Guide to the Human Genome
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Search of human proteins with 144226234

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|144226234 metastasis suppressor 1 [Homo sapiens]
         (755 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|144226234 metastasis suppressor 1 [Homo sapiens]                  1514   0.0  
gi|46195763 metastasis suppressor 1-like [Homo sapiens]               770   0.0  
gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]        70   7e-12
gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]          70   7e-12
gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens]          70   7e-12
gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens]          70   7e-12
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]            57   6e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        56   1e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    56   1e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    53   1e-06
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    52   2e-06
gi|221139926 NHS-like 1 [Homo sapiens]                                 52   2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   49   1e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   49   1e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   49   1e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    49   1e-05
gi|55750053 atrophin-1 [Homo sapiens]                                  49   1e-05
gi|55750041 atrophin-1 [Homo sapiens]                                  49   1e-05
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             49   2e-05
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    49   2e-05
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    49   2e-05
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    49   2e-05
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    49   2e-05
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    49   2e-05
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        49   2e-05
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        49   2e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   2e-05
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    47   5e-05
gi|50345997 E1A binding protein p300 [Homo sapiens]                    47   7e-05

>gi|144226234 metastasis suppressor 1 [Homo sapiens]
          Length = 755

 Score = 1514 bits (3920), Expect = 0.0
 Identities = 755/755 (100%), Positives = 755/755 (100%)

Query: 1   MEAVIEKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQK 60
           MEAVIEKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQK
Sbjct: 1   MEAVIEKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQK 60

Query: 61  VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVAN 120
           VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVAN
Sbjct: 61  VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVAN 120

Query: 121 QLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQDVNDKYLLLEETE 180
           QLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQDVNDKYLLLEETE
Sbjct: 121 QLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQDVNDKYLLLEETE 180

Query: 181 KQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDLKSLTMDPHKLPSSS 240
           KQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDLKSLTMDPHKLPSSS
Sbjct: 181 KQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDLKSLTMDPHKLPSSS 240

Query: 241 EQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYR 300
           EQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYR
Sbjct: 241 EQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYR 300

Query: 301 YRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESH 360
           YRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESH
Sbjct: 301 YRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESH 360

Query: 361 VGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQ 420
           VGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQ
Sbjct: 361 VGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQ 420

Query: 421 PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480
           PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA
Sbjct: 421 PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480

Query: 481 LALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQ 540
           LALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQ
Sbjct: 481 LALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQ 540

Query: 541 EFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR 600
           EFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR
Sbjct: 541 EFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR 600

Query: 601 RGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM 660
           RGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM
Sbjct: 601 RGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM 660

Query: 661 PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADL 720
           PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADL
Sbjct: 661 PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADL 720

Query: 721 SPRDTPQGEDMLNAIRRGVKLKKTTTNDRSAPRFS 755
           SPRDTPQGEDMLNAIRRGVKLKKTTTNDRSAPRFS
Sbjct: 721 SPRDTPQGEDMLNAIRRGVKLKKTTTNDRSAPRFS 755


>gi|46195763 metastasis suppressor 1-like [Homo sapiens]
          Length = 747

 Score =  770 bits (1988), Expect = 0.0
 Identities = 438/786 (55%), Positives = 529/786 (67%), Gaps = 83/786 (10%)

Query: 6   EKECSALGGLFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMA 65
           EKEC ALGGLFQ I++DMK SYP+WEDF +KA KL SQLRTTV+AA AFLDAFQKVADMA
Sbjct: 5   EKECGALGGLFQAIVNDMKSSYPIWEDFNSKATKLHSQLRTTVLAAVAFLDAFQKVADMA 64

Query: 66  TNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKD 125
           TNTRG TR+IGSALTRMCMRHRSIE KLRQF++AL++ LINPLQE++E+WKK ANQLDKD
Sbjct: 65  TNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINPLQERIEDWKKAANQLDKD 124

Query: 126 HAKEYKKARQEIKKKSSDTLKLQKKAKK---GRGDIQPQLDSALQDVNDKYLLLEETEKQ 182
           HAKEYK+AR EIKKKSSDTLKLQKKA+K   G+GD+QPQLDSALQDVND YLLLEETEKQ
Sbjct: 125 HAKEYKRARHEIKKKSSDTLKLQKKARKELLGKGDLQPQLDSALQDVNDMYLLLEETEKQ 184

Query: 183 AVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDLKSLTMDPHKLPSSSEQ 242
           AVR+ALIEERGRFCTFI+ L+PV+  E++MLGEITHLQ I +DL  LT +PHKLP +SEQ
Sbjct: 185 AVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDLVVLTAEPHKLPPASEQ 244

Query: 243 VILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSS----GSHSHSPSSH 298
           VI DLKGSDYSWSYQTPPSSPS++ SRKSS+CS+ +S +S+    +    G+ ++SPSS 
Sbjct: 245 VIKDLKGSDYSWSYQTPPSSPSSSSSRKSSMCSAPSSSSSAKGGGAPWPGGAQTYSPSST 304

Query: 299 YRYRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSE 358
            RYRS         RLSSVSSHDSGF+SQDA  SK PSPMP +  +Q S+     S SSE
Sbjct: 305 CRYRSLAQPATTTARLSSVSSHDSGFVSQDATYSKPPSPMPSDITSQKSSS----SASSE 360

Query: 359 SHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPY 418
                           AS     V+    P                      DW+K G +
Sbjct: 361 ----------------ASETCQSVSECSSPT--------------------SDWSKVGSH 384

Query: 419 DQPLVNTLQRRKEK------REPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEE 472
           +QP   TLQRRK++       EP P  GG    SG     EEA RPR    + A + GEE
Sbjct: 385 EQPSGATLQRRKDRVELLRDTEPGPASGGTLGPSG-----EEAPRPRMSPATIAAKHGEE 439

Query: 473 ME-ACEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSV 531
           +  A  +LA+ L+RGL L+ Q+SSRDSLQ SSGYSTQTTTP CSEDTIPSQ SDYD +SV
Sbjct: 440 VSPAASDLAMVLTRGLSLEHQKSSRDSLQYSSGYSTQTTTPSCSEDTIPSQGSDYDCYSV 499

Query: 532 SGDQEAD-QQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPT------TLGPAMVTP 584
           +GD +++   EFDKSSTIPRNS+I+Q+YRR+ Q KRPASTAGLPT      T  P+   P
Sbjct: 500 NGDADSEGPPEFDKSSTIPRNSNIAQNYRRLIQTKRPASTAGLPTAGLPTATGLPSGAPP 559

Query: 585 GVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEE----- 639
           GVATIRRTPSTKP+VRR    AGPIPI+ P++PVKTPTVPD PG +     G EE     
Sbjct: 560 GVATIRRTPSTKPTVRRALSSAGPIPIRPPIVPVKTPTVPDSPGYMGPTRAGSEECVFYT 619

Query: 640 RGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGP------------KPSIPEEHR 687
               SP +P + +      S+P++ W   +      PG             + S+ E+  
Sbjct: 620 DETASPLAPDLAKASPKRLSLPNTAWGSPSPEAAGYPGAGAEDEQQQLAANRHSLVEKLG 679

Query: 688 QAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRDTPQGEDMLNAIRRGVKLKKTTTN 747
           + +  + A  + + P    +S     E+     +    P  EDML AIRRGV+L++T TN
Sbjct: 680 ELVAGAHALGEGQFPFPTALSATPTEETPTPPPAATSDPPAEDMLVAIRRGVRLRRTVTN 739

Query: 748 DRSAPR 753
           DRSAPR
Sbjct: 740 DRSAPR 745


>gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]
          Length = 534

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 83/379 (21%), Positives = 164/379 (43%), Gaps = 35/379 (9%)

Query: 15  LFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTRE 74
           +++TI+       P   +FI      +  L     AA  + DA  K+ ++A+ ++G ++E
Sbjct: 16  VYKTIMEQFN---PSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQG-SKE 71

Query: 75  IGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKAR 134
           +G  L +M   HR I+ +L +   +  + L+  L++++E   +  +   K +  E +   
Sbjct: 72  LGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKG 131

Query: 135 QEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQ---DVNDKYLLLEETEKQAVRKALIEE 191
             + K  ++  KL+KK+ +G  + Q   D  LQ    +++K   LE       + AL EE
Sbjct: 132 DALDKCQAELKKLRKKS-QGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEE 190

Query: 192 RGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL-KSLTMDPHKLPSSSEQVILDLKGS 250
           R RFC  +     V +   +   +   L      L +    DP K+P  + Q++  +   
Sbjct: 191 RRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQV--- 247

Query: 251 DYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQA 310
                        S   +  S++ +S +++  SD          P     +     AQ++
Sbjct: 248 ------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQES 295

Query: 311 PVRLSSVSSHD----SGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGA 366
              ++ V+  D    S +  + A Q KS S  PP++ ++LS+ +S+ +L     V P  +
Sbjct: 296 TPIMNGVTGPDGEDYSPWADRKAAQPKSLS--PPQSQSKLSDSYSN-TLPVRKSVTPKNS 352

Query: 367 GLFPHCLPASRLLPRVTSV 385
               +    ++ LPR +S+
Sbjct: 353 ----YATTENKTLPRSSSM 367


>gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]
          Length = 520

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 83/379 (21%), Positives = 164/379 (43%), Gaps = 35/379 (9%)

Query: 15  LFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTRE 74
           +++TI+       P   +FI      +  L     AA  + DA  K+ ++A+ ++G ++E
Sbjct: 16  VYKTIMEQFN---PSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQG-SKE 71

Query: 75  IGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKAR 134
           +G  L +M   HR I+ +L +   +  + L+  L++++E   +  +   K +  E +   
Sbjct: 72  LGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKG 131

Query: 135 QEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQ---DVNDKYLLLEETEKQAVRKALIEE 191
             + K  ++  KL+KK+ +G  + Q   D  LQ    +++K   LE       + AL EE
Sbjct: 132 DALDKCQAELKKLRKKS-QGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEE 190

Query: 192 RGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL-KSLTMDPHKLPSSSEQVILDLKGS 250
           R RFC  +     V +   +   +   L      L +    DP K+P  + Q++  +   
Sbjct: 191 RRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQV--- 247

Query: 251 DYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQA 310
                        S   +  S++ +S +++  SD          P     +     AQ++
Sbjct: 248 ------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQES 295

Query: 311 PVRLSSVSSHD----SGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGA 366
              ++ V+  D    S +  + A Q KS S  PP++ ++LS+ +S+ +L     V P  +
Sbjct: 296 TPIMNGVTGPDGEDYSPWADRKAAQPKSLS--PPQSQSKLSDSYSN-TLPVRKSVTPKNS 352

Query: 367 GLFPHCLPASRLLPRVTSV 385
               +    ++ LPR +S+
Sbjct: 353 ----YATTENKTLPRSSSM 367


>gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens]
          Length = 521

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 83/379 (21%), Positives = 164/379 (43%), Gaps = 35/379 (9%)

Query: 15  LFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTRE 74
           +++TI+       P   +FI      +  L     AA  + DA  K+ ++A+ ++G ++E
Sbjct: 16  VYKTIMEQFN---PSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQG-SKE 71

Query: 75  IGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKAR 134
           +G  L +M   HR I+ +L +   +  + L+  L++++E   +  +   K +  E +   
Sbjct: 72  LGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKG 131

Query: 135 QEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQ---DVNDKYLLLEETEKQAVRKALIEE 191
             + K  ++  KL+KK+ +G  + Q   D  LQ    +++K   LE       + AL EE
Sbjct: 132 DALDKCQAELKKLRKKS-QGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEE 190

Query: 192 RGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL-KSLTMDPHKLPSSSEQVILDLKGS 250
           R RFC  +     V +   +   +   L      L +    DP K+P  + Q++  +   
Sbjct: 191 RRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQV--- 247

Query: 251 DYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQA 310
                        S   +  S++ +S +++  SD          P     +     AQ++
Sbjct: 248 ------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQES 295

Query: 311 PVRLSSVSSHD----SGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGA 366
              ++ V+  D    S +  + A Q KS S  PP++ ++LS+ +S+ +L     V P  +
Sbjct: 296 TPIMNGVTGPDGEDYSPWADRKAAQPKSLS--PPQSQSKLSDSYSN-TLPVRKSVTPKNS 352

Query: 367 GLFPHCLPASRLLPRVTSV 385
               +    ++ LPR +S+
Sbjct: 353 ----YATTENKTLPRSSSM 367


>gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens]
          Length = 552

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 83/379 (21%), Positives = 164/379 (43%), Gaps = 35/379 (9%)

Query: 15  LFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTRE 74
           +++TI+       P   +FI      +  L     AA  + DA  K+ ++A+ ++G ++E
Sbjct: 16  VYKTIMEQFN---PSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQG-SKE 71

Query: 75  IGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKAR 134
           +G  L +M   HR I+ +L +   +  + L+  L++++E   +  +   K +  E +   
Sbjct: 72  LGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKG 131

Query: 135 QEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQ---DVNDKYLLLEETEKQAVRKALIEE 191
             + K  ++  KL+KK+ +G  + Q   D  LQ    +++K   LE       + AL EE
Sbjct: 132 DALDKCQAELKKLRKKS-QGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEE 190

Query: 192 RGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL-KSLTMDPHKLPSSSEQVILDLKGS 250
           R RFC  +     V +   +   +   L      L +    DP K+P  + Q++  +   
Sbjct: 191 RRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQV--- 247

Query: 251 DYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQA 310
                        S   +  S++ +S +++  SD          P     +     AQ++
Sbjct: 248 ------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQES 295

Query: 311 PVRLSSVSSHD----SGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGA 366
              ++ V+  D    S +  + A Q KS S  PP++ ++LS+ +S+ +L     V P  +
Sbjct: 296 TPIMNGVTGPDGEDYSPWADRKAAQPKSLS--PPQSQSKLSDSYSN-TLPVRKSVTPKNS 352

Query: 367 GLFPHCLPASRLLPRVTSV 385
               +    ++ LPR +S+
Sbjct: 353 ----YATTENKTLPRSSSM 367


>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
          Length = 511

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 57/290 (19%), Positives = 122/290 (42%), Gaps = 28/290 (9%)

Query: 28  PVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTREIGSALTRMCMRHR 87
           P   + IN     +  +   ++A  A+ D   K+ ++AT +   T E+G  L  +   H+
Sbjct: 25  PGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVST-ELGHVLIEISSTHK 83

Query: 88  SIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKL 147
            +   L +        +I+ L++++E   K  N   K +  E+K   + ++K  ++  K+
Sbjct: 84  KLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKI 143

Query: 148 QKKAKKGRGDIQPQLDSA--LQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPV 205
           ++K++  R  ++ +      ++ V  +   +++      ++AL+EE+ RFC        +
Sbjct: 144 RRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCF-------L 196

Query: 206 IEEEISMLGEITHLQTISEDL--------KSLTMDPHKLPSSSEQVILDLKGSDYSWSYQ 257
           +++       I +    S +L        +   +D  K+P     +I ++K         
Sbjct: 197 VDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIK--------- 247

Query: 258 TPPSSPSTTMSRKSSVCSSLNSVNSS-DSRSSGSHSHSPSSHYRYRSSNL 306
           TP S+P +   + S +    N V    D+ S  S    P+   R  +S L
Sbjct: 248 TPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPL 297



 Score = 34.7 bits (78), Expect = 0.34
 Identities = 40/143 (27%), Positives = 55/143 (38%), Gaps = 33/143 (23%)

Query: 637 PEER-----GEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSI--------- 682
           PEE+     GEH   S + G  P   T +     +   +V  P P P  SI         
Sbjct: 372 PEEKDGWLYGEHDV-SKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENS 430

Query: 683 -----PEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRDTP--------QGE 729
                P ++ + +    A D+ R   + T S  + P S P   +P D           GE
Sbjct: 431 SVVIPPPDYLECLSMGAAADR-RADSARTTSTFKAPASKPETAAPNDANGTAKPPFLSGE 489

Query: 730 DMLNAIRRGVKLKKTTTNDRSAP 752
           +        VKL+ T TNDRSAP
Sbjct: 490 NPFAT----VKLRPTVTNDRSAP 508


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 123/546 (22%), Positives = 188/546 (34%), Gaps = 89/546 (16%)

Query: 212  MLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKS 271
            +LGE T     +  + S +M+   LP S+    L    S+ S ++ + P SP+TT+S  S
Sbjct: 934  LLGEST-----TSPISSGSMETTALPGSTTTPGL----SERSTTFHSSPRSPATTLSPAS 984

Query: 272  SVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFI------ 325
            +  S + S  S+ SRS    +H+ +      +  L++ +    SS  S D+  +      
Sbjct: 985  TTSSGV-SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 1043

