Guide to the Human Genome
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Search of human proteins with 145580626

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145580626 E2F transcription factor 7 [Homo sapiens]
         (911 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145580626 E2F transcription factor 7 [Homo sapiens]               1794   0.0  
gi|38505226 E2F family member 8 [Homo sapiens]                        390   e-108
gi|4758226 E2F transcription factor 2 [Homo sapiens]                   58   5e-08
gi|12669915 E2F transcription factor 4 [Homo sapiens]                  55   2e-07
gi|4503433 E2F transcription factor 3 [Homo sapiens]                   54   5e-07
gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]       54   5e-07
gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]       54   5e-07
gi|109637795 E2F transcription factor 6 [Homo sapiens]                 54   5e-07
gi|12669911 E2F transcription factor 1 [Homo sapiens]                  50   7e-06
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           48   4e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   5e-05
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    47   1e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         46   1e-04
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              46   2e-04
gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo ...    45   4e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    44   5e-04
gi|119943102 CREB binding protein isoform b [Homo sapiens]             44   7e-04
gi|119943104 CREB binding protein isoform a [Homo sapiens]             44   7e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    43   0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.003
gi|148833494 interferon regulatory factor 5 isoform d [Homo sapi...    42   0.003
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                42   0.003
gi|57863314 vacuolar protein sorting 37C [Homo sapiens]                42   0.003
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             42   0.003
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          40   0.008
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    40   0.008
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    40   0.008
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    40   0.008
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    40   0.008
gi|4504727 interferon regulatory factor 5 isoform a [Homo sapiens]     40   0.010

>gi|145580626 E2F transcription factor 7 [Homo sapiens]
          Length = 911

 Score = 1794 bits (4646), Expect = 0.0
 Identities = 911/911 (100%), Positives = 911/911 (100%)

Query: 1   MEVNCLTLKDLISPRQPRLDFAVEDGENAQKENIFVDRSRMAPKTPIKNEPIDLSKQKKF 60
           MEVNCLTLKDLISPRQPRLDFAVEDGENAQKENIFVDRSRMAPKTPIKNEPIDLSKQKKF
Sbjct: 1   MEVNCLTLKDLISPRQPRLDFAVEDGENAQKENIFVDRSRMAPKTPIKNEPIDLSKQKKF 60

Query: 61  TPERNPITPVKFVDRQQAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKDDAFTD 120
           TPERNPITPVKFVDRQQAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKDDAFTD
Sbjct: 61  TPERNPITPVKFVDRQQAEPWTPTANLKMLISAASPDIRDREKKKGLFRPIENKDDAFTD 120

Query: 121 SLQLDVVGDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLG 180
           SLQLDVVGDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLG
Sbjct: 121 SLQLDVVGDSAVDEFEKQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLG 180

Query: 181 VERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQ 240
           VERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQ
Sbjct: 181 VERRRIYDIVNVLESLHLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQ 240

Query: 241 KELDLIDYKFGERKKDGDPDSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLV 300
           KELDLIDYKFGERKKDGDPDSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLV
Sbjct: 241 KELDLIDYKFGERKKDGDPDSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLV 300

Query: 301 SKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRK 360
           SKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRK
Sbjct: 301 SKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRK 360

Query: 361 PAFKWIGPVDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGSFNTVQASERI 420
           PAFKWIGPVDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGSFNTVQASERI
Sbjct: 361 PAFKWIGPVDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGSFNTVQASERI 420

Query: 421 QRKVNSEPSSPYREEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPV 480
           QRKVNSEPSSPYREEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPV
Sbjct: 421 QRKVNSEPSSPYREEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPV 480

Query: 481 APFPVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPAL 540
           APFPVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPAL
Sbjct: 481 APFPVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPAL 540

Query: 541 LAGQPLVYVPSASLFMLYGSLQEGPASGSGSERDDRSSEAPATVELSSAPSAQKRLCEER 600
           LAGQPLVYVPSASLFMLYGSLQEGPASGSGSERDDRSSEAPATVELSSAPSAQKRLCEER
Sbjct: 541 LAGQPLVYVPSASLFMLYGSLQEGPASGSGSERDDRSSEAPATVELSSAPSAQKRLCEER 600

Query: 601 KPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLP 660
           KPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLP
Sbjct: 601 KPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLP 660

Query: 661 AAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNV 720
           AAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNV
Sbjct: 661 AAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNV 720

Query: 721 LLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGP 780
           LLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGP
Sbjct: 721 LLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGP 780

Query: 781 VNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPES 840
           VNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPES
Sbjct: 781 VNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPES 840

Query: 841 PVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQ 900
           PVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQ
Sbjct: 841 PVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQ 900

Query: 901 RRLEIPSGGAD 911
           RRLEIPSGGAD
Sbjct: 901 RRLEIPSGGAD 911


>gi|38505226 E2F family member 8 [Homo sapiens]
          Length = 867

 Score =  390 bits (1002), Expect = e-108
 Identities = 338/947 (35%), Positives = 458/947 (48%), Gaps = 160/947 (16%)

Query: 30  QKENIFVD-RSRMAPKTPIKNEPIDLSKQKKFTPERNPIT-PVKFVDRQQAEPWTPTANL 87
           +KEN+F +   R   KTP+K          +  P+  P+T P K  +  Q EPWTPTANL
Sbjct: 4   EKENLFCEPHKRGLMKTPLKESTTANIVLAEIQPDFGPLTTPTKPKEGSQGEPWTPTANL 63

Query: 88  KMLISAASPDIRDREKKKGLFRPIENKDDAFTDSLQLDVVGDSAVDEFEKQRPSRKQKSL 147
           KMLISA SP+IR+R++K+GLF       +A  D +   + GD    EFEK +PSRK+KSL
Sbjct: 64  KMLISAVSPEIRNRDQKRGLFDNRSGLPEA-KDCIHEHLSGD----EFEKSQPSRKEKSL 118

Query: 148 GLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVSRVAKNQY 207
           GLLC KFLARYP+YP       I LDEVA  L VERRRIYDIVNVLESLH+VSR+AKN+Y
Sbjct: 119 GLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLHMVSRLAKNRY 178

Query: 208 GWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQKELD-----LIDYKFGE---RKKDGDP 259
            WHGRH+L KTL  L+ +GEE KY EQ+  +++KE +     +  Y   +   +   G  
Sbjct: 179 TWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKKEYEQEFDFIKSYSIEDHIIKSNTGPN 238

Query: 260 DSQEQQLLDFSEPDCPSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILI-EE 318
              +   ++    +  ++S NSRKDKSLR+MSQKFVMLFLVS  +IV+L+VAAKILI E+
Sbjct: 239 GHPDMCFVELPGVEFRAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGED 298

Query: 319 SQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIGP---------- 368
             +  D SKFKTK+RRLYDIANVL+SL LIKKVHVTEERGRKPAFKW GP          
Sbjct: 299 HVEDLDKSKFKTKIRRLYDIANVLSSLDLIKKVHVTEERGRKPAFKWTGPEISPNTSGSS 358

Query: 369 --VDFSSSDEELVDVSASVLPELKRETYGQIQVCAKQKLARHGS-FNTVQASERIQRKVN 425
             + F+ SD E+   S     +    T G      K    RH S    V++ E  +RK+N
Sbjct: 359 PVIHFTPSDLEVRRSSKENCAKNLFSTRG------KPNFTRHPSLIKLVKSIESDRRKIN 412

Query: 426 SEPSSPYR-----EEQGSGGYSLEIGSLAAVYRQKIEDNSQGKAFASKRVVPPSSSLDPV 480
           S PSSP +       Q S  +  ++  LAA+ + ++E+ S       K  +  S    PV
Sbjct: 413 SAPSSPIKTNKAESSQNSAPFPSKMAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPV 472

Query: 481 APF-PVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPA 539
           AP  P ++ + E     L  P+                  G V +  +  +SAV  + P 
Sbjct: 473 APLDPPVNAEMELTAPSLIQPL------------------GMVPLIPSPLSSAVPLILPQ 514

Query: 540 LLAG-------QPL----VYVPSASLFMLYGSLQEGPASGSGSERD--------DRSSEA 580
             +G       QP        P   L     +     A+GS    D        D S  +
Sbjct: 515 APSGPSYAIYLQPTQAHQSVTPPQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKAS 574

