Guide to the Human Genome
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Search of human proteins with 9789865

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9789865 eukaryotic translation initiation factor 4E nuclear
import factor 1 [Homo sapiens]
         (985 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9789865 eukaryotic translation initiation factor 4E nuclear i...  1960   0.0  
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         49   2e-05
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    44   6e-04
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                44   6e-04
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    44   7e-04
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    44   7e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   0.001
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   0.001
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    44   0.001
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    44   0.001
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]            43   0.001
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ...    43   0.002
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ...    43   0.002
gi|221139926 NHS-like 1 [Homo sapiens]                                 42   0.002
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa...    42   0.002
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    42   0.002
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       42   0.003
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   42   0.004
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   42   0.004
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   42   0.004
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    42   0.004
gi|117938768 GNAS complex locus alex [Homo sapiens]                    42   0.004
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        42   0.004
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       40   0.008
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             40   0.011
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 40   0.011
gi|151301154 mucin 6, gastric [Homo sapiens]                           40   0.014
gi|148612879 polyhomeotic like 3 [Homo sapiens]                        39   0.018
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]      39   0.018
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         39   0.018

>gi|9789865 eukaryotic translation initiation factor 4E nuclear
           import factor 1 [Homo sapiens]
          Length = 985

 Score = 1960 bits (5078), Expect = 0.0
 Identities = 985/985 (100%), Positives = 985/985 (100%)

Query: 1   MDRRSMGETESGDAFLDLKKPPASKCPHRYTKEELLDIKELPHSKQRPSCLSEKYDSDGV 60
           MDRRSMGETESGDAFLDLKKPPASKCPHRYTKEELLDIKELPHSKQRPSCLSEKYDSDGV
Sbjct: 1   MDRRSMGETESGDAFLDLKKPPASKCPHRYTKEELLDIKELPHSKQRPSCLSEKYDSDGV 60

Query: 61  WDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERVKEDDLDVVFSPQRRS 120
           WDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERVKEDDLDVVFSPQRRS
Sbjct: 61  WDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERVKEDDLDVVFSPQRRS 120

Query: 121 FGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDL 180
           FGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDL
Sbjct: 121 FGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDL 180

Query: 181 RDRDRERDFKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDD 240
           RDRDRERDFKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDD
Sbjct: 181 RDRDRERDFKDKRFRREFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDD 240

Query: 241 KILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEPAADQEVPRDAVLPEQ 300
           KILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEPAADQEVPRDAVLPEQ
Sbjct: 241 KILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEPAADQEVPRDAVLPEQ 300

Query: 301 SPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHE 360
           SPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHE
Sbjct: 301 SPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHE 360

Query: 361 ELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANK 420
           ELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANK
Sbjct: 361 ELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANK 420

Query: 421 EKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGD 480
           EKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGD
Sbjct: 421 EKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGD 480

Query: 481 MTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPAS 540
           MTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPAS
Sbjct: 481 MTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPAS 540

Query: 541 SNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLG 600
           SNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLG
Sbjct: 541 SNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLG 600

Query: 601 DPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGF 660
           DPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGF
Sbjct: 601 DPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGF 660

Query: 661 RNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGK 720
           RNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGK
Sbjct: 661 RNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGK 720

Query: 721 AALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKE 780
           AALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKE
Sbjct: 721 AALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKE 780

Query: 781 QDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVH 840
           QDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVH
Sbjct: 781 QDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVH 840

Query: 841 PQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQ 900
           PQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQ
Sbjct: 841 PQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQ 900

Query: 901 QLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLAKWFG 960
           QLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLAKWFG
Sbjct: 901 QLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLAKWFG 960

Query: 961 SDVLQQPLPSMPAKVISVDELEYRQ 985
           SDVLQQPLPSMPAKVISVDELEYRQ
Sbjct: 961 SDVLQQPLPSMPAKVISVDELEYRQ 985


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 79/339 (23%), Positives = 133/339 (39%), Gaps = 47/339 (13%)

Query: 496  TLPS---QPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLE 552
            T+P+   +PK +R  E         PG+     +L +L  + V  P S      L+   +
Sbjct: 2429 TMPATRPKPKKARAAEESGAKGPRRPGEEA--ELLVKLDHEGVTSPKSKKAKEALLLRED 2486

Query: 553  PTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSP------IGFTPGPQQLLGDPFQGM 606
            P     G + P   LS      AA +    P+ P P      +   PGP    G  F+  
Sbjct: 2487 PGAG--GWQEPKSLLSLGSYPPAAGSS--EPKAPWPKATDGDLAQEPGP----GLTFEDS 2538

Query: 607  RKPMSPITAQMSQ--LELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGF---- 660
              P SP  AQ  Q   E  +++    +     +  +++      G+ + D+  DG     
Sbjct: 2539 GNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTG 2598

Query: 661  -RNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASG 719
             RN     +++ +P    +SSS + ++S +S  S              S   S    +S 
Sbjct: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSS-------------SSSSSSSSSSSSS 2645

Query: 720  KAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTK 779
             ++   S   +  +S  +  SSSS  + D DSS +++ + +    +  S   +   + TK
Sbjct: 2646 SSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATK 2705

Query: 780  EQ-DYRPKA--TGRKTPTLASPVPTTPFLRPVHQVPLVP 815
            +    RP A   G+KTP   +P P  P  +P    PL P
Sbjct: 2706 QAGKARPSAHSPGKKTP---APQPQAPPPQPTQ--PLQP 2739



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 5/136 (3%)

Query: 680  SSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPA--SGKAALGDSKEDTQKASEEN 737
            ++P P A      SP     +V +     K +  +EP   +G  A  D     +++    
Sbjct: 1944 AAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIF 2003

Query: 738  LLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKT-PTLA 796
            L  +S+   A   ++P T  K S   +    +P   A R    +D R K  G++  P   
Sbjct: 2004 LHDASAAAPAPVSTAPAT--KTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAG 2061

Query: 797  SPVPTTPFLRPVHQVP 812
             P P  P L    + P
Sbjct: 2062 LPPPRAPALPSEARAP 2077


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 99/399 (24%), Positives = 141/399 (35%), Gaps = 75/399 (18%)

Query: 572 QTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQ---LELQQA--A 626
           Q++ A A      +   +   P    +L  P  G+ +P +P  A       L +Q A  A
Sbjct: 569 QSQPAPAGPAATTVLQGVTLPPSAVAMLNTP-DGLVQPATPAAATGEAAPVLTVQPAPQA 627

Query: 627 LEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAA 686
              ++ P  L +Q     QP    PQ    +       Q  T  P+P   G +SSP    
Sbjct: 628 PPAVSTPLPLGLQQPQAQQP----PQAPTPQAAAP--PQATTPQPSP---GLASSPE--- 675

Query: 687 SITSMLSPSFTPTSVIRK----MYESKEKSKEE----------PASGKAALGDSKEDTQK 732
            I     PS TPT+++ +    M+  +E+S++           PAS   +     +D   
Sbjct: 676 KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAP 735

Query: 733 ASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKT 792
           A+     +     + D  +SP    ++ A        P S  +          +A    +
Sbjct: 736 ATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPS-------LPHQAPLGDS 788

Query: 793 PTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLL---- 848
           P L SP PT P  RP  +   V   P   P H   P            P  LP +     
Sbjct: 789 PHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQA---------PPTLPGIFVIQN 839

Query: 849 QTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLH 908
           Q GV PP  +       + P  G P  PL   S P   P P  P HL             
Sbjct: 840 QLGVPPPASN----PAPTAP--GPPQPPLRPQSQPPEGPLPPAP-HL------------- 879

Query: 909 PPGSGSHAAAVSVQTT---PQNVPSRSGLPHMHSQLEHR 944
           PP S S A A S +T+   P   PS   L    SQ  H+
Sbjct: 880 PPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHK 918


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 81/344 (23%), Positives = 125/344 (36%), Gaps = 55/344 (15%)

Query: 661  RNRQQRVTKSPAPVHRGNSSSPAPAAS-------ITSMLSPSFTPTSVIRKMYESKEKSK 713
            R R+  VTK P P   G  SSP+P A+       I+S L     P S +R+      +  
Sbjct: 1600 RGREPAVTKDPGP-GGGRDSSPSPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLD 1658

Query: 714  EEPASGKAALGDSKEDTQKASEENLLSSSSV--------------PSADRDSSPTTNSKL 759
            E PA G    G+    + +AS+ + +   ++               +A R++S  ++S L
Sbjct: 1659 ERPAEGSRERGEEAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSIL 1718

Query: 760  SALQRSSCSTPLS-QANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVP 818
            S +   S  + L    +R  ++ +    +  R     A+ V T+   R     P  P  P
Sbjct: 1719 SFVSGLSVGSTLQPPKHRKGRQAEGEMGSARRPEKRGAASVKTSGSPRS----PAGPEKP 1774

Query: 819  MVRPAHQLHPGLVQRMLAQGV--HPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYP 876
              R   +  PG+   +  + V   P   P     G   P    +  + ++ P L QP  P
Sbjct: 1775 --RGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGP---RATPRKVAPPCLAQPAAP 1829

Query: 877  LPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPH 936
                      P PG         QQ  RS LH P   S  A +S        P+R     
Sbjct: 1830 AKV-------PSPG---------QQRSRS-LHRPAKTSELATLSQPPRSATPPARLAKTP 1872

Query: 937  MHSQLEHRPSQ----RSSSPVGLAKWFGSDVLQQPLPSMPAKVI 976
              S  +  P+     R   PV  A          P+P  PA+ +
Sbjct: 1873 SSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTL 1916


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 53/226 (23%), Positives = 85/226 (37%), Gaps = 24/226 (10%)

Query: 710  EKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCST 769
            E +++      A + D  ++  +   +N L SSS  S    S+PTT +  ++L     +T
Sbjct: 1780 ESTRQATQLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTT 1839

Query: 770  PLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQV-PLVP-HVPMVRPAHQLH 827
                +   T        AT    P ++S         PV+ V P  P  +P+  P  Q  
Sbjct: 1840 VALSSTSQT--------ATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFA 1891

Query: 828  PGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNP 887
              L+     Q + P  LP     G  PP       Q   GP   +P  P  A +    +P
Sbjct: 1892 HALLAAQTFQQIRPPRLPMTHFGGTFPPA------QSTWGPFPVRPLSPARATN----SP 1941

Query: 888  RPG-TPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRS 932
            +P   P H     Q    S ++  GS + +   +  ++   VP  S
Sbjct: 1942 KPHMVPRH---SNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTS 1984



 Score = 37.4 bits (85), Expect = 0.070
 Identities = 94/450 (20%), Positives = 161/450 (35%), Gaps = 65/450 (14%)

Query: 523  PKNILQELLGQPVQRPASSNLLSGLMGSLEPTT-----SLLGQRAPSPPLSQVFQTRAA- 576
            P   + EL+ +   + +S+N     +GS  PTT     SL+G +  +  LS   QT  A 
Sbjct: 1796 PDKEIDELIPKNRLKSSSAN---SKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATAL 1852

Query: 577  ----------------SADYLRPRIPSPIGFTPGPQQ-----LLGDPFQGMRKPMSPITA 615
                              + +RP  P  +     P Q     L    FQ +R P  P+T 
Sbjct: 1853 TVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTH 1912

Query: 616  QMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFR-NRQQRVTKSPAPV 674
                    Q+      +      +A N  +P       ++   G + N    +T SP   
Sbjct: 1913 FGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTT 1972

Query: 675  HRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKAS 734
               +S+S  P  S     SPS    SV R+++ +  K+     +       +       +
Sbjct: 1973 -TSSSASTVPGTSTNG--SPS--SPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNA 2027

