (74), Expect = 0.52
Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 5/81 (6%)
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVG 320
LTC + G P P V+W + ++ + V L I G Y C A N G
Sbjct: 2594 LTCHSTGIPAPT-VSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 2652
Query: 321 KAHSDYMLYVYDPPTTIPPPT 341
AH L V P P P+
Sbjct: 2653 VAHKHVFLTVQASPVVKPLPS 2673
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 75.5 bits (184), Expect = 9e-14
Identities = 80/308 (25%), Positives = 134/308 (43%), Gaps = 42/308 (13%)
Query: 39 IPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI-YFRDFRPLKD 94
+P G F K +VTV +GE AT+ C + D+ V ++ NR TI Y + + D
Sbjct: 29 VPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTILYAGNDKWCLD 85
Query: 95 SRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVPPRNLMIDIQK 153
R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V P+ +++I
Sbjct: 86 PRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPK--IVEISS 143
Query: 154 DTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVH-- 210
D ++ EG I + C A +P T+ W + + G +E+ ++ +T +
Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECS 202
Query: 211 -KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TREGDALELTCE 268
D PV+ +V+ + V Y P + +G G L CE
Sbjct: 203 ASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVPVGQKGTLQCE 244
Query: 269 AIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTYRCEASNIVGK 321
A P W + D + + V + P L N+++ D G Y C ASN +G
Sbjct: 245 ASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGH 303
Query: 322 AHSDYMLY 329
++ ML+
Sbjct: 304 TNASIMLF 311
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 75.1 bits (183), Expect = 1e-13
Identities = 66/286 (23%), Positives = 116/286 (40%), Gaps = 22/286 (7%)
Query: 79 PNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTI 138
P+ ++ +D P+ + L ++L + SD GRY C + ++ +
Sbjct: 814 PSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVV 873
Query: 139 TVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDM 198
+ P +++ + + V E + + C + A P + W+K L+ + V +D
Sbjct: 874 LQVHMPPSILGEELNVSVVANESVALECQSHAMPPPV-LSWWKDGRPLEPRPGVHLSAD- 931
Query: 199 YTVTSQLMLKVHKED--DGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL 256
+ +L+V + D D C+ + A G + L V P ++ ++ L
Sbjct: 932 -----KALLQVDRADVWDAGHYTCEALNQA--GRSEKHYNLNVWVAPVFPLRESHTLT-- 982
Query: 257 TREGDALELTCEAIGKPQPVMVTWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGT 310
REG L+CE G P P ++W + +P QH G L++ GT
Sbjct: 983 VREGHPTSLSCECRGVPFP-KISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 1041
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPP--PTTTTTTTTTTTTTI 354
Y CE SN+VG + D L V+ PP P P T + T+
Sbjct: 1042 YTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATL 1087
Score = 74.3 bits (181), Expect = 2e-13
Identities = 86/313 (27%), Positives = 122/313 (38%), Gaps = 32/313 (10%)
Query: 42 GDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS-RFQLL 100
GD + L ++VTV ++ C L NP + ++ P S R Q+L
Sbjct: 1655 GDTEEL-VEEVTVNASSTVSLQCPA---------LGNPVPTISWLQNGLPFSPSPRLQVL 1704
Query: 101 NFSSSELKVSLTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNLMIDIQKDTAVEG 159
L+VS V+ D Y C E T+ V VPPR +D+++ TA+
Sbjct: 1705 E-DGQVLQVSTAEVA--DAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILN 1761
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ + C A P + W+K + L EV + T L L + D
Sbjct: 1762 SSVSLPCDVHAH-PNPEVTWYKDSQALSLGEEVF----LLPGTHTLQLGRARLSDSGMYT 1816
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQG-LTREGDALELTCEAIGKPQPVMV 278
C+ + A G Q L V P P L R GD L+CE P+P V
Sbjct: 1817 CEALNAA--GRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPT-V 1873
Query: 279 TWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
TW + D P A+ G L I +D G Y C+ SN+ G+A + L V
Sbjct: 1874 TWYK--DGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQV 1931
