Search of human proteins with 14589946

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
         (1340 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]       2670   0.0  
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]       2532   0.0  
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]       2528   0.0  
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]       2066   0.0  
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]       2029   0.0  
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ...  1964   0.0  
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s...  1961   0.0  
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]        1296   0.0  
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]       1281   0.0  
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]        692   0.0  
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]        654   0.0  
gi|190194360 protocadherin 20 [Homo sapiens]                          623   e-178
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]        615   e-175
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]        607   e-173
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]        607   e-173
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   365   e-100
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur...   365   e-100
gi|14589929 protocadherin 18 precursor [Homo sapiens]                 360   5e-99
gi|157426847 protocadherin 19 isoform a [Homo sapiens]                355   2e-97
gi|157426845 protocadherin 19 isoform b [Homo sapiens]                355   2e-97
gi|94538350 protocadherin 17 precursor [Homo sapiens]                 355   2e-97
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   352   1e-96
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur...   352   1e-96
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs...   349   1e-95
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs...   349   1e-95
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]       348   3e-95
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]       348   3e-95
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs...   346   8e-95
gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precurs...   346   8e-95
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur...   345   2e-94

>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
          Length = 1340

 Score = 2670 bits (6920), Expect = 0.0
 Identities = 1340/1340 (100%), Positives = 1340/1340 (100%)

Query: 1    MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 60
            MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY
Sbjct: 1    MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 60

Query: 61   TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 120
            TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG
Sbjct: 61   TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 120

Query: 121  ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 180
            ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI
Sbjct: 121  ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 180

Query: 181  PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 240
            PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD
Sbjct: 181  PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 240

Query: 241  REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300
            REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV
Sbjct: 241  REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300

Query: 301  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360
            TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL
Sbjct: 301  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360

Query: 361  ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 420
            ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK
Sbjct: 361  ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 420

Query: 421  DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 480
            DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ
Sbjct: 421  DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 480

Query: 481  SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 540
            SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD
Sbjct: 481  SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 540

Query: 541  APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 600
            APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP
Sbjct: 541  APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 600

Query: 601  VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 660
            VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN
Sbjct: 601  VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 660

Query: 661  ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 720
            ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS
Sbjct: 661  ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 720

Query: 721  TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 780
            TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR
Sbjct: 721  TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 780

Query: 781  VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 840
            VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS
Sbjct: 781  VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 840

Query: 841  DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 900
            DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK
Sbjct: 841  DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 900

Query: 901  KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 960
            KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF
Sbjct: 901  KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 960

Query: 961  KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 1020
            KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP
Sbjct: 961  KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 1020

Query: 1021 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL 1080
            YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL
Sbjct: 1021 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL 1080

Query: 1081 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG 1140
            PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG
Sbjct: 1081 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG 1140

Query: 1141 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL 1200
            HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL
Sbjct: 1141 HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL 1200

Query: 1201 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL 1260
            CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL
Sbjct: 1201 CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL 1260

Query: 1261 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA 1320
            HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA
Sbjct: 1261 HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA 1320

Query: 1321 PRQQARPSRGDSPIMETHPL 1340
            PRQQARPSRGDSPIMETHPL
Sbjct: 1321 PRQQARPSRGDSPIMETHPL 1340


>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
          Length = 1337

 Score = 2532 bits (6563), Expect = 0.0
 Identities = 1282/1335 (96%), Positives = 1286/1335 (96%), Gaps = 29/1335 (2%)

Query: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
            LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62

Query: 95   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154
            FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122

Query: 155  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214
            VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182

Query: 215  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274
            NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242

Query: 275  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334
            NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302

Query: 335  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394
            NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362

Query: 395  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454
            PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422

Query: 455  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514
            YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482

Query: 515  IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574
            IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483  IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542

Query: 575  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634
            KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602

Query: 635  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
            SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662

Query: 695  VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
            VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663  VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722

Query: 755  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
            LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782

Query: 815  NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874
            NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783  NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842

Query: 875  KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934
            KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843  KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902

Query: 935  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994
            VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962

Query: 995  IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP----------- 1043
            IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP           
Sbjct: 963  IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTP 1022

Query: 1044 ----------------SQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQE 1087
                            SQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQE
Sbjct: 1023 MKESTTMEIWIHPQPQSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQE 1082

Query: 1088 EYFDRATPSNRTEGDGNSDPESTFIPGLKK--EITVQPTVEEASDNCTQECLIYGHSDAC 1145
            EYFDRATPSNRTEGDGNSDPESTFIPGLKK  EITVQPTVEEASDNCTQECLIYGHSDAC
Sbjct: 1083 EYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYGHSDAC 1142

Query: 1146 WMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIALCHSPP 1205
            WMPASLDHSSSSQAQASALCHSPPLSQASTQHHSP VTQTI LCHSPPVTQTIALCHSPP
Sbjct: 1143 WMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVTQTIALCHSPP 1202

Query: 1206 PIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIALHRSQA 1265
            PIQVSALHHSPPLVQ TALHHSPPSAQASALCYSPPLAQAAAISHSS LPQVIALHRSQA
Sbjct: 1203 PIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLPQVIALHRSQA 1262

Query: 1266 QSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFAPRQQA 1325
            QSSVSLQQGWVQGA+GLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTF PRQQA
Sbjct: 1263 QSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFTPRQQA 1322

Query: 1326 RPSRGDSPIMETHPL 1340
            RPSRGDSPIME HPL
Sbjct: 1323 RPSRGDSPIMEEHPL 1337


>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
          Length = 1347

 Score = 2528 bits (6553), Expect = 0.0
 Identities = 1282/1345 (95%), Positives = 1286/1345 (95%), Gaps = 39/1345 (2%)

Query: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
            LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62

Query: 95   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154
            FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122

Query: 155  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214
            VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182

Query: 215  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274
            NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242

Query: 275  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334
            NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302

Query: 335  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394
            NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362

Query: 395  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454
            PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422

Query: 455  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514
            YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482

Query: 515  IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574
            IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483  IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542

Query: 575  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634
            KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602

Query: 635  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
            SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662

Query: 695  VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
            VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663  VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722

Query: 755  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
            LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782

Query: 815  NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874
            NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783  NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842

Query: 875  KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934
            KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843  KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902

Query: 935  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994
            VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962

Query: 995  IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP----------- 1043
            IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP           
Sbjct: 963  IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVRSCTP 1022

Query: 1044 --------------------------SQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTS 1077
                                      SQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTS
Sbjct: 1023 MKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTS 1082

Query: 1078 HGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK--EITVQPTVEEASDNCTQE 1135
            HGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKK  EITVQPTVEEASDNCTQE
Sbjct: 1083 HGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQE 1142

Query: 1136 CLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVT 1195
            CLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSP VTQTI LCHSPPVT
Sbjct: 1143 CLIYGHSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPRVTQTIALCHSPPVT 1202

Query: 1196 QTIALCHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLP 1255
            QTIALCHSPPPIQVSALHHSPPLVQ TALHHSPPSAQASALCYSPPLAQAAAISHSS LP
Sbjct: 1203 QTIALCHSPPPIQVSALHHSPPLVQATALHHSPPSAQASALCYSPPLAQAAAISHSSPLP 1262

Query: 1256 QVIALHRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIP 1315
            QVIALHRSQAQSSVSLQQGWVQGA+GLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIP
Sbjct: 1263 QVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIP 1322

Query: 1316 LTTFAPRQQARPSRGDSPIMETHPL 1340
            LTTF PRQQARPSRGDSPIME HPL
Sbjct: 1323 LTTFTPRQQARPSRGDSPIMEEHPL 1347


>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
          Length = 1048

 Score = 2066 bits (5353), Expect = 0.0
 Identities = 1044/1047 (99%), Positives = 1045/1047 (99%)

Query: 1    MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 60
            MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY
Sbjct: 1    MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY 60

Query: 61   TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 120
            TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG
Sbjct: 61   TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG 120

Query: 121  ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 180
            ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI
Sbjct: 121  ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI 180

Query: 181  PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 240
            PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD
Sbjct: 181  PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD 240

Query: 241  REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300
            REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV
Sbjct: 241  REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300

Query: 301  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360
            TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL
Sbjct: 301  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360

Query: 361  ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 420
            ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK
Sbjct: 361  ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK 420

Query: 421  DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 480
            DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ
Sbjct: 421  DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ 480

Query: 481  SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 540
            SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD
Sbjct: 481  SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD 540

Query: 541  APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 600
            APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP
Sbjct: 541  APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 600

Query: 601  VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 660
            VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN
Sbjct: 601  VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN 660

Query: 661  ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 720
            ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS
Sbjct: 661  ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS 720

Query: 721  TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 780
            TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR
Sbjct: 721  TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR 780

Query: 781  VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 840
            VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS
Sbjct: 781  VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS 840

Query: 841  DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 900
            DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK
Sbjct: 841  DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK 900

Query: 901  KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 960
            KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF
Sbjct: 901  KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF 960

Query: 961  KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 1020
            KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP
Sbjct: 961  KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP 1020

Query: 1021 YSVSDCGYPVTTFEVPVSVHTRPSQRR 1047
            YSVSDCGYPVTTFEVPVSVHTRP+  R
Sbjct: 1021 YSVSDCGYPVTTFEVPVSVHTRPTDSR 1047


>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
          Length = 1037

 Score = 2029 bits (5258), Expect = 0.0
 Identities = 1023/1026 (99%), Positives = 1024/1026 (99%)

Query: 22   SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL 81
            SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL
Sbjct: 11   SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL 70

Query: 82   SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE 141
            SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE
Sbjct: 71   SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE 130

Query: 142  VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG 201
            VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG
Sbjct: 131  VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG 190

Query: 202  INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR 261
            INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR
Sbjct: 191  INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR 250

Query: 262  SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 321
            SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS
Sbjct: 251  SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 310

Query: 322  NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN 381
            NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN
Sbjct: 311  NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN 370

Query: 382  DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
            DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR
Sbjct: 371  DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 430

Query: 442  PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 501
            PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS
Sbjct: 431  PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 490

Query: 502  FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 561
            FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD
Sbjct: 491  FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 550

Query: 562  REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV 621
            REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV
Sbjct: 551  REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV 610

Query: 622  GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
            GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG
Sbjct: 611  GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670

Query: 682  RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA 741
            RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA
Sbjct: 671  RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA 730

Query: 742  EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 801
            EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN
Sbjct: 731  EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 790

Query: 802  LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 861
            LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF
Sbjct: 791  LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 850

Query: 862  ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE 921
            ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE
Sbjct: 851  ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE 910

Query: 922  ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ 981
            ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ
Sbjct: 911  ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ 970

Query: 982  IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT 1041
            IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT
Sbjct: 971  IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT 1030

Query: 1042 RPSQRR 1047
            RP+  R
Sbjct: 1031 RPTDSR 1036


>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
            sapiens]
          Length = 1025

 Score = 1964 bits (5087), Expect = 0.0
 Identities = 993/1015 (97%), Positives = 998/1015 (98%)

Query: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
            LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62

Query: 95   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154
            FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122

Query: 155  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214
            VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182

Query: 215  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274
            NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242

Query: 275  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334
            NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302

Query: 335  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394
            NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362

Query: 395  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454
            PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422

Query: 455  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514
            YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482

Query: 515  IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574
            IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483  IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542

Query: 575  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634
            KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602

Query: 635  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
            SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662

Query: 695  VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
            VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663  VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722

Query: 755  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
            LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782

Query: 815  NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874
            NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783  NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842

Query: 875  KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934
            KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843  KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902

Query: 935  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994
            VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962

Query: 995  IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPSQRRVT 1049
            IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP+  R +
Sbjct: 963  IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTS 1017


>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
            sapiens]
          Length = 1021

 Score = 1961 bits (5081), Expect = 0.0
 Identities = 992/1009 (98%), Positives = 995/1009 (98%)

Query: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
            LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62

Query: 95   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154
            FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122

Query: 155  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214
            VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182

Query: 215  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274
            NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242

Query: 275  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334
            NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302

Query: 335  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394
            NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362

Query: 395  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454
            PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422

Query: 455  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514
            YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482

Query: 515  IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574
            IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483  IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542

Query: 575  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634
            KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602

Query: 635  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
            SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662

Query: 695  VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
            VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663  VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722

Query: 755  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
            LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782

Query: 815  NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874
            NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783  NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842

Query: 875  KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934
            KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843  KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902

Query: 935  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994
            VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962

Query: 995  IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1043
            IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 963  IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011


>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
          Length = 1203

 Score = 1296 bits (3354), Expect = 0.0
 Identities = 651/1122 (58%), Positives = 852/1122 (75%), Gaps = 24/1122 (2%)

Query: 40   YIFAVLLVCVVFHSG-AQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTT-TMQFKL 97
            Y+ A L+ C+   S  AQE  YTIREE+PENV IGN+ KDLN+S I   + T+ ++ ++L
Sbjct: 7    YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66

Query: 98   VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 155
            V K GD PL+++   TGEIFTT  RIDREKLCAG     +  CF+E+EV ILP++ FRL+
Sbjct: 67   VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126

Query: 156  KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 215
            KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+  Q+
Sbjct: 127  KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186

Query: 216  IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 275
            +FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187  VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246

Query: 276  DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 335
            DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F   V+   +RLF LN
Sbjct: 247  DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306

Query: 336  ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 395
             TTGLIT++  LDREET  HK+ VLASDG   PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307  NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366

Query: 396  VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 455
            +N TV LSE  P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLE ++ 
Sbjct: 367  INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426

Query: 456  LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 515
            LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q  + +S+ ENN  G+
Sbjct: 427  LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486

Query: 516  QLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAK 575
             L  +SATD DSG NA+I Y LGP+A   F LDR+TG+LT  +  DRE++++++FT+ A+
Sbjct: 487  YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545

Query: 576  DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS 635
            DNG PPL S   V V+++D+NDNSP FTHN ++F+V ENLP++ TVG+ITVTD D G+N 
Sbjct: 546  DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605

