Guide to the Human Genome
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Search of human proteins with 14589918

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
         (1025 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ...  2032   0.0  
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s...  2006   0.0  
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]       2005   0.0  
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]       2005   0.0  
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]       1971   0.0  
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]       1971   0.0  
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]       1964   0.0  
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]       1184   0.0  
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]        1183   0.0  
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]        662   0.0  
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]        660   0.0  
gi|190194360 protocadherin 20 [Homo sapiens]                          628   e-180
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]        605   e-173
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]        605   e-173
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]        586   e-167
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur...   364   e-100
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur...   364   e-100
gi|14589929 protocadherin 18 precursor [Homo sapiens]                 358   1e-98
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs...   357   4e-98
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur...   357   4e-98
gi|94538350 protocadherin 17 precursor [Homo sapiens]                 355   9e-98
gi|157426847 protocadherin 19 isoform a [Homo sapiens]                352   1e-96
gi|157426845 protocadherin 19 isoform b [Homo sapiens]                352   1e-96
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs...   351   2e-96
gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precurs...   351   2e-96
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs...   349   9e-96
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs...   349   9e-96
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]       348   1e-95
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]       348   1e-95
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur...   346   7e-95

>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
            sapiens]
          Length = 1025

 Score = 2032 bits (5264), Expect = 0.0
 Identities = 1025/1025 (100%), Positives = 1025/1025 (100%)

Query: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
            MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60

Query: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
            MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120

Query: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
            RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180

Query: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
            SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240

Query: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
            DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300

Query: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
            HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360

Query: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
            VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420

Query: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
            AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480

Query: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
            PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540

Query: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
            LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600

Query: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
            DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660

Query: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
            INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720

Query: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
            RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780

Query: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
            LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840

Query: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
            HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900

Query: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
            NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960

Query: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTSTIE 1020
            HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTSTIE
Sbjct: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTSTIE 1020

Query: 1021 ICSEI 1025
            ICSEI
Sbjct: 1021 ICSEI 1025


>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
            sapiens]
          Length = 1021

 Score = 2006 bits (5197), Expect = 0.0
 Identities = 1012/1017 (99%), Positives = 1013/1017 (99%)

Query: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
            MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60

Query: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
            MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120

Query: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
            RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180

Query: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
            SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240

Query: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
            DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300

Query: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
            HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360

Query: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
            VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420

Query: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
            AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480

Query: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
            PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540

Query: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
            LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600

Query: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
            DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660

Query: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
            INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720

Query: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
            RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780

Query: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
            LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840

Query: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
            HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900

Query: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
            NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960

Query: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTS 1017
            HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP   + S
Sbjct: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPVGIQVS 1017


>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
          Length = 1337

 Score = 2005 bits (5195), Expect = 0.0
 Identities = 1011/1011 (100%), Positives = 1011/1011 (100%)

Query: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
            MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60

Query: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
            MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120

Query: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
            RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180

Query: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
            SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240

Query: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
            DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300

Query: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
            HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360

Query: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
            VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420

Query: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
            AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480

Query: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
            PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540

Query: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
            LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600

Query: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
            DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660

Query: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
            INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720

Query: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
            RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780

Query: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
            LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840

Query: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
            HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900

Query: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
            NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960

Query: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
            HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011


>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
          Length = 1347

 Score = 2005 bits (5195), Expect = 0.0
 Identities = 1011/1011 (100%), Positives = 1011/1011 (100%)

Query: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
            MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1    MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60

Query: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
            MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61   MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120

Query: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
            RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121  RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180

Query: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
            SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181  SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240

Query: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
            DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241  DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300

Query: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
            HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301  HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360

Query: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
            VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361  VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420

Query: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
            AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421  AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480

Query: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
            PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481  PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540

Query: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
            LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541  LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600

Query: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
            DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601  DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660

Query: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
            INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661  INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720

Query: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
            RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721  RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780

Query: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
            LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781  LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840

Query: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
            HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900

Query: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
            NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960

Query: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
            HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 961  HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011


>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
          Length = 1048

 Score = 1971 bits (5106), Expect = 0.0
 Identities = 997/1014 (98%), Positives = 1000/1014 (98%)

Query: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
            LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94

Query: 63   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
            FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 95   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154

Query: 123  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
            VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 155  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214

Query: 183  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
            NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 215  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274

Query: 243  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
            NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 275  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334

Query: 303  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
            NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 335  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394

Query: 363  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
            PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 395  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454

Query: 423  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
            YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 455  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514

Query: 483  IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
            IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 515  IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574

Query: 543  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
            KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 575  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634

Query: 603  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
            SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 635  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694

Query: 663  VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
            VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 695  VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754

Query: 723  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
            LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 755  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814

Query: 783  NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
            NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 815  NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874

Query: 843  KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
            KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 875  KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934

Query: 903  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
            VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 935  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994

Query: 963  IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT 1016
            IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT
Sbjct: 995  IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT 1048


>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
          Length = 1037

 Score = 1971 bits (5106), Expect = 0.0
 Identities = 997/1014 (98%), Positives = 1000/1014 (98%)

Query: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
            LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 24   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83

Query: 63   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
            FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 84   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 143

Query: 123  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
            VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 144  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 203

Query: 183  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
            NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 204  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 263

Query: 243  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
            NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 264  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 323

Query: 303  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
            NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 324  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 383

Query: 363  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
            PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 384  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 443

Query: 423  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
            YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 444  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 503

Query: 483  IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
            IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 504  IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 563

Query: 543  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
            KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 564  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 623

Query: 603  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
            SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 624  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 683

Query: 663  VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
            VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 684  VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 743

Query: 723  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
            LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 744  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803

Query: 783  NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
            NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 804  NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 863

Query: 843  KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
            KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 864  KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 923

Query: 903  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
            VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 924  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 983

Query: 963  IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT 1016
            IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT
Sbjct: 984  IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT 1037


>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
          Length = 1340

 Score = 1964 bits (5087), Expect = 0.0
 Identities = 993/1015 (97%), Positives = 998/1015 (98%)

Query: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
            LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 35   LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94

Query: 63   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
            FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 95   FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154

Query: 123  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
            VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 155  VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214

Query: 183  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
            NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 215  NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274

Query: 243  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
            NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 275  NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334

Query: 303  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
            NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 335  NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394

Query: 363  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
            PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 395  PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454

Query: 423  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
            YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 455  YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514

Query: 483  IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
            IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 515  IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574

Query: 543  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
            KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 575  KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634

Query: 603  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
            SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 635  SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694

Query: 663  VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
            VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 695  VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754

Query: 723  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
            LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 755  LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814

Query: 783  NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
            NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 815  NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874

Query: 843  KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
            KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 875  KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934

Query: 903  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
            VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 935  VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994

Query: 963  IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTS 1017
            IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP+  R +
Sbjct: 995  IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPSQRRVT 1049


>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
          Length = 1237

 Score = 1184 bits (3062), Expect = 0.0
 Identities = 594/1023 (58%), Positives = 782/1023 (76%), Gaps = 16/1023 (1%)

Query: 8    YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
            Y+ A L+AC+   S  AQE  YTIREE+PENV IG++ KDLN+S I   + T+A + ++L
Sbjct: 7    YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66

Query: 66   VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 123
            V K GD PL+++   TGEIFTT  RIDREKLCAG     +  CF+E+EV ILP++ FRL+
Sbjct: 67   VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126

Query: 124  KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
            KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+  Q+
Sbjct: 127  KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186

Query: 184  IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
            +FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187  VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246

Query: 244  DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
            DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F   V+   +RLF LN
Sbjct: 247  DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306

Query: 304  ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
             TTGLIT++  LDREET  HK+ VLASDG   PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307  NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366

Query: 364  VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
            +N TV LSE  P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++ 
Sbjct: 367  INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426

Query: 424  LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
            LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q  + +S+ ENN  G+
Sbjct: 427  LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486

Query: 484  QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
             LT +SA D DSG NA I Y LGP+A   F LD +TG+LT  +  DRE++++++FT+ A+
Sbjct: 487  YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545

Query: 544  DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
            DNG PPL S   V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N 
Sbjct: 546  DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605

Query: 604  AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
            AVTLSIL++ND+F +D  +GVI+ N+SFDRE+Q SYTF VKA DGG+  RSS+AKVTINV
Sbjct: 606  AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665

Query: 664  VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
            +DVNDN PV I PPSN S++LV  S  PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666  MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725

Query: 724  FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
            F ID  TGNITL EK   TD+GLHR++V  +DLG P SL ++V+V L+VN++  NA+ I 
Sbjct: 726  FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785

Query: 784  ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
            +L+R++ E P+  N  I D S P    DY+ I++A +AG + V+VVIF+T +VRCR A  
Sbjct: 786  DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843

Query: 842  LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
             KAAQ++KQ +EW +PN EN+Q    KKKK+KK+ SPK+ LLNFVTIEE+K DD   +  
Sbjct: 844  FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900

Query: 902  RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
              T+ LP +LEEQ++G+++W    PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++  K
Sbjct: 901  NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960

Query: 960  HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTST 1018
            HH+IQELPLDNTFV  CD++SK SS+SSD +S S+C      F+    +HTR  +S + +
Sbjct: 961  HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQCNSHSKS 1019

Query: 1019 IEI 1021
              I
Sbjct: 1020 DNI 1022


>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
          Length = 1203

 Score = 1183 bits (3061), Expect = 0.0
 Identities = 593/1019 (58%), Positives = 780/1019 (76%), Gaps = 16/1019 (1%)

Query: 8    YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
            Y+ A L+AC+   S  AQE  YTIREE+PENV IG++ KDLN+S I   + T+A + ++L
Sbjct: 7    YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66

Query: 66   VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 123
            V K GD PL+++   TGEIFTT  RIDREKLCAG     +  CF+E+EV ILP++ FRL+
Sbjct: 67   VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126

Query: 124  KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
            KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+  Q+
Sbjct: 127  KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186

Query: 184  IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
            +FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187  VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246

Query: 244  DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
            DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F   V+   +RLF LN
Sbjct: 247  DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306

Query: 304  ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
             TTGLIT++  LDREET  HK+ VLASDG   PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307  NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366

Query: 364  VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
            +N TV LSE  P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++ 
Sbjct: 367  INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426

Query: 424  LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
            LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q  + +S+ ENN  G+
Sbjct: 427  LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486

Query: 484  QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
             LT +SA D DSG NA I Y LGP+A   F LD +TG+LT  +  DRE++++++FT+ A+
Sbjct: 487  YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545

Query: 544  DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
            DNG PPL S   V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N 
Sbjct: 546  DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605

Query: 604  AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
            AVTLSIL++ND+F +D  +GVI+ N+SFDRE+Q SYTF VKA DGG+  RSS+AKVTINV
Sbjct: 606  AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665

Query: 664  VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
            +DVNDN PV I PPSN S++LV  S  PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666  MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725

Query: 724  FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
            F ID  TGNITL EK   TD+GLHR++V  +DLG P SL ++V+V L+VN++  NA+ I 
Sbjct: 726  FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785

Query: 784  ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
            +L+R++ E P+  N  I D S P    DY+ I++A +AG + V+VVIF+T +VRCR A  
Sbjct: 786  DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843

Query: 842  LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
             KAAQ++KQ +EW +PN EN+Q    KKKK+KK+ SPK+ LLNFVTIEE+K DD   +  
Sbjct: 844  FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900

Query: 902  RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
              T+ LP +LEEQ++G+++W    PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++  K
Sbjct: 901  NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960

Query: 960  HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTS 1017
            HH+IQELPLDNTFV  CD++SK SS+SSD +S S+C      F+    +HTR +  R +
Sbjct: 961  HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQSQRRVT 1018


>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
          Length = 1237

 Score =  662 bits (1707), Expect = 0.0
 Identities = 408/1039 (39%), Positives = 580/1039 (55%), Gaps = 54/1039 (5%)

Query: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
            LL  + + A+LL        A    Y + EE P N LIG L  D     + +        
Sbjct: 37   LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88

Query: 63   FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
               +YK     P +R++  TG+IFTT   IDRE L  C      + C  E EV+I   + 
Sbjct: 89   ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145

