Search of human proteins with 148539842

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148539842 deleted in malignant brain tumors 1 isoform b
precursor [Homo sapiens]
         (2413 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148539842 deleted in malignant brain tumors 1 isoform b precu...  5200   0.0  
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...  5170   0.0  
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...  3482   0.0  
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]    3425   0.0  
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]    3200   0.0  
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...  1101   0.0  
gi|44889963 CD163 antigen isoform b [Homo sapiens]                    901   0.0  
gi|44662834 CD163 antigen isoform a [Homo sapiens]                    901   0.0  
gi|18152779 scavenger receptor cysteine rich domain containing, ...   515   e-145
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]            491   e-138
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]           474   e-133
gi|4506143 neurotrypsin precursor [Homo sapiens]                      371   e-102
gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]      296   1e-79
gi|5174411 CD5 molecule-like [Homo sapiens]                           276   1e-73
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]             271   7e-72
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]              267   8e-71
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]             264   7e-70
gi|194018748 CD6 molecule [Homo sapiens]                              250   1e-65
gi|22547221 tolloid-like 1 [Homo sapiens]                             151   9e-36
gi|6912724 tolloid-like 2 [Homo sapiens]                              144   8e-34
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom...   138   6e-32
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom...   138   6e-32
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...   138   6e-32
gi|72384339 CUB domain containing protein 2 [Homo sapiens]            136   3e-31
gi|5031863 galectin 3 binding protein [Homo sapiens]                  134   1e-30
gi|126091152 cubilin [Homo sapiens]                                   125   5e-28
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]             121   7e-27
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]       114   1e-24
gi|5803080 macrophage receptor with collagenous structure [Homo ...   112   3e-24
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo...   105   5e-22

>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
            [Homo sapiens]
          Length = 2413

 Score = 5200 bits (13490), Expect = 0.0
 Identities = 2413/2413 (100%), Positives = 2413/2413 (100%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480

Query: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540
            LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA
Sbjct: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540

Query: 541  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL 600
            MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL
Sbjct: 541  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL 600

Query: 601  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660
            ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG
Sbjct: 601  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660

Query: 661  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
            SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL
Sbjct: 661  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720

Query: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
            PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT
Sbjct: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780

Query: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840
            SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT
Sbjct: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840

Query: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900
            PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC
Sbjct: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900

Query: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960
            RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI
Sbjct: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960

Query: 961  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1020
            CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD
Sbjct: 961  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1020

Query: 1021 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1080
            SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
Sbjct: 1021 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1080

Query: 1081 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140
            NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR
Sbjct: 1081 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140

Query: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200
            GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS
Sbjct: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200

Query: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1260
            CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
Sbjct: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1260

Query: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320
            QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
Sbjct: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320

Query: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1380
            SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL
Sbjct: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1380

Query: 1381 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG 1440
            RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
Sbjct: 1381 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG 1440

Query: 1441 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST 1500
            PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST
Sbjct: 1441 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST 1500

Query: 1501 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 1560
            AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG
Sbjct: 1501 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 1560

Query: 1561 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD 1620
            NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD
Sbjct: 1561 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD 1620

Query: 1621 TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 1680
            TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 1621 TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 1680

Query: 1681 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS
Sbjct: 1681 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740

Query: 1741 ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS 1800
            ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS
Sbjct: 1741 ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS 1800

Query: 1801 GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR 1860
            GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR
Sbjct: 1801 GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR 1860

Query: 1861 SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA 1920
            SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA
Sbjct: 1861 SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA 1920

Query: 1921 EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED 1980
            EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED
Sbjct: 1921 EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED 1980

Query: 1981 AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 2040
            AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV
Sbjct: 1981 AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 2040

Query: 2041 QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI 2100
            QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI
Sbjct: 2041 QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI 2100

Query: 2101 SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY 2160
            SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY
Sbjct: 2101 SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY 2160

Query: 2161 ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM 2220
            ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM
Sbjct: 2161 ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM 2220

Query: 2221 LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ 2280
            LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ
Sbjct: 2221 LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ 2280

Query: 2281 DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA 2340
            DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA
Sbjct: 2281 DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA 2340

Query: 2341 RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI 2400
            RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI
Sbjct: 2341 RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI 2400

Query: 2401 QLQTPPRREEEPR 2413
            QLQTPPRREEEPR
Sbjct: 2401 QLQTPPRREEEPR 2413


>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
            [Homo sapiens]
          Length = 2403

 Score = 5170 bits (13411), Expect = 0.0
 Identities = 2403/2413 (99%), Positives = 2403/2413 (99%), Gaps = 10/2413 (0%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS          DTLPTIT
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS----------DTLPTIT 470

Query: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540
            LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA
Sbjct: 471  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 530

Query: 541  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL 600
            MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL
Sbjct: 531  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL 590

Query: 601  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660
            ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG
Sbjct: 591  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 650

Query: 661  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
            SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL
Sbjct: 651  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 710

Query: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
            PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT
Sbjct: 711  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 770

Query: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840
            SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT
Sbjct: 771  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 830

Query: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900
            PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC
Sbjct: 831  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 890

Query: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960
            RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI
Sbjct: 891  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 950

Query: 961  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1020
            CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD
Sbjct: 951  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1010

Query: 1021 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1080
            SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH
Sbjct: 1011 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1070

Query: 1081 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140
            NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR
Sbjct: 1071 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1130

Query: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200
            GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS
Sbjct: 1131 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1190

Query: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1260
            CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
Sbjct: 1191 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1250

Query: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320
            QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC
Sbjct: 1251 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1310

Query: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1380
            SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL
Sbjct: 1311 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1370

Query: 1381 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG 1440
            RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
Sbjct: 1371 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG 1430

Query: 1441 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST 1500
            PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST
Sbjct: 1431 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST 1490

Query: 1501 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 1560
            AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG
Sbjct: 1491 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 1550

Query: 1561 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD 1620
            NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD
Sbjct: 1551 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD 1610

Query: 1621 TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 1680
            TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 1611 TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 1670

Query: 1681 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS
Sbjct: 1671 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1730

Query: 1741 ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS 1800
            ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS
Sbjct: 1731 ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS 1790

Query: 1801 GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR 1860
            GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR
Sbjct: 1791 GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR 1850

Query: 1861 SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA 1920
            SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA
Sbjct: 1851 SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA 1910

Query: 1921 EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED 1980
            EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED
Sbjct: 1911 EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED 1970

Query: 1981 AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 2040
            AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV
Sbjct: 1971 AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 2030

Query: 2041 QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI 2100
            QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI
Sbjct: 2031 QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI 2090

Query: 2101 SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY 2160
            SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY
Sbjct: 2091 SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY 2150

Query: 2161 ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM 2220
            ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM
Sbjct: 2151 ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM 2210

Query: 2221 LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ 2280
            LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ
Sbjct: 2211 LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ 2270

Query: 2281 DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA 2340
            DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA
Sbjct: 2271 DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA 2330

Query: 2341 RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI 2400
            RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI
Sbjct: 2331 RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI 2390

Query: 2401 QLQTPPRREEEPR 2413
            QLQTPPRREEEPR
Sbjct: 2391 QLQTPPRREEEPR 2403


>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
            [Homo sapiens]
          Length = 1785

 Score = 3482 bits (9029), Expect = 0.0
 Identities = 1625/1693 (95%), Positives = 1643/1693 (97%), Gaps = 7/1693 (0%)

Query: 726  GSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 785
            GS+S L LRLVNG  RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWA SAPGN
Sbjct: 95   GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154

Query: 786  ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDT 845
            A FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICS +Q + T  P++
Sbjct: 155  AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214

Query: 846  WP---TSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQ 902
            WP   +    T G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDT+DANVVCRQ
Sbjct: 215  WPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 274

Query: 903  LGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962
            LGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNC HSEDAGVICS
Sbjct: 275  LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334

Query: 963  AAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSW 1022
            A  S  TPSPDT PT    AST G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSW
Sbjct: 335  APQSRPTPSPDTWPTSH--ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 392

Query: 1023 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1082
            DT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNC
Sbjct: 393  DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNC 452

Query: 1083 GHSEDAGVICSASQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140
             HSEDAGVICSA+ S  TPSPDT PT    AST GSESSLALRLVNGGDRCQGRVEVLY+
Sbjct: 453  QHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQ 512

Query: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200
            GSWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS
Sbjct: 513  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 572

Query: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1260
            CPHNGWLSHNCGH EDAGVICSASQS+PTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
Sbjct: 573  CPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 632

Query: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320
            QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRC
Sbjct: 633  QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 692

Query: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1380
            SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL
Sbjct: 693  SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 752

Query: 1381 RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG 1440
            RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG
Sbjct: 753  RLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSG 812

Query: 1441 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST 1500
            PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST
Sbjct: 813  PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAST 872

Query: 1501 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 1560
            AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG
Sbjct: 873  AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 932

Query: 1561 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD 1620
            NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD
Sbjct: 933  NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPD 992

Query: 1621 TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 1680
            TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 993  TWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 1052

Query: 1681 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS
Sbjct: 1053 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1112

Query: 1741 ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS 1800
            ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS
Sbjct: 1113 ATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNS 1172

Query: 1801 GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR 1860
            GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR
Sbjct: 1173 GYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFR 1232

Query: 1861 SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA 1920
            SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA
Sbjct: 1233 SDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA 1292

Query: 1921 EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED 1980
            EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED
Sbjct: 1293 EVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRED 1352

Query: 1981 AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 2040
            AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV
Sbjct: 1353 AGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEV 1412

Query: 2041 QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI 2100
            QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI
Sbjct: 1413 QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFI 1472

Query: 2101 SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY 2160
            SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY
Sbjct: 1473 SDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYY 1532

Query: 2161 ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM 2220
            ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM
Sbjct: 1533 ECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVSCRM 1592

Query: 2221 LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ 2280
            LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ
Sbjct: 1593 LQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQ 1652

Query: 2281 DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA 2340
            DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA
Sbjct: 1653 DLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIA 1712

Query: 2341 RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI 2400
            RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI
Sbjct: 1713 RFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPI 1772

Query: 2401 QLQTPPRREEEPR 2413
            QLQTPPRREEEPR
Sbjct: 1773 QLQTPPRREEEPR 1785



 Score = 2381 bits (6171), Expect = 0.0
 Identities = 1144/1398 (81%), Positives = 1188/1398 (84%), Gaps = 68/1398 (4%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480

Query: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540
            LPASTVGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWA
Sbjct: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA 540

Query: 541  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS------ 594
            M APGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGHSEDAGVICS      
Sbjct: 541  MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRP 600

Query: 595  ---------------GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 639
                           G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVV
Sbjct: 601  TPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVV 660

Query: 640  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGV 699
            CRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHEDAGV
Sbjct: 661  CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV 720

Query: 700  ICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCD 759
            ICSA+QS+ TP PDT    T   ST GSESSL LRLVNG DRCQGRVEVLYRGSWGTVCD
Sbjct: 721  ICSASQSQPTPSPDTWP--TSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 778

Query: 760  DSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 819
            D WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS
Sbjct: 779  DYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLS 838

Query: 820  HNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 879
            HNCGHHEDAGVICS SQS+PTPSPDTWPTS ASTAG ES+LALRLVNGGDRC+GRVEVLY
Sbjct: 839  HNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLY 898

Query: 880  RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLW 939
            +GSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLW
Sbjct: 899  QGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLW 958

Query: 940  SCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGG 999
            SCPHNGWLSHNC H EDAGVICSAA S STP PDT  T  LPA TVGSESSLALRLVNGG
Sbjct: 959  SCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGG 1018

Query: 1000 DRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD 1059
            DRC+GRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD
Sbjct: 1019 DRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD 1078

Query: 1060 VRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESS 1119
            VRCSG+ESYLWSCPH GWL+HNCGH EDAGVICSA+Q   T + D W  +  +TA   S+
Sbjct: 1079 VRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPTTTTTARPSSN 1137

Query: 1120 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQ 1179
                       C G +     G++ +     +  N+A        C W +      R   
Sbjct: 1138 -----------CGGFL-FYASGTFSSPSYPAYYPNNAK-------CVWEIEVNSGYRINL 1178

Query: 1180 GSGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS 1238
            G   + L+    CS     ++    N  L          G IC+ ++   T S +     
Sbjct: 1179 GFSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRMTIH 1230

Query: 1239 HASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYWDTN 1283
              S    +            S   LRLVN       C GRVE+ + G+WGTVCDD W   
Sbjct: 1231 FRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQ 1290

Query: 1284 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 1343
            +A VVCRQLGCG A SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H 
Sbjct: 1291 EAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHR 1350

Query: 1344 EDAGVICSASQSQPTPSP 1361
            EDAGVICS +    TP+P
Sbjct: 1351 EDAGVICSGNHLS-TPAP 1367



 Score = 2115 bits (5480), Expect = 0.0
 Identities = 967/1037 (93%), Positives = 988/1037 (95%), Gaps = 4/1037 (0%)

Query: 592  ICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 651
            +  G +S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWA SA
Sbjct: 92   VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151

Query: 652  PGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPR 711
            PGNA FGQGSGPI LDDVRCSGHESYLWSCP+NGWLSHNCGH EDAGVICSAAQ +ST R
Sbjct: 152  PGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLR 211

Query: 712  PDTLSTITLPP-STVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 770
            P++      PP  T GSESSL LRLVNG DRC+GRVEVLYRGSWGTVCDD WDTNDANVV
Sbjct: 212  PESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVV 271

Query: 771  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV 830
            CRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCPHNGWL+HNCGH EDAGV
Sbjct: 272  CRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGV 331

Query: 831  ICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 890
            ICS  QSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS
Sbjct: 332  ICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 391

Query: 891  WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 950
            WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN
Sbjct: 392  WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 451

Query: 951  CQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLY 1010
            CQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLY
Sbjct: 452  CQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLY 511

Query: 1011 QGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLW 1070
            QGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLW
Sbjct: 512  QGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLW 571

Query: 1071 SCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR 1130
            SCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR
Sbjct: 572  SCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR 631

Query: 1131 CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 1190
            CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR
Sbjct: 632  CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVR 691

Query: 1191 CSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLA 1250
            CSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLA
Sbjct: 692  CSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLA 751

Query: 1251 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGS 1310
            LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGS
Sbjct: 752  LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGS 811

Query: 1311 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHAS 1370
            GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS AS
Sbjct: 812  GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRAS 871

Query: 1371 TAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAP 1430
            TAGSES+LALRLVNGGDRC+GRVEVLY+GSWGTVCDDYWDTNDANVVCRQLGCGWA SAP
Sbjct: 872  TAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP 931

Query: 1431 GNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSP 1490
            GNA+FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA+QSQ TP P
Sbjct: 932  GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRP 991

Query: 1491 DTWPTSR--ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCR 1548
            DTW T+   A T GSES+LALRLVNGGDRCRGRVEVLY+GSWGTVCDD WDTNDANVVCR
Sbjct: 992  DTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCR 1051

Query: 1549 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 1608
            QLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWL+HNCGHHEDAGVIC
Sbjct: 1052 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVIC 1111

Query: 1609 SAAQSQSTPRPDTWLTT 1625
            SA Q  ST   D W  T
Sbjct: 1112 SATQINST-TTDWWHPT 1127



 Score =  602 bits (1552), Expect = e-171
 Identities = 319/535 (59%), Positives = 355/535 (66%), Gaps = 35/535 (6%)

Query: 83   PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
            PS  T  ++ A   GS+S LALRLVNG  RC+GRVE+LY+GSWGTVCDD WDTNDANVVC
Sbjct: 860  PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 919

Query: 141  RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
            RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI
Sbjct: 920  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 979

Query: 201  CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
            CSAAQ QST RP++W +  + P  T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD
Sbjct: 980  CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 1038

Query: 261  DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
            D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT
Sbjct: 1039 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 1098

Query: 321  HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380
            HNCGH EDAGVICSA Q   T + D W  +  +TA P S+           C G    L+
Sbjct: 1099 HNCGHHEDAGVICSATQINSTTT-DWWHPTTTTTARPSSN-----------CGG---FLF 1143

Query: 381  RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGY---ES 437
              S GT    S+     N       C W        R   G   + L+      +   E 
Sbjct: 1144 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1198

Query: 438  YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST---PSPDTLPTITLPASTVGSESSLAL 494
            +  S   +  L   C    D   I +++++  T    S  +       A      S   L
Sbjct: 1199 FDGSLNSSLLLGKICN---DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATL 1255

Query: 495  RLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ 551
            RLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A+ A GNA FG 
Sbjct: 1256 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1315

Query: 552  GSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVN 606
            GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG   S     +N
Sbjct: 1316 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLN 1370


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score = 3425 bits (8882), Expect = 0.0
 Identities = 1605/1696 (94%), Positives = 1630/1696 (96%), Gaps = 10/1696 (0%)

Query: 726  GSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 785
            GS+S L LRLVNG  RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWA SAPGN
Sbjct: 95   GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154

Query: 786  ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDT 845
            A FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICS +Q + T  P++
Sbjct: 155  AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214

Query: 846  WP---TSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQ 902
            WP   +    T G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDT+DANVVCRQ
Sbjct: 215  WPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 274

Query: 903  LGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962
            LGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNC HSEDAGVICS
Sbjct: 275  LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334

Query: 963  AAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSW 1022
            A  S  TPSPDT PT    AST GSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSW
Sbjct: 335  APQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 392

Query: 1023 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1082
            DT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNC
Sbjct: 393  DTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNC 452

Query: 1083 GHSEDAGVICSASQSRPTPSPDTWPTSH--ASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140
             HSEDAGVICSA+ S  TPSPDT PT    AST GSESSLALRLVNGGDRCQGRVEVLYR
Sbjct: 453  QHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYR 512

Query: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200
            GSWGTVCDD WDTNDANVVCRQLGCGWAM APGNARFGQGSGPIVLDDVRCSG+ESYLWS
Sbjct: 513  GSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWS 572

Query: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSHA--STAGSESSLALRLVNGG 1257
            CPHNGWLSHNCGH EDAGVICSA Q  PTP  P +WP+SHA  +  G ESSLALRLVNGG
Sbjct: 573  CPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGG 632

Query: 1258 DRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 1317
            DRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD
Sbjct: 633  DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 692

Query: 1318 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESS 1377
            VRCSGHESYLWSCP+NGWLSHNCGHHEDAGVICSA+QS+ TP PDTWPTSHASTAGSESS
Sbjct: 693  VRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESS 752

Query: 1378 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQ 1437
            LALRLVNGGDRCQGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWA SAPGNARFGQ
Sbjct: 753  LALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ 812

Query: 1438 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSR 1497
            GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICSASQS+PTPSPDTWPTSR
Sbjct: 813  GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSR 872

Query: 1498 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1557
            ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS
Sbjct: 873  ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 932

Query: 1558 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP 1617
            APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP
Sbjct: 933  APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTP 992

Query: 1618 RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV 1677
            RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV
Sbjct: 993  RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVV 1052

Query: 1678 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 1737
            CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV
Sbjct: 1053 CRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV 1112

Query: 1738 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE 1797
            ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE
Sbjct: 1113 ICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIE 1172

Query: 1798 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI 1857
            VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI
Sbjct: 1173 VNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTI 1232

Query: 1858 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1917
            HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI
Sbjct: 1233 HFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1292

Query: 1918 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1977
            QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH
Sbjct: 1293 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1352

Query: 1978 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD 2037
            REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD
Sbjct: 1353 REDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWD 1412

Query: 2038 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI 2097
            IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI
Sbjct: 1413 IEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSI 1472

Query: 2098 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN 2157
            RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN
Sbjct: 1473 RFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWN 1532

Query: 2158 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS 2217
            GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS
Sbjct: 1533 GYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSGGIIKRRTDLRIHVS 1592

Query: 2218 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD 2277
            CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD
Sbjct: 1593 CRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVD 1652

Query: 2278 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL 2337
            LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL
Sbjct: 1653 LNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSL 1712

Query: 2338 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL 2397
            RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL
Sbjct: 1713 RIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVL 1772

Query: 2398 GPIQLQTPPRREEEPR 2413
            GPIQLQTPPRREEEPR
Sbjct: 1773 GPIQLQTPPRREEEPR 1788



 Score = 2390 bits (6195), Expect = 0.0
 Identities = 1151/1401 (82%), Positives = 1190/1401 (84%), Gaps = 71/1401 (5%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTIT 480

Query: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540
            LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA
Sbjct: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540

Query: 541  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS------ 594
            MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS      
Sbjct: 541  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLP 600

Query: 595  ------------------GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 636
                              GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA
Sbjct: 601  TPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDA 660

Query: 637  NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 696
            NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED
Sbjct: 661  NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED 720

Query: 697  AGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 756
            AGVICSAAQSRSTPRPDT    T   ST GSESSL LRLVNG DRCQGRVEVLY+GSWGT
Sbjct: 721  AGVICSAAQSRSTPRPDTWP--TSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGT 778

Query: 757  VCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 816
            VCDDSWDTNDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG
Sbjct: 779  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 838

Query: 817  WLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVE 876
            WLSHNCGH EDAGVICS SQSRPTPSPDTWPTS ASTAG ES+LALRLVNGGDRC+GRVE
Sbjct: 839  WLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVE 898

Query: 877  VLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYES 936
            VLY+GSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSG+ES
Sbjct: 899  VLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHES 958

Query: 937  YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLV 996
            YLWSCPHNGWLSHNC H EDAGVICSAA S STP PDT  T  LPA TVGSESSLALRLV
Sbjct: 959  YLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLV 1018

Query: 997  NGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 1056
            NGGDRC+GRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV
Sbjct: 1019 NGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIV 1078

Query: 1057 LDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGS 1116
            LDDVRCSG+ESYLWSCPH GWL+HNCGH EDAGVICSA+Q   T + D W  +  +TA  
Sbjct: 1079 LDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST-TTDWWHPTTTTTARP 1137

Query: 1117 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAR 1176
             S+           C G +     G++ +     +  N+A        C W +      R
Sbjct: 1138 SSN-----------CGGFL-FYASGTFSSPSYPAYYPNNAK-------CVWEIEVNSGYR 1178

Query: 1177 FGQGSGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTW 1235
               G   + L+    CS     ++    N  L          G IC+ ++   T S +  
Sbjct: 1179 INLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRM 1230

Query: 1236 PTSHASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYW 1280
                 S    +            S   LRLVN       C GRVE+ + G+WGTVCDD W
Sbjct: 1231 TIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSW 1290

Query: 1281 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1340
               +A VVCRQLGCG A SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC
Sbjct: 1291 TIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNC 1350

Query: 1341 GHHEDAGVICSASQSQPTPSP 1361
             H EDAGVICS +    TP+P
Sbjct: 1351 NHREDAGVICSGNHLS-TPAP 1370



 Score =  602 bits (1552), Expect = e-171
 Identities = 319/535 (59%), Positives = 355/535 (66%), Gaps = 35/535 (6%)

Query: 83   PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
            PS  T  ++ A   GS+S LALRLVNG  RC+GRVE+LY+GSWGTVCDD WDTNDANVVC
Sbjct: 863  PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 922

Query: 141  RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
            RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI
Sbjct: 923  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 982

Query: 201  CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
            CSAAQ QST RP++W +  + P  T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD
Sbjct: 983  CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 1041

Query: 261  DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
            D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT
Sbjct: 1042 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 1101

Query: 321  HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380
            HNCGH EDAGVICSA Q   T + D W  +  +TA P S+           C G    L+
Sbjct: 1102 HNCGHHEDAGVICSATQINSTTT-DWWHPTTTTTARPSSN-----------CGG---FLF 1146

Query: 381  RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGY---ES 437
              S GT    S+     N       C W        R   G   + L+      +   E 
Sbjct: 1147 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1201

Query: 438  YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST---PSPDTLPTITLPASTVGSESSLAL 494
            +  S   +  L   C    D   I +++++  T    S  +       A      S   L
Sbjct: 1202 FDGSLNSSLLLGKICN---DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATL 1258

Query: 495  RLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ 551
            RLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A+ A GNA FG 
Sbjct: 1259 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1318

Query: 552  GSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVN 606
            GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG   S     +N
Sbjct: 1319 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLN 1373


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score = 3200 bits (8297), Expect = 0.0
 Identities = 1503/1590 (94%), Positives = 1527/1590 (96%), Gaps = 11/1590 (0%)

Query: 833  SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWD 892
            +V++    PS  T  ++ A   G +S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWD
Sbjct: 75   TVAEGSLIPSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWD 132

Query: 893  TSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQ 952
            T+DANVVCRQLGCGWA SAPGNA FGQGSGPI LDDVRCSG+ESYLWSCPHNGWLSHNC 
Sbjct: 133  TNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCG 192

Query: 953  HSEDAGVICSAAHSWSTPSPDTLPT-ITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQ 1011
            H EDAGVICSAA   ST  P++ P  I+ P  T GSESSLALRLVNGGDRC+GRVEVLY+
Sbjct: 193  HGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYR 252

Query: 1012 GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1071
            GSWGTVCDD WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSGHESYLWS
Sbjct: 253  GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 312

Query: 1072 CPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1131
            CPHNGWL+HNCGHSEDAGVICSA QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC
Sbjct: 313  CPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 372

Query: 1132 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 1191
            QGRVEVLYRGSWGTVCDD WDT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRC
Sbjct: 373  QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432

Query: 1192 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSP------DTWPTSH--ASTA 1243
            SG+ESYLWSCPHNGWLSHNC H EDAGVICSA+ S  TPSP      DT PT    AST 
Sbjct: 433  SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTV 492

Query: 1244 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 1303
            GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWA  APGN
Sbjct: 493  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 552

Query: 1304 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1363
            ARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICSA+QS+ TP PDT
Sbjct: 553  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDT 612

Query: 1364 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1423
            WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDD WDTNDANVVCRQLGC
Sbjct: 613  WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 672

Query: 1424 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1483
            GWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVICSASQ
Sbjct: 673  GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQ 732

Query: 1484 SQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA 1543
            S+PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA
Sbjct: 733  SRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA 792

Query: 1544 NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1603
            NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED
Sbjct: 793  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 852

Query: 1604 AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 1663
            AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT
Sbjct: 853  AGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGT 912

Query: 1664 VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG 1723
            VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG
Sbjct: 913  VCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKG 972

Query: 1724 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1783
            WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP
Sbjct: 973  WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1032

Query: 1784 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND 1843
            AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND
Sbjct: 1033 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND 1092

Query: 1844 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH 1903
            TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH
Sbjct: 1093 TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYH 1152

Query: 1904 GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW 1963
            GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW
Sbjct: 1153 GGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLW 1212

Query: 1964 QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF 2023
            QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF
Sbjct: 1213 QCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPF 1272

Query: 2024 YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG 2083
            YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG
Sbjct: 1273 YPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDG 1332

Query: 2084 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS 2143
            ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS
Sbjct: 1333 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQS 1392

Query: 2144 LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG 2203
            LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG
Sbjct: 1393 LGFSASDLVISTWNGYYECRPQITPNLVIFTIPYSGCGTFKQADNDTIDYSNFLTAAVSG 1452

Query: 2204 GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS 2263
            GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS
Sbjct: 1453 GIIKRRTDLRIHVSCRMLQNTWVDTMYIANDTIHVANNTIQVEEVQYGNFDVNISFYTSS 1512

Query: 2264 SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC 2323
            SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC
Sbjct: 1513 SFLYPVTSRPYYVDLNQDLYVQAEILHSDAVLTLFVDTCVASPYSNDFTSLTYDLIRSGC 1572

Query: 2324 VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK 2383
            VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK
Sbjct: 1573 VRDDTYGPYSSPSLRIARFRFRAFHFLNRFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSK 1632

Query: 2384 RDVGSYQEKVDVVLGPIQLQTPPRREEEPR 2413
            RDVGSYQEKVDVVLGPIQLQTPPRREEEPR
Sbjct: 1633 RDVGSYQEKVDVVLGPIQLQTPPRREEEPR 1662



 Score = 2092 bits (5419), Expect = 0.0
 Identities = 1019/1277 (79%), Positives = 1054/1277 (82%), Gaps = 78/1277 (6%)

Query: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDPTVAEGSPFPSESTLESTV 60
            MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLD TVAEGSPFPSE TLESTV
Sbjct: 1    MGISTVILEMCLLWGQVLSTGGWIPRTTDYASLIPSEVPLDTTVAEGSPFPSELTLESTV 60

Query: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120
            AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR
Sbjct: 61   AEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYR 120

Query: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180
            GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS
Sbjct: 121  GSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWS 180

Query: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240
            CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG
Sbjct: 181  CPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGG 240

Query: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
            DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD
Sbjct: 241  DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300

Query: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
            VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAG ESS
Sbjct: 301  VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGSESS 360

Query: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420
            LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ
Sbjct: 361  LALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQ 420

Query: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP------D 474
            GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSP      D
Sbjct: 421  GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTD 480

Query: 475  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 534
            TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ
Sbjct: 481  TLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQ 540

Query: 535  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
            LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS
Sbjct: 541  LGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 600

Query: 595  ---------------------GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 633
                                 G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDT
Sbjct: 601  AAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDT 660

Query: 634  NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGH 693
            NDANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGH
Sbjct: 661  NDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 720

Query: 694  HEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGS 753
             EDAGVICSA+QSR TP PDT  T     ST GSES+L LRLVNG DRC+GRVEVLY+GS
Sbjct: 721  SEDAGVICSASQSRPTPSPDTWPTSR--ASTAGSESTLALRLVNGGDRCRGRVEVLYQGS 778

Query: 754  WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP 813
            WGTVCDD WDTNDANVVCRQLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP
Sbjct: 779  WGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCP 838

Query: 814  HNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSH--ASTAGPESSLALRLVNGGDRC 871
            HNGWLSHNCGHHEDAGVICS +QS+ TP PDTW T++  A T G ESSLALRLVNGGDRC
Sbjct: 839  HNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRC 898

Query: 872  QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 931
            +GRVEVLYRGSWGTVCDDSWDT+DANVVCRQLGCGWA SAPGNARFGQGSGPIVLDDVRC
Sbjct: 899  RGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 958

Query: 932  SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 991
            SG ESYLWSCPH GWL+HNC H EDAGVICSA    ST +    PT T  A         
Sbjct: 959  SGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTA--------- 1009

Query: 992  ALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1051
                      C G    L+  S GT    S+     N       C W +      R   G
Sbjct: 1010 -----RPSSNCGG---FLFYAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLG 1056

Query: 1052 SGPIVLD-DVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSH 1110
               + L+    CS     ++    N  L          G IC+ ++   T S +      
Sbjct: 1057 FSNLKLEAHHNCSFDYVEIFDGSLNSSLL--------LGKICNDTRQIFTSSYNRMTIHF 1108

Query: 1111 ASTAGSE------------SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDYWDTND 1155
             S    +            S   LRLVN       C GRVE+ + G+WGTVCDD W   +
Sbjct: 1109 RSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQE 1168

Query: 1156 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1215
            A VVCRQLGCG A+SA GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H E
Sbjct: 1169 AEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHRE 1228

Query: 1216 DAGVICSASQSQPTPSP 1232
            DAGVICS +    TP+P
Sbjct: 1229 DAGVICSGNHLS-TPAP 1244



 Score =  602 bits (1552), Expect = e-171
 Identities = 319/535 (59%), Positives = 355/535 (66%), Gaps = 35/535 (6%)

Query: 83   PSESTLESTVAE--GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
            PS  T  ++ A   GS+S LALRLVNG  RC+GRVE+LY+GSWGTVCDD WDTNDANVVC
Sbjct: 737  PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 796

Query: 141  RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
            RQLGCGWAMSAPGNA FGQGSGPI LDDVRCSGHESYLWSCPHNGWLSHNCGH EDAGVI
Sbjct: 797  RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 856

Query: 201  CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
            CSAAQ QST RP++W +  + P  T GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD
Sbjct: 857  CSAAQSQSTPRPDTW-LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 915

Query: 261  DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
            D WDTNDANVVCRQLGCGWAMSAPGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPH GWLT
Sbjct: 916  DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLT 975

Query: 321  HNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLY 380
            HNCGH EDAGVICSA Q   T + D W  +  +TA P S+           C G    L+
Sbjct: 976  HNCGHHEDAGVICSATQINSTTT-DWWHPTTTTTARPSSN-----------CGG---FLF 1020

Query: 381  RGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGY---ES 437
              S GT    S+     N       C W        R   G   + L+      +   E 
Sbjct: 1021 YAS-GTFSSPSYPAYYPN----NAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEI 1075

Query: 438  YLWSCPHNGWLSHNCQHSEDAGVICSAAHSWST---PSPDTLPTITLPASTVGSESSLAL 494
            +  S   +  L   C    D   I +++++  T    S  +       A      S   L
Sbjct: 1076 FDGSLNSSLLLGKICN---DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATL 1132

Query: 495  RLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ 551
            RLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A+ A GNA FG 
Sbjct: 1133 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1192

Query: 552  GSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVN 606
            GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG   S     +N
Sbjct: 1193 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLN 1247


>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
            sapiens]
          Length = 1453

 Score = 1101 bits (2848), Expect = 0.0
 Identities = 610/1532 (39%), Positives = 783/1532 (51%), Gaps = 224/1532 (14%)

Query: 230  SSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF 289
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     Q 
Sbjct: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQA 103

Query: 290  GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPT 349
                G I LDDV C G+ES LW C H  W +HNC H ED GV C                
Sbjct: 104  VTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG-------------- 149

Query: 350  SHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA 409
                    E++L LRLV+G + C GRVEV ++  WGT+CDD W+ + A VVCRQLGC  +
Sbjct: 150  --------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSS 201

Query: 410  TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWS 469
              + G         PI LDD+ C G E  LW+C H GW +H+C H+ED  + C       
Sbjct: 202  FISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY------ 255

Query: 470  TPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 529
                                S L LRLV G +RC GRVE+  +G WGTVC   W+   A+
Sbjct: 256  ------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAAD 297

Query: 530  VVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDA 589
            VVC+QLGCG A+   G      GS  + LD V CSGNES+LW C H+G ++ +C H  D 
Sbjct: 298  VVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDV 357

Query: 590  GVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 649
             VICS   + L LRL +G + C GRVEV     W T+CD +W    A VVC+QLGC ++ 
Sbjct: 358  SVICS-DGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSV 416

Query: 650  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRST 709
                 A+    +  I ++ + C+G+ES LW C  +G     C    DAGVICS       
Sbjct: 417  FGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICS------- 469

Query: 710  PRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANV 769
                              ++ L LRLV     C GR+EV Y+G WGTVC D W T +A V
Sbjct: 470  -----------------DKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAV 512

Query: 770  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAG 829
            VC+QLGCG      G   F + SGPI LDDV C G+ES +W C H+GW  HNC H ED  
Sbjct: 513  VCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVI 572

Query: 830  VICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 889
            V CS           TW               LRLV G +RC GR+EV ++G WGTVCDD
Sbjct: 573  VTCS--------GDATW--------------GLRLVGGSNRCSGRLEVYFQGRWGTVCDD 610

Query: 890  SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSH 949
             W++  A VVC QL C  +    G      G G I LDDV C G ES LWSC ++GW ++
Sbjct: 611  GWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNN 670

Query: 950  NCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVL 1009
            +C HSED GVICS A                        S + LRLV G  RC G+VEV 
Sbjct: 671  DCSHSEDVGVICSDA------------------------SDMELRLVGGSSRCAGKVEVN 706

Query: 1010 YQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYL 1069
             QG+ G +C + W  N A VVCRQL CG A+       F + +  I++ +  C+G E+ L
Sbjct: 707  VQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASL 766

Query: 1070 WSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGD 1129
            W C    W    C  + +A +ICSA +                          RLV    
Sbjct: 767  WDCIRWEWKQTACHLNMEASLICSAHRQP------------------------RLVGADM 802

Query: 1130 RCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDV 1189
             C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+S      FG+G+G    +  
Sbjct: 803  PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKF 862

Query: 1190 RCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1249
            +C G E++L  CP        C H  + GV+CS                           
Sbjct: 863  QCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD----------------------- 899

Query: 1250 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1309
             +RLVNG  +C G+VE+   G WG++CD +WD  DA V+CRQL CG A S  G    G+ 
Sbjct: 900  -VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGER 958

Query: 1310 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT-PSPDTWPTSH 1368
            S  +      C G+ES L +C      +  C H     VIC+ S +QP  P        +
Sbjct: 959  SVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPY 1018

Query: 1369 ASTAGSESSL------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 1422
             S     S+L       LRLV+G  RC GRVE+ + G WGT+CDD WD +DA+VVC++LG
Sbjct: 1019 LSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLG 1078

Query: 1423 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1482
            CG A +A  +A FG+GSGPI LDD+ C+G ES+LW CP  GW  H+C H EDAGVICS  
Sbjct: 1079 CGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICS-- 1136

Query: 1483 QSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTND 1542
                                  + L L      + C GR+EV Y G+WG+V      T  
Sbjct: 1137 --------------------EFTALRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAI 1176

Query: 1543 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1602
            A +VCRQLGCG             GSG + +DD++C      +W C    W         
Sbjct: 1177 AGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPW--------- 1227

Query: 1603 DAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGD-RCRGRVEVLYRGSW 1661
                     +  S+P  +TW+T          E  + +R   GGD  C GRVE+ + GSW
Sbjct: 1228 --------ERRISSPAEETWIT---------CEDRIRVR---GGDTECSGRVEIWHAGSW 1267

Query: 1662 GTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPH 1721
            GTVCDDSWD  +A VVC+QLGCG A++A  +A FGQG+G I LDD+RC GNES+LW C  
Sbjct: 1268 GTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDCHA 1327

Query: 1722 KGWLTHNCGHHEDAGVICSATQINSTTTDWWH 1753
            K W   +CGH EDAGV CS   + S      H
Sbjct: 1328 KPWGQSDCGHKEDAGVRCSGQSLKSLNASSGH 1359



 Score = 1098 bits (2841), Expect = 0.0
 Identities = 603/1534 (39%), Positives = 786/1534 (51%), Gaps = 229/1534 (14%)

Query: 92   VAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 151
            ++  + + L LRLVNGDG C G VE+ ++G WGTVCDD W+T  + VVC+QLGC ++ + 
Sbjct: 38   ISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM 97

Query: 152  PGNAWFGQG---SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQS 208
                 FGQ     G I LDDV C G+ES LW C H  W SHNC HGED GV C       
Sbjct: 98   ---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----- 149

Query: 209  TLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDA 268
                                E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A
Sbjct: 150  --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189

Query: 269  NVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSED 328
             VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW  H+C H+ED
Sbjct: 190  AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249

Query: 329  AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
              + C                         S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 250  VTLTCY----------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVC 287

Query: 389  DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
               W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 288  HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347

Query: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508
            + +C H  D  VICS                          + L LRL +G + C GRVE
Sbjct: 348  NFDCLHQNDVSVICS------------------------DGADLELRLADGSNNCSGRVE 383

Query: 509  VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNES 568
            V     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + C+GNES
Sbjct: 384  VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNES 443

Query: 569  YLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 628
             LW C ++G     C    DAGVICS  ++ L LRLV     C GR+EV Y+G WGTVC 
Sbjct: 444  ALWDCTYDGKAKRTCFRRSDAGVICS-DKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCH 502

Query: 629  DSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLS 688
            D W T +A VVC+QLGCG      G   F + SGPI LDDV C G+ES +W C ++GW  
Sbjct: 503  DRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGK 562

Query: 689  HNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEV 748
            HNC H ED  V CS                         +++  LRLV GS+RC GR+EV
Sbjct: 563  HNCVHREDVIVTCS------------------------GDATWGLRLVGGSNRCSGRLEV 598

Query: 749  LYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESY 808
             ++G WGTVCDD W++  A VVC QL C  +    G      G G I LDDV C G ES 
Sbjct: 599  YFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESD 658

Query: 809  LWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 868
            LWSC ++GW +++C H ED GVICS                        S + LRLV G 
Sbjct: 659  LWSCRNSGWGNNDCSHSEDVGVICS----------------------DASDMELRLVGGS 696

Query: 869  DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 928
             RC G+VEV  +G+ G +C + W  + A VVCRQL CG A        F + +  I++ +
Sbjct: 697  SRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSN 756

Query: 929  VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSE 988
              C+G E+ LW C    W    C  + +A +ICSA                         
Sbjct: 757  SGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQ---------------------- 794

Query: 989  SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 1048
                 RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG A+S      F
Sbjct: 795  ----PRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHF 850

Query: 1049 GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPT 1108
            G+G+G    +  +C G E++L  CP        C HS + GV+CS               
Sbjct: 851  GKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTD----------- 899