Query: 326  ---SQDAFQSKSPS-----PMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASR 377
               SQ++  S S S      + P +   LS  F   S +  S+ G T   LFP    +S 
Sbjct: 1044 SGPSQESTTSHSSSGSTDTALSPGSTTALS--FGQESTTFHSNPGSTHTTLFPDSTTSSG 1101

Query: 378  LLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDP 437
            ++   T VH    +   T+ P    S           PG   +              P P
Sbjct: 1102 IVEASTRVHSSTGSPRTTLSPASSTS-----------PGLQGESTAFQTHPASTHTTPSP 1150

Query: 438  NGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRD 497
                P+TA+ P   +    R      S  + P     A               T   S  
Sbjct: 1151 ----PSTATAPVEESTTYHR------SPGSTPTTHFPASS------------TTSGHSEK 1188

Query: 498  SLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQS 557
            S    S      TTP  +  T   +          G  E        S+T P  S+ S +
Sbjct: 1189 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI--TTLPGSTTTPGLSEASTT 1246

Query: 558  YRRMFQAKRPASTAGLPTTLGPAMVTP-GVATIRRTPSTKPSVRRGTIGAGPIPIKTPVI 616
            +         +S     TTL PA +T  GV     T  ++P     T+   P    TP +
Sbjct: 1247 FY--------SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV--SPASTTTPGL 1296

Query: 617  PVKTPTVPD----------LPGVLPAPPDGPEERGEHS-PESP-----SVGEGPQGVTSM 660
              ++ TV             P        G E    HS P S      +      G+T  
Sbjct: 1297 SEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 1356

Query: 661  PSSMWSGQASVNPPLPGPKPSIP-EEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
             ++     AS    LP    +    E     P S      +  P+ + + G + ES P+ 
Sbjct: 1357 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR 1416

Query: 720  LSPRDT 725
            LSP  T
Sbjct: 1417 LSPSST 1422



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 124/544 (22%), Positives = 186/544 (34%), Gaps = 85/544 (15%)

Query: 212  MLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKS 271
            +LGE T     +  + S +M+   LP S+    L    S+ S ++ + P SP+TT+S  S
Sbjct: 2017 LLGEST-----TSPISSGSMETTALPGSTTTPGL----SEKSTTFHSSPRSPATTLSPAS 2067

Query: 272  SVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFI------ 325
            +  S + S  S+ S S    +H+ +      +  L++ +    SS  S D+  +      
Sbjct: 2068 TTSSGV-SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 2126

Query: 326  SQDAFQSKSPSPMPPEAPNQLSNG------FSHYSLSSESHVGPTGAGLFPHCLPASRLL 379
            S  + +S +    P      LS G      F   S +  S  G T   LFP    +S ++
Sbjct: 2127 SGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIV 2186

Query: 380  PRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNG 439
               T VH    +   T+ P    S           PG   +              P P  
Sbjct: 2187 EASTRVHSSTGSPRTTLSPASSTS-----------PGLQGESTAFQTHPASTHTTPSP-- 2233

Query: 440  GGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSL 499
              P+TA+ P   +    R      S  + P     A               T   S  S 
Sbjct: 2234 --PSTATAPVEESTTYHR------SPGSTPTTHFPASS------------TTSGHSEKST 2273

Query: 500  QCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYR 559
               S      TTP  +  T   +          G  E        S+T P  S+ S ++ 
Sbjct: 2274 IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI--TTLPGSTTTPGLSEASTTFY 2331

Query: 560  RMFQAKRPASTAGLPTTLGPAMVTP-GVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPV 618
                    +S     TTL PA +T  GV     T  ++P     T+   P    TP +  
Sbjct: 2332 --------SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV--SPASTTTPGLSE 2381

Query: 619  KTPTV-PDLPG-----VLPAPPD----GPEERGEHS-PESP-----SVGEGPQGVTSMPS 662
            ++ TV    PG     V P  P     G E    HS P S      +      G+T   +
Sbjct: 2382 ESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 2441

Query: 663  SMWSGQASVNPPLPGPKPSIP-EEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLS 721
            +     AS    LP    +    E     P S         P+ + + G + ES P+ LS
Sbjct: 2442 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLS 2501

Query: 722  PRDT 725
            P  T
Sbjct: 2502 PSST 2505



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 123/547 (22%), Positives = 189/547 (34%), Gaps = 91/547 (16%)

Query: 212  MLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKS 271
            +LGE T     +  + S +M+   LP S+    L    S+ S ++ + P SP+TT+S  S
Sbjct: 3574 LLGEST-----TSPISSGSMETTALPGSTTTPGL----SEKSTTFHSSPRSPATTLSPAS 3624

Query: 272  SVCSSLNSVN-SSDSRSSGSHS--------------HSPSSHYRYRSSNLAQQAPVRLSS 316
            +  S ++  + +S SR   +H+              HS +SH    S++         +S
Sbjct: 3625 TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 3684

Query: 317  VSSHDSGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPAS 376
             SS +S   +  +    + + + P +   LS  F   S +  S  G T   LFP    +S
Sbjct: 3685 GSSQES--TTSHSSSGSTDTALSPGSTTALS--FGQESTTFHSSPGSTHTTLFPDSTTSS 3740

Query: 377  RLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPD 436
             ++   T VH    +   T+ P    S           PG   +              P 
Sbjct: 3741 GIVEASTRVHSSTGSPRTTLSPASSTS-----------PGLQGESTAFQTHPASTHTTPS 3789

Query: 437  PNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSR 496
            P    P+TA+ P   +    R      S  + P     A               T   S 
Sbjct: 3790 P----PSTATAPVEESTTYHR------SPGSTPTTHFPASS------------TTSGHSE 3827

Query: 497  DSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQ 556
             S    S      TTP  +  T   +          G  E        S+T P  S+ S 
Sbjct: 3828 KSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI--TTLPGSTTTPGLSEAST 3885

Query: 557  SYRRMFQAKRPASTAGLPTTLGPAMVTP-GVATIRRTPSTKPSVRRGTIGAGPIPIKTPV 615
            ++         +S     TTL PA +T  GV     T  ++P     T+   P    TP 
Sbjct: 3886 TFY--------SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV--SPASTTTPG 3935

Query: 616  IPVKTPTV-PDLPG-----VLPAPPDGPEERGE----HS-PESP-----SVGEGPQGVTS 659
            +  ++ TV    PG     V P        R E    HS P S      +      G+T 
Sbjct: 3936 LSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTE 3995

Query: 660  MPSSMWSGQASVNPPLPGPKPSIP-EEHRQAIPESEAEDQEREPPSATVSPGQIPESDPA 718
              ++     AS    LP    +    E     P S      +  P+ + + G + ES P+
Sbjct: 3996 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS 4055

Query: 719  DLSPRDT 725
             LSP  T
Sbjct: 4056 RLSPSST 4062



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 119/516 (23%), Positives = 181/516 (35%), Gaps = 96/516 (18%)

Query: 250  SDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQ 309
            S+ S ++ T P SP  T+S  ++  S + S  SS S S    +H+ +      +  L++ 
Sbjct: 2520 SEKSTTFYTSPRSPDATLSPATTTSSGV-SEESSTSHSQPGSTHTTAFPDSTTTPGLSRH 2578

Query: 310  APVRLSSVSSHDSGFI------SQDAFQSKSPSPMPPEAPNQLSNG------FSHYSLSS 357
            +    SS  S D+  +      S  + +S +    P      LS G      F   S + 
Sbjct: 2579 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTF 2638

Query: 358  ESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGP 417
             S  G T   LFP    +S ++   T VH    +   T+ P    SS  P  +       
Sbjct: 2639 HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA---SSTSPGLQ------- 2688

Query: 418  YDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACE 477
                                  G  TT    PA+      P     S AT P EE     
Sbjct: 2689 ----------------------GESTTFQTHPASTHTTPSP----PSTATAPVEESTTYH 2722

Query: 478  ELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSED---TIPSQVSDYDYFSVSGD 534
                  S G    T  +   +   +SG+S ++T    S D   T PS      + + SG 
Sbjct: 2723 R-----SPG---STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA----HSTTSGR 2770

Query: 535  QEADQQEFDKSS----TIPRNS---DISQSYRRMFQAKRPASTAGLPTTLGPAMVTP-GV 586
             E+        S    T+P ++    +S++    + + R  +     TTL PA +T  GV
Sbjct: 2771 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPT-----TTLSPASMTSLGV 2825

Query: 587  ATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTV-PDLPG-----VLPAPPD----G 636
                 T  ++P     T+   P    TP +  ++ TV    PG     V P        G
Sbjct: 2826 GEESTTSRSQPGSTHSTV--SPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRG 2883

Query: 637  PEERGEHS-PESP-----SVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIP-EEHRQA 689
             E    HS P S      +      G+T   ++     AS    LP    +    E    
Sbjct: 2884 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 2943

Query: 690  IPESEAEDQEREPPSATVSPGQIPESDPADLSPRDT 725
             P S         P+ + + G + ES P+ LSP  T
Sbjct: 2944 FPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSST 2979



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 119/573 (20%), Positives = 192/573 (33%), Gaps = 76/573 (13%)

Query: 234  HKLPSSSEQVIL--DLKGSDYSWSYQTPPSSPSTTMSRKSSVCSS--LNSVNSSDSRSSG 289
            H  P+S+   +   D   S  +      P SP++T +   +  ++  L   +++   SSG
Sbjct: 2890 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 2949

Query: 290  SHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDS---GFISQDAFQSKSP----SPMPPEA 342
            S   + S      S  + +  P RLS  S+  +   G  +  +   KS     SP  P+A
Sbjct: 2950 STGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 3009

Query: 343  P----NQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGP 398
                    S+G S  S +S S  G T    FP     S L    T+ H    +   T+ P
Sbjct: 3010 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSP 3069

Query: 399  GMFPSSQI--PSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQ 456
            G   +S +   S    + PG  +  L+           PD         +  P  +    
Sbjct: 3070 GSTTASSLGQQSTTFHSSPGDTETTLL-----------PDDTITSGLVEASTPTHSSTGS 3118

Query: 457  RPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGY-----STQTTT 511
               ++T +++T  G + E+    +   S         ++   ++ S+ Y     ST TT 
Sbjct: 3119 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 3178

Query: 512  PCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI----PRNSDISQSYRRMFQAKRP 567
               S  T+          S  G           ++++    P  S IS            
Sbjct: 3179 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 3238

Query: 568  ASTAGL--------------PTTLGPAMVT-PGVATIRRTPSTKPSVRRGTIGAG----P 608
             +TAGL               TTL PA  T  GV+    T  ++P     T   G    P
Sbjct: 3239 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 3298

Query: 609  IPIKTPVIPVKTPTVPDL---PGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMP-SSM 664
               +       +P   D    PG   A   GPE    HS      G G    T +P ++ 
Sbjct: 3299 GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS------GPGSTETTLLPDNTT 3352

Query: 665  WSGQASVNPPLP----------GPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPE 714
             SG    + P+            P  S   +      +S    ++  P   T +   +  
Sbjct: 3353 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 3412

Query: 715  SDPADLSPRDTPQGEDMLNAIRRGVKLKKTTTN 747
            S  +  SP  TP      ++   G   + TT +
Sbjct: 3413 STTSHGSPSSTPTTHFSASSTTLGRSEESTTVH 3445



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 121/571 (21%), Positives = 191/571 (33%), Gaps = 72/571 (12%)

Query: 234  HKLPSSSEQVIL--DLKGSDYSWSYQTPPSSPSTTMSRKSSVCSS--LNSVNSSDSRSSG 289
            H  P+S+   +   D   S  +      P SP++T +   +  ++  L   +++   SSG
Sbjct: 3973 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 4032

Query: 290  SHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDS---GFISQDAFQSKSP----SPMPPEA 342
            S     S      S  + +  P RLS  S+  +   G  +  +   KS     SP  P+A
Sbjct: 4033 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 4092

Query: 343  P----NQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGP 398
                    S+G S  S +S S  G T    FP     S L    T+ H    +   T+ P
Sbjct: 4093 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSP 4152

Query: 399  GMFPSSQI--PSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQ 456
            G   +S +   S    + PG  +  L+           PD         +  P  +    
Sbjct: 4153 GSTTASSLGQQSTTFHSSPGDTETTLL-----------PDDTITSGLVEASTPTHSSTGS 4201

Query: 457  RPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGY-----STQTTT 511
               ++T +++T  G + E+    +   S         ++   ++ S+ Y     ST TT 
Sbjct: 4202 LHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTH 4261

Query: 512  PCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI----PRNSDISQSYRRMFQAKRP 567
               S  T+          S  G           ++++    P  S IS            
Sbjct: 4262 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 4321

Query: 568  ASTAGL--------------PTTLGPAMVT-PGVATIRRTPSTKPSVRRGTIGAGPIPIK 612
             +TAGL               TTL PA  T  GV+    T  ++P     T  A P    
Sbjct: 4322 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTT--AFPSSTT 4379

Query: 613  TPVI----------PVKTPTVPDLPGVLPAPPDGPEERGEH-SPESPSVGEGP-----QG 656
             P +          P  T T    PG   A   GPE    H SP S      P      G
Sbjct: 4380 MPGVSQESTASHSSPGSTDTTLS-PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG 4438

Query: 657  VTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESD 716
            +    + + S   S +  L  P  S   +      +S    ++  P   T +   +  S 
Sbjct: 4439 LLEASTPVHSSTGSPHTTL-SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELST 4497

Query: 717  PADLSPRDTPQGEDMLNAIRRGVKLKKTTTN 747
             +  SP  TP      ++   G   + TT +
Sbjct: 4498 TSHGSPSSTPTTHFSASSTTLGRSEESTTVH 4528



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 119/568 (20%), Positives = 190/568 (33%), Gaps = 66/568 (11%)

Query: 234  HKLPSSSEQVIL--DLKGSDYSWSYQTPPSSPSTTMSRKSSVCSS--LNSVNSSDSRSSG 289
            H  P+S+   +   D   S  +      P SP++T +   +  ++  L   +++   SSG
Sbjct: 1333 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 1392

Query: 290  SHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDS---GFISQDAFQSKSP----SPMPPEA 342
            S     S      S  + +  P RLS  S+  +   G  +  +   KS     SP  P+A
Sbjct: 1393 STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 1452

Query: 343  P----NQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGP 398
                    S+G S  S +S S  G T    FP     S L    T+ H    +   T+ P
Sbjct: 1453 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSP 1512

Query: 399  GMFPSSQI--PSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQ 456
            G   +S +   S    + PG  +  L+           PD         +  P  +    
Sbjct: 1513 GSTTASSLGQQSTTFHSSPGDTETTLL-----------PDDTITSGLVEASTPTHSSTGS 1561

Query: 457  RPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGY-----STQTTT 511
               ++T +++T  G + E+    +   S         ++   ++ S+ Y     ST TT 
Sbjct: 1562 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1621

Query: 512  PCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI----PRNSDISQSYRRMFQAKRP 567
               S  T+          S  G           ++++    P  S IS            
Sbjct: 1622 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 1681

Query: 568  ASTAGL--------------PTTLGPAMVT-PGVATIRRTPSTKPSVRRGTIGAG----P 608
             +TAGL               TTL PA  T  GV+    T  ++P     T   G    P
Sbjct: 1682 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 1741

Query: 609  IPIKTPVIPVKTPTVPDL---PGVLPAPPDGPEERGEH-SPESPSVGEGP-----QGVTS 659
               +       +P   D    PG   A   GPE    H SP S      P      G+  
Sbjct: 1742 GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLE 1801

Query: 660  MPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
              + + S   S +  L  P  S   +      +S    ++  P   T +   +  S  + 
Sbjct: 1802 ASTPVHSSTGSPHTTL-SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH 1860

Query: 720  LSPRDTPQGEDMLNAIRRGVKLKKTTTN 747
             SP  TP      ++   G   + TT +
Sbjct: 1861 GSPSSTPTTHFSASSTTLGRSEESTTVH 1888



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 124/540 (22%), Positives = 188/540 (34%), Gaps = 92/540 (17%)

Query: 250 SDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSH----------SHSPSSHY 299
           SDY  S      S +T    K  + SS NS +S +S  S S           SHS +S +
Sbjct: 193 SDYGVSVTFITGSTAT----KHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVF 248

Query: 300 --RYRSSNLAQQAPVRLSSVSSHDSGFISQDA--FQSKSPSPMPPEAPNQL-SNGFSHYS 354
               ++S +   +    +   S  +  +S+ +  F S   SP    +P +  S+G S  S
Sbjct: 249 VGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKS 308

Query: 355 LSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAK 414
            +S S  GPT    FP       +    T+ H    +   T+ PG    S +        
Sbjct: 309 TTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL-------- 360

Query: 415 PGPYDQPLVNTLQRRKEKREPD-PNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGE-- 471
            GP      ++    K  R PD     G   AS P  ++  +        S+ T  GE  
Sbjct: 361 -GPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPT 419

Query: 472 -------EMEACEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVS 524
                    +     +   S  ++L T   S  S   ++ +S  +TT   SE++ P   S
Sbjct: 420 TFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSS 479

