Guide to the Human Genome
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Name: LEF1 Sequence: fasta or formatted (399aa) NCBI GI: 7705917
Description:

lymphoid enhancer-binding factor 1 isoform 1

Referenced in:

SOX Family
T cells

Other entries for this name:
alt prot [371aa] lymphoid enhancer-binding factor 1 isoform 2
alt prot [386aa] lymphoid enhancer-binding factor 1 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         22           2
 C cysteine            0.5          2           1
 D aspartate           4.5         18           2
 E glutamate           6.8         27           3
 F phenylalanine       1.8          7           1
 G glycine             8.5         34           8
 H histidine           5.5         22           2
 I isoleucine          5.0         20           2
 K lysine              6.3         25           4
 L leucine             5.3         21           1
 M methionine          3.8         15           2
 N asparagine          3.3         13           2
 P proline            12.0         48           2
 Q glutamine           5.3         21           1
 R arginine            4.5         18           2
 S serine              9.0         36           2
 T threonine           4.0         16           2
 V valine              3.8         15           2
 W tryptophan          0.8          3           1
 Y tyrosine            4.0         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   lymphoid enhancer-binding factor 1 isoform 1 
LEF1                  0.912   lymphoid enhancer-binding factor 1 isoform 2 
LEF1                  0.887   lymphoid enhancer-binding factor 1 isoform 3 
TCF7L2                0.528   transcription factor 7-like 2 isoform 4 
TCF7L2                0.523   transcription factor 7-like 2 isoform 6 
TCF7L2                0.522   transcription factor 7-like 2 isoform 2 
TCF7L2                0.522   transcription factor 7-like 2 isoform 5 
TCF7L2                0.500   transcription factor 7-like 2 isoform 1 
TCF7L1                0.456   HMG-box transcription factor TCF-3 
TCF7L2                0.446   transcription factor 7-like 2 isoform 3 
TCF7                  0.325   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.256   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.256   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.255   transcription factor 7 (T-cell specific, HMG-box) 5...
TCF7                  0.255   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.255   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.252   transcription factor 7 (T-cell specific, HMG-box) 6...
CIC                   0.054   capicua homolog 
SOX6                  0.048   SRY (sex determining region Y)-box 6 isoform 4 [Hom...
SOX6                  0.048   SRY (sex determining region Y)-box 6 isoform 3 [Hom...
SOX6                  0.048   SRY (sex determining region Y)-box 6 isoform 1 [Homo...
SOX6                  0.048   SRY (sex determining region Y)-box 6 isoform 2 [Homo...
SOX30                 0.044   SRY (sex determining region Y)-box 30 isoform b [Homo...
SOX30                 0.044   SRY (sex determining region Y)-box 30 isoform a [Hom...
SOX5                  0.042   SRY (sex determining region Y)-box 5 isoform c [Homo...
SOX5                  0.042   SRY (sex determining region Y)-box 5 isoform b [Homo...
SOX5                  0.042   SRY (sex determining region Y)-box 5 isoform a [Homo...
SOX13                 0.040   SRY-box 13 
SOX11                 0.039   SRY-box 11 
SOX7                  0.037   SRY-box 7 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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