Query: 581 PATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPK 640
            +T   S  P+ +++  + R  +   E  +KR S   + G  S    K+     +  S  
Sbjct: 575 ASTRPGSLLPAPERQGAKSRTREPAGERGSKRASMLEDSG--SKKKFKEDLKGLENVSAT 632

Query: 641 TMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENESTKE 700
              +   IPL      G             A S++S                KEN S   
Sbjct: 633 LFPSGYLIPLTQCSSLG-------------AESILS---------------GKENSSALS 664

Query: 701 PSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSV-PCMVLPSP------PL 753
           P+   Y    SP  + G   + S   T       +   PSF V P  ++ SP      P+
Sbjct: 665 PNHRIY---SSP--IAGVIPVTSSELT-------AVNFPSFHVTPLKLMVSPTSVAAVPV 712

Query: 754 GPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIA---QLLVGPTAVVNPKSSTLP 810
           G  P L S + P P+ +     P++  VNF+L  LG I+   QL   P + + P S  + 
Sbjct: 713 GNSPALAS-SHPVPIQN-----PSSAIVNFTLQHLGLISPNVQLSASPGSGIVPVSPRIE 766

Query: 811 SAD--PQ----LQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTPKS 864
           S +  P+     Q + +   SPV  +S     QP      G  V+V    Q PVPVTPK 
Sbjct: 767 SVNVAPENAGTQQGRATNYDSPVPGQS-----QPN-----GQSVAVTGA-QQPVPVTPKG 815

Query: 865 IQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSS------AQRRLEI 905
            Q    E+FF+TPG    P        +  N +S       QR+LE+
Sbjct: 816 SQLV-AESFFRTPGGPTKPTSSSCMDFEGANKTSLGTLFVPQRKLEV 861


>gi|4758226 E2F transcription factor 2 [Homo sapiens]
          Length = 437

 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 39/93 (41%), Positives = 52/93 (55%), Gaps = 8/93 (8%)

Query: 141 SRKQKSLGLLCQKFLARYPSYPLS-TEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLV 199
           +R   SLGLL +KF+     Y LS +E   + L+  A  L V++RRIYDI NVLE + L+
Sbjct: 128 TRYDTSLGLLTKKFI-----YLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLI 182

Query: 200 SRVAKNQYGWHGRHSLPKTLR--NLQRLGEEQK 230
            + AKN   W GR       R    Q+LG+E K
Sbjct: 183 RKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELK 215



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 21/97 (21%)

Query: 272 PDCPSSSAN-SRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKT 330
           P  P S    +R D SL ++++KF+ L   S+  ++ L+ AA++L               
Sbjct: 118 PKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVL-------------DV 164

Query: 331 KVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWIG 367
           + RR+YDI NVL  + LI+K         K   +W+G
Sbjct: 165 QKRRIYDITNVLEGIQLIRK-------KAKNNIQWVG 194


>gi|12669915 E2F transcription factor 4 [Homo sapiens]
          Length = 413

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 6/110 (5%)

Query: 140 PSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLV 199
           PSR +KSLGLL  KF++             ++ D +AV    ++RRIYDI NVLE + L+
Sbjct: 15  PSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVR---QKRRIYDITNVLEGIGLI 71

Query: 200 SRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQKELDLIDYK 249
            + +KN   W G      T     +L E    + ++  LQQ+E +L  +K
Sbjct: 72  EKKSKNSIQWKGVGPGCNTREIADKLIE---LKAEIEELQQREQELDQHK 118



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 22/121 (18%)

Query: 275 PSSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRR 334
           P     SR +KSL +++ KFV L   +K  ++ L +AA  L    +            RR
Sbjct: 10  PPPGTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQK------------RR 57

Query: 335 LYDIANVLTSLALIKKVHVTEERGRKPAFKW--IGP-VDFSSSDEELVDVSASVLPELKR 391
           +YDI NVL  + LI       E+  K + +W  +GP  +     ++L+++ A +    +R
Sbjct: 58  IYDITNVLEGIGLI-------EKKSKNSIQWKGVGPGCNTREIADKLIELKAEIEELQQR 110

Query: 392 E 392
           E
Sbjct: 111 E 111


>gi|4503433 E2F transcription factor 3 [Homo sapiens]
          Length = 465

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 29/71 (40%), Positives = 41/71 (57%), Gaps = 4/71 (5%)

Query: 141 SRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVS 200
           +R   SLGLL +KF+      P       + L++ A  L V++RRIYDI NVLE +HL+ 
Sbjct: 177 TRYDTSLGLLTKKFIQLLSQSP----DGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIK 232

Query: 201 RVAKNQYGWHG 211
           + +KN   W G
Sbjct: 233 KKSKNNVQWMG 243



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 30/83 (36%), Positives = 44/83 (53%), Gaps = 17/83 (20%)

Query: 272 PDCP----SSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSK 327
           PD P    S S  +R D SL ++++KF+ L   S   ++ L+ AA++L            
Sbjct: 164 PDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVL------------ 211

Query: 328 FKTKVRRLYDIANVLTSLALIKK 350
            K + RR+YDI NVL  + LIKK
Sbjct: 212 -KVQKRRIYDITNVLEGIHLIKK 233


>gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]
          Length = 345

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 16/125 (12%)

Query: 141 SRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGV-ERRRIYDIVNVLESLHLV 199
           SR +KSLGLL  KF+    S     +   + L   A +L V ++RRIYDI NVLE + L+
Sbjct: 49  SRHEKSLGLLTTKFV----SLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLI 104

Query: 200 SRVAKNQYGWHGRHSLPKTLRNLQRLG-----------EEQKYEEQMAYLQQKELDLIDY 248
            + +KN   W G  +   T   + RL            +E++ ++Q  +LQQ   +++D 
Sbjct: 105 EKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164

Query: 249 KFGER 253
               R
Sbjct: 165 SINNR 169



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 29/134 (21%)

Query: 251 GERKKDGDPDSQEQQLLDFSEPDCP----SSSANSRKDKSLRIMSQKFVMLFLVSKTKIV 306
           G+R     P +Q  Q      P  P    +   +SR +KSL +++ KFV L   +K  ++
Sbjct: 20  GQRPPPQPPQAQAPQ-----PPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQEAKDGVL 74

Query: 307 TLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWI 366
            L  AA  L    +            RR+YDI NVL  + LI       E+  K + +W 
Sbjct: 75  DLKAAADTLAVRQK------------RRIYDITNVLEGIDLI-------EKKSKNSIQWK 115

Query: 367 GPVDFSSSDEELVD 380
           G V    + +E++D
Sbjct: 116 G-VGAGCNTKEVID 128


>gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]
          Length = 346

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 40/125 (32%), Positives = 62/125 (49%), Gaps = 16/125 (12%)

Query: 141 SRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGV-ERRRIYDIVNVLESLHLV 199
           SR +KSLGLL  KF+    S     +   + L   A +L V ++RRIYDI NVLE + L+
Sbjct: 49  SRHEKSLGLLTTKFV----SLLQEAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLI 104

Query: 200 SRVAKNQYGWHGRHSLPKTLRNLQRLG-----------EEQKYEEQMAYLQQKELDLIDY 248
            + +KN   W G  +   T   + RL            +E++ ++Q  +LQQ   +++D 
Sbjct: 105 EKKSKNSIQWKGVGAGCNTKEVIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDD 164

Query: 249 KFGER 253
               R
Sbjct: 165 SINNR 169



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 29/134 (21%)

Query: 251 GERKKDGDPDSQEQQLLDFSEPDCP----SSSANSRKDKSLRIMSQKFVMLFLVSKTKIV 306
           G+R     P +Q  Q      P  P    +   +SR +KSL +++ KFV L   +K  ++
Sbjct: 20  GQRPPPQPPQAQAPQ-----PPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQEAKDGVL 74

Query: 307 TLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANVLTSLALIKKVHVTEERGRKPAFKWI 366
            L  AA  L    +            RR+YDI NVL  + LI       E+  K + +W 
Sbjct: 75  DLKAAADTLAVRQK------------RRIYDITNVLEGIDLI-------EKKSKNSIQWK 115

Query: 367 GPVDFSSSDEELVD 380
           G V    + +E++D
Sbjct: 116 G-VGAGCNTKEVID 128


>gi|109637795 E2F transcription factor 6 [Homo sapiens]
          Length = 281

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 37/111 (33%), Positives = 58/111 (52%), Gaps = 10/111 (9%)