Query: 525 DY--------DYFSVSGDQE-----------ADQQEFDKSSTIPRNSDISQSYR---RMF 562
                        + SG  E                F +SST   +S+ S ++       
Sbjct: 480 PVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT 539

Query: 563 QAKRPASTAGLPTTLGPAMVTPGVATIRRTPST--KPSVRRGTIGAGPIPIKTPVIPV-K 619
           ++  P++TA L  T   + +     T  R  ST    S       + P  + T V+P   
Sbjct: 540 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGS 599

Query: 620 TPTV-----------------PDLPGVLPAPPDGPEERGE---HSPESPSVGEGPQGVTS 659
           TP+V                   LPG    P  G  E+      SP SP     P    S
Sbjct: 600 TPSVLVGDSTPSPISSGSMETTALPGSTTKP--GLSEKSTTFYSSPRSPDTTHLP---AS 654

Query: 660 MPSSMWSGQASVNPPLPGPKPSIPEEHRQAIP----ESEAEDQEREPPSATVSPGQIPES 715
           M SS  S +++ +   PG   +        +P    ES A      P   T+SPG    S
Sbjct: 655 MTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTAS 714



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 119/539 (22%), Positives = 178/539 (33%), Gaps = 78/539 (14%)

Query: 255  SYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRL 314
            SY +   S  TT  R SS  S  +  + +   S  + + +        S  +    P  +
Sbjct: 554  SYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPI 613

Query: 315  SSVSSHDS---GFISQDAFQSKSP----SPMPPEAPN----QLSNGFSHYSLSSESHVGP 363
            SS S   +   G  ++     KS     SP  P+  +      S+G S  S +S S  G 
Sbjct: 614  SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGS 673

Query: 364  TGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQI-PSWKDW-AKPGPYDQP 421
            T    FP       L    T+ H        T+ PG   +S + P +  + ++PG  +  
Sbjct: 674  THTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETT 733

Query: 422  LVNTLQRRKEKREPD-PNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480
            L+           PD     G   AS P  ++  +         + TR GE        +
Sbjct: 734  LL-----------PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPS 782

Query: 481  LALSRGLQLDTQRSSRDSLQCSSGY-STQTTTPCCSEDTIPSQVSDYDYF--SVSGDQEA 537
               +R     T  +  +    S G  S+  TT   +  T    V +   +  S    Q  
Sbjct: 783  SKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 842

Query: 538  DQQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGL--------------PTTLGPAMVT 583
               E D +S     S  S S      +  P++T+ L               TT  P   T
Sbjct: 843  HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 902

Query: 584  PGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVP---------DLPGVLPAPP 634
                +   T S       GTI   P    T V+  ++ T P          LPG    P 
Sbjct: 903  TSGRSEESTASHSSQDATGTI-VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP- 960

Query: 635  DGPEERG---EHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIP 691
             G  ER      SP SP+    P   T   SS  S +++ +   PG        H  A P
Sbjct: 961  -GLSERSTTFHSSPRSPATTLSPASTT---SSGVSEESTTSRSRPG------STHTTAFP 1010

Query: 692  ESEAEDQEREPPSATVSPGQIPESDPADLSPRDTPQGEDMLNAIRRGVKLKKTTTNDRS 750
            +S            T +PG    S  +  SP  T       +    G   + TT++  S
Sbjct: 1011 DS------------TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSS 1057


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 123/546 (22%), Positives = 188/546 (34%), Gaps = 89/546 (16%)

Query: 212 MLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKS 271
           +LGE T     +  + S +M+   LP S+    L    S+ S ++ + P SP+TT+S  S
Sbjct: 421 LLGEST-----TSPISSGSMETTALPGSTTTPGL----SERSTTFHSSPRSPATTLSPAS 471

Query: 272 SVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFI------ 325
           +  S + S  S+ SRS    +H+ +      +  L++ +    SS  S D+  +      
Sbjct: 472 TTSSGV-SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 530

Query: 326 ---SQDAFQSKSPS-----PMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASR 377
              SQ++  S S S      + P +   LS  F   S +  S+ G T   LFP    +S 
Sbjct: 531 SGPSQESTTSHSSSGSTDTALSPGSTTALS--FGQESTTFHSNPGSTHTTLFPDSTTSSG 588

Query: 378 LLPRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDP 437
           ++   T VH    +   T+ P    S           PG   +              P P
Sbjct: 589 IVEASTRVHSSTGSPRTTLSPASSTS-----------PGLQGESTAFQTHPASTHTTPSP 637

Query: 438 NGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRD 497
               P+TA+ P   +    R      S  + P     A               T   S  
Sbjct: 638 ----PSTATAPVEESTTYHR------SPGSTPTTHFPASS------------TTSGHSEK 675

Query: 498 SLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQS 557
           S    S      TTP  +  T   +          G  E        S+T P  S+ S +
Sbjct: 676 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI--TTLPGSTTTPGLSEASTT 733

Query: 558 YRRMFQAKRPASTAGLPTTLGPAMVTP-GVATIRRTPSTKPSVRRGTIGAGPIPIKTPVI 616
           +         +S     TTL PA +T  GV     T  ++P     T+   P    TP +
Sbjct: 734 FY--------SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV--SPASTTTPGL 783

Query: 617 PVKTPTVPD----------LPGVLPAPPDGPEERGEHS-PESP-----SVGEGPQGVTSM 660
             ++ TV             P        G E    HS P S      +      G+T  
Sbjct: 784 SEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 843

Query: 661 PSSMWSGQASVNPPLPGPKPSIP-EEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
            ++     AS    LP    +    E     P S      +  P+ + + G + ES P+ 
Sbjct: 844 STAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR 903

Query: 720 LSPRDT 725
           LSP  T
Sbjct: 904 LSPSST 909



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 119/568 (20%), Positives = 190/568 (33%), Gaps = 66/568 (11%)

Query: 234  HKLPSSSEQVIL--DLKGSDYSWSYQTPPSSPSTTMSRKSSVCSS--LNSVNSSDSRSSG 289
            H  P+S+   +   D   S  +      P SP++T +   +  ++  L   +++   SSG
Sbjct: 820  HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSG 879

Query: 290  SHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDS---GFISQDAFQSKSP----SPMPPEA 342
            S     S      S  + +  P RLS  S+  +   G  +  +   KS     SP  P+A
Sbjct: 880  STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 939

Query: 343  P----NQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGP 398
                    S+G S  S +S S  G T    FP     S L    T+ H    +   T+ P
Sbjct: 940  TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSP 999

Query: 399  GMFPSSQI--PSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQ 456
            G   +S +   S    + PG  +  L+           PD         +  P  +    
Sbjct: 1000 GSTTASSLGQQSTTFHSSPGDTETTLL-----------PDDTITSGLVEASTPTHSSTGS 1048

Query: 457  RPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGY-----STQTTT 511
               ++T +++T  G + E+    +   S         ++   ++ S+ Y     ST TT 
Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1108

Query: 512  PCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI----PRNSDISQSYRRMFQAKRP 567
               S  T+          S  G           ++++    P  S IS            
Sbjct: 1109 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 1168

Query: 568  ASTAGL--------------PTTLGPAMVT-PGVATIRRTPSTKPSVRRGTIGAG----P 608
             +TAGL               TTL PA  T  GV+    T  ++P     T   G    P
Sbjct: 1169 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 1228

Query: 609  IPIKTPVIPVKTPTVPDL---PGVLPAPPDGPEERGEH-SPESPSVGEGP-----QGVTS 659
               +       +P   D    PG   A   GPE    H SP S      P      G+  
Sbjct: 1229 GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLE 1288

Query: 660  MPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
              + + S   S +  L  P  S   +      +S    ++  P   T +   +  S  + 
Sbjct: 1289 ASTPVHSSTGSPHTTL-SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSH 1347

Query: 720  LSPRDTPQGEDMLNAIRRGVKLKKTTTN 747
             SP  TP      ++   G   + TT +
Sbjct: 1348 GSPSSTPTTHFSASSTTLGRSEESTTVH 1375



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 119/539 (22%), Positives = 178/539 (33%), Gaps = 78/539 (14%)

Query: 255 SYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRL 314
           SY +   S  TT  R SS  S  +  + +   S  + + +        S  +    P  +
Sbjct: 41  SYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPI 100

Query: 315 SSVSSHDS---GFISQDAFQSKSP----SPMPPEAPN----QLSNGFSHYSLSSESHVGP 363
           SS S   +   G  ++     KS     SP  P+  +      S+G S  S +S S  G 
Sbjct: 101 SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGS 160

Query: 364 TGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIGPGMFPSSQI-PSWKDW-AKPGPYDQP 421
           T    FP       L    T+ H        T+ PG   +S + P +  + ++PG  +  
Sbjct: 161 THTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETT 220

Query: 422 LVNTLQRRKEKREPD-PNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480
           L+           PD     G   AS P  ++  +         + TR GE        +
Sbjct: 221 LL-----------PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPS 269

Query: 481 LALSRGLQLDTQRSSRDSLQCSSGY-STQTTTPCCSEDTIPSQVSDYDYF--SVSGDQEA 537
              +R     T  +  +    S G  S+  TT   +  T    V +   +  S    Q  
Sbjct: 270 SKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 329

Query: 538 DQQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGL--------------PTTLGPAMVT 583
              E D +S     S  S S      +  P++T+ L               TT  P   T
Sbjct: 330 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 389

Query: 584 PGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVP---------DLPGVLPAPP 634
               +   T S       GTI   P    T V+  ++ T P          LPG    P 
Sbjct: 390 TSGRSEESTASHSSQDATGTI-VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP- 447

Query: 635 DGPEERG---EHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIP 691
            G  ER      SP SP+    P   T   SS  S +++ +   PG        H  A P
Sbjct: 448 -GLSERSTTFHSSPRSPATTLSPASTT---SSGVSEESTTSRSRPG------STHTTAFP 497

Query: 692 ESEAEDQEREPPSATVSPGQIPESDPADLSPRDTPQGEDMLNAIRRGVKLKKTTTNDRS 750
           +S            T +PG    S  +  SP  T       +    G   + TT++  S
Sbjct: 498 DS------------TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSS 544


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 76/318 (23%), Positives = 109/318 (34%), Gaps = 31/318 (9%)

Query: 429 RKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQ 488
           R++   P P    P  A    AA  E   PR    + + RP    E   +   + S    
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP---APSARPRPPTEGPRKSVSSASEHST 208

Query: 489 LDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEAD---QQEFDKS 545
            +   ++R       G     +    S  T P         S  G   A     Q   K 
Sbjct: 209 TEPSPAARRRPSAGGGLQRPASRSLSSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKG 267

Query: 546 STIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPA----MVTPGVATIRRTPSTKPSVRR 601
               R   ++   +    A  P S++ L T    A       P + T+   P+T PS   
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327

Query: 602 GTIGAGPIPI------KTPVIPVKTPTVPDLPGVLPAPP-DGPEERGEHSPESPSVGEGP 654
            ++G+  +          P+ P+ TP  P  P  L  PP   P       P SP     P
Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPP-PQAPPALALPPLQAPPSPPASPPLSPLATPSP 386

Query: 655 QGVTSMPSSMWSGQAS--VNPPLPGP--KPSIPEEHRQAIPESEAEDQEREPPSATVSPG 710
           Q   ++   +     S   +PP+  P   P+ P     A P S+A      PPS    P 
Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA------PPSLAAPPL 440

Query: 711 QIPESDPAD--LSPRDTP 726
           Q+P S PA   +SP  TP
Sbjct: 441 QVPPSPPASPPMSPSATP 458



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 78/330 (23%), Positives = 111/330 (33%), Gaps = 66/330 (20%)

Query: 441 GPTTASGPPAAAEEAQRPRSMT-----------VSAATRPGE------EMEACEELA--- 480
           GPT  S PPA+    + P +              S  TRPG        + A E +A   
Sbjct: 78  GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137

Query: 481 -------LALSRGLQLDTQ-----RSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDY 528
                   ALS G + DT        S    + S    T+   P  +    P   ++   
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197

Query: 529 FSVSGDQEADQQEFDKSS----------TIPRNSDISQSYRRMFQAKRPASTA-GLP-TT 576
            SVS   E    E   ++            P +  +S S   +    R   +A G P   
Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257

Query: 577 LGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI---PIKTPVIPV-KTPTVPDLPGVLPA 632
             P+   P      R P   P  +      GP+   P+ TP      +P+ P     LP+
Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317

Query: 633 PPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPE 692
           PP  P  +   S  SP++      + S P S          PL  P P  P     A+P 
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLS----------PLATPPPQAPP--ALALPP 365

Query: 693 SEAEDQEREPPSATVSPGQIPESDPADLSP 722
            +A      PPS   SP   P + P+  +P
Sbjct: 366 LQA------PPSPPASPPLSPLATPSPQAP 389



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 39/168 (23%)

Query: 564 AKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP--IKTPVIPVKTP 621
           A  P   A  P    PA+ TP +  +   P++ P       G  P       P+ P+ TP
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-------GQAPFSPSASLPMSPLATP 519

Query: 622 TVPDLPGVLPAP----PDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPG 677
             P  P VL AP    P  P       P SP++                 QA   PP PG
Sbjct: 520 P-PQAPPVLAAPLLQVPPSP-------PASPTL-----------------QAPRRPPTPG 554

Query: 678 PKPSIPEEH-RQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
           P  S+       A+         R P S    P     S  A  +P +
Sbjct: 555 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 602



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 44/169 (26%), Positives = 59/169 (34%), Gaps = 29/169 (17%)

Query: 564 AKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTV 623
           A  P S    P+   P  +   +     +P   P V+         P   P  P  +P+ 
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA--------PFSPPASPPVSPSA 425

Query: 624 ---PDLPGVLPAPP-DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPK 679
                 P  L APP   P       P SPS    PQ     P  + +    +  P P   
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPPLAAPPLQLAKPPPQAP 481

Query: 680 PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADL--SPRDTP 726
           P++     QA+P          PP++   PGQ P S  A L  SP  TP
Sbjct: 482 PALATPPLQALP---------SPPAS--FPGQAPFSPSASLPMSPLATP 519


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 150/675 (22%), Positives = 229/675 (33%), Gaps = 110/675 (16%)

Query: 113  EEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQ--KKAKKGRGDIQPQLDSALQDVN 170
            E +K    Q + +H +E+K  RQ++++KS    K++  +K ++ + + Q Q     Q   
Sbjct: 1734 ELFKDPLKQRESEHEQEWK-FRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQ---QQFG 1789

Query: 171  DKYLLLE---ETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDLK 227
             ++LL++   +T    ++  L  + G     +S  +   +E  +     T   T S+D+ 
Sbjct: 1790 SQHLLVQSGSDTPSSGIQSPLTPQPGN--GNMSPAQSFHKELFTKQPPSTPTSTSSDDVF 1847

Query: 228  SLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRS 287
                 P   P+ S   I D      S S       PS  +    S  S   S     ++ 
Sbjct: 1848 VKPQAPPPPPAPSRIPIQD------SLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKM 1901

Query: 288  SGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPM--------- 338
             G+    P  H   R ++ A   PV   +  S  S  +  +   +  PSP+         
Sbjct: 1902 VGTPRPPPVGHSFSRRNSAA---PVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTT 1958

Query: 339  -------PPEAPNQL-------SNGFSHYSLSSESHV-GPTGAGLFPHCLPASRLLPRVT 383
                   PP+ P  +       S G S   + SE    GP  AG   H    S       
Sbjct: 1959 NNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQ 2018

Query: 384  SVHLPD-YAHYYTI------GPGMF-------PSSQIP-----SWKDWAKPGPYDQPLVN 424
               +PD YA           GPG F       PSSQ P              PY++P + 
Sbjct: 2019 RQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALT 2078

Query: 425  T--LQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALA 482
               +      +  DP    P T    PA  E    P      A ++PG       +   +
Sbjct: 2079 PRPIDNFSHNQSNDPYSQPPLTPH--PAVNESFAHPSR----AFSQPGTISRPTSQDPYS 2132

Query: 483  LSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEF 542
               G    T R   DS   SSG +   T P       P   +  D +S          + 
Sbjct: 2133 QPPG----TPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTT-VDPYSQQPQTPRPSTQT 2187

Query: 543  DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVAT-IRRTPSTKPSVRR 601
            D   T   N   S  Y       RP  +  +P +  PA   P ++    R+  T+P +  
Sbjct: 2188 DLFVTPVTNQRHSDPYAHPPGTPRPGIS--VPYSQPPATPRPRISEGFTRSSMTRPVL-- 2243

Query: 602  GTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPD---------GPEERGEHSPESPSVG- 651
                   +P + P +       P LPG L  PPD         GP      S  SPS   
Sbjct: 2244 -------MPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAAR 2296