Query: 333 PPTTIPPPTTTTT 345
PPT P T T +
Sbjct: 1932 PPTFENPKTETVS 1944
Score = 73.2 bits (178), Expect = 5e-13
Identities = 74/305 (24%), Positives = 121/305 (39%), Gaps = 21/305 (6%)
Query: 33 FSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL 92
F A L+ + ++ V+EG+ + C+ + P + +D PL
Sbjct: 2017 FVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQ---------PPPDVAWLKDGSPL 2067
Query: 93 KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDI 151
L F + L + SD G Y C + +++ T+ VLVPP
Sbjct: 2068 GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 2127
Query: 152 QKDTAVE--GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKV 209
T V GE + + C S P + W K L +T+ + KV
Sbjct: 2128 GSGTLVSRPGELVTMVCPVRGSPPIH-VSWLKDGLPLPLSQRTLLHGSGHTLR---ISKV 2183
Query: 210 HKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEA 269
D G+ C PA G L+VQ P + + + + G +EL CEA
Sbjct: 2184 QLADAGI-FTCVAASPA--GVADRNFTLQVQVPPVLE-PVEFQNDVVVVRGSLVELPCEA 2239
Query: 270 IGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
G P P +V+W++ + + ++ GP+L + + D+GTY C A + G+A + L
Sbjct: 2240 RGVPLP-LVSWMKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT 2298
Query: 330 VYDPP 334
V +PP
Sbjct: 2299 VMEPP 2303
Score = 69.3 bits (168), Expect = 7e-12
Identities = 78/314 (24%), Positives = 116/314 (36%), Gaps = 28/314 (8%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVS 110
+V+V+ E + CQ + V+ +++D RPL+ ++ S+ + +
Sbjct: 888 NVSVVANESVALECQSHAMPPPVLS---------WWKDGRPLEPRPG--VHLSADKALLQ 936
Query: 111 LTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ + D G Y C+ + E + + V V P + + T EG ++C
Sbjct: 937 VDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECR 996
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
P I W K L G E + V L L + C+ + V G
Sbjct: 997 GV-PFPKISWRKDGQPLPG--EGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSN--VVG 1051
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ 289
N LEV PQ+ P Q + L C A GKP P VTW R D P
Sbjct: 1052 NSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPT-VTWER--DGQPV 1108
Query: 290 HAVLS------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP--PPT 341
A L G +L + G Y C A N+ G+A + L V PP I P
Sbjct: 1109 GAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPL 1168
Query: 342 TTTTTTTTTTTTIL 355
T T + T+L
Sbjct: 1169 TNITAALHSPLTLL 1182
Score = 61.2 bits (147), Expect = 2e-09
Identities = 59/239 (24%), Positives = 101/239 (42%), Gaps = 24/239 (10%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTIT--VLVPPRNLMIDIQKDTAVEGEEIEVNC 166
+ + V + DEG Y C T+ ES + VLVPP N+ +E + + C
Sbjct: 659 LQIEKVDLRDEGIYTCAA-TNLAGESKREVALKVLVPP-NIEPGPVNKAVLENASVTLEC 716
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKED--DGVPVICQVEH 224
A + P + WFKG+ V W + +L++ + D C +
Sbjct: 717 LA-SGVPPPDVSWFKGH------QPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASN 769
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
V G+ + + L V P++ + + P G + LTC A G P P ++ W++
Sbjct: 770 --VAGSTELRYGLRVNVPPRITLPPSLP--GPVLVNTPVRLTCNATGAPSPTLM-WLKDG 824
Query: 285 DEM-----PQHAVLSGPN-LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI 337
+ + P V G L + + +D+G Y C A + VG+ D +L V+ PP+ +
Sbjct: 825 NPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL 883
Score = 60.5 bits (145), Expect = 3e-09
Identities = 70/317 (22%), Positives = 127/317 (40%), Gaps = 36/317 (11%)
Query: 33 FSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL 92
FS L+P + + V++G+ A + C V +P + +F+D RPL
Sbjct: 1245 FSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTG---------HPQPKLTWFKDGRPL 1295
Query: 93 KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQES-YTTITVLVPPRNLMIDI 151
+R + S + + + ++S G Y C +++ + ++VL+ P ++
Sbjct: 1296 --ARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPT--ILGG 1351
Query: 152 QKDTAVEGEEIEVN------CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQL 205