Query: 137 KQRPSRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESL 196
           K +  R   SL  L +KF+    S P       + L++VA  LGV +RR+YDI NVL+ +
Sbjct: 58  KVKRPRFDVSLVYLTRKFMDLVRSAPGGI----LDLNKVATKLGVRKRRVYDITNVLDGI 113

Query: 197 HLVSRVAKNQYGWHGRHSLPKTLRNLQRLGEEQKYEEQMAYLQQKELDLID 247
            LV + +KN   W G       L N   + +++K +E+++ L   E D +D
Sbjct: 114 DLVEKKSKNHIRWIG-----SDLSNFGAVPQQKKLQEELSDLSAME-DALD 158



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 42/151 (27%), Positives = 63/151 (41%), Gaps = 32/151 (21%)

Query: 282 RKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRLYDIANV 341
           R D SL  +++KF+ L   +   I+ L+  A             +K   + RR+YDI NV
Sbjct: 63  RFDVSLVYLTRKFMDLVRSAPGGILDLNKVA-------------TKLGVRKRRVYDITNV 109

Query: 342 LTSLALIKKVHVTEERGRKPAFKWIGPVDFSS---------SDEELVDVSA--SVLPELK 390
           L  + L+       E+  K   +WIG  D S+           EEL D+SA    L EL 
Sbjct: 110 LDGIDLV-------EKKSKNHIRWIGS-DLSNFGAVPQQKKLQEELSDLSAMEDALDELI 161

Query: 391 RETYGQIQVCAKQKLARHGSFNTVQASERIQ 421
           ++   Q+      K     ++ T Q    IQ
Sbjct: 162 KDCAQQLFELTDDKENERLAYVTYQDIHSIQ 192


>gi|12669911 E2F transcription factor 1 [Homo sapiens]
          Length = 437

 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 33/102 (32%), Positives = 54/102 (52%), Gaps = 8/102 (7%)

Query: 141 SRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVS 200
           SR + SL L  ++FL         +    + L+  A  L V++RRIYDI NVLE + L++
Sbjct: 126 SRYETSLNLTTKRFLELLSH----SADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIA 181

Query: 201 RVAKNQYGWHGRHSLPKTLRNLQRLGEE----QKYEEQMAYL 238
           + +KN   W G H+       L+ L ++    Q+ E+Q+ +L
Sbjct: 182 KKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHL 223



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 13/75 (17%)

Query: 276 SSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSKFKTKVRRL 335
           S    SR + SL + +++F+ L   S   +V L+ AA++L             K + RR+
Sbjct: 121 SPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVL-------------KVQKRRI 167

Query: 336 YDIANVLTSLALIKK 350
           YDI NVL  + LI K
Sbjct: 168 YDITNVLEGIQLIAK 182


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 94/424 (22%), Positives = 156/424 (36%), Gaps = 66/424 (15%)

Query: 513 SMQNGLNGQVD---VSLASAASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEGPASGS 569
           S++ GLN Q     ++  S +S++ SL  A  +G     +PS+S   +  S         
Sbjct: 106 SLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASG-----IPSSSRNAITSSYSSTRGISQ 160

Query: 570 GSERDDRSSE---APATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVM 626
             +R+  SS    +PA+    +     K++ EE               RE +    +   
Sbjct: 161 LWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTT 220

Query: 627 PKKPSDSTDLASPKTMGNR-ASIPLKDIHVNGQ--LPAAEEISGKATANSL-----VSSE 678
           P+K  +S   ++P + G R   + L       Q  LP   ++    TA  L      S +
Sbjct: 221 PRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQ 280

Query: 679 WGNPSRNTDVEKPSK---ENESTKEPSLLQYLCVQSPA---------GLNGFNVLLSGSQ 726
           W N +     +  S    E     +PS    L   +PA           N     L   Q
Sbjct: 281 WFNQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQ 340

Query: 727 TPPTVGP---SSGQLPSFSVPCMVLPS--PPL-----GPFPVLYSPAMPG-PVSSTLGAL 775
           TPP++ P   S+G   + ++     PS  PPL     GP  +L SP+    P ++ LG +
Sbjct: 341 TPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLI 400

Query: 776 PNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQ-------LQSQPSLNLSPVM 828
           P    V    P   + A   +       P++++ PS  P+         + PS   +P  
Sbjct: 401 PAPSMV----PATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAA 456

Query: 829 SRSHSVVQ---------QPESPVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGS 879
           S +  + +         + E P   G  V+      S +P T  +   T +  F     S
Sbjct: 457 SSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVF----SS 512

Query: 880 LGDP 883
           +G P
Sbjct: 513 MGPP 516


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 89/364 (24%), Positives = 124/364 (34%), Gaps = 62/364 (17%)

Query: 551 SASLFMLYGSLQEGPASG--SGSERDDRSSEAPATVELSSAPSAQKRLCEERKPQEEDEP 608
           SA   +  G   E P     S   R D S   P T   + A  ++    E   P+    P
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR----P 192

Query: 609 ATKRQSREYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGK 668
           A   + R   +GP   V       +T+ +        A   L       Q PA+  +S  
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL-------QRPASRSLSSS 245

Query: 669 ATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTP 728
           AT   L S     PS       P+  ++   +                G   L     TP
Sbjct: 246 ATP--LSSPARSGPSARGTPRAPAHPSQPKPK----------------GLQALRPPQVTP 287

Query: 729 PTVGPSSGQLPSFSVPCMVLPSPP---LGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSL 785
           P    +    P  S P +  PSP      P P   + A P P +     LP + P+   L
Sbjct: 288 PRKDAAPALGPLSSSP-LATPSPSGTKARPVPPPDNAATPLPAT-----LPPSPPLATPL 341

Query: 786 PGLGSIAQLLVGPTAVVNPKSSTLPS--ADPQLQSQPSLNLSPVMSRSHSVVQQPESPVY 843
           P        L  P+    P   TLPS  A P  Q+ PS+  +P M    S+   P  P+ 
Sbjct: 342 P--------LAPPSPSAPPSLQTLPSPPATPPSQAPPSMT-TPPMQAPPSLQTIP--PIQ 390

Query: 844 VGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQRRL 903
           V H ++   L   P P+   S+Q T          SLG P L+      + +    Q  L
Sbjct: 391 VPHSLTSPSLQAPPSPLALSSLQAT---------TSLGSPTLQATHSFLTMSPRQTQASL 441

Query: 904 EIPS 907
             PS
Sbjct: 442 TSPS 445



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 84/340 (24%), Positives = 117/340 (34%), Gaps = 39/340 (11%)

Query: 564 GPASGSGSERDDRSSEAPAT-VELSS-APSAQKRLCEE--------RKPQEEDEPATKRQ 613
           GP  G+ S    R S A  T V L   APSA+ R   E               EP+   +
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225

Query: 614 SREYEDGPLSLVMPKKPSDS-TDLASPKTMGNRA-SIPLKDIHVNGQLPAAEEI------ 665
            R    G L     +  S S T L+SP   G  A   P    H +   P   +       
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285

Query: 666 -----SGKATANSLVSSEWGNPSRNTDVEKP--SKENESTKEPSLLQY---------LCV 709
                        L SS    PS +    +P    +N +T  P+ L           L  
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345

Query: 710 QSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVS 769
            SP+       L S   TPP+  P S   P    P  +   PP+     L SP++  P S
Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405

Query: 770 ----STLGALPNTG-PVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNL 824
               S+L A  + G P   +     +++      +     + ++ P   P LQ+  SL  
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465

Query: 825 SPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTPKS 864
           SP +  S S    P S     HP+  +    S  P  P S
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/352 (22%), Positives = 121/352 (34%), Gaps = 30/352 (8%)

Query: 496 PLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLASAASAVESLKPALLAGQPLVYVPSASLF 555
           PL+ P     QT L      + L+  + +    A S++ S  P       ++        
Sbjct: 460 PLSLPASPPLQTSLSP--AVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSS 517

Query: 556 MLYGSLQEGPASGSGSERDDRSSEAPATVELSSAPSAQKRLCEERKPQEEDEPATKRQSR 615
           +   SLQ  PAS +    ++  S AP  ++ +SAP           P  E  P       
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT--------PHLETPPCPAPCPL 569

Query: 616 EYEDGPLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLV 675
           +    PL+   P+ PS S     P+     AS PL+ +      P A     +A     +
Sbjct: 570 QAPPSPLTTPPPETPS-SIATPPPQAPPALASPPLQGLPSPPLSPLATP-PPQAPPXLAL 627