Query: 735  EENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPT 794
               + ++         SSP+  ++   + R+S   PL   +    +      A+  +   
Sbjct: 2028 TYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNS---PLDCGSASPNKV-----ASSSEQEA 2079

Query: 795  LASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLP 854
             + PV  T   RP       P+      +   H    Q+     V  +  P L Q+ V P
Sbjct: 2080 GSPPVVETTNTRP-------PNSSSSSGSSSAHSN--QQQPPGSVSQEPRPPLQQSQVPP 2130

Query: 855  PG--MDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGS 912
            P   M +  L   S P+       +P+ + P+  P P TP+       +++   + PP  
Sbjct: 2131 PEVRMTVPPLATSSAPVA------VPSTA-PVTYPMPQTPMGCPQPTPKMETPAIRPPPH 2183

Query: 913  GS---HAAAVSVQTTPQNVPSRSGLPHMHS 939
            G+   H  + SVQ +   V S + +   HS
Sbjct: 2184 GTTAPHKNSASVQNSSVAVLSVNHIKRPHS 2213


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 53/226 (23%), Positives = 85/226 (37%), Gaps = 24/226 (10%)

Query: 710  EKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCST 769
            E +++      A + D  ++  +   +N L SSS  S    S+PTT +  ++L     +T
Sbjct: 1529 ESTRQATQLINALIKDPDKEIDELIPKNRLKSSSANSKIGSSAPTTTAANTSLMGIKMTT 1588

Query: 770  PLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQV-PLVP-HVPMVRPAHQLH 827
                +   T        AT    P ++S         PV+ V P  P  +P+  P  Q  
Sbjct: 1589 VALSSTSQT--------ATALTVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFA 1640

Query: 828  PGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNP 887
              L+     Q + P  LP     G  PP       Q   GP   +P  P  A +    +P
Sbjct: 1641 HALLAAQTFQQIRPPRLPMTHFGGTFPPA------QSTWGPFPVRPLSPARATN----SP 1690

Query: 888  RPG-TPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRS 932
            +P   P H     Q    S ++  GS + +   +  ++   VP  S
Sbjct: 1691 KPHMVPRH---SNQNSSGSQVNSAGSLTSSPTTTTSSSASTVPGTS 1733



 Score = 37.4 bits (85), Expect = 0.070
 Identities = 94/450 (20%), Positives = 161/450 (35%), Gaps = 65/450 (14%)

Query: 523  PKNILQELLGQPVQRPASSNLLSGLMGSLEPTT-----SLLGQRAPSPPLSQVFQTRAA- 576
            P   + EL+ +   + +S+N     +GS  PTT     SL+G +  +  LS   QT  A 
Sbjct: 1545 PDKEIDELIPKNRLKSSSAN---SKIGSSAPTTTAANTSLMGIKMTTVALSSTSQTATAL 1601

Query: 577  ----------------SADYLRPRIPSPIGFTPGPQQ-----LLGDPFQGMRKPMSPITA 615
                              + +RP  P  +     P Q     L    FQ +R P  P+T 
Sbjct: 1602 TVPAISSASTHKTIKNPVNNVRPGFPVSLPLAYPPPQFAHALLAAQTFQQIRPPRLPMTH 1661

Query: 616  QMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFR-NRQQRVTKSPAPV 674
                    Q+      +      +A N  +P       ++   G + N    +T SP   
Sbjct: 1662 FGGTFPPAQSTWGPFPVRPLSPARATNSPKPHMVPRHSNQNSSGSQVNSAGSLTSSPTTT 1721

Query: 675  HRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKAS 734
               +S+S  P  S     SPS    SV R+++ +  K+     +       +       +
Sbjct: 1722 -TSSSASTVPGTSTNG--SPS--SPSVRRQLFVTVVKTSNATTTTVTTTASNNNTAPTNA 1776

Query: 735  EENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPT 794
               + ++         SSP+  ++   + R+S   PL   +    +      A+  +   
Sbjct: 1777 TYPMPTAKEHYPVSSPSSPSPPAQPGGVSRNS---PLDCGSASPNKV-----ASSSEQEA 1828

Query: 795  LASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLP 854
             + PV  T   RP       P+      +   H    Q+     V  +  P L Q+ V P
Sbjct: 1829 GSPPVVETTNTRP-------PNSSSSSGSSSAHSN--QQQPPGSVSQEPRPPLQQSQVPP 1879

Query: 855  PG--MDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGS 912
            P   M +  L   S P+       +P+ + P+  P P TP+       +++   + PP  
Sbjct: 1880 PEVRMTVPPLATSSAPVA------VPSTA-PVTYPMPQTPMGCPQPTPKMETPAIRPPPH 1932

Query: 913  GS---HAAAVSVQTTPQNVPSRSGLPHMHS 939
            G+   H  + SVQ +   V S + +   HS
Sbjct: 1933 GTTAPHKNSASVQNSSVAVLSVNHIKRPHS 1962


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 75/302 (24%), Positives = 98/302 (32%), Gaps = 28/302 (9%)

Query: 671 PAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDT 730
           PAP  R    +  P  S++S    S T  S   +   S     + PAS   +   +   +
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 731 QKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGR 790
              S     S+   P A    S      L AL+    + P   A          P AT  
Sbjct: 252 PARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 791 KTPTLASPVPTTPFLRP---------VHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHP 841
            +  L S  P T    P            +PL P  P   P+ Q  P       +Q    
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368

Query: 842 QHLPSLLQTGVLPPGMDLSHLQ--------GISGPILGQPFYPLPAAS---HPLLNPRPG 890
              P+L  T    P   LS L          ++ P L  P  P P AS    PL  P P 
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP--PSPPASPPLSPLATPSPQ 426

Query: 891 TPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSS 950
            P  LA+    L ++   PP S    A  S   +P   PS +        L   P Q   
Sbjct: 427 APNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483

Query: 951 SP 952
           SP
Sbjct: 484 SP 485



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 109/419 (26%), Positives = 136/419 (32%), Gaps = 83/419 (19%)

Query: 520 QPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTTSLLG----QRAPSPPLS------- 568
           +P P    +   G  +QRPAS +L S       P  S        RAP+ P         
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 569 -----QVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQ 623
                QV   R  +A  L P   SP+  TP P   L    Q    P  P T   S L  Q
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLA-TPSPSAAL----QSQAPPTLPATPHSSSLTCQ 333

Query: 624 QAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAP-VHRGNSSSP 682
            A    LA P   A  +          P             Q  T   +P +   +S  P
Sbjct: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPP-----------SQATTSLGSPTLQATHSFLP 382

Query: 683 APAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSS 742
           +P  S  +   P   P   +  +        + P S  A+   S   T      N L   
Sbjct: 383 SPPLSPLATPPPQAPPALALPPL--------QAPPSPPASPPLSPLATPSPQAPNAL--- 431

Query: 743 SVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKAT--GRKTPTLASP-- 798
           +V       SP  +  + A      S P+S            P AT   +  P+LA+P  
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVS------------PSATPPSQAPPSLAAPPL 479

Query: 799 -VPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGM 857
            VP +P   P       P  P   P  Q  P L    L     P   P  L T   PP  
Sbjct: 480 QVPPSPPASP-------PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT---PP-- 527

Query: 858 DLSHLQGISGPILGQ-PFYP---LPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGS 912
            L  L        GQ PF P   LP +  PL  P P  P  LA    Q+  S   PP S
Sbjct: 528 -LQALPSPPASFPGQAPFSPSASLPMS--PLATPPPQAPPVLAAPLLQVPPS---PPAS 580


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 112/475 (23%), Positives = 154/475 (32%), Gaps = 53/475 (11%)

Query: 498 PSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLE-PTTS 556
           PSQPK  + L++ L  P   P +      L  L   P+  P+ S   +  +   +   T 
Sbjct: 269 PSQPK-PKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326

Query: 557 LLGQRAPSPPLSQVFQTR--AASADYLRPRIPSPIGFTPG--PQQLLGDPFQGMRKPMSP 612
           L     PSPPL+        + SA      +PSP    P   P  +   P Q    P S 
Sbjct: 327 LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA---PPSL 383

Query: 613 ITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGF----RNRQQRVT 668
            T    Q+     +    A P  LA+ +        G P +  T        R  Q  +T
Sbjct: 384 QTIPPIQVPHSLTSPSLQAPPSPLALSSLQA-TTSLGSPTLQATHSFLTMSPRQTQASLT 442

Query: 669 KSPAPVHRGNSSSPAPAA-------SITSMLSPSFTPTS---VIRKMYESKEKSKEEPAS 718
               P      S P  A         + + LSP+ +P S    I  +      +   P +
Sbjct: 443 SPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502

Query: 719 GKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYT 778
             ++L     +TQ        SS + PS     +  T   L  L  S    PL  A+   
Sbjct: 503 PLSSLIMPPLETQ--------SSLAPPSLQTPPASLTTPPLENLP-SLAPPPLQTASA-- 551

Query: 779 KEQDYRPKATGR-KTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQ 837
                 P  T   +TP   +P P      P+   P      +  P  Q  P L    L  
Sbjct: 552 ------PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605

Query: 838 GVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAM 897
              P   P        PP + L  LQ    P    P         PL  P P  P  LA+
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL-------SPLATPSPQAPNALAV 658

Query: 898 VQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSP 952
               L ++   PP S    A  S   +P   PS +        L   P Q   SP
Sbjct: 659 ---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 111/456 (24%), Positives = 157/456 (34%), Gaps = 54/456 (11%)

Query: 520 QPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTTSLLGQR----APSPPLS------- 568
           +P P    +   G  +QRPAS +L S       P  S    R    AP+ P         
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278

Query: 569 -----QVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQ 623
                QV   R  +A  L P   SP+  TP P      P        +P+ A +      
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLA-TPSPSGTKARPVPPPDNAATPLPATLPPSP-- 335

Query: 624 QAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPA 683
                 LA P  LA  + +        P    T       Q   + +  P+    S    
Sbjct: 336 -----PLATPLPLAPPSPSAPPSLQTLPSPPATPPS----QAPPSMTTPPMQAPPSLQTI 386

Query: 684 PAASIT-SMLSPSF-TPTSVIRKMYESKEKSKEEPA--SGKAALGDSKEDTQKASEENLL 739
           P   +  S+ SPS   P S +         S   P   +  + L  S   TQ +     L
Sbjct: 387 PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS-----L 441

Query: 740 SSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQA-NRYTKEQDYRPKATGRKTPTLASP 798
           +S S P++    SP   + LS        T LS A +  +      P    +   +LAS 
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL---QALSSLASH 498

Query: 799 VPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMD 858
            P  P L  +   PL     +  P+ Q  P  +     + + P   P  LQT   P  + 
Sbjct: 499 SPQAP-LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL-PSLAPPPLQTASAP--LT 554

Query: 859 LSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAA 918
             HL+    P       PL A   PL  P P TP  +A    Q   ++  PP  G  +  
Sbjct: 555 TPHLETPPCPAP----CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610

Query: 919 VS-VQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPV 953
           +S + T P   P    LP     L+  PS  +S P+
Sbjct: 611 LSPLATPPPQAPPXLALP----PLQAPPSPPASPPL 642



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 109/517 (21%), Positives = 160/517 (30%), Gaps = 80/517 (15%)

Query: 496 TLPSQPKVSRNLESHLMSPAEIPGQPV-----PKNILQELLGQPVQRPASSNLLSGLMGS 550
           TLPS P    +     M+   +   P      P  +   L    +Q P S   LS L  +
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQAT 415

Query: 551 -------LEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPF 603
                  L+ T S L         S    +R AS     P + +P+     P      P 
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP------PL 469

Query: 604 QGMRKP-MSPITAQMSQLELQ----------QAALEGLALPHDLAVQAANFYQPGFGKPQ 652
           Q    P +SP+++ ++   LQ          QA L  L +P  L  Q++    P    P 
Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP-PLETQSS-LAPPSLQTPP 527