+D+A E + VN C A+A P+ I W K + ++ + +
Sbjct: 1352 AEDSADEEVTVTVNNPISLICEALAF-PSPNITWMKDGAPFEASRNIQLLPGTHGLQ--- 1407
Query: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL----TREGD 261
+L KED G C V + G ++EV P + G+ T+
Sbjct: 1408 ILNAQKEDAG-QYTCVVTNEL--GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNS 1464
Query: 262 ALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS----GPNLFINNLNKTDNGTYRCEASN 317
L L CE+ P P + W + + + L G L I +D+G Y C A+N
Sbjct: 1465 TLTLECESWAVPPPT-IRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATN 1523
Query: 318 IVGKAHSDYMLYVYDPP 334
+ G+ D+ + + PP
Sbjct: 1524 VAGEDDQDFNVLIQVPP 1540
Score = 60.5 bits (145), Expect = 3e-09
Identities = 68/300 (22%), Positives = 120/300 (40%), Gaps = 23/300 (7%)
Query: 45 QNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSS 104
+N T+ V+ + G ++C V+ P + +D P++ S S
Sbjct: 1936 ENPKTETVSQVAGSPLVLTCDVSGV---------PAPTVTWLKDRMPVESSAVH--GVVS 1984
Query: 105 SELKVSLTNVSISDEGRYFCQLY-TDPPQESYTTITVLVPPRNLMIDIQKDTAV-EGEEI 162
++ L+ + + G Y C T + VLV PR + ++ V EG+E+
Sbjct: 1985 RGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEV 2044
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
++C A +P + W K + L ++ Y L+LK + D C
Sbjct: 2045 RLDCEA-DGQPPPDVAWLKDGSPLG--QDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVA 2101
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
+PA G + V P + ++R G+ + + C G P P+ V+W++
Sbjct: 2102 HNPA--GEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSP-PIHVSWLK 2158
Query: 283 VDDEMP--QHAVL--SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIP 338
+P Q +L SG L I+ + D G + C A++ G A ++ L V PP P
Sbjct: 2159 DGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEP 2218
Score = 60.1 bits (144), Expect = 4e-09
Identities = 77/300 (25%), Positives = 121/300 (40%), Gaps = 45/300 (15%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLK-DSRFQLLNFSSSELKVS 110
V V G+ A +SC+ + P +++D +PL R Q L ++
Sbjct: 1851 VLVRVGDKAVLSCETDAL---------PEPTVTWYKDGQPLVLAQRTQALRGGQ---RLE 1898
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ +SD+G Y C++ + T T+TV VPP + + V G + + C +
Sbjct: 1899 IQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCD-V 1957
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ---LMLKVHKEDDGVPVICQVEHPA 226
+ PA T+ W LK + VE S ++ V S+ L L + C E+
Sbjct: 1958 SGVPAPTVTW------LKDRMPVES-SAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN-- 2008
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE-----LTCEAIGKPQPVMVTWV 281
TQ + V + G+ RE LE L CEA G+P P V W+
Sbjct: 2009 ------TQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPD-VAWL 2061
Query: 282 R----VDDEMPQHA--VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPT 335
+ + +M H L G +L + L +D G Y C A N G+ + + V PPT
Sbjct: 2062 KDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPT 2121
Score = 57.8 bits (138), Expect = 2e-08
Identities = 76/312 (24%), Positives = 120/312 (38%), Gaps = 37/312 (11%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPL-KDSRFQLLNFSSSELKVS 110
V+V++ VAT+ C P + RD +P+ + QL N S +
Sbjct: 1077 VSVVQDGVATLECNATGK---------PPPTVTWERDGQPVGAELGLQLQNQGQS---LH 1124
Query: 111 LTNVSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNL--MIDIQKDTAVEGEEIEVNCT 167
+ + GRY C + E ++VLVPP + + + TA + + C
Sbjct: 1125 VERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCE 1184
Query: 168 AMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHK--EDDGVPVICQVEHP 225
AM P IRWF+G + V D Y + MLK+ + E D C +
Sbjct: 1185 AMGIPPPA-IRWFRG------EEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNE 1237
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTR--EGDALELTCEAIGKPQPVMVTWVRV 283
A G + +EV P + + L+ + + +G L C G PQP + TW +
Sbjct: 1238 A--GEARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKL-TWFKD 1291
Query: 284 DDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPP 339