Query: 636  AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 695
            AVTLSIL++ND+F +D  +GVI+ N+SFDRE+Q SYTF VKA DGG+  RSS+AKVTINV
Sbjct: 606  AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665

Query: 696  VDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 755
            +DVNDN PV I PP N S++LV  S  PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666  MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725

Query: 756  FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 815
            F ID  TGNITL EK   TD+GLHR++V  +DLG P SL ++V+V L+VN++  NA+ I 
Sbjct: 726  FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785

Query: 816  ELVRKSIEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 873
            +L+R+++E P+  N  I D S P    DY+ I++A +AG + V+VVIF+T +VRCR A  
Sbjct: 786  DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843

Query: 874  LKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGN 933
             KAAQ++ Q +EW +PN EN+Q    KKKK+KK+ SPK+ LLN VTIEE+K DD   +  
Sbjct: 844  FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900

Query: 934  RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNL-K 991
              T+ LP +LEEQ++G+++W    PTTFKP+SPDLA+HYKSASPQPAF ++P+TP+++ K
Sbjct: 901  NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960

Query: 992  HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPSQRRVTF 1050
            HH+IQELPLDNTFV  CD++S  SS+SSD +S S+C      F+    +HTR SQRRVTF
Sbjct: 961  HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQSQRRVTF 1019

Query: 1051 HLPEGSQESSSDGGLGDHD-AGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPES 1109
            HLP+GSQES SD GLGDH+  GS T  SH LPL  PQ+E++D+A+P  RTE DGNSDP S
Sbjct: 1020 HLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS 1079

Query: 1110 TFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDACWMPASL 1151
                G +        + EA++ CTQECL+ GHSD CWMP  L
Sbjct: 1080 DGPLGPR-------GLAEATEMCTQECLVLGHSDNCWMPPGL 1114


>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
          Length = 1237

 Score = 1281 bits (3314), Expect = 0.0
 Identities = 653/1155 (56%), Positives = 854/1155 (73%), Gaps = 56/1155 (4%)

Query: 40   YIFAVLLVCVVFHSG-AQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTT-TMQFKL 97
            Y+ A L+ C+   S  AQE  YTIREE+PENV IGN+ KDLN+S I   + T+ ++ ++L
Sbjct: 7    YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66

Query: 98   VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 155
            V K GD PL+++   TGEIFTT  RIDREKLCAG     +  CF+E+EV ILP++ FRL+
Sbjct: 67   VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126

Query: 156  KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 215
            KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+  Q+
Sbjct: 127  KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186

Query: 216  IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 275
            +FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187  VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246

Query: 276  DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 335
            DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F   V+   +RLF LN
Sbjct: 247  DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306

Query: 336  ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 395
             TTGLIT++  LDREET  HK+ VLASDG   PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307  NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366

Query: 396  VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 455
            +N TV LSE  P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLE ++ 
Sbjct: 367  INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426

Query: 456  LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 515
            LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q  + +S+ ENN  G+
Sbjct: 427  LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486

Query: 516  QLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAK 575
             L  +SATD DSG NA+I Y LGP+A   F LDR+TG+LT  +  DRE++++++FT+ A+
Sbjct: 487  YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545

Query: 576  DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS 635
            DNG PPL S   V V+++D+NDNSP FTHN ++F+V ENLP++ TVG+ITVTD D G+N 
Sbjct: 546  DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605

Query: 636  AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 695
            AVTLSIL++ND+F +D  +GVI+ N+SFDRE+Q SYTF VKA DGG+  RSS+AKVTINV
Sbjct: 606  AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665

Query: 696  VDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 755
            +DVNDN PV I PP N S++LV  S  PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666  MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725

Query: 756  FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 815
            F ID  TGNITL EK   TD+GLHR++V  +DLG P SL ++V+V L+VN++  NA+ I 
Sbjct: 726  FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785

Query: 816  ELVRKSIEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 873
            +L+R+++E P+  N  I D S P    DY+ I++A +AG + V+VVIF+T +VRCR A  
Sbjct: 786  DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843

Query: 874  LKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGN 933
             KAAQ++ Q +EW +PN EN+Q    KKKK+KK+ SPK+ LLN VTIEE+K DD   +  
Sbjct: 844  FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900

Query: 934  RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNL-K 991
              T+ LP +LEEQ++G+++W    PTTFKP+SPDLA+HYKSASPQPAF ++P+TP+++ K
Sbjct: 901  NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960

Query: 992  HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDC------------------------ 1026
            HH+IQELPLDNTFV  CD++S  SS+SSD +S S+C                        
Sbjct: 961  HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSD 1020

Query: 1027 GYPVTTFEVPVSV--HTR-------PSQRRVTFHLPEGSQESSSDGGLGDHD-AGSLTST 1076
              PVT  + P S   H +        SQRRVTFHLP+GSQES SD GLGDH+  GS T  
Sbjct: 1021 NIPVTPQKCPSSTGFHIQENEESHYESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI 1080

Query: 1077 SHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQEC 1136
            SH LPL  PQ+E++D+A+P  RTE DGNSDP S    G +        + EA++ CTQEC
Sbjct: 1081 SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPR-------GLAEATEMCTQEC 1133

Query: 1137 LIYGHSDACWMPASL 1151
            L+ GHSD CWMP  L
Sbjct: 1134 LVLGHSDNCWMPPGL 1148


>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
          Length = 1237

 Score =  692 bits (1785), Expect = 0.0
 Identities = 448/1167 (38%), Positives = 642/1167 (55%), Gaps = 90/1167 (7%)

Query: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
            LL  + + A+LL+       A    Y + EE P N LIG+L  D     + +        
Sbjct: 37   LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88

Query: 95   FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 148
               +YK     P +R++  TG+IFTT   IDRE L  C      + C  E EV+I   + 
Sbjct: 89   ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145

Query: 149  DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 208
            +   RL++ +  ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146  NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205

Query: 209  ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 265
            EL    ++Q +FGL V E  E +K PQLIV   LDRE  D+Y + +KV+DGG P R+S+A
Sbjct: 206  ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264

Query: 266  ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 325
            +L+V+V DTNDN P F+    E  + EN+P+G SV Q+ A D+D G NA+I ++F     
Sbjct: 265  LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323

Query: 326  NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 383
             + RRL  L+  TGLIT++ P+DRE+    +  VLA D G  P  ARA V+V V D+NDN
Sbjct: 324  EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383

Query: 384  VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
             P+I+IR I  V   +    +SE++   T +AL+ V+D+D   N  VTC    ++PF+LR
Sbjct: 384  APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443

Query: 442  PVFSN------QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 495
                       ++ L+    LDYE  K+Y I+++A D+G PPL+ +  L ++V D NDNA
Sbjct: 444  QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503

Query: 496  PVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGM 553
            PVFTQS   V+ PENN PG  + +++A+DADSG NAE+ Y L P+   +  F++   TG 
Sbjct: 504  PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563

Query: 554  LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPE 613
            + V   LDRE+ + Y   ++A D G P L    TV V+++D NDN P F  + Y F V E
Sbjct: 564  IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623

Query: 614  NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 673
            N+P    VG++TV D D G+N+ V LS+  +N DF I + TG I  ++SFDRE+Q +YTF
Sbjct: 624  NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683

Query: 674  YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAV 733
             +KA DGG   RS+   VTINV+D NDN P +I  P N S++L+ P T  G  V QV A 
Sbjct: 684  QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742

Query: 734  DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 793
            D D+G+NAE+ YSI GGN   LF I   +G ITL ++ +    GLHR++VK +D G+P  
Sbjct: 743  DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802

Query: 794  LFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 853
             +   +V+L+VNE++ N TL+  L+  S++ P+  +         +     IL   VAG 
Sbjct: 803  -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861

Query: 854  ITVVVVIFITAVVR-CRQAPHLKAAQKNMQNS-EWATPNPENRQMIMMKKKKKKKKHSPK 911
            + V ++I +  +VR CRQ       Q   + + +   P P  +     K K KK K SPK
Sbjct: 862  VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920

Query: 912  NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 971
             +            +D D  G  +   L  +L     G    +  P  + P SPDL RHY
Sbjct: 921  PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969

Query: 972  KSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPV 1030
            +S SP P+ Q+QP++P  + KH ++Q+LP  NTFV      + +S+ S+ YS  D  Y  
Sbjct: 970  RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT---GDTTSTGSEQYS--DYSYRT 1024

Query: 1031 TTFEVPVSVHTRPSQRRVTF-------HLPEGSQESSSDGGLGDHDAGSLTSTSHGL--P 1081
               + P     +   RRVTF        L + SQ S  D GL + +  S  S+S     P
Sbjct: 1025 NPPKYPSK---QLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGP 1081

Query: 1082 LGYPQEEYFDRATPSNRTEGDGN----SDPESTFIPGLKKEITVQPTVEEASDNCTQECL 1137
            L  P E++++R TP      DG+      PE+   P         P V   +  CT+EC 
Sbjct: 1082 LALP-EDHYERTTP------DGSIGEMEHPENDLRP--------LPDVA-MTGTCTRECS 1125

Query: 1138 IYGHSDACWMPASLDHSSSSQAQASAL 1164
             +GHSD CWMP     S S + ++SAL
Sbjct: 1126 EFGHSDTCWMPG--QSSPSRRTKSSAL 1150


>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
          Length = 1060

 Score =  654 bits (1687), Expect = 0.0
 Identities = 399/1012 (39%), Positives = 571/1012 (56%), Gaps = 51/1012 (5%)

Query: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
            LL  + + A+LL+       A    Y + EE P N LIG+L  D     + +        
Sbjct: 37   LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88

Query: 95   FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 148
               +YK     P +R++  TG+IFTT   IDRE L  C      + C  E EV+I   + 
Sbjct: 89   ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145

Query: 149  DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 208
            +   RL++ +  ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146  NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205

Query: 209  ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 265
            EL    ++Q +FGL V E  E +K PQLIV   LDRE  D+Y + +KV+DGG P R+S+A
Sbjct: 206  ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264

Query: 266  ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 325
            +L+V+V DTNDN P F+    E  + EN+P+G SV Q+ A D+D G NA+I ++F     
Sbjct: 265  LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323

Query: 326  NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 383
             + RRL  L+  TGLIT++ P+DRE+    +  VLA D G  P  ARA V+V V D+NDN
Sbjct: 324  EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383

Query: 384  VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
             P+I+IR I  V   +    +SE++   T +AL+ V+D+D   N  VTC    ++PF+LR
Sbjct: 384  APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443

Query: 442  PVFSN------QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 495
                       ++ L+    LDYE  K+Y I+++A D+G PPL+ +  L ++V D NDNA
Sbjct: 444  QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503

Query: 496  PVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGM 553
            PVFTQS   V+ PENN PG  + +++A+DADSG NAE+ Y L P+   +  F++   TG 
Sbjct: 504  PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563

Query: 554  LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPE 613
            + V   LDRE+ + Y   ++A D G P L    TV V+++D NDN P F  + Y F V E
Sbjct: 564  IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623

Query: 614  NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 673
            N+P    VG++TV D D G+N+ V LS+  +N DF I + TG I  ++SFDRE+Q +YTF
Sbjct: 624  NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683

Query: 674  YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAV 733
             +KA DGG   RS+   VTINV+D NDN P +I  P N S++L+ P T  G  V QV A 
Sbjct: 684  QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742

Query: 734  DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 793
            D D+G+NAE+ YSI GGN   LF I   +G ITL ++ +    GLHR++VK +D G+P  
Sbjct: 743  DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802

Query: 794  LFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 853
             +   +V+L+VNE++ N TL+  L+  S++ P+  +         +     IL   VAG 
Sbjct: 803  -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861

Query: 854  ITVVVVIFITAVVR-CRQAPHLKAAQK-NMQNSEWATPNPENRQMIMMKKKKKKKKHSPK 911
            + V ++I +  +VR CRQ       Q    +  +   P P  +     K K KK K SPK
Sbjct: 862  VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920

Query: 912  NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 971
                 V  +E       D D   +   L  +L     G    +  P  + P SPDL RHY
Sbjct: 921  ----PVKPVE-------DEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969

Query: 972  KSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYS 1022
            +S SP P+ Q+QP++P  + KH ++Q+LP  NTFV     ++  S     YS
Sbjct: 970  RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021


>gi|190194360 protocadherin 20 [Homo sapiens]
          Length = 951

 Score =  623 bits (1606), Expect = e-178
 Identities = 345/820 (42%), Positives = 503/820 (61%), Gaps = 43/820 (5%)

Query: 40  YIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 99
           ++F     C+  +S A E  Y++ E +P  VLIG+L +DL L  +P  +     Q +L  
Sbjct: 50  FLFVGPFSCLGSYSRATELLYSLNEGLPAGVLIGSLAEDLRL--LPRSAGRPDPQSQLPE 107

Query: 100 KTG---DVPL-------------IRIEEDTGEIFTTGARIDREKLC-------------- 129
           +TG   + PL             + ++  +GE+ T+   IDRE LC              
Sbjct: 108 RTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVS 167

Query: 130 -AGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINS 188
            +  P D  C   ++V +LP E FR VK++  I DINDNAP FP + I++ +PEN+ +N+
Sbjct: 168 ISSSPSDS-CLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNT 226

Query: 189 KYTLP-AAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTY 247
           +  +   AVDPDVGINGVQ Y L+    +F LDV E   G++ P LIV   LDRE +D Y
Sbjct: 227 RLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQY 286

Query: 248 VMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD 307
           V  +  EDGG P    +A L + ++D NDN P+F +++I V++  NA VGT +  + A D
Sbjct: 287 VSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVD 346

Query: 308 ADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM 367
            D+G NA+I +S+S  V   ++ LFHL+  TG+I +   +      +HKL +LA+  G +
Sbjct: 347 KDLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCI 406

