BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo sapiens] (1899 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 3900 0.0 gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 3858 0.0 gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 1267 0.0 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 439 e-122 gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 427 e-119 gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 382 e-105 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 353 9e-97 gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s... 333 9e-91 gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 296 2e-79 gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 296 2e-79 gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 291 5e-78 gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 289 2e-77 gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 281 3e-75 gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 281 6e-75 gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 278 5e-74 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 264 5e-70 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 259 1e-68 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 259 2e-68 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 254 4e-67 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 254 4e-67 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 254 4e-67 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 254 6e-67 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 253 1e-66 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 253 1e-66 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 253 1e-66 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 253 1e-66 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 253 1e-66 gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s... 253 1e-66 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 252 2e-66 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 252 3e-66 >gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo sapiens] Length = 1899 Score = 3900 bits (10113), Expect = 0.0 Identities = 1899/1899 (100%), Positives = 1899/1899 (100%) Query: 1 MRSRLPPALAALGAALLLSSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISR 60 MRSRLPPALAALGAALLLSSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISR Sbjct: 1 MRSRLPPALAALGAALLLSSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISR 60 Query: 61 IVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNF 120 IVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNF Sbjct: 61 IVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNF 120 Query: 121 IRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELK 180 IRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELK Sbjct: 121 IRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELK 180 Query: 181 MIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVS 240 MIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVS Sbjct: 181 MIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVS 240 Query: 241 WTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSE 300 WTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSE Sbjct: 241 WTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSE 300 Query: 301 PLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLG 360 PLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLG Sbjct: 301 PLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLG 360 Query: 361 PTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNV 420 PTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNV Sbjct: 361 PTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNV 420 Query: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESP 480 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESP Sbjct: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESP 480 Query: 481 PVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNG 540 PVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNG Sbjct: 481 PVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNG 540 Query: 541 DENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNA 600 DENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNA Sbjct: 541 DENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNA 600 Query: 601 TSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVS 660 TSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVS Sbjct: 601 TSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVS 660 Query: 661 SLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGG 720 SLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGG Sbjct: 661 SLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGG 720 Query: 721 PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYN 780 PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYN Sbjct: 721 PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYN 780 Query: 781 PTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNL 840 PTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNL Sbjct: 781 PTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNL 840 Query: 841 VALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVG 900 VALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVG Sbjct: 841 VALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVG 900 Query: 901 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHI 960 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHI Sbjct: 901 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHI 960 Query: 961 SDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNV 1020 SDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNV Sbjct: 961 SDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNV 1020 Query: 1021 YAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTR 1080 YAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTR Sbjct: 1021 YAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTR 1080 Query: 1081 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTP 1140 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTP Sbjct: 1081 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTP 1140 Query: 1141 PPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVS 1200 PPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVS Sbjct: 1141 PPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVS 1200 Query: 1201 FVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKN 1260 FVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKN Sbjct: 1201 FVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKN 1260 Query: 1261 VPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVD 1320 VPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVD Sbjct: 1261 VPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVD 1320 Query: 1321 DFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLES 1380 DFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLES Sbjct: 1321 DFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLES 1380 Query: 1381 GSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDY 1440 GSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDY Sbjct: 1381 GSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDY 1440 Query: 1441 KPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYI 1500 KPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYI Sbjct: 1441 KPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYI 1500 Query: 1501 DCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIP 1560 DCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIP Sbjct: 1501 DCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIP 1560 Query: 1561 SRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP 1620 SRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP Sbjct: 1561 SRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP 1620 Query: 1621 PGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 1680 PGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT Sbjct: 1621 PGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 1680 Query: 1681 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 1740 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM Sbjct: 1681 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 1740 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR 1800 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR Sbjct: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR 1800 Query: 1801 PGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPG 1860 PGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPG Sbjct: 1801 PGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPG 1860 Query: 1861 PPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG 1899 PPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG Sbjct: 1861 PPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG 1899 >gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo sapiens] Length = 3063 Score = 3858 bits (10006), Expect = 0.0 Identities = 1876/1879 (99%), Positives = 1877/1879 (99%) Query: 21 IEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS 80 I + GMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS Sbjct: 1185 ILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS 1244 Query: 81 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 140 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG Sbjct: 1245 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304 Query: 141 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 200 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL Sbjct: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364 Query: 201 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG 260 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG Sbjct: 1365 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG 1424 Query: 261 GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD 320 GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD Sbjct: 1425 GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD 1484 Query: 321 VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 380 VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT Sbjct: 1485 VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 1544 Query: 381 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 440 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE Sbjct: 1545 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 1604 Query: 441 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT 500 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT Sbjct: 1605 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT 1664 Query: 501 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI 560 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI Sbjct: 1665 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI 1724 Query: 561 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 620 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR Sbjct: 1725 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 1784 Query: 621 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL Sbjct: 1785 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844 Query: 681 NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 740 NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ Sbjct: 1845 NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 1904 Query: 741 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY 800 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY Sbjct: 1905 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY 1964 Query: 801 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP 860 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP Sbjct: 1965 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP 2024 Query: 861 RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP 920 RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP Sbjct: 2025 RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP 2084 Query: 921 LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL 980 LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL Sbjct: 2085 LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144 Query: 981 GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY 1040 GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY Sbjct: 2145 GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY 2204 Query: 1041 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP 1100 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP Sbjct: 2205 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP 2264 Query: 1101 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI 1160 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI Sbjct: 2265 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI 2324 Query: 1161 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK 1220 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK Sbjct: 2325 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK 2384 Query: 1221 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA 1280 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA Sbjct: 2385 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA 2444 Query: 1281 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA 1340 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA Sbjct: 2445 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA 2504 Query: 1341 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP 1400 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP Sbjct: 2505 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP 2564 Query: 1401 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK 1460 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK Sbjct: 2565 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK 2624 Query: 1461 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG 1520 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG Sbjct: 2625 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG 2684 Query: 1521 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD 1580 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD Sbjct: 2685 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD 2744 Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE Sbjct: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS Sbjct: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 Query: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 1760 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN Sbjct: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924 Query: 1761 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG 1820 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG Sbjct: 2925 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG 2984 Query: 1821 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC 1880 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC Sbjct: 2985 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC 3044 Query: 1881 DSSQCASIPYNGQGYPGSG 1899 DSSQCASIPYNGQGYPGSG Sbjct: 3045 DSSQCASIPYNGQGYPGSG 3063 Score = 490 bits (1262), Expect = e-138 Identities = 336/1084 (30%), Positives = 527/1084 (48%), Gaps = 70/1084 (6%) Query: 22 EAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSG 81 + E +C A D+V LVDGSWS+GR NF+ + FI+ +V FDIG ++ ++ + QYS Sbjct: 127 KTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSS 186 Query: 82 DPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGV 141 D RTE+ LN + + LL A+ +PYKGGNT+TG A++++ + F AG R K+ + Sbjct: 187 DTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAI 246 Query: 142 LITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLS 201 +ITDGKSQD+VE P+++L++ GVE+F++GIK AD ELK IA+ P H +NVA+F+++ Sbjct: 247 IITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIV 306 Query: 202 RIVDDLTINLCNS--------VKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKV 253 I +++ +C+ V G +E PSNL+ E + + +++W P V YKV Sbjct: 307 DIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKV 366 Query: 254 EYYPVSGGKRQEFYVSRMETSTV-LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP 312 P++ G RQ +T+T+ ++DL +TEY ++V ++ SEP+ EKT P+ Sbjct: 367 ILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMK 426 Query: 313 VVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLV 372 V + + + G + I ++ V+ K + P + L Sbjct: 427 -VQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYS 485 Query: 373 --PNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK-V 429 P+TE+ + + D+ E + T P + +T+ +F VP K Sbjct: 486 RDPHTEFTLKKFTKVEDII-EAIN----TFPYRGGSTNTGKAMTYVREKIF---VPSKGS 537 Query: 430 RKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE---SPPVTAQ- 485 R + + D K + R + + L++ + AV E E SPP Sbjct: 538 RSNVPKVMILITDGKSSDAFR-DPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHV 596 Query: 486 --------------ETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLY--RITWAPFG 529 E T+ + ++ + + + D S+V+ Y + W+P G Sbjct: 597 FTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAG 656 Query: 530 SS--------------DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 575 + D++ + ++V +L P T+Y V++TA Y D S L G Sbjct: 657 ENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYED-GFSIPLAG 715 Query: 576 SERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 635 E TT+ K PRNL+V + T++S + W A GRV +YRI Y+P G G + Sbjct: 716 EE------TTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAG-GESREV 768 Query: 636 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL-NTVRNLRVYDPSTS 694 T Q L+ L PDT Y ++V Y G G +TG T+ + R+LRV DP+TS Sbjct: 769 TTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTS 828 Query: 695 TLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 754 T+ + W A G +QY + Y P AGG + V + G+T +L+ L+ T Y ++V +Y Sbjct: 829 TMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYA 888 Query: 755 EGDGGRTSDTGRTL-MRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 813 G G G TL RG +++ + T S+ W APG V YRV + + + Sbjct: 889 SGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDT 948 Query: 814 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 873 +P + +E L P+T Y +++ A YS GEG P T + L+V ET Sbjct: 949 GEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEET 1008 Query: 874 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 933 N++ V W A G V YR++Y P G VP + +L+ LQP T Y ITV+ Sbjct: 1009 ENTMRVTWKPAPGKVVNYRVVYRPH-GRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLP 1067 Query: 934 VYEDGDGGHLTGNGRTVG-LLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSN 992 +Y+ G+G G+G T P+N+ SD + FRV+W+P+P V GYK+ + P G + Sbjct: 1068 IYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDD 1127 Query: 993 EPM-EAFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQ 1050 + E VG + L L TTY VNV+ +D G S PL Q T + T + Sbjct: 1128 RRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILS 1187 Query: 1051 IGWD 1054 G + Sbjct: 1188 SGME 1191 Score = 426 bits (1094), Expect = e-118 Identities = 326/1094 (29%), Positives = 512/1094 (46%), Gaps = 61/1094 (5%) Query: 283 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYIL 341 + E + V S V+++ E + G E + P +L +V + + W P TGY + Sbjct: 309 QNEIISQVCSGVDEQLGELVSGEE--VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKV 366 Query: 342 SYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLP 401 P+ T +R + +GP + + DL +TEY ++V A+ +SEP+++ E T P Sbjct: 367 ILTPM--TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424 Query: 402 LP------RPQDLK-----LRDVTHST-------MNVFWEPV-------PGKVRKYIVRY 436 + R D+K L D ++S + F E + P +V+ +V+Y Sbjct: 425 MKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQY 484 Query: 437 -KTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVS-AVHDEGESPPVTAQETTRPVPAP 494 + P + + + E + F + + A+ E V ++ + VP Sbjct: 485 SRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKV 544 Query: 495 TNLKITEVTSEGFRG-TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPN 553 L +S+ FR SDV ++ + S+ +E I + T VF + + Sbjct: 545 MILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSE-LEAIASPPAETHVFTVEDFD 603 Query: 554 TIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPAS 613 +S E + E+ L + +A P++L TS W PA Sbjct: 604 AFQRISF------ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAG 656 Query: 614 GRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTG 673 V Y ITY+ + G+ +E T SVVL LKP+T Y + V++ Y DG + G Sbjct: 657 ENVFSYHITYKEAAGD-DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAG 715 Query: 674 RGKTKPLNTV-RNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTN 732 T+ + RNL+V D +T + + W A G +Y++ Y P AGG V P N Sbjct: 716 EETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR 775 Query: 733 YAILRNLQPDTSYTVTVVPVYTEGDGGR-TSDTGRTLMRGLARNVQVYNPTPNSLDVRWD 791 L NL PDT Y V+V+P Y G G T + +RG R+++V +PT +++ + W Sbjct: 776 RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWS 835 Query: 792 PAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNP 851 APG V QY V Y+PV G E + V G+T L+ L T Y++++ ALY+ G G+ Sbjct: 836 GAPGKVKQYLVTYTPVAGGETQE-VTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDA 894 Query: 852 SPAQGRTLPRSG-PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP 910 +G TL G P++L T S+ W A G V+ YR+ + D +P Sbjct: 895 LFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLP 954 Query: 911 GRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRV 970 + +++ LQP+T Y+I+V A Y G+G LTG+ T + + + +E RV Sbjct: 955 EDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRV 1014 Query: 971 SWDPSPSPVLGYKIVYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLS 1029 +W P+P V+ Y++VY+P G + M A V +TS L L P TTYD+ V Y G Sbjct: 1015 TWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEG 1074 Query: 1030 VPLTDQGTTL--YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSP-ADGTRGQEIT 1085 GTT + + +LKT +F V W P Y++ P D R E+ Sbjct: 1075 KLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELV 1134 Query: 1086 VRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPT 1145 V + + L T Y V VF E + +E TT+ T P Sbjct: 1135 VGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTV---------MPI 1185 Query: 1146 IPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYS 1205 + + A+ADIV L D SWSIG NF V FI V FD I P +Q++ QYS Sbjct: 1186 LSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFD-IGPKRVQIALAQYS 1244 Query: 1206 DEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVL 1265 + ++E++LN + DK L A+ N+ Y+GGNT TG AL FI+++ ++GMR K+ Sbjct: 1245 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304 Query: 1266 VVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESF 1325 V++TDG+SQD+V+ + ++ G +F +G+ + D EL IA+ P + H + V DFES Sbjct: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364 Query: 1326 EKIEDNLITFVCET 1339 +I D+L +C + Sbjct: 1365 SRIVDDLTINLCNS 1378 Score = 171 bits (434), Expect = 5e-42 Identities = 122/370 (32%), Positives = 182/370 (49%), Gaps = 28/370 (7%) Query: 1058 VKWSPHRA-ATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNL 1115 + W+P + T Y++ L+P G+R ++V T+ LS DT+Y ++V Sbjct: 352 LNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMT 411 Query: 1116 EGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNF 1175 +S+ E T P + +R V KADIVFL D S+SIG NF Sbjct: 412 SSEPISIMEKTQ-------------PMKVQVECSRGV--DIKADIVFLVDGSYSIGIANF 456 Query: 1176 NKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGG 1235 KV F+ V F EISP +Q+S VQYS + +EF L + + A+ YRGG Sbjct: 457 VKVRAFLEVLVKSF-EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGG 515 Query: 1236 NTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVG 1295 +T TGKA+T+++EK+ G R NVPKV++++TDG+S D + A+ ++ S +F VG Sbjct: 516 STNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVG 575 Query: 1296 VADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSP 1355 V D +EL IAS P+E HVF V+DF++F++I L +C I Y P Sbjct: 576 VKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPP 635 Query: 1356 GFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTI 1415 K L +T F + + E+ +S + K A + + P S T Sbjct: 636 --KDLSFSEVTSYGFKTNWSPAGEN----VFSYHITYKEAAGDDEVTVVE----PASSTS 685 Query: 1416 ILLFRLLPET 1425 ++L L PET Sbjct: 686 VVLSSLKPET 695 Score = 162 bits (411), Expect = 2e-39 Identities = 103/295 (34%), Positives = 154/295 (52%), Gaps = 7/295 (2%) Query: 1044 TDLKTYQIGWDTFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDT 1102 +DL I +T + W+ P YR+ + P +E T+ S T + L P+T Sbjct: 29 SDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPET 88 Query: 1103 DYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVF 1162 +Y VT+ E V V T++ T + T+P P T + A D+VF Sbjct: 89 EYVVTITSYDEVEES--VPVIGQLTIQ-TGSSTKPVEKKPGKT--EIQKCSVSAWTDLVF 143 Query: 1163 LTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKAL 1222 L D SWS+G +NF ++ FI V FD I +V VQYS + ++EF LN Y + Sbjct: 144 LVDGSWSVGRNNFKYILDFIAALVSAFD-IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDE 202 Query: 1223 ALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAAL 1282 L A++ I Y+GGNT TG A+ ++ + T +G R PKV +++TDG+SQDEV+ A Sbjct: 203 LLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPAR 262 Query: 1283 VIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVC 1337 ++ G VF +G+ D EL IAS PS HVF V +F++ I++ +I+ VC Sbjct: 263 ELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVC 317 Score = 57.8 bits (138), Expect = 1e-07 Identities = 30/85 (35%), Positives = 46/85 (54%) Query: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279 +++ PS+L + +SW P D + Y++ P + G +EF +S T T+L + Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 Query: 280 LKPETEYVVNVYSVVEDEYSEPLKG 304 L PETEYVV + S E E S P+ G Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIG 108 Score = 46.6 bits (109), Expect = 2e-04 Identities = 24/24 (100%), Positives = 24/24 (100%) Query: 1 MRSRLPPALAALGAALLLSSIEAE 24 MRSRLPPALAALGAALLLSSIEAE Sbjct: 1 MRSRLPPALAALGAALLLSSIEAE 24 Score = 44.7 bits (104), Expect = 9e-04 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 6/85 (7%) Query: 312 PVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTD 370 P LN + T+H+ W +PV GY ++ P D PT KE L + + L++ Sbjct: 27 PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDG-PT--KEFTLSASTTETLLSE 83 Query: 371 LVPNTEYAVTVQAVLHDLTSEPVTV 395 LVP TEY VT+ + +D E V V Sbjct: 84 LVPETEYVVTITS--YDEVEESVPV 106 Score = 37.7 bits (86), Expect = 0.11 Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 1/82 (1%) Query: 580 LPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGG 639 L + + +A P +L N++ + W + YRIT P+T +G + T+ Sbjct: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 Query: 640 RQNSVVLQKLKPDTPYTITVSS 661 +L +L P+T Y +T++S Sbjct: 75 STTETLLSELVPETEYVVTITS 96 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 866 NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 925 N ++ E N++ ++W P+ YRI PT P E+ T+ +L L P+T Sbjct: 32 NFKIIDE--NTVHMSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPET 88 Query: 926 PYKITVIAVYE 936 Y +T+ + E Sbjct: 89 EYVVTITSYDE 99 Score = 34.3 bits (77), Expect = 1.2 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 1/85 (1%) Query: 954 PPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYT-LHNLNP 1012 PP +++ +SW P++GY+I P E + T+ T L L P Sbjct: 27 PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVP 86 Query: 1013 STTYDVNVYAQYDSGLSVPLTDQGT 1037 T Y V + + + SVP+ Q T Sbjct: 87 ETEYVVTITSYDEVEESVPVIGQLT 111 Score = 32.3 bits (72), Expect = 4.5 Identities = 26/116 (22%), Positives = 45/116 (38%), Gaps = 1/116 (0%) Query: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 550 V P++L + +W + YRIT P E L+ + L Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSEL 84 Query: 551 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLT 606 P T Y V+IT+ Y + ES +IG +T+ + P ++ + ++ T Sbjct: 85 VPETEYVVTITS-YDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 >gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] Length = 1796 Score = 1267 bits (3278), Expect = 0.0 Identities = 653/1459 (44%), Positives = 899/1459 (61%), Gaps = 54/1459 (3%) Query: 463 QTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYR 522 ++L S V ++ +A T P PT L +EVT+ F W H +V YR Sbjct: 328 ESLTRTLCSRVEEQDREIKASAHAITGP---PTELITSEVTARSFMVNWTHAPGNVEKYR 384 Query: 523 ITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPI 582 + + P E +++G ++ V +NL T Y++++ AIY + S+ L G+E TL + Sbjct: 385 VVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYA-HTASEGLRGTETTLAL 443 Query: 583 LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTG--EGNEQTTTIGGR 640 +L +Y+ T NS+ VKWD G Y I Y P T G+E+ IG Sbjct: 444 PMAS-------DLLLYDVTENSMRVKWDAVPG-ASGYLILYAPLTEGLAGDEKEMKIGET 495 Query: 641 QNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRW 700 + L L P+T YT+TV +++ + +TG+ T L+ RNLR+ + +++ + W Sbjct: 496 HTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTW 555 Query: 701 DHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGR 760 D Y++ Y A G V + T + L+ L P T YT+ + +Y EG Sbjct: 556 DPTSRQINGYRIVYNNADGTEINEVEVDPITTFP-LKGLTPLTEYTIAIFSIYDEGQSEP 614 Query: 761 TSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPG 820 + T + +++ T +S V W P +++++ PV G + E ++ Sbjct: 615 LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674 Query: 821 NTRMVHLERLIPDTLYSVNLVALYSDG-EGNPSPAQGRTLP------------------- 860 V +E L P T Y V+L+A+ DG E A G TL Sbjct: 675 QDSHV-IEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSV 733 Query: 861 -RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEY---TTVPGRRNNV 916 ++G RNL V ETT+SL V WD +D VQQ+R+ Y GDP +E VPG +NN+ Sbjct: 734 FQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNL 793 Query: 917 ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSP 976 +L+PL PDT YK+TV +Y DG+G ++ G+T+ PQN+ +S+EWY R R++WDP Sbjct: 794 LLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853 Query: 977 SPVLGYKIVYKPVGSNEP-MEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTD 1034 SPV GY+IVYKPV P +E FVG ++ + + NL Y+V ++A SG S LT Sbjct: 854 SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913 Query: 1035 QGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHC 1094 TL+L VT+L+ + + C W HR AT+YR+ + + QE TV G T HC Sbjct: 914 MVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHC 973 Query: 1095 FTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCK 1154 F GL PD++Y ++V+ + +EGP VS+ E T PT PT PPT IPPA++VCK Sbjct: 974 FYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPT------IPPAKEVCK 1027 Query: 1155 GAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKL 1214 AKAD+VF+ D SWSIGD+NFNK++ F+++TVG ++I G QV+ VQ++D+ ++EFKL Sbjct: 1028 AAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKL 1087 Query: 1215 NTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQ 1274 N Y K L A+++I Y+GGNT+TGKA+ ++++ + T ESG R+ +PKV+VV+TDGRSQ Sbjct: 1088 NAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQ 1147 Query: 1275 DEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLIT 1334 D+V K + +Q G+S+F +GVAD DY+EL +I SKPS RHVF VDDF++F+KIED LIT Sbjct: 1148 DDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELIT 1207 Query: 1335 FVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKN 1394 FVCETA+++CP+++ DG GFKM+E + L EK+F+SV+GVS+E G+F + Y++ K+ Sbjct: 1208 FVCETASATCPVVHKDGIDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNVFPCYQLHKD 1267 Query: 1395 AFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKT 1454 A V+QPT LHP GLP YTI LFR+LP+TP +PFA+W+I +++ P VGVI D KT Sbjct: 1268 ALVSQPTRYLHPEGLPSDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNGGKT 1327 Query: 1455 LSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAG 1514 L++FN D G+ QTVTF+ E++ +FYGSFHK+HIVV+ VK+ IDC ++ EK + + Sbjct: 1328 LTYFNYDQSGDFQTVTFEGPEIRKIFYGSFHKLHIVVSETLVKVVIDCKQVGEKAMNASA 1387 Query: 1515 NITTDGYEILGKLLKGE---RKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAF 1571 NIT+DG E+LGK+++ SA FQ+Q FDIVCS W + D+CC++P RD+ CP Sbjct: 1388 NITSDGVEVLGKMVRSRGPGGNSAPFQLQMFDIVCSTSWANTDKCCELPGLRDDESCPDL 1447 Query: 1572 PNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 1631 P+SC+C++ + GP GP GGPG +GP+G++G G GP GPRG+IG PGPQGPPGPQG Sbjct: 1448 PHSCSCSETNEVALGPAGPPGGPGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQGPPGPQG 1507 Query: 1632 PNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP 1691 P+GLSI G G G KG+ G+ GLPG G PG G PG G PG RG GKDG+ GP GP Sbjct: 1508 PSGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPGRDGSPGQRGLPGKDGSSGPPGP 1567 Query: 1692 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 1751 PGP G PG+PGV G +G G G G PG G KGE+G+RGD+ SQ M+R+VARQVCEQL Sbjct: 1568 PGPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERGERGDLQSQAMVRSVARQVCEQL 1627 Query: 1752 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG 1811 I M R+ +LNQIP+ S R GPPG PG PGS GA GE GP G PGFPG G+ G Sbjct: 1628 IQSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPG 1687 Query: 1812 PPGERGLPGEKGER---GTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNS 1868 PGERGL G KGE+ G G+ GPRG PGP GP GESR G PG GS GP GPPG G Sbjct: 1688 TPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVP 1747 Query: 1869 GIRGPPGPPGYCDSSQCAS 1887 G +GP G PGYCD S C++ Sbjct: 1748 GPQGPSGQPGYCDPSSCSA 1766 Score = 590 bits (1522), Expect = e-168 Identities = 342/859 (39%), Positives = 501/859 (58%), Gaps = 32/859 (3%) Query: 19 SSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQ 78 SS E C T A ADIV+LVDGSWSIGR NFR VR F+ +V FD+G ++ +I LAQ Sbjct: 142 SSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQ 201 Query: 79 YSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARK 138 YSGDPR EW LNA K +++AV NLPYKGGNTLTG+ALN+I + +F+ +AG R K Sbjct: 202 YSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSK 261 Query: 139 IGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFE 198 IG+LITDGKSQDD+ PS+ L++ GVELFAIG+KNAD EL+ IA++PD TH YNVA+F+ Sbjct: 262 IGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFD 321 Query: 199 SLSRIVDDLTINLCNSVKGPG-DLEA--------PSNLVISERTHRSFRVSWTPPSDSVD 249 + +V+ LT LC+ V+ +++A P+ L+ SE T RSF V+WT +V+ Sbjct: 322 LMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVE 381 Query: 250 RYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTL 309 +Y+V YYP GGK E V +STVLK+L TEY + V+++ SE L+GTE TL Sbjct: 382 KYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTL 441 Query: 310 PVPVVS-LNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQL 368 +P+ S L +YDV +M V+W V GA+GY++ Y P+ + KE+++G T D++L Sbjct: 442 ALPMASDLLLYDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIEL 501 Query: 369 TDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK 428 + L+PNTEY VTV A+ + S+PVT +E TL L P++L++ +V ++ + W+P + Sbjct: 502 SGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQ 561 Query: 429 VRKYIVRYKTPE-EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQET 487 + Y + Y + ++ EVEVD T+ LK L T YT+++ +++DEG+S P+T T Sbjct: 562 INGYRIVYNNADGTEINEVEVD-PITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFT 620 Query: 488 TRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVF 547 T VPA L+I EVT++ FR TW ++D L+++ W P E +L ++++ V Sbjct: 621 TEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVI 680 Query: 548 ENLNPNTIYEVSITAIYPDESESDDLIGSERTL------PILT-------TQAPKSGPRN 594 E L P T YEVS+ A+ D SES+ + TL P T T ++G RN Sbjct: 681 EGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRN 740 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQ---TTTIGGRQNSVVLQKLKP 651 L V + T++SL VKWD + VQ++R+TY + G+ E+ T + G QN+++L+ L P Sbjct: 741 LVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLP 800 Query: 652 DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 711 DT Y +TV+ +Y DGEG ++ GKT P + +NLRV + + L + WD + Y+ Sbjct: 801 DTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYR 860 Query: 712 LFYAP-AAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 770 + Y P + GP + + N ++ NL Y V + G + +TL Sbjct: 861 IVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFL 920 Query: 771 GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 830 G+ N+Q + SL W YRVV + + ES V G TR L Sbjct: 921 GVT-NLQAKHVEMTSLCAHWQ-VHRHATAYRVVIESLQDRQKQESTVGGGTTRHC-FYGL 977 Query: 831 IPDTLYSVNLVALYSDGEG 849 PD+ Y +++ + EG Sbjct: 978 QPDSEYKISVYTKLQEIEG 996 Score = 158 bits (399), Expect = 5e-38 Identities = 79/189 (41%), Positives = 122/189 (64%), Gaps = 1/189 (0%) Query: 27 ECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFD-IGPKRVQIALAQYSGDPRT 85 E A+AD+V +VDGSWSIG NF + SF+ V + IG Q+A+ Q++ DPRT Sbjct: 1024 EVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRT 1083 Query: 86 EWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITD 145 E++LNA++ K++LL A+ ++ YKGGNT TG A+ ++R F ++G R K+ V+ITD Sbjct: 1084 EFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITD 1143 Query: 146 GKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVD 205 G+SQDDV S++++ +G +FAIG+ +AD EL I + P H + V DF++ +I D Sbjct: 1144 GRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIED 1203 Query: 206 DLTINLCNS 214 +L +C + Sbjct: 1204 ELITFVCET 1212 Score = 156 bits (394), Expect = 2e-37 Identities = 95/309 (30%), Positives = 154/309 (49%), Gaps = 15/309 (4%) Query: 1037 TTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFT 1096 T L NV + QI W +P Y+L ++P G + ++ ++ + T Sbjct: 34 TRLRYNVISHDSIQISWK------APRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQ 87 Query: 1097 GLSPDTDYGVTVFVQTPNLEGPGVS-------VKEHTTVKPTEAPTEPPTPPPPPTIPPA 1149 GL PD +Y V + + E +++ KP + P + Sbjct: 88 GLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEV 147 Query: 1150 RDVCKG-AKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEV 1208 + VC+ A ADIV L D SWSIG NF V F+ N V FD + ++ QYS + Sbjct: 148 KFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFD-VGSEKTRIGLAQYSGDP 206 Query: 1209 KSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVV 1268 + E+ LN ++ K + A++N+ Y+GGNT TG AL +I E E+G R V K+ +++ Sbjct: 207 RIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILI 266 Query: 1269 TDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKI 1328 TDG+SQD++ + +++SG +F +GV + D NEL IAS+P HV+ V +F+ + Sbjct: 267 TDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTV 326 Query: 1329 EDNLITFVC 1337 ++L +C Sbjct: 327 VESLTRTLC 335 Score = 54.7 bits (130), Expect = 9e-07 Identities = 31/64 (48%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Query: 1578 TQDSVGPPGPPGPAGG--PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 1635 TQ GPPGP GP+G PG+ GP G G GPPG G GP GP G PG P+ Sbjct: 1708 TQGPRGPPGPAGPSGESRPGSPGPPGS---PGPRGPPGHLGVPGPQGPSGQPGYCDPSSC 1764 Query: 1636 SIPG 1639 S G Sbjct: 1765 SAYG 1768 Score = 53.1 bits (126), Expect = 2e-06 Identities = 24/86 (27%), Positives = 43/86 (50%) Query: 219 GDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLK 278 G + P+ L + +H S ++SW P YK+ P SGGK + + T +++ Sbjct: 28 GQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQ 87 Query: 279 DLKPETEYVVNVYSVVEDEYSEPLKG 304 L P+ Y V + + +D+ S+P +G Sbjct: 88 GLMPDQNYTVQIIAYNKDKESKPAQG 113 Score = 39.3 bits (90), Expect = 0.037 Identities = 17/59 (28%), Positives = 28/59 (47%) Query: 692 STSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750 S ++ + W G YKL P +GG + + AI++ L PD +YTV ++ Sbjct: 42 SHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQII 100 Score = 37.7 bits (86), Expect = 0.11 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Query: 855 QGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRN 914 QG+ P P LR + +S+ ++W G Y+++ +PT G ++ + Sbjct: 27 QGQVAP---PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTAT 82 Query: 915 NVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGR 948 I+Q L PD Y + +IA +D + G R Sbjct: 83 KAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFR 116 Score = 37.4 bits (85), Expect = 0.14 Identities = 21/95 (22%), Positives = 40/95 (42%), Gaps = 1/95 (1%) Query: 586 QAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVV 645 Q + P L+ + +S+ + W G+ Y++ P++G G + + Sbjct: 27 QGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAI 85 Query: 646 LQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680 +Q L PD YT+ + + D E G+ + K L Sbjct: 86 IQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDL 120 Score = 35.8 bits (81), Expect = 0.41 Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Query: 784 NSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVAL 843 +S+ + W G Y+++ +P G + ++ + T+ + ++ L+PD Y+V ++A Sbjct: 44 DSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAI-IQGLMPDQNYTVQIIAY 102 Query: 844 YSDGEGNPSPAQGR 857 D E P+ Q R Sbjct: 103 NKDKESKPAQGQFR 116 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 439 bits (1129), Expect = e-122 Identities = 277/771 (35%), Positives = 385/771 (49%), Gaps = 67/771 (8%) Query: 1153 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 1212 CK D+VFL D S S+G ++F KV +++ N V F E+ P +V V+YSD + F Sbjct: 32 CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTF-EVGPDRTRVGVVRYSDRPTTAF 90 Query: 1213 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 1269 +L + + A + + Y GGNT TG AL +I + + +G R + +V +++T Sbjct: 91 ELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLT 150 Query: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 1329 DGRSQD V AA ++G +F VGV + EL IAS+P HVF V DF + +KI Sbjct: 151 DGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIR 210 Query: 1330 DNLITFVCETATSSCPLIYLDG----YTSPGFKMLEAYNLTEKNFASVQGV--SLESGSF 1383 L +CE CP + ++G +T+ G K + ++L + SV+ + E+G+ Sbjct: 211 GKLRRRLCENVL--CPSVRVEGDRFKHTNGGTKEITGFDLMD--LFSVKEILGKRENGAQ 266 Query: 1384 PSYSAYRIQKNAF-VNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKP 1442 SY ++ +F V Q T D+ P GLP Y + FR + + + IWQ+ D+ P Sbjct: 267 SSY----VRMGSFPVVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIP 322 Query: 1443 QVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDC 1502 QV + D +K + + + V F V LF +HK+ + + +++V ++IDC Sbjct: 323 QVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDC 382 Query: 1503 YEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSR 1562 + I+E NI G ++GK L + F +Q I C + CCDIPS Sbjct: 383 ALVQTLPIEERENIDIQGKTVIGKRLY-DSVPIDFDLQRIVIYCDSRHAELETCCDIPS- 440 Query: 1563 RDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAK--------------GPRGERGISGA 1608 G C PP PP PG++ G +GE G++G Sbjct: 441 ---GPCQV------TVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGP 491 Query: 1609 IGPPGPRGDIGPPGPQGPPGPQGPNG-LSI-PGEQGRQGMKGDAGEPGLPGRTGTPGLPG 1666 +G PGP+GDIG GP G PGP+G G + I P QG +G KG G PG PGR G+ G+ G Sbjct: 492 MGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRG 551 Query: 1667 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGK---------------PG 1711 PG +G PG G G G GP G PGPPG G+PG+ G G+ PG Sbjct: 552 EPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPG 611 Query: 1712 KPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPN 1768 KPGD GRPGPSG+ G +G++GD+ V ++ + G+ +Q Sbjct: 612 KPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671 Query: 1769 DYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT- 1827 +R GP G GPPG G RG+ G G PG PG G+QGPPG G+PG G G+ Sbjct: 672 GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731 Query: 1828 GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G G G PG PGP G TGPPG G GPPGPPG G G RG G PG Sbjct: 732 GLPGEIGFPGKPGPPGP--TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780 Score = 264 bits (675), Expect = 5e-70 Identities = 154/345 (44%), Positives = 181/345 (52%), Gaps = 47/345 (13%) Query: 1583 GPPGPPGPAGGPGAKGPRGERG---ISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IP 1638 GPPG G G GA GPRGE G + G G PG GD GP GPQGP GP+GP G + P Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332 Query: 1639 GEQGRQGMKGDAGEPGLPGRTGTPGLPG---PPGPMGPPGDRGFTGKDGA---------- 1685 G G G G G+ G G G+PGLPG P GP G PG++G GK+G Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392 Query: 1686 --------MGPRGPPGPPGSPGSPGVTG---------PSGKPGKPGDHGRPGPSGLKGEK 1728 G +GPPG G PG PG+ G P G PG+ G G PGP G G Sbjct: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 1452 Query: 1729 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-QSSRNQPGPPGPPGP-- 1785 G RG+ S +R R + E+L R +L Q+P Y +SS+ +PGPPGPPG Sbjct: 1453 GLRGESPSMETLR---RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509 Query: 1786 -PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTG---SSGPRGLPGPPGP 1841 PG AG GEPG G+ G G G GP GERG G+ G G G GP G+PG PG Sbjct: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569 Query: 1842 QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 1886 G ++ G PG G +G GP G PG + GPPGPPG CD SQCA Sbjct: 1570 PGYAKDGLPGIPGPQGETGPAGHPG---LPGPPGPPGQCDPSQCA 1611 Score = 247 bits (630), Expect = 9e-65 Identities = 142/314 (45%), Positives = 164/314 (52%), Gaps = 67/314 (21%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIPGEQ 1641 G PG PG G PG GP G GI+GA GPPG +G PG +GPPGPQGP+GL IPGE+ Sbjct: 1186 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGLPGIPGEE 1242 Query: 1642 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------PGPP 1695 G++G G G PG PG+ G PGLPGP G GPPG +G TG GA GPRG PG Sbjct: 1243 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 1302 Query: 1696 GSPGSPGVTGPS------------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 G PG G TGP+ GK G PG G PGPSG G+KG +G+ S + Sbjct: 1303 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---- 1358 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 1803 PG GP GPPG G +G PG G PG Sbjct: 1359 ---------------------------------PGFLGPRGPPGEPGEKGVPGKEGVPGK 1385 Query: 1804 PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGP 1858 PG PG + GERG PG KG++G G G G PG PG +G + G PG G GP Sbjct: 1386 PGEPGFK---GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 1442 Query: 1859 PGPPGRPGNSGIRG 1872 PGPPG+PG G+RG Sbjct: 1443 PGPPGQPGFPGLRG 1456 Score = 238 bits (608), Expect = 3e-62 Identities = 143/330 (43%), Positives = 165/330 (50%), Gaps = 35/330 (10%) Query: 1584 PPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQG 1642 PPGPPG G PG KG +G G G G G +G+ GPPG GPPG GP G G G Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGP------MGPPGDRGFTGKDGAMGPRGPPGPPG 1696 G KGD G PG+PG G PG PGPPG GPPG +G GK+G GP+GP G PG Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237 Query: 1697 SPGSPGVTGPSGKPGKPGD---HGRP---------GPSGLKGEKGDRGDIASQNMMRAVA 1744 PG G G GKPG PG+ G P GP G KG GD G + A+ Sbjct: 1238 IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 1297 Query: 1745 RQVCEQL-----ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGG 1799 E L +G + P S PG PGP G PG G++GE G G Sbjct: 1298 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357 Query: 1800 RPGF------PGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE-SRTG 1848 PGF PG PG +G PG+ G+PG+ GE G G G +G GPPG +G+ G Sbjct: 1358 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG 1417 Query: 1849 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 PG G G GP G PG +G GPPGPPG Sbjct: 1418 IPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447 Score = 235 bits (600), Expect = 3e-61 Identities = 143/341 (41%), Positives = 167/341 (48%), Gaps = 45/341 (13%) Query: 1576 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAI----------GPPGPRGDIGPPGPQG 1625 T Q GP G GP G G GP G G+ G++ G PGPRG G PGP G Sbjct: 616 TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675 Query: 1626 PPGPQGPNGLS-IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG 1684 GP GP G PG QG +G KGD G PG+PG G G PGPPG GPPG G G G Sbjct: 676 ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPG 735 Query: 1685 AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP---GPSGLKGEKGDRGDIASQNMMR 1741 +G G PGPPG G PG GP+G PG PG G P G GL G+ G RG+I Q + Sbjct: 736 EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG 795 Query: 1742 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 1801 + E + G F + + + + + G G PG G G +GE GP G P Sbjct: 796 RPGEK-GEAGLPGAPG-FPGVRGE-----KGDQGEKGELGLPGLKGDRGEKGEAGPAGPP 848 Query: 1802 GFPGT----------PGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE--- 1844 G PGT PG QGP GE+G PG GE G G GP+G GPPG +G+ Sbjct: 849 GLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGA 908 Query: 1845 -------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G PG G+ GP GPPG G G+RG PG G Sbjct: 909 HGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 949 Score = 229 bits (585), Expect = 1e-59 Identities = 144/365 (39%), Positives = 160/365 (43%), Gaps = 77/365 (21%) Query: 1569 PAFPNSCTCTQD-SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPP 1627 P P S D +G GPPGP+G PG KG G RG+ G GP GP G G PG G Sbjct: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER 1089 Query: 1628 GPQGPNGLSI----------------------PGEQGRQGMKGDAGEPGLPGRTGT---- 1661 GP G GLS PG G G KGD G PG PGR GT Sbjct: 1090 GPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKK 1149 Query: 1662 -----PGLPGPPGPMGPPGDRGFTGKDGA---------------MGPRGPPGPPGSPGSP 1701 PGLPGPPG GP G +G G DG MGP G PGPPG+ G Sbjct: 1150 GEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 1209 Query: 1702 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 1761 G GP G G PG G PGP G G G I G+ + + Sbjct: 1210 GAAGPPGIQGSPGKEGPPGPQGPSGLPG----------------------IPGEEGKEGR 1247 Query: 1762 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 1821 P +PG PGP G G G +G G G PG G G G PG+ GLPG+ Sbjct: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307 Query: 1822 KGERG-TGSSGPRGLPGPPGPQGE-------SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 1873 G+ G TG GP+G GPPG G +G PG GS+G G PG PG G RGP Sbjct: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGP 1367 Query: 1874 PGPPG 1878 PG PG Sbjct: 1368 PGEPG 1372 Score = 228 bits (580), Expect = 6e-59 Identities = 156/398 (39%), Positives = 183/398 (45%), Gaps = 101/398 (25%) Query: 1583 GPPGPPGPAGG----------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 1632 GP GPPG G PG +GP+GE+G G G PG +G G GPQGP GP G Sbjct: 843 GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 902 Query: 1633 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR--- 1689 G ++G G G AG PG PG G PG GPPG +G PG RG GKDG G + Sbjct: 903 KG-----QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957 Query: 1690 ------GPPGPPGSPGSPGVTGP--SGKPGKPGDHGRPGPSGLKGEKGDRGDI-ASQNMM 1740 GP GP G PG+PG+ GP GK G+PG G PG G G K G + S+N Sbjct: 958 GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC- 1016 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQP-----GPPGPPGPP---GSAGAR 1792 + GQ + ++ IP SR P GPPGP GPP GS G+R Sbjct: 1017 ----------ALGGQCVKGDRGAPGIPGS-PGSRGDPGIGVAGPPGPSGPPGDKGSPGSR 1065 Query: 1793 GEP------GPGGRPGFPGTPGMQGPP--------------------------------- 1813 G P GP GR G PG PG +GPP Sbjct: 1066 GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLP 1125 Query: 1814 ------GERGLPGEKGERGT----GSSGPRGLPGPP---GPQG-ESRTGPPGSTGSRGPP 1859 G++G+PG+ G GT G +GP GLPGPP GPQG + G G G +G Sbjct: 1126 GLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ 1185 Query: 1860 GPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG PG G G PGPPG D A+ P QG PG Sbjct: 1186 GHPGVPGFMGPPGNPGPPG-ADGIAGAAGPPGIQGSPG 1222 Score = 221 bits (564), Expect = 4e-57 Identities = 151/385 (39%), Positives = 171/385 (44%), Gaps = 112/385 (29%) Query: 1583 GPPGPPGPAGGPGAKGP------RGERGISG---AIGPPGPRGDIGPPGPQGPP--GPQG 1631 GP GPPG G PG +G RGE+G +G + GP GPRGD G PG GPP G G Sbjct: 928 GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 987 Query: 1632 PNGL----SIPGEQGR-----------------QGMKGDAGEPGLPGRTGTPGLP----- 1665 GL +PG G Q +KGD G PG+PG G+ G P Sbjct: 988 EPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVA 1047 Query: 1666 GPPGPMGPPGDRGFTGK---DGAMGPRGPPGPPGSPGSPGVTGPSGKPG-----KPGD-- 1715 GPPGP GPPGD+G G G GP+GP G G+PG+PG GP GKPG PGD Sbjct: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDIN 1107 Query: 1716 -----------HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLN 1764 G PG GL G KGD+G + G+ R Sbjct: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKG-------------------VPGKPGR------ 1142 Query: 1765 QIPNDYQSSRNQPGPPGPPGPPGSA---------GARGEPGPGGRPGFPGTPGMQGPPGE 1815 + + + GPPG PGPPG A GA GE G G G PG PG GPPG Sbjct: 1143 ---EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 1199 Query: 1816 RGLPGEKGERGT----------------GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGP 1858 G PG G G G GP GLPG PG +G E R G PG G G Sbjct: 1200 PGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK 1259 Query: 1859 PGPPGRPGNSGIRGPPGPPGYCDSS 1883 G PG PG G RGPPG G+ S Sbjct: 1260 AGEPGLPGPEGARGPPGFKGHTGDS 1284 Score = 214 bits (545), Expect = 6e-55 Identities = 155/428 (36%), Positives = 173/428 (40%), Gaps = 115/428 (26%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SI 1637 Q G GP GP G PGAKG G G GA G PG G +G PGP GPPG G GL Sbjct: 885 QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGT 944 Query: 1638 PGEQGRQGMKGDAGEPGLPGRTG------TPGLPGPPGPM--GPPGDRGFTGKDGAMGP- 1688 PG+ G +G KG AGE G PG G PGLPGPPG G PG RG G G +G Sbjct: 945 PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 1004 Query: 1689 ----------------------RGPPGPPGSPGSPG-----VTGPSGKPGKPGDHGRPGP 1721 RG PG PGSPGS G V GP G G PGD G PG Sbjct: 1005 AACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGS 1064 Query: 1722 SGLKGEKGDRG-----------------------DIASQNMMRAVARQVCEQLISGQMNR 1758 GL G G +G + S + +A+ VC G Sbjct: 1065 RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPG- 1123 Query: 1759 FNQMLNQIPN--------------DYQSSRNQPGPPGPPGPPGSAG---------ARGEP 1795 L +P + + + GPPG PGPPG AG A GE Sbjct: 1124 ----LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEV 1179 Query: 1796 GPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----------------GSSGPRGLPGPP 1839 G G G PG PG GPPG G PG G G G GP GLPG P Sbjct: 1180 GQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIP 1239 Query: 1840 GPQG----ESRTGPPGSTGSRGPPG------PPGRPGNSGIRGPPGPPGYCDSSQCASIP 1889 G +G + + GPPG G G PG G PG G G G PG S +P Sbjct: 1240 GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLP 1299 Query: 1890 YNGQGYPG 1897 +G PG Sbjct: 1300 -GQEGLPG 1306 Score = 211 bits (538), Expect = 4e-54 Identities = 148/415 (35%), Positives = 167/415 (40%), Gaps = 134/415 (32%) Query: 1559 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPP---------------GPAGGPGAKGPRGER 1603 +P G P P +G PG P GP G PG KG GER Sbjct: 721 VPGPPGPGGSPGLPGE-------IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER 773 Query: 1604 GISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-------SIPGEQGRQGMKGD------- 1649 G G G PG RG+IG G G PG +G GL + GE+G QG KG+ Sbjct: 774 GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833 Query: 1650 -----------AGEPGLPGRT-------------------GTPGLP------------GP 1667 AG PGLPG T G PGLP GP Sbjct: 834 GDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893 Query: 1668 PGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 1727 GP GPPG +G G GA G G PG PG G+PG +GP G G PG G PG G +GE Sbjct: 894 QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953 Query: 1728 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 1787 KG G+ S + R PG PG PGPPG Sbjct: 954 KGAAGEEGSPGPV-------------------------------GPRGDPGAPGLPGPPG 982 Query: 1788 SAGARGEPGPGGRPGFPG-----------------------TPGMQGPPGERGLPGEKGE 1824 G GEPG G PG PG G +G PG G PG +G+ Sbjct: 983 K-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGD 1041 Query: 1825 RGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G G +GP G GPPG +G G PG G +GP G G PGN G RGPPG PG Sbjct: 1042 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096 Score = 133 bits (334), Expect = 2e-30 Identities = 67/187 (35%), Positives = 112/187 (59%), Gaps = 3/187 (1%) Query: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 94 D+V L+D S S+G+ +F VR +++ +V+ F++GP R ++ + +YS P T ++L Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 95 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRAR---KIGVLITDGKSQDD 151 ++ + A L Y GGNT TG AL +I ++F AG RPR R ++ +L+TDG+SQD Sbjct: 98 QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157 Query: 152 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 211 V + G+ +FA+G+ A + EL+ IA++P H ++V+DF ++ +I L L Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217 Query: 212 CNSVKGP 218 C +V P Sbjct: 218 CENVLCP 224 Score = 108 bits (269), Expect = 6e-23 Identities = 59/128 (46%), Positives = 67/128 (52%), Gaps = 13/128 (10%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 PA+ S +Q GPPGPPG G PG GP GE G G G GP G IGP G +G G Sbjct: 1489 PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 1545 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 G G+ + GE G G+ G GEPG + G PG+PGP G GP G G Sbjct: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGPAGHPGLP-------- 1596 Query: 1689 RGPPGPPG 1696 GPPGPPG Sbjct: 1597 -GPPGPPG 1603 >gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] Length = 1284 Score = 427 bits (1098), Expect = e-119 Identities = 249/665 (37%), Positives = 369/665 (55%), Gaps = 22/665 (3%) Query: 28 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEW 87 CL AD+V LVDGSWSIG ++F+ V+ F++ ++ F+IGP +VQ+ L QYSGD +TEW Sbjct: 172 CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEW 231 Query: 88 QLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGK 147 LN+ K+ +L AV L YKGGNT TG+AL + QN + AG+RP A K+ +L+TDGK Sbjct: 232 DLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGK 291 Query: 148 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDL 207 SQDDV ++ LKD GV +FA+G+KNADE EL+++A+ P D ++V DF L + L Sbjct: 292 SQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLL 351 Query: 208 TINLCNSVKGPG------------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY 255 + +C ++G L AP++LV+S+ T S R+SWTP +Y + + Sbjct: 352 SRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVW 411 Query: 256 YPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVV- 314 GG +E V ST L +L TEY+V+V+ + E E L+G T P+P Sbjct: 412 RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471 Query: 315 SLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 374 +L + V P T+H+ WQP GAT Y++ P +EV++G ++ L L P Sbjct: 472 ALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRP--EVLLDGLEPG 529 Query: 375 TEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIV 434 +Y V+VQ++ SE +R T L P+ L DV+H VFWE P VR V Sbjct: 530 RDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589 Query: 435 RYKTPEEDVK-EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 493 Y + E + E + TS +L L S T YTV V+ ++ G S +T + TT+ P+ Sbjct: 590 TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPS 649 Query: 494 PTNLKITEVTSEGFRGTWDHGA-SDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNP 552 P+ L +TE+ + + W A S V +Y+ITW P G E + G+ T V L Sbjct: 650 PSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGR 709 Query: 553 NTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA 612 +T Y+V+I A Y D + SD + S R P +++P P NL + + T +SL V W P Sbjct: 710 HTEYDVTILAYYRDGARSDPV--SLRYTPSTVSRSP---PSNLALASETPDSLQVSWTPP 764 Query: 613 SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMT 672 GRV Y +TY P++G G E++ ++ G ++ V L L+ T Y + VS++Y G ++ Sbjct: 765 LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 Query: 673 GRGKT 677 G+T Sbjct: 825 ATGQT 829 Score = 355 bits (910), Expect = 3e-97 Identities = 189/491 (38%), Positives = 275/491 (56%), Gaps = 46/491 (9%) Query: 1336 VCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNA 1395 V T ++CP + DG + PGF ++ A++L EK +AS++GV++E +F + + K+A Sbjct: 823 VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881 Query: 1396 FVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTL 1455 + + +D++P LPP +TI+ L RLLPETP + FA+WQ+T D++P +GV+ D K+L Sbjct: 882 QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941 Query: 1456 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGN 1515 ++F++D R +Q TFD +EV+ +F+GSFHKVH+ V V++Y+DC ++ E+ + E G+ Sbjct: 942 TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001 Query: 1516 ITTDGYEILGKLLKGE---RKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFP 1572 G+ LG+L K SAAFQ+Q IVCS W DRCC++P+ RD CPAF Sbjct: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061 Query: 1573 NSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 1632 ++C+C+ ++ GPPGP G PPG G G PG QG PGP+GP Sbjct: 1062 SACSCSSETPGPPGPQG---------------------PPGLPGRNGTPGEQGFPGPRGP 1100 Query: 1633 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 1692 G+KG+ G+ GLPG G PG G PG +G G +G G +G G GPP Sbjct: 1101 -----------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 Query: 1693 GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLI 1752 GP G G G G SG+ G P G GP+GL G KG+RG+ + + + V + Sbjct: 1150 GPRGFQGMAGARGTSGERGPP---GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASH 1206 Query: 1753 SGQMNRFNQMLNQIPNDYQSSRNQPG--PPGPPGPPGSAGARGEPGPGGR----PGFPGT 1806 + + F++ + P + +PG P G PG A GE G GGR G PG Sbjct: 1207 VSKFDSFHEN-TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGA 1265 Query: 1807 PGMQGPPGERG 1817 G G PG++G Sbjct: 1266 VGQMGSPGQQG 1276 Score = 178 bits (452), Expect = 4e-44 Identities = 142/467 (30%), Positives = 211/467 (45%), Gaps = 22/467 (4%) Query: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 550 +PAPT+L +++VTS R +W Y I W E ++ G + NL Sbjct: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436 Query: 551 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 610 T Y VS+ IY G L L T AP PR L + T ++ + W Sbjct: 437 ASRTEYLVSVFPIYEG--------GVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ 488 Query: 611 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLY-PDGEGG 669 P++G Y + P++ +G E+ + + V+L L+P Y ++V SL P+G Sbjct: 489 PSAGATH-YLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEA 547 Query: 670 RMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPG 729 R R +T L R+L D S V W+ A R ++ Y + GG PG Sbjct: 548 RGI-RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG 606 Query: 730 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQV-YNPTP-NSLD 787 N A L L T+YTV V +Y GG ++ TGR + Q+ P +++ Sbjct: 607 NATSATLGPLSSSTTYTVRVTCLYP--GGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 Query: 788 VRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSD 846 + W AP VL Y++ ++P+ G + I VPGN L L T Y V ++A Y D Sbjct: 665 LAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRD 723 Query: 847 GEGNPSPAQGR----TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 902 G P R T+ RS P NL + ET +SL V+W G V Y + Y+P G Sbjct: 724 G-ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLG 782 Query: 903 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 949 ++ +VPG R++V L LQ T Y++ V A+Y G ++ G+T Sbjct: 783 PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Score = 145 bits (367), Expect = 3e-34 Identities = 102/326 (31%), Positives = 147/326 (45%), Gaps = 35/326 (10%) Query: 1054 DTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF--- 1109 D +KW + Y +++ P G QE+ + GLSP Y + +F Sbjct: 40 DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99 Query: 1110 -------------------------VQTPNLEGPGVSVKEHTTVKPTEAPTEPP---TPP 1141 Q P G HT E +EP TP Sbjct: 100 GSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPS 159 Query: 1142 PPPTIP--PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQV 1199 P P P AD+VFL D SWSIG +F +V F+ + + F EI P +QV Sbjct: 160 QDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKVQV 218 Query: 1200 SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK 1259 QYS + ++E+ LN+ + K L A++ +RY+GGNT TG ALT + + L +G+R Sbjct: 219 GLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP 278 Query: 1260 NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV 1319 KV+++VTDG+SQD+V AA V++ G +VF VGV + D EL +AS P + V V Sbjct: 279 EAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSV 338 Query: 1320 DDFESFEKIEDNLITFVCETATSSCP 1345 DF + L +C+ P Sbjct: 339 LDFLQLGALAGLLSRLICQRLQGGSP 364 Score = 143 bits (360), Expect = 2e-33 Identities = 124/454 (27%), Positives = 193/454 (42%), Gaps = 11/454 (2%) Query: 592 PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKP 651 P +L + TS+S+ + W PA KY I ++ S G G + + G S L L Sbjct: 380 PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRG-GTPREVVVEGPAASTELHNLAS 438 Query: 652 DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 711 T Y ++V +Y G G + G T PL R L + + T+++ W + G Y Sbjct: 439 RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG-ATHYL 497 Query: 712 LFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 770 + +PA+ G EE + +L L+P Y V+V + RT Sbjct: 498 VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557 Query: 771 GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 830 R++ + + ++ V W+ AP PV RV Y +G ++ PGN L L Sbjct: 558 APPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQT-EAPGNATSATLGPL 616 Query: 831 IPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAW-DHADGPVQ 889 T Y+V + LY G + + T P L + +++ +AW A V Sbjct: 617 SSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVL 676 Query: 890 QYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG---DGGHLTGN 946 Y+I ++P +G+ +VPG +L L T Y +T++A Y DG D L Sbjct: 677 VYQITWTP-LGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYT 735 Query: 947 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTS 1004 TV PP N+ ++ E +VSW P VL Y + Y P P + + G + Sbjct: 736 PSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSH 795 Query: 1005 YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 1038 TL +L +T Y V V A Y +G S ++ G T Sbjct: 796 VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Score = 113 bits (283), Expect = 2e-24 Identities = 94/332 (28%), Positives = 145/332 (43%), Gaps = 8/332 (2%) Query: 782 TPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLV 841 T +S+ + W PAP L+Y +V+ G P E +VV G L L T Y V++ Sbjct: 389 TSSSIRLSWTPAPRHPLKYLIVWRASRGGTPRE-VVVEGPAASTELHNLASRTEYLVSVF 447 Query: 842 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 901 +Y G G T P PR L + T ++ + W + G Y + SP Sbjct: 448 PIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATH-YLVRCSPASPK 506 Query: 902 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG-NGRTVGLLPPQNIHI 960 +E V R V+L L+P Y+++V ++ +G G RT L PP+++ Sbjct: 507 GEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGIRARTPTLAPPRHLGF 565 Query: 961 SDEWYTRFRVSWDPSPSPVLGYKIVY-KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 1019 SD + RV W+ +P PV ++ Y G + G TS TL L+ STTY V Sbjct: 566 SDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVR 625 Query: 1020 VYAQYDSGLSVPLTDQGTTLYL-NVTDLKTYQIGWDTFCVKW--SPHRAATSYRLKLSPA 1076 V Y G S LT + TT + + L ++ D + W + Y++ +P Sbjct: 626 VTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL 685 Query: 1077 DGTRGQEITVRGSETSHCFTGLSPDTDYGVTV 1108 + EI+V G+ + GL T+Y VT+ Sbjct: 686 GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTI 717 Score = 106 bits (264), Expect = 2e-22 Identities = 59/125 (47%), Positives = 69/125 (55%), Gaps = 20/125 (16%) Query: 1773 SRNQPGPPGPPGPPG------SAGARGEPGPGGRPGFPGT------PGMQGPPGERGLPG 1820 S PGPPGP GPPG + G +G PGP G PG G PG+QG PG +G+PG Sbjct: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 Query: 1821 EKGERGT----GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPP---GPPGRPGNSGIRG 1872 G +G G G GLPGPPGP+G + G G++G RGPP GP G PG G RG Sbjct: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 Query: 1873 PPGPP 1877 G P Sbjct: 1187 EKGEP 1191 Score = 106 bits (264), Expect = 2e-22 Identities = 85/241 (35%), Positives = 89/241 (36%), Gaps = 63/241 (26%) Query: 1665 PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 1724 PGPPGP GPPG G G G G GP GPPG G G G G G PG G PG GL Sbjct: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 Query: 1725 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 1784 +G KG RG G PGPPG Sbjct: 1131 QGPKGMRG----------------------------------------LEGTAGLPGPPG 1150 Query: 1785 P---PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT------------GS 1829 P G AGARG G G PG G G+ GP GERG GE T Sbjct: 1151 PRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210 Query: 1830 SGPRGLPGPPGPQGESR----TGPPGSTGSRGPPGPPGRPGNSGI----RGPPGPPGYCD 1881 PP P E + T P GS G+R PG G G RG PG G Sbjct: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270 Query: 1882 S 1882 S Sbjct: 1271 S 1271 Score = 53.5 bits (127), Expect = 2e-06 Identities = 73/296 (24%), Positives = 109/296 (36%), Gaps = 17/296 (5%) Query: 852 SPAQGR-------TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 904 SP QG TLP P +L + T++S+ ++W A +Y I++ + G Sbjct: 363 SPRQGPAAAPALDTLP--APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420 Query: 905 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 964 E V G + L L T Y ++V +YE G G L G T L PP+ + ++ Sbjct: 421 E-VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479 Query: 965 YTRFRVSWDPSPSPV--LGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYA 1022 ++W PS L P G E E VG L L P Y+V+V + Sbjct: 480 PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGR-PEVLLDGLEPGRDYEVSVQS 538 Query: 1023 -QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTR 1080 + G T L + D V W R R+ ++G Sbjct: 539 LRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGH 598 Query: 1081 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTE 1136 + G+ TS LS T Y V V P G ++ T K +P++ Sbjct: 599 SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG--GGSSTLTGRVTTKKAPSPSQ 652 Score = 47.4 bits (111), Expect = 1e-04 Identities = 28/62 (45%), Positives = 30/62 (48%), Gaps = 12/62 (19%) Query: 1836 PGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGY 1895 PGPPGPQG PPG PG G PG G GP GPPG +P QG+ Sbjct: 1071 PGPPGPQG-----PPGL------PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP-GLQGH 1118 Query: 1896 PG 1897 PG Sbjct: 1119 PG 1120 Score = 32.7 bits (73), Expect = 3.5 Identities = 29/127 (22%), Positives = 49/127 (38%), Gaps = 16/127 (12%) Query: 696 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 755 L ++W +EG+ Y + P AG E+ V + T A + L P YT+ + + Sbjct: 42 LQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGS 101 Query: 756 G-----------DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVY 804 G + ++S R+ R L PTP+ P P + +V + Sbjct: 102 GRFLLARREFVIEDLKSSSLDRSSQRPLGSGAP--EPTPSHTG---SPDPEQASEPQVAF 156 Query: 805 SPVDGTR 811 +P R Sbjct: 157 TPSQDPR 163 >gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] Length = 957 Score = 382 bits (981), Expect = e-105 Identities = 291/935 (31%), Positives = 389/935 (41%), Gaps = 214/935 (22%) Query: 1150 RDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVK 1209 R C+ A D+VF+ D S+S+G +NF V K++ N FD I P IQV VQYSD Sbjct: 28 RSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFD-IGPKFIQVGVVQYSDYPV 86 Query: 1210 SEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVT 1269 E L +Y+ A+++I Y GGNT+TGKA+ F + + S + + K+ VV+T Sbjct: 87 LEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSS---RFLTKIAVVLT 143 Query: 1270 DGRSQDEVKKAALVIQQSGFSVFVVGV-ADVDYNELANIASKPSERHVFIVDDFESFEKI 1328 DG+SQD+VK AA + S ++F +GV ++ + EL IA+KPS +VF V+D+ + KI Sbjct: 144 DGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKI 203 Query: 1329 EDNLITFVCETATSSCPL-IYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYS 1387 + + +CE S CP I + GF +L ++ +K +Q S Sbjct: 204 REVMKQKLCEE--SVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQL------SPKKIK 255 Query: 1388 AYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVI 1447 Y + +++ T+++ P GLPPSY + R + D +W+I D +PQ+ V Sbjct: 256 GYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWD---LWRILTIDGRPQIAVT 312 Query: 1448 ADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIE 1507 + K L F Q VTF +VKTLF +H++ ++VT + V +YID +I Sbjct: 313 LNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIEN 372 Query: 1508 KDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDE-- 1565 K + I +G +GK G+ ++ F +Q I C P +R+ C+IP E Sbjct: 373 KPLHPVLGILINGQTQIGKY-SGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECL 431 Query: 1566 ---GKCPAFPNSCTCTQDSVGPPGP----------------------------------- 1587 + P C C G GP Sbjct: 432 NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG 491 Query: 1588 ----------PGPAGGPGAKGPRGERGISG---AIGPPGPRGDIGPPGPQGPPGPQGPNG 1634 PG G PG G +G+RG+ G G PG +G++G G +G PG G G Sbjct: 492 SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551 Query: 1635 LS----------IPG---EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 1681 +PG E GR G G G PG G G+PG PG G G PG GF G Sbjct: 552 AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611 Query: 1682 KDGAMGPRGPPGPP------------------GSPGSPGVTGPSGKPGKPGDHGRPGPSG 1723 G MG +G GPP GSPG PG G G G+PG G PG SG Sbjct: 612 NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671 Query: 1724 LKGEKGDRGDIASQNMMRAVARQ--------VCEQLISGQMNRFNQMLNQIPNDY----- 1770 LKGE G G M Q E+ I GQ + IP Sbjct: 672 LKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR--QGIPGQQGIQGH 729 Query: 1771 ------QSSRNQP------------------GPPGPPGPPGSAGARGEPGPGGRP----- 1801 + + +P GP GP G PG G +G PG G+P Sbjct: 730 HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFS 789 Query: 1802 --------------------------------------GFPGTPGMQGPPGERGLPGEKG 1823 G PG PG GP G RGLPG G Sbjct: 790 EQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPG 849 Query: 1824 ERGT-------GSSGPRGLPGPPGPQGE---------SRTGPPGSTGSRGPP-----GPP 1862 G G G RGL G PG GE GPPG G GPP GPP Sbjct: 850 RDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPP 909 Query: 1863 GRP---------GNSGIRGPPGPPGYCDSSQCASI 1888 G P G GI+G PGPPG CD S C S+ Sbjct: 910 GDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSV 944 Score = 198 bits (504), Expect = 4e-50 Identities = 129/352 (36%), Positives = 156/352 (44%), Gaps = 46/352 (13%) Query: 1583 GPPGPPGPAGGPGAKGPRGE---RGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIP 1638 G G G AG PG GP GE G G +G PG +G+ G PG G G +G G+ P Sbjct: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610 Query: 1639 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP 1698 G +G G KG+ G PG G+ G PG+PG G G PG G G G+ G G G PG+ Sbjct: 611 GNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGAS 670 Query: 1699 GSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC--EQLISGQM 1756 G G G +G PG+PG G PG G KG+KG++G+ Q RQ +Q I G Sbjct: 671 GLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHH 730 Query: 1757 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 1816 + + + +PG G G G +G G GP G G PG PG QGPPG Sbjct: 731 GAKGE---------RGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLD 781 Query: 1817 GLPGEKG-----------------------------ERGTGSSGPRGLPGPPGPQG-ESR 1846 G PG + + G G+PGPPGP G E Sbjct: 782 GKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841 Query: 1847 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG-QGYPG 1897 G PG G G PG G PG G+RG G PG Y G QG PG Sbjct: 842 RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPG 893 Score = 130 bits (328), Expect = 9e-30 Identities = 80/229 (34%), Positives = 126/229 (55%), Gaps = 15/229 (6%) Query: 16 LLLSSIEAEGME----CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKR 71 LL +S+ AE E C T A D+V ++DGS+S+G NF V+ ++ I + FDIGPK Sbjct: 15 LLQNSVLAEDGEVRSSCRT-APTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKF 73 Query: 72 VQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAG 131 +Q+ + QYS P E L ++ + L AV ++ Y GGNT TG A+ F F + Sbjct: 74 IQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSR 133 Query: 132 MRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGI-KNADEVELKMIATDPDDTH 190 KI V++TDGKSQDDV+ ++ +D + LFAIG+ ++ EL+ IA P T+ Sbjct: 134 F---LTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTY 190 Query: 191 AYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRV 239 + V D+ ++S+I + + LC + P+ + ++ R R F + Sbjct: 191 VFYVEDYIAISKIREVMKQKLCE------ESVCPTRIPVAARDERGFDI 233 Score = 43.5 bits (101), Expect = 0.002 Identities = 29/80 (36%), Positives = 33/80 (41%), Gaps = 8/80 (10%) Query: 1818 LPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 1877 +PG GE G S P P G PG G +G PG PG PG G G G P Sbjct: 423 IPGFNGECLNGPSDVGSTPAPC----ICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKP 478 Query: 1878 GYCDSSQCASIPYNGQGYPG 1897 GY + +P G PG Sbjct: 479 GYQGIAGTPGVP----GSPG 494 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 353 bits (906), Expect = 9e-97 Identities = 310/1044 (29%), Positives = 480/1044 (45%), Gaps = 62/1044 (5%) Query: 9 LAALGAALLLSSIEA-----EGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVE 63 +AAL A +L + E + C ADIV L+DGS SIGR+NFR VRSF+ +V Sbjct: 7 VAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVL 66 Query: 64 VFD--IGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFI 121 F + V+ A QYS DPRTE+ L+A +++A+ L YKGGNT TG A+ + Sbjct: 67 PFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHV 126 Query: 122 RQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKM 181 F Q RP K+ +LITDGKSQD V+ +++LK +GV+LFA+GIKNAD ELK Sbjct: 127 ADHVFLPQLA-RPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKR 185 Query: 182 IATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKG------PGD-LEAPSNLVISERTH 234 +A+ P + V DF L ++ ++ +C + G P D AP +LV+SE + Sbjct: 186 VASQPTSDFFFFVNDFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSS 245 Query: 235 RSFRVSWTPPSDSVDRYKVEYYPVSG------GKRQEFYVSRMETSTVLKDLKPETEYVV 288 +S RV WT S V YKV+Y P++G +RQE V ETS L+ L+P TEY V Sbjct: 246 QSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQV 305 Query: 289 NVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKD 348 V ++ + E + GT +T + L I + ++ V W+ V GATGY ++++ V Sbjct: 306 TVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGATGYRVTWR-VLS 364 Query: 349 TEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDL 408 PT+ +E LGP + L DL P T+Y VTV + L + P T Q L Sbjct: 365 GGPTQQQE--LGPGQGSVLLRDLEPGTDYEVTV-STLFGRSVGPATSLMARTDASVEQTL 421 Query: 409 KLRDVTHSTMNVFWEPVPGKVRKYIV--RYKTPEEDVKEVEVDRSETSTSLKDLFSQTLY 466 + + +++ + W VP + R Y + R +T E ++V + T L L T Y Sbjct: 422 RPVILGPTSILLSWNLVP-EARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEY 480 Query: 467 TVSVSAV---HDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRI 523 +++ + H+ V PV T+L+ TE+ + R +W + YRI Sbjct: 481 RLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWS-PVPGATQYRI 539 Query: 524 TWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITA-IYPDESESDDLIGSERTLPI 582 ++ +L G + +++ Y V ++A + P E GS L + Sbjct: 540 IVRSTQGVER-TLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPRE-------GSASVLTV 591 Query: 583 LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQN 642 L+V + + + V W P G +RI++ STG G E + T+ Sbjct: 592 RREPETPLAVPGLRVVVSDATRVRVAWGPVPG-ASGFRISW--STGSGPESSQTLPPDST 648 Query: 643 SVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDH 702 + + L+P T Y + VS L EG +T PL VR + V S+S++ + W Sbjct: 649 ATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTR 708 Query: 703 AEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTS 762 G Y++ + +A GPE+ + G A L L+PDT YTV V DG S Sbjct: 709 VPG-ATGYRVSW-HSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPAS 766 Query: 763 DTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPG 820 RT + R +Q+ N + + L + W G YR+ + +G P ++PG Sbjct: 767 VVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG-ATAYRLAWGRSEG-GPMRHQILPG 824 Query: 821 NTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPR--NLRVFGETTNSLS 878 NT + L YSV + AL D EG P T P + P L V +SL Sbjct: 825 NTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLR 884 Query: 879 VAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG 938 + W+ Q + + + P G ++ + ++ L L+P T Y++ + + G Sbjct: 885 LRWEPVP-RAQGFLLHWQPEGGQ--EQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAG 941 Query: 939 DGGHLTGNGRTVG-LLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPV---GSNEP 994 +G RT +P + + D ++W P S Y + ++P+ G P Sbjct: 942 EGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTP-VSRASSYILSWRPLRGPGQEVP 1000 Query: 995 --MEAFVGEMTSYTLHNLNPSTTY 1016 + G +S + L P +Y Sbjct: 1001 GSPQTLPGISSSQRVTGLEPGVSY 1024 Score = 263 bits (672), Expect = 1e-69 Identities = 262/1054 (24%), Positives = 441/1054 (41%), Gaps = 91/1054 (8%) Query: 325 TMHVQWQPVGG-ATGYILSYKPVKDTE---PTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 380 ++ VQW G TGY + Y P+ P+ +EV + ++L L P TEY VT Sbjct: 247 SLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVT 306 Query: 381 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 440 V A+ + E V+ T L P+ L +++ T ++ V W VPG + Sbjct: 307 VIALYANSIGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPGATGYRVTWRVLSG 365 Query: 441 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVT--------AQETTRPVP 492 ++ E+ + S L+DL T Y V+VS + P + ++T RPV Sbjct: 366 GPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRPVI 425 Query: 493 -APTNLKITEVTSEGFRGTWDHGASDVSLYRITWA-PFGSSDKMETILNGDENTLVFENL 550 PT++ ++ RG YR+ W G + +L D + L Sbjct: 426 LGPTSILLSWNLVPEARG-----------YRLEWRRETGLEPPQKVVLPSDVTRYQLDGL 474 Query: 551 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 610 P T Y +++ + + + T+ + P S +LQ + V W Sbjct: 475 QPGTEYRLTLYTLLEGHE-----VATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWS 529 Query: 611 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGR 670 P G Q YRI + + +G E+T + G Q + L ++ YT+ VS+ EG Sbjct: 530 PVPGATQ-YRIIVRST--QGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586 Query: 671 --MTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP 728 +T R + + V LRV + + V W G +++ ++ +G PE +P Sbjct: 587 SVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPG-ASGFRISWSTGSG-PESSQTLP 644 Query: 729 GNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDV 788 ++ + LQP T+Y V V + +G RT G R V V + +S+ + Sbjct: 645 PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTI 704 Query: 789 RWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGE 848 W PG YRV + G P +S +V G + L+ L PDT Y+V++ A + + Sbjct: 705 TWTRVPGAT-GYRVSWHSAHG--PEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVD 761 Query: 849 GNPSPAQGRTLPRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEY 906 G P+ RT P R L++ +++ L + W G YR+ + + G P+ + Sbjct: 762 GPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATA-YRLAWGRSEGGPM-RH 819 Query: 907 TTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQ--NIHISDEW 964 +PG ++ ++ L+ Y + V A+ D +G ++ T PP +H+ Sbjct: 820 QILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRG 879 Query: 965 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDV--NVYA 1022 R+ W+P P G+ + ++P G E E++SY L L P+T Y V +V Sbjct: 880 EHSLRLRWEPVPR-AQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLG 938 Query: 1023 QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ 1082 G S +T + + + +L+ D+ + W+P A+SY L P G GQ Sbjct: 939 PAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGP-GQ 997 Query: 1083 EI-----TVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 1137 E+ T+ G +S TGL P Y +F TP L+G P Sbjct: 998 EVPGSPQTLPGISSSQRVTGLEPGVSY---IFSLTPVLDG-------------VRGPEAS 1041 Query: 1138 PTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVV---KFIFNTVGGFDEISP 1194 T P VC AD+VFL A+ DN ++ + + V + P Sbjct: 1042 VTQTP---------VCPRGLADVVFLPHAT----QDNAHRAEATRRVLERLVLALGPLGP 1088 Query: 1195 AGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYR--GGNTRTGKALTFIKEKVLT 1252 +QV + YS F LN +D + L ++++ Y GN +T + + Sbjct: 1089 QAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAP 1148 Query: 1253 WESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIA-SKP 1311 G R++VP V+V++ D + ++ Q SG +V ++G+A D +L +A Sbjct: 1149 DAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMD 1208 Query: 1312 SERHVFIVDDFESFEKIEDNLITFVCETATSSCP 1345 S + F VDD S ++ L T +C+ + ++ P Sbjct: 1209 SVQTFFAVDDGPSLDQAVSGLATALCQASFTTQP 1242 Score = 234 bits (597), Expect = 6e-61 Identities = 145/331 (43%), Positives = 162/331 (48%), Gaps = 66/331 (19%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGP---------------PGPRGDIGPPGPQGPP 1627 G PG PGP G PG +GPRG +G GA G PGP G GP GP G P Sbjct: 1326 GSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDP 1385 Query: 1628 GPQGPNGLSIPGEQGRQGMKGDAGEPG------LPGRTGTPGLPGPP---GPMGPPGDRG 1678 GP+GP GL +G +G +G+ G PG PG G PGLPG P GP+GPPG +G Sbjct: 1386 GPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445 Query: 1679 FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIAS 1736 G D G G PG PGSPG G GP G G GD G PGP G GEKG+RG A Sbjct: 1446 EKG-DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAG 1504 Query: 1737 QNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG 1796 + VA +PG GP GPPG G +GE G Sbjct: 1505 SRGLPGVA------------------------------GRPGAKGPEGPPGPTGRQGEKG 1534 Query: 1797 PGGRPGFPGT--PGMQGPPGERGLPGEKGERG-TGSSGPRG-----LPGPPGPQGE-SRT 1847 GRPG P P + GP GE+G G G RG TG G RG LPG PGP+G+ Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR 1594 Query: 1848 GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GP G TG GPPG G PG G G PGPPG Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625 Score = 233 bits (594), Expect = 1e-60 Identities = 158/388 (40%), Positives = 185/388 (47%), Gaps = 95/388 (24%) Query: 1583 GPPGPPGPAGGPGAKGP--------RGERGISGAIGPPGPR------GDIGPPGPQGPPG 1628 GPPGP GP G PG +GP +G++G G GPPGP G+ G PG G PG Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP---PGPMGPPGDRGFTG---K 1682 PQGP G PG++G +G D G PGLPG+ G+PG GP PG +GP GDRGF G + Sbjct: 1434 PQGPVGP--PGKKGEKGDSED-GAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGE 1490 Query: 1683 DGAMGPRGPPGPPGSPGSPGVT------------GPSGKPGKPGDHGRPGP--------S 1722 G G RGPPGP GS G PGV GP+G+ G+ G+ GRPG + Sbjct: 1491 AGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVA 1550 Query: 1723 GLKGEKGDRGDIASQNMMRAVARQVCEQLI----------------SGQMNRFNQMLNQI 1766 G KGEKGD G + + L+ G R + Sbjct: 1551 GPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG 1610 Query: 1767 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP------GMQGPPGERGLPG 1820 P + +PGPPGP GP G G GE G G PG PG P G++G PG RG G Sbjct: 1611 PPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVG 1670 Query: 1821 EKGERG----------TGSSGP---RGLPGPPGPQGE--------SRTGPPGSTGSRGPP 1859 EKG++G GSSGP RG PGPPGP G G PG G GP Sbjct: 1671 EKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPR 1730 Query: 1860 GP------PGRPGNSGI---RGPPGPPG 1878 GP PG PG GI RGPPGP G Sbjct: 1731 GPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Score = 231 bits (589), Expect = 5e-60 Identities = 151/347 (43%), Positives = 167/347 (48%), Gaps = 51/347 (14%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQ 1641 G PGP G G PG G RG G G G GPRG GP G G PGP G GL+ P G Q Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200 Query: 1642 GRQGMKGDAGEPGLPGR-----TGTPGLPGPPGP---MGP------PGDRGFTGKDGAMG 1687 G G+KG+ GE G PGR TG GLPGPPGP +GP PG G TGK GA G Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260 Query: 1688 ---------PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP--GPSGLKGEKGDRGDIAS 1736 RG PG PGSPG PG GP G+PG G G+ G G KGEKG G +A Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAG 2320 Query: 1737 QNMMRAVAR-------------QVCEQLISGQMNRFNQMLNQIPNDYQSSR--NQPGPPG 1781 + A+ + G Q P ++ PG PG Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPG 2380 Query: 1782 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 1840 PPGPPG G G PG G PG G PG GP GE G PG GERG G G G+PGP G Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440 Query: 1841 PQG-ESRTGPPGSTGSRGP--------PGPPGRPGNSGIRGPPGPPG 1878 P G GPPG++G +G PGP G G GIRG G PG Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG 2487 Score = 227 bits (578), Expect = 1e-58 Identities = 154/386 (39%), Positives = 176/386 (45%), Gaps = 86/386 (22%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGG------PGAKGPRGERGISGAIGPPGPRGDIGPPG 1622 P P+ G PG PG AGG PG +G RGE+G G G GP G G PG Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085 Query: 1623 PQGPPGP--------------QGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGL 1664 P GPPGP QGP GL PG G QG KGD G PG+ G G PG Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145 Query: 1665 PGPPGPMGPPGDRGFTG---KDGAMGPRGPPGP------PGSPGSPGVT------GPSGK 1709 G G G PG+RG G K G GPRGPPGP PG PG+PG+ GPSG Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205 Query: 1710 PGKPGDHGRPGPS--------GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 1761 G+PG+ G PG GL G G G + Q + QV E G R Sbjct: 2206 KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG-SPGLPGQVGETGKPGAPGRDG- 2263 Query: 1762 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP-----GFPGTPGMQGPP--- 1813 + R PG PG PG PG G +GEPGP G P G PG G +G P Sbjct: 2264 -----ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL 2318 Query: 1814 -----------GERGLPGEKGERG----------TGSSGPRGLPGPPGPQGESRTGPPGS 1852 G+RGLPG +GE+G G G +G PGP G +G+ G PGS Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS 2378 Query: 1853 TGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GPPGPPG G+ G+ G PG PG Sbjct: 2379 P---GPPGPPGVKGDLGLPGLPGAPG 2401 Score = 225 bits (574), Expect = 3e-58 Identities = 149/372 (40%), Positives = 172/372 (46%), Gaps = 82/372 (22%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---------------QGPP 1627 G PG GP G PGA GP+G+RG G +G G +G+ GPPGP +GP Sbjct: 1462 GSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521 Query: 1628 GPQGPNG-LSIPGEQGR--------------QGMKGDAGEPGLPGRTGTPG--------L 1664 GP GP G GE GR +G KGD G G G TG G L Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL 1581 Query: 1665 PGPPGPMGPPGDR---GFTGKDGAMGPRGPPGPPGSPGSPGVTGP------SGKPGKPGD 1715 PG PGP G PGDR G TG+ G G GPPG G PG PG GP G+ G+ GD Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD 1641 Query: 1716 HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 1775 G PG GL G+ G+RG + +R + +Q G+ R + P + R Sbjct: 1642 EGPPGDPGLPGKAGERG-LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGP---KGDRG 1697 Query: 1776 QPGPPGPP-------------GPPGSAGARGEPGPGGRPGFPGT------------PGMQ 1810 +PGPPGPP G PG G G GP G PG PG PG Q Sbjct: 1698 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ 1757 Query: 1811 GPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRP---G 1866 G PG RG GEKG+RG G G GL G PG G S GP G+ G G PG G P G Sbjct: 1758 GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS--GPNGAAGKAGDPGRDGLPGLRG 1815 Query: 1867 NSGIRGPPGPPG 1878 G+ GP GPPG Sbjct: 1816 EQGLPGPSGPPG 1827 Score = 224 bits (572), Expect = 5e-58 Identities = 140/341 (41%), Positives = 157/341 (46%), Gaps = 61/341 (17%) Query: 1583 GPPGPPGPAGGPGA---KGPRGERG-------ISGAIGPPGPRGDIGPPGPQGPPG-PQG 1631 GPPG GP G PG KG RG+ G G GPPGP G G PG G PG P Sbjct: 1988 GPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGR 2047 Query: 1632 PNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDR--------GFTGKD 1683 G+ G G +G +G+ GE G GR G PGLPG PGP GPPG + G +G+ Sbjct: 2048 AGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQ 2107 Query: 1684 GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 G G +G G PGS G G G G PG GD G PGP G G G G+ R + Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGE-------RGM 2160 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 1803 A +PG GP GPPG G G+PGP G PG Sbjct: 2161 A---------------------------GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193 Query: 1804 PGTPGMQGPPGERGLPGEKGERGTGSSGPR---GLPGPPGPQG----ESRTGPPGSTGSR 1856 G G QGP G +G PGE G G G +GP GLPGPPGP G + G PG G Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGET 2253 Query: 1857 GPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG PGR G SG G G PG S P +G PG Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPG-PVGPKGEPG 2293 Score = 223 bits (569), Expect = 1e-57 Identities = 153/391 (39%), Positives = 177/391 (45%), Gaps = 81/391 (20%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRGDIGPPGPQGPPGPQG---PNG 1634 GP GPPGP G G KG G G +GP G +GD+GP GP+G G QG P G Sbjct: 1519 GPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPG 1578 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPG---------PMGPPGDRGFTGKDGA 1685 L +PG+ G +G GD G GL GR G PG GPPG P GP G RG G+ G Sbjct: 1579 LVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE 1638 Query: 1686 MGPRGPPGPPGSP---------GSPGVTGP---SGKPGKPGDHGRPGPSGLKGEKGDRGD 1733 G GPPG PG P G+PGV GP G G PG+ GR G G G KGDRG+ Sbjct: 1639 KGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE 1698 Query: 1734 IASQNMMRAV------ARQVCEQLISGQMN----RFNQMLNQIPND--YQSSRNQPGPPG 1781 + AR+ E GQ + + L P + + R PGP G Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Query: 1782 PP---GPPGSAGARGEPGPGGRPGFPGTPGMQGP------------PGERGLPGEKGERG 1826 P GP G G RG PG GR G G PG GP PG GLPG +GE+G Sbjct: 1759 DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQG 1818 Query: 1827 -TGSSGPRGLPGPPGPQG-------------------ESRTGPPGSTGSRGPPGPPGRPG 1866 G SGP GLPG PG G + G G++G G GP G G Sbjct: 1819 LPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERG 1878 Query: 1867 NSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GI GP GPPG + GQG+PG Sbjct: 1879 APGILGPQGPPGL-----PGPVGPPGQGFPG 1904 Score = 222 bits (565), Expect = 3e-57 Identities = 134/350 (38%), Positives = 164/350 (46%), Gaps = 56/350 (16%) Query: 1580 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 D VG PG G G PG +G +GE G +G G PG G G PGP+G G G PG Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPG 2380 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM------GPPGDRGFT---GKDGAMGPRG 1690 G G+KGD G PGLPG G G PG GP GP G+RG G++G GP G Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440 Query: 1691 PPGPPGS--------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGL 1724 PPGPPGS G PG+ G G+PG+ G G GP G Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGS 2500 Query: 1725 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 1784 +GE+G++GD+ S + G M + P + GP G G Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDK---GPRGDNG 2557 Query: 1785 PPGSAGARGEP---------------GPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TG 1828 PG G++GEP GP G+PG G PG G PG+ G+PG +GE+G G Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617 Query: 1829 SSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GPRGL G G +G G G G +G GPPGRPG +G +G G PG Sbjct: 2618 FMGPRGLKGERGVKG--ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPG 2665 Score = 221 bits (562), Expect = 7e-57 Identities = 141/354 (39%), Positives = 173/354 (48%), Gaps = 71/354 (20%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP---PGPQGPNGLS-I 1637 +GPPGPPG G PGA G +G++G G +G PGPRG+ G PG +G PG +GP GL+ Sbjct: 2439 LGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP 2497 Query: 1638 PGEQGRQGMKGDAGEPGLPGRTGTPG-LPGPPGPMGPPGD---RGFTGKDGAMGPRGPPG 1693 PG +G +G KGD G GL G G + GPPGP G GD RG G DG GPRG G Sbjct: 2498 PGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNG 2557 Query: 1694 PPGS---------------PGSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIA 1735 PG PG G+ GP G+PG PGD G PG G+ G +G++GD+ Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617 Query: 1736 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 1795 E+ + G + + + + GPPG PG G G GEP Sbjct: 2618 FMGPRGLKG----ERGVKGACGLDGE---------KGDKGEAGPPGRPGLAGHKGEMGEP 2664 Query: 1796 GPGGRPGFPGTPGMQGPPGERGLPG---------EKGERGT-------------GSSGPR 1833 G G+ G PG G+ GP G+RG G EKGERGT GS+GP Sbjct: 2665 GVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPP 2724 Query: 1834 GLPGPPGPQG-------ESRTGPPGS--TGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G PG GP+G + GPPG G+ G PG PG G G GP GP G Sbjct: 2725 GPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778 Score = 218 bits (555), Expect = 4e-56 Identities = 139/317 (43%), Positives = 153/317 (48%), Gaps = 52/317 (16%) Query: 1584 PPGPPGPAGGP-GAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 1641 P P P P G KG GE G+ G +GPPG D G PG G PGPQGP G + GE+ Sbjct: 1242 PRPEPCPVYCPKGQKGEPGEMGLRGQVGPPG---DPGLPGRTGAPGPQGPPGSATAKGER 1298 Query: 1642 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGS---- 1697 G G G G PG G GTPG PG G G PG RG G+ G GP+G PG PG Sbjct: 1299 GFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGG 1358 Query: 1698 -----PGSPGVTGPSGKPGKPGDHGRPGPSG--------LKGEKGDRGDIASQNMMRAVA 1744 PG G GPSG PG G G PGP G +KG+KGDRG+ Sbjct: 1359 EGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPG---- 1414 Query: 1745 RQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARG--EPGPGGRPG 1802 G + L +P PGP GP GPPG G +G E G G PG Sbjct: 1415 --------EGGIAPGEPGLPGLP-------GSPGPQGPVGPPGKKGEKGDSEDGAPGLPG 1459 Query: 1803 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGP 1861 PG+PG QGP G G G KG+ RG PGP G GE GPPG GSRG PG Sbjct: 1460 QPGSPGEQGPRGPPGAIGPKGD--------RGFPGPLGEAGEKGERGPPGPAGSRGLPGV 1511 Query: 1862 PGRPGNSGIRGPPGPPG 1878 GRPG G GPPGP G Sbjct: 1512 AGRPGAKGPEGPPGPTG 1528 Score = 218 bits (555), Expect = 4e-56 Identities = 136/362 (37%), Positives = 168/362 (46%), Gaps = 74/362 (20%) Query: 1571 FPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ 1630 FP T + +G PGP +G G GP G GI G +GPPGP G +GPPG G G + Sbjct: 2405 FPGQ-TGPRGEMGQPGP---SGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460 Query: 1631 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP-------------------- 1670 G G+ +PG +G +G G GE G PG+ G GL GPPG Sbjct: 2461 GDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520 Query: 1671 -----MGPP---------GDRGFTGKDGAMGPRGPPGPPGS---------------PGSP 1701 +GPP G+RG G DG GPRG G PG PG Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580 Query: 1702 GVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNR 1758 G+ GP G+PG PGD G PG G+ G +G++GD+ E+ + G Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG----ERGVKGACGL 2636 Query: 1759 FNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGL 1818 + + + + GPPG PG G G GEPG G+ G PG G+ GP G+RG Sbjct: 2637 DGE---------KGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGF 2687 Query: 1819 PGEKGERG-TGSSGPRGLPGP---PGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP 1873 G+ G +G G G RG PG PGP G + GPPG GS GP GP G G G RGP Sbjct: 2688 DGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGP 2747 Query: 1874 PG 1875 PG Sbjct: 2748 PG 2749 Score = 217 bits (553), Expect = 8e-56 Identities = 153/423 (36%), Positives = 180/423 (42%), Gaps = 127/423 (30%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP------QGPPG-------- 1628 G GP GP G PG G GERGI G GPPGP+GD G GP +GPPG Sbjct: 1725 GQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784 Query: 1629 -------PQGPNGLS----------IPGEQGRQGMKGDAGEPGLPGR------------T 1659 P GPNG + +PG +G QG+ G +G PGLPG+ Sbjct: 1785 GKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKN 1844 Query: 1660 GTPGLPGPPGPMGPPGDRGFTGKDGAMGPR---------GPPGPPGSPGS--------PG 1702 G PG PG G G GD G +G++G GP+ GP GPPG PG PG Sbjct: 1845 GEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPG 1904 Query: 1703 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGD----------IASQNMMRAVARQVCE--Q 1750 V G +G G G+ G G GL GE+G RG+ + + + + R++ E Sbjct: 1905 VPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWD 1964 Query: 1751 LISGQMNRFNQMLNQIPND--------------------YQSSRNQPGPPGPP------- 1783 SG + D + R PGP GPP Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGER 2024 Query: 1784 GPPGSAGARGEPGPGGRPGFPGTP---GMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP 1839 GPPG +G GEPG G PG PG G G PGERG GEKGERG G GP GLPG P Sbjct: 2025 GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTP 2084 Query: 1840 GPQG------------------------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPG 1875 GP G + G PGS G +GP G G PG G RG PG Sbjct: 2085 GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPG 2144 Query: 1876 PPG 1878 P G Sbjct: 2145 PRG 2147 Score = 217 bits (552), Expect = 1e-55 Identities = 148/378 (39%), Positives = 169/378 (44%), Gaps = 100/378 (26%) Query: 1583 GPPGPPGPAG-----GPGAKGPRGERGISGAIGPPGPRGDIGPPGP---------QGPPG 1628 G PGPPGP G GPGA+ +GE G G GP GP+GD G PG +GPPG Sbjct: 1697 GEPGPPGPPGRLVDTGPGAR-EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG 1755 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGK 1682 PQG PG +G G KGD G PGL GR+G G PG GP GP GD G G Sbjct: 1756 PQGD-----PGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL 1810 Query: 1683 DGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRA 1742 G G +G PGP G PG PG G GKPG G +G PG G G KG++GD + Sbjct: 1811 PGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGA------ 1864 Query: 1743 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPG 1802 SG+ R + + R PG GP GPPG G G PG G Sbjct: 1865 ----------SGREGR---------DGPKGERGAPGILGPQGPPGLPGPVGPPGQG---- 1901 Query: 1803 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPG---------------------- 1840 FPG PG GP G+RG G KGE+G G RGL G PG Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGEQGL--PGERGLRGEPGSVPNVDRLLETAGIKASALREI 1959 Query: 1841 ------------PQGESRTGPPGSTGSRGPPG---PPGRPGNSGIRG------PPGPPGY 1879 P E R GP G +G +GPPG P G PG G++G P GPPG Sbjct: 1960 VETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL 2019 Query: 1880 CDSSQCASIPYNGQGYPG 1897 + P G PG Sbjct: 2020 ALGERGPPGPSGLAGEPG 2037 Score = 215 bits (548), Expect = 3e-55 Identities = 145/341 (42%), Positives = 161/341 (47%), Gaps = 68/341 (19%) Query: 1582 VGPPGPPGPAGGPGAK-----GPRGERGISGA-----IGPPGPRGDIGPPGPQGPPGPQG 1631 VGP G PGP G PG G +GE+G G +G PG +GD G PGP+G G G Sbjct: 2286 VGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG 2345 Query: 1632 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA----- 1685 G PGE G++G G G G PG G PG PGPPGP G GD G G GA Sbjct: 2346 RAGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVG 2404 Query: 1686 ----MGPRGPPGPPGS---------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 1732 GPRG G PG PG G+ GP G PG PG G PG SGLKG+KGD G Sbjct: 2405 FPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG 2464 Query: 1733 -DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGA 1791 + R E I G+ R Q GP G GPPGS G Sbjct: 2465 VGLPGPRGERG------EPGIRGEDGR---------------PGQEGPRGLTGPPGSRGE 2503 Query: 1792 RGEPGPGGRPGFPGTPG----MQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG 1843 RGE G G G G G + GPPG RG G+ GERG G GPRG G PG +G Sbjct: 2504 RGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563 Query: 1844 ESRTGPPGSTGSRGPP------GPPGRPGNSGIRGPPGPPG 1878 G PG GS G P GP G+PG +GI G PG PG Sbjct: 2564 SK--GEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602 Score = 213 bits (541), Expect = 2e-54 Identities = 133/323 (41%), Positives = 150/323 (46%), Gaps = 50/323 (15%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQ 1641 VG G GP G PG G GERG+ GA PG RG +G G QG PG G NG PG Sbjct: 1636 VGEKGDEGPPGDPGLPGKAGERGLRGA---PGVRGPVGEKGDQGDPGEDGRNG--SPGSS 1690 Query: 1642 GRQGMKGDAGEPGLPGR----------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP 1691 G +G +G+ G PG PGR G PG G GP GP GD G G G G G Sbjct: 1691 GPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGF 1750 Query: 1692 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 1751 GPPG G PGV GP+G+ G G G G SGL G+ G G + N A Sbjct: 1751 RGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGP-SGPNGAAGKAGDPGRDG 1809 Query: 1752 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG 1811 + G + + PGP GPPG PG G G+PG G+ G PG PG G Sbjct: 1810 LPG---------------LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDG 1854 Query: 1812 PPGER---------GLPGEKGERGT----GSSGPRGLPGPPGPQGE------SRTGPPGS 1852 GE+ G G KGERG G GP GLPGP GP G+ TGP G Sbjct: 1855 RKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGD 1914 Query: 1853 TGSRGPPGPPGRPGNSGIRGPPG 1875 G G G G PG G+RG PG Sbjct: 1915 RGETGSKGEQGLPGERGLRGEPG 1937 Score = 212 bits (540), Expect = 2e-54 Identities = 125/321 (38%), Positives = 147/321 (45%), Gaps = 46/321 (14%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G G PGP+G G GP G GI G +GPPGP G +GPPG G G +G G+ +PG +G Sbjct: 2413 GEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG 2472 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG-------PPGPP 1695 +G G GE G PG+ G GL GPPG G G++G G G G +G PPGP Sbjct: 2473 ERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR 2532 Query: 1696 GSPGSPGVTGP---SGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLI 1752 G+ G G GP G G GD+G PG G KGE GD+G + + Sbjct: 2533 GAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLG-------- 2584 Query: 1753 SGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP 1812 P + PG PG PG G G RGE G G G G G +G Sbjct: 2585 --------------PQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGV 2630 Query: 1813 PGERGLPGEKGERG----------TGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGP 1858 G GL GEKG++G G G G PG PG G E GP G G G Sbjct: 2631 KGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ 2690 Query: 1859 PGPPGRPGNSGIRGPPGPPGY 1879 PGP G G G RG PG G+ Sbjct: 2691 PGPKGDQGEKGERGTPGIGGF 2711 Score = 207 bits (527), Expect = 8e-53 Identities = 133/326 (40%), Positives = 151/326 (46%), Gaps = 65/326 (19%) Query: 1588 PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMK 1647 P P G KG GE+G G GP G G+ G G +G PGPQGP GL++ GE+G G Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLAL-GERGPPGPS 2030 Query: 1648 GDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPS 1707 G AGEPG PG G PG G G G PG+RG G+ G G +G GPPG PG+PG GP Sbjct: 2031 GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPP 2090 Query: 1708 G------KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 1761 G +PG PG G GP GLKG KG+ G Sbjct: 2091 GPKVSVDEPG-PGLSGEQGPPGLKGAKGEPG----------------------------- 2120 Query: 1762 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 1821 S GP G G PG G RGEPGP G+ G PG PG +G G G PG Sbjct: 2121 -----------SNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGL 2169 Query: 1822 KGERGT-GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNS--------GIR 1871 +G RG G G G PGPPG G GP G +G +G PG G PG G+ Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP 2229 Query: 1872 GPPGPPGYCDSSQCASIPYNGQGYPG 1897 GPPGP G P G PG Sbjct: 2230 GPPGPSGLVG-------PQGSPGLPG 2248 Score = 196 bits (498), Expect = 2e-49 Identities = 142/413 (34%), Positives = 167/413 (40%), Gaps = 103/413 (24%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI---SGAIGPPGPRGDIGPPGPQG 1625 P+ PN G G PG G G GP G G+ G G PG G G PG G Sbjct: 1792 PSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPG 1851 Query: 1626 PPGPQGPNGLS-IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP-----------PGPMGP 1673 G +G G S G +GR G KG+ G PG+ G G PGLPGP PG GP Sbjct: 1852 EDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGP 1911 Query: 1674 PGDRGFTGKDGAMGPRGPPGPPGSPGS--------------------------------- 1700 GDRG TG G G G G G PGS Sbjct: 1912 KGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFL 1971 Query: 1701 ---------PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM---------RA 1742 G +G G PGK G G PG GLKG++GD G + Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSG 2031 Query: 1743 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ------------------PGPPGPPG 1784 +A + + I G R + + R + PGPPGPPG Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091 Query: 1785 P--------PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG---------- 1826 P PG +G +G PG G G PG+ G QGP G+RG+PG KG+RG Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151 Query: 1827 TGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G G RG+ GP G G + GPPG G G PGPPG PG +G GP GP G Sbjct: 2152 PGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSG 2204 Score = 190 bits (482), Expect = 1e-47 Identities = 124/304 (40%), Positives = 144/304 (47%), Gaps = 56/304 (18%) Query: 1598 GPRGERGISGAIGPPGPRGDIGPPGPQGPPG--PQGPNGLSIPGEQGRQGMKGDAGEPGL 1655 GP ++ +SG P P+ P P+G G PGE G +G G G+PGL Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGE--PGEMGLRGQVGPPGDPGL 1276 Query: 1656 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD 1715 PGRTG PG GPPG G+RGF G DG G G G PG+PG+PG+ G G PG GD Sbjct: 1277 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD 1336 Query: 1716 HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 1775 G GP G KGE G G + I + Sbjct: 1337 PGERGPRGPKGEPGAPGQV-------------------------------IGGEGPGLPG 1365 Query: 1776 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP--------GMQGPPG--ERGL-PGEKGE 1824 + G PGP GPPG G G+PGP G PG PGT G +GPPG E G+ PGE G Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425 Query: 1825 RGT-GSSGPRGLPGPPGPQGE---SRTGPPGSTGS------RGPPGPPGRPGNSGIRGPP 1874 G GS GP+G GPPG +GE S G PG G +GP GPPG G G RG P Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485 Query: 1875 GPPG 1878 GP G Sbjct: 1486 GPLG 1489 Score = 178 bits (451), Expect = 5e-44 Identities = 122/319 (38%), Positives = 144/319 (45%), Gaps = 31/319 (9%) Query: 1580 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 1635 DS GPPGP G G G RG RG+ G GP G GD G G +G PG +G GL Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK---------DGAM 1686 + G QG+ G G G+PG PG+ G PG+ G G +G G RG G+ DG Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEK 2640 Query: 1687 GPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQ 1746 G +G GPPG PG G G G+PG PG G PG GL G KGDRG Q + + Sbjct: 2641 GDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRG-FDGQPGPKGDQGE 2699 Query: 1747 VCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPG---PPGPPGSAGARGEPGPGGR--- 1800 E+ G + F P+ S PGPPG P GP G G +GE GP G Sbjct: 2700 KGERGTPG-IGGFPG-----PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVV 2753 Query: 1801 -----PGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGS 1855 PG PG G QG PG G GEKGE RG Q + G ++GS Sbjct: 2754 GAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGS 2813 Query: 1856 RGPPGPPGRPGNSGIRGPP 1874 R P S + P Sbjct: 2814 RPLPSYAADTAGSQLHAVP 2832 Score = 120 bits (300), Expect = 2e-26 Identities = 70/184 (38%), Positives = 104/184 (56%), Gaps = 2/184 (1%) Query: 1158 ADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPA-GIQVSFVQYSDEVKSEFKLNT 1216 ADIVFL D S SIG NF +V F+ V F + A G++ + VQYSD+ ++EF L+ Sbjct: 37 ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96 Query: 1217 YNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDE 1276 + A++ + Y+GGNTRTG A+ + + V + R VPKV +++TDG+SQD Sbjct: 97 LGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA-RPGVPKVCILITDGKSQDL 155 Query: 1277 VKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFV 1336 V AA ++ G +F VG+ + D EL +AS+P+ F V+DF + + V Sbjct: 156 VDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRV 215 Query: 1337 CETA 1340 C TA Sbjct: 216 CTTA 219 Score = 108 bits (269), Expect = 6e-23 Identities = 73/200 (36%), Positives = 83/200 (41%), Gaps = 51/200 (25%) Query: 1714 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSS 1773 G G PG GL+G+ G GD +P Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPG------------------------------LPG----- 1278 Query: 1774 RNQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPGTPGMQGPPGERGLPGEKGE 1824 + G PGP GPPGSA A+GE PG GR G PGTPG G G GLPG +G+ Sbjct: 1279 --RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD 1336 Query: 1825 RGT-GSSGPRGLPGPPGP----QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879 G G GP+G PG PG +G G G G GPPGP G G+ G RGPPG PG Sbjct: 1337 PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396 Query: 1880 CDSSQCASIPYNGQGYPGSG 1899 G PG G Sbjct: 1397 AMKGDKGDRGERGPPGPGEG 1416 Score = 77.4 bits (189), Expect = 1e-13 Identities = 44/105 (41%), Positives = 51/105 (48%), Gaps = 12/105 (11%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 1638 Q G G PG G PG G G+ GPPGP G +GP GP+G G +G G P Sbjct: 2697 QGEKGERGTPGIGGFPGPSGN------DGSAGPPGPPGSVGPRGPEGLQGQKGERG--PP 2748 Query: 1639 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 1683 GE+ + G G PG PG G G PGP GP G G+ T D Sbjct: 2749 GER----VVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDD 2789 Score = 67.4 bits (163), Expect = 1e-10 Identities = 50/179 (27%), Positives = 73/179 (40%), Gaps = 7/179 (3%) Query: 955 PQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPV-GSNEPMEAFVGEM------TSYTL 1007 P+++ +S+ RV W + PV GYK+ Y P+ G +P+ + E+ TS L Sbjct: 235 PRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRL 294 Query: 1008 HNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAAT 1067 L P T Y V V A Y + + ++ T L +L + V W AT Sbjct: 295 RGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGAT 354 Query: 1068 SYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHT 1126 YR+ G Q+ + + S L P TDY VTV GP S+ T Sbjct: 355 GYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMART 413 Score = 64.7 bits (156), Expect = 8e-10 Identities = 48/187 (25%), Positives = 80/187 (42%), Gaps = 3/187 (1%) Query: 31 RAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLN 90 R AD+V L + T R ++ + +GP+ VQ+ L YS P + LN Sbjct: 1050 RGLADVVFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLN 1109 Query: 91 AHRDKKSLLQAVANLPY--KGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKS 148 D +LQ + ++PY GN L + R G R + VL+ D Sbjct: 1110 GSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPL 1169 Query: 149 QDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHA-YNVADFESLSRIVDDL 207 + D+ +P ++ + G+ + +G+ AD +L+ +A D + V D SL + V L Sbjct: 1170 RGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGL 1229 Query: 208 TINLCNS 214 LC + Sbjct: 1230 ATALCQA 1236 >gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo sapiens] Length = 921 Score = 333 bits (854), Expect = 9e-91 Identities = 202/575 (35%), Positives = 274/575 (47%), Gaps = 81/575 (14%) Query: 1344 CPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTAD 1403 CP I + PGF ++ + + + AS + + GS AY++ N PT + Sbjct: 44 CPKIRIGQDDLPGFDLISQFQVDKA--ASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRN 101 Query: 1404 LHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTR 1463 L+P+GLP Y+ + FR+ T + IWQI D K QVG+ + ++++ F K Sbjct: 102 LYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLD 161 Query: 1464 GEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEI 1523 G +QT F + +LF +HK+ I V S +++DC I IK G I DG+ + Sbjct: 162 GSLQTAAFSN--LSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAV 219 Query: 1524 LGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVG 1583 LGKL + S F++Q I C P+ R+ C ++P+R P+ G Sbjct: 220 LGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARIT----PSQTTDERGPPGEQG 275 Query: 1584 PPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQG 1642 PPGPPGP G PG G G+RG G GPPGP G+ G PG G PG G +GL+ P G G Sbjct: 276 PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPG 335 Query: 1643 RQGMKGDAGEPGLPGRTGTPGL--------------------------------PGPPGP 1670 G KG GEPG+PG G PG PGPPGP Sbjct: 336 SIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGP 395 Query: 1671 MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGD 1730 GP G GF D PPG G PG PG+ G G G+ G+ GR G G +G++G+ Sbjct: 396 PGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE 455 Query: 1731 RGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAG 1790 G++ +Q P Q R G G G G+ G Sbjct: 456 LGEVGAQG----------------------------PPGAQGLRGITGIVGDKGEKGARG 487 Query: 1791 ARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGES----- 1845 GEPGP G PG PG G +GPPGE G G++ G+ G RG+PG PGP+G++ Sbjct: 488 LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR-----GAEGARGIPGLPGPKGDTGLPGV 542 Query: 1846 --RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 R G PG G++G PG PG PG++G++G PG PG Sbjct: 543 DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577 Score = 253 bits (647), Expect = 1e-66 Identities = 148/353 (41%), Positives = 177/353 (50%), Gaps = 45/353 (12%) Query: 1578 TQDSVGPPGPPGPAGG---------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 T+ G PGPPG AG PGAKG GE+G +GA G PG G+ G PG QGPPG Sbjct: 554 TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 613 Query: 1629 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--------------- 1672 GP G +PG +G G G G PG G G+PGLPG PGP G Sbjct: 614 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 673 Query: 1673 PPGDRGFTGKDGAMGPRGP------PGPPGS---PGSPGVTGPSGKPGKPGDHGRPGPSG 1723 P G++G +G++G G RG PGP GS PG PG+ GP G G PG G GP G Sbjct: 674 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 733 Query: 1724 LKGEKGDRGDIASQNMMRAVAR--------QVCEQLISGQMNRFNQMLNQIPNDYQSSRN 1775 +G +G++G + R QVC ++I L + + Sbjct: 734 PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 793 Query: 1776 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGL 1835 +PGPPGPPGPPG G G+ G G PG G PG G G +G GEKGERG GP GL Sbjct: 794 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGL 853 Query: 1836 PGP---PGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQC 1885 PG PG G + G G G RGPPG G PG G GPPG PG+C+ + C Sbjct: 854 PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906 Score = 232 bits (591), Expect = 3e-60 Identities = 149/358 (41%), Positives = 174/358 (48%), Gaps = 41/358 (11%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P PN+C + G PG PG G GAKG GE G G G G +G++G G QGPPG Sbjct: 409 PLCPNACPPGRS--GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 466 Query: 1629 PQGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK-- 1682 QG G++ GE+G +G+ G+ G GLPG G G GPPG GP GDRG G Sbjct: 467 AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 526 Query: 1683 -DGAMGPRGPPGPPGS------PGSPGVTGPSGKPGKPGDHGR---------PGPSGLKG 1726 G GP+G G PG PG PG G GKPG PGD G PG G+ G Sbjct: 527 IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG 586 Query: 1727 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 1786 EKG G M + GQ ++ + P SR + GP G PG P Sbjct: 587 EKGSTGAPGKPGQMGNSGKP-------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 639 Query: 1787 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPRGLPGP---P 1839 G G+ G PG G PG PG PGM+G G G PG KGE+G G +G RG G P Sbjct: 640 GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 699 Query: 1840 GPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GP+G + G PG G RGP G G PG G RGPPGP G +P QG PG Sbjct: 700 GPKGSA--GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP-GVQGPPG 754 Score = 212 bits (539), Expect = 3e-54 Identities = 148/393 (37%), Positives = 168/393 (42%), Gaps = 101/393 (25%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---PRGDIG------------------PP 1621 G PG G G PG GP+G+RG GA G PG P+GD G P Sbjct: 499 GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558 Query: 1622 GPQGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 1680 G GPPG G GL +PG G +G+ G+ G G PG+ G G G PG GPPG+ G Sbjct: 559 GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 618 Query: 1681 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 1740 G G G RG GP GSPG PG G G PG PG PGP GL G KGDRG + Sbjct: 619 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPK 675 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG---P 1797 EQ SG+ + R + G G PGP GSAG GEPG P Sbjct: 676 G-------EQGASGEEGEAGE------------RGELGDIGLPGPKGSAGNPGEPGLRGP 716 Query: 1798 GGRPGFPGTPGMQGPPGERGLPGEKGERG------------------------------- 1826 G G PG G +GPPG RG+ GE+G G Sbjct: 717 EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 776 Query: 1827 ------------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGP- 1873 TG G G PGPPGP GE+ G PG G RG PG G PG G+RGP Sbjct: 777 MAASLKRPDSGATGLPGRPGPPGPPGPPGEN--GFPGQMGIRGLPGIKGPPGALGLRGPK 834 Query: 1874 --------PGPPGYCDSSQCASIPYNGQGYPGS 1898 GPPG + +I G P S Sbjct: 835 GDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 867 Score = 107 bits (268), Expect = 8e-23 Identities = 79/245 (32%), Positives = 90/245 (36%), Gaps = 95/245 (38%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL------ 1635 VG PGP G G G +G GERG G IG PGP+G G PG G GP+G GL Sbjct: 669 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 728 Query: 1636 -------SIPGEQGRQGMKGDAGEPGLP------------------------------GR 1658 + GEQG G+ G G PG G Sbjct: 729 RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788 Query: 1659 TGTPGLPGPPGPMGPPGDRGFTGK------------DGAMGPRGPPG---------PPGS 1697 TG PG PGPPGP GPPG+ GF G+ GA+G RGP G PPG Sbjct: 789 TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 848 Query: 1698 -------------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKG 1726 PG G+ G G PG PG G P+ Sbjct: 849 GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 908 Query: 1727 EKGDR 1731 + G R Sbjct: 909 QAGQR 913 Score = 84.3 bits (207), Expect = 1e-15 Identities = 51/121 (42%), Positives = 60/121 (49%), Gaps = 25/121 (20%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG------PRGDIGPPGPQGPPGPQGPNGL- 1635 GPPGPPGP G G G G RG+ G GPPG P+GD+G G +GPPG +GPNGL Sbjct: 796 GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 854 Query: 1636 ---SIPGEQG-----RQGMKGDAGEPGL---------PGRTGTPGLPGPPGPMGPPGDRG 1678 +PG+ G R G G+ G PG+ PG G PG P G R Sbjct: 855 GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 914 Query: 1679 F 1679 F Sbjct: 915 F 915 >gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] Length = 2355 Score = 296 bits (757), Expect = 2e-79 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%) Query: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 513 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 631 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 691 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 750 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 807 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866 +G P+++ + + +E L P Y V++ A GE P Q P+ Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637 Query: 867 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 925 L +S+ +AW+ G V +YR+ YS + D I E P G + LQ L+P + Sbjct: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696 Query: 926 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 985 Y ++V+A+++D + L G ++ + P ++ + T W P + GY++ Sbjct: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755 Query: 986 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043 P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814 Query: 1044 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 1099 + + ++ T + W + T +++ PA+G + T++ S+ TGL Sbjct: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874 Query: 1100 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128 P TDY + ++ N V + T + Sbjct: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903 Score = 286 bits (732), Expect = 1e-76 Identities = 233/843 (27%), Positives = 380/843 (45%), Gaps = 32/843 (3%) Query: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266 + N V P L P+NL + VSW + + Y++ P +G G E Sbjct: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326 V ++S +L P EY V+VY+V +D+ S P+ T P L ++GP TM Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283 Query: 327 HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384 V W P T +++ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V Sbjct: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341 Query: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441 S P+ R+ T L P + D+T ++ V W + Y +R+ PE Sbjct: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399 Query: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501 +E V S S +L +L T Y VS+ A++ ESP + Q++T P +L++ Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 502 VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560 T +WD A V YRIT+ G +S E + G ++T L P Y +++ Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 561 TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619 A+ + D S + + I T+ K P +QV + NS++VKW P+S V Y Sbjct: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572 Query: 620 RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679 R+T P G G +T T G Q + ++ L+P Y ++V + P GE + T Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1631 Query: 680 LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRN 738 ++ + L D ++ + W+ +G +Y++ Y+ G EL P P G + A L+ Sbjct: 1632 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1691 Query: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 L+P + YTV+VV ++ + + T T + +++ TP SL +W P + Sbjct: 1692 LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLT 1750 Query: 799 QYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRT 858 YRV +P + T P + I + ++ V + L+ T Y V++ AL P+ T Sbjct: 1751 GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT 1810 Query: 859 LPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 L S PR RV T +++++W + +++ P G + T P R+ I Sbjct: 1811 LENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1870 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977 LQP T YKI + + ++ + + T + P N+ VSW P + Sbjct: 1871 -TGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRA 1928 Query: 978 PVLGYKIVYKPVGS--NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035 + GY I Y+ GS E + +T T+ L P T Y + V A ++ S PL + Sbjct: 1929 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988 Query: 1036 GTT 1038 T Sbjct: 1989 KKT 1991 Score = 278 bits (711), Expect = 4e-74 Identities = 244/915 (26%), Positives = 394/915 (43%), Gaps = 49/915 (5%) Query: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287 ++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+ Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787 Query: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345 VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847 Query: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404 + T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR Sbjct: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456 P+DL+ +VT + + W P V Y ++ P E + + + R+ T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963 Query: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516 + L Y V AV ES P+TAQ+TT+ + APTNL+ T W + Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022 Query: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576 ++ YR+T + + + NL P + Y VS+ AI ++ S Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075 Query: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634 + + TT P S P N +V T ++ + W PA R+ +++ +PS +G E Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128 Query: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693 + S+V+ L P Y T+ L E PL+ NL + +P T Sbjct: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188 Query: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750 L V W+ + + Y++ P G G + + + NL P Y V+V Sbjct: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248 Query: 751 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPG-PVLQYRVVYSPVDG 809 V + + SDT + +++ N P+++ V W P P + + V YSPV Sbjct: 1249 TVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307 Query: 810 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 869 + + + V L L+P T Y V++ ++Y E P + +T P + Sbjct: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDF 1366 Query: 870 FGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKI 929 T NS +V W + YRI + P VP RN++ L L P T Y + Sbjct: 1367 SDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1426 Query: 930 TVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPV 989 +++A+ + L G TV + P+++ + T +SWD V Y+I Y Sbjct: 1427 SIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGET 1485 Query: 990 GSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLTDQGTTLYLNV 1043 G N P++ F G ++ T+ L P Y + VYA G S P++ T Sbjct: 1486 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP 1545 Query: 1044 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SETSHCFTGLSPD 1101 + ++ + ++ VKW P + T YR+ +P +G + G +T GL P Sbjct: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605 Query: 1102 TDYGVTVFVQTPNLE 1116 +Y V+V+ Q P+ E Sbjct: 1606 VEYVVSVYAQNPSGE 1620 Score = 276 bits (705), Expect = 2e-73 Identities = 253/942 (26%), Positives = 416/942 (44%), Gaps = 62/942 (6%) Query: 218 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 277 PG P N ++E T ++WTP +K+ P GG+ V+ S V+ Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140 Query: 278 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 332 L P EYV + V+ D E P+ T P +L++ D G T+ + Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 333 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 392 TGY ++ P + +EV + + +L P EY V+V V D S P Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258 Query: 393 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 448 ++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 449 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 508 S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375 Query: 509 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 567 W + ++ YRI P S + E + N++ NL P T Y VSI A+ E Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435 Query: 568 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 627 ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY + Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486 Query: 628 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 682 G Q T+ G +++ + LKP YTITV ++ GR +KP++ Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541 Query: 683 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 738 ++V D ++++V+W + Y++ P G GP + + + Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601 Query: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 796 LQP Y VV VY + G + +T + + R + + +S+ + W+ G Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658 Query: 797 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 853 V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D E P Sbjct: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716 Query: 854 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 912 Q +P P +L+ T SLS W + + YR+ +P P+ E P Sbjct: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774 Query: 913 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 971 ++V++ L T Y+++V A+ + G T+ + PP+ ++D T +S Sbjct: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833 Query: 972 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 1030 W + G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S Sbjct: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893 Query: 1031 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 1088 P+ +T ++L+ ++ V W P RA T Y +K P R R Sbjct: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953 Query: 1089 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130 T TGL P T+Y + V N + + ++ T P Sbjct: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995 Score = 256 bits (655), Expect = 1e-67 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%) Query: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 686 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 864 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 923 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 979 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 1037 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 1094 T L + D+ + W SP + YR+ SP DG G E + Sbjct: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688 Query: 1095 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 1140 GL P ++Y V+V ++E P + + PT+ TP Sbjct: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735 Score = 200 bits (508), Expect = 1e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 942 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 999 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 155 bits (391), Expect = 5e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 1025 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 1026 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 1082 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 1083 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 Score = 76.6 bits (187), Expect = 2e-13 Identities = 84/359 (23%), Positives = 144/359 (40%), Gaps = 55/359 (15%) Query: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279 ++ P +++ T + +SW ++++ ++V+ P +G + + S + Sbjct: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1872 Query: 280 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 338 L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG Sbjct: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1932 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 397 YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+ Sbjct: 1933 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990 Query: 398 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 450 VTLP P ++ DV + + PG Y T ++ Sbjct: 1991 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2041 Query: 451 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRG 509 + S + +F + + +PP TA RP P P N+ Sbjct: 2042 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNV------------ 2080 Query: 510 TWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFENLNPNTIYEVSITAI 563 G +S I+WAPF D E I++ DE L F P T ++T + Sbjct: 2081 ----GQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR--VPGTSTSATLTGL 2131 >gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] Length = 2330 Score = 296 bits (757), Expect = 2e-79 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%) Query: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 513 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 631 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 691 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 750 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 807 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866 +G P+++ + + +E L P Y V++ A GE P Q P+ Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637 Query: 867 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 925 L +S+ +AW+ G V +YR+ YS + D I E P G + LQ L+P + Sbjct: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696 Query: 926 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 985 Y ++V+A+++D + L G ++ + P ++ + T W P + GY++ Sbjct: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755 Query: 986 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043 P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814 Query: 1044 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 1099 + + ++ T + W + T +++ PA+G + T++ S+ TGL Sbjct: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874 Query: 1100 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128 P TDY + ++ N V + T + Sbjct: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903 Score = 286 bits (733), Expect = 1e-76 Identities = 233/844 (27%), Positives = 381/844 (45%), Gaps = 32/844 (3%) Query: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266 + N V P L P+NL + VSW + + Y++ P +G G E Sbjct: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326 V ++S +L P EY V+VY+V +D+ S P+ T P L ++GP TM Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283 Query: 327 HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384 V W P T +++ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V Sbjct: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341 Query: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441 S P+ R+ T L P + D+T ++ V W + Y +R+ PE Sbjct: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399 Query: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501 +E V S S +L +L T Y VS+ A++ ESP + Q++T P +L++ Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 502 VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560 T +WD A V YRIT+ G +S E + G ++T L P Y +++ Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 561 TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619 A+ + D S + + I T+ K P +QV + NS++VKW P+S V Y Sbjct: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572 Query: 620 RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679 R+T P G G +T T G Q + ++ L+P Y ++V + P GE + T Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1631 Query: 680 LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRN 738 ++ + L D ++ + W+ +G +Y++ Y+ G EL P P G + A L+ Sbjct: 1632 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1691 Query: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 L+P + YTV+VV ++ + + T T + +++ TP SL +W P + Sbjct: 1692 LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLT 1750 Query: 799 QYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRT 858 YRV +P + T P + I + ++ V + L+ T Y V++ AL P+ T Sbjct: 1751 GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT 1810 Query: 859 LPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 L S PR RV T +++++W + +++ P G + T P R+ I Sbjct: 1811 LENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1870 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977 LQP T YKI + + ++ + + T + P N+ VSW P + Sbjct: 1871 -TGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRA 1928 Query: 978 PVLGYKIVYKPVGS--NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035 + GY I Y+ GS E + +T T+ L P T Y + V A ++ S PL + Sbjct: 1929 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988 Query: 1036 GTTL 1039 T+ Sbjct: 1989 KKTV 1992 Score = 278 bits (711), Expect = 4e-74 Identities = 244/915 (26%), Positives = 394/915 (43%), Gaps = 49/915 (5%) Query: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287 ++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+ Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787 Query: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345 VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847 Query: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404 + T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR Sbjct: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456 P+DL+ +VT + + W P V Y ++ P E + + + R+ T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963 Query: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516 + L Y V AV ES P+TAQ+TT+ + APTNL+ T W + Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022 Query: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576 ++ YR+T + + + NL P + Y VS+ AI ++ S Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075 Query: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634 + + TT P S P N +V T ++ + W PA R+ +++ +PS +G E Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128 Query: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693 + S+V+ L P Y T+ L E PL+ NL + +P T Sbjct: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188 Query: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750 L V W+ + + Y++ P G G + + + NL P Y V+V Sbjct: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248 Query: 751 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPG-PVLQYRVVYSPVDG 809 V + + SDT + +++ N P+++ V W P P + + V YSPV Sbjct: 1249 TVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307 Query: 810 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 869 + + + V L L+P T Y V++ ++Y E P + +T P + Sbjct: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDF 1366 Query: 870 FGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKI 929 T NS +V W + YRI + P VP RN++ L L P T Y + Sbjct: 1367 SDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1426 Query: 930 TVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPV 989 +++A+ + L G TV + P+++ + T +SWD V Y+I Y Sbjct: 1427 SIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGET 1485 Query: 990 GSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLTDQGTTLYLNV 1043 G N P++ F G ++ T+ L P Y + VYA G S P++ T Sbjct: 1486 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP 1545 Query: 1044 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SETSHCFTGLSPD 1101 + ++ + ++ VKW P + T YR+ +P +G + G +T GL P Sbjct: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605 Query: 1102 TDYGVTVFVQTPNLE 1116 +Y V+V+ Q P+ E Sbjct: 1606 VEYVVSVYAQNPSGE 1620 Score = 277 bits (709), Expect = 6e-74 Identities = 256/949 (26%), Positives = 419/949 (44%), Gaps = 63/949 (6%) Query: 218 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 277 PG P N ++E T ++WTP +K+ P GG+ V+ S V+ Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140 Query: 278 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 332 L P EYV + V+ D E P+ T P +L++ D G T+ + Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 333 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 392 TGY ++ P + +EV + + +L P EY V+V V D S P Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258 Query: 393 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 448 ++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 449 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 508 S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375 Query: 509 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 567 W + ++ YRI P S + E + N++ NL P T Y VSI A+ E Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435 Query: 568 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 627 ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY + Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486 Query: 628 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 682 G Q T+ G +++ + LKP YTITV ++ GR +KP++ Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541 Query: 683 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 738 ++V D ++++V+W + Y++ P G GP + + + Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601 Query: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 796 LQP Y VV VY + G + +T + + R + + +S+ + W+ G Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658 Query: 797 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 853 V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D E P Sbjct: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716 Query: 854 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 912 Q +P P +L+ T SLS W + + YR+ +P P+ E P Sbjct: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774 Query: 913 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 971 ++V++ L T Y+++V A+ + G T+ + PP+ ++D T +S Sbjct: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833 Query: 972 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 1030 W + G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S Sbjct: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893 Query: 1031 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 1088 P+ +T ++L+ ++ V W P RA T Y +K P R R Sbjct: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953 Query: 1089 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 1137 T TGL P T+Y + V N + + + TV+ T T P Sbjct: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2001 Score = 256 bits (655), Expect = 1e-67 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%) Query: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 686 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 864 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 923 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 979 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 1037 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 1094 T L + D+ + W SP + YR+ SP DG G E + Sbjct: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688 Query: 1095 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 1140 GL P ++Y V+V ++E P + + PT+ TP Sbjct: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735 Score = 200 bits (508), Expect = 1e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 942 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 999 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 155 bits (391), Expect = 5e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 1025 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 1026 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 1082 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 1083 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 >gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] Length = 2421 Score = 291 bits (744), Expect = 5e-78 Identities = 256/956 (26%), Positives = 430/956 (44%), Gaps = 58/956 (6%) Query: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266 + N V P L P+NL + VSW + + Y++ P +G G E Sbjct: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326 V ++S +L P EY V+VY+V +D+ S P+ T + L+ D+ +++ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283 Query: 327 HVQWQPVGGAT--GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384 ++W P+ +T GY ++ + P E + +V +T L P +Y ++V + Sbjct: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITL 1341 Query: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EE 441 ++ S P T+ + T +P P DL+ ++ TM V W P P + ++VRY EE Sbjct: 1342 INGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400 Query: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501 DV E+ + S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + ++ Sbjct: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSD 1459 Query: 502 VTSEGFRGTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSI 560 +T+ F W + ++ YRI P S + E + N++ NL P T Y VSI Sbjct: 1460 ITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1519 Query: 561 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 620 A+ E ES LIG + T+ + PR+L+V AT SL + WD + V+ YR Sbjct: 1520 VALNGRE-ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYR 1570 Query: 621 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680 ITY + G Q T+ G +++ + LKP YTITV ++ GR +KP+ Sbjct: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPI 1625 Query: 681 NT--------VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNT 731 + ++V D ++++V+W + Y++ P G GP + + Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685 Query: 732 NYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVR 789 + LQP Y VV VY + G + +T + + R + + +S+ + Sbjct: 1686 TEMTIEGLQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIA 1742 Query: 790 WDPAPGPVLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDG 847 W+ G V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D Sbjct: 1743 WESPQGQVSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800 Query: 848 EGNPS-PAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDE 905 E P Q +P P +L+ T SLS W + + YR+ +P P+ E Sbjct: 1801 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1858 Query: 906 YTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEW 964 P ++V++ L T Y+++V A+ + G T+ + PP+ ++D Sbjct: 1859 INLAPDS-SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917 Query: 965 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQ 1023 T +SW + G+++ P P++ + ++ SYT+ L P T Y + +Y Sbjct: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977 Query: 1024 YDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRG 1081 D+ S P+ +T ++L+ ++ V W P RA T Y +K P R Sbjct: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037 Query: 1082 QEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 1137 R T TGL P T+Y + V N + + + TV+ T T P Sbjct: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2092 Score = 261 bits (667), Expect = 5e-69 Identities = 250/933 (26%), Positives = 398/933 (42%), Gaps = 51/933 (5%) Query: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287 ++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+ Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787 Query: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345 VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847 Query: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404 + T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR Sbjct: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456 P+DL+ +VT + + W P V Y ++ P E + + + R+ T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963 Query: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516 + L Y V AV ES P+TAQ+TT+ + APTNL+ T W + Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022 Query: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576 ++ YR+T + + + NL P + Y VS+ AI ++ S Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075 Query: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634 + + TT P S P N +V T ++ + W PA R+ +++ +PS +G E Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128 Query: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693 + S+V+ L P Y T+ L E PL+ NL + +P T Sbjct: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188 Query: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750 L V W+ + + Y++ P G G + + + NL P Y V+V Sbjct: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248 Query: 751 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPA-PGPVLQYRVVYSPVDG 809 V + + SDT + L ++ + T +S+ +RW P ++ YR+ Sbjct: 1249 TVKDDKESVPISDTIIPEVPQLT-DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGE 1307 Query: 810 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 869 P V + + L P Y ++++ L + GE P+ +T P +LR Sbjct: 1308 GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-PPPTDLRF 1366 Query: 870 FGETTNSLSVAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 928 +++ V W + + + YSP + ++ N V+L L P T Y Sbjct: 1367 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426 Query: 929 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 988 ++V +VYE + L G +T GL P I SD F V W + + GY+I + P Sbjct: 1427 VSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1485 Query: 989 VG-SNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL 1046 S P E V S TL NL P T Y V++ A S L Q +T+ DL Sbjct: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545 Query: 1047 KTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDY 1104 + + + W +P YR+ G QE TV GS+++ +GL P DY Sbjct: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605 Query: 1105 GVTVFVQTPNLEGPG----VSVKEHTTV-KPTE 1132 +TV+ T + P +S+ T + KP++ Sbjct: 1606 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638 Score = 259 bits (661), Expect = 2e-68 Identities = 236/916 (25%), Positives = 391/916 (42%), Gaps = 55/916 (6%) Query: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512 S + +L Y VSV V D+ ES P++ +T P VP T+L ++T W Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSSIGLRWT 1288 Query: 513 H-GASDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570 +S + YRIT G + E ++ L P Y++S+ + Sbjct: 1289 PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITL------- 1341 Query: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGE 629 + G E LT Q P +L+ N +++ V W P S + + + Y P E Sbjct: 1342 --INGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE 1399 Query: 630 GNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVY 689 + +I N+VVL L P T Y ++VSS+Y E + GR KT L++ + Sbjct: 1400 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFS 1458 Query: 690 DPSTSTLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTV 747 D + ++ V W Y++ + P +G P E +P + N L NL P T Y V Sbjct: 1459 DITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVV 1517 Query: 748 TVVPVYTEGDGGRTSDT----GRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803 ++V + GR ++ + + R+++V TP SL + WD V YR+ Sbjct: 1518 SIVAL-----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572 Query: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS- 862 Y G P + VPG+ + L P Y++ + A+ G+ SPA + + + Sbjct: 1573 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINY 1629 Query: 863 -----GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 P ++V NS+SV W + PV YR+ +P G + T + + Sbjct: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977 ++ LQP Y ++V A G+ L T + P+ + +D +++W+ Sbjct: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQG 1748 Query: 978 PVLGYKIVYKPV--GSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035 V Y++ Y G +E A GE + L L P + Y V+V A +D S PL Sbjct: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808 Query: 1036 GTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSH 1093 +T TDLK Q+ + +W+P T YR++++P + T +EI + +S Sbjct: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868 Query: 1094 CFTGLSPDTDYGVTVF 1109 +GL T Y V+V+ Sbjct: 1869 VVSGLMVATKYEVSVY 1884 Score = 244 bits (622), Expect = 8e-64 Identities = 235/925 (25%), Positives = 386/925 (41%), Gaps = 55/925 (5%) Query: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685 G +GN + Q+S L P Y ++V ++ D E ++ + + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPEVPQLTD 1272 Query: 686 LRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPI-----PGNTNYAILRNLQ 740 L D + S++ +RW + AAG E +PI + Y + L+ Sbjct: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDFVDSSVGYYTVTGLE 1329 Query: 741 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPG-PVLQ 799 P Y ++V+ + G+ T+ T +T + +++ N P+++ V W P P + Sbjct: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388 Query: 800 YRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL 859 + V YSPV + + + V L L+P T Y V++ ++Y E P + +T Sbjct: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1447 Query: 860 PRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQ 919 P + T NS +V W + YRI + P VP RN++ L Sbjct: 1448 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507 Query: 920 PLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPV 979 L P T Y ++++A+ + L G TV + P+++ + T +SWD V Sbjct: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTV 1566 Query: 980 LGYKIVYKPVGSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLT 1033 Y+I Y G N P++ F G ++ T+ L P Y + VYA G S P++ Sbjct: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626 Query: 1034 DQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SET 1091 T + ++ + ++ VKW P + T YR+ +P +G + G +T Sbjct: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686 Query: 1092 SHCFTGLSPDTDYGVTVFVQTPNLE 1116 GL P +Y V+V+ Q P+ E Sbjct: 1687 EMTIEGLQPTVEYVVSVYAQNPSGE 1711 Score = 201 bits (510), Expect = 7e-51 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%) Query: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 942 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 997 ++ T+ PQ +S D + + W P + S ++GY+I G P+ E Sbjct: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314 Query: 998 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 1056 FV YT+ L P YD++V + G S P T T TDL+ IG DT Sbjct: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374 Query: 1057 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 1108 V W+P + T++ ++ SP E+++ S+ + T L P T+Y V+V Sbjct: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429 Score = 152 bits (385), Expect = 2e-36 Identities = 147/639 (23%), Positives = 250/639 (39%), Gaps = 47/639 (7%) Query: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 1025 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 1026 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 1082 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 1083 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVS 1121 E V ++S F LSP +Y V+V+ + E +S Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260 Score = 65.9 bits (159), Expect = 4e-10 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%) Query: 847 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 900 GE + P Q T P S GP + VF T NS + W+ + +Y + + P Sbjct: 595 GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650 Query: 901 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 942 + T+PG N+ ++ L+P Y+ +I++ + G Sbjct: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710 Query: 943 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 1000 +TG L + +++ + F VSW + V G+++ Y+ G Sbjct: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770 Query: 1001 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 1059 TS + +L P Y VNVY + G S+ L+ TT D Q+ + V+ Sbjct: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830 Query: 1060 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 1118 WS P T YR+ SP+ E+ + + S + L P Y +T++ N E Sbjct: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890 Query: 1119 GVSVKEHTTVKPTEAPTEPP 1138 V +++ TT P P Sbjct: 891 PVVIQQETTGTPRSDTVPSP 910 >gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] Length = 2477 Score = 289 bits (740), Expect = 2e-77 Identities = 253/949 (26%), Positives = 427/949 (44%), Gaps = 57/949 (6%) Query: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266 + N V P L P+NL + VSW + + Y++ P +G G E Sbjct: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326 V ++S +L P EY V+VY+V +D+ S P+ T + L+ D+ +++ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283 Query: 327 HVQWQPVGGAT--GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384 ++W P+ +T GY ++ + P E + +V +T L P +Y ++V + Sbjct: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITL 1341 Query: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EE 441 ++ S P T+ + T +P P DL+ ++ TM V W P P + ++VRY EE Sbjct: 1342 INGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400 Query: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501 DV E+ + S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + ++ Sbjct: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSD 1459 Query: 502 VTSEGFRGTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSI 560 +T+ F W + ++ YRI P S + E + N++ NL P T Y VSI Sbjct: 1460 ITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1519 Query: 561 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 620 A+ E ES LIG + T+ + PR+L+V AT SL + WD + V+ YR Sbjct: 1520 VALNGRE-ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYR 1570 Query: 621 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680 ITY + G Q T+ G +++ + LKP YTITV ++ GR +KP+ Sbjct: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPI 1625 Query: 681 NT--------VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNT 731 + ++V D ++++V+W + Y++ P G GP + + Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685 Query: 732 NYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVR 789 + LQP Y VV VY + G + +T + + R + + +S+ + Sbjct: 1686 TEMTIEGLQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIA 1742 Query: 790 WDPAPGPVLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDG 847 W+ G V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D Sbjct: 1743 WESPQGQVSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800 Query: 848 EGNPS-PAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDE 905 E P Q +P P +L+ T SLS W + + YR+ +P P+ E Sbjct: 1801 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1858 Query: 906 YTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEW 964 P ++V++ L T Y+++V A+ + G T+ + PP+ ++D Sbjct: 1859 INLAPDS-SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917 Query: 965 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQ 1023 T +SW + G+++ P P++ + ++ SYT+ L P T Y + +Y Sbjct: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977 Query: 1024 YDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRG 1081 D+ S P+ +T ++L+ ++ V W P RA T Y +K P R Sbjct: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037 Query: 1082 QEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130 R T TGL P T+Y + V N + + ++ T P Sbjct: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086 Score = 261 bits (667), Expect = 5e-69 Identities = 250/933 (26%), Positives = 398/933 (42%), Gaps = 51/933 (5%) Query: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287 ++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+ Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787 Query: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345 VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847 Query: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404 + T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR Sbjct: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456 P+DL+ +VT + + W P V Y ++ P E + + + R+ T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963 Query: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516 + L Y V AV ES P+TAQ+TT+ + APTNL+ T W + Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022 Query: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576 ++ YR+T + + + NL P + Y VS+ AI ++ S Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075 Query: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634 + + TT P S P N +V T ++ + W PA R+ +++ +PS +G E Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128 Query: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693 + S+V+ L P Y T+ L E PL+ NL + +P T Sbjct: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188 Query: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750 L V W+ + + Y++ P G G + + + NL P Y V+V Sbjct: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248 Query: 751 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPA-PGPVLQYRVVYSPVDG 809 V + + SDT + L ++ + T +S+ +RW P ++ YR+ Sbjct: 1249 TVKDDKESVPISDTIIPEVPQLT-DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGE 1307 Query: 810 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 869 P V + + L P Y ++++ L + GE P+ +T P +LR Sbjct: 1308 GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-PPPTDLRF 1366 Query: 870 FGETTNSLSVAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 928 +++ V W + + + YSP + ++ N V+L L P T Y Sbjct: 1367 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426 Query: 929 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 988 ++V +VYE + L G +T GL P I SD F V W + + GY+I + P Sbjct: 1427 VSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1485 Query: 989 VG-SNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL 1046 S P E V S TL NL P T Y V++ A S L Q +T+ DL Sbjct: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545 Query: 1047 KTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDY 1104 + + + W +P YR+ G QE TV GS+++ +GL P DY Sbjct: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605 Query: 1105 GVTVFVQTPNLEGPG----VSVKEHTTV-KPTE 1132 +TV+ T + P +S+ T + KP++ Sbjct: 1606 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638 Score = 259 bits (661), Expect = 2e-68 Identities = 236/916 (25%), Positives = 391/916 (42%), Gaps = 55/916 (6%) Query: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512 S + +L Y VSV V D+ ES P++ +T P VP T+L ++T W Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSSIGLRWT 1288 Query: 513 H-GASDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570 +S + YRIT G + E ++ L P Y++S+ + Sbjct: 1289 PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITL------- 1341 Query: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGE 629 + G E LT Q P +L+ N +++ V W P S + + + Y P E Sbjct: 1342 --INGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE 1399 Query: 630 GNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVY 689 + +I N+VVL L P T Y ++VSS+Y E + GR KT L++ + Sbjct: 1400 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFS 1458 Query: 690 DPSTSTLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTV 747 D + ++ V W Y++ + P +G P E +P + N L NL P T Y V Sbjct: 1459 DITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVV 1517 Query: 748 TVVPVYTEGDGGRTSDT----GRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803 ++V + GR ++ + + R+++V TP SL + WD V YR+ Sbjct: 1518 SIVAL-----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572 Query: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS- 862 Y G P + VPG+ + L P Y++ + A+ G+ SPA + + + Sbjct: 1573 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINY 1629 Query: 863 -----GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 P ++V NS+SV W + PV YR+ +P G + T + + Sbjct: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977 ++ LQP Y ++V A G+ L T + P+ + +D +++W+ Sbjct: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQG 1748 Query: 978 PVLGYKIVYKPV--GSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035 V Y++ Y G +E A GE + L L P + Y V+V A +D S PL Sbjct: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808 Query: 1036 GTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSH 1093 +T TDLK Q+ + +W+P T YR++++P + T +EI + +S Sbjct: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868 Query: 1094 CFTGLSPDTDYGVTVF 1109 +GL T Y V+V+ Sbjct: 1869 VVSGLMVATKYEVSVY 1884 Score = 244 bits (622), Expect = 8e-64 Identities = 235/925 (25%), Positives = 386/925 (41%), Gaps = 55/925 (5%) Query: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685 G +GN + Q+S L P Y ++V ++ D E ++ + + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPEVPQLTD 1272 Query: 686 LRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPI-----PGNTNYAILRNLQ 740 L D + S++ +RW + AAG E +PI + Y + L+ Sbjct: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDFVDSSVGYYTVTGLE 1329 Query: 741 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPG-PVLQ 799 P Y ++V+ + G+ T+ T +T + +++ N P+++ V W P P + Sbjct: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388 Query: 800 YRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL 859 + V YSPV + + + V L L+P T Y V++ ++Y E P + +T Sbjct: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1447 Query: 860 PRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQ 919 P + T NS +V W + YRI + P VP RN++ L Sbjct: 1448 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507 Query: 920 PLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPV 979 L P T Y ++++A+ + L G TV + P+++ + T +SWD V Sbjct: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTV 1566 Query: 980 LGYKIVYKPVGSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLT 1033 Y+I Y G N P++ F G ++ T+ L P Y + VYA G S P++ Sbjct: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626 Query: 1034 DQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SET 1091 T + ++ + ++ VKW P + T YR+ +P +G + G +T Sbjct: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686 Query: 1092 SHCFTGLSPDTDYGVTVFVQTPNLE 1116 GL P +Y V+V+ Q P+ E Sbjct: 1687 EMTIEGLQPTVEYVVSVYAQNPSGE 1711 Score = 201 bits (510), Expect = 7e-51 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%) Query: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 942 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 997 ++ T+ PQ +S D + + W P + S ++GY+I G P+ E Sbjct: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314 Query: 998 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 1056 FV YT+ L P YD++V + G S P T T TDL+ IG DT Sbjct: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374 Query: 1057 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 1108 V W+P + T++ ++ SP E+++ S+ + T L P T+Y V+V Sbjct: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429 Score = 152 bits (385), Expect = 2e-36 Identities = 147/639 (23%), Positives = 250/639 (39%), Gaps = 47/639 (7%) Query: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 1025 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 1026 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 1082 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 1083 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVS 1121 E V ++S F LSP +Y V+V+ + E +S Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260 Score = 76.3 bits (186), Expect = 3e-13 Identities = 87/374 (23%), Positives = 149/374 (39%), Gaps = 54/374 (14%) Query: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279 ++ P +++ T + +SW ++++ ++V+ P +G + + S + Sbjct: 1904 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963 Query: 280 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 338 L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG Sbjct: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 2023 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 397 YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+ Sbjct: 2024 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 2081 Query: 398 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 450 VTLP P ++ DV + + PG Y T ++ Sbjct: 2082 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2132 Query: 451 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTN----LKITEVTSE 505 + S + +F + + +PP TA RP P P N ++I + E Sbjct: 2133 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183 Query: 506 -----------GFRGTWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFEN 549 G G +S I+WAPF D E I++ DE L F Sbjct: 2184 DVDYHLYPHGPGLNPNASTGQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR- 2240 Query: 550 LNPNTIYEVSITAI 563 P T ++T + Sbjct: 2241 -VPGTSTSATLTGL 2253 Score = 65.9 bits (159), Expect = 4e-10 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%) Query: 847 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 900 GE + P Q T P S GP + VF T NS + W+ + +Y + + P Sbjct: 595 GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650 Query: 901 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 942 + T+PG N+ ++ L+P Y+ +I++ + G Sbjct: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710 Query: 943 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 1000 +TG L + +++ + F VSW + V G+++ Y+ G Sbjct: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770 Query: 1001 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 1059 TS + +L P Y VNVY + G S+ L+ TT D Q+ + V+ Sbjct: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830 Query: 1060 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 1118 WS P T YR+ SP+ E+ + + S + L P Y +T++ N E Sbjct: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890 Query: 1119 GVSVKEHTTVKPTEAPTEPP 1138 V +++ TT P P Sbjct: 891 PVVIQQETTGTPRSDTVPSP 910 >gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] Length = 2296 Score = 281 bits (720), Expect = 3e-75 Identities = 251/940 (26%), Positives = 402/940 (42%), Gaps = 50/940 (5%) Query: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287 ++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+ Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787 Query: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345 VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847 Query: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404 + T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR Sbjct: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456 P+DL+ +VT + + W P V Y ++ P E + + + R+ T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963 Query: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516 + L Y V AV ES P+TAQ+TT+ + APTNL+ T W + Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022 Query: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576 ++ YR+T + + + NL P + Y VS+ AI ++ S Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075 Query: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634 + + TT P S P N +V T ++ + W PA R+ +++ +PS +G E Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128 Query: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693 + S+V+ L P Y T+ L E PL+ NL + +P T Sbjct: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188 Query: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750 L V W+ + + Y++ P G G + + + NL P Y V+V Sbjct: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248 Query: 751 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPG-PVLQYRVVYSPVDG 809 V + + SDT + +++ N P+++ V W P P + + V YSPV Sbjct: 1249 TVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1307 Query: 810 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 869 + + + V L L+P T Y V++ ++Y E P + +T P + Sbjct: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDF 1366 Query: 870 FGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKI 929 T NS +V W + YRI + P VP RN++ L L P T Y + Sbjct: 1367 SDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1426 Query: 930 TVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPV 989 +++A+ + L G TV + P+++ + T +SWD V Y+I Y Sbjct: 1427 SIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGET 1485 Query: 990 GSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLTDQGTTLYLNV 1043 G N P++ F G ++ T+ L P Y + VYA G S P++ T Sbjct: 1486 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP 1545 Query: 1044 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SETSHCFTGLSPD 1101 + ++ + ++ VKW P + T YR+ +P +G + G +T GL P Sbjct: 1546 SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605 Query: 1102 TDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 1140 +Y V+V+ Q P+ E P V T PT+ TP Sbjct: 1606 VEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTP 1645 Score = 281 bits (719), Expect = 4e-75 Identities = 240/929 (25%), Positives = 404/929 (43%), Gaps = 39/929 (4%) Query: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 513 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 631 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 691 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 750 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 807 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866 +G P+++ + + +E L P Y V++ A GE P Q P + Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637 Query: 867 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 925 L+ T SLS W + + YR+ +P P+ E P ++V++ L T Sbjct: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696 Query: 926 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 984 Y+++V A+ + G T+ + PP+ ++D T +SW + G+++ Sbjct: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756 Query: 985 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043 P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T Sbjct: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816 Query: 1044 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 1101 ++L+ ++ V W P RA T Y +K P R R T TGL P Sbjct: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876 Query: 1102 TDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130 T+Y + V N + + ++ T P Sbjct: 1877 TEYTIYVIALKNNQKSEPLIGRKKTDELP 1905 Score = 262 bits (670), Expect = 2e-69 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%) Query: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 686 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 864 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 923 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 979 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 1037 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 1094 T TDLK Q+ + +W+P T YR++++P + T +EI + +S Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688 Query: 1095 FTGLSPDTDYGVTVF 1109 +GL T Y V+V+ Sbjct: 1689 VSGLMVATKYEVSVY 1703 Score = 245 bits (626), Expect = 3e-64 Identities = 246/941 (26%), Positives = 389/941 (41%), Gaps = 67/941 (7%) Query: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266 + N V P L P+NL + VSW + + Y++ P +G G E Sbjct: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326 V ++S +L P EY V+VY+V +D+ S P+ T P L ++GP TM Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283 Query: 327 HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384 V W P T +++ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V Sbjct: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341 Query: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441 S P+ R+ T L P + D+T ++ V W + Y +R+ PE Sbjct: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399 Query: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501 +E V S S +L +L T Y VS+ A++ ESP + Q++T P +L++ Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 502 VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560 T +WD A V YRIT+ G +S E + G ++T L P Y +++ Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 561 TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619 A+ + D S + + I T+ K P +QV + NS++VKW P+S V Y Sbjct: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572 Query: 620 RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679 R+T P G G +T T G Q + ++ L+P Y ++V + P GE + T Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-T 1631 Query: 680 LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRN 738 + +L+ + ++L+ +W Y++ P GP + + + +++ ++ Sbjct: 1632 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1691 Query: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPV 797 L T Y V+V + TL R +V + T ++ + W + Sbjct: 1692 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1751 Query: 798 LQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 ++V P +G P + + P + R + L P T Y + L L + +P Sbjct: 1752 TGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV- 916 T P NLR T NSL V+W + Y I Y P + VP R V Sbjct: 1811 T-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVT 1866 Query: 917 --ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGL-----LPPQNIH---ISDEWYT 966 + L+P T Y I VIA+ + L G +T L LP N+H I D T Sbjct: 1867 EATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPST 1926 Query: 967 RFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNL---NPSTT-------- 1015 + + P G I +P VG+ + H P TT Sbjct: 1927 VQKTPFVTHPGYDTGNGIQLPGTSGQQPS---VGQQMIFEEHGFRRTTPPTTATPIRHRP 1983 Query: 1016 --YDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL----KTYQIGWDTFCVKWSPHRAATSY 1069 Y NV + G +P D LY + L T Q + W+P + + Y Sbjct: 1984 RPYPPNVGEEIQIG-HIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEY 2042 Query: 1070 RLKLSPADGTRGQEITVR--GSETSHCFTGLSPDTDYGVTV 1108 + P GT + + R G+ TS TGL+ Y + V Sbjct: 2043 IISCHPV-GTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2082 Score = 200 bits (508), Expect = 1e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 942 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 999 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 155 bits (391), Expect = 5e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 1025 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 1026 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 1082 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 1083 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 >gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] Length = 2176 Score = 281 bits (718), Expect = 6e-75 Identities = 238/913 (26%), Positives = 398/913 (43%), Gaps = 39/913 (4%) Query: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 513 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 631 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 691 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 750 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 807 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866 +G P+++ + + +E L P Y V++ A GE P Q P + Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637 Query: 867 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 925 L+ T SLS W + + YR+ +P P+ E P ++V++ L T Sbjct: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696 Query: 926 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 984 Y+++V A+ + G T+ + PP+ ++D T +SW + G+++ Sbjct: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756 Query: 985 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043 P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T Sbjct: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816 Query: 1044 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 1101 ++L+ ++ V W P RA T Y +K P R R T TGL P Sbjct: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876 Query: 1102 TDYGVTVFVQTPN 1114 T+Y + V N Sbjct: 1877 TEYTIYVIALKNN 1889 Score = 273 bits (698), Expect = 1e-72 Identities = 240/929 (25%), Positives = 400/929 (43%), Gaps = 47/929 (5%) Query: 223 APSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS--GGKRQEFYVSRMETSTVLKDL 280 +P +L E T + WTPP +V Y+V+ PV+ G Q +SR T + L Sbjct: 909 SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGL 967 Query: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TGY 339 P Y V++V S+PL + T +L + +T+ V+W P TGY Sbjct: 968 SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGY 1027 Query: 340 ILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVT 399 L+ V T +P++ +GP+V+ L +L P +EY V++ A+ + S T T Sbjct: 1028 RLT---VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084 Query: 400 LPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKD 459 L +VT +T+ + W P P K VR E +EV D S Sbjct: 1085 LQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLT 1144 Query: 460 LFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEG-FRGTWDHGAS-D 517 + +YT+ V E ++P V T P+ PTNL + G +W+ + D Sbjct: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPD 1202 Query: 518 VSLYRITWAPFGSS--DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 575 ++ YRIT P + +E +++ D+++ F+NL+P Y VS+ + D+ Sbjct: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE------- 1255 Query: 576 SERTLPILTTQAPK-SGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGEGNEQ 633 ++PI T P P +L+ N +++ V W P S + + + Y P E + Sbjct: 1256 ---SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312 Query: 634 TTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPST 693 +I N+VVL L P T Y ++VSS+Y E + GR KT L++ + D + Sbjct: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITA 1371 Query: 694 STLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVP 751 ++ V W Y++ + P +G P E +P + N L NL P T Y V++V Sbjct: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVVSIVA 1430 Query: 752 VYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTR 811 + + T+ + R+++V TP SL + WD V YR+ Y G Sbjct: 1431 LNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNS 1489 Query: 812 PSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS------GPR 865 P + VPG+ + L P Y++ + A+ G+ SPA + + + P Sbjct: 1490 PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINYRTEIDKPS 1546 Query: 866 NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 925 ++V NS+SV W + PV YR+ +P G + T + + ++ LQP Sbjct: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1606 Query: 926 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 985 Y ++V A G+ L T + P ++ + T W P + GY++ Sbjct: 1607 EYVVSVYAQNPSGESQPLVQTAVTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1665 Query: 986 YKPVGSNEPMEAF--VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043 P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV Sbjct: 1666 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1724 Query: 1044 TDLKTYQIG---WDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 1099 + + ++ T + W + T +++ PA+G + T++ S+ TGL Sbjct: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1784 Query: 1100 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128 P TDY + ++ N V + T + Sbjct: 1785 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1813 Score = 262 bits (670), Expect = 2e-69 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%) Query: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 686 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 864 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 923 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 979 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 1037 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 1094 T TDLK Q+ + +W+P T YR++++P + T +EI + +S Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688 Query: 1095 FTGLSPDTDYGVTVF 1109 +GL T Y V+V+ Sbjct: 1689 VSGLMVATKYEVSVY 1703 Score = 260 bits (665), Expect = 8e-69 Identities = 246/918 (26%), Positives = 400/918 (43%), Gaps = 69/918 (7%) Query: 218 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 277 PG P N ++E T ++WTP +K+ P GG+ V+ S V+ Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140 Query: 278 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 332 L P EYV + V+ D E P+ T P +L++ D G T+ + Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 333 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 392 TGY ++ P + +EV + + +L P EY V+V V D S P Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258 Query: 393 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 448 ++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 449 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 508 S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375 Query: 509 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 567 W + ++ YRI P S + E + N++ NL P T Y VSI A+ E Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435 Query: 568 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 627 ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY + Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486 Query: 628 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 682 G Q T+ G +++ + LKP YTITV ++ GR +KP++ Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541 Query: 683 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 738 ++V D ++++V+W + Y++ P G GP + + + Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601 Query: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 796 LQP Y VV VY + G + +T + + +++ TP SL +W P Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1658 Query: 797 VLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQG 856 + YRV +P + T P + I + ++ V + L+ T Y V++ AL P+ Sbjct: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1718 Query: 857 RTLPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNN 915 TL S PR RV T +++++W + +++ P G + T P R+ Sbjct: 1719 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1778 Query: 916 VILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPS 975 I LQP T YKI + + ++ + + T + P N+ VSW P Sbjct: 1779 TITG-LQPGTDYKIYLYTLNDNARSSPVVIDASTA-IDAPSNLRFLATTPNSLLVSWQPP 1836 Query: 976 PSPVLGYKIVYKPVGSNEPMEAFVGE---MTSYTLHNLNPSTTYDVNVYAQYDSGLSVPL 1032 + + GY I Y+ GS P E +T T+ L P T Y + V A ++ S PL Sbjct: 1837 RARITGYIIKYEKPGS-PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895 Query: 1033 TDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVR--GSE 1090 + KT Q + W+P + + Y + P GT + + R G+ Sbjct: 1896 ----------IGRKKTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRVPGTS 1944 Query: 1091 TSHCFTGLSPDTDYGVTV 1108 TS TGL+ Y + V Sbjct: 1945 TSATLTGLTRGATYNIIV 1962 Score = 245 bits (625), Expect = 3e-64 Identities = 225/833 (27%), Positives = 358/833 (42%), Gaps = 49/833 (5%) Query: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266 + N V P L P+NL + VSW + + Y++ P +G G E Sbjct: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326 V ++S +L P EY V+VY+V +D+ S P+ T P L ++GP TM Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283 Query: 327 HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384 V W P T +++ Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V Sbjct: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341 Query: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441 S P+ R+ T L P + D+T ++ V W + Y +R+ PE Sbjct: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399 Query: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501 +E V S S +L +L T Y VS+ A++ ESP + Q++T P +L++ Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 502 VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560 T +WD A V YRIT+ G +S E + G ++T L P Y +++ Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 561 TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619 A+ + D S + + I T+ K P +QV + NS++VKW P+S V Y Sbjct: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572 Query: 620 RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679 R+T P G G +T T G Q + ++ L+P Y ++V + P GE + T Sbjct: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-T 1631 Query: 680 LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRN 738 + +L+ + ++L+ +W Y++ P GP + + + +++ ++ Sbjct: 1632 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1691 Query: 739 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPV 797 L T Y V+V + TL R +V + T ++ + W + Sbjct: 1692 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1751 Query: 798 LQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 ++V P +G P + + P + R + L P T Y + L L + +P Sbjct: 1752 TGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1810 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV- 916 T P NLR T NSL V+W + Y I Y P + VP R V Sbjct: 1811 T-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVT 1866 Query: 917 --ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDP 974 + L+P T Y I VIA+ + L G +T E ++ +SW P Sbjct: 1867 EATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-----------GQEALSQTTISWAP 1915 Query: 975 SPSPVLGYKIVYKPVGSN-EPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYD 1025 Y I PVG++ EP++ V G TS TL L TY++ V A D Sbjct: 1916 F-QDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 1967 Score = 202 bits (515), Expect = 2e-51 Identities = 238/984 (24%), Positives = 396/984 (40%), Gaps = 98/984 (9%) Query: 212 CNSVKGPGDLEAPSNLVISERTHR--SFRVSWTPPSDS-VDRYKVEYYPVSG-GKRQEFY 267 C ++ P + I+E + S + W P S + +Y + + P + G+ +E Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEAT 658 Query: 268 VSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKG--TEKTLPVPVVSLNIYDVGPTT 325 + S +K LKP Y + S+ + + E + T + PV S + G TT Sbjct: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTV--TGETT 716 Query: 326 MHVQWQPVGG---------ATGYILSYKPVKDT------------EPTRPKEVRLGPTVN 364 + P+ A+ +++S+ DT E P+ + L T Sbjct: 717 ---PFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773 Query: 365 DMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEP 424 + + DL+P +Y V V + D + T P D + V +++ V W Sbjct: 774 SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSR 833 Query: 425 VPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS--LKDLFSQTLYTVSVSAVHDEGESPPV 482 + Y + Y +P + E++ ET+ S L DL Y +++ AV + ES PV Sbjct: 834 PQAPITGYRIVY-SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV 892 Query: 483 TAQETTR------PVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 536 Q+ T VP+P +L+ EVT W S V+ YR+ P + Sbjct: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ 952 Query: 537 ILNGDENTLV-FENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPK-SGPRN 594 L NT L+P Y + A+ P+ Q K P N Sbjct: 953 RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----------PLTAQQTTKLDAPTN 1002 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654 LQ N T +++ V+W P ++ YR+T T G + +G + L+ L+P + Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061 Query: 655 YTITVSSLYPDGEGGRMTGRGKT-------KPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 707 YT+++ ++ + E + TG T P NT + + +T+ + W A P Sbjct: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-------EVTETTIVITWTPA---P 1111 Query: 708 R-QYKLFYAPAAGG--PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDT 764 R +KL P+ GG P E+ G+ ++ L P Y T+ V +G R + Sbjct: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSI---VVSGLTPGVEYVYTI-QVLRDGQE-RDAPI 1166 Query: 765 GRTLMRGLARNVQVY---NPTPNSLDVRWDPAPGP-VLQYRVVYSPVDGTRPSE-SIVVP 819 ++ L+ ++ NP L V W+ + P + YR+ +P +G + + VV Sbjct: 1167 VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226 Query: 820 GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGETTNSLS 878 + + L P Y+V++ + D E P +P P +LR +++ Sbjct: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--VPISDTIIPAVPPPTDLRFTNIGPDTMR 1284 Query: 879 VAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYED 937 V W + + + YSP + ++ N V+L L P T Y ++V +VYE Sbjct: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1344 Query: 938 GDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG-SNEPME 996 + L G +T GL P I SD F V W + + GY+I + P S P E Sbjct: 1345 HESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1403 Query: 997 AFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDT 1055 V S TL NL P T Y V++ A S L Q +T+ DL+ + Sbjct: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS 1463 Query: 1056 FCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTVFVQTP 1113 + W +P YR+ G QE TV GS+++ +GL P DY +TV+ T Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523 Query: 1114 NLEGPG----VSVKEHTTV-KPTE 1132 + P +S+ T + KP++ Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQ 1547 Score = 200 bits (508), Expect = 1e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 942 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 999 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 155 bits (391), Expect = 5e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 1025 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 1026 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 1082 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 1083 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 278 bits (710), Expect = 5e-74 Identities = 194/651 (29%), Positives = 277/651 (42%), Gaps = 136/651 (20%) Query: 1336 VCETATSSCPLIYLDGY--TSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQK 1393 V + SCP++ ++G+ T LE + S++ ES + +++ Sbjct: 26 VRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLGDSFSLRRAFCESDK----TCFKLG- 80 Query: 1394 NAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSK 1453 +A + + T + P GLP Y++ +FR+ + + +WQ+ ++ PQ+ ++ D K Sbjct: 81 SALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNIPQISIVVDGGKK 140 Query: 1454 TLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEA 1513 + F + T G+V F E++ LF +HK+ I + S+ + +Y+DC I + E Sbjct: 141 VVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMDCNLIARRQTDEK 200 Query: 1514 GNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCP---- 1569 + G ++ + K ++ I CS +++ CC+I + KCP Sbjct: 201 DTVDFHGRTVIA-TRASDGKPVDIELHQLKIYCSANLIAQETCCEI----SDTKCPEQDG 255 Query: 1570 ------------------------AFPNSCTC--TQDSVGPPGPPGPAGGPGAKGPRGER 1603 + C C + G PG PG G G KG GE Sbjct: 256 FGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGEN 315 Query: 1604 GISGAIGPPGPRGDIGPPGPQGPPGPQGPNG----LSIPGEQGRQGMKGDA---GEPGLP 1656 G+ GA G PG +G+ G G +G G +G G ++ G G G+KGD G PG Sbjct: 316 GLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPK 375 Query: 1657 GRTGTPGLPGPP---------GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGV---- 1703 G G G PGPP GP GPPG G G+ G GP G PGPPG PG PG+ Sbjct: 376 GEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIH 435 Query: 1704 ----------------------TGPSGKPGKPGDHGRPGPSGLKGE------KGDRGDIA 1735 G G+ G PG G GP G KGE KG++GD Sbjct: 436 QTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRG 495 Query: 1736 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 1795 ++ + Q + +PG PGPPG GS G +G+ Sbjct: 496 EPGVIGS----------------------------QGVKGEPGDPGPPGLIGSPGLKGQQ 527 Query: 1796 ------GPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGP---PGPQGESR 1846 GP G PG G PG G PG++G+ GEKG+ G G GP GLPGP GP G+S Sbjct: 528 GSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-GIIGPPGLPGPKGEAGPPGKSL 586 Query: 1847 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG G+ G PGP G G G+ G G PG I G G PG Sbjct: 587 PGEPGLDGNPGAPGPRGPKGERGLPGVHGSPG--------DIGPQGIGIPG 629 Score = 214 bits (544), Expect = 8e-55 Identities = 143/358 (39%), Positives = 161/358 (44%), Gaps = 106/358 (29%) Query: 1582 VGPPGPPGPAGGPGAKGPRG------ERGISGAIGPPGP------RGDIGPPGPQGPPGP 1629 +GP GPPGP G G GP G GI G GPPG RG GPPG GPPGP Sbjct: 366 LGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGP 425 Query: 1630 QGPNGL-----SIPG----------EQGRQGMKGDAGEPGLPGRTGT------PGLPGPP 1668 GP G+ ++ G E G+KGD GE GLPG G+ G PG P Sbjct: 426 PGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEP 485 Query: 1669 GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG---SPGVTG------------PSGKPGKP 1713 G GDRG G G+ G +G PG PG PG SPG+ G P G G P Sbjct: 486 FTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLP 545 Query: 1714 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSS 1773 G+HG PG G+KGEKGD G I Sbjct: 546 GEHGIPGKQGIKGEKGDPGGII-------------------------------------- 567 Query: 1774 RNQPGPPGPPGPPGSAGARGE--PGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----- 1826 GPPG PGP G AG G+ PG G G PG PG +GP GERGLPG G G Sbjct: 568 ----GPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQ 623 Query: 1827 -------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 1877 TG+ GP G PG GP+G G PG+ G+ G G PGR G G+ GPPG P Sbjct: 624 GIGIPGRTGAQGPAGEPGIQGPRG--LPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDP 679 Score = 212 bits (539), Expect = 3e-54 Identities = 142/385 (36%), Positives = 163/385 (42%), Gaps = 101/385 (26%) Query: 1582 VGPPGPPGPAG--GPGAKGPRGERGISG---AIGPPGPRGDIGPPGPQGPPGPQGPNGLS 1636 +GPPG PGP G GP K GE G+ G A GP GP+G+ G PG G PG GP G+ Sbjct: 567 IGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIG 626 Query: 1637 IPGEQGRQGMKGDAG------------EPGLPGRTGTPGLPGPPGPMGPPGD-------- 1676 IPG G QG G+ G PG PG G PG G PG GPPGD Sbjct: 627 IPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLG 686 Query: 1677 ------RGFTG-----------------------------KDGAMGPRGPPGPPGS---- 1697 + F G + G +GPRGPPG PG Sbjct: 687 DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPK 746 Query: 1698 -----------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDI 1734 PG PG GP+G PG G G PGP+G KGEKG G Sbjct: 747 GSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPP 806 Query: 1735 ASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE 1794 E+ + + +N +P + PGPPGPPGP G G GE Sbjct: 807 GKPGPPGPPGIPFNERNGMSSLYKIKGGVN-VP-------SYPGPPGPPGPKGDPGPVGE 858 Query: 1795 PGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGST 1853 PG G PG G PG++G G G PG G SG G PGPPG GE GP G Sbjct: 859 PGAMGLPGLEGFPGVKGDRGPAGPPGI-----AGMSGKPGAPGPPGVPGEPGERGPVGDI 913 Query: 1854 GSRGPPGPPGRPGNSGIRGPPGPPG 1878 G GP GP G+PG +G G PG G Sbjct: 914 GFPGPEGPSGKPGINGKDGIPGAQG 938 Score = 211 bits (537), Expect = 5e-54 Identities = 140/367 (38%), Positives = 158/367 (43%), Gaps = 104/367 (28%) Query: 1583 GPPGPPGPAGGPGA----------------------KGPRGERGISGAIGPPGP------ 1614 G PG PGP G P A G + +G G G PG Sbjct: 668 GKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMAR 727 Query: 1615 RGDIGPPGPQGPPGPQGPNGLS-------IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 1667 +GDIGP GP G PG +GP G IPGE+G +G++G G PG PG TG PGL G Sbjct: 728 KGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGR 787 Query: 1668 PGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP-----------------------GSPGVT 1704 G GP G +G G DG G GPPGPPG P G PG Sbjct: 788 TGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPP 847 Query: 1705 GPSGKPG---KPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 1761 GP G PG +PG G PG G G KGDRG Sbjct: 848 GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG-------------------------- 881 Query: 1762 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGPGGRPGFPGTPGMQGPPGE 1815 P +PG PGPPG PG G RG PGP G G PG G G PG Sbjct: 882 -----PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA 936 Query: 1816 RGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPP 1874 +G+ G+ G+RG G G +G+PG G QGE G PG TG +G GP G PGN G G P Sbjct: 937 QGIMGKPGDRGPKGERGDQGIPGDRGSQGER--GKPGLTGMKGAIGPMGPPGNKGSMGSP 994 Query: 1875 ---GPPG 1878 GPPG Sbjct: 995 GHQGPPG 1001 Score = 208 bits (530), Expect = 4e-53 Identities = 147/410 (35%), Positives = 166/410 (40%), Gaps = 118/410 (28%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SI 1637 +GP GPPG G G KG +GERG G G G G G PG G PGP GP GL Sbjct: 731 IGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGH 790 Query: 1638 PGEQGRQGMKGDAGEPGLPGRTGTPGL-----------------------PGPPGPMGPP 1674 PG G +G KG G PG PG G PG+ PGPPGP GP Sbjct: 791 PGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPK 850 Query: 1675 GDRGFTGKDGAM---------------GPRGPPGPPGSPGSPGVTGPSGKPGKP------ 1713 GD G G+ GAM GP GPPG G G PG GP G PG+P Sbjct: 851 GDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPV 910 Query: 1714 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQ-IPND--Y 1770 GD G PGP G G+ G G + + G + +Q IP D Sbjct: 911 GDIGFPGPEGPSGKPGINGKDGIPGAQGIMGK-------PGDRGPKGERGDQGIPGDRGS 963 Query: 1771 QSSRNQP---------GPPGPPGPPGSAGARGEPGPGGRPGFPGTP-------------- 1807 Q R +P GP GPPG GS G+ G GP G PG PG P Sbjct: 964 QGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYIN 1023 Query: 1808 ------------------------------GMQGPPGERGLPGEKGERGTGSSGPRGLPG 1837 G GPPG+ GLPG G+ GP+G G Sbjct: 1024 QEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD-----PGPQGYRG 1078 Query: 1838 PPGPQGESRTGPPGSTGSRGPP--GPPGRPGNSGIRGPPGPPGYCDSSQC 1885 G +GE G PGS G G G PG PG G +GPPGP G C+ C Sbjct: 1079 QKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128 Score = 145 bits (367), Expect = 3e-34 Identities = 100/296 (33%), Positives = 115/296 (38%), Gaps = 100/296 (33%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP---PGPRGDIGPPGPQ- 1624 PA P G PGPPG G PG +GP G+ G G GP PG G G PG Q Sbjct: 879 PAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQG 938 Query: 1625 --GPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK 1682 G PG +GP GE+G QG+ GD G G G+ G G+ G GPMGPPG++G G Sbjct: 939 IMGKPGDRGPK-----GERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS 993 Query: 1683 DGAMGPRGPPGPPGSPGSP----------------------------------------- 1701 G GP G PG PG P Sbjct: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 Query: 1702 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 1761 G GP GK G PG G PGP G +G+KG+RG+ Sbjct: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI------------------------- 1088 Query: 1762 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERG 1817 G PG PG PG++ G PG PG PG QGPPG G Sbjct: 1089 ----------------GLPGSPGLPGTSAL-------GLPGSPGAPGPQGPPGPSG 1121 Score = 85.5 bits (210), Expect = 5e-16 Identities = 56/153 (36%), Positives = 63/153 (41%), Gaps = 49/153 (32%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISG---------------------------------- 1607 +GPPG G G PG +GP G GI G Sbjct: 982 MGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 Query: 1608 ----------AIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPG 1657 A G PGP G G PGP G PGPQG G GE+G G+ G G PGLPG Sbjct: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK--GERGEPGI-GLPGSPGLPG 1098 Query: 1658 RT--GTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 + G PG PG PGP GPPG G + + P Sbjct: 1099 TSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 Score = 56.2 bits (134), Expect = 3e-07 Identities = 32/77 (41%), Positives = 35/77 (45%), Gaps = 10/77 (12%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGI----------SGAIGPPGPRGDIGPPGPQGPPGPQGP 1632 GPPG PGP G G KG RGE GI + A+G PG G GP GP GP G P Sbjct: 1066 GPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 Query: 1633 NGLSIPGEQGRQGMKGD 1649 P Q G+ Sbjct: 1126 EDCLYPVSHAHQRTGGN 1142 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 264 bits (675), Expect = 5e-70 Identities = 154/345 (44%), Positives = 181/345 (52%), Gaps = 47/345 (13%) Query: 1583 GPPGPPGPAGGPGAKGPRGERG---ISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IP 1638 GPPG G G GA GPRGE G + G G PG GD GP GPQGP GP+GP G + P Sbjct: 720 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779 Query: 1639 GEQGRQGMKGDAGEPGLPGRTGTPGLPG---PPGPMGPPGDRGFTGKDGA---------- 1685 G G G G G+ G G G+PGLPG P GP G PG++G GK+G Sbjct: 780 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 839 Query: 1686 --------MGPRGPPGPPGSPGSPGVTG---------PSGKPGKPGDHGRPGPSGLKGEK 1728 G +GPPG G PG PG+ G P G PG+ G G PGP G G Sbjct: 840 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 899 Query: 1729 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-QSSRNQPGPPGPPGP-- 1785 G RG+ S +R R + E+L R +L Q+P Y +SS+ +PGPPGPPG Sbjct: 900 GLRGESPSMETLR---RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 956 Query: 1786 -PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTG---SSGPRGLPGPPGP 1841 PG AG GEPG G+ G G G GP GERG G+ G G G GP G+PG PG Sbjct: 957 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1016 Query: 1842 QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 1886 G ++ G PG G +G GP G PG + GPPGPPG CD SQCA Sbjct: 1017 PGYAKDGLPGIPGPQGETGPAGHPG---LPGPPGPPGQCDPSQCA 1058 Score = 247 bits (630), Expect = 9e-65 Identities = 142/314 (45%), Positives = 164/314 (52%), Gaps = 67/314 (21%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIPGEQ 1641 G PG PG G PG GP G GI+GA GPPG +G PG +GPPGPQGP+GL IPGE+ Sbjct: 633 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGLPGIPGEE 689 Query: 1642 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------PGPP 1695 G++G G G PG PG+ G PGLPGP G GPPG +G TG GA GPRG PG Sbjct: 690 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 749 Query: 1696 GSPGSPGVTGPS------------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 G PG G TGP+ GK G PG G PGPSG G+KG +G+ S + Sbjct: 750 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---- 805 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 1803 PG GP GPPG G +G PG G PG Sbjct: 806 ---------------------------------PGFLGPRGPPGEPGEKGVPGKEGVPGK 832 Query: 1804 PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGP 1858 PG PG + GERG PG KG++G G G G PG PG +G + G PG G GP Sbjct: 833 PGEPGFK---GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 889 Query: 1859 PGPPGRPGNSGIRG 1872 PGPPG+PG G+RG Sbjct: 890 PGPPGQPGFPGLRG 903 Score = 241 bits (616), Expect = 4e-63 Identities = 147/333 (44%), Positives = 164/333 (49%), Gaps = 42/333 (12%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SI 1637 Q G GP GP G PGAKG G G GA G PG G +G PGP GPPG G GL Sbjct: 367 QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGT 426 Query: 1638 PGEQGRQGMKGDAGEPGLPGRT------GTPGLPGPP--GPMGPPGDRGFTGKDGAMGPR 1689 PG+ G +G KG AGE G PG G PGLPGPP G G PG RG G G +G + Sbjct: 427 PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 486 Query: 1690 GPPGPPGSPGSP--------GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--------D 1733 G G PG PGSP GV GP G G PGD G PG GL G G +G Sbjct: 487 GDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSS 546 Query: 1734 IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARG 1793 + S + +A+ VC G L +P + G PG PG G+ G +G Sbjct: 547 LLSPGDINLLAKDVCNDCPPGPPG-----LPGLP----GFKGDKGVPGKPGREGTEGKKG 597 Query: 1794 EPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGPPGPQG-ES 1845 E GP G PG PG G QG GERG GE G++G G GP G PGPPG G Sbjct: 598 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 657 Query: 1846 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GPPG GS G GPPG G SG+ G PG G Sbjct: 658 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 690 Score = 228 bits (580), Expect = 6e-59 Identities = 142/356 (39%), Positives = 161/356 (45%), Gaps = 52/356 (14%) Query: 1560 PSRRDEGKCPAFPN--SCTCTQDSVGPPGPPGPAGGPGA------KGPRGERGISGAIGP 1611 P R E P P Q G PG G AG PGA +G +G++G G +G Sbjct: 252 PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 311 Query: 1612 PGPRGDIGPPGPQGPPGPQGPNGLS--------IPGEQGRQGMKGDAGEPGLPGRTGTPG 1663 PG +GD G G GP GP G G + +PGEQG +G KGD G PG PG G PG Sbjct: 312 PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 371 Query: 1664 LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG 1723 GP GP GPPG +G G GA G G PG PG G+PG +GP G G PG G PG G Sbjct: 372 ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 431 Query: 1724 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 1783 +GEKG G+ S + R PG PG P Sbjct: 432 ERGEKGAAGEEGSPGPV-------------------------------GPRGDPGAPGLP 460 Query: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 1843 GPPG G GEPG G PG PG G +G G G+PG G RG G G PGP GP G Sbjct: 461 GPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 519 Query: 1844 ESRTGPPGSTGSRGPPGPPGRPGNSGIRG--PPGPPGYCDSSQCASIPYNGQGYPG 1897 + G PGS G G PGP G G G+ PG C P G PG Sbjct: 520 DK--GSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG 573 Score = 228 bits (580), Expect = 6e-59 Identities = 162/401 (40%), Positives = 184/401 (45%), Gaps = 89/401 (22%) Query: 1583 GPPGPPGPAGGPGAKGP------RGERGISG---AIGPPGPRGDIGPPGPQGPP--GPQG 1631 GP GPPG G PG +G RGE+G +G + GP GPRGD G PG GPP G G Sbjct: 410 GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 469 Query: 1632 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLP-----GPPGPMGPPGD------RGF 1679 GL PG G G KGD G PG+PG G+ G P GPPGP GPPGD RG Sbjct: 470 EPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 529 Query: 1680 TGKDGAMGPRG------------------------PPGPPGSPGSPGVTGPSGKPGKPGD 1715 G G GP G PPGPPG PG PG G G PGKPG Sbjct: 530 PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 589 Query: 1716 HGR------------PGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQM----NRF 1759 G PGP G+ G +G +G+ + + Q + G M N Sbjct: 590 EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ-GHPGVPGFMGPPGNPG 648 Query: 1760 NQMLNQI-----PNDYQSSRNQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPG 1805 + I P Q S + GPPGP GP G G GE PGP G PG G Sbjct: 649 PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG 708 Query: 1806 TPGMQGPPGERGLPGEKGERG-TGSSGPR------GLPGPPG-PQGESRTGPPGSTGSRG 1857 PG+ GP G RG PG KG G +G+ GPR GLPG G P + TGP G G +G Sbjct: 709 EPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 768 Query: 1858 PPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ-GYPG 1897 P GPPG+ G+ G G PGP G Q S NG G PG Sbjct: 769 PRGPPGKNGSPGSPGEPGPSG--TPGQKGSKGENGSPGLPG 807 Score = 224 bits (572), Expect = 5e-58 Identities = 152/389 (39%), Positives = 185/389 (47%), Gaps = 76/389 (19%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS------ 1636 G G PG G PG +G +G++G G +G PG +GD G G GP GP G G + Sbjct: 283 GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH 342 Query: 1637 --IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA--------- 1685 +PGEQG +G KGD G PG PG G PG GP GP GPPG +G G GA Sbjct: 343 PRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA 402 Query: 1686 ---MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRA 1742 +G GP GPPGS G+PG+ G GK G+ G+ G G G G G RGD + + Sbjct: 403 PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP 462 Query: 1743 VAR-QVCEQLISGQM-------NRFNQMLNQIPNDYQSSRNQP-----GPPGPPGPP--- 1786 + + E + G + ++ IP SR P GPPGP GPP Sbjct: 463 PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGS-PGSRGDPGIGVAGPPGPSGPPGDK 521 Query: 1787 GSAGARGEP------GPGGR------------------------PGFPGTPGMQGPPGER 1816 GS G+RG P GP GR PG PG PG+ G G++ Sbjct: 522 GSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581 Query: 1817 GLPGEKGERGT----GSSGPRGLPGPP---GPQG-ESRTGPPGSTGSRGPPGPPGRPGNS 1868 G+PG+ G GT G +GP GLPGPP GPQG + G G G +G G PG PG Sbjct: 582 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641 Query: 1869 GIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G G PGPPG D A+ P QG PG Sbjct: 642 GPPGNPGPPG-ADGIAGAAGPPGIQGSPG 669 Score = 176 bits (447), Expect = 1e-43 Identities = 126/332 (37%), Positives = 148/332 (44%), Gaps = 53/332 (15%) Query: 1595 GAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPG 1654 G +GP +R + A + G G PG +G +GL G+ G++G+ GE G Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLP-----GKPGLRGEIGEQG 274 Query: 1655 LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG 1714 L GR G G G PG G PG RG G G G G PG G G G GP+G PG PG Sbjct: 275 LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 334 Query: 1715 ------DHGR-PGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 1767 H R PG G KGEKGD G E + G+ P Sbjct: 335 TTSLFTPHPRMPGEQGPKGEKGDPG-------------LPGEPGLQGRPGELGPQGPTGP 381 Query: 1768 NDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG- 1826 + G PG G PG+ G G PGP G PG G PG++G PG+ G GEKG G Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 441 Query: 1827 ---TGSSGPR---GLPGPPGPQGESRTGPPGSTGSRGPPGP---------PGRPGNSGIR 1871 G GPR G PG PGP G+ + G PG GS G PGP PG PG+ G R Sbjct: 442 EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSR 501 Query: 1872 GPP-----GPPGYCDSSQCASIPYNGQGYPGS 1898 G P GPPG S P +G PGS Sbjct: 502 GDPGIGVAGPPG-------PSGPPGDKGSPGS 526 Score = 108 bits (269), Expect = 6e-23 Identities = 59/128 (46%), Positives = 67/128 (52%), Gaps = 13/128 (10%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 PA+ S +Q GPPGPPG G PG GP GE G G G GP G IGP G +G G Sbjct: 936 PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 992 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 G G+ + GE G G+ G GEPG + G PG+PGP G GP G G Sbjct: 993 DPGAPGVGLRGEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGPAGHPGLP-------- 1043 Query: 1689 RGPPGPPG 1696 GPPGPPG Sbjct: 1044 -GPPGPPG 1050 Score = 101 bits (252), Expect = 6e-21 Identities = 89/275 (32%), Positives = 105/275 (38%), Gaps = 79/275 (28%) Query: 1649 DAGEPGLPGRTGTPGLPGPPGPMG--PPGDRGFTGKD--GAMGPRGPPGPPG-------- 1696 D G G GR T LP P P G TG + A+G +GP Sbjct: 182 DQGAQGACGRGNTSVLPSSVAPQCSMPKG----TGHEFSAALGTQGPADQRADARASCIL 237 Query: 1697 -SPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQ 1755 + +PG+ +G+PG+ G+ G PG GL RG+I Sbjct: 238 AAKTAPGLKQLNGEPGERGEDGLPGKPGL------RGEI--------------------- 270 Query: 1756 MNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE 1815 G G G PG G G PG G PG G G QG GE Sbjct: 271 ----------------------GEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE 308 Query: 1816 RGLPGEKGERGT-GSSGPRGLPGPPG--------PQGESRTGPPGSTGSRGPPGPPG--- 