Query: 653 VDRTRDGFRNRQQRVTKSPAPVHRGNSS------------SPAPAASITSMLS--PSFTP 698
              T     N     + +P P+   ++             +P P  +  S L+  P  TP
Sbjct: 528 ASLTTPPLENLP---SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584

Query: 699 TSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSK 758
           +S+     ++       P  G  +   S   T        L+   +P      SP  +  
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA---LPPLQAPPSPPASPP 641

Query: 759 LSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVP 818
           LS L   S   P + A    +                 SP P+ P   P       P  P
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAP--------------FSPPPSPPVQAPFSPPASPPVSP 687

Query: 819 MVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLP 878
              P  Q  P L    L     P   P +  +   PP         ++ P L  P  P P
Sbjct: 688 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP----PPLAAPPLQVP--PSP 741

Query: 879 AASHPL---LNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLP 935
            AS P+     P P  P  LA    Q+      PP   +      +   P   P     P
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQV------PPSPPASLPMSPLAKPPPQAPPALATP 795

Query: 936 HMHSQLEHRPSQRSSSPVGLAKWFGSDVLQQPLPSMP 972
            + +      S    +P   +       L  P P  P
Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 832



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 90/434 (20%), Positives = 141/434 (32%), Gaps = 112/434 (25%)

Query: 583 PRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAAN 642
           PR P P+  TP   ++LG      RKP++           +   + G  +P         
Sbjct: 33  PRPPPPV--TPAALRVLGAAGAVGRKPLAE----------RAGGIGGATIPESA------ 74

Query: 643 FYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVI 702
                   P+   TR    + +   ++ PA   RG  + PA   S   + SP        
Sbjct: 75  --------PRAGPTRSAGTSSRNPASRPPAS-GRGERAPPAKNTSPGPVSSPG------- 118

Query: 703 RKMYESKEKSKEEPASGKAALGDSKEDTQ---KASEENLLSSSSVPSADRDSSPTTNSKL 759
                +   ++  P  G+  L  S E+T    KA+E    S+ S  +    S PT  +  
Sbjct: 119 ----RASGTTRPGPL-GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173

Query: 760 SALQRSSCST---------------------PLSQANRYTKEQDYRPKATGRKTPTLASP 798
            A+ R S +                      P    +  ++     P    R+ P+    
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233

Query: 799 VP----------TTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLL 848
           +            TP   P    P     P   PAH   P            P+ L +L 
Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRA-PAHPSQP-----------KPKGLQALR 281

Query: 849 QTGVLPPGMDLSHLQG--ISGPIL--------GQPFYPLPAASHPL---LNPRP--GTPL 893
              V PP  D +   G   S P+          +P  P   A+ PL   L P P   TPL
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 894 HLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPV 953
            LA            PP   +  +  ++ + P   PS++        ++  PS ++  P+
Sbjct: 342 PLA------------PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI 389

Query: 954 GLAKWFGSDVLQQP 967
            +     S  LQ P
Sbjct: 390 QVPHSLTSPSLQAP 403


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 73/274 (26%), Positives = 101/274 (36%), Gaps = 40/274 (14%)

Query: 664 QQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAAL 723
           Q  +T+S  P     SS P    S T  L+PS TPT                P+S     
Sbjct: 31  QPILTRSSTPTLTP-SSPPTLTPSNTPTLTPSNTPTLT--------------PSSTPTLT 75

Query: 724 GDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDY 783
             S   T   + + +L+ SS P+    S PT     +     S +  L+ +N  T     
Sbjct: 76  PSS---TPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS 132

Query: 784 RPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHV-PMVRPAHQLHPGLVQRMLAQGVHPQ 842
            P  T   TPTL      TP  RP+      P + P  RP       ++ R     + P 
Sbjct: 133 TPTLTPSSTPTL------TPSSRPILTRSSTPTLTPSSRP-------ILTRSSTPTLTPS 179

Query: 843 HLPSLL--QTGVLPPGMDLSHLQGISGPILGQPFYP-LPAASHPLLNPRPGTPLHLAMVQ 899
             P+L    T  L P      L   S PIL +   P L  +S P+L P   TP      +
Sbjct: 180 STPTLTPSSTPTLTPS-STPTLTPSSRPILTRSSTPTLTPSSRPILTP-SSTPTLTPSSR 237

Query: 900 QQLQRS---VLHPPGSGSHAAAVSVQTTPQNVPS 930
             L RS    L P  + +   + +   TP N P+
Sbjct: 238 PILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 1/118 (0%)

Query: 679 SSSPAPAASITSMLSPSFTPT-SVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEEN 737
           SS+P    S T  L+PS TPT +   +   ++  +     S +  L  S   T   S   
Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238

Query: 738 LLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTL 795
           +L+ SS P+    S+PT     +     S +  L+ +N  T      P  T   TPTL
Sbjct: 239 ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTL 296



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 59/210 (28%), Positives = 78/210 (37%), Gaps = 46/210 (21%)

Query: 692 LSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDS 751
           L+PS TPT                  S    L  S   T   S + +L+ SS P+    S
Sbjct: 2   LTPSNTPTLT---------------PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSS 46

Query: 752 SPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVP-----TTPFLR 806
            PT           S +  L+ +N  T      P  T   TPTL +P P     +TP L 
Sbjct: 47  PPTLT--------PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTL-TPQPILTRSSTPTLT 97

Query: 807 PVHQVPLVP-HVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLL--QTGVLPPGMDLSHLQ 863
           P     L P + P + P++   P L          P + P+L    T  L P      L 
Sbjct: 98  PSSPPTLTPSNTPTLTPSNT--PTLT---------PSNTPTLTPSSTPTLTPS-STPTLT 145

Query: 864 GISGPILGQPFYP-LPAASHPLLNPRPGTP 892
             S PIL +   P L  +S P+L  R  TP
Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILT-RSSTP 174


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 73/274 (26%), Positives = 101/274 (36%), Gaps = 40/274 (14%)

Query: 664 QQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAAL 723
           Q  +T+S  P     SS P    S T  L+PS TPT                P+S     
Sbjct: 31  QPILTRSSTPTLTP-SSPPTLTPSNTPTLTPSNTPTLT--------------PSSTPTLT 75

Query: 724 GDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDY 783
             S   T   + + +L+ SS P+    S PT     +     S +  L+ +N  T     
Sbjct: 76  PSS---TPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSS 132

Query: 784 RPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHV-PMVRPAHQLHPGLVQRMLAQGVHPQ 842
            P  T   TPTL      TP  RP+      P + P  RP       ++ R     + P 
Sbjct: 133 TPTLTPSSTPTL------TPSSRPILTRSSTPTLTPSSRP-------ILTRSSTPTLTPS 179

Query: 843 HLPSLL--QTGVLPPGMDLSHLQGISGPILGQPFYP-LPAASHPLLNPRPGTPLHLAMVQ 899
             P+L    T  L P      L   S PIL +   P L  +S P+L P   TP      +
Sbjct: 180 STPTLTPSSTPTLTPS-STPTLTPSSRPILTRSSTPTLTPSSRPILTP-SSTPTLTPSSR 237

Query: 900 QQLQRS---VLHPPGSGSHAAAVSVQTTPQNVPS 930
             L RS    L P  + +   + +   TP N P+
Sbjct: 238 PILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 1/118 (0%)

Query: 679 SSSPAPAASITSMLSPSFTPT-SVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEEN 737
           SS+P    S T  L+PS TPT +   +   ++  +     S +  L  S   T   S   
Sbjct: 179 SSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRP 238

Query: 738 LLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTL 795
           +L+ SS P+    S+PT     +     S +  L+ +N  T      P  T   TPTL
Sbjct: 239 ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTL 296



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 59/210 (28%), Positives = 78/210 (37%), Gaps = 46/210 (21%)

Query: 692 LSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDS 751
           L+PS TPT                  S    L  S   T   S + +L+ SS P+    S
Sbjct: 2   LTPSNTPTLT---------------PSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSS 46

Query: 752 SPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVP-----TTPFLR 806
            PT           S +  L+ +N  T      P  T   TPTL +P P     +TP L 
Sbjct: 47  PPTLT--------PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTL-TPQPILTRSSTPTLT 97

Query: 807 PVHQVPLVP-HVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLL--QTGVLPPGMDLSHLQ 863
           P     L P + P + P++   P L          P + P+L    T  L P      L 
Sbjct: 98  PSSPPTLTPSNTPTLTPSNT--PTLT---------PSNTPTLTPSSTPTLTPS-STPTLT 145

Query: 864 GISGPILGQPFYP-LPAASHPLLNPRPGTP 892
             S PIL +   P L  +S P+L  R  TP
Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILT-RSSTP 174


>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 280

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 43/152 (28%), Positives = 60/152 (39%), Gaps = 14/152 (9%)

Query: 679 SSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENL 738
           S++P    S T  L+PS TPT        +   +     S    L  S   T   S    
Sbjct: 89  SNTPTLTPSSTPTLTPSSTPTL-------TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPT 141

Query: 739 LSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLA-S 797
           L+ SS P+    S+PT     +     S +  L+ ++  T     RP  T   TPTL  S
Sbjct: 142 LTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPS 201

Query: 798 PVPT-----TPFLRPVHQVPLVP-HVPMVRPA 823
             PT     TP L P +   L+P   P + P+
Sbjct: 202 STPTLTPSSTPTLTPSNTPTLIPSSTPTLTPS 233



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 39/136 (28%), Positives = 55/136 (40%), Gaps = 12/136 (8%)

Query: 679 SSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENL 738
           SS+P    S T  L+PS TPT        +   +     S +  L  S   T   S    
Sbjct: 153 SSTPTLTPSSTPTLTPSSTPTL-------TPSSTPTLTPSSRPILTRSSTPTLTPSSTPT 205

Query: 739 LSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASP 798
           L+ SS P+    ++PT     +     S +  L+ ++R T  +   P  T   TPTL   
Sbjct: 206 LTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTP- 264

Query: 799 VPTTPFLRPV---HQV 811
             +TP L P    HQV
Sbjct: 265 -SSTPTLTPSSLWHQV 279



 Score = 31.6 bits (70), Expect = 3.8
 Identities = 54/197 (27%), Positives = 74/197 (37%), Gaps = 34/197 (17%)

Query: 739 LSSSSVPSADRDSSPTTNSKLSALQRSSCSTP-LSQANRYTKEQDYRPKATGRKTPTLAS 797
           L+ SS P+    ++PT  +  S    + CSTP L+ +N  T      P  T   TPTL  
Sbjct: 54  LTPSSPPTLTPSNTPTL-TPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTP 112

Query: 798 PVPTTPFLRPVHQVPLVP-HVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLL--QTGVLP 854
              +TP L P     L P   P + P+    P L  R     + P   P+L    T  L 
Sbjct: 113 --SSTPTLTPSSTPTLTPSSTPTLTPSST--PTLT-RSSTPTLTPSSTPTLTPSSTPTLT 167

Query: 855 PGMDLSHLQGISGPILGQPFYP-LPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSG 913
           P          S P L     P L  +S P+L  R  TP              L P  + 
Sbjct: 168 PS---------STPTLTPSSTPTLTPSSRPILT-RSSTP-------------TLTPSSTP 204

Query: 914 SHAAAVSVQTTPQNVPS 930
           +   + +   TP N P+
Sbjct: 205 TLTPSSTPTLTPSNTPT 221


>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
           sapiens]
          Length = 386

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 26/145 (17%)

Query: 817 VPMVRPAHQLHP-----GLVQRMLAQGVHPQHLPSLLQT----GVLPPGMDLSHLQGISG 867
           VP+V+P+H +HP            + G HP H+PS + +       PP  D+     +S 
Sbjct: 142 VPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSP 201