Query: 368 PARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGR 427
           PA    LV++  V    P I  RYI N ++  V L E  P+NT IA  T+ D +  +  +
Sbjct: 407 PAVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKY--K 464

Query: 428 VTCFTDHEIPFRLRPV--FSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLF 485
           V C+ D E PFRL P   ++N++LLE    +DYE  + Y + ++A ++     +   ++ 
Sbjct: 465 VNCYLDGEGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIK 522

Query: 486 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEF 545
           +++ D+NDNAP+F Q  + ++I ENNSP   L K+ ATDADS    +++Y LGPDAP  F
Sbjct: 523 VQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYF 582

Query: 546 SLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHN 605
           SLD  TG+LTV  +LDRE+++KY +T+ A D G PP  S  TV ++++D+NDNSP F + 
Sbjct: 583 SLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINK 642

Query: 606 EYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDR 665
           ++ F+VPEN P +G +G+I+VTD D G N  V LS+++++D F ID+  G++R  +S DR
Sbjct: 643 DFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDR 702

Query: 666 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGT 725
           E+Q SYT +V+A DGG  + SS+AK+TI ++D+NDN P+ + P  N SY LVLPST PG+
Sbjct: 703 EQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGS 762

Query: 726 VVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLV 783
            V +V AVD DTGMNA + YSI+G  G   + F ID +TGNITL E    TD GLHR+LV
Sbjct: 763 PVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLV 822

Query: 784 KANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIE 823
           K +D G P+ L S V+VNLFVN++V+N + I  L+RK  E
Sbjct: 823 KVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPE 862


>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
          Length = 1200

 Score =  615 bits (1585), Expect = e-175
 Identities = 410/1123 (36%), Positives = 608/1123 (54%), Gaps = 87/1123 (7%)

Query: 60   YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
            Y + EE P +V IGN+  DL +       +T + +     ++G    ++I+  TGE+ T+
Sbjct: 36   YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87

Query: 120  GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175
              RIDREKL  C  I  +  CF + EV+++ P + +  L + + ++ DINDN P FP+ V
Sbjct: 88   ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147

Query: 176  INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 225
            + +++ EN  + + Y LP A D D G NG++ YEL++          S+     D    P
Sbjct: 148  LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207

Query: 226  EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 284
             G             +   D          GG   RSS   LQV+ T   +  P +  + 
Sbjct: 208  GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264

Query: 285  EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 344
              E  + EN+  GT + QL A D D+G N +I + F     ++ RRL  L+ T+G +++ 
Sbjct: 265  VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323

Query: 345  EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 401
              +DREE    +  V+A D G  P   +A V++N+ D NDNVPSI+IR I   P+ D V 
Sbjct: 324  HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383

Query: 402  -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENA 453
             ++E++ ++T IAL+ V+D+D   NG VTC    ++PF+L+P    +       + L  +
Sbjct: 384  NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443

Query: 454  AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 513
              LDYE+T+E+ + ++A D+G P L+ +  L +KV D NDN P+F QS V V  PENN P
Sbjct: 444  TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503

Query: 514  GIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 573
            G ++  V ATDADSG NAEI Y L       F++D  +G + V   LDRE+ D+Y F + 
Sbjct: 504  GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563

Query: 574  AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGD 633
            AKD G+P L  + TV V + D+NDN P F  + + FYV ENL  +  VG++TV D D G 
Sbjct: 564  AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623

Query: 634  NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 693
            N+ ++L I + N+ F+I++ TG I   +SFDRE Q +YTF VKA DGG   RS++A V++
Sbjct: 624  NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683

Query: 694  NVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 753
             V+D NDN P  +  P N SY L+ PS+N  TVV  V+A D+D G+NA++ YSIVGGN  
Sbjct: 684  FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742

Query: 754  DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 813
             LF ID  +G ++L+ K      GLHR++V+ ND GQP S  +  +V++FVNESV+NAT 
Sbjct: 743  KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801

Query: 814  INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 872
            I+  + +S+  P+T +         +   + I++  VAG +TV+++I I  + R CR   
Sbjct: 802  IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861

Query: 873  HLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDG 932
                      + ++ TP   ++     K KK KK   P  L  ++VT+E +K +    D 
Sbjct: 862  KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919

Query: 933  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLK 991
                L      +  +MG+Y  V       P SPDLARHYKS+SP P  Q+ P++P    K
Sbjct: 920  VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970

Query: 992  HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRPSQRRVT 1049
            H  +Q+LP  NTFV A D+IS  S   S+    ++  Y    F  V  SV ++P      
Sbjct: 971  HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQDPH-- 1028

Query: 1050 FHLPEGSQESSSDGGLGDHDAGSLTSTS----HGLPLGYPQEEYFDRATPSNRTEGDGNS 1105
                +GS +S  D GL + +  S  S+S      LPL    E+ ++R TP      DG+ 
Sbjct: 1029 ----QGSLQSCYDSGLEESETPSSKSSSGPRLGALPL---PEDNYERTTP------DGSV 1075

Query: 1106 DPESTFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDACWMP 1148
            D  S  +P +             +  CT+EC  YGHSD+CWMP
Sbjct: 1076 D--SRPLPDV-----------ALTGKCTRECDEYGHSDSCWMP 1105


>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
          Length = 1072

 Score =  607 bits (1564), Expect = e-173
 Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%)

Query: 60   YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
            Y + EE P +V IGN+  DL +       +T + +     ++G    ++I+  TGE+ T+
Sbjct: 36   YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87

Query: 120  GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175
              RIDREKL  C  I  +  CF + EV+++ P + +  L + + ++ DINDN P FP+ V
Sbjct: 88   ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147

Query: 176  INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 225
            + +++ EN  + + Y LP A D D G NG++ YEL+          +S+     D    P
Sbjct: 148  LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207

Query: 226  EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 250
             G                                 + +L V    D E++   ++K    
Sbjct: 208  GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267

Query: 251  ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300
                      ++V DGG P RSS AIL+V +TD NDN P F+++  E  + EN+  GT +
Sbjct: 268  REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327

Query: 301  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360
             QL A D D+G N +I + F     ++ RRL  L+ T+G +++   +DREE    +  V+
Sbjct: 328  LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386

Query: 361  ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 416
            A D G  P   +A V++N+ D NDNVPSI+IR I   P+ D V  ++E++ ++T IAL+ 
Sbjct: 387  ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446

Query: 417  VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 469
            V+D+D   NG VTC    ++PF+L+P    +       + L  +  LDYE+T+E+ + ++
Sbjct: 447  VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506

Query: 470  AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529
            A D+G P L+ +  L +KV D NDN P+F QS V V  PENN PG ++  V ATDADSG 
Sbjct: 507  AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566

Query: 530  NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 589
            NAEI Y L       F++D  +G + V   LDRE+ D+Y F + AKD G+P L  + TV 
Sbjct: 567  NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626

Query: 590  VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 649
            V + D+NDN P F  + + FYV ENL  +  VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627  VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686

Query: 650  IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 709
            I++ TG I   +SFDRE Q +YTF VKA DGG   RS++A V++ V+D NDN P  +  P
Sbjct: 687  IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745

Query: 710  YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 769
             N SY L+ PS+N  TVV  V+A D+D G+NA++ YSIVGGN   LF ID  +G ++L+ 
Sbjct: 746  KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805

Query: 770  KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829
            K      GLHR++V+ ND GQP S  +  +V++FVNESV+NAT I+  + +S+  P+T +
Sbjct: 806  KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864

Query: 830  TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 888
                     +   + I++  VAG +TV+++I I  + R CR             + ++ T
Sbjct: 865  IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924

Query: 889  PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 948
            P   ++     K KK KK   P  L  ++VT+E +K +    D     L      +  +M
Sbjct: 925  PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977

Query: 949  GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 1006
            G+Y  V       P SPDLARHYKS+SP P  Q+ P++P    KH  +Q+LP  NTFV A
Sbjct: 978  GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033

Query: 1007 CDSISNCSSSSSD 1019
             D+IS  S   S+
Sbjct: 1034 GDNISIGSDHCSE 1046


>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
          Length = 1069

 Score =  607 bits (1564), Expect = e-173
 Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%)

Query: 60   YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
            Y + EE P +V IGN+  DL +       +T + +     ++G    ++I+  TGE+ T+
Sbjct: 36   YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87

Query: 120  GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 175
              RIDREKL  C  I  +  CF + EV+++ P + +  L + + ++ DINDN P FP+ V
Sbjct: 88   ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147

Query: 176  INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 225
            + +++ EN  + + Y LP A D D G NG++ YEL+          +S+     D    P
Sbjct: 148  LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207

Query: 226  EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 250
             G                                 + +L V    D E++   ++K    
Sbjct: 208  GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267

Query: 251  ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 300
                      ++V DGG P RSS AIL+V +TD NDN P F+++  E  + EN+  GT +
Sbjct: 268  REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327

Query: 301  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 360
             QL A D D+G N +I + F     ++ RRL  L+ T+G +++   +DREE    +  V+
Sbjct: 328  LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386

Query: 361  ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 416
            A D G  P   +A V++N+ D NDNVPSI+IR I   P+ D V  ++E++ ++T IAL+ 
Sbjct: 387  ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446

Query: 417  VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 469
            V+D+D   NG VTC    ++PF+L+P    +       + L  +  LDYE+T+E+ + ++
Sbjct: 447  VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506

Query: 470  AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529
            A D+G P L+ +  L +KV D NDN P+F QS V V  PENN PG ++  V ATDADSG 
Sbjct: 507  AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566

Query: 530  NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 589
            NAEI Y L       F++D  +G + V   LDRE+ D+Y F + AKD G+P L  + TV 
Sbjct: 567  NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626

Query: 590  VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 649
            V + D+NDN P F  + + FYV ENL  +  VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627  VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686

Query: 650  IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 709
            I++ TG I   +SFDRE Q +YTF VKA DGG   RS++A V++ V+D NDN P  +  P
Sbjct: 687  IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745

Query: 710  YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 769
             N SY L+ PS+N  TVV  V+A D+D G+NA++ YSIVGGN   LF ID  +G ++L+ 
Sbjct: 746  KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805

Query: 770  KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829
            K      GLHR++V+ ND GQP S  +  +V++FVNESV+NAT I+  + +S+  P+T +
Sbjct: 806  KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864

Query: 830  TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 888
                     +   + I++  VAG +TV+++I I  + R CR             + ++ T
Sbjct: 865  IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924

Query: 889  PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 948
            P   ++     K KK KK   P  L  ++VT+E +K +    D     L      +  +M
Sbjct: 925  PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977

Query: 949  GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 1006
            G+Y  V       P SPDLARHYKS+SP P  Q+ P++P    KH  +Q+LP  NTFV A
Sbjct: 978  GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033

Query: 1007 CDSISNCSSSSSD 1019
             D+IS  S   S+
Sbjct: 1034 GDNISIGSDHCSE 1046


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  365 bits (937), Expect = e-100
 Identities = 235/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)

Query: 44  VLLVCVVF----HSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 99
           ++L+C+ F     +GA++ +Y+I EE+ +   +GN+ KDL L+  P +     ++   + 
Sbjct: 17  LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71

Query: 100 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 159
             G   L  +   +G + T G RIDRE+LCA   R   C   V   IL ++  +L  I  
Sbjct: 72  SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125

Query: 160 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 219
            + DINDNAP F A  +++ I EN A   ++ LP A+DPDVG+N +Q+Y+L  +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184

Query: 220 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 279
            V     G K P+L+++  LDREE+  + + +   DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244

Query: 280 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 339
           VF   E  VS+PEN PVGT +  + ATD D G N ++ +SF  L      + F LN  TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303

Query: 340 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 399
            I I E LD EET  +++ + A DGG   A A VL+ V DVNDN P + I  + +PV   
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360

Query: 400 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 459
              +E+ PL T +AL+ V D D++ NG+VTC     +PF+L     + + L     LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417

Query: 460 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK 519
               Y I + A D G PPL+  A   ++V D NDN P F+Q      IPENN+ G  +  
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477

Query: 520 VSATDADSGPNAEINYLLGPDA------PPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 573
           V+A D DS  NA+I Y L  D           S++  TG+L  ++  D E+  +    + 
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537

Query: 574 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------- 623
           A D+G PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+          
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589

Query: 624 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 676
                +   D D G N+ ++  +L  ++   F +   TG +R   +         +  V 
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649

Query: 677 AEDGGRVSRSSSAKVTINVVD 697
            +D G+   S++  +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670



 Score =  242 bits (618), Expect = 2e-63
 Identities = 197/670 (29%), Positives = 312/670 (46%), Gaps = 71/670 (10%)

Query: 233 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 286
           LI    +DREE      +      + VED     R     +++ VTD NDN P F+   +
Sbjct: 88  LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142

Query: 287 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 346
           +V I EN   G       A D D+G N+   +  S        + F L   +    +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196

Query: 347 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 397
                  LDREE   H L++ ASDGG  L     +V V V D NDN P   +        
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251

Query: 398 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP------FRLRPVFSNQFLLE 451
             V + EN+P+ T++  +T TD+D   NG VT ++  ++P      F+L        + E
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309

Query: 452 NAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 511
           N   LDYE T  Y I++ A D G      +A + I V+D NDN+P  T + +   + E++
Sbjct: 310 N---LDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDS 364

Query: 512 SPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGM---LTVVKKLDREKEDKY 568
             G  +  ++  D DS  N ++   +    P  F L++       L + + LDRE+   Y
Sbjct: 365 PLGTVVALLNVHDLDSEQNGQVTCSILAYLP--FKLEKSIDSYYRLVIHRALDREQVSSY 422

Query: 569 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTD 628
             T+ A D G PPL++     + + D NDN P F+   Y  Y+PEN  R  ++  +T  D
Sbjct: 423 NITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALD 482

Query: 629 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
           PD  +N+ +  S+ ++       +   +I+S TGV+    SFD E+       V A D G
Sbjct: 483 PDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSG 542