+ + H G L + N + G Y C A+N VG+ + L V PT +
Sbjct: 1292 GRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGG 1351
Query: 340 PTTTTTTTTTTT 351
+ T T
Sbjct: 1352 AEDSADEEVTVT 1363
Score = 56.6 bits (135), Expect = 4e-08
Identities = 86/335 (25%), Positives = 130/335 (38%), Gaps = 41/335 (12%)
Query: 9 GSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNK 68
G + A +P G + R L A PT G N T +V V+E + + C+
Sbjct: 282 GDEGRYQCVAFSPAGQQARDFQLRVHAP---PTIWGSNE-TGEVAVMEDHLVQLLCEARG 337
Query: 69 SDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT 128
P +F+D L S + +L+ L SD G Y C+
Sbjct: 338 V---------PTPNITWFKDGALLPTSTKVVYTRGGRQLQ--LGRAQSSDAGVYTCKASN 386
Query: 129 DP-PQESYTTITVLVPP-------RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
E T + V VPP R ++ AV G + + C A P+ T+ W
Sbjct: 387 AVGAAEKATRLDVYVPPTIEGAGGRPYVVK-----AVAGRPVALECVARGH-PSPTLSWH 440
Query: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
+ +E S + T S L L+ E C PA G Q +EVQ
Sbjct: 441 HEGLPVAESNE----SRLETDGSVLRLESPGEASSGLYSCVASSPA--GEAVLQYSVEVQ 494
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWV---RVDDEMPQHAVLS-GP 296
PQ+ + Q T G LEL C+A G P P + W+ R +E+ V S G
Sbjct: 495 VPPQLLVAEGLG-QVTTIVGQPLELPCQASGSPVPT-IQWLQNGRPAEELAGVQVASQGT 552
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
L I+++ +G + C+A+N G A ++ + V+
Sbjct: 553 TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 587
Score = 52.0 bits (123), Expect = 1e-06
Identities = 60/233 (25%), Positives = 92/233 (39%), Gaps = 21/233 (9%)
Query: 108 KVSLTNVSISDEGRYFCQLYTDPPQE-SYTTITVLVPP--RNLMIDIQKDTAVEGEEIEV 164
++ + + S D G Y C T + V VPP N + D+ + EG +
Sbjct: 2810 QLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDL---STTEGSHAFL 2866
Query: 165 NCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEH 224
C A S P I W K + G E + +L++K + D C E+
Sbjct: 2867 PCKARGS-PEPNITWDKDGQPVSGA----EGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 2921
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
G + + +L + P + T P R GD L L C A G P P + W V+
Sbjct: 2922 --AVGRARRRVHLTILVLP---VFTTLPGDRSLRLGDRLWLRCAARGSPTP-RIGWT-VN 2974
Query: 285 DEMPQHAVLS---GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
D V G L +++ D+GTY C A N VG+ + ++V + P
Sbjct: 2975 DRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 3027
Score = 51.2 bits (121), Expect = 2e-06
Identities = 77/349 (22%), Positives = 135/349 (38%), Gaps = 47/349 (13%)
Query: 38 LIPT--GDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS 95
L PT G ++ ++VTV ++ C+ L P+ + +D P + S
Sbjct: 1344 LAPTILGGAEDSADEEVTVTVNNPISLICEA---------LAFPSPNITWMKDGAPFEAS 1394
Query: 96 R-FQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT--ITVLVPPRNLMIDIQ 152
R QLL + + + N D G+Y C + T+ E+ + VL+PP D
Sbjct: 1395 RNIQLLPGTHG---LQILNAQKEDAGQYTC-VVTNELGEAVKNYHVEVLIPPSISKDDPL 1450
Query: 153 KDTAVEGEEIEVNCTAMA-----SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLML 207
+ V+ + +VN T + P TIRW+K + S ++ + L +
Sbjct: 1451 GEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE----GRLLQI 1506
Query: 208 KVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDA----- 262
+ + D +C + A + ++V Q + + L+RE +A
Sbjct: 1507 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVT 1566
Query: 263 ----------LELTCEAIGKPQPVMVTWVRVDDEMP---QHAVLSGPNLFINNLNKTDN- 308
L C+ P P + TW R D + + +VL G + L + +N
Sbjct: 1567 EYREIVENNPAYLYCDTNAIPPPDL-TWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENA 1625
Query: 309 GTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTI 357
G Y C+ASN VG+ Y L V PP + T ++ +++
Sbjct: 1626 GRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSL 1674
Score = 51.2 bits (121), Expect = 2e-06
Identities = 55/193 (28%), Positives = 78/193 (40%), Gaps = 26/193 (13%)
Query: 156 AVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDG 215
AV EE+ + C A + P TI W K +G + S QL + +D