Query: 652  ----EGPQGVTSMPSSMWSGQAS---VNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPS 704
                + P    S   S  + Q +    + P PG + S       A   S    Q ++   
Sbjct: 2297 DPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSF-----CASSNSPMHSQGQQFSG 2351

Query: 705  ATVSPGQIPESDPAD 719
             +  PG +P S   D
Sbjct: 2352 VSQLPGPVPTSGVTD 2366



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 47/216 (21%), Positives = 70/216 (32%), Gaps = 29/216 (13%)

Query: 534  DQEADQQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTP 593
            D+E  Q  +  + T    + + Q          PAS    P  +    +  G AT     
Sbjct: 3871 DEEEKQAMYSSTDTF---THLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELA 3927

Query: 594  STKPSV--RRGTIGAGPIPIKTPVIP---------VKTPTVPDLPGVLPAPPDGPEER-- 640
                 +     T   GP P + P  P          + P   D+P  LP PP   +E   
Sbjct: 3928 GKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELR 3987

Query: 641  ------GEHSPESPSVGEGPQGVTSMPSSMWSGQASV--NPPLPGPKPSIPEEHRQAIPE 692
                     +P+S      P+ V  +  S +   + V   PP P P P IP      +P 
Sbjct: 3988 IQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIP-----ILPS 4042

Query: 693  SEAEDQEREPPSATVSPGQIPESDPADLSPRDTPQG 728
            +  +  E         PG +  + P   SP     G
Sbjct: 4043 TAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSG 4078



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 69/324 (21%), Positives = 113/324 (34%), Gaps = 30/324 (9%)

Query: 221  TISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKSSVCSSLNSV 280
            ++S+  + L++DP++ P+ + + I +   +  +  Y  PP +P   ++   +  S   S 
Sbjct: 2059 SVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQ 2118

Query: 281  NSSDSRSSGSHSHS-PSSHYRYRSSNLAQQAPVRLSSVS--SHDSGFISQDAFQSKSPSP 337
              + SR +    +S P    R    + +Q +    S+    S   G          S  P
Sbjct: 2119 PGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQP 2178

Query: 338  MPPEAPNQLSNGFSHYS--LSSESHVGPTGA---GL-FPHCLPASRLLPRVTSVHLPDYA 391
              P    Q     +  +    S+ +  P G    G+  P+  P +   PR++        
Sbjct: 2179 QTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSM 2238

Query: 392  HYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAA 451
                + P   P  Q    +  A PGP  +P     Q     R P P G   T +   P+A
Sbjct: 2239 TRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQ---TPRPPGP-GLSDTFSRVSPSA 2294

Query: 452  A-----EEAQRPRSMTVSAAT-----------RPGEEMEACEELALAL-SRGLQLDTQRS 494
            A     +    PRS + S  T           RPG E   C      + S+G Q      
Sbjct: 2295 ARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQ 2354

Query: 495  SRDSLQCSSGYSTQTTTPCCSEDT 518
                +  S    TQ T      DT
Sbjct: 2355 LPGPVPTSGVTDTQNTVNMAQADT 2378


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 107/453 (23%), Positives = 161/453 (35%), Gaps = 76/453 (16%)

Query: 269  RKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFISQD 328
            RKSS+ SS++  +SS S SS + +    +  +   +  +  AP      S          
Sbjct: 888  RKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPP----FPCP 943

Query: 329  AFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLL--PR-VTSV 385
            A +S    P PP       +   H    S     P    L P C P    L  PR   S 
Sbjct: 944  ADRSPFLPPPPPVTDCSQGSPLPH----SPVFPPPPPEALIPFCSPPDWCLSPPRPALSP 999

Query: 386  HLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTA 445
             LPD      + P + PSS+ P       P P   P     +  K+ R P  N G P ++
Sbjct: 1000 ILPDSPVSLPLPPPLLPSSEPP-------PAPPLDP-----KFMKDTRPPFTNSGQPESS 1047

Query: 446  SG---PPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCS 502
             G   PP+  EE  RP    ++         EA + + L   R      + S  ++ Q S
Sbjct: 1048 RGSLRPPSTKEETSRPPMPLITT--------EALQMVQLRPVR------KNSGAEAAQLS 1093

Query: 503  SGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMF 562
               + +  TP   +  +          S + + E++ Q    +S++P  +  S       
Sbjct: 1094 ERTAQEQRTPVAPQYHLKPSAFLKSRNSTN-EMESESQPASVTSSLPTPAKSSSQGDHGS 1152

Query: 563  QAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTP- 621
             A+R     G P +  P   + G A  R +PST P          P   K P + +  P 
Sbjct: 1153 AAER-----GGPVSRSPGAPSAGEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPP 1207

Query: 622  -----------TVPDLPGVLPAPPDGPEERGEHSPES----------------PSVGEGP 654
                        V +    +P+P  G EE   HS E+                 SV EG 
Sbjct: 1208 PQKDFAVEPAENVSEALRAVPSPTTG-EEGSVHSREAKESSAAQAGSHATHPGTSVLEGG 1266

Query: 655  QGVTSMPSSMWSGQASVNPPL-PGPKPSIPEEH 686
               +  PS + +    V P + P PK   P E+
Sbjct: 1267 AAGSMSPSRVEANVPMVQPDVSPAPKQEEPAEN 1299



 Score = 36.6 bits (83), Expect = 0.088
 Identities = 61/295 (20%), Positives = 103/295 (34%), Gaps = 59/295 (20%)

Query: 432  KREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATR-PGEEMEACEELALALSRGLQLD 490
            + +P    GG +T+SG P      +  +  + +   + PG  ++             ++ 
Sbjct: 790  QEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKP------------KIM 837

Query: 491  TQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPR 550
            +   S   +  SSGYS+Q+ TP       P  V        +G  +   +  ++ S++  
Sbjct: 838  SPEKSHRVISPSSGYSSQSNTPTA---LTPVPVFLKSVSPANGKGKPKPKVPERKSSLIS 894

Query: 551  NSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP 610
            +  IS S                 T+L  +  T G  T+++            +G+ P P
Sbjct: 895  SVSISSS----------------STSLSSSTSTEGSGTMKKLDP--------AVGSPPAP 930

Query: 611  IKTPVIPVKTPTVPDLPGVLPAPPDGPE-ERGEHSPESPSVGEGPQGVTSMPSSMWSGQA 669
               PV     P   D    LP PP   +  +G   P SP V   P     +P        
Sbjct: 931  PPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSP-VFPPPPPEALIPFCS-PPDW 988

Query: 670  SVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
             ++PP P   P +P+                 P S  + P  +P S+P    P D
Sbjct: 989  CLSPPRPALSPILPD----------------SPVSLPLPPPLLPSSEPPPAPPLD 1027



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 39/174 (22%), Positives = 64/174 (36%), Gaps = 35/174 (20%)

Query: 601 RGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSP------------ESP 648
           + T+ AG     + +    TP V  L G  P+  D    + E++             E P
Sbjct: 739 QSTVSAG-----SSMTSATTPNVYSLCGATPSQSDTSSVKSEYTDPWGYYIDYTGMQEDP 793

Query: 649 SVGEGPQGVTSMPSSMWSGQASVN----------PPLPG----PKPSIPEE-HRQAIPES 693
                P G  S  S + +G   V           P +PG    PK   PE+ HR   P S
Sbjct: 794 G---NPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSS 850

Query: 694 EAEDQEREPPSATVSPGQIPESDPADLSPRDTPQGEDMLNAIRRGVKLKKTTTN 747
               Q   P + T  P  +    PA+   +  P+  +  +++   V +  ++T+
Sbjct: 851 GYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTS 904


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 110/470 (23%), Positives = 163/470 (34%), Gaps = 80/470 (17%)

Query: 285 SRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFISQDAFQSKSPSPMPPEAPN 344
           +RS+G+ S +P+S  R  +S   ++AP                    +K+ SP P  +P 
Sbjct: 80  TRSAGTSSRNPAS--RPPASGRGERAP-------------------PAKNTSPGPVSSPG 118

Query: 345 QLSN-------GFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYAHYYTIG 397
           + S        G     +S+E  V    A   P     S    R TS   P      T  
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG-----TPS 173

Query: 398 PGMFPSSQIPSWK-DWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGP-----PAA 451
           P M   S+    +    +P P  +P   T   RK       +    TT   P     P+A
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS---TTEPSPAARRRPSA 230

Query: 452 AEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTT 511
               QRP S ++S++  P          A    R     +Q   +  LQ       Q T 
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK-GLQALR--PPQVTP 287

Query: 512 PCCSEDTIPS--QVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMFQAKRPAS 569
           P   +D  P+   +S     + S       Q        P +S ++           P+ 
Sbjct: 288 P--RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345

Query: 570 TAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPI------KTPVIPVKTPTV 623
           +A            P + T+   P+T PS    ++G+  +          P+ P+ TP  
Sbjct: 346 SA-----------PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP- 393

Query: 624 PDLPGVLPAPP-DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQAS--VNPPLPGP-- 678
           P  P  L  PP   P       P SP     PQ   ++   +     S   +PP+  P  
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453

Query: 679 KPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD--LSPRDTP 726
            P+ P     A P S+A      PPS    P Q+P S PA   +SP  TP
Sbjct: 454 PPASPPVSPSATPPSQA------PPSLAAPPLQVPPSPPASPPMSPSATP 497



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 43/168 (25%), Positives = 56/168 (33%), Gaps = 39/168 (23%)

Query: 564 AKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP--IKTPVIPVKTP 621
           A  P   A  P    PA+ TP +  +   P++ P       G  P       P+ P+ TP
Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-------GQAPFSPSASLPMSPLATP 558

Query: 622 TVPDLPGVLPAP----PDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPG 677
             P  P VL AP    P  P       P SP++                 QA   PP PG
Sbjct: 559 P-PQAPPVLAAPLLQVPPSP-------PASPTL-----------------QAPRRPPTPG 593

Query: 678 PKPSIPEEH-RQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
           P  S+       A+         R P S    P     S  A  +P +
Sbjct: 594 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 641



 Score = 34.3 bits (77), Expect = 0.44
 Identities = 44/169 (26%), Positives = 59/169 (34%), Gaps = 29/169 (17%)

Query: 564 AKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTV 623
           A  P S    P+   P  +   +     +P   P V+         P   P  P  +P+ 
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA--------PFSPPASPPVSPSA 464

Query: 624 ---PDLPGVLPAPP-DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPK 679
                 P  L APP   P       P SPS    PQ     P  + +    +  P P   
Sbjct: 465 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPPLAAPPLQLAKPPPQAP 520

Query: 680 PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADL--SPRDTP 726
           P++     QA+P          PP++   PGQ P S  A L  SP  TP
Sbjct: 521 PALATPPLQALP---------SPPAS--FPGQAPFSPSASLPMSPLATP 558



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 35/134 (26%), Positives = 49/134 (36%), Gaps = 9/134 (6%)

Query: 627 PGVL-PAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQAS-----VNPPLPGPKP 680
           PG+L P PP  P      +P +  V      V   P +  +G         + P  GP  
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 681 SIPEEHRQAIPESEAEDQ-EREPPSATVSPGQIPESDPADLSPRDTPQGED--MLNAIRR 737
           S     R       A  + ER PP+   SPG +     A  + R  P G+    ++A   
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 738 GVKLKKTTTNDRSA 751
             + K T    RSA
Sbjct: 142 VARGKATEAPKRSA 155


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 55/238 (23%), Positives = 85/238 (35%), Gaps = 20/238 (8%)

Query: 496 RDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNS--D 553
           R SL  +S  S +T+     E T+ ++ +       S D +       ++ +I + S  D
Sbjct: 127 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 186

Query: 554 ISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP--I 611
           ++ + + + +    A T    TT GPA+ TP   T      T P     T    P P  I
Sbjct: 187 LAPTSKVLAKPTPKAET----TTKGPALTTPKEPT-----PTTPKEPASTTPKEPTPTTI 237

Query: 612 KTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASV 671
           K+     K P  P      P  P  P       P   +  E     T  P+   +  A  
Sbjct: 238 KSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 296

Query: 672 NPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPR 723
            P  P P       P+ P+E     P+       +EP   T  P      +PA  +P+
Sbjct: 297 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 354



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 40/165 (24%), Positives = 58/165 (35%), Gaps = 20/165 (12%)

Query: 565 KRPASTAG---LPTTLGPAMVTPG--VATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVK 619
           K PAST      PTT+  A  TP     T  ++  T P     T    P P  TP  P  
Sbjct: 222 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAP 280

Query: 620 TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPK 679
           T T    P    + P  P+E    +P+ P+     +   + P                P 
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------------PT 326

Query: 680 PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
           P+ P+E      E      +   P+A   P      +PA  +P++
Sbjct: 327 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 371



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 74/326 (22%), Positives = 119/326 (36%), Gaps = 57/326 (17%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    + T P E      + A   ++    
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
            T +S+  + +  S  +T+   P   ++  P+          +  + A     + + T P
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT----------TPKKPAPTTPKEPAPTTP 455

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
                          K PA T    TT  PA  TP      + P+  P+  + T    P 
Sbjct: 456 ---------------KEPAPT----TTKKPAPTTP------KEPA--PTTPKETAPTTPK 488

Query: 610 PIKTPVIPVK-TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQ 668
            + TP  P K  PT P+ P      P  PEE    +PE P+     +   + P +     
Sbjct: 489 KL-TPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA----- 537

Query: 669 ASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES--DPADLSPRDTP 726
           A+ N P   P P+ P+E     P+  A    +E  + T   G  P +  +PA  +P+  P
Sbjct: 538 AAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTPKGTAPTTLKEPAPTTPK-KP 594

Query: 727 QGEDMLNAIRRGVKLKKTTTNDRSAP 752
             +++        K   +TT D+ AP
Sbjct: 595 APKELAPTT---TKEPTSTTCDKPAP 617



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/322 (19%), Positives = 102/322 (31%), Gaps = 27/322 (8%)

Query: 421 PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480
           P  +T Q  K    P      P           +  +  S+TV+  T   E  E      
Sbjct: 102 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-ETKETTTTNK 160

Query: 481 LALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQ 540
              + G +  T      S++ +S      T+   ++ T  ++ +       +  +     
Sbjct: 161 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 220

Query: 541 EFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTP---GVATIRRTPSTKP 597
             + +ST P+    +         K PA     PTT   A  TP      T +    T P
Sbjct: 221 PKEPASTTPKEPTPTTIKSAPTTPKEPA-----PTTTKSAPTTPKEPAPTTTKEPAPTTP 275

Query: 598 SVRRGTIGAGPIPIKTPVIPVK----TPTVPDLPGVLPAPPDGPEERGEHSPE--SPSVG 651
                T    P P  T   P       PT P  P      P  P+E    +P+  +P+  
Sbjct: 276 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-----PTTPKEPAPTTPKEPTPTTP 330

Query: 652 EGPQGVTSMPSSMWSGQ-ASVNPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPS 704
           + P   T  P+     + A   P  P P       P+ P+E      +  +    +EP  
Sbjct: 331 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 390

Query: 705 ATVSPGQIPESDPADLSPRDTP 726
            T         +PA  + +  P
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAP 412



 Score = 37.0 bits (84), Expect = 0.068
 Identities = 63/310 (20%), Positives = 99/310 (31%), Gaps = 63/310 (20%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    A T P E      +           
Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK----------- 480

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
           +T  ++   L  ++      TTP     T P +++       + ++       + + T P
Sbjct: 481 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTP 535

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
           + +  +         K PA T    T   PA  TP          T P+  +GT    P 
Sbjct: 536 KAAAPNTP-------KEPAPT----TPKEPAPTTPKEPAPTTPKETAPTTPKGT---APT 581

Query: 610 PIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQA 669
            +K P      PT P  P         P+E    + + P+     +   + P     G A
Sbjct: 582 TLKEPA-----PTTPKKPA--------PKELAPTTTKEPTSTTCDKPAPTTPK----GTA 624

Query: 670 SVNPPLPGPKPSIPEEHRQAIPESEAEDQEREP--------------PSATVSPGQIPES 715
              P  P P  + P+E     P+  A    +EP              P+ T  P      
Sbjct: 625 PTTPKEPAP--TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682

Query: 716 DPADLSPRDT 725
            PA  +P++T
Sbjct: 683 KPAPTTPKET 692



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 36/172 (20%), Positives = 60/172 (34%), Gaps = 18/172 (10%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P G  PTT   P  A    ++P    ++  T  G      ++ A    +    
Sbjct: 637 KEPAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 694

Query: 490 DTQRSSRDSLQCSSGYST-QTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI 548
            T +    +       +T +T  P  SE + P+   +      S D+   +   + +   
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754

Query: 549 PRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR 600
             NS            K P    G+PTT  PA   P + T  +  +T+  +R
Sbjct: 755 LENS-----------PKEP----GVPTTKTPAATKPEMTTTAKDKTTERDLR 791


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 55/238 (23%), Positives = 85/238 (35%), Gaps = 20/238 (8%)