Query: 1109 SHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 1168
                         +RLVNG  +C G+VE+   G WG++CD +WD  DA V+CRQL CG A
Sbjct: 900  -------------VRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTA 946

Query: 1169 MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQP 1228
            +S  G    G+ S  +      C G+ES L +C      +  C H     VIC+ S +QP
Sbjct: 947  LSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQP 1006

Query: 1229 T-PSPDTWPTSHASTAGSESSL------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD 1281
              P        + S     S+L       LRLV+G  RC GRVE+ + G WGT+CDD WD
Sbjct: 1007 LFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWD 1066

Query: 1282 TNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCG 1341
             +DA+VVC++LGCG A +A  +A FG+GSGPI LDD+ C+G ES+LW CP  GW  H+C 
Sbjct: 1067 LSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCR 1126

Query: 1342 HHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSW 1401
            H EDAGVICS                        ++L L      + C GR+EV Y G+W
Sbjct: 1127 HKEDAGVICS----------------------EFTALRLYSETETESCAGRLEVFYNGTW 1164

Query: 1402 GTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPH 1461
            G+V      T  A +VCRQLGCG             GSG + +DD++C      +W C  
Sbjct: 1165 GSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLS 1224

Query: 1462 NGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGR 1521
              W                  +   +P+ +TW T             +R+  G   C GR
Sbjct: 1225 APW-----------------ERRISSPAEETWITCED---------RIRVRGGDTECSGR 1258

Query: 1522 VEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGH 1581
            VE+ + GSWGTVCDD WD  +A VVC+QLGCG A++A  +A FGQG+G I LDD+RC G+
Sbjct: 1259 VEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGN 1318

Query: 1582 ESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQS 1615
            ES+LW C    W   +CGH EDAGV CS    +S
Sbjct: 1319 ESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352



 Score =  847 bits (2188), Expect = 0.0
 Identities = 484/1273 (38%), Positives = 640/1273 (50%), Gaps = 195/1273 (15%)

Query: 729  SSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARF 788
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     RF
Sbjct: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100

Query: 789  GQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDT 845
            GQ     G I LDDV C G+ES LW C H  W SHNC H ED GV C             
Sbjct: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCY------------ 148

Query: 846  WPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGC 905
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ + A VVCRQLGC
Sbjct: 149  ----------GEANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC 198

Query: 906  GWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAH 965
              +  + G         PI LDD+ C G E  LW+C H GW +H+C H+ED  + C    
Sbjct: 199  PSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCY--- 255

Query: 966  SWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 1025
                                   S L LRLV G +RC GRVE+  QG WGTVC   W+  
Sbjct: 256  ---------------------DSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNA 294

Query: 1026 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHS 1085
             A+VVC+QLGCG A+   G      GS  + LD V CSG+ES+LW C H+G ++ +C H 
Sbjct: 295  AADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQ 354

Query: 1086 EDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 1145
             D  VICS                        + L LRL +G + C GRVEV     W T
Sbjct: 355  NDVSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWWT 392

Query: 1146 VCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNG 1205
            +CD  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++G
Sbjct: 393  ICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDG 452

Query: 1206 WLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVE 1265
                 C    DAGVICS                       ++ L LRLV     C GR+E
Sbjct: 453  KAKRTCFRRSDAGVICS----------------------DKADLDLRLVGAHSPCYGRLE 490

Query: 1266 VLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHES 1325
            V Y+G WGTVC D W T +A VVC+QLGCG      G   F + SGPI LDDV C G+ES
Sbjct: 491  VKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNES 550

Query: 1326 YLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNG 1385
             +W C H+GW  HNC H ED  V CS           TW               LRLV G
Sbjct: 551  NIWDCEHSGWGKHNCVHREDVIVTCSGDA--------TW--------------GLRLVGG 588

Query: 1386 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLD 1445
             +RC GR+EV ++G WGTVCDD W++  A VVC QL C  +    G      G G I LD
Sbjct: 589  SNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLD 648

Query: 1446 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSES 1505
            DV C G ES LWSC ++GW +++C H ED GVICS +                      S
Sbjct: 649  DVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA----------------------S 686

Query: 1506 TLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFG 1565
             + LRLV G  RC G+VEV  QG+ G +C + W  N A VVCRQL CG A+       F 
Sbjct: 687  DMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFT 746

Query: 1566 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTT 1625
            + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA +             
Sbjct: 747  ERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHRQP----------- 795

Query: 1626 NLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGW 1685
                           RLV     C GRVEV +  +W +VCD  +  + ANV+CR+L CG 
Sbjct: 796  ---------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD 840

Query: 1686 AMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQIN 1745
            A+S      FG+G+G    +  +C G+E++L  CP        C H  + GV+CS     
Sbjct: 841  AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRY--- 897

Query: 1746 STTTDWWHPTTTTTARPSSNCGGFL-FYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1804
                     T        S C G +     G + S     + P +A+ +   +++ G  +
Sbjct: 898  ---------TDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCR-QLSCGTAL 947

Query: 1805 N------LGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC---NDTRQIFTSSYNRM 1855
            +      +G  ++++  H         + D +   ++L    C   N    I T S  + 
Sbjct: 948  STTGGKYIGERSVRVWGHRFHCLGNESLLD-NCQMTVLGAPPCIHGNTVSVICTGSLTQP 1006

Query: 1856 TIHFRSDISFQNTGFLAWYNSFP--SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDD 1913
                 +++S      +   ++     D  LRLV+ +S    CAGRVEIYH G WGT+CDD
Sbjct: 1007 LFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR---CAGRVEIYHDGFWGTICDD 1063

Query: 1914 SWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH 1973
             W + +A VVC++LGCG A +A  +A+FG GSGPI LDD+ C+G ES LWQC +RGW  H
Sbjct: 1064 GWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQH 1123

Query: 1974 NCNHREDAGVICS 1986
            +C H+EDAGVICS
Sbjct: 1124 DCRHKEDAGVICS 1136



 Score =  791 bits (2043), Expect = 0.0
 Identities = 445/1155 (38%), Positives = 575/1155 (49%), Gaps = 192/1155 (16%)

Query: 591  VICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 650
            +I S   + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +
Sbjct: 37   LISSFNGTDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFA 96

Query: 651  APGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSR 707
                 RFGQ     G I LDDV C G+ES LW C +  W SHNC H ED GV C      
Sbjct: 97   M---FRFGQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG---- 149

Query: 708  STPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDA 767
                                E++L LRLV+G++ C GRVEV ++  WGT+CDD W+ N A
Sbjct: 150  --------------------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTA 189

Query: 768  NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 827
             VVCRQLGC  +  + G         PI LDD+ C G+E  LW+C H GW +H+C H+ED
Sbjct: 190  AVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNED 249

Query: 828  AGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 887
              + C  S                      S L LRLV G +RC GRVE+  +G WGTVC
Sbjct: 250  VTLTCYDS----------------------SDLELRLVGGTNRCMGRVELKIQGRWGTVC 287

Query: 888  DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 947
               W+ + A+VVC+QLGCG A    G      GS  + LD V CSG ES+LW C H+G +
Sbjct: 288  HHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTV 347

Query: 948  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 1007
            + +C H  D  VICS                          + L LRL +G + C GRVE
Sbjct: 348  NFDCLHQNDVSVICSDG------------------------ADLELRLADGSNNCSGRVE 383

Query: 1008 VLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHES 1067
            V     W T+CD +W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES
Sbjct: 384  VRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNES 443

Query: 1068 YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 1127
             LW C ++G     C    DAGVICS                       ++ L LRLV  
Sbjct: 444  ALWDCTYDGKAKRTCFRRSDAGVICS----------------------DKADLDLRLVGA 481

Query: 1128 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1187
               C GR+EV Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LD
Sbjct: 482  HSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLD 541

Query: 1188 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES 1247
            DV C G+ES +W C H+GW  HNC H ED  V CS           TW            
Sbjct: 542  DVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDA--------TW------------ 581

Query: 1248 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFG 1307
               LRLV G +RC GR+EV ++G WGTVCDD W++  A VVC QL C  +    G     
Sbjct: 582  --GLRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNAS 639

Query: 1308 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTS 1367
             G G I LDDV C G ES LWSC ++GW +++C H ED GVICS +              
Sbjct: 640  TGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICSDA-------------- 685

Query: 1368 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAT 1427
                    S + LRLV G  RC G+VEV  +G+ G +C + W  N A VVCRQL CG A 
Sbjct: 686  --------SDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAI 737

Query: 1428 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1487
                   F + +  I++ +  C+G E+ LW C    W    C  + +A +ICSA + QP 
Sbjct: 738  RVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHLNMEASLICSAHR-QP- 795

Query: 1488 PSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVC 1547
                                  RLV     C GRVEV +  +W +VCD  +  + ANV+C
Sbjct: 796  ----------------------RLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLC 833

Query: 1548 RQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 1607
            R+L CG A+S      FG+G+G    +  +C G E++L  CP        C H  + GV+
Sbjct: 834  RELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVV 893

Query: 1608 CSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDD 1667
            CS                              +RLVNG  +C G+VE+   G WG++CD 
Sbjct: 894  CSRYTD--------------------------VRLVNGKSQCDGQVEINVLGHWGSLCDT 927

Query: 1668 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTH 1727
             WD  DA V+CRQL CG A+S  G    G+ S  +      C GNES L +C        
Sbjct: 928  HWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAP 987

Query: 1728 NCGHHEDAGVICSAT 1742
             C H     VIC+ +
Sbjct: 988  PCIHGNTVSVICTGS 1002



 Score =  545 bits (1403), Expect = e-154
 Identities = 324/875 (37%), Positives = 421/875 (48%), Gaps = 130/875 (14%)

Query: 1118 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARF 1177
            + L LRLVNG   C G VEV ++G WGTVCDD W+T  + VVC+QLGC ++ +     RF
Sbjct: 44   TDLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAM---FRF 100

Query: 1178 GQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1234
            GQ     G I LDDV C G+ES LW C H  W SHNC H ED GV C             
Sbjct: 101  GQAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYG----------- 149

Query: 1235 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1294
                       E++L LRLV+G + C GRVEV ++  WGT+CDD W+ N A VVCRQLGC
Sbjct: 150  -----------EANLGLRLVDGNNSCSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGC 198

Query: 1295 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1354
              +  + G         PI LDD+ C G+E  LW+C H GW +H+C H+ED  + C  S 
Sbjct: 199  PSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS- 257

Query: 1355 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1414
                                 S L LRLV G +RC GRVE+  +G WGTVC   W+   A
Sbjct: 258  ---------------------SDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAA 296

Query: 1415 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1474
            +VVC+QLGCG A    G      GS  + LD V CSG+ES+LW C H+G ++ +C H  D
Sbjct: 297  DVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQND 356

Query: 1475 AGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVC 1534
              VICS                        + L LRL +G + C GRVEV     W T+C
Sbjct: 357  VSVICSDG----------------------ADLELRLADGSNNCSGRVEVRIHEQWWTIC 394

Query: 1535 DDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1594
            D  W    A VVC+QLGC +++     A+    +  I ++ + C+G+ES LW C ++G  
Sbjct: 395  DQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCTGNESALWDCTYDGKA 454

Query: 1595 SHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVE 1654
               C    DAGVICS                         ++ L LRLV     C GR+E
Sbjct: 455  KRTCFRRSDAGVICS------------------------DKADLDLRLVGAHSPCYGRLE 490

Query: 1655 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNES 1714
            V Y+G WGTVC D W T +A VVC+QLGCG  M   G   F + SGPI LDDV C GNES
Sbjct: 491  VKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNES 550

Query: 1715 YLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFL-FYA 1773
             +W C H GW  HNC H ED  V C      S    W           S+ C G L  Y 
Sbjct: 551  NIWDCEHSGWGKHNCVHREDVIVTC------SGDATWG----LRLVGGSNRCSGRLEVYF 600

Query: 1774 SGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNS 1833
             G + +     +    A  V          I +G  N       +  +  + + D S + 
Sbjct: 601  QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA------STGYGKIWLDDVSCDG 654

Query: 1834 SLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYG 1893
                    +D      S +         D+     G +    S  SD  LRLV  +S   
Sbjct: 655  DE------SDLWSCRNSGWGNNDCSHSEDV-----GVIC---SDASDMELRLVGGSSR-- 698

Query: 1894 LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDV 1953
             CAG+VE+   G  G +C + W +  AEVVCRQL CG A+      +F   +  I + + 
Sbjct: 699  -CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNS 757

Query: 1954 ECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1988
             C+G E++LW C    W    C+   +A +ICS +
Sbjct: 758  GCTGGEASLWDCIRWEWKQTACHLNMEASLICSAH 792



 Score =  172 bits (436), Expect = 4e-42
 Identities = 109/292 (37%), Positives = 142/292 (48%), Gaps = 41/292 (14%)

Query: 54   STLESTVAEGS-PISLESTLESTVAEGSL--IPSESTLESTVAEGSDSGL------ALRL 104
            +T+ +   EGS PI L+  L  T  E  L   PS    +       D+G+      ALRL
Sbjct: 1085 ATVSAHFGEGSGPIWLDD-LNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRL 1143

Query: 105  VNGDGR--CQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSG 162
             +      C GR+E+ Y G+WG+V   +  T  A +VCRQLGCG             GSG
Sbjct: 1144 YSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSG 1203

Query: 163  PIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPP 222
             + +DD++C      +W C                                 W  RIS P
Sbjct: 1204 FMWVDDIQCPKTHISIWQC-----------------------------LSAPWERRISSP 1234

Query: 223  VPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 282
                       +R+  G   C GRVE+ + GSWGTVCDD WD  +A VVC+QLGCG A++
Sbjct: 1235 AEETWITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALA 1294

Query: 283  APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
            A  +A FGQG+G I LDD+RC G+ES+LW C    W   +CGH EDAGV CS
Sbjct: 1295 ALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346



 Score =  138 bits (348), Expect = 6e-32
 Identities = 59/98 (60%), Positives = 73/98 (74%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
            C+GRVEI+H G+WGTVCDDSW + EAEVVC+QLGCG A++AL +A FG G+G I LDD+ 
Sbjct: 1255 CSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMR 1314

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1992
            C G ES LW C  + W   +C H+EDAGV CSG  L +
Sbjct: 1315 CKGNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKS 1352



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 46/121 (38%), Positives = 61/121 (50%), Gaps = 4/121 (3%)

Query: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1942
            +RLVN  S    C G+VEI   G WG++CD  W  ++A V+CRQL CG A+S  G  Y G
Sbjct: 900  VRLVNGKSQ---CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956

Query: 1943 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL-NITR 2001
              S  +      C G ES L  C+     +  C H     VIC+G+      P L N++ 
Sbjct: 957  ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSD 1016

Query: 2002 P 2002
            P
Sbjct: 1017 P 1017



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 33/91 (36%), Positives = 51/91 (56%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
            CAGR+E+++ GTWG+V   + T   A +VCRQLGCG            +GSG + +DD++
Sbjct: 1152 CAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQ 1211

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
            C  T  ++WQC +  W     +  E+  + C
Sbjct: 1212 CPKTHISIWQCLSAPWERRISSPAEETWITC 1242


>gi|44889963 CD163 antigen isoform b [Homo sapiens]
          Length = 1121

 Score =  901 bits (2328), Expect = 0.0
 Identities = 491/1169 (42%), Positives = 633/1169 (54%), Gaps = 171/1169 (14%)

Query: 472  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 526
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W   
Sbjct: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83

Query: 527  DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGH 585
              +V+C QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H
Sbjct: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143

Query: 586  SEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 645
             +DAGV CS   S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL C
Sbjct: 144  QQDAGVTCSDG-SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLEC 202

Query: 646  GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQ 705
            G A S  G++ FG+GSGPI  DD+ C+G+ES LW+C + GW  HNC H EDAGVICS   
Sbjct: 203  GSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG- 261

Query: 706  SRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTN 765
                                   + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ 
Sbjct: 262  -----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298

Query: 766  DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 825
            DA V C+QLGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+
Sbjct: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358

Query: 826  EDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGT 885
            EDAGV CS                        S L LRL  GG RC G VEV  +   G 
Sbjct: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396

Query: 886  VCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPH 943
            VCD  W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +
Sbjct: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKN 454

Query: 944  NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ 1003
              W    C H E+A + CSA                              RLV G   C 
Sbjct: 455  WQWGGLTCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCS 488

Query: 1004 GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1063
            GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C 
Sbjct: 489  GRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCE 548

Query: 1064 GHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALR 1123
            GHES+L  CP        C HS D GV+CS                            +R
Sbjct: 549  GHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IR 584

Query: 1124 LVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 1183
            LVNG   C+GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG ARFG+G+G 
Sbjct: 585  LVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQ 644

Query: 1184 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHA 1240
            I      C+G E ++  CP     +  C   + A VICS +QSQ   S ++    PT   
Sbjct: 645  IWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR-- 702

Query: 1241 STAGSESSLA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1294
             T   ES++A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGC
Sbjct: 703  PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762

Query: 1295 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1354
            G A +A G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   
Sbjct: 763  GEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFM 822

Query: 1355 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDYWDTN 1412
            S                        LRL +   R  C GR+EV Y G+WGTV        
Sbjct: 823  S------------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSET 858

Query: 1413 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 1472
               VVCRQLGC         +     S P+ +D+V+C      LW CP + W        
Sbjct: 859  TVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-------- 910

Query: 1473 EDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGT 1532
                      +   +PS +TW T             +RL  G   C GRVE+ + GSWGT
Sbjct: 911  ---------EKRLASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGT 952

Query: 1533 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNG 1592
            VCDD WD +DA VVC+QLGCG A+ A   A+FGQG+GPI L++V+C G+ES LW CP   
Sbjct: 953  VCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARR 1012

Query: 1593 WLSHNCGHHEDAGVICSAAQSQSTPRPDT 1621
            W    CGH EDA V C+    Q TP+  T
Sbjct: 1013 WGHSECGHKEDAAVNCTDISVQKTPQKAT 1041



 Score =  896 bits (2315), Expect = 0.0
 Identities = 477/1143 (41%), Positives = 614/1143 (53%), Gaps = 162/1143 (14%)

Query: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
            LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 162  GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 221  PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
                     S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 155  ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205

Query: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
            +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 206  VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259

Query: 341  TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
                              + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 260  ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303

Query: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
            C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363

Query: 461  ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 520
             CS                          S L LRL  GG RC G VEV  +   G VCD
Sbjct: 364  TCS------------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399

Query: 521  DSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS 580
              W   +A+VVCRQLGCG A+           +    L    C+GNE+ LW C +  W  
Sbjct: 400  RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459

Query: 581  HNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 640
              C H E+A + CS        RLV G   C GRVEV +  +WG++CD  +    A+V+C
Sbjct: 460  LTCDHYEEAKITCSAHREP---RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLC 516

Query: 641  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 700
            R+L CG   S  G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV+
Sbjct: 517  RELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVV 576

Query: 701  CSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDD 760
            C    SR T                       +RLVNG   C+GRVE+   G+WG++C+ 
Sbjct: 577  C----SRYT----------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNS 610

Query: 761  SWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 820
             WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     + 
Sbjct: 611  HWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGAS 670

Query: 821  NCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLA-------LRLVNGGDRCQG 873
             C   + A VICS +QS+   S ++          PE S         LRLVNGG RC G
Sbjct: 671  LCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAG 730

Query: 874  RVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 933
            RVE+ + GSWGT+CDDSWD SDA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C+G
Sbjct: 731  RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790

Query: 934  YESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLAL 993
             ES +W C  +GW   NC+H EDAGVICS                            ++L
Sbjct: 791  KESRIWQCHSHGWGQQNCRHKEDAGVICS--------------------------EFMSL 824

Query: 994  RLVNGGDR--CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1051
            RL +   R  C GR+EV Y G+WGTV   S       VVCRQLGC         +     
Sbjct: 825  RLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAM 884

Query: 1052 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHA 1111
            S P+ +D+V+C      LW CP + W                  +   +PS +TW T   
Sbjct: 885  SIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDN 927

Query: 1112 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1171
                      +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A+ A
Sbjct: 928  K---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKA 978

Query: 1172 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1231
               A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP 
Sbjct: 979  FKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQ 1038

Query: 1232 PDT 1234
              T
Sbjct: 1039 KAT 1041



 Score =  896 bits (2315), Expect = 0.0
 Identities = 479/1141 (41%), Positives = 618/1141 (54%), Gaps = 161/1141 (14%)

Query: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152

Query: 353  STAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208

Query: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261

Query: 473  PDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 532
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304

Query: 533  RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVI 592
            +QLGC  A+ A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV 
Sbjct: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364

Query: 593  CSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA--TS 650
            CS   S L LRL  GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS
Sbjct: 365  CSDG-SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423

Query: 651  APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 710
                ++    +  + L    C+G+E+ LW C N  W    C H+E+A + CSA +     
Sbjct: 424  YQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP--- 478

Query: 711  RPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 770
                                   RLV G   C GRVEV +  +WG++CD  +    A+V+
Sbjct: 479  -----------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVL 515

Query: 771  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV 830
            CR+L CG   S  G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV
Sbjct: 516  CRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGV 575

Query: 831  ICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 890
            +CS                            +RLVNG   C+GRVE+   G+WG++C+  
Sbjct: 576  VCS------------------------RYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSH 611

Query: 891  WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 950
            WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +  
Sbjct: 612  WDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASL 671

Query: 951  CQHSEDAGVICSAAHSWSTPSPD------TLPTITLPASTVGSESSLALRLVNGGDRCQG 1004
            C   + A VICS   S +  S +      T PTI   ++    ES   LRLVNGG RC G
Sbjct: 672  CPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG-QLRLVNGGGRCAG 730

Query: 1005 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1064
            RVE+ ++GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G
Sbjct: 731  RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790

Query: 1065 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRL 1124
             ES +W C  +GW   NC H EDAGVICS                          ++LRL
Sbjct: 791  KESRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSLRL 826

Query: 1125 VNGGDR--CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG 1182
             +   R  C GR+EV Y G+WGTV           VVCRQLGC         +     S 
Sbjct: 827  TSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSI 886

Query: 1183 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHAST 1242
            P+ +D+V+C      LW CP + W                  +   +PS +TW T     
Sbjct: 887  PMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDNK- 928

Query: 1243 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1302
                    +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A  A  
Sbjct: 929  --------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFK 980

Query: 1303 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD 1362
             A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP   
Sbjct: 981  EAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKA 1040

Query: 1363 T 1363
            T
Sbjct: 1041 T 1041



 Score =  886 bits (2290), Expect = 0.0
 Identities = 480/1174 (40%), Positives = 621/1174 (52%), Gaps = 190/1174 (16%)

Query: 602  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 662  GPIVLDDVRCSGHESYLWSCPNNGWLSH-NCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
            G I +D V C G+ES LW C ++GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
                    S+L +RL  G + C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A 
Sbjct: 155  --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206

Query: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840
            S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS       
Sbjct: 207  SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG----- 261

Query: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304

Query: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960
            +QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV 
Sbjct: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364

Query: 961  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1020
            CS                          S L LRL  GG RC G VEV  Q   G VCD 
Sbjct: 365  CSDG------------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400

Query: 1021 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1080
             W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W   
Sbjct: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGL 460

Query: 1081 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140
             C H E+A + CSA +                          RLV G   C GRVEV + 
Sbjct: 461  TCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKHG 496

Query: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200
             +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L  
Sbjct: 497  DTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSL 556

Query: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1260
            CP        C H  D GV+CS                            +RLVNG   C
Sbjct: 557  CPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNGKTPC 592

Query: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320
            +GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A S PG ARFG+G+G I      C
Sbjct: 593  EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHC 652

Query: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHASTAGSESS 1377
            +G E ++  CP     +  C   + A VICS +QSQ   S ++    PT    T   ES+
Sbjct: 653  TGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR--PTIPEESA 710

Query: 1378 LA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1431
            +A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGCG A +A G
Sbjct: 711  VACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATG 770

Query: 1432 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD 1491
            +A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S       
Sbjct: 771  SAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS------- 823

Query: 1492 TWPTSRASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1549
                             LRL +   R  C GR+EV Y G+WGTV           VVCRQ
Sbjct: 824  -----------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQ 866

Query: 1550 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609
            LGC         +     S P+ +D+V+C      LW CP + W                
Sbjct: 867  LGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW---------------- 910

Query: 1610 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1669
              +  ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVCDDSW
Sbjct: 911  -EKRLASPSEETWITCDNK-----------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSW 958

Query: 1670 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1729
            D +DA VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W    C
Sbjct: 959  DLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSEC 1018

Query: 1730 GHHEDAGVICSATQINSTTTDWWHPTTTTTARPS 1763
            GH EDA V C+   +  T      P   TT R S
Sbjct: 1019 GHKEDAAVNCTDISVQKT------PQKATTGRSS 1046



 Score =  786 bits (2029), Expect = 0.0
 Identities = 423/1025 (41%), Positives = 554/1025 (54%), Gaps = 143/1025 (13%)

Query: 91   TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 150
            T ++GS+  L +RL  G   C GR+EI ++G WGTVCDD+++ + A+V+CRQL CG A+S
Sbjct: 150  TCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVS 207

Query: 151  APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTL 210
              G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS        
Sbjct: 208  FSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------ 261

Query: 211  RPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV 270
                               + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V
Sbjct: 262  -------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302

Query: 271  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAG 330
             C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAG
Sbjct: 303  ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362

Query: 331  VICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 390
            V CS                        S L LRL  GG RC G VEV  +   G VCD 
Sbjct: 363  VTCS----------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400

Query: 391  SWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
             W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +  W 
Sbjct: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWG 458

Query: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508
               C H E+A + CSA                              RLV G   C GRVE
Sbjct: 459  GLTCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCSGRVE 492

Query: 509  VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNES 568
            V +  +WG++CD  +    A+V+CR+L CG  +   G A FG+G+G I  ++ +C G+ES
Sbjct: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552

Query: 569  YLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 628
            +L  CP        C HS D GV+CS       +RLVNG   C+GRVE+   G+WG++C+
Sbjct: 553  HLSLCPVAPRPEGTCSHSRDVGVVCS---RYTEIRLVNGKTPCEGRVELKTLGAWGSLCN 609

Query: 629  DSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLS 688
              WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +
Sbjct: 610  SHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGA 669

Query: 689  HNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLT------LRLVNGSDRC 742
              C   + A VICS  QS++    ++ S     P T+  ES++       LRLVNG  RC
Sbjct: 670  SLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRP-TIPEESAVACIESGQLRLVNGGGRC 728

Query: 743  QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 802
             GRVE+ + GSWGT+CDDSWD +DA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C
Sbjct: 729  AGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKC 788

Query: 803  SGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLAL 862
            +G ES +W C  +GW   NC H EDAGVICS                          ++L
Sbjct: 789  NGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSL 824

Query: 863  RLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920
            RL +   R  C GR+EV Y G+WGTV   S   +   VVCRQLGC         +     
Sbjct: 825  RLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAM 884

Query: 921  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980
            S P+ +D+V+C      LW CP + W       SE+  + C                   
Sbjct: 885  SIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN----------------- 927

Query: 981  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040
                        +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+
Sbjct: 928  -----------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPAL 976

Query: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100
             A   A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    + T
Sbjct: 977  KAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKT 1036

Query: 1101 PSPDT 1105
            P   T
Sbjct: 1037 PQKAT 1041



 Score =  622 bits (1604), Expect = e-177
 Identities = 349/885 (39%), Positives = 453/885 (51%), Gaps = 136/885 (15%)

Query: 1122 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1181
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 1182 GPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1240
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 1241 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1300
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A S 
Sbjct: 155  ------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208

Query: 1301 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1360
             G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS         
Sbjct: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261

Query: 1361 PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1420
                           + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C+Q
Sbjct: 262  ---------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQ 306

Query: 1421 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
            LGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAGV CS
Sbjct: 307  LGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366

Query: 1481 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 1540
                                    S L LRL  GG RC G VEV  Q   G VCD  W  
Sbjct: 367  DG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGL 404

Query: 1541 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1600
             +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W    C H
Sbjct: 405  KEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDH 464

Query: 1601 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS 1660
            +E+A + CSA +                            RLV G   C GRVEV +  +
Sbjct: 465  YEEAKITCSAHREP--------------------------RLVGGDIPCSGRVEVKHGDT 498

Query: 1661 WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 1720
            WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G+ES+L  CP
Sbjct: 499  WGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCP 558

Query: 1721 HKGWLTHNCGHHEDAGVICSATQ----INSTTTDWWHPTTTTTARPSSNCGGFLFYASGT 1776
                    C H  D GV+CS       +N  T         T     S C          
Sbjct: 559  VAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAH 618

Query: 1777 FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFD---GSLNS 1833
                          KC   +    G R   G   +     H C+     + D    +L +
Sbjct: 619  VLC--------QQLKCGVALSTPGGARFGKGNGQIWRHMFH-CTGTEQHMGDCPVTALGA 669

Query: 1834 SL-----LLGKICNDTRQIFTSSYN-------RMTIHFRSDISFQNTGFLAWYNSFPSDA 1881
            SL     +   IC+  +    SS N       R TI   S ++   +G            
Sbjct: 670  SLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG------------ 717

Query: 1882 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF 1941
             LRLVN     G CAGRVEIYH G+WGT+CDDSW + +A VVCRQLGCG A++A G+A+F
Sbjct: 718  QLRLVN---GGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHF 774

Query: 1942 GSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            G G+GPI LD+++C+G ES +WQC + GW   NC H+EDAGVICS
Sbjct: 775  GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819



 Score =  621 bits (1602), Expect = e-177
 Identities = 376/1048 (35%), Positives = 512/1048 (48%), Gaps = 180/1048 (17%)

Query: 971  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 1025
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  Q  WGTVC++ W   
Sbjct: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83

Query: 1026 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGH 1084
              +V+C QLGC  A+ APG A    GSG I +D V C G+ES LW C H+GW  H NC H
Sbjct: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143

Query: 1085 SEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWG 1144
             +DAGV CS                        S+L +RL  GG+ C GR+E+ ++G WG
Sbjct: 144  QQDAGVTCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWG 181

Query: 1145 TVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHN 1204
            TVCDD ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H 
Sbjct: 182  TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241

Query: 1205 GWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 1264
            GW  HNC H EDAGVICS                        + L+LRLV+G   C GR+
Sbjct: 242  GWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRL 279

Query: 1265 EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 1324
            EV ++G WGT+CDD WD+ DA V C+QLGC  A +A G     +G G I LD V C GHE
Sbjct: 280  EVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHE 339

Query: 1325 SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVN 1384
              +W C H+ W  H C H+EDAGV CS                        S L LRL  
Sbjct: 340  PAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELRLRG 377

Query: 1385 GGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA--TSAPGNARFGQGSGPI 1442
            GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  +
Sbjct: 378  GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437

Query: 1443 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAG 1502
             L    C+G+E+ LW C +  W    C H+E+A + CSA +                   
Sbjct: 438  FLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP----------------- 478

Query: 1503 SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 1562
                   RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A
Sbjct: 479  -------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGA 531

Query: 1563 QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 1622
             FG+G+G I  ++ +C GHES+L  CP        C H  D GV+CS             
Sbjct: 532  HFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------- 582

Query: 1623 LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 1682
                             +RLVNG   C GRVE+   G+WG++C+  WD  DA+V+C+QL 
Sbjct: 583  -----------------IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLK 625

Query: 1683 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 1742
            CG A+S PG ARFG+G+G I      C+G E ++  CP        C   + A VICS  
Sbjct: 626  CGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGN 685

Query: 1743 Q---INSTTTDWWHPTTTTTARPSS----------------NCGGFL-FYASGTFSSPSY 1782
            Q   ++S  +    PT  T    S+                 C G +  Y  G++ +   
Sbjct: 686  QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICD 745

Query: 1783 PAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-C 1841
             ++  ++A  V   ++  G  IN   S     AH            G     + L ++ C
Sbjct: 746  DSWDLSDAHVVCR-QLGCGEAINATGS-----AHF-----------GEGTGPIWLDEMKC 788

Query: 1842 NDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAG 1897
            N       Q  +  + +     + D     + F++          LRL +  +S   CAG
Sbjct: 789  NGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS----------LRLTS-EASREACAG 837

Query: 1898 RVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSG 1957
            R+E+++ G WGTV   S +     VVCRQLGC         +   + S P+ +D+V+C  
Sbjct: 838  RLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPK 897

Query: 1958 TESTLWQCRNRGWFSHNCNHREDAGVIC 1985
               TLWQC +  W     +  E+  + C
Sbjct: 898  GPDTLWQCPSSPWEKRLASPSEETWITC 925



 Score =  414 bits (1064), Expect = e-115
 Identities = 223/529 (42%), Positives = 288/529 (54%), Gaps = 68/529 (12%)

Query: 80   SLIPSESTLESTVAEGSDSGLA------LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDT 133
            SL P     E T +   D G+       +RLVNG   C+GRVE+   G+WG++C+  WD 
Sbjct: 555  SLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDI 614

Query: 134  NDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGH 193
             DA+V+C+QL CG A+S PG A FG+G+G I      C+G E ++  CP     +  C  
Sbjct: 615  EDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPS 674

Query: 194  GEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLA------LRLVNGGDRCRGRV 247
             + A VICS  Q Q+     S    + P  PT   ES++A      LRLVNGG RC GRV
Sbjct: 675  EQVASVICSGNQSQTLSSCNS--SSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRV 732

Query: 248  EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 307
            E+ + GSWGT+CDD WD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G E
Sbjct: 733  EIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKE 792

Query: 308  SYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVN 367
            S +W C  +GW   NC H EDAGVICS                          ++LRL +
Sbjct: 793  SRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSLRLTS 828

Query: 368  GGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPI 425
               R  C GR+EV Y G+WGTV   S   +   VVCRQLGC         +     S P+
Sbjct: 829  EASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888

Query: 426  VLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAST 485
             +D+V+C      LW CP + W       SE+  + C                       
Sbjct: 889  WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN--------------------- 927

Query: 486  VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPG 545
                    +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+ A  
Sbjct: 928  -------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFK 980

Query: 546  NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
             A FGQG+GPI L++V+C GNES LW CP   W    CGH EDA V C+
Sbjct: 981  EAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029



 Score =  320 bits (820), Expect = 1e-86
 Identities = 178/436 (40%), Positives = 224/436 (51%), Gaps = 59/436 (13%)

Query: 42   PTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLA 101
            P  A G+       + S +  G+    +S   S+    SL P+  T+    A        
Sbjct: 663  PVTALGASLCPSEQVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQ 718

Query: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
            LRLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+
Sbjct: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT 778

Query: 162  GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
            GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                   
Sbjct: 779  GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------- 819

Query: 222  PVPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871

Query: 280  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914

Query: 340  PTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399
             +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA V
Sbjct: 915  ASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQV 965

Query: 400  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459
            VC+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA 
Sbjct: 966  VCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAA 1025

Query: 460  VICSAAHSWSTPSPDT 475
            V C+      TP   T
Sbjct: 1026 VNCTDISVQKTPQKAT 1041



 Score =  130 bits (328), Expect = 1e-29
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029



 Score =  108 bits (271), Expect = 5e-23
 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 4/109 (3%)

Query: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938
            +D  LRLV+  +    C+GRVE+     WGTVC++ W+++   V+C QLGC  A+ A G 
Sbjct: 47   TDKELRLVDGENK---CSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGW 103

Query: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH-NCNHREDAGVICS 1986
            A   +GSG I +D V C G ES LW C++ GW  H NC H++DAGV CS
Sbjct: 104  ANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1942
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639

Query: 1943 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1992
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425

Query: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1988
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475


>gi|44662834 CD163 antigen isoform a [Homo sapiens]
          Length = 1156

 Score =  901 bits (2328), Expect = 0.0
 Identities = 491/1169 (42%), Positives = 633/1169 (54%), Gaps = 171/1169 (14%)

Query: 472  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 526
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  +  WGTVC++ W   
Sbjct: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83

Query: 527  DANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSH-NCGH 585
              +V+C QLGC  A+ APG A    GSG I +D V C GNES LW C H+GW  H NC H
Sbjct: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143

Query: 586  SEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 645
             +DAGV CS   S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++ + A+V+CRQL C
Sbjct: 144  QQDAGVTCSDG-SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLEC 202

Query: 646  GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQ 705
            G A S  G++ FG+GSGPI  DD+ C+G+ES LW+C + GW  HNC H EDAGVICS   
Sbjct: 203  GSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG- 261

Query: 706  SRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTN 765
                                   + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ 
Sbjct: 262  -----------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSY 298

Query: 766  DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 825
            DA V C+QLGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+
Sbjct: 299  DAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHN 358

Query: 826  EDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGT 885
            EDAGV CS                        S L LRL  GG RC G VEV  +   G 
Sbjct: 359  EDAGVTCSDG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGK 396

Query: 886  VCDDSWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPH 943
            VCD  W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +
Sbjct: 397  VCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKN 454

Query: 944  NGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQ 1003
              W    C H E+A + CSA                              RLV G   C 
Sbjct: 455  WQWGGLTCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCS 488

Query: 1004 GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1063
            GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C 
Sbjct: 489  GRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCE 548

Query: 1064 GHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALR 1123
            GHES+L  CP        C HS D GV+CS                            +R
Sbjct: 549  GHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IR 584

Query: 1124 LVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 1183
            LVNG   C+GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A+S PG ARFG+G+G 
Sbjct: 585  LVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQ 644

Query: 1184 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHA 1240
            I      C+G E ++  CP     +  C   + A VICS +QSQ   S ++    PT   
Sbjct: 645  IWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR-- 702

Query: 1241 STAGSESSLA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1294
             T   ES++A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGC
Sbjct: 703  PTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGC 762

Query: 1295 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1354
            G A +A G+A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   
Sbjct: 763  GEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFM 822

Query: 1355 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDYWDTN 1412
            S                        LRL +   R  C GR+EV Y G+WGTV        
Sbjct: 823  S------------------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSET 858

Query: 1413 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 1472
               VVCRQLGC         +     S P+ +D+V+C      LW CP + W        
Sbjct: 859  TVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-------- 910

Query: 1473 EDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGT 1532
                      +   +PS +TW T             +RL  G   C GRVE+ + GSWGT
Sbjct: 911  ---------EKRLASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGT 952

Query: 1533 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNG 1592
            VCDD WD +DA VVC+QLGCG A+ A   A+FGQG+GPI L++V+C G+ES LW CP   
Sbjct: 953  VCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARR 1012

Query: 1593 WLSHNCGHHEDAGVICSAAQSQSTPRPDT 1621
            W    CGH EDA V C+    Q TP+  T
Sbjct: 1013 WGHSECGHKEDAAVNCTDISVQKTPQKAT 1041



 Score =  896 bits (2315), Expect = 0.0
 Identities = 477/1143 (41%), Positives = 614/1143 (53%), Gaps = 162/1143 (14%)

Query: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
            LRLV+G+ +C GRVE+  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 162  GPIALDDVRCSGHESYLWSCPHNGWLSH-NCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 221  PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
                     S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A
Sbjct: 155  ---------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSA 205

Query: 281  MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
            +S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H+EDAGVICS      
Sbjct: 206  VSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS------ 259

Query: 341  TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
                              + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V 
Sbjct: 260  ----------------KGADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVA 303

Query: 401  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
            C+QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV
Sbjct: 304  CKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGV 363

Query: 461  ICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 520
             CS                          S L LRL  GG RC G VEV  +   G VCD
Sbjct: 364  TCS------------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCD 399

Query: 521  DSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLS 580
              W   +A+VVCRQLGCG A+           +    L    C+GNE+ LW C +  W  
Sbjct: 400  RGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGG 459

Query: 581  HNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 640
              C H E+A + CS        RLV G   C GRVEV +  +WG++CD  +    A+V+C
Sbjct: 460  LTCDHYEEAKITCSAHREP---RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLC 516

Query: 641  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 700
            R+L CG   S  G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV+
Sbjct: 517  RELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVV 576

Query: 701  CSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDD 760
            C    SR T                       +RLVNG   C+GRVE+   G+WG++C+ 
Sbjct: 577  C----SRYT----------------------EIRLVNGKTPCEGRVELKTLGAWGSLCNS 610

Query: 761  SWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 820
             WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     + 
Sbjct: 611  HWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGAS 670

Query: 821  NCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLA-------LRLVNGGDRCQG 873
             C   + A VICS +QS+   S ++          PE S         LRLVNGG RC G
Sbjct: 671  LCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAG 730

Query: 874  RVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSG 933
            RVE+ + GSWGT+CDDSWD SDA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C+G
Sbjct: 731  RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790