Sbjct: 2768 AVAEEEVLLPCEA-SGIPRPTITWQK-----EGLNVATGVSTQVLPGGQLRIAHASPEDA 2821
Query: 216 VPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL----TREGDALELTCEAIG 271
+C ++ A G+ + L VQ P + GL T EG L C+A G
Sbjct: 2822 GNYLCIAKNSA--GSAMGKTRLVVQVPPVIE-------NGLPDLSTTEGSHAFLPCKARG 2872
Query: 272 KPQPVMVTWVR----VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYM 327
P+P +TW + V + + L + NL D GTY C A N VG+A
Sbjct: 2873 SPEP-NITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVH 2931
Query: 328 LYVYDPP--TTIP 338
L + P TT+P
Sbjct: 2932 LTILVLPVFTTLP 2944
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/179 (24%), Positives = 71/179 (39%), Gaps = 15/179 (8%)
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
G I+++C P I W K L+G + + L + + DD
Sbjct: 3042 GGSIQLDCVVRGD-PVPDIHWIKDGLPLRGSHLRHQLQN-----GSLTIHRTERDDAGRY 3095
Query: 219 ICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMV 278
C E+ G + L +Q P ++ P R GD + L C+A G+P P +
Sbjct: 3096 QCLAENEM--GVAKKVVILVLQSAPVFQVE---PQDMTVRSGDDVALRCQATGEPTPT-I 3149
Query: 279 TWVRVDDEMPQHA---VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
W++ + L +L++ N+ D GTY C A N++G A + L V P
Sbjct: 3150 EWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEP 3208
Score = 49.7 bits (117), Expect = 5e-06
Identities = 57/231 (24%), Positives = 90/231 (38%), Gaps = 16/231 (6%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAV-EGEEIEVNCTA 168
+T + DEGRY C ++ Q++ + V PP + + AV E +++ C A
Sbjct: 276 ITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEA 335
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTS-QLMLKVHKEDDGVPVICQVEHPAV 227
P I WFK L ++V +YT QL L + D C+ +
Sbjct: 336 RGV-PTPNITWFKDGALLPTSTKV-----VYTRGGRQLQLGRAQSSDAGVYTCKASN--A 387
Query: 228 TGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW----VRV 283
G + L+V P + P G + L C A G P P + +W + V
Sbjct: 388 VGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL-SWHHEGLPV 446
Query: 284 DDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPP 334
+ G L + + + +G Y C AS+ G+A Y + V PP
Sbjct: 447 AESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 497
Score = 49.3 bits (116), Expect = 7e-06
Identities = 34/96 (35%), Positives = 47/96 (48%), Gaps = 6/96 (6%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTWV---RVDDEMPQHA--VLSGPNLFINNLNKTDNGT 310
LT AL L CEA G P+P++V W ++D + Q A +L L + D+
Sbjct: 2584 LTAHTPAL-LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ 2642
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTT 346
+ C SN VG+AH Y + V+ PPT T T T
Sbjct: 2643 FECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVT 2678
Score = 47.4 bits (111), Expect = 3e-05
Identities = 69/306 (22%), Positives = 118/306 (38%), Gaps = 54/306 (17%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
+TV EG ++SC+ P + + +D +PL L + S+ + L
Sbjct: 981 LTVREGHPTSLSCECRGV---------PFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYL 1031
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTT-ITVLVPPR-------NLMIDIQKDTAVEGEEIE 163
++ EG Y C+ S + V VPP+ + + +D +E
Sbjct: 1032 GQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVAT---LE 1088
Query: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI-CQV 222
N T KP T+ W + D V ++L L++ + + V Q
Sbjct: 1089 CNATG---KPPPTVTWER---------------DGQPVGAELGLQLQNQGQSLHVERAQA 1130
Query: 223 EHPA--------VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTRE-GDALELTCEAIGKP 273
H + G + + L V P++ I PL +T L L CEA+G P
Sbjct: 1131 AHTGRYSCVAENLAGRAERKFELSVLVPPEL-IGDLDPLTNITAALHSPLTLLCEAMGIP 1189
Query: 274 QPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
P + W R ++ + + + G L + + D+G Y C ASN G+A ++ +
Sbjct: 1190 PPA-IRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVE 1248
Query: 330 VYDPPT 335
V PP+
Sbjct: 1249 VLVPPS 1254
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/344 (21%), Positives = 121/344 (35%), Gaps = 51/344 (14%)