Query: 676 SSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVL-----------LSG 724
                 PS             S + P+ L    +Q+P        +           +S 
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 725 SQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPF---PVLYSPAMPGPVSSTLGALPNTGPV 781
           S TPP+  P S   P   VP     SPP+ P    P    P +  P      + P + P+
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747

Query: 782 NFSLPGLGSIAQLLVGPTAVVNPKSST----LPSADPQLQSQPSLNLSPVMS 829
           + S      +  LL  P   V P         P A P  Q+ P+L   P+ +
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 107/419 (25%), Positives = 144/419 (34%), Gaps = 48/419 (11%)

Query: 470 VVPPSSSLDPVAPFPVLSVDPEYCVNPLAHPVFSVAQTDLQAF-SMQNGLNGQVDVSLAS 528
           + PPS    P AP P L   P     P +    S+    +QA  S+Q     QV  SL S
Sbjct: 343 LAPPS----PSAP-PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 529 AAS-------AVESLKPALLAGQPLVYVPSASLFMLYGSLQEG---PASGSGSERDDRSS 578
            +        A+ SL+     G P +    + L M     Q     P+  + +  D    
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL 457

Query: 579 EAPATVELSSAPSAQKRLCEERKPQEEDEP-----ATKRQSREYEDGPLS-LVMPKKPSD 632
           +AP  + L ++P  Q  L     P           A    +      PLS L+MP   + 
Sbjct: 458 QAP--LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515

Query: 633 STDLASPKTMGNRASIPLKDIHVNGQL--PAAEEISGKATANSLVSSEW-------GNPS 683
           S+ LA P      AS+    +     L  P  +  S   T   L +            PS
Sbjct: 516 SS-LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPS 574

Query: 684 RNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSV 743
             T     +  + +T  P     L      GL   +  LS   TPP   P    LP    
Sbjct: 575 PLTTPPPETPSSIATPPPQAPPALASPPLQGLP--SPPLSPLATPPPQAPPXLALPPLQA 632

Query: 744 PCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVVN 803
           P     SPPL P     SP  P  ++  L   P      FS P    + Q    P A  +
Sbjct: 633 PPSPPASPPLSPLATP-SPQAPNALAVHLLQAP------FSPPPSPPV-QAPFSPPA--S 682

Query: 804 PKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTP 862
           P  S  PSA P  Q+ PSL   P+          P SP     P +   L   P+ V P
Sbjct: 683 PPVS--PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 46/150 (30%), Positives = 59/150 (39%), Gaps = 18/150 (12%)

Query: 722 LSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPV 781
           +S S TPP   P     P   VP     S P+ P       A P   +  L ALP+  P 
Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP-PA 805

Query: 782 NFSLPG---LGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQP 838
           +F  PG       A L + P A   P++  + +A P LQ  PS   SP +       Q P
Sbjct: 806 SF--PGQAPFSPSASLPMSPLATPPPQAPPVLAA-PLLQVPPSPPASPTL-------QAP 855

Query: 839 ESPVYVGHPVSV----VKLHQSPVPVTPKS 864
             P   G   SV    + L  +P P  P S
Sbjct: 856 RRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 94/424 (22%), Positives = 156/424 (36%), Gaps = 66/424 (15%)

Query: 513 SMQNGLNGQVD---VSLASAASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEGPASGS 569
           S++ GLN Q     ++  S +S++ SL  A  +G     +PS+S   +  S         
Sbjct: 106 SLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSG-----IPSSSRNAITSSYSSTRGISQ 160

Query: 570 GSERDDRSSE---APATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVM 626
             +R+  SS    +PA+    +     K++ EE               +E +    +   
Sbjct: 161 LWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADKESQGEKAADTT 220

Query: 627 PKKPSDSTDLASPKTMGNR-ASIPLKDIHVNGQ--LPAAEEISGKATANSL-----VSSE 678
           P+K  +S   ++P + G R   + L       Q  LP   ++    TA  L      S +
Sbjct: 221 PRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQ 280

Query: 679 WGNPSRNTDVEKPSK---ENESTKEPSL---LQYLCVQSP------AGLNGFNVLLSGSQ 726
           W N +     +  S    E   T +PS    L      SP         N     L   Q
Sbjct: 281 WFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQ 340

Query: 727 TPPTVGP---SSGQLPSFSVPCMVLPS--PPL-----GPFPVLYSPAMPG-PVSSTLGAL 775
           TPP++ P   S+G   + ++     PS  PPL     GP  +L SP+    P ++ LG +
Sbjct: 341 TPPSLPPCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLI 400

Query: 776 PNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQ-------LQSQPSLNLSPVM 828
           P    V    P   + A   +       P++++ PS  P+         + PS   +P  
Sbjct: 401 PAPSMV----PATDTKAPPTLQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAA 456

Query: 829 SRSHSVVQ---------QPESPVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPGS 879
           S +  + +         + E P   G  V+      S +P T  +   T +  F     S
Sbjct: 457 SSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVF----SS 512

Query: 880 LGDP 883
           +G P
Sbjct: 513 MGPP 516


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 98/392 (25%), Positives = 147/392 (37%), Gaps = 51/392 (13%)

Query: 471  VPPSSSLDPVAPFPVL--SVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDVSLAS 528
            +P S+ L   A  P L  SV P     PLA  V +       A S  +     + + LA+
Sbjct: 1457 IPISAPLTVSASGPALLTSVTP-----PLAPVVPAAPGPPSLAPSGASPSASALTLGLAT 1511

Query: 529  AASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEG-------PASGSGSERDDRSSEAP 581
            A S   S  P    G PL+  P++S      S           PAS   S      + AP
Sbjct: 1512 APSLSSSQTP----GHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAP 1567

Query: 582  ATVEL-SSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDLASPK 640
            A   L + A SA + L     P    + A    S      PL ++ P  P  +  LAS +
Sbjct: 1568 AQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPS-PGAAPVLASSQ 1626

Query: 641  T---MGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENES 697
            T   +   +S P   +     +PA   +   ++  +++ +   +P     +  P+     
Sbjct: 1627 TPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSP-----LPSPASTQTL 1681

Query: 698  TKEPSLLQYLCVQSPAGLNGFNVLLSGSQTP----PT----VGPSSGQLPSFSVPCMVLP 749
               P+L   L   SP+       L  G+  P    PT    + P+S  +P+ +    + P
Sbjct: 1682 ALAPALAPTLGGSSPS-----QTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP 1736

Query: 750  SPPLGPFPVL-------YSPAMP-GPV-SSTLGALPNTGPVNFSLPGLGSIAQLLVGPTA 800
             PPLGP   L        +PA P GP  + TL   P +   +   P       L   P  
Sbjct: 1737 GPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVP 1796

Query: 801  VVNPKSS-TLPSADPQLQSQPSLNLSPVMSRS 831
             + P ++ TL  A    QS  S   S V+S S
Sbjct: 1797 TLGPAAAQTLALAPASTQSPASQASSLVVSAS 1828



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 107/470 (22%), Positives = 161/470 (34%), Gaps = 84/470 (17%)

Query: 472  PPSSSLDP-VAPFPV-LSVDPEYCVNPLAHP----VFSVAQTDLQAFSMQNGLNGQVDVS 525
            PPS  +   V   P+ L  + E C   LA P    + SVA ++  + S+   +  +  + 
Sbjct: 2531 PPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSL---VPPKDLLP 2587

Query: 526  LASAASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEGPASGSGSERD--DRSSEAPAT 583
            +A     V     +L    P + + + S+    G  QE P S  G+         E P  
Sbjct: 2588 VAVEILPVSEKNLSLTPSAPSLTLEAGSI--PNGQEQEAPDSAEGTTLTVLPEGEELPLC 2645

Query: 584  VELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSD--STDLASPKT 641
            V  S+          +   QE  E    R S E  +       P+KP +  + ++A+P T
Sbjct: 2646 VSESNGLELPPSAASDEPLQEPLE--ADRTSEELTEAKTPTSSPEKPQELVTAEVAAPST 2703

Query: 642  MGNRASIP-------------LKDIHVNGQ------LPAAEEISGKATANSLVSSEWGNP 682
              +  S P               D+ + GQ       P   ++  K     +   E    
Sbjct: 2704 SSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKEL 2763

Query: 683  SRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFS 742
             R     +  +   ST  P + +         +      +SG ++ P +G      PS S
Sbjct: 2764 VRR---RRQQRGAASTLVPGVSETSASPGSPSVRS----MSGPESSPPIGGPCEAAPSSS 2816