Query: 682 RVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDT 737
               SS+  +++ V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+
Sbjct: 543 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 602

Query: 738 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 797
           G NA + Y ++  +   LFA+ + TG +         D     ++V   D GQP  L + 
Sbjct: 603 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSAT 661

Query: 798 VIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 857
           V + + V +S+    ++ +L   S E+P   N+E +D++     Y+ + VAAV+      
Sbjct: 662 VTLTVAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAF 711

Query: 858 VVIFITAVVR 867
           V++ +   +R
Sbjct: 712 VIVLLAHRLR 721



 Score =  108 bits (270), Expect = 3e-23
 Identities = 93/306 (30%), Positives = 137/306 (44%), Gaps = 30/306 (9%)

Query: 545 FSLDRRTGMLTVVKKLDREK------EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDN 598
           FSL+ R+G L    ++DRE+           F IL +D           + + + D NDN
Sbjct: 79  FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDR-----VKLFGIEIEVTDINDN 133

Query: 599 SPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQT---G 655
           +P F        + EN+       L    DPD G NS  +   L  N  F++  Q+   G
Sbjct: 134 APKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQ-LSPNKHFSLRVQSRANG 192

Query: 656 VIRPNI----SFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN 711
           V  P +    S DRE++  +   + A DGG   RS +  V++ V D NDN PVF +P Y 
Sbjct: 193 VKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYR 252

Query: 712 YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL--FAIDQETGNITLME 769
            S    LP    GT +  V A D D G N EV YS        L  F +++ TG I + E
Sbjct: 253 VSVPENLP---VGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISE 309

Query: 770 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829
             D  + G + + ++A D G   +   V+I    VN++        EL   S+ +PVT +
Sbjct: 310 NLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSP------ELTITSLFSPVTED 363

Query: 830 TEIADV 835
           + +  V
Sbjct: 364 SPLGTV 369


>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
           [Homo sapiens]
          Length = 850

 Score =  365 bits (937), Expect = e-100
 Identities = 235/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)

Query: 44  VLLVCVVF----HSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 99
           ++L+C+ F     +GA++ +Y+I EE+ +   +GN+ KDL L+  P +     ++   + 
Sbjct: 17  LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71

Query: 100 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 159
             G   L  +   +G + T G RIDRE+LCA   R   C   V   IL ++  +L  I  
Sbjct: 72  SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125

Query: 160 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 219
            + DINDNAP F A  +++ I EN A   ++ LP A+DPDVG+N +Q+Y+L  +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184

Query: 220 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 279
            V     G K P+L+++  LDREE+  + + +   DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244

Query: 280 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 339
           VF   E  VS+PEN PVGT +  + ATD D G N ++ +SF  L      + F LN  TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303

Query: 340 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 399
            I I E LD EET  +++ + A DGG   A A VL+ V DVNDN P + I  + +PV   
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360

Query: 400 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 459
              +E+ PL T +AL+ V D D++ NG+VTC     +PF+L     + + L     LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417

Query: 460 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK 519
               Y I + A D G PPL+  A   ++V D NDN P F+Q      IPENN+ G  +  
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477

Query: 520 VSATDADSGPNAEINYLLGPDA------PPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 573
           V+A D DS  NA+I Y L  D           S++  TG+L  ++  D E+  +    + 
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537

Query: 574 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------- 623
           A D+G PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+          
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589

Query: 624 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 676
                +   D D G N+ ++  +L  ++   F +   TG +R   +         +  V 
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649

Query: 677 AEDGGRVSRSSSAKVTINVVD 697
            +D G+   S++  +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670



 Score =  242 bits (618), Expect = 2e-63
 Identities = 197/670 (29%), Positives = 312/670 (46%), Gaps = 71/670 (10%)

Query: 233 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 286
           LI    +DREE      +      + VED     R     +++ VTD NDN P F+   +
Sbjct: 88  LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142

Query: 287 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 346
           +V I EN   G       A D D+G N+   +  S        + F L   +    +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196

Query: 347 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 397
                  LDREE   H L++ ASDGG  L     +V V V D NDN P   +        
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251

Query: 398 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP------FRLRPVFSNQFLLE 451
             V + EN+P+ T++  +T TD+D   NG VT ++  ++P      F+L        + E
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309

Query: 452 NAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 511
           N   LDYE T  Y I++ A D G      +A + I V+D NDN+P  T + +   + E++
Sbjct: 310 N---LDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDS 364

Query: 512 SPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGM---LTVVKKLDREKEDKY 568
             G  +  ++  D DS  N ++   +    P  F L++       L + + LDRE+   Y
Sbjct: 365 PLGTVVALLNVHDLDSEQNGQVTCSILAYLP--FKLEKSIDSYYRLVIHRALDREQVSSY 422

Query: 569 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTD 628
             T+ A D G PPL++     + + D NDN P F+   Y  Y+PEN  R  ++  +T  D
Sbjct: 423 NITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALD 482

Query: 629 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
           PD  +N+ +  S+ ++       +   +I+S TGV+    SFD E+       V A D G
Sbjct: 483 PDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSG 542

Query: 682 RVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDT 737
               SS+  +++ V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+
Sbjct: 543 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 602

Query: 738 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 797
           G NA + Y ++  +   LFA+ + TG +         D     ++V   D GQP  L + 
Sbjct: 603 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSAT 661

Query: 798 VIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 857
           V + + V +S+    ++ +L   S E+P   N+E +D++     Y+ + VAAV+      
Sbjct: 662 VTLTVAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAF 711

Query: 858 VVIFITAVVR 867
           V++ +   +R
Sbjct: 712 VIVLLAHRLR 721



 Score =  108 bits (270), Expect = 3e-23
 Identities = 93/306 (30%), Positives = 137/306 (44%), Gaps = 30/306 (9%)

Query: 545 FSLDRRTGMLTVVKKLDREK------EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDN 598
           FSL+ R+G L    ++DRE+           F IL +D           + + + D NDN
Sbjct: 79  FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDR-----VKLFGIEIEVTDINDN 133

Query: 599 SPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQT---G 655
           +P F        + EN+       L    DPD G NS  +   L  N  F++  Q+   G
Sbjct: 134 APKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQ-LSPNKHFSLRVQSRANG 192

Query: 656 VIRPNI----SFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN 711
           V  P +    S DRE++  +   + A DGG   RS +  V++ V D NDN PVF +P Y 
Sbjct: 193 VKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYR 252

Query: 712 YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL--FAIDQETGNITLME 769
            S    LP    GT +  V A D D G N EV YS        L  F +++ TG I + E
Sbjct: 253 VSVPENLP---VGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISE 309

Query: 770 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 829
             D  + G + + ++A D G   +   V+I    VN++        EL   S+ +PVT +
Sbjct: 310 NLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSP------ELTITSLFSPVTED 363

Query: 830 TEIADV 835
           + +  V
Sbjct: 364 SPLGTV 369


>gi|14589929 protocadherin 18 precursor [Homo sapiens]
          Length = 1135

 Score =  360 bits (924), Expect = 5e-99
 Identities = 226/660 (34%), Positives = 360/660 (54%), Gaps = 27/660 (4%)

Query: 40  YIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLN--LSLIPNKSLTTTMQFKL 97
           ++FA+L+V        +   Y I EE     +I  L +D+   L  +PN S   T++F+ 
Sbjct: 12  FVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPS---TVRFRA 68

Query: 98  VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 157
           + + G+ PL+ + ED GEI + GA IDRE+LC    ++ +C  E +V  LP E  +L  I
Sbjct: 69  MQR-GNSPLLVVNEDNGEI-SIGATIDREQLCQ---KNLNCSIEFDVITLPTEHLQLFHI 123

Query: 158 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 217
              + DINDN+P F  ++I I I E++A+ ++  L +A DPDVG N +  Y L  + + F
Sbjct: 124 EVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSL-SANDFF 182

Query: 218 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 277
            ++V    +G K  +LIV +ELDRE K +Y +++   D G PQRS ++IL++S++D+NDN
Sbjct: 183 NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDN 242

Query: 278 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 337
            P F++    + + EN+PVGT +  L+ATD D G N KI +SFS+ VS      F +++ 
Sbjct: 243 SPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSE 302

Query: 338 TGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNP 395
            G +T+ + +D E T ++++ V A D G   +PA   +++ V DVNDN P I+I  +   
Sbjct: 303 RGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPG 362

Query: 396 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 455
             +   + E  P++T +AL+ V DKD+  NG + C       F+L+  + N +L+   A 
Sbjct: 363 KEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNAT 422

Query: 456 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 515
           LD E   EY++ ++A D G P L+      +++ D NDN P F +S     I ENNSPG 
Sbjct: 423 LDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGA 482

Query: 516 QLMKVSATDADSGPNAEINY------LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYL 569
            +  V+ATD D G N ++ Y      +LG       ++D   G +  ++  D E+  +  
Sbjct: 483 YITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQIT 542

Query: 570 FTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPV-----FTHNEYKFYVPENLPRHGTVGL 623
           F + A+D G P  L SN TV ++IID+NDN PV       +N  +  +P+       V  
Sbjct: 543 FVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTR 602

Query: 624 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
           I   D D G N+ ++ +I+  N++  F ID ++  I  N+S D      +   V  +D G
Sbjct: 603 IRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKG 662



 Score =  247 bits (631), Expect = 5e-65
 Identities = 241/908 (26%), Positives = 371/908 (40%), Gaps = 122/908 (13%)

Query: 267  LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVS 325
            ++V V D NDN P F  + I + I E+A VGT +    A D D+GEN+   +S S N   
Sbjct: 123  IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFF 182

Query: 326  NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARA---MVLVNVTDVND 382
            NI  R     A    + +   LDRE   +++L + ASD G+ P R+   ++ ++++D ND
Sbjct: 183  NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGV-PQRSGSSILKISISDSND 241

Query: 383  NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-CFTDHEIPFRLR 441
            N P+ + +  +      + L EN P+ T +  +  TD D   NG++   F+ H  P  + 
Sbjct: 242  NSPAFEQQSYI------IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIME 295

Query: 442  P--VFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFT 499
               + S +  L     +DYE TK Y I + A D G   +     + IKV D NDN P   
Sbjct: 296  TFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEIN 355

Query: 500  QSFVTVS------IPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGM 553
             + ++        I E +     +  V   D DSG N EI   L      +         
Sbjct: 356  INLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNY 415

Query: 554  LTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVP 612
            L +    LDREK  +Y  T++A+D G P L++     V I D NDN P F  + Y+F + 
Sbjct: 416  LILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVIS 475

Query: 613  ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 665
            EN      +  +T TDPD G+N  VT +IL+            TID   G I     FD 
Sbjct: 476  ENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDH 535

Query: 666  EKQESYTFYVKAEDGGRVSRS-SSAKVTINVVDVNDNKPVFIVPPY-NYSYELVLPS-TN 722
            E+    TF V+A DGG   +  S+  V + ++D NDN PV I P   N + E+ +P    
Sbjct: 536  EEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAE 595

Query: 723  PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 782
             G  V ++ A+D D+G+NAE+  +IV GN  ++F ID  + +I      D        + 
Sbjct: 596  SGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELS 655

Query: 783  VKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDY 842
            V   D G P  L + V++   + E   + T                +T +  VS  + D 
Sbjct: 656  VIIQDKGNP-QLHTKVLLKCMIFEYAESVT----------------STAMTSVSQASLDV 698

Query: 843  VKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKK 902
              I++ ++     V++VI +    RC           N +  +  + N    +       
Sbjct: 699  SMIIIISLGAICAVLLVIMVLFATRC-----------NREKKDTRSYNCRVAESTYQHHP 747

Query: 903  KKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKP 962
            K+  +   K  +  V TI  T               LPI    ++       ++PT  + 
Sbjct: 748  KRPSRQIHKGDITLVPTINGT---------------LPIRSHHRSSPS----SSPTLERG 788

Query: 963  DSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFV--ACDSISNCSSSSSDP 1020
                   H    S      I         +H+ +   L+ T    A + +S   S     
Sbjct: 789  QMGSRQSHNSHQSLNSLVTIS-------SNHVPENFSLELTHATPAVEQVSQLLSMLHQ- 840

Query: 1021 YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL 1080
                        ++   S       R   + L +  + S  D G GD +AG         
Sbjct: 841  ----------GQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGD-------- 882

Query: 1081 PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG 1140
                  +    R +P +R  G+G SD   T              +  A   CT+EC + G
Sbjct: 883  -----SDYDLGRDSPIDRLLGEGFSDLFLT-----------DGRIPAAMRLCTEECRVLG 926

Query: 1141 HSDACWMP 1148
            HSD CWMP
Sbjct: 927  HSDQCWMP 934


>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
          Length = 1101

 Score =  355 bits (911), Expect = 2e-97
 Identities = 235/669 (35%), Positives = 362/669 (54%), Gaps = 36/669 (5%)

Query: 44  VLLVCVVFHSGAQEKN--YTIREEIPENVLIGNLLKDLN---LSLIPNKSLTTTMQFKLV 98
           +LL+ +++   A   N  Y++ EE     +I N+ KD      +L P ++      F++V
Sbjct: 9   LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA----FRVV 64

Query: 99  YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 158
             +    L+ I   +G +  T  +IDR+ LC   P+   C   +EV     EI  ++K+ 
Sbjct: 65  SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118

Query: 159 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 218
             I+D+NDNAP FPA  I + I E ++  ++  L +A DPD G  GVQ YEL  ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175

Query: 219 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 278
           L++    +G +  +L+V+K LDRE +  Y  ++   DGG P R  T  L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235

Query: 279 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 338
           PVF E+   VS+PEN+P  T V +L+A+D D G N ++ +SF   V++  R LF ++  +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295

Query: 339 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 396
           GL+T+   LD EE   ++L V A D G   +PA   V V+V D NDN P I+   +++  
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352

