BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo sapiens] (3063 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 6192 0.0 gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 3858 0.0 gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 1267 0.0 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 439 e-122 gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 427 e-119 gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 387 e-107 gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 386 e-106 gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 383 e-105 gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 383 e-105 gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 382 e-105 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 352 4e-96 gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 342 3e-93 gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 342 4e-93 gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s... 333 2e-90 gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 278 8e-74 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 264 9e-70 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 259 2e-68 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 259 3e-68 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 254 7e-67 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 254 7e-67 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 254 7e-67 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 254 9e-67 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 253 2e-66 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 253 2e-66 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 253 2e-66 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 253 2e-66 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 253 2e-66 gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s... 253 2e-66 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 252 3e-66 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 252 5e-66 >gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo sapiens] Length = 3063 Score = 6192 bits (16065), Expect = 0.0 Identities = 3063/3063 (100%), Positives = 3063/3063 (100%) Query: 1 MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVD 60 MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVD Sbjct: 1 MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVD 60 Query: 61 PTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKP 120 PTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKP Sbjct: 61 PTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKP 120 Query: 121 VEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG 180 VEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG Sbjct: 121 VEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG 180 Query: 181 VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVG 240 VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVG Sbjct: 181 VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVG 240 Query: 241 FPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVA 300 FPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVA Sbjct: 241 FPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVA 300 Query: 301 NFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP 360 NFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP Sbjct: 301 NFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP 360 Query: 361 VTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIME 420 VTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIME Sbjct: 361 VTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIME 420 Query: 421 KTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQIS 480 KTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQIS Sbjct: 421 KTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQIS 480 Query: 481 LVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN 540 LVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN Sbjct: 481 LVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN 540 Query: 541 VPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVE 600 VPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVE Sbjct: 541 VPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVE 600 Query: 601 DFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVF 660 DFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVF Sbjct: 601 DFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVF 660 Query: 661 SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE 720 SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE Sbjct: 661 SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE 720 Query: 721 EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLE 780 EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLE Sbjct: 721 EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLE 780 Query: 781 NLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGK 840 NLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGK Sbjct: 781 NLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGK 840 Query: 841 VKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGT 900 VKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGT Sbjct: 841 VKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGT 900 Query: 901 TLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT 960 TLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT Sbjct: 901 TLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT 960 Query: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP Sbjct: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020 Query: 1021 GKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080 GKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS Sbjct: 1021 GKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080 