Query: 868 PILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQN 927
             +GQ   PL   SH ++   PG                 H  G   H A V+ Q   ++
Sbjct: 202 GGVGQITPPLGWFSHHMIPGPPGP----------------HTTGI-PHPAIVTPQVKQEH 244

Query: 928 VPSRSGLPHMHSQLEHRPSQRSSSP 952
             + S L H+  Q E R  Q    P
Sbjct: 245 PHTDSDLMHVKPQHEQRKEQEPKRP 269


>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
           sapiens]
          Length = 371

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 26/145 (17%)

Query: 817 VPMVRPAHQLHP-----GLVQRMLAQGVHPQHLPSLLQT----GVLPPGMDLSHLQGISG 867
           VP+V+P+H +HP            + G HP H+PS + +       PP  D+     +S 
Sbjct: 142 VPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSP 201

Query: 868 PILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQN 927
             +GQ   PL   SH ++   PG                 H  G   H A V+ Q   ++
Sbjct: 202 GGVGQITPPLGWFSHHMIPGPPGP----------------HTTGI-PHPAIVTPQVKQEH 244

Query: 928 VPSRSGLPHMHSQLEHRPSQRSSSP 952
             + S L H+  Q E R  Q    P
Sbjct: 245 PHTDSDLMHVKPQHEQRKEQEPKRP 269


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 75/304 (24%), Positives = 103/304 (33%), Gaps = 57/304 (18%)

Query: 670  SPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKED 729
            SP   HR    SP+   S  S    + TP  V  K           PA+GK   G  K  
Sbjct: 838  SPEKSHR--VISPSSGYSSQSNTPTALTPVPVFLKSVS--------PANGK---GKPKPK 884

Query: 730  TQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATG 789
              +  + +L+SS S+ S+    S +T+++ S   +                      A G
Sbjct: 885  VPER-KSSLISSVSISSSSTSLSSSTSTEGSGTMKKL------------------DPAVG 925

Query: 790  RKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQ 849
                    PVP+ PF  P  + P +P  P V    Q  P     +    V P   P  L 
Sbjct: 926  SPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSP-----LPHSPVFPPPPPEALI 980

Query: 850  TGVLPPGMDLSHLQGISGPIL--GQPFYPLPAASHPLLNPRPGTPLHLAMV--------- 898
                PP   LS  +    PIL       PLP    P   P P  PL    +         
Sbjct: 981  PFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTN 1040

Query: 899  --QQQLQRSVLHPPGSGSHAA--AVSVQTTP-----QNVPSRSGLPHMHSQLEHRPSQRS 949
              Q +  R  L PP +    +   + + TT      Q  P R       +QL  R +Q  
Sbjct: 1041 SGQPESSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQ 1100

Query: 950  SSPV 953
             +PV
Sbjct: 1101 RTPV 1104


>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
           sapiens]
          Length = 399

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 41/159 (25%), Positives = 62/159 (38%), Gaps = 26/159 (16%)

Query: 817 VPMVRPAHQLHP-----GLVQRMLAQGVHPQHLPSLLQT----GVLPPGMDLSHLQGIS- 866
           VP+V+P+H +HP            + G HP H+PS + +       PP  D+     +S 
Sbjct: 142 VPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSP 201

Query: 867 ---GPIL------GQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGS--- 914
              G I       GQP YP+         P P +      + +     +  PPG  +   
Sbjct: 202 GGVGQITPPLGWQGQPVYPITGG---FRQPYPSSLSVDTSMSRFSHHMIPGPPGPHTTGI 258

Query: 915 -HAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSP 952
            H A V+ Q   ++  + S L H+  Q E R  Q    P
Sbjct: 259 PHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRP 297


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 77/325 (23%), Positives = 116/325 (35%), Gaps = 37/325 (11%)

Query: 667 VTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDS 726
           V   P+ V    S  P+P + + S+LS   +P S +     S       P S    L D 
Sbjct: 156 VPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSPPSDV----PSPPSDVPSPPSDVPLLSDV 211

Query: 727 KEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPK 786
                  S+  LLS    P +D  S P+    LS +       P   +   +   D  P 
Sbjct: 212 PSPP---SDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPP 268

Query: 787 ATGRKTPTLASPVPTTP---------FLRPVHQVP-LVPHVPMVRPAHQLHPGLVQRMLA 836
           +     P+L S VP+ P            P   VP L+  VP         P  +  +  
Sbjct: 269 SD---VPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSG 325

Query: 837 QGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFY---PLPAASHP--LLNPRPGT 891
               P  +PS       PP  D+  L G+  P+   P     P P +  P  L++P    
Sbjct: 326 VPSPPSDVPSPPSDVPSPPS-DVPLLSGVPSPLSDVPLLSGVPSPPSDVPSLLMSPHRLL 384

Query: 892 PLHLAMVQQQ---LQRSVLHPPG--SGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPS 946
             H ++V      +   +   P   SG  ++   V + P  VP  SG+P + S +     
Sbjct: 385 MSHYSLVSPHRLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVP---- 440

Query: 947 QRSSSPVGLAKWFGSDVLQQPLPSM 971
             S S V +  W     L  PL ++
Sbjct: 441 --SPSGVPITLWCPLTTLWCPLSTL 463



 Score = 39.3 bits (90), Expect = 0.018
 Identities = 54/180 (30%), Positives = 71/180 (39%), Gaps = 38/180 (21%)

Query: 809 HQVPLVPHVPMVRPAH---QLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGI 865
           H   + PH P+V P H    LH  LV       V P H           P + L H    
Sbjct: 13  HYSVVSPHCPLVPPHHPLVSLHHPLVSPHFPL-VSPHH-----------PLVSLHH---- 56

Query: 866 SGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVS----- 920
             P+   P +PL +  HPL++P      H ++V  Q      H P    H + VS     
Sbjct: 57  --PV--SPHFPLVSPHHPLMSP------HYSLVSPQYSPVSPHCPLVSPHYSLVSPHRPL 106

Query: 921 VQTTPQNVPS-RSGLPHMHSQLEHRPSQRSSSPVGLAKWFGSDV--LQQPLPSMPAKVIS 977
           V      VPS  S +P + S +   PS  SS P  +     SDV  L   +PS P+ V S
Sbjct: 107 VSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLL-SDVPSLLSGVPSPPSDVPS 165



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 50/189 (26%), Positives = 73/189 (38%), Gaps = 23/189 (12%)

Query: 800 PTTPFLRPVHQV-----PLVPHVPMVRPAHQL---HPGLVQRMLAQGVHPQHLPSLLQTG 851
           P  P + P H +     P+ PH P+V P H L   H  LV         PQ+ P      
Sbjct: 40  PHFPLVSPHHPLVSLHHPVSPHFPLVSPHHPLMSPHYSLVS--------PQYSPVSPHCP 91

Query: 852 VLPPGMDL--SHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHP 909
           ++ P   L   H   +S  + G P  P    S  LL+  P  P  ++     +   +   
Sbjct: 92  LVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPS--LLSGVPSLPSDVSSPPSDVPSLLSDV 149

Query: 910 PG--SGSHAAAVSVQTTPQNVPS-RSGLPHMHSQLEHRPSQRSSSPVGLAKWFGSDVLQQ 966
           P   SG  +    V + P +VPS  S +P + S +   PS   S P  +        L  
Sbjct: 150 PSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLS 209

Query: 967 PLPSMPAKV 975
            +PS P+ V
Sbjct: 210 DVPSPPSDV 218



 Score = 37.7 bits (86), Expect = 0.053
 Identities = 69/266 (25%), Positives = 98/266 (36%), Gaps = 44/266 (16%)

Query: 742 SSVPSADRD-SSPTTN---------SKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRK 791
           S VPS   D SSP ++         S LS +       P   ++  +   D     +G  
Sbjct: 126 SGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVP 185

Query: 792 TPTLASPVPTTPFLRPVHQVPLVPHVP-----------MVRPAHQLH--PGLVQRMLAQG 838
           +P    P P +    P   VPL+  VP           +  P   +   P  V  +    
Sbjct: 186 SPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVP 245

Query: 839 VHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMV 898
             P  +PSLL +GV  P  D+S    +  P L      LP+    LL+  P  P  +   
Sbjct: 246 SPPSDVPSLL-SGVPSPPSDISPPSDV--PSLLSDVPSLPSDVPSLLSGVPSPPSDV--- 299

Query: 899 QQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLAKW 958
              L   V  PP          V + P ++P  SG+P   S +   PS   S P  +   
Sbjct: 300 -PSLLSDVPSPPS--------DVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLL 350

Query: 959 FG-----SDV-LQQPLPSMPAKVISV 978
            G     SDV L   +PS P+ V S+
Sbjct: 351 SGVPSPLSDVPLLSGVPSPPSDVPSL 376



 Score = 37.4 bits (85), Expect = 0.070
 Identities = 59/223 (26%), Positives = 84/223 (37%), Gaps = 45/223 (20%)

Query: 800 PTTPFLRPVHQV------PLVPHVPMVRPAHQL---HPGLVQRMLAQGVH--PQHLPSLL 848
           P  P + P + +      P+ PH P+V P + L   H  LV  +L+ GV   P  +PSLL
Sbjct: 67  PHHPLMSPHYSLVSPQYSPVSPHCPLVSPHYSLVSPHRPLVSPLLS-GVPSPPSDVPSLL 125

Query: 849 Q------TGVLPPGMDL--------SHLQGISGPILGQPFYPLPAASHP-----LLNPRP 889
                  + V  P  D+        S L G+  P    P  P    S P     LL+  P
Sbjct: 126 SGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVP 185

Query: 890 GTPLHLAMVQQQ---------LQRSVLHPPG-----SGSHAAAVSVQTTPQNVPSRSGLP 935
             P  +               L   V  PP      S   +    V + P +VPS SG+P
Sbjct: 186 SPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVP 245

Query: 936 HMHSQLEHRPSQRSSSPVGLAKWFGSDVLQQPLPSMPAKVISV 978
              S +    S   S P  ++       L   +PS+P+ V S+
Sbjct: 246 SPPSDVPSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSL 288


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 63/279 (22%), Positives = 95/279 (34%), Gaps = 33/279 (11%)

Query: 723 LGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQD 782
           L D K+   ++  E L+  S   S  +   P T++ LS  Q +      + ++ + K Q 
Sbjct: 163 LRDLKQGHVRSLSERLMQMSLATSGVKAHPPVTSAPLSPPQPNDLYKNPTSSSEFYKAQG 222

Query: 783 YRPKATGRKTPTLASPVPTTPFL-RPVHQVPLVPHVP-MVRPAHQLH-PGLVQRMLAQGV 839
             P     K      P P  PF   P   V   P  P      H+L+ PG  +  L +  
Sbjct: 223 PLPNQHSLKGMEHRGPPPEYPFKGMPPQSVVCKPQEPGHFYSEHRLNQPGRTEGQLMRYQ 282

Query: 840 HPQHLPSLLQTGVLPPGMDL----------------SHLQGISGPIL-GQPFYPLPAASH 882
           HP       + G   P  D+                S   G S P+L   P   L  A H
Sbjct: 283 HPP------EYGAARPAQDISLPLSARNSQPHSPTSSLTSGGSLPLLQSPPSTRLSPARH 336

Query: 883 PLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLE 942
           PL+  +     HL   QQ    +  H    G H        + Q    +    H H   +
Sbjct: 337 PLVPNQGDHSAHLPRPQQHFLPNQAH---QGDHYRLSQPGLSQQQQQQQQQHHHHHHHQQ 393

Query: 943 HRPSQRSSSP----VGLAKWFGSDVLQQPLPSMPAKVIS 977
            +  Q    P      + +   S    QP+P+ P  ++S
Sbjct: 394 QQQQQPQQQPGEAYSAMPRAQPSSASYQPVPADPFAIVS 432