Query: 397 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYL 456
           ++ V +SE+ P    IAL+ V+D+D+  NGRV C     +PFRL+   S   +L +   L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGR-L 411

Query: 457 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 516
           D E   +Y + + A D G P L  +    + + DENDN P F++ +  V + ENN+PG  
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471

Query: 517 LMKVSATDADSGPNAEINYLLGP----DAP--PEFSLDRRTGMLTVVKKLDREKEDKYLF 570
           L+ VSA D D G N  ++Y + P    D P     S++  +G +  ++  + E+   + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531

Query: 571 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYKFYVPENLPRHGTVGLIT 625
            +LAKD G+P L SN TV V I+D NDN+PV T     +   + Y+P N      V ++ 
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591

Query: 626 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 684
             D D G+N  VT  + + +   F ID   G +R   +F    + SY   V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651

Query: 685 RSSSAKVTI 693
            S+SA V I
Sbjct: 652 LSASALVLI 660



 Score =  225 bits (573), Expect = 3e-58
 Identities = 243/949 (25%), Positives = 388/949 (40%), Gaps = 136/949 (14%)

Query: 233  LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 292
            L+ ++++DR+       K  +            +++V + D NDN P F   +IE+ I E
Sbjct: 81   LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140

Query: 293  NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 345
             A  GT +    A D D G      +  +         LF L   T         + +++
Sbjct: 141  AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194

Query: 346  PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 403
             LDRE   ++   + A DGG  P    V   + VTD NDN P      + +     V + 
Sbjct: 195  SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248

Query: 404  ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYES 460
            EN P NT +  +  +D D   NG+V       +  R R +F    +  L+     LDYE 
Sbjct: 249  ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308

Query: 461  TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 517
               Y + + A D G   +     + + V D NDN PV     V    V + E+  PG  +
Sbjct: 309  GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368

Query: 518  MKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDN 577
              V  +D DSG N  +   L  + P           + V  +LDRE+ D+Y  TI A+D 
Sbjct: 369  ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428

Query: 578  GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV 637
            GVP L S  +  V I D+NDN P F+   Y+  V EN      +  ++  DPD G N +V
Sbjct: 429  GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488

Query: 638  TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 690
            +  I+             +I+  +G I    SF+ E+ +++ F V A+DGG  S  S+A 
Sbjct: 489  SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548

Query: 691  VTINVVDVNDNKPVFIVPP-YNYSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 748
            V + ++DVNDN PV   PP  N + E+ +P ++  G +V  V A D D G N  V Y + 
Sbjct: 549  VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608

Query: 749  GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 808
             G+ R  F IDQ  G +        +    + ++V A+D G+  SL +  +V ++++ ++
Sbjct: 609  EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666

Query: 809  TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 868
                                    A  S  + +   I + A+     ++ V  I   ++C
Sbjct: 667  D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703

Query: 869  RQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDV 928
            ++  + +    N + +E++  +         KK  KKKK S  ++ L    +EET   +V
Sbjct: 704  KR-DNKEIRTYNCRIAEYSYGH--------QKKSSKKKKISKNDIRLVPRDVEETDKMNV 754

Query: 929  DSDGNRVTLDLPIDLEEQTM--------GKYNWVTTPTTFKPDSPDLARH-YKSASPQPA 979
             S  +  +     D  +QT+          +  V    T    +  +  H + S  PQ  
Sbjct: 755  VSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQ-- 812

Query: 980  FQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSV 1039
               QP+        II  +PL  T               + YS  D  Y        V+ 
Sbjct: 813  ---QPDL-------IINGVPLPET---------------ENYSF-DSNY--------VNS 838

Query: 1040 HTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRT 1099
                 +   TF   EG+  S  D G   H+    T + H +     +  Y D A      
Sbjct: 839  RAHLIKSSSTFKDLEGN--SLKDSG---HEESDQTDSEHDV----QRSLYCDTAV----- 884

Query: 1100 EGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDACWMP 1148
                 +D  +T +  +  ++      +    +C +EC I GHSD CWMP
Sbjct: 885  -----NDVLNTSVTSMGSQMPDHD--QNEGFHCREECRILGHSDRCWMP 926


>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
          Length = 1100

 Score =  355 bits (911), Expect = 2e-97
 Identities = 235/669 (35%), Positives = 362/669 (54%), Gaps = 36/669 (5%)

Query: 44  VLLVCVVFHSGAQEKN--YTIREEIPENVLIGNLLKDLN---LSLIPNKSLTTTMQFKLV 98
           +LL+ +++   A   N  Y++ EE     +I N+ KD      +L P ++      F++V
Sbjct: 9   LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA----FRVV 64

Query: 99  YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 158
             +    L+ I   +G +  T  +IDR+ LC   P+   C   +EV     EI  ++K+ 
Sbjct: 65  SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118

Query: 159 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 218
             I+D+NDNAP FPA  I + I E ++  ++  L +A DPD G  GVQ YEL  ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175

Query: 219 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 278
           L++    +G +  +L+V+K LDRE +  Y  ++   DGG P R  T  L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235

Query: 279 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 338
           PVF E+   VS+PEN+P  T V +L+A+D D G N ++ +SF   V++  R LF ++  +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295

Query: 339 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 396
           GL+T+   LD EE   ++L V A D G   +PA   V V+V D NDN P I+   +++  
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352

Query: 397 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYL 456
           ++ V +SE+ P    IAL+ V+D+D+  NGRV C     +PFRL+   S   +L +   L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGR-L 411

Query: 457 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 516
           D E   +Y + + A D G P L  +    + + DENDN P F++ +  V + ENN+PG  
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471

Query: 517 LMKVSATDADSGPNAEINYLLGP----DAP--PEFSLDRRTGMLTVVKKLDREKEDKYLF 570
           L+ VSA D D G N  ++Y + P    D P     S++  +G +  ++  + E+   + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531

Query: 571 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYKFYVPENLPRHGTVGLIT 625
            +LAKD G+P L SN TV V I+D NDN+PV T     +   + Y+P N      V ++ 
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591

Query: 626 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 684
             D D G+N  VT  + + +   F ID   G +R   +F    + SY   V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651

Query: 685 RSSSAKVTI 693
            S+SA V I
Sbjct: 652 LSASALVLI 660



 Score =  224 bits (572), Expect = 3e-58
 Identities = 245/949 (25%), Positives = 388/949 (40%), Gaps = 137/949 (14%)

Query: 233  LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 292
            L+ ++++DR+       K  +            +++V + D NDN P F   +IE+ I E
Sbjct: 81   LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140

Query: 293  NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 345
             A  GT +    A D D G      +  +         LF L   T         + +++
Sbjct: 141  AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194

Query: 346  PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 403
             LDRE   ++   + A DGG  P    V   + VTD NDN P      + +     V + 
Sbjct: 195  SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248

Query: 404  ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYES 460
            EN P NT +  +  +D D   NG+V       +  R R +F    +  L+     LDYE 
Sbjct: 249  ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308

Query: 461  TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 517
               Y + + A D G   +     + + V D NDN PV     V    V + E+  PG  +
Sbjct: 309  GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368

Query: 518  MKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDN 577
              V  +D DSG N  +   L  + P           + V  +LDRE+ D+Y  TI A+D 
Sbjct: 369  ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428

Query: 578  GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV 637
            GVP L S  +  V I D+NDN P F+   Y+  V EN      +  ++  DPD G N +V
Sbjct: 429  GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488

Query: 638  TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 690
            +  I+             +I+  +G I    SF+ E+ +++ F V A+DGG  S  S+A 
Sbjct: 489  SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548

Query: 691  VTINVVDVNDNKPVFIVPP-YNYSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 748
            V + ++DVNDN PV   PP  N + E+ +P ++  G +V  V A D D G N  V Y + 
Sbjct: 549  VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608

Query: 749  GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 808
             G+ R  F IDQ  G +        +    + ++V A+D G+  SL +  +V ++++ ++
Sbjct: 609  EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666

Query: 809  TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 868
                                    A  S  + +   I + A+     ++ V  I   ++C
Sbjct: 667  D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703

Query: 869  RQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDV 928
            ++  + +    N + +E++  +         KK  KKKK S  ++ L    +EET   +V
Sbjct: 704  KR-DNKEIRTYNCRIAEYSYGH--------QKKSSKKKKISKNDIRLVPRDVEETDKMNV 754

Query: 929  DSDGNRVTLDLPIDLEEQTM--------GKYNWVTTPTTFKPDSPDLARH-YKSASPQPA 979
             S  +  +     D  +QT+          +  V    T    +  +  H + S  PQ  
Sbjct: 755  VSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQ-- 812

Query: 980  FQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSV 1039
               QP+        II  +PL  T               + YS  D  Y      V    
Sbjct: 813  ---QPDL-------IINGVPLPET---------------ENYSF-DSNY------VNSRA 840

Query: 1040 HTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGLPLGYPQEEYFDRATPSNRT 1099
            H   S    TF   EG+  S  D G   H+    T + H +     +  Y D A      
Sbjct: 841  HLIKSS---TFKDLEGN--SLKDSG---HEESDQTDSEHDV----QRSLYCDTAV----- 883

Query: 1100 EGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDACWMP 1148
                 +D  +T +  +  ++      +    +C +EC I GHSD CWMP
Sbjct: 884  -----NDVLNTSVTSMGSQMPDHD--QNEGFHCREECRILGHSDRCWMP 925


>gi|94538350 protocadherin 17 precursor [Homo sapiens]
          Length = 1159

 Score =  355 bits (910), Expect = 2e-97
 Identities = 241/699 (34%), Positives = 366/699 (52%), Gaps = 51/699 (7%)

Query: 59  NYTIREEIPENVLIGNLLKDLNLS--LIPNK----SLTTTMQFKLVYKTGDVPLIRIEED 112
           NY++ EE     +IGN+ +D  L   L P +      + +  ++++  +    L+ ++ D
Sbjct: 22  NYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP-HLLDVDAD 80

Query: 113 TGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFP 172
           +G ++T   RIDRE LC     +  C   +EV     EI  ++K+   I+DINDNAP F 
Sbjct: 81  SGLLYTK-QRIDRESLCR---HNAKCQLSLEVFANDKEIC-MIKVE--IQDINDNAPSFS 133

Query: 173 ATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN-IFGLDVIETPEGDKMP 231
           +  I + I EN+A  +++ L +A DPD G NG++ Y L +  + +FGLDV    +G K P
Sbjct: 134 SDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFP 193

Query: 232 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 291
           +L++QK LDRE+++ + + +   DGG P RS+T  + V V D+NDN PVF+     V +P
Sbjct: 194 ELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELP 253

Query: 292 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 351
           ENAP+GT V  L+ATDAD G N ++ +SFS+ V +  R LF ++  TGLI +K  LD EE
Sbjct: 254 ENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEE 313

Query: 352 TPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLN 409
               ++ V A D G   +PA   V V + D NDN PSI    +         LSE  P  
Sbjct: 314 NGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG-----ALSEAAPPG 368

Query: 410 TKIALITVTDKDADHNGRVTCFT---------------DHEIPFRLRPVFSNQFLLENAA 454
           T IAL+ VTD+D+  NG++ C                    +PF+L   + N + +    
Sbjct: 369 TVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDR 428

Query: 455 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514
            LD E+  EY + ++A D G PPLN +    IK+ DENDN P FT+    + + ENN PG
Sbjct: 429 PLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPG 488

Query: 515 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSL------DRRTGMLTVVKKLDREKEDKY 568
             L  V A D D G N  ++Y + P    + S+      +   G +  ++  + E+   +
Sbjct: 489 EYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAF 548

Query: 569 LFTILAKDNGVPP-LTSNVTVFVSIIDQNDNSPVFT-----HNEYKFYVPENLPRHGTVG 622
            F +LAKD+G P  L SN TV V+++D NDN+PV       ++  +  VP N      V 
Sbjct: 549 EFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVS 608

Query: 623 LITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDG 680
            +   D D+G++  +T  I+D NDD  F ID  +G IR    F  +        VK  D 
Sbjct: 609 TVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDH 668

Query: 681 GRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP 719
           G+ + S+ AK+ I  V  +  + V  V    + +++ LP
Sbjct: 669 GKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLP 707



 Score =  270 bits (691), Expect = 5e-72
 Identities = 278/1042 (26%), Positives = 432/1042 (41%), Gaps = 159/1042 (15%)

Query: 168  APLFPATVINISIPENSAINS-----------KYTLPAAVDPDVGINGVQNYELIKSQNI 216
            AP      +N S+PE     +           +  LP A     G +   +Y ++++   
Sbjct: 13   APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72

Query: 217  FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 276
              LDV +   G     L  ++ +DRE    +  K ++    F       +++V + D ND
Sbjct: 73   HLLDV-DADSG----LLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDIND 127

Query: 277  NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 336
            N P F   +IE+ I ENA  GT      A D D GEN    +    L++     LF L+ 
Sbjct: 128  NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTY----LLTRDDHGLFGLDV 183

Query: 337  TTG-------LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSI 387
             +         + I++ LDRE+  +H L++ A DGG  P  A V +NV   D NDN P  
Sbjct: 184  KSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVF 243

Query: 388  DI-RYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS- 445
            +   Y+V        L EN PL T +  +  TD D   NG V       +P R+R +FS 
Sbjct: 244  EAPSYLVE-------LPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSI 296

Query: 446  --NQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFV 503
                 L+     LDYE      I + A D G  P+     + +K+ D NDNAP     FV
Sbjct: 297  DPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSI--GFV 354

Query: 504  TV---SIPENNSPGIQLMKVSATDADSGPNAEINY-------------LLGPDAPPEFSL 547
            +V   ++ E   PG  +  V  TD DSG N ++               L GP     F L
Sbjct: 355  SVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL 414

Query: 548  DRR-TGMLTVV--KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 604
            +       TVV  + LDRE +D+Y  TI+A+D G PPL S  +  + I+D+NDN P FT 
Sbjct: 415  EENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTK 474