Query: 496 RDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNS--D 553
           R SL  +S  S +T+     E T+ ++ +       S D +       ++ +I + S  D
Sbjct: 168 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 227

Query: 554 ISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP--I 611
           ++ + + + +    A T    TT GPA+ TP   T      T P     T    P P  I
Sbjct: 228 LAPTSKVLAKPTPKAET----TTKGPALTTPKEPT-----PTTPKEPASTTPKEPTPTTI 278

Query: 612 KTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASV 671
           K+     K P  P      P  P  P       P   +  E     T  P+   +  A  
Sbjct: 279 KSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 337

Query: 672 NPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPR 723
            P  P P       P+ P+E     P+       +EP   T  P      +PA  +P+
Sbjct: 338 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 395



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 40/165 (24%), Positives = 58/165 (35%), Gaps = 20/165 (12%)

Query: 565 KRPASTAG---LPTTLGPAMVTPG--VATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVK 619
           K PAST      PTT+  A  TP     T  ++  T P     T    P P  TP  P  
Sbjct: 263 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAP 321

Query: 620 TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPK 679
           T T    P    + P  P+E    +P+ P+     +   + P                P 
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------------PT 367

Query: 680 PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
           P+ P+E      E      +   P+A   P      +PA  +P++
Sbjct: 368 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 412



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 74/326 (22%), Positives = 119/326 (36%), Gaps = 57/326 (17%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    + T P E      + A   ++    
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
            T +S+  + +  S  +T+   P   ++  P+          +  + A     + + T P
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT----------TPKKPAPTTPKEPAPTTP 496

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
                          K PA T    TT  PA  TP      + P+  P+  + T    P 
Sbjct: 497 ---------------KEPAPT----TTKKPAPTTP------KEPA--PTTPKETAPTTPK 529

Query: 610 PIKTPVIPVK-TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQ 668
            + TP  P K  PT P+ P      P  PEE    +PE P+     +   + P +     
Sbjct: 530 KL-TPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA----- 578

Query: 669 ASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES--DPADLSPRDTP 726
           A+ N P   P P+ P+E     P+  A    +E  + T   G  P +  +PA  +P+  P
Sbjct: 579 AAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTPKGTAPTTLKEPAPTTPK-KP 635

Query: 727 QGEDMLNAIRRGVKLKKTTTNDRSAP 752
             +++        K   +TT D+ AP
Sbjct: 636 APKELAPTT---TKEPTSTTCDKPAP 658



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/322 (19%), Positives = 102/322 (31%), Gaps = 27/322 (8%)

Query: 421 PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480
           P  +T Q  K    P      P           +  +  S+TV+  T   E  E      
Sbjct: 143 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-ETKETTTTNK 201

Query: 481 LALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQ 540
              + G +  T      S++ +S      T+   ++ T  ++ +       +  +     
Sbjct: 202 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 261

Query: 541 EFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTP---GVATIRRTPSTKP 597
             + +ST P+    +         K PA     PTT   A  TP      T +    T P
Sbjct: 262 PKEPASTTPKEPTPTTIKSAPTTPKEPA-----PTTTKSAPTTPKEPAPTTTKEPAPTTP 316

Query: 598 SVRRGTIGAGPIPIKTPVIPVK----TPTVPDLPGVLPAPPDGPEERGEHSPE--SPSVG 651
                T    P P  T   P       PT P  P      P  P+E    +P+  +P+  
Sbjct: 317 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-----PTTPKEPAPTTPKEPTPTTP 371

Query: 652 EGPQGVTSMPSSMWSGQ-ASVNPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPS 704
           + P   T  P+     + A   P  P P       P+ P+E      +  +    +EP  
Sbjct: 372 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 431

Query: 705 ATVSPGQIPESDPADLSPRDTP 726
            T         +PA  + +  P
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAP 453



 Score = 37.0 bits (84), Expect = 0.068
 Identities = 63/310 (20%), Positives = 99/310 (31%), Gaps = 63/310 (20%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    A T P E      +           
Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK----------- 521

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
           +T  ++   L  ++      TTP     T P +++       + ++       + + T P
Sbjct: 522 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTP 576

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
           + +  +         K PA T    T   PA  TP          T P+  +GT    P 
Sbjct: 577 KAAAPNTP-------KEPAPT----TPKEPAPTTPKEPAPTTPKETAPTTPKGT---APT 622

Query: 610 PIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQA 669
            +K P      PT P  P         P+E    + + P+     +   + P     G A
Sbjct: 623 TLKEPA-----PTTPKKPA--------PKELAPTTTKEPTSTTCDKPAPTTPK----GTA 665

Query: 670 SVNPPLPGPKPSIPEEHRQAIPESEAEDQEREP--------------PSATVSPGQIPES 715
              P  P P  + P+E     P+  A    +EP              P+ T  P      
Sbjct: 666 PTTPKEPAP--TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723

Query: 716 DPADLSPRDT 725
            PA  +P++T
Sbjct: 724 KPAPTTPKET 733



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 36/172 (20%), Positives = 60/172 (34%), Gaps = 18/172 (10%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P G  PTT   P  A    ++P    ++  T  G      ++ A    +    
Sbjct: 678 KEPAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 735

Query: 490 DTQRSSRDSLQCSSGYST-QTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI 548
            T +    +       +T +T  P  SE + P+   +      S D+   +   + +   
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795

Query: 549 PRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR 600
             NS            K P    G+PTT  PA   P + T  +  +T+  +R
Sbjct: 796 LENS-----------PKEP----GVPTTKTPAATKPEMTTTAKDKTTERDLR 832


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 55/238 (23%), Positives = 85/238 (35%), Gaps = 20/238 (8%)

Query: 496 RDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNS--D 553
           R SL  +S  S +T+     E T+ ++ +       S D +       ++ +I + S  D
Sbjct: 220 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 279

Query: 554 ISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP--I 611
           ++ + + + +    A T    TT GPA+ TP   T      T P     T    P P  I
Sbjct: 280 LAPTSKVLAKPTPKAET----TTKGPALTTPKEPT-----PTTPKEPASTTPKEPTPTTI 330

Query: 612 KTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASV 671
           K+     K P  P      P  P  P       P   +  E     T  P+   +  A  
Sbjct: 331 KSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 389

Query: 672 NPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPR 723
            P  P P       P+ P+E     P+       +EP   T  P      +PA  +P+
Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 447



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 40/165 (24%), Positives = 58/165 (35%), Gaps = 20/165 (12%)

Query: 565 KRPASTAG---LPTTLGPAMVTPG--VATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVK 619
           K PAST      PTT+  A  TP     T  ++  T P     T    P P  TP  P  
Sbjct: 315 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAP 373

Query: 620 TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPK 679
           T T    P    + P  P+E    +P+ P+     +   + P                P 
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------------PT 419

Query: 680 PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
           P+ P+E      E      +   P+A   P      +PA  +P++
Sbjct: 420 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 464



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 74/326 (22%), Positives = 119/326 (36%), Gaps = 57/326 (17%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    + T P E      + A   ++    
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
            T +S+  + +  S  +T+   P   ++  P+          +  + A     + + T P
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT----------TPKKPAPTTPKEPAPTTP 548

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
                          K PA T    TT  PA  TP      + P+  P+  + T    P 
Sbjct: 549 ---------------KEPAPT----TTKKPAPTTP------KEPA--PTTPKETAPTTPK 581

Query: 610 PIKTPVIPVK-TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQ 668
            + TP  P K  PT P+ P      P  PEE    +PE P+     +   + P +     
Sbjct: 582 KL-TPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA----- 630

Query: 669 ASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES--DPADLSPRDTP 726
           A+ N P   P P+ P+E     P+  A    +E  + T   G  P +  +PA  +P+  P
Sbjct: 631 AAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTPKGTAPTTLKEPAPTTPK-KP 687

Query: 727 QGEDMLNAIRRGVKLKKTTTNDRSAP 752
             +++        K   +TT D+ AP
Sbjct: 688 APKELAPTT---TKEPTSTTCDKPAP 710



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/322 (19%), Positives = 102/322 (31%), Gaps = 27/322 (8%)

Query: 421 PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480
           P  +T Q  K    P      P           +  +  S+TV+  T   E  E      
Sbjct: 195 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-ETKETTTTNK 253

Query: 481 LALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQ 540
              + G +  T      S++ +S      T+   ++ T  ++ +       +  +     
Sbjct: 254 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 313

Query: 541 EFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTP---GVATIRRTPSTKP 597
             + +ST P+    +         K PA     PTT   A  TP      T +    T P
Sbjct: 314 PKEPASTTPKEPTPTTIKSAPTTPKEPA-----PTTTKSAPTTPKEPAPTTTKEPAPTTP 368

Query: 598 SVRRGTIGAGPIPIKTPVIPVK----TPTVPDLPGVLPAPPDGPEERGEHSPE--SPSVG 651
                T    P P  T   P       PT P  P      P  P+E    +P+  +P+  
Sbjct: 369 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-----PTTPKEPAPTTPKEPTPTTP 423

Query: 652 EGPQGVTSMPSSMWSGQ-ASVNPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPS 704
           + P   T  P+     + A   P  P P       P+ P+E      +  +    +EP  
Sbjct: 424 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 483

Query: 705 ATVSPGQIPESDPADLSPRDTP 726
            T         +PA  + +  P
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAP 505



 Score = 37.0 bits (84), Expect = 0.068
 Identities = 63/310 (20%), Positives = 99/310 (31%), Gaps = 63/310 (20%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    A T P E      +           
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK----------- 573

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
           +T  ++   L  ++      TTP     T P +++       + ++       + + T P
Sbjct: 574 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTP 628

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
           + +  +         K PA T    T   PA  TP          T P+  +GT    P 
Sbjct: 629 KAAAPNTP-------KEPAPT----TPKEPAPTTPKEPAPTTPKETAPTTPKGT---APT 674

Query: 610 PIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQA 669
            +K P      PT P  P         P+E    + + P+     +   + P     G A
Sbjct: 675 TLKEPA-----PTTPKKPA--------PKELAPTTTKEPTSTTCDKPAPTTPK----GTA 717

Query: 670 SVNPPLPGPKPSIPEEHRQAIPESEAEDQEREP--------------PSATVSPGQIPES 715
              P  P P  + P+E     P+  A    +EP              P+ T  P      
Sbjct: 718 PTTPKEPAP--TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775

Query: 716 DPADLSPRDT 725
            PA  +P++T
Sbjct: 776 KPAPTTPKET 785



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 36/172 (20%), Positives = 60/172 (34%), Gaps = 18/172 (10%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P G  PTT   P  A    ++P    ++  T  G      ++ A    +    
Sbjct: 730 KEPAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 787

Query: 490 DTQRSSRDSLQCSSGYST-QTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI 548
            T +    +       +T +T  P  SE + P+   +      S D+   +   + +   
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847

Query: 549 PRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR 600
             NS            K P    G+PTT  PA   P + T  +  +T+  +R
Sbjct: 848 LENS-----------PKEP----GVPTTKTPAATKPEMTTTAKDKTTERDLR 884


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 55/238 (23%), Positives = 85/238 (35%), Gaps = 20/238 (8%)

Query: 496 RDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNS--D 553
           R SL  +S  S +T+     E T+ ++ +       S D +       ++ +I + S  D
Sbjct: 261 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 320

Query: 554 ISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP--I 611
           ++ + + + +    A T    TT GPA+ TP   T      T P     T    P P  I
Sbjct: 321 LAPTSKVLAKPTPKAET----TTKGPALTTPKEPT-----PTTPKEPASTTPKEPTPTTI 371

Query: 612 KTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASV 671
           K+     K P  P      P  P  P       P   +  E     T  P+   +  A  
Sbjct: 372 KSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 430

Query: 672 NPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPR 723
            P  P P       P+ P+E     P+       +EP   T  P      +PA  +P+
Sbjct: 431 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 488



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 40/165 (24%), Positives = 58/165 (35%), Gaps = 20/165 (12%)

Query: 565 KRPASTAG---LPTTLGPAMVTPG--VATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVK 619
           K PAST      PTT+  A  TP     T  ++  T P     T    P P  TP  P  
Sbjct: 356 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAP 414

Query: 620 TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPK 679
           T T    P    + P  P+E    +P+ P+     +   + P                P 
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--------------PT 460

Query: 680 PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
           P+ P+E      E      +   P+A   P      +PA  +P++
Sbjct: 461 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 505



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 74/326 (22%), Positives = 119/326 (36%), Gaps = 57/326 (17%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    + T P E      + A   ++    
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
            T +S+  + +  S  +T+   P   ++  P+          +  + A     + + T P
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT----------TPKKPAPTTPKEPAPTTP 589

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
                          K PA T    TT  PA  TP      + P+  P+  + T    P 
Sbjct: 590 ---------------KEPAPT----TTKKPAPTTP------KEPA--PTTPKETAPTTPK 622

Query: 610 PIKTPVIPVK-TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQ 668
            + TP  P K  PT P+ P      P  PEE    +PE P+     +   + P +     
Sbjct: 623 KL-TPTTPEKLAPTTPEKPA-----PTTPEELAPTTPEEPTPTTPEEPAPTTPKA----- 671

Query: 669 ASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES--DPADLSPRDTP 726
           A+ N P   P P+ P+E     P+  A    +E  + T   G  P +  +PA  +P+  P
Sbjct: 672 AAPNTP-KEPAPTTPKEPAPTTPKEPAPTTPKE-TAPTTPKGTAPTTLKEPAPTTPK-KP 728

Query: 727 QGEDMLNAIRRGVKLKKTTTNDRSAP 752
             +++        K   +TT D+ AP
Sbjct: 729 APKELAPTT---TKEPTSTTCDKPAP 751



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 63/322 (19%), Positives = 102/322 (31%), Gaps = 27/322 (8%)

Query: 421 PLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELA 480
           P  +T Q  K    P      P           +  +  S+TV+  T   E  E      
Sbjct: 236 PDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV-ETKETTTTNK 294

Query: 481 LALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQ 540
              + G +  T      S++ +S      T+   ++ T  ++ +       +  +     
Sbjct: 295 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 354

Query: 541 EFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTP---GVATIRRTPSTKP 597
             + +ST P+    +         K PA     PTT   A  TP      T +    T P
Sbjct: 355 PKEPASTTPKEPTPTTIKSAPTTPKEPA-----PTTTKSAPTTPKEPAPTTTKEPAPTTP 409

Query: 598 SVRRGTIGAGPIPIKTPVIPVK----TPTVPDLPGVLPAPPDGPEERGEHSPE--SPSVG 651
                T    P P  T   P       PT P  P      P  P+E    +P+  +P+  
Sbjct: 410 KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-----PTTPKEPAPTTPKEPTPTTP 464

Query: 652 EGPQGVTSMPSSMWSGQ-ASVNPPLPGPK------PSIPEEHRQAIPESEAEDQEREPPS 704
           + P   T  P+     + A   P  P P       P+ P+E      +  +    +EP  
Sbjct: 465 KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAP 524

Query: 705 ATVSPGQIPESDPADLSPRDTP 726
            T         +PA  + +  P
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAP 546



 Score = 37.0 bits (84), Expect = 0.068
 Identities = 63/310 (20%), Positives = 99/310 (31%), Gaps = 63/310 (20%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P    PTT   P     +   P +    A T P E      +           
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK----------- 614

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
           +T  ++   L  ++      TTP     T P +++       + ++       + + T P
Sbjct: 615 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTP 669

Query: 550 RNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPI 609
           + +  +         K PA T    T   PA  TP          T P+  +GT    P 
Sbjct: 670 KAAAPNTP-------KEPAPT----TPKEPAPTTPKEPAPTTPKETAPTTPKGT---APT 715

Query: 610 PIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQA 669
            +K P      PT P  P         P+E    + + P+     +   + P     G A
Sbjct: 716 TLKEPA-----PTTPKKPA--------PKELAPTTTKEPTSTTCDKPAPTTPK----GTA 758

Query: 670 SVNPPLPGPKPSIPEEHRQAIPESEAEDQEREP--------------PSATVSPGQIPES 715
              P  P P  + P+E     P+  A    +EP              P+ T  P      
Sbjct: 759 PTTPKEPAP--TTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816

Query: 716 DPADLSPRDT 725
            PA  +P++T
Sbjct: 817 KPAPTTPKET 826



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 36/172 (20%), Positives = 60/172 (34%), Gaps = 18/172 (10%)

Query: 430 KEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
           KE     P G  PTT   P  A    ++P    ++  T  G      ++ A    +    
Sbjct: 771 KEPAPTTPKGTAPTTLKEP--APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 828

Query: 490 DTQRSSRDSLQCSSGYST-QTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTI 548
            T +    +       +T +T  P  SE + P+   +      S D+   +   + +   
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888

Query: 549 PRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR 600
             NS            K P    G+PTT  PA   P + T  +  +T+  +R
Sbjct: 889 LENS-----------PKEP----GVPTTKTPAATKPEMTTTAKDKTTERDLR 925


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 90/408 (22%), Positives = 136/408 (33%), Gaps = 40/408 (9%)

Query: 332 SKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYA 391
           + S +P PP      S+  S  + SS S    + A  FP    AS+ LP       P  +
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP----ASQALPSYPHSFPPPTS 417

Query: 392 HYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAA 451
              +  P  +    +PS   W++  P   P    L        P P   G  + + PP +
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477

Query: 452 A------EEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGY 505
                  ++ Q+ +        +      +      A    L+  +   +       S  
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLG 537

Query: 506 STQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMFQAK 565
           S +   P  +    P     Y     +G   +       SST   +   S          
Sbjct: 538 SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN-SSSSTSQGSYPCSHPSPSQGPQG 596

Query: 566 RPASTAGLPT-TLGPAMVTPGVATIRRTPSTKPSVRR------GTIGAGPIPIKTPVIP- 617
            P     +PT T   A ++  +AT+  +P+   +         G     P   KT   P 
Sbjct: 597 APYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPG 656

Query: 618 --------VKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQA 669
                    +T T P   G   +PP GP   G   P SP+VG GP     +P +  SG  
Sbjct: 657 YKPGSPPSFRTGTPPGYRGT--SPPAGP---GTFKPGSPTVGPGP-----LPPAGPSGLP 706

Query: 670 SVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDP 717
           S+ PP   P    P    Q I +  AE  E E P + V P + P   P
Sbjct: 707 SLPPPPAAPASGPPLSATQ-IKQEPAE--EYETPESPVPPARSPSPPP 751



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 67/308 (21%), Positives = 97/308 (31%), Gaps = 16/308 (5%)

Query: 426 LQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSR 485
           ++ R+ K       G    A GP        R     VS ++  G+  ++ +    A   
Sbjct: 1   MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE 60

Query: 486 GLQLDTQRSSRDSLQCSSGYSTQTTTP--CCSEDTIPSQVSDYDYFSVSGDQEADQQEFD 543
                       S + S   S +T  P    +E  +P   S  D  S+ G    D    D
Sbjct: 61  EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD 120

Query: 544 KSSTIPRNSDISQSYRRMFQAKRPA-STAGLPTTLGPAMVTPGVATIRRTPSTKPSV-RR 601
                  N   S S       +  + S++GL  + GPA           +P    S  R+
Sbjct: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGL--SQGPARPYHPPPLFPPSPQPPDSTPRQ 178

Query: 602 GTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMP 661
                 P P  TP      P  P    +  APP  P    +  P       G  GV S P
Sbjct: 179 PEASFEPHPSVTPT-GYHAPMEPPTSRMFQAPPGAPPPHPQLYPG------GTGGVLSGP 231

Query: 662 SSMWSG---QASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPA 718
                G    +SV  P  G +   P           +     +PP+  V  G +P + P 
Sbjct: 232 PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPP 291

Query: 719 DLSPRDTP 726
              P  TP
Sbjct: 292 ANFPHVTP 299


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 90/408 (22%), Positives = 136/408 (33%), Gaps = 40/408 (9%)

Query: 332 SKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGAGLFPHCLPASRLLPRVTSVHLPDYA 391
           + S +P PP      S+  S  + SS S    + A  FP    AS+ LP       P  +
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP----ASQALPSYPHSFPPPTS 417

Query: 392 HYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAA 451
              +  P  +    +PS   W++  P   P    L        P P   G  + + PP +
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477

Query: 452 A------EEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGY 505
                  ++ Q+ +        +      +      A    L+  +   +       S  
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLG 537

Query: 506 STQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMFQAK 565
           S +   P  +    P     Y     +G   +       SST   +   S          
Sbjct: 538 SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN-SSSSTSQGSYPCSHPSPSQGPQG 596

Query: 566 RPASTAGLPT-TLGPAMVTPGVATIRRTPSTKPSVRR------GTIGAGPIPIKTPVIP- 617
            P     +PT T   A ++  +AT+  +P+   +         G     P   KT   P 
Sbjct: 597 APYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPG 656

Query: 618 --------VKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQA 669
                    +T T P   G   +PP GP   G   P SP+VG GP     +P +  SG  
Sbjct: 657 YKPGSPPSFRTGTPPGYRGT--SPPAGP---GTFKPGSPTVGPGP-----LPPAGPSGLP 706

Query: 670 SVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDP 717
           S+ PP   P    P    Q I +  AE  E E P + V P + P   P
Sbjct: 707 SLPPPPAAPASGPPLSATQ-IKQEPAE--EYETPESPVPPARSPSPPP 751



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 67/308 (21%), Positives = 97/308 (31%), Gaps = 16/308 (5%)

Query: 426 LQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSR 485
           ++ R+ K       G    A GP        R     VS ++  G+  ++ +    A   
Sbjct: 1   MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE 60

Query: 486 GLQLDTQRSSRDSLQCSSGYSTQTTTP--CCSEDTIPSQVSDYDYFSVSGDQEADQQEFD 543
                       S + S   S +T  P    +E  +P   S  D  S+ G    D    D
Sbjct: 61  EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD 120

Query: 544 KSSTIPRNSDISQSYRRMFQAKRPA-STAGLPTTLGPAMVTPGVATIRRTPSTKPSV-RR 601
                  N   S S       +  + S++GL  + GPA           +P    S  R+
Sbjct: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGL--SQGPARPYHPPPLFPPSPQPPDSTPRQ 178

Query: 602 GTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMP 661
                 P P  TP      P  P    +  APP  P    +  P       G  GV S P
Sbjct: 179 PEASFEPHPSVTPT-GYHAPMEPPTSRMFQAPPGAPPPHPQLYPG------GTGGVLSGP 231

Query: 662 SSMWSG---QASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPA 718
                G    +SV  P  G +   P           +     +PP+  V  G +P + P 
Sbjct: 232 PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPP 291

Query: 719 DLSPRDTP 726
              P  TP
Sbjct: 292 ANFPHVTP 299


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 106/489 (21%), Positives = 173/489 (35%), Gaps = 71/489 (14%)

Query: 212 MLGEITHLQTISEDLKSLTMDPHKLPSSSEQVILDLKGSDYSWSYQTPPSSPSTTMSRKS 271
           +LGE T     +  + S +M+   LP S+    L    S+ S ++ + P SP+TT+S  S
Sbjct: 93  LLGEST-----TSPISSGSMETTALPGSTTTPGL----SEKSTTFHSSPRSPATTLSPAS 143

Query: 272 SVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQAPVRLSSVSSHDSGFI------ 325
           +  S + S  S+ S S    +H+ +      +  L++ +    SS  S D+  +      
Sbjct: 144 TTSSGV-SEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 202

Query: 326 SQDAFQSKSPSPMPPEAPNQLSNG------FSHYSLSSESHVGPTGAGLFPHCLPASRLL 379
           S  + +S +    P      LS G      F   S +  S  G T   LFP    +S ++
Sbjct: 203 SGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIV 262

Query: 380 PRVTSVHLPDYAHYYTIGPGMFPSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNG 439
              T VH    +   T+ P    S           PG   +              P P  
Sbjct: 263 EASTRVHSSTGSPRTTLSPASSTS-----------PGLQGESTAFQTHPASTHTTPSP-- 309

Query: 440 GGPTTASGP----------PAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQL 489
             P+TA+ P          P +      P S T S  +       +  + +         
Sbjct: 310 --PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHS 367

Query: 490 DTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIP 549
            T   S +S   S      T T    + T  S +S     S S  Q + +   D + + P
Sbjct: 368 TTSGVSEES-STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS-SQGSTEATLDTTPSPP 425

Query: 550 RNS----DISQSYRRMFQAKRPAST-----AGLPTTLGPAMVTPGVATIRRTP-STKPSV 599
             +    ++S +Y       RP+ST     +   TTLG +  +    T+  +P ST+ + 
Sbjct: 426 GTTAAPVEVSTTYH-----SRPSSTPTTHFSASSTTLGRSEES---TTVHSSPGSTETTA 477

Query: 600 RRGTIGAGPIPIKTPVIPVKTPTVPDL---PGVLPAPPDGPEERGEHSPESPSVGEGPQG 656
             G+     +  K+      +P  PD    P    +     E    HS    +      G
Sbjct: 478 LPGSTTTAGLSEKSTTF-YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG 536

Query: 657 VTSMPSSMW 665
            T+MP   W
Sbjct: 537 STTMPGQHW 545


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 74/325 (22%), Positives = 112/325 (34%), Gaps = 34/325 (10%)

Query: 423 VNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALA 482
           V T   RK      P G  P  A G    AE++    S   S +      +      A +
Sbjct: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS---SSEESDSEEEKTGLAVTVGQAKS 640

Query: 483 LSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEF 542
           + +GLQ+   +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E 
Sbjct: 641 VGKGLQV---KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 697

Query: 543 DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRG 602
             S    + S      +    A R  S  G  +  G  +     A  R     KP VR  
Sbjct: 698 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN- 756

Query: 603 TIGAGPIPIKTPVI---PVKTPTVPDLPGVLPAPPDGPEE-RGEHSPESPSVGEG----- 653
                  P  + V+   P   P+V            GPEE  G    ES S  E      
Sbjct: 757 -------PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 809

Query: 654 --PQGVTSM--------PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPP 703
             P G T            S   G A   P   GP  +   +   +   SE  D + E P
Sbjct: 810 VKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 869

Query: 704 SATVSPGQIPESDPADLSPRDTPQG 728
           +A V+  Q+ +     + P  +P G
Sbjct: 870 AA-VTSAQVIKPPLIFVDPNRSPAG 893



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 62/287 (21%), Positives = 104/287 (36%), Gaps = 36/287 (12%)

Query: 436  DPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSS 495
            DPN   P   +  PA A+ A  PR    S +T      E+ +E  +  ++ L    + + 
Sbjct: 886  DPNRS-PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 944

Query: 496  RDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDIS 555
                      + + +    S     S++SD         QE    +  K +  P +  ++
Sbjct: 945  VTMPTAHPRIAPKASMAGASSSKESSRISD------GKKQEGPATQVSKKN--PASLPLT 996

Query: 556  QSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR-RGTIGAGPIPIKTP 614
            Q+  ++   K   +   +  T   + V   V T+  T     SV+ +GT           
Sbjct: 997  QAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN---------- 1046

Query: 615  VIPVKTPTVPDLPGVLPAPP--DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVN 672
               ++ P +P++     AP   D  E+  + S  S   GEGPQG  S  +          
Sbjct: 1047 --KLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT---------- 1094

Query: 673  PPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
              L GP PS  E   +      +ED    P  + +S    P   PA+
Sbjct: 1095 --LVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1139



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/356 (22%), Positives = 124/356 (34%), Gaps = 85/356 (23%)

Query: 435 PDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEE----MEACEELALALSRGLQLD 490
           P   G   + A   PA A   QRP   + S+     EE    +      A ++ +GLQ+ 
Sbjct: 589 PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV- 647

Query: 491 TQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFD------K 544
             +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E        K
Sbjct: 648 --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 705

Query: 545 SSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLG-------PAMVTPGV------ATIRR 591
           +S     +  + +  R   AK   S  G   T         P+ V P V        + R
Sbjct: 706 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 765

Query: 592 TPSTKPSVRRGTIGA-----GPIP-----------------------------IKTPVIP 617
            P++ PSV +    A     GP                               I+  + P
Sbjct: 766 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 825

Query: 618 VK-------TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM---------- 660
            K        PT P   G   A     ++ G  S ES S GE P  VTS           
Sbjct: 826 AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFV 885

Query: 661 -PSSMWSGQASVNPPLPGPKPSIPEEHRQA-----IPESEAEDQEREPPSATVSPG 710
            P+   +G A+   P      S P + R +        SE+ED++  P +  ++PG
Sbjct: 886 DPNRSPAGPAAT--PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 939



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 43/172 (25%), Positives = 63/172 (36%), Gaps = 29/172 (16%)

Query: 568 ASTAGLPTTLGPAMVTPGVATIRRTPSTK--PSVRRGTIGAGPIPIKTPV-IPVKTPTVP 624
           A +   P  +  A   P +    + P TK  P     T  A   P++     P K  T  
Sbjct: 541 ADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 596

Query: 625 DLPGVLPAPPDGPEERGEHSPESP-------------------SVGEGPQ-GVTSMPSSM 664
              G  PA   G +   E S  S                    SVG+G Q    S+P   
Sbjct: 597 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKG 656

Query: 665 WSGQASVNPPLPGPK-PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES 715
             GQ +  P LPG   P++ +   +   +SE+ ++E +   A  SP Q+  S
Sbjct: 657 SLGQGTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 707


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 74/325 (22%), Positives = 112/325 (34%), Gaps = 34/325 (10%)

Query: 423 VNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALA 482
           V T   RK      P G  P  A G    AE++    S   S +      +      A +
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS---SSEESDSEEEKTGLAVTVGQAKS 717

Query: 483 LSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEF 542
           + +GLQ+   +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E 
Sbjct: 718 VGKGLQV---KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774

Query: 543 DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRG 602
             S    + S      +    A R  S  G  +  G  +     A  R     KP VR  
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN- 833

Query: 603 TIGAGPIPIKTPVI---PVKTPTVPDLPGVLPAPPDGPEE-RGEHSPESPSVGEG----- 653
                  P  + V+   P   P+V            GPEE  G    ES S  E      
Sbjct: 834 -------PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886

Query: 654 --PQGVTSM--------PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPP 703
             P G T            S   G A   P   GP  +   +   +   SE  D + E P
Sbjct: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 946

Query: 704 SATVSPGQIPESDPADLSPRDTPQG 728
           +A V+  Q+ +     + P  +P G
Sbjct: 947 AA-VTSAQVIKPPLIFVDPNRSPAG 970



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/356 (22%), Positives = 124/356 (34%), Gaps = 85/356 (23%)

Query: 435  PDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEE----MEACEELALALSRGLQLD 490
            P   G   + A   PA A   QRP   + S+     EE    +      A ++ +GLQ+ 
Sbjct: 666  PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV- 724

Query: 491  TQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFD------K 544
              +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E        K
Sbjct: 725  --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782

Query: 545  SSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLG-------PAMVTPGV------ATIRR 591
            +S     +  + +  R   AK   S  G   T         P+ V P V        + R
Sbjct: 783  TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842

Query: 592  TPSTKPSVRRGTIGA-----GPIP-----------------------------IKTPVIP 617
             P++ PSV +    A     GP                               I+  + P
Sbjct: 843  GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902

Query: 618  VK-------TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM---------- 660
             K        PT P   G   A     ++ G  S ES S GE P  VTS           
Sbjct: 903  AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFV 962

Query: 661  -PSSMWSGQASVNPPLPGPKPSIPEEHRQA-----IPESEAEDQEREPPSATVSPG 710
             P+   +G A+   P      S P + R +        SE+ED++  P +  ++PG
Sbjct: 963  DPNRSPAGPAAT--PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 1016



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 43/172 (25%), Positives = 63/172 (36%), Gaps = 29/172 (16%)

Query: 568 ASTAGLPTTLGPAMVTPGVATIRRTPSTK--PSVRRGTIGAGPIPIKTPV-IPVKTPTVP 624
           A +   P  +  A   P +    + P TK  P     T  A   P++     P K  T  
Sbjct: 618 ADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673

Query: 625 DLPGVLPAPPDGPEERGEHSPESP-------------------SVGEGPQ-GVTSMPSSM 664
              G  PA   G +   E S  S                    SVG+G Q    S+P   
Sbjct: 674 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKG 733

Query: 665 WSGQASVNPPLPGPK-PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES 715
             GQ +  P LPG   P++ +   +   +SE+ ++E +   A  SP Q+  S
Sbjct: 734 SLGQGTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 41/159 (25%), Positives = 63/159 (39%), Gaps = 22/159 (13%)

Query: 568  ASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIP-----VKTPT 622
            AS AG  ++   + ++ G    +  P+T+     GT+ A   P  T V       ++ P 
Sbjct: 1035 ASMAGASSSKESSRISDGKK--QEGPATQVDSAVGTLPATS-PQSTSVQAKGTNKLRKPK 1091

Query: 623  VPDLPGVLPAPP--DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKP 680
            +P++     AP   D  E+  + S  S   GEGPQG  S  +            L GP P
Sbjct: 1092 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT------------LVGPTP 1139

Query: 681  SIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
            S  E   +      +ED    P  + +S    P   PA+
Sbjct: 1140 SRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1178


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 74/325 (22%), Positives = 112/325 (34%), Gaps = 34/325 (10%)

Query: 423 VNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALA 482
           V T   RK      P G  P  A G    AE++    S   S +      +      A +
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS---SSEESDSEEEKTGLAVTVGQAKS 717

Query: 483 LSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEF 542
           + +GLQ+   +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E 
Sbjct: 718 VGKGLQV---KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774

Query: 543 DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRG 602
             S    + S      +    A R  S  G  +  G  +     A  R     KP VR  
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN- 833

Query: 603 TIGAGPIPIKTPVI---PVKTPTVPDLPGVLPAPPDGPEE-RGEHSPESPSVGEG----- 653
                  P  + V+   P   P+V            GPEE  G    ES S  E      
Sbjct: 834 -------PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886

Query: 654 --PQGVTSM--------PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPP 703
             P G T            S   G A   P   GP  +   +   +   SE  D + E P
Sbjct: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 946

Query: 704 SATVSPGQIPESDPADLSPRDTPQG 728
           +A V+  Q+ +     + P  +P G
Sbjct: 947 AA-VTSAQVIKPPLIFVDPNRSPAG 970



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 61/287 (21%), Positives = 103/287 (35%), Gaps = 37/287 (12%)

Query: 436  DPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSS 495
            DPN   P   +  PA A+ A  PR    S +T      E+ +E  +  ++ L    + + 
Sbjct: 963  DPNRS-PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 1021

Query: 496  RDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDIS 555
                      + + +    S     S++SD         QE    +  K +  P +  ++
Sbjct: 1022 VTMPTAHPRIAPKASMAGASSSKESSRISD------GKKQEGPATQVSKKN--PASLPLT 1073

Query: 556  QSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR-RGTIGAGPIPIKTP 614
            Q+  ++   K   +   +  T   + V   V T+  T     SV+ +GT           
Sbjct: 1074 QAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN---------- 1123

Query: 615  VIPVKTPTVPDLPGVLPAPP--DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVN 672
               ++ P +P++     AP   D  E+  + S  S   GEGPQG  S  +          
Sbjct: 1124 --KLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL--------- 1172

Query: 673  PPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
                GP PS  E   +      +ED    P  + +S    P   PA+
Sbjct: 1173 ----GPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1215



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/356 (22%), Positives = 124/356 (34%), Gaps = 85/356 (23%)

Query: 435  PDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEE----MEACEELALALSRGLQLD 490
            P   G   + A   PA A   QRP   + S+     EE    +      A ++ +GLQ+ 
Sbjct: 666  PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV- 724

Query: 491  TQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFD------K 544
              +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E        K
Sbjct: 725  --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782

Query: 545  SSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLG-------PAMVTPGV------ATIRR 591
            +S     +  + +  R   AK   S  G   T         P+ V P V        + R
Sbjct: 783  TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842

Query: 592  TPSTKPSVRRGTIGA-----GPIP-----------------------------IKTPVIP 617
             P++ PSV +    A     GP                               I+  + P
Sbjct: 843  GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902

Query: 618  VK-------TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM---------- 660
             K        PT P   G   A     ++ G  S ES S GE P  VTS           
Sbjct: 903  AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFV 962

Query: 661  -PSSMWSGQASVNPPLPGPKPSIPEEHRQA-----IPESEAEDQEREPPSATVSPG 710
             P+   +G A+   P      S P + R +        SE+ED++  P +  ++PG
Sbjct: 963  DPNRSPAGPAAT--PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 1016



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 43/172 (25%), Positives = 63/172 (36%), Gaps = 29/172 (16%)

Query: 568 ASTAGLPTTLGPAMVTPGVATIRRTPSTK--PSVRRGTIGAGPIPIKTPV-IPVKTPTVP 624
           A +   P  +  A   P +    + P TK  P     T  A   P++     P K  T  
Sbjct: 618 ADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673

Query: 625 DLPGVLPAPPDGPEERGEHSPESP-------------------SVGEGPQ-GVTSMPSSM 664
              G  PA   G +   E S  S                    SVG+G Q    S+P   
Sbjct: 674 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKG 733

Query: 665 WSGQASVNPPLPGPK-PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES 715
             GQ +  P LPG   P++ +   +   +SE+ ++E +   A  SP Q+  S
Sbjct: 734 SLGQGTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 74/325 (22%), Positives = 112/325 (34%), Gaps = 34/325 (10%)

Query: 423 VNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALA 482
           V T   RK      P G  P  A G    AE++    S   S +      +      A +
Sbjct: 584 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS---SSEESDSEEEKTGLAVTVGQAKS 640

Query: 483 LSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEF 542
           + +GLQ+   +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E 
Sbjct: 641 VGKGLQV---KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 697

Query: 543 DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRG 602
             S    + S      +    A R  S  G  +  G  +     A  R     KP VR  
Sbjct: 698 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN- 756

Query: 603 TIGAGPIPIKTPVI---PVKTPTVPDLPGVLPAPPDGPEE-RGEHSPESPSVGEG----- 653
                  P  + V+   P   P+V            GPEE  G    ES S  E      
Sbjct: 757 -------PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 809

Query: 654 --PQGVTSM--------PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPP 703
             P G T            S   G A   P   GP  +   +   +   SE  D + E P
Sbjct: 810 VKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 869

Query: 704 SATVSPGQIPESDPADLSPRDTPQG 728
           +A V+  Q+ +     + P  +P G
Sbjct: 870 AA-VTSAQVIKPPLIFVDPNRSPAG 893



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 61/287 (21%), Positives = 103/287 (35%), Gaps = 37/287 (12%)

Query: 436  DPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSS 495
            DPN   P   +  PA A+ A  PR    S +T      E+ +E  +  ++ L    + + 
Sbjct: 886  DPNRS-PAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNV 944

Query: 496  RDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDIS 555
                      + + +    S     S++SD         QE    +  K +  P +  ++
Sbjct: 945  VTMPTAHPRIAPKASMAGASSSKESSRISD------GKKQEGPATQVSKKN--PASLPLT 996

Query: 556  QSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVR-RGTIGAGPIPIKTP 614
            Q+  ++   K   +   +  T   + V   V T+  T     SV+ +GT           
Sbjct: 997  QAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTN---------- 1046

Query: 615  VIPVKTPTVPDLPGVLPAPP--DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVN 672
               ++ P +P++     AP   D  E+  + S  S   GEGPQG  S  +          
Sbjct: 1047 --KLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL--------- 1095

Query: 673  PPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
                GP PS  E   +      +ED    P  + +S    P   PA+
Sbjct: 1096 ----GPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1138



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/356 (22%), Positives = 124/356 (34%), Gaps = 85/356 (23%)

Query: 435 PDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEE----MEACEELALALSRGLQLD 490
           P   G   + A   PA A   QRP   + S+     EE    +      A ++ +GLQ+ 
Sbjct: 589 PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV- 647

Query: 491 TQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFD------K 544
             +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E        K
Sbjct: 648 --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 705

Query: 545 SSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLG-------PAMVTPGV------ATIRR 591
           +S     +  + +  R   AK   S  G   T         P+ V P V        + R
Sbjct: 706 TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 765

Query: 592 TPSTKPSVRRGTIGA-----GPIP-----------------------------IKTPVIP 617
            P++ PSV +    A     GP                               I+  + P
Sbjct: 766 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 825

Query: 618 VK-------TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM---------- 660
            K        PT P   G   A     ++ G  S ES S GE P  VTS           
Sbjct: 826 AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFV 885

Query: 661 -PSSMWSGQASVNPPLPGPKPSIPEEHRQA-----IPESEAEDQEREPPSATVSPG 710
            P+   +G A+   P      S P + R +        SE+ED++  P +  ++PG
Sbjct: 886 DPNRSPAGPAAT--PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 939



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 43/172 (25%), Positives = 63/172 (36%), Gaps = 29/172 (16%)

Query: 568 ASTAGLPTTLGPAMVTPGVATIRRTPSTK--PSVRRGTIGAGPIPIKTPV-IPVKTPTVP 624
           A +   P  +  A   P +    + P TK  P     T  A   P++     P K  T  
Sbjct: 541 ADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 596

Query: 625 DLPGVLPAPPDGPEERGEHSPESP-------------------SVGEGPQ-GVTSMPSSM 664
              G  PA   G +   E S  S                    SVG+G Q    S+P   
Sbjct: 597 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKG 656

Query: 665 WSGQASVNPPLPGPK-PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES 715
             GQ +  P LPG   P++ +   +   +SE+ ++E +   A  SP Q+  S
Sbjct: 657 SLGQGTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 707


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 74/325 (22%), Positives = 112/325 (34%), Gaps = 34/325 (10%)

Query: 423 VNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALA 482
           V T   RK      P G  P  A G    AE++    S   S +      +      A +
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS---SSEESDSEEEKTGLAVTVGQAKS 717

Query: 483 LSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEF 542
           + +GLQ+   +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E 
Sbjct: 718 VGKGLQV---KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774

Query: 543 DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRG 602
             S    + S      +    A R  S  G  +  G  +     A  R     KP VR  
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN- 833

Query: 603 TIGAGPIPIKTPVI---PVKTPTVPDLPGVLPAPPDGPEE-RGEHSPESPSVGEG----- 653
                  P  + V+   P   P+V            GPEE  G    ES S  E      
Sbjct: 834 -------PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886

Query: 654 --PQGVTSM--------PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPP 703
             P G T            S   G A   P   GP  +   +   +   SE  D + E P
Sbjct: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 946

Query: 704 SATVSPGQIPESDPADLSPRDTPQG 728
           +A V+  Q+ +     + P  +P G
Sbjct: 947 AA-VTSAQVIKPPLIFVDPNRSPAG 970



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/356 (22%), Positives = 124/356 (34%), Gaps = 85/356 (23%)

Query: 435  PDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEE----MEACEELALALSRGLQLD 490
            P   G   + A   PA A   QRP   + S+     EE    +      A ++ +GLQ+ 
Sbjct: 666  PRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV- 724

Query: 491  TQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFD------K 544
              +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E        K
Sbjct: 725  --KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVK 782

Query: 545  SSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLG-------PAMVTPGV------ATIRR 591
            +S     +  + +  R   AK   S  G   T         P+ V P V        + R
Sbjct: 783  TSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLAR 842

Query: 592  TPSTKPSVRRGTIGA-----GPIP-----------------------------IKTPVIP 617
             P++ PSV +    A     GP                               I+  + P
Sbjct: 843  GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP 902

Query: 618  VK-------TPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSM---------- 660
             K        PT P   G   A     ++ G  S ES S GE P  VTS           
Sbjct: 903  AKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFV 962

Query: 661  -PSSMWSGQASVNPPLPGPKPSIPEEHRQA-----IPESEAEDQEREPPSATVSPG 710
             P+   +G A+   P      S P + R +        SE+ED++  P +  ++PG
Sbjct: 963  DPNRSPAGPAAT--PAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPG 1016



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 43/172 (25%), Positives = 63/172 (36%), Gaps = 29/172 (16%)

Query: 568 ASTAGLPTTLGPAMVTPGVATIRRTPSTK--PSVRRGTIGAGPIPIKTPV-IPVKTPTVP 624
           A +   P  +  A   P +    + P TK  P     T  A   P++     P K  T  
Sbjct: 618 ADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673

Query: 625 DLPGVLPAPPDGPEERGEHSPESP-------------------SVGEGPQ-GVTSMPSSM 664
              G  PA   G +   E S  S                    SVG+G Q    S+P   
Sbjct: 674 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKG 733

Query: 665 WSGQASVNPPLPGPK-PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES 715
             GQ +  P LPG   P++ +   +   +SE+ ++E +   A  SP Q+  S
Sbjct: 734 SLGQGTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784



 Score = 33.5 bits (75), Expect = 0.75
 Identities = 40/159 (25%), Positives = 62/159 (38%), Gaps = 23/159 (14%)

Query: 568  ASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIP-----VKTPT 622
            AS AG  ++   + ++ G    +  P+T+     GT+ A   P  T V       ++ P 
Sbjct: 1035 ASMAGASSSKESSRISDGKK--QEGPATQVDSAVGTLPATS-PQSTSVQAKGTNKLRKPK 1091

Query: 623  VPDLPGVLPAPP--DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKP 680
            +P++     AP   D  E+  + S  S   GEGPQG  S  +              GP P
Sbjct: 1092 LPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTL-------------GPTP 1138

Query: 681  SIPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD 719
            S  E   +      +ED    P  + +S    P   PA+
Sbjct: 1139 SRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPAN 1177


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 85/202 (42%), Gaps = 24/202 (11%)

Query: 539 QQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTP----- 593
           Q+ + +++++   S   Q  + +F+  + ++TA +   +G  ++ PG   ++  P     
Sbjct: 487 QRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASV-VAMGFILINPGTCPVKVLPELPPV 545

Query: 594 ----STKPSVRRGTIGAGPIPIKTPVIPVKTPTV-PDLPGVLPAPPDGPEERGEHSPESP 648
               ST PS   G      I  K P + ++ P+V  + P V    P  P E+   S E P
Sbjct: 546 SPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKP 605

Query: 649 SVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVS 708
           ++   P    +MPS          P +P  KP+I  E +  IP  +      +P  +T  
Sbjct: 606 TI---PSEKPNMPSE--------KPTIPSEKPTILTE-KPTIPSEKPTIPSEKPTISTEK 653

Query: 709 PGQIPESDPADLSPRDTPQGED 730
           P  +P  +P   +   T   E+
Sbjct: 654 P-TVPTEEPTTPTEETTTSMEE 674



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 28/163 (17%)

Query: 547 TIPRNSDISQSYRRMFQAKRPASTAGLPT------TLGPAMVTPGVATIRRTPSTKPSVR 600
           TIP       + +     ++P +    PT      T+ P   T        TP+ KP++ 
Sbjct: 718 TIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPT--------TPTEKPTIS 769

Query: 601 RGTIGAGPIPIKTPVIPVKTPTVP-DLPGVLPAPPDGPEERGEHSPESPSVG-EGP---- 654
              +    IP + P IP + PT+P + P +    P  P E    S E PS+  E P    
Sbjct: 770 PEKL---TIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT 826

Query: 655 -QGVTSMPSSMWSGQASV----NPPLPGPKPSIPEEHRQAIPE 692
            +  TS+  +  S +        P +   KP+IP E     PE
Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 49/212 (23%), Positives = 74/212 (34%), Gaps = 35/212 (16%)

Query: 547 TIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGA 606
           TIP       S +     ++P      PTT  P   T         P+ KPS        
Sbjct: 634 TIPSEKPTIPSEKPTISTEKPTVPTEEPTT--PTEETTTSMEEPVIPTEKPS-------- 683

Query: 607 GPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWS 666
             IP + P IP + PT+     ++        E+   SPE P++   P    ++P+   S
Sbjct: 684 --IPTEKPSIPTEKPTISMEETIIST------EKPTISPEKPTI---PTEKPTIPTEK-S 731

Query: 667 GQASVNPPLPGPKPSIPEEHRQAIPESEAEDQER------------EPPSATVSPGQIPE 714
             +   P  P  KP+IP E     PE      E+            E P+       IP 
Sbjct: 732 TISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791

Query: 715 SDPA-DLSPRDTPQGEDMLNAIRRGVKLKKTT 745
             P        TP  E  ++  +  + ++K T
Sbjct: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 43/180 (23%), Positives = 68/180 (37%), Gaps = 26/180 (14%)

Query: 547 TIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRT-PSTKPSVRRGTIG 605
           TIP       + +    +++P   +  PT        P + T + T PS KP+       
Sbjct: 592 TIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEK---PTILTEKPTIPSEKPT------- 641

Query: 606 AGPIPIKTPVIPVKTPTVPDLPGVLPAP--------PDGPEERGEHSPESPSVGEGPQGV 657
              IP + P I  + PTVP      P          P  P E+     E PS+      +
Sbjct: 642 ---IPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTI 698

Query: 658 TSMPSSMWSGQASVNPP---LPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPE 714
           +   + + + + +++P    +P  KP+IP E     PE      E+ P   T  P   PE
Sbjct: 699 SMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK-PTIPTEKPTISPE 757



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 50/223 (22%), Positives = 82/223 (36%), Gaps = 52/223 (23%)

Query: 507  TQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMFQAKR 566
            T+  T    E T P++ +       S   E      ++++T    + IS     +   K 
Sbjct: 791  TEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP 850

Query: 567  PASTAG--LPT---TLGPAMVTPGVATIRRT-PSTKPSV--RRGTIGAGPIPIKT----- 613
              ST    +PT   T+ P  +T  + T + T P+ KP++     TI    + I T     
Sbjct: 851  TISTEKPTIPTEKPTISPEKLT--IPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTI 908

Query: 614  -----------PVIPVKTPTVP---------------DLPGVLPAPPDGPEERGEHSPES 647
                       P IP + PT+P               + P + P     P E+   S E 
Sbjct: 909  SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEK 968

Query: 648  PSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAI 690
            P++   P    ++P+          P +P  KP+IP E   A+
Sbjct: 969  PTI---PTEKLTIPTE--------KPTIPTEKPTIPTEKLTAL 1000


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 85/202 (42%), Gaps = 24/202 (11%)