Query: 18 AAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLL 77
AA+P G+ R L ++ + QN DV V+ G + + C+ ++
Sbjct: 2195 AASPAGVADRNFTLQVQVPPVLEPVEFQN----DVVVVRGSLVELPCEARGVPLPLVS-- 2248
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQ-ESYT 136
+ +D PL + + L V D G Y C ++ + +
Sbjct: 2249 -------WMKDGEPLLSQSLE------QGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHF 2295
Query: 137 TITVLVPPRNLMIDIQKDTAVE---GEEIEVNCTAMASKPATTIRWFKGN---TELKGKS 190
+TV+ PP + D + T + G +E+ C A + P I W K T L+ S
Sbjct: 2296 QLTVMEPPH--IEDSGQPTELSLTPGAPMELLCDAQGT-PQPNITWHKDGQALTRLENNS 2352
Query: 191 EVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMT 250
+V + D C E PA G ++ + VQ P + +
Sbjct: 2353 RAT--------------RVLRVRDAGLYTCLAESPA--GAIEKSFRVRVQAPPNI-VGPR 2395
Query: 251 YPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN----LFINNLNKT 306
P + L L C +P P +TW R + + A P L + L+
Sbjct: 2396 GPRFVVGLAPGQLVLECSVEAEPAP-KITWHRDGIVLQEDAHTQFPERGRFLQLQALSTA 2454
Query: 307 DNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTT 350
D+G Y C A N G + + ++ PT P + T
Sbjct: 2455 DSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQT 2498
Score = 47.4 bits (111), Expect = 3e-05
Identities = 31/89 (34%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 265 LTCEAIGKPQPVMVTW----VRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVG 320
L C+A G P P +V+W V +D P+ +L +L I + D G Y C ASN G
Sbjct: 2501 LPCQADGVPAP-LVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG 2559
Query: 321 KAHSDYMLYVYDPPTTIPPPTTTTTTTTT 349
L V +PP P P+ T T T
Sbjct: 2560 SDRQGRDLRVLEPPAIAPSPSNLTLTAHT 2588
Score = 47.0 bits (110), Expect = 3e-05
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 6/74 (8%)
Query: 267 CEAIGKPQPVMVTWVRVDDEMPQH-----AVLSGPNLFINNLNKTDNGTYRCEASNIVGK 321
C G P+P VTW + P H AVL +LF+ +++ D+G Y C+A+N VG
Sbjct: 24 CGTHGTPKP-QVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGS 82
Query: 322 AHSDYMLYVYDPPT 335
L VY PP+
Sbjct: 83 TSRRAKLVVYVPPS 96
Score = 47.0 bits (110), Expect = 3e-05
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVL----SGPNLFINNLNKTDNGTYRCE 314
E ++L CEA G P P +TW + +P + G L + +D G Y C+
Sbjct: 325 EDHLVQLLCEARGVPTP-NITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCK 383
Query: 315 ASNIVGKAHSDYMLYVYDPPT 335
ASN VG A L VY PPT
Sbjct: 384 ASNAVGAAEKATRLDVYVPPT 404
Score = 45.8 bits (107), Expect = 8e-05
Identities = 64/299 (21%), Positives = 114/299 (38%), Gaps = 41/299 (13%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT- 136
+P+ + + P+ +S L S L+ L + + G Y C + + P E+
Sbjct: 432 HPSPTLSWHHEGLPVAESNESRLETDGSVLR--LESPGEASSGLYSC-VASSPAGEAVLQ 488
Query: 137 -TITVLVPPRNLMID-IQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEE 194
++ V VPP+ L+ + + + T + G+ +E+ C A S P TI+W L+ EE
Sbjct: 489 YSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGS-PVPTIQW------LQNGRPAEE 541
Query: 195 WSDMYTVTSQLMLKV-HKEDDGVPVI-CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYP 252
+ + + L + H E D + CQ + A T + + + ++ P V
Sbjct: 542 LAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQ 601
Query: 253 LQGLTREGDALELTCEAI------GKPQPVMV-------------TWVRVDDEMPQHAVL 293
+ C+ P+P +V T + V +P
Sbjct: 602 YHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLP----- 656
Query: 294 SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTT 352
P L I ++ D G Y C A+N+ G++ + L V PP P P + T
Sbjct: 657 --PPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVT 713
Score = 45.1 bits (105), Expect = 1e-04
Identities = 39/138 (28%), Positives = 56/138 (40%), Gaps = 11/138 (7%)
Query: 208 KVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTC 267
KV D+G+ + G + + L+V P + P+ E ++ L C
Sbjct: 663 KVDLRDEGIYTCAATN---LAGESKREVALKVLVPPNIE---PGPVNKAVLENASVTLEC 716
Query: 268 EAIGKPQPVMVTWVR----VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAH 323
A G P P V+W + V M + G L I +D G+YRC ASN+ G