Query: 605  NEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD-------FTIDSQTGVI 657
              Y   V EN      +G +   DPD G N  V+ SIL  +          +++   G I
Sbjct: 475  GLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAI 534

Query: 658  RPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFIVPPY-NYSYE 715
                SF+ E+ +++ F V A+D G  +   S+A V + V+DVNDN PV ++P   N + E
Sbjct: 535  YALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAE 594

Query: 716  LVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKC--D 772
            L +P +   G +V  V A+D+D G +  + Y IV GN   LF ID  +G I  +     D
Sbjct: 595  LQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWED 654

Query: 773  VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEI 832
            VT   +  ++VK  D G+P                    + + +L+ +S+   +      
Sbjct: 655  VTP--VVELVVKVTDHGKP------------------TLSAVAKLIIRSVSGSLPEGVPR 694

Query: 833  ADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPE 892
             +      D    L+  ++    +++   IT  V+C++  + +    N + +E++ P   
Sbjct: 695  VNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKR-ENKEIRTYNCRIAEYSHPQ-- 751

Query: 893  NRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYN 952
                 +   K KKKK +  +++L    +EE  A                      M   N
Sbjct: 752  -----LGGGKGKKKKINKNDIMLVQSEVEERNA----------------------MNVMN 784

Query: 953  WVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQEL-PLDNTFVACDSIS 1011
             V++P+               A+    F  Q   PL+     +  L P  N        +
Sbjct: 785  VVSSPSL--------------ATSPMYFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHA 830

Query: 1012 NCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAG 1071
             C +S +     +    P T   + +     P++     ++    Q   S     D +  
Sbjct: 831  GCHTSFTG-QGTNASETPATRMSI-IQTDNFPAEPN---YMGSRQQFVQSSSTFKDPERA 885

Query: 1072 SLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEIT---VQPTVEEA 1128
            SL  + HG           D     +  + +  S  + +    LK + T    QP  +E 
Sbjct: 886  SLRDSGHG-----------DSDQADSDQDTNKGSCCDMSVREALKMKTTSTKSQPLEQEP 934

Query: 1129 SD--NCTQECLIYGHSDACWMP 1148
             +  NCT EC + GHSD CWMP
Sbjct: 935  EECVNCTDECRVLGHSDRCWMP 956


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  352 bits (904), Expect = 1e-96
 Identities = 219/676 (32%), Positives = 352/676 (52%), Gaps = 50/676 (7%)

Query: 45  LLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDV 104
           +L+  ++ +G  +  Y++ EE+ +   +G++ +DL L   P +     ++   +   G  
Sbjct: 18  ILLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR---IIPRGRT 72

Query: 105 PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDI 164
            L  +   +G + T G RIDRE+LC G  +      ++ + IL ++  ++  +   + DI
Sbjct: 73  QLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGVEVEVRDI 126

Query: 165 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIET 224
           NDNAP F  + + I I EN+A   ++ LP A DPD+G N +Q+YEL  + + F L V   
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-FSLIVQNG 185

Query: 225 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 284
            +G K P+L++++ LDREEK  + + +   DGG P R+ TA ++V V D NDN P F + 
Sbjct: 186 ADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQP 245

Query: 285 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 344
           E   S+PEN  +GT +  ++ATD D G NA++ +SF   V + A ++F L+  +G I+  
Sbjct: 246 EYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTI 304

Query: 345 EPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSE 404
             LD EE+  +++ V A D     ARA VL+ V DVNDN P + +  + + V       E
Sbjct: 305 GELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV------PE 358

Query: 405 NIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEY 464
           N P  T IAL+ V D+D++ NG+V CF    +PF+L   + N + L     LD E    Y
Sbjct: 359 NSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSY 418

Query: 465 AIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATD 524
            I + A D G PPL+    + + V D NDN PVF Q+  +  IPENN  G+ L+ V+A D
Sbjct: 419 NITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHD 478

Query: 525 ADSGPNAEINYLL------GPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNG 578
            D   NA+I Y L      G       S++  TG+L  +   D E+       ++A+DNG
Sbjct: 479 PDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNG 538

Query: 579 VPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL--------------- 623
            PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+               
Sbjct: 539 HPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPGYLVTK 590

Query: 624 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
           +   D D G N+ ++  +L  ++   F++   TG +R   +         +  V  +D G
Sbjct: 591 VVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHG 650

Query: 682 RVSRSSSAKVTINVVD 697
           +   S++  +T+ V D
Sbjct: 651 QPPLSATVTLTVAVAD 666



 Score =  247 bits (631), Expect = 5e-65
 Identities = 196/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)

Query: 233 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 291
           L+    +DREE     +K ++  D     +     ++V V D NDN P F+E+E+E+ I 
Sbjct: 84  LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143

Query: 292 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 347
           ENA         HA D DIG+N+   +  S    N    L   N   G     + +K  L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200

Query: 348 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 405
           DREE   H L++ ASDGG  +    A + V V D NDN P+        P     V  EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254

Query: 406 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTK 462
           + L T++ ++  TD D   N  V  ++   +  +   VF    N   +     LD+E + 
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313

Query: 463 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSA 522
            Y +++ A D      +  A + I V D NDNAP    + +  S+PEN+  G  +  ++ 
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371

Query: 523 TDADSGPNAEINYLLGPDAPPEFSLDRRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 579
            D DS  N ++   +  + P  F L++  G    L     LDRE+   Y  T+ A D G 
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429

Query: 580 PPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 639
           PPL++   + +++ D NDN PVF    Y  Y+PEN PR  ++  +T  DPD  +N+ +T 
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489

Query: 640 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 692
           S+ +        +   +I+S TGV+    SFD E+       V A D G    SS+  ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549

Query: 693 INVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 748
           + V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609

Query: 749 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 808
             +   LF++   TG +         D     ++V   D GQP  L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668

Query: 809 TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 867
               ++ +L   S+E+P   N+E +D++     Y+ + VAAV+      V++ +   +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717


>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  352 bits (904), Expect = 1e-96
 Identities = 219/676 (32%), Positives = 352/676 (52%), Gaps = 50/676 (7%)

Query: 45  LLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDV 104
           +L+  ++ +G  +  Y++ EE+ +   +G++ +DL L   P +     ++   +   G  
Sbjct: 18  ILLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR---IIPRGRT 72

Query: 105 PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDI 164
            L  +   +G + T G RIDRE+LC G  +      ++ + IL ++  ++  +   + DI
Sbjct: 73  QLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGVEVEVRDI 126

Query: 165 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIET 224
           NDNAP F  + + I I EN+A   ++ LP A DPD+G N +Q+YEL  + + F L V   
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-FSLIVQNG 185

Query: 225 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 284
            +G K P+L++++ LDREEK  + + +   DGG P R+ TA ++V V D NDN P F + 
Sbjct: 186 ADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQP 245

Query: 285 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 344
           E   S+PEN  +GT +  ++ATD D G NA++ +SF   V + A ++F L+  +G I+  
Sbjct: 246 EYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTI 304

Query: 345 EPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSE 404
             LD EE+  +++ V A D     ARA VL+ V DVNDN P + +  + + V       E
Sbjct: 305 GELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV------PE 358

Query: 405 NIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEY 464
           N P  T IAL+ V D+D++ NG+V CF    +PF+L   + N + L     LD E    Y
Sbjct: 359 NSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSY 418

Query: 465 AIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATD 524
            I + A D G PPL+    + + V D NDN PVF Q+  +  IPENN  G+ L+ V+A D
Sbjct: 419 NITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHD 478

Query: 525 ADSGPNAEINYLL------GPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNG 578
            D   NA+I Y L      G       S++  TG+L  +   D E+       ++A+DNG
Sbjct: 479 PDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNG 538

Query: 579 VPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL--------------- 623
            PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+               
Sbjct: 539 HPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPGYLVTK 590

Query: 624 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
           +   D D G N+ ++  +L  ++   F++   TG +R   +         +  V  +D G
Sbjct: 591 VVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHG 650

Query: 682 RVSRSSSAKVTINVVD 697
           +   S++  +T+ V D
Sbjct: 651 QPPLSATVTLTVAVAD 666



 Score =  247 bits (631), Expect = 5e-65
 Identities = 196/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)

Query: 233 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 291
           L+    +DREE     +K ++  D     +     ++V V D NDN P F+E+E+E+ I 
Sbjct: 84  LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143

Query: 292 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 347
           ENA         HA D DIG+N+   +  S    N    L   N   G     + +K  L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200

Query: 348 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 405
           DREE   H L++ ASDGG  +    A + V V D NDN P+        P     V  EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254

Query: 406 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTK 462
           + L T++ ++  TD D   N  V  ++   +  +   VF    N   +     LD+E + 
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313

Query: 463 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSA 522
            Y +++ A D      +  A + I V D NDNAP    + +  S+PEN+  G  +  ++ 
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371

Query: 523 TDADSGPNAEINYLLGPDAPPEFSLDRRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 579
            D DS  N ++   +  + P  F L++  G    L     LDRE+   Y  T+ A D G 
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429

Query: 580 PPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 639
           PPL++   + +++ D NDN PVF    Y  Y+PEN PR  ++  +T  DPD  +N+ +T 
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489

Query: 640 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 692
           S+ +        +   +I+S TGV+    SFD E+       V A D G    SS+  ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549

Query: 693 INVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 748
           + V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609

Query: 749 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 808
             +   LF++   TG +         D     ++V   D GQP  L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668

Query: 809 TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 867
               ++ +L   S+E+P   N+E +D++     Y+ + VAAV+      V++ +   +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717


>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 810

 Score =  349 bits (895), Expect = 1e-95
 Identities = 231/664 (34%), Positives = 346/664 (52%), Gaps = 50/664 (7%)

Query: 55  AQEKNYTIREEIPENVLIGNLLKDLNLSL--IPNKSLTTTMQFKLVYKTGDVPLIRIEED 112
           +Q+  YTI EE+     +G L KDL LS+  +P + L  + +              +  +
Sbjct: 28  SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77

Query: 113 TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 171
           +G++   G RIDREK+C    R   C  E E VA  P  +F +V +   I+DINDNAP F
Sbjct: 78  SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130

Query: 172 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 231
            A  I++ I E++    K++L +A D DV  N ++ Y +  +Q  F L   E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189

Query: 232 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 291
            L+++K LDRE + ++ + +   DGG P  S T  + + VTD NDN PVF +    VS+ 
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249

Query: 292 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 351
           EN P GTSV ++ ATD D G NA+I ++F N  S I+  LF+LN  TG IT    LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307

Query: 352 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 411
           T  + L V A DGG+  A   V + + D NDN P +      N +       E+  L T 
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361

Query: 412 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAA 471
           IALI V DKD+  NG VTC+T  E+PF+L     N + L  A  L+ E T +Y + ++A 
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421

Query: 472 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNA 531
           D GKP L+    + + + D NDNAPVF Q+   V + ENN PG  + +VSA+D D GPN 
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481

Query: 532 EINY-LLGPDAPPE-----FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 585
            ++Y +L  D  P       S+  ++G++   +  D E+   +  T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541

Query: 586 VTVFVSIIDQNDNSPVFTHNEYKFYVPEN------LPRHGTVGL----ITVTDPDYGDNS 635
           V++ V + D NDN+P      Y    P+       +PR    G     +   D D G N+
Sbjct: 542 VSLRVLVGDLNDNAPRVL---YPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNA 598

Query: 636 AVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 693
            ++  +L  ++   F++  +TG +R   +            V   DGG+   S++A + +
Sbjct: 599 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHL 658

Query: 694 NVVD 697
              D
Sbjct: 659 IFAD 662



 Score =  234 bits (596), Expect = 5e-61
 Identities = 188/709 (26%), Positives = 328/709 (46%), Gaps = 53/709 (7%)

Query: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 234
           I  +IPE  A  S+     A D  + +  +   +L + +++ F + +     GD    L+
Sbjct: 31  IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82

Query: 235 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 293
           V   +DRE+     ++  +E     +       + V + D NDN P F    I++ I E+
Sbjct: 83  VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142

Query: 294 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 352
           A  G   +   A DAD+ G + K++    N   +++ +     +   ++ +++PLDRE  
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202

Query: 353 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 410
            +H+L++ A DGG  P      + + VTD NDN P      + +     V L EN+P  T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256

Query: 411 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLL 469
            +  +  TD+D   N  +T  F +  I   L  +  N   +     LD+E T  Y + + 
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316

Query: 470 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529
           A D G    + +    I++ DENDNAP  T    +  IPE++  G  +  +   D DSG 
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374

Query: 530 NAEINYLLGPDAPPEF-SLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTV 588
           N  +      + P +  S  +    L +   L+RE+   Y  TI+A D G P L+S  ++
Sbjct: 375 NGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSI 434

Query: 589 FVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD- 647
            + I D NDN+PVF    Y  +V EN P   ++  ++ +DPD G N  V+ SIL  + + 
Sbjct: 435 TLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEP 494

Query: 648 ------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDN 701
                  ++  Q+GV+    +FD E+  ++   ++A D G  + S++  + + V D+NDN
Sbjct: 495 RELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDN 554

Query: 702 KPVFIVPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFA 757
            P  + P         +++V  +  PG +V +V+AVD D+G NA + Y ++  +   LF+
Sbjct: 555 APRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFS 614

Query: 758 IDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINEL 817
           +   TG +         D    R+LV   D GQP    +  +  +F +            
Sbjct: 615 LGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFAD------------ 662

Query: 818 VRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 866
              S++  +   ++  + S P ++    LV A+A    ++ V+F+ AV+
Sbjct: 663 ---SLQEVLPDLSDRPEPSDPQTELQFYLVVALA----LISVLFLLAVI 704


>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 927

 Score =  349 bits (895), Expect = 1e-95
 Identities = 231/664 (34%), Positives = 346/664 (52%), Gaps = 50/664 (7%)