Query: 117  DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
            +   RL++ +  ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146  NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205

Query: 177  ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
            EL    ++Q +FGL V E  E +K PQLIV   LDRE  D+Y + +KV+DGG P R+S+A
Sbjct: 206  ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264

Query: 234  ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
            +L+V+V DTNDN P F+    E  + EN+P+G SV Q+ A D+D G NA+I ++F     
Sbjct: 265  LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323

Query: 294  NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
             + RRL  L+  TGLIT++ P+DRE+    +  VLA D G  P  ARA V+V V D+NDN
Sbjct: 324  EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383

Query: 352  VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
             P+I+IR I  V   +    +SE++   T +AL+ V+D+D   N  VTC    ++PF+LR
Sbjct: 384  APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443

Query: 410  PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
                       ++ L+T   LDYE  K+Y I+++A D+G PPL+ +  L ++V D NDNA
Sbjct: 444  QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503

Query: 464  PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
            PVFTQS   V+ PENN PG  + +++A DADSG NA++ Y L P+   +  F++   TG 
Sbjct: 504  PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563

Query: 522  LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
            + V   LDRE+ + Y   ++A D G P L    TV V+++D NDN P F  + YNF V E
Sbjct: 564  IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623

Query: 582  NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
            N+P    VG++TV D D G+N+ V LS+  +N DF I + TG I  ++SFDRE+Q +YTF
Sbjct: 624  NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683

Query: 642  YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
             +KA DGG   RS+   VTINV+D NDN P +I  PSN S++L+ P T  G  V QV A 
Sbjct: 684  QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742

Query: 702  DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
            D D+G+NAE+ YSI GGN   LF I   +G ITL ++ +    GLHR++VK +D G+P  
Sbjct: 743  DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802

Query: 762  LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
             +   +V+L+VNE++ N TL+  L+  S + P+  +         +     IL   VAG 
Sbjct: 803  -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861

Query: 822  ITVVVVIFITAVVR-CRQAPHLKAAQK-NKQNSEWATPNPENRQMIMMKKKKKKKKHSPK 879
            + V ++I +  +VR CRQ       Q   K+  +   P P  +     K K KK K SPK
Sbjct: 862  VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920

Query: 880  NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
             +            +D D  G  +   L  +L     G    +  P  + P SPDL RHY
Sbjct: 921  PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969

Query: 940  KSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPV 998
            +S SP P+ Q+QP++P  + KH ++Q+LP  NTFV     +   S     YS        
Sbjct: 970  RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKY 1029

Query: 999  TTFEVPVSVHTRPTDSRTS 1017
             + ++P   H R T S TS
Sbjct: 1030 PSKQLP---HRRVTFSATS 1045


>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
          Length = 1060

 Score =  660 bits (1703), Expect = 0.0
 Identities = 401/1012 (39%), Positives = 570/1012 (56%), Gaps = 51/1012 (5%)

Query: 3    LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
            LL  + + A+LL        A    Y + EE P N LIG L  D     + +        
Sbjct: 37   LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88

Query: 63   FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
               +YK     P +R++  TG+IFTT   IDRE L  C      + C  E EV+I   + 
Sbjct: 89   ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145

Query: 117  DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
            +   RL++ +  ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146  NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205

Query: 177  ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
            EL    ++Q +FGL V E  E +K PQLIV   LDRE  D+Y + +KV+DGG P R+S+A
Sbjct: 206  ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264

Query: 234  ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
            +L+V+V DTNDN P F+    E  + EN+P+G SV Q+ A D+D G NA+I ++F     
Sbjct: 265  LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323

Query: 294  NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
             + RRL  L+  TGLIT++ P+DRE+    +  VLA D G  P  ARA V+V V D+NDN
Sbjct: 324  EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383

Query: 352  VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
             P+I+IR I  V   +    +SE++   T +AL+ V+D+D   N  VTC    ++PF+LR
Sbjct: 384  APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443

Query: 410  PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
                       ++ L+T   LDYE  K+Y I+++A D+G PPL+ +  L ++V D NDNA
Sbjct: 444  QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503

Query: 464  PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
            PVFTQS   V+ PENN PG  + +++A DADSG NA++ Y L P+   +  F++   TG 
Sbjct: 504  PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563

Query: 522  LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
            + V   LDRE+ + Y   ++A D G P L    TV V+++D NDN P F  + YNF V E
Sbjct: 564  IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623

Query: 582  NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
            N+P    VG++TV D D G+N+ V LS+  +N DF I + TG I  ++SFDRE+Q +YTF
Sbjct: 624  NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683

Query: 642  YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
             +KA DGG   RS+   VTINV+D NDN P +I  PSN S++L+ P T  G  V QV A 
Sbjct: 684  QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742

Query: 702  DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
            D D+G+NAE+ YSI GGN   LF I   +G ITL ++ +    GLHR++VK +D G+P  
Sbjct: 743  DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802

Query: 762  LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
             +   +V+L+VNE++ N TL+  L+  S + P+  +         +     IL   VAG 
Sbjct: 803  -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861

Query: 822  ITVVVVIFITAVVR-CRQAPHLKAAQK-NKQNSEWATPNPENRQMIMMKKKKKKKKHSPK 879
            + V ++I +  +VR CRQ       Q   K+  +   P P  +     K K KK K SPK
Sbjct: 862  VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920

Query: 880  NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
             +            +D D  G  +   L  +L     G    +  P  + P SPDL RHY
Sbjct: 921  PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969

Query: 940  KSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYS 990
            +S SP P+ Q+QP++P  + KH ++Q+LP  NTFV     +   S     YS
Sbjct: 970  RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021


>gi|190194360 protocadherin 20 [Homo sapiens]
          Length = 951

 Score =  628 bits (1620), Expect = e-180
 Identities = 347/820 (42%), Positives = 506/820 (61%), Gaps = 43/820 (5%)

Query: 8   YIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
           ++F    +C+  +S A E  Y++ E +P  VLIG L +DL L  +P  +     Q +L  
Sbjct: 50  FLFVGPFSCLGSYSRATELLYSLNEGLPAGVLIGSLAEDLRL--LPRSAGRPDPQSQLPE 107

Query: 68  KTG---DVPL-------------IRIEEDTGEIFTTGARIDREKLC-------------- 97
           +TG   + PL             + ++  +GE+ T+   IDRE LC              
Sbjct: 108 RTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVS 167

Query: 98  -AGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINS 156
            +  P D  C   ++V +LP E FR VK++  I DINDNAP FP + I++ +PEN+ +N+
Sbjct: 168 ISSSPSDS-CLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNT 226

Query: 157 KYTLP-AAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTY 215
           +  +   AVDPDVGINGVQ Y L+    +F LDV E   G++ P LIV   LDRE +D Y
Sbjct: 227 RLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQY 286

Query: 216 VMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD 275
           V  +  EDGG P    +A L + ++D NDN P+F +++I V++  NA VGT +  + A D
Sbjct: 287 VSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVD 346

Query: 276 ADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM 335
            D+G NA+I +S+S  V   ++ LFHL+  TG+I +   +      +HKL +LA+  G +
Sbjct: 347 KDLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCI 406

Query: 336 PARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGR 395
           PA    LV++  V    P I  RYI N ++  V L E  P+NT IA  T+ D +  +  +
Sbjct: 407 PAVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKY--K 464

Query: 396 VTCFTDHEIPFRLRPV--FSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLF 453
           V C+ D E PFRL P   ++N++LLET   +DYE  + Y + ++A ++     +   ++ 
Sbjct: 465 VNCYLDGEGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIK 522

Query: 454 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEF 513
           +++ D+NDNAP+F Q  + ++I ENNSP   LTK+ A DADS    +++Y LGPDAP  F
Sbjct: 523 VQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYF 582

Query: 514 SLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHN 573
           SLD  TG+LTV  +LDRE+++KY +T+ A D G PP  S  TV ++++D+NDNSP F + 
Sbjct: 583 SLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINK 642

Query: 574 EYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDR 633
           +++F+VPEN P +G +G+I+VTD D G N  V LS+++++D F ID+  G++R  +S DR
Sbjct: 643 DFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDR 702

Query: 634 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGT 693
           E+Q SYT +V+A DGG  + SS+AK+TI ++D+NDN P+ + P SN SY LVLPST PG+
Sbjct: 703 EQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGS 762

Query: 694 VVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLV 751
            V +V AVD DTGMNA + YSI+G  G   + F ID +TGNITL E    TD GLHR+LV
Sbjct: 763 PVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLV 822

Query: 752 KANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTE 791
           K +D G P+ L S V+VNLFVN++V+N + I  L+RK  E
Sbjct: 823 KVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPE 862


>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
          Length = 1072

 Score =  605 bits (1560), Expect = e-173
 Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)

Query: 28   YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
            Y + EE P +V IG++  DL +       +T + +     ++G    ++I+  TGE+ T+
Sbjct: 36   YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87

Query: 88   GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
              RIDREKL  C  I  +  CF + EV+++ P + +  L + + ++ DINDN P FP+ V
Sbjct: 88   ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147

Query: 144  INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
            + +++ EN  + + Y LP A D D G NG++ YEL+          +S+     D    P
Sbjct: 148  LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207

Query: 194  EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
             G                                 + +L V    D E++   ++K    
Sbjct: 208  GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267

Query: 219  ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
                      ++V DGG P RSS AIL+V +TD NDN P F+++  E  + EN+  GT +
Sbjct: 268  REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327

Query: 269  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
             QL A D D+G N +I + F     ++ RRL  L+ T+G +++   +DREE    +  V+
Sbjct: 328  LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386

Query: 329  ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
            A D G  P   +A V++N+ D NDNVPSI+IR I   P+ D V  ++E++ ++T IAL+ 
Sbjct: 387  ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446

Query: 385  VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
            V+D+D   NG VTC    ++PF+L+P    +       + L T+  LDYE+T+E+ + ++
Sbjct: 447  VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506

Query: 438  AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
            A D+G P L+ +  L +KV D NDN P+F QS V V  PENN PG ++  V A DADSG 
Sbjct: 507  AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566

Query: 498  NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
            NA+I Y L       F++D  +G + V   LDRE+ D+Y F + AKD G+P L  + TV 
Sbjct: 567  NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626

Query: 558  VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
            V + D+NDN P F  + + FYV ENL  +  VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627  VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686

Query: 618  IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
            I++ TG I   +SFDRE Q +YTF VKA DGG   RS++A V++ V+D NDN P  +  P
Sbjct: 687  IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745

Query: 678  SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
             N SY L+ PS+N  TVV  V+A D+D G+NA++ YSIVGGN   LF ID  +G ++L+ 
Sbjct: 746  KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805

Query: 738  KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
            K      GLHR++V+ ND GQP S  +  +V++FVNESV+NAT I+  + +S   P+T +
Sbjct: 806  KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864

Query: 798  TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
                     +   + I++  VAG +TV+++I I  + R CR           K + ++ T
Sbjct: 865  IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924

Query: 857  PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
            P   ++     K KK KK   P  L  + VT+E +K +    D     L      +  +M
Sbjct: 925  PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977

Query: 917  GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
            G+Y  V       P SPDLARHYKS+SP P  Q+ P++P    KH  +Q+LP  NTFV A
Sbjct: 978  GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033

Query: 975  CDSISKCSSSSSD 987
             D+IS  S   S+
Sbjct: 1034 GDNISIGSDHCSE 1046


>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
          Length = 1069

 Score =  605 bits (1560), Expect = e-173
 Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)

Query: 28   YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
            Y + EE P +V IG++  DL +       +T + +     ++G    ++I+  TGE+ T+
Sbjct: 36   YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87

Query: 88   GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
              RIDREKL  C  I  +  CF + EV+++ P + +  L + + ++ DINDN P FP+ V
Sbjct: 88   ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147

Query: 144  INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
            + +++ EN  + + Y LP A D D G NG++ YEL+          +S+     D    P
Sbjct: 148  LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207

Query: 194  EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
             G                                 + +L V    D E++   ++K    
Sbjct: 208  GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267

Query: 219  ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
                      ++V DGG P RSS AIL+V +TD NDN P F+++  E  + EN+  GT +
Sbjct: 268  REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327