Query: 934  YESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLAL 993
             ES +W C  +GW   NC+H EDAGVICS                            ++L
Sbjct: 791  KESRIWQCHSHGWGQQNCRHKEDAGVICS--------------------------EFMSL 824

Query: 994  RLVNGGDR--CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1051
            RL +   R  C GR+EV Y G+WGTV   S       VVCRQLGC         +     
Sbjct: 825  RLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAM 884

Query: 1052 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHA 1111
            S P+ +D+V+C      LW CP + W                  +   +PS +TW T   
Sbjct: 885  SIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDN 927

Query: 1112 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1171
                      +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A+ A
Sbjct: 928  K---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKA 978

Query: 1172 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1231
               A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP 
Sbjct: 979  FKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQ 1038

Query: 1232 PDT 1234
              T
Sbjct: 1039 KAT 1041



 Score =  896 bits (2315), Expect = 0.0
 Identities = 479/1141 (41%), Positives = 618/1141 (54%), Gaps = 161/1141 (14%)

Query: 234  LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 294  GPIVLDDVRCSGHESYLWSCPHNGWLTH-NCGHSEDAGVICSAPQSRPTPSPDTWPTSHA 352
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS------------------ 152

Query: 353  STAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD+++   A+V+CRQL CG A S 
Sbjct: 153  ----DGSNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208

Query: 413  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472
             G++ FG+GSGPI  DD+ C+G ES LW+C H GW  HNC H+EDAGVICS         
Sbjct: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261

Query: 473  PDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 532
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304

Query: 533  RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVI 592
            +QLGC  A+ A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV 
Sbjct: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364

Query: 593  CSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA--TS 650
            CS   S L LRL  GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS
Sbjct: 365  CSDG-SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTS 423

Query: 651  APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 710
                ++    +  + L    C+G+E+ LW C N  W    C H+E+A + CSA +     
Sbjct: 424  YQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP--- 478

Query: 711  RPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVV 770
                                   RLV G   C GRVEV +  +WG++CD  +    A+V+
Sbjct: 479  -----------------------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVL 515

Query: 771  CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGV 830
            CR+L CG   S  G A FG+G+G I  ++ +C GHES+L  CP        C H  D GV
Sbjct: 516  CRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGV 575

Query: 831  ICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDS 890
            +CS                            +RLVNG   C+GRVE+   G+WG++C+  
Sbjct: 576  VCS------------------------RYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSH 611

Query: 891  WDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN 950
            WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +  
Sbjct: 612  WDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASL 671

Query: 951  CQHSEDAGVICSAAHSWSTPSPD------TLPTITLPASTVGSESSLALRLVNGGDRCQG 1004
            C   + A VICS   S +  S +      T PTI   ++    ES   LRLVNGG RC G
Sbjct: 672  CPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG-QLRLVNGGGRCAG 730

Query: 1005 RVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1064
            RVE+ ++GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G
Sbjct: 731  RVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNG 790

Query: 1065 HESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRL 1124
             ES +W C  +GW   NC H EDAGVICS                          ++LRL
Sbjct: 791  KESRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSLRL 826

Query: 1125 VNGGDR--CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG 1182
             +   R  C GR+EV Y G+WGTV           VVCRQLGC         +     S 
Sbjct: 827  TSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSI 886

Query: 1183 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHAST 1242
            P+ +D+V+C      LW CP + W                  +   +PS +TW T     
Sbjct: 887  PMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRLASPSEETWITCDNK- 928

Query: 1243 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1302
                    +RL  G   C GRVE+ + GSWGTVCDD WD +DA VVC+QLGCG A  A  
Sbjct: 929  --------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFK 980

Query: 1303 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD 1362
             A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    Q TP   
Sbjct: 981  EAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKTPQKA 1040

Query: 1363 T 1363
            T
Sbjct: 1041 T 1041



 Score =  886 bits (2290), Expect = 0.0
 Identities = 480/1174 (40%), Positives = 621/1174 (52%), Gaps = 190/1174 (16%)

Query: 602  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A  APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 662  GPIVLDDVRCSGHESYLWSCPNNGWLSH-NCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
            G I +D V C G+ES LW C ++GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
                    S+L +RL  G + C GR+E+ ++G WGTVCDD+++ + A+V+CRQL CG A 
Sbjct: 155  --------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAV 206

Query: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840
            S  G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS       
Sbjct: 207  SFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG----- 261

Query: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900
                             + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C
Sbjct: 262  -----------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVAC 304

Query: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960
            +QLGC  A +A G     +G G I LD V C G+E  +W C H+ W  H C H+EDAGV 
Sbjct: 305  KQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVT 364

Query: 961  CSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDD 1020
            CS                          S L LRL  GG RC G VEV  Q   G VCD 
Sbjct: 365  CSDG------------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400

Query: 1021 SWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH 1080
             W   +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W   
Sbjct: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGL 460

Query: 1081 NCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYR 1140
             C H E+A + CSA +                          RLV G   C GRVEV + 
Sbjct: 461  TCDHYEEAKITCSAHREP------------------------RLVGGDIPCSGRVEVKHG 496

Query: 1141 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWS 1200
             +WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C GHES+L  
Sbjct: 497  DTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSL 556

Query: 1201 CPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRC 1260
            CP        C H  D GV+CS                            +RLVNG   C
Sbjct: 557  CPVAPRPEGTCSHSRDVGVVCSRYTE------------------------IRLVNGKTPC 592

Query: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320
            +GRVE+   G+WG++C+ +WD  DA+V+C+QL CG A S PG ARFG+G+G I      C
Sbjct: 593  EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHC 652

Query: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT---WPTSHASTAGSESS 1377
            +G E ++  CP     +  C   + A VICS +QSQ   S ++    PT    T   ES+
Sbjct: 653  TGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTR--PTIPEESA 710

Query: 1378 LA------LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1431
            +A      LRLVNGG RC GRVE+ + GSWGT+CDD WD +DA+VVCRQLGCG A +A G
Sbjct: 711  VACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATG 770

Query: 1432 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPD 1491
            +A FG+G+GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS   S       
Sbjct: 771  SAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS------- 823

Query: 1492 TWPTSRASTAGSESTLALRLVNGGDR--CRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1549
                             LRL +   R  C GR+EV Y G+WGTV           VVCRQ
Sbjct: 824  -----------------LRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQ 866

Query: 1550 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609
            LGC         +     S P+ +D+V+C      LW CP + W                
Sbjct: 867  LGCADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW---------------- 910

Query: 1610 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1669
              +  ++P  +TW+T +             +RL  G   C GRVE+ + GSWGTVCDDSW
Sbjct: 911  -EKRLASPSEETWITCDNK-----------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSW 958

Query: 1670 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1729
            D +DA VVC+QLGCG A+ A   A FGQG+GPI L++V+C GNES LW CP + W    C
Sbjct: 959  DLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSEC 1018

Query: 1730 GHHEDAGVICSATQINSTTTDWWHPTTTTTARPS 1763
            GH EDA V C+   +  T      P   TT R S
Sbjct: 1019 GHKEDAAVNCTDISVQKT------PQKATTGRSS 1046



 Score =  786 bits (2029), Expect = 0.0
 Identities = 423/1025 (41%), Positives = 554/1025 (54%), Gaps = 143/1025 (13%)

Query: 91   TVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMS 150
            T ++GS+  L +RL  G   C GR+EI ++G WGTVCDD+++ + A+V+CRQL CG A+S
Sbjct: 150  TCSDGSN--LEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVS 207

Query: 151  APGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTL 210
              G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS        
Sbjct: 208  FSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------ 261

Query: 211  RPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANV 270
                               + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V
Sbjct: 262  -------------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAV 302

Query: 271  VCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAG 330
             C+QLGC  A++A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAG
Sbjct: 303  ACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAG 362

Query: 331  VICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 390
            V CS                        S L LRL  GG RC G VEV  +   G VCD 
Sbjct: 363  VTCS----------------------DGSDLELRLRGGGSRCAGTVEVEIQRLLGKVCDR 400

Query: 391  SWDTSDANVVCRQLGCGWA--TSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
             W   +A+VVCRQLGCG A  TS    ++    +  + L    C+G E+ LW C +  W 
Sbjct: 401  GWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSS--CNGNETSLWDCKNWQWG 458

Query: 449  SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508
               C H E+A + CSA                              RLV G   C GRVE
Sbjct: 459  GLTCDHYEEAKITCSAHRE--------------------------PRLVGGDIPCSGRVE 492

Query: 509  VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNES 568
            V +  +WG++CD  +    A+V+CR+L CG  +   G A FG+G+G I  ++ +C G+ES
Sbjct: 493  VKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHES 552

Query: 569  YLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 628
            +L  CP        C HS D GV+CS       +RLVNG   C+GRVE+   G+WG++C+
Sbjct: 553  HLSLCPVAPRPEGTCSHSRDVGVVCS---RYTEIRLVNGKTPCEGRVELKTLGAWGSLCN 609

Query: 629  DSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLS 688
              WD  DA+V+C+QL CG A S PG ARFG+G+G I      C+G E ++  CP     +
Sbjct: 610  SHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGA 669

Query: 689  HNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLT------LRLVNGSDRC 742
              C   + A VICS  QS++    ++ S     P T+  ES++       LRLVNG  RC
Sbjct: 670  SLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRP-TIPEESAVACIESGQLRLVNGGGRC 728

Query: 743  QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 802
             GRVE+ + GSWGT+CDDSWD +DA+VVCRQLGCG A +A G+A FG+G+GPI LD+++C
Sbjct: 729  AGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKC 788

Query: 803  SGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSLAL 862
            +G ES +W C  +GW   NC H EDAGVICS                          ++L
Sbjct: 789  NGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSL 824

Query: 863  RLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920
            RL +   R  C GR+EV Y G+WGTV   S   +   VVCRQLGC         +     
Sbjct: 825  RLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAM 884

Query: 921  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980
            S P+ +D+V+C      LW CP + W       SE+  + C                   
Sbjct: 885  SIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN----------------- 927

Query: 981  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040
                        +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+
Sbjct: 928  -----------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPAL 976

Query: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100
             A   A FGQG+GPI L++V+C G+ES LW CP   W    CGH EDA V C+    + T
Sbjct: 977  KAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCTDISVQKT 1036

Query: 1101 PSPDT 1105
            P   T
Sbjct: 1037 PQKAT 1041



 Score =  622 bits (1604), Expect = e-177
 Identities = 349/885 (39%), Positives = 453/885 (51%), Gaps = 136/885 (15%)

Query: 1122 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1181
            LRLV+G ++C GRVEV  +  WGTVC++ W     +V+C QLGC  A+ APG A    GS
Sbjct: 51   LRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSSAGS 110

Query: 1182 GPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1240
            G I +D V C G+ES LW C H+GW  H NC H +DAGV CS                  
Sbjct: 111  GRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCSDG---------------- 154

Query: 1241 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1300
                  S+L +RL  GG+ C GR+E+ ++G WGTVCDD ++ + A+V+CRQL CG A S 
Sbjct: 155  ------SNLEMRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSF 208

Query: 1301 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1360
             G++ FG+GSGPI  DD+ C+G+ES LW+C H GW  HNC H EDAGVICS         
Sbjct: 209  SGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICSKG------- 261

Query: 1361 PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1420
                           + L+LRLV+G   C GR+EV ++G WGT+CDD WD+ DA V C+Q
Sbjct: 262  ---------------ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQ 306

Query: 1421 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
            LGC  A +A G     +G G I LD V C GHE  +W C H+ W  H C H+EDAGV CS
Sbjct: 307  LGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS 366

Query: 1481 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 1540
                                    S L LRL  GG RC G VEV  Q   G VCD  W  
Sbjct: 367  DG----------------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGL 404

Query: 1541 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1600
             +A+VVCRQLGCG A+           +    L    C+G+E+ LW C +  W    C H
Sbjct: 405  KEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDH 464

Query: 1601 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS 1660
            +E+A + CSA +                            RLV G   C GRVEV +  +
Sbjct: 465  YEEAKITCSAHREP--------------------------RLVGGDIPCSGRVEVKHGDT 498

Query: 1661 WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP 1720
            WG++CD  +    A+V+CR+L CG  +S  G A FG+G+G I  ++ +C G+ES+L  CP
Sbjct: 499  WGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEFQCEGHESHLSLCP 558

Query: 1721 HKGWLTHNCGHHEDAGVICSATQ----INSTTTDWWHPTTTTTARPSSNCGGFLFYASGT 1776
                    C H  D GV+CS       +N  T         T     S C          
Sbjct: 559  VAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAH 618

Query: 1777 FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFD---GSLNS 1833
                          KC   +    G R   G   +     H C+     + D    +L +
Sbjct: 619  VLC--------QQLKCGVALSTPGGARFGKGNGQIWRHMFH-CTGTEQHMGDCPVTALGA 669

Query: 1834 SL-----LLGKICNDTRQIFTSSYN-------RMTIHFRSDISFQNTGFLAWYNSFPSDA 1881
            SL     +   IC+  +    SS N       R TI   S ++   +G            
Sbjct: 670  SLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESG------------ 717

Query: 1882 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF 1941
             LRLVN     G CAGRVEIYH G+WGT+CDDSW + +A VVCRQLGCG A++A G+A+F
Sbjct: 718  QLRLVN---GGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHF 774

Query: 1942 GSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            G G+GPI LD+++C+G ES +WQC + GW   NC H+EDAGVICS
Sbjct: 775  GEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS 819



 Score =  621 bits (1602), Expect = e-177
 Identities = 376/1048 (35%), Positives = 512/1048 (48%), Gaps = 180/1048 (17%)

Query: 971  SPDTLPTITLPASTVGSESSLA-----LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTN 1025
            SP T+ T+ L  S     SSL      LRLV+G ++C GRVEV  Q  WGTVC++ W   
Sbjct: 25   SPFTI-TVVLLLSACFVTSSLGGTDKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSME 83

Query: 1026 DANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSH-NCGH 1084
              +V+C QLGC  A+ APG A    GSG I +D V C G+ES LW C H+GW  H NC H
Sbjct: 84   AVSVICNQLGCPTAIKAPGWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTH 143

Query: 1085 SEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWG 1144
             +DAGV CS                        S+L +RL  GG+ C GR+E+ ++G WG
Sbjct: 144  QQDAGVTCSDG----------------------SNLEMRLTRGGNMCSGRIEIKFQGRWG 181

Query: 1145 TVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHN 1204
            TVCDD ++ + A+V+CRQL CG A+S  G++ FG+GSGPI  DD+ C+G+ES LW+C H 
Sbjct: 182  TVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQ 241

Query: 1205 GWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 1264
            GW  HNC H EDAGVICS                        + L+LRLV+G   C GR+
Sbjct: 242  GWGKHNCDHAEDAGVICSKG----------------------ADLSLRLVDGVTECSGRL 279

Query: 1265 EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 1324
            EV ++G WGT+CDD WD+ DA V C+QLGC  A +A G     +G G I LD V C GHE
Sbjct: 280  EVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQGHE 339

Query: 1325 SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVN 1384
              +W C H+ W  H C H+EDAGV CS                        S L LRL  
Sbjct: 340  PAVWQCKHHEWGKHYCNHNEDAGVTCSDG----------------------SDLELRLRG 377

Query: 1385 GGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA--TSAPGNARFGQGSGPI 1442
            GG RC G VEV  +   G VCD  W   +A+VVCRQLGCG A  TS    ++    +  +
Sbjct: 378  GGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWL 437

Query: 1443 VLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAG 1502
             L    C+G+E+ LW C +  W    C H+E+A + CSA +                   
Sbjct: 438  FLSS--CNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREP----------------- 478

Query: 1503 SESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNA 1562
                   RLV G   C GRVEV +  +WG++CD  +    A+V+CR+L CG  +S  G A
Sbjct: 479  -------RLVGGDIPCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGA 531

Query: 1563 QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTW 1622
             FG+G+G I  ++ +C GHES+L  CP        C H  D GV+CS             
Sbjct: 532  HFGEGNGQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCSRYTE--------- 582

Query: 1623 LTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 1682
                             +RLVNG   C GRVE+   G+WG++C+  WD  DA+V+C+QL 
Sbjct: 583  -----------------IRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLK 625

Query: 1683 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT 1742
            CG A+S PG ARFG+G+G I      C+G E ++  CP        C   + A VICS  
Sbjct: 626  CGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGN 685

Query: 1743 Q---INSTTTDWWHPTTTTTARPSS----------------NCGGFL-FYASGTFSSPSY 1782
            Q   ++S  +    PT  T    S+                 C G +  Y  G++ +   
Sbjct: 686  QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICD 745

Query: 1783 PAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKI-C 1841
             ++  ++A  V   ++  G  IN   S     AH            G     + L ++ C
Sbjct: 746  DSWDLSDAHVVCR-QLGCGEAINATGS-----AHF-----------GEGTGPIWLDEMKC 788

Query: 1842 NDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAG 1897
            N       Q  +  + +     + D     + F++          LRL +  +S   CAG
Sbjct: 789  NGKESRIWQCHSHGWGQQNCRHKEDAGVICSEFMS----------LRLTS-EASREACAG 837

Query: 1898 RVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSG 1957
            R+E+++ G WGTV   S +     VVCRQLGC         +   + S P+ +D+V+C  
Sbjct: 838  RLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVDNVQCPK 897

Query: 1958 TESTLWQCRNRGWFSHNCNHREDAGVIC 1985
               TLWQC +  W     +  E+  + C
Sbjct: 898  GPDTLWQCPSSPWEKRLASPSEETWITC 925



 Score =  414 bits (1064), Expect = e-115
 Identities = 223/529 (42%), Positives = 288/529 (54%), Gaps = 68/529 (12%)

Query: 80   SLIPSESTLESTVAEGSDSGLA------LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDT 133
            SL P     E T +   D G+       +RLVNG   C+GRVE+   G+WG++C+  WD 
Sbjct: 555  SLCPVAPRPEGTCSHSRDVGVVCSRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDI 614

Query: 134  NDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGH 193
             DA+V+C+QL CG A+S PG A FG+G+G I      C+G E ++  CP     +  C  
Sbjct: 615  EDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPS 674

Query: 194  GEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLA------LRLVNGGDRCRGRV 247
             + A VICS  Q Q+     S    + P  PT   ES++A      LRLVNGG RC GRV
Sbjct: 675  EQVASVICSGNQSQTLSSCNS--SSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRV 732

Query: 248  EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHE 307
            E+ + GSWGT+CDD WD +DA+VVCRQLGCG A++A G+A FG+G+GPI LD+++C+G E
Sbjct: 733  EIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKE 792

Query: 308  SYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVN 367
            S +W C  +GW   NC H EDAGVICS                          ++LRL +
Sbjct: 793  SRIWQCHSHGWGQQNCRHKEDAGVICS------------------------EFMSLRLTS 828

Query: 368  GGDR--CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPI 425
               R  C GR+EV Y G+WGTV   S   +   VVCRQLGC         +     S P+
Sbjct: 829  EASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPM 888

Query: 426  VLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAST 485
             +D+V+C      LW CP + W       SE+  + C                       
Sbjct: 889  WVDNVQCPKGPDTLWQCPSSPWEKRLASPSEETWITCDN--------------------- 927

Query: 486  VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPG 545
                    +RL  G   C GRVE+ + GSWGTVCDDSWD +DA VVC+QLGCG A+ A  
Sbjct: 928  -------KIRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFK 980

Query: 546  NARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
             A FGQG+GPI L++V+C GNES LW CP   W    CGH EDA V C+
Sbjct: 981  EAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029



 Score =  320 bits (820), Expect = 1e-86
 Identities = 178/436 (40%), Positives = 224/436 (51%), Gaps = 59/436 (13%)

Query: 42   PTVAEGSPFPSESTLESTVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLA 101
            P  A G+       + S +  G+    +S   S+    SL P+  T+    A        
Sbjct: 663  PVTALGASLCPSEQVASVICSGN----QSQTLSSCNSSSLGPTRPTIPEESAVACIESGQ 718

Query: 102  LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
            LRLVNG GRC GRVEI + GSWGT+CDDSWD +DA+VVCRQLGCG A++A G+A FG+G+
Sbjct: 719  LRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT 778

Query: 162  GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
            GPI LD+++C+G ES +W C  +GW   NC H EDAGVICS                   
Sbjct: 779  GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVICS------------------- 819

Query: 222  PVPTEGSESSLALRLVNGGDR--CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
                      ++LRL +   R  C GR+EV Y G+WGTV           VVCRQLGC  
Sbjct: 820  --------EFMSLRLTSEASREACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD 871

Query: 280  AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
                   +     S P+ +D+V+C      LW CP + W                  +  
Sbjct: 872  KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPW-----------------EKRL 914

Query: 340  PTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANV 399
             +PS +TW T             +RL  G   C GRVE+ + GSWGTVCDDSWD  DA V
Sbjct: 915  ASPSEETWITCDNK---------IRLQEGPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQV 965

Query: 400  VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAG 459
            VC+QLGCG A  A   A FGQG+GPI L++V+C G ES LW CP   W    C H EDA 
Sbjct: 966  VCQQLGCGPALKAFKEAEFGQGTGPIWLNEVKCKGNESSLWDCPARRWGHSECGHKEDAA 1025

Query: 460  VICSAAHSWSTPSPDT 475
            V C+      TP   T
Sbjct: 1026 VNCTDISVQKTPQKAT 1041



 Score =  130 bits (328), Expect = 1e-29
 Identities = 54/92 (58%), Positives = 69/92 (75%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
            C+GRVEI+HGG+WGTVCDDSW + +A+VVC+QLGCG A+ A   A FG G+GPI L++V+
Sbjct: 938  CSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEVK 997

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            C G ES+LW C  R W    C H+EDA V C+
Sbjct: 998  CKGNESSLWDCPARRWGHSECGHKEDAAVNCT 1029



 Score =  108 bits (271), Expect = 5e-23
 Identities = 51/109 (46%), Positives = 69/109 (63%), Gaps = 4/109 (3%)

Query: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938
            +D  LRLV+  +    C+GRVE+     WGTVC++ W+++   V+C QLGC  A+ A G 
Sbjct: 47   TDKELRLVDGENK---CSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGW 103

Query: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSH-NCNHREDAGVICS 1986
            A   +GSG I +D V C G ES LW C++ GW  H NC H++DAGV CS
Sbjct: 104  ANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTCS 152



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 45/110 (40%), Positives = 61/110 (55%), Gaps = 3/110 (2%)

Query: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1942
            +RLVN  +    C GRVE+   G WG++C+  W I++A V+C+QL CG A+S  G A FG
Sbjct: 583  IRLVNGKTP---CEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639

Query: 1943 SGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1992
             G+G I      C+GTE  +  C      +  C   + A VICSGN   T
Sbjct: 640  KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 44/110 (40%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938
            SD  LRL    S    CAG VE+      G VCD  W ++EA+VVCRQLGCG A+     
Sbjct: 369  SDLELRLRGGGSR---CAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQ 425

Query: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1988
             Y    +    L    C+G E++LW C+N  W    C+H E+A + CS +
Sbjct: 426  VYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAH 475


>gi|18152779 scavenger receptor cysteine rich domain containing, group
            B (4 domains) [Homo sapiens]
          Length = 575

 Score =  515 bits (1327), Expect = e-145
 Identities = 262/534 (49%), Positives = 314/534 (58%), Gaps = 28/534 (5%)

Query: 847  PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 906
            P + A    P     LRLV G  RC+GR+EV++ GSWG+VCDD WD  DANVVCRQLGCG
Sbjct: 43   PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG 102

Query: 907  WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 966
             A   P    FGQG GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C     
Sbjct: 103  LALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162

Query: 967  WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTND 1026
               P+   L +   P +    +S  ++RLV G + CQGRVE+L+ G WGTVCDD W   D
Sbjct: 163  TQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD 222

Query: 1027 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSE 1086
            A VVCRQLGCG AM+A  NA FG G+G I+LD+V C G E  L +C   GW  HNCGH E
Sbjct: 223  AAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHE 282

Query: 1087 DAGVIC--------------------------SASQSRPTPSPDTWPTSHASTAGSESSL 1120
            DAG +C                          SA+   P PS +T   + A+ A  + S 
Sbjct: 283  DAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG 342

Query: 1121 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1180
             LRLV G   C+GRVEVL+ G WGTVCDD WD  DA V CR+ GCG A+ A G   FG G
Sbjct: 343  RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402

Query: 1181 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSH 1239
             GP++LD+V C+G E+ L  C H GW  HNCGHHEDAG +C+  +        D   T+ 
Sbjct: 403  RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTR 462

Query: 1240 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 1299
              T        LRLVNG  RC+GRVE+     WGTVCDD WD   A V+CRQLGCG A +
Sbjct: 463  VPTPRPRDG-HLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALA 521

Query: 1300 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1353
            APG A FG G GPI+LD+V+C G ES L  C H  W +HNC H EDA V+C  S
Sbjct: 522  APGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575



 Score =  514 bits (1323), Expect = e-145
 Identities = 257/521 (49%), Positives = 312/521 (59%), Gaps = 30/521 (5%)

Query: 602  LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661
            LRLV G  RC+GR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A   P    FGQG 
Sbjct: 58   LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 662  GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLP 721
            GPI+LD+V C G E+ L  C + GW  HNC H+ED  V+C        P    L++   P
Sbjct: 118  GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177

Query: 722  PSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 781
             +    +S  ++RLV G++ CQGRVE+L+ G WGTVCDD W   DA VVCRQLGCG A +
Sbjct: 178  TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237

Query: 782  APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC--------- 832
            A  NA FG G+G I+LD+V C G E  L +C   GW  HNCGHHEDAG +C         
Sbjct: 238  ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297

Query: 833  -----------------SVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRV 875
                             S +   P PS +T   + A+ A  + S  LRLV G   C+GRV
Sbjct: 298  ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357

Query: 876  EVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYE 935
            EVL+ G WGTVCDD WD +DA V CR+ GCG A  A G   FG G GP++LD+V C+G E
Sbjct: 358  EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417

Query: 936  SYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTP-SPDTLPTITLPASTVGSESSLALR 994
            + L  C H GW  HNC H EDAG +C+           D   T  +P           LR
Sbjct: 418  ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGH---LR 474

Query: 995  LVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGP 1054
            LVNG  RC+GRVE+     WGTVCDD+WD   A V+CRQLGCG A++APG A FG G GP
Sbjct: 475  LVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGP 534

Query: 1055 IVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSAS 1095
            I+LD+V+C G ES L  C H  W +HNC HSEDA V+C  S
Sbjct: 535  ILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575



 Score =  512 bits (1318), Expect = e-144
 Identities = 266/546 (48%), Positives = 317/546 (58%), Gaps = 47/546 (8%)

Query: 1223 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1282
            AS  QPTP P                  LRLV G  RC+GR+EV++ GSWG+VCDD WD 
Sbjct: 45   ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89

Query: 1283 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1342
             DANVVCRQLGCG A   P    FGQG GPI+LD+V C G E+ L  C   GW  HNC H
Sbjct: 90   VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149

Query: 1343 HEDAGVICSA--SQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGS 1400
            +ED  V+C        PT    T      +    +S  ++RLV G + CQGRVE+L+ G 
Sbjct: 150  YEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGL 209

Query: 1401 WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP 1460
            WGTVCDD W   DA VVCRQLGCG A +A  NA FG G+G I+LD+V C G E  L +C 
Sbjct: 210  WGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQ 269

Query: 1461 HNGWLSHNCGHHEDAGVIC--------------------------SASQSQPTPSPDTWP 1494
              GW  HNCGHHEDAG +C                          SA+   P PS +T  
Sbjct: 270  SLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETAL 329

Query: 1495 TSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGW 1554
             + A+ A  + +  LRLV G   CRGRVEVL+ G WGTVCDD WD  DA V CR+ GCG 
Sbjct: 330  LTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGP 389

Query: 1555 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQ 1614
            A+ A G   FG G GP++LD+V C+G E+ L  C H GW  HNCGHHEDAG +C+  +  
Sbjct: 390  ALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEEL 449

Query: 1615 STP-RPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTND 1673
                + D   TT +P           LRLVNG  RC GRVE+     WGTVCDD+WD   
Sbjct: 450  GLQVQQDGSETTRVP---TPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRA 506

Query: 1674 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHE 1733
            A V+CRQLGCG A++APG A FG G GPI+LD+V+C G ES L  C H  W  HNC H E
Sbjct: 507  AGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSE 566

Query: 1734 DAGVIC 1739
            DA V+C
Sbjct: 567  DASVLC 572



 Score =  511 bits (1315), Expect = e-144
 Identities = 260/519 (50%), Positives = 309/519 (59%), Gaps = 30/519 (5%)

Query: 993  LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1052
            LRLV G  RC+GR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A+  P    FGQG 
Sbjct: 58   LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 1053 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSA--SQSRPTPSPDTWPTSH 1110
            GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C        PT    T     
Sbjct: 118  GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177

Query: 1111 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1170
             +    +S  ++RLV G + CQGRVE+L+ G WGTVCDD W   DA VVCRQLGCG AM+
Sbjct: 178  TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237

Query: 1171 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC--------- 1221
            A  NA FG G+G I+LD+V C G E  L +C   GW  HNCGHHEDAG +C         
Sbjct: 238  ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297

Query: 1222 -----------------SASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRV 1264
                             SA+   P PS +T   + A+ A  + S  LRLV G   C+GRV
Sbjct: 298  ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357

Query: 1265 EVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 1324
            EVL+ G WGTVCDD WD  DA V CR+ GCG A  A G   FG G GP++LD+V C+G E
Sbjct: 358  EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417

Query: 1325 SYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP-SPDTWPTSHASTAGSESSLALRLV 1383
            + L  C H GW  HNCGHHEDAG +C+  +        D   T+   T        LRLV
Sbjct: 418  ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476

Query: 1384 NGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIV 1443
            NG  RC+GRVE+     WGTVCDD WD   A V+CRQLGCG A +APG A FG G GPI+
Sbjct: 477  NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536

Query: 1444 LDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1482
            LD+V+C G ES L  C H  W +HNC H EDA V+C  S
Sbjct: 537  LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575



 Score =  506 bits (1303), Expect = e-142
 Identities = 261/540 (48%), Positives = 315/540 (58%), Gaps = 35/540 (6%)

Query: 81  LIPSESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVC 140
           L+P  S L+ T     +    LRLV G  RC+GR+E+++ GSWG+VCDD WD  DANVVC
Sbjct: 41  LLPLASALQPTPLPFQE----LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVC 96

Query: 141 RQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVI 200
           RQLGCG A+  P    FGQG GPI LD+V C G E+ L  C   GW  HNC H ED  V+
Sbjct: 97  RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156

Query: 201 CSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCD 260
           C    P      +    R +PP      +S  ++RLV G + C+GRVE+L+ G WGTVCD
Sbjct: 157 CDEFLPTQPPTRKMLTSR-APPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCD 215

Query: 261 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLT 320
           D W   DA VVCRQLGCG AM+A  NA FG G+G I+LD+V C G E  L +C   GW  
Sbjct: 216 DDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGV 275

Query: 321 HNCGHSEDAGVIC--------------------------SAPQSRPTPSPDTWPTSHAST 354
           HNCGH EDAG +C                          SA    P PS +T   + A+ 
Sbjct: 276 HNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAW 335

Query: 355 AGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
           A  + S  LRLV G   C+GRVEVL+ G WGTVCDD WD +DA V CR+ GCG A  A G
Sbjct: 336 AAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395

Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTP-SP 473
              FG G GP++LD+V C+G E+ L  C H GW  HNC H EDAG +C+           
Sbjct: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQ 455

Query: 474 DTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 533
           D   T  +P           LRLVNG  RC+GRVE+     WGTVCDD+WD   A V+CR
Sbjct: 456 DGSETTRVPTPRPRDGH---LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCR 512

Query: 534 QLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVIC 593
           QLGCG A+ APG A FG G GPI+LD+V+C G ES L  C H  W +HNC HSEDA V+C
Sbjct: 513 QLGCGQALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  503 bits (1296), Expect = e-142
 Identities = 255/516 (49%), Positives = 308/516 (59%), Gaps = 49/516 (9%)

Query: 494 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 553
           LRLV G  RC+GR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A+  P    FGQG 
Sbjct: 58  LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 554 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS----------------GPE 597
           GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C                  P 
Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177

Query: 598 SSL-------ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 650
           ++L       ++RLV G + CQGRVE+L+ G WGTVCDD W   DA VVCRQLGCG A +
Sbjct: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237

Query: 651 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC--------S 702
           A  NA FG G+G I+LD+V C G E  L +C + GW  HNCGHHEDAG +C        +
Sbjct: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297

Query: 703 AAQSRST----------------PRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRV 746
           A  S +T                P+P   + +    +    + S  LRLV G   C+GRV
Sbjct: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357

Query: 747 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHE 806
           EVL+ G WGTVCDD WD  DA V CR+ GCG A  A G   FG G GP++LD+V C+G E
Sbjct: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417

Query: 807 SYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTP-SPDTWPTSHASTAGPESSLALRLV 865
           + L  C H GW  HNCGHHEDAG +C+  +        D   T+   T  P     LRLV
Sbjct: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDG-HLRLV 476

Query: 866 NGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIV 925
           NG  RC+GRVE+     WGTVCDD+WD   A V+CRQLGCG A +APG A FG G GPI+
Sbjct: 477 NGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPIL 536

Query: 926 LDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 961
           LD+V+C G ES L  C H  W +HNC HSEDA V+C
Sbjct: 537 LDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  501 bits (1291), Expect = e-141
 Identities = 253/515 (49%), Positives = 302/515 (58%), Gaps = 47/515 (9%)

Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
           LRLV G  RCRGR+EV++ GSWG+VCDD WD  DANVVCRQLGCG A+  P    FGQG 
Sbjct: 58  LRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117

Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSA--PQSRPTPSPDTWPTSH 351
           GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C    P   PT    T     
Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPP 177

Query: 352 ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
            +    +S  ++RLV G + CQGRVE+L+ G WGTVCDD W   DA VVCRQLGCG A +
Sbjct: 178 TTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMA 237

Query: 412 APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAH----- 466
           A  NA FG G+G I+LD+V C G E  L +C   GW  HNC H EDAG +C+        
Sbjct: 238 ATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLT 297

Query: 467 -----------SWST--------PSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRV 507
                      +W T        P P     +   A+    + S  LRLV G   C+GRV
Sbjct: 298 ALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRV 357

Query: 508 EVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNE 567
           EVL+ G WGTVCDD WD  DA V CR+ GCG A+ A G   FG G GP++LD+V C+G E
Sbjct: 358 EVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTE 417

Query: 568 SYLWSCPHNGWLSHNCGHSEDAGVICSGPES---------------------SLALRLVN 606
           + L  C H GW  HNCGH EDAG +C+GPE                         LRLVN
Sbjct: 418 ARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPRPRDGHLRLVN 477

Query: 607 GGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVL 666
           G  RC+GRVE+     WGTVCDD+WD   A V+CRQLGCG A +APG A FG G GPI+L
Sbjct: 478 GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILL 537

Query: 667 DDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 701
           D+V+C G ES L  C +  W +HNC H EDA V+C
Sbjct: 538 DNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  501 bits (1289), Expect = e-141
 Identities = 256/535 (47%), Positives = 306/535 (57%), Gaps = 49/535 (9%)

Query: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
           P + A    P     LRLV G  RC+GR+EV++ GSWG+VCDD WD  DANVVCRQLGCG
Sbjct: 43  PLASALQPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCG 102

Query: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
            A   P    FGQG GPI+LD+V C G E+ L  C   GW  HNC H ED  V+C     
Sbjct: 103 LALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLP 162

Query: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTND 527
              P+   L +   P +    +S  ++RLV G + CQGRVE+L+ G WGTVCDD W   D
Sbjct: 163 TQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPD 222

Query: 528 ANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSE 587
           A VVCRQLGCG AM A  NA FG G+G I+LD+V C G E  L +C   GW  HNCGH E
Sbjct: 223 AAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHE 282

Query: 588 DAGVICSG---------PES--------------------------------------SL 600
           DAG +C+G         P S                                      S 
Sbjct: 283 DAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSG 342

Query: 601 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660
            LRLV G   C+GRVEVL+ G WGTVCDD WD  DA V CR+ GCG A  A G   FG G
Sbjct: 343 RLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYG 402

Query: 661 SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
            GP++LD+V C+G E+ L  C + GW  HNCGHHEDAG +C+  +          S  T 
Sbjct: 403 RGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTR 462

Query: 721 PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
            P+    +    LRLVNG+ RC+GRVE+     WGTVCDD+WD   A V+CRQLGCG A 
Sbjct: 463 VPTPRPRDGH--LRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQAL 520

Query: 781 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVS 835
           +APG A FG G GPI+LD+V+C G ES L  C H  W +HNC H EDA V+C  S
Sbjct: 521 AAPGEAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLCQPS 575



 Score =  389 bits (998), Expect = e-107
 Identities = 206/420 (49%), Positives = 245/420 (58%), Gaps = 45/420 (10%)

Query: 1352 ASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1411
            AS  QPTP P                  LRLV G  RC+GR+EV++ GSWG+VCDD WD 
Sbjct: 45   ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89

Query: 1412 NDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1471
             DANVVCRQLGCG A   P    FGQG GPI+LD+V C G E+ L  C   GW  HNC H
Sbjct: 90   VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149

Query: 1472 HEDAGVICSASQSQPTPSPDT-WPTSRA---STAGSESTLALRLVNGGDRCRGRVEVLYQ 1527
            +ED  V+C   +  PT  P     TSRA   +    +S  ++RLV G + C+GRVE+L+ 
Sbjct: 150  YEDVAVLCD--EFLPTQPPTRKMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHS 207

Query: 1528 GSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWS 1587
            G WGTVCDD W   DA VVCRQLGCG AM+A  NA FG G+G I+LD+V C G E  L +
Sbjct: 208  GLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAA 267

Query: 1588 CPHNGWLSHNCGHHEDAGVICSA-------AQSQSTPRPDTWLTTNLPALTVGSESSLA- 1639
            C   GW  HNCGHHEDAG +C+        A   S  R D    T+  A  VG + S   
Sbjct: 268  CQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRET 327

Query: 1640 ----------------LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 1683
                            LRLV G   CRGRVEVL+ G WGTVCDD WD  DA V CR+ GC
Sbjct: 328  ALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGC 387

Query: 1684 GWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1743
            G A+ A G   FG G GP++LD+V C+G E+ L  C H GW  HNCGHHEDAG +C+  +
Sbjct: 388  GPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPE 447



 Score =  271 bits (693), Expect = 6e-72
 Identities = 141/289 (48%), Positives = 170/289 (58%), Gaps = 26/289 (8%)

Query: 1481 ASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDT 1540
            AS  QPTP P                  LRLV G  RCRGR+EV++ GSWG+VCDD WD 
Sbjct: 45   ASALQPTPLPFQ---------------ELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDV 89

Query: 1541 NDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1600
             DANVVCRQLGCG A+  P    FGQG GPI+LD+V C G E+ L  C   GW  HNC H
Sbjct: 90   VDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFH 149

Query: 1601 HEDAGVICSAAQSQSTPRPDTWLTTNLPALTV-GSESSLALRLVNGGDRCRGRVEVLYRG 1659
            +ED  V+C        P     LT+  P  T+   +S  ++RLV G + C+GRVE+L+ G
Sbjct: 150  YEDVAVLCDEFLPTQPPTRKM-LTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG 208

Query: 1660 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSC 1719
             WGTVCDD W   DA VVCRQLGCG AM+A  NA FG G+G I+LD+V C G E  L +C
Sbjct: 209  LWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHCEGGEPRLAAC 268

Query: 1720 PHKGWLTHNCGHHEDAGVIC--------SATQINSTTTDW-WHPTTTTT 1759
               GW  HNCGHHEDAG +C        +A   ++T  DW W    + T
Sbjct: 269  QSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSAT 317



 Score =  132 bits (332), Expect = 4e-30
 Identities = 60/109 (55%), Positives = 74/109 (67%), Gaps = 3/109 (2%)

Query: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938
            S+ ++RLV       LC GRVEI H G WGTVCDD W + +A VVCRQLGCG A++A  N
Sbjct: 185  SEGSVRLVG---GANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTN 241

Query: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1987
            A+FG G+G I LD+V C G E  L  C++ GW  HNC H EDAG +C+G
Sbjct: 242  AFFGYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAG 290



 Score =  129 bits (325), Expect = 3e-29
 Identities = 60/108 (55%), Positives = 75/108 (69%), Gaps = 3/108 (2%)

Query: 1878 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1937
            P D  LRLVN       C GRVE+Y G  WGTVCDD+W ++ A V+CRQLGCG+A++A G
Sbjct: 468  PRDGHLRLVN---GAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPG 524