Query: 55  AQEKNYTIREEIPENVLIGNLLKDLNLSL--IPNKSLTTTMQFKLVYKTGDVPLIRIEED 112
           +Q+  YTI EE+     +G L KDL LS+  +P + L  + +              +  +
Sbjct: 28  SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77

Query: 113 TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 171
           +G++   G RIDREK+C    R   C  E E VA  P  +F +V +   I+DINDNAP F
Sbjct: 78  SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130

Query: 172 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 231
            A  I++ I E++    K++L +A D DV  N ++ Y +  +Q  F L   E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189

Query: 232 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 291
            L+++K LDRE + ++ + +   DGG P  S T  + + VTD NDN PVF +    VS+ 
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249

Query: 292 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 351
           EN P GTSV ++ ATD D G NA+I ++F N  S I+  LF+LN  TG IT    LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307

Query: 352 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 411
           T  + L V A DGG+  A   V + + D NDN P +      N +       E+  L T 
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361

Query: 412 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAA 471
           IALI V DKD+  NG VTC+T  E+PF+L     N + L  A  L+ E T +Y + ++A 
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421

Query: 472 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNA 531
           D GKP L+    + + + D NDNAPVF Q+   V + ENN PG  + +VSA+D D GPN 
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481

Query: 532 EINY-LLGPDAPPE-----FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 585
            ++Y +L  D  P       S+  ++G++   +  D E+   +  T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541

Query: 586 VTVFVSIIDQNDNSPVFTHNEYKFYVPEN------LPRHGTVGL----ITVTDPDYGDNS 635
           V++ V + D NDN+P      Y    P+       +PR    G     +   D D G N+
Sbjct: 542 VSLRVLVGDLNDNAPRVL---YPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNA 598

Query: 636 AVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 693
            ++  +L  ++   F++  +TG +R   +            V   DGG+   S++A + +
Sbjct: 599 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHL 658

Query: 694 NVVD 697
              D
Sbjct: 659 IFAD 662



 Score =  234 bits (596), Expect = 5e-61
 Identities = 188/709 (26%), Positives = 328/709 (46%), Gaps = 53/709 (7%)

Query: 176 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 234
           I  +IPE  A  S+     A D  + +  +   +L + +++ F + +     GD    L+
Sbjct: 31  IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82

Query: 235 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 293
           V   +DRE+     ++  +E     +       + V + D NDN P F    I++ I E+
Sbjct: 83  VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142

Query: 294 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 352
           A  G   +   A DAD+ G + K++    N   +++ +     +   ++ +++PLDRE  
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202

Query: 353 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 410
            +H+L++ A DGG  P      + + VTD NDN P      + +     V L EN+P  T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256

Query: 411 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLL 469
            +  +  TD+D   N  +T  F +  I   L  +  N   +     LD+E T  Y + + 
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316

Query: 470 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 529
           A D G    + +    I++ DENDNAP  T    +  IPE++  G  +  +   D DSG 
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374

Query: 530 NAEINYLLGPDAPPEF-SLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTV 588
           N  +      + P +  S  +    L +   L+RE+   Y  TI+A D G P L+S  ++
Sbjct: 375 NGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSI 434

Query: 589 FVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD- 647
            + I D NDN+PVF    Y  +V EN P   ++  ++ +DPD G N  V+ SIL  + + 
Sbjct: 435 TLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEP 494

Query: 648 ------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDN 701
                  ++  Q+GV+    +FD E+  ++   ++A D G  + S++  + + V D+NDN
Sbjct: 495 RELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDN 554

Query: 702 KPVFIVPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFA 757
            P  + P         +++V  +  PG +V +V+AVD D+G NA + Y ++  +   LF+
Sbjct: 555 APRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFS 614

Query: 758 IDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINEL 817
           +   TG +         D    R+LV   D GQP    +  +  +F +            
Sbjct: 615 LGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFAD------------ 662

Query: 818 VRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 866
              S++  +   ++  + S P ++    LV A+A    ++ V+F+ AV+
Sbjct: 663 ---SLQEVLPDLSDRPEPSDPQTELQFYLVVALA----LISVLFLLAVI 704


>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
          Length = 1040

 Score =  348 bits (892), Expect = 3e-95
 Identities = 226/678 (33%), Positives = 352/678 (51%), Gaps = 57/678 (8%)

Query: 59  NYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFT 118
           +YT++EE      +GN+ +DL L +    +  +   F+ V      P + +  +TG ++ 
Sbjct: 21  HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75

Query: 119 TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 178
              +IDRE++C   P    C   +EV +  +    L ++   + DINDN P FP   + +
Sbjct: 76  N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129

Query: 179 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 238
            I E++   +++ L +A DPDVG N +++YE I   + F LDV    +G++  +L+++K 
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188

Query: 239 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 279
           LDRE++  +   +   DGG                     QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248

Query: 280 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 339
            F +    VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S  AR LF L+  TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308

Query: 340 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 397
            + +   LD EE+P +++ V A D G   +PA   VLV V D NDN P I    +   V 
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367

Query: 398 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLD 457
                SE     T +AL +VTD+D++ NG+V C    ++PFRL+  F N + +   A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422

Query: 458 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 517
            E+   Y + ++A D G+P L+ S  + ++V D NDNAP F+Q    V + ENN PG  +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482

Query: 518 MKVSATDADSGPNAEINY------LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFT 571
             VSATD D G NA++ Y      + G       S++   G L  ++  D E+   + F 
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542

Query: 572 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYKFYVPENLPRHGTVGL---- 623
           + A+D G P  L  N TV + I+DQNDN+P               E LPR    G     
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602

Query: 624 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 679
           +   D D G+N+ +T SI+  +E + F +D +TG +R    +   R+ Q  Y   ++  D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662

Query: 680 GGRVSRSSSAKVTINVVD 697
            G+   SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680



 Score =  233 bits (593), Expect = 1e-60
 Identities = 178/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)

Query: 267 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 326
           +++ V D NDN P F E ++ V I E+A  GT      A D D+G N+   +  +     
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162

Query: 327 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 365
                F L+  T         + +++PLDRE+   H+ ++ A DGG              
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221

Query: 366 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 418
             L P +     A++ + V D NDNVP+ D      PV  TV L EN P  T +  +  T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275

Query: 419 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTKEYAIKLLAADAGK 475
           D D   NG V       I  R R +F        LE +  LDYE +  Y + + A D G 
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335

Query: 476 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY 535
             +     + ++V D NDNAP  + S V  ++ E  +PG  +   S TD DS  N ++  
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395

Query: 536 LLGPDAPPEFSLDRRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 594
            L  D P       +     V +  LDRE  D Y  T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455

Query: 595 QNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 647
            NDN+P F+   Y  YV EN      +  ++ TD D G N+ +  SIL+           
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515

Query: 648 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 706
            +I+S+ G +    SFD E+ + ++F V+A D G     + +A V I +VD NDN P  +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575

Query: 707 VPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 762
            P    +     E++  S  PG ++ +V AVD D G NA + YSIV GN  +LF +D  T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635

Query: 763 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 808
           G +    +          + ++++  D GQP    +  +V   V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683



 Score =  190 bits (482), Expect = 9e-48
 Identities = 178/583 (30%), Positives = 256/583 (43%), Gaps = 78/583 (13%)

Query: 284 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 342
           +++  ++ E    GT V  +     D+G +  K+       V N       LN  TG++ 
Sbjct: 18  SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74

Query: 343 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 395
           + E +DRE+    +P+   H  + L +   L      V + V D+NDN PS        P
Sbjct: 75  VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123

Query: 396 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 445
             D TV +SE+    T+  L +  D D   N       D+EI       FS         
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177

Query: 446 NQF---LLENAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAM 483
           N+F   +LE    LD E    +   L A D                AG PP  Q   +A+
Sbjct: 178 NRFAELVLEKP--LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTAL 235

Query: 484 LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYL----LGP 539
           L I+V D NDN P F Q   TVS+PEN+ PG  +++++ATD D G N E+ Y     + P
Sbjct: 236 LTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISP 295

Query: 540 DAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNS 599
            A   F L  RTG L V  +LD E+   Y   + AKD G   + ++  V V ++D NDN+
Sbjct: 296 RARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNA 355

Query: 600 PVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---V 656
           P  + +  K  V E       V L +VTD D  +N  V   +L +   F + S       
Sbjct: 356 PEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYT 414

Query: 657 IRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYEL 716
           I      DRE  +SYT  V A D G  + S+S  + + V DVNDN P F  P Y+     
Sbjct: 415 IVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDV---Y 471

Query: 717 VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKC 771
           V  +  PG  ++ V A D D G NA++ YSI+     G +     +I+ E G +  +   
Sbjct: 472 VTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSF 531

Query: 772 DVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
           D   L      V+A D G P +L     VN+ + +   NA  I
Sbjct: 532 DYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAI 574



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

Query: 1131 NCTQECLIYGHSDACWMPASLDHSSSSQAQASALCHSPPL-SQASTQHHSPPVTQ 1184
            NCT+EC   GHSD CWMP+ +       A   +  H P + S   T+    P  Q
Sbjct: 939  NCTEECKALGHSDRCWMPSFVPSDGRQAADYRSNLHVPGMDSVPDTEVFETPEAQ 993


>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
          Length = 896

 Score =  348 bits (892), Expect = 3e-95
 Identities = 226/678 (33%), Positives = 352/678 (51%), Gaps = 57/678 (8%)

Query: 59  NYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFT 118
           +YT++EE      +GN+ +DL L +    +  +   F+ V      P + +  +TG ++ 
Sbjct: 21  HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75

Query: 119 TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 178
              +IDRE++C   P    C   +EV +  +    L ++   + DINDN P FP   + +
Sbjct: 76  N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129

Query: 179 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 238
            I E++   +++ L +A DPDVG N +++YE I   + F LDV    +G++  +L+++K 
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188

Query: 239 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 279
           LDRE++  +   +   DGG                     QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248

Query: 280 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 339
            F +    VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S  AR LF L+  TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308

Query: 340 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 397
            + +   LD EE+P +++ V A D G   +PA   VLV V D NDN P I    +   V 
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367

Query: 398 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLD 457
                SE     T +AL +VTD+D++ NG+V C    ++PFRL+  F N + +   A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422

Query: 458 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 517
            E+   Y + ++A D G+P L+ S  + ++V D NDNAP F+Q    V + ENN PG  +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482

Query: 518 MKVSATDADSGPNAEINY------LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFT 571
             VSATD D G NA++ Y      + G       S++   G L  ++  D E+   + F 
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542

Query: 572 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYKFYVPENLPRHGTVGL---- 623
           + A+D G P  L  N TV + I+DQNDN+P               E LPR    G     
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602

Query: 624 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 679
           +   D D G+N+ +T SI+  +E + F +D +TG +R    +   R+ Q  Y   ++  D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662

Query: 680 GGRVSRSSSAKVTINVVD 697
            G+   SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680



 Score =  233 bits (593), Expect = 1e-60
 Identities = 178/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)

Query: 267 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 326
           +++ V D NDN P F E ++ V I E+A  GT      A D D+G N+   +  +     
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162

Query: 327 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 365
                F L+  T         + +++PLDRE+   H+ ++ A DGG              
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221

Query: 366 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 418
             L P +     A++ + V D NDNVP+ D      PV  TV L EN P  T +  +  T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275

Query: 419 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTKEYAIKLLAADAGK 475
           D D   NG V       I  R R +F        LE +  LDYE +  Y + + A D G 
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335

Query: 476 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY 535
             +     + ++V D NDNAP  + S V  ++ E  +PG  +   S TD DS  N ++  
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395

Query: 536 LLGPDAPPEFSLDRRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 594
            L  D P       +     V +  LDRE  D Y  T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455

Query: 595 QNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 647
            NDN+P F+   Y  YV EN      +  ++ TD D G N+ +  SIL+           
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515

Query: 648 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 706
            +I+S+ G +    SFD E+ + ++F V+A D G     + +A V I +VD NDN P  +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575

Query: 707 VPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 762
            P    +     E++  S  PG ++ +V AVD D G NA + YSIV GN  +LF +D  T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635

Query: 763 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 808
           G +    +          + ++++  D GQP    +  +V   V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683



 Score =  190 bits (482), Expect = 9e-48
 Identities = 178/583 (30%), Positives = 256/583 (43%), Gaps = 78/583 (13%)

Query: 284 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 342
           +++  ++ E    GT V  +     D+G +  K+       V N       LN  TG++ 
Sbjct: 18  SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74

Query: 343 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 395
           + E +DRE+    +P+   H  + L +   L      V + V D+NDN PS        P
Sbjct: 75  VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123

Query: 396 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 445
             D TV +SE+    T+  L +  D D   N       D+EI       FS         
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177

Query: 446 NQF---LLENAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAM 483
           N+F   +LE    LD E    +   L A D                AG PP  Q   +A+
Sbjct: 178 NRFAELVLEKP--LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTAL 235

Query: 484 LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYL----LGP 539
           L I+V D NDN P F Q   TVS+PEN+ PG  +++++ATD D G N E+ Y     + P
Sbjct: 236 LTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISP 295

Query: 540 DAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNS 599
            A   F L  RTG L V  +LD E+   Y   + AKD G   + ++  V V ++D NDN+
Sbjct: 296 RARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNA 355

Query: 600 PVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---V 656
           P  + +  K  V E       V L +VTD D  +N  V   +L +   F + S       
Sbjct: 356 PEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYT 414

Query: 657 IRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYEL 716
           I      DRE  +SYT  V A D G  + S+S  + + V DVNDN P F  P Y+     
Sbjct: 415 IVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDV---Y 471

Query: 717 VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKC 771
           V  +  PG  ++ V A D D G NA++ YSI+     G +     +I+ E G +  +   
Sbjct: 472 VTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSF 531

Query: 772 DVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
           D   L      V+A D G P +L     VN+ + +   NA  I
Sbjct: 532 DYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAI 574