Query: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN Sbjct: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140 Query: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADI 1200 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADI Sbjct: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADI 1200 Query: 1201 VLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKK 1260 VLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKK Sbjct: 1201 VLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKK 1260 Query: 1261 SLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320 SLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS Sbjct: 1261 SLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320 Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK Sbjct: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380 Query: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTV 1440 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTV Sbjct: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTV 1440 Query: 1441 LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA 1500 LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA Sbjct: 1441 LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA 1500 Query: 1501 TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR 1560 TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR Sbjct: 1501 TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR 1560 Query: 1561 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS 1620 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS Sbjct: 1561 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS 1620 Query: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS Sbjct: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680 Query: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS Sbjct: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 Query: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT Sbjct: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800 Query: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 1860 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL Sbjct: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 1860 Query: 1861 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 1920 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG Sbjct: 1861 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 1920 Query: 1921 DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI 1980 DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI Sbjct: 1921 DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI 1980 Query: 1981 VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS 2040 VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS Sbjct: 1981 VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS 2040 Query: 2041 LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE 2100 LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE Sbjct: 2041 LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE 2100 Query: 2101 DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME 2160 DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME Sbjct: 2101 DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME 2160 Query: 2161 AFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220 AFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF Sbjct: 2161 AFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220 Query: 2221 CVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280 CVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE Sbjct: 2221 CVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280 Query: 2281 GPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFN 2340 GPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFN Sbjct: 2281 GPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFN 2340 Query: 2341 KVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGN 2400 KVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGN Sbjct: 2341 KVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGN 2400 Query: 2401 TRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGV 2460 TRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGV Sbjct: 2401 TRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGV 2460 Query: 2461 ADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPG 2520 ADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPG Sbjct: 2461 ADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPG 2520 Query: 2521 FKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTII 2580 FKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTII Sbjct: 2521 FKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTII 2580 Query: 2581 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV 2640 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV Sbjct: 2581 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV 2640 Query: 2641 KTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAA 2700 KTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAA Sbjct: 2641 KTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAA 2700 Query: 2701 FQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGA 2760 FQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGA Sbjct: 2701 FQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGA 2760 Query: 2761 KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLP 2820 KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLP Sbjct: 2761 KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLP 2820 Query: 2821 GRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH 2880 GRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH Sbjct: 2821 GRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH 2880 Query: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ 2940 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ Sbjct: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ 2940 Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP Sbjct: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000 Query: 3001 GPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP 3060 GPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP Sbjct: 3001 GPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP 3060 Query: 3061 GSG 3063 GSG Sbjct: 3061 GSG 3063 >gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo sapiens] Length = 1899 Score = 3858 bits (10006), Expect = 0.0 Identities = 1876/1879 (99%), Positives = 1877/1879 (99%) Query: 1185 ILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS 1244 I + GMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS Sbjct: 21 IEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS 80 Query: 1245 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG Sbjct: 81 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 140 Query: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL Sbjct: 141 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 200 Query: 1365 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG 1424 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG Sbjct: 201 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG 260 Query: 1425 GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD 1484 GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD Sbjct: 261 GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD 320 Query: 1485 VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 1544 VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT Sbjct: 321 VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 380 Query: 1545 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 1604 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE Sbjct: 381 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 440 Query: 1605 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT 1664 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT Sbjct: 441 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT 500 Query: 1665 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI 1724 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI Sbjct: 501 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI 560 Query: 1725 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 1784 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR Sbjct: 561 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 620 Query: 1785 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL Sbjct: 621 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680 Query: 1845 NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 1904 NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ Sbjct: 681 NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 740 Query: 1905 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY 1964 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY Sbjct: 741 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY 800 Query: 1965 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP 2024 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP Sbjct: 801 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP 860 Query: 2025 RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP 2084 RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP Sbjct: 861 RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP 920 Query: 2085 LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144 LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL Sbjct: 921 LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL 980 Query: 2145 GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY 2204 GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY Sbjct: 981 GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY 1040 Query: 2205 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP 2264 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP Sbjct: 1041 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP 1100 Query: 2265 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI 2324 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI Sbjct: 1101 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI 1160 Query: 2325 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK 2384 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK Sbjct: 1161 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK 1220 Query: 2385 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA 2444 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA Sbjct: 1221 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA 1280 Query: 2445 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA 2504 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA Sbjct: 1281 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA 1340 Query: 2505 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP 2564 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP Sbjct: 1341 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP 1400 Query: 2565 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK 2624 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK Sbjct: 1401 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK 1460 Query: 2625 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG 2684 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG Sbjct: 1461 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG 1520 Query: 2685 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD 2744 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD Sbjct: 1521 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD 1580 Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE Sbjct: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS Sbjct: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700 Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN Sbjct: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 1760 Query: 2925 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG 2984 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG Sbjct: 1761 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG 1820 Query: 2985 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC 3044 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC Sbjct: 1821 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC 1880 Query: 3045 DSSQCASIPYNGQGYPGSG 3063 DSSQCASIPYNGQGYPGSG Sbjct: 1881 DSSQCASIPYNGQGYPGSG 1899 Score = 490 bits (1262), Expect = e-138 Identities = 336/1084 (30%), Positives = 527/1084 (48%), Gaps = 70/1084 (6%) Query: 127 KTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSS 186 + E +C A D+V LVDGSWS+GR NF+ + FI+ +V FDIG ++ ++ + QYS Sbjct: 22 EAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSG 81 Query: 187 DTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAI 246 D RTE+ LN + + LL A+ +PYKGGNT+TG A++++ + F AG R K+ + Sbjct: 82 DPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGV 141 Query: 247 IITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIV 306 +ITDGKSQD+VE P+++L++ GVE+F++GIK AD ELK IA+ P H +NVA+F+++ Sbjct: 142 LITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLS 201 Query: 307 DIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKV 366 I +++ +C+ V G +E PSNL+ E + + +++W P V YKV Sbjct: 202 RIVDDLTINLCNS--------VKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKV 253 Query: 367 ILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMK 426 P++ G RQ +T+T+ ++DL +TEY ++V ++ SEP+ EKT P+ Sbjct: 254 EYYPVSGGKRQEFYVSRMETSTV-LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP 312 Query: 427 -VQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYS 485 V + + + G + I ++ V+ K + P + L Sbjct: 313 VVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLV 372 Query: 486 RDPHTEFTLKKFTKVEDII-EAIN----TFPYRGGSTNTGKAMTYVREKIF---VPSKGS 537 P+TE+ + + D+ E + T P + +T+ +F VP K Sbjct: 373 --PNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK-V 429 Query: 538 RSNVPKVMILITDGKSSDAFR-DPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHV 596 R + + D K + R + + L++ + AV E E SPP Sbjct: 430 RKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE---SPPVTAQ- 485 Query: 597 FTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAG 656 E T+ + ++ + + + D S+V+ Y + W+P G Sbjct: 486 --------------ETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLY--RITWAPFG 529 Query: 657 ENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYED-GFSIPLAG 715 + D++ + ++V +L P T+Y V++TA Y D S L G Sbjct: 530 SS--------------DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 575 Query: 716 EE------TTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAG-GESREV 768 E TT+ K PRNL+V + T++S + W A GRV +YRI Y+P G G + Sbjct: 576 SERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 635 Query: 769 TTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTS 828 T Q L+ L PDT Y ++V Y G G +TG T+ + R+LRV DP+TS Sbjct: 636 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL-NTVRNLRVYDPSTS 694 Query: 829 TMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYA 888 T+ + W A G +QY + Y P AGG + V + G+T +L+ L+ T Y ++V +Y Sbjct: 695 TLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 754 Query: 889 SGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDT 948 G G G TL RG +++ + T S+ W APG V YRV + + + Sbjct: 755 EGDGGRTSDTGRTL-MRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 813 Query: 949 GEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEET 1008 +P + +E L P+T Y +++ A YS GEG P T + L+V ET Sbjct: 814 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 873 Query: 1009 ENTMRVTWKPAPGKVVNYRVVYRPH-GRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLP 1067 N++ V W A G V YR++Y P G VP + +L+ LQP T Y ITV+ Sbjct: 874 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 933 Query: 1068 IYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDD 1127 +Y+ G+G G+G T P+N+ SD + FRV+W+P+P V GYK+ + P G + Sbjct: 934 VYEDGDGGHLTGNGRTVG-LLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSN 992 Query: 1128 RRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILS 1187 + E VG + L L TTY VNV+ +D G S PL Q T + T + Sbjct: 993 EPM-EAFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQ 1050 Query: 1188 SGME 1191 G + Sbjct: 1051 IGWD 1054 Score = 426 bits (1094), Expect = e-118 Identities = 326/1094 (29%), Positives = 512/1094 (46%), Gaps = 61/1094 (5%) Query: 309 QNEIISQVCSGVDEQLGELVSGEE--VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKV 366 + E + V S V+++ E + G E + P +L +V + + W P TGY + Sbjct: 283 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYIL 341 Query: 367 ILTPM--TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424 P+ T +R + +GP + + DL +TEY ++V A+ +SEP+++ E T P Sbjct: 342 SYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLP 401 Query: 425 MKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQY 484 + R D+K L D ++S + F E + P +V+ +V+Y Sbjct: 402 LP------RPQDLK-----LRDVTHST-------MNVFWEPV-------PGKVRKYIVRY 436 Query: 485 SRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKV 544 + P + + + E + F + + A+ E V ++ + VP Sbjct: 437 -KTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVS-AVHDEGESPPVTAQETTRPVPAP 494 Query: 545 MILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSE-LEAIASPPAETHVFTVEDFD 603 L +S+ FR SDV ++ + S+ +E I + T VF + + Sbjct: 495 TNLKITEVTSEGFRG-TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPN 553 Query: 604 AFQRISF------ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAG 656 +S E + E+ L + +A P++L TS W PA Sbjct: 554 TIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPAS 613 Query: 657 