1863 GLPG KG+RG G +GP G PG PG P+ GP G G G PG PG Sbjct: 309 LGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 368 Query: 1864 RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 RPG G +GP GPPG P G PG+ Sbjct: 369 RPGELGPQGPTGPPGAKGQEGAHGAP-GAAGNPGA 402 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 259 bits (663), Expect = 1e-68 Identities = 147/341 (43%), Positives = 177/341 (51%), Gaps = 34/341 (9%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G PGPPG G PGA+G E G G G PGP G +GPPGP G PGP G + + + G++G Sbjct: 1261 GKPGPPGSTGRPGAEG---EPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRG 1317 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPP------------------GPMGPPGDRGFTGKDG 1684 G +G AG PG PG G PG PG P GP GP GD G G+ G Sbjct: 1318 ATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKG 1377 Query: 1685 AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGR---PGPS---GLKGEKGDRGDIASQN 1738 G +G G PG PG G GP G PG G+ G PGPS GL G G GD+ + + Sbjct: 1378 QAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYD 1437 Query: 1739 MMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 1798 ++ RQ ++ +M + + Q P + ++ +PGPPG G PG GA G P Sbjct: 1438 EIKRFIRQEIIKMFDERMAYYTSRM-QFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP--- 1493 Query: 1799 GRPGFPGTPGMQGPPGERGLPGEKGER---GTGSSGPRGLPGPPGPQGESRTGPPGSTGS 1855 G PG G G QG PG RGLPG KGE+ G G +G GLPGPPGPQG G G+TG Sbjct: 1494 GLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGP 1553 Query: 1856 RGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP 1896 G G PG PG G G PG G+C+ S C Q YP Sbjct: 1554 MGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYP 1594 Score = 243 bits (619), Expect = 2e-63 Identities = 144/321 (44%), Positives = 163/321 (50%), Gaps = 49/321 (15%) Query: 1559 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 1618 +P +R E P S +GPPG PG G PG G +GERG++G G +G+ Sbjct: 1028 LPGQRGEEGPPGMRGS-PGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGL---TGDKGEP 1083 Query: 1619 GPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRG 1678 GPPG G PG GP GL PG +G +G G AGE G PG G+ GLPGPPGP GP G+RG Sbjct: 1084 GPPGQPGYPGATGPPGL--PGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERG 1141 Query: 1679 FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQN 1738 G G G +G G PG PG P GP G PGK G G PGP KG +G RG Sbjct: 1142 PQGNSGEKGDQGFQGQPGFPGPP---GPPGFPGKVGSPGPPGPQAEKGSEGIRG------ 1192 Query: 1739 MMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 1798 P+ S PGPPGPPG G AG G G Sbjct: 1193 ----------------------------PSGLPGS---PGPPGPPGIQGPAGLDGLDGKD 1221 Query: 1799 GRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRG 1857 G+PG G PG GPPG G PG KG+ G G GP+G G PGP G TG PG+ G G Sbjct: 1222 GKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGS--TGRPGAEGEPG 1279 Query: 1858 PPGPPGRPGNSGIRGPPGPPG 1878 GP GRPG G GPPGPPG Sbjct: 1280 AMGPQGRPGPPGHVGPPGPPG 1300 Score = 237 bits (605), Expect = 7e-62 Identities = 142/329 (43%), Positives = 158/329 (48%), Gaps = 74/329 (22%) Query: 1583 GPPGPPGPAGGPGAKGP------RGERGISGAIGP---PGPRGDIGPPGPQGPPGPQGPN 1633 G PGPPG G PGA GP +GERG +G+ G PGP G G PGP GP GP+G Sbjct: 1081 GEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGER 1140 Query: 1634 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 1693 G G G +G +G G+PG PG G PG PG G GPPG + G +G GP G PG Sbjct: 1141 GPQ--GNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPG 1198 Query: 1694 PPGSPGSPGVTGPS------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQV 1747 PG PG PG+ GP+ GK GKPG G PGP+G G G Sbjct: 1199 SPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMG------------------ 1240 Query: 1748 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGPPGSA---GARGEPGPG 1798 P ++ PG PGP PGPPGS GA GEPG Sbjct: 1241 -------------------PPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAM 1281 Query: 1799 GRPGFPGTPGMQGPPGERGLPGE--------KGERG-TGSSGPRGLPGPPGPQGESRTGP 1849 G G PG PG GPPG G PG KG+RG TG G GLPG PGP G GP Sbjct: 1282 GPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG--HPGP 1339 Query: 1850 PGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 PG G+ G G G PG G GPPGP G Sbjct: 1340 PGEPGTDGAAGKEGPPGKQGFYGPPGPKG 1368 Score = 231 bits (590), Expect = 4e-60 Identities = 143/341 (41%), Positives = 165/341 (48%), Gaps = 76/341 (22%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGE---------RGISGAIGPPGPRGDIGPPGPQGPPGPQ- 1630 S G PGPPGPAG G +GP+G +G G GPPGP G G G GPPGPQ Sbjct: 1124 SEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQA 1183 Query: 1631 --------GPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP------MGPPG 1675 GP+GL PG G G++G AG GL G+ G PGL G PGP MGPPG Sbjct: 1184 EKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPG 1243 Query: 1676 DRGFTGKDGAMGPRGPPGPPGSPGS---------PGVTGPSGKPGKPGDHGRPGPSGLKG 1726 +G TG G GP+G G PG PGS PG GP G+PG PG G PGP G G Sbjct: 1244 FKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPG 1303 Query: 1727 E--------KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPG 1778 KGDRG + + + GQ PG Sbjct: 1304 PAGISAVGLKGDRGATGERGLAG----------LPGQ------------------PGPPG 1335 Query: 1779 PPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGP 1838 PGPPG PG+ GA G+ GP G+ GF G PG +G PG G G+ GE+G G+PG Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRA-----GMPGG 1390 Query: 1839 PGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 PG G GPPG G RG PG PG G+ G+ G PG G Sbjct: 1391 PGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMG 1431 Score = 226 bits (577), Expect = 1e-58 Identities = 186/620 (30%), Positives = 246/620 (39%), Gaps = 174/620 (28%) Query: 1397 VNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLS 1456 V QPT + P GLP + ++L L T + ++Q+TD + PQ+ + + ++L Sbjct: 84 VTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLE 143 Query: 1457 FFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNI 1516 + G+ + F V LF +HK+ + V + +++DC + + + Sbjct: 144 LRAQGQDGDFVSCIF---PVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPM 200 Query: 1517 TTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDI----------PSRRD-- 1564 G+ LG L + K +F +Q I C P + CC+I +RRD Sbjct: 201 RPVGHVFLG-LDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDTQ 259 Query: 1565 -----------EGK------CPAFPNSCTCTQDSVG---------------------PP- 1585 EGK C P + G PP Sbjct: 260 SNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPC 319 Query: 1586 -----------GPPGPAGG------PGAKGPRGERGISG----AIGPPGP-RGDIGPPGP 1623 P GP GG PG G +GE+G G I P P + GP G Sbjct: 320 VHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGE 379 Query: 1624 QGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP---PGPMGPPGDRGF 1679 +G G GP+GL GE+G++G KGD G G+PG+ G G PG GP G GD GF Sbjct: 380 KGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGF 439 Query: 1680 TGKDGAMGPRGPPG---------------PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 1724 G +G G GPPG P G PG G G SG PGK G G+PG G+ Sbjct: 440 VGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGV 499 Query: 1725 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 1784 KGEKGD +VC L P +Q+ PG PGP G Sbjct: 500 KGEKGD-------------PCEVCPTL---------------PEGFQNFVGLPGKPGPKG 531 Query: 1785 PPGS-AGARGEPGPGGRPGFPGTP----------------------------GMQGPPGE 1815 PG ARG+PG G G G P G+ G PG Sbjct: 532 EPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGR 591 Query: 1816 RGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPP------------ 1862 G+PG KGE+G G +GP G PGPPGP GP G G++G P P Sbjct: 592 AGVPGLKGEKGNFGEAGPAGSPGPPGP-----VGPAGIKGAKGEPCEPCPALSNLQDGDV 646 Query: 1863 ---GRPGNSGIRGPPGPPGY 1879 PG SG +G PGPPG+ Sbjct: 647 RVVALPGPSGEKGEPGPPGF 666 Score = 223 bits (568), Expect = 1e-57 Identities = 152/410 (37%), Positives = 187/410 (45%), Gaps = 92/410 (22%) Query: 1580 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRGDIGP---------PGPQG 1625 + VG PG PG G PG +GP G +G+ G GPP GP+G+ G PGP+G Sbjct: 753 EGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG 812 Query: 1626 PPGPQ------------------GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 1667 PPGP GP G S+ G GR G +G G G PG G G G Sbjct: 813 PPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGE 872 Query: 1668 PGPMGPP--GDRGFTGKDGAMGP-RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 1724 PG P GD F+G GA G G PG G PG+ GP G PG PG G PG +GL Sbjct: 873 PGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGL 932 Query: 1725 KGEKGDRGDIASQNMMRAVARQVCEQLISGQM----------NRFNQMLNQIPN------ 1768 G+ G ++ S + + + + +C + GQ + +Q + +P Sbjct: 933 PGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ 992 Query: 1769 -------------DYQSSRNQP---GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP 1812 +S P G PG PGPPG G RGE GP G G PG PG GP Sbjct: 993 CFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGP 1052 Query: 1813 P------GERGLPGEKGERG-TGSSGPRGLPGPPGPQG-ESRTGPP---------GSTGS 1855 P G GLPG +GERG TG +G +G PGPPG G TGPP G TGS Sbjct: 1053 PGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGS 1112 Query: 1856 RGPPGPPGRPGNSGIRGPPGPPG-------YCDSSQCASIPYNGQ-GYPG 1897 G G PG PG+ G+ GPPGP G +S + + GQ G+PG Sbjct: 1113 AGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPG 1162 Score = 208 bits (529), Expect = 5e-53 Identities = 135/350 (38%), Positives = 169/350 (48%), Gaps = 51/350 (14%) Query: 1583 GPPGPPG-----PAGGPGAKGPRGERGISGAIGPPGPRGDIGP---PGPQGPPGPQGPNG 1634 G PGPPG P G PGA G G +G+ G GPPGP G+ G PG +G GP GP G Sbjct: 780 GEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG 839 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--GDRGFTGKDGAMGP-RGP 1691 S+ G GR G +G G G PG G G G PG P GD F+G GA G G Sbjct: 840 ASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGS 899 Query: 1692 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 1751 PG G PG+ GP G PG PG G PG +GL G+ G ++ S + + + + +C Sbjct: 900 SWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDC 959 Query: 1752 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG------------PPGSAGARGEPGPGG 1799 + GQ ++ + + G PG PG P + ARG+ G Sbjct: 960 VQGQRAHPGYLVEK------GEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGD 1013 Query: 1800 RPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPP 1859 PG G+PG+ GPPG LPG++GE G G RG PGPPGP GPPG G+ G P Sbjct: 1014 -PGCVGSPGLPGPPG---LPGQRGEEGP--PGMRGSPGPPGP-----IGPPGFPGAVGSP 1062 Query: 1860 GPPGRPGNSGIRG---------PPGPPGYCDSSQCASIP--YNGQGYPGS 1898 G PG G G+ G PPG PGY ++ +P +GY GS Sbjct: 1063 GLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGS 1112 Score = 207 bits (528), Expect = 6e-53 Identities = 138/383 (36%), Positives = 163/383 (42%), Gaps = 119/383 (31%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP---------------------- 1620 G PG PG AG PG KG +G G +G G PGP G +GP Sbjct: 584 GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643 Query: 1621 --------PGPQGPPGPQGPNGLSIPGEQGR------QGMKGDA---GEPGLPGRTGTPG 1663 PGP G G GP G +PG+QG+ +G KGDA G+PG PG TG PG Sbjct: 644 GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703 Query: 1664 LPGPPGPMGPPGDRG------------------FTGKDGAMGPRGPPGP-----PGSPGS 1700 L G PG GP G +G G+ G GP+G GP PG PG Sbjct: 704 LSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQ 763 Query: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 1760 PG+ G G PG G G PGP G +G +G +G+ + + Sbjct: 764 PGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGL--------------------- 801 Query: 1761 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG--MQGPPGERGL 1818 + PGP GPPGP G GA+G PG G G G PG + GPPG G Sbjct: 802 ----------PGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQ 851 Query: 1819 PGEKGERGT-GSSGPRGLPGPPG-----PQGES-----------------RTGPPGSTGS 1855 G+ G RGT G GPRG G PG QG+ + GP G G Sbjct: 852 QGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911 Query: 1856 RGPPGPPGRPGNSGIRGPPGPPG 1878 GPPGPPG PG G+ G G PG Sbjct: 912 PGPPGPPGVPGLQGVPGNNGLPG 934 Score = 207 bits (526), Expect = 1e-52 Identities = 142/391 (36%), Positives = 171/391 (43%), Gaps = 97/391 (24%) Query: 1578 TQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI----GPPGPQGPPGPQGPN 1633 T + G PG G G G GP+GE+G G P +G + G PG GP G QGP Sbjct: 695 TPGTTGRPGLSGEPGVQGPAGPKGEKG-DGCTACPSLQGTVTDMAGRPGQPGPKGEQGPE 753 Query: 1634 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP--GPPGPMGPPGDRGFTGKDGAMGPRGP 1691 G+ PG+ G+ G+ G G PGL G G PG P G GP G PG G G G GPRGP Sbjct: 754 GVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGP 813 Query: 1692 PGP------PGSPGSPGVTGP--------SGKPGKPGDHGRPGPSGLKGEKGDRGDIASQ 1737 PGP GSPG G TGP SG PG+ G G+ G G GEKG RG+ Sbjct: 814 PGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEP 873 Query: 1738 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 1797 ++ + + SG + P + S QPGP GPPG P G PGP Sbjct: 874 GECSCPSQG--DLIFSG--------MPGAPGLWMGSSWQPGPQGPPGIP------GPPGP 917 Query: 1798 GGRPGFPGTPGMQGPPGERGLPGE-------------------KGERG-------TGSSG 1831 G PG G PG G PG+ GL E +G+R G G Sbjct: 918 PGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKG 977 Query: 1832 PRGLPGPPG------------------PQGESRTGPPGSTGSRGPPGPPGRPGN------ 1867 +G+PG PG +G++ G PG GS G PGPPG PG Sbjct: 978 DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037 Query: 1868 SGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 G+RG PGPPG P G+PG+ Sbjct: 1038 PGMRGSPGPPG----------PIGPPGFPGA 1058 Score = 147 bits (371), Expect = 1e-34 Identities = 104/285 (36%), Positives = 115/285 (40%), Gaps = 106/285 (37%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 1638 Q GPPGP G G G KG GE+G +G G PG G +GP GP GP Sbjct: 1358 QGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGP------------ 1405 Query: 1639 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG-------------------------- 1672 G+ G PG PG +G+PGLPG PG MG Sbjct: 1406 --------AGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAY 1457 Query: 1673 -------------PPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP 1719 PG G GKDGA G PG PGSPG PG G G+ G PG G P Sbjct: 1458 YTSRMQFPMEMAAAPGRPGPPGKDGA---PGRPGAPGSPGLPGQIGREGRQGLPGVRGLP 1514 Query: 1720 GPSGLKGEKGDRG-DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPG 1778 G KGEKGD G IA +N + PG Sbjct: 1515 ---GTKGEKGDIGIGIAGENGL------------------------------------PG 1535 Query: 1779 PPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKG 1823 PPGP GPPG G G GP G+ G PG P GPPG G PG+ G Sbjct: 1536 PPGPQGPPG-YGKMGATGPMGQQGIPGIP---GPPGPMGQPGKAG 1576 Score = 85.5 bits (210), Expect = 5e-16 Identities = 57/135 (42%), Positives = 61/135 (45%), Gaps = 22/135 (16%) Query: 1571 FPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ 1630 FP GPPG G G PGA G PG G IG G QG PG + Sbjct: 1464 FPMEMAAAPGRPGPPGKDGAPGRPGAP------------GSPGLPGQIGREGRQGLPGVR 1511 Query: 1631 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 1690 G +PG +G KGD G G+ G G PG PGP GP G G G TG G G G Sbjct: 1512 G-----LPGTKGE---KGDIG-IGIAGENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPG 1561 Query: 1691 PPGPPGSPGSPGVTG 1705 PGPPG G PG G Sbjct: 1562 IPGPPGPMGQPGKAG 1576 Score = 72.0 bits (175), Expect = 5e-12 Identities = 53/149 (35%), Positives = 66/149 (44%), Gaps = 21/149 (14%) Query: 1764 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP---- 1819 ++ P +R+ P GP G G RG PGP PG G G +G R P Sbjct: 314 DECPPCVHGARDSNVTLAPSGPKGGKGERGLPGP---PGSKGEKGARGNDCVRISPDAPL 370 Query: 1820 ----GEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGI---- 1870 G KGE+G +G+ GP GLPG G +G+ G G G +G PG PGR G G Sbjct: 371 QCAEGPKGEKGESGALGPSGLPGSTGEKGQK--GEKGDGGIKGVPGKPGRDGRPGEICVI 428 Query: 1871 --RGPPGPPGYCDSSQCASIPYNGQGYPG 1897 +G G PG+ A P G PG Sbjct: 429 GPKGQKGDPGFVGPEGLAGEP-GPPGLPG 456 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 259 bits (662), Expect = 2e-68 Identities = 155/346 (44%), Positives = 175/346 (50%), Gaps = 40/346 (11%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--- 1625 P P T GPPGPPG G PG G RGE G G GPPGP G +GP GP G Sbjct: 950 PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009 Query: 1626 ---------PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 1676 PPGP G GL PG G++G KGD G GLPG+ G PGL G PG G PG Sbjct: 1010 PMGERGHPGPPGPPGEQGL--PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1067 Query: 1677 RGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLK---GEKGD 1730 G G G GP GPPGP GSPG G GP G PG+PG G PGP+G K GEKG Sbjct: 1068 VGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP 1127 Query: 1731 RGDIASQNMMRAV-----ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP 1785 +G + V A V G + + + + PGP GP GP Sbjct: 1128 QGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP 1187 Query: 1786 ---PGSAGARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGP 1832 PG +GA GEPGP G+ G G PG GP G +GLPG GE+G TG G Sbjct: 1188 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247 Query: 1833 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G PGPPGP+G S G PG+ G +GPPG G PG G +G PG G Sbjct: 1248 MGPPGPPGPRGPS--GAPGADGPQGPPGGIGNPGAVGEKGEPGEAG 1291 Score = 256 bits (653), Expect = 2e-67 Identities = 156/377 (41%), Positives = 174/377 (46%), Gaps = 92/377 (24%) Query: 1567 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 1626 K P P Q VG PGP GP G PG G +GE G G G G +G+ GPPGP GP Sbjct: 1125 KGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP 1184 Query: 1627 ------PGPQGPNGLSIP-GEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGP------ 1670 PGP G +G P G+QG G KGD G PG PG G GLPGPPG Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244 Query: 1671 ---MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 1727 MGPPG G G GA G GP GPPG G+PG G G+PG+ G+ G PG G G Sbjct: 1245 VGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGP 1304 Query: 1728 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 1787 KG+RG+ A GPPGP GPPG Sbjct: 1305 KGERGEKGESGPSGAA----------------------------------GPPGPKGPPG 1330 Query: 1788 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG 1843 G +G PGP G PG PG PG GP G+ G PG+KG+ G TGS GP G PGP GP G Sbjct: 1331 DDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390 Query: 1844 E----------------------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCD 1881 + GPPG TG GP G PG+PG G+RG PGP G Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVG--- 1447 Query: 1882 SSQCASIPYNGQGYPGS 1898 QG PGS Sbjct: 1448 ----------EQGLPGS 1454 Score = 255 bits (651), Expect = 3e-67 Identities = 155/352 (44%), Positives = 173/352 (49%), Gaps = 59/352 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP-NGLSIPGEQ 1641 GPPGP G G PG G +GE G G +GPPGP G GP G G GPQGP G+ PG Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281 Query: 1642 GRQGMKGDAGEPGLPGRTGTPG---------------LPGPPGPMGPPGDRGFTGKDGAM 1686 G +G G+AGEPGLPG G PG GPPGP GPPGD G G G + Sbjct: 1282 GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341 Query: 1687 GPRGPPGPPGSPG---------------------SPGVTG---PSGKPGKPGDHGRPGPS 1722 G G PGPPG PG SPG TG PSG PGK G G GP Sbjct: 1342 GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPE 1401 Query: 1723 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 1782 G +GEKG +G+ + + Q G+ P Q PGP GP Sbjct: 1402 GRQGEKGAKGEAGLEGPPGKTG-PIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460 Query: 1783 PGP---PGSAGARGEPGPGGRPGFPGTPGMQGPPGE------RGLPGEKGERG------- 1826 PGP PG G +G+ GP G G PG G+ GPPGE RGLPG +G G Sbjct: 1461 PGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGI 1520 Query: 1827 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 TG SGP G PGPPG G GP G+ GS GP GP G G+ G GPPGPPG Sbjct: 1521 TGPSGPIGPPGPPGLPGPP--GPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 254 bits (648), Expect = 7e-67 Identities = 148/330 (44%), Positives = 168/330 (50%), Gaps = 57/330 (17%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGD------IGPPG 1622 P FP + + G PG PGP G G GPRGERG G G PGP+G+ GPPG Sbjct: 888 PGFPGA-NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPG 946 Query: 1623 PQGPPGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 1681 +GP GPQGP G P G G G G G PG G TG G GPPGP G G +G TG Sbjct: 947 ERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTG 1006 Query: 1682 KDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD------HGRPGPSGLKGEKGDRGDIA 1735 + G MG RG PGPPG PG G+ G +GK G GD G+ GP GL+G GDRG Sbjct: 1007 ETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRG--- 1063 Query: 1736 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 1795 + G + N+ GPPGPPGP GS G RG Sbjct: 1064 ----------------LPGPVGALGLKGNE------------GPPGPPGPAGSPGERGPA 1095 Query: 1796 GPGGRPGFPGTPGMQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTG 1848 G G G PG PG QGPP GE+G PGEKG +G G GP GLPGP GP G Sbjct: 1096 GAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP-----VG 1150 Query: 1849 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 PPG G +G G PG+ G+ G +G GPPG Sbjct: 1151 PPGEDGDKGEIGEPGQKGSKGDKGEQGPPG 1180 Score = 251 bits (641), Expect = 5e-66 Identities = 150/347 (43%), Positives = 167/347 (48%), Gaps = 36/347 (10%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G PGPPGP G G GP GE+G +G +G GP G GP GP G PG GP G PG G Sbjct: 1219 GFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGGIG 1276 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 1702 G G+ GEPG G G PG GPPGP G G++G +G GA GP GP GPPG G G Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336 Query: 1703 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 1762 GP G PG PG G PGP+G G GD+GD + E SG + Sbjct: 1337 SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG-PTGEPGPSGPPGKRGPP 1395 Query: 1763 LNQIPNDYQSSRNQP---------------GPPGPPGPPGSAGARGEPGPGGRPGFPGTP 1807 P Q + GP G PG PG G RG PGP G G PG+P Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP 1455 Query: 1808 GMQGPPGER---GLPGEKGERG----TGSSGPRGLPGPPGPQGE----------SRTGPP 1850 G GPPG GLPG KG+ G G G GL GPPG QGE +GP Sbjct: 1456 GPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK 1515 Query: 1851 GSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G G GP GP G PG G+ GPPGP G SS P G+PG Sbjct: 1516 GEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG-PKGEAGHPG 1561 Score = 242 bits (618), Expect = 2e-63 Identities = 148/348 (42%), Positives = 173/348 (49%), Gaps = 50/348 (14%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGA---IGPPGPRGDIGPPGPQGPPGPQGPNGLS--- 1636 GP GP G G PG GP G G+ G +GP GPRG GPPGP G PG +G G Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618 Query: 1637 -IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------ 1689 +PG+ G +G +G G GLPG G G PGP GP GPPGD G G DG +GPR Sbjct: 619 GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678 Query: 1690 ------GPPGPPGSPGSPGVTGPSGKPGKPGD---HGRPGPSGLKGEKGDRGDIASQNMM 1740 GP GPPG PG PGVTG G+PG G+ G PGP G +G G +G Q + Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAI 738 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR 1800 + G + + L +P + PG PG GPPG G +G PGP G Sbjct: 739 GPPGEK-------GPLGK--PGLPGMP----GADGPPGHPGKEGPPGEKGGQGPPGPQGP 785 Query: 1801 PGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SRTGP 1849 G+PG G++G G RGL G KGE+G G G RG GPPGP+GE GP Sbjct: 786 IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP 845 Query: 1850 PGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G G G PGP G PG G G PG PGY P G+PG Sbjct: 846 KGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG----PKGSIGFPG 889 Score = 239 bits (611), Expect = 1e-62 Identities = 137/315 (43%), Positives = 158/315 (50%), Gaps = 46/315 (14%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNGLSIPGE 1640 +GP GPPGP G P G++G G PGP+G++GP G GPPG QG P +PG Sbjct: 684 LGPKGPPGPPGPP---------GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGP 734 Query: 1641 QGR---QGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGS 1697 QG G KG G+PGLPG G G PG PG GPPG++G G G GP G PGP G Sbjct: 735 QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794 Query: 1698 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 1757 G+ G+ G G G+ G+ G PG G G KGDRG+I G Sbjct: 795 KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEI-------------------GPPG 835 Query: 1758 RFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------GPGGRPGFPGTPGMQG 1811 + + P PGP GPPG G G G P GP G GFPG PG G Sbjct: 836 PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895 Query: 1812 PPGERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPG 1863 G RG PG+ G RG G GPRG+ G PGP+G S GP G G RGP GP G Sbjct: 896 EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQG 955 Query: 1864 RPGNSGIRGPPGPPG 1878 G G +GPPGPPG Sbjct: 956 PTGFPGPKGPPGPPG 970 Score = 239 bits (610), Expect = 2e-62 Identities = 141/328 (42%), Positives = 165/328 (50%), Gaps = 32/328 (9%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP------------PGPQGPPGPQ 1630 G G G G PG KG G +G G IGPPGPRG+ GP PGP GPPG + Sbjct: 805 GTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK 864 Query: 1631 GPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 1689 G G+ +PG GRQG KG G PG PG G G G PG GP G RG TG G GPR Sbjct: 865 GKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPR 924 Query: 1690 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR--QV 1747 G G PG G+ G GP+G PG+ G +G GP+G G KG G + + + Sbjct: 925 GITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984 Query: 1748 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP---------GSAGARGEPGPG 1798 Q +G + Q P + G PGPPGPP G G +G+PGP Sbjct: 985 GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044 Query: 1799 GRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE----SRTGP---P 1850 G PG G PG++G PG+RGLPG G G G+ GP G PGP G GE GP P Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104 Query: 1851 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G G +GPPGP G G G +GP GP G Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAG 1132 Score = 235 bits (600), Expect = 3e-61 Identities = 147/362 (40%), Positives = 167/362 (46%), Gaps = 74/362 (20%) Query: 1579 QDSVGPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 1635 Q ++GPPG GP G PG G G G G GPPG +G GPPGPQGP G GP G+ Sbjct: 735 QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794 Query: 1636 -------------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP--------- 1667 PG +G G+KGD GE G PG G G GP Sbjct: 795 KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854 Query: 1668 PGPMGPPGDR------GFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 1721 PGP+GPPG++ G G G GP+G G PG PG+ G G G PGKPG G+ GP Sbjct: 855 PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914 Query: 1722 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPG 1781 +G +GE+G RG + + + SG + PN Q PGP G Sbjct: 915 TGPRGERGPRG----------ITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKG 964 Query: 1782 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGP 1841 PPGPPG G G PG G GF G G GPPG G G GE TG G RG PGPPGP Sbjct: 965 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE--TGPMGERGHPGPPGP 1022 Query: 1842 QGE----------------------SRTGPP---GSTGSRGPPGPPGRPGNSGIRGPPGP 1876 GE + GPP G G RG PGP G G G GPPGP Sbjct: 1023 PGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP 1082 Query: 1877 PG 1878 PG Sbjct: 1083 PG 1084 Score = 233 bits (594), Expect = 1e-60 Identities = 151/354 (42%), Positives = 167/354 (47%), Gaps = 62/354 (17%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISG---AIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 1636 G PGP G G PG KGP G+ G+ G A GPPG G GPPG QGPPGPQGP G Sbjct: 730 GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789 Query: 1637 IP-------GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 1689 P G +G +G KG+ GE G PG G G+ G G +GPPG RG G +G G Sbjct: 790 GPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRG 849 Query: 1690 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS---------GLKGEKGDRGDIASQNMM 1740 GP G PG G PG G G PG PG GR GP G GEKG RG Sbjct: 850 GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG-------- 901 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGPPGSAGARGE 1794 G+ Q P + R G PGP GP G G RG Sbjct: 902 -----------TPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950 Query: 1795 PGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP---GPQGES-RTGP 1849 GP G GFPG G GPPG+ GLPG G+RG TG G G PGPP GPQG + TGP Sbjct: 951 NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP 1010 Query: 1850 PGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G G GPPGPPG G G +G PGP G P +G+PG Sbjct: 1011 MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDG----PPGLRGFPG 1060 Score = 202 bits (515), Expect = 2e-51 Identities = 134/346 (38%), Positives = 153/346 (44%), Gaps = 74/346 (21%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-------- 1634 GPPGP GPAG PG P G G +G +G PG RG G PG G G GP G Sbjct: 469 GPPGPEGPAGLPG---PPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFR 525 Query: 1635 -----------------------------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP 1665 L++ G G G+ G G G PG G G P Sbjct: 526 FGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEP 585 Query: 1666 GPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGP---------SGKPGKPGDH 1716 G GP GP G +G G G G RG G G+ G PG TGP +G PG+ G Sbjct: 586 GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645 Query: 1717 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ 1776 G PGPSG G GD G+ R +V + + G+ + Sbjct: 646 GDPGPSGPPGPPGDDGE-------RGDDGEVGPRGLPGEPGP------------RGLLGP 686 Query: 1777 PGPPGPPGPPGSAGARGEPGPGGR---PGFPGTPGMQGPPGERGLPGEKGERG-TGSSGP 1832 GPPGPPGPPG G G+PGP G G PG PG QG PG +GLPG +G G G GP Sbjct: 687 KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP 746 Query: 1833 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G PG PG G GPPG G GPPG G G G +GP G PG Sbjct: 747 LGKPGLPGMPGAD--GPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790 Score = 199 bits (506), Expect = 2e-50 Identities = 116/245 (47%), Positives = 131/245 (53%), Gaps = 33/245 (13%) Query: 1583 GPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 GPPG PGPAG PG KG GE G +G+ GP G G GPPG +GPPGP GP G Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEG----- 1402 Query: 1640 EQGRQGMKGDAGEPGLPGRTG------TPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 1693 QG +G KG+AG G PG+TG PG PGP G G PG G G G+ GP GPPG Sbjct: 1403 RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462 Query: 1694 PPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 1750 P G PG PG+ +GP G+ G PG G GP G +GEKGDRG Q EQ Sbjct: 1463 PMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKG----EQ 1518 Query: 1751 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 1810 I+G P+ PG PGPPGP G+ G+ G GP G G PG PG Sbjct: 1519 GITG------------PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPP 1566 Query: 1811 GPPGE 1815 GPPGE Sbjct: 1567 GPPGE 1571 Score = 175 bits (443), Expect = 4e-43 Identities = 138/395 (34%), Positives = 160/395 (40%), Gaps = 95/395 (24%) Query: 1564 DEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGA--------IGPPGPR 1615 D G P S T +S P PPG G +G E I P Sbjct: 369 DPGAGAEIPTSTADTSNSSNPAPPPGE-GADDLEGEFTEETIRNLDENYYDPYYDPTSSP 427 Query: 1616 GDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAG--EPGLPGRTGTPGLPGPPGPMGP 1673 +IGP G P Q I G +G +G KG+ EPG+ + GPPGP GP Sbjct: 428 SEIGP----GMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML-------IEGPPGPEGP 476 Query: 1674 PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG----LKGEKG 1729 G GP G GP G G PG GP G+PG PG G PGP G L G Sbjct: 477 A---------GLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527 Query: 1730 DRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI------PNDYQSSRNQPGPPGPP 1783 GD S+ M +S Q ++ +L Q P +PGP GPP Sbjct: 528 GGGDAGSKGPM-----------VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP 576 Query: 1784 ------------GPPGSAGARGEPGPGGRP---------GFPGTPGMQGPPGER------ 1816 GP G G +G PGP G+P G G PG GP G+R Sbjct: 577 GSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLA 636 Query: 1817 GLPGEKGERGTGSSGPRGLPGPPGPQGE-------------SRTGPPGSTGSRGPPGPPG 1863 GLPGEKG R G GP G PGPPG GE GP G G +GPPGPPG Sbjct: 637 GLPGEKGHR--GDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPG 694 Query: 1864 RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 PG +G+ G PGP G Q P QG PG+ Sbjct: 695 PPGVTGMDGQPGPKGNV-GPQGEPGPPGQQGNPGA 728 Score = 151 bits (381), Expect = 7e-36 Identities = 94/244 (38%), Positives = 104/244 (42%), Gaps = 86/244 (35%) Query: 1581 SVGPPGPPGPAGGPGAKGP---------RGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 1631 S GP G PGP+G PG +GP +GE+G G G GP G GP GPQG PG G Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435 Query: 1632 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPG---------------------PPG 1669 P+GL IPG G QG+ G G G PG G PGLPG PPG Sbjct: 1436 PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPG 1495 Query: 1670 PMGPPGDRGFTGKDGAMGPRG------PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG 1723 G GDRG G G+ GP+G P GP G PG PG+ GP PG G G GP+G Sbjct: 1496 EQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGP---PGPKGAKGSSGPTG 1552 Query: 1724 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 1783 KGE G PGPPGPP Sbjct: 1553 PKGEAG----------------------------------------------HPGPPGPP 1566 Query: 1784 GPPG 1787 GPPG Sbjct: 1567 GPPG 1570 Score = 104 bits (259), Expect = 9e-22 Identities = 61/128 (47%), Positives = 69/128 (53%), Gaps = 20/128 (15%) Query: 1583 GPPGPPGPAGGPGAKG---PRGERG---ISGAIGPPGP---RGDIGPPGPQGPPGPQGPN 1633 GPPGP GP G PG KG P+GE+G + G IGPPG +GD G PGPQG GP+G Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518 Query: 1634 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 1693 G++ G G G G G PG PG G G GP GP G+ G GP GPPG Sbjct: 1519 GIT--GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGP---------KGEAGHPGPPGPPG 1567 Query: 1694 PPGSPGSP 1701 PPG P Sbjct: 1568 PPGEVIQP 1575 Score = 90.5 bits (223), Expect = 1e-17 Identities = 46/95 (48%), Positives = 50/95 (52%), Gaps = 14/95 (14%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQ 1641 +GPPG G G G GP+G G G G GP G IGPPGP G PGP GP G G Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAK--GSS 1548 Query: 1642 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 1676 G G KG+AG PGPPGP GPPG+ Sbjct: 1549 GPTGPKGEAGH------------PGPPGPPGPPGE 1571 Score = 73.2 bits (178), Expect = 2e-12 Identities = 34/74 (45%), Positives = 41/74 (55%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 1638 Q GP GP GP G PG GP G +G G+ GP GP+G+ G PGP GPPGP G +P Sbjct: 1518 QGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577 Query: 1639 GEQGRQGMKGDAGE 1652 + R DA + Sbjct: 1578 IQASRTRRNIDASQ 1591 Score = 33.9 bits (76), Expect = 1.6 Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 7/146 (4%) Query: 1358 KMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHP-NGLPPSYTII 1416 K+L+ +NL + + + S AYR+ K+A ++ PT L+P + P ++I+ Sbjct: 44 KVLDFHNLPDGITKTTGFCATRRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSIL 103 Query: 1417 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV 1476 + + S F + I + Q+G+ ++ F +D G+ + Sbjct: 104 TTVK--AKKGSQAFLV-SIYNEQGIQQIGL---ELGRSPVFLYEDHTGKPGPEDYPLFRG 157 Query: 1477 KTLFYGSFHKVHIVVTSKSVKIYIDC 1502 L G +H++ + V K+V + +DC Sbjct: 158 INLSDGKWHRIALSVHKKNVTLILDC 183 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 254 bits (650), Expect = 4e-67 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 1630 GPPGPPG G PG G RGE G G GPPGP G +GP GP G PPGP Sbjct: 946 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 1005 Query: 1631 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 1690 G GL PG G++G KGD G G+ G+ G GL G PG G PG +G G G GP+G Sbjct: 1006 GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1063 Query: 1691 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 1743 PPGP GSP GS G GP G PG+PG G PGP+G K GEKG +G + V Sbjct: 1064 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1123 Query: 1744 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 1790 A E G++ Q + + + GPPGPP G PG AG Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1177 Query: 1791 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 1840 GEPGP G+ G G PG GP G +GLPG GE+G G GP G PGPPG Sbjct: 1178 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237 Query: 1841 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 P+G + GPPGS GS G G G PG +G GPPG G Sbjct: 1238 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282 Score = 249 bits (635), Expect = 2e-65 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%) Query: 1567 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 1626 K P P Q VG PGP GPAG PG G +GE G G G G +G+ GPPGP G Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166 Query: 1627 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 1669 GP G G++ PG +G+QGM G G+ PG PG G GLPGPPG Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1226 Query: 1670 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 1727 PMGPPG G G G G GP GPPGS GS G G G+PG+ G+ G PG +G+ G Sbjct: 1227 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1286 Query: 1728 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 1787 KG+RG+ A +G + P PG PGPPG PG Sbjct: 1287 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336 Query: 1788 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 1845 AG G G G G PG PG GP GE G PG G+RG G++G G G G +GE+ Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1396 Query: 1846 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GPPG TG GP GP G+PG G+RG PGP G Sbjct: 1397 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1429 Score = 242 bits (618), Expect = 2e-63 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 1641 GPPGP G G PG G +GE G G +GPPGP G GP GP G GPQGP G + G Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1263 Query: 1642 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 1686 G +G G+AG PG PG G PG GPPG GPPGD G G G + Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323 Query: 1687 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 1724 G G PGPPG PG PG GPSG+ G PG G+ GP G Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383 Query: 1725 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 1777 +GEKG +G+ ++ V Q +G+ + L IP + Q Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1440 Query: 1778 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 1833 GPPGP GPPG G +G+PG G G PG G+ GPPGE+G G++G GT G+ G Sbjct: 1441 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1500 Query: 1834 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G+PGP GP G GP G G++G GP G+ G+SG+ GPPG PG Sbjct: 1501 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Score = 239 bits (611), Expect = 1e-62 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%) Query: 1582 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 1634 +GP G PG AG G GPR G+ G++G GPPGP+G++GP G GPPG QG P Sbjct: 651 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 1694 +PG QG G G+ G G PG G PG GPP G PG G +G+ GA+GP GP GP Sbjct: 711 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 767 Query: 1695 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 1754 G PG GV G G G G G G G G KGD G + G Sbjct: 768 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 808 Query: 1755 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 1814 Q+ + + + + + GP G PGP G AG +G+ G PG PG PG QGP G Sbjct: 809 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 865 Query: 1815 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 1873 G PG G G G RG+ G PGP+G+ TGP GS G+RGP G PG G SG GP Sbjct: 866 STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923 Query: 1874 PGPPGYCDSSQCASIPYNGQGYPG 1897 PGPPG + P G+PG Sbjct: 924 PGPPG----ERGPQGPQGPVGFPG 943 Score = 239 bits (611), Expect = 1e-62 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P P + G PGP G +GG G GP GERG P GP+G +G PGP+GPPG Sbjct: 896 PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 949 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 P PG+ G G G GE G G+TG PG G GP GP G+ G G+ G GP Sbjct: 950 P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001 Query: 1689 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 1748 GPPG G PG+ G G G PG G G+ GP+GL+G G+RG +Q Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1052 Query: 1749 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 1808 + GP GPPGP GS G RG G G G PG PG Sbjct: 1053 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1090 Query: 1809 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 1861 QGPP GE+G PGEKG +G G GP GLPGP GP G G G G G PG Sbjct: 1091 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1148 Query: 1862 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G G+ G GPPGPPG I G G PG Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1183 Score = 239 bits (609), Expect = 2e-62 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%) Query: 1583 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 1632 GPPGP PGP GGPG+ G +GE SG GP GPRG GPPGP G PG +G Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597 Query: 1633 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 1692 G +PGE G +G +G G PGLPG G G GP GP GPPGD G G+DG +GPRG P Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 657 Query: 1693 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 GP G+PG+PG G +G G PG G GP G G G +G+ Q Sbjct: 658 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 712 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 1797 + G + P PG GPPG PG G GE PGP Sbjct: 713 --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 764 Query: 1798 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 1846 G G+PG G++G G RGL G KGE+G G G RG G GP+GE Sbjct: 765 QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 824 Query: 1847 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GP G G G PGP G+ G G G PG PGY P G+PG Sbjct: 825 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 871 Score = 227 bits (579), Expect = 7e-59 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 1613 ++GPPGP GP G PG +G +G G+ G +G G Sbjct: 758 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 817 Query: 1614 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 1658 PRG+ GP GP+G GP G G S +PG GRQG KG G PG PG Sbjct: 818 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 877 Query: 1659 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 1705 G PG G GP GP G RG G G GP+ GPPGPPG G G G Sbjct: 878 EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 937 Query: 1706 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 1763 P G PG G G PG GL G G RG+ Q V Q +G+ + Sbjct: 938 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 995 Query: 1764 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 1817 R PGPPGPPG PG+A GA+G+PGP G G G G++G PGERG Sbjct: 996 ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 1045 Query: 1818 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 1869 LPG +G G G GP+G PGP PG +G + T G PG G +GPPGP G G G Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105 Query: 1870 IRGPPGPPG 1878 +GP GP G Sbjct: 1106 EKGPQGPAG 1114 Score = 224 bits (571), Expect = 6e-58 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 1627 GPPGP G G G GP G++G G G PGP+G IGPPG PQG PP Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 744 Query: 1628 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 1671 GP GP G + PG +G +G G G G G G G PG G M Sbjct: 745 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 804 Query: 1672 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 1731 G GDRG G+ G G GP GP G G G GPSG+ G+ G G PG G G +G + Sbjct: 805 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864 Query: 1732 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 1785 G A + ++G+ Q P + +R G PGP GP Sbjct: 865 GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923 Query: 1786 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 1838 PG G RG GP G GFPG G GPPG+ GLPG G+RG TG GP G+ GP Sbjct: 924 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983 Query: 1839 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 1892 GP GE TGP G G GPPGPPG G G +G PGP G A + Sbjct: 984 QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 1037 Query: 1893 QGYPG 1897 +G+PG Sbjct: 1038 RGFPG 1042 Score = 210 bits (534), Expect = 1e-53 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%) Query: 1583 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 1630 GPPGP GPAG PG +GP G G G GPPG G G G GPPG Sbjct: 454 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 1631 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 1680 G G +I + Q R ++G G GL GR G G PG G G GD G Sbjct: 514 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 573 Query: 1681 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 1737 G G GP GP G PG G PG G G PG+P GD G G GL G+KG RG+ Q Sbjct: 574 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 633 Query: 1738 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 1797 P R + G GP G PG AG RG GP Sbjct: 634 GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 668 Query: 1798 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 1843 G PG PG PGM GPPG +G G +GE G G+ GP+GLPGP GP G Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728 Query: 1844 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 + + G G G+ GPPG PG+ G SG +G GPPG P GYPG Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 772 Score = 201 bits (512), Expect = 4e-51 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GPPG PGPAG G G +GE G G GPPGP G+ GPPGP G GP G G G QG Sbjct: 1330 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1387 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 1699 +G KG+AG G PG+TG G GP G GP G RG G+ G G G GPPG G Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447 Query: 1700 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 1759 PG+ G G PG G+ G PG GL G G++G+ Sbjct: 1448 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1481 Query: 1760 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 1819 + R PG G PG G G G GP G PG PG PG QGP G +G Sbjct: 1482 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530 Query: 1820 GEKGERG-TGSSGPRGLPGPPG 1840 G G++G +G GP G PGPPG Sbjct: 1531 GPAGQKGDSGLPGPPGSPGPPG 1552 Score = 177 bits (449), Expect = 9e-44 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%) Query: 1584 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 1635 P PP GPG A+ E I+G A G G +G+ + PG +GPPGP GP G+ Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 1695 G PGL GP GP G PGDRG G+ G G G PGPP Sbjct: 465 M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 501 Query: 1696 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 1722 G+ GS G T GP G G+PG G PG S Sbjct: 502 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 561 Query: 1723 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 1782 G KGE GD G + + G + + R PG PG Sbjct: 562 GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 608 Query: 1783 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 1830 PG PG G RGE GP G PG PG GM+G GE RGLPGE G RG Sbjct: 609 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 666 Query: 1831 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 1878 GPRG PG PG G + GPPG G+ GP PGPPG+ GN G +G PGP G Sbjct: 667 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718 Score = 137 bits (346), Expect = 8e-32 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 1634 GP G PGP G G GP GE+G+ GA G PPGP G G PG +G PG +G G Sbjct: 1411 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1470 Query: 1635 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 1692 + PGEQG +G +G G G PG G G+PGP GP+GPPG G G G G +G Sbjct: 1471 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530 Query: 1693 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 1721 GP G G G+ GP G PG PG+ +P P Sbjct: 1531 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559 Score = 130 bits (327), Expect = 1e-29 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 + G GPPGP G PG G +G+ G G G PG G IGPPG QG G +G +PG Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1490 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 QG G KGD G PG G G PG PG PGP GP G++G TG G G G PGPPGSPG Sbjct: 1491 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1550 Query: 1701 PG 1702 PG Sbjct: 1551 PG 1552 Score = 90.5 bits (223), Expect = 1e-17 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 1614 +GPPG PG G PG+KG +G G+ G IGPPG P Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1505 Query: 1615 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 1674 G +GPPGP G PGPQGP G G G G KGD+G P G PG PGPPG + P Sbjct: 1506 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1557 Score = 58.2 bits (139), Expect = 8e-08 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%) Query: 1769 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 1812 +Y+ ++P PP PG P GA GE G G P PGM +GP Sbjct: 397 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 455 Query: 1813 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 1872 PG +GP G+ GPPG QG TGPPG G R G PG G+ G Sbjct: 456 PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 493 Query: 1873 PPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG + Y G G G Sbjct: 494 ADGLPGPPGTMLMLPFRYGGDGSKG 518 Score = 47.0 bits (110), Expect = 2e-04 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%) Query: 1372 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 1424 S +G+S +G S S +AYR+ K A ++ PT L P G P +LF + P+ Sbjct: 50 SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108 Query: 1425 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 1484 F + I + Q+GV ++ F +D G+ + + G + Sbjct: 109 KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 1485 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 1542 H+V I V K+V + +DC + K D E + T+G + G + E IQ F Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223 Query: 1543 DIVCSP 1548 I P Sbjct: 224 LITGDP 229 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 254 bits (650), Expect = 4e-67 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 1630 GPPGPPG G PG G RGE G G GPPGP G +GP GP G PPGP Sbjct: 895 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954 Query: 1631 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 1690 G GL PG G++G KGD G G+ G+ G GL G PG G PG +G G G GP+G Sbjct: 955 GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012 Query: 1691 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 1743 PPGP GSP GS G GP G PG+PG G PGP+G K GEKG +G + V Sbjct: 1013 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072 Query: 1744 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 1790 A E G++ Q + + + GPPGPP G PG AG Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1126 Query: 1791 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 1840 GEPGP G+ G G PG GP G +GLPG GE+G G GP G PGPPG Sbjct: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186 Query: 1841 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 P+G + GPPGS GS G G G PG +G GPPG G Sbjct: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231 Score = 249 bits (635), Expect = 2e-65 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%) Query: 1567 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 1626 K P P Q VG PGP GPAG PG G +GE G G G G +G+ GPPGP G Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115 Query: 1627 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 1669 GP G G++ PG +G+QGM G G+ PG PG G GLPGPPG Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1175 Query: 1670 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 1727 PMGPPG G G G G GP GPPGS GS G G G+PG+ G+ G PG +G+ G Sbjct: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1235 Query: 1728 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 1787 KG+RG+ A +G + P PG PGPPG PG Sbjct: 1236 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285 Query: 1788 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 1845 AG G G G G PG PG GP GE G PG G+RG G++G G G G +GE+ Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1345 Query: 1846 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GPPG TG GP GP G+PG G+RG PGP G Sbjct: 1346 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1378 Score = 242 bits (618), Expect = 2e-63 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 1641 GPPGP G G PG G +GE G G +GPPGP G GP GP G GPQGP G + G Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1212 Query: 1642 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 1686 G +G G+AG PG PG G PG GPPG GPPGD G G G + Sbjct: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272 Query: 1687 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 1724 G G PGPPG PG PG GPSG+ G PG G+ GP G Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332 Query: 1725 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 1777 +GEKG +G+ ++ V Q +G+ + L IP + Q Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1389 