Query: 1938 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
             A+FG G GPI LD+V+C G ES L  C +  W +HNC+H EDA V+C
Sbjct: 525  EAHFGPGRGPILLDNVKCRGEESALLLCSHIRWDAHNCDHSEDASVLC 572



 Score =  126 bits (317), Expect = 2e-28
 Identities = 52/95 (54%), Positives = 64/95 (67%)

Query: 1893 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDD 1952
            G C GRVE+ H G WGTVCDD W   +A V CR+ GCG A+ A G  +FG G GP+ LD+
Sbjct: 351  GPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDN 410

Query: 1953 VECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1987
            V C+GTE+ L  C + GW  HNC H EDAG +C+G
Sbjct: 411  VGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAG 445



 Score =  121 bits (304), Expect = 7e-27
 Identities = 51/91 (56%), Positives = 63/91 (69%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
            C GR+E+ HGG+WG+VCDD W + +A VVCRQLGCG A+       FG G GPI LD+VE
Sbjct: 67   CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGRGPILLDNVE 126

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
            C G E+ L +C +RGW  HNC H ED  V+C
Sbjct: 127  CRGQEAALSECGSRGWGVHNCFHYEDVAVLC 157


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score =  491 bits (1263), Expect = e-138
 Identities = 253/562 (45%), Positives = 316/562 (56%), Gaps = 82/562 (14%)

Query: 352 ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
           A+  G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A +
Sbjct: 9   AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68

Query: 412 APGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSA------- 464
           APG A FG+G+GP+ L ++ C G E  L  C H GW +H C H EDAGV+C+        
Sbjct: 69  APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128

Query: 465 ----------------------------------------AHSWSTPSPDTLPTITLPAS 484
                                                   A    +P P    +   P  
Sbjct: 129 DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188

Query: 485 TVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAP 544
           T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A+ AP
Sbjct: 189 TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248

Query: 545 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRL 604
           G ARFG G+GP+ +DDV C G E  L  CP + W   NC HSEDAG++C+GP  +  LRL
Sbjct: 249 GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGP--APRLRL 306

Query: 605 VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPI 664
            +G   C GR+EV + G WG+VCDD+WD  DA V CR+LGCG A +APG A FG+GSGPI
Sbjct: 307 ADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPI 366

Query: 665 VLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAA------------QSRSTPR- 711
           +LDD+RC G+E+ L  CP   W  H+C H EDAG +C                + STPR 
Sbjct: 367 ILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPRE 426

Query: 712 -----PDTLST-------ITLPPST------VGSES-SLTLRLVNGSDRCQGRVEVLYRG 752
                P T+++       ++ PP++       G E+ S  LRLV G  +C GR+EV +  
Sbjct: 427 AASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQ 486

Query: 753 SWGTVCDDSWDTNDANVVCRQLGCGWATSA-PGNARFGQGSGPIVLDDVRCSGHESYLWS 811
            WGTVCDDSWD  D+ VVCR+LGCG      P   RFG G+GPI LDDV C G E+ L  
Sbjct: 487 RWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSD 546

Query: 812 CPHNGWLSHNCGHHEDAGVICS 833
           CP   W  HNC H+ED GV C+
Sbjct: 547 CPAAPWGKHNCAHNEDVGVTCT 568



 Score =  482 bits (1240), Expect = e-135
 Identities = 254/577 (44%), Positives = 315/577 (54%), Gaps = 108/577 (18%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           LRL +G   C GR+E+ + G WGTVCDD WD  DA V CRQLGCG A++APG A+FG+G+
Sbjct: 20  LRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGA 79

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES------- 214
           GP+ L ++ C G+E  L  C H GW +H C H EDAGV+C A Q  +  R +S       
Sbjct: 80  GPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC-AGQRVANSRDDSTSPLDGA 138

Query: 215 -WP---VRISP------------------------------------PVPTEGSESSLAL 234
            WP   + +SP                                    P+ T G+     L
Sbjct: 139 PWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERL 198

Query: 235 RLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSG 294
           RLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A++APG A+FG G+G
Sbjct: 199 RLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAG 258

Query: 295 PIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHAST 354
           P+ +DDV C G E  L  CP + W   NC HSEDAG++C+ P  R               
Sbjct: 259 PVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPR--------------- 303

Query: 355 AGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
                   LRL +G   C GR+EV + G WG+VCDD+WD  DA V CR+LGCG A +APG
Sbjct: 304 --------LRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPG 355

Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPD 474
            A FG+GSGPI+LDD+RC G E+ L  CP   W  H+C H EDAG +C          P 
Sbjct: 356 GAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYV--PP 413

Query: 475 TLPT----------ITLPASTVGSES------------------------SLALRLVNGG 500
           T PT           + P ST+ S++                        S  LRLV G 
Sbjct: 414 TAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGP 473

Query: 501 DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA-PGNARFGQGSGPIVLD 559
            +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P   RFG G+GPI LD
Sbjct: 474 SKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLD 533

Query: 560 DVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGP 596
           DV C G E+ L  CP   W  HNC H+ED GV C+GP
Sbjct: 534 DVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGP 570



 Score =  481 bits (1237), Expect = e-135
 Identities = 274/662 (41%), Positives = 341/662 (51%), Gaps = 122/662 (18%)

Query: 481  LPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 540
            L A+ VG ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A
Sbjct: 7    LLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGA 66

Query: 541  MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL 600
            + APG A FG+G+GP+ L ++ C GNE  L  C H GW +H C H EDAGV+C+G     
Sbjct: 67   LAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQ---- 122

Query: 601  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660
              R+ N                     DDS    D        G  W             
Sbjct: 123  --RVANSR-------------------DDSTSPLD--------GAPW------------- 140

Query: 661  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
              P +L ++  S  E  +   P              AG   +A++ +S PRP    +   
Sbjct: 141  --PGLLLELSPSTEEPLVTHAP------------RPAGNPQNASRKKS-PRPKQAKSTRA 185

Query: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
            P  T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A 
Sbjct: 186  PLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGAL 245

Query: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840
            +APG ARFG G+GP+ +DDV C G E  L  CP + W   NC H EDAG++C+       
Sbjct: 246  AAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCT------G 299

Query: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900
            P+P                  LRL +G   C GR+EV + G WG+VCDD+WD  DA V C
Sbjct: 300  PAP-----------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVAC 342

Query: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960
            R+LGCG A +APG A FG+GSGPI+LDD+RC G E+ L  CP   W  H+C H EDAG +
Sbjct: 343  RELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAV 402

Query: 961  CSAAHSWSTPSPDTLPT----------ITLPASTVGSES--------------------- 989
            C          P T PT           + P ST+ S++                     
Sbjct: 403  CDGMPLGYV--PPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGP 460

Query: 990  ---SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA-PGN 1045
               S  LRLV G  +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P  
Sbjct: 461  EAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAA 520

Query: 1046 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS-PD 1104
             RFG G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+      + S P 
Sbjct: 521  GRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPF 580

Query: 1105 TW 1106
            +W
Sbjct: 581  SW 582



 Score =  474 bits (1219), Expect = e-133
 Identities = 256/599 (42%), Positives = 318/599 (53%), Gaps = 108/599 (18%)

Query: 980  LPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWA 1039
            L A+ VG ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A
Sbjct: 7    LLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGA 66

Query: 1040 MSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRP 1099
            ++APG A FG+G+GP+ L ++ C G+E  L  C H GW +H C H EDAGV+C+  +   
Sbjct: 67   LAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVAN 126

Query: 1100 TPSPDT-------WP--------------TSHAS-------------------------- 1112
            +    T       WP               +HA                           
Sbjct: 127  SRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAP 186

Query: 1113 --TAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1170
              T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A++
Sbjct: 187  LLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALA 246

Query: 1171 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTP 1230
            APG ARFG G+GP+ +DDV C G E  L  CP + W   NC H EDAG++C+       P
Sbjct: 247  APGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------P 300

Query: 1231 SPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCR 1290
            +P                  LRL +G   C GR+EV + G WG+VCDD WD  DA V CR
Sbjct: 301  AP-----------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACR 343

Query: 1291 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 1350
            +LGCG A +APG A FG+GSGPI+LDD+RC G+E+ L  CP   W  H+C H EDAG +C
Sbjct: 344  ELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVC 403

Query: 1351 S------ASQSQPTPSPDTWPTSHAS------------TAG----------------SES 1376
                      + PT S ++ P   AS            TAG                   
Sbjct: 404  DGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAG 463

Query: 1377 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA-PGNARF 1435
            S  LRLV G  +C GR+EV +   WGTVCDD WD  D+ VVCR+LGCG      P   RF
Sbjct: 464  SPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRF 523

Query: 1436 GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS-PDTW 1493
            G G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+      + S P +W
Sbjct: 524  GWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSW 582



 Score =  473 bits (1218), Expect = e-133
 Identities = 254/583 (43%), Positives = 315/583 (54%), Gaps = 105/583 (18%)

Query: 1240 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 1299
            A+  G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A +
Sbjct: 9    AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68

Query: 1300 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS----ASQS 1355
            APG A FG+G+GP+ L ++ C G+E  L  C H GW +H C H EDAGV+C+    A+  
Sbjct: 69   APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128

Query: 1356 QPTPSP---DTWP--------------TSHAS---------------------------- 1370
              + SP     WP               +HA                             
Sbjct: 129  DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188

Query: 1371 TAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAP 1430
            T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A +AP
Sbjct: 189  TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248

Query: 1431 GNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSP 1490
            G ARFG G+GP+ +DDV C G E  L  CP + W   NC H EDAG++C+       P+P
Sbjct: 249  GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------PAP 302

Query: 1491 DTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQL 1550
                              LRL +G   C GR+EV + G WG+VCDD WD  DA V CR+L
Sbjct: 303  -----------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACREL 345

Query: 1551 GCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA 1610
            GCG A++APG A FG+GSGPI+LDD+RC G+E+ L  CP   W  H+C H EDAG +C  
Sbjct: 346  GCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDG 405

Query: 1611 A------------QSQSTPR-----PDTWLTTNLPALT--------------VGSES-SL 1638
                          + STPR     P + +T+  P                  G E+ S 
Sbjct: 406  MPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSP 465

Query: 1639 ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA-PGNARFGQ 1697
             LRLV G  +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P   RFG 
Sbjct: 466  QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW 525

Query: 1698 GSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+
Sbjct: 526  GAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  469 bits (1207), Expect = e-131
 Identities = 255/597 (42%), Positives = 316/597 (52%), Gaps = 108/597 (18%)

Query: 1111 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1170
            A+  G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A++
Sbjct: 9    AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68

Query: 1171 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS----ASQS 1226
            APG A FG+G+GP+ L ++ C G+E  L  C H GW +H C H EDAGV+C+    A+  
Sbjct: 69   APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128

Query: 1227 QPTPSP---DTWP--------------TSHAS---------------------------- 1241
              + SP     WP               +HA                             
Sbjct: 129  DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188

Query: 1242 TAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAP 1301
            T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A +AP
Sbjct: 189  TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248

Query: 1302 GNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSP 1361
            G ARFG G+GP+ +DDV C G E  L  CP + W   NC H EDAG++C+       P+P
Sbjct: 249  GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------PAP 302

Query: 1362 DTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQL 1421
                              LRL +G   C GR+EV + G WG+VCDD WD  DA V CR+L
Sbjct: 303  -----------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACREL 345

Query: 1422 GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS- 1480
            GCG A +APG A FG+GSGPI+LDD+RC G+E+ L  CP   W  H+C H EDAG +C  
Sbjct: 346  GCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDG 405

Query: 1481 -----ASQSQPTPSPDTWPTSRAS------------TAGSESTLA--------------- 1508
                    + PT S ++ P   AS            TAG     A               
Sbjct: 406  MPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSP 465

Query: 1509 -LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA-PGNAQFGQ 1566
             LRLV G  +C GR+EV +   WGTVCDD WD  D+ VVCR+LGCG      P   +FG 
Sbjct: 466  QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW 525

Query: 1567 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQS-QSTPRPDTW 1622
            G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+      S   P +W
Sbjct: 526  GAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSW 582



 Score =  462 bits (1190), Expect = e-129
 Identities = 246/581 (42%), Positives = 301/581 (51%), Gaps = 130/581 (22%)

Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A++APG 
Sbjct: 13  GIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGG 72

Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346
           A FG+G+GP+ L ++ C G+E  L  C H GW  H C H EDAGV+C+  +   +    T
Sbjct: 73  AFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDST 132

Query: 347 -------WP--------------TSHAS----------------------------TAGP 357
                  WP               +HA                             T G 
Sbjct: 133 SPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGA 192

Query: 358 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNAR 417
                LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A +APG AR
Sbjct: 193 PRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGAR 252

Query: 418 FGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLP 477
           FG G+GP+ +DDV C G E  L  CP + W   NC HSEDAG++C+       P+P    
Sbjct: 253 FGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG------PAP---- 302

Query: 478 TITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 537
                           LRL +G   C GR+EV + G WG+VCDD+WD  DA V CR+LGC
Sbjct: 303 ---------------RLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGC 347

Query: 538 GWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSG-- 595
           G A+ APG A FG+GSGPI+LDD+RC GNE+ L  CP   W  H+C H EDAG +C G  
Sbjct: 348 GGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMP 407

Query: 596 -----------------------PESSLA------------------------------L 602
                                  P S++                               L
Sbjct: 408 LGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQL 467

Query: 603 RLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA-PGNARFGQGS 661
           RLV G  +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG      P   RFG G+
Sbjct: 468 RLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGA 527

Query: 662 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 702
           GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+
Sbjct: 528 GPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  363 bits (932), Expect = 1e-99
 Identities = 187/415 (45%), Positives = 233/415 (56%), Gaps = 61/415 (14%)

Query: 84  SESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQL 143
           ++ST    +  G+     LRLV+G  RC GR+E+ + G WGTVCDD WD  DA V CR+L
Sbjct: 180 AKSTRAPLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACREL 239

Query: 144 GCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSA 203
           GCG A++APG A FG G+GP+ +DDV C G E  L  CP + W   NC H EDAG++C+ 
Sbjct: 240 GCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG 299

Query: 204 AQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYW 263
             P+                          LRL +G   C GR+EV + G WG+VCDD W
Sbjct: 300 PAPR--------------------------LRLADGPHGCAGRLEVWHGGRWGSVCDDAW 333

Query: 264 DTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNC 323
           D  DA V CR+LGCG A++APG A FG+GSGPI+LDD+RC G+E+ L  CP   W  H+C
Sbjct: 334 DLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDC 393

Query: 324 GHSEDAGVICS------APQSRPTPSPDTWPTSHAS------------------------ 353
            H EDAG +C        P + PT S ++ P   AS                        
Sbjct: 394 HHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPT 453

Query: 354 ---TAGPES-SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWA 409
                GPE+ S  LRLV G  +C GR+EV +   WGTVCDDSWD  D+ VVCR+LGCG  
Sbjct: 454 VLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGP 513

Query: 410 TSA-PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
               P   RFG G+GPI LDDV C G E+ L  CP   W  HNC H+ED GV C+
Sbjct: 514 QQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCT 568



 Score =  348 bits (894), Expect = 3e-95
 Identities = 209/578 (36%), Positives = 268/578 (46%), Gaps = 105/578 (18%)

Query: 1498 ASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1557
            A+  G ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A++
Sbjct: 9    AALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALA 68

Query: 1558 APGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA------- 1610
            APG A FG+G+GP+ L ++ C G+E  L  C H GW +H C H EDAGV+C+        
Sbjct: 69   APGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSR 128

Query: 1611 ----------------------------------------AQSQSTPRPDTWLTTNLPAL 1630
                                                    A  + +PRP    +T  P L
Sbjct: 129  DDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLL 188

Query: 1631 TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 1690
            T G+     LRLV+G  RC GR+EV + G WGTVCDD WD  DA V CR+LGCG A++AP
Sbjct: 189  TTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAP 248

Query: 1691 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSAT-------- 1742
            G ARFG G+GP+ +DDV C G E  L  CP   W   NC H EDAG++C+          
Sbjct: 249  GGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLAD 308

Query: 1743 ---------------QINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYP 1787
                           +  S   D W       A     CGG L    G F          
Sbjct: 309  GPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIIL 368

Query: 1788 NNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF--DYVEIFDGSLNSSLLLGKICNDTR 1845
            ++ +C        G    L F   +    H+C    D   + DG     + LG +     
Sbjct: 369  DDLRC-------RGNETALRFCPARPWGQHDCHHREDAGAVCDG-----MPLGYVPPTAP 416

Query: 1846 QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-------------LRLVNLNSSY 1892
                +S  R                 A  +  P+  T             LRLV   S  
Sbjct: 417  TDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSK- 475

Query: 1893 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG---RAVSALGNAYFGSGSGPIT 1949
              C+GR+E++H   WGTVCDDSW ++++ VVCR+LGCG   +   A G   FG G+GPI 
Sbjct: 476  --CSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGR--FGWGAGPIW 531

Query: 1950 LDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1987
            LDDV C GTE++L  C    W  HNC H ED GV C+G
Sbjct: 532  LDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTG 569



 Score =  143 bits (361), Expect = 2e-33
 Identities = 64/128 (50%), Positives = 83/128 (64%)

Query: 1627 LPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 1686
            L A  VG ++   LRL +G   C GR+EV + G WGTVCDD WD  DA V CRQLGCG A
Sbjct: 7    LLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGA 66

Query: 1687 MSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINS 1746
            ++APG A FG+G+GP+ L ++ C GNE  L  C H+GW  H C H EDAGV+C+  ++ +
Sbjct: 67   LAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVAN 126

Query: 1747 TTTDWWHP 1754
            +  D   P
Sbjct: 127  SRDDSTSP 134



 Score =  139 bits (350), Expect = 3e-32
 Identities = 66/154 (42%), Positives = 81/154 (52%), Gaps = 1/154 (0%)

Query: 1354 QSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTND 1413
            +  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD WD  D
Sbjct: 746  EGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRD 805

Query: 1414 ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1473
            A V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H E
Sbjct: 806  ATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEE 865

Query: 1474 DAGVICSASQSQPTPSPDTW-PTSRASTAGSEST 1506
            D G+ C+         P TW PTSR   A   +T
Sbjct: 866  DVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTT 899



 Score =  137 bits (344), Expect = 2e-31
 Identities = 70/167 (41%), Positives = 91/167 (54%), Gaps = 4/167 (2%)

Query: 51  PSESTLESTVAEGSPISLESTLESTVAEGSL-IPSESTLESTVAEGSDSGL-ALRLVNGD 108
           P E T EST+      SLE + E  + EGS   P +     +V+   +SGL  +RL +G 
Sbjct: 721 PQEMTSESTIKSIPQASLEPSAE--IPEGSPESPKDPAPSPSVSTTGESGLFRVRLADGP 778

Query: 109 GRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDD 168
            RC GR+E+ + G WGTVCDD+WD  DA V C +LGCG      G   +G G+GPI LDD
Sbjct: 779 NRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTGPIWLDD 838

Query: 169 VRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESW 215
           + C G E+ L  CP   W  HNC H ED G+ C+         P +W
Sbjct: 839 MGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPPWTW 885



 Score =  136 bits (343), Expect = 2e-31
 Identities = 63/155 (40%), Positives = 81/155 (52%)

Query: 1483 QSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTND 1542
            +  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD WD  D
Sbjct: 746  EGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRD 805

Query: 1543 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1602
            A V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H E
Sbjct: 806  ATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEE 865

Query: 1603 DAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESS 1637
            D G+ C+         P TW  T+   L  G+ ++
Sbjct: 866  DVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTA 900



 Score =  136 bits (342), Expect = 3e-31
 Identities = 63/143 (44%), Positives = 85/143 (59%), Gaps = 7/143 (4%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
            CAGR+E++HGG WGTVCDD W +++A V CRQLGCG A++A G A+FG G+GP+ L ++ 
Sbjct: 29   CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAGPVWLSELA 88

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQ 2014
            C G E  L  C +RGW +H C+H EDAGV+C+G  ++      + T P       G L +
Sbjct: 89   CRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRD--DSTSPLDGAPWPGLLLE 146

Query: 2015 PSGDFSSPFY-----PGNYPNNA 2032
             S     P       P   P NA
Sbjct: 147  LSPSTEEPLVTHAPRPAGNPQNA 169



 Score =  136 bits (342), Expect = 3e-31
 Identities = 64/149 (42%), Positives = 78/149 (52%), Gaps = 1/149 (0%)

Query: 1225 QSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTND 1284
            +  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD WD  D
Sbjct: 746  EGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRD 805

Query: 1285 ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1344
            A V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H E
Sbjct: 806  ATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEE 865

Query: 1345 DAGVICSASQSQPTPSPDTW-PTSHASTA 1372
            D G+ C+         P TW PTS    A
Sbjct: 866  DVGLTCTGYTDYDDYPPWTWDPTSREDLA 894



 Score =  135 bits (341), Expect = 4e-31
 Identities = 56/101 (55%), Positives = 73/101 (72%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVE 1954
            CAGR+E++HGG WG+VCDD+W +++A V CR+LGCG A++A G A+FG GSGPI LDD+ 
Sbjct: 313  CAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLR 372

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAP 1995
            C G E+ L  C  R W  H+C+HREDAG +C G  L    P
Sbjct: 373  CRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPP 413



 Score =  135 bits (341), Expect = 4e-31
 Identities = 64/149 (42%), Positives = 78/149 (52%), Gaps = 1/149 (0%)

Query: 1096 QSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTND 1155
            +  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD WD  D
Sbjct: 746  EGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRD 805

Query: 1156 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHE 1215
            A V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H E
Sbjct: 806  ATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEE 865

Query: 1216 DAGVICSASQSQPTPSPDTW-PTSHASTA 1243
            D G+ C+         P TW PTS    A
Sbjct: 866  DVGLTCTGYTDYDDYPPWTWDPTSREDLA 894



 Score =  134 bits (337), Expect = 1e-30
 Identities = 72/187 (38%), Positives = 91/187 (48%), Gaps = 20/187 (10%)

Query: 336 PQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395
           P+  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD+WD  
Sbjct: 745 PEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLR 804

Query: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455
           DA V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H 
Sbjct: 805 DATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHE 864

Query: 456 EDAGVICSA--------AHSWSTPSPDTL---------PTITLPASTV---GSESSLALR 495
           ED G+ C+           +W   S + L         P  TLP  T    GS S    R
Sbjct: 865 EDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIRR 924

Query: 496 LVNGGDR 502
           L + G +
Sbjct: 925 LPDTGSK 931



 Score =  133 bits (334), Expect = 2e-30
 Identities = 63/137 (45%), Positives = 75/137 (54%), Gaps = 1/137 (0%)

Query: 220 SPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
           SP V T G      +RL +G +RC GR+EV + G WGTVCDD WD  DA V C +LGCG 
Sbjct: 758 SPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGK 817

Query: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
                G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H ED G+ C+     
Sbjct: 818 VRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDY 877

Query: 340 PTPSPDTW-PTSHASTA 355
               P TW PTS    A
Sbjct: 878 DDYPPWTWDPTSREDLA 894



 Score =  132 bits (333), Expect = 3e-30
 Identities = 63/147 (42%), Positives = 78/147 (53%), Gaps = 1/147 (0%)

Query: 969  TPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDAN 1028
            +P     P  +   ST G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA 
Sbjct: 748  SPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807

Query: 1029 VVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDA 1088
            V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H ED 
Sbjct: 808  VACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDV 867

Query: 1089 GVICSASQSRPTPSPDTW-PTSHASTA 1114
            G+ C+         P TW PTS    A
Sbjct: 868  GLTCTGYTDYDDYPPWTWDPTSREDLA 894



 Score =  132 bits (332), Expect = 4e-30
 Identities = 71/188 (37%), Positives = 91/188 (48%), Gaps = 20/188 (10%)

Query: 834  VSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 893
            + +  P    D  P+   ST G      +RL +G +RC GR+EV + G WGTVCDD+WD 
Sbjct: 744  IPEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDL 803

Query: 894  SDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQH 953
             DA V C +LGCG      G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H
Sbjct: 804  RDATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDH 863

Query: 954  SEDAGVICSA--------AHSWSTPSPDTL---------PTITLPASTV---GSESSLAL 993
             ED G+ C+           +W   S + L         P  TLP  T    GS S    
Sbjct: 864  EEDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIR 923

Query: 994  RLVNGGDR 1001
            RL + G +
Sbjct: 924  RLPDTGSK 931



 Score =  131 bits (330), Expect = 7e-30
 Identities = 64/135 (47%), Positives = 83/135 (61%), Gaps = 10/135 (7%)

Query: 1878 PSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALG 1937
            P    LRLV   S    CAGR+E++HGG WGTVCDD W +++A V CR+LGCG A++A G
Sbjct: 193  PRQERLRLV---SGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPG 249

Query: 1938 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL 1997
             A FG G+GP+ +DDV C G E  L  C    W   NC+H EDAG++C+G     PAP L
Sbjct: 250  GARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG-----PAPRL 304

Query: 1998 NITRPNTDYSCGGFL 2012
             +   +  + C G L
Sbjct: 305  RLA--DGPHGCAGRL 317



 Score =  131 bits (329), Expect = 9e-30
 Identities = 61/133 (45%), Positives = 74/133 (55%), Gaps = 1/133 (0%)

Query: 723 STVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 782
           ST G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA V C +LGCG     
Sbjct: 762 STTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPR 821

Query: 783 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPS 842
            G   +G G+GPI LDD+ C G E+ L  CP   W  HNC H ED G+ C+         
Sbjct: 822 VGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYP 881

Query: 843 PDTW-PTSHASTA 854
           P TW PTS    A
Sbjct: 882 PWTWDPTSREDLA 894



 Score =  129 bits (325), Expect = 3e-29
 Identities = 57/126 (45%), Positives = 73/126 (57%)

Query: 470 TPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDAN 529
           +P     P  +   ST G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA 
Sbjct: 748 SPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDAT 807

Query: 530 VVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDA 589
           V C +LGCG      G   +G G+GPI LDD+ C G+E+ L  CP   W  HNC H ED 
Sbjct: 808 VACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDV 867

Query: 590 GVICSG 595
           G+ C+G
Sbjct: 868 GLTCTG 873



 Score =  128 bits (322), Expect = 6e-29
 Identities = 61/138 (44%), Positives = 76/138 (55%), Gaps = 8/138 (5%)

Query: 1631 TVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 1690
            T G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA V C +LGCG      
Sbjct: 763  TTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRV 822

Query: 1691 GNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTD 1750
            G   +G G+GPI LDD+ C G+E+ L  CP   W  HNC H ED G+ C+          
Sbjct: 823  GKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPP 882

Query: 1751 W-WHPTT-------TTTA 1760
            W W PT+       TTTA
Sbjct: 883  WTWDPTSREDLAKGTTTA 900



 Score =  124 bits (311), Expect = 1e-27
 Identities = 53/112 (47%), Positives = 68/112 (60%)

Query: 591 VICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 650
           V  +G      +RL +G +RC GR+EV + G WGTVCDD+WD  DA V C +LGCG    
Sbjct: 761 VSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRP 820

Query: 651 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 702
             G   +G G+GPI LDD+ C G E+ L  CP+  W  HNC H ED G+ C+
Sbjct: 821 RVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCT 872



 Score =  122 bits (307), Expect = 3e-27
 Identities = 50/112 (44%), Positives = 73/112 (65%)

Query: 1876 SFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1935
            S   ++ L  V L      CAGR+E++H G WGTVCDD+W +++A V C +LGCG+    
Sbjct: 762  STTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPR 821

Query: 1936 LGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1987
            +G  ++G G+GPI LDD+ C G+E++L  C +  W  HNC+H ED G+ C+G
Sbjct: 822  VGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTG 873


>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 343

 Score =  474 bits (1219), Expect = e-133
 Identities = 220/250 (88%), Positives = 223/250 (89%), Gaps = 22/250 (8%)

Query: 484 STVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 543
           S VGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 544 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSG-------- 595
           PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSG        
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 596 --------------PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 641
                         PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR
Sbjct: 128 PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 642 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 701
           QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC
Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 702 SAAQSRSTPR 711
           S + + + PR
Sbjct: 248 SGSWAVAGPR 257



 Score =  474 bits (1219), Expect = e-133
 Identities = 218/249 (87%), Positives = 224/249 (89%), Gaps = 1/249 (0%)

Query: 983  STVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 1042
            S VGSESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVCRQLGCGWAM A
Sbjct: 8    SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 1043 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPS 1102
            PGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGHSEDAGVICS    R    
Sbjct: 68   PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 1103 PDTWPTSH-ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCR 1161
            P +WP+    S  G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCR
Sbjct: 128  PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 1162 QLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 1221
            QLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHEDAGVIC
Sbjct: 188  QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 1222 SASQSQPTP 1230
            S S +   P
Sbjct: 248  SGSWAVAGP 256



 Score =  470 bits (1210), Expect = e-132
 Identities = 216/249 (86%), Positives = 222/249 (89%), Gaps = 1/249 (0%)

Query: 1112 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1171
            S  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWAM A
Sbjct: 8    SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 1172 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1231
            PGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS    +    
Sbjct: 68   PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 1232 PDTWPTSH-ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCR 1290
            P +WP+    S  G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCR
Sbjct: 128  PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 1291 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 1350
            QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHEDAGVIC
Sbjct: 188  QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 1351 SASQSQPTP 1359
            S S +   P
Sbjct: 248  SGSWAVAGP 256



 Score =  468 bits (1205), Expect = e-131
 Identities = 225/294 (76%), Positives = 236/294 (80%), Gaps = 25/294 (8%)

Query: 1241 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1300
            S  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWA  A
Sbjct: 8    SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 1301 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1360
            PGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS    +    
Sbjct: 68   PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 1361 PDTWPTSH-ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCR 1419
            P +WP+    S  G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCR
Sbjct: 128  PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 1420 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 1479
            QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHEDAGVIC
Sbjct: 188  QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 1480 SASQSQPTP----------------------SPDTWPTSRA--STAGSESTLAL 1509
            S S +   P                      + DT PT  A  + AGS +T+A+
Sbjct: 248  SGSWAVAGPRRPQEMPGLARAQDPLFWMMCAAQDTSPTCGAAPTMAGSPTTVAI 301



 Score =  464 bits (1195), Expect = e-130
 Identities = 215/251 (85%), Positives = 222/251 (88%), Gaps = 3/251 (1%)

Query: 723 STVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 782
           S VGSESSL LRLVNG DRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA  A
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 783 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPS 842
           PGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS    R    
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 843 PDTWPTSH-ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCR 901
           P +WP+    S  GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT+DANVVCR
Sbjct: 128 PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 902 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 961
           QLGCGWATSAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNC H EDAGVIC
Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 962 SAAHSWSTPSP 972
           S   SW+   P
Sbjct: 248 SG--SWAVAGP 256



 Score =  464 bits (1193), Expect = e-130
 Identities = 213/248 (85%), Positives = 223/248 (89%), Gaps = 3/248 (1%)

Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           GSESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWAM APGN
Sbjct: 11  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 70

Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346
           A+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWL+HNCGHSEDAGVICS    R    P +
Sbjct: 71  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRS 130

Query: 347 WPTSH-ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLG 405
           WP+    S  GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT+DANVVCRQLG
Sbjct: 131 WPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 190

Query: 406 CGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA 465
           CGWATSAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNC H EDAGVICS  
Sbjct: 191 CGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSG- 249

Query: 466 HSWSTPSP 473
            SW+   P
Sbjct: 250 -SWAVAGP 256



 Score =  461 bits (1186), Expect = e-129
 Identities = 210/250 (84%), Positives = 222/250 (88%), Gaps = 1/250 (0%)

Query: 1370 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1429
            S  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD WDTNDANVVCRQLGCGWA  A
Sbjct: 8    SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 1430 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1489
            PGNARFGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS    +    
Sbjct: 68   PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 1490 PDTWPTS-RASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCR 1548
            P +WP+    S  G ES+LALRLVNGGDRC+GRVEVLY+GSWGTVCDD WDTNDANVVCR
Sbjct: 128  PRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 1549 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 1608
            QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHHEDAGVIC
Sbjct: 188  QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 1609 SAAQSQSTPR 1618
            S + + + PR
Sbjct: 248  SGSWAVAGPR 257



 Score =  459 bits (1181), Expect = e-128
 Identities = 215/250 (86%), Positives = 223/250 (89%), Gaps = 3/250 (1%)

Query: 588 DAGVICS--GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 645
           D G + S  G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC
Sbjct: 2   DEGFLFSPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGC 61

Query: 646 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQ 705
           GWA  APGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNCGH EDAGVICS   
Sbjct: 62  GWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGP 121

Query: 706 SRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTN 765
            R+  RP +  +  L  S +G ESSL LRLVNG DRCQGRVEVLYRGSWGTVCDDSWDTN
Sbjct: 122 PRTPIRPRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTN 180

Query: 766 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHH 825
           DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGHH
Sbjct: 181 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHH 240

Query: 826 EDAGVICSVS 835
           EDAGVICS S
Sbjct: 241 EDAGVICSGS 250



 Score =  456 bits (1173), Expect = e-127
 Identities = 206/241 (85%), Positives = 218/241 (90%), Gaps = 4/241 (1%)

Query: 95  GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154
           GS+S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM APGN
Sbjct: 11  GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 70

Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPES 214
           A FGQGSGPI LDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS   P++ +RP S
Sbjct: 71  ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRS 130

Query: 215 WPVR-ISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCR 273
           WP R +  P+   G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDD WDTNDANVVCR
Sbjct: 131 WPSRFLCSPI---GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCR 187

Query: 274 QLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVIC 333
           QLGCGWA SAPGNA+FGQGSGPIVLDDVRCSGHESYLWSCP+NGWL+HNCGH EDAGVIC
Sbjct: 188 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVIC 247

Query: 334 S 334
           S
Sbjct: 248 S 248



 Score =  455 bits (1170), Expect = e-127
 Identities = 223/295 (75%), Positives = 236/295 (80%), Gaps = 25/295 (8%)

Query: 852  STAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 911
            S  G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT+DANVVCRQLGCGWA  A
Sbjct: 8    SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 912  PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 971
            PGNARFGQGSGPIVLDDVRCSG ESYLWSCPHNGWLSHNC HSEDAGVICS     +   
Sbjct: 68   PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 972  PDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVC 1031
            P + P+  L  S +G ESSLALRLVNGGDRCQGRVEVLY+GSWGTVCDDSWDTNDANVVC
Sbjct: 128  PRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 186

Query: 1032 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVI 1091
            RQLGCGWA SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCP+NGWLSHNCGH EDAGVI
Sbjct: 187  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 246

Query: 1092 CSASQS-----RPTPSP-----------------DTWPTSHA--STAGSESSLAL 1122
            CS S +     RP   P                 DT PT  A  + AGS +++A+
Sbjct: 247  CSGSWAVAGPRRPQEMPGLARAQDPLFWMMCAAQDTSPTCGAAPTMAGSPTTVAI 301



 Score =  454 bits (1169), Expect = e-127
 Identities = 206/244 (84%), Positives = 221/244 (90%), Gaps = 1/244 (0%)

Query: 1499 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1558
            S  GSES+LALRLVNGGDRC+GRVEVLY+GSWGTVCDD WDTNDANVVCRQLGCGWAM A
Sbjct: 8    SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 1559 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1618
            PGNA+FGQGSGPIVLDDVRCSG+ESYLWSCPHNGWLSHNCGH EDAGVICS    ++  R
Sbjct: 68   PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 1619 PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVC 1678
            P +W +  L    +G ESSLALRLVNGGDRC+GRVEVLYRGSWGTVCDDSWDTNDANVVC
Sbjct: 128  PRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 186

Query: 1679 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVI 1738
            RQLGCGWA SAPGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+ GWL+HNCGHHEDAGVI
Sbjct: 187  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 246

Query: 1739 CSAT 1742
            CS +
Sbjct: 247  CSGS 250



 Score =  452 bits (1162), Expect = e-126
 Identities = 210/243 (86%), Positives = 217/243 (89%), Gaps = 1/243 (0%)

Query: 353 STAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSA 412
           S  G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT+DANVVCRQLGCGWA  A
Sbjct: 8   SPVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLA 67

Query: 413 PGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPS 472
           PGNARFGQGSGPIVLDDVRCSG ESYLWSCPHNGWLSHNC HSEDAGVICS     +   
Sbjct: 68  PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIR 127

Query: 473 PDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 532
           P + P+  L  S +G ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC
Sbjct: 128 PRSWPSRFL-CSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVC 186

Query: 533 RQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVI 592
           RQLGCGWA  APGNARFGQGSGPIVLDDVRCSG+ESYLWSCP+NGWLSHNCGH EDAGVI
Sbjct: 187 RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVI 246

Query: 593 CSG 595
           CSG
Sbjct: 247 CSG 249



 Score =  220 bits (561), Expect = 1e-56
 Identities = 100/123 (81%), Positives = 105/123 (85%), Gaps = 1/123 (0%)

Query: 95  GSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 154
           G +S LALRLVNG  RCQGRVE+LYRGSWGTVCDDSWDTNDANVVCRQLGCGWA SAPGN
Sbjct: 141 GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 200

Query: 155 AWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAA-QPQSTLRPE 213
           A FGQGSGPI LDDVRCSGHESYLWSCP+NGWLSHNCGH EDAGVICS +       RP+
Sbjct: 201 ARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGSWAVAGPRRPQ 260

Query: 214 SWP 216
             P
Sbjct: 261 EMP 263



 Score =  156 bits (394), Expect = 3e-37
 Identities = 73/110 (66%), Positives = 78/110 (70%), Gaps = 3/110 (2%)

Query: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGN 1938
            S   LRLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLGCG A SA GN
Sbjct: 144  SSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 200

Query: 1939 AYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1988
            A FG GSGPI LDDV CSG ES LW C N GW SHNC H EDAGVICSG+
Sbjct: 201  ARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSGS 250



 Score =  155 bits (393), Expect = 3e-37
 Identities = 85/153 (55%), Positives = 92/153 (60%), Gaps = 11/153 (7%)

Query: 1869 GFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLG 1928
            GFL       S   LRLVN       C GRVE+ + G+WGTVCDDSW   +A VVCRQLG
Sbjct: 4    GFLFSPVGSESSLALRLVNGGDR---CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLG 60

Query: 1929 CGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGN 1988
            CG A+ A GNA FG GSGPI LDDV CSG ES LW C + GW SHNC H EDAGVICSG 
Sbjct: 61   CGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGG 120

Query: 1989 HLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSS 2021
               TP       RP +  S   FL  P G  SS
Sbjct: 121  PPRTP------IRPRSWPS--RFLCSPIGPESS 145


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score =  371 bits (952), Expect = e-102
 Identities = 200/473 (42%), Positives = 249/473 (52%), Gaps = 44/473 (9%)

Query: 362 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 421
           ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 422 SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 481
             PI   +VRC G E  +  C  + W    C     A V CS +H          PT  +
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279

Query: 482 PASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541
                       +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 280 ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327

Query: 542 LAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLA 601
            A   A FG+GSGP++LD+VRC+GNE  +  CP + W  HNCGH EDAGV C+ P +   
Sbjct: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT-PLTDGV 386

Query: 602 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661
           +RL  G    +GR+EV YRG WGTVCDD W   +  VVCRQLG  +   A  N  F + +
Sbjct: 387 IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQASAN-HFEEST 445

Query: 662 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLP 721
           GPI LDDV CSG E+    C    W  H+C H ED  + C                    
Sbjct: 446 GPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY------------------- 486

Query: 722 PSTVGSESSL--TLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 779
           P   G   SL   +RL++G ++ +GRVEV   G WGT+CDD W   DA V+CRQLG    
Sbjct: 487 PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGP 546

Query: 780 TSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVIC 832
             A   A FG+G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 547 ARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599



 Score =  359 bits (921), Expect = 2e-98
 Identities = 197/495 (39%), Positives = 248/495 (50%), Gaps = 67/495 (13%)

Query: 601  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG 660
            ++RL  G +  +G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 661  SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278

Query: 721  PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
                        +RL  GS   +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327

Query: 781  SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPT 840
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+       
Sbjct: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380

Query: 841  PSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVC 900
                           P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VVC
Sbjct: 381  ---------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVC 425

Query: 901  RQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVI 960
            RQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + 
Sbjct: 426  RQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIA 484

Query: 961  C---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTV 1017
            C      H  S   P                    +RL++G ++ +GRVEV   G WGT+
Sbjct: 485  CYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGTI 524

Query: 1018 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGW 1077
            CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C     
Sbjct: 525  CDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDI 584