>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  346 bits (888), Expect = 8e-95
 Identities = 231/691 (33%), Positives = 352/691 (50%), Gaps = 62/691 (8%)

Query: 60  YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
           Y++ EE  +   +G++ KDL L   P +     ++   +   G   L  + + +G + T 
Sbjct: 33  YSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR---IISRGRTQLFALNQRSGSLVTA 87

Query: 120 GARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINIS 179
           G RIDRE++CA   R   C   V   IL ++   L  I   I DINDN P F    IN+ 
Sbjct: 88  G-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVK 141

Query: 180 IPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKEL 239
           I EN+A   ++ L  A DPDVG N +Q+Y+L  +++ F L V    +  K P+L++++ L
Sbjct: 142 IMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-FSLAVQSGDDETKYPELVLERVL 200

Query: 240 DREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTS 299
           DREE+  + + +   DGG P RSSTA +QV+V D ND+ PVF   + +V++PEN PVGT 
Sbjct: 201 DREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTR 260

Query: 300 VTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLV 359
           +  +HA D D G N ++ +SF  +   + + +FHLN+ TG I+  E LD EET  +++ V
Sbjct: 261 LLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSLTGEISTLEGLDYEETAFYEMEV 319

Query: 360 LASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTD 419
            A DG     +A VL+ V DVNDN P + +  + + +       E+ PL T IAL  + D
Sbjct: 320 QAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI------PEDTPLGTVIALFYLQD 373

Query: 420 KDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLN 479
           +D+  NG VTC     +PF+L     N + L     LD E+   Y I L A D G PPL+
Sbjct: 374 RDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLS 433

Query: 480 QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGP 539
           +   +F++V D NDN P F  S  +V I ENN  G  +  V+A D DS  NA+I Y L  
Sbjct: 434 RETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAE 493

Query: 540 D----APPE--FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSII 593
           D    AP     S++  TG+L  ++  D E+  +    + A D+G PPL+SN+++ + ++
Sbjct: 494 DTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVL 553

Query: 594 DQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------------ITVTDPDYGDNSAVT 638
           DQNDN P   +          LP  G+ G+               +   D D G N+ ++
Sbjct: 554 DQNDNPPEILY--------PALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLS 605

Query: 639 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 696
             +L  ++   F +   TG +R   +         +  V  +D G+   S++  +T+ V 
Sbjct: 606 YLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVA 665

Query: 697 DVNDNKPVFIVP---------PYNYSYELVL 718
              D+ P  +           PYNY   L L
Sbjct: 666 ---DSIPEVLADLGSLEPSDGPYNYDLTLYL 693



 Score =  246 bits (628), Expect = 1e-64
 Identities = 184/567 (32%), Positives = 267/567 (47%), Gaps = 42/567 (7%)

Query: 267 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 326
           + V + D NDN P F   EI V I EN   G       A D D+G N+   +  S     
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173

Query: 327 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 377
              R F L   +G    K P       LDREE   H L++ ASDGG  P  + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232

Query: 378 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 437
            DVND+ P   +          V + EN+P+ T++  +   D D   NG VT ++  +I 
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285

Query: 438 FRLRPVFSNQFL---LENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 494
            +L  +F    L   +     LDYE T  Y +++ A D   P     A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343

Query: 495 APVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAP--PEFSLDRRTG 552
           AP  T + ++ SIPE+   G  +      D DSG N E+   +  + P   E S+D    
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403

Query: 553 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVP 612
           ++T  K LDRE    Y  T+ A D G PPL+    +F+ + D NDN P F H+ Y  Y+ 
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462

Query: 613 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 665
           EN PR  ++ L+T  D D  DN+ +T S+ ++       +   +I+S TGV+    SFD 
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522

Query: 666 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPST 721
           E+       V A D G    SS+  +++ V+D NDN P  + P      +   EL   S 
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582

Query: 722 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 781
            PG +V +V+AVD D+G NA + Y ++  +   LFA+   TG +         D     +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642

Query: 782 LVKANDLGQPDSLFSVVIVNLFVNESV 808
           +V   D GQP  L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668


>gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precursor
           [Homo sapiens]
          Length = 817

 Score =  346 bits (888), Expect = 8e-95
 Identities = 231/691 (33%), Positives = 352/691 (50%), Gaps = 62/691 (8%)

Query: 60  YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 119
           Y++ EE  +   +G++ KDL L   P +     ++   +   G   L  + + +G + T 
Sbjct: 33  YSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR---IISRGRTQLFALNQRSGSLVTA 87

Query: 120 GARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINIS 179
           G RIDRE++CA   R   C   V   IL ++   L  I   I DINDN P F    IN+ 
Sbjct: 88  G-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVK 141

Query: 180 IPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKEL 239
           I EN+A   ++ L  A DPDVG N +Q+Y+L  +++ F L V    +  K P+L++++ L
Sbjct: 142 IMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-FSLAVQSGDDETKYPELVLERVL 200

Query: 240 DREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTS 299
           DREE+  + + +   DGG P RSSTA +QV+V D ND+ PVF   + +V++PEN PVGT 
Sbjct: 201 DREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTR 260

Query: 300 VTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLV 359
           +  +HA D D G N ++ +SF  +   + + +FHLN+ TG I+  E LD EET  +++ V
Sbjct: 261 LLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSLTGEISTLEGLDYEETAFYEMEV 319

Query: 360 LASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTD 419
            A DG     +A VL+ V DVNDN P + +  + + +       E+ PL T IAL  + D
Sbjct: 320 QAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI------PEDTPLGTVIALFYLQD 373

Query: 420 KDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLN 479
           +D+  NG VTC     +PF+L     N + L     LD E+   Y I L A D G PPL+
Sbjct: 374 RDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLS 433

Query: 480 QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGP 539
           +   +F++V D NDN P F  S  +V I ENN  G  +  V+A D DS  NA+I Y L  
Sbjct: 434 RETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAE 493

Query: 540 D----APPE--FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSII 593
           D    AP     S++  TG+L  ++  D E+  +    + A D+G PPL+SN+++ + ++
Sbjct: 494 DTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVL 553

Query: 594 DQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------------ITVTDPDYGDNSAVT 638
           DQNDN P   +          LP  G+ G+               +   D D G N+ ++
Sbjct: 554 DQNDNPPEILY--------PALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLS 605

Query: 639 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 696
             +L  ++   F +   TG +R   +         +  V  +D G+   S++  +T+ V 
Sbjct: 606 YLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVA 665

Query: 697 DVNDNKPVFIVP---------PYNYSYELVL 718
              D+ P  +           PYNY   L L
Sbjct: 666 ---DSIPEVLADLGSLEPSDGPYNYDLTLYL 693



 Score =  246 bits (628), Expect = 1e-64
 Identities = 184/567 (32%), Positives = 267/567 (47%), Gaps = 42/567 (7%)

Query: 267 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 326
           + V + D NDN P F   EI V I EN   G       A D D+G N+   +  S     
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173

Query: 327 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 377
              R F L   +G    K P       LDREE   H L++ ASDGG  P  + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232

Query: 378 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 437
            DVND+ P   +          V + EN+P+ T++  +   D D   NG VT ++  +I 
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285

Query: 438 FRLRPVFSNQFL---LENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 494
            +L  +F    L   +     LDYE T  Y +++ A D   P     A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343

Query: 495 APVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAP--PEFSLDRRTG 552
           AP  T + ++ SIPE+   G  +      D DSG N E+   +  + P   E S+D    
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403

Query: 553 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVP 612
           ++T  K LDRE    Y  T+ A D G PPL+    +F+ + D NDN P F H+ Y  Y+ 
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462

Query: 613 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 665
           EN PR  ++ L+T  D D  DN+ +T S+ ++       +   +I+S TGV+    SFD 
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522

Query: 666 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPST 721
           E+       V A D G    SS+  +++ V+D NDN P  + P      +   EL   S 
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582

Query: 722 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 781
            PG +V +V+AVD D+G NA + Y ++  +   LFA+   TG +         D     +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642

Query: 782 LVKANDLGQPDSLFSVVIVNLFVNESV 808
           +V   D GQP  L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668


>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
           [Homo sapiens]
          Length = 837

 Score =  345 bits (885), Expect = 2e-94
 Identities = 214/681 (31%), Positives = 351/681 (51%), Gaps = 54/681 (7%)

Query: 44  VLLVCVVFHS----GAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 99
           +LL+C+   +     A++  Y++ EE  +   +GN+ KDL L   P +     ++   + 
Sbjct: 14  LLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLE--PRELAKRGVR---IV 68

Query: 100 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 159
             G   L  +   +G + T G RIDRE+LC  +     CF  +E  +L ++  ++  +  
Sbjct: 69  SRGKTQLFAVNPRSGSLITAG-RIDREELCETV---SSCFLNME--LLVEDTLKIYGVEV 122

Query: 160 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 219
            I DINDNAP F    + I + E++   +++ LP A DPDVG+N +Q+Y+L    N F L
Sbjct: 123 EIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQL-SPNNYFSL 181

Query: 220 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 279
            +    +G K P+L+++  LDRE++  +++ +   DGG P R     ++V V D ND+ P
Sbjct: 182 QLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIP 241

Query: 280 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 339
           +F ++   VS+PEN   GT V  ++ATD D G N ++ +SF N+ S  A  +F L++ TG
Sbjct: 242 MFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMESK-ASEIFQLDSQTG 300

Query: 340 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 399
            + ++  LD E+   +++ +   DGG +     +L+ V DVNDN P I I   +N +   
Sbjct: 301 EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSI--- 357

Query: 400 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 459
               EN P  T IAL+ V D+D+  NG+V+CF  + +PF+L   + N + L  +  LD E
Sbjct: 358 ---LENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRE 414

Query: 460 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK 519
             + Y I L A D G PPL+    +++ V D+NDN PVF  S  +  IPENN  G  +  
Sbjct: 415 LVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFS 474

Query: 520 VSATDADSGPNAEINYLLGPDA------PPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 573
           V+A D DS  NA + Y L  D           S++  TG+L  ++  D E+       ++
Sbjct: 475 VTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVI 534

Query: 574 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------- 623
           A+D+G PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+          
Sbjct: 535 ARDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 586

Query: 624 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 676
                +   D D G N+ ++  +L  ++   F +   TG +R   +         +  V 
Sbjct: 587 YLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 646

Query: 677 AEDGGRVSRSSSAKVTINVVD 697
            +D G+   S++  +T+ V D
Sbjct: 647 VQDHGQPPLSATVTLTVAVAD 667



 Score =  251 bits (642), Expect = 3e-66
 Identities = 211/725 (29%), Positives = 334/725 (46%), Gaps = 71/725 (9%)

Query: 171 FPATVINISIPENSAINSKYTLPAAVDPDVGIN-------GVQNYELIKSQNIFGLDVIE 223
           F A  I  S+PE +    K +    +  D+G+        GV+     K+Q +F ++   
Sbjct: 27  FRARQIRYSVPEET---EKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQ-LFAVN--- 79

Query: 224 TPEGDKMPQLIVQKELDREEKDTYV------MKVKVEDGGFPQRSSTAILQVSVTDTNDN 277
                +   LI    +DREE    V      M++ VED           ++V + D NDN
Sbjct: 80  ----PRSGSLITAGRIDREELCETVSSCFLNMELLVED-----TLKIYGVEVEIIDINDN 130

Query: 278 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVSNIARRLFHLNA 336
            P F+E E+E+ + E+A  G      +A D D+G N+   +  S N   ++  R     A
Sbjct: 131 APSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGA 190

Query: 337 TTGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVN 394
               + ++  LDRE+   H LL+ A DGG  +      + V V DVND++P         
Sbjct: 191 KNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVY-- 248

Query: 395 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF---SNQFLLE 451
                V + ENI   T++ ++  TD D   NG V  ++   +  +   +F   S    ++
Sbjct: 249 ----RVSVPENISSGTRVLMVNATDPDEGINGEVM-YSFRNMESKASEIFQLDSQTGEVQ 303

Query: 452 NAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 511
               LD+E  + Y +++   D G   L  +  + I V D NDNAP  T +    SI EN+
Sbjct: 304 VRGSLDFEKYRFYEMEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENS 361

Query: 512 SPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTG---MLTVVKKLDREKEDKY 568
            PG  +  ++  D DSG N +++  +    P  F L++  G    L   + LDRE    Y
Sbjct: 362 PPGTVIALLNVQDQDSGENGQVSCFIPNHLP--FKLEKTYGNYYKLITSRVLDRELVQSY 419

Query: 569 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTD 628
             T+ A D G PPL++   V++++ D NDN PVF H+ Y  Y+PEN PR  ++  +T  D
Sbjct: 420 NITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALD 479

Query: 629 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
           PD   N+ VT S+ D+       +   +I+S TGV+    SFD E+       V A D G
Sbjct: 480 PDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSG 539

Query: 682 RVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDT 737
               SS+  +++ V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+
Sbjct: 540 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDS 599

Query: 738 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 797
           G NA + Y ++  +   LFA+ + TG +         D     ++V   D GQP    +V
Sbjct: 600 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 659

Query: 798 VIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 857
            +       +V  A  I E++          N+E +D+S     Y+ + VAAV+    V 
Sbjct: 660 TL-------TVAVADSIPEVLADLGSLESLANSETSDLSL----YLVVAVAAVSCIFLVF 708

Query: 858 VVIFI 862
           V++ +
Sbjct: 709 VIVLL 713


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,241,714
Number of Sequences: 37866
Number of extensions: 2514214
Number of successful extensions: 17903
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 201
Number of HSP's successfully gapped in prelim test: 109
Number of HSP's that attempted gapping in prelim test: 7830
Number of HSP's gapped (non-prelim): 1481
length of query: 1340
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1226
effective length of database: 13,930,794
effective search space: 17079153444
effective search space used: 17079153444
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.