Query: 1778 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 1833 GPPGP GPPG G +G+PG G G PG G+ GPPGE+G G++G GT G+ G Sbjct: 1390 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1449 Query: 1834 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G+PGP GP G GP G G++G GP G+ G+SG+ GPPG PG Sbjct: 1450 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Score = 239 bits (611), Expect = 1e-62 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%) Query: 1582 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 1634 +GP G PG AG G GPR G+ G++G GPPGP+G++GP G GPPG QG P Sbjct: 600 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 1694 +PG QG G G+ G G PG G PG GPP G PG G +G+ GA+GP GP GP Sbjct: 660 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 716 Query: 1695 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 1754 G PG GV G G G G G G G G KGD G + G Sbjct: 717 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 757 Query: 1755 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 1814 Q+ + + + + + GP G PGP G AG +G+ G PG PG PG QGP G Sbjct: 758 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 814 Query: 1815 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 1873 G PG G G G RG+ G PGP+G+ TGP GS G+RGP G PG G SG GP Sbjct: 815 STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872 Query: 1874 PGPPGYCDSSQCASIPYNGQGYPG 1897 PGPPG + P G+PG Sbjct: 873 PGPPG----ERGPQGPQGPVGFPG 892 Score = 239 bits (611), Expect = 1e-62 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P P + G PGP G +GG G GP GERG P GP+G +G PGP+GPPG Sbjct: 845 PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 898 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 P PG+ G G G GE G G+TG PG G GP GP G+ G G+ G GP Sbjct: 899 P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950 Query: 1689 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 1748 GPPG G PG+ G G G PG G G+ GP+GL+G G+RG +Q Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1001 Query: 1749 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 1808 + GP GPPGP GS G RG G G G PG PG Sbjct: 1002 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1039 Query: 1809 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 1861 QGPP GE+G PGEKG +G G GP GLPGP GP G G G G G PG Sbjct: 1040 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1097 Query: 1862 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G G+ G GPPGPPG I G G PG Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1132 Score = 239 bits (609), Expect = 2e-62 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%) Query: 1583 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 1632 GPPGP PGP GGPG+ G +GE SG GP GPRG GPPGP G PG +G Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546 Query: 1633 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 1692 G +PGE G +G +G G PGLPG G G GP GP GPPGD G G+DG +GPRG P Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 606 Query: 1693 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 GP G+PG+PG G +G G PG G GP G G G +G+ Q Sbjct: 607 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 661 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 1797 + G + P PG GPPG PG G GE PGP Sbjct: 662 --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 713 Query: 1798 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 1846 G G+PG G++G G RGL G KGE+G G G RG G GP+GE Sbjct: 714 QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 773 Query: 1847 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GP G G G PGP G+ G G G PG PGY P G+PG Sbjct: 774 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 820 Score = 227 bits (579), Expect = 7e-59 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 1613 ++GPPGP GP G PG +G +G G+ G +G G Sbjct: 707 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 766 Query: 1614 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 1658 PRG+ GP GP+G GP G G S +PG GRQG KG G PG PG Sbjct: 767 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826 Query: 1659 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 1705 G PG G GP GP G RG G G GP+ GPPGPPG G G G Sbjct: 827 EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 886 Query: 1706 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 1763 P G PG G G PG GL G G RG+ Q V Q +G+ + Sbjct: 887 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 944 Query: 1764 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 1817 R PGPPGPPG PG+A GA+G+PGP G G G G++G PGERG Sbjct: 945 ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 994 Query: 1818 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 1869 LPG +G G G GP+G PGP PG +G + T G PG G +GPPGP G G G Sbjct: 995 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054 Query: 1870 IRGPPGPPG 1878 +GP GP G Sbjct: 1055 EKGPQGPAG 1063 Score = 224 bits (571), Expect = 6e-58 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 1627 GPPGP G G G GP G++G G G PGP+G IGPPG PQG PP Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693 Query: 1628 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 1671 GP GP G + PG +G +G G G G G G G PG G M Sbjct: 694 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753 Query: 1672 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 1731 G GDRG G+ G G GP GP G G G GPSG+ G+ G G PG G G +G + Sbjct: 754 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813 Query: 1732 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 1785 G A + ++G+ Q P + +R G PGP GP Sbjct: 814 GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872 Query: 1786 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 1838 PG G RG GP G GFPG G GPPG+ GLPG G+RG TG GP G+ GP Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932 Query: 1839 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 1892 GP GE TGP G G GPPGPPG G G +G PGP G A + Sbjct: 933 QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 986 Query: 1893 QGYPG 1897 +G+PG Sbjct: 987 RGFPG 991 Score = 210 bits (534), Expect = 1e-53 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%) Query: 1583 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 1630 GPPGP GPAG PG +GP G G G GPPG G G G GPPG Sbjct: 403 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 1631 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 1680 G G +I + Q R ++G G GL GR G G PG G G GD G Sbjct: 463 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 522 Query: 1681 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 1737 G G GP GP G PG G PG G G PG+P GD G G GL G+KG RG+ Q Sbjct: 523 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 582 Query: 1738 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 1797 P R + G GP G PG AG RG GP Sbjct: 583 GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 617 Query: 1798 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 1843 G PG PG PGM GPPG +G G +GE G G+ GP+GLPGP GP G Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677 Query: 1844 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 + + G G G+ GPPG PG+ G SG +G GPPG P GYPG Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 721 Score = 201 bits (512), Expect = 4e-51 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GPPG PGPAG G G +GE G G GPPGP G+ GPPGP G GP G G G QG Sbjct: 1279 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1336 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 1699 +G KG+AG G PG+TG G GP G GP G RG G+ G G G GPPG G Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396 Query: 1700 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 1759 PG+ G G PG G+ G PG GL G G++G+ Sbjct: 1397 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1430 Query: 1760 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 1819 + R PG G PG G G G GP G PG PG PG QGP G +G Sbjct: 1431 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479 Query: 1820 GEKGERG-TGSSGPRGLPGPPG 1840 G G++G +G GP G PGPPG Sbjct: 1480 GPAGQKGDSGLPGPPGSPGPPG 1501 Score = 177 bits (449), Expect = 9e-44 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%) Query: 1584 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 1635 P PP GPG A+ E I+G A G G +G+ + PG +GPPGP GP G+ Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 1695 G PGL GP GP G PGDRG G+ G G G PGPP Sbjct: 414 M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 450 Query: 1696 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 1722 G+ GS G T GP G G+PG G PG S Sbjct: 451 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 510 Query: 1723 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 1782 G KGE GD G + + G + + R PG PG Sbjct: 511 GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 557 Query: 1783 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 1830 PG PG G RGE GP G PG PG GM+G GE RGLPGE G RG Sbjct: 558 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 615 Query: 1831 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 1878 GPRG PG PG G + GPPG G+ GP PGPPG+ GN G +G PGP G Sbjct: 616 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667 Score = 137 bits (346), Expect = 8e-32 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 1634 GP G PGP G G GP GE+G+ GA G PPGP G G PG +G PG +G G Sbjct: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1419 Query: 1635 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 1692 + PGEQG +G +G G G PG G G+PGP GP+GPPG G G G G +G Sbjct: 1420 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479 Query: 1693 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 1721 GP G G G+ GP G PG PG+ +P P Sbjct: 1480 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508 Score = 130 bits (327), Expect = 1e-29 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 + G GPPGP G PG G +G+ G G G PG G IGPPG QG G +G +PG Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1439 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 QG G KGD G PG G G PG PG PGP GP G++G TG G G G PGPPGSPG Sbjct: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1499 Query: 1701 PG 1702 PG Sbjct: 1500 PG 1501 Score = 90.5 bits (223), Expect = 1e-17 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 1614 +GPPG PG G PG+KG +G G+ G IGPPG P Sbjct: 1395 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1454 Query: 1615 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 1674 G +GPPGP G PGPQGP G G G G KGD+G P G PG PGPPG + P Sbjct: 1455 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1506 Score = 58.2 bits (139), Expect = 8e-08 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%) Query: 1769 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 1812 +Y+ ++P PP PG P GA GE G G P PGM +GP Sbjct: 346 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 404 Query: 1813 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 1872 PG +GP G+ GPPG QG TGPPG G R G PG G+ G Sbjct: 405 PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 442 Query: 1873 PPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG + Y G G G Sbjct: 443 ADGLPGPPGTMLMLPFRYGGDGSKG 467 Score = 47.0 bits (110), Expect = 2e-04 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%) Query: 1372 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 1424 S +G+S +G S S +AYR+ K A ++ PT L P G P +LF + P+ Sbjct: 50 SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108 Query: 1425 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 1484 F + I + Q+GV ++ F +D G+ + + G + Sbjct: 109 KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 1485 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 1542 H+V I V K+V + +DC + K D E + T+G + G + E IQ F Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223 Query: 1543 DIVCSP 1548 I P Sbjct: 224 LITGDP 229 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 254 bits (650), Expect = 4e-67 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 1630 GPPGPPG G PG G RGE G G GPPGP G +GP GP G PPGP Sbjct: 934 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993 Query: 1631 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 1690 G GL PG G++G KGD G G+ G+ G GL G PG G PG +G G G GP+G Sbjct: 994 GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051 Query: 1691 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 1743 PPGP GSP GS G GP G PG+PG G PGP+G K GEKG +G + V Sbjct: 1052 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111 Query: 1744 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 1790 A E G++ Q + + + GPPGPP G PG AG Sbjct: 1112 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1165 Query: 1791 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 1840 GEPGP G+ G G PG GP G +GLPG GE+G G GP G PGPPG Sbjct: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225 Query: 1841 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 P+G + GPPGS GS G G G PG +G GPPG G Sbjct: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270 Score = 249 bits (635), Expect = 2e-65 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%) Query: 1567 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 1626 K P P Q VG PGP GPAG PG G +GE G G G G +G+ GPPGP G Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154 Query: 1627 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 1669 GP G G++ PG +G+QGM G G+ PG PG G GLPGPPG Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1214 Query: 1670 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 1727 PMGPPG G G G G GP GPPGS GS G G G+PG+ G+ G PG +G+ G Sbjct: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1274 Query: 1728 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 1787 KG+RG+ A +G + P PG PGPPG PG Sbjct: 1275 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324 Query: 1788 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 1845 AG G G G G PG PG GP GE G PG G+RG G++G G G G +GE+ Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1384 Query: 1846 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GPPG TG GP GP G+PG G+RG PGP G Sbjct: 1385 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417 Score = 242 bits (618), Expect = 2e-63 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 1641 GPPGP G G PG G +GE G G +GPPGP G GP GP G GPQGP G + G Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1251 Query: 1642 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 1686 G +G G+AG PG PG G PG GPPG GPPGD G G G + Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311 Query: 1687 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 1724 G G PGPPG PG PG GPSG+ G PG G+ GP G Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371 Query: 1725 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 1777 +GEKG +G+ ++ V Q +G+ + L IP + Q Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1428 Query: 1778 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 1833 GPPGP GPPG G +G+PG G G PG G+ GPPGE+G G++G GT G+ G Sbjct: 1429 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1488 Query: 1834 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G+PGP GP G GP G G++G GP G+ G+SG+ GPPG PG Sbjct: 1489 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537 Score = 239 bits (611), Expect = 1e-62 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%) Query: 1582 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 1634 +GP G PG AG G GPR G+ G++G GPPGP+G++GP G GPPG QG P Sbjct: 639 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 1694 +PG QG G G+ G G PG G PG GPP G PG G +G+ GA+GP GP GP Sbjct: 699 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 755 Query: 1695 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 1754 G PG GV G G G G G G G G KGD G + G Sbjct: 756 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 796 Query: 1755 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 1814 Q+ + + + + + GP G PGP G AG +G+ G PG PG PG QGP G Sbjct: 797 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 853 Query: 1815 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 1873 G PG G G G RG+ G PGP+G+ TGP GS G+RGP G PG G SG GP Sbjct: 854 STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911 Query: 1874 PGPPGYCDSSQCASIPYNGQGYPG 1897 PGPPG + P G+PG Sbjct: 912 PGPPG----ERGPQGPQGPVGFPG 931 Score = 239 bits (611), Expect = 1e-62 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P P + G PGP G +GG G GP GERG P GP+G +G PGP+GPPG Sbjct: 884 PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 937 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 P PG+ G G G GE G G+TG PG G GP GP G+ G G+ G GP Sbjct: 938 P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989 Query: 1689 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 1748 GPPG G PG+ G G G PG G G+ GP+GL+G G+RG +Q Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1040 Query: 1749 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 1808 + GP GPPGP GS G RG G G G PG PG Sbjct: 1041 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1078 Query: 1809 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 1861 QGPP GE+G PGEKG +G G GP GLPGP GP G G G G G PG Sbjct: 1079 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1136 Query: 1862 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G G+ G GPPGPPG I G G PG Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1171 Score = 239 bits (609), Expect = 2e-62 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%) Query: 1583 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 1632 GPPGP PGP GGPG+ G +GE SG GP GPRG GPPGP G PG +G Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585 Query: 1633 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 1692 G +PGE G +G +G G PGLPG G G GP GP GPPGD G G+DG +GPRG P Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 645 Query: 1693 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 GP G+PG+PG G +G G PG G GP G G G +G+ Q Sbjct: 646 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 700 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 1797 + G + P PG GPPG PG G GE PGP Sbjct: 701 --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 752 Query: 1798 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 1846 G G+PG G++G G RGL G KGE+G G G RG G GP+GE Sbjct: 753 QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 812 Query: 1847 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GP G G G PGP G+ G G G PG PGY P G+PG Sbjct: 813 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 859 Score = 227 bits (579), Expect = 7e-59 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 1613 ++GPPGP GP G PG +G +G G+ G +G G Sbjct: 746 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 805 Query: 1614 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 1658 PRG+ GP GP+G GP G G S +PG GRQG KG G PG PG Sbjct: 806 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865 Query: 1659 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 1705 G PG G GP GP G RG G G GP+ GPPGPPG G G G Sbjct: 866 EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 925 Query: 1706 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 1763 P G PG G G PG GL G G RG+ Q V Q +G+ + Sbjct: 926 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 983 Query: 1764 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 1817 R PGPPGPPG PG+A GA+G+PGP G G G G++G PGERG Sbjct: 984 ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 1033 Query: 1818 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 1869 LPG +G G G GP+G PGP PG +G + T G PG G +GPPGP G G G Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093 Query: 1870 IRGPPGPPG 1878 +GP GP G Sbjct: 1094 EKGPQGPAG 1102 Score = 224 bits (571), Expect = 6e-58 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 1627 GPPGP G G G GP G++G G G PGP+G IGPPG PQG PP Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732 Query: 1628 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 1671 GP GP G + PG +G +G G G G G G G PG G M Sbjct: 733 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 792 Query: 1672 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 1731 G GDRG G+ G G GP GP G G G GPSG+ G+ G G PG G G +G + Sbjct: 793 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852 Query: 1732 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 1785 G A + ++G+ Q P + +R G PGP GP Sbjct: 853 GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911 Query: 1786 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 1838 PG G RG GP G GFPG G GPPG+ GLPG G+RG TG GP G+ GP Sbjct: 912 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971 Query: 1839 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 1892 GP GE TGP G G GPPGPPG G G +G PGP G A + Sbjct: 972 QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 1025 Query: 1893 QGYPG 1897 +G+PG Sbjct: 1026 RGFPG 1030 Score = 210 bits (534), Expect = 1e-53 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%) Query: 1583 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 1630 GPPGP GPAG PG +GP G G G GPPG G G G GPPG Sbjct: 442 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 501 Query: 1631 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 1680 G G +I + Q R ++G G GL GR G G PG G G GD G Sbjct: 502 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 561 Query: 1681 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 1737 G G GP GP G PG G PG G G PG+P GD G G GL G+KG RG+ Q Sbjct: 562 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 621 Query: 1738 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 1797 P R + G GP G PG AG RG GP Sbjct: 622 GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 656 Query: 1798 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 1843 G PG PG PGM GPPG +G G +GE G G+ GP+GLPGP GP G Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716 Query: 1844 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 + + G G G+ GPPG PG+ G SG +G GPPG P GYPG Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 760 Score = 201 bits (512), Expect = 4e-51 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GPPG PGPAG G G +GE G G GPPGP G+ GPPGP G GP G G G QG Sbjct: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1375 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 1699 +G KG+AG G PG+TG G GP G GP G RG G+ G G G GPPG G Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435 Query: 1700 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 1759 PG+ G G PG G+ G PG GL G G++G+ Sbjct: 1436 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1469 Query: 1760 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 1819 + R PG G PG G G G GP G PG PG PG QGP G +G Sbjct: 1470 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518 Query: 1820 GEKGERG-TGSSGPRGLPGPPG 1840 G G++G +G GP G PGPPG Sbjct: 1519 GPAGQKGDSGLPGPPGSPGPPG 1540 Score = 177 bits (449), Expect = 9e-44 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%) Query: 1584 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 1635 P PP GPG A+ E I+G A G G +G+ + PG +GPPGP GP G+ Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 1695 G PGL GP GP G PGDRG G+ G G G PGPP Sbjct: 453 M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 489 Query: 1696 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 1722 G+ GS G T GP G G+PG G PG S Sbjct: 490 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 549 Query: 1723 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 1782 G KGE GD G + + G + + R PG PG Sbjct: 550 GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 596 Query: 1783 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 1830 PG PG G RGE GP G PG PG GM+G GE RGLPGE G RG Sbjct: 597 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 654 Query: 1831 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 1878 GPRG PG PG G + GPPG G+ GP PGPPG+ GN G +G PGP G Sbjct: 655 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706 Score = 137 bits (346), Expect = 8e-32 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 1634 GP G PGP G G GP GE+G+ GA G PPGP G G PG +G PG +G G Sbjct: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1458 Query: 1635 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 1692 + PGEQG +G +G G G PG G G+PGP GP+GPPG G G G G +G Sbjct: 1459 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518 Query: 1693 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 1721 GP G G G+ GP G PG PG+ +P P Sbjct: 1519 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547 Score = 130 bits (327), Expect = 1e-29 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 + G GPPGP G PG G +G+ G G G PG G IGPPG QG G +G +PG Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1478 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 QG G KGD G PG G G PG PG PGP GP G++G TG G G G PGPPGSPG Sbjct: 1479 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1538 Query: 1701 PG 1702 PG Sbjct: 1539 PG 1540 Score = 90.5 bits (223), Expect = 1e-17 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 1614 +GPPG PG G PG+KG +G G+ G IGPPG P Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1493 Query: 1615 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 1674 G +GPPGP G PGPQGP G G G G KGD+G P G PG PGPPG + P Sbjct: 1494 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1545 Score = 58.2 bits (139), Expect = 8e-08 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%) Query: 1769 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 1812 +Y+ ++P PP PG P GA GE G G P PGM +GP Sbjct: 385 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 443 Query: 1813 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 1872 PG +GP G+ GPPG QG TGPPG G R G PG G+ G Sbjct: 444 PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 481 Query: 1873 PPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG + Y G G G Sbjct: 482 ADGLPGPPGTMLMLPFRYGGDGSKG 506 Score = 47.0 bits (110), Expect = 2e-04 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%) Query: 1372 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 1424 S +G+S +G S S +AYR+ K A ++ PT L P G P +LF + P+ Sbjct: 50 SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108 Query: 1425 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 1484 F + I + Q+GV ++ F +D G+ + + G + Sbjct: 109 KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 1485 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 1542 H+V I V K+V + +DC + K D E + T+G + G + E IQ F Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223 Query: 1543 DIVCSP 1548 I P Sbjct: 224 LITGDP 229 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 254 bits (649), Expect = 6e-67 Identities = 165/405 (40%), Positives = 185/405 (45%), Gaps = 88/405 (21%) Query: 1579 QDSVGPPGPPGPA-----GGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPN 1633 Q G PGPPGP+ G PG G GERG G G GP G GP GP GPPG GP Sbjct: 91 QGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPA 150 Query: 1634 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP--------------------------GP 1667 G+S+PG+ G+QG G G G PG G PG+P GP Sbjct: 151 GISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGP 210 Query: 1668 PGPMGPP-----------------GDRGFTGKDGAMGPRGPPGPP--------------G 1696 GP GPP GDRGF G+ G +GP GP GPP G Sbjct: 211 TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270 Query: 1697 SPGSPGVTGPSGKPGKPGDHGRPGP-----SGLKGEKGDRGDIASQNMMRAVARQVCEQL 1751 +PG PG+ G G PG PG G PGP GL G KG+RG A Q L Sbjct: 271 APGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGL 330 Query: 1752 IS--GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP------PGSAGARGEPGPGGRPGF 1803 G M Q P S PGP G GP PG+ G RG PG G+PG+ Sbjct: 331 PGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGY 390 Query: 1804 PGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG-------ESRTGP---PGST 1853 PG PG+ GP G GLPG KG+ G G GP GLPGP GP G GP PG Sbjct: 391 PGKPGLDGPKGNPGLPGPKGDPGVG--GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIP 448 Query: 1854 GSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG-QGYPG 1897 G+RGP GPPG PG G +G PG PG + A+ NG G PG Sbjct: 449 GTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPG 493 Score = 244 bits (622), Expect = 8e-64 Identities = 144/328 (43%), Positives = 158/328 (48%), Gaps = 51/328 (15%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGP------PGPRGDIGPPGPQGPPGPQGPNGLS 1636 GP GP GP+G PG G RGE G+ G G PG G IGPPGPQGPPG +GP G+ Sbjct: 206 GPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIG 264 Query: 1637 IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPG-----------PMGPPGDRGFTGKDGA 1685 PG G G G G GLPG G G PGPPG GP G G G G Sbjct: 265 KPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGE 324 Query: 1686 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP---------SGLKGEKGDRGDIAS 1736 GP G PG PG G PG GP G G PG HG PGP +G G KG+RG S Sbjct: 325 QGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGS 384 Query: 1737 QNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG 1796 + G+ N + GPPG PGP G AGA+G PG Sbjct: 385 DG----------KPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPG 434 Query: 1797 ------PGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPP 1850 P G PG PGT G GPPG G PG KG+ G+ PGPPGP G + G Sbjct: 435 HNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS--------PGPPGPAGIATKGLN 486 Query: 1851 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G TG GPPGP G G G+ GPPGPPG Sbjct: 487 GPTGPPGPPGPRGHSGEPGLPGPPGPPG 514 Score = 235 bits (599), Expect = 4e-61 Identities = 153/358 (42%), Positives = 176/358 (49%), Gaps = 63/358 (17%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPP--GPQGPNGL- 1635 Q + GPPGP GP G PG GP G+ G G PG +G+ G PGP GP G G GL Sbjct: 59 QGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPSAVGKPGVPGLP 114 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--PPGDRGFTGKDGAMGPRGPPG 1693 PGE+G G KGD G GLPG G PG PG PGP G PG G G GA GPRG PG Sbjct: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174 Query: 1694 PPGSPGSPGVTGPSGK-----PGKPGDHGRPGPSGLKGEKGDRG-DIASQNMMRAVARQV 1747 G+PG PG+ G G+ PG+PG+ G PGP G G G G +N + Sbjct: 175 EKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIK 234 Query: 1748 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP--------GPPGSAGARGEPGPGG 1799 ++ G+M PGP GPP G PG+AGA G+PG G Sbjct: 235 GDRGFPGEMGPI---------------GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPG 279 Query: 1800 RPGFPGTPGMQGPP-----GERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE 1844 G PG PG+ GPP G+ GLPG KGERG G GP GLPG PG Sbjct: 280 TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG---- 335 Query: 1845 SRTGPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG--QGYPG 1897 TGPPG+ G +GP PG G PG G GP GP GY + P + GYPG Sbjct: 336 -LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392 Score = 223 bits (569), Expect = 1e-57 Identities = 130/286 (45%), Positives = 146/286 (51%), Gaps = 37/286 (12%) Query: 1603 RGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTP 1662 RG G GPPGP G G PGP GPPG G PG QG G+ G G P G+ G P Sbjct: 56 RGEQGTPGPPGPAGPRGHPGPSGPPGKP---GYGSPGLQGEPGLPGPPG-PSAVGKPGVP 111 Query: 1663 GLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS 1722 GLPG PG GP G +G G G GPRGPPGPPG PG G++ P GKPG+ G G PGP Sbjct: 112 GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGPR 170 Query: 1723 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 1782 G GEKG G + G + +M P R PGP GP Sbjct: 171 GFPGEKGAPG-------------------VPGMNGQKGEMGYGAPG-RPGERGLPGPQGP 210 Query: 1783 PGP--PGSAGARGEPGPGGRP------GFPGTPGMQGPPGERGLPGEKGERGTGSSGPRG 1834 GP P G RGE G G+P GFPG G GPPG +G PGE+G G G G G Sbjct: 211 TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270 Query: 1835 LPGPPGPQGESRTGPPGSTGSRGPPGPP--GRPGNSGIRGPPGPPG 1878 PG PG G G PG+ G GPPGPP G+PG G++G GP G Sbjct: 271 APGQPGIPGTK--GLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAG 314 Score = 186 bits (473), Expect = 1e-46 Identities = 123/318 (38%), Positives = 142/318 (44%), Gaps = 68/318 (21%) Query: 1578 TQDSVGPPGPPGPA-----GGPGAKGPRGERGISGAIGPPGPRGDIGP------PGPQGP 1626 T+ G PG GP G PG G +GERG +G G PG +G+ GP PG GP Sbjct: 280 TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGP 339 Query: 1627 P---GPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF 1679 P GPQGP G+ +PG +G G G AG PG G G+PG G PG G PG G Sbjct: 340 PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP 399 Query: 1680 TGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM 1739 G G GP+G PG G PG PG GP+G G PG +G GP G G G RG I Sbjct: 400 KGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI----- 454 Query: 1740 MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGG 1799 GPPG PG PGS G G PGP G Sbjct: 455 --------------------------------------GPPGIPGFPGSKGDPGSPGPPG 476 Query: 1800 RPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPP 1859 G T G+ GP G G PG +G +G G G PGPPGP G++ P G + P Sbjct: 477 PAGI-ATKGLNGPTGPPGPPGPRGH--SGEPGLPGPPGPPGPPGQA-VMPEGFIKAGQRP 532 Query: 1860 GPPGRP---GNSGIRGPP 1874 G P N G+ G P Sbjct: 533 SLSGTPLVSANQGVTGMP 550 Score = 136 bits (342), Expect = 2e-31 Identities = 90/258 (34%), Positives = 103/258 (39%), Gaps = 59/258 (22%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P P + GP G GPAG G G +GERG G+ G PG G G GP+G PG Sbjct: 345 PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG 404 Query: 1629 PQGPNG-------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 1681 GP G +PG G G KG G G G G PG+PG GP+GPPG GF G Sbjct: 405 LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG 464 Query: 1682 KDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 1741 G G GPPGP G + G+ GP+G PG PG G G GL G G Sbjct: 465 SKGDPGSPGPPGPAGI-ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPG------------ 511 Query: 1742 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 1801 PPGPPG + G G RP Sbjct: 512 -------------------------------------PPGPPGQ--AVMPEGFIKAGQRP 532 Query: 1802 GFPGTPGMQGPPGERGLP 1819 GTP + G G+P Sbjct: 533 SLSGTPLVSANQGVTGMP 550 Score = 133 bits (334), Expect = 2e-30 Identities = 92/216 (42%), Positives = 106/216 (49%), Gaps = 27/216 (12%) Query: 1679 FTGKDGAMGPRGPPGPPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIA 1735 +T K + RG G PG PG G GPSG PGKPG +G PG G G G G Sbjct: 46 YTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGP-- 102 Query: 1736 SQNMMRAVARQVCEQLIS--GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA--GA 1791 AV + L G+ + + P R PGPPG PGP G + G Sbjct: 103 -----SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGK 157 Query: 1792 RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGS---SGPRGLPGPPGPQGESRTG 1848 G+ GP G PG G PG +G PG G+ G+KGE G G+ G RGLPGP GP G S G Sbjct: 158 PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPS--G 215 Query: 1849 PPGSTGSRGPPGPPGRPGNSGIR------GPPGPPG 1878 PPG G RG G PG+PG G R GP GPPG Sbjct: 216 PPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250 Score = 42.0 bits (97), Expect = 0.006 Identities = 17/29 (58%), Positives = 19/29 (65%) Query: 1851 GSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879 G G+ GPPGP G G+ G GPPG PGY Sbjct: 57 GEQGTPGPPGPAGPRGHPGPSGPPGKPGY 85 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 253 bits (647), Expect = 1e-66 Identities = 148/337 (43%), Positives = 175/337 (51%), Gaps = 40/337 (11%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGER---GISGAIGPP------------- 1612 P P + VGPPGP G AG GA G RGE G +G GPP Sbjct: 793 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852 Query: 1613 --GPRGDIGPPGPQGP---PGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPG 1666 G +GD G PGPQGP PGPQGP G++ P G +G QG G G PG GR G PG G Sbjct: 853 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 912 Query: 1667 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 1726 PGP GPPG +GKDG G RG GPPG G PG+ GP+G PG+ G+ G GPSG +G Sbjct: 913 NPGPPGPPGP---SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969 Query: 1727 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 1786 G +G +A Q + + Q E+ G P+ + PG G GPP Sbjct: 970 PPGPQG-LAGQRGIVGLPGQRGERGFPGLPG---------PSGEPGKQGAPGASGDRGPP 1019 Query: 1787 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES 1845 G G G GP G PG G+PG GPPG G G KG+RG TG+ G G PGPPG G + Sbjct: 1020 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1079 Query: 1846 ----RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 + G G G++GP GP G G GI+GP GP G Sbjct: 1080 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116 Score = 248 bits (634), Expect = 3e-65 Identities = 146/335 (43%), Positives = 166/335 (49%), Gaps = 60/335 (17%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GPPGPPGP+G G KG RG+ G G G PG +G GPPG +G PG GP+G G G Sbjct: 915 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE--GPPG 972 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 1702 QG+ G G GLPG+ G G PG PGP G PG +G GA G RGPPGP G PG G Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---APGASGDRGPPGPVGPPGLTG 1029 Query: 1703 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 1762 G G+ G PG G PG G G KGDRG+ + A Sbjct: 1030 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-------------------- 1069 Query: 1763 LNQIPNDYQSSRNQPGPPGPPGPPG---------SAGARGEPGPGGRPGFPGTPGMQGPP 1813 PGPPG PGP G AGA+G GP G G G G QGP Sbjct: 1070 --------------PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1115 Query: 1814 GERGLPGEKGERGT----GSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPGNS 1868 G++G GE GERG G +G +GLPGPPGP G+ +GP G +G RGPPGP G G Sbjct: 1116 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1175 Query: 1869 GIRG------PPGPPGYCDSSQCASIPYNGQGYPG 1897 G G PPGP G + A P N G PG Sbjct: 1176 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG 1209 Score = 248 bits (633), Expect = 4e-65 Identities = 150/360 (41%), Positives = 177/360 (49%), Gaps = 70/360 (19%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP----------------- 1621 Q VGP G PG G PG GP+G RG G +G PGP+G G P Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631 Query: 1622 -------GPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEP---------GLPGRTGT 1661 G GPPGP GP G PG G QG+ G G P G+PG G Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691 Query: 1662 PGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP---GKPGDHGR 1718 PGL GP G G PG+RG G G GPRG PG PG+ G G +GP+G P G PG G Sbjct: 692 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751 Query: 1719 P---GPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 1775 P G +G+ G KGDRGD+ + A + L +G + P + Sbjct: 752 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIG---------PPGPAGANG 801 Query: 1776 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TG 1828 + G GPPGP GSAGARG PG G G PG G GPPG G PG KGE+G G Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861 Query: 1829 SSGPRGLPGPPGPQGESR-TGPPGSTGSRGPPGPP---------GRPGNSGIRGPPGPPG 1878 + GP+G G PGPQG + TGP G+ G++GPPG G PG++G GPPGPPG Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921 Score = 243 bits (619), Expect = 2e-63 Identities = 172/477 (36%), Positives = 204/477 (42%), Gaps = 122/477 (25%) Query: 1508 KDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGK 1567 +D++EAG+ DG K + + ++C + + C P Sbjct: 26 QDVQEAGSCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGEC 85 Query: 1568 CPAFPNSCTCT----------------QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP 1611 CP P +D VGP GPPGP G G +GPRG+RG G G Sbjct: 86 CPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145 Query: 1612 PGPRG---------DIGPPGPQGPPGP---------------------------QGPNG- 1634 PGPRG + GPPGP GPPGP QGP G Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP 205 Query: 1635 ---------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA 1685 PG QG QG G+ GEPG+ G G G PGPPG PGD G GK G Sbjct: 206 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK---PGDDGEAGKPGK 262 Query: 1686 MGPRGPPGP------PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM 1739 G RGPPGP PG+PG PGV G G PG G G G G+KGE G G+ S Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322 Query: 1740 MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR---NQPGPPGPPGP---------PG 1787 M + + G+ R P +R QPGP GPPGP PG Sbjct: 323 MG-------PRGLPGERGRTG------PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 369 Query: 1788 SAGARGEPGPGGR---------PGFPGTPGMQGP------PGERGLPGEKGERGT-GSSG 1831 + GA+GE GP G G PGTPG GP PG G+PG KG G G +G Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 429 Query: 1832 PRGLP---GPPGPQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G P GPPGPQG + +TG PG G +G GP G PG +G +G PGP G Sbjct: 430 APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 486 Score = 242 bits (617), Expect = 3e-63 Identities = 146/338 (43%), Positives = 167/338 (49%), Gaps = 53/338 (15%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 1638 Q G PGP GP G G KG RG +G GA G PG G +GPPG G PGP GP P Sbjct: 866 QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-----P 920 Query: 1639 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------- 1691 G G+ G KG G+ G PGR G PGL GP GP G G+ G G GA GP GP Sbjct: 921 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 980 Query: 1692 -----PGPPGSPGSPGVTGPSGKPGK------PGDHGRPGPSGLKGEKGDRGDIASQNMM 1740 PG G G PG+ GPSG+PGK GD G PGP G G G G+ + Sbjct: 981 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 1040 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP------------GS 1788 A G R + + PG PGPPG P G Sbjct: 1041 GA----------DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090 Query: 1789 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG- 1843 AGA+G GP G G G G QGP G++G GE GERG G +G +GLPGPPGP G Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1150 Query: 1844 ESRTGPPGSTGSRGPP---GPPGRPGNSGIRGPPGPPG 1878 + +GP G +G RGPP GP G+ G +GI GP GPPG Sbjct: 1151 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188 Score = 240 bits (612), Expect = 1e-62 Identities = 148/353 (41%), Positives = 172/353 (48%), Gaps = 39/353 (11%) Query: 1583 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 1635 GPPGP GPAGGPG A G +GE G +GA GP G +G G PG G PGP G +G Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGKDGAMGPR 1689 IPG +G G G AG PG PG G PG G GP+GP PG GF G+ G G Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473 Query: 1690 GPPGPPGSP------------GSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGD- 1733 GP GP G+P G PG GP G PG+ PG+ G PG GL G KG G+ Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 533 Query: 1734 ----IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA 1789 +A + E + G + + P PG G PGPPG Sbjct: 534 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593 Query: 1790 GARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE- 1844 GARG+PG G PG G G G GE+GLPG G RG G +G G PGP GP GE Sbjct: 594 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653 Query: 1845 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG +G +G PGPPG PG G G G PG + P +G+PG Sbjct: 654 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG-PRGERGFPG 705 Score = 240 bits (612), Expect = 1e-62 Identities = 153/397 (38%), Positives = 178/397 (44%), Gaps = 94/397 (23%) Query: 1583 GPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 G PG G G PGA G RG + G +GA GPPGP G G G QG PGP G GL PG Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--PG 669 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 1699 G G G G+ G+PG G PGL GP G G PG+RG G G GPRG PG PG+ G Sbjct: 670 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729 Query: 1700 SPGVTGPSGKPGK---PGDHGRPGP---SGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 1753 G +GP+G PG PG G PG +G+ G KGDRGD+ + A + L + Sbjct: 730 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-T 788 Query: 1754 GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP 1813 G + P + + G GPPGP GSAGARG PG G G PG G GPP Sbjct: 789 GPIG---------PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839 Query: 1814 GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES--------------------- 1845 G G PG KGE+G G+ GP+G G PGPQG + Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899 Query: 1846 ----RTGPPGSTGSRGPPGPPGRPGN---------------------------------- 1867 R GPPGS G+ GPPGPPG G Sbjct: 900 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959 Query: 1868 -----SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 1897 SG GPPGP G +P +G+PG Sbjct: 960 GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996 Score = 240 bits (612), Expect = 1e-62 Identities = 135/301 (44%), Positives = 149/301 (49%), Gaps = 56/301 (18%) Query: 1583 GPPGPPGPAGGPGAKG---PRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 GP GPPGPAG G KG P G G +GA G PG RG+ GPPGP G GP PG Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------PG 840 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 1699 G+ G KG+ GE G G G PG GP G GP G G TG GA G +GPPG G PG Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900 Query: 1700 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 1759 + G GP G G PG G PGPSG G KG RGD Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-------------------------- 934 Query: 1760 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 1819 GPPG G PG G G PG G PG G G +GPPG +GL Sbjct: 935 -----------------SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 977 Query: 1820 GEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 1877 G++G G G G RG PG PGP GE + G PG++G RGPPGP G PG +G G PG Sbjct: 978 GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 1037 Query: 1878 G 1878 G Sbjct: 1038 G 1038 Score = 235 bits (599), Expect = 4e-61 Identities = 143/336 (42%), Positives = 167/336 (49%), Gaps = 35/336 (10%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGP---------RGDIG 1619 P P T G G PG AG G +GP+GE G +G G PGP RG+ G Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498 Query: 1620 PPGPQGPPGPQG-PNGLSIPGEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGPMGPPG 1675 GP GPPG +G P PG+ G G KG GE GL G G G PG PG G PG Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558 Query: 1676 DRGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 1732 RG TG+ G GP+G GP G+PG PG GP G G+PG G PGP G GE G G Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618 Query: 1733 D--IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PG 1784 + + +R + + E +G P R + G PGP PG Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPG---------PAGPAGERGEQGAPGPSGFQGLPG 669 Query: 1785 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG 1843 PPG G G+PG G PG G PG+ GP GERG PGE+G G G GPRGLPG PG G Sbjct: 670 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729 Query: 1844 -ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 + +GP G G++GPPG G PG G G GP G Sbjct: 730 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765 Score = 159 bits (402), Expect = 2e-38 Identities = 97/238 (40%), Positives = 114/238 (47%), Gaps = 35/238 (14%) Query: 1583 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 G PG PGP+G PG A G G+RG G +GPPG G G PG +G PG GP PG Sbjct: 993 GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PG 1047 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 1699 G G+KGD GE G G G PG PG PGP GP G +G G+ GA GP GP GP G+ G Sbjct: 1048 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1107 Query: 1700 SPGVTGPSGKPGKPGDHGR------------------PGPSGLKGEKGDRGDIASQNMMR 1741 G GP G G+ G+ G PGPSG +G G G + Sbjct: 1108 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1167 Query: 1742 AVARQVCEQLISGQMNRFNQMLNQI-PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 1798 V SG+ + N + I P + + GP GPPG PG G G PGPG Sbjct: 1168 PVGP-------SGK-DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1217 Score = 112 bits (281), Expect = 3e-24 Identities = 59/134 (44%), Positives = 67/134 (50%), Gaps = 17/134 (12%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P+ P Q GP G G AG PG +G +G RG +G G PGP G G G GP G Sbjct: 1099 PSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG 1158 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 P GP G PG G +G G G PGP+GPPG RG +G+ G GP Sbjct: 1159 PSGPR-----------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201 Query: 1689 RGPPGPPGSPGSPG 1702 G PGPPG PG PG Sbjct: 1202 PGNPGPPGPPGPPG 1215 Score = 87.4 bits (215), Expect = 1e-16 Identities = 53/115 (46%), Positives = 56/115 (48%), Gaps = 22/115 (19%) Query: 1576 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 1635 T Q GPPGP G G G GP G RG G +GP G G G PGP GPPGP Sbjct: 1136 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP------ 1189 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPR 1689 +GR G G AG P G PG PGPPGP GP D F G +GPR Sbjct: 1190 -----RGRSGETGPAGPP------GNPGPPGPPGPPGPGIDMSAFAG----LGPR 1229 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 253 bits (647), Expect = 1e-66 Identities = 148/337 (43%), Positives = 175/337 (51%), Gaps = 40/337 (11%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGER---GISGAIGPP------------- 1612 P P + VGPPGP G AG GA G RGE G +G GPP Sbjct: 724 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 783 Query: 1613 --GPRGDIGPPGPQGP---PGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPG 1666 G +GD G PGPQGP PGPQGP G++ P G +G QG G G PG GR G PG G Sbjct: 784 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 843 Query: 1667 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 1726 PGP GPPG +GKDG G RG GPPG G PG+ GP+G PG+ G+ G GPSG +G Sbjct: 844 NPGPPGPPGP---SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900 Query: 1727 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 1786 G +G +A Q + + Q E+ G P+ + PG G GPP Sbjct: 901 PPGPQG-LAGQRGIVGLPGQRGERGFPGLPG---------PSGEPGKQGAPGASGDRGPP 950 Query: 1787 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES 1845 G G G GP G PG G+PG GPPG G G KG+RG TG+ G G PGPPG G + Sbjct: 951 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1010 Query: 1846 ----RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 + G G G++GP GP G G GI+GP GP G Sbjct: 1011 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047 Score = 248 bits (634), Expect = 3e-65 Identities = 146/335 (43%), Positives = 166/335 (49%), Gaps = 60/335 (17%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GPPGPPGP+G G KG RG+ G G G PG +G GPPG +G PG GP+G G G Sbjct: 846 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE--GPPG 903 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 1702 QG+ G G GLPG+ G G PG PGP G PG +G GA G RGPPGP G PG G Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---APGASGDRGPPGPVGPPGLTG 960 Query: 1703 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 1762 G G+ G PG G PG G G KGDRG+ + A Sbjct: 961 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-------------------- 1000 Query: 1763 LNQIPNDYQSSRNQPGPPGPPGPPG---------SAGARGEPGPGGRPGFPGTPGMQGPP 1813 PGPPG PGP G AGA+G GP G G G G QGP Sbjct: 1001 --------------PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1046 Query: 1814 GERGLPGEKGERGT----GSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPGNS 1868 G++G GE GERG G +G +GLPGPPGP G+ +GP G +G RGPPGP G G Sbjct: 1047 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1106 Query: 1869 GIRG------PPGPPGYCDSSQCASIPYNGQGYPG 1897 G G PPGP G + A P N G PG Sbjct: 1107 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG 1140 Score = 248 bits (633), Expect = 4e-65 Identities = 150/360 (41%), Positives = 177/360 (49%), Gaps = 70/360 (19%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP----------------- 1621 Q VGP G PG G PG GP+G RG G +G PGP+G G P Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562 Query: 1622 -------GPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEP---------GLPGRTGT 1661 G GPPGP GP G PG G QG+ G G P G+PG G Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622 Query: 1662 PGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP---GKPGDHGR 1718 PGL GP G G PG+RG G G GPRG PG PG+ G G +GP+G P G PG G Sbjct: 623 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682 Query: 1719 P---GPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 1775 P G +G+ G KGDRGD+ + A + L +G + P + Sbjct: 683 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIG---------PPGPAGANG 732 Query: 1776 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TG 1828 + G GPPGP GSAGARG PG G G PG G GPPG G PG KGE+G G Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792 Query: 1829 SSGPRGLPGPPGPQGESR-TGPPGSTGSRGPPGPP---------GRPGNSGIRGPPGPPG 1878 + GP+G G PGPQG + TGP G+ G++GPPG G PG++G GPPGPPG Sbjct: 793 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852 Score = 242 bits (617), Expect = 3e-63 Identities = 146/338 (43%), Positives = 167/338 (49%), Gaps = 53/338 (15%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 1638 Q G PGP GP G G KG RG +G GA G PG G +GPPG G PGP GP P Sbjct: 797 QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-----P 851 Query: 1639 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------- 1691 G G+ G KG G+ G PGR G PGL GP GP G G+ G G GA GP GP Sbjct: 852 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 911 Query: 1692 -----PGPPGSPGSPGVTGPSGKPGK------PGDHGRPGPSGLKGEKGDRGDIASQNMM 1740 PG G G PG+ GPSG+PGK GD G PGP G G G G+ + Sbjct: 912 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 971 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP------------GS 1788 A G R + + PG PGPPG P G Sbjct: 972 GA----------DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021 Query: 1789 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG- 1843 AGA+G GP G G G G QGP G++G GE GERG G +G +GLPGPPGP G Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1081 Query: 1844 ESRTGPPGSTGSRGPP---GPPGRPGNSGIRGPPGPPG 1878 + +GP G +G RGPP GP G+ G +GI GP GPPG Sbjct: 1082 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119 Score = 240 bits (613), Expect = 8e-63 Identities = 158/387 (40%), Positives = 180/387 (46%), Gaps = 100/387 (25%) Query: 1579 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIG------------------PPGPRGDIGP 1620 +D VGP GPPGP G G +GPRG+RG G G PPGP G GP Sbjct: 44 KDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP 103 Query: 1621 PG------------------------PQGPPGPQGPNGLSIP-GEQGRQGMKGDAGEPGL 1655 PG QGP GP GP G P G G QG +G+ GEPG Sbjct: 104 PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGE 163 Query: 1656 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP------PGSPGSPGVTGPSGK 1709 PG +G G GPPGP G PGD G GK G G RGPPGP PG+PG PGV G G Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 223 Query: 1710 PGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPND 1769 PG G G G G+KGE G G+ S M + + G+ R P Sbjct: 224 PGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-------PRGLPGERGRTG------PAG 270 Query: 1770 YQSSR---NQPGPPGPPGP---------PGSAGARGEPGPGGR---------PGFPGTPG 1808 +R QPGP GPPGP PG+ GA+GE GP G G PGTPG Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330 Query: 1809 MQGP------PGERGLPGEKGERGT-GSSGPRGLP---GPPGPQG-------ESRTGPPG 1851 GP PG G+PG KG G G +G G P GPPGPQG + +TG PG Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390 Query: 1852 STGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G +G GP G PG +G +G PGP G Sbjct: 391 IAGFKGEQGPKGEPGPAGPQGAPGPAG 417 Score = 240 bits (612), Expect = 1e-62 Identities = 148/353 (41%), Positives = 172/353 (48%), Gaps = 39/353 (11%) Query: 1583 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 1635 GPPGP GPAGGPG A G +GE G +GA GP G +G G PG G PGP G +G Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGKDGAMGPR 1689 IPG +G G G AG PG PG G PG G GP+GP PG GF G+ G G Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404 Query: 1690 GPPGPPGSP------------GSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGD- 1733 GP GP G+P G PG GP G PG+ PG+ G PG GL G KG G+ Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 464 Query: 1734 ----IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA 1789 +A + E + G + + P PG G PGPPG Sbjct: 465 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 524 Query: 1790 GARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE- 1844 GARG+PG G PG G G G GE+GLPG G RG G +G G PGP GP GE Sbjct: 525 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584 Query: 1845 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 G PG +G +G PGPPG PG G G G PG + P +G+PG Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG-PRGERGFPG 636 Score = 240 bits (612), Expect = 1e-62 Identities = 153/397 (38%), Positives = 178/397 (44%), Gaps = 94/397 (23%) Query: 1583 GPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 G PG G G PGA G RG + G +GA GPPGP G G G QG PGP G GL PG Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--PG 600 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 1699 G G G G+ G+PG G PGL GP G G PG+RG G G GPRG PG PG+ G Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660 Query: 1700 SPGVTGPSGKPGK---PGDHGRPGP---SGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 1753 G +GP+G PG PG G PG +G+ G KGDRGD+ + A + L + Sbjct: 661 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-T 719 Query: 1754 GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP 1813 G + P + + G GPPGP GSAGARG PG G G PG G GPP Sbjct: 720 GPIG---------PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770 Query: 1814 GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES--------------------- 1845 G G PG KGE+G G+ GP+G G PGPQG + Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830 Query: 1846 ----RTGPPGSTGSRGPPGPPGRPGN---------------------------------- 1867 R GPPGS G+ GPPGPPG G Sbjct: 831 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890 Query: 1868 -----SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 1897 SG GPPGP G +P +G+PG Sbjct: 891 GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927 Score = 240 bits (612), Expect = 1e-62 Identities = 135/301 (44%), Positives = 149/301 (49%), Gaps = 56/301 (18%) Query: 1583 GPPGPPGPAGGPGAKG---PRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 GP GPPGPAG G KG P G G +GA G PG RG+ GPPGP G GP PG Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------PG 771 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 1699 G+ G KG+ GE G G G PG GP G GP G G TG GA G +GPPG G PG Sbjct: 772 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831 Query: 1700 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 1759 + G GP G G PG G PGPSG G KG RGD Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-------------------------- 865 Query: 1760 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 1819 GPPG G PG G G PG G PG G G +GPPG +GL Sbjct: 866 -----------------SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 908 Query: 1820 GEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 1877 G++G G G G RG PG PGP GE + G PG++G RGPPGP G PG +G G PG Sbjct: 909 GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 968 Query: 1878 G 1878 G Sbjct: 969 G 969 Score = 235 bits (599), Expect = 4e-61 Identities = 143/336 (42%), Positives = 167/336 (49%), Gaps = 35/336 (10%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGP---------RGDIG 1619 P P T G G PG AG G +GP+GE G +G G PGP RG+ G Sbjct: 370 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 429 Query: 1620 PPGPQGPPGPQG-PNGLSIPGEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGPMGPPG 1675 GP GPPG +G P PG+ G G KG GE GL G G G PG PG G PG Sbjct: 430 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489 Query: 1676 DRGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 1732 RG TG+ G GP+G GP G+PG PG GP G G+PG G PGP G GE G G Sbjct: 490 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549 Query: 1733 D--IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PG 1784 + + +R + + E +G P R + G PGP PG Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGPPG---------PAGPAGERGEQGAPGPSGFQGLPG 600 Query: 1785 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG 1843 PPG G G+PG G PG G PG+ GP GERG PGE+G G G GPRGLPG PG G Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660 Query: 1844 -ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 + +GP G G++GPPG G PG G G GP G Sbjct: 661 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696 Score = 234 bits (597), Expect = 6e-61 Identities = 150/382 (39%), Positives = 172/382 (45%), Gaps = 104/382 (27%) Query: 1582 VGPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGP--------------- 1623 +GP GPPGPAG PG +G +G E G G GP GPRG GPPG Sbjct: 137 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196 Query: 1624 QGPPGPQGPNGL----SIPGEQGRQ------GMKGDAGEPGLPGRTGTPGLPGPPGPMGP 1673 +GPPGPQG G +PG +G + G KG+AG PG+ G +G+PG G PGPMGP Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256 Query: 1674 ---PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGD 1730 PG+RG TG GA G RG G PG G PG GP+G PG PG G G +G G +G Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG- 315 Query: 1731 RGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP----- 1785 P Q R +PG PG PGP Sbjct: 316 ------------------------------------PEGAQGPRGEPGTPGSPGPAGASG 339 Query: 1786 -------PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSG 1831 PG+ G+ G PG G PGFPG G GP G G G KG+ G G G Sbjct: 340 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG 399 Query: 1832 PRGLPGPPGPQG-------ESRTGPPGSTGSRGPPGPPGR---------PGNSGIRGPPG 1875 P+G PGP GPQG E + G G G GP GPPG PG G+ GP G Sbjct: 400 PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG 459 Query: 1876 PPGYCDSSQCASIPYNGQGYPG 1897 PG S A P G PG Sbjct: 460 APGERGPSGLAG-PKGANGDPG 480 Score = 220 bits (560), Expect = 1e-56 Identities = 145/340 (42%), Positives = 163/340 (47%), Gaps = 56/340 (16%) Query: 1583 GPPGP------PGPAGGPGAKGPRGERGISGA---IGPPGPRGDIGPP------GPQGPP 1627 GPPGP PG G PG KG RG G+ GA G PG +G+ G P GP GP Sbjct: 198 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 257 Query: 1628 GPQGPNGLSIP----GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 1683 G G G + P G +G G G AG PG G G PG PG PG G G G G + Sbjct: 258 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317 Query: 1684 GAMGPRGPPGPPGSPGSPGVT---GPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 1740 GA GPRG PG PGSPG G + G G PG G G PG +G G G RG Q Sbjct: 318 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377 Query: 1741 RAVA--RQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA------GAR 1792 + Q E I+G Q + +PGP GP G PG A GAR Sbjct: 378 GPLGPKGQTGEPGIAGFKGE------------QGPKGEPGPAGPQGAPGPAGEEGKRGAR 425 Query: 1793 GEP---GPGGRPGFPGTPGMQGPPGERGLPGEK---GERG-TGSSGPRGLPGPPGPQGE- 1844 GEP GP G PG G PG +G PG+ GL G K GERG +G +GP+G G PG GE Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485 Query: 1845 ------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 TG PG G +G GP G PG G GPPGP G Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 525 Score = 173 bits (438), Expect = 2e-42 Identities = 118/309 (38%), Positives = 131/309 (42%), Gaps = 95/309 (30%) Query: 1635 LSIPGEQGRQ-GMKGDAGEPG----LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 1689 L G+ RQ G KG GEPG + G G PG GP G GP GDRG G+ GA GPR Sbjct: 21 LRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 80 Query: 1690 G------PPGPPGSPGSP---------------------------------GVTGPSGKP 1710 G PG PG PG P G GP G Sbjct: 81 GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140 Query: 1711 GKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY 1770 G PG G PGP G +G G+ G E +SG M Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPG----------------EPGVSGPM-------------- 170 Query: 1771 QSSRNQPGPPGPP------GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGE 1824 R PGPPG P G PG AG RG PGP G GFPGTPG+ G G RG PG G Sbjct: 171 -GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA 229 Query: 1825 RG----------TGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGPPGPPGRPGNSGI 1870 +G +GS G G PGP GP+G RTGP G+ G+RG G PG G G Sbjct: 230 KGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP 289 Query: 1871 RGPPGPPGY 1879 GP G PG+ Sbjct: 290 VGPAGGPGF 298 Score = 159 bits (402), Expect = 2e-38 Identities = 97/238 (40%), Positives = 114/238 (47%), Gaps = 35/238 (14%) Query: 1583 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 1639 G PG PGP+G PG A G G+RG G +GPPG G G PG +G PG GP PG Sbjct: 924 GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PG 978 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 1699 G G+KGD GE G G G PG PG PGP GP G +G G+ GA GP GP GP G+ G Sbjct: 979 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1038 Query: 1700 SPGVTGPSGKPGKPGDHGR------------------PGPSGLKGEKGDRGDIASQNMMR 1741 G GP G G+ G+ G PGPSG +G G G + Sbjct: 1039 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1098 Query: 1742 AVARQVCEQLISGQMNRFNQMLNQI-PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 1798 V SG+ + N + I P + + GP GPPG PG G G PGPG Sbjct: 1099 PVGP-------SGK-DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1148 Score = 112 bits (281), Expect = 3e-24 Identities = 59/134 (44%), Positives = 67/134 (50%), Gaps = 17/134 (12%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P+ P Q GP G G AG PG +G +G RG +G G PGP G G G GP G Sbjct: 1030 PSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG 1089 Query: 1629 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 1688 P GP G PG G +G G G PGP+GPPG RG +G+ G GP Sbjct: 1090 PSGPR-----------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132 Query: 1689 RGPPGPPGSPGSPG 1702 G PGPPG PG PG Sbjct: 1133 PGNPGPPGPPGPPG 1146 Score = 111 bits (277), Expect = 8e-24 Identities = 83/238 (34%), Positives = 91/238 (38%), Gaps = 94/238 (39%) Query: 1715 DHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 1774 D +PGP G KGE GD DI Sbjct: 27 DVRQPGPKGQKGEPGDIKDIVGPK------------------------------------ 50 Query: 1775 NQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPGTPGMQGPPGERGLPGEKGER 1825 GPPGP GP G G RG+ PGP GR G PGTPG GPPG G PG G Sbjct: 51 ---GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107 Query: 1826 GT-------------------------GSSGPRGLPGP---PGPQG-ESRTGPPGS---- 1852 G G GPRG PGP PGPQG + G PG Sbjct: 108 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167 Query: 1853 --TGSRGPPGPPGRPGN---------SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 1897 G RGPPGPPG+PG+ +G RGPPGP G +P +GYPG Sbjct: 168 GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPG 225 Score = 87.4 bits (215), Expect = 1e-16 Identities = 53/115 (46%), Positives = 56/115 (48%), Gaps = 22/115 (19%) Query: 1576 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 1635 T Q GPPGP G G G GP G RG G +GP G G G PGP GPPGP Sbjct: 1067 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP------ 1120 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPR 1689 +GR G G AG P G PG PGPPGP GP D F G +GPR Sbjct: 1121 -----RGRSGETGPAGPP------GNPGPPGPPGPPGPGIDMSAFAG----LGPR 1160 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 253 bits (647), Expect = 1e-66 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 1628 GPPGPPG G GA GP+G+RG G GPPG P+GD+GP PGP GPPG Sbjct: 757 GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Query: 1629 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 1673 P GP G+ PG G G KGD G PGL PG G+PG+PG PGP+GP Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 1674 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 1721 PG G GK GA MGP GPPGP G PG GV G G G G G PGP Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 1722 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 1771 +G KG KG+ G + + L+ + + L I P YQ Sbjct: 937 TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 1772 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 1812 QPG PGPPGP G+ G G+PG PG G GFPG G++GP Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 1813 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 1865 PG GLPG+KG++G GLPG PGP+GE G PG GS G PG PG P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 1866 GNSGIRGPPGPPGY 1879 G G +G PG PG+ Sbjct: 1110 GTPGAKGQPGLPGF 1123 Score = 246 bits (629), Expect = 1e-64 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%) Query: 1582 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 1635 +GPPGPPGP +G PG KG G +G G GP G +G G PG GPPGP PN L Sbjct: 901 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Query: 1636 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 1674 IPG G +G +G G+PG PG +G PGLPGPPGP G P Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 1675 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 1723 GD GF G G GP GP G PG PGSPG+ G G G PG G PG G Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080 Query: 1724 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 1782 KGE G G + + +V L + L P PGPPGP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133 Query: 1783 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 1831 GPPG+ G GEPGP GG PG PG PG +G PG+ G+P GE G+ G G+ G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 1832 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 P GLPG G +G+ G PG+ G GP G PG G G++GPPGPPG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Score = 238 bits (608), Expect = 3e-62 Identities = 148/329 (44%), Positives = 170/329 (51%), Gaps = 25/329 (7%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQG 1625 P P + + G PG PGP GG PG GP GE+G G G PGP G G PG G Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Query: 1626 --PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 1683 PGP G GLS G++G G+ G G PGLPG G PG G PG GPPG G G Sbjct: 1189 FGNPGPPGLPGLS--GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP- 1245 Query: 1684 GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 GP+G PGP G PG PG TG G PG G G PG G+KGEKG+ G + Sbjct: 1246 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1305 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 1801 Q L Q N LN + D PG GP G PGSAG GEPG G P Sbjct: 1306 GDQGPPGL---QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1362 Query: 1802 GFPGTPG-------MQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGE-SRTGPPGS 1852 G PG PG ++G G G+PG+ G +G G GP+GLPGP GP G+ R G PG Sbjct: 1363 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF 1422 Query: 1853 TGS---RGPPGPPGRPGNSGIRGPPGPPG 1878 G+ +G PG PG+PG G+ GPPGP G Sbjct: 1423 DGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1451 Score = 237 bits (604), Expect = 9e-62 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 1636 +G PGPPGP G PG GP G G G IG GP G G PGP+G PGP GP GL Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764 Query: 1637 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 1679 PG +G G KGD G PG PGRTG GLPGP PGPMGPPG G Sbjct: 765 -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 1680 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 1716 G G G +G PGPP GSPG PG GP G PG PG Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883 Query: 1717 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 1774 G+ G SG G KG+ G + + + + G Q P + S+ Sbjct: 884 GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 1775 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 1832 +PG PGPPGP P G++GE G PG PG PG+ GP G +GLPG+ G+ G SG Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998 Query: 1833 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 1878 GLPGPPGP+G G PG G GPPG G PG G+ GPPGP G Sbjct: 999 PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048 Score = 236 bits (601), Expect = 2e-61 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%) Query: 1580 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 1634 D + PGPPGP G PG KG +GE+G+ G G G GPPG G PG GP G Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 1693 L PG++G +G G G GLPG G PG PG PG G PGD F G G G G PG Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 1694 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 1753 PG PG PG G G PG PG G PG KGE+G G+ + + Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617 Query: 1754 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 1801 G M F Q PG PG PGP PG G G PG G Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 1802 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 1855 G PG PG+ G PG G+PG KGE G G GP+G PG PGP G G PG G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735 Query: 1856 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GPPGPPG PG G + GPPGPPG + A P +G+PG Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781 Score = 234 bits (596), Expect = 8e-61 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%) Query: 1546 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 1605 CSP S+ C I + E P + G PG PGP G PG PRG++G Sbjct: 32 CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79 Query: 1606 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 1661 G GPPGP+G GPPG G PG G G+ PG QG G G GE G PG G Sbjct: 80 DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Query: 1662 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 1712 PGL GPPGP G PG +G G G G GPPG G PG G+ GP G PG Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 1713 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 1771 PG G PGP GL G KG+ G + Q Q Q G + ++ I ++Q Sbjct: 200 PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257 Query: 1772 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 1809 R PGPP GPPGPP G G +GEPG PG G+PG PG PG Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317 Query: 1810 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 1845 G PGE G GEKG++G TG GP GLPG PG +GE Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377 Query: 1846 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 1878 GPPG G GPPGPPG PG G +G GPPG Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415 Score = 231 bits (588), Expect = 7e-60 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GP G PG G PG +G G GI G IGPPGP G +GPPGP G PGP+G GL+ G +G Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227 Query: 1643 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 1685 +G +G G PG PG+ G GLPG GP GPPG RG G + G Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 1686 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 1745 G +G PG G PG G G G PG PGD G PG G GEKG +GD V Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 1746 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 1792 + + G+ L +P + Q PGPPG PPGPPG G R Sbjct: 348 RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 1793 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 1839 G+ G G PG PG PG+ G PG GLPG G G G GP G PG Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 1840 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 1882 G QGE +GPPG G G PGPPG G G +G G G Sbjct: 466 GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525 Query: 1883 SQCASIP--YNGQGYPGS 1898 IP G+PGS Sbjct: 526 KGLPGIPGAPGAPGFPGS 543 Score = 228 bits (582), Expect = 3e-59 Identities = 144/342 (42%), Positives = 167/342 (48%), Gaps = 32/342 (9%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 S+G PG PGP G PG G G GI G++G PG G G PG +G PG G G PG Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 1691 G +G+ G G PGLPG G G G PG GPPG++G G+DG GP G Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 1692 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 1749 PGPPG PG G G G PG PG+ G PGP G G G G + + Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL-- 1247 Query: 1750 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 1809 + G P +Q PGP GPPG PG+ G +GE G G+PG PG PG+ Sbjct: 1248 EGPKGNPGPQGPPGRPGPTGFQ---GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1304 Query: 1810 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 1861 QGPPG +G PG G G G G G+PG PG +G S GP G G GPPGP Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364 Query: 1862 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 1897 PG PG SG I+G GPPG + P QG PG Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406 Score = 223 bits (568), Expect = 1e-57 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 1640 G PG PGP G G G +GE+G +GA GP G G G PG G PG +G G L+ PG Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 MKGD GE G PG G PGLPG PG G PG G G+ G + +G GPPG+PG Sbjct: 556 -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610 Query: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 1754 PG+ G G G PG G PGP G KG +G G+ + Q + + G Sbjct: 611 PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669 Query: 1755 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 1801 R + +P D S+ +PG P G PGPPG G G PGP G P Sbjct: 670 NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727 Query: 1802 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 1843 G PG G++GPPG G PG KGE G G G RG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787 Query: 1844 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 1878 + GP G G G PGP G PG G++GPPGPPG Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828 Score = 219 bits (557), Expect = 3e-56 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 1636 G PG PGP G PG +GERG G G PG G+IGP GP G PPGP G G+ Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 1637 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 1684 PG+ G G KGD G+ PG PGR G GLPG PG G PG G G G Sbjct: 642 NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701 Query: 1685 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 1741 +G GPPGP G PG PG G G PG+ G G PGP G G KG+ G Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753 Query: 1742 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 1792 A+ + G F L + R PGPPGPPG P G G Sbjct: 754 ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 1793 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 1851 G+PGP G PG PG G+QGPPG G+PG G+ G G G +G PGPPG PG Sbjct: 805 GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857 Query: 1852 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 G RG PG PG PG G G PG PG +S G+PG+ Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894 Score = 218 bits (555), Expect = 4e-56 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%) Query: 1583 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 1628 GPPGPPG G PG KG +GE+G G G PG G+ G PG G PG Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 1629 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 1666 P GP GL IP G G G+ G+ GE G PG G PGLPG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386 Query: 1667 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 1708 PPG MGPPG GF G+ G G GPPG PG+PG PG GP+G Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446 Query: 1709 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 1763 +PG PG G PG GL+GE+G +GD C I ++ Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490 Query: 1764 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 1811 PG PG PG PG G+ G P GP G PG PG PG G Sbjct: 491 -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539 Query: 1812 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 1851 PG +G P G+KGE G+ G+ G GLPG PGP+GE P G Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595 Query: 1852 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 1879 T G RGPPG PG PG G GP GPPG+ Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625 Score = 209 bits (532), Expect = 2e-53 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 1599 P FP S D + PG G G PG GP Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597 Query: 1600 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 1652 +GERG G G PG G+IGP GP GPPGP G G+ PG+ G G KGD G+ Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 1653 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 1697 PG PGR G GLPG PG G PG G G G +G GPPGP G Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717 Query: 1698 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 1757 PG PG G G PG+ G G PGP G G KG+ G A+ + G Sbjct: 718 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766 Query: 1758 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 1808 F L + R PGPPGP PGP G G G+PGP G PG PG G Sbjct: 767 -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819 Query: 1809 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 1861 +QGPPG G+PG G+ G G G +G PGP PGP GE G PG+ G GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 1862 PGRPGNS------------GIRGPPGPPG 1878 PG PG + G+ GPPGPPG Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 208 bits (530), Expect = 4e-53 Identities = 125/300 (41%), Positives = 140/300 (46%), Gaps = 66/300 (22%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP--------PGPQGPPGPQGPNG 1634 G PG PG G PG KG G G G GPPGP G GP PGPQGPPG GP G Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTG 1267 Query: 1635 LS-IPGEQGRQGMKGDAG---EPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 1690 +PG +G G+ G+ G E G PG+ G PGLPG G GPPG +G G+ G G +G Sbjct: 1268 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1327 Query: 1691 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 1750 PG PG PG PG+ GPSG PG G G PG G G G G +++ Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK--------- 1378 Query: 1751 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 1810 G GPPG PG G +G PGP G G PG G Sbjct: 1379 ---------------------------GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPP 1411 Query: 1811 GPPGERGLPG------EKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPG 1863 G PG GLPG KG+ G G G RGL GPPGP G +GPPGPPG Sbjct: 1412 GDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD-----------GLQGPPGPPG 1460 Score = 204 bits (520), Expect = 5e-52 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%) Query: 1581 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 1631 ++GP GPPG P G G KG +G G G G PGP+GD G PG G PG G Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 1632 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 1669 GL +PG+ G G+ G GEPG+PG G PG+PGPPG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 1670 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 1710 P GPPG G G GA+GP+G G PG PG PG TG G P Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 1711 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 1767 G GD +G+PGP G G G I Q I G + + L+ IP Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842 Query: 1768 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 1825 + + PGPPG PGPPG G+ G PG G G PG+PG+ G G G PG KGE Sbjct: 843 GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898 Query: 1826 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 1878 G G PGPPGP G R+G PG G G G PG PG +G +G PGPPG Sbjct: 899 GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 1879 YCDSSQCASIPYNGQ-GYPG 1897 D + S G+ G PG Sbjct: 954 PMDPNLLGSKGEKGEPGLPG 973 Score = 139 bits (349), Expect = 3e-32 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G PG PG G PG KGP G + G+ GP G G IGPPGP G PGP G + + I G+ G Sbjct: 1327 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1382 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 1702 G+ G G GLPG G GLPGP GP G PG G G DGA G +G PG PG PG+ G Sbjct: 1383 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1442 Query: 1703 VTGPSGKPGKPGDHGRPGPSGL 1724 + GP G G G G PG S + Sbjct: 1443 LDGPPGPDGLQGPPGPPGTSSV 1464 Score = 105 bits (263), Expect = 3e-22 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 1777 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 1836 PGP GPPGP G G G PGP G G G PG+ G PG GLPG G G+ GP+G+P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122 Query: 1837 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 1886 G G +GE G PG G +GPPGPPG PG G + GP G PGY Sbjct: 123 GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182 Query: 1887 SIPYNGQGYPG 1897 +P G PG Sbjct: 183 GLP-GPTGIPG 192 Score = 90.9 bits (224), Expect = 1e-17 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Query: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 1843 G G G RG PG G PG PG PG +GPPG RG G+ G G GP+G+ GPPG G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99 Query: 1844 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879 T G PG G+ GP G PG G G RG PG PG+ Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Score = 75.1 bits (183), Expect = 6e-13 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%) Query: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 1833 G P A A PG + G G +G G GL G G G G GPR Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 1834 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 1893 G+PGPPGP+G GPPG G G PG PG PG+ G GP G PG C+ ++ + Sbjct: 81 GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131 Query: 1894 GYPGS 1898 G+PGS Sbjct: 132 GFPGS 136 Score = 60.8 bits (146), Expect = 1e-08 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 1636 GPPG PG G PG G G +G G G PG RG GPPGP QGPPGP G + ++ Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 253 bits (647), Expect = 1e-66 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 1628 GPPGPPG G GA GP+G+RG G GPPG P+GD+GP PGP GPPG Sbjct: 757 GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Query: 1629 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 1673 P GP G+ PG G G KGD G PGL PG G+PG+PG PGP+GP Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 1674 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 1721 PG G GK GA MGP GPPGP G PG GV G G G G G PGP Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 1722 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 1771 +G KG KG+ G + + L+ + + L I P YQ Sbjct: 937 TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 1772 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 1812 QPG PGPPGP G+ G G+PG PG G GFPG G++GP Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 1813 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 1865 PG GLPG+KG++G GLPG PGP+GE G PG GS G PG PG P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 1866 GNSGIRGPPGPPGY 1879 G G +G PG PG+ Sbjct: 1110 GTPGAKGQPGLPGF 1123 Score = 246 bits (629), Expect = 1e-64 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%) Query: 1582 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 1635 +GPPGPPGP +G PG KG G +G G GP G +G G PG GPPGP PN L Sbjct: 901 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Query: 1636 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 1674 IPG G +G +G G+PG PG +G PGLPGPPGP G P Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 1675 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 1723 GD GF G G GP GP G PG PGSPG+ G G G PG G PG G Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080 Query: 1724 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 1782 KGE G G + + +V L + L P PGPPGP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133 Query: 1783 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 1831 GPPG+ G GEPGP GG PG PG PG +G PG+ G+P GE G+ G G+ G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 1832 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 P GLPG G +G+ G PG+ G GP G PG G G++GPPGPPG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Score = 239 bits (611), Expect = 1e-62 Identities = 156/372 (41%), Positives = 186/372 (50%), Gaps = 56/372 (15%) Query: 1559 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 1618 +P + E P +P + + SVG PG PG G PGAKG G G G GPPGP+G Sbjct: 1078 LPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136 Query: 1619 GPPGPQGPPGPQGPNG-------LSIPGEQGRQGM---------KGDAGEPG-------- 1654 GPPG G PG GP G PGE+G+ G KG+ G+PG Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 1655 ---LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP--------GSPGV 1703 L G+ G GLPG PG G PG +G G G G +GPPGPPGSP G+PG Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256 Query: 1704 TGPSGKPGKPGDH---GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 1760 GP G+PG PG G PG G+KGEKG+ G + Q L Q N Sbjct: 1257 QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL---QGNPGR 1313 Query: 1761 QMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG-------MQG 1811 LN + D PG GP G PGSAG GEPG G PG PG PG ++G Sbjct: 1314 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1373 Query: 1812 PPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPP---GSTGSRGPPGPPGRPG 1866 G G+PG+ G +G G GP+GLPGP GP G+ R G P G+ G +G PG PG+PG Sbjct: 1374 DAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG 1433 Query: 1867 NSGIRGPPGPPG 1878 G+ GPPGP G Sbjct: 1434 TRGLDGPPGPDG 1445 Score = 237 bits (604), Expect = 9e-62 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 1636 +G PGPPGP G PG GP G G G IG GP G G PGP+G PGP GP GL Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764 Query: 1637 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 1679 PG +G G KGD G PG PGRTG GLPGP PGPMGPPG G Sbjct: 765 -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 1680 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 1716 G G G +G PGPP GSPG PG GP G PG PG Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883 Query: 1717 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 1774 G+ G SG G KG+ G + + + + G Q P + S+ Sbjct: 884 GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 1775 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 1832 +PG PGPPGP P G++GE G PG PG PG+ GP G +GLPG+ G+ G SG Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998 Query: 1833 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 1878 GLPGPPGP+G G PG G GPPG G PG G+ GPPGP G Sbjct: 999 PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048 Score = 236 bits (601), Expect = 2e-61 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%) Query: 1580 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 1634 D + PGPPGP G PG KG +GE+G+ G G G GPPG G PG GP G Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 1693 L PG++G +G G G GLPG G PG PG PG G PGD F G G G G PG Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 1694 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 1753 PG PG PG G G PG PG G PG KGE+G G+ + + Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617 Query: 1754 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 1801 G M F Q PG PG PGP PG G G PG G Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 1802 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 1855 G PG PG+ G PG G+PG KGE G G GP+G PG PGP G G PG G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735 Query: 1856 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GPPGPPG PG G + GPPGPPG + A P +G+PG Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781 Score = 234 bits (596), Expect = 8e-61 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%) Query: 1546 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 1605 CSP S+ C I + E P + G PG PGP G PG PRG++G Sbjct: 32 CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79 Query: 1606 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 1661 G GPPGP+G GPPG G PG G G+ PG QG G G GE G PG G Sbjct: 80 DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Query: 1662 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 1712 PGL GPPGP G PG +G G G G GPPG G PG G+ GP G PG Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 1713 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 1771 PG G PGP GL G KG+ G + Q Q Q G + ++ I ++Q Sbjct: 200 PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257 Query: 1772 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 1809 R PGPP GPPGPP G G +GEPG PG G+PG PG PG Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317 Query: 1810 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 1845 G PGE G GEKG++G TG GP GLPG PG +GE Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377 Query: 1846 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 1878 GPPG G GPPGPPG PG G +G GPPG Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415 Score = 231 bits (588), Expect = 7e-60 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GP G PG G PG +G G GI G IGPPGP G +GPPGP G PGP+G GL+ G +G Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227 Query: 1643 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 1685 +G +G G PG PG+ G GLPG GP GPPG RG G + G Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 1686 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 1745 G +G PG G PG G G G PG PGD G PG G GEKG +GD V Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 1746 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 1792 + + G+ L +P + Q PGPPG PPGPPG G R Sbjct: 348 RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 1793 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 1839 G+ G G PG PG PG+ G PG GLPG G G G GP G PG Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 1840 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 1882 G QGE +GPPG G G PGPPG G G +G G G Sbjct: 466 GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525 Query: 1883 SQCASIP--YNGQGYPGS 1898 IP G+PGS Sbjct: 526 KGLPGIPGAPGAPGFPGS 543 Score = 230 bits (587), Expect = 9e-60 Identities = 146/342 (42%), Positives = 166/342 (48%), Gaps = 38/342 (11%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 S+G PG PGP G PG G G GI G++G PG G G PG +G PG G G PG Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 1691 G +G+ G G PGLPG G G G PG GPPG++G G+DG GP G Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 1692 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 1749 PGPPG PG G G G PG PG+ G PGP KGE G G Q Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSP--G 1244 Query: 1750 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 1809 + G N P PGP GPPG PG+ G +GE G G+PG PG PG+ Sbjct: 1245 PALEGPKG------NPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298 Query: 1810 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 1861 QGPPG +G PG G G G G G+PG PG +G S GP G G GPPGP Sbjct: 1299 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358 Query: 1862 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 1897 PG PG SG I+G GPPG + P QG PG Sbjct: 1359 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1400 Score = 223 bits (568), Expect = 1e-57 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 1640 G PG PGP G G G +GE+G +GA GP G G G PG G PG +G G L+ PG Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 MKGD GE G PG G PGLPG PG G PG G G+ G + +G GPPG+PG Sbjct: 556 -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610 Query: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 1754 PG+ G G G PG G PGP G KG +G G+ + Q + + G Sbjct: 611 PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669 Query: 1755 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 1801 R + +P D S+ +PG P G PGPPG G G PGP G P Sbjct: 670 NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727 Query: 1802 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 1843 G PG G++GPPG G PG KGE G G G RG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787 Query: 1844 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 1878 + GP G G G PGP G PG G++GPPGPPG Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828 Score = 219 bits (557), Expect = 3e-56 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 1636 G PG PGP G PG +GERG G G PG G+IGP GP G PPGP G G+ Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 1637 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 1684 PG+ G G KGD G+ PG PGR G GLPG PG G PG G G G Sbjct: 642 NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701 Query: 1685 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 1741 +G GPPGP G PG PG G G PG+ G G PGP G G KG+ G Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753 Query: 1742 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 1792 A+ + G F L + R PGPPGPPG P G G Sbjct: 754 ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 1793 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 1851 G+PGP G PG PG G+QGPPG G+PG G+ G G G +G PGPPG PG Sbjct: 805 GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857 Query: 1852 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 G RG PG PG PG G G PG PG +S G+PG+ Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894 Score = 218 bits (555), Expect = 4e-56 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%) Query: 1583 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 1628 GPPGPPG G PG KG +GE+G G G PG G+ G PG G PG Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 1629 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 1666 P GP GL IP G G G+ G+ GE G PG G PGLPG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386 Query: 1667 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 1708 PPG MGPPG GF G+ G G GPPG PG+PG PG GP+G Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446 Query: 1709 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 1763 +PG PG G PG GL+GE+G +GD C I ++ Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490 Query: 1764 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 1811 PG PG PG PG G+ G P GP G PG PG PG G Sbjct: 491 -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539 Query: 1812 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 1851 PG +G P G+KGE G+ G+ G GLPG PGP+GE P G Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595 Query: 1852 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 1879 T G RGPPG PG PG G GP GPPG+ Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625 Score = 215 bits (548), Expect = 3e-55 Identities = 126/287 (43%), Positives = 140/287 (48%), Gaps = 46/287 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP--GPQGPPGPQGPNGL-SIPG 1639 G PG PG G PG KG G G G GPPGP G GP GP+G PGPQGP G +PG Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPG 1267 Query: 1640 EQGRQGMKGDAG---EPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPG 1696 +G G+ G+ G E G PG+ G PGLPG G GPPG +G G+ G G +G PG PG Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1327 Query: 1697 SPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQM 1756 PG PG+ GPSG PG G G PG G G G Sbjct: 1328 VPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG--------------------------- 1360 Query: 1757 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 1816 +P S G GPPG PG G +G PGP G G PG G G PG Sbjct: 1361 ---------LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN 1411 Query: 1817 GLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPG 1863 GLPG G G G GLPG PG +G GPPG G +GPPGPPG Sbjct: 1412 GLPGFDG--AGGRKGDPGLPGQPGTRG--LDGPPGPDGLQGPPGPPG 1454 Score = 209 bits (532), Expect = 2e-53 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 1599 P FP S D + PG G G PG GP Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597 Query: 1600 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 1652 +GERG G G PG G+IGP GP GPPGP G G+ PG+ G G KGD G+ Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 1653 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 1697 PG PGR G GLPG PG G PG G G G +G GPPGP G Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717 Query: 1698 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 1757 PG PG G G PG+ G G PGP G G KG+ G A+ + G Sbjct: 718 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766 Query: 1758 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 1808 F L + R PGPPGP PGP G G G+PGP G PG PG G Sbjct: 767 -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819 Query: 1809 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 1861 +QGPPG G+PG G+ G G G +G PGP PGP GE G PG+ G GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 1862 PGRPGNS------------GIRGPPGPPG 1878 PG PG + G+ GPPGPPG Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 204 bits (520), Expect = 5e-52 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%) Query: 1581 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 1631 ++GP GPPG P G G KG +G G G G PGP+GD G PG G PG G Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 1632 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 1669 GL +PG+ G G+ G GEPG+PG G PG+PGPPG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 1670 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 1710 P GPPG G G GA+GP+G G PG PG PG TG G P Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 1711 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 1767 G GD +G+PGP G G G I Q I G + + L+ IP Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842 Query: 1768 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 1825 + + PGPPG PGPPG G+ G PG G G PG+PG+ G G G PG KGE Sbjct: 843 GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898 Query: 1826 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 1878 G G PGPPGP G R+G PG G G G PG PG +G +G PGPPG Sbjct: 899 GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 1879 YCDSSQCASIPYNGQ-GYPG 1897 D + S G+ G PG Sbjct: 954 PMDPNLLGSKGEKGEPGLPG 973 Score = 139 bits (349), Expect = 3e-32 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G PG PG G PG KGP G + G+ GP G G IGPPGP G PGP G + + I G+ G Sbjct: 1321 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1376 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 1702 G+ G G GLPG G GLPGP GP G PG G G DGA G +G PG PG PG+ G Sbjct: 1377 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1436 Query: 1703 VTGPSGKPGKPGDHGRPGPSGL 1724 + GP G G G G PG S + Sbjct: 1437 LDGPPGPDGLQGPPGPPGTSSV 1458 Score = 105 bits (263), Expect = 3e-22 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 1777 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 1836 PGP GPPGP G G G PGP G G G PG+ G PG GLPG G G+ GP+G+P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122 Query: 1837 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 1886 G G +GE G PG G +GPPGPPG PG G + GP G PGY Sbjct: 123 GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182 Query: 1887 SIPYNGQGYPG 1897 +P G PG Sbjct: 183 GLP-GPTGIPG 192 Score = 90.9 bits (224), Expect = 1e-17 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Query: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 1843 G G G RG PG G PG PG PG +GPPG RG G+ G G GP+G+ GPPG G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99 Query: 1844 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879 T G PG G+ GP G PG G G RG PG PG+ Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Score = 75.1 bits (183), Expect = 6e-13 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%) Query: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 1833 G P A A PG + G G +G G GL G G G G GPR Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 1834 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 1893 G+PGPPGP+G GPPG G G PG PG PG+ G GP G PG C+ ++ + Sbjct: 81 GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131 Query: 1894 GYPGS 1898 G+PGS Sbjct: 132 GFPGS 136 Score = 60.8 bits (146), Expect = 1e-08 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 1636 GPPG PG G PG G G +G G G PG RG GPPGP QGPPGP G + ++ Sbjct: 1403 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459 Score = 57.8 bits (138), Expect = 1e-07 Identities = 31/64 (48%), Positives = 32/64 (50%), Gaps = 6/64 (9%) Query: 1579 QDSVGPPGPPGPAGGPGAK------GPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 1632 Q G PGP GP G PG G G +G G G PG RG GPPGP G GP GP Sbjct: 1393 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1452 Query: 1633 NGLS 1636 G S Sbjct: 1453 PGTS 1456 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 253 bits (647), Expect = 1e-66 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 1628 GPPGPPG G GA GP+G+RG G GPPG P+GD+GP PGP GPPG Sbjct: 757 GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Query: 1629 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 1673 P GP G+ PG G G KGD G PGL PG G+PG+PG PGP+GP Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 1674 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 1721 PG G GK GA MGP GPPGP G PG GV G G G G G PGP Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 1722 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 1771 +G KG KG+ G + + L+ + + L I P YQ Sbjct: 937 TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 1772 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 1812 QPG PGPPGP G+ G G+PG PG G GFPG G++GP Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 1813 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 1865 PG GLPG+KG++G GLPG PGP+GE G PG GS G PG PG P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 1866 GNSGIRGPPGPPGY 1879 G G +G PG PG+ Sbjct: 1110 GTPGAKGQPGLPGF 1123 Score = 246 bits (629), Expect = 1e-64 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%) Query: 1582 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 1635 +GPPGPPGP +G PG KG G +G G GP G +G G PG GPPGP PN L Sbjct: 901 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Query: 1636 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 1674 IPG G +G +G G+PG PG +G PGLPGPPGP G P Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 1675 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 1723 GD GF G G GP GP G PG PGSPG+ G G G PG G PG G Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080 Query: 1724 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 1782 KGE G G + + +V L + L P PGPPGP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133 Query: 1783 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 1831 GPPG+ G GEPGP GG PG PG PG +G PG+ G+P GE G+ G G+ G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 1832 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 P GLPG G +G+ G PG+ G GP G PG G G++GPPGPPG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Score = 238 bits (606), Expect = 5e-62 Identities = 156/375 (41%), Positives = 185/375 (49%), Gaps = 59/375 (15%) Query: 1559 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 1618 +P + E P +P + + SVG PG PG G PGAKG G G G GPPGP+G Sbjct: 1078 LPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136 Query: 1619 GPPGPQGPPGPQGPNG-------LSIPGEQGRQGM---------KGDAGEPG-------- 1654 GPPG G PG GP G PGE+G+ G KG+ G+PG Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 1655 ---LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP-----GSPGVTGP 1706 L G+ G GLPG PG G PG +G G G G +GPPGPPGSP G G GP Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256 Query: 1707 SGKPGKPGDHGRPGP---------SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 1757 G PG+PG G PGP G+KGEKG+ G + Q L Q N Sbjct: 1257 QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL---QGN 