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 42/166 (25%), Positives = 62/166 (37%), Gaps = 17/166 (10%)

Query: 651 PQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSP--SFTPTSVIRKMY-- 706
           P VD    G  N   +VT       + N  S +P  +    ++P  S  P S   K    
Sbjct: 83  PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 142

Query: 707 ----ESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSAL 762
               E+  ++KE   + K    D KE T  A E   +  +S     +D +PT+       
Sbjct: 143 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA----KDLAPTSKVLAKPT 198

Query: 763 QRSSCST---PLSQANRYTKEQDYRPKATGRK--TPTLASPVPTTP 803
            ++  +T    L+     T      P +T  K  TPT     PTTP
Sbjct: 199 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 244



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 36/140 (25%), Positives = 54/140 (38%), Gaps = 13/140 (9%)

Query: 669 KSPAPVHRGNSSSPAPAASI-TSMLSPSFTPTSVIRKMYESKEKSKEEPA---SGKAALG 724
           K P P      +S  P     T++ S   TP        +S   + +EPA   + + A  
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273

Query: 725 DSKEDTQKASEENL-LSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDY 783
             KE     ++E    ++ S P+  ++ +PTT  K +       +TP   A    KE   
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP------TTPKEPAPTTPKEPT- 326

Query: 784 RPKATGRKTPTLASPVPTTP 803
            P       PT   P PTTP
Sbjct: 327 -PTTPKEPAPTTKEPAPTTP 345



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 92/481 (19%), Positives = 164/481 (34%), Gaps = 55/481 (11%)

Query: 376 GQNSGNYFAPIPLEDHAE-NKVDILEMLQKAK-VDLKPLLSSLSANKEKLKESS---HSG 430
           G ++G++    P     + NKV     +  AK ++ +P   SL  N +  KE+S   +  
Sbjct: 91  GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP---SLPPNSDTSKETSLTVNKE 147

Query: 431 VVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGDMTAFNKLVS- 489
             +  +E     K    D + K ++    + +E+T +            D+   +K+++ 
Sbjct: 148 TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-----------DLAPTSKVLAK 196

Query: 490 -TMKASGTLPSQPKVSRNLESHLMSPAE----IPGQPVPKNILQELLGQPVQRPASSNLL 544
            T KA  T    P ++   E    +P E     P +P P  I  +      + PA +   
Sbjct: 197 PTPKAETTTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTTPKEPAPTTTK 253

Query: 545 SGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLR------PRIPSPIGFTPGPQQL 598
           S      EP  +   + AP+ P      T    A          P+ P+P          
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313

Query: 599 LGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRD 658
             +P     K  +P T +      ++ A      P   A +      P    P   +   
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373

Query: 659 GFRNRQQRVT--KSPAPVHRGNSSS----PAPAASITSMLSPSFTPTSVIRKMYESKEKS 712
               ++   T  K PAP    ++ +    PAP  + ++  +P     +  ++   +  K 
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 433

Query: 713 KEEPASGKAALGDSKEDTQKASEENLLSSSS----------VPSADRDSSPTTNSKLSAL 762
                  K A    KE      +E   +++            P+  ++++PTT  KL+  
Sbjct: 434 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 493

Query: 763 QRSSCSTPLSQANRYTKEQDYRPKATGRKTPTL-ASPVPTTPFL----RPVHQVPLVPHV 817
                +    +    T  ++  P      TPT    P PTTP       P    P  P  
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553

Query: 818 P 818
           P
Sbjct: 554 P 554



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 56/268 (20%), Positives = 99/268 (36%), Gaps = 44/268 (16%)

Query: 668 TKSPAPVHRGN-------SSSPAPAASITSMLSPSF----TPTSVIRKMYES-KEKSKEE 715
           TK P  +H+         S+ P P A   S   P      TP +   +M  + K+K+ E 
Sbjct: 729 TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788

Query: 716 -----PASGKAALGDSKED---TQKASEENLLSSSS--VPSADRDSSP---------TTN 756
                P +  AA   +KE    T+K +E  + ++++    +  +D++P         T  
Sbjct: 789 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 848

Query: 757 SKLSALQRSSCSTPLSQANRYT---KEQDYRPKAT---------GRKTPTLASPVPTTPF 804
            K++  +++  +T +      T   K++    KAT           K PT      T P 
Sbjct: 849 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 908

Query: 805 LRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQG 864
           +R     P    +    P       + + ML     P   P+     V P   D    +G
Sbjct: 909 VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 968

Query: 865 ISGPILGQPFYPLPAASHPLLNPRPGTP 892
            +  +L +P   +P  + P ++  P  P
Sbjct: 969 ETPHMLLRPHVFMPEVT-PDMDYLPRVP 995


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 42/166 (25%), Positives = 62/166 (37%), Gaps = 17/166 (10%)

Query: 651 PQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSP--SFTPTSVIRKMY-- 706
           P VD    G  N   +VT       + N  S +P  +    ++P  S  P S   K    
Sbjct: 124 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 183

Query: 707 ----ESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSAL 762
               E+  ++KE   + K    D KE T  A E   +  +S     +D +PT+       
Sbjct: 184 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA----KDLAPTSKVLAKPT 239

Query: 763 QRSSCST---PLSQANRYTKEQDYRPKATGRK--TPTLASPVPTTP 803
            ++  +T    L+     T      P +T  K  TPT     PTTP
Sbjct: 240 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 285



 Score = 33.9 bits (76), Expect = 0.77
 Identities = 36/140 (25%), Positives = 54/140 (38%), Gaps = 13/140 (9%)

Query: 669 KSPAPVHRGNSSSPAPAASI-TSMLSPSFTPTSVIRKMYESKEKSKEEPA---SGKAALG 724
           K P P      +S  P     T++ S   TP        +S   + +EPA   + + A  
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314

Query: 725 DSKEDTQKASEENL-LSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDY 783
             KE     ++E    ++ S P+  ++ +PTT  K +       +TP   A    KE   
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP------TTPKEPAPTTPKEPT- 367

Query: 784 RPKATGRKTPTLASPVPTTP 803
            P       PT   P PTTP
Sbjct: 368 -PTTPKEPAPTTKEPAPTTP 386



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 92/481 (19%), Positives = 164/481 (34%), Gaps = 55/481 (11%)

Query: 376 GQNSGNYFAPIPLEDHAE-NKVDILEMLQKAK-VDLKPLLSSLSANKEKLKESS---HSG 430
           G ++G++    P     + NKV     +  AK ++ +P   SL  N +  KE+S   +  
Sbjct: 132 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP---SLPPNSDTSKETSLTVNKE 188

Query: 431 VVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGDMTAFNKLVS- 489
             +  +E     K    D + K ++    + +E+T +            D+   +K+++ 
Sbjct: 189 TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-----------DLAPTSKVLAK 237

Query: 490 -TMKASGTLPSQPKVSRNLESHLMSPAE----IPGQPVPKNILQELLGQPVQRPASSNLL 544
            T KA  T    P ++   E    +P E     P +P P  I  +      + PA +   
Sbjct: 238 PTPKAETTTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTTPKEPAPTTTK 294

Query: 545 SGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLR------PRIPSPIGFTPGPQQL 598
           S      EP  +   + AP+ P      T    A          P+ P+P          
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354

Query: 599 LGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRD 658
             +P     K  +P T +      ++ A      P   A +      P    P   +   
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414

Query: 659 GFRNRQQRVT--KSPAPVHRGNSSS----PAPAASITSMLSPSFTPTSVIRKMYESKEKS 712
               ++   T  K PAP    ++ +    PAP  + ++  +P     +  ++   +  K 
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 474

Query: 713 KEEPASGKAALGDSKEDTQKASEENLLSSSS----------VPSADRDSSPTTNSKLSAL 762
                  K A    KE      +E   +++            P+  ++++PTT  KL+  
Sbjct: 475 PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 534

Query: 763 QRSSCSTPLSQANRYTKEQDYRPKATGRKTPTL-ASPVPTTPFL----RPVHQVPLVPHV 817
                +    +    T  ++  P      TPT    P PTTP       P    P  P  
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594

Query: 818 P 818
           P
Sbjct: 595 P 595



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 56/268 (20%), Positives = 99/268 (36%), Gaps = 44/268 (16%)

Query: 668  TKSPAPVHRGN-------SSSPAPAASITSMLSPSF----TPTSVIRKMYES-KEKSKEE 715
            TK P  +H+         S+ P P A   S   P      TP +   +M  + K+K+ E 
Sbjct: 770  TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829

Query: 716  -----PASGKAALGDSKED---TQKASEENLLSSSS--VPSADRDSSP---------TTN 756
                 P +  AA   +KE    T+K +E  + ++++    +  +D++P         T  
Sbjct: 830  DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 889

Query: 757  SKLSALQRSSCSTPLSQANRYT---KEQDYRPKAT---------GRKTPTLASPVPTTPF 804
             K++  +++  +T +      T   K++    KAT           K PT      T P 
Sbjct: 890  PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 949

Query: 805  LRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQG 864
            +R     P    +    P       + + ML     P   P+     V P   D    +G
Sbjct: 950  VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 1009

Query: 865  ISGPILGQPFYPLPAASHPLLNPRPGTP 892
             +  +L +P   +P  + P ++  P  P
Sbjct: 1010 ETPHMLLRPHVFMPEVT-PDMDYLPRVP 1036


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 42/166 (25%), Positives = 62/166 (37%), Gaps = 17/166 (10%)

Query: 651 PQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSP--SFTPTSVIRKMY-- 706
           P VD    G  N   +VT       + N  S +P  +    ++P  S  P S   K    
Sbjct: 176 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 235

Query: 707 ----ESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSAL 762
               E+  ++KE   + K    D KE T  A E   +  +S     +D +PT+       
Sbjct: 236 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA----KDLAPTSKVLAKPT 291

Query: 763 QRSSCST---PLSQANRYTKEQDYRPKATGRK--TPTLASPVPTTP 803
            ++  +T    L+     T      P +T  K  TPT     PTTP
Sbjct: 292 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 337



 Score = 34.3 bits (77), Expect = 0.59
 Identities = 107/551 (19%), Positives = 188/551 (34%), Gaps = 70/551 (12%)

Query: 324 EDVLGEGSVSASRFSRWFSNPSRSGSR----SSSLGSTPHEELERLAGLEQAILSPGQNS 379
           E++  E SVS ++ S   S+ S S S      SS  S  + EL++   ++    +  +  
Sbjct: 111 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 170

Query: 380 GNYFAPIPLE-----DHAENKVDILEM--LQKAKVDLKPLLS---------SLSANKEKL 423
                P+  E     D+ + KV   +    Q  KV   P ++         SL  N +  
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230

Query: 424 KESS---HSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGD 480
           KE+S   +    +  +E     K    D + K ++    + +E+T +            D
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-----------D 279

Query: 481 MTAFNKLVS--TMKASGTLPSQPKVSRNLESHLMSPAE----IPGQPVPKNILQELLGQP 534
           +   +K+++  T KA  T    P ++   E    +P E     P +P P  I  +     
Sbjct: 280 LAPTSKVLAKPTPKAETTTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTT 336

Query: 535 VQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLR------PRIPSP 588
            + PA +   S      EP  +   + AP+ P      T    A          P+ P+P
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396

Query: 589 IGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGF 648
                       +P     K  +P T +      ++ A      P   A +      P  
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 456

Query: 649 GKPQVDRTRDGFRNRQQRVT--KSPAPVHRGNSSS----PAPAASITSMLSPSFTPTSVI 702
             P   +       ++   T  K PAP    ++ +    PAP  + ++  +P     +  
Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516

Query: 703 RKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSS----------VPSADRDSS 752
           ++   +  K        K A    KE      +E   +++            P+  ++++
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576