Query: 743  VPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVV 802
                 LP+PP  PF               LG      P N      G  A L + P AV 
Sbjct: 2817 -----LPTPPQQPFIARR--------HIELGVTGGGSPEN------GDGALLAITPPAVK 2857

Query: 803  N-----PKSSTLPS-ADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQS 856
                  PK +  P+ A   +   PS  L    +     V  PE+ + V  PV   +L   
Sbjct: 2858 RRRGRPPKKNRSPADAGRGVDEAPSSTLKG-KTNGADPVPGPET-LIVADPVLEPQLIPG 2915

Query: 857  PVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQRRLEIP 906
            P P+ P+ + R         P  L  PV KRR     R      R L IP
Sbjct: 2916 PQPLGPQPVHR---------PNPLLSPVEKRR-----RGRPPKARDLPIP 2951



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 35/114 (30%), Positives = 44/114 (38%), Gaps = 11/114 (9%)

Query: 749  PSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVV---NPK 805
            P  PLGP PV      PGP    L A P  GPV   LP    ++    GP  +     P 
Sbjct: 1015 PRAPLGPVPV---RPPPGP---ELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPG 1068

Query: 806  SSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVP 859
               LP   P   S P +  SP+   S +   +P +P     P     +  SP P
Sbjct: 1069 PVLLPPLQPNSGSLPQVLPSPLGVLSGT--SRPPTPTLSLKPTPPAPVRLSPAP 1120



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 9/101 (8%)

Query: 725  SQTPPTVGPSSGQLP-SFSVPCMV---LPSPPLGPFPVLYSPAMPGPVSSTL-----GAL 775
            S +P     + G  P + S P  V   LP P   P P+  S  +  PVSST+      +L
Sbjct: 1380 SPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSL 1439

Query: 776  PNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQL 816
            P + P     P    +   +  P  V     + L S  P L
Sbjct: 1440 PISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPL 1480



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 38/143 (26%), Positives = 60/143 (41%), Gaps = 25/143 (17%)

Query: 729  PTVGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGL 788
            PT GP    LP+     +++ + P GP P++ +   PGPV      LP   P+    P  
Sbjct: 1036 PTPGPVPQVLPA----SLMVSASPAGP-PLIPASRPPGPV-----LLP---PLQ---PNS 1079

Query: 789  GSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPS----LNLSPVMSRSHSVVQQPES--PV 842
            GS+ Q+L  P  V+   S T     P L  +P+    + LSP      S + +P +  P 
Sbjct: 1080 GSLPQVLPSPLGVL---SGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPG 1136

Query: 843  YVGHPVSVVKLHQSPVPVTPKSI 865
            Y   P +      +    T  ++
Sbjct: 1137 YTFPPAAATTTSTTTATATTTAV 1159



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 35/139 (25%), Positives = 56/139 (40%), Gaps = 5/139 (3%)

Query: 733  PSSGQLPSFSVPCMVLPS-PPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSI 791
            P S   P   +P  +LPS PP    P   SPA   P + T        P    L  +   
Sbjct: 2467 PISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCL--VTPS 2524

Query: 792  AQLLVGPTAV-VNPKSSTLP-SADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVS 849
            + LL+GP +V ++   + LP    P+ +       SP      SV     S + +  P  
Sbjct: 2525 SPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLSLVPPKD 2584

Query: 850  VVKLHQSPVPVTPKSIQRT 868
            ++ +    +PV+ K++  T
Sbjct: 2585 LLPVAVEILPVSEKNLSLT 2603


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 62/260 (23%), Positives = 101/260 (38%), Gaps = 36/260 (13%)

Query: 593  QKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSD-----STDLASPKTMGNRAS 647
            Q +L ++++P    +P +++Q ++ +   + L+M + P       S ++  P+   N  S
Sbjct: 1006 QPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDS 1065

Query: 648  --IPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKE---NESTKEPS 702
              +P++    +G +P    + G A+       +      NT +   S++    ES + PS
Sbjct: 1066 QRMPMQQ---SGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPS 1122

Query: 703  LLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPL---GPFPVL 759
                    SP          SGS+ P   G     +PS     +VLP   L   GP P  
Sbjct: 1123 -------SSPLAEMASLPEASGSEAPSVPG-GPNNMPSH----VVLPQNQLMMTGPKPG- 1169

Query: 760  YSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQ 819
                 P P+S+T GA P   PVN      G     +  PT    PK+    S  P     
Sbjct: 1170 -----PSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQT 1224

Query: 820  PSLNLSPVMSRSHSVVQQPE 839
            P  N  P  +    +   PE
Sbjct: 1225 P--NNRPPSTEPSEISLSPE 1242


>gi|194733742 Wolf-Hirschhorn syndrome candidate 2 protein [Homo
           sapiens]
          Length = 539

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 53/194 (27%), Positives = 68/194 (35%), Gaps = 51/194 (26%)

Query: 688 VEKPSKENESTKEPSLLQY----LCVQSPAGLNGFNVLLSGSQTP--PTVGPSSGQLPSF 741
           VEKP+KE E+  E +   Y    +  Q    LN    L S S  P  P+V P+S  +PS 
Sbjct: 294 VEKPAKE-ETVVENATPDYAAGLVSTQKLGSLNNEPALPSTSYLPSTPSVVPASSYIPSS 352

Query: 742 SVP-------CMVLPSPPLGPFPVL--------------YSPAMPGPVSSTLGALPNTGP 780
             P           P  P  P P L               SPA P P + T    P T P
Sbjct: 353 ETPPAPSSREASRPPEEPSAPSPTLPAQFKQRAPMYNSGLSPATPTPAAPTSPLTPTTPP 412

Query: 781 VNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLS---------PVMSRS 831
                          V PT    P +   P      Q QP  NLS           M ++
Sbjct: 413 A--------------VAPTTQTPPVAMVAPQTQAPAQQQPKKNLSLTREQMFAAQEMFKT 458

Query: 832 HSVVQQPESPVYVG 845
            + V +PE  + +G
Sbjct: 459 ANKVTRPEKALILG 472


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 89/361 (24%), Positives = 118/361 (32%), Gaps = 64/361 (17%)

Query: 564 GPASGSGSERDDRSSEAPAT-VELSS-APSAQKRLCEERKPQEEDEPATKRQSREYEDGP 621
           GP  G+ S    R S A  T V L   APSA+ R      P  E    +   + E+    
Sbjct: 157 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR------PPTEGPRKSVSSASEHSTTE 210

Query: 622 LSLVMPKKPSDSTDLASPKTMG-NRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWG 680
            S    ++PS    L  P +   + ++ PL         PA    S + T  +       
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSS-------PARSGPSARGTPRAPAHPSQP 263

Query: 681 NPS-----RNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNG------FNVLLSGSQTPP 729
            P      R   V  P K+      P     L   SP+             L S   TPP
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323

Query: 730 TVGPSSGQLPSFSVPCMVLPSPPLGP-------------FPVLYSPAMPGPVSSTLGALP 776
           +   +S   P+       LPSPPL P              P L +P  P P S  L  L 
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-PASPPLSPLA 382

Query: 777 NTGP------------VNFSLPGLGSIAQLLVGPTAVVNPKSSTLPS------ADPQLQS 818
              P              FS P    +      P +     S+T PS      A P LQ 
Sbjct: 383 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 442

Query: 819 QPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFKTPG 878
            PS   SP MS S +   Q   P+    P+ + K    P P  P ++     +     P 
Sbjct: 443 PPSPPASPPMSPSATPPPQAPPPL-AAPPLQLAK----PPPQAPPALATPPLQALPSPPA 497

Query: 879 S 879
           S
Sbjct: 498 S 498


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 74/324 (22%), Positives = 127/324 (39%), Gaps = 68/324 (20%)

Query: 619 DGPLSLVMPK-KPSDSTDLASPKTMGN----------RASIPLKDIHVNGQLPAAEEISG 667
           +GPLSL + + + S   +  +P ++GN          RA+ P+     + Q+ +   + G
Sbjct: 667 NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNH---SVQMNSMGSVPG 723

Query: 668 KATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCV-QSPAGLNGFNVLLSGSQ 726
            A + S +         +T+       N   + P+  Q+L   Q P+     +V +   Q
Sbjct: 724 MAISPSRMPQPPNMMGAHTN-------NMMAQAPAQSQFLPQNQFPSSSGAMSVGMG--Q 774