ENVFSYHITYKEAAGD-DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAG 715 V Y ITY+ + G+ +E T SVVL LKP+T Y + V++ Y DG + G Sbjct: 614 GRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTG 673 Query: 716 EETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR 775 T+ + RNL+V D +T + + W A G +Y++ Y P AGG V P N Sbjct: 674 RGKTKPLNTV-RNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTN 732 Query: 776 RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWS 835 L NL PDT Y V+V+P Y G G T + +RG R+++V +PT +++ + W Sbjct: 733 YAILRNLQPDTSYTVTVVPVYTEGDGGR-TSDTGRTLMRGLARNVQVYNPTPNSLDVRWD 791 Query: 836 GAPGKVKQYLVTYTPVAGGETQE-VTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDA 894 APG V QY V Y+PV G E + V G+T L+ L T Y++++ ALY+ G G+ Sbjct: 792 PAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNP 851 Query: 895 LFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLP 954 +G TL G P++L T S+ W A G V+ YR+ + D +P Sbjct: 852 SPAQGRTLPRSG-PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP 910 Query: 955 EDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRV 1014 + +++ LQP+T Y+I+V A Y G+G LTG+ T + + + +E RV Sbjct: 911 GRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRV 970 Query: 1015 TWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEG 1074 +W P+P V+ Y++VY+P G + M A V +TS L L P TTYD+ V Y G Sbjct: 971 SWDPSPSPVLGYKIVYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLS 1029 Query: 1075 KLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELV 1134 GTT + + +LKT +F V W P Y++ P D R E+ Sbjct: 1030 VPLTDQGTTL--YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSP-ADGTRGQEIT 1085 Query: 1135 VGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTV---------MPI 1185 V + + L T Y V VF E + +E TT+ T P Sbjct: 1086 VRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPT 1145 Query: 1186 LSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFD-IGPKRVQIALAQYS 1244 + + A+ADIV L D SWSIG NF V FI V FD I P +Q++ QYS Sbjct: 1146 IPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYS 1205 Query: 1245 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304 + ++E++LN + DK L A+ N+ Y+GGNT TG AL FI+++ ++GMR K+ Sbjct: 1206 DEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVL 1265 Query: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364 V++TDG+SQD+V+ + ++ G +F +G+ + D EL IA+ P + H + V DFES Sbjct: 1266 VVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESF 1325 Query: 1365 SRIVDDLTINLCNS 1378 +I D+L +C + Sbjct: 1326 EKIEDNLITFVCET 1339 Score = 171 bits (434), Expect = 8e-42 Identities = 122/370 (32%), Positives = 182/370 (49%), Gaps = 28/370 (7%) Query: 352 LNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMT 411 + W+P + T Y++ L+P G+R ++V T+ LS DT+Y ++V Sbjct: 1058 VKWSPHRA-ATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNL 1115 Query: 412 SSEPISIMEKTQ-------------PMKVQVECSRGV--DIKADIVFLVDGSYSIGIANF 456 +S+ E T P + +R V KADIVFL D S+SIG NF Sbjct: 1116 EGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNF 1175 Query: 457 VKVRAFLEVLVKSF-EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGG 515 KV F+ V F EISP +Q+S VQYS + +EF L + + A+ YRGG Sbjct: 1176 NKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGG 1235 Query: 516 STNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVG 575 +T TGKA+T+++EK+ G R NVPKV++++TDG+S D + A+ ++ S +F VG Sbjct: 1236 NTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVG 1295 Query: 576 VKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPP 635 V D +EL IAS P+E HVF V+DF++F++I L +C I Y P Sbjct: 1296 VADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSP 1355 Query: 636 --KDLSFSEVTSYGFKTNWSPAGEN----VFSYHITYKEAAGDDEVTVVE----PASSTS 685 K L +T F + + E+ +S + K A + + P S T Sbjct: 1356 GFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTI 1415 Query: 686 VVLSSLKPET 695 ++L L PET Sbjct: 1416 ILLFRLLPET 1425 Score = 162 bits (411), Expect = 4e-39 Identities = 103/295 (34%), Positives = 154/295 (52%), Gaps = 7/295 (2%) Query: 29 SDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPET 88 +DL I +T + W+ P YR+ + P +E T+ S T + L P+T Sbjct: 1044 TDLKTYQIGWDTFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDT 1102 Query: 89 EYVVTITSYDEVEES--VPVIGQLTIQ-TGSSTKPVEKKPGKT--EIQKCSVSAWTDLVF 143 +Y VT+ E V V T++ T + T+P P T + A D+VF Sbjct: 1103 DYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVF 1162 Query: 144 LVDGSWSVGRNNFKYILDFIAALVSAFD-IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDE 202 L D SWS+G +NF ++ FI V FD I +V VQYS + ++EF LN Y + Sbjct: 1163 LTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKAL 1222 Query: 203 LLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPAR 262 L A++ I Y+GGNT TG A+ ++ + T +G R PKV +++TDG+SQDEV+ A Sbjct: 1223 ALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAAL 1282 Query: 263 ELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVC 317 ++ G VF +G+ D EL IAS PS HVF V +F++ I++ +I+ VC Sbjct: 1283 VIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVC 1337 Score = 57.8 bits (138), Expect = 2e-07 Identities = 30/85 (35%), Positives = 46/85 (54%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 +++ PS+L + +SW P D + Y++ P + G +EF +S T T+L + Sbjct: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279 Query: 84 LVPETEYVVTITSYDEVEESVPVIG 108 L PETEYVV + S E E S P+ G Sbjct: 280 LKPETEYVVNVYSVVEDEYSEPLKG 304 Score = 46.6 bits (109), Expect = 4e-04 Identities = 24/24 (100%), Positives = 24/24 (100%) Query: 1 MRSRLPPALAALGAALLLSSIEAE 24 MRSRLPPALAALGAALLLSSIEAE Sbjct: 1 MRSRLPPALAALGAALLLSSIEAE 24 Score = 44.7 bits (104), Expect = 0.001 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 6/85 (7%) Query: 27 PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDG-PT--KEFTLSASTTETLLSE 83 P LN + T+H+ W +PV GY ++ P D PT KE L + + L++ Sbjct: 