Query: 539 QQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTP----- 593
           Q+ + +++++   S   Q  + +F+  + ++TA +   +G  ++ PG   ++  P     
Sbjct: 487 QRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTASV-VAMGFILINPGTCPVKVLPELPPV 545

Query: 594 ----STKPSVRRGTIGAGPIPIKTPVIPVKTPTV-PDLPGVLPAPPDGPEERGEHSPESP 648
               ST PS   G      I  K P + ++ P+V  + P V    P  P E+   S E P
Sbjct: 546 SPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKP 605

Query: 649 SVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVS 708
           ++   P    +MPS          P +P  KP+I  E +  IP  +      +P  +T  
Sbjct: 606 TI---PSEKPNMPSE--------KPTIPSEKPTILTE-KPTIPSEKPTIPSEKPTISTEK 653

Query: 709 PGQIPESDPADLSPRDTPQGED 730
           P  +P  +P   +   T   E+
Sbjct: 654 P-TVPTEEPTTPTEETTTSMEE 674



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 42/163 (25%), Positives = 64/163 (39%), Gaps = 28/163 (17%)

Query: 547 TIPRNSDISQSYRRMFQAKRPASTAGLPT------TLGPAMVTPGVATIRRTPSTKPSVR 600
           TIP       + +     ++P +    PT      T+ P   T        TP+ KP++ 
Sbjct: 718 TIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPT--------TPTEKPTIS 769

Query: 601 RGTIGAGPIPIKTPVIPVKTPTVP-DLPGVLPAPPDGPEERGEHSPESPSVG-EGP---- 654
              +    IP + P IP + PT+P + P +    P  P E    S E PS+  E P    
Sbjct: 770 PEKL---TIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT 826

Query: 655 -QGVTSMPSSMWSGQASV----NPPLPGPKPSIPEEHRQAIPE 692
            +  TS+  +  S +        P +   KP+IP E     PE
Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 49/212 (23%), Positives = 74/212 (34%), Gaps = 35/212 (16%)

Query: 547 TIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGA 606
           TIP       S +     ++P      PTT  P   T         P+ KPS        
Sbjct: 634 TIPSEKPTIPSEKPTISTEKPTVPTEEPTT--PTEETTTSMEEPVIPTEKPS-------- 683

Query: 607 GPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWS 666
             IP + P IP + PT+     ++        E+   SPE P++   P    ++P+   S
Sbjct: 684 --IPTEKPSIPTEKPTISMEETIIST------EKPTISPEKPTI---PTEKPTIPTEK-S 731

Query: 667 GQASVNPPLPGPKPSIPEEHRQAIPESEAEDQER------------EPPSATVSPGQIPE 714
             +   P  P  KP+IP E     PE      E+            E P+       IP 
Sbjct: 732 TISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPT 791

Query: 715 SDPA-DLSPRDTPQGEDMLNAIRRGVKLKKTT 745
             P        TP  E  ++  +  + ++K T
Sbjct: 792 EKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 43/180 (23%), Positives = 68/180 (37%), Gaps = 26/180 (14%)

Query: 547 TIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRT-PSTKPSVRRGTIG 605
           TIP       + +    +++P   +  PT        P + T + T PS KP+       
Sbjct: 592 TIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEK---PTILTEKPTIPSEKPT------- 641

Query: 606 AGPIPIKTPVIPVKTPTVPDLPGVLPAP--------PDGPEERGEHSPESPSVGEGPQGV 657
              IP + P I  + PTVP      P          P  P E+     E PS+      +
Sbjct: 642 ---IPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTI 698

Query: 658 TSMPSSMWSGQASVNPP---LPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPE 714
           +   + + + + +++P    +P  KP+IP E     PE      E+ P   T  P   PE
Sbjct: 699 SMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK-PTIPTEKPTISPE 757



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 50/223 (22%), Positives = 82/223 (36%), Gaps = 52/223 (23%)

Query: 507  TQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMFQAKR 566
            T+  T    E T P++ +       S   E      ++++T    + IS     +   K 
Sbjct: 791  TEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKP 850

Query: 567  PASTAG--LPT---TLGPAMVTPGVATIRRT-PSTKPSV--RRGTIGAGPIPIKT----- 613
              ST    +PT   T+ P  +T  + T + T P+ KP++     TI    + I T     
Sbjct: 851  TISTEKPTIPTEKPTISPEKLT--IPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTI 908

Query: 614  -----------PVIPVKTPTVP---------------DLPGVLPAPPDGPEERGEHSPES 647
                       P IP + PT+P               + P + P     P E+   S E 
Sbjct: 909  SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEK 968

Query: 648  PSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAI 690
            P++   P    ++P+          P +P  KP+IP E   A+
Sbjct: 969  PTI---PTEKLTIPTE--------KPTIPTEKPTIPTEKLTAL 1000


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 48/167 (28%), Positives = 63/167 (37%), Gaps = 19/167 (11%)

Query: 567 PASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVPDL 626
           P      P T  P      +AT    P   P++    +   P P   P+ P+ TP  P  
Sbjct: 568 PLQAPPSPLTTPPPETPSSIAT--PPPQAPPALASPPLQGLPSP---PLSPLATPP-PQA 621

Query: 627 PGVLPAPP-DGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQAS--VNPPLPGP--KPS 681
           P  L  PP   P       P SP     PQ   ++   +     S   +PP+  P   P+
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681

Query: 682 IPEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPAD--LSPRDTP 726
            P     A P S+A      PPS    P Q+P S PA   +SP  TP
Sbjct: 682 SPPVSPSATPPSQA------PPSLAAPPLQVPPSPPASPPMSPSATP 722



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 79/342 (23%), Positives = 119/342 (34%), Gaps = 43/342 (12%)

Query: 402 PSSQIPSWKDWAKPGPYDQPLVNTLQRRKEKREPDPNGGGPTTASGPPAAAEEA------ 455
           PS  + +    A P P   P + TL          P    P + + PP  A  +      
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQTLP----SPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388

Query: 456 -QRPRSMTVSAATRPGEEMEACEELALALSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCC 514
            Q P S+T  +   P           LALS  LQ  T   S  +LQ +  + T +     
Sbjct: 389 IQVPHSLTSPSLQAPPSP--------LALS-SLQATTSLGS-PTLQATHSFLTMSPRQTQ 438

Query: 515 SEDTIPSQVSDYDYFSVSGDQEADQQEFDKSSTIPRNSDISQSYRRMFQAKRPASTAGLP 574
           +  T PS+ +     S   D    Q      ++ P  + +S +   +           L 
Sbjct: 439 ASLTSPSRPA-----STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493

Query: 575 TTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVPDLPGVLP--- 631
           +    +   P  + I     T+ S+        P  ++TP   + TP + +LP + P   
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSL-------APPSLQTPPASLTTPPLENLPSLAPPPL 546

Query: 632 ----APPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHR 687
               AP   P       P    +   P  +T+ P    S  A+  P  P    S P +  
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606

Query: 688 QAIPESE-AEDQEREPPSATVSPGQIPESDPAD--LSPRDTP 726
            + P S  A    + PP   + P Q P S PA   LSP  TP
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP 648



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 42/165 (25%), Positives = 65/165 (39%), Gaps = 22/165 (13%)

Query: 565 KRPASTAGLPTTLGPAM---VTPGVATIRRTPSTKPSVRRGTIGAGPIP-----IKTP-V 615
           +RP++  GL      ++    TP  +  R  PS + + R     + P P     ++ P V
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285

Query: 616 IPVKTPTVPDLPGVLPAP-----PDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQAS 670
            P +    P L  +  +P     P G + R    P++ +    P   T  PS   +    
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT---PLPATLPPSPPLATPLP 342

Query: 671 VNPPLPGPKPSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES 715
           + PP P   PS+     Q +P   A    + PPS T  P Q P S
Sbjct: 343 LAPPSPSAPPSL-----QTLPSPPATPPSQAPPSMTTPPMQAPPS 382



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 50/189 (26%), Positives = 69/189 (36%), Gaps = 20/189 (10%)

Query: 549 PRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGP 608
           P +  +S S     QA  P S A  P  + P+   P  +      +T P      + A P
Sbjct: 680 PASPPVSPSATPPSQA--PPSLAAPPLQVPPS---PPASPPMSPSATPPPQAPPPLAAPP 734

Query: 609 I------PIKTPVIPVKTPTVPDLPGVLPAPP-DGPEERGEHSPESPSVGEGPQGVTSMP 661
           +      P   P+ P  TP  P +P +L APP   P       P SP     PQ   ++ 
Sbjct: 735 LQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793

Query: 662 SSMWSGQASVNPPLPGPKPSIPEEHRQAIPESE-AEDQEREPPSATVSPGQIPESDPAD- 719
           +       S     PG  P  P     ++P S  A    + PP       Q+P S PA  
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPS---ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850

Query: 720 --LSPRDTP 726
              +PR  P
Sbjct: 851 TLQAPRRPP 859



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 40/158 (25%), Positives = 53/158 (33%), Gaps = 39/158 (24%)

Query: 574 PTTLGPAMVTPGVATIRRTPSTKPSVRRGTIGAGPIP--IKTPVIPVKTPTVPDLPGVLP 631
           P    PA+ TP +  +   P++ P       G  P       P+ P+ TP  P  P VL 
Sbjct: 785 PPQAPPALATPPLQALPSPPASFP-------GQAPFSPSASLPMSPLATPP-PQAPPVLA 836

Query: 632 AP----PDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEH- 686
           AP    P  P       P SP++                 QA   PP PGP  S+     
Sbjct: 837 APLLQVPPSP-------PASPTL-----------------QAPRRPPTPGPDTSVSGPRL 872

Query: 687 RQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRD 724
             A+         R P S    P     S  A  +P +
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 35/134 (26%), Positives = 49/134 (36%), Gaps = 9/134 (6%)

Query: 627 PGVL-PAPPDGPEERGEHSPESPSVGEGPQGVTSMPSSMWSGQAS-----VNPPLPGPKP 680
           PG+L P PP  P      +P +  V      V   P +  +G         + P  GP  
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 681 SIPEEHRQAIPESEAEDQ-EREPPSATVSPGQIPESDPADLSPRDTPQGED--MLNAIRR 737
           S     R       A  + ER PP+   SPG +     A  + R  P G+    ++A   
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141

Query: 738 GVKLKKTTTNDRSA 751
             + K T    RSA
Sbjct: 142 VARGKATEAPKRSA 155


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 70/305 (22%), Positives = 103/305 (33%), Gaps = 33/305 (10%)

Query: 423 VNTLQRRKEKREPDPNGGGPTTASGPPAAAEEAQRPRSMTVSAATRPGEEMEACEELALA 482
           V T   RK      P G  P  A G    AE++    S   S +      +      A +
Sbjct: 661 VGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS---SSEESDSEEEKTGLAVTVGQAKS 717

Query: 483 LSRGLQLDTQRSSRDSLQCSSGYSTQTTTPCCSEDTIPSQVSDYDYFSVSGDQEADQQEF 542
           + +GLQ+   +++   ++ S G  T    P  +  T+    ++    S S ++E+D +E 
Sbjct: 718 VGKGLQV---KAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEA 774

Query: 543 DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRRTPSTKPSVRRG 602
             S    + S      +    A R  S  G  +  G  +     A  R     KP VR  
Sbjct: 775 AASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRN- 833

Query: 603 TIGAGPIPIKTPVI---PVKTPTVPDLPGVLPAPPDGPEE-RGEHSPESPSVGEG----- 653
                  P  + V+   P   P+V            GPEE  G    ES S  E      
Sbjct: 834 -------PQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQ 886

Query: 654 --PQGVTSM--------PSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQEREPP 703
             P G T            S   G A   P   GP  +   +   +   SE  D + E P
Sbjct: 887 VKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 946

Query: 704 SATVS 708
           +A  S
Sbjct: 947 AAVTS 951



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 43/172 (25%), Positives = 63/172 (36%), Gaps = 29/172 (16%)

Query: 568 ASTAGLPTTLGPAMVTPGVATIRRTPSTK--PSVRRGTIGAGPIPIKTPV-IPVKTPTVP 624
           A +   P  +  A   P +    + P TK  P     T  A   P++     P K  T  
Sbjct: 618 ADSEEAPAAMTAAQAKPAL----KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTAT 673

Query: 625 DLPGVLPAPPDGPEERGEHSPESP-------------------SVGEGPQ-GVTSMPSSM 664
              G  PA   G +   E S  S                    SVG+G Q    S+P   
Sbjct: 674 SPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKG 733

Query: 665 WSGQASVNPPLPGPK-PSIPEEHRQAIPESEAEDQEREPPSATVSPGQIPES 715
             GQ +  P LPG   P++ +   +   +SE+ ++E +   A  SP Q+  S
Sbjct: 734 SLGQGTA-PVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTS 784


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 95/374 (25%), Positives = 128/374 (34%), Gaps = 86/374 (22%)

Query: 435  PDPNGGGPT---TASGP-------PAAAEEAQRPRSMTVSAATRPGEEMEACEELALALS 484
            P PN G P    T++GP         +      PR    S   + G+   A   +    +
Sbjct: 671  PGPNMGQPQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQT 730

Query: 485  RGLQLDTQRSSRDSLQCSSGYSTQTTTPC-----CSEDTIPSQ---VSDYDYFSVSGDQE 536
              LQ   Q +   +L    GY  +   P        +   PSQ   V++      SG   
Sbjct: 731  PPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAP 790

Query: 537  ADQQEFDKSSTIPRNSDISQ-----SYRRMFQAKRPASTAGLPTTLGPAMVTPGVATIRR 591
              Q +   SS+ P NS I       S+    Q  +PA     P+ +     TP       
Sbjct: 791  VSQAQMS-SSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPH------ 843

Query: 592  TPSTKPSVRRGTIGAGPIPIKTPVIPVKTPTVPDLPGVLPAPPDGPEERGEHSP----ES 647
               T PS     IGA   P  T   PV TP         PA P GP+ +  H P     +
Sbjct: 844  --HTPPS-----IGAQQPPATTIPAPVPTP---------PAMPPGPQSQALHPPPRQTPT 887

Query: 648  PSVGEGPQGV-------------TSMPSSMWSGQASV---NPPLPGPKPSIPEEHRQAIP 691
            P   + PQ V                P S  S  ASV     PL  P+P+ P       P
Sbjct: 888  PPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAASVPTPTAPLLPPQPATPLSQ----P 943

Query: 692  ESEAEDQEREPPSAT---VSPGQIPESDPA------------DLSPRDTPQGEDMLNAIR 736
                E Q   PPS +   V+   I E  P+               P DT Q ED+  +  
Sbjct: 944  AVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADT-QPEDISESKV 1002

Query: 737  RGVKLKKTTTNDRS 750
               K++ T T +RS
Sbjct: 1003 EDCKMESTETEERS 1016



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 6/105 (5%)

Query: 600  RRGTIGAGP-IPIKTPVIPV----KTPTVPDLPGVLPAP-PDGPEERGEHSPESPSVGEG 653
            R G +G    +P  TP  P     + PT P  P     P P  P     + P + + G  
Sbjct: 1837 RTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPV 1896

Query: 654  PQGVTSMPSSMWSGQASVNPPLPGPKPSIPEEHRQAIPESEAEDQ 698
             QG  +   +  +   +  PPLPGP P+  E   Q    +E + Q
Sbjct: 1897 SQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQ 1941



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 53/229 (23%), Positives = 78/229 (34%), Gaps = 51/229 (22%)

Query: 543 DKSSTIPRNSDISQSYRRMFQAKRPASTAGLPTTL--GPAMVTPGVATIRRTPSTKPSVR 600
           +K   I +  +  +  R   Q   P +   +P ++  GP M  P        P   PS+ 
Sbjct: 635 EKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMI 694

Query: 601 RGTIGAGPIPIKTP----------------VIPVKTPTVPD-----LPGVLPAPPDG--- 636
           RG++    +P  TP                ++P +TP +        PG L  PP G   
Sbjct: 695 RGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHGQLAQPGALN-PPMGYGP 753

Query: 637 ----PEERGEHSPES---------------PSVGEGPQGVTSMPSSMWSGQASVNPPLPG 677
               P  +G+  P++               PS G+ P     M SS       VN P+  
Sbjct: 754 RMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSS----SCPVNSPIMP 809

Query: 678 PKPSIPEEHRQAIPESEAEDQEREP-PSATVSPGQIPESDPADLSPRDT 725
           P       H   +P+         P PS T +P   P S  A   P  T
Sbjct: 810 PGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATT 858


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,183,184
Number of Sequences: 37866
Number of extensions: 2017182
Number of successful extensions: 14656
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 1017
Number of HSP's that attempted gapping in prelim test: 11002
Number of HSP's gapped (non-prelim): 3920
length of query: 755
length of database: 18,247,518
effective HSP length: 110
effective length of query: 645
effective length of database: 14,082,258
effective search space: 9083056410
effective search space used: 9083056410
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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