Query: 727 TPPTVGPSSGQLPSFSVP---------CMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPN 777
            P   G S GQ+P  ++P            LP PP+   P+  +P  P   ++ + +L +
Sbjct: 775 PPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPP-PASTAAGMPSLQH 833

Query: 778 TGPVNFSLPGLGSIAQLLVGPTAVVN-------PKSSTLPSADPQLQSQPSLNLSPVMSR 830
           T P   + P   +  Q    P+  V+       P   ++PSA  Q QS P++      + 
Sbjct: 834 TTPPGMTPPQPAAPTQ----PSTPVSSSGQTPTPTPGSVPSA-TQTQSTPTVQ----AAA 884

Query: 831 SHSVVQQPESPVYVGHPVSVVKLHQSPVPV------TPKSIQRTHRETFFKTPGSLGD-- 882
              V  QP++PV      +     Q P PV      TP S      +    TP S+    
Sbjct: 885 QAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAE 944

Query: 883 ----------PVLKRRERNQSRNT 896
                     PVL+ +   Q+ +T
Sbjct: 945 TNSQQPGPDVPVLEMKTETQAEDT 968



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 1/80 (1%)

Query: 742  SVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAV 801
            +VP   LPSP   P P   +     P +    A P   PV+ S  G  S+A+     T  
Sbjct: 1838 NVPQQSLPSPTSAP-PGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS 1896

Query: 802  VNPKSSTLPSADPQLQSQPS 821
                +S +P+  P  Q  P+
Sbjct: 1897 TGKPTSQVPAPPPPAQPPPA 1916


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 74/324 (22%), Positives = 127/324 (39%), Gaps = 68/324 (20%)

Query: 619  DGPLSLVMPK-KPSDSTDLASPKTMGN----------RASIPLKDIHVNGQLPAAEEISG 667
            +GPLSL + + + S   +  +P ++GN          RA+ P+     + Q+ +   + G
Sbjct: 705  NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNH---SVQMNSMGSVPG 761

Query: 668  KATANSLVSSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCV-QSPAGLNGFNVLLSGSQ 726
             A + S +         +T+       N   + P+  Q+L   Q P+     +V +   Q
Sbjct: 762  MAISPSRMPQPPNMMGAHTN-------NMMAQAPAQSQFLPQNQFPSSSGAMSVGMG--Q 812

Query: 727  TPPTVGPSSGQLPSFSVP---------CMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPN 777
             P   G S GQ+P  ++P            LP PP+   P+  +P  P   ++ + +L +
Sbjct: 813  PPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPP-PASTAAGMPSLQH 871

Query: 778  TGPVNFSLPGLGSIAQLLVGPTAVVN-------PKSSTLPSADPQLQSQPSLNLSPVMSR 830
            T P   + P   +  Q    P+  V+       P   ++PSA  Q QS P++      + 
Sbjct: 872  TTPPGMTPPQPAAPTQ----PSTPVSSSGQTPTPTPGSVPSA-TQTQSTPTVQ----AAA 922

Query: 831  SHSVVQQPESPVYVGHPVSVVKLHQSPVPV------TPKSIQRTHRETFFKTPGSLGD-- 882
               V  QP++PV      +     Q P PV      TP S      +    TP S+    
Sbjct: 923  QAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAE 982

Query: 883  ----------PVLKRRERNQSRNT 896
                      PVL+ +   Q+ +T
Sbjct: 983  TNSQQPGPDVPVLEMKTETQAEDT 1006



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 1/80 (1%)

Query: 742  SVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAV 801
            +VP   LPSP   P P   +     P +    A P   PV+ S  G  S+A+     T  
Sbjct: 1876 NVPQQSLPSPTSAP-PGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS 1934

Query: 802  VNPKSSTLPSADPQLQSQPS 821
                +S +P+  P  Q  P+
Sbjct: 1935 TGKPTSQVPAPPPPAQPPPA 1954


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 94/416 (22%), Positives = 144/416 (34%), Gaps = 64/416 (15%)

Query: 526  LASAASAVESLKPALLAGQ-----PLVYVPSASLFMLYGSLQEGPASGSGSERDDRSSEA 580
            +A  A+ +    PA LA +     P + VPS        + +E PA+ S  E     +  
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586

Query: 581  PATVELSSAPSAQKRLCEER----------------KPQEEDEPATKRQSREYEDGPLSL 624
            P+T +   APS ++ L                     P  E  PAT          P   
Sbjct: 1587 PSTYK--GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP--- 1641

Query: 625  VMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSR 684
            V P    DS    +  T    A++P      +  LPA +     A    LV+     P  
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVP----QASKGLPAKK--GPTALKEVLVAPA---PES 1692

Query: 685  NTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVG-------PSSGQ 737
               +  P+++   TK+ S         P+  NG    LS     P +         + G+
Sbjct: 1693 TPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGK 1752

Query: 738  LPSFSVPCMVLPSPPLGPFPVL---YSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQL 794
              S S    + P       P+    +   +P P S+++ A P+  PV  SLP       L
Sbjct: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP-PV--SLP-------L 1802

Query: 795  LVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLH 854
               P   + PK   LPS+   +   PS  L+P       +   P  P+  G P   V ++
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA-DEDELLPLIPPEPISGGVPFQSVLVN 1861

Query: 855  QS-------PVPVTPKSIQRTHRETFFKTPGSLGDPVLKRRERNQSRNTSSAQRRL 903
                     PVP TP + Q   +        S  D  +   E   S   ++ Q +L
Sbjct: 1862 MPTPKSAGIPVP-TPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQL 1916



 Score = 37.7 bits (86), Expect = 0.049
 Identities = 48/175 (27%), Positives = 67/175 (38%), Gaps = 23/175 (13%)

Query: 727  TPPTVGPSSGQLPSFSVPCM----VLPSP---PLGPFPVLYSP--AMPGPVSSTLGALPN 777
            TPP   PS    P+ + P       +PSP   P  P  +  SP  A   PV+    A P+
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429

Query: 778  TGPVN------FSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRS 831
             G +        SL    + +    GP    +    TLP+  P    +P       ++ S
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ--VATS 1487

Query: 832  HSVVQQPESPVYVGHPVSVVKLHQSP--VPVTPKS----IQRTHRETFFKTPGSL 880
             S  + P +P  +G P     +  SP  VP TP S    I  T      KTP +L
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATL 1542



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 106/468 (22%), Positives = 153/468 (32%), Gaps = 66/468 (14%)

Query: 470  VVPPSSSLDPVA-PFPVLSVDPEYCVNPLAHPVFSVAQTDLQ-------AFSMQNGLNGQ 521
            V PPS    P A PFP  +  P     P   P  S A T L        A ++ +   G 
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPP--SPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071

Query: 522  VDVSLASAASAVESLKPALLAG----------QPLVYVPSASLFMLYGSLQEG----PAS 567
               SL  A +   +  P+   G           P    P +    L     +G    PA+
Sbjct: 1072 ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAA 1131

Query: 568  GSGSERDDRSSEAPA---TVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSL 624
               S +   ++  P    T   ++ PS +  L     P  +  P T   +     G L+ 
Sbjct: 1132 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT---PPPKGAPTTPAATPPSPKGGLAT 1188

Query: 625  VMPK---------KPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLV 675
              PK          PS    LA+P   G   +         G L          T  +  
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 676  SSEWGNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLL------------- 722
             S  G P+  T   K +    +   PSL   L      G     V+              
Sbjct: 1249 PSPKGGPA--TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306

Query: 723  SGSQTPPTVGPSSGQLPSFSVPCMVLPSPP-LGPFPVLYSPAMPGPVSSTLGALPNTGPV 781
             G+ TPP   P S +    + P    P+PP + P     +P +P    S+ G    T P 
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG--PTTPS 1364

Query: 782  NFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESP 841
            +   P   +      G  A+  P     P   P + S      SP +    S  + P +P
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPS----PKRGPAIPSPKGDPTSPAVI-PLSPKKAPATP 1419

Query: 842  VYVGHPVSVVKLHQSPVPVTPKSIQRTHRETFFK----TPGSLGDPVL 885
            V      +  K   +P  VTP S+++    +  K    TP S GDP L
Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 57/281 (20%), Positives = 103/281 (36%), Gaps = 25/281 (8%)

Query: 577  SSEAPATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPKKPSDSTDL 636
            +S +P     + AP     L        ++ PAT   SR     P + ++ KK       
Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP-SSRRDPIAPTATLLSKK------- 1537