Query: 1078 LSHNCGHSEDAGVIC 1092
              HNC HSEDAGVIC
Sbjct: 585  GRHNCRHSEDAGVIC 599



 Score =  358 bits (920), Expect = 3e-98
 Identities = 199/490 (40%), Positives = 248/490 (50%), Gaps = 59/490 (12%)

Query: 861  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920
            ++RL  G +  +G VEV   G WGTVC   WD SDA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 921  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980
              PI   +VRC G E  +  C  + W    C     A V CS +H          PT  +
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHG---------PTFPI 279

Query: 981  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040
                        +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 280  ------------IRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327

Query: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       T
Sbjct: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------T 380

Query: 1101 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 1160
            P  D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VVC
Sbjct: 381  PLTDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVC 425

Query: 1161 RQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVI 1220
            RQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + 
Sbjct: 426  RQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIA 484

Query: 1221 CSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYW 1280
            C                 H  + G      +RL++G ++ +GRVEV   G WGT+CDD W
Sbjct: 485  CYPGGE-----------GHRLSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529

Query: 1281 DTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1340
               DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       HNC
Sbjct: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589

Query: 1341 GHHEDAGVIC 1350
             H EDAGVIC
Sbjct: 590  RHSEDAGVIC 599



 Score =  356 bits (913), Expect = 2e-97
 Identities = 197/496 (39%), Positives = 246/496 (49%), Gaps = 68/496 (13%)

Query: 101 ALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
           ++RL  G    +G VE+   G WGTVC   WD +DA+V+C QL  G    A    + G G
Sbjct: 169 SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRIS 220
             PI   +VRC G E  +  C  + W    C     A V CS +                
Sbjct: 229 LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSH--------------G 274

Query: 221 PPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWA 280
           P  P         +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG    
Sbjct: 275 PTFP--------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGI 326

Query: 281 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRP 340
             A   A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C+      
Sbjct: 327 AKAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------ 380

Query: 341 TPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVV 400
                           P +   +RL  G    +GR+EV YRG WGTVCDD W   +  VV
Sbjct: 381 ----------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVV 424

Query: 401 CRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGV 460
           CRQLG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  +
Sbjct: 425 CRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSI 483

Query: 461 IC---SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517
            C      H  S   P                    +RL++G ++ +GRVEV   G WGT
Sbjct: 484 ACYPGGEGHRLSLGFP--------------------VRLMDGENKKEGRVEVFINGQWGT 523

Query: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577
           +CDD W   DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C    
Sbjct: 524 ICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQD 583

Query: 578 WLSHNCGHSEDAGVIC 593
              HNC HSEDAGVIC
Sbjct: 584 IGRHNCRHSEDAGVIC 599



 Score =  355 bits (911), Expect = 3e-97
 Identities = 197/490 (40%), Positives = 246/490 (50%), Gaps = 59/490 (12%)

Query: 1250 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1309
            ++RL  G +  +G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 1310 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1369
              PI   +VRC G E  +  C  + W    C     A V CS S     P          
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278

Query: 1370 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1429
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329

Query: 1430 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1489
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382

Query: 1490 PDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1549
             D                 +RL  G     GR+EV Y+G WGTVCDD W   +  VVCRQ
Sbjct: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427

Query: 1550 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACY 486

Query: 1610 AAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSW 1669
                                L++G      +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 487  PGGEGHR-------------LSLG----FPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529

Query: 1670 DTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1729
               DA V+CRQLG      A   A FG+G GPI +D+V+C+GNE  L  C  +    HNC
Sbjct: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589

Query: 1730 GHHEDAGVIC 1739
             H EDAGVIC
Sbjct: 590  RHSEDAGVIC 599



 Score =  354 bits (908), Expect = 7e-97
 Identities = 198/490 (40%), Positives = 247/490 (50%), Gaps = 61/490 (12%)

Query: 1121 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1180
            ++RL  G +  +G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 1181 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1240
              PI   +VRC G E  +  C  + W    C     A V CS S     P          
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278

Query: 1241 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1300
                      +RL  G    +GRVE+ + G WGTVCDD WD  DA V+CRQLG      A
Sbjct: 279  ---------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKA 329

Query: 1301 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1360
               A FG+GSGP++LD+VRC+G+E  +  CP + W  HNCGH EDAGV C       TP 
Sbjct: 330  WHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------TPL 382

Query: 1361 PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1420
             D                 +RL  G    +GR+EV YRG WGTVCDD W   +  VVCRQ
Sbjct: 383  TDG---------------VIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCRQ 427

Query: 1421 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
            LG  +   A  N  F + +GPI LDDV CSG E+    C    W  H+C H ED  + C 
Sbjct: 428  LGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC- 485

Query: 1481 ASQSQPTPSPDTWPTSRASTAGSESTLA--LRLVNGGDRCRGRVEVLYQGSWGTVCDDYW 1538
                        +P       G   +L   +RL++G ++  GRVEV   G WGT+CDD W
Sbjct: 486  ------------YPGGE----GHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGW 529

Query: 1539 DTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1598
               DA V+CRQLG      A   A FG+G GPI +D+V+C+G+E  L  C       HNC
Sbjct: 530  TDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNC 589

Query: 1599 GHHEDAGVIC 1608
             H EDAGVIC
Sbjct: 590  RHSEDAGVIC 599



 Score =  261 bits (666), Expect = 8e-69
 Identities = 172/488 (35%), Positives = 217/488 (44%), Gaps = 67/488 (13%)

Query: 1508 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1567
            ++RL  G +   G VEV   G WGTVC  +WD +DA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 1568 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1627
              PI   +VRC G E  +  C  + W    C     A V CS +   + P          
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP---------- 278

Query: 1628 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1687
                        +RL  G     GRVE+ + G WGTVCDD WD  DA V+CRQLG     
Sbjct: 279  -----------IIRLAGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIA 327

Query: 1688 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINST 1747
             A   A FG+GSGP++LD+VRC+GNE  +  CP   W  HNCGH EDAGV C+       
Sbjct: 328  KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCT------- 380

Query: 1748 TTDWWHPTTTTTAR----PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYR 1803
                  P T    R      S+ G    Y  G + +     +   N   V          
Sbjct: 381  ------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR-------- 426

Query: 1804 INLGFS-NLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSD 1862
              LGF    +  A+H         F+ S     L    C+     F     R     R D
Sbjct: 427  -QLGFKYGKQASANH---------FEESTGPIWLDDVSCSGKETRFLQCSRRQ--WGRHD 474

Query: 1863 ISFQNTGFLAWYNSFPSDATLRL-----VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTI 1917
             S +    +A Y   P     RL     V L        GRVE++  G WGT+CDD WT 
Sbjct: 475  CSHREDVSIACY---PGGEGHRLSLGFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTD 531

Query: 1918 QEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNH 1977
            ++A V+CRQLG      A   AYFG G GPI +D+V+C+G E +L  C  +    HNC H
Sbjct: 532  KDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRH 591

Query: 1978 REDAGVIC 1985
             EDAGVIC
Sbjct: 592  SEDAGVIC 599



 Score =  149 bits (375), Expect = 4e-35
 Identities = 113/366 (30%), Positives = 154/366 (42%), Gaps = 44/366 (12%)

Query: 1639 ALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG 1698
            ++RL  G +   G VEV   G WGTVC   WD +DA+V+C QL  G    A      G G
Sbjct: 169  SVRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLG 228

Query: 1699 SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTT 1758
              PI   +VRC G+E  +  C    W    C     A V CS +   +       P    
Sbjct: 229  LIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPT------FPIIRL 282

Query: 1759 TARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1818
                S + G    Y +G + +     +   +A+ +            LG S +  +A H 
Sbjct: 283  AGGSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICR---------QLGLSGIA-KAWHQ 332

Query: 1819 CSFDYVEIFDGSLNSSLLLGKI-CNDTR----QIFTSSYNRMTIHFRSDISFQNTGFLAW 1873
              F       G  +  ++L ++ C        Q   SS+       + D     T     
Sbjct: 333  AYF-------GEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTPL--- 382

Query: 1874 YNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1933
                 +D  +RL     S+    GR+E+Y+ G WGTVCDD WT     VVCRQLG     
Sbjct: 383  -----TDGVIRLAGGKGSH---EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGK 434

Query: 1934 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC----SGNH 1989
             A  N +F   +GPI LDDV CSG E+   QC  R W  H+C+HRED  + C     G+ 
Sbjct: 435  QASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIACYPGGEGHR 493

Query: 1990 LSTPAP 1995
            LS   P
Sbjct: 494  LSLGFP 499



 Score =  112 bits (280), Expect = 4e-24
 Identities = 50/103 (48%), Positives = 66/103 (64%)

Query: 99  GLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFG 158
           G  +RL++G+ + +GRVE+   G WGT+CDD W   DA V+CRQLG      A   A+FG
Sbjct: 497 GFPVRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFG 556

Query: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC 201
           +G GPI +D+V+C+G+E  L  C       HNC H EDAGVIC
Sbjct: 557 EGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGVIC 599


>gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]
          Length = 607

 Score =  296 bits (759), Expect = 1e-79
 Identities = 160/412 (38%), Positives = 255/412 (61%), Gaps = 24/412 (5%)

Query: 1998 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE- 2056
            NI+ PN    CGG+L    G F+SP YP  +P  A CVW I+V+ +Y++ + F+++ LE 
Sbjct: 148  NISIPN----CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEI 203

Query: 2057 -GGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 2115
               C +D++ ++DGP  +S LI +VC     +F SSSN +++   +D++ + RGF A Y 
Sbjct: 204  DKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYT 263

Query: 2116 S--SPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLVISTWNGYYECRPQITPNLVIF 2173
            S  + + ++T+L C  + M+  +S+SYL++   + ++L +        CRP+++ N+V F
Sbjct: 264  SIYAENINTTSLTCSSDRMRVIISKSYLEAFNSNGNNLQLKDPT----CRPKLS-NVVEF 318

Query: 2174 TIPYSGCGTFKQADNDTIDYSNFLT--AAVSGGIIKRRTDLRIHVSCRMLQNTWVDTMYI 2231
            ++P +GCGT ++ ++ +I Y+N +T  A+ +  +I R+  L+I V C M  N+ V+ +YI
Sbjct: 319  SVPLNGCGTIRKVEDQSITYTNIITFSASSTSEVITRQKQLQIIVKCEMGHNSTVEIIYI 378

Query: 2232 ANDTIHVANNTIQVEEVQYGNFDVNISFYTSSSFLYPVTSRPYYVDLNQDLYVQAEILHS 2291
              D +  + N +       G ++ +++ + S+SF   +   PYYVDLNQ L+VQ  +  S
Sbjct: 379  TEDDVIQSQNAL-------GKYNTSMALFESNSFEKTILESPYYVDLNQTLFVQVSLHTS 431

Query: 2292 DAVLTLFVDTCVASPYSNDFTSLTYDLIRSGCVRDDTYGPYSSPSLRIARFRFRAFHFLN 2351
            D  L +F+DTC ASP S DF S TYDLI+SGC RD+T   Y        RF+F AF FL 
Sbjct: 432  DPNLVVFLDTCRASPTS-DFASPTYDLIKSGCSRDETCKVYPLFG-HYGRFQFNAFKFLR 489

Query: 2352 RFPSVYLRCKMVVCRAYDPSSRCYRGCVLRSKRDVGSYQEKVDVVLGPIQLQ 2403
               SVYL+CK+++C + D  SRC +GCV RSKRD+ SY+ K D ++GPI+L+
Sbjct: 490  SMSSVYLQCKVLICDSSDHQSRCNQGCVSRSKRDISSYKWKTDSIIGPIRLK 541



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 48/132 (36%), Positives = 73/132 (55%), Gaps = 6/132 (4%)

Query: 1765 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
            NCGG+L    G+F+SP+YP  +P  A CVW I+V   Y+I L F  + LE    C FD++
Sbjct: 153  NCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFL 212

Query: 1825 EIFDGSLNSSLLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1884
             I+DG   +S L+G++C      F SS N +T+   +D +    GF A Y S  ++    
Sbjct: 213  AIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE---- 268

Query: 1885 LVNLNSSYGLCA 1896
              N+N++   C+
Sbjct: 269  --NINTTSLTCS 278



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 5/91 (5%)

Query: 2034 CVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC--DGARGSFT 2089
            C W IE   N  + +IF  VQL+  G C  + I+VFDG   + PL+ +VC  +     F 
Sbjct: 58   CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117

Query: 2090 SSSNFMSIRFISDHS-ITRRGFRAEYYSSPS 2119
            SSS+ ++ + ++D + I R  F   Y+ SP+
Sbjct: 118  SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 3/91 (3%)

Query: 1792 CVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC--NDTRQIFT 1849
            C W IE      I + FS ++L+   +C  + +++FDG+ ++  LLG++C  ND   +F 
Sbjct: 58   CTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFE 117

Query: 1850 SSYNRMTIHFRSDIS-FQNTGFLAWYNSFPS 1879
            SS + +T    +D +  Q T F+ +Y   P+
Sbjct: 118  SSSSTLTFQIVTDSARIQRTVFVFYYFFSPN 148


>gi|5174411 CD5 molecule-like [Homo sapiens]
          Length = 347

 Score =  276 bits (707), Expect = 1e-73
 Identities = 146/350 (41%), Positives = 185/350 (52%), Gaps = 29/350 (8%)

Query: 359 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF 418
           S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A+  P    +
Sbjct: 20  SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 419 ---GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDT 475
               +    +++  V C+G E  L  C       ++C H EDAG  C    S  +P P+ 
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 476 LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 535
                             +RL +G   C+GRVEV ++  W TVC   W    A VVCRQL
Sbjct: 137 -----------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQL 179

Query: 536 GCGWAMLAPGNA-RFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
           GCG A+L      +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C 
Sbjct: 180 GCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECE 239

Query: 595 GPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 654
            P     LRLV G + C GR+EVL++G WG+VCDD+W   +  VVC+QLGCG + S    
Sbjct: 240 DP---FDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFR 296

Query: 655 AR--FGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 702
            R  +G G G I LD+VRCSG E  L  C +  W  H+C H ED  VICS
Sbjct: 297 DRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  275 bits (704), Expect = 3e-73
 Identities = 147/355 (41%), Positives = 183/355 (51%), Gaps = 39/355 (10%)

Query: 490 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF 549
           S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A   P    +
Sbjct: 20  SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 550 ---GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLA----- 601
               +    +++  V C+G E  L  C       ++C H EDAG  C  PESS +     
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPEG 137

Query: 602 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA-RFGQG 660
           +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGCG A        +   G
Sbjct: 138 VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYG 197

Query: 661 SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITL 720
             PI L  + CSG E+ L  CP+  W  + C H ED  V C                   
Sbjct: 198 RKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC------------------- 238

Query: 721 PPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAT 780
                  E    LRLV G + C GR+EVL++G WG+VCDD+W   +  VVC+QLGCG + 
Sbjct: 239 -------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSL 291

Query: 781 SAPGNAR--FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 833
           S     R  +G G G I LD+VRCSG E  L  C H  W  H+C H ED  VICS
Sbjct: 292 SPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346



 Score =  270 bits (689), Expect = 2e-71
 Identities = 147/372 (39%), Positives = 184/372 (49%), Gaps = 50/372 (13%)

Query: 230 SSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF 289
           S   +RLV G  RC GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A   P    +
Sbjct: 20  SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 290 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346
               +    +++  V C+G E  L  C       ++C H EDAG  C  P+S  +P P+ 
Sbjct: 80  EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 347 WPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGC 406
                           +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGC
Sbjct: 137 ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181

Query: 407 GWATSAPGNA-RFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA 465
           G A        +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C   
Sbjct: 182 GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238

Query: 466 HSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDT 525
                                  E    LRLV G + C GR+EVL++G WG+VCDD+W  
Sbjct: 239 -----------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGE 275

Query: 526 NDANVVCRQLGCGWAMLAPGNAR--FGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNC 583
            +  VVC+QLGCG ++      R  +G G G I LD+VRCSG E  L  C H  W  H+C
Sbjct: 276 KEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDC 335

Query: 584 GHSEDAGVICSG 595
            H ED  VICSG
Sbjct: 336 THQEDVAVICSG 347



 Score =  270 bits (689), Expect = 2e-71
 Identities = 147/371 (39%), Positives = 184/371 (49%), Gaps = 50/371 (13%)

Query: 858  SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARF 917
            S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A+  P    +
Sbjct: 20   SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 918  ---GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDT 974
                +    +++  V C+G E  L  C       ++C H EDAG  C    S  +P P+ 
Sbjct: 80   EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 975  LPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQL 1034
                              +RL +G   C+GRVEV +Q  W TVC   W    A VVCRQL
Sbjct: 137  -----------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQL 179

Query: 1035 GCGWAMSAPGNA-RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 1093
            GCG A+       +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C 
Sbjct: 180  GCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC- 238

Query: 1094 ASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDT 1153
                                   E    LRLV G + C GR+EVL++G WG+VCDD W  
Sbjct: 239  -----------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGE 275

Query: 1154 NDANVVCRQLGCGWAMSAPGNAR--FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNC 1211
             +  VVC+QLGCG ++S     R  +G G G I LD+VRCSG E  L  C H  W  H+C
Sbjct: 276  KEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDC 335

Query: 1212 GHHEDAGVICS 1222
             H ED  VICS
Sbjct: 336  THQEDVAVICS 346



 Score =  269 bits (688), Expect = 2e-71
 Identities = 147/371 (39%), Positives = 187/371 (50%), Gaps = 50/371 (13%)

Query: 1376 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF 1435
            S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A+  P    +
Sbjct: 20   SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 1436 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1492
                +    +++  V C+G E  L  C       ++C H EDAG  C   +S  +P P+ 
Sbjct: 80   EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 1493 WPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGC 1552
                            +RL +G   C+GRVEV +Q  W TVC   W    A VVCRQLGC
Sbjct: 137  ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181

Query: 1553 GWAMSAPGNA-QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAA 1611
            G A+       +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C   
Sbjct: 182  GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238

Query: 1612 QSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDT 1671
                                   E    LRLV G + C GR+EVL++G WG+VCDD+W  
Sbjct: 239  -----------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGE 275

Query: 1672 NDANVVCRQLGCGWAMSAPGNAR--FGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNC 1729
             +  VVC+QLGCG ++S     R  +G G G I LD+VRCSG E  L  C H+ W  H+C
Sbjct: 276  KEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDC 335

Query: 1730 GHHEDAGVICS 1740
             H ED  VICS
Sbjct: 336  THQEDVAVICS 346



 Score =  268 bits (684), Expect = 6e-71
 Identities = 145/367 (39%), Positives = 184/367 (50%), Gaps = 50/367 (13%)

Query: 733  LRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARF---G 789
            +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A+  P    +    
Sbjct: 24   VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 790  QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPDTWPTS 849
            +    +++  V C+G E  L  C       ++C H EDAG  C   +S  +P P+     
Sbjct: 84   EKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE----- 136

Query: 850  HASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWAT 909
                        +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGCG A 
Sbjct: 137  -----------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAV 185

Query: 910  SAPGNA-RFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWS 968
                   +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C       
Sbjct: 186  LTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC------- 238

Query: 969  TPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDAN 1028
                               E    LRLV G + C GR+EVL++G WG+VCDD+W   +  
Sbjct: 239  -------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQ 279

Query: 1029 VVCRQLGCGWAMSAPGNAR--FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSE 1086
            VVC+QLGCG ++S     R  +G G G I LD+VRCSG E  L  C H  W  H+C H E
Sbjct: 280  VVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQE 339

Query: 1087 DAGVICS 1093
            D  VICS
Sbjct: 340  DVAVICS 346



 Score =  266 bits (679), Expect = 2e-70
 Identities = 146/369 (39%), Positives = 183/369 (49%), Gaps = 48/369 (13%)

Query: 989  SSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 1048
            S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A   P    +
Sbjct: 20   SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 1049 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT 1105
                +    +++  V C+G E  L  C       ++C H EDAG  C   +S  +P P+ 
Sbjct: 80   EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 1106 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1165
                            +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGC
Sbjct: 137  ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181

Query: 1166 GWAMSAPGNA-RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1224
            G A+       +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C   
Sbjct: 182  GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238

Query: 1225 QSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTND 1284
                                 E    LRLV G + C GR+EVL++G WG+VCDD W   +
Sbjct: 239  ---------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKE 277

Query: 1285 ANVVCRQLGCGWATSAPGNAR--FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1342
              VVC+QLGCG + S     R  +G G G I LD+VRCSG E  L  C H  W  H+C H
Sbjct: 278  DQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTH 337

Query: 1343 HEDAGVICS 1351
             ED  VICS
Sbjct: 338  QEDVAVICS 346



 Score =  264 bits (675), Expect = 7e-70
 Identities = 145/369 (39%), Positives = 184/369 (49%), Gaps = 48/369 (13%)

Query: 1247 SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF 1306
            S   +RLV G  RC+GRVEV  +G WGTVCDD WD  D  V+CR+LGCG A+  P    +
Sbjct: 20   SPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILY 79

Query: 1307 ---GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1363
                +    +++  V C+G E  L  C       ++C H EDAG  C   +S  +P P+ 
Sbjct: 80   EPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVPE- 136

Query: 1364 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1423
                            +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGC
Sbjct: 137  ---------------GVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181

Query: 1424 GWATSAPGNA-RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAS 1482
            G A        +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C   
Sbjct: 182  GRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC--- 238

Query: 1483 QSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTND 1542
                                 E    LRLV G + C GR+EVL++G WG+VCDD W   +
Sbjct: 239  ---------------------EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKE 277

Query: 1543 ANVVCRQLGCGWAMSAPGNAQ--FGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1600
              VVC+QLGCG ++S     +  +G G G I LD+VRCSG E  L  C H  W  H+C H
Sbjct: 278  DQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTH 337

Query: 1601 HEDAGVICS 1609
             ED  VICS
Sbjct: 338  QEDVAVICS 346



 Score =  262 bits (670), Expect = 3e-69
 Identities = 148/368 (40%), Positives = 185/368 (50%), Gaps = 51/368 (13%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWF---G 158
           +RLV G  RC+GRVE+  +G WGTVCDD WD  D  V+CR+LGCG A   P    +    
Sbjct: 24  VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83

Query: 159 QGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVR 218
           +    + +  V C+G E  L  C       ++C H EDAG  C    P+S+         
Sbjct: 84  EKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCE--NPESSF-------- 131

Query: 219 ISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCG 278
              PVP EG      +RL +G   C+GRVEV ++  W TVC   W    A VVCRQLGCG
Sbjct: 132 --SPVP-EG------VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCG 182

Query: 279 WAMSAPGNA-QFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQ 337
            A+       +   G  PI L  + CSG E+ L  CP   W  + C H ED  V C  P 
Sbjct: 183 RAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDP- 241

Query: 338 SRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDA 397
                                    LRLV G + C GR+EVL++G WG+VCDD+W   + 
Sbjct: 242 -----------------------FDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKED 278

Query: 398 NVVCRQLGCGWATSAPGNAR--FGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 455
            VVC+QLGCG + S     R  +G G G I LD+VRCSG E  L  C H  W  H+C H 
Sbjct: 279 QVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQ 338

Query: 456 EDAGVICS 463
           ED  VICS
Sbjct: 339 EDVAVICS 346



 Score =  114 bits (286), Expect = 9e-25
 Identities = 54/107 (50%), Positives = 74/107 (69%), Gaps = 5/107 (4%)

Query: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA--LGNAY 1940
            LRLV  ++   LC+GR+E+ H G WG+VCDD+W  +E +VVC+QLGCG+++S        
Sbjct: 244  LRLVGGDN---LCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKC 300

Query: 1941 FGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG 1987
            +G G G I LD+V CSG E +L QC++R W  H+C H+ED  VICSG
Sbjct: 301  YGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG 347



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 46/101 (45%), Positives = 55/101 (54%), Gaps = 1/101 (0%)

Query: 1886 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSG 1944
            V L    G C GRVE+ H   W TVC   W+++ A+VVCRQLGCGRAV           G
Sbjct: 138  VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYG 197

Query: 1945 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
              PI L  + CSG E+TL  C +  W  + CNH ED  V C
Sbjct: 198  RKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVEC 238



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 42/105 (40%), Positives = 55/105 (52%), Gaps = 6/105 (5%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF---GSGSGPITLD 1951
            C GRVE+   G WGTVCDD W I++  V+CR+LGCG A        +         + + 
Sbjct: 33   CEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQ 92

Query: 1952 DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLS-TPAP 1995
             V C+GTE TL QC       ++C+H EDAG  C     S +P P
Sbjct: 93   SVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSFSPVP 135


>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
          Length = 756

 Score =  271 bits (692), Expect = 7e-72
 Identities = 196/539 (36%), Positives = 257/539 (47%), Gaps = 66/539 (12%)

Query: 594  SGPES--SLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 650
            S P+S  +  LRLV    + + GR+EVL++G WGTVCDD++   +A V CRQLG   A +
Sbjct: 22   SRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALT 81

Query: 651  APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 710
               +A++GQG GPI LD+VRC G ES L  C +NGW   +C H ED GVIC   + R   
Sbjct: 82   WAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGY- 140

Query: 711  RPDTLSTITLPPSTVGSESSLTLRLVNG---SDRCQGRVEVLYRGSWGTVCDDSWDTNDA 767
              +T+S    P      E  L   L +    S   +G VEV Y G W  VCD  W  N++
Sbjct: 141  LSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNS 200

Query: 768  NVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGHESYL 809
             VVC  L  G+ +  P ++ + +    + + D                  V C G E ++
Sbjct: 201  RVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHM 258

Query: 810  WSC-----PHNGWLSHNCGHHEDAGVICSVS-QSRPTPSPDTWPTSHASTAGPESSLALR 863
             +C     P  G L   C     A V C      RP   P T P    S A       +R
Sbjct: 259  ANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPRVR 312

Query: 864  LVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGP 923
            L +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   AR GQG GP
Sbjct: 313  LRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGP 372

Query: 924  IVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAS 983
            I L +VRC GYE  L  CP      + CQH  DA V C      + P+      + L   
Sbjct: 373  IHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLAGG 426

Query: 984  TVGSESSLALRL-VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 1042
             +  E  L +++ VNG  R            WG+VC ++W   +A V CRQLG G+A+ A
Sbjct: 427  RIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAIHA 474

Query: 1043 PGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSED---AGVICSAS 1095
                 F  G   +  +V+  VRCSG E  L  C  +G +  +C H      AGV C  S
Sbjct: 475  YKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMDS 531



 Score =  271 bits (692), Expect = 7e-72
 Identities = 197/552 (35%), Positives = 259/552 (46%), Gaps = 89/552 (16%)

Query: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
           LRLV  + + + GR+E+L++G WGTVCDD++   +A V CRQLG   A++   +A +GQG
Sbjct: 32  LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91

Query: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206
            GPI LD+VRC G ES L  C  NGW   +C H ED GVIC              +A  P
Sbjct: 92  EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151

Query: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266
           Q     E   VR+ P + +    S +            G VEV Y G W  VCD  W  N
Sbjct: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198

Query: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308
           ++ VVC  L  G+    P ++ + +    + + D                  V C G E 
Sbjct: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256

Query: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGPESSLA 362
           ++ +C     P  G L   C     A V C A P  RP   P T P    S A       
Sbjct: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310

Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
           +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   AR GQG 
Sbjct: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370

Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLP 482
           GPI L +VRC GYE  L  CP      + CQH  DA V C      + P+      + L 
Sbjct: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLA 424

Query: 483 ASTVGSESSLALRL-VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541
              +  E  L +++ VNG  R            WG+VC ++W   +A V CRQLG G+A+
Sbjct: 425 GGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAI 472

Query: 542 LAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED---AGVIC-- 593
            A     F  G   +  +V+  VRCSG E  L  C  +G +  +C H      AGV C  
Sbjct: 473 HAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMD 530

Query: 594 SGPESSLALRLV 605
           S P+  +  +LV
Sbjct: 531 SAPDLVMNAQLV 542



 Score =  265 bits (678), Expect = 3e-70
 Identities = 188/525 (35%), Positives = 246/525 (46%), Gaps = 59/525 (11%)

Query: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
           PP     S  +  LRLV    +   GR+EVL++G WGTVCDD +   +A V CRQLG   
Sbjct: 19  PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78

Query: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
           A++   +A++GQG GPI LD+VRC G ES L  C  NGW   +C HSED GVIC   + R
Sbjct: 79  ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138

Query: 340 PTPSPDTWPTSHASTAGPE----SSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDD 390
              S        ++  GP+      + L+ +    +      +G VEV Y G W  VCD 
Sbjct: 139 GYLSETV-----SNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQ 193

Query: 391 SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRC 432
            W  +++ VVC  L  G+ +  P ++ + +    + + D                  V C
Sbjct: 194 GWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTC 251

Query: 433 SGYESYLWSC-----PHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVG 487
            G E ++ +C     P  G L   C     A V C A        P   P  T P     
Sbjct: 252 LGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVA-------GPHFRPPKTKPQRKGS 304

Query: 488 SESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNA 547
                 +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   A
Sbjct: 305 WAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGA 364

Query: 548 RFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL--ALRLV 605
           R GQG GPI L +VRC G E  L  CP      + C H  DA V C+ P       +RL 
Sbjct: 365 RLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLA 424

Query: 606 NGGDRCQGRVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG- 660
            G    +G +EV    +    WG+VC ++W   +A V CRQLG G+A  A     F  G 
Sbjct: 425 GGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGT 484

Query: 661 --SGPIVLDDVRCSGHESYLWSCPNNG--WLSHNCGHHEDAGVIC 701
             +  +V+  VRCSG E  L  C  +G    SH  G    AGV C
Sbjct: 485 PRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFL-AGVSC 528



 Score =  263 bits (672), Expect = 2e-69
 Identities = 193/556 (34%), Positives = 257/556 (46%), Gaps = 90/556 (16%)

Query: 467 SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDS 522
           +WS P+   L  + L   P S   S  +  LRLV    + + GR+EVL++G WGTVCDD+
Sbjct: 2   AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61

Query: 523 WDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN 582
           +   +A V CRQLG   A+    +A++GQG GPI LD+VRC G ES L  C  NGW   +
Sbjct: 62  FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121

Query: 583 CGHSEDAGVICS----------------GPE----SSLALRLVNGGDR-----CQGRVEV 617
           C HSED GVIC                 GP+      + L+ +    +      +G VEV
Sbjct: 122 CSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEV 181

Query: 618 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD--------- 668
            Y G W  VCD  W  N++ VVC  L  G+ +  P ++ + +    + + D         
Sbjct: 182 KYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLT 239

Query: 669 ---------VRCSGHESYLWSC-----PNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 714
                    V C G E ++ +C     P  G L   C     A V C A      P+   
Sbjct: 240 NKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK--- 296

Query: 715 LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 774
               T P           +RL +G+   +GRVEVL    WGTVCD  W+   A+VVCRQL
Sbjct: 297 ----TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQL 352

Query: 775 GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 834
           G G A  A   AR GQG GPI L +VRC G+E  L  CP      + C H  DA V C+V
Sbjct: 353 GFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV 412

Query: 835 SQSRPTPSPDTWPTSHASTAG---PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 891
                   P+    +    AG   PE  L           + +VEV     WG+VC ++W
Sbjct: 413 --------PNMGFQNQVRLAGGRIPEEGL----------LEVQVEVNGVPRWGSVCSENW 454

Query: 892 DTSDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGYESYLWSCPHNGWLS 948
             ++A V CRQLG G+A  A     F  G   +  +V+  VRCSG E  L  C  +G + 
Sbjct: 455 GLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV- 513

Query: 949 HNCQHSED---AGVIC 961
            +C H      AGV C
Sbjct: 514 -HCSHGGGRFLAGVSC 528



 Score =  261 bits (667), Expect = 6e-69
 Identities = 197/553 (35%), Positives = 252/553 (45%), Gaps = 59/553 (10%)

Query: 966  SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDS 1021
            +WS P+   L  + L   P S   S  +  LRLV    + + GR+EVL+QG WGTVCDD+
Sbjct: 2    AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61

Query: 1022 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1081
            +   +A V CRQLG   A++   +A++GQG GPI LD+VRC G ES L  C  NGW   +
Sbjct: 62   FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121

Query: 1082 CGHSEDAGVICSASQSR----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEV 1137
            C HSED GVIC   + R     T S    P            +           +G VEV
Sbjct: 122  CSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEV 181

Query: 1138 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD--------- 1188
             Y G W  VCD  W  N++ VVC  L  G+    P ++ + +    + + D         
Sbjct: 182  KYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLT 239

Query: 1189 ---------VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1234
                     V C G E ++ +C     P  G L   C     A V C A        P T
Sbjct: 240  NKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPH--FRPPKT 297

Query: 1235 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1294
             P    S A       +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG 
Sbjct: 298  KPQRKGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354

Query: 1295 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1354
            G A  A   AR GQG GPI L +VRC G+E  L  CP      + C H  DA V C+   
Sbjct: 355  GSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV-- 412

Query: 1355 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1414
                  P+    +    AG       R+   G   + +VEV     WG+VC + W   +A
Sbjct: 413  ------PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEA 459

Query: 1415 NVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLSHNC 1469
             V CRQLG G+A  A     F  G   +  +V+  VRCSG E  L  C  +G    SH  
Sbjct: 460  MVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGG 519

Query: 1470 GHHEDAGVICSAS 1482
            G    AGV C  S
Sbjct: 520  GRFL-AGVSCMDS 531



 Score =  261 bits (667), Expect = 6e-69
 Identities = 197/549 (35%), Positives = 252/549 (45%), Gaps = 68/549 (12%)

Query: 838  RPTPS-PDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDA 896
            +P PS P +  T+     GPES             +GR+EVL++G WGTVCDD++   +A
Sbjct: 18   QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67

Query: 897  NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSED 956
             V CRQLG   A +   +A++GQG GPI LD+VRC G ES L  C  NGW   +C HSED
Sbjct: 68   TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127

Query: 957  AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR---CQGRVEVLYQGS 1013
             GVIC         S +T+     P      E  L   L +        +G VEV Y+G 
Sbjct: 128  VGVICHPRRHRGYLS-ETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGH 186

Query: 1014 WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD-------------- 1059
            W  VCD  W  N++ VVC  L  G+    P ++ + +    + + D              
Sbjct: 187  WRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSF 244

Query: 1060 ----VRCSGHESYLWSC-----PHNGWLSHNCGHSEDAGVICSAS-QSRPTPSPDTWPTS 1109
                V C G E ++ +C     P  G L   C     A V C A    RP   P T P  
Sbjct: 245  WIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQR 301

Query: 1110 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1169
              S A       +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A 
Sbjct: 302  KGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358

Query: 1170 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1229
             A   AR GQG GPI L +VRC G+E  L  CP      + C H  DA V C+       
Sbjct: 359  EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV------ 412

Query: 1230 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 1289
              P+    +    AG       R+   G   + +VEV     WG+VC + W   +A V C
Sbjct: 413  --PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEAMVAC 463

Query: 1290 RQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLSHNCGHHE 1344
            RQLG G+A  A     F  G   +  +V+  VRCSG E  L  C  +G    SH  G   
Sbjct: 464  RQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFL 523

Query: 1345 DAGVICSAS 1353
             AGV C  S
Sbjct: 524  -AGVSCMDS 531



 Score =  259 bits (663), Expect = 2e-68
 Identities = 190/543 (34%), Positives = 247/543 (45%), Gaps = 81/543 (14%)

Query: 339 RPTPS-PDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDA 397
           +P PS P +  T+     GPES             +GR+EVL++G WGTVCDD++   +A
Sbjct: 18  QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67

Query: 398 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSED 457
            V CRQLG   A +   +A++GQG GPI LD+VRC G ES L  C  NGW   +C HSED
Sbjct: 68  TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127

Query: 458 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR---CQGRVEVLYRGS 514
            GVIC         S +T+     P      E  L   L +        +G VEV Y G 
Sbjct: 128 VGVICHPRRHRGYLS-ETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGH 186

Query: 515 WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDD-------------- 560
           W  VCD  W  N++ VVC  L  G+    P ++ + +    + + D              
Sbjct: 187 WRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSF 244

Query: 561 ----VRCSGNESYLWSC-----PHNGWLSHNCGHSEDAGVIC-SGPE------------- 597
               V C G E ++ +C     P  G L   C     A V C +GP              
Sbjct: 245 WIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGS 304

Query: 598 --SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 655
                 +RL +G    +GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A   A
Sbjct: 305 WAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGA 364

Query: 656 RFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTL 715
           R GQG GPI L +VRC G+E  L  CP      + C H  DA V C      + P     
Sbjct: 365 RLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQ 418

Query: 716 STITLPPSTVGSESSLTLRL-VNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 774
           + + L    +  E  L +++ VNG  R            WG+VC ++W   +A V CRQL
Sbjct: 419 NQVRLAGGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQL 466

Query: 775 GCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLSHNCGHHEDAG 829
           G G+A  A     F  G   +  +V+  VRCSG E  L  C  +G    SH  G    AG
Sbjct: 467 GLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFL-AG 525

Query: 830 VIC 832
           V C
Sbjct: 526 VSC 528



 Score =  254 bits (649), Expect = 7e-67
 Identities = 187/547 (34%), Positives = 244/547 (44%), Gaps = 70/547 (12%)

Query: 1227 QPTPS-PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1285
            QP PS P +  T+     G ES             +GR+EVL++G WGTVCDD +   +A
Sbjct: 18   QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67

Query: 1286 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1345
             V CRQLG   A +   +A++GQG GPI LD+VRC G ES L  C  NGW   +C H ED
Sbjct: 68   TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127

Query: 1346 AGVICSASQSQ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSW 1401
             GVIC   + +     T S    P            +           +G VEV Y G W
Sbjct: 128  VGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHW 187

Query: 1402 GTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD--------------- 1446
              VCD  W  N++ VVC  LG  + +  P ++ + +    + + D               
Sbjct: 188  RQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245

Query: 1447 ---VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1498
               V C G E ++ +C     P  G L   C     A V C A      P   T P  + 
Sbjct: 246  IHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK--TKPQRKG 303

Query: 1499 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1558
            S A       +RL +G     GRVEVL    WGTVCD  W+   A+VVCRQLG G A  A
Sbjct: 304  SWAEEPR---VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREA 360

Query: 1559 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1618
               A+ GQG GPI L +VRC G+E  L  CP      + C H  DA V C          
Sbjct: 361  LFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC---------- 410

Query: 1619 PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVC 1678
                   N+P +   ++  LA   +        +VEV     WG+VC ++W   +A V C
Sbjct: 411  -------NVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVAC 463

Query: 1679 RQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED- 1734
            RQLG G+A+ A     F  G   +  +V+  VRCSG E  L  C   G +  +C H    
Sbjct: 464  RQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGR 521

Query: 1735 --AGVIC 1739
              AGV C
Sbjct: 522  FLAGVSC 528



 Score =  211 bits (536), Expect = 9e-54
 Identities = 146/413 (35%), Positives = 184/413 (44%), Gaps = 47/413 (11%)

Query: 1356 QPTPS-PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1414
            QP PS P +  T+     G ES             +GR+EVL++G WGTVCDD +   +A
Sbjct: 18   QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67

Query: 1415 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1474
             V CRQLG   A +   +A++GQG GPI LD+VRC G ES L  C  NGW   +C H ED
Sbjct: 68   TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127

Query: 1475 AGVICSASQSQ----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW 1530
             GVIC   + +     T S    P  R         +            G VEV Y+G W
Sbjct: 128  VGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHW 187

Query: 1531 GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD--------------- 1575
              VCD  W  N++ VVC  LG  +    P ++ + +    + + D               
Sbjct: 188  RQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245

Query: 1576 ---VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1627
               V C G E ++ +C     P  G L   C     A V C A      P+         
Sbjct: 246  IHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTK------- 298

Query: 1628 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1687
            P           +RL +G     GRVEVL    WGTVCD  W+   A+VVCRQLG G A 
Sbjct: 299  PQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358

Query: 1688 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
             A   AR GQG GPI L +VRC G E  L  CP      + C H  DA V C+
Sbjct: 359  EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411



 Score =  110 bits (276), Expect = 1e-23
 Identities = 50/89 (56%), Positives = 63/89 (70%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
            GR+E+ H G WGTVCDD++ IQEA V CRQLG   A++   +A +G G GPI LD+V C 
Sbjct: 44   GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103

Query: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
            GTES+L QC + GW   +C+H ED GVIC
Sbjct: 104  GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 46/101 (45%), Positives = 52/101 (51%)

Query: 1886 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1945
            V L S   +  GRVE+     WGTVCD  W +  A VVCRQLG G A  AL  A  G G 
Sbjct: 311  VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370