312 PVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTD 370 Query: 84 LVPETEYVVTITS--YDEVEESVPV 106 LVP TEY VT+ + +D E V V Sbjct: 371 LVPNTEYAVTVQAVLHDLTSEPVTV 395 Score = 37.7 bits (86), Expect = 0.18 Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 1/82 (1%) Query: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 L + + +A P +L N++ + W + YRIT P+T +G + T+ Sbjct: 580 LPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGG 639 Query: 75 STTETLLSELVPETEYVVTITS 96 +L +L P+T Y +T++S Sbjct: 640 RQNSVVLQKLKPDTPYTITVSS 661 Score = 37.4 bits (85), Expect = 0.23 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 32 NFKIIDE--NTVHMSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPET 88 N ++ E N++ ++W P+ YRI PT P E+ T+ +L L P+T Sbjct: 866 NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 925 Query: 89 EYVVTITSYDE 99 Y +T+ + E Sbjct: 926 PYKITVIAVYE 936 Score = 34.3 bits (77), Expect = 1.9 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 1/85 (1%) Query: 27 PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVP 86 PP +++ +SW P++GY+I P E + T+ T L L P Sbjct: 954 PPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYT-LHNLNP 1012 Query: 87 ETEYVVTITSYDEVEESVPVIGQLT 111 T Y V + + + SVP+ Q T Sbjct: 1013 STTYDVNVYAQYDSGLSVPLTDQGT 1037 Score = 32.3 bits (72), Expect = 7.4 Identities = 26/116 (22%), Positives = 45/116 (38%), Gaps = 1/116 (0%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSEL 84 V P++L + +W + YRIT P E L+ + L Sbjct: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 550 Query: 85 VPETEYVVTITS-YDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 P T Y V+IT+ Y + ES +IG +T+ + P ++ + ++ T Sbjct: 551 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLT 606 >gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] Length = 1796 Score = 1267 bits (3278), Expect = 0.0 Identities = 653/1459 (44%), Positives = 899/1459 (61%), Gaps = 54/1459 (3%) Query: 1627 QTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYR 1686 ++L S V ++ +A T P PT L +EVT+ F W H +V YR Sbjct: 328 ESLTRTLCSRVEEQDREIKASAHAITGP---PTELITSEVTARSFMVNWTHAPGNVEKYR 384 Query: 1687 ITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPI 1746 + + P E +++G ++ V +NL T Y++++ AIY + S+ L G+E TL + Sbjct: 385 VVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYA-HTASEGLRGTETTLAL 443 Query: 1747 LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTG--EGNEQTTTIGGR 1804 +L +Y+ T NS+ VKWD G Y I Y P T G+E+ IG Sbjct: 444 PMAS-------DLLLYDVTENSMRVKWDAVPG-ASGYLILYAPLTEGLAGDEKEMKIGET 495 Query: 1805 QNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRW 1864 + L L P+T YT+TV +++ + +TG+ T L+ RNLR+ + +++ + W Sbjct: 496 HTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTW 555 Query: 1865 DHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGR 1924 D Y++ Y A G V + T + L+ L P T YT+ + +Y EG Sbjct: 556 DPTSRQINGYRIVYNNADGTEINEVEVDPITTFP-LKGLTPLTEYTIAIFSIYDEGQSEP 614 Query: 1925 TSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPG 1984 + T + +++ T +S V W P +++++ PV G + E ++ Sbjct: 615 LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674 Query: 1985 NTRMVHLERLIPDTLYSVNLVALYSDG-EGNPSPAQGRTLP------------------- 2024 V +E L P T Y V+L+A+ DG E A G TL Sbjct: 675 QDSHV-IEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSV 733 Query: 2025 -RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEY---TTVPGRRNNV 2080 ++G RNL V ETT+SL V WD +D VQQ+R+ Y GDP +E VPG +NN+ Sbjct: 734 FQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNL 793 Query: 2081 ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSP 2140 +L+PL PDT YK+TV +Y DG+G ++ G+T+ PQN+ +S+EWY R R++WDP Sbjct: 794 LLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853 Query: 2141 SPVLGYKIVYKPVGSNEP-MEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTD 2198 SPV GY+IVYKPV P +E FVG ++ + + NL Y+V ++A SG S LT Sbjct: 854 SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913 Query: 2199 QGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHC 2258 TL+L VT+L+ + + C W HR AT+YR+ + + QE TV G T HC Sbjct: 914 MVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHC 973 Query: 2259 FTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCK 2318 F GL PD++Y ++V+ + +EGP VS+ E T PT PT PPT IPPA++VCK Sbjct: 974 FYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPT------IPPAKEVCK 1027 Query: 2319 GAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKL 2378 AKAD+VF+ D SWSIGD+NFNK++ F+++TVG ++I G QV+ VQ++D+ ++EFKL Sbjct: 1028 AAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKL 1087 Query: 2379 NTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQ 2438 N Y K L A+++I Y+GGNT+TGKA+ ++++ + T ESG R+ +PKV+VV+TDGRSQ Sbjct: 1088 NAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQ 1147 Query: 2439 DEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLIT 2498 D+V K + +Q G+S+F +GVAD DY+EL +I SKPS RHVF VDDF++F+KIED LIT Sbjct: 1148 DDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELIT 1207 Query: 2499 FVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKN 2558 FVCETA+++CP+++ DG GFKM+E + L EK+F+SV+GVS+E G+F + Y++ K+ Sbjct: 1208 FVCETASATCPVVHKDGIDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNVFPCYQLHKD 1267 Query: 2559 AFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKT 2618 A V+QPT LHP GLP YTI LFR+LP+TP +PFA+W+I +++ P VGVI D KT Sbjct: 1268 ALVSQPTRYLHPEGLPSDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNGGKT 1327 Query: 2619 LSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAG 2678 L++FN D G+ QTVTF+ E++ +FYGSFHK+HIVV+ VK+ IDC ++ EK + + Sbjct: 1328 LTYFNYDQSGDFQTVTFEGPEIRKIFYGSFHKLHIVVSETLVKVVIDCKQVGEKAMNASA 1387 Query: 2679 NITTDGYEILGKLLKGE---RKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAF 2735 NIT+DG E+LGK+++ SA FQ+Q FDIVCS W + D+CC++P RD+ CP Sbjct: 1388 