Query: 637  ASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRNTDVEKPSKENE 696
             +P T+  + ++    I     +P+ ++     T     ++     + +     PS    
Sbjct: 1538 -TPATLAPKEAL----IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592

Query: 697  STKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQL-PSFSVPCMVLPSPPLGP 755
            +     LL    V SP+           + TPP V P S +  P+   P     SPP+ P
Sbjct: 1593 APSPKELLIPPAVTSPSPKE--------APTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 756  FPVLYSPAMPGPVSSTLGA-LPNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADP 814
              +  SP  P  V+  +GA +P       +  G  ++ ++LV P     P  +      P
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704

Query: 815  QLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQ 855
              Q++ S   SP +    S     + P+    P  ++ + +
Sbjct: 1705 --QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK 1743


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 94/378 (24%), Positives = 124/378 (32%), Gaps = 68/378 (17%)

Query: 564 GPASGSGSERDDRSSEAPAT-VELSS-APSAQKRLCEE--------RKPQEEDEPATKRQ 613
           GP  G+ S    R S A  T V L   APSA+ R   E               EP+   +
Sbjct: 166 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225

Query: 614 SREYEDGPLSLVMPKKPSDS-TDLASPKTMGNRA-SIPLKDIHVNGQLPAAEEI------ 665
            R    G L     +  S S T L+SP   G  A   P    H +   P   +       
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285

Query: 666 -----SGKATANSLVSSEWGNPSRNTDVEK------PSKENESTKEPSLLQYLCVQ--SP 712
                        L SS    PS +  ++       P+  + S+    L   L +   SP
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345

Query: 713 AGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCMVLPSPPLGP-------------FPVL 759
           +       L S   TPP+   +S   P+       LPSPPL P              P L
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405

Query: 760 YSPAMPGPVSSTLGALPNTGP------------VNFSLPGLGSIAQLLVGPTAVVNPKSS 807
            +P  P P S  L  L    P              FS P    +      P +     S+
Sbjct: 406 QAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 464

Query: 808 TLPS------ADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVGHPVSVVKLHQSPVPVT 861
           T PS      A P LQ  PS   SP MS S +   Q   P+    P+ + K    P P  
Sbjct: 465 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL-AAPPLQLAK----PPPQA 519

Query: 862 PKSIQRTHRETFFKTPGS 879
           P ++     +     P S
Sbjct: 520 PPALATPPLQALPSPPAS 537


>gi|148833494 interferon regulatory factor 5 isoform d [Homo
           sapiens]
          Length = 514

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 38/135 (28%), Positives = 59/135 (43%), Gaps = 10/135 (7%)

Query: 689 EKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCM-- 746
           E+  +E      PSL     VQS   +  +++L    + PPT+ P + + P+   P +  
Sbjct: 143 EEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVKWPPTLQPPTLRPPTLQPPTLQP 202

Query: 747 --VLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVVNP 804
             VL  P   P P+   P  P      L  +   GP+  SLP  G   QLL  P  +++P
Sbjct: 203 PVVLGPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGE--QLL--PDLLISP 258

Query: 805 KSSTLPSADPQLQSQ 819
               LP  D +++ Q
Sbjct: 259 --HMLPLTDLEIKFQ 271


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/314 (25%), Positives = 110/314 (35%), Gaps = 61/314 (19%)

Query: 566 ASGSGSERDDRSSEAPATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLV 625
           + G  + R   SSE P+T   S  P+A +       P   +  +T      YE    S+V
Sbjct: 133 SEGRNTSRPPTSSEEPST---SVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVV 189

Query: 626 MPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWGNPSRN 685
                  ST +      G   S+PL           A    G +T+    ++E      +
Sbjct: 190 PTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATE----GLS 245

Query: 686 TDVEKPSKENESTKEPSLLQYLCVQS--PAGLNGFNVLL-------SGSQTPPT------ 730
           T V     E  ST  P+        S  PA  +G ++ L       S +  PPT      
Sbjct: 246 TPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLS 305

Query: 731 --VGPSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLP-- 786
             V P++G+  S SVP    P+P  G       P     +S+++   P  GP    LP  
Sbjct: 306 TSVQPTAGEGSSTSVP----PTPG-GGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIP 360

Query: 787 --GL--------------------GSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNL 824
             GL                    G  A  LV PTA   P SS LP+        P    
Sbjct: 361 GEGLSTSVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLPN--------PGEGP 412

Query: 825 SPVMSRSHSVVQQP 838
           S + S S SV + P
Sbjct: 413 STLFSSSASVDRNP 426



 Score = 34.3 bits (77), Expect = 0.54
 Identities = 48/204 (23%), Positives = 74/204 (36%), Gaps = 17/204 (8%)

Query: 626 MPKKPSDSTDLAS------PKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEW 679
           +P+ PSDS  L        P T     S       V   +  A   SG+ T    +S   
Sbjct: 45  VPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPT----ISEGP 100

Query: 680 GNPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLP 739
           G     T  E  S     T    L   + + +  G N      S  +   +V P++ ++P
Sbjct: 101 GTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVP 160

Query: 740 SFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSL--PGLGSIAQLLVG 797
           S S+P    P+P  G    +   A  GP S+++   P+ GP    L  PG G    + + 
Sbjct: 161 STSLP----PTPGEGTSTSVPPTAYEGP-STSVVPTPDEGPSTSVLPTPGEGPGTSVPLA 215

Query: 798 PTAVVNPKSSTLPSADPQLQSQPS 821
            T  ++      P   P     P+
Sbjct: 216 ATEGLSTSVQATPDEGPSTSVPPT 239


>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
          Length = 355

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 45/147 (30%), Positives = 59/147 (40%), Gaps = 14/147 (9%)

Query: 722 LSGSQTPPTVGPSSGQLPSFSVPCMV-LPSPPLG--PFPVLYSPAMPGPVSSTL-GALPN 777
           L+G   PP   P    +P  + P +   P PPL   P+P+ YSP+   PV  T  GALP 
Sbjct: 166 LAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALP- 224

Query: 778 TGPVNFSLPGLGSIAQLLVGPT---AVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSV 834
             P  F +    S     +GPT   A + P+ +   S  PQ    P     P    +   
Sbjct: 225 --PAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPP----RPGYPGTPMG 278

Query: 835 VQQPESPVYVGHPVSVVKLHQSPVPVT 861
              P  P+  G   S     QSP P T
Sbjct: 279 ASGPGYPLRGGRAPSPGYPQQSPYPAT 305


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 69/330 (20%), Positives = 117/330 (35%), Gaps = 22/330 (6%)

Query: 562  QEGPASGSGSERDDRSSEAPAT-VELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDG 620
            + GP S SG         A  T V+L +  SA     +E  P    +  +K  + +  + 
Sbjct: 1575 RSGPPSKSGKRGPFDDQPAGTTGVDLINGSSAHH---QEGVPNGTGQKNSKDSTGKKRED 1631

Query: 621  PLSLVMPKKPSDSTDLASPKTMGNRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEWG 680
            P     PKKP +  D  S   + N AS+ + D H         E++      S ++ +  
Sbjct: 1632 PKP--GPKKPKEKVDALSQFDLNNYASVVIIDDH--------PEVTVIEDPQSNLNDDGF 1681

Query: 681  NPSRNTDVEKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPS 740
                +   +K  ++ E  K+   +  +  +  A   G +     S+ PP           
Sbjct: 1682 TEVVSKKQQKRLQDEERRKKEEQVIQVWNKKNANEKGRS---QTSKLPPRFAKKQATGIQ 1738

Query: 741  FSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTA 800
             +     +P     P P   S ++P   S+ L A     P + S P   S    ++  T+
Sbjct: 1739 QAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTS 1798

Query: 801  VVNPKSSTLP---SADPQLQSQPSLNLSPVMSRSHSVVQQPESPVY--VGHPVSVVKLHQ 855
               P S   P   SA        S + + + S S        +P+   V  P SV  L  
Sbjct: 1799 APVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVTILAS 1858

Query: 856  SPVPVTPKSIQRTHRETFFKTPGSLGDPVL 885
            + +P+   ++  T   T      S   PV+
Sbjct: 1859 ASIPILASALASTSAPTPAPAASSPAAPVI 1888


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 83/364 (22%), Positives = 122/364 (33%), Gaps = 53/364 (14%)