Query: 1946 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            GPI L +V C G E TL  C       + C H  DA V C+
Sbjct: 371  GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)

Query: 1893 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1949
            GL   +VE+     WG+VC ++W + EA V CRQLG G A+ A    +F SG   +  + 
Sbjct: 432  GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491

Query: 1950 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1985
            +  V CSGTE  L QC+  G    +C+H   R  AGV C
Sbjct: 492  MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1942
            G VE+ + G W  VCD  WT+  + VVC  LG    V    + Y                
Sbjct: 177  GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236

Query: 1943 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1993
              +      +  V C GTE  +  C+      RG     C     A V C +G H   P
Sbjct: 237  SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295


>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
          Length = 774

 Score =  267 bits (683), Expect = 8e-71
 Identities = 188/556 (33%), Positives = 263/556 (47%), Gaps = 61/556 (10%)

Query: 191 CGHGEDAGVICSAAQPQSTLRPESWP---VRISPPVP------TEGSESSLALRLVNGGD 241
           C H      + +   P S  + +SWP        P P         + + + LRL     
Sbjct: 6   CSHLCSCLAMLALLSPLSLAQYDSWPHYPEYFQQPAPEYHQPQAPANVAKIQLRLAGQKR 65

Query: 242 R-CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD 300
           +   GRVEV Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD+
Sbjct: 66  KHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDN 125

Query: 301 VRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESS 360
           + C+G+E+ L +C  NGW   +C H+ED GV+CS  +       ++      +       
Sbjct: 126 LHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVED 185

Query: 361 LALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGN 415
           + +R +    R      +G VEV    +W  +CD  W   ++ VVC   G       PG 
Sbjct: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGE 239

Query: 416 ------------ARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHN------CQHSED 457
                       +R  Q   P  +D   C+G E+++ SC     +S +      C++   
Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296

Query: 458 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRGSWGT 517
           A V C     +S   P        P   +       +RL  G    +GRVEVL  G WGT
Sbjct: 297 AVVSCVPGQVFSPDGPSRFRKAYKPEQPL-------VRLRGGAYIGEGRVEVLKNGEWGT 349

Query: 518 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNG 577
           VCDD WD   A+VVCR+LG G A  A   +R GQG GPI L++++C+GNE  +  C  N 
Sbjct: 350 VCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA 409

Query: 578 WLSHNCGHSEDAGVICSGPESSL--ALRLVNGGDRCQGRVEVLYRGS----WGTVCDDSW 631
             S  C H EDAGV C+ P   L   LRL  G +  +GRVEVL   +    WG VC  +W
Sbjct: 410 -ESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNW 468

Query: 632 DTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNG--W 686
              +A VVCRQLG G+A++A     +  G   S  +V+  V+CSG E  L  C ++G   
Sbjct: 469 GIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDV 528

Query: 687 LSHNCGHHEDAGVICS 702
                G    AGV CS
Sbjct: 529 ACPQGGVQYGAGVACS 544



 Score =  256 bits (655), Expect = 1e-67
 Identities = 184/514 (35%), Positives = 253/514 (49%), Gaps = 70/514 (13%)

Query: 612  QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 671
            +GRVEV Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD++ C
Sbjct: 69   EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128

Query: 672  SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL 731
            +G+E+ L +C +NGW   +C H ED GV+CS  +       ++L  I    +       +
Sbjct: 129  TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSL--INQIENLNIQVEDI 186

Query: 732  TLRLVNGSDR-----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN- 785
             +R +  + R      +G VEV    +W  +CD  W   ++ VVC   G       PG  
Sbjct: 187  RIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGER 240

Query: 786  -----------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDA 828
                       +R  Q   P  +D   C+G E+++ SC     +S +      C +   A
Sbjct: 241  TYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPA 297

Query: 829  GVICSVSQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCD 888
             V C   Q     SPD  P+       PE  L +RL  G    +GRVEVL  G WGTVCD
Sbjct: 298  VVSCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCD 352

Query: 889  DSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLS 948
            D WD   A+VVCR+LG G A  A   +R GQG GPI L++++C+G E  +  C  N   S
Sbjct: 353  DKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ES 411

Query: 949  HNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEV 1008
              C H EDAGV C      +TP+             +G +    LRL  G +  +GRVEV
Sbjct: 412  QGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVEV 450

Query: 1009 LYQGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVR 1061
            L + +    WG VC  +W   +A VVCRQLG G+A +A     +  G   S  +V+  V+
Sbjct: 451  LVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVK 510

Query: 1062 CSGHESYLWSCPHNG--WLSHNCGHSEDAGVICS 1093
            CSG E  L  C H+G        G    AGV CS
Sbjct: 511  CSGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544



 Score =  255 bits (651), Expect = 4e-67
 Identities = 179/510 (35%), Positives = 245/510 (48%), Gaps = 66/510 (12%)

Query: 1003 QGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRC 1062
            +GRVEV Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD++ C
Sbjct: 69   EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128

Query: 1063 SGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLAL 1122
            +G+E+ L +C  NGW   +C H+ED GV+CS  +       ++      +       + +
Sbjct: 129  TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188

Query: 1123 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN--- 1174
            R +    R      +G VEV    +W  +CD +W   ++ VVC   G       PG    
Sbjct: 189  RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFG------FPGERTY 242

Query: 1175 ---------ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 1219
                     +R  Q   P  +D   C+G E+++ SC     +S +      C +   A V
Sbjct: 243  NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299

Query: 1220 ICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDY 1279
             C   Q     SPD  P+        E  L +RL  G    +GRVEVL  G WGTVCDD 
Sbjct: 300  SCVPGQ---VFSPD-GPSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354

Query: 1280 WDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1339
            WD   A+VVCR+LG G A  A   +R GQG GPI L++++C+G+E  +  C  N   S  
Sbjct: 355  WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQG 413

Query: 1340 CGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRG 1399
            C H EDAGV C                   +T        LRL  G +  +GRVEVL   
Sbjct: 414  CNHEEDAGVRC-------------------NTPAMGLQKKLRLNGGRNPYEGRVEVLVER 454

Query: 1400 S----WGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGH 1452
            +    WG VC   W   +A VVCRQLG G+A++A     +  G   S  +V+  V+CSG 
Sbjct: 455  NGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGT 514

Query: 1453 ESYLWSCPHNG--WLSHNCGHHEDAGVICS 1480
            E  L  C H+G        G    AGV CS
Sbjct: 515  ELSLAHCRHDGEDVACPQGGVQYGAGVACS 544



 Score =  254 bits (649), Expect = 7e-67
 Identities = 178/514 (34%), Positives = 242/514 (47%), Gaps = 68/514 (13%)

Query: 1261 QGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 1320
            +GRVEV Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD++ C
Sbjct: 69   EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128

Query: 1321 SGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLAL 1380
            +G+E+ L +C  NGW   +C H ED GV+CS  +       ++      +       + +
Sbjct: 129  TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIENLNIQVEDIRI 188

Query: 1381 RLVNGGDR-----CQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF 1435
            R +    R      +G VEV    +W  +CD +W   ++ VVC   G       PG   +
Sbjct: 189  RAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGERTY 242

Query: 1436 G------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN------CGHHEDAGV 1477
                         Q   P  +D   C+G E+++ SC     +S +      C +   A V
Sbjct: 243  NTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLPAVV 299

Query: 1478 ICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDY 1537
             C   Q      P     SR   A       +RL  G     GRVEVL  G WGTVCDD 
Sbjct: 300  SCVPGQVFSPDGP-----SRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDDK 354

Query: 1538 WDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1597
            WD   A+VVCR+LG G A  A   ++ GQG GPI L++++C+G+E  +  C  N   S  
Sbjct: 355  WDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNAE-SQG 413

Query: 1598 CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLY 1657
            C H EDAGV C                 N PA+ +  +    LRL  G +   GRVEVL 
Sbjct: 414  CNHEEDAGVRC-----------------NTPAMGLQKK----LRLNGGRNPYEGRVEVLV 452

Query: 1658 RGS----WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCS 1710
              +    WG VC  +W   +A VVCRQLG G+A +A     +  G   S  +V+  V+CS
Sbjct: 453  ERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCS 512

Query: 1711 GNESYLWSCPHKG--WLTHNCGHHEDAGVICSAT 1742
            G E  L  C H G        G    AGV CS T
Sbjct: 513  GTELSLAHCRHDGEDVACPQGGVQYGAGVACSET 546



 Score =  252 bits (643), Expect = 4e-66
 Identities = 184/523 (35%), Positives = 249/523 (47%), Gaps = 71/523 (13%)

Query: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRC 171
           +GRVE+ Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD++ C
Sbjct: 69  EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128

Query: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESS 231
           +G+E+ L +C  NGW   +C H ED GV+CS  +        S   +I            
Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGFKFDNSLINQIEN---LNIQVED 185

Query: 232 LALRLVNGGDRCR-----GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           + +R +    R R     G VEV    +W  +CD +W   ++ VVC   G       PG 
Sbjct: 186 IRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGF------PGE 239

Query: 287 AQFG------------QGSGPIVLDDVRCSGHESYLWSCPHNGWLTHN------CGHSED 328
             +             Q   P  +D   C+G E+++ SC     ++ +      C +   
Sbjct: 240 RTYNTKVYKMFASRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCENGLP 296

Query: 329 AGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVC 388
           A V C   Q     SPD  P+       PE  L +RL  G    +GRVEVL  G WGTVC
Sbjct: 297 AVVSCVPGQ---VFSPDG-PSRFRKAYKPEQPL-VRLRGGAYIGEGRVEVLKNGEWGTVC 351

Query: 389 DDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWL 448
           DD WD   A+VVCR+LG G A  A   +R GQG GPI L++++C+G E  +  C  N   
Sbjct: 352 DDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-E 410

Query: 449 SHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVE 508
           S  C H EDAGV C      +TP+             +G +    LRL  G +  +GRVE
Sbjct: 411 SQGCNHEEDAGVRC------NTPA-------------MGLQKK--LRLNGGRNPYEGRVE 449

Query: 509 VLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG---SGPIVLDDV 561
           VL   +    WG VC  +W   +A VVCRQLG G+A  A     +  G   S  +V+  V
Sbjct: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509

Query: 562 RCSGNESYLWSCPHNG--WLSHNCGHSEDAGVICSGPESSLAL 602
           +CSG E  L  C H+G        G    AGV CS     L L
Sbjct: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVL 552



 Score =  251 bits (640), Expect = 8e-66
 Identities = 178/513 (34%), Positives = 245/513 (47%), Gaps = 89/513 (17%)

Query: 373 QGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 432
           +GRVEV Y G WGTVCDD +    A+VVCR+LG   A S   ++ +G+G GPI LD++ C
Sbjct: 69  EGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHC 128

Query: 433 SGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 492
           +G E+ L +C  NGW   +C+H+ED GV+C         S   +P      S +    +L
Sbjct: 129 TGNEATLAACTSNGWGVTDCKHTEDVGVVC---------SDKRIPGFKFDNSLINQIENL 179

Query: 493 ALRLVNGGDRC------------QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCG-- 538
            +++ +   R             +G VEV    +W  +CD  W   ++ VVC   G    
Sbjct: 180 NIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGE 239

Query: 539 -------WAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN------CGH 585
                  + M A   +R  Q   P  +D   C+G E+++ SC     +S +      C +
Sbjct: 240 RTYNTKVYKMFA---SRRKQRYWPFSMD---CTGTEAHISSCKLGPQVSLDPMKNVTCEN 293

Query: 586 SEDAGVIC--------SGPE--------SSLALRLVNGGDRCQGRVEVLYRGSWGTVCDD 629
              A V C         GP             +RL  G    +GRVEVL  G WGTVCDD
Sbjct: 294 GLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRGGAYIGEGRVEVLKNGEWGTVCDD 353

Query: 630 SWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSH 689
            WD   A+VVCR+LG G A  A   +R GQG GPI L++++C+G+E  +  C  N   S 
Sbjct: 354 KWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDCKFNA-ESQ 412

Query: 690 NCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVL 749
            C H EDAGV C      +TP              +G +    LRL  G +  +GRVEVL
Sbjct: 413 GCNHEEDAGVRC------NTP-------------AMGLQKK--LRLNGGRNPYEGRVEVL 451

Query: 750 YRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRC 802
              +    WG VC  +W   +A VVCRQLG G+A++A     +  G   S  +V+  V+C
Sbjct: 452 VERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKC 511

Query: 803 SGHESYLWSCPHNG--WLSHNCGHHEDAGVICS 833
           SG E  L  C H+G        G    AGV CS
Sbjct: 512 SGTELSLAHCRHDGEDVACPQGGVQYGAGVACS 544



 Score =  145 bits (366), Expect = 5e-34
 Identities = 95/242 (39%), Positives = 120/242 (49%), Gaps = 32/242 (13%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           +RL  G    +GRVE+L  G WGTVCDD WD   A+VVCR+LG G A  A   +  GQG 
Sbjct: 326 VRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGI 385

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISP 221
           GPI L++++C+G+E  +  C  N   S  C H EDAGV C+                   
Sbjct: 386 GPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN------------------- 425

Query: 222 PVPTEGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDYWDTNDANVVCRQLGC 277
             P  G +    LRL  G +   GRVEVL   +    WG VC   W   +A VVCRQLG 
Sbjct: 426 -TPAMGLQKK--LRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGL 482

Query: 278 GWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG--WLTHNCGHSEDAGVI 332
           G+A +A     +  G   S  +V+  V+CSG E  L  C H+G        G    AGV 
Sbjct: 483 GFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDGEDVACPQGGVQYGAGVA 542

Query: 333 CS 334
           CS
Sbjct: 543 CS 544



 Score =  107 bits (266), Expect = 2e-22
 Identities = 46/94 (48%), Positives = 62/94 (65%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
            GRVE+Y+ G WGTVCDD ++I  A VVCR+LG   A S   ++ +G G GPI LD++ C+
Sbjct: 70   GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1990
            G E+TL  C + GW   +C H ED GV+CS   +
Sbjct: 130  GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163



 Score =  103 bits (256), Expect = 3e-21
 Identities = 47/94 (50%), Positives = 63/94 (67%)

Query: 1651 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCS 1710
            GRVEV Y G WGTVCDD +  + A+VVCR+LG   A S   ++ +G+G GPI LD++ C+
Sbjct: 70   GRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAKSWTASSSYGKGEGPIWLDNLHCT 129

Query: 1711 GNESYLWSCPHKGWLTHNCGHHEDAGVICSATQI 1744
            GNE+ L +C   GW   +C H ED GV+CS  +I
Sbjct: 130  GNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRI 163



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 46/102 (45%), Positives = 61/102 (59%), Gaps = 1/102 (0%)

Query: 1885 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1944
            LV L     +  GRVE+   G WGTVCDD W +  A VVCR+LG G A  A+  +  G G
Sbjct: 325  LVRLRGGAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQG 384

Query: 1945 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
             GPI L++++C+G E ++  C+     S  CNH EDAGV C+
Sbjct: 385  IGPIHLNEIQCTGNEKSIIDCKFNA-ESQGCNHEEDAGVRCN 425



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 38/99 (38%), Positives = 52/99 (52%), Gaps = 7/99 (7%)

Query: 1878 PSDATLRLVNLNSSYGLCAGRVEIY---HGG-TWGTVCDDSWTIQEAEVVCRQLGCGRAV 1933
            P+    + + LN       GRVE+    +G   WG VC  +W I EA VVCRQLG G A 
Sbjct: 427  PAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFAS 486

Query: 1934 SALGNAYFGSG---SGPITLDDVECSGTESTLWQCRNRG 1969
            +A    ++  G   S  + +  V+CSGTE +L  CR+ G
Sbjct: 487  NAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHDG 525



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 9/76 (11%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC--GRAVSALGNAYFGSGS----GPITL 1950
            G VE+  G TW  +CD  WT + + VVC   G    R  +      F S       P ++
Sbjct: 204  GYVEVKEGKTWKQICDKHWTAKNSRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSM 263

Query: 1951 DDVECSGTESTLWQCR 1966
            D   C+GTE+ +  C+
Sbjct: 264  D---CTGTEAHISSCK 276


>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
          Length = 753

 Score =  264 bits (675), Expect = 7e-70
 Identities = 185/546 (33%), Positives = 252/546 (46%), Gaps = 58/546 (10%)

Query: 1219 VICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1276
            ++CS+    P+PS  T P   A + G    LA     G  R   +GRVE+   G WGT+C
Sbjct: 18   LLCSSCLGSPSPS--TGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70

Query: 1277 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1336
            DD +    A+++CR+LG   AT    +A++G G+G I LD++ CSG E  +  C   GW 
Sbjct: 71   DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130

Query: 1337 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR-----CQG 1391
            + +C H EDAGVIC   +       +     H         + +R   G  R      +G
Sbjct: 131  NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEG 187

Query: 1392 RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDD 1446
             VEV     W  VCD  W  ++++VVC  L  G+ +    NA F      +      L  
Sbjct: 188  LVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLLAQRQQHSFGLHG 245

Query: 1447 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSEST 1506
            V C G E++L  C    + +++       G    +    P  +  +    +   +  +  
Sbjct: 246  VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASS-GQKKQQQSKPQGE 304

Query: 1507 LALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ 1566
              +RL  G     GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A   A+ GQ
Sbjct: 305  ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364

Query: 1567 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTN 1626
            G G I L +VRCSG E  LW CPH    + +C H +DAGV C                 N
Sbjct: 365  GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC-----------------N 407

Query: 1627 LPALTVGSESSLALRLVNGGDRCRGRVEVLYRG----SWGTVCDDSWDTNDANVVCRQLG 1682
            LP    G+E+   +RL  G  +  GRVEV   G     WG +C D W T +A V CRQLG
Sbjct: 408  LP--YTGAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLG 463

Query: 1683 CGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGWLTH----NCGHHEDAG 1736
             G+A        +        +V+  VRC+G E  L  C H G  TH      G    AG
Sbjct: 464  LGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRTGTRFTAG 521

Query: 1737 VICSAT 1742
            VICS T
Sbjct: 522  VICSET 527



 Score =  264 bits (675), Expect = 7e-70
 Identities = 180/536 (33%), Positives = 245/536 (45%), Gaps = 52/536 (9%)

Query: 840  TPSPDTWPTSHASTAGPESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDAN 897
            +PSP T P   A + G    LA     G  R   +GRVE+   G WGT+CDD +    A+
Sbjct: 26   SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAH 80

Query: 898  VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDA 957
            ++CR+LG   AT    +A++G G+G I LD++ CSG E  +  C   GW + +C H EDA
Sbjct: 81   ILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDA 140

Query: 958  GVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR-----CQGRVEVLYQG 1012
            GVIC          P    +  +          + +R   G  R      +G VEV    
Sbjct: 141  GVICKDQRL-----PGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPD 195

Query: 1013 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF-----GQGSGPIVLDDVRCSGHES 1067
             W  VCD  W  ++++VVC  LG  +      NA F      +      L  V C G E+
Sbjct: 196  GWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEA 253

Query: 1068 YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 1127
            +L  C    + +++       G    +    P  +  +       +   +    +RL  G
Sbjct: 254  HLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK-PQGEARVRLKGG 312

Query: 1128 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1187
                +GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A   AR GQG G I L 
Sbjct: 313  AHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLS 372

Query: 1188 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES 1247
            +VRCSG E  LW CPH    + +C H +DAGV C+             P + A T     
Sbjct: 373  EVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL------------PYTGAET----- 415

Query: 1248 SLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 1303
               +RL  G  + +GRVEV   G     WG +C D W T +A V CRQLG G+A      
Sbjct: 416  --RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE 473

Query: 1304 ARFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDAGVICSASQS 1355
              +        +V+  VRC+G E  L  C H+G        G    AGVICS + S
Sbjct: 474  TWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETAS 529



 Score =  262 bits (670), Expect = 3e-69
 Identities = 178/513 (34%), Positives = 236/513 (46%), Gaps = 37/513 (7%)

Query: 220 SPPVPTEGSESSLALRLVNGG---DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276
           SP    E    S  LR    G       GRVE+   G WGT+CDD +    A+++CR+LG
Sbjct: 28  SPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELG 87

Query: 277 CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336
              A     +A++G G+G I LD++ CSG E  +  C   GW   +C H EDAGVIC   
Sbjct: 88  FTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQ 147

Query: 337 QSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDS 391
           +       +     H         + +R   G  R      +G VEV     W  VCD  
Sbjct: 148 RLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKG 204

Query: 392 WDTSDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDDVRCSGYESYLWSCPHNG 446
           W   +++VVC  LG  + +    NA F      +      L  V C G E++L  C    
Sbjct: 205 WSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEF 262

Query: 447 WLSHN---CQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRC 503
           + +++   C     A V C     ++  S       + P      +    +RL  G    
Sbjct: 263 YRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP------QGEARVRLKGGAHPG 316

Query: 504 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRC 563
           +GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A   AR GQG G I L +VRC
Sbjct: 317 EGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRC 376

Query: 564 SGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQ--GRVEVLYRG 621
           SG E  LW CPH    + +C HS+DAGV C+ P +    R+   G R Q  GRVEV   G
Sbjct: 377 SGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGG 436

Query: 622 ----SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSG--PIVLDDVRCSGHE 675
                WG +C D W T +A V CRQLG G+A        +        +V+  VRC+G E
Sbjct: 437 PGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTE 496

Query: 676 SYLWSCPNNGW--LSHNCGHHEDAGVICSAAQS 706
             L  C ++G        G    AGVICS   S
Sbjct: 497 LSLDQCAHHGTHITCKRTGTRFTAGVICSETAS 529



 Score =  262 bits (670), Expect = 3e-69
 Identities = 172/504 (34%), Positives = 240/504 (47%), Gaps = 47/504 (9%)

Query: 612  QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 671
            +GRVE+   G WGT+CDD +    A+++CR+LG   AT    +A++G G+G I LD++ C
Sbjct: 55   EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114

Query: 672  SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL 731
            SG E  +  C + GW + +C H EDAGVIC   + +  P     + I +       E  +
Sbjct: 115  SGTEQSVTECASRGWGNSDCTHDEDAGVIC---KDQRLPGFSDSNVIEVEHHLQVEE--V 169

Query: 732  TLRLVNGSDR-----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 786
             +R   G  R      +G VEV     W  VCD  W  ++++VVC  LG  + +    NA
Sbjct: 170  RIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNA 227

Query: 787  RF-----GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTP 841
             F      +      L  V C G E++L  C    + +++       G         P  
Sbjct: 228  AFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVY 287

Query: 842  SPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCR 901
            +  +       +  P+    +RL  G    +GRVEVL   +WGTVCD  WD   A+VVCR
Sbjct: 288  AASSGQKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCR 346

Query: 902  QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 961
            +LG G A  A   AR GQG G I L +VRCSG E  LW CPH    + +C HS+DAGV C
Sbjct: 347  ELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406

Query: 962  SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQG----SWGTV 1017
            +  ++                   G+E+   +RL  G  + +GRVEV   G     WG +
Sbjct: 407  NLPYT-------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLI 445

Query: 1018 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGHESYLWSCPHN 1075
            C D W T +A V CRQLG G+A        +        +V+  VRC+G E  L  C H+
Sbjct: 446  CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH 505

Query: 1076 GW--LSHNCGHSEDAGVICSASQS 1097
            G        G    AGVICS + S
Sbjct: 506  GTHITCKRTGTRFTAGVICSETAS 529



 Score =  261 bits (666), Expect = 8e-69
 Identities = 181/544 (33%), Positives = 248/544 (45%), Gaps = 52/544 (9%)

Query: 1090 VICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1147
            ++CS+     +PSP T P   A + G    LA     G  R   +GRVE+   G WGT+C
Sbjct: 18   LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70

Query: 1148 DDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1207
            DD +    A+++CR+LG   A     +A++G G+G I LD++ CSG E  +  C   GW 
Sbjct: 71   DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130

Query: 1208 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR-----CQG 1262
            + +C H EDAGVIC   +       +     H         + +R   G  R      +G
Sbjct: 131  NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEG 187

Query: 1263 RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDD 1317
             VEV     W  VCD  W  ++++VVC  L  G+ +    NA F      +      L  
Sbjct: 188  LVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLLAQRQQHSFGLHG 245

Query: 1318 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESS 1377
            V C G E++L  C    + +++       G    +    P  +  +       +   +  
Sbjct: 246  VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK-PQGE 304

Query: 1378 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQ 1437
              +RL  G    +GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A   AR GQ
Sbjct: 305  ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364

Query: 1438 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSR 1497
            G G I L +VRCSG E  LW CPH    + +C H +DAGV C+             P + 
Sbjct: 365  GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL------------PYTG 412

Query: 1498 ASTAGSESTLALRLVNGGDRCRGRVEVLYQG----SWGTVCDDYWDTNDANVVCRQLGCG 1553
            A T        +RL  G  +  GRVEV   G     WG +C D W T +A V CRQLG G
Sbjct: 413  AET-------RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLG 465

Query: 1554 WAMSAPGNAQFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDAGVICS 1609
            +A        +        +V+  VRC+G E  L  C H+G        G    AGVICS
Sbjct: 466  YANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525

Query: 1610 AAQS 1613
               S
Sbjct: 526  ETAS 529



 Score =  259 bits (661), Expect = 3e-68
 Identities = 188/563 (33%), Positives = 256/563 (45%), Gaps = 53/563 (9%)

Query: 59  TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117
           +V + SP  L   L  +   GS  PS ST      +    GL  RL     +  +GRVEI
Sbjct: 5   SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60

Query: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177
              G WGT+CDD +    A+++CR+LG   A     +A +G G+G I LD++ CSG E  
Sbjct: 61  QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120

Query: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237
           +  C   GW + +C H EDAGVIC   +       +S  + +   +  E     + +R  
Sbjct: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174

Query: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289
            G  R       G VEV     W  VCD  W  ++++VVC  L  G+      NA F   
Sbjct: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRL 232

Query: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347
              +      L  V C G E++L  C    +  ++       G    +    P  +  + 
Sbjct: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292

Query: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
                 +  P+    +RL  G    +GRVEVL   +WGTVCD  WD   A+VVCR+LG G
Sbjct: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351

Query: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
            A  A   AR GQG G I L +VRCSG E  LW CPH    + +C HS+DAGV C+  ++
Sbjct: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411

Query: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDSW 523
                              G+E+   +RL  G  + +GRVEV   G     WG +C D W
Sbjct: 412 -------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDW 450

Query: 524 DTNDANVVCRQLGCGWAMLAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHNGW--L 579
            T +A V CRQLG G+A        +        +V+  VRC+G E  L  C H+G    
Sbjct: 451 GTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHIT 510

Query: 580 SHNCGHSEDAGVICSGPESSLAL 602
               G    AGVICS   S L L
Sbjct: 511 CKRTGTRFTAGVICSETASDLLL 533



 Score =  211 bits (538), Expect = 5e-54
 Identities = 143/416 (34%), Positives = 193/416 (46%), Gaps = 33/416 (7%)

Query: 1348 VICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1405
            ++CS+    P+PS  T P   A + G    LA     G  R   +GRVE+   G WGT+C
Sbjct: 18   LLCSSCLGSPSPS--TGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70

Query: 1406 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1465
            DD +    A+++CR+LG   AT    +A++G G+G I LD++ CSG E  +  C   GW 
Sbjct: 71   DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130

Query: 1466 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDR-----CRG 1520
            + +C H EDAGVIC   + Q  P                  + +R   G  R       G
Sbjct: 131  NSDCTHDEDAGVIC---KDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEG 187

Query: 1521 RVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDD 1575
             VEV     W  VCD  W  ++++VVC  LG  +      NA F      +      L  
Sbjct: 188  LVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHG 245

Query: 1576 VRCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTV 1632
            V C G E++L  C    + +++   C     A V C      +          + P    
Sbjct: 246  VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP---- 301

Query: 1633 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 1692
              +    +RL  G     GRVEVL   +WGTVCD  WD + A+VVCR+LG G A  A   
Sbjct: 302  --QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSG 359

Query: 1693 ARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 1748
            AR GQG G I L +VRCSG E  LW CPHK     +C H +DAGV C+     + T
Sbjct: 360  ARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415



 Score =  107 bits (266), Expect = 2e-22
 Identities = 46/94 (48%), Positives = 63/94 (67%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
            GRVEI   G WGT+CDD +T+Q A ++CR+LG   A     +A +G G+G I LD++ CS
Sbjct: 56   GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115

Query: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1990
            GTE ++ +C +RGW + +C H EDAGVIC    L
Sbjct: 116  GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 44/90 (48%), Positives = 57/90 (63%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
            GRVE+    TWGTVCD  W +  A VVCR+LG G A  AL  A  G G G I L +V CS
Sbjct: 318  GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377

Query: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            G E +LW+C ++   + +C+H +DAGV C+
Sbjct: 378  GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 1897 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1950
            GRVE+  GG     WG +C D W   EA V CRQLG G A   L    Y+ SG+   + +
Sbjct: 428  GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487

Query: 1951 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1986
              V C+GTE +L QC + G          R  AGVICS
Sbjct: 488  SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1953
            G VE+     W  VCD  W+   + VVC  LG     R  +A              L  V
Sbjct: 187  GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246

Query: 1954 ECSGTESTLWQC 1965
             C GTE+ L  C
Sbjct: 247  ACVGTEAHLSLC 258


>gi|194018748 CD6 molecule [Homo sapiens]
          Length = 668

 Score =  250 bits (639), Expect = 1e-65
 Identities = 165/433 (38%), Positives = 208/433 (48%), Gaps = 65/433 (15%)

Query: 330 GVICSAPQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 386
           G++ +A    P+P+P D   TS A +    P   L +RL NG   C G VEV    SW  
Sbjct: 9   GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 387 VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 431
            C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 69  ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128

Query: 432 CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 490
           CSG E  L        + H C+     A V C+                           
Sbjct: 129 CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157

Query: 491 SLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFG 550
           + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F 
Sbjct: 158 NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217

Query: 551 QGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDR 610
            G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  +S    RL  G DR
Sbjct: 218 PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS---WRLTGGADR 273

Query: 611 CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVR 670
           C+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A   P        SG +      
Sbjct: 274 CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS--- 329

Query: 671 CSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPS--TVGSE 728
           C+G E  L +C      S+ C     A V+CSA++S        LST  +P S  TV  E
Sbjct: 330 CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL-----HNLSTPEVPASVQTVTIE 384

Query: 729 SSLTLRLVNGSDR 741
           SS+T+++ N   R
Sbjct: 385 SSVTVKIENKESR 397



 Score =  243 bits (619), Expect = 2e-63
 Identities = 163/450 (36%), Positives = 204/450 (45%), Gaps = 80/450 (17%)

Query: 829  GVICSVSQSRPTPSP-DTWPTSHASTA--GPESSLALRLVNGGDRCQGRVEVLYRGSWGT 885
            G++ +     P+P+P D   TS A +    P   L +RL NG   C G VEV    SW  
Sbjct: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 886  VCDDSWDTSDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 930
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128

Query: 931  CSGYESYLWSCPHNGWLSHNCQHS-EDAGVICSAAHSWSTPSPDTLPTITLPASTVGSES 989
            CSG E  L        + H C+     A V C+                           
Sbjct: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCA--------------------------E 157

Query: 990  SLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 1049
            + ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F 
Sbjct: 158  NRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFT 217

Query: 1050 QGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTS 1109
             G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W   
Sbjct: 218  PGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W--- 265

Query: 1110 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1169
                         RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312

Query: 1170 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1229
              P        SG +      C+G E  L +C      S+ C     A V+CSAS+S   
Sbjct: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368

Query: 1230 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1259
             S    P S   T   ESS+ +++ N   R
Sbjct: 369  LSTPEVPAS-VQTVTIESSVTVKIENKESR 397



 Score =  241 bits (615), Expect = 6e-63
 Identities = 160/450 (35%), Positives = 201/450 (44%), Gaps = 78/450 (17%)

Query: 698  GVICSAAQSRSTPRP-DTLSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGT 756
            G++ +A     +P P D L+T +           L +RL NGS  C G VEV    SW  
Sbjct: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 757  VCDDSWDTNDANVVCRQLGCGWATS---------------APGNARFGQGSGPIVLDDVR 801
             C   WD+  A  VCR LGCG A +               A GN      +       + 
Sbjct: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128

Query: 802  CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSVSQSRPTPSPDTWPTSHASTAGPESSL 860
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159

Query: 861  ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQG 920
            ALRLV+GG  C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219

Query: 921  SGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITL 980
             GPI  D V CSG E+YLW CP      H C H EDAG +CS   SW             
Sbjct: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSW------------- 265

Query: 981  PASTVGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1040
                         RL  G DRC+G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312

Query: 1041 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPT 1100
              P        SG +      C+G E  L +C      S+ C  S  A V+CSAS+S   
Sbjct: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHN 368

Query: 1101 PSPDTWPTSHASTAGSESSLALRLVNGGDR 1130
             S    P S   T   ESS+ +++ N   R
Sbjct: 369  LSTPEVPAS-VQTVTIESSVTVKIENKESR 397



 Score =  239 bits (611), Expect = 2e-62
 Identities = 163/448 (36%), Positives = 202/448 (45%), Gaps = 78/448 (17%)

Query: 1089 GVICSASQSRPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1145
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 1146 VCDDYWDTNDANVVCRQLGCGWAMSAP---------------GNARFGQGSGPIVLDDVR 1190
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128

Query: 1191 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1249
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159

Query: 1250 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1309
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219

Query: 1310 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHA 1369
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265

Query: 1370 STAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSA 1429
                       RL  G DRC+G+VEV +RG W TVCD  W  ++A V+C+ LGCG A   
Sbjct: 266  -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314

Query: 1430 PGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPS 1489
            P        SG +      C+G E  L +C      S+ C     A V+CSAS+S    S
Sbjct: 315  PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370

Query: 1490 PDTWPTSRASTAGSESTLALRLVNGGDR 1517
                P S   T   ES++ +++ N   R
Sbjct: 371  TPEVPAS-VQTVTIESSVTVKIENKESR 397



 Score =  238 bits (608), Expect = 4e-62
 Identities = 161/437 (36%), Positives = 201/437 (45%), Gaps = 89/437 (20%)

Query: 86  STLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGC 145
           S+ ES + E  +  L +RL NG   C G VE+    SW   C   WD+  A  VCR LGC
Sbjct: 30  SSAESELWEPGER-LPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGC 88

Query: 146 GWAMSAP---------------GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHN 190
           G A +A                GN      +       + CSG E  L        + H 
Sbjct: 89  GGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCEV-----VEHA 143

Query: 191 C-GHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEV 249
           C   G  A V C+                            + ALRLV+GG  C GRVE+
Sbjct: 144 CRSDGRRARVTCA---------------------------ENRALRLVDGGGACAGRVEM 176

Query: 250 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESY 309
           L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG E+Y
Sbjct: 177 LEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAY 236

Query: 310 LWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGG 369
           LW CP      H CGH EDAG +CS  QS        W                RL  G 
Sbjct: 237 LWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----------------RLTGGA 271

Query: 370 DRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD 429
           DRC+G+VEV +RG W TVCD  W  S+A V+C+ LGCG A   P        SG +    
Sbjct: 272 DRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS- 329

Query: 430 VRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAA---HSWSTPS-PDTLPTITLPAST 485
             C+G E  L +C      S+ C  S  A V+CSA+   H+ STP  P ++ T+T+    
Sbjct: 330 --CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTPEVPASVQTVTI---- 383

Query: 486 VGSESSLALRLVNGGDR 502
              ESS+ +++ N   R
Sbjct: 384 ---ESSVTVKIENKESR 397



 Score =  238 bits (606), Expect = 7e-62
 Identities = 155/411 (37%), Positives = 197/411 (47%), Gaps = 57/411 (13%)

Query: 596  PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 655
            P   L +RL NG   C G VEV    SW   C   WD+  A  VCR LGCG A +A    
Sbjct: 39   PGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA---- 94

Query: 656  RFGQGSGPIV-LDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 714
               Q + P   L     +G+ S          ++ N        ++CS A+ R     + 
Sbjct: 95   --SQLAPPTPELPPPPAAGNTS----------VAANATLAGAPALLCSGAEWRLCEVVEH 142

Query: 715  LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 774
                    + V    +  LRLV+G   C GRVE+L  G WG+VCDD+WD  DA+VVCRQL
Sbjct: 143  ACRSDGRRARVTCAENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQL 202

Query: 775  GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 834
            GCGWA  A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS 
Sbjct: 203  GCGWAVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE 261

Query: 835  SQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 894
             QS        W                RL  G DRC+G+VEV +RG W TVCD  W  S
Sbjct: 262  HQS--------W----------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPS 297

Query: 895  DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHS 954
            +A V+C+ LGCG A   P        SG +      C+G E  L +C      S+ C  S
Sbjct: 298  EAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQS 353

Query: 955  EDAGVICSAA---HSWSTPS-PDTLPTITLPASTVGSESSLALRLVNGGDR 1001
              A V+CSA+   H+ STP  P ++ T+T+       ESS+ +++ N   R
Sbjct: 354  LAARVLCSASRSLHNLSTPEVPASVQTVTI-------ESSVTVKIENKESR 397



 Score =  235 bits (600), Expect = 3e-61
 Identities = 163/452 (36%), Positives = 204/452 (45%), Gaps = 84/452 (18%)

Query: 1218 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1274
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 1275 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1319
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128

Query: 1320 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSL 1378
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159

Query: 1379 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQG 1438
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA  A     F  G
Sbjct: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219

Query: 1439 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1498
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265

Query: 1499 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1558
                       RL  G DRC G+VEV ++G W TVCD  W  ++A V+C+ LGCG A+  
Sbjct: 266  -----------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVER 314

Query: 1559 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1618
            P        SG +      C+G E  L +C      S+ C     A V+CSA++S     
Sbjct: 315  PKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSL---- 366

Query: 1619 PDTWLTTNLPA--LTVGSESSLALRLVNGGDR 1648
                 T  +PA   TV  ESS+ +++ N   R
Sbjct: 367  -HNLSTPEVPASVQTVTIESSVTVKIENKESR 397



 Score =  232 bits (591), Expect = 4e-60
 Identities = 152/416 (36%), Positives = 190/416 (45%), Gaps = 79/416 (18%)

Query: 1347 GVICSASQSQPTPSP-DTWPTSHASTAGSESS--LALRLVNGGDRCQGRVEVLYRGSWGT 1403
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV    SW  
Sbjct: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 1404 VCDDYWDTNDANVVCRQLGCGWATSAP---------------GNARFGQGSGPIVLDDVR 1448
             C   WD+  A  VCR LGCG A +A                GN      +       + 
Sbjct: 69   ACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALL 128

Query: 1449 CSGHESYLWSCPHNGWLSHNC-GHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 1507
            CSG E  L        + H C      A V C+ ++                        
Sbjct: 129  CSGAEWRLCEV-----VEHACRSDGRRARVTCAENR------------------------ 159

Query: 1508 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 1567
            ALRLV+GG  C GRVE+L  G WG+VCDD WD  DA+VVCRQLGCGWA+ A     F  G
Sbjct: 160  ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPG 219

Query: 1568 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1627
             GPI  D V CSG E+YLW CP      H CGH EDAG +CS  QS        W     
Sbjct: 220  RGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQS--------W----- 265

Query: 1628 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1687
                         RL  G DRC G+VEV +RG W TVCD  W  ++A V+C+ LGCG A+
Sbjct: 266  -------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV 312

Query: 1688 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQ 1743
              P        SG +      C+G E  L +C  +   ++ C     A V+CSA++
Sbjct: 313  ERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASR 364



 Score =  200 bits (508), Expect = 2e-50
 Identities = 133/344 (38%), Positives = 164/344 (47%), Gaps = 44/344 (12%)

Query: 31  ASLIPSEVPLDPTVAEGSPFPSESTLESTVAEGSPISLESTLE---STVAEGSLIPSEST 87
           + L P    L P  A G+     S   +    G+P  L S  E     V E +       
Sbjct: 95  SQLAPPTPELPPPPAAGNT----SVAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRR 150

Query: 88  LESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGW 147
              T AE      ALRLV+G G C GRVE+L  G WG+VCDD+WD  DA+VVCRQLGCGW
Sbjct: 151 ARVTCAENR----ALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206

Query: 148 AMSAPGNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQ 207
           A+ A     F  G GPI  D V CSG E+YLW CP      H CGH EDAG +CS  Q  
Sbjct: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQ-- 263

Query: 208 STLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTND 267
                 SW                   RL  G DRC G+VEV +RG W TVCD  W  ++
Sbjct: 264 ------SW-------------------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSE 298

Query: 268 ANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSE 327
           A V+C+ LGCG A+  P        SG +      C+G E  L +C      ++ C  S 
Sbjct: 299 AKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSL 354

Query: 328 DAGVICSAPQSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR 371
            A V+CSA +S    S    P S   T   ESS+ +++ N   R
Sbjct: 355 AARVLCSASRSLHNLSTPEVPAS-VQTVTIESSVTVKIENKESR 397



 Score =  180 bits (456), Expect = 2e-44
 Identities = 122/351 (34%), Positives = 158/351 (45%), Gaps = 49/351 (13%)

Query: 1476 GVICSASQSQPTPSP-DTWPTSRASTAGSE--STLALRLVNGGDRCRGRVEVLYQGSWGT 1532
            G++ +A    P+P+P D   TS A +   E    L +RL NG   C G VEV  + SW  
Sbjct: 9    GLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEP 68

Query: 1533 VCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIV-LDDVRCSGHESYLWSCPHN 1591
             C   WD+  A  VCR LGCG A +A       Q + P   L     +G+ S        
Sbjct: 69   ACGALWDSRAAEAVCRALGCGGAEAA------SQLAPPTPELPPPPAAGNTS-------- 114

Query: 1592 GWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRG 1651
              ++ N        ++CS A+ +     +    ++     V    + ALRLV+GG  C G
Sbjct: 115  --VAANATLAGAPALLCSGAEWRLCEVVEHACRSDGRRARVTCAENRALRLVDGGGACAG 172

Query: 1652 RVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSG 1711
            RVE+L  G WG+VCDD+WD  DA+VVCRQLGCGWA+ A     F  G GPI  D V CSG
Sbjct: 173  RVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCSG 232

Query: 1712 NESYLWSCPHKGWLTHNCGHHEDAGVICSATQI----------------------NSTTT 1749
             E+YLW CP      H CGH EDAG +CS  Q                       N+   
Sbjct: 233  AEAYLWDCPGLPG-QHYCGHKEDAGAVCSEHQSWRLTGGADRCEGQVEVHFRGVWNTVCD 291

Query: 1750 DWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNN------AKCVW 1794
              W+P+       S  CG  +    G   S S   YY  N      + C W
Sbjct: 292  SEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYYSCNGEELTLSNCSW 342



 Score =  117 bits (292), Expect = 2e-25
 Identities = 54/103 (52%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 1884 RLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGS 1943
            R + L    G CAGRVE+   G WG+VCDD+W +++A VVCRQLGCG AV AL   +F  
Sbjct: 159  RALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218

Query: 1944 GSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            G GPI  D V CSG E+ LW C       H C H+EDAG +CS
Sbjct: 219  GRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCS 260



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 41/111 (36%), Positives = 54/111 (48%), Gaps = 24/111 (21%)

Query: 1895 CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV--------SALGNAYFGSGSG 1946
            C G+VE++  G W TVCD  W   EA+V+C+ LGCG AV        S  G  Y+     
Sbjct: 274  CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMYY----- 328

Query: 1947 PITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSG----NHLSTP 1993
                    C+G E TL  C  R   S+ C+    A V+CS     ++LSTP
Sbjct: 329  -------SCNGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLSTP 372



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 23/53 (43%), Positives = 30/53 (56%), Gaps = 3/53 (5%)

Query: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1935
            +RL N +SS   C+G VE+    +W   C   W  + AE VCR LGCG A +A
Sbjct: 45   VRLTNGSSS---CSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAA 94


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score =  151 bits (381), Expect = 9e-36
 Identities = 114/393 (29%), Positives = 176/393 (44%), Gaps = 54/393 (13%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CG  L  ++G  SSP +P  YP+   C+W + V  G +I L F+ + L     C +DY+E
Sbjct: 349  CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408

Query: 1826 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF------P 1878
            + DG    S LLG+ C D   ++ TS+ +RM I FRS  ++   GF A Y +        
Sbjct: 409  VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIRK 468

Query: 1879 SDATLRLVNLNSSYGL---CAGRV---EIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG-- 1930
            ++  ++  N    Y     C  ++   E YH G          T Q  E+  R   C   
Sbjct: 469  NEGQIQSPNYPDDYRPMKECVWKITVSESYHVGL---------TFQSFEIE-RHDNCAYD 518

Query: 1931 ----RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHNCNHRED 1980
                R  ++  +   G   G    +D+    T +TLW         N+  F+ N    ED
Sbjct: 519  YLEVRDGTSENSPLIGRFCGYDKPEDIR--STSNTLWMKFVSDGTVNKAGFAANFFKEED 576

Query: 1981 AGVI-----CSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2026
                     C    L+T         P   L   R + + +CGG L++ +G  ++P +P 
Sbjct: 577  ECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPK 636

Query: 2027 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDG- 2083
             YP N  CVW +     YR++V F   +LEG   C YDY+E++ G    S L  + C   
Sbjct: 637  EYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAE 696

Query: 2084 ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYS 2116
                 TS  N M I F SD++++++GF+A ++S
Sbjct: 697  VPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFS 729



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 1/114 (0%)

Query: 1764 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
            + C   +   SG  +SP++P  YP+  +C WEI    G+RI L FS  ++E H  C++D+
Sbjct: 772  AECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDH 831

Query: 1824 VEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
            +E+FDG    S +LG++C N       ++ N+M + F SD S Q  GF A +++
Sbjct: 832  LEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHST 885



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 38/110 (34%), Positives = 64/110 (58%), Gaps = 3/110 (2%)

Query: 2008 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 2065
            C   +  PSG  +SP +P  YP+  +C W+I     +R+ + F + ++E    C YD++E
Sbjct: 774  CEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLE 833

Query: 2066 VFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
            VFDG    SP++ R+C +       ++ N M +RF+SD S+ R+GF+A +
Sbjct: 834  VFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATH 883



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 41/111 (36%), Positives = 59/111 (53%), Gaps = 3/111 (2%)

Query: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIF--RDVQLEGGCNYDYI 2064
            +CG  L + +G+ SSP +P  YP+   C+W + V    ++ + F   D+     C YDYI
Sbjct: 348  ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYI 407

Query: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
            EV DG +R SPL+ R C D      TS+ + M I F S  +   +GF A Y
Sbjct: 408  EVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 7/123 (5%)

Query: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
            A  S+ CGG L   S      S+  +    YP    C W +    G R+ L F   ++E 
Sbjct: 881  ATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEE 940

Query: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1873
              +C +DYVE+FDG  ++++ LG+ C      +I+ S  + + IHF +D +    GF   
Sbjct: 941  EADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIY-SIGDSVLIHFHTDDTINKKGFHIR 999

Query: 1874 YNS 1876
            Y S
Sbjct: 1000 YKS 1002



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 39/124 (31%), Positives = 62/124 (50%), Gaps = 7/124 (5%)

Query: 2008 CGGFL---SQPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 2061
            CGG L   S+P   +S + F   NYP    C W +  +   R+ + F+  +V+ E  C Y
Sbjct: 887  CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGY 946

Query: 2062 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 2120
            DY+E+FDG   ++  + R C  G      S  + + I F +D +I ++GF   Y S    
Sbjct: 947  DYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIRYP 1006

Query: 2121 DSTN 2124
            D+T+
Sbjct: 1007 DTTH 1010


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score =  144 bits (364), Expect = 8e-34
 Identities = 115/391 (29%), Positives = 171/391 (43%), Gaps = 50/391 (12%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CG  L   +G FS+P +P  YP+ + CVW I V  G +I L F+++ L     C +DYVE
Sbjct: 351  CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410

Query: 1826 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS-----FPS 1879
            + DG    + LLG+ C D   +   S+ +R+ + FRS  +    GF A Y +        
Sbjct: 411  VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMNK 470

Query: 1880 DA-TLRLVNLNSSYGL---CAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCG----- 1930
            DA  ++  N    Y     C  R+ +  G   G       T Q  E+  R   C      
Sbjct: 471  DAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGL------TFQAFEIE-RHDSCAYDYLE 523

Query: 1931 -RAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN--------- 1974
             R      +A  G   G    +DV+ S     LW         N+  F+ N         
Sbjct: 524  VRDGPTEESALIGHFCGYEKPEDVKSSSNR--LWMKFVSDGSINKAGFAANFFKEVDECS 581

Query: 1975 ------CNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNY 2028
                  C HR     + S      P   L   +   + +CGGF+++ +G  +SP +P  Y
Sbjct: 582  WPDHGGCEHR-CVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640

Query: 2029 PNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARG 2086
            P N  CVW +     YR+++ F   +LEG   C YD++EV  G    + L  R C     
Sbjct: 641  PTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGSETP 700

Query: 2087 S-FTSSSNFMSIRFISDHSITRRGFRAEYYS 2116
               TS SN M + F SD+++++RGFRA ++S
Sbjct: 701  EVITSQSNNMRVEFKSDNTVSKRGFRAHFFS 731



 Score = 94.0 bits (232), Expect = 2e-18
 Identities = 51/172 (29%), Positives = 86/172 (50%), Gaps = 9/172 (5%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CGGF+   +GT +SP +P  YP N  CVW++   + YRI+L F   +LE +  C +D+VE
Sbjct: 620  CGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVE 679

Query: 1826 IFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1884
            +  G    + L G+ C ++T ++ TS  N M + F+SD +    GF A + S   +    
Sbjct: 680  VRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECA-- 737

Query: 1885 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSAL 1936
                    G C     +   G++   C + + + E    C++ GC   +S++
Sbjct: 738  -----KDNGGCQHEC-VNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSV 783



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 9/182 (4%)

Query: 1764 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
            + CGG +   +G   SP+YP  Y  + +CVW I V+ G+ + L F   ++E H +C++DY
Sbjct: 462  ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDY 521

Query: 1824 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1882
            +E+ DG    S L+G  C  +  +   SS NR+ + F SD S    GF A +     + +
Sbjct: 522  LEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECS 581

Query: 1883 LRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG 1942
                     +G C  R  +   G++   CD  + +   + +C ++ CG  ++ L      
Sbjct: 582  W------PDHGGCEHRC-VNTLGSYKCACDPGYELAADKKMC-EVACGGFITKLNGTITS 633

Query: 1943 SG 1944
             G
Sbjct: 634  PG 635



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 29/163 (17%)

Query: 1954 ECSGT-ESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFL 2012
            EC  T  S L +CRN  W   N +  ++AG                         C   +
Sbjct: 746  ECVNTFGSYLCRCRNGYWLHENGHDCKEAG-------------------------CAHKI 780

Query: 2013 SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGP 2070
            S   G  +SP +P  YP+  +C W+I     +RV + F + ++E    C YD++E++DGP
Sbjct: 781  SSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGP 840

Query: 2071 YRSSPLIARVCDGARGSFT-SSSNFMSIRFISDHSITRRGFRA 2112
               +P++ R C   +   T +S + M +RF SD S+ R+GF+A
Sbjct: 841  DSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 36/114 (31%), Positives = 66/114 (57%), Gaps = 1/114 (0%)

Query: 1764 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
            + C   +    GT +SP++P  YP+  +C W I   +G+R+ L F+  ++E H  C++D+
Sbjct: 774  AGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDH 833

Query: 1824 VEIFDGSLNSSLLLGKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNS 1876
            +E++DG  + + +LG+ C   +   T +S + M + F SD S Q  GF A +++
Sbjct: 834  LEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHST 887



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 44/125 (35%), Positives = 68/125 (54%), Gaps = 7/125 (5%)

Query: 2008 CGGFLS---QPSGDFS-SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNY 2061
            CGG L    Q    +S + F   NYP+ A+C W I  ++ Y V + FR  +V+ E  C Y
Sbjct: 889  CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGY 948

Query: 2062 DYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSN 2120
            DY+E +DG   S+P + R C  G      S+ + + IRF +D +I ++GF A Y S+   
Sbjct: 949  DYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTKFQ 1008

Query: 2121 DSTNL 2125
            D+ ++
Sbjct: 1009 DALHM 1013



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 40/118 (33%), Positives = 63/118 (53%), Gaps = 3/118 (2%)

Query: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 2064
            +CG  L   +G+FS+P +P  YP+ + CVW I V    ++ + F  + L     C YDY+
Sbjct: 350  ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYV 409

Query: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSND 2121
            EV DG +R +PL+ R C D       S+ + + + F S  +I  +GF A Y ++   D
Sbjct: 410  EVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGD 467



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 7/120 (5%)

Query: 1763 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 1818
            S+ CGG L     T    S+  +    YP+ A+C W I    GY + L F   ++E   +
Sbjct: 886  STECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD 945

Query: 1819 CSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
            C +DY+E +DG  +S+  LG+ C      +I+ S+ + + I FR+D +    GF A Y S
Sbjct: 946  CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIY-SAGDSLMIRFRTDDTINKKGFHARYTS 1004


>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
            sapiens]
          Length = 730

 Score =  138 bits (348), Expect = 6e-32
 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CG  L  ++G FSSP YP  Y  +  CVW I V  G +I L F++L L     C +DYVE
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 1826 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1882
            + DG    + L G+ C     +   S+ +R+ + FRS  ++   GF A Y +        
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441

Query: 1883 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1935
                ++  N    Y    +C  R+++  G   G     S+ I+  +         R   +
Sbjct: 442  DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500

Query: 1936 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1982
              +   G   G    DD++   T S LW         N+  F+ N       C+     G
Sbjct: 501  ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558

Query: 1983 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 2033
              C    L+T         P   L   +   + +CGGFL++ +G  +SP +P  YP N  
Sbjct: 559  --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616

Query: 2034 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 2090
            C+W +     YR+++ F   + EG   C YD++EV  G    S L  + C   +    TS
Sbjct: 617  CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676

Query: 2091 SSNFMSIRFISDHSITRRGFRAEYYS 2116
              N M + F SD++++++GF+A ++S
Sbjct: 677  QYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 43/117 (36%), Positives = 65/117 (55%), Gaps = 1/117 (0%)

Query: 1761 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1820
            R  + CGGFL   +G+ +SP +P  YP N  C+W++   + YRI+L F   + E +  C 
Sbjct: 586  RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645

Query: 1821 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
            +D+VE+  G    S L GK C   + ++ TS YN M + F+SD +    GF A + S
Sbjct: 646  YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%)

Query: 2008 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 2065
            CGG + +  G   SP YP +Y  +  C+W I+V   + V + F+  ++E    C YDY+E
Sbjct: 435  CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494

Query: 2066 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 2118
            V DG   SS LI R C   +     S+S+ + ++F+SD SI + GF   ++      S P
Sbjct: 495  VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554

Query: 2119 SNDSTNLLCL 2128
            +       CL
Sbjct: 555  NRGGCEQRCL 564



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 2064
            +CG  L   +G+FSSP YP  Y  +  CVW I V    ++ + F  + L     C YDY+
Sbjct: 321  ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 2065 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 2114
            EV DG +R +PL  R C         S+ + + + F S  +   +GF A Y
Sbjct: 381  EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
            sapiens]
          Length = 823

 Score =  138 bits (348), Expect = 6e-32
 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CG  L  ++G FSSP YP  Y  +  CVW I V  G +I L F++L L     C +DYVE
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 1826 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1882
            + DG    + L G+ C     +   S+ +R+ + FRS  ++   GF A Y +        
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441

Query: 1883 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1935
                ++  N    Y    +C  R+++  G   G     S+ I+  +         R   +
Sbjct: 442  DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500

Query: 1936 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1982
              +   G   G    DD++   T S LW         N+  F+ N       C+     G
Sbjct: 501  ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558

Query: 1983 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 2033
              C    L+T         P   L   +   + +CGGFL++ +G  +SP +P  YP N  
Sbjct: 559  --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616

Query: 2034 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 2090
            C+W +     YR+++ F   + EG   C YD++EV  G    S L  + C   +    TS
Sbjct: 617  CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676

Query: 2091 SSNFMSIRFISDHSITRRGFRAEYYS 2116
              N M + F SD++++++GF+A ++S
Sbjct: 677  QYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 43/117 (36%), Positives = 65/117 (55%), Gaps = 1/117 (0%)

Query: 1761 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1820
            R  + CGGFL   +G+ +SP +P  YP N  C+W++   + YRI+L F   + E +  C 
Sbjct: 586  RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645

Query: 1821 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
            +D+VE+  G    S L GK C   + ++ TS YN M + F+SD +    GF A + S
Sbjct: 646  YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%)

Query: 2008 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 2065
            CGG + +  G   SP YP +Y  +  C+W I+V   + V + F+  ++E    C YDY+E
Sbjct: 435  CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494

Query: 2066 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 2118
            V DG   SS LI R C   +     S+S+ + ++F+SD SI + GF   ++      S P
Sbjct: 495  VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554

Query: 2119 SNDSTNLLCL 2128
            +       CL
Sbjct: 555  NRGGCEQRCL 564



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 2064
            +CG  L   +G+FSSP YP  Y  +  CVW I V    ++ + F  + L     C YDY+
Sbjct: 321  ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 2065 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 2114
            EV DG +R +PL  R C         S+ + + + F S  +   +GF A Y
Sbjct: 381  EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
            sapiens]
          Length = 986

 Score =  138 bits (348), Expect = 6e-32
 Identities = 107/386 (27%), Positives = 170/386 (44%), Gaps = 40/386 (10%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CG  L  ++G FSSP YP  Y  +  CVW I V  G +I L F++L L     C +DYVE
Sbjct: 322  CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381

Query: 1826 IFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT-- 1882
            + DG    + L G+ C     +   S+ +R+ + FRS  ++   GF A Y +        
Sbjct: 382  VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKK 441

Query: 1883 ----LRLVNLNSSYG---LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSA 1935
                ++  N    Y    +C  R+++  G   G     S+ I+  +         R   +
Sbjct: 442  DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ-SFEIERHDSCAYDYLEVRDGHS 500

Query: 1936 LGNAYFGSGSGPITLDDVECSGTESTLWQ------CRNRGWFSHN-------CNHREDAG 1982
              +   G   G    DD++   T S LW         N+  F+ N       C+     G
Sbjct: 501  ESSTLIGRYCGYEKPDDIK--STSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG 558

Query: 1983 VICSGNHLST---------PAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAK 2033
              C    L+T         P   L   +   + +CGGFL++ +G  +SP +P  YP N  
Sbjct: 559  --CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKN 616

Query: 2034 CVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGS-FTS 2090
            C+W +     YR+++ F   + EG   C YD++EV  G    S L  + C   +    TS
Sbjct: 617  CIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITS 676

Query: 2091 SSNFMSIRFISDHSITRRGFRAEYYS 2116
              N M + F SD++++++GF+A ++S
Sbjct: 677  QYNNMRVEFKSDNTVSKKGFKAHFFS 702



 Score =  104 bits (260), Expect = 9e-22
 Identities = 87/356 (24%), Positives = 144/356 (40%), Gaps = 87/356 (24%)

Query: 1761 RPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCS 1820
            R  + CGGFL   +G+ +SP +P  YP N  C+W++   + YRI+L F   + E +  C 
Sbjct: 586  RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645

Query: 1821 FDYVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPS 1879
            +D+VE+  G    S L GK C   + ++ TS YN M + F+SD +    GF A + S   
Sbjct: 646  YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKD 705

Query: 1880 DATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA 1939
            + +        + G     V  +  G++   C   + + + +  C++ GC   V+     
Sbjct: 706  ECS------KDNGGCQQDCVNTF--GSYECQCRSGFVLHDNKHDCKEAGCDHKVT----- 752

Query: 1940 YFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNI 1999
               S SG IT                      S N   +  +   C+    STP   + +
Sbjct: 753  ---STSGTIT----------------------SPNWPDKYPSKKECTWAISSTPGHRVKL 787

Query: 2000 TRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGC 2059
            T    D       SQP                 +C +D                      
Sbjct: 788  TFMEMDIE-----SQP-----------------ECAYD---------------------- 803

Query: 2060 NYDYIEVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 2114
               ++EVFDG    +P++ R C   +     ++ + M +RF SD+S+ R+GF+A +
Sbjct: 804  ---HLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 43/130 (33%), Positives = 66/130 (50%), Gaps = 9/130 (6%)

Query: 2008 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 2065
            CGG + +  G   SP YP +Y  +  C+W I+V   + V + F+  ++E    C YDY+E
Sbjct: 435  CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494

Query: 2066 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYY------SSP 2118
            V DG   SS LI R C   +     S+S+ + ++F+SD SI + GF   ++      S P
Sbjct: 495  VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554

Query: 2119 SNDSTNLLCL 2128
            +       CL
Sbjct: 555  NRGGCEQRCL 564



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 52/199 (26%), Positives = 89/199 (44%), Gaps = 15/199 (7%)

Query: 1764 SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
            + C   +   SGT +SP++P  YP+  +C W I    G+R+ L F  + +E+   C++D+
Sbjct: 745  AGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDH 804

Query: 1824 VEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1882
            +E+FDG    + +LG+ C   + +   ++ +RM + F SD S Q  GF A + +      
Sbjct: 805  LEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQV 864

Query: 1883 LRLVNLNSSYGLCAGRVEIYHGGT---WGTVCDDSWTIQ---EAEVVCRQLGCGRAVSAL 1936
               V     Y         Y GG    W  V ++ + ++   +   V  +  CG     L
Sbjct: 865  RADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMEL 924

Query: 1937 GNAYFGS--------GSGP 1947
             + Y  +        GSGP
Sbjct: 925  FDGYDSTAPRLGRYCGSGP 943



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 35/103 (33%), Positives = 56/103 (54%), Gaps = 3/103 (2%)

Query: 2023 FYPGNYPNNAKCVWDIEVQNNYRVTVIFR--DVQLEGGCNYDYIEVFDGPYRSSPLIARV 2080
            F   NYP    C W I  +  Y V ++F+  +V+ E  C YDY+E+FDG   ++P + R 
Sbjct: 879  FGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRY 938

Query: 2081 C-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPSNDS 2122
            C  G      S+ + + ++F SD +IT++GF   Y S+   D+
Sbjct: 939  CGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDT 981



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)

Query: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYI 2064
            +CG  L   +G+FSSP YP  Y  +  CVW I V    ++ + F  + L     C YDY+
Sbjct: 321  ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYV 380

Query: 2065 EVFDGPYRSSPLIARVCDGARGS-FTSSSNFMSIRFISDHSITRRGFRAEY 2114
            EV DG +R +PL  R C         S+ + + + F S  +   +GF A Y
Sbjct: 381  EVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431


>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
          Length = 449

 Score =  136 bits (342), Expect = 3e-31
 Identities = 115/377 (30%), Positives = 156/377 (41%), Gaps = 40/377 (10%)

Query: 1754 PTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKL 1813
            P     A     CGG L   SG FSSP++P  YP N +C W I V  G  + L F    L
Sbjct: 18   PGLQAQAMEGVKCGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDL 77

Query: 1814 EAHHNCSFDYVEIFDG-SLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFL 1871
            E H  CSFD++EI++G S +   LLG+ C       FTSS++ M++ F SD    + GF 
Sbjct: 78   EYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFS 137

Query: 1872 AWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGR 1931
            A Y        L         GL        +   +    +  W I+ A         G 
Sbjct: 138  AGYQKDVCGGVLT--------GLSGVLTSPEYPNNYPNSMECHWVIRAA---------GP 180

Query: 1932 A-VSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1990
            A V  +   +   G+   T D V   G          RG   H C       ++  G+ L
Sbjct: 181  AHVKLVFVDFQVEGNEECTYDYVAVLGGPGP-----TRG--HHYCGSTRPPTLVSLGHEL 233

Query: 1991 ST--PAPFLNITRPNTDY----SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNY 2044
                 + F    R    Y     C        G+FSSP YP +YPNN +C W I +   Y
Sbjct: 234  QVVFKSDFNIGGRGFKAYYFSGECQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGY 293

Query: 2045 RVTVIFRDVQLE------GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSI 2097
            +V V F D+ LE        C++D++  FDG    +PL+   C        TSS N + +
Sbjct: 294  QVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLL 353

Query: 2098 RFISDHSITRRGFRAEY 2114
               +D S TRRGF   Y
Sbjct: 354  LLHTDRSTTRRGFSVAY 370



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 43/112 (38%), Positives = 59/112 (52%), Gaps = 5/112 (4%)

Query: 2008 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIE 2065
            CGG L+  SG  +SP YP NYPN+ +C W I       V ++F D Q+EG   C YDY+ 
Sbjct: 145  CGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVA 204

Query: 2066 VFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEYYS 2116
            V  GP  +       C   R  +  S  + + + F SD +I  RGF+A Y+S
Sbjct: 205  VLGGPGPTRG--HHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFS 254


>gi|5031863 galectin 3 binding protein [Homo sapiens]
          Length = 585

 Score =  134 bits (337), Expect = 1e-30
 Identities = 63/108 (58%), Positives = 78/108 (72%), Gaps = 1/108 (0%)

Query: 602 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661
           +RL +GG   QGRVE+ YRG WGTVCD+ WD  DA+VVCR LG   AT A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 662 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRST 709
           GPI+LD+V+C+G E+ L  C + GWL  NC H  DAGV+C+  ++RST
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT-NETRST 130



 Score =  134 bits (336), Expect = 1e-30
 Identities = 60/101 (59%), Positives = 74/101 (73%)

Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
           +RL +GG   QGRVE+ YRG WGTVCD+ WD +DA+VVCR LG   AT A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
           GPI+LD+V+C+G E+ L  C   GWL  NC+H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  134 bits (336), Expect = 1e-30
 Identities = 60/101 (59%), Positives = 74/101 (73%)

Query: 862 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 921
           +RL +GG   QGRVE+ YRG WGTVCD+ WD +DA+VVCR LG   AT A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 922 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962
           GPI+LD+V+C+G E+ L  C   GWL  NC+H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  132 bits (333), Expect = 3e-30
 Identities = 60/101 (59%), Positives = 72/101 (71%)

Query: 1251 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGS 1310
            +RL +GG   QGRVE+ YRG WGTVCD+ WD  DA+VVCR LG   AT A G A FGQGS
Sbjct: 24   MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 1311 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1351
            GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84   GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  132 bits (333), Expect = 3e-30
 Identities = 60/101 (59%), Positives = 72/101 (71%)

Query: 1380 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGS 1439
            +RL +GG   QGRVE+ YRG WGTVCD+ WD  DA+VVCR LG   AT A G A FGQGS
Sbjct: 24   MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 1440 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
            GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84   GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  131 bits (329), Expect = 9e-30
 Identities = 62/112 (55%), Positives = 78/112 (69%), Gaps = 1/112 (0%)

Query: 733 LRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 792
           +RL +G    QGRVE+ YRG WGTVCD+ WD  DA+VVCR LG   AT A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 793 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTPSPD 844
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+ +++R T + D
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT-NETRSTHTLD 134



 Score =  130 bits (327), Expect = 2e-29
 Identities = 60/111 (54%), Positives = 75/111 (67%)

Query: 1640 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1699
            +RL +GG   +GRVE+ YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24   MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 1700 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTTTD 1750
            GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+    ++ T D
Sbjct: 84   GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLD 134



 Score =  130 bits (327), Expect = 2e-29
 Identities = 60/106 (56%), Positives = 72/106 (67%)

Query: 494 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 553
           +RL +GG   QGRVE+ YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 554 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESS 599
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+    S
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRS 129



 Score =  130 bits (327), Expect = 2e-29
 Identities = 59/101 (58%), Positives = 71/101 (70%)

Query: 1122 LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1181
            +RL +GG   QGRVE+ YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24   MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 1182 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1222
            GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84   GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  129 bits (325), Expect = 3e-29
 Identities = 61/112 (54%), Positives = 78/112 (69%), Gaps = 1/112 (0%)

Query: 993  LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1052
            +RL +GG   QGRVE+ Y+G WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24   MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 1053 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPD 1104
            GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+ +++R T + D
Sbjct: 84   GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT-NETRSTHTLD 134



 Score =  128 bits (322), Expect = 6e-29
 Identities = 58/101 (57%), Positives = 71/101 (70%)

Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
           +RL +GG   +GRVE+ YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  127 bits (319), Expect = 1e-28
 Identities = 57/101 (56%), Positives = 71/101 (70%)

Query: 1509 LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 1568
            +RL +GG   +GRVE+ Y+G WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24   MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 1569 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609
            GPI+LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84   GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  126 bits (316), Expect = 3e-28
 Identities = 59/101 (58%), Positives = 69/101 (68%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           +RL +G    QGRVEI YRG WGTVCD+ WD  DA+VVCR LG   A  A G A FGQGS
Sbjct: 24  MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
           GPI LD+V+C+G E+ L  C   GWL  NC H  DAGV+C+
Sbjct: 84  GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCT 124



 Score =  123 bits (308), Expect = 2e-27
 Identities = 53/96 (55%), Positives = 67/96 (69%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
            GRVEI++ G WGTVCD+ W + +A VVCR LG   A  ALG A FG GSGPI LD+V+C+
Sbjct: 35   GRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCT 94

Query: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLST 1992
            GTE++L  C++ GW   NC H  DAGV+C+    ST
Sbjct: 95   GTEASLADCKSLGWLKSNCRHERDAGVVCTNETRST 130


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score =  125 bits (314), Expect = 5e-28
 Identities = 107/377 (28%), Positives = 162/377 (42%), Gaps = 54/377 (14%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CGG L  A+G+FSSP +P  YP N +C+W I  + G  I L   +  +E H  C+FD +E
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLE 1450

Query: 1826 IFDGSLNSSLLLGKICN----DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1881
            I+ G    S  + ++C     +     +S+ N + I F++D+S    GF A + +     
Sbjct: 1451 IYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVT--- 1507

Query: 1882 TLRLVNLNSSYGLCAGRVEIYHG--------GTWGTVCDDSWTIQEAEVVCRQLGCGRAV 1933
                       G C G  +   G          + +  D SW I+            R  
Sbjct: 1508 -----------GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIR----------VDRNH 1546

Query: 1934 SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAG-VICSGNHL-- 1990
              L N +      P     +   G  ST+ +       +  C   + A  ++ SGN L  
Sbjct: 1547 RVLLN-FTDFDLEPQDSCIMAYDGLSSTMSR------LARTCGREQLANPIVSSGNSLFL 1599

Query: 1991 ---STPAPFLNITRPNTDYSCGGFLSQPSGD-FSSPFYPGNYPNNAKCVWDIEVQNNY-R 2045
               S P+      R     +CGG +   S D  SSP +P NYPNN  C W I+ Q     
Sbjct: 1600 RFQSGPSRQNRGFRAQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNH 1659

Query: 2046 VTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISD 2102
            +T+ F   +LE    C  D++E+ DG +  +PL  R C        TS S+ +++RF+SD
Sbjct: 1660 ITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSD 1719

Query: 2103 HSITRRGFRAEYYSSPS 2119
             SI+  GF     +S S
Sbjct: 1720 SSISAGGFHTTVTASVS 1736



 Score =  125 bits (313), Expect = 7e-28
 Identities = 107/388 (27%), Positives = 168/388 (43%), Gaps = 82/388 (21%)

Query: 1763 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1822
            S+ CGG L  +SGTF SP+YP  Y ++++C W ++ + G    L F +  LE H NC+ D
Sbjct: 1162 STGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLD 1221

Query: 1823 YVEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1881
            Y+ ++DG  ++S LL ++C D +  +  SS + M I  R+D   Q  GF A Y       
Sbjct: 1222 YLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR----QT 1277

Query: 1882 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQ----------------EAEVVC- 1924
               +V +N +YG+      I +   +      +WTI+                E  + C 
Sbjct: 1278 CENVVIVNQTYGILE---SIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCS 1334

Query: 1925 ----------RQLG--CGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFS 1972
                      RQ+G  CG  +   G+         +  D V   G     +Q +   WF 
Sbjct: 1335 TDYLELYDGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGV---GRREKGFQMQ---WFV 1388

Query: 1973 HNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNA 2032
            + C           G  LS               + G F S        P +P  YP N 
Sbjct: 1389 YGC-----------GGELSG--------------ATGSFSS--------PGFPNRYPPNK 1415

Query: 2033 KCVWDIEVQ--NNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARG---- 2086
            +C+W I     ++ ++T+   DV+    CN+D +E++ GP   SP IA++C         
Sbjct: 1416 ECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPM 1475

Query: 2087 SFTSSSNFMSIRFISDHSITRRGFRAEY 2114
              +S+ N ++IRF +D SI  RGF A +
Sbjct: 1476 QVSSTGNELAIRFKTDLSINGRGFNASW 1503



 Score =  124 bits (312), Expect = 9e-28
 Identities = 102/368 (27%), Positives = 158/368 (42%), Gaps = 32/368 (8%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CG  L  ++GT  SP +P  YP+   C W I V   + I+L F    LE H+NC+ DY+E
Sbjct: 932  CGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991

Query: 1826 IFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1884
            ++D   +S   LG+ C  +     TSS N + + F +D      GFL  Y +  S AT  
Sbjct: 992  VYD--TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI-SAATAC 1048

Query: 1885 LVNLNSSYG-LCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF-- 1941
            L +     G   +      +   W   C    T++  +++           A+GN Y   
Sbjct: 1049 LQDYTDDLGTFTSPNFPNNYPNNW--ECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDF 1106

Query: 1942 ------GSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAP 1995
                  G    P+ L     S    T+    N+ W                 + + T + 
Sbjct: 1107 LEIRDGGYEKSPL-LGIFYGSNLPPTIISHSNKLWLKF------------KSDQIDTRSG 1153

Query: 1996 FLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQL 2055
            F +     +   CGG L+  SG F SP YP  Y ++++C W ++  +     + F+D  L
Sbjct: 1154 F-SAYWDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHL 1212

Query: 2056 E--GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRA 2112
            E    C  DY+ V+DGP  +S L+ ++C D       SS + M I+  +D     RGF+A
Sbjct: 1213 EHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKA 1272

Query: 2113 EYYSSPSN 2120
            EY  +  N
Sbjct: 1273 EYRQTCEN 1280



 Score =  122 bits (307), Expect = 3e-27
 Identities = 112/398 (28%), Positives = 169/398 (42%), Gaps = 71/398 (17%)

Query: 1756 TTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
            TT TA  S+ CGG  + A G F+SP YP  YP N +CVW I  + G R+ L F + +LE 
Sbjct: 1729 TTVTASVSA-CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLED 1787

Query: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICNDTRQIFTSSY--NRMTIHFRSDISFQNTGFLA- 1872
              +CS D+VEI +G+     L+G+ C ++  +  SS   + + + F SD S   TGF A 
Sbjct: 1788 SQDCSRDFVEIREGNATGH-LVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQAT 1846

Query: 1873 ---------------------WYNSFPSDATLR-LVNLNSSYGLCAGRVEIYHGGTWGTV 1910
                                 W  ++P ++  +  VN+N+S+ +    +E+         
Sbjct: 1847 FMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCY 1906

Query: 1911 CDDSWTIQEAEVVCRQLG--CGRAVSALGNAYFGSGSGPITL---DDVECSGTESTLWQC 1965
             D         +  R +G  CG    +     F S    +T     D   SG    L   
Sbjct: 1907 YDKLRIYDGPSIHARLIGAYCGTQTES-----FSSTGNSLTFHFYSDSSISGKGFLL--- 1958

Query: 1966 RNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGD----FSS 2021
                WF+          V      L T AP           +CGGFL   +GD      S
Sbjct: 1959 ---EWFA----------VDAPDGVLPTIAP----------GACGGFLR--TGDAPVFLFS 1993

Query: 2022 PFYPGNYPNNAKCVWDIEV-QNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARV 2080
            P +P +Y N   C W I+   +   + ++  D++    C YD + + DG    +  +A +
Sbjct: 1994 PGWPDSYSNRVDCTWLIQAPDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLAVL 2053

Query: 2081 CD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSS 2117
            C     G   S+  +M IRF SD S+TR GF A ++ S
Sbjct: 2054 CGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKS 2091



 Score =  113 bits (283), Expect = 2e-24
 Identities = 104/396 (26%), Positives = 163/396 (41%), Gaps = 58/396 (14%)

Query: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
            G  +SP +P  YP+N+   W + VN+ + ++     + +E   NC +D + I+DG    +
Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHA 1920

Query: 1835 LLLGKICNDTRQIFTSSYNRMTIHFRSDISFQNTGFLA-WYNSFPSDATLRLVNLNSSYG 1893
             L+G  C    + F+S+ N +T HF SD S    GFL  W+     D  L  +    + G
Sbjct: 1921 RLIGAYCGTQTESFSSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTI----APG 1976

Query: 1894 LCAG-------RVEIYHGG---TWGTVCDDSWTIQ------EAEVVCRQLGCGRAVSALG 1937
             C G        V ++  G   ++    D +W IQ      E  ++   +   R   A  
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDSTVELNILSLDIESHRTC-AYD 2035

Query: 1938 NAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFL 1997
            +     G   +        G E      R+ G +        D+ V  +G + S      
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIP-GPIRSTGEYMF-IRFTSDSSVTRAGFNASFHK--- 2090

Query: 1998 NITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIF-RDVQLE 2056
                     SCGG+L    G  +SP YP  YP+N  C W + VQ+   + V F +  Q+ 
Sbjct: 2091 ---------SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIP 2141

Query: 2057 GG---CNY-DYIEVFDGPYRSSPLI------ARVCDG-ARGSFTSSSNFMSIRFISDHSI 2105
             G   CN  DY+ + +GP   SP +         C   A  +  +S N M ++FISDHS 
Sbjct: 2142 NGDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSN 2201

Query: 2106 TRRGFRAEYYSSP----------SNDSTNLLCLPNH 2131
              +GF+ +Y +              DS   +  PNH
Sbjct: 2202 EGQGFKIKYEAKSLACGGNVYIHDADSAGYVTSPNH 2237



 Score =  112 bits (279), Expect = 6e-24
 Identities = 103/382 (26%), Positives = 161/382 (42%), Gaps = 60/382 (15%)

Query: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYR-INLGFSNLKLEAHHNCSFDY 1823
            CGG +  +S  T SSP +PA YPNN  C W I+       I L F++ +LE    C+ D+
Sbjct: 1620 CGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDF 1679

Query: 1824 VEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDAT 1882
            VEI DG    + L G+ C  D     TS  + +T+ F SD S    G       F +  T
Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGG-------FHTTVT 1732

Query: 1883 LRLVNLNSSYGLCAGRV------EIYHGGT---WGTVCDD---------SWTIQEAEVVC 1924
              +     ++ +  G        +IY       W  V            S+ +++++   
Sbjct: 1733 ASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCS 1792

Query: 1925 R---QLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDA 1981
            R   ++  G A   L   Y G+ S P+    +       TLW                D 
Sbjct: 1793 RDFVEIREGNATGHLVGRYCGN-SFPLNYSSI----VGHTLW-----------VRFISDG 1836

Query: 1982 GVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQ 2041
                SG+     A F+ I     D   G       G  +SPF+P NYP+N+   W + V 
Sbjct: 1837 ----SGSGTGFQATFMKIF--GNDNIVG-----THGKVASPFWPENYPHNSNYQWTVNVN 1885

Query: 2042 NNYRV--TVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSFTSSSNFMSIRF 2099
             ++ V   ++  D++    C YD + ++DGP   + LI   C     SF+S+ N ++  F
Sbjct: 1886 ASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIHARLIGAYCGTQTESFSSTGNSLTFHF 1945

Query: 2100 ISDHSITRRGFRAEYYSSPSND 2121
             SD SI+ +GF  E+++  + D
Sbjct: 1946 YSDSSISGKGFLLEWFAVDAPD 1967



 Score =  106 bits (265), Expect = 2e-22
 Identities = 103/398 (25%), Positives = 163/398 (40%), Gaps = 53/398 (13%)

Query: 1748 TTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPA--YYPNNAKCVWEIEVNSGYRIN 1805
            T   W  +   T  P   CGG+L  ++ TF+SP   +   Y  N  CVW I       I+
Sbjct: 3139 TAKGWKMSFRQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIH 3198

Query: 1806 LGFSNLKLEA---HHNCSFDYVEIFDGSLNSSLLLGKICNDTRQI-FTSSYNRMTIHFRS 1861
            L F+   LEA      C +DYV+++DG   ++ L G  C  T    F SS N +T+ F S
Sbjct: 3199 LTFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFIS 3258

Query: 1862 DISFQNTGFLAWYNSFPS------DATLRLVNLNS--------SYGLCAGRVEI-YHGGT 1906
            D++ +  GF A Y           +AT    N++S         + +C   ++   H   
Sbjct: 3259 DLTLEREGFNATYTIMDMPCGGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQV 3318

Query: 1907 WGTVCDDSWTIQEAEVVCRQ--LGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQ 1964
              TV    W +Q     C Q  L    +    GN+ F       +   V  S   + +  
Sbjct: 3319 KITV----WALQLTSQDCTQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVI 3374

Query: 1965 CRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFY 2024
             +              +GV+   + +S       I   N DY       +  G+  SP +
Sbjct: 3375 FK--------------SGVVNRNSRMSFT---YQIADCNRDY------HKAFGNLRSPGW 3411

Query: 2025 PGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCD 2082
            P NY N+  C   +    N+ +++ F  + +E    C  D++EV +G   +SPL+ + C 
Sbjct: 3412 PDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCG 3471

Query: 2083 G-ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYSSPS 2119
                    S +N + +RF SD   + RG+   + SSPS
Sbjct: 3472 TLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPS 3509



 Score =  104 bits (260), Expect = 9e-22
 Identities = 109/416 (26%), Positives = 164/416 (39%), Gaps = 49/416 (11%)

Query: 1727 HNCGHHEDAGVICSATQIN----STTTDWWHPTTTTTARPSSNCGGFLFY----ASGTFS 1778
            H CG H  + +  S  Q+     S  ++            S  CGG ++     ++G  +
Sbjct: 2174 HFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGNVYIHDADSAGYVT 2233

Query: 1779 SPSYPAYYPNNAKCVWEIEVNSGYRINLGFSN-LKLEAHHNCSFDYVEIFDGSLNSSLLL 1837
            SP++P  YP +A C+W +      RI L F +   +E   NC+ +Y+E+ DG  + + +L
Sbjct: 2234 SPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPIL 2293

Query: 1838 GKICNDTRQIFT-SSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCA 1896
             K C  +      SS   M + FRSD S  + GF A Y                S   C 
Sbjct: 2294 SKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY----------------SIAQCG 2337

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCR-QLGCGRAVSALGNAYFGSGSGPITLDDVE- 1954
            GRV     G  G V     +I    +  R  L C   +  L   Y         L +   
Sbjct: 2338 GRVP----GQSGVV----ESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSG 2389

Query: 1955 CSGTESTLWQCRNRG-WFSHNCNHREDAGVICSGNHL--------STPAPFLNITRPNTD 2005
            C      +W     G      C +     +  S N          S  A    +   ++ 
Sbjct: 2390 CEKDFVEIWDNHTSGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSM 2449

Query: 2006 YSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCNYDY 2063
              CGG L    G F+SP YP   P+   C W I      R+T++F +++L     CN ++
Sbjct: 2450 EECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEH 2509

Query: 2064 IEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFISDHSITRRGFRAEYYSS 2117
            + VF+G   +SP + ++C     S    SS N M + F +D S    GF A Y SS
Sbjct: 2510 VIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSS 2565



 Score =  103 bits (256), Expect = 3e-21
 Identities = 170/757 (22%), Positives = 268/757 (35%), Gaps = 130/757 (17%)

Query: 1464 WLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGS--ESTLALRLVNGGDRCRGR 1521
            W +H  G+    G  C  +      +       R  T GS   S   LR  +  + C G 
Sbjct: 2398 WDNHTSGNI--LGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGD 2455

Query: 1522 VEVLYQGSWGTVCD-DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDDVRCSG 1580
            +    QGS GT    +Y + N    +C      W ++AP   +       ++ +++R + 
Sbjct: 2456 L----QGSIGTFTSPNYPNPNPHGRICE-----WRITAPEGRRI-----TLMFNNLRLAT 2501

Query: 1581 HESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSESSLAL 1640
            H S                 + +  ++ +  +S S        + N+      S +++ +
Sbjct: 2502 HPSC----------------NNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKV 2545

Query: 1641 RLVNGGDRCRGRVEVLYRGSWGTVCDDSW-DTNDANVVC----------RQLGCGWAMSA 1689
                 G R  G     Y  S   VC  S  +T + N             R L C W +S 
Sbjct: 2546 IFFTDGSRPYGGFTASYTSSEDAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSN 2605

Query: 1690 PGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGV--ICSATQ---- 1743
            P     G  S  I  +D     ++   +       L    G  +   +  +C  ++    
Sbjct: 2606 PNQ---GNSSISIHFEDFYLESHQDCQFDV-----LEFRVGDADGPLMWRLCGPSKPTLP 2657

Query: 1744 -INSTTTDWWHPTTTTTAR--------PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVW 1794
             +   +  W H  T               ++CGG     SG  +SP+YP  Y +   C  
Sbjct: 2658 LVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGGIQIGDSGVITSPNYPNAYDSLTHCSS 2717

Query: 1795 EIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC-NDTRQIFTSSYN 1853
             +E   G+ I L FS+  +E H  C++D V + +G    S ++G+ C N   +   S  N
Sbjct: 2718 LLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSN 2777

Query: 1854 RMTIHFRSDISFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDD 1913
            ++ + F SD S Q  GF A +N+     TL           C G   I+H    GT+   
Sbjct: 2778 QLVVTFNSDHSLQGGGFYATWNT----QTLG----------CGG---IFHSDN-GTIRSP 2819

Query: 1914 SWTIQEAE------VVCRQLGCGRAVSALGNAYFGSGSGPITLDDVEC-SGTESTLWQCR 1966
             W     E                 +S   N    SG G      V+  +GTE       
Sbjct: 2820 HWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTEEV----- 2874

Query: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYS------CGGFLSQPSGDFS 2020
            ++   +  C +     VI   N  +  A F +   P   +S      CG   + PSG   
Sbjct: 2875 DKALLATGCGNVAPGPVITPSNTFT--AVFQSQEAPAQGFSASFVSRCGSNFTGPSGYII 2932

Query: 2021 SPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE------GGCNYDYIEVFDGPYRSS 2074
            SP YP  Y NN  C + IE      V + F    LE      G C  D + +  G    S
Sbjct: 2933 SPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVMS 2992

Query: 2075 PLIARVCDGARGSFTSSSNFMSIRFISDHSITRRGFRAEY----YSSPSNDSTNLLCLPN 2130
               A VC     +  + +  + + F S+  IT  GF+  Y         N S+ ++  P 
Sbjct: 2993 TPFATVCGDEMPAPLTIAGPVLLNFYSNEQITDFGFKFSYRIISCGGVFNFSSGIITSPA 3052

Query: 2131 HMQA------------SVSRSYLQSLGFSASDLVIST 2155
            +  A            +VS   +  L FS  D+V ST
Sbjct: 3053 YSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPST 3089



 Score =  102 bits (255), Expect = 3e-21
 Identities = 104/391 (26%), Positives = 141/391 (36%), Gaps = 57/391 (14%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CGG L    G+  SP YP  YP    CVW +  +    +   F  L LE H +C+ DY+E
Sbjct: 590  CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLE 649

Query: 1826 IFDGSLNSSLLLGKICNDTRQI----FTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDA 1881
            I DG L    LLGK C  T  +     T  + R  IHF SD    + GF   Y + PSD 
Sbjct: 650  IRDGPLYQDPLLGKFCT-TFSVPPLQTTGPFAR--IHFHSDSQISDQGFHITYLTSPSDL 706

Query: 1882 TLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV-------- 1933
                         C G      G  +       +T     V   +   G  +        
Sbjct: 707  R------------CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVE 754

Query: 1934 ----SALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNH 1989
                S     Y     G   L  V  +GT S +    N  W       + DA V      
Sbjct: 755  LQCQSDSSQNYIEVRDGETLLGKVCGNGTISHIKSITNSVWI----RFKIDASV------ 804

Query: 1990 LSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVI 2049
                A F    R     +CG  L+   G   SPF+P  YP    C W I    +  + + 
Sbjct: 805  --EKASF----RAVYQVACGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLN 857

Query: 2050 FR--DVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGARGSF-TSSSNFMSIRFISDHSIT 2106
            F   ++     C  DY+E+       SP   + C     SF TS  NF+ + F+   S  
Sbjct: 858  FTVFEIGSSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTE 917

Query: 2107 RRGFRAEYYSSP------SNDSTNLLCLPNH 2131
              GF A++ +          +ST  +  P H
Sbjct: 918  NHGFMAKFSAEDLACGEILTESTGTIQSPGH 948



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 99/383 (25%), Positives = 156/383 (40%), Gaps = 57/383 (14%)

Query: 1763 SSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFD 1822
            +  CGG     SG   SP+YP+ Y +N  C W I V+  +R+ L F++  LE   +C   
Sbjct: 1507 TGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSCIMA 1566

Query: 1823 YVEIFDGSLNSSLLLGKICNDTRQI--FTSSYNRMTIHFRSDISFQNTGFLAWY------ 1874
            Y    DG  ++   L + C   +      SS N + + F+S  S QN GF A +      
Sbjct: 1567 Y----DGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGG 1622

Query: 1875 ----NSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQ---- 1926
                +SF + ++ R      +   C+  ++        T+    + ++ +    R     
Sbjct: 1623 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1682

Query: 1927 LGCGRAVSALGNAYFGSGSG-PITLDDVECSGTESTLWQCRNRGWFSHNCNHR--EDAGV 1983
            L  G   + L   Y G+    PIT                     FS     R   D+ +
Sbjct: 1683 LDGGHEDAPLRGRYCGTDMPHPITS--------------------FSSALTLRFVSDSSI 1722

Query: 1984 ICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNN 2043
               G H +  A            +CGG      G F+SP YP  YP N +CVW+I     
Sbjct: 1723 SAGGFHTTVTASVS---------ACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPG 1773

Query: 2044 YRVTVIFRDVQLEGG--CNYDYIEVFDGPYRSSPLIARVCDGARGSFTSS--SNFMSIRF 2099
             R+ + F   QLE    C+ D++E+ +G   +  L+ R C  +     SS   + + +RF
Sbjct: 1774 NRLQLSFISFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRF 1832

Query: 2100 ISDHSITRRGFRAEYYSSPSNDS 2122
            ISD S +  GF+A +     ND+
Sbjct: 1833 ISDGSGSGTGFQATFMKIFGNDN 1855



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 107/435 (24%), Positives = 168/435 (38%), Gaps = 54/435 (12%)

Query: 1745 NSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1804
            +S  +D     T  T+     CGG      G    P     + +  +CV+ ++   G +I
Sbjct: 687  DSQISDQGFHITYLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQI 746

Query: 1805 NLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDI 1863
             + F++++L+   + S +Y+E+ DG      LLGK+C N T     S  N + I F+ D 
Sbjct: 747  QINFTHVELQCQSDSSQNYIEVRDGET----LLGKVCGNGTISHIKSITNSVWIRFKIDA 802

Query: 1864 SFQNTGFLAWYNSFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVV 1923
            S +   F A Y     D       + S +        +Y G      C   WTI + +  
Sbjct: 803  SVEKASFRAVYQVACGDELTGEGVIRSPFF-----PNVYPGER---TC--RWTIHQPQ-- 850

Query: 1924 CRQLGCGRAVSALGNAYFGSGSGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGV 1983
                     V  L    F  GS      D    G+ S L    N+ +    C     + +
Sbjct: 851  -------SQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY----CGTDIPSFI 899

Query: 1984 ICSGNHLSTPAPFLNITRPN--------TDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCV 2035
                N L       + T  +         D +CG  L++ +G   SP +P  YP+   C 
Sbjct: 900  TSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCT 959

Query: 2036 WDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSS 2092
            W I VQ N+ + ++F    LE    C  DY+EV+D    +S  + R C      S TSS 
Sbjct: 960  WHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSG 1017

Query: 2093 NFMSIRFISDHSITRRGFRAEYYSSPSNDSTNLLCLPNHMQASVSRSYLQSLGFSASDLV 2152
            N + + F++D  +   GF   Y +     S    CL         + Y   LG   S   
Sbjct: 1018 NSLMLVFVTDSDLAYEGFLINYEAI----SAATACL---------QDYTDDLGTFTSPNF 1064

Query: 2153 ISTWNGYYECRPQIT 2167
             + +   +EC  +IT
Sbjct: 1065 PNNYPNNWECIYRIT 1079



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 99/377 (26%), Positives = 153/377 (40%), Gaps = 51/377 (13%)

Query: 1766 CGGFLFYASGT--FSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
            CGGFL          SP +P  Y N   C W I+      + L   +L +E+H  C++D 
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESHRTCAYDS 2036

Query: 1824 VEIFDGSLNSSLLLGKICNDTRQI---FTSSYNRMTIHFRSDISFQNTGFLAWYN----- 1875
            + I DG  N +  L  +C   R+I     S+   M I F SD S    GF A ++     
Sbjct: 2037 LVIRDGDNNLAQQLAVLCG--REIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGG 2094

Query: 1876 ---------SFPSDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQ 1926
                     + P        NLN     C+  V +  G T     +  + I   +  C Q
Sbjct: 2095 YLHADRGIITSPKYPETYPSNLN-----CSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQ 2149

Query: 1927 LGCGRAVSALGNAYFGSGSGPITLDDVEC-SGTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
                  V   G        GP   +   C S   STL+   N+ +     +H  +     
Sbjct: 2150 --GDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEG---- 2203

Query: 1986 SGNHLSTPAPFLNITRPNTDYSCGGFL----SQPSGDFSSPFYPGNYPNNAKCVWDIEVQ 2041
             G  +   A  L         +CGG +    +  +G  +SP +P NYP +A C+W +   
Sbjct: 2204 QGFKIKYEAKSL---------ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAP 2254

Query: 2042 NNYRVTVIFR---DVQLEGGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSI 2097
               R+ + F    D+++   C  +Y+E+ DG    +P++++ C      S  SS   M +
Sbjct: 2255 PETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYL 2314

Query: 2098 RFISDHSITRRGFRAEY 2114
            RF SD+S T  GF+A+Y
Sbjct: 2315 RFRSDNSPTHVGFKAKY 2331



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 97/386 (25%), Positives = 148/386 (38%), Gaps = 59/386 (15%)

Query: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVE 1825
            CG  L    G   SP +P  YP    C W I       I L F+  ++ +  +C  DYVE
Sbjct: 817  CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875

Query: 1826 IFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFPSDATLR 1884
            I   S+  S    K C  D     TS YN + + F    S +N GF+A +          
Sbjct: 876  IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF---------- 925

Query: 1885 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEA---EVVCRQLGCGRAVSALGNAYF 1941
                 S+  L  G +          + + + TIQ      V    + C   +    N   
Sbjct: 926  -----SAEDLACGEI----------LTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLI 970

Query: 1942 GSGSGPITLD-DVECSGTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPAPFLNIT 2000
                    L+    C+     ++   +       C       +  SGN L      + + 
Sbjct: 971  HLMFETFHLEFHYNCTNDYLEVYDTDSETSLGRYCGKSIPPSLTSSGNSL------MLVF 1024

Query: 2001 RPNTDYSCGGFL----------------SQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNY 2044
              ++D +  GFL                +   G F+SP +P NYPNN +C++ I V+   
Sbjct: 1025 VTDSDLAYEGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQ 1084

Query: 2045 RVTVIFRDVQLE---GGCNYDYIEVFDGPYRSSPLIARVCDGAR--GSFTSSSNFMSIRF 2099
             + V F +  LE   G    D++E+ DG Y  SPL+  +  G+    +  S SN + ++F
Sbjct: 1085 LIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLG-IFYGSNLPPTIISHSNKLWLKF 1143

Query: 2100 ISDHSITRRGFRAEYYSSPSNDSTNL 2125
             SD   TR GF A +  S +    NL
Sbjct: 1144 KSDQIDTRSGFSAYWDGSSTGCGGNL 1169



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 87/372 (23%), Positives = 154/372 (41%), Gaps = 29/372 (7%)

Query: 1762 PSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF 1821
            P   CG  L   +G+FS  S    Y ++  C W I+   G  + + F+  +LE+  NC  
Sbjct: 470  PQQVCGESLSGINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529

Query: 1822 DYVEIFDGSLNSSLLLGKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGF-LAWYNSFPS 1879
            ++++++DG  +S+  LG+ C  +      SS N +  H  S+      GF + W    P 
Sbjct: 530  EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 589

Query: 1880 DATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAV----SA 1935
               +    L   YG         + G +    D  W +  +  +      G         
Sbjct: 590  CGGI----LTGPYGSIKSP---GYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDD 642

Query: 1936 LGNAYFGSGSGPITLDDVECS-GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHLSTPA 1994
                Y     GP+  D +     T  ++   +  G F+   +   D+ +   G H++   
Sbjct: 643  CNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFA-RIHFHSDSQISDQGFHIT--- 698

Query: 1995 PFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQ 2054
                +T P +D  CGG  + P G+   P   G + +  +CV+ ++     ++ + F  V+
Sbjct: 699  ---YLTSP-SDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVE 754

Query: 2055 L--EGGCNYDYIEVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFR 2111
            L  +   + +YIEV DG      L+ +VC +G      S +N + IRF  D S+ +  FR
Sbjct: 755  LQCQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFR 810

Query: 2112 AEYYSSPSNDST 2123
            A Y  +  ++ T
Sbjct: 811  AVYQVACGDELT 822



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 41/113 (36%), Positives = 59/113 (52%), Gaps = 4/113 (3%)

Query: 2008 CGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIE 2065
            CGG L    G F+SP YPG YPNN  C W +       VT+ F  + ++  G C  +Y+ 
Sbjct: 3511 CGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570

Query: 2066 VFDGPYRSSPLIARVCDG--ARGSFTSSSNFMSIRFISDHSITRRGFRAEYYS 2116
            ++DGP  SSP     C G  +   F +SSN + I+F +D++     FR  + S
Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLTWDS 3623



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 45/115 (39%), Positives = 63/115 (54%), Gaps = 5/115 (4%)

Query: 1765 NCGGFLFYASGTFSSPSYP-AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDY 1823
            +CGG   ++SG  +SP+Y  A YPN+  C++ I V+    I L FS+  +    +CS DY
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095

Query: 1824 VEIFDGSLNSSLLLGKICNDTR-QIFTSSYNRMTIHFRSDISFQNTGFLAWYNSF 1877
            + I+DG+  S  LLGK C   R     SS N M + F++D SFQ      W  SF
Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTA--KGWKMSF 3147



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 41/132 (31%), Positives = 68/132 (51%), Gaps = 5/132 (3%)

Query: 1745 NSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRI 1804
            +S T+D  +    T++   S CGG L+   G+F+SP YP  YPNN  C W +   +G  +
Sbjct: 3492 DSVTSDRGYEIIWTSS--PSGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLV 3549

Query: 1805 NLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICNDTRQI--FTSSYNRMTIHFRSD 1862
             + F  + ++   +C  +Y+ ++DG   SS   G  C     I  F +S N++ I F +D
Sbjct: 3550 TINFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHAD 3609

Query: 1863 ISFQNTGF-LAW 1873
             + + + F L W
Sbjct: 3610 YARRPSAFRLTW 3621



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 35/112 (31%), Positives = 61/112 (54%), Gaps = 4/112 (3%)

Query: 2007 SCGGFLSQPSGDFSSPFYP-GNYPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCNYDY 2063
            SCGG  +  SG  +SP Y   +YPN+  C++ I V ++  + + F D  +     C++DY
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDY 3095

Query: 2064 IEVFDGPYRSSPLIARVCDGAR-GSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
            + ++DG   S PL+ + C   R  +  SS+N M + F +D   T +G++  +
Sbjct: 3096 LAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSF 3147



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 50/206 (24%), Positives = 85/206 (41%), Gaps = 11/206 (5%)

Query: 1683 CGWAMSAPGNARFGQGSGPIVLDDVRCSGNESYLWSCP--HKGWLTHNCGHHEDAGVICS 1740
            C W + +P + +       + L    C+ N   L   P  H       CG +  A V   
Sbjct: 3306 CTWVIDSPPHQQVKITVWALQLTSQDCTQNYLQLQDSPQGHGNSRFQFCGRNASA-VPVF 3364

Query: 1741 ATQINSTTTDWWHPTTTTTARPS-----SNCGGFLFYASGTFSSPSYPAYYPNNAKCVWE 1795
             + +++    +        +R S     ++C      A G   SP +P  Y N+  C   
Sbjct: 3365 YSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYHKAFGNLRSPGWPDNYDNDKDCTVT 3424

Query: 1796 IEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICND--TRQIFTSSYN 1853
            +     + I+L F +L +E    C  D++E+ +GS ++S LLGK C       +F S  N
Sbjct: 3425 LTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVF-SQNN 3483

Query: 1854 RMTIHFRSDISFQNTGFLAWYNSFPS 1879
             + + F+SD    + G+   + S PS
Sbjct: 3484 ELYLRFKSDSVTSDRGYEIIWTSSPS 3509



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 12/123 (9%)

Query: 1765 NCGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSF--- 1821
            +CGG+L    G  +SP YP  YP+N  C W + V SG  I + F       + + S    
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150

Query: 1822 DYVEIFDGSLNSSLLL------GKICND--TRQIFTSSYNRMTIHFRSDISFQNTGFLAW 1873
            DY+ + +G    S  L      G  C    +  +FTS  N+M + F SD S +  GF   
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSD-NQMFVQFISDHSNEGQGFKIK 2209

Query: 1874 YNS 1876
            Y +
Sbjct: 2210 YEA 2212



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 8/108 (7%)

Query: 2012 LSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYIEVFDG 2069
            ++Q  G   S  YP  Y  N  C W I       V   F    LE    C+ DY+E++DG
Sbjct: 1284 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1343

Query: 2070 PYRSSPLIARVC--DGARGSFTSSSNFMSIRFISDHSITRRGFRAEYY 2115
            P +    + R C  D      T+SS    +          +GF+ +++
Sbjct: 1344 PRQ----MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWF 1387


>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
          Length = 782

 Score =  121 bits (304), Expect = 7e-27
 Identities = 63/113 (55%), Positives = 73/113 (64%), Gaps = 1/113 (0%)

Query: 352 ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 411
           AS A  +  + L    G     GRVEV   G WGTVCDDSW+ S A VVCRQLG  +A  
Sbjct: 664 ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723

Query: 412 APGNARFGQ-GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
           A   A FGQ GS PI+LDDVRC+G+E  L  C HNG  +HNC+H EDAGV+CS
Sbjct: 724 AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  121 bits (304), Expect = 7e-27
 Identities = 63/113 (55%), Positives = 73/113 (64%), Gaps = 1/113 (0%)

Query: 851 ASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATS 910
           AS A  +  + L    G     GRVEV   G WGTVCDDSW+ S A VVCRQLG  +A  
Sbjct: 664 ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723

Query: 911 APGNARFGQ-GSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962
           A   A FGQ GS PI+LDDVRC+G+E  L  C HNG  +HNC+H EDAGV+CS
Sbjct: 724 AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  117 bits (293), Expect = 1e-25
 Identities = 57/91 (62%), Positives = 65/91 (71%), Gaps = 1/91 (1%)

Query: 245 GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ-GSGPIVLDDVRC 303
           GRVEV   G WGTVCDD W+ + A VVCRQLG  +A+ A   A+FGQ GS PI+LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 304 SGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           +G E  L  C HNG  THNC H EDAGV+CS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  117 bits (293), Expect = 1e-25
 Identities = 57/91 (62%), Positives = 65/91 (71%), Gaps = 1/91 (1%)

Query: 1004 GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ-GSGPIVLDDVRC 1062
            GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A+ A   A FGQ GS PI+LDDVRC
Sbjct: 686  GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 1063 SGHESYLWSCPHNGWLSHNCGHSEDAGVICS 1093
            +G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 746  AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  117 bits (292), Expect = 2e-25
 Identities = 61/104 (58%), Positives = 69/104 (66%), Gaps = 3/104 (2%)

Query: 733 LRLVN--GSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQ 790
           +RLV   G     GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A  A   A FGQ
Sbjct: 673 VRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQ 732

Query: 791 -GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 833
            GS PI+LDDVRC+G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 733 GGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  116 bits (290), Expect = 3e-25
 Identities = 57/95 (60%), Positives = 65/95 (68%), Gaps = 1/95 (1%)

Query: 113 GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQ-GSGPIALDDVRC 171
           GRVE+   G WGTVCDDSW+ + A VVCRQLG  +A+ A   A FGQ GS PI LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 172 SGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQP 206
           +G E  L  C HNG  +HNC H EDAGV+CS   P
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQNP 780



 Score =  116 bits (290), Expect = 3e-25
 Identities = 57/91 (62%), Positives = 65/91 (71%), Gaps = 1/91 (1%)

Query: 505 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQ-GSGPIVLDDVRC 563
           GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A+ A   A FGQ GS PI+LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 564 SGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
           +G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (289), Expect = 4e-25
 Identities = 69/146 (47%), Positives = 82/146 (56%), Gaps = 16/146 (10%)

Query: 1480 SASQSQPTPSP---DTWPTSR------------ASTAGSESTLALRLVNGGDRCRGRVEV 1524
            +A+   PTP P      P SR            AS A  +  + L    G     GRVEV
Sbjct: 631  TAAPPAPTPRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSGRVEV 690

Query: 1525 LYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ-GSGPIVLDDVRCSGHES 1583
               G WGTVCDD W+ + A VVCRQLG  +A+ A   A+FGQ GS PI+LDDVRC+G E 
Sbjct: 691  FVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCAGWER 750

Query: 1584 YLWSCPHNGWLSHNCGHHEDAGVICS 1609
             L  C HNG  +HNC H EDAGV+CS
Sbjct: 751  NLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (288), Expect = 5e-25
 Identities = 61/113 (53%), Positives = 71/113 (62%), Gaps = 1/113 (0%)

Query: 1111 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMS 1170
            AS A  +  + L    G     GRVEV   G WGTVCDD W+ + A VVCRQLG  +A+ 
Sbjct: 664  ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723

Query: 1171 APGNARFGQ-GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1222
            A   A FGQ GS PI+LDDVRC+G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 724  AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (288), Expect = 5e-25
 Identities = 57/91 (62%), Positives = 64/91 (70%), Gaps = 1/91 (1%)

Query: 1651 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQ-GSGPIVLDDVRC 1709
            GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A+ A   A FGQ GS PI+LDDVRC
Sbjct: 686  GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 1710 SGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            +G E  L  C H G  THNC H EDAGV+CS
Sbjct: 746  AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (287), Expect = 7e-25
 Identities = 61/113 (53%), Positives = 70/113 (61%), Gaps = 1/113 (0%)

Query: 1240 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 1299
            AS A  +  + L    G     GRVEV   G WGTVCDD W+ + A VVCRQLG  +A  
Sbjct: 664  ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723

Query: 1300 APGNARFGQ-GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1351
            A   A FGQ GS PI+LDDVRC+G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 724  AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (287), Expect = 7e-25
 Identities = 61/113 (53%), Positives = 70/113 (61%), Gaps = 1/113 (0%)

Query: 1369 ASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATS 1428
            AS A  +  + L    G     GRVEV   G WGTVCDD W+ + A VVCRQLG  +A  
Sbjct: 664  ASRAFRDGEVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVR 723

Query: 1429 APGNARFGQ-GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
            A   A FGQ GS PI+LDDVRC+G E  L  C HNG  +HNC H EDAGV+CS
Sbjct: 724  AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  115 bits (287), Expect = 7e-25
 Identities = 55/92 (59%), Positives = 65/92 (70%), Gaps = 1/92 (1%)

Query: 1896 AGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-SGSGPITLDDVE 1954
            +GRVE++ GG WGTVCDDSW I  A VVCRQLG   AV A+  A FG  GS PI LDDV 
Sbjct: 685  SGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVR 744

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            C+G E  L +C++ G  +HNC H EDAGV+CS
Sbjct: 745  CAGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776



 Score =  114 bits (284), Expect = 2e-24
 Identities = 56/91 (61%), Positives = 64/91 (70%), Gaps = 1/91 (1%)

Query: 613 GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQ-GSGPIVLDDVRC 671
           GRVEV   G WGTVCDDSW+ + A VVCRQLG  +A  A   A FGQ GS PI+LDDVRC
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745

Query: 672 SGHESYLWSCPNNGWLSHNCGHHEDAGVICS 702
           +G E  L  C +NG  +HNC H EDAGV+CS
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCS 776


>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
          Length = 495

 Score =  114 bits (285), Expect = 1e-24
 Identities = 56/119 (47%), Positives = 68/119 (57%)

Query: 584 GHSEDAGVICSGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 643
           G   D     SG E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR L
Sbjct: 375 GEKGDRAGDASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRML 434

Query: 644 GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 702
           G          ARFGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 435 GFRGVEEVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  114 bits (284), Expect = 2e-24
 Identities = 54/108 (50%), Positives = 66/108 (61%)

Query: 726 GSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGN 785
           G E+ + +RLVNGS   +GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 786 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 833
           ARFGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  114 bits (284), Expect = 2e-24
 Identities = 53/108 (49%), Positives = 66/108 (61%)

Query: 986  GSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 1045
            G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386  GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 1046 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 1093
            ARFGQG+G I +DDV C G E  ++ C  + W   NCGH+EDA V C+
Sbjct: 446  ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  112 bits (281), Expect = 3e-24
 Identities = 53/108 (49%), Positives = 66/108 (61%)

Query: 487 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 546
           G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 547 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
           ARFGQG+G I +DDV C G E  ++ C  + W   NCGH+EDA V C+
Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  112 bits (280), Expect = 4e-24
 Identities = 53/108 (49%), Positives = 63/108 (58%)

Query: 1633 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 1692
            G E+ + +RLVNG     GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386  GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 1693 ARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            ARFGQG+G I +DDV C G E  ++ C    W   NCGH EDA V C+
Sbjct: 446  ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  112 bits (279), Expect = 6e-24
 Identities = 52/110 (47%), Positives = 66/110 (60%)

Query: 93  AEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAP 152
           A G ++ + +RLVNG G  +GRVE+ +   WGTVCDD WD  D +VVCR LG        
Sbjct: 384 ASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVY 443

Query: 153 GNAWFGQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
             A FGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 444 RTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  111 bits (278), Expect = 8e-24
 Identities = 53/109 (48%), Positives = 66/109 (60%)

Query: 1243 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1302
            +G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385  SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 1303 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1351
             ARFGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 445  TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  111 bits (278), Expect = 8e-24
 Identities = 53/109 (48%), Positives = 66/109 (60%)

Query: 1372 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPG 1431
            +G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385  SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 1432 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
             ARFGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 445  TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  111 bits (277), Expect = 1e-23
 Identities = 53/109 (48%), Positives = 66/109 (60%)

Query: 1114 AGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 1173
            +G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385  SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 1174 NARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1222
             ARFGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 445  TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  110 bits (276), Expect = 1e-23
 Identities = 52/109 (47%), Positives = 66/109 (60%)

Query: 355 AGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 414
           +G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 415 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
            ARFGQG+G I +DDV C G E  ++ C  + W   NC H+EDA V C+
Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  110 bits (276), Expect = 1e-23
 Identities = 52/109 (47%), Positives = 66/109 (60%)

Query: 854 AGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPG 913
           +G E+ + +RLVNG    +GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385 SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 914 NARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962
            ARFGQG+G I +DDV C G E  ++ C  + W   NC H+EDA V C+
Sbjct: 445 TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  110 bits (275), Expect = 2e-23
 Identities = 52/108 (48%), Positives = 65/108 (60%)

Query: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
           G E+ + +RLVNG     GRVEV +   WGTVCDD WD  D +VVCR LG          
Sbjct: 386 GVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRT 445

Query: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           A+FGQG+G I +DDV C G E  ++ C  + W   NCGH+EDA V C+
Sbjct: 446 ARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  109 bits (273), Expect = 3e-23
 Identities = 52/109 (47%), Positives = 65/109 (59%)

Query: 1501 AGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 1560
            +G E+ + +RLVNG     GRVEV +   WGTVCDD WD  D +VVCR LG         
Sbjct: 385  SGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYR 444

Query: 1561 NAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609
             A+FGQG+G I +DDV C G E  ++ C  + W   NCGH EDA V C+
Sbjct: 445  TARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493



 Score =  101 bits (252), Expect = 8e-21
 Identities = 46/102 (45%), Positives = 59/102 (57%)

Query: 1885 LVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG 1944
            ++ L +  G   GRVE+YH   WGTVCDD W  ++ +VVCR LG          A FG G
Sbjct: 392  MIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQG 451

Query: 1945 SGPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            +G I +DDV C GTE T+++C    W   NC H EDA V C+
Sbjct: 452  TGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493


>gi|5803080 macrophage receptor with collagenous structure [Homo
           sapiens]
          Length = 520

 Score =  112 bits (281), Expect = 3e-24
 Identities = 56/109 (51%), Positives = 71/109 (65%), Gaps = 9/109 (8%)

Query: 728 ESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNAR 787
           E+S+++R+V  S+R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 788 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 834
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CSV
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV 520



 Score =  110 bits (276), Expect = 1e-23
 Identities = 55/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 358 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNAR 417
           E+S+++R+V   +R  GR EV Y G+WGT+CDD W  SDA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 418 F--GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (276), Expect = 1e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 489 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNAR 548
           E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLG-----YSKGRAL 471

Query: 549 F--GQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (276), Expect = 1e-23
 Identities = 55/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 857 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNAR 916
           E+S+++R+V   +R  GR EV Y G+WGT+CDD W  SDA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 917 F--GQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (274), Expect = 2e-23
 Identities = 56/111 (50%), Positives = 70/111 (63%), Gaps = 9/111 (8%)

Query: 226 EGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPG 285
           E  E+S+++R+V  G   RGR EV Y G+WGT+CDD W  +DA V CR LG      + G
Sbjct: 416 ERGENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKG 468

Query: 286 NAQF--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
            A +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 469 RALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (274), Expect = 2e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 597 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNAR 656
           E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419 ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 657 F--GQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 702
           +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472 YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  110 bits (274), Expect = 2e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 988  ESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 1047
            E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419  ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 1048 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 1093
            +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472  YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (271), Expect = 5e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 1117 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAR 1176
            E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419  ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 1177 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1222
            +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472  YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (271), Expect = 5e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 1246 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNAR 1305
            E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419  ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 1306 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1351
            +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472  YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (271), Expect = 5e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 1375 ESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNAR 1434
            E+S+++R+V   +R  GR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419  ENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 1435 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
            +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472  YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (270), Expect = 6e-23
 Identities = 54/108 (50%), Positives = 69/108 (63%), Gaps = 9/108 (8%)

Query: 1504 ESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQ 1563
            E+++++R+V  G   RGR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419  ENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 1564 F--GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609
            +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 472  YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  108 bits (269), Expect = 8e-23
 Identities = 54/108 (50%), Positives = 68/108 (62%), Gaps = 9/108 (8%)

Query: 1635 ESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAR 1694
            E+S+++R+V  G   RGR EV Y G+WGT+CDD W  +DA V CR LG      + G A 
Sbjct: 419  ENSVSVRIV--GSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGY-----SKGRAL 471

Query: 1695 F--GQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            +  G G+G I LD+V+C G ES LWSC    W  H+C H EDAGV CS
Sbjct: 472  YKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  107 bits (268), Expect = 1e-22
 Identities = 48/92 (52%), Positives = 60/92 (65%), Gaps = 7/92 (7%)

Query: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYF--GSGSGPITLDDVE 1954
            GR E+Y+ GTWGT+CDD W   +A V CR LG  +     G A +  G+G+G I LD+V+
Sbjct: 433  GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSK-----GRALYKVGAGTGQIWLDNVQ 487

Query: 1955 CSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            C GTESTLW C    W  H+C+H EDAGV CS
Sbjct: 488  CRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519



 Score =  107 bits (267), Expect = 1e-22
 Identities = 53/120 (44%), Positives = 71/120 (59%), Gaps = 9/120 (7%)

Query: 85  ESTLESTVAEGSDSGLALRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLG 144
           E  ++    E  ++ +++R+V    R  GR E+ Y G+WGT+CDD W  +DA V CR LG
Sbjct: 407 EQGVKGEKGERGENSVSVRIVGSSNR--GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLG 464

Query: 145 CGWAMSAPGNAWF--GQGSGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
                 + G A +  G G+G I LD+V+C G ES LWSC  N W  H+C H EDAGV CS
Sbjct: 465 Y-----SKGRALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519


>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
           sapiens]
          Length = 451

 Score =  105 bits (262), Expect = 5e-22
 Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 4/113 (3%)

Query: 726 GSESSLT----LRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 781
           GS ++LT    +RLV GS   +GRVE+L+ G WGT+CDD W+     VVCR LG     +
Sbjct: 339 GSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQA 398

Query: 782 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 834
               A FGQG+GPI L++V C G ES +  C    W +  C H EDAGV C++
Sbjct: 399 VHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL 451



 Score =  105 bits (261), Expect = 7e-22
 Identities = 49/101 (48%), Positives = 61/101 (60%)

Query: 102 LRLVNGDGRCQGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGS 161
           +RLV G G  +GRVEIL+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 162 GPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICS 202
           GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  104 bits (260), Expect = 9e-22
 Identities = 49/101 (48%), Positives = 60/101 (59%)

Query: 234 LRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGS 293
           +RLV G     GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 294 GPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICS 334
           GPI L++V C G ES +  C    W T  C HSEDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  104 bits (260), Expect = 9e-22
 Identities = 48/101 (47%), Positives = 61/101 (60%)

Query: 993  LRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1052
            +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350  VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 1053 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICS 1093
            GPI L++V C G ES +  C    W +  C HSEDAGV C+
Sbjct: 410  GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  104 bits (259), Expect = 1e-21
 Identities = 52/120 (43%), Positives = 66/120 (55%), Gaps = 4/120 (3%)

Query: 1494 PTSRASTAGSESTLA----LRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQ 1549
            P  +    GS +TL     +RLV G     GRVE+L+ G WGT+CDD W+     VVCR 
Sbjct: 331  PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390

Query: 1550 LGCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1609
            LG     +    A FGQG+GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 391  LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  103 bits (258), Expect = 2e-21
 Identities = 48/101 (47%), Positives = 60/101 (59%)

Query: 1640 LRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGS 1699
            +RLV G     GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350  VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 1700 GPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
            GPI L++V C G ES +  C  + W T  C H EDAGV C+
Sbjct: 410  GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  103 bits (257), Expect = 2e-21
 Identities = 48/101 (47%), Positives = 60/101 (59%)

Query: 494 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 553
           +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR LG          A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 554 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICS 594
           GPI L++V C G ES +  C    W +  C HSEDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (255), Expect = 3e-21
 Identities = 51/120 (42%), Positives = 66/120 (55%), Gaps = 4/120 (3%)

Query: 1107 PTSHASTAGSESSLA----LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1162
            P       GS ++L     +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR 
Sbjct: 331  PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390

Query: 1163 LGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1222
            LG     +    A FGQG+GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 391  LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (255), Expect = 3e-21
 Identities = 48/101 (47%), Positives = 61/101 (60%)

Query: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
           +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 463
           GPI L++V C G ES +  C    W +  C HSEDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (255), Expect = 3e-21
 Identities = 48/101 (47%), Positives = 61/101 (60%)

Query: 862 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 921
           +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 922 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICS 962
           GPI L++V C G ES +  C    W +  C HSEDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (255), Expect = 3e-21
 Identities = 47/101 (46%), Positives = 63/101 (62%)

Query: 1886 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1945
            V L    G   GRVEI H G WGT+CDD W ++  +VVCR LG     +    A+FG G+
Sbjct: 350  VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 1946 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
            GPI L++V C G ES++ +C+ R W +  C+H EDAGV C+
Sbjct: 410  GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (254), Expect = 5e-21
 Identities = 51/120 (42%), Positives = 66/120 (55%), Gaps = 4/120 (3%)

Query: 1236 PTSHASTAGSESSLA----LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1291
            P       GS ++L     +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR 
Sbjct: 331  PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390

Query: 1292 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1351
            LG     +    A FGQG+GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 391  LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (254), Expect = 5e-21
 Identities = 51/120 (42%), Positives = 66/120 (55%), Gaps = 4/120 (3%)

Query: 1365 PTSHASTAGSESSLA----LRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQ 1420
            P       GS ++L     +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR 
Sbjct: 331  PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390

Query: 1421 LGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICS 1480
            LG     +    A FGQG+GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 391  LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450



 Score =  102 bits (253), Expect = 6e-21
 Identities = 47/101 (46%), Positives = 60/101 (59%)

Query: 602 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGS 661
           +RLV G    +GRVE+L+ G WGT+CDD W+     VVCR LG     +    A FGQG+
Sbjct: 350 VRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGT 409

Query: 662 GPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 702
           GPI L++V C G ES +  C    W +  C H EDAGV C+
Sbjct: 410 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,136,208
Number of Sequences: 37866
Number of extensions: 5850180
Number of successful extensions: 18839
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 101
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 15341
Number of HSP's gapped (non-prelim): 1502
length of query: 2413
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2294
effective length of database: 13,741,464
effective search space: 31522918416
effective search space used: 31522918416
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.