Query: 269  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
             QL A D D+G N +I + F     ++ RRL  L+ T+G +++   +DREE    +  V+
Sbjct: 328  LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386

Query: 329  ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
            A D G  P   +A V++N+ D NDNVPSI+IR I   P+ D V  ++E++ ++T IAL+ 
Sbjct: 387  ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446

Query: 385  VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
            V+D+D   NG VTC    ++PF+L+P    +       + L T+  LDYE+T+E+ + ++
Sbjct: 447  VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506

Query: 438  AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
            A D+G P L+ +  L +KV D NDN P+F QS V V  PENN PG ++  V A DADSG 
Sbjct: 507  AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566

Query: 498  NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
            NA+I Y L       F++D  +G + V   LDRE+ D+Y F + AKD G+P L  + TV 
Sbjct: 567  NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626

Query: 558  VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
            V + D+NDN P F  + + FYV ENL  +  VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627  VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686

Query: 618  IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
            I++ TG I   +SFDRE Q +YTF VKA DGG   RS++A V++ V+D NDN P  +  P
Sbjct: 687  IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745

Query: 678  SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
             N SY L+ PS+N  TVV  V+A D+D G+NA++ YSIVGGN   LF ID  +G ++L+ 
Sbjct: 746  KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805

Query: 738  KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
            K      GLHR++V+ ND GQP S  +  +V++FVNESV+NAT I+  + +S   P+T +
Sbjct: 806  KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864

Query: 798  TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
                     +   + I++  VAG +TV+++I I  + R CR           K + ++ T
Sbjct: 865  IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924

Query: 857  PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
            P   ++     K KK KK   P  L  + VT+E +K +    D     L      +  +M
Sbjct: 925  PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977

Query: 917  GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
            G+Y  V       P SPDLARHYKS+SP P  Q+ P++P    KH  +Q+LP  NTFV A
Sbjct: 978  GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033

Query: 975  CDSISKCSSSSSD 987
             D+IS  S   S+
Sbjct: 1034 GDNISIGSDHCSE 1046


>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
          Length = 1200

 Score =  586 bits (1510), Expect = e-167
 Identities = 377/1025 (36%), Positives = 564/1025 (55%), Gaps = 55/1025 (5%)

Query: 28   YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
            Y + EE P +V IG++  DL +       +T + +     ++G    ++I+  TGE+ T+
Sbjct: 36   YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87

Query: 88   GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
              RIDREKL  C  I  +  CF + EV+++ P + +  L + + ++ DINDN P FP+ V
Sbjct: 88   ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147

Query: 144  INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 193
            + +++ EN  + + Y LP A D D G NG++ YEL++          S+     D    P
Sbjct: 148  LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207

Query: 194  EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 252
             G             +   D          GG   RSS   LQV+ T   +  P +  + 
Sbjct: 208  GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264

Query: 253  EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 312
              E  + EN+  GT + QL A D D+G N +I + F     ++ RRL  L+ T+G +++ 
Sbjct: 265  VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323

Query: 313  EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 369
              +DREE    +  V+A D G  P   +A V++N+ D NDNVPSI+IR I   P+ D V 
Sbjct: 324  HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383

Query: 370  -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETA 421
             ++E++ ++T IAL+ V+D+D   NG VTC    ++PF+L+P    +       + L T+
Sbjct: 384  NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443

Query: 422  AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
              LDYE+T+E+ + ++A D+G P L+ +  L +KV D NDN P+F QS V V  PENN P
Sbjct: 444  TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503

Query: 482  GIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
            G ++  V A DADSG NA+I Y L       F++D  +G + V   LDRE+ D+Y F + 
Sbjct: 504  GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563

Query: 542  AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGD 601
            AKD G+P L  + TV V + D+NDN P F  + + FYV ENL  +  VG++TV D D G 
Sbjct: 564  AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623

Query: 602  NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 661
            N+ ++L I + N+ F+I++ TG I   +SFDRE Q +YTF VKA DGG   RS++A V++
Sbjct: 624  NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683

Query: 662  NVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 721
             V+D NDN P  +  P N SY L+ PS+N  TVV  V+A D+D G+NA++ YSIVGGN  
Sbjct: 684  FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742

Query: 722  DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
             LF ID  +G ++L+ K      GLHR++V+ ND GQP S  +  +V++FVNESV+NAT 
Sbjct: 743  KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801

Query: 782  INELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 840
            I+  + +S   P+T +         +   + I++  VAG +TV+++I I  + R CR   
Sbjct: 802  IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861

Query: 841  HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
                    K + ++ TP   ++     K KK KK   P  L  + VT+E +K +    D 
Sbjct: 862  KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919

Query: 901  NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSK 959
                L      +  +MG+Y  V       P SPDLARHYKS+SP P  Q+ P++P    K
Sbjct: 920  VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970

Query: 960  HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRPTDSRTS 1017
            H  +Q+LP  NTFV A D+IS  S   S+    ++  Y    F  V  SV ++P D    
Sbjct: 971  HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQDPHQG 1030

Query: 1018 TIEIC 1022
            +++ C
Sbjct: 1031 SLQSC 1035


>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
           [Homo sapiens]
          Length = 936

 Score =  364 bits (934), Expect = e-100
 Identities = 234/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)

Query: 12  VLLACVVF----HSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
           ++L C+ F     +GA++ +Y+I EE+ +   +G++ KDL L+  P +     ++   + 
Sbjct: 17  LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71

Query: 68  KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 127
             G   L  +   +G + T G RIDRE+LCA   R   C   V   IL ++  +L  I  
Sbjct: 72  SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125

Query: 128 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 187
            + DINDNAP F A  +++ I EN A   ++ LP A+DPDVG+N +Q+Y+L  +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184

Query: 188 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 247
            V     G K P+L+++  LDREE+  + + +   DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244

Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
           VF   E  VS+PEN PVGT +  + ATD D G N ++ +SF  L      + F LN  TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303

Query: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367
            I I E LD EET  +++ + A DGG   A A VL+ V DVNDN P + I  + +PV   
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360

Query: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYE 427
              +E+ PL T +AL+ V D D++ NG+VTC     +PF+L     + + L     LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417

Query: 428 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK 487
               Y I + A D G PPL+  A   ++V D NDN P F+Q      IPENN+ G  +  
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477

Query: 488 VSAMDADSGPNAKINYLLGPDA------PPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
           V+A+D DS  NA+I Y L  D           S++  TG+L  ++  D E+  +    + 
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537

Query: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL---------- 591
           A D+G PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+          
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589

Query: 592 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 644
                +   D D G N+ ++  +L  ++   F +   TG +R   +         +  V 
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649

Query: 645 AEDGGRVSRSSSAKVTINVVD 665
            +D G+   S++  +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670



 Score =  240 bits (612), Expect = 6e-63
 Identities = 196/666 (29%), Positives = 314/666 (47%), Gaps = 63/666 (9%)

Query: 201 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 254
           LI    +DREE      +      + VED     R     +++ VTD NDN P F+   +
Sbjct: 88  LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142

Query: 255 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 314
           +V I EN   G       A D D+G N+   +  S        + F L   +    +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196

Query: 315 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
                  LDREE   H L++ ASDGG  L     +V V V D NDN P   +        
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP-FRLRPVFSNQFL--LETAA 422
             V + EN+P+ T++  +T TD+D   NG VT ++  ++P  +L     N++   ++ + 
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309

Query: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
            LDYE T  Y I++ A D G      +A + I V+D NDN+P  T + +   + E++  G
Sbjct: 310 NLDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLG 367

Query: 483 IQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
             +  ++  D DS  N ++   +    P   E S+D     L + + LDRE+   Y  T+
Sbjct: 368 TVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYY-RLVIHRALDREQVSSYNITV 426

Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
            A D G PPL++     + + D NDN P F+   Y  Y+PEN  R  ++  +T  DPD  
Sbjct: 427 TATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSK 486

Query: 601 DNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR 653
           +N+ +  S+ ++       +   +I+S TGV+    SFD E+       V A D G    
Sbjct: 487 ENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPL 546

Query: 654 SSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNA 709
           SS+  +++ V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+G NA
Sbjct: 547 SSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNA 606

Query: 710 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
            + Y ++  +   LFA+ + TG +         D     ++V   D GQP  L + V + 
Sbjct: 607 WLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLT 665

Query: 770 LFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 829
           + V +S+    ++ +L   S E+P   N+E +D++     Y+ + VAAV+      V++ 
Sbjct: 666 VAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVIVL 715

Query: 830 ITAVVR 835
           +   +R
Sbjct: 716 LAHRLR 721


>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
           [Homo sapiens]
          Length = 850

 Score =  364 bits (934), Expect = e-100
 Identities = 234/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)

Query: 12  VLLACVVF----HSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
           ++L C+ F     +GA++ +Y+I EE+ +   +G++ KDL L+  P +     ++   + 
Sbjct: 17  LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71

Query: 68  KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 127
             G   L  +   +G + T G RIDRE+LCA   R   C   V   IL ++  +L  I  
Sbjct: 72  SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125

Query: 128 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 187
            + DINDNAP F A  +++ I EN A   ++ LP A+DPDVG+N +Q+Y+L  +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184

Query: 188 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 247
            V     G K P+L+++  LDREE+  + + +   DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244

Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
           VF   E  VS+PEN PVGT +  + ATD D G N ++ +SF  L      + F LN  TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303

Query: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367
            I I E LD EET  +++ + A DGG   A A VL+ V DVNDN P + I  + +PV   
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360

Query: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYE 427
              +E+ PL T +AL+ V D D++ NG+VTC     +PF+L     + + L     LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417

Query: 428 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK 487
               Y I + A D G PPL+  A   ++V D NDN P F+Q      IPENN+ G  +  
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477

Query: 488 VSAMDADSGPNAKINYLLGPDA------PPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
           V+A+D DS  NA+I Y L  D           S++  TG+L  ++  D E+  +    + 
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537

Query: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL---------- 591
           A D+G PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+          
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589

Query: 592 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 644
                +   D D G N+ ++  +L  ++   F +   TG +R   +         +  V 
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649

Query: 645 AEDGGRVSRSSSAKVTINVVD 665
            +D G+   S++  +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670



 Score =  240 bits (612), Expect = 6e-63
 Identities = 196/666 (29%), Positives = 314/666 (47%), Gaps = 63/666 (9%)

Query: 201 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 254
           LI    +DREE      +      + VED     R     +++ VTD NDN P F+   +
Sbjct: 88  LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142

Query: 255 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 314
           +V I EN   G       A D D+G N+   +  S        + F L   +    +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196

Query: 315 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
                  LDREE   H L++ ASDGG  L     +V V V D NDN P   +        
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP-FRLRPVFSNQFL--LETAA 422
             V + EN+P+ T++  +T TD+D   NG VT ++  ++P  +L     N++   ++ + 
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309

Query: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
            LDYE T  Y I++ A D G      +A + I V+D NDN+P  T + +   + E++  G
Sbjct: 310 NLDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLG 367

Query: 483 IQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
             +  ++  D DS  N ++   +    P   E S+D     L + + LDRE+   Y  T+
Sbjct: 368 TVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYY-RLVIHRALDREQVSSYNITV 426

Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
            A D G PPL++     + + D NDN P F+   Y  Y+PEN  R  ++  +T  DPD  
Sbjct: 427 TATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSK 486

Query: 601 DNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR 653
           +N+ +  S+ ++       +   +I+S TGV+    SFD E+       V A D G    
Sbjct: 487 ENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPL 546

Query: 654 SSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNA 709
           SS+  +++ V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+G NA
Sbjct: 547 SSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNA 606

Query: 710 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
            + Y ++  +   LFA+ + TG +         D     ++V   D GQP  L + V + 
Sbjct: 607 WLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLT 665

Query: 770 LFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 829
           + V +S+    ++ +L   S E+P   N+E +D++     Y+ + VAAV+      V++ 
Sbjct: 666 VAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVIVL 715