Query: 468  KRVVPP---SSSLDPVAPFPVLSVDPEYCVNPLAHPVFSVAQTDLQAFSMQNGLNGQVDV 524
            K   PP   S++   VAP    S         L  PV S   + + +F   +   G+   
Sbjct: 1382 KHTEPPVTSSATTTSVAPPAATSTSSTAVFGSL--PVTSAGSSGVISFGGTSLSAGKTSF 1439

Query: 525  SLASA---ASAVESLKPALLAGQPLVYVPSASLFMLYGSLQEG------PASGSGSERDD 575
            S  S    ++   S  P   A  PL   P++   + +GSL         P S   S  + 
Sbjct: 1440 SFGSQQTNSTVPPSAPPPTTAATPL---PTSFPTLSFGSLLSSATTPSLPMSAGRSTEEA 1496

Query: 576  RSSEAPATVELSSAPSAQKRLCEERKPQEEDEPATKRQSREYEDGPLSLVMPK-----KP 630
             SS  P     S   ++   L EE+  Q    P    Q+ +       L  P        
Sbjct: 1497 TSSALPEKPGDSEVSASAASLLEEQ--QSAQLPQAPPQTSDSVKKEPVLAQPAVSNSGTA 1554

Query: 631  SDSTDL------ASPKTMG-----NRASIPLKDIHVNGQLPAAEEISGKATANSLVSSEW 679
            + ST L      A+P T G       A  P     V GQ          A   ++ +S  
Sbjct: 1555 ASSTSLVALSAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSST 1614

Query: 680  GNPSRNTDVEKPSKENESTKEPSLLQYLCV--QSPAGLNG--FNVLLSGSQTPPTVGPSS 735
               S  T +  P    E+    ++     V  Q PA  +   FN L + + T P+  P  
Sbjct: 1615 PIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSATPVF 1674

Query: 736  GQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLL 795
            GQ+ + + P +                   G  +ST  A P      FS P  G+ A  +
Sbjct: 1675 GQVAASTAPSLF--------------GQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGV 1720

Query: 796  VGPT 799
             G T
Sbjct: 1721 FGQT 1724



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 44/159 (27%), Positives = 60/159 (37%), Gaps = 29/159 (18%)

Query: 714 GLNGFNVLLSGSQTPPTVGPSSGQLPSF--------------------SVPCMVLPS-PP 752
           G +GF   L  +  P    P+    PSF                    S P     S PP
Sbjct: 549 GSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPP 608

Query: 753 LGPFPVLYSPAMPGPVS--STLGALPNTGPVNFS-LPG-LGSIAQLLVGPTAVVNPKSS- 807
           + PF     PA  GP+S  + L A P++ P+  S LP   G  AQ    P   +  KS  
Sbjct: 609 MSPFSSASKPAASGPLSHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPSMVQKSPR 668

Query: 808 -TLPSADPQLQSQPSLNLSPVMSRSHSVVQQPESPVYVG 845
            T P+A P   S  + +L P ++       +   PV  G
Sbjct: 669 ITPPAAKP--GSPQAKSLQPAVAEKQGHQWKDSDPVMAG 705


>gi|55953110 retinoblastoma protein-binding zinc finger protein
           isoform c [Homo sapiens]
          Length = 1481

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 51/182 (28%), Positives = 59/182 (32%), Gaps = 31/182 (17%)

Query: 681 NPSRNTDVEKPSKENESTKEPSL-------------LQYLCVQSPAGLNGFNVLLSGSQT 727
           NP+  T    P K  E+  +P L                +C  SPA        LS  Q 
Sbjct: 704 NPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPS---LSSGQL 760

Query: 728 PPTVGPSSGQLPSFSVPC-----MVLPSPPL---GPFPVLYSPAMPGPVSSTLGALPNTG 779
           PP + P+    PS   PC     +  P PPL    P P   S A P P  S L       
Sbjct: 761 PPLLIPTD---PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQS 817

Query: 780 PVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPE 839
           P    LP L         P   V P  S      P L S  S + S     S S    P 
Sbjct: 818 P----LPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPS 873

Query: 840 SP 841
            P
Sbjct: 874 PP 875


>gi|20336260 retinoblastoma protein-binding zinc finger protein
            isoform b [Homo sapiens]
          Length = 1682

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 51/182 (28%), Positives = 59/182 (32%), Gaps = 31/182 (17%)

Query: 681  NPSRNTDVEKPSKENESTKEPSL-------------LQYLCVQSPAGLNGFNVLLSGSQT 727
            NP+  T    P K  E+  +P L                +C  SPA        LS  Q 
Sbjct: 905  NPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPS---LSSGQL 961

Query: 728  PPTVGPSSGQLPSFSVPC-----MVLPSPPL---GPFPVLYSPAMPGPVSSTLGALPNTG 779
            PP + P+    PS   PC     +  P PPL    P P   S A P P  S L       
Sbjct: 962  PPLLIPTD---PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQS 1018

Query: 780  PVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPE 839
            P    LP L         P   V P  S      P L S  S + S     S S    P 
Sbjct: 1019 P----LPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPS 1074

Query: 840  SP 841
             P
Sbjct: 1075 PP 1076


>gi|20336258 retinoblastoma protein-binding zinc finger protein
            isoform a [Homo sapiens]
          Length = 1718

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 51/182 (28%), Positives = 59/182 (32%), Gaps = 31/182 (17%)

Query: 681  NPSRNTDVEKPSKENESTKEPSL-------------LQYLCVQSPAGLNGFNVLLSGSQT 727
            NP+  T    P K  E+  +P L                +C  SPA        LS  Q 
Sbjct: 905  NPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPS---LSSGQL 961

Query: 728  PPTVGPSSGQLPSFSVPC-----MVLPSPPL---GPFPVLYSPAMPGPVSSTLGALPNTG 779
            PP + P+    PS   PC     +  P PPL    P P   S A P P  S L       
Sbjct: 962  PPLLIPTD---PSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQS 1018

Query: 780  PVNFSLPGLGSIAQLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSVVQQPE 839
            P    LP L         P   V P  S      P L S  S + S     S S    P 
Sbjct: 1019 P----LPILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPS 1074

Query: 840  SP 841
             P
Sbjct: 1075 PP 1076


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 40/136 (29%), Positives = 48/136 (35%), Gaps = 15/136 (11%)

Query: 733 PSSGQLPSFSVPCMVLPSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIA 792
           P S + P  SVP  V+ S P    P    PA   PV+   G  P       S      I 
Sbjct: 708 PLSAEGPHLSVPASVIVSAP----PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI- 762

Query: 793 QLLVGPTAVVNPKSSTLPSADPQLQSQPSLNLSPVMSRSHSV---VQQPESPVYVGHPVS 849
                P A   P     PS+ P L  Q  L  SP +   H      + P  P  V  P S
Sbjct: 763 -----PAAA--PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815

Query: 850 VVKLHQSPVPVTPKSI 865
              LH  P P  P ++
Sbjct: 816 EPPLHPCPPPQAPPTL 831


>gi|4504727 interferon regulatory factor 5 isoform a [Homo sapiens]
          Length = 504

 Score = 40.0 bits (92), Expect = 0.010
 Identities = 38/131 (29%), Positives = 57/131 (43%), Gaps = 12/131 (9%)

Query: 689 EKPSKENESTKEPSLLQYLCVQSPAGLNGFNVLLSGSQTPPTVGPSSGQLPSFSVPCMVL 748
           E+  +E      PSL     VQS   +  +++L    + PPT+ P + Q      P +VL
Sbjct: 143 EEEEEEELQRMLPSLSLTDAVQSGPHMTPYSLLKEDVKWPPTLQPPTLQ------PPVVL 196

Query: 749 PSPPLGPFPVLYSPAMPGPVSSTLGALPNTGPVNFSLPGLGSIAQLLVGPTAVVNPKSST 808
             P   P P+   P  P      L  +   GP+  SLP  G   QLL  P  +++P    
Sbjct: 197 GPPAPDPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGE--QLL--PDLLISP--HM 250

Query: 809 LPSADPQLQSQ 819
           LP  D +++ Q
Sbjct: 251 LPLTDLEIKFQ 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,810,168
Number of Sequences: 37866
Number of extensions: 2023945
Number of successful extensions: 7773
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 356
Number of HSP's that attempted gapping in prelim test: 6954
Number of HSP's gapped (non-prelim): 1126
length of query: 911
length of database: 18,247,518
effective HSP length: 111
effective length of query: 800
effective length of database: 14,044,392
effective search space: 11235513600
effective search space used: 11235513600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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