Query: 753 PTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTL-ASPVPTTPFL----RP 807
           PTT  KL+       +    +    T  ++  P      TPT    P PTTP       P
Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 636

Query: 808 VHQVPLVPHVP 818
               P  P  P
Sbjct: 637 KEPAPTTPKEP 647



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 56/268 (20%), Positives = 99/268 (36%), Gaps = 44/268 (16%)

Query: 668  TKSPAPVHRGN-------SSSPAPAASITSMLSPSF----TPTSVIRKMYES-KEKSKEE 715
            TK P  +H+         S+ P P A   S   P      TP +   +M  + K+K+ E 
Sbjct: 822  TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881

Query: 716  -----PASGKAALGDSKED---TQKASEENLLSSSS--VPSADRDSSP---------TTN 756
                 P +  AA   +KE    T+K +E  + ++++    +  +D++P         T  
Sbjct: 882  DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 941

Query: 757  SKLSALQRSSCSTPLSQANRYT---KEQDYRPKAT---------GRKTPTLASPVPTTPF 804
             K++  +++  +T +      T   K++    KAT           K PT      T P 
Sbjct: 942  PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1001

Query: 805  LRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQG 864
            +R     P    +    P       + + ML     P   P+     V P   D    +G
Sbjct: 1002 VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 1061

Query: 865  ISGPILGQPFYPLPAASHPLLNPRPGTP 892
             +  +L +P   +P  + P ++  P  P
Sbjct: 1062 ETPHMLLRPHVFMPEVT-PDMDYLPRVP 1088


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 42/166 (25%), Positives = 62/166 (37%), Gaps = 17/166 (10%)

Query: 651 PQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSP--SFTPTSVIRKMY-- 706
           P VD    G  N   +VT       + N  S +P  +    ++P  S  P S   K    
Sbjct: 217 PVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL 276

Query: 707 ----ESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSAL 762
               E+  ++KE   + K    D KE T  A E   +  +S     +D +PT+       
Sbjct: 277 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSA----KDLAPTSKVLAKPT 332

Query: 763 QRSSCST---PLSQANRYTKEQDYRPKATGRK--TPTLASPVPTTP 803
            ++  +T    L+     T      P +T  K  TPT     PTTP
Sbjct: 333 PKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 378



 Score = 34.3 bits (77), Expect = 0.59
 Identities = 107/551 (19%), Positives = 188/551 (34%), Gaps = 70/551 (12%)

Query: 324 EDVLGEGSVSASRFSRWFSNPSRSGSR----SSSLGSTPHEELERLAGLEQAILSPGQNS 379
           E++  E SVS ++ S   S+ S S S      SS  S  + EL++   ++    +  +  
Sbjct: 152 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 211

Query: 380 GNYFAPIPLE-----DHAENKVDILEM--LQKAKVDLKPLLS---------SLSANKEKL 423
                P+  E     D+ + KV   +    Q  KV   P ++         SL  N +  
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271

Query: 424 KESS---HSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGD 480
           KE+S   +    +  +E     K    D + K ++    + +E+T +            D
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-----------D 320

Query: 481 MTAFNKLVS--TMKASGTLPSQPKVSRNLESHLMSPAE----IPGQPVPKNILQELLGQP 534
           +   +K+++  T KA  T    P ++   E    +P E     P +P P  I  +     
Sbjct: 321 LAPTSKVLAKPTPKAETTTKG-PALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTT 377

Query: 535 VQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLR------PRIPSP 588
            + PA +   S      EP  +   + AP+ P      T    A          P+ P+P
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437

Query: 589 IGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGF 648
                       +P     K  +P T +      ++ A      P   A +      P  
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 497

Query: 649 GKPQVDRTRDGFRNRQQRVT--KSPAPVHRGNSSS----PAPAASITSMLSPSFTPTSVI 702
             P   +       ++   T  K PAP    ++ +    PAP  + ++  +P     +  
Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557

Query: 703 RKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSS----------VPSADRDSS 752
           ++   +  K        K A    KE      +E   +++            P+  ++++
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617

Query: 753 PTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTL-ASPVPTTPFL----RP 807
           PTT  KL+       +    +    T  ++  P      TPT    P PTTP       P
Sbjct: 618 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP 677

Query: 808 VHQVPLVPHVP 818
               P  P  P
Sbjct: 678 KEPAPTTPKEP 688



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 56/268 (20%), Positives = 99/268 (36%), Gaps = 44/268 (16%)

Query: 668  TKSPAPVHRGN-------SSSPAPAASITSMLSPSF----TPTSVIRKMYES-KEKSKEE 715
            TK P  +H+         S+ P P A   S   P      TP +   +M  + K+K+ E 
Sbjct: 863  TKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922

Query: 716  -----PASGKAALGDSKED---TQKASEENLLSSSS--VPSADRDSSP---------TTN 756
                 P +  AA   +KE    T+K +E  + ++++    +  +D++P         T  
Sbjct: 923  DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 982

Query: 757  SKLSALQRSSCSTPLSQANRYT---KEQDYRPKAT---------GRKTPTLASPVPTTPF 804
             K++  +++  +T +      T   K++    KAT           K PT      T P 
Sbjct: 983  PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPR 1042

Query: 805  LRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQG 864
            +R     P    +    P       + + ML     P   P+     V P   D    +G
Sbjct: 1043 VRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEG 1102

Query: 865  ISGPILGQPFYPLPAASHPLLNPRPGTP 892
             +  +L +P   +P  + P ++  P  P
Sbjct: 1103 ETPHMLLRPHVFMPEVT-PDMDYLPRVP 1129


>gi|117938768 GNAS complex locus alex [Homo sapiens]
          Length = 626

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 105/457 (22%), Positives = 158/457 (34%), Gaps = 70/457 (15%)

Query: 513 SPAEIPGQPVPKNIL----QELLGQPVQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLS 568
           SP  +P  P P  +     +E    P++R    +L+   +G+              P LS
Sbjct: 132 SPELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGF-------PELS 184

Query: 569 QVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLEL-QQAAL 627
               T AAS+   RPR+ S    +  P+  L     G + P +    ++S L L  +AA 
Sbjct: 185 HK-STAAASSRQSRPRVRSA---SLPPRTRLPS---GSQAPSAAHPKRLSDLLLTSRAAA 237

Query: 628 EGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAAS 687
            G   P   +  AA    P  G   +  T   +   Q R+T  P       S SP P   
Sbjct: 238 PGWRSPDPRSRLAA----PPLGSTTLPST---WTAPQSRLTARP-------SRSPEPQIR 283

Query: 688 ITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSA 747
            +    P         K      + ++ P  G   L   +        + L     +   
Sbjct: 284 ESEQRDPQLRRKQQRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPG 343

Query: 748 DRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDY----RPKATGRKTPTLASPVPTTP 803
                PT       L     S P+    +    Q      RP  T +  PT   P+   P
Sbjct: 344 QPQKIPTPGQHQPILTPGH-SQPIPTPGQPLPPQPIPTPGRP-LTPQPIPTPGRPLTPQP 401

Query: 804 FLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQ 863
              P   + L P + ++RP   + P L Q         Q LP  L   +LPPG   S   
Sbjct: 402 IQMPGRPLRLPPPLRLLRPGQPMSPQLRQ--------TQGLP--LPQPLLPPGQPKS--- 448

Query: 864 GISGPILGQPFYPLP------AASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAA 917
                  G+P  PLP      + S P   P P + L + +++  L R    P G+   AA
Sbjct: 449 ------AGRPLQPLPPGPDARSISDP---PAPRSRLPIRLLRGLLARL---PGGASPRAA 496

Query: 918 AVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVG 954
           A +  TT +  P+ +  P   S     P   +   +G
Sbjct: 497 AAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIG 533


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 76/346 (21%), Positives = 113/346 (32%), Gaps = 69/346 (19%)

Query: 663 RQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAA 722
           R+ R  K PAP        P    S+    S S +PT   +K  + K++ +   +S    
Sbjct: 155 RRAREAKQPAP-------EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSP-- 205

Query: 723 LGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSAL----QRSSCSTPLSQANRYT 778
               + + +K+S++    S S     +  SPT  SK  +     +RS  +TP  ++ R  
Sbjct: 206 ----RRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH 261

Query: 779 KEQDY-----------RPKATGRKTPTLA----SPVPTT--------PFLRP---VHQVP 812
           +               R ++   KT T A    SP P +        PF  P     Q P
Sbjct: 262 RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321

Query: 813 LVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMD--LSHLQGISG--- 867
             P     +P+         +       P   P    TG  PP     L+   G S    
Sbjct: 322 SSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPL 381

Query: 868 ---PILGQPFYP------------------LPAASHPLLNPRPGTPLHLAMVQQQLQRSV 906
              P+  +P  P                  LP +S    +P    P  ++        S 
Sbjct: 382 ATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441

Query: 907 LHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSP 952
              P  GSH    S  T+      R+     HS    R   RS SP
Sbjct: 442 KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSP 487



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 126/574 (21%), Positives = 202/574 (35%), Gaps = 119/574 (20%)

Query: 273  EEDEVEVI-LAQEPAADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGS 331
            +E+ +EV+  ++EPA        + L E S  +F+ +    +++ P ++  ++    + S
Sbjct: 1235 DEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP--EVEERPAVSLTLDQSQSQAS 1292

Query: 332  VSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSPGQ--NSGNYFAPIPLE 389
            + A         PS + S      S  H+EL      E +  SP +  NSG    P+  E
Sbjct: 1293 LEAVEV------PSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSG----PLGTE 1342

Query: 390  DHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQ 449
             +     ++ E L    ++      SL   ++  + S HS   LS + VE    G+  +Q
Sbjct: 1343 MNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA--GMSSNQ 1400

Query: 450  QVKN------------------STPFMAEHLEETLSAVTNNRQLK--KDGDMTAFNKLVS 489
             + +                  S+P M + L  T S  + +      +DG  T      S
Sbjct: 1401 SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP-----S 1455

Query: 490  TMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMG 549
                SG+ P    + R         +E    P PK + Q    +P  R  SS  L+    
Sbjct: 1456 RHSLSGSSPGMKDIPRTPSR---GRSECDSSPEPKALPQT--PRPRSRSPSSPELNN--- 1507

Query: 550  SLEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLL-----GDPFQ 604
                   L  QR  S   S V Q   A       R P       G  Q L       P +
Sbjct: 1508 -----KCLTPQRERSGSESSVDQKTVA-------RTPLGQRSRSGSSQELDVKPSASPQE 1555

Query: 605  GMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVD--------RT 656
                  SP +   ++  L+Q +  G                     P+VD        R+
Sbjct: 1556 RSESDSSPDSKAKTRTPLRQRSRSG-------------------SSPEVDSKSRLSPRRS 1596

Query: 657  RDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEP 716
            R G     +   ++      G+ SSP P A      +P   P    R    S  K +   
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAP-----APRALPR---RSRSGSSSKGRGPS 1648

Query: 717  ASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTP------ 770
              G ++   S E   K+      S SS         P T S+    +RSS S+P      
Sbjct: 1649 PEGSSSTESSPEHPPKSRTARRGSRSS-------PEPKTKSRTPPRRRSSRSSPELTRKA 1701

Query: 771  -LSQANR---YTKEQDYRPKATGRKTPTLASPVP 800
             LS+ +R    + E   R     R++P+++SP P
Sbjct: 1702 RLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735



 Score = 38.5 bits (88), Expect = 0.031
 Identities = 58/255 (22%), Positives = 89/255 (34%), Gaps = 15/255 (5%)

Query: 494  SGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEP 553
            S T PS P  SR       SP+   GQ   +++L     QP + P  S         +  
Sbjct: 2407 SRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQP-RSPVPSAFSDQSRCLIAQ 2465