Sbjct: 717 LASGVPPPD-VSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTE 775
Query: 324 SDYMLYVYDPPTTIPPPT 341
Y L V PP PP+
Sbjct: 776 LRYGLRVNVPPRITLPPS 793
Score = 41.2 bits (95), Expect = 0.002
Identities = 59/250 (23%), Positives = 96/250 (38%), Gaps = 46/250 (18%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYT-TITVLVPPRNLMIDIQKDTAV-EGEEIEVNC 166
+ +T D G Y C + + ++ VLVPP D+++ V +G+ + C
Sbjct: 1217 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMC 1276
Query: 167 TAMASKPATTIRWFKGNTEL-KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHP 225
+ P + WFK L +G + H DGV + +
Sbjct: 1277 N-VTGHPQPKLTWFKDGRPLARGDAH------------------HISPDGVLLQVLQANL 1317
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREG--------------DALELTCEAIG 271
+ G+ V K + H Q++ L G + + L CEA+
Sbjct: 1318 SSAGHYSCIAANAVGEKTK-HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALA 1376
Query: 272 KPQPVMVTWVRVDDEMPQHA-----VLSGPN-LFINNLNKTDNGTYRCEASNIVGKAHSD 325
P P +TW++ D P A +L G + L I N K D G Y C +N +G+A +
Sbjct: 1377 FPSP-NITWMK--DGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1433
Query: 326 YMLYVYDPPT 335
Y + V PP+
Sbjct: 1434 YHVEVLIPPS 1443
Score = 36.6 bits (83), Expect = 0.047
Identities = 37/162 (22%), Positives = 63/162 (38%), Gaps = 15/162 (9%)
Query: 85 YFRDFRPLKDS--RFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLV 142
+ +D PL+ S R QL N S +++ D GRY C + I VL
Sbjct: 3061 WIKDGLPLRGSHLRHQLQNGS-----LTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ 3115
Query: 143 PPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
++ Q T G+++ + C A +P TI W + L+ + D
Sbjct: 3116 SAPVFQVEPQDMTVRSGDDVALRCQA-TGEPTPTIEWLQAGQPLRASRRLRTLPD----- 3169
Query: 203 SQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
L L+ + D C + + G+ + +L V+ +PQ
Sbjct: 3170 GSLWLENVETGDAGTYDCVAHN--LLGSATARAFLVVRGEPQ 3209
Score = 35.4 bits (80), Expect = 0.10
Identities = 42/174 (24%), Positives = 68/174 (39%), Gaps = 17/174 (9%)
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKT---------DNGT 310
G +EL C G P P V W + D P + GP+L + + D G
Sbjct: 232 GADVELQCWTSGVPTP-QVEWTK--DRQP--VLPGGPHLQVQEDGQVLRITGSHVGDEGR 286
Query: 311 YRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITDSRAGEEGSIR 370
Y+C A + G+ D+ L V+ PPT + T ++ ++ ++R +I
Sbjct: 287 YQCVAFSPAGQQARDFQLRVHAPPTIW--GSNETGEVAVMEDHLVQLLCEARGVPTPNIT 344
Query: 371 AVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAI 424
+ VV+ + LGR + G Y T +A A AA+ T +
Sbjct: 345 WFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVY-TCKASNAVGAAEKATRL 397
Score = 33.1 bits (74), Expect = 0.52
Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 5/81 (6%)
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVG 320
LTC + G P P V+W + ++ + V L I G Y C A N G
Sbjct: 2685 LTCHSTGIPAPT-VSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 2743
Query: 321 KAHSDYMLYVYDPPTTIPPPT 341
AH L V P P P+
Sbjct: 2744 VAHKHVFLTVQASPVVKPLPS 2764
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 74.7 bits (182), Expect = 2e-13
Identities = 80/309 (25%), Positives = 129/309 (41%), Gaps = 50/309 (16%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVS 110
DV V GE A + CQ + TIY++ + D + + ++ +L +S
Sbjct: 157 DVVVAAGEPAILECQPPRGHPE---------PTIYWKKDKVRIDDKEERISIRGGKLMIS 207
Query: 111 LTNVSISDEGRYFC-------QLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIE 163
N SD G Y C + +DP + +TV P L I + +E E +E
Sbjct: 208 --NTRKSDAGMYTCVGTNMVGERDSDPAE-----LTVFERPTFLRRPINQ-VVLEEEAVE 259
Query: 164 VNCTAMASKPATTIRWFKGNTEL-KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
C P T+RW K + +L +G+ +++ D YT+ + K D+G +C
Sbjct: 260 FRCQVQGD-PQPTVRWKKDDADLPRGRYDIK---DDYTLRIK---KTMSTDEGT-YMCIA 311
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
E+ G ++ L V+ PQ ++ P + +G + CE G PQP V W +
Sbjct: 312 ENRV--GKMEASATLTVRAPPQFVVR---PRDQIVAQGRTVTFPCETKGNPQPA-VFWQK 365