1313 Query: 1758 RFNQMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG------- 1808 LN + D PG GP G PGSAG GEPG G PG PG PG Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1373 Query: 1809 MQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPP---GSTGSRGPPGPPG 1863 ++G G G+PG+ G +G G GP+GLPGP GP G+ R G P G+ G +G PG PG Sbjct: 1374 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1433 Query: 1864 RPGNSGIRGPPGPPG 1878 +PG G+ GPPGP G Sbjct: 1434 QPGTRGLDGPPGPDG 1448 Score = 237 bits (604), Expect = 9e-62 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 1636 +G PGPPGP G PG GP G G G IG GP G G PGP+G PGP GP GL Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764 Query: 1637 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 1679 PG +G G KGD G PG PGRTG GLPGP PGPMGPPG G Sbjct: 765 -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 1680 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 1716 G G G +G PGPP GSPG PG GP G PG PG Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883 Query: 1717 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 1774 G+ G SG G KG+ G + + + + G Q P + S+ Sbjct: 884 GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 1775 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 1832 +PG PGPPGP P G++GE G PG PG PG+ GP G +GLPG+ G+ G SG Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998 Query: 1833 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 1878 GLPGPPGP+G G PG G GPPG G PG G+ GPPGP G Sbjct: 999 PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048 Score = 236 bits (601), Expect = 2e-61 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%) Query: 1580 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 1634 D + PGPPGP G PG KG +GE+G+ G G G GPPG G PG GP G Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507 Query: 1635 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 1693 L PG++G +G G G GLPG G PG PG PG G PGD F G G G G PG Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 1694 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 1753 PG PG PG G G PG PG G PG KGE+G G+ + + Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617 Query: 1754 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 1801 G M F Q PG PG PGP PG G G PG G Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 1802 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 1855 G PG PG+ G PG G+PG KGE G G GP+G PG PGP G G PG G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735 Query: 1856 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GPPGPPG PG G + GPPGPPG + A P +G+PG Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781 Score = 234 bits (596), Expect = 8e-61 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%) Query: 1546 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 1605 CSP S+ C I + E P + G PG PGP G PG PRG++G Sbjct: 32 CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79 Query: 1606 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 1661 G GPPGP+G GPPG G PG G G+ PG QG G G GE G PG G Sbjct: 80 DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Query: 1662 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 1712 PGL GPPGP G PG +G G G G GPPG G PG G+ GP G PG Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 1713 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 1771 PG G PGP GL G KG+ G + Q Q Q G + ++ I ++Q Sbjct: 200 PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257 Query: 1772 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 1809 R PGPP GPPGPP G G +GEPG PG G+PG PG PG Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317 Query: 1810 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 1845 G PGE G GEKG++G TG GP GLPG PG +GE Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377 Query: 1846 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 1878 GPPG G GPPGPPG PG G +G GPPG Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415 Score = 231 bits (588), Expect = 7e-60 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GP G PG G PG +G G GI G IGPPGP G +GPPGP G PGP+G GL+ G +G Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227 Query: 1643 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 1685 +G +G G PG PG+ G GLPG GP GPPG RG G + G Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 1686 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 1745 G +G PG G PG G G G PG PGD G PG G GEKG +GD V Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 1746 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 1792 + + G+ L +P + Q PGPPG PPGPPG G R Sbjct: 348 RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 1793 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 1839 G+ G G PG PG PG+ G PG GLPG G G G GP G PG Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 1840 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 1882 G QGE +GPPG G G PGPPG G G +G G G Sbjct: 466 GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525 Query: 1883 SQCASIP--YNGQGYPGS 1898 IP G+PGS Sbjct: 526 KGLPGIPGAPGAPGFPGS 543 Score = 230 bits (586), Expect = 1e-59 Identities = 146/342 (42%), Positives = 167/342 (48%), Gaps = 35/342 (10%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 S+G PG PGP G PG G G GI G++G PG G G PG +G PG G G PG Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 1691 G +G+ G G PGLPG G G G PG GPPG++G G+DG GP G Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 1692 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 1749 PGPPG PG G G G PG PG+ G PGP KGE G G Q Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSP--G 1244 Query: 1750 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 1809 + G Q P + PGP GPPG PG+ G +GE G G+PG PG PG+ Sbjct: 1245 PALEGPKGNPGP---QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301 Query: 1810 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 1861 QGPPG +G PG G G G G G+PG PG +G S GP G G GPPGP Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361 Query: 1862 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 1897 PG PG SG I+G GPPG + P QG PG Sbjct: 1362 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1403 Score = 223 bits (568), Expect = 1e-57 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 1640 G PG PGP G G G +GE+G +GA GP G G G PG G PG +G G L+ PG Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 MKGD GE G PG G PGLPG PG G PG G G+ G + +G GPPG+PG Sbjct: 556 -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610 Query: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 1754 PG+ G G G PG G PGP G KG +G G+ + Q + + G Sbjct: 611 PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669 Query: 1755 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 1801 R + +P D S+ +PG P G PGPPG G G PGP G P Sbjct: 670 NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727 Query: 1802 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 1843 G PG G++GPPG G PG KGE G G G RG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787 Query: 1844 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 1878 + GP G G G PGP G PG G++GPPGPPG Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828 Score = 219 bits (557), Expect = 3e-56 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 1636 G PG PGP G PG +GERG G G PG G+IGP GP G PPGP G G+ Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 1637 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 1684 PG+ G G KGD G+ PG PGR G GLPG PG G PG G G G Sbjct: 642 NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701 Query: 1685 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 1741 +G GPPGP G PG PG G G PG+ G G PGP G G KG+ G Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753 Query: 1742 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 1792 A+ + G F L + R PGPPGPPG P G G Sbjct: 754 ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 1793 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 1851 G+PGP G PG PG G+QGPPG G+PG G+ G G G +G PGPPG PG Sbjct: 805 GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857 Query: 1852 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 G RG PG PG PG G G PG PG +S G+PG+ Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894 Score = 218 bits (555), Expect = 4e-56 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%) Query: 1583 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 1628 GPPGPPG G PG KG +GE+G G G PG G+ G PG G PG Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 1629 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 1666 P GP GL IP G G G+ G+ GE G PG G PGLPG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386 Query: 1667 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 1708 PPG MGPPG GF G+ G G GPPG PG+PG PG GP+G Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446 Query: 1709 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 1763 +PG PG G PG GL+GE+G +GD C I ++ Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490 Query: 1764 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 1811 PG PG PG PG G+ G P GP G PG PG PG G Sbjct: 491 -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539 Query: 1812 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 1851 PG +G P G+KGE G+ G+ G GLPG PGP+GE P G Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595 Query: 1852 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 1879 T G RGPPG PG PG G GP GPPG+ Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625 Score = 211 bits (536), Expect = 7e-54 Identities = 129/312 (41%), Positives = 144/312 (46%), Gaps = 67/312 (21%) Query: 1579 QDSVGPPGP---------------PGPAGGPGAKGPRGE---RGISGAIGPPGPRGDIGP 1620 Q G PGP PG G PG GP+GE G G GPPGP G GP Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245 Query: 1621 --PGPQGPPGPQGPNG----LSIPGEQGRQGMKGDA---GEPGLPGRTGTPGLPGPPGPM 1671 GP+G PGPQGP G +PG +G G+ G+ GE G PG+ G PGLPG G Sbjct: 1246 ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305 Query: 1672 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 1731 GPPG +G G+ G G +G PG PG PG PG+ GPSG PG G G PG G G G Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG-- 1363 Query: 1732 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGA 1791 +P S G GPPG PG G Sbjct: 1364 ----------------------------------LPGPSGQSIIIKGDAGPPGIPGQPGL 1389 Query: 1792 RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPG 1851 +G PGP G G PG G G PG GLPG G G G GLPG PG +G GPPG Sbjct: 1390 KGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG--AGGRKGDPGLPGQPGTRG--LDGPPG 1445 Query: 1852 STGSRGPPGPPG 1863 G +GPPGPPG Sbjct: 1446 PDGLQGPPGPPG 1457 Score = 209 bits (532), Expect = 2e-53 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 1599 P FP S D + PG G G PG GP Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597 Query: 1600 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 1652 +GERG G G PG G+IGP GP GPPGP G G+ PG+ G G KGD G+ Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 1653 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 1697 PG PGR G GLPG PG G PG G G G +G GPPGP G Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717 Query: 1698 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 1757 PG PG G G PG+ G G PGP G G KG+ G A+ + G Sbjct: 718 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766 Query: 1758 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 1808 F L + R PGPPGP PGP G G G+PGP G PG PG G Sbjct: 767 -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819 Query: 1809 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 1861 +QGPPG G+PG G+ G G G +G PGP PGP GE G PG+ G GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 1862 PGRPGNS------------GIRGPPGPPG 1878 PG PG + G+ GPPGPPG Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 204 bits (520), Expect = 5e-52 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%) Query: 1581 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 1631 ++GP GPPG P G G KG +G G G G PGP+GD G PG G PG G Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 1632 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 1669 GL +PG+ G G+ G GEPG+PG G PG+PGPPG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 1670 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 1710 P GPPG G G GA+GP+G G PG PG PG TG G P Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 1711 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 1767 G GD +G+PGP G G G I Q I G + + L+ IP Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842 Query: 1768 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 1825 + + PGPPG PGPPG G+ G PG G G PG+PG+ G G G PG KGE Sbjct: 843 GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898 Query: 1826 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 1878 G G PGPPGP G R+G PG G G G PG PG +G +G PGPPG Sbjct: 899 GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 1879 YCDSSQCASIPYNGQ-GYPG 1897 D + S G+ G PG Sbjct: 954 PMDPNLLGSKGEKGEPGLPG 973 Score = 139 bits (349), Expect = 3e-32 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G PG PG G PG KGP G + G+ GP G G IGPPGP G PGP G + + I G+ G Sbjct: 1324 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1379 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 1702 G+ G G GLPG G GLPGP GP G PG G G DGA G +G PG PG PG+ G Sbjct: 1380 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1439 Query: 1703 VTGPSGKPGKPGDHGRPGPSGL 1724 + GP G G G G PG S + Sbjct: 1440 LDGPPGPDGLQGPPGPPGTSSV 1461 Score = 105 bits (263), Expect = 3e-22 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 1777 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 1836 PGP GPPGP G G G PGP G G G PG+ G PG GLPG G G+ GP+G+P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122 Query: 1837 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 1886 G G +GE G PG G +GPPGPPG PG G + GP G PGY Sbjct: 123 GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182 Query: 1887 SIPYNGQGYPG 1897 +P G PG Sbjct: 183 GLP-GPTGIPG 192 Score = 90.9 bits (224), Expect = 1e-17 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Query: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 1843 G G G RG PG G PG PG PG +GPPG RG G+ G G GP+G+ GPPG G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99 Query: 1844 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879 T G PG G+ GP G PG G G RG PG PG+ Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Score = 75.1 bits (183), Expect = 6e-13 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%) Query: 1784 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 1833 G P A A PG + G G +G G GL G G G G GPR Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 1834 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 1893 G+PGPPGP+G GPPG G G PG PG PG+ G GP G PG C+ ++ + Sbjct: 81 GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131 Query: 1894 GYPGS 1898 G+PGS Sbjct: 132 GFPGS 136 Score = 60.8 bits (146), Expect = 1e-08 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 1636 GPPG PG G PG G G +G G G PG RG GPPGP QGPPGP G + ++ Sbjct: 1406 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462 >gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo sapiens] Length = 678 Score = 253 bits (647), Expect = 1e-66 Identities = 148/353 (41%), Positives = 177/353 (50%), Gaps = 45/353 (12%) Query: 1578 TQDSVGPPGPPGPAGG---------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 T+ G PGPPG AG PGAKG GE+G +GA G PG G+ G PG QGPPG Sbjct: 311 TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 370 Query: 1629 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--------------- 1672 GP G +PG +G G G G PG G G+PGLPG PGP G Sbjct: 371 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 430 Query: 1673 PPGDRGFTGKDGAMGPRGP------PGPPGS---PGSPGVTGPSGKPGKPGDHGRPGPSG 1723 P G++G +G++G G RG PGP GS PG PG+ GP G G PG G GP G Sbjct: 431 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490 Query: 1724 LKGEKGDRGDIASQNMMRAVAR--------QVCEQLISGQMNRFNQMLNQIPNDYQSSRN 1775 +G +G++G + R QVC ++I L + + Sbjct: 491 PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550 Query: 1776 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGL 1835 +PGPPGPPGPPG G G+ G G PG G PG G G +G GEKGERG GP GL Sbjct: 551 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGL 610 Query: 1836 PGP---PGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQC 1885 PG PG G + G G G RGPPG G PG G GPPG PG+C+ + C Sbjct: 611 PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 663 Score = 241 bits (614), Expect = 6e-63 Identities = 139/328 (42%), Positives = 170/328 (51%), Gaps = 38/328 (11%) Query: 1575 CTCTQDSVGPPGPPGPAGGPGA---KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 1631 C + G GPPGP G PG G G+RG G GPPGP G+ G PG G PG G Sbjct: 21 CAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 80 Query: 1632 PNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTP--GLPGPPGPMGP---PGDRGFTGKDGA 1685 +GL+ P G G G KG GEPG+PG G P G+PGPPGP G PG+ G G G Sbjct: 81 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGD 140 Query: 1686 MGPRGPPGPPGSPGSPGVTG--------PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQ 1737 G RGPPGPPG PG G G P+ P PG G PG G++G KG +G+I Sbjct: 141 PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP--PGRSGYPGLPGMRGHKGAKGEIGEP 198 Query: 1738 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 1797 + G ++ Q P Q R G G G G+ G GEPGP Sbjct: 199 GRQGHKGEE-------GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251 Query: 1798 GGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGES-------RTGPP 1850 G PG PG G +GPPGE G G++ G+ G RG+PG PGP+G++ R G P Sbjct: 252 QGLPGAPGDQGQRGPPGEAGPKGDR-----GAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306 Query: 1851 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G G++G PG PG PG++G++G PG PG Sbjct: 307 GMPGTKGEPGKPGPPGDAGLQGLPGVPG 334 Score = 232 bits (591), Expect = 3e-60 Identities = 149/358 (41%), Positives = 174/358 (48%), Gaps = 41/358 (11%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 P PN+C + G PG PG G GAKG GE G G G G +G++G G QGPPG Sbjct: 166 PLCPNACPPGRS--GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 223 Query: 1629 PQGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK-- 1682 QG G++ GE+G +G+ G+ G GLPG G G GPPG GP GDRG G Sbjct: 224 AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 283 Query: 1683 -DGAMGPRGPPGPPGS------PGSPGVTGPSGKPGKPGDHGR---------PGPSGLKG 1726 G GP+G G PG PG PG G GKPG PGD G PG G+ G Sbjct: 284 IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG 343 Query: 1727 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 1786 EKG G M + GQ ++ + P SR + GP G PG P Sbjct: 344 EKGSTGAPGKPGQMGNSGKP-------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 396 Query: 1787 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPRGLPGP---P 1839 G G+ G PG G PG PG PGM+G G G PG KGE+G G +G RG G P Sbjct: 397 GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 456 Query: 1840 GPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 GP+G + G PG G RGP G G PG G RGPPGP G +P QG PG Sbjct: 457 GPKGSA--GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP-GVQGPPG 511 Score = 212 bits (539), Expect = 3e-54 Identities = 148/393 (37%), Positives = 168/393 (42%), Gaps = 101/393 (25%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---PRGDIG------------------PP 1621 G PG G G PG GP+G+RG GA G PG P+GD G P Sbjct: 256 GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315 Query: 1622 GPQGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 1680 G GPPG G GL +PG G +G+ G+ G G PG+ G G G PG GPPG+ G Sbjct: 316 GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375 Query: 1681 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 1740 G G G RG GP GSPG PG G G PG PG PGP GL G KGDRG + Sbjct: 376 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPK 432 Query: 1741 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG---P 1797 EQ SG+ + R + G G PGP GSAG GEPG P Sbjct: 433 G-------EQGASGEEGEAGE------------RGELGDIGLPGPKGSAGNPGEPGLRGP 473 Query: 1798 GGRPGFPGTPGMQGPPGERGLPGEKGERG------------------------------- 1826 G G PG G +GPPG RG+ GE+G G Sbjct: 474 EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533 Query: 1827 ------------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGP- 1873 TG G G PGPPGP GE+ G PG G RG PG G PG G+RGP Sbjct: 534 MAASLKRPDSGATGLPGRPGPPGPPGPPGEN--GFPGQMGIRGLPGIKGPPGALGLRGPK 591 Query: 1874 --------PGPPGYCDSSQCASIPYNGQGYPGS 1898 GPPG + +I G P S Sbjct: 592 GDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 624 Score = 107 bits (268), Expect = 8e-23 Identities = 79/245 (32%), Positives = 90/245 (36%), Gaps = 95/245 (38%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL------ 1635 VG PGP G G G +G GERG G IG PGP+G G PG G GP+G GL Sbjct: 426 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 485 Query: 1636 -------SIPGEQGRQGMKGDAGEPGLP------------------------------GR 1658 + GEQG G+ G G PG G Sbjct: 486 RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545 Query: 1659 TGTPGLPGPPGPMGPPGDRGFTGK------------DGAMGPRGPPG---------PPGS 1697 TG PG PGPPGP GPPG+ GF G+ GA+G RGP G PPG Sbjct: 546 TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 605 Query: 1698 -------------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKG 1726 PG G+ G G PG PG G P+ Sbjct: 606 GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 665 Query: 1727 EKGDR 1731 + G R Sbjct: 666 QAGQR 670 Score = 84.3 bits (207), Expect = 1e-15 Identities = 51/121 (42%), Positives = 60/121 (49%), Gaps = 25/121 (20%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG------PRGDIGPPGPQGPPGPQGPNGL- 1635 GPPGPPGP G G G G RG+ G GPPG P+GD+G G +GPPG +GPNGL Sbjct: 553 GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 611 Query: 1636 ---SIPGEQG-----RQGMKGDAGEPGL---------PGRTGTPGLPGPPGPMGPPGDRG 1678 +PG+ G R G G+ G PG+ PG G PG P G R Sbjct: 612 GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 671 Query: 1679 F 1679 F Sbjct: 672 F 672 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 252 bits (644), Expect = 2e-66 Identities = 152/361 (42%), Positives = 173/361 (47%), Gaps = 34/361 (9%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 1628 PA P G PGPPGPAG G G G+ G G G G +GD GPPGP GP G Sbjct: 789 PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848 Query: 1629 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMG 1687 P GP G + PG +G +G G G G PG G G PGP G GPPG G GK+G G Sbjct: 849 PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908 Query: 1688 PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQV 1747 PRG GP G PG G GP G G+ G G GP+G G G +G IA Q + + Q Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG-IAGQRGVVGLPGQR 967 Query: 1748 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---PPGSAGARGEPGPGGRPGFP 1804 E+ G + Q P+ R PGP GPPG PPG +G G PG G PG Sbjct: 968 GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD 1027 Query: 1805 GTPGMQG---------PPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTG 1854 G+PG +G PPG G PG G G G SG RG GP GP G GP G+ G Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP--VGPVGARG 1085 Query: 1855 SRGPPGPPGRPGN---------------SGIRGPPGPPGYC--DSSQCASIPYNGQGYPG 1897 GP GP G G SG++GPPGPPG AS P +G PG Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPG 1145 Query: 1898 S 1898 S Sbjct: 1146 S 1146 Score = 250 bits (638), Expect = 1e-65 Identities = 151/361 (41%), Positives = 177/361 (49%), Gaps = 59/361 (16%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G PGPPG GGPG++G G G++G GP G RG GP GP+G PG G PGE G Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR-----PGEAG 533 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGP------PGPMGPPGDRGFTGKDGAMGPRGPPGPPG 1696 G KG G PG PG G G PGP PGP GPPG RG G G GP+G G PG Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593 Query: 1697 S------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR--------A 1742 PG PG GP+GK G+ G G PGP+G GE+G++G S Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653 Query: 1743 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP------PGSAGARGEPG 1796 A + EQ + G + + + R GPPGP GP PG+ GA+G+ G Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713 Query: 1797 PGGRPGFPGTPGMQGPPGERG---LPGEKGERGT----------GSSGPRGLPGPPGPQG 1843 G PG G PG+QG PGERG LPG KG+RG G G RGL GP GP G Sbjct: 714 APGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773 Query: 1844 ESRTGPPGSTGSRGPPGPPG------RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 1897 + G PG G GP GP G PG+ G GPPGP G+ P G PG Sbjct: 774 PA--GAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG-------PPGADGQPG 824 Query: 1898 S 1898 + Sbjct: 825 A 825 Score = 248 bits (634), Expect = 3e-65 Identities = 142/314 (45%), Positives = 159/314 (50%), Gaps = 36/314 (11%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 + GPPGPPGPAG G KGPRGE G +G G GP G GP G +G PG GP G PG Sbjct: 891 NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGA--PGT 948 Query: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 G QG+ G G GLPG+ G G PG PGP G PG + G GA G RGPPGP G PG Sbjct: 949 PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ---GPSGASGERGPPGPMGPPGL 1005 Query: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 1760 G G SG+ G PG G PG G G KGDRG+ A + Sbjct: 1006 AGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG------- 1058 Query: 1761 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR---------------PGFPG 1805 P R + GP GP GP G GARG GP G G G Sbjct: 1059 ------PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRG 1112 Query: 1806 TPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGR 1864 G+QGPPG G PGE+G +G+SGP G GPPG G + G G G GPPGP GR Sbjct: 1113 FSGLQGPPGPPGSPGEQGP--SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170 Query: 1865 PGNSGIRGPPGPPG 1878 G++G GPPGPPG Sbjct: 1171 TGDAGPVGPPGPPG 1184 Score = 248 bits (633), Expect = 4e-65 Identities = 147/351 (41%), Positives = 170/351 (48%), Gaps = 41/351 (11%) Query: 1560 PSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIG 1619 P+ +D P P +G PGP G AG PG G RG G GA+GP G G+ G Sbjct: 558 PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAG 617 Query: 1620 PPGPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPG 1675 GP GP GP G G PG QG G G GE G PG G PG G PGP G G Sbjct: 618 AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARG 677 Query: 1676 DRGFTGKDGAMGPRGPPGP---PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE----- 1727 +RGF G+ G GP GP GP G+PG+ G G +G PG PG G PG G+ GE Sbjct: 678 ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737 Query: 1728 ----KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 1783 KGDRGD + + + G + P + + GP GP Sbjct: 738 LPGPKGDRGDAGPKGADGSPGK-------DGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790 Query: 1784 GPPGSAGA---RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP 1839 GP G+ GA RGEPGP G GF G PG G PG +G PG+ G +G G GP G GPP Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850 Query: 1840 GPQGESRTGPPGSTGSRGPPGPPGR------------PGNSGIRGPPGPPG 1878 GP G G PG+ G+RG GPPG PG SG GPPGPPG Sbjct: 851 GPIG--NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG 899 Score = 248 bits (632), Expect = 5e-65 Identities = 157/387 (40%), Positives = 173/387 (44%), Gaps = 95/387 (24%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGG------------PGAKGPRGERGISGAIGPPGPRG 1616 P P Q G PGPPGPAG PGAKG G GI+GA G PG RG Sbjct: 357 PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416 Query: 1617 DIGPPGPQGPPGPQGPNG-------------LSIPGEQGRQGMKGDAGEPGLPGRTGTPG 1663 GP GP GPPGP+G +G PG G QG G AGE G G G PG Sbjct: 417 PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG 476 Query: 1664 ---LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPG 1720 LPGPPG G PG RGF G DG GP+GP G GSPG G G G+ G+PG+ G PG Sbjct: 477 PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPG 536 Query: 1721 PSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPP 1780 GL G G G P +PGPP Sbjct: 537 AKGLTGSPGSPGPDGKTG----------------------------PPGPAGQDGRPGPP 568 Query: 1781 GPPGP---------PGSAGARGEPGPGGRPGFPGTP------------GMQGPPGERGLP 1819 GPPG PG GA GEPG G G PG P G QGPPG G Sbjct: 569 GPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628 Query: 1820 GEKGERG-TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGR------PGNSGIR 1871 GE+GE+G GS G +GLPGP GP GE+ + G G G G PGP G PG G++ Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688 Query: 1872 GPPGPPGYCDSSQCASIPYNGQGYPGS 1898 GPPGP G P G PG+ Sbjct: 689 GPPGPAG----------PRGANGAPGN 705 Score = 243 bits (620), Expect = 1e-63 Identities = 135/297 (45%), Positives = 151/297 (50%), Gaps = 51/297 (17%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GP GPPGPAG PG KG SG GP GP G G PG +G PGP GP G + G G Sbjct: 767 GPIGPPGPAGAPGDKGE------SGPSGPAGPTGARGAPGDRGEPGPPGPAGFA--GPPG 818 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 1702 G G GEPG G G G PGP GP GPPG G G GA G RG GPPG+ G PG Sbjct: 819 ADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPG 878 Query: 1703 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 1762 G G PG G+ G PGP G G++G +G Sbjct: 879 AAGRVGPPGPSGNAGPPGPPGPAGKEGGKG------------------------------ 908 Query: 1763 LNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEK 1822 P +PG GPPGPPG AG +G PG G G PGTPG QG G+RG+ G Sbjct: 909 ----PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964 Query: 1823 GERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G+R G RG PG PGP GE + GP G++G RGPPGP G P G+ GPPG G Sbjct: 965 GQR-----GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP---GLAGPPGESG 1013 Score = 239 bits (609), Expect = 2e-62 Identities = 142/331 (42%), Positives = 164/331 (49%), Gaps = 46/331 (13%) Query: 1583 GPPGPPGPAG----------------------GPGAKGPRGERGISGAIGPPGPRGDIGP 1620 GPPGPPGP G PG GP G RG+ G G PGP+G GP Sbjct: 145 GPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP 204 Query: 1621 PGPQGPPGPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPG------LPGPPGPMGP 1673 PG G PG GP G PG G+ G G+AG+PG PG G PG LPG G G Sbjct: 205 PGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGM 264 Query: 1674 PGDRGFTGKDGAMG---PRGPPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLKGE 1727 G RGF+G DGA G P GP G PGSP G+PG GP G PG+ G G PGP+G +G Sbjct: 265 KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324 Query: 1728 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 1787 G G G + + Q P + + G PGPPGP G Sbjct: 325 DGATGAAGPPGPTGPAG----PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG 380 Query: 1788 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRT 1847 +AG G PG G+ PG G G PG G PG G R G SGP+G GPPGP+G S Sbjct: 381 AAGPAGNPGADGQ---PGAKGANGAPGIAGAPGFPGAR--GPSGPQGPGGPPGPKGNS-- 433 Query: 1848 GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G PG+ GS+G G G PG G++GPPGP G Sbjct: 434 GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464 Score = 238 bits (607), Expect = 4e-62 Identities = 141/319 (44%), Positives = 161/319 (50%), Gaps = 64/319 (20%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS---- 1636 + GPPGP GPAG PG G G +G +G P GPRG GP G +G PGP GP G + Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAG---PQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386 Query: 1637 IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM---GPPGDRGFTGKDGAMGPRGPPG 1693 PG G+ G KG G PG+ G G PG GP GP GPPG +G +G+ GA G +G G Sbjct: 387 NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG 446 Query: 1694 PPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 1750 G PG GV GP+G+ GK G G PGP+GL G G+RG Sbjct: 447 AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG----------------- 489 Query: 1751 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 1810 SR PG G GP G AG RG PGP G G+PG Sbjct: 490 --------------------PGSRGFPGADGVAGPKGPAGERGSPGPAGP---KGSPGEA 526 Query: 1811 GPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG-ESRTGPPGSTGSR---------GPP 1859 G PGE GLPG KG G+ GS GP G GPPGP G + R GPPG G+R GP Sbjct: 527 GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK 586 Query: 1860 GPPGRPGNSGIRGPPGPPG 1878 G G PG +G RG PGPPG Sbjct: 587 GAAGEPGKAGERGVPGPPG 605 Score = 225 bits (573), Expect = 4e-58 Identities = 136/333 (40%), Positives = 154/333 (46%), Gaps = 55/333 (16%) Query: 1560 PSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAG------------GPGAKGPRGERGISG 1607 P+ ++ GK P VGPPGPPGPAG PG GP+G G G Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959 Query: 1608 AIGPPGPRGDIG---PPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGL 1664 +G PG RG+ G PGP G PG QGP+G S GE+G G G G G PG +G G Sbjct: 960 VVGLPGQRGERGFPGLPGPSGEPGKQGPSGAS--GERGPPGPMGPPGLAGPPGESGREGA 1017 Query: 1665 PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 1724 PG G G G G G G GP GPPG PG+PG+PG GP+GK G G+ G GP+G Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077 Query: 1725 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 1784 G G RG Q P + + G G G Sbjct: 1078 VGPVGARGPAGPQG----------------------------PRGDKGETGEQGDRGIKG 1109 Query: 1785 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE 1844 G +G +G PGP G PG G G GP G RG PG G G G GLPGP GP Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG--APGKDGLNGLPGPIGP--- 1164 Query: 1845 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 1877 GP G TG GP GPPG PG GPPGPP Sbjct: 1165 --PGPRGRTGDAGPVGPPGPPGPP---GPPGPP 1192 Score = 140 bits (352), Expect = 2e-32 Identities = 101/274 (36%), Positives = 117/274 (42%), Gaps = 44/274 (16%) Query: 1662 PGLPGPPG---PMGPPGDRGFTGKD--GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH 1716 PG P G P+ P G T ++ G GP+G GP G G G G G PG+PG Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141 Query: 1717 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM------LNQIPNDY 1770 G PGP G G G G+ A Q + + G M P + Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201 Query: 1771 QSSRNQPGPP---------GPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP---PGERGL 1818 Q +PG P GPPGPPG G GE G GRPG G PG QG PG GL Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261 Query: 1819 PGEKGERG----------TGSSGPRGLPGPPGPQG-ESRTGP---PGSTGSRGPPGPPGR 1864 PG KG RG G +GP+G PG PG G + GP PG G G PGP G Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321 Query: 1865 PGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 GN G G GPPG + P G+PG+ Sbjct: 322 RGNDGATGAAGPPG-------PTGPAGPPGFPGA 348 Score = 73.2 bits (178), Expect = 2e-12 Identities = 34/60 (56%), Positives = 35/60 (58%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 GP GP GP G GA G G G+ G IGPPGPRG G GP GPPGP GP G P G Sbjct: 1136 GPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 252 bits (643), Expect = 3e-66 Identities = 150/347 (43%), Positives = 169/347 (48%), Gaps = 66/347 (19%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG----LS 1636 + GPPGPPG AG PG +G GERG G+ GP G +G+ G PG G PG GP G + Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768 Query: 1637 IPGEQGRQGMKGDAGEPGLPGRTGTPGLP------GPPGPMGPPGDRGFTGKDGAMGPRG 1690 PG G+ G KG+ G PGLPG G G P GPPGP G PG G G+ G G RG Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828 Query: 1691 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 1750 PG G G PGV GP PG G G PGP G+KGE+G G + Sbjct: 829 APGEKGEGGPPGVAGP---PGGSGPAGPPGPQGVKGERGSPGGPGAAG------------ 873 Query: 1751 LISGQMNRFNQMLNQIPNDYQSSRNQPGP------PGPPGPPGSAGARGEPGPGGRPGFP 1804 + +R PGP PGPPGP GS G G PGP G G P Sbjct: 874 -------------------FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914 Query: 1805 GTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGPPG 1860 G+PG+ GP G+ G PGEKG G+ GP G PGP G G GPPG G RG PG Sbjct: 915 GSPGVSGPKGDAGQPGEKG--SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG 972 Query: 1861 P---------PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 P PG G SG RGPPGP G + A P G PGS Sbjct: 973 PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP-GRDGNPGS 1018 Score = 250 bits (638), Expect = 1e-65 Identities = 147/330 (44%), Positives = 167/330 (50%), Gaps = 27/330 (8%) Query: 1560 PSRRDEGKCPAFPNSC--TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGD 1617 P + EG P P + G GPPGPAG PGA G GE G G G PG +G+ Sbjct: 776 PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE 835 Query: 1618 IGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDR 1677 GPPG GPPG GP G PG QG +G +G G PG G G GLPGPPG G PG Sbjct: 836 GGPPGVAGPPGGSGPAGP--PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893 Query: 1678 GFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH---------GRPGPSGLKGEK 1728 G +G G GP GP G G+PGSPGV+GP G G+PG+ G PGP G+ G Sbjct: 894 GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT 953 Query: 1729 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGS 1788 G RG +A M Q + G+ + N R GPPGP G PG Sbjct: 954 GARG-LAGPPGMPGPRGSPGPQGVKGESGKPG------ANGLSGER---GPPGPQGLPGL 1003 Query: 1789 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTG 1848 AG GEPG G PG G PG G PG +G GE G G+ G G PGPPGP G + G Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG--SPGAPGAPGHPGPPGPVGPA--G 1059 Query: 1849 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G G GP GP G PG +G RG PGP G Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQG 1089 Score = 247 bits (630), Expect = 9e-65 Identities = 145/329 (44%), Positives = 163/329 (49%), Gaps = 40/329 (12%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIG------------PPGPRGDIGPPGPQGPPGPQ 1630 GPPG GPAG PG +G +GERG G G PPG G+ GPPGP G PG Sbjct: 843 GPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD 902 Query: 1631 GPNG----LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAM 1686 GP G PG G G KGDAG+PG G+PG GPPG GP G G TG G Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDAGQPG---EKGSPGAQGPPGAPGPLGIAGITGARGLA 959 Query: 1687 GPRGPPGPPGSPGSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 1743 GP G PGP GSPG GV G SGKPG G+ G PGP GL G G G+ + Sbjct: 960 GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019 Query: 1744 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 1803 + G+ +R P + PGPPGP GP G +G RGE GP G G Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPG----APGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075 Query: 1804 PGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE----SRTGP 1849 PG G +G PG +G G+KGE G G G G PG PGP G+ GP Sbjct: 1076 PGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP 1135 Query: 1850 PGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 G G GP GPPG+ G SG GP GPPG Sbjct: 1136 AGPRGPVGPSGPPGKDGTSGHPGPIGPPG 1164 Score = 245 bits (625), Expect = 3e-64 Identities = 158/366 (43%), Positives = 173/366 (47%), Gaps = 63/366 (17%) Query: 1582 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQ------------GPPGP 1629 +G PGP G G PG G RG G G GPPG G+ GP GP GPPGP Sbjct: 578 MGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637 Query: 1630 QGPNGL----SIPGEQGR---QGMKGDAGEPGLPGRTGTPGLP---GPPGPMGPPGDRGF 1679 QG GL PGE G+ G KGDAG PG PG G G P GPPG G PG RG Sbjct: 638 QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697 Query: 1680 TGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIASQ 1737 G G G +G GPPG PG+ G G G PG+ G G PGP G KGE G G + + Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757 Query: 1738 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 1797 + R + +GQ P D + PG PG GP GS G RGE GP Sbjct: 758 DGPRGPTGPIGPPGPAGQ-----------PGD-KGEGGAPGLPGIAGPRGSPGERGETGP 805 Query: 1798 GGRPGFPGTPGMQGPP---GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGESRT 1847 G GFPG PG G P GERG PGEKGE G G SGP G PGP G +GE + Sbjct: 806 PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGS 865 Query: 1848 ----------------GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYN 1891 GPPGS G+ GPPGP G PG G GP G G S S P Sbjct: 866 PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG-APGSPGVSGPKG 924 Query: 1892 GQGYPG 1897 G PG Sbjct: 925 DAGQPG 930 Score = 239 bits (611), Expect = 1e-62 Identities = 138/330 (41%), Positives = 160/330 (48%), Gaps = 20/330 (6%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IPGEQ 1641 GPPGP G G PG +G GE G +GA G PGPRG+ G G G PG +G +G PGE Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473 Query: 1642 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSP 1701 G G+ G AGE G PG G G G PG GP G+RG G G G G PG G PG P Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533 Query: 1702 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIA-----SQNMMRAVARQVCEQLISGQM 1756 G+ G G PG PG G+PGP G +GE G G Q + G+ Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593 Query: 1757 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 1816 P + GP GPPGP G G +G+ GP G G G PG GPPGE Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653 Query: 1817 GLPGEKGERGTGSSGPRGLPGPPGPQGES----RTGPPGSTGS---RGPPGPPGRPGNSG 1869 G PGE G +G G PG PG +G++ GPPG G+ RG GPPG G G Sbjct: 654 GKPGEPGPKGDA-----GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708 Query: 1870 IRGPPGPPGYCDSSQCASIP--YNGQGYPG 1897 GPPGPPG + +P G G PG Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738 Score = 234 bits (596), Expect = 8e-61 Identities = 143/354 (40%), Positives = 166/354 (46%), Gaps = 37/354 (10%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-------L 1635 G PGP GP G PG +G G G +GA G G RG G PGP GPPG G G + Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRG------FTGKDGAMGPR 1689 G G G G GEPG G G G PGPPG G PG +G G G MG R Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413 Query: 1690 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIASQNMMRAVARQV 1747 GPPGP G+ G+PG+ G +G+PGK G G PGP G +GE G G ++ + Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473 Query: 1748 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP 1807 + G + P + GP G G PG AG RG G GR G PG P Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533 Query: 1808 GMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQG-------------ESRTGPPGST 1853 GM+G PG G PG G+ G GS G G PGPPGP G + G PG Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593 Query: 1854 GSR------GPPGPPGRPGNSGIRGPPGP--PGYCDSSQCASIPYNGQGYPGSG 1899 G R GP GPPG+ G +G +GPPGP PG P QG PG+G Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647 Score = 231 bits (589), Expect = 5e-60 Identities = 141/332 (42%), Positives = 161/332 (48%), Gaps = 28/332 (8%) Query: 1586 GPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQG 1645 GP GP G PG KGP GERG A GP GPRG G PG G PG G G+ PG G G Sbjct: 492 GPAGPNGIPGEKGPAGERG---APGPAGPRGAAGEPGRDGVPGGPGMRGM--PGSPGGPG 546 Query: 1646 MKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTG 1705 G G PG G +G PG PGP GP G PG GF G G G G G G PG PG G Sbjct: 547 SDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606 Query: 1706 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQML 1763 P GK G+ G G PGP+G G+KGD G Q + + E G+ Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666 Query: 1764 NQIPNDYQSSRNQPGPPGPP------------GPPGSAGARGEPGPGGRPGFPGTPGMQG 1811 + PG GPP GPPG G +G GP G PG GTPG+QG Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726 Query: 1812 PPGER---GLPGEKGERG-TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPG 1866 PGER G PG KG++G G G G+PG GP+G + GPPG G G G G PG Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786 Query: 1867 NSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 GI GP G PG + + P G+PG+ Sbjct: 787 LPGIAGPRGSPG----ERGETGPPGPAGFPGA 814 Score = 229 bits (584), Expect = 2e-59 Identities = 152/398 (38%), Positives = 167/398 (41%), Gaps = 81/398 (20%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGE---------RGISGAIGPPGPRGDIG 1619 PA PN + G G PGPAG GA G G RG+ G+ G PG G G Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPG 552 Query: 1620 PPGPQG------PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP--- 1670 PPG QG PPGP GP G PG G G KG+ G PG G G PG PGP GP Sbjct: 553 PPGSQGESGRPGPPGPSGPRGQ--PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610 Query: 1671 ---MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 1727 GP G G TG G G GPPGP G G PG GP G+ GKPG+ G G +G G Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670 Query: 1728 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP-- 1785 G +GD + L G P + + GPPGPPG Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAG----------PPGPEGGKGAAGPPGPPGAAG 720 Query: 1786 -------PGSAGARGEPGPGGRPGFPGTPGMQ---------------GPPGERGLPGEKG 1823 PG G G PGP G G PG PG GPPG G PG+KG Sbjct: 721 TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG 780 Query: 1824 ERG-------------------TGSSGPRGLPGPPG----PQGESRTGPPGSTGSRGPPG 1860 E G TG GP G PG PG P G+ G PG G GPPG Sbjct: 781 EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840 Query: 1861 PPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 1898 G PG SG GPPGP G P G+PG+ Sbjct: 841 VAGPPGGSGPAGPPGPQGVKGERGSPGGP-GAAGFPGA 877 Score = 229 bits (583), Expect = 3e-59 Identities = 143/353 (40%), Positives = 167/353 (47%), Gaps = 47/353 (13%) Query: 1568 CPAFPNSCTCTQDSVGPPGP---PGPAGGPGAKGPRGERGISGAIGPPGPRG-------- 1616 CP P + T + GP GP PGP G PG G G G G+ G PGP G Sbjct: 88 CPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG 147 Query: 1617 -----------DI----------GPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGL 1655 D+ G PGP GPPGP GP G S G G G G G PG Sbjct: 148 PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS--GHPGSPGSPGYQGPPGE 205 Query: 1656 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD 1715 PG+ G G PGPPG +GP G GKDG G G PG G PG PG+ GP+G PG PG Sbjct: 206 PGQAGPSGPPGPPGAIGPSGP---AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGM 262 Query: 1716 HGRPGPSGLKGEKGDRG--DIASQNMM---RAVARQVCEQLISGQMNRFNQMLNQIPNDY 1770 G G G GEKG+ G + +N + + + G+ R Sbjct: 263 KGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322 Query: 1771 QSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GS 1829 +R G PGPPGPPG+AG G PG G G G+PG G PG+RG PG +G G G Sbjct: 323 DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382 Query: 1830 SGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 1878 GP G+ G PG +GE G PG G+RGPPGP G G G+RG G PG Sbjct: 383 PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435 Score = 211 bits (536), Expect = 7e-54 Identities = 123/292 (42%), Positives = 139/292 (47%), Gaps = 65/292 (22%) Query: 1583 GPPGPPGPAGGPGAKGPRGE------RGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNGL 1635 GPPG PGP G PG +G +GE G+SG GPPGP+G G G G PG G P Sbjct: 960 GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019 Query: 1636 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 1695 +PG G G KGD GE G PG G PG PGPPGP+GP G G G+ G GP G PGP Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPA 1079 Query: 1696 GSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQ 1755 GS G+PG GP G G+ G+ G +G+KG +G G+ Sbjct: 1080 GSRGAPGPQGPRGDKGETGER---GAAGIKGHRGFPGN---------------------- 1114 Query: 1756 MNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE 1815 PG PG PGP G GA G PGP G G G GPPG+ Sbjct: 1115 ---------------------PGAPGSPGPAGQQGAIGSPGPAGP---RGPVGPSGPPGK 1150 Query: 1816 RGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPG 1866 G G GP G PGP G +GE G PG G GPPGPPG PG Sbjct: 1151 DGTSGH--------PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194 Score = 205 bits (521), Expect = 4e-52 Identities = 138/371 (37%), Positives = 163/371 (43%), Gaps = 60/371 (16%) Query: 1556 CCDIPSRRDEGKCP----AFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP 1611 C DI E CP F C +V P P P P +GP+G +G G G Sbjct: 62 CDDIICDDQELDCPNPEIPFGECC-----AVCPQPPTAPTRPPNGQGPQGPKGDPGPPGI 116 Query: 1612 PGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 1671 PG GD G PG G PG GP G+ G Q + GL G PGP Sbjct: 117 PGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPA 176 Query: 1672 GP---------------PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGP------SGKP 1710 GP PG G+ G G G GP GPPG PG+ G +GP SG+P Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236 Query: 1711 GKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY 1770 G+PG+ G PGP G+KG G G R + E+ +G + N +P + Sbjct: 237 GRPGERGLPGPPGIKGPAGIPG-FPGMKGHRGFDGRNGEKGETGAPGLKGE--NGLPGEN 293 Query: 1771 -----QSSRNQPGPPGPPGPPGSAGARGE------------PGPGGRPGFPGTPGMQ--- 1810 R PG G PG PG+AGARG PGP G GFPG+PG + Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353 Query: 1811 ---GPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGN 1867 G PG G PG++GE G G G GPPGP G + G PG G GP G PG PG Sbjct: 354 GPAGSPGSNGAPGQRGE--PGPQGHAGAQGPPGPPGIN--GSPGGKGEMGPAGIPGAPGL 409 Query: 1868 SGIRGPPGPPG 1878 G RGPPGP G Sbjct: 410 MGARGPPGPAG 420 Score = 148 bits (373), Expect = 6e-35 Identities = 78/156 (50%), Positives = 84/156 (53%), Gaps = 10/156 (6%) Query: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPG 1639 S G PG PG G PG GP G+ G G GP GP G GP G +G PGPQGP G G Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETG 1098 Query: 1640 EQGRQGMKGDAGEPGLPGRTGTP---------GLPGPPGPMGPPGDRGFTGKDGAMGPRG 1690 E+G G+KG G PG PG G+P G PGP GP GP G G GKDG G G Sbjct: 1099 ERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPG 1158 Query: 1691 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 1726 P GPPG G+ G G G PG PG G PGP G G Sbjct: 1159 PIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194 Score = 141 bits (356), Expect = 5e-33 Identities = 93/239 (38%), Positives = 108/239 (45%), Gaps = 54/239 (22%) Query: 1649 DAGEPGLPGRTGTPGLPGPP-GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPS 1707 D P +P P PP P PP +G P+GP G PG PG PG G Sbjct: 73 DCPNPEIPFGECCAVCPQPPTAPTRPPNGQG---------PQGPKGDPGPPGIPGRNGDP 123 Query: 1708 GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 1767 G PG+PG G PGP G +CE +G N Q + Sbjct: 124 GIPGQPGSPGSPGPPG-----------------------ICESCPTGPQNYSPQYDSY-- 158 Query: 1768 NDYQSS------RNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 1821 D +S PGP GPPGPPG PG G PG PG+PG QGPPGE PG+ Sbjct: 159 -DVKSGVAVGGLAGYPGPAGPPGPPGP------PGTSGHPGSPGSPGYQGPPGE---PGQ 208 Query: 1822 KGERGTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 1879 G +G GP G GP GP G + +G PG G RG PGPPG G +GI G PG G+ Sbjct: 209 AGP--SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH 265 Score = 139 bits (349), Expect = 3e-32 Identities = 77/171 (45%), Positives = 87/171 (50%), Gaps = 30/171 (17%) Query: 1583 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 1642 G PGPPGP G G G RGE G +G G PGP G G PGPQGP G +G G E+G Sbjct: 1047 GHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETG-----ERG 1101 Query: 1643 RQGMKGDAGEPGLPGRTGTPGLPG---------------PPGPMGPPGDRGFTGKDGAMG 1687 G+KG G PG PG G+PG G P GP GPPG G +G G +G Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIG 1161 Query: 1688 PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP----------SGLKGEK 1728 P GP G G GS G G G+PG PG G PGP +G+ GEK Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212 Score = 96.7 bits (239), Expect = 2e-19 Identities = 56/128 (43%), Positives = 59/128 (46%), Gaps = 23/128 (17%) Query: 1569 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISG--------------------- 1607 PA P S G PGP GP G G G RG GI G Sbjct: 1069 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG 1128 Query: 1608 AIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 1667 AIG PGP G GP GP GPPG G +G PG G G +G+ GE G G G PG PGP Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPGKDGTSG--HPGPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186 Query: 1668 PGPMGPPG 1675 PGP G PG Sbjct: 1187 PGPPGAPG 1194 Score = 87.4 bits (215), Expect = 1e-16 Identities = 50/126 (39%), Positives = 60/126 (47%), Gaps = 17/126 (13%) Query: 1767 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG-----PPGERGLPGE 1821 P + + GP G PGPPG G G+PG G+PG PG+PG G P G + + Sbjct: 95 PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ 154 Query: 1822 KG----ERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 1877 + G G G PGP GP G PPG G+ G PG PG PG +GPPG P Sbjct: 155 YDSYDVKSGVAVGGLAGYPGPAGPPG-----PPGPPGTSGHPGSPGSPG---YQGPPGEP 206 Query: 1878 GYCDSS 1883 G S Sbjct: 207 GQAGPS 212 Score = 56.6 bits (135), Expect = 2e-07 Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 7/65 (10%) Query: 1827 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 1886 T + P GP GP+G+ GPPG G G PG PG+PG+ G PGPPG C+S C Sbjct: 93 TAPTRPPNGQGPQGPKGDP--GPPGIPGRNGDPGIPGQPGSPG---SPGPPGICES--CP 145 Query: 1887 SIPYN 1891 + P N Sbjct: 146 TGPQN 150 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.135 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97,185,402 Number of Sequences: 37866 Number of extensions: 6593196 Number of successful extensions: 174687 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 538 Number of HSP's successfully gapped in prelim test: 1511 Number of HSP's that attempted gapping in prelim test: 29513 Number of HSP's gapped (non-prelim): 27440 length of query: 1899 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1782 effective length of database: 13,817,196 effective search space: 24622243272 effective search space used: 24622243272 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.