Query: 554  TTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPG-PQQLLGDPFQGMRKPMSP 612
            TT + G ++ S   S    T  +SA      +  P    PG P   +G+P      P S 
Sbjct: 2466 TTPVAGSQSLS---SGAVATTTSSAGDHNGMLSVP---APGVPHSDVGEP------PAST 2513

Query: 613  ITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTKSP- 671
               Q S L   Q A E  +     +  +++                   +    +   P 
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573

Query: 672  APVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQ 731
              + R  S +PAP  ++     P  TP    R+   S   S    +S  ++   S   + 
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633

Query: 732  KASEENLLSSSSVPS 746
             +S  +  SSSS  S
Sbjct: 2634 SSSSSSSSSSSSSSS 2648



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 68/304 (22%), Positives = 101/304 (33%), Gaps = 43/304 (14%)

Query: 669  KSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKE 728
            KS  P  R  S S  P A        S TP          + +S   P   + +   S++
Sbjct: 789  KSQTPPRRSRSGSSQPKAK-------SRTPPR--------RSRSSSSPPPKQKSKTPSRQ 833

Query: 729  DTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSC--STPLSQANRYTKEQDYRPK 786
                +S    + S + P     +SP  N +    QR SC  S+P  +    T     R  
Sbjct: 834  SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS---RHS 890

Query: 787  ATGRKTPTLASPVPTTPFLRPVHQVPLVPHV-PMVRPAHQLHPGLVQRMLAQGVHPQHLP 845
             +G   P + S  P  P   P       P V  ++ P  + H G               P
Sbjct: 891  CSGSSPPRVKSSTP--PRQSPSRSSSPQPKVKAIISPRQRSHSG----------SSSPSP 938

Query: 846  SLLQTGVLP-PGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTP---LHLAMVQQQ 901
            S + +   P     +S    +   +L  P Y    +S P    +P TP    H   +   
Sbjct: 939  SRVTSRTTPRRSRSVSPCSNVESRLL--PRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996

Query: 902  LQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLAKWFGS 961
             +     PPG    + + S    PQ     S +      L      +SS+P G   +FG 
Sbjct: 997  PKVKAQTPPGP---SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPG-ESYFGV 1052

Query: 962  DVLQ 965
              LQ
Sbjct: 1053 SSLQ 1056



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 64/288 (22%), Positives = 106/288 (36%), Gaps = 32/288 (11%)

Query: 536  QRPASSNLLSGLMGSLEPTTSLLGQR-----APSPPLSQVFQTRAASADYLRPRIPSPI- 589
            Q PAS+NL+           ++ G R     AP+   S       + A+   PR+P    
Sbjct: 2331 QAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAY 2390

Query: 590  ----GFTPGPQQLLGDPFQGMRKPMSPITAQM-SQLELQQAALEGLALPHDLAVQAANFY 644
                G T  P   L D  +    P +P  ++M S+     ++  G A    L   A +  
Sbjct: 2391 ERVSGRTSPP---LLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD-- 2445

Query: 645  QPGFGKPQV--DRTR------------DGFRNRQQRVTKSPAPVHRGNSSSPAPAASITS 690
            QP    P    D++R                +     T S A  H G  S PAP    + 
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505

Query: 691  MLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRD 750
            +  P  +  +       + + +KE  +S  ++   S   +  +S  +  SSS   S+D +
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSS-SSSSSSSSSSSSSSSSSSSGSSSSDSE 2564

Query: 751  SSPTTNSKLSALQRSSCSTPL-SQANRYTKEQDYRPKATGRKTPTLAS 797
             S        AL+R    TP   +A R  +  +  P    R++ + +S
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612



 Score = 30.4 bits (67), Expect = 8.5
 Identities = 69/350 (19%), Positives = 120/350 (34%), Gaps = 40/350 (11%)

Query: 346  RSGSRSSSLGSTPHEELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKA 405
            R+ S SS +G  P           Q++L P Q+      P    D +   +      Q  
Sbjct: 2423 RAPSPSSRMGQAP----------SQSLLPPAQDQPRSPVPSAFSDQSRCLI-----AQTT 2467

Query: 406  KVDLKPLLSSLSANKEKLKESSHSGVVL----SVEEVEAGLKGLKVDQQVKNSTPFMAEH 461
             V     LSS +          H+G++      V   + G        Q  ++   +   
Sbjct: 2468 PVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPA 2527

Query: 462  LEETLSAVTNNRQLKKDGDMTAFNKLVSTMKASG-----TLPSQPKVSRNLESHLMSPAE 516
             E   S+ +++         ++ +   S+  +S      +LP QP+V+      + SP  
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK---RVPSPTP 2584

Query: 517  IPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAA 576
             P + V +    E      +R +SS+  S    S   ++S     + S   S    + ++
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 577  SADYLRPRIPSPIGFTPGPQQLLGDP--FQGMRKPMSPITAQMSQLELQQAALEGLALPH 634
            S+    P  P P    P P      P   +  R P  PI +      L  + +E      
Sbjct: 2645 SSSSPSPAKPGPQAL-PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE------ 2697

Query: 635  DLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAP 684
                +     QP     Q   +  G R  Q+  ++SP+   R  + SP P
Sbjct: 2698 ----RRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRP 2743


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 49/187 (26%), Positives = 71/187 (37%), Gaps = 23/187 (12%)

Query: 784 RPKATGRKTPTLASPVPTTPFLRPVHQVPL---VPHV-PMVRPAHQLHPGLVQRMLAQGV 839
           +P   G++ P LA P P    L P   VPL    PH+ P + PA Q+      + L    
Sbjct: 723 QPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQ 782

Query: 840 HP-----QHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHP------LLNPR 888
            P     Q  P +    V+PP   L+ + G+   +   P   +P    P      ++ P 
Sbjct: 783 APLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPS 842

Query: 889 PGTPLHLAMVQQQLQRSVL-HPPGSG-SHAAAVSVQTTPQNVPSRSGLP------HMHSQ 940
              PL  A     LQ   L HPPG+  +      V   P  +P  +  P       +HS 
Sbjct: 843 LAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSA 902

Query: 941 LEHRPSQ 947
           +   P Q
Sbjct: 903 VAQLPGQ 909



 Score = 35.0 bits (79), Expect = 0.35
 Identities = 30/106 (28%), Positives = 43/106 (40%), Gaps = 20/106 (18%)

Query: 793 PTLASPVPTTPFLRPVHQV--PLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQT 850
           P+LA+P+P      P+  V  P  P  P+  P   + P            P  +P L   
Sbjct: 841 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNA----------PATIPLL--- 887

Query: 851 GVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPR--PGTPLH 894
            V PPG+    +      + GQP YP   A+ P + P   P +P H
Sbjct: 888 AVAPPGVAALSIHSAVAQLPGQPVYP---AAFPQMAPTDVPPSPHH 930



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 36/139 (25%), Positives = 51/139 (36%), Gaps = 6/139 (4%)

Query: 839 VHPQHLPSL--LQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLA 896
           V PQ LPSL   Q     PG+ +  +   + P   Q  +P PA S   + P P TP+   
Sbjct: 661 VLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTG 720

Query: 897 MVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSSPVGLA 956
             Q         PP          V      VP +   PH+   L   P+ +  +P  L 
Sbjct: 721 PGQPAPPGQ--QPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYL--APASQVGAPAQLK 776

Query: 957 KWFGSDVLQQPLPSMPAKV 975
                    QPL  +P ++
Sbjct: 777 PLQMPQAPLQPLAQVPPQM 795



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 58/215 (26%), Positives = 80/215 (37%), Gaps = 30/215 (13%)

Query: 667  VTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDS 726
            V + PAP     SS P P +S+    S    P       Y+ +  SKE+P+        S
Sbjct: 1318 VAEHPAP-EAPESSPPLPLSSLPPEASQDSAP-------YKDQLSSKEQPS-----FLAS 1364

Query: 727  KEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPK 786
            ++   +A   N   +   P A   SSP   +        + ST    A+    +      
Sbjct: 1365 QQLLSQAGPSNPPGAPPAPLAP--SSPPVTALPQDGAAPATSTMPEPASGTASQ------ 1416

Query: 787  ATGRKTPT-LASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLP 845
            A G  TP  L S + T+  L   H+ PL      V+P   L  GL     A         
Sbjct: 1417 AGGPGTPQGLTSELETSQPLAETHEAPLA-----VQP---LVVGLAPCTPAPEAASTRDA 1468

Query: 846  SLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAA 880
            S  +  + PP  + S   G   P LGQP   LPAA
Sbjct: 1469 SAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAA 1503


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 76/310 (24%), Positives = 96/310 (30%), Gaps = 52/310 (16%)

Query: 668  TKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSK 727
            T  P P    ++S   P  ++TS  S   TP S +     S       P    A+   + 
Sbjct: 1002 TAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPAS--RTN 1059

Query: 728  EDTQKASEENLLS---SSSVPSADRDSSPTTNSKLSALQRSSCSTP-----LSQANRYTK 779
             D    S +  LS   SS VP+   + SPT    L     S  STP     LS  +    
Sbjct: 1060 PDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVP 1119

Query: 780  EQDYRP-----------KATGRKTPTLASPVPTT---PFLRP----VHQVPLVPHVPMV- 820
            E D  P               R      SP PTT   P + P         + PH P   
Sbjct: 1120 ESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTP 1179

Query: 821  RPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGP-ILGQPF----- 874
             P    HP  +        H   +P    T    P   ++H   I  P    QPF     
Sbjct: 1180 HPTTTPHPTTI-------THSTMIPD--PTTTPQPFTTITHSTMIPDPTTTPQPFTTMQP 1230

Query: 875  --YPLPAASHPLLNPRPGTPLHLAMVQQQL---QRSVLHPPGSGSHAAAVSVQTT---PQ 926
               P     HP   P P T  H  M+       Q      P +  H       TT   P 
Sbjct: 1231 TTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPT 1290

Query: 927  NVPSRSGLPH 936
              P  +  PH
Sbjct: 1291 TTPHPTTTPH 1300


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 49/156 (31%), Positives = 59/156 (37%), Gaps = 48/156 (30%)

Query: 787 ATGRKTPT-LASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLP 845
           ATG+  P   A P P  P   P       P  P++RP +             G +PQ L 
Sbjct: 601 ATGQPQPQGTAQPPPGAPQGPPGAASGPPPPGPILRPQNP------------GANPQ-LR 647

Query: 846 SLL------QTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQ 899
           SLL      QTGV PP   L HLQ    P L      LP             P H  + Q
Sbjct: 648 SLLLNPPPPQTGVPPPQASLHHLQPPGAPAL------LP-------------PPHQGLGQ 688

Query: 900 QQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLP 935
            QL   +LHPP           Q+ P  +P R+ LP
Sbjct: 689 PQLGPPLLHPP---------PAQSWPAQLPPRAPLP 715


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 89/409 (21%), Positives = 148/409 (36%), Gaps = 70/409 (17%)

Query: 465  TLSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPK 524
            T S  T +      G MTA     ++ + + T P+       L +H+   +     P   
Sbjct: 1968 THSPPTGSSPFSSTGPMTA-----TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTH 2022

Query: 525  NILQELLGQPVQRPASSNLLSGLMGSLEPTTSL--LGQRAPSPPLSQV----------FQ 572
             ++   +    Q   S+++ S   G++ P T+L   G    +PP++            F 
Sbjct: 2023 TVI---ITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFS 2079

Query: 573  TRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLAL 632
            T  AS+ ++      P   +  P             P SPIT Q+  L            
Sbjct: 2080 TATASSSFISSSSWLPQNSSSRP-------------PSSPITTQLPHLS-------SATT 2119