Query: 283 VDDE------MPQH-----AVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
+ PQ +V +L I N+ ++D G Y C+A + G + L V
Sbjct: 366 EGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVT 425
Query: 332 DPPTTIPPP 340
D T PPP
Sbjct: 426 DVLTDRPPP 434
Score = 63.9 bits (154), Expect = 3e-10
Identities = 74/311 (23%), Positives = 115/311 (36%), Gaps = 26/311 (8%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVS 110
DV V +GE T++C+ I+ + +D + R L + S L++
Sbjct: 55 DVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKD--DPRSHRMLLPSGSLFFLRIV 112
Query: 111 LTNVSISDEGRYFC--QLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTA 168
S DEG Y C + Y ++ V + + + GE + C
Sbjct: 113 HGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQP 172
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVT 228
P TI W K + K E + +LM+ ++ D C V
Sbjct: 173 PRGHPEPTIYWKKDKVRIDDKEE-----RISIRGGKLMISNTRKSDAGMYTC------VG 221
Query: 229 GNLQTQR-----YLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRV 283
N+ +R L V +P + P+ + E +A+E C+ G PQP V W +
Sbjct: 222 TNMVGERDSDPAELTVFERPTF---LRRPINQVVLEEEAVEFRCQVQGDPQPT-VRWKKD 277
Query: 284 DDEMPQ--HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPT 341
D ++P+ + + L I TD GTY C A N VGK + L V PP + P
Sbjct: 278 DADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPR 337
Query: 342 TTTTTTTTTTT 352
T T
Sbjct: 338 DQIVAQGRTVT 348
Score = 58.9 bits (141), Expect = 9e-09
Identities = 76/324 (23%), Positives = 130/324 (40%), Gaps = 42/324 (12%)
Query: 54 VIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTN 113
V+E E CQV ++ + +D L R+ + + + +K +++
Sbjct: 252 VLEEEAVEFRCQVQGDPQPTVR---------WKKDDADLPRGRYDIKDDYTLRIKKTMS- 301
Query: 114 VSISDEGRYFCQLYTDPPQ-ESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASK 172
+DEG Y C + E+ T+TV PP+ ++ + +G + C +
Sbjct: 302 ---TDEGTYMCIAENRVGKMEASATLTVRAPPQ-FVVRPRDQIVAQGRTVTFPCETKGN- 356
Query: 173 PATTIRWFK-GNTELKGKSEVEEWSDMYTV--TSQLMLKVHKEDDGVPVICQVEHPAVTG 229
P + W K G+ L ++ ++ + +V T L + + D ICQ V G
Sbjct: 357 PQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQAL--TVAG 414
Query: 230 NLQTQRYLEVQY----KPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR--- 282
++ + LEV +P I Q L +G AL L C+A G P PV ++W++
Sbjct: 415 SILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTAL-LKCKATGDPLPV-ISWLKEGF 472
Query: 283 -VDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTI---- 337
P+ + L I NL +D GTY C A++ G+ +L V + TI
Sbjct: 473 TFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNY 532
Query: 338 -------PPPTTTTTTTTTTTTTI 354
PP T T + T+
Sbjct: 533 DLSDLPGPPSKPQVTDVTKNSVTL 556
Score = 51.6 bits (122), Expect = 1e-06
Identities = 61/214 (28%), Positives = 94/214 (43%), Gaps = 28/214 (13%)
Query: 143 PPRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTV 201
PPR +++ D V +GE +NC A +P TI W+K ++ + M
Sbjct: 46 PPR--IVEHPSDVIVSKGEPTTLNCKA-EGRPTPTIEWYKDGERVETDKDDPRSHRMLLP 102
Query: 202 TSQLMLK--VH----KEDDGVPVICQVEH---PAVTGNLQTQRYLEVQYKPQVHIQMTYP 252
+ L VH K D+G +C + AV+ N LEV Q P
Sbjct: 103 SGSLFFLRIVHGRRSKPDEG-SYVCVARNYLGEAVSRNAS----LEVALLRDDFRQN--P 155
Query: 253 LQGLTREGDALELTCEAI-GKPQPVMVTW----VRVDDEMPQHAVLSGPNLFINNLNKTD 307
+ G+ L C+ G P+P + W VR+DD+ + ++ G L I+N K+D
Sbjct: 156 TDVVVAAGEPAILECQPPRGHPEPT-IYWKKDKVRIDDKEERISIRGG-KLMISNTRKSD 213
Query: 308 NGTYRCEASNIVGKAHSD-YMLYVYDPPTTIPPP 340
G Y C +N+VG+ SD L V++ PT + P
Sbjct: 214 AGMYTCVGTNMVGERDSDPAELTVFERPTFLRRP 247
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,745,416
Number of Sequences: 37866
Number of extensions: 815373
Number of successful extensions: 9887
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 204
Number of HSP's successfully gapped in prelim test: 261
Number of HSP's that attempted gapping in prelim test: 4868
Number of HSP's gapped (non-prelim): 4061
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.