Query: 830 ITAVVR 835
           +   +R
Sbjct: 716 LAHRLR 721


>gi|14589929 protocadherin 18 precursor [Homo sapiens]
          Length = 1135

 Score =  358 bits (920), Expect = 1e-98
 Identities = 229/662 (34%), Positives = 362/662 (54%), Gaps = 31/662 (4%)

Query: 8   YIFAVLLACVVFHSGAQEKN--YTIREEMPENVLIGDLLKDLN--LSLIPNKSLTTAMQF 63
           ++FA+L+  V F+     KN  Y I EE     +I  L +D+   L  +PN S    ++F
Sbjct: 12  FVFALLI--VSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPS---TVRF 66

Query: 64  KLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLV 123
           + + + G+ PL+ + ED GEI + GA IDRE+LC    ++ +C  E +V  LP E  +L 
Sbjct: 67  RAMQR-GNSPLLVVNEDNGEI-SIGATIDREQLCQ---KNLNCSIEFDVITLPTEHLQLF 121

Query: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
            I   + DINDN+P F  ++I I I E++A+ ++  L +A DPDVG N +  Y L  + +
Sbjct: 122 HIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSL-SAND 180

Query: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
            F ++V    +G K  +LIV +ELDRE K +Y +++   D G PQRS ++IL++S++D+N
Sbjct: 181 FFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSN 240

Query: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
           DN P F++    + + EN+PVGT +  L+ATD D G N KI +SFS+ VS      F ++
Sbjct: 241 DNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKID 300

Query: 304 ATTGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIV 361
           +  G +T+ + +D E T ++++ V A D G   +PA   +++ V DVNDN P I+I  + 
Sbjct: 301 SERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMS 360

Query: 362 NPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETA 421
               +   + E  P++T +AL+ V DKD+  NG + C       F+L+  + N +L+ T 
Sbjct: 361 PGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTN 420

Query: 422 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
           A LD E   EY++ ++A D G P L+      +++ D NDN P F +S     I ENNSP
Sbjct: 421 ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSP 480

Query: 482 GIQLTKVSAMDADSGPNAKINY------LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDK 535
           G  +T V+A D D G N ++ Y      +LG       ++D   G +  ++  D E+  +
Sbjct: 481 GAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQ 540

Query: 536 YLFTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPV-----FTHNEYNFYVPENLPRHGTV 589
             F + A+D G P  L SN TV ++IID+NDN PV       +N     +P+       V
Sbjct: 541 ITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHV 600

Query: 590 GLITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAED 647
             I   D D G N+ ++ +I+  N++  F ID ++  I  N+S D      +   V  +D
Sbjct: 601 TRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQD 660

Query: 648 GG 649
            G
Sbjct: 661 KG 662



 Score =  233 bits (594), Expect = 7e-61
 Identities = 187/628 (29%), Positives = 287/628 (45%), Gaps = 48/628 (7%)

Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVS 293
           ++V V D NDN P F  + I + I E+A VGT +    A D D+GEN+   +S S N   
Sbjct: 123 IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFF 182

Query: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARA---MVLVNVTDVND 350
           NI  R     A    + +   LDRE   +++L + ASD G+ P R+   ++ ++++D ND
Sbjct: 183 NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGV-PQRSGSSILKISISDSND 241

Query: 351 NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-CFTDHEIPFRLR 409
           N P+ + +  +      + L EN P+ T +  +  TD D   NG++   F+ H  P  + 
Sbjct: 242 NSPAFEQQSYI------IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIME 295

Query: 410 P--VFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFT 467
              + S +  L     +DYE TK Y I + A D G   +     + IKV D NDN P   
Sbjct: 296 TFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEIN 355

Query: 468 QSFVTVS------IPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGM 521
            + ++        I E +     +  V   D DSG N +I   L      +         
Sbjct: 356 INLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNY 415

Query: 522 LTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVP 580
           L +    LDREK  +Y  T++A+D G P L++     V I D NDN P F  + Y F + 
Sbjct: 416 LILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVIS 475

Query: 581 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 633
           EN      +  +T TDPD G+N  VT +IL+            TID   G I     FD 
Sbjct: 476 ENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDH 535

Query: 634 EKQESYTFYVKAEDGGRVSRS-SSAKVTINVVDVNDNKPVFIVPP-SNCSYELVLPS-TN 690
           E+    TF V+A DGG   +  S+  V + ++D NDN PV I P   N + E+ +P    
Sbjct: 536 EEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAE 595

Query: 691 PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 750
            G  V ++ A+D D+G+NAE+  +IV GN  ++F ID  + +I      D        + 
Sbjct: 596 SGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELS 655

Query: 751 VKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDY 810
           V   D G P  L + V++   + E   + T                +T +  VS  + D 
Sbjct: 656 VIIQDKGNP-QLHTKVLLKCMIFEYAESVT----------------STAMTSVSQASLDV 698

Query: 811 VKILVAAVAGTITVVVVIFITAVVRCRQ 838
             I++ ++     V++VI +    RC +
Sbjct: 699 SMIIIISLGAICAVLLVIMVLFATRCNR 726



 Score =  180 bits (456), Expect = 7e-45
 Identities = 158/567 (27%), Positives = 237/567 (41%), Gaps = 48/567 (8%)

Query: 299 LFHLNATTGLITIKEPLDREETPNHKL-LVLASDGGLMPARAMVL----VNVTDVNDNVP 353
           L  +N   G I+I   +DRE+     L   +  D   +P   + L    V V D+NDN P
Sbjct: 76  LLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSP 135

Query: 354 SIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTD----HEIPFRLR 409
                 I       + +SE+  + T+I L +  D D   N   T          I  R R
Sbjct: 136 QFSRSLI------PIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTR 189

Query: 410 PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 469
              +    L     LD E    Y ++L A+D G P  + S++L I + D NDN+P F Q 
Sbjct: 190 TDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQ 249

Query: 470 FVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE----FSLDCRTGMLTVV 525
              + + EN+  G  L  ++A D D G N KI Y       P+    F +D   G LT+ 
Sbjct: 250 SYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLF 309

Query: 526 KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHN------EYNFYV 579
           K++D E    Y   + A+D G   + ++  + + ++D NDN P    N      E   Y+
Sbjct: 310 KQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYI 369

Query: 580 PENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDS---QTGVIRPNISFDREKQ 636
            E  P    V L+ V D D G N  +    L  +  F +        +I  N + DREK+
Sbjct: 370 FEGDPIDTFVALVRVQDKDSGLNGEIVCK-LHGHGHFKLQKTYENNYLILTNATLDREKR 428

Query: 637 ESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTN-PGTVV 695
             Y+  V AED G  S S+    T+ + D+NDN P F        YE V+   N PG  +
Sbjct: 429 SEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHF----QRSRYEFVISENNSPGAYI 484

Query: 696 FQVIAVDNDTGMNAEVRYS-----IVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 750
             V A D D G N +V Y+     I+G +      ID   G I  +   D  ++     +
Sbjct: 485 TTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFV 544

Query: 751 VKANDLGQPDSLFS-VVIVNLFVNESVTNATLINELVRKSTEAPVTPN--------TEIA 801
           V+A D G P  L S   +V   ++E+     +I   +R +T     P         T I 
Sbjct: 545 VEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIR 604

Query: 802 DVSSPTSDYVKILVAAVAGTITVVVVI 828
            +   +    ++  A VAG    + +I
Sbjct: 605 AIDRDSGVNAELSCAIVAGNEENIFII 631


>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  357 bits (915), Expect = 4e-98
 Identities = 223/683 (32%), Positives = 354/683 (51%), Gaps = 51/683 (7%)

Query: 6   GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
           G  +  +LL   ++ +G  +  Y++ EE+ +   +GD+ +DL L   P +     ++   
Sbjct: 12  GLVLLGILLG-TLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR--- 65

Query: 66  VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
           +   G   L  +   +G + T G RIDRE+LC G  +      ++ + IL ++  ++  +
Sbjct: 66  IIPRGRTQLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGV 119

Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
              + DINDNAP F  + + I I EN+A   ++ LP A DPD+G N +Q+YEL  + + F
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-F 178

Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
            L V    +G K P+L++++ LDREEK  + + +   DGG P R+ TA ++V V D NDN
Sbjct: 179 SLIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDN 238

Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
            P F + E   S+PEN  +GT +  ++ATD D G NA++ +SF   V + A ++F L+  
Sbjct: 239 APAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCN 297

Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
           +G I+    LD EE+  +++ V A D     ARA VL+ V DVNDN P + +  + + V 
Sbjct: 298 SGTISTIGELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV- 356

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
                 EN P  T IAL+ V D+D++ NG+V CF    +PF+L   + N + L T   LD
Sbjct: 357 -----PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLD 411

Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
            E    Y I + A D G PPL+    + + V D NDN PVF Q+  +  IPENN  G+ L
Sbjct: 412 REQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSL 471

Query: 486 TKVSAMDADSGPNAKINYLL------GPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
             V+A D D   NA+I Y L      G       S++  TG+L  +   D E+       
Sbjct: 472 VSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVK 531

Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
           ++A+DNG PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+        
Sbjct: 532 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAE 583

Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
                  +   D D G N+ ++  +L  ++   F++   TG +R   +         +  
Sbjct: 584 PGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLV 643

Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
           V  +D G+   S++  +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666



 Score =  246 bits (629), Expect = 6e-65
 Identities = 197/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)

Query: 201 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
           L+    +DREE     +K ++  D     +     ++V V D NDN P F+E+E+E+ I 
Sbjct: 84  LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143

Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 315
           ENA         HA D DIG+N+   +  S    N    L   N   G     + +K  L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200

Query: 316 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 373
           DREE   H L++ ASDGG  +    A + V V D NDN P+        P     V  EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254

Query: 374 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTK 430
           + L T++ ++  TD D   N  V  ++   +  +   VF    N   + T   LD+E + 
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313

Query: 431 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSA 490
            Y +++ A D      +  A + I V D NDNAP    + +  S+PEN+  G  +  ++ 
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371

Query: 491 MDADSGPNAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 547
            D DS  N ++   +  + P  F L+   G    L     LDRE+   Y  T+ A D G 
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429

Query: 548 PPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 607
           PPL++   + +++ D NDN PVF    Y+ Y+PEN PR  ++  +T  DPD  +N+ +T 
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489

Query: 608 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
           S+ +        +   +I+S TGV+    SFD E+       V A D G    SS+  ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549

Query: 661 INVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
           + V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609

Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
             +   LF++   TG +         D     ++V   D GQP  L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668

Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 835
               ++ +L   S E+P   N+E +D++     Y+ + VAAV+      V++ +   +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717


>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  357 bits (915), Expect = 4e-98
 Identities = 223/683 (32%), Positives = 354/683 (51%), Gaps = 51/683 (7%)

Query: 6   GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
           G  +  +LL   ++ +G  +  Y++ EE+ +   +GD+ +DL L   P +     ++   
Sbjct: 12  GLVLLGILLG-TLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR--- 65

Query: 66  VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
           +   G   L  +   +G + T G RIDRE+LC G  +      ++ + IL ++  ++  +
Sbjct: 66  IIPRGRTQLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGV 119

Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
              + DINDNAP F  + + I I EN+A   ++ LP A DPD+G N +Q+YEL  + + F
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-F 178

Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
            L V    +G K P+L++++ LDREEK  + + +   DGG P R+ TA ++V V D NDN
Sbjct: 179 SLIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDN 238

Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
            P F + E   S+PEN  +GT +  ++ATD D G NA++ +SF   V + A ++F L+  
Sbjct: 239 APAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCN 297

Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
           +G I+    LD EE+  +++ V A D     ARA VL+ V DVNDN P + +  + + V 
Sbjct: 298 SGTISTIGELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV- 356

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
                 EN P  T IAL+ V D+D++ NG+V CF    +PF+L   + N + L T   LD
Sbjct: 357 -----PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLD 411

Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
            E    Y I + A D G PPL+    + + V D NDN PVF Q+  +  IPENN  G+ L
Sbjct: 412 REQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSL 471

Query: 486 TKVSAMDADSGPNAKINYLL------GPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
             V+A D D   NA+I Y L      G       S++  TG+L  +   D E+       
Sbjct: 472 VSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVK 531

Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
           ++A+DNG PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+        
Sbjct: 532 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAE 583

Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
                  +   D D G N+ ++  +L  ++   F++   TG +R   +         +  
Sbjct: 584 PGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLV 643

Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
           V  +D G+   S++  +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666



 Score =  246 bits (629), Expect = 6e-65
 Identities = 197/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)

Query: 201 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
           L+    +DREE     +K ++  D     +     ++V V D NDN P F+E+E+E+ I 
Sbjct: 84  LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143

Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 315
           ENA         HA D DIG+N+   +  S    N    L   N   G     + +K  L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200

Query: 316 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 373
           DREE   H L++ ASDGG  +    A + V V D NDN P+        P     V  EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254

Query: 374 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTK 430
           + L T++ ++  TD D   N  V  ++   +  +   VF    N   + T   LD+E + 
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313

Query: 431 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSA 490
            Y +++ A D      +  A + I V D NDNAP    + +  S+PEN+  G  +  ++ 
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371

Query: 491 MDADSGPNAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 547
            D DS  N ++   +  + P  F L+   G    L     LDRE+   Y  T+ A D G 
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429

Query: 548 PPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 607
           PPL++   + +++ D NDN PVF    Y+ Y+PEN PR  ++  +T  DPD  +N+ +T 
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489

Query: 608 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
           S+ +        +   +I+S TGV+    SFD E+       V A D G    SS+  ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549

Query: 661 INVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
           + V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609

Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
             +   LF++   TG +         D     ++V   D GQP  L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668

Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 835
               ++ +L   S E+P   N+E +D++     Y+ + VAAV+      V++ +   +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717


>gi|94538350 protocadherin 17 precursor [Homo sapiens]
          Length = 1159

 Score =  355 bits (912), Expect = 9e-98
 Identities = 238/675 (35%), Positives = 352/675 (52%), Gaps = 49/675 (7%)

Query: 27  NYTIREEMPENVLIGDLLKDLNLSL-IPNKSLTTAMQFKL----VYKTGDVPLIRIEEDT 81
           NY++ EE     +IG++ +D  L   +P        + K     V +     L+ ++ D+
Sbjct: 22  NYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVDADS 81

Query: 82  GEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPA 141
           G ++T   RIDRE LC     +  C   +EV     EI  ++K+   I+DINDNAP F +
Sbjct: 82  GLLYTK-QRIDRESLCR---HNAKCQLSLEVFANDKEIC-MIKVE--IQDINDNAPSFSS 134

Query: 142 TVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN-IFGLDVIETPEGDKMPQ 200
             I + I EN+A  +++ L +A DPD G NG++ Y L +  + +FGLDV    +G K P+
Sbjct: 135 DQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPE 194

Query: 201 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 260
           L++QK LDRE+++ + + +   DGG P RS+T  + V V D+NDN PVF+     V +PE
Sbjct: 195 LVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPE 254

Query: 261 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 320
           NAP+GT V  L+ATDAD G N ++ +SFS+ V +  R LF ++  TGLI +K  LD EE 
Sbjct: 255 NAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEEN 314

Query: 321 PNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 378
              ++ V A D G   +PA   V V + D NDN PSI    +         LSE  P  T
Sbjct: 315 GMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG-----ALSEAAPPGT 369

Query: 379 KIALITVTDKDADHNGRVTCFT---------------DHEIPFRLRPVFSNQFLLETAAY 423
            IAL+ VTD+D+  NG++ C                    +PF+L   + N + + T   
Sbjct: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429

Query: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
           LD E+  EY + ++A D G PPLN +    IK+ DENDN P FT+    + + ENN PG 
Sbjct: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489

Query: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSL------DCRTGMLTVVKKLDREKEDKYL 537
            L  V A D D G N  ++Y + P    + S+      +   G +  ++  + E+   + 
Sbjct: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549

Query: 538 FTILAKDNGVPP-LTSNVTVFVSIIDQNDNSPVFT-----HNEYNFYVPENLPRHGTVGL 591
           F +LAKD+G P  L SN TV V+++D NDN+PV       ++     VP N      V  
Sbjct: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVST 609

Query: 592 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 649
           +   D D+G++  +T  I+D NDD  F ID  +G IR    F  +        VK  D G
Sbjct: 610 VRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHG 669

Query: 650 RVSRSSSAKVTINVV 664
           + + S+ AK+ I  V
Sbjct: 670 KPTLSAVAKLIIRSV 684



 Score =  248 bits (634), Expect = 2e-65
 Identities = 233/816 (28%), Positives = 357/816 (43%), Gaps = 101/816 (12%)

Query: 136 APLFPATVINISIPENSAINS-----------KYTLPAAVDPDVGINGVQNYELIKSQNI 184
           AP      +N S+PE     +           +  LP A     G +   +Y ++++   
Sbjct: 13  APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72

Query: 185 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 244
             LDV +   G     L  ++ +DRE    +  K ++    F       +++V + D ND
Sbjct: 73  HLLDV-DADSG----LLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDIND 127

Query: 245 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 304
           N P F   +IE+ I ENA  GT      A D D GEN    +    L++     LF L+ 
Sbjct: 128 NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTY----LLTRDDHGLFGLDV 183

Query: 305 TTG-------LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSI 355
            +         + I++ LDRE+  +H L++ A DGG  P  A V +NV   D NDN P  
Sbjct: 184 KSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVF 243

Query: 356 DI-RYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS- 413
           +   Y+V        L EN PL T +  +  TD D   NG V       +P R+R +FS 
Sbjct: 244 EAPSYLVE-------LPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSI 296

Query: 414 --NQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFV 471
                L+     LDYE      I + A D G  P+     + +K+ D NDNAP     FV
Sbjct: 297 DPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSI--GFV 354

Query: 472 TV---SIPENNSPGIQLTKVSAMDADSGPNAKINY-------------LLGPDAPPEFSL 515
           +V   ++ E   PG  +  V   D DSG N ++               L GP     F L
Sbjct: 355 SVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL 414

Query: 516 DCR-TGMLTVV--KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 572
           +       TVV  + LDRE +D+Y  TI+A+D G PPL S  +  + I+D+NDN P FT 
Sbjct: 415 EENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTK 474

Query: 573 NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD-------FTIDSQTGVI 625
             Y   V EN      +G +   DPD G N  V+ SIL  +          +++   G I
Sbjct: 475 GLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAI 534

Query: 626 RPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFIVPP-SNCSYE 683
               SF+ E+ +++ F V A+D G  +   S+A V + V+DVNDN PV ++P   N + E
Sbjct: 535 YALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAE 594

Query: 684 LVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKC--D 740
           L +P +   G +V  V A+D+D G +  + Y IV GN   LF ID  +G I  +     D
Sbjct: 595 LQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWED 654

Query: 741 VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEI 800
           VT   +  ++VK  D G+P                    + + +L+ +S    +      
Sbjct: 655 VTP--VVELVVKVTDHGKP------------------TLSAVAKLIIRSVSGSLPEGVPR 694

Query: 801 ADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPE 860
            +      D    L+  ++    +++   IT  V+C+        ++NK+   +     E
Sbjct: 695 VNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCK--------RENKEIRTYNCRIAE 746

Query: 861 NRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDV 896
                +   K KKKK +  +++L    +EE  A +V
Sbjct: 747 YSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAMNV 782


>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
          Length = 1101

 Score =  352 bits (903), Expect = 1e-96
 Identities = 235/669 (35%), Positives = 358/669 (53%), Gaps = 36/669 (5%)

Query: 12  VLLACVVFHSGAQEKN--YTIREEMPENVLIGDLLKDLN---LSLIPNKSLTTAMQFKLV 66
           +LL  +++   A   N  Y++ EE     +I ++ KD      +L P +    A  F++V
Sbjct: 9   LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQ----ASAFRVV 64

Query: 67  YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 126
             +    L+ I   +G +  T  +IDR+ LC   P+   C   +EV     EI  ++K+ 
Sbjct: 65  SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118

Query: 127 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 186
             I+D+NDNAP FPA  I + I E ++  ++  L +A DPD G  GVQ YEL  ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175

Query: 187 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 246
           L++    +G +  +L+V+K LDRE +  Y  ++   DGG P R  T  L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235

Query: 247 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 306
           PVF E+   VS+PEN+P  T V +L+A+D D G N ++ +SF   V++  R LF ++  +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295

Query: 307 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 364
           GL+T+   LD EE   ++L V A D G   +PA   V V+V D NDN P I+   +++  
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352

Query: 365 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYL 424
           ++ V +SE+ P    IAL+ V+D+D+  NGRV C     +PFRL+   S   +L     L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTIL-VDGRL 411

Query: 425 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
           D E   +Y + + A D G P L  +    + + DENDN P F++ +  V + ENN+PG  
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471

Query: 485 LTKVSAMDADSGPNAKINYLLGP----DAP--PEFSLDCRTGMLTVVKKLDREKEDKYLF 538
           L  VSA D D G N  ++Y + P    D P     S++  +G +  ++  + E+   + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531

Query: 539 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYNFYVPENLPRHGTVGLIT 593
            +LAKD G+P L SN TV V I+D NDN+PV T     +     Y+P N      V ++ 
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591

Query: 594 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 652
             D D G+N  VT  + + +   F ID   G +R   +F    + SY   V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651

Query: 653 RSSSAKVTI 661
            S+SA V I
Sbjct: 652 LSASALVLI 660



 Score =  215 bits (547), Expect = 2e-55
 Identities = 200/742 (26%), Positives = 315/742 (42%), Gaps = 74/742 (9%)

Query: 201 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 260
           L+ ++++DR+       K  +            +++V + D NDN P F   +IE+ I E
Sbjct: 81  LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140

Query: 261 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 313
            A  GT +    A D D G      +  +         LF L   T         + +++
Sbjct: 141 AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194

Query: 314 PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 371
            LDRE   ++   + A DGG  P    V   + VTD NDN P      + +     V + 
Sbjct: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248

Query: 372 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYES 428
           EN P NT +  +  +D D   NG+V       +  R R +F    +  L+     LDYE 
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308

Query: 429 TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 485
              Y + + A D G   +     + + V D NDN PV     V    V + E+  PG  +
Sbjct: 309 GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368

Query: 486 TKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDN 545
             V   D DSG N ++   L  + P           + V  +LDRE+ D+Y  TI A+D 
Sbjct: 369 ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428

Query: 546 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV 605
           GVP L S  +  V I D+NDN P F+   Y   V EN      +  ++  DPD G N +V
Sbjct: 429 GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488

Query: 606 TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 658
           +  I+             +I+  +G I    SF+ E+ +++ F V A+DGG  S  S+A 
Sbjct: 489 SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548

Query: 659 VTINVVDVNDNKPVFIVPP-SNCSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
           V + ++DVNDN PV   PP  N + E+ +P ++  G +V  V A D D G N  V Y + 
Sbjct: 549 VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608

Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
            G+ R  F IDQ  G +        +    + ++V A+D G+  SL +  +V ++++ ++
Sbjct: 609 EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666

Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 836
                                   A  S  + +   I + A+     ++ V  I   ++C
Sbjct: 667 D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703

Query: 837 RQAPHLKAAQKNKQNSEWATPNPENRQMIM--MKKKKKKKKHSPKNLLLNFVTIEETKAD 894
           +           + N E  T N    +      KK  KKKK S  ++ L    +EET   
Sbjct: 704 K-----------RDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKM 752

Query: 895 DVDSDGNRVTLDLPIDLEEQTM 916
           +V S  +  +     D  +QT+
Sbjct: 753 NVVSCSSLTSSLNYFDYHQQTL 774


>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
          Length = 1100

 Score =  352 bits (903), Expect = 1e-96
 Identities = 235/669 (35%), Positives = 358/669 (53%), Gaps = 36/669 (5%)

Query: 12  VLLACVVFHSGAQEKN--YTIREEMPENVLIGDLLKDLN---LSLIPNKSLTTAMQFKLV 66
           +LL  +++   A   N  Y++ EE     +I ++ KD      +L P +    A  F++V
Sbjct: 9   LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQ----ASAFRVV 64

Query: 67  YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 126
             +    L+ I   +G +  T  +IDR+ LC   P+   C   +EV     EI  ++K+ 
Sbjct: 65  SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118