Query: 633  PHDLAVQAANFYQPGFGKPQVDRTRDGF--RNRQQRVTKSPAPVHRGNSSSPAPAASITS 690
            P     Q ++ + P    P    T   +   +     T SP+    G SSS   A   ++
Sbjct: 2120 PVSTTNQLSSSFSPS---PSAPSTVSSYVPSSHSSPQTSSPSV---GTSSSFVSAPVHST 2173

Query: 691  MLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSS-----SSVP 745
             LS     +        S   S   P+S  A+       T +A+  + +SS     + +P
Sbjct: 2174 TLSSGSHSSLSTHPTTASVSASPLFPSSPAAST------TIRATLPHTISSPFTLSALLP 2227

Query: 746  SADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFL 805
             +    SPT +S L++   +  STP + A+ +T         T R T +L + VPT+ F+
Sbjct: 2228 ISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRST-SLTTRVPTSGFV 2286

Query: 806  RPVHQVPLVPHVPMVRPAHQLHPG---------LVQRMLAQGVHPQHLP 845
                 V  +P  P+     + HPG         L   + A G  P   P
Sbjct: 2287 SLTSGVTGIPTSPVTNLTTR-HPGPTLSPTTRFLTSSLTAHGSTPASAP 2334



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 37/156 (23%), Positives = 55/156 (35%), Gaps = 9/156 (5%)

Query: 739  LSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASP 798
            L SS+ PS   + +P + ++   L  +  S+      + T      P+ T   TP   S 
Sbjct: 1232 LLSSTGPSPSSNHTPASPTQTPLLPATLTSS------KPTASSGEPPRPTTAVTPQATSG 1285

Query: 799  VPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLP--PG 856
            +P T  LR     P V        A    P       +       LP+   +G  P  P 
Sbjct: 1286 LPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPK 1345

Query: 857  MDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTP 892
                 L G +      P  P PA++     P+PG P
Sbjct: 1346 STNQELPGTTATQTTGP-RPTPASTTGPTTPQPGQP 1380



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 67/318 (21%), Positives = 106/318 (33%), Gaps = 74/318 (23%)

Query: 682  PAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSS 741
            P P  ++T   +    PT+ +R    +  K     A+ +A    +   T   ++    ++
Sbjct: 1272 PRPTTAVTPQATSGLPPTATLRS---TATKPTVTQATTRATASTASPATTSTAQSTTRTT 1328

Query: 742  SSVPS-ADRDSSPT----TNSKLSALQRSSCS----TPLSQANRYTKE--QDYRPKATG- 789
             ++P+ A   +SPT    TN +L     +  +    TP S     T +  Q  RP AT  
Sbjct: 1329 MTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATET 1388

Query: 790  ------------------RKTPTLASPVP------------TTPFLRPVHQVPLVP-HVP 818
                                 PT  SPVP            TT +  P H    +P HVP
Sbjct: 1389 TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVP 1448

Query: 819  -----MVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQP 873
                 +V P+           +A        P    TG +PP   L      +G     P
Sbjct: 1449 PFSTSLVTPSTHTVITPTHAQMATSASNHSAP----TGTIPPPTTLK----ATGSTHTAP 1500

Query: 874  FYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTT------PQN 927
                     P+     GT    +        + LH   S +H   V+  +T      P +
Sbjct: 1501 ---------PITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551

Query: 928  VPSRSGLPHMHSQLEHRP 945
              +R+ + H +S    RP
Sbjct: 1552 TRTRTPVAHTNSATSSRP 1569



 Score = 31.2 bits (69), Expect = 5.0
 Identities = 58/278 (20%), Positives = 98/278 (35%), Gaps = 31/278 (11%)

Query: 667  VTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDS 726
            VT S   V     +  A +ASI S  + +  P + ++    +         +   +   S
Sbjct: 2017 VTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHS 2076

Query: 727  KEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPK 786
               T  AS   + SSS +P       P++         SS +TP+S  N+ +      P 
Sbjct: 2077 SFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPS 2136

Query: 787  ATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPS 846
            A      T++S VP++      H  P      +   +  +   +    L+ G H     S
Sbjct: 2137 APS----TVSSYVPSS------HSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSH-----S 2181

Query: 847  LLQTGVLPPGMDLSHLQGISGPILGQPFYP-LPAASHPLLNPRPGT---PLHLAMVQQQL 902
             L T               +  +   P +P  PAAS  +    P T   P  L+ +    
Sbjct: 2182 SLST------------HPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPIS 2229

Query: 903  QRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHSQ 940
              +V   P S   ++ ++  +TP+   S    P   SQ
Sbjct: 2230 TVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQ 2267


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score = 39.3 bits (90), Expect = 0.018
 Identities = 97/455 (21%), Positives = 170/455 (37%), Gaps = 74/455 (16%)

Query: 538 PASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQ 597
           P +S++ +    +   T +    R   P +S    +   +   ++  +  P        Q
Sbjct: 19  PGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRP---PSSAAQ 75

Query: 598 LLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRT- 656
            L   +   ++ +   TA + Q  L  + L+ LA     AVQA+       G+P    T 
Sbjct: 76  YLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSLA-----AVQASL----SSGRPSTSPTG 126

Query: 657 ----RDGFRNRQQRVTKSPAP---VHRGNSSSPAPAASIT--SMLSPSFTPTSVIRK--M 705
               +         ++ SP P   + R  +SS + + SIT  +ML  S +PT    +  M
Sbjct: 127 SVTQQSSMSQTSINLSTSPTPAQLISRSQASS-STSGSITQQTMLLGSTSPTLTASQAQM 185

Query: 706 YESKEKSKEEPASGKAAL--------GDSKEDTQKASEE--NLLSSSS---VPSADRDSS 752
           Y   +     PA+  AA+          S    Q A+ +  NL   S    V S+ ++  
Sbjct: 186 YLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGP 245

Query: 753 PTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGR-KTPTLASPVPTTPFLRPVHQV 811
           P + S+  +L  + C    +  +    ++D  P++  + ++P+L S          +HQ+
Sbjct: 246 PKSTSQTQSL--TICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQL 303

Query: 812 -------PLVPH-------VPMVRPAHQL-HPGLVQRMLAQGVHPQHLPSLLQTGVLPPG 856
                  P+ PH       +P+  P  ++ H  L+ +   Q + P  L +  Q    PP 
Sbjct: 304 IAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLILQQQQQQIQPITLQNSTQDP--PPS 361

Query: 857 MDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHA 916
                LQ           + LP A      P      H + +Q       + P  S S  
Sbjct: 362 QHCIPLQN----------HGLPPA------PSNAQSQHCSPIQSHPSPLTVSPNQSQSAQ 405

Query: 917 AAVSVQTTPQNVPSRSGLPHMHSQLEHRPSQRSSS 951
            +V V   P + PS+S    +H Q   +P    SS
Sbjct: 406 QSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSS 440


>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
          Length = 1217

 Score = 39.3 bits (90), Expect = 0.018
 Identities = 67/301 (22%), Positives = 111/301 (36%), Gaps = 39/301 (12%)

Query: 670 SPAPVHRG--NSSSPAPAASITSMLSPSFTPTSVIRKMYESKEK-------SKEEPASGK 720
           +P+P++     S SPA ++++++  +PS +  + +RK+ +  E+       S+  P S  
Sbjct: 30  TPSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSP 89

Query: 721 AALGDSKEDTQKASEENLL----SSSSVPSADR----DSSPTTNSKLSALQRSSCSTPLS 772
           A    S   T K      +       SVPS         + T N    +  R    +  S
Sbjct: 90  ATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSS 149

Query: 773 QANR---YTKEQDYRPKATGRKTPT--LASPVPTTPFLRPVHQVPLVPHVPMVRPAHQ-L 826
              R     +    + KA G   P+  L++P P       V Q    P + + RP H  +
Sbjct: 150 SGGRERLIVEPPLPQEKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVV 209

Query: 827 HPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLN 886
            P  V     +   P H    L+   LPP        G+        ++P   A HP   
Sbjct: 210 PPSTVTEDYLRSFRPYHTTDDLRMSSLPP-------LGLDPATAAAYYHPSYLAPHPF-- 260

Query: 887 PRPGTPLHLAMVQQQLQRSVLHPPGSGS----HAAAVSVQTTPQNVP---SRSGLPHMHS 939
           P P   +  +     L+      P  GS    H +A+ +  +    P   S S L  +HS
Sbjct: 261 PHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHS 320

Query: 940 Q 940
           +
Sbjct: 321 E 321


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 39.3 bits (90), Expect = 0.018
 Identities = 39/125 (31%), Positives = 53/125 (42%), Gaps = 17/125 (13%)

Query: 661 RNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGK 720
           R R  + + SP PV RG SSSP    S     SPS  P   IR++  +      EP   K
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQS----PSPSTRP---IRRVSRT-----PEPKKIK 734

Query: 721 AALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKE 780
            A   S +  ++ S    +S S  P+A +  +P      S +Q  S ST  S A    K 
Sbjct: 735 KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP-----SPVQSQSPSTNWSPAVPVKKA 789

Query: 781 QDYRP 785
           +   P
Sbjct: 790 KSPTP 794



 Score = 37.0 bits (84), Expect = 0.091
 Identities = 82/344 (23%), Positives = 123/344 (35%), Gaps = 72/344 (20%)

Query: 661 RNRQQRVTKSPAPV------HRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKE 714
           R R+ RV+ SP         H+G     +P        SP+  P  V  ++ ES     E
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESP--------SPAPKPRKV--ELSES-----E 466

Query: 715 EPASGKAALGDSKEDTQKASEENLLSS--SSVPSADRDSSP----TTNSKLSALQRSSCS 768
           E   GK A  DS +  ++   +N  SS  S   S+  D  P      N ++   +R S S
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526

Query: 769 TPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHP 828
              S + R  ++++  P+   R++P   SP PT     P          P   P  +  P
Sbjct: 527 RSASPSPR-KRQKETSPRGRRRRSP---SPPPTRRRRSP---------SPAPPPRRRRTP 573

Query: 829 GLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPR 888
               R        +  PS       PP    S       P + + + P P       +P 
Sbjct: 574 TPPPR--------RRTPS-------PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP- 617

Query: 889 PGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQ--------NVPSRSGLPHMHSQ 940
           P  P   A      +R V H P     ++ V+ + +P         + PSRS       Q
Sbjct: 618 PPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677

Query: 941 --LEHRPS------QRSSSPVGLAKWFGSDVLQQPLPSMPAKVI 976
               H PS      Q SSSP  + +   S   ++  PS   + I
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPI 721



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 56/262 (21%), Positives = 89/262 (33%), Gaps = 39/262 (14%)

Query: 661 RNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSP---SFTPTSVIRKMYES--------- 708
           R R++R + SP P  R  S SPAP        +P     TP+   R+   S         
Sbjct: 543 RGRRRR-SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQ 601

Query: 709 ---------KEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKL 759
                    K ++   P   K     S    ++ S        S P   R  SP+ +SK 
Sbjct: 602 RRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKR-RSPSLSSKH 660

Query: 760 SALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPV------------PTTPFLRP 807
                 S ST  +++ +  K     P+    +T +   PV              +P  RP
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720

Query: 808 VHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISG 867
           + +V   P    ++ A    P  V+R+ +     + +    +     P    S +Q  S 
Sbjct: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSS----RSVSGSPEPAAKKPPAPPSPVQSQSP 776

Query: 868 PILGQPFYPLPAASHPLLNPRP 889
                P  P+  A  P  +P P
Sbjct: 777 STNWSPAVPVKKAKSPTPSPSP 798


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,423,778
Number of Sequences: 37866
Number of extensions: 2449286
Number of successful extensions: 9748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 8672
Number of HSP's gapped (non-prelim): 1377
length of query: 985
length of database: 18,247,518
effective HSP length: 112
effective length of query: 873
effective length of database: 14,006,526
effective search space: 12227697198
effective search space used: 12227697198
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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