Guide to the Human Genome
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Name: LEF1 Sequence: fasta or formatted (386aa) NCBI GI: 195222734
Description:

lymphoid enhancer-binding factor 1 isoform 3

Referenced in:

SOX Family
T cells

Other entries for this name:
alt prot [371aa] lymphoid enhancer-binding factor 1 isoform 2
alt prot [399aa] lymphoid enhancer-binding factor 1 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         24           2
 C cysteine            1.0          4           1
 D aspartate           4.4         17           2
 E glutamate           7.5         29           3
 F phenylalanine       1.8          7           1
 G glycine             8.3         32           8
 H histidine           5.7         22           2
 I isoleucine          4.7         18           2
 K lysine              7.3         28           4
 L leucine             5.7         22           2
 M methionine          3.6         14           2
 N asparagine          3.4         13           2
 P proline            11.9         46           2
 Q glutamine           4.7         18           1
 R arginine            4.1         16           2
 S serine              8.5         33           2
 T threonine           3.6         14           2
 V valine              3.4         13           2
 W tryptophan          0.8          3           1
 Y tyrosine            3.4         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   lymphoid enhancer-binding factor 1 isoform 3 
LEF1                  0.934   lymphoid enhancer-binding factor 1 isoform 2 
LEF1                  0.915   lymphoid enhancer-binding factor 1 isoform 1 
TCF7L2                0.494   transcription factor 7-like 2 isoform 6 
TCF7L2                0.483   transcription factor 7-like 2 isoform 4 
TCF7L2                0.469   transcription factor 7-like 2 isoform 2 
TCF7L2                0.469   transcription factor 7-like 2 isoform 5 
TCF7L2                0.448   transcription factor 7-like 2 isoform 1 
TCF7L1                0.424   HMG-box transcription factor TCF-3 
TCF7L2                0.415   transcription factor 7-like 2 isoform 3 
TCF7                  0.379   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.308   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.308   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.277   transcription factor 7 (T-cell specific, HMG-box) 6...
TCF7                  0.277   transcription factor 7 (T-cell specific, HMG-box) 5...
TCF7                  0.277   transcription factor 7 (T-cell specific, HMG-box) is...
TCF7                  0.277   transcription factor 7 (T-cell specific, HMG-box) is...
CIC                   0.064   capicua homolog 
SOX6                  0.049   SRY (sex determining region Y)-box 6 isoform 4 [Hom...
SOX6                  0.049   SRY (sex determining region Y)-box 6 isoform 3 [Hom...
SOX6                  0.049   SRY (sex determining region Y)-box 6 isoform 1 [Homo...
SOX6                  0.049   SRY (sex determining region Y)-box 6 isoform 2 [Homo...
SOX5                  0.048   SRY (sex determining region Y)-box 5 isoform c [Homo...
SOX5                  0.048   SRY (sex determining region Y)-box 5 isoform b [Homo...
SOX5                  0.048   SRY (sex determining region Y)-box 5 isoform a [Homo...
SOX30                 0.046   SRY (sex determining region Y)-box 30 isoform b [Homo...
SOX30                 0.046   SRY (sex determining region Y)-box 30 isoform a [Hom...
SOX13                 0.043   SRY-box 13 
SOX7                  0.038   SRY-box 7 
SOX12                 0.038   SRY (sex determining region Y)-box 12 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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