Query: 127 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 186
             I+D+NDNAP FPA  I + I E ++  ++  L +A DPD G  GVQ YEL  ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175

Query: 187 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 246
           L++    +G +  +L+V+K LDRE +  Y  ++   DGG P R  T  L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235

Query: 247 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 306
           PVF E+   VS+PEN+P  T V +L+A+D D G N ++ +SF   V++  R LF ++  +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295

Query: 307 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 364
           GL+T+   LD EE   ++L V A D G   +PA   V V+V D NDN P I+   +++  
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352

Query: 365 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYL 424
           ++ V +SE+ P    IAL+ V+D+D+  NGRV C     +PFRL+   S   +L     L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTIL-VDGRL 411

Query: 425 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
           D E   +Y + + A D G P L  +    + + DENDN P F++ +  V + ENN+PG  
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471

Query: 485 LTKVSAMDADSGPNAKINYLLGP----DAP--PEFSLDCRTGMLTVVKKLDREKEDKYLF 538
           L  VSA D D G N  ++Y + P    D P     S++  +G +  ++  + E+   + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531

Query: 539 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYNFYVPENLPRHGTVGLIT 593
            +LAKD G+P L SN TV V I+D NDN+PV T     +     Y+P N      V ++ 
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591

Query: 594 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 652
             D D G+N  VT  + + +   F ID   G +R   +F    + SY   V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651

Query: 653 RSSSAKVTI 661
            S+SA V I
Sbjct: 652 LSASALVLI 660



 Score =  215 bits (547), Expect = 2e-55
 Identities = 200/742 (26%), Positives = 315/742 (42%), Gaps = 74/742 (9%)

Query: 201 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 260
           L+ ++++DR+       K  +            +++V + D NDN P F   +IE+ I E
Sbjct: 81  LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140

Query: 261 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 313
            A  GT +    A D D G      +  +         LF L   T         + +++
Sbjct: 141 AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194

Query: 314 PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 371
            LDRE   ++   + A DGG  P    V   + VTD NDN P      + +     V + 
Sbjct: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248

Query: 372 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYES 428
           EN P NT +  +  +D D   NG+V       +  R R +F    +  L+     LDYE 
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308

Query: 429 TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 485
              Y + + A D G   +     + + V D NDN PV     V    V + E+  PG  +
Sbjct: 309 GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368

Query: 486 TKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDN 545
             V   D DSG N ++   L  + P           + V  +LDRE+ D+Y  TI A+D 
Sbjct: 369 ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428

Query: 546 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV 605
           GVP L S  +  V I D+NDN P F+   Y   V EN      +  ++  DPD G N +V
Sbjct: 429 GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488

Query: 606 TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 658
           +  I+             +I+  +G I    SF+ E+ +++ F V A+DGG  S  S+A 
Sbjct: 489 SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548

Query: 659 VTINVVDVNDNKPVFIVPP-SNCSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
           V + ++DVNDN PV   PP  N + E+ +P ++  G +V  V A D D G N  V Y + 
Sbjct: 549 VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608

Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
            G+ R  F IDQ  G +        +    + ++V A+D G+  SL +  +V ++++ ++
Sbjct: 609 EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666

Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 836
                                   A  S  + +   I + A+     ++ V  I   ++C
Sbjct: 667 D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703

Query: 837 RQAPHLKAAQKNKQNSEWATPNPENRQMIM--MKKKKKKKKHSPKNLLLNFVTIEETKAD 894
           +           + N E  T N    +      KK  KKKK S  ++ L    +EET   
Sbjct: 704 K-----------RDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKM 752

Query: 895 DVDSDGNRVTLDLPIDLEEQTM 916
           +V S  +  +     D  +QT+
Sbjct: 753 NVVSCSSLTSSLNYFDYHQQTL 774


>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
           [Homo sapiens]
          Length = 932

 Score =  351 bits (900), Expect = 2e-96
 Identities = 230/683 (33%), Positives = 354/683 (51%), Gaps = 51/683 (7%)

Query: 6   GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
           G ++ ++LL    + + A    Y++ EE  +   +GD+ KDL L   P +     ++   
Sbjct: 12  GFFLLSILLG-TPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR--- 65

Query: 66  VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
           +   G   L  + + +G + T G RIDRE++CA   R   C   V   IL ++   L  I
Sbjct: 66  IISRGRTQLFALNQRSGSLVTAG-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPI 119

Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
              I DINDN P F    IN+ I EN+A   ++ L  A DPDVG N +Q+Y+L  +++ F
Sbjct: 120 DVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-F 178

Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
            L V    +  K P+L++++ LDREE+  + + +   DGG P RSSTA +QV+V D ND+
Sbjct: 179 SLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDH 238

Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
            PVF   + +V++PEN PVGT +  +HA D D G N ++ +SF  +   + + +FHLN+ 
Sbjct: 239 TPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSL 297

Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
           TG I+  E LD EET  +++ V A DG     +A VL+ V DVNDN P + +  + + + 
Sbjct: 298 TGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI- 356

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
                 E+ PL T IAL  + D+D+  NG VTC     +PF+L     N + L T   LD
Sbjct: 357 -----PEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLD 411

Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
            E+   Y I L A D G PPL++   +F++V D NDN P F  S  +V I ENN  G  +
Sbjct: 412 RETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASI 471

Query: 486 TKVSAMDADSGPNAKINYLLGPD----APPE--FSLDCRTGMLTVVKKLDREKEDKYLFT 539
             V+A D DS  NA+I Y L  D    AP     S++  TG+L  ++  D E+  +    
Sbjct: 472 FLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLR 531

Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
           + A D+G PPL+SN+++ + ++DQNDN P   +          LP  G+ G+        
Sbjct: 532 VTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILY--------PALPTDGSTGMELAPRSAE 583

Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
                  +   D D G N+ ++  +L  ++   F +   TG +R   +         +  
Sbjct: 584 PGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643

Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
           V  +D G+   S++  +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666



 Score =  247 bits (631), Expect = 4e-65
 Identities = 184/567 (32%), Positives = 269/567 (47%), Gaps = 42/567 (7%)

Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
           + V + D NDN P F   EI V I EN   G       A D D+G N+   +  S     
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173

Query: 295 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 345
              R F L   +G    K P       LDREE   H L++ ASDGG  P  + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232

Query: 346 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 405
            DVND+ P   +          V + EN+P+ T++  +   D D   NG VT ++  +I 
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285

Query: 406 FRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 462
            +L  +F    L   + T   LDYE T  Y +++ A D   P     A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343

Query: 463 APVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTG 520
           AP  T + ++ SIPE+   G  +      D DSG N ++   +  + P   E S+D    
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403

Query: 521 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVP 580
           ++T  K LDRE    Y  T+ A D G PPL+    +F+ + D NDN P F H+ Y+ Y+ 
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462

Query: 581 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 633
           EN PR  ++ L+T  D D  DN+ +T S+ ++       +   +I+S TGV+    SFD 
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522

Query: 634 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPST 689
           E+       V A D G    SS+  +++ V+D NDN P  + P      +   EL   S 
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582

Query: 690 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 749
            PG +V +V+AVD D+G NA + Y ++  +   LFA+   TG +         D     +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642

Query: 750 LVKANDLGQPDSLFSVVIVNLFVNESV 776
           +V   D GQP  L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668



 Score =  108 bits (271), Expect = 2e-23
 Identities = 87/280 (31%), Positives = 131/280 (46%), Gaps = 16/280 (5%)

Query: 513 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV-TVFVSIIDQNDNSPVFT 571
           F+L+ R+G L    ++DRE+        L   N +     N+  + V IID NDN P F 
Sbjct: 75  FALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFL 134

Query: 572 HNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNIS- 630
             E N  + EN        L    DPD G NS  +   L  N  F++  Q+G        
Sbjct: 135 TEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQ-LSPNRHFSLAVQSGDDETKYPE 193

Query: 631 ------FDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYEL 684
                  DRE++  +   + A DGG   RSS+A + + VVDVND+ PVF +P     Y++
Sbjct: 194 LVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLP----QYQV 249

Query: 685 VLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSI--VGGNTRDLFAIDQETGNITLMEKCDV 741
            +P   P GT +  V A+D D G+N EV YS   +      +F ++  TG I+ +E  D 
Sbjct: 250 TVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGLDY 309

Query: 742 TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
            +   + + V+A D     +   V+I  L VN++    T+
Sbjct: 310 EETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTM 349


>gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precursor
           [Homo sapiens]
          Length = 817

 Score =  351 bits (900), Expect = 2e-96
 Identities = 230/683 (33%), Positives = 354/683 (51%), Gaps = 51/683 (7%)

Query: 6   GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
           G ++ ++LL    + + A    Y++ EE  +   +GD+ KDL L   P +     ++   
Sbjct: 12  GFFLLSILLG-TPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR--- 65

Query: 66  VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
           +   G   L  + + +G + T G RIDRE++CA   R   C   V   IL ++   L  I
Sbjct: 66  IISRGRTQLFALNQRSGSLVTAG-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPI 119

Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
              I DINDN P F    IN+ I EN+A   ++ L  A DPDVG N +Q+Y+L  +++ F
Sbjct: 120 DVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-F 178

Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
            L V    +  K P+L++++ LDREE+  + + +   DGG P RSSTA +QV+V D ND+
Sbjct: 179 SLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDH 238

Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
            PVF   + +V++PEN PVGT +  +HA D D G N ++ +SF  +   + + +FHLN+ 
Sbjct: 239 TPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSL 297

Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
           TG I+  E LD EET  +++ V A DG     +A VL+ V DVNDN P + +  + + + 
Sbjct: 298 TGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI- 356

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
                 E+ PL T IAL  + D+D+  NG VTC     +PF+L     N + L T   LD
Sbjct: 357 -----PEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLD 411

Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
            E+   Y I L A D G PPL++   +F++V D NDN P F  S  +V I ENN  G  +
Sbjct: 412 RETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASI 471

Query: 486 TKVSAMDADSGPNAKINYLLGPD----APPE--FSLDCRTGMLTVVKKLDREKEDKYLFT 539
             V+A D DS  NA+I Y L  D    AP     S++  TG+L  ++  D E+  +    
Sbjct: 472 FLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLR 531

Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
           + A D+G PPL+SN+++ + ++DQNDN P   +          LP  G+ G+        
Sbjct: 532 VTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILY--------PALPTDGSTGMELAPRSAE 583

Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
                  +   D D G N+ ++  +L  ++   F +   TG +R   +         +  
Sbjct: 584 PGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643

Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
           V  +D G+   S++  +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666



 Score =  247 bits (631), Expect = 4e-65
 Identities = 184/567 (32%), Positives = 269/567 (47%), Gaps = 42/567 (7%)

Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
           + V + D NDN P F   EI V I EN   G       A D D+G N+   +  S     
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173

Query: 295 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 345
              R F L   +G    K P       LDREE   H L++ ASDGG  P  + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232

Query: 346 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 405
            DVND+ P   +          V + EN+P+ T++  +   D D   NG VT ++  +I 
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285

Query: 406 FRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 462
            +L  +F    L   + T   LDYE T  Y +++ A D   P     A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343

Query: 463 APVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTG 520
           AP  T + ++ SIPE+   G  +      D DSG N ++   +  + P   E S+D    
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403

Query: 521 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVP 580
           ++T  K LDRE    Y  T+ A D G PPL+    +F+ + D NDN P F H+ Y+ Y+ 
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462

Query: 581 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 633
           EN PR  ++ L+T  D D  DN+ +T S+ ++       +   +I+S TGV+    SFD 
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522

Query: 634 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPST 689
           E+       V A D G    SS+  +++ V+D NDN P  + P      +   EL   S 
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582

Query: 690 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 749
            PG +V +V+AVD D+G NA + Y ++  +   LFA+   TG +         D     +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642

Query: 750 LVKANDLGQPDSLFSVVIVNLFVNESV 776
           +V   D GQP  L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668



 Score =  108 bits (271), Expect = 2e-23
 Identities = 87/280 (31%), Positives = 131/280 (46%), Gaps = 16/280 (5%)

Query: 513 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV-TVFVSIIDQNDNSPVFT 571
           F+L+ R+G L    ++DRE+        L   N +     N+  + V IID NDN P F 
Sbjct: 75  FALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFL 134

Query: 572 HNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNIS- 630
             E N  + EN        L    DPD G NS  +   L  N  F++  Q+G        
Sbjct: 135 TEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQ-LSPNRHFSLAVQSGDDETKYPE 193

Query: 631 ------FDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYEL 684
                  DRE++  +   + A DGG   RSS+A + + VVDVND+ PVF +P     Y++
Sbjct: 194 LVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLP----QYQV 249

Query: 685 VLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSI--VGGNTRDLFAIDQETGNITLMEKCDV 741
            +P   P GT +  V A+D D G+N EV YS   +      +F ++  TG I+ +E  D 
Sbjct: 250 TVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGLDY 309

Query: 742 TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
            +   + + V+A D     +   V+I  L VN++    T+
Sbjct: 310 EETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTM 349


>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
           [Homo sapiens]
          Length = 810

 Score =  349 bits (895), Expect = 9e-96
 Identities = 229/661 (34%), Positives = 344/661 (52%), Gaps = 44/661 (6%)

Query: 23  AQEKNYTIREEMPENVLIGDLLKDLNLSL--IPNKSLTTAMQFKLVYKTGDVPLIRIEED 80
           +Q+  YTI EE+     +G L KDL LS+  +P + L  + +              +  +
Sbjct: 28  SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77

Query: 81  TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 139
           +G++   G RIDREK+C    R   C  E E VA  P  +F +V +   I+DINDNAP F
Sbjct: 78  SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130

Query: 140 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 199
            A  I++ I E++    K++L +A D DV  N ++ Y +  +Q  F L   E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189

Query: 200 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
            L+++K LDRE + ++ + +   DGG P  S T  + + VTD NDN PVF +    VS+ 
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249

Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 319
           EN P GTSV ++ ATD D G NA+I ++F N  S I+  LF+LN  TG IT    LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307

Query: 320 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 379
           T  + L V A DGG+  A   V + + D NDN P +      N +       E+  L T 
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361

Query: 380 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAA 439
           IALI V DKD+  NG VTC+T  E+PF+L     N + L  A  L+ E T +Y + ++A 
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421

Query: 440 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNA 499
           D GKP L+    + + + D NDNAPVF Q+   V + ENN PG  + +VSA D D GPN 
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481

Query: 500 KINY-LLGPDAPPE-----FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 553
           +++Y +L  D  P       S+  ++G++   +  D E+   +  T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541

Query: 554 VTVFVSIIDQNDNSPVFTH-------NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVT 606
           V++ V + D NDN+P   +       +     VP        V  +   D D G N+ ++
Sbjct: 542 VSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLS 601

Query: 607 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 664
             +L  ++   F++  +TG +R   +            V   DGG+   S++A + +   
Sbjct: 602 YHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFA 661

Query: 665 D 665
           D
Sbjct: 662 D 662



 Score =  237 bits (604), Expect = 5e-62
 Identities = 192/711 (27%), Positives = 332/711 (46%), Gaps = 57/711 (8%)

Query: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 202
           I  +IPE  A  S+     A D  + +  +   +L + +++ F + +     GD    L+
Sbjct: 31  IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82

Query: 203 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 261
           V   +DRE+     ++  +E     +       + V + D NDN P F    I++ I E+
Sbjct: 83  VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142

Query: 262 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 320
           A  G   +   A DAD+ G + K++    N   +++ +     +   ++ +++PLDRE  
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202

Query: 321 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 378
            +H+L++ A DGG  P      + + VTD NDN P      + +     V L EN+P  T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256

Query: 379 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLL 437
            +  +  TD+D   N  +T  F +  I   L  +  N   + T   LD+E T  Y + + 
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316

Query: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
           A D G    + +    I++ DENDNAP  T    +  IPE++  G  +  +   D DSG 
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374

Query: 498 NAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV 554
           N  +      + P  F L+  +     L +   L+RE+   Y  TI+A D G P L+S  
Sbjct: 375 NGMVTCYTQEEVP--FKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT 432

Query: 555 TVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDEND 614
           ++ + I D NDN+PVF    Y  +V EN P   ++  ++ +DPD G N  V+ SIL  + 
Sbjct: 433 SITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDL 492

Query: 615 D-------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVN 667
           +        ++  Q+GV+    +FD E+  ++   ++A D G  + S++  + + V D+N
Sbjct: 493 EPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLN 552

Query: 668 DNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
           DN P  + P      +  +++V  +  PG +V +V+AVD D+G NA + Y ++  +   L
Sbjct: 553 DNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL 612

Query: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
           F++   TG +         D    R+LV   D GQP    +  +  +F       A  + 
Sbjct: 613 FSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIF-------ADSLQ 665

Query: 784 ELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 834
           E++   ++ P        + S P ++    LV A+A    ++ V+F+ AV+
Sbjct: 666 EVLPDLSDRP--------EPSDPQTELQFYLVVALA----LISVLFLLAVI 704


>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
           [Homo sapiens]
          Length = 927

 Score =  349 bits (895), Expect = 9e-96
 Identities = 229/661 (34%), Positives = 344/661 (52%), Gaps = 44/661 (6%)

Query: 23  AQEKNYTIREEMPENVLIGDLLKDLNLSL--IPNKSLTTAMQFKLVYKTGDVPLIRIEED 80
           +Q+  YTI EE+     +G L KDL LS+  +P + L  + +              +  +
Sbjct: 28  SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77

Query: 81  TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 139
           +G++   G RIDREK+C    R   C  E E VA  P  +F +V +   I+DINDNAP F
Sbjct: 78  SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130

Query: 140 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 199
            A  I++ I E++    K++L +A D DV  N ++ Y +  +Q  F L   E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189

Query: 200 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
            L+++K LDRE + ++ + +   DGG P  S T  + + VTD NDN PVF +    VS+ 
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249

Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 319
           EN P GTSV ++ ATD D G NA+I ++F N  S I+  LF+LN  TG IT    LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307

Query: 320 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 379
           T  + L V A DGG+  A   V + + D NDN P +      N +       E+  L T 
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361

Query: 380 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAA 439
           IALI V DKD+  NG VTC+T  E+PF+L     N + L  A  L+ E T +Y + ++A 
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421

Query: 440 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNA 499
           D GKP L+    + + + D NDNAPVF Q+   V + ENN PG  + +VSA D D GPN 
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481

Query: 500 KINY-LLGPDAPPE-----FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 553
           +++Y +L  D  P       S+  ++G++   +  D E+   +  T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541

Query: 554 VTVFVSIIDQNDNSPVFTH-------NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVT 606
           V++ V + D NDN+P   +       +     VP        V  +   D D G N+ ++
Sbjct: 542 VSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLS 601

Query: 607 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 664
             +L  ++   F++  +TG +R   +            V   DGG+   S++A + +   
Sbjct: 602 YHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFA 661

Query: 665 D 665
           D
Sbjct: 662 D 662



 Score =  237 bits (604), Expect = 5e-62
 Identities = 192/711 (27%), Positives = 332/711 (46%), Gaps = 57/711 (8%)

Query: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 202
           I  +IPE  A  S+     A D  + +  +   +L + +++ F + +     GD    L+
Sbjct: 31  IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82

Query: 203 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 261
           V   +DRE+     ++  +E     +       + V + D NDN P F    I++ I E+
Sbjct: 83  VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142

Query: 262 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 320
           A  G   +   A DAD+ G + K++    N   +++ +     +   ++ +++PLDRE  
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202

Query: 321 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 378
            +H+L++ A DGG  P      + + VTD NDN P      + +     V L EN+P  T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256

Query: 379 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLL 437
            +  +  TD+D   N  +T  F +  I   L  +  N   + T   LD+E T  Y + + 
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316

Query: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
           A D G    + +    I++ DENDNAP  T    +  IPE++  G  +  +   D DSG 
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374

Query: 498 NAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV 554
           N  +      + P  F L+  +     L +   L+RE+   Y  TI+A D G P L+S  
Sbjct: 375 NGMVTCYTQEEVP--FKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT 432

Query: 555 TVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDEND 614
           ++ + I D NDN+PVF    Y  +V EN P   ++  ++ +DPD G N  V+ SIL  + 
Sbjct: 433 SITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDL 492

Query: 615 D-------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVN 667
           +        ++  Q+GV+    +FD E+  ++   ++A D G  + S++  + + V D+N
Sbjct: 493 EPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLN 552

Query: 668 DNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
           DN P  + P      +  +++V  +  PG +V +V+AVD D+G NA + Y ++  +   L
Sbjct: 553 DNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL 612

Query: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
           F++   TG +         D    R+LV   D GQP    +  +  +F       A  + 
Sbjct: 613 FSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIF-------ADSLQ 665

Query: 784 ELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 834
           E++   ++ P        + S P ++    LV A+A    ++ V+F+ AV+
Sbjct: 666 EVLPDLSDRP--------EPSDPQTELQFYLVVALA----LISVLFLLAVI 704


>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
          Length = 1040

 Score =  348 bits (893), Expect = 1e-95
 Identities = 226/678 (33%), Positives = 353/678 (52%), Gaps = 57/678 (8%)

Query: 27  NYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFT 86
           +YT++EE      +G++ +DL L +    +  +A  F+ V      P + +  +TG ++ 
Sbjct: 21  HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75

Query: 87  TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 146
              +IDRE++C   P    C   +EV +  +    L ++   + DINDN P FP   + +
Sbjct: 76  N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129

Query: 147 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 206
            I E++   +++ L +A DPDVG N +++YE I   + F LDV    +G++  +L+++K 
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188

Query: 207 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 247
           LDRE++  +   +   DGG                     QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248

Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
            F +    VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S  AR LF L+  TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308

Query: 308 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
            + +   LD EE+P +++ V A D G   +PA   VLV V D NDN P I    +   V 
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
                SE     T +AL +VTD+D++ NG+V C    ++PFRL+  F N + + T A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422

Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
            E+   Y + ++A D G+P L+ S  + ++V D NDNAP F+Q    V + ENN PG  +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482

Query: 486 TKVSAMDADSGPNAKINY------LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
             VSA D D G NA++ Y      + G       S++   G L  ++  D E+   + F 
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542

Query: 540 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYNFYVPENLPRHGTVGL---- 591
           + A+D G P  L  N TV + I+DQNDN+P               E LPR    G     
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602

Query: 592 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 647
           +   D D G+N+ +T SI+  +E + F +D +TG +R    +   R+ Q  Y   ++  D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662

Query: 648 GGRVSRSSSAKVTINVVD 665
            G+   SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680



 Score =  234 bits (596), Expect = 4e-61
 Identities = 177/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)

Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
           +++ V D NDN P F E ++ V I E+A  GT      A D D+G N+   +  +     
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162

Query: 295 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 333
                F L+  T         + +++PLDRE+   H+ ++ A DGG              
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221

Query: 334 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 386
             L P +     A++ + V D NDNVP+ D      PV  TV L EN P  T +  +  T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275

Query: 387 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTKEYAIKLLAADAGK 443
           D D   NG V       I  R R +F        LE +  LDYE +  Y + + A D G 
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335

Query: 444 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY 503
             +     + ++V D NDNAP  + S V  ++ E  +PG  +   S  D DS  N ++  
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395

Query: 504 LLGPDAPPEFSLDCRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 562
            L  D P       +     V +  LDRE  D Y  T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455

Query: 563 QNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 615
            NDN+P F+   Y+ YV EN      +  ++ TD D G N+ +  SIL+           
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515

Query: 616 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 674
            +I+S+ G +    SFD E+ + ++F V+A D G     + +A V I +VD NDN P  +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575

Query: 675 VP----PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 730
            P        + E++  S  PG ++ +V AVD D G NA + YSIV GN  +LF +D  T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635

Query: 731 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
           G +    +          + ++++  D GQP    +  +V   V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683



 Score =  182 bits (462), Expect = 1e-45
 Identities = 183/632 (28%), Positives = 270/632 (42%), Gaps = 89/632 (14%)

Query: 252 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 310
           +++  ++ E    GT V  +     D+G +  K+       V N       LN  TG++ 
Sbjct: 18  SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74

Query: 311 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
           + E +DRE+    +P+   H  + L +   L      V + V D+NDN PS        P
Sbjct: 75  VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123

Query: 364 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 413
             D TV +SE+    T+  L +  D D   N       D+EI       FS         
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177

Query: 414 NQFL-LETAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAMLF 453
           N+F  L     LD E    +   L A D                AG PP  Q   +A+L 
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237

Query: 454 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYL----LGPDA 509
           I+V D NDN P F Q   TVS+PEN+ PG  + +++A D D G N ++ Y     + P A
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297

Query: 510 PPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPV 569
              F L  RTG L V  +LD E+   Y   + AKD G   + ++  V V ++D NDN+P 
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357

Query: 570 FTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---VIR 626
            + +     V E       V L +VTD D  +N  V   +L +   F + S       I 
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYTIV 416

Query: 627 PNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVL 686
                DRE  +SYT  V A D G  + S+S  + + V DVNDN P F  P     Y++ +
Sbjct: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPV----YDVYV 472

Query: 687 PSTN-PGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKCD 740
              N PG  ++ V A D D G NA++ YSI+     G +     +I+ E G +  +   D
Sbjct: 473 TENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFD 532

Query: 741 VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI------------NELVRK 788
              L      V+A D G P +L     VN+ + +   NA  I             E++ +
Sbjct: 533 YEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPR 592

Query: 789 STEAPVTPNTEIADVSSPTSDYVKILVAAVAG 820
           S E P    T +A V +   +  ++  + V G
Sbjct: 593 SAE-PGYLLTRVAAVDADDGENARLTYSIVRG 623


>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
          Length = 896

 Score =  348 bits (893), Expect = 1e-95
 Identities = 226/678 (33%), Positives = 353/678 (52%), Gaps = 57/678 (8%)

Query: 27  NYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFT 86
           +YT++EE      +G++ +DL L +    +  +A  F+ V      P + +  +TG ++ 
Sbjct: 21  HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75

Query: 87  TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 146
              +IDRE++C   P    C   +EV +  +    L ++   + DINDN P FP   + +
Sbjct: 76  N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129

Query: 147 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 206
            I E++   +++ L +A DPDVG N +++YE I   + F LDV    +G++  +L+++K 
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188

Query: 207 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 247
           LDRE++  +   +   DGG                     QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248

Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
            F +    VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S  AR LF L+  TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308

Query: 308 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
            + +   LD EE+P +++ V A D G   +PA   VLV V D NDN P I    +   V 
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367

Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
                SE     T +AL +VTD+D++ NG+V C    ++PFRL+  F N + + T A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422

Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
            E+   Y + ++A D G+P L+ S  + ++V D NDNAP F+Q    V + ENN PG  +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482

Query: 486 TKVSAMDADSGPNAKINY------LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
             VSA D D G NA++ Y      + G       S++   G L  ++  D E+   + F 
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542

Query: 540 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYNFYVPENLPRHGTVGL---- 591
           + A+D G P  L  N TV + I+DQNDN+P               E LPR    G     
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602

Query: 592 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 647
           +   D D G+N+ +T SI+  +E + F +D +TG +R    +   R+ Q  Y   ++  D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662

Query: 648 GGRVSRSSSAKVTINVVD 665
            G+   SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680



 Score =  234 bits (596), Expect = 4e-61
 Identities = 177/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)

Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
           +++ V D NDN P F E ++ V I E+A  GT      A D D+G N+   +  +     
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162

Query: 295 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 333
                F L+  T         + +++PLDRE+   H+ ++ A DGG              
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221

Query: 334 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 386
             L P +     A++ + V D NDNVP+ D      PV  TV L EN P  T +  +  T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275

Query: 387 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTKEYAIKLLAADAGK 443
           D D   NG V       I  R R +F        LE +  LDYE +  Y + + A D G 
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335

Query: 444 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY 503
             +     + ++V D NDNAP  + S V  ++ E  +PG  +   S  D DS  N ++  
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395

Query: 504 LLGPDAPPEFSLDCRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 562
            L  D P       +     V +  LDRE  D Y  T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455

Query: 563 QNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 615
            NDN+P F+   Y+ YV EN      +  ++ TD D G N+ +  SIL+           
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515

Query: 616 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 674
            +I+S+ G +    SFD E+ + ++F V+A D G     + +A V I +VD NDN P  +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575

Query: 675 VP----PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 730
            P        + E++  S  PG ++ +V AVD D G NA + YSIV GN  +LF +D  T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635

Query: 731 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
           G +    +          + ++++  D GQP    +  +V   V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683



 Score =  182 bits (462), Expect = 1e-45
 Identities = 183/632 (28%), Positives = 270/632 (42%), Gaps = 89/632 (14%)

Query: 252 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 310
           +++  ++ E    GT V  +     D+G +  K+       V N       LN  TG++ 
Sbjct: 18  SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74

Query: 311 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
           + E +DRE+    +P+   H  + L +   L      V + V D+NDN PS        P
Sbjct: 75  VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123

Query: 364 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 413
             D TV +SE+    T+  L +  D D   N       D+EI       FS         
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177

Query: 414 NQFL-LETAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAMLF 453
           N+F  L     LD E    +   L A D                AG PP  Q   +A+L 
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237

Query: 454 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYL----LGPDA 509
           I+V D NDN P F Q   TVS+PEN+ PG  + +++A D D G N ++ Y     + P A
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297

Query: 510 PPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPV 569
              F L  RTG L V  +LD E+   Y   + AKD G   + ++  V V ++D NDN+P 
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357

Query: 570 FTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---VIR 626
            + +     V E       V L +VTD D  +N  V   +L +   F + S       I 
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYTIV 416

Query: 627 PNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVL 686
                DRE  +SYT  V A D G  + S+S  + + V DVNDN P F  P     Y++ +
Sbjct: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPV----YDVYV 472

Query: 687 PSTN-PGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKCD 740
              N PG  ++ V A D D G NA++ YSI+     G +     +I+ E G +  +   D
Sbjct: 473 TENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFD 532

Query: 741 VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI------------NELVRK 788
              L      V+A D G P +L     VN+ + +   NA  I             E++ +
Sbjct: 533 YEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPR 592

Query: 789 STEAPVTPNTEIADVSSPTSDYVKILVAAVAG 820
           S E P    T +A V +   +  ++  + V G
Sbjct: 593 SAE-PGYLLTRVAAVDADDGENARLTYSIVRG 623


>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
           [Homo sapiens]
          Length = 837

 Score =  346 bits (887), Expect = 7e-95
 Identities = 214/681 (31%), Positives = 352/681 (51%), Gaps = 54/681 (7%)

Query: 12  VLLACVVFHS----GAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
           +LL C+   +     A++  Y++ EE  +   +G++ KDL L   P +     ++   + 
Sbjct: 14  LLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLE--PRELAKRGVR---IV 68

Query: 68  KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 127
             G   L  +   +G + T G RIDRE+LC  +     CF  +E  +L ++  ++  +  
Sbjct: 69  SRGKTQLFAVNPRSGSLITAG-RIDREELCETV---SSCFLNME--LLVEDTLKIYGVEV 122

Query: 128 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 187
            I DINDNAP F    + I + E++   +++ LP A DPDVG+N +Q+Y+L    N F L
Sbjct: 123 EIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQL-SPNNYFSL 181

Query: 188 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 247
            +    +G K P+L+++  LDRE++  +++ +   DGG P R     ++V V D ND+ P
Sbjct: 182 QLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIP 241

Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
           +F ++   VS+PEN   GT V  ++ATD D G N ++ +SF N+ S  A  +F L++ TG
Sbjct: 242 MFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMESK-ASEIFQLDSQTG 300

Query: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367
            + ++  LD E+   +++ +   DGG +     +L+ V DVNDN P I I   +N +   
Sbjct: 301 EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSI--- 357

Query: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYE 427
               EN P  T IAL+ V D+D+  NG+V+CF  + +PF+L   + N + L T+  LD E
Sbjct: 358 ---LENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRE 414

Query: 428 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK 487
             + Y I L A D G PPL+    +++ V D+NDN PVF  S  +  IPENN  G  +  
Sbjct: 415 LVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFS 474

Query: 488 VSAMDADSGPNAKINYLLGPDA------PPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
           V+A+D DS  NA + Y L  D           S++  TG+L  ++  D E+       ++
Sbjct: 475 VTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVI 534

Query: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL---------- 591
           A+D+G PPL+SNV++ + ++DQNDN+P   +          LP  G+ G+          
Sbjct: 535 ARDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 586

Query: 592 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 644
                +   D D G N+ ++  +L  ++   F +   TG +R   +         +  V 
Sbjct: 587 YLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 646

Query: 645 AEDGGRVSRSSSAKVTINVVD 665
            +D G+   S++  +T+ V D
Sbjct: 647 VQDHGQPPLSATVTLTVAVAD 667



 Score =  253 bits (646), Expect = 6e-67
 Identities = 211/725 (29%), Positives = 334/725 (46%), Gaps = 71/725 (9%)

Query: 139 FPATVINISIPENSAINSKYTLPAAVDPDVGIN-------GVQNYELIKSQNIFGLDVIE 191
           F A  I  S+PE +    K +    +  D+G+        GV+     K+Q +F ++   
Sbjct: 27  FRARQIRYSVPEET---EKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQ-LFAVN--- 79

Query: 192 TPEGDKMPQLIVQKELDREEKDTYV------MKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
                +   LI    +DREE    V      M++ VED           ++V + D NDN
Sbjct: 80  ----PRSGSLITAGRIDREELCETVSSCFLNMELLVED-----TLKIYGVEVEIIDINDN 130

Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVSNIARRLFHLNA 304
            P F+E E+E+ + E+A  G      +A D D+G N+   +  S N   ++  R     A
Sbjct: 131 APSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGA 190

Query: 305 TTGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
               + ++  LDRE+   H LL+ A DGG  +      + V V DVND++P         
Sbjct: 191 KNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVY-- 248

Query: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF---SNQFLLE 419
                V + ENI   T++ ++  TD D   NG V  ++   +  +   +F   S    ++
Sbjct: 249 ----RVSVPENISSGTRVLMVNATDPDEGINGEVM-YSFRNMESKASEIFQLDSQTGEVQ 303

Query: 420 TAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 479
               LD+E  + Y +++   D G   L  +  + I V D NDNAP  T +    SI EN+
Sbjct: 304 VRGSLDFEKYRFYEMEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENS 361

Query: 480 SPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKY 536
            PG  +  ++  D DSG N +++  +    P  F L+   G    L   + LDRE    Y
Sbjct: 362 PPGTVIALLNVQDQDSGENGQVSCFIPNHLP--FKLEKTYGNYYKLITSRVLDRELVQSY 419

Query: 537 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTD 596
             T+ A D G PPL++   V++++ D NDN PVF H+ Y+ Y+PEN PR  ++  +T  D
Sbjct: 420 NITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALD 479

Query: 597 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 649
           PD   N+ VT S+ D+       +   +I+S TGV+    SFD E+       V A D G
Sbjct: 480 PDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSG 539

Query: 650 RVSRSSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDT 705
               SS+  +++ V+D NDN P  + P      +   EL   S  PG +V +V+AVD D+
Sbjct: 540 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDS 599

Query: 706 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 765
           G NA + Y ++  +   LFA+ + TG +         D     ++V   D GQP    +V
Sbjct: 600 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 659

Query: 766 VIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 825
            +       +V  A  I E++          N+E +D+S     Y+ + VAAV+    V 
Sbjct: 660 TL-------TVAVADSIPEVLADLGSLESLANSETSDLSL----YLVVAVAAVSCIFLVF 708

Query: 826 VVIFI 830
           V++ +
Sbjct: 709 VIVLL 713


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,552,193
Number of Sequences: 37866
Number of extensions: 1788684
Number of successful extensions: 14301
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 4827
Number of HSP's gapped (non-prelim): 937
length of query: 1025
length of database: 18,247,518
effective HSP length: 112
effective length of query: 913
effective length of database: 14,006,526
effective search space: 12787958238
effective search space used: 12787958238
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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