NITSDGVEVLGKMVRSRGPGGNSAPFQLQMFDIVCSTSWANTDKCCELPGLRDDESCPDL 1447 Query: 2736 PNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 2795 P+SC+C++ + GP GP GGPG +GP+G++G G GP GPRG+IG PGPQGPPGPQG Sbjct: 1448 PHSCSCSETNEVALGPAGPPGGPGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQGPPGPQG 1507 Query: 2796 PNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP 2855 P+GLSI G G G KG+ G+ GLPG G PG G PG G PG RG GKDG+ GP GP Sbjct: 1508 PSGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPGRDGSPGQRGLPGKDGSSGPPGP 1567 Query: 2856 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915 PGP G PG+PGV G +G G G G PG G KGE+G+RGD+ SQ M+R+VARQVCEQL Sbjct: 1568 PGPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERGERGDLQSQAMVRSVARQVCEQL 1627 Query: 2916 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG 2975 I M R+ +LNQIP+ S R GPPG PG PGS GA GE GP G PGFPG G+ G Sbjct: 1628 IQSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPG 1687 Query: 2976 PPGERGLPGEKGER---GTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNS 3032 PGERGL G KGE+ G G+ GPRG PGP GP GESR G PG GS GP GPPG G Sbjct: 1688 TPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVP 1747 Query: 3033 GIRGPPGPPGYCDSSQCAS 3051 G +GP G PGYCD S C++ Sbjct: 1748 GPQGPSGQPGYCDPSSCSA 1766 Score = 600 bits (1546), Expect = e-171 Identities = 360/969 (37%), Positives = 540/969 (55%), Gaps = 50/969 (5%) Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149 P L+ + + S +++W+ G+ GYK+ PT + +L + +++ L Sbjct: 33 PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKT-NQLNLQNTATKAIIQGLMP 91 Query: 1150 GTTYKVNVFGMFDGGESSPLVGQ----EMTTLSDTTV-MPILSSG------------MEC 1192 Y V + ES P GQ ++ D + ++ G C Sbjct: 92 DQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVKFVC 151 Query: 1193 LTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQ 1252 T A ADIV+LVDGSWSIGR NFR VR F+ +V FD+G ++ +I LAQYSGDPR EW Sbjct: 152 QTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWH 211 Query: 1253 LNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKS 1312 LNA K +++AV NLPYKGGNTLTG+ALN+I + +F+ +AG R KIG+LITDGKS Sbjct: 212 LNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKS 271 Query: 1313 QDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT 1372 QDD+ PS+ L++ GVELFAIG+KNAD EL+ IA++PD TH YNVA+F+ + +V+ LT Sbjct: 272 QDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLT 331 Query: 1373 INLCNSVKGPG-DLEA--------PSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS 1423 LC+ V+ +++A P+ L+ SE T RSF V+WT +V++Y+V YYP Sbjct: 332 RTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTR 391 Query: 1424 GGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVS-LNI 1482 GGK E V +STVLK+L TEY + V+++ SE L+GTE TL +P+ S L + Sbjct: 392 GGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLL 451 Query: 1483 YDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA 1542 YDV +M V+W V GA+GY++ Y P+ + KE+++G T D++L+ L+PNTEY Sbjct: 452 YDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT 511 Query: 1543 VTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKT 1602 VTV A+ + S+PVT +E TL L P++L++ +V ++ + W+P ++ Y + Y Sbjct: 512 VTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNN 571 Query: 1603 PE-EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNL 1661 + ++ EVEVD T+ LK L T YT+++ +++DEG+S P+T TT VPA L Sbjct: 572 ADGTEINEVEVD-PITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYL 630 Query: 1662 KITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYE 1721 +I EVT++ FR TW ++D L+++ W P E +L ++++ V E L P T YE Sbjct: 631 EIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYE 690 Query: 1722 VSITAIYPDESESDDLIGSERTL------PILT-------TQAPKSGPRNLQVYNATSNS 1768 VS+ A+ D SES+ + TL P T T ++G RNL V + T++S Sbjct: 691 VSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSS 750 Query: 1769 LTVKWDPASGRVQKYRITYQPSTGEGNEQ---TTTIGGRQNSVVLQKLKPDTPYTITVSS 1825 L VKWD + VQ++R+TY + G+ E+ T + G QN+++L+ L PDT Y +TV+ Sbjct: 751 LRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTP 810 Query: 1826 LYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAP-AAGG 1884 +Y DGEG ++ GKT P + +NLRV + + L + WD + Y++ Y P + G Sbjct: 811 IYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPG 870 Query: 1885 PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYN 1944 P + + N ++ NL Y V + G + +TL G+ N+Q + Sbjct: 871 PTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVT-NLQAKH 929 Query: 1945 PTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNL 2004 SL W YRVV + + ES V G TR L PD+ Y +++ Sbjct: 930 VEMTSLCAHWQ-VHRHATAYRVVIESLQDRQKQESTVGGGTTRHC-FYGLQPDSEYKISV 987 Query: 2005 VALYSDGEG 2013 + EG Sbjct: 988 YTKLQEIEG 996 Score = 420 bits (1079), Expect = e-116 Identities = 313/1027 (30%), Positives = 481/1027 (46%), Gaps = 90/1027 (8%) Query: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64 LPP LA + + ++ +V PP+ L + +I +++ +SW P GY++ V PT+ Sbjct: 13 LPPFLAIV---YFCTIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG 69 Query: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTI---QTGSSTKPV 121 G T + L + T+ ++ L+P+ Y V I +Y++ +ES P GQ I + KP Sbjct: 70 GKTNQLNLQNTATKAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPR 129 Query: 122 EK--------KPGKTEIQK--CSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFD 171 K +P E K C A D+V LVDGSWS+GR NF+ + F+ LV+AFD Sbjct: 130 VKVVDRGNGSRPSSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFD 189 Query: 172 IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTF 231 +G EKTR+G+ QYS D R E++LN + +DE++ A++ +PYKGGNT+TG A++Y+ +N+F Sbjct: 190 VGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSF 249 Query: 232 TESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTP 291 AG+R G K+ I+ITDGKSQD++ P+R LR GVE+F++G+K AD EL++IAS P Sbjct: 250 KPEAGSRTGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEP 309 Query: 292 SLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGEL-VSGEEVVEPPSNLIAMEVSSKYV 350 HV+NVA FD + + + +CS V+EQ E+ S + PP+ LI EV+++ Sbjct: 310 DSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSF 369 Query: 351 KLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM 410 +NW +P V Y+V+ P G + G ++T+ +++L + TEYQI+V A+ Sbjct: 370 MVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTV-LKNLMSLTEYQIAVFAIYAH 428 Query: 411 TSSEPISIMEKTQPMKVQVE------CSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLE 464 T+SE + E T + + + + +K D V G Y I A + A E Sbjct: 429 TASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASG-YLILYAPLTEGLAGDE 487 Query: 465 VLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMT 524 K +I I L P+TE+T+ + F TG+ T Sbjct: 488 ---KEMKIGETHTDIELSGLL--PNTEYTVTVYA----------MFGEEASDPVTGQETT 532 Query: 525 YVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSD-VEIFAVGVKDAVRSE 583 + P SNV +T +S I N+D EI V V Sbjct: 533 LA---LSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPITTFP 589 Query: 584 LEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD-LSFSE 642 L+ + +P E + +D Q + L + VP + L E Sbjct: 590 LKGL-TPLTEYTIAIFSIYDEGQ--------------SEPLTGVFTTEEVPAQQYLEIDE 634 Query: 643 VTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVT 702 VT+ F+ W P + + + + G VV S V+ L+P T Y V++ Sbjct: 635 VTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLL 694 Query: 703 AEYEDGFSIPLA--------------------GEETTEEVKGAPRNLKVTDETTDSFKIT 742 A +DG + T + RNL V DETT S ++ Sbjct: 695 AVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVK 754 Query: 743 WTQAPGRVLRYRIIYRPVAGGESRE----VTTPPNQRRRTLENLIPDTKYEVSVIPEYFS 798 W + V ++R+ Y G E V P +Q L+ L+PDT+Y+V+V P Y Sbjct: 755 WDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTD 814 Query: 799 GPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA-GGETQ 857 G G ++ T G P++LRVS+ + ++++W VK Y + Y PV+ G T Sbjct: 815 GEGVSVSAPGKTLPSSG-PQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTL 873 Query: 858 EVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917 E V D ++ L G Y + + A ASG DAL G TL +L K + Sbjct: 874 ETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFL--GVTNLQAKHVE 931 Query: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977 TS+ A+W YRV +SL D E + LQP+++Y+ISV+ Sbjct: 932 MTSLCAHW-QVHRHATAYRVVIESL-QDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYT 989 Query: 978 TYSSGEG 984 EG Sbjct: 990 KLQEIEG 996 Score = 417 bits (1073), Expect = e-116 Identities = 298/909 (32%), Positives = 445/909 (48%), Gaps = 64/909 (7%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 +V G+ V PP+ L +S ++++W GYK+++TP T+G + + L++ Sbjct: 25 IVQGQ--VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTP-TSGGKTNQLNLQNTA 81 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEP------ISIMEKTQPMKVQVEC--------- 431 T ++ L D Y + + A S+P I +EK + K +V+ Sbjct: 82 TKAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRP 141 Query: 432 SRGVDIK--------ADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQ 483 S ++K ADIV LVDGS+SIG NF VR FLE LV +F++ + +I L Q Sbjct: 142 SSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQ 201 Query: 484 YSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK 543 YS DP E+ L F+ +++IEA+ PY+GG+T TG A+ Y+ E F P GSR+ V K Sbjct: 202 YSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSK 261 Query: 544 VMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFD 603 + ILITDGKS D P+ LR S VE+FA+GVK+A +EL+ IAS P THV+ V +FD Sbjct: 262 IGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFD 321 Query: 604 AFQRISFELTQSICLRIEQELAAIKKKAYV---PPKDLSFSEVTSYGFKTNWSPAGENVF 660 + LT+++C R+E++ IK A+ PP +L SEVT+ F NW+ A NV Sbjct: 322 LMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVE 381 Query: 661 SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE 720 Y + Y G VV + +S VL +L T Y + V A Y S L G ETT Sbjct: 382 KYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTL 441 Query: 721 EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVA---GGESREVTTPPNQRRR 777 + A +L + D T +S ++ W PG Y I+Y P+ G+ +E+ Sbjct: 442 ALPMA-SDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPLTEGLAGDEKEMKIGETHTDI 499 Query: 778 TLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGA 837 L L+P+T+Y V+V + P+TG T + PR+LR+S+ +++ +L+W Sbjct: 500 ELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLAL-SPPRNLRISNVGSNSARLTWDPT 558 Query: 838 PGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFG 897 ++ Y + Y G E EV V TT L+GL T+Y +++ ++Y G + L G Sbjct: 559 SRQINGYRIVYNNADGTEINEVEVDPITT-FPLKGLTPLTEYTIAIFSIYDEGQSEPLTG 617 Query: 898 EGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDA 957 TT EE + Q L ++T S W +++ W +Y T E L E+ Sbjct: 618 VFTT-EEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGG-KTEEVVLKEEQ 675 Query: 958 IHTMIENLQPETKYRISVFATYSSG-EGEPLTG-----------DATTELSQDSKT---- 1001 +IE L+P T+Y +S+ A G E E +T ATT + S T Sbjct: 676 DSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQ 735 Query: 1002 -----LKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMV---AKVPPTVTSTVL 1052 L V +ET +++RV W + V +RV Y G ++ V VP + + +L Sbjct: 736 TGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLL 795 Query: 1053 KRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG 1112 K L P T Y +TV PIY GEG G T P+NL+ S+ + R+TW+P Sbjct: 796 KPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITWDPPSS 854 Query: 1113 EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQ 1172 VKGY++ + P E VG NT+++ L +G Y V +F G S L G Sbjct: 855 PVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGM 914 Query: 1173 EMTTLSDTT 1181 T T Sbjct: 915 VKTLFLGVT 923 Score = 338 bits (867), Expect = 5e-92 Identities = 227/772 (29%), Positives = 375/772 (48%), Gaps = 37/772 (4%) Query: 637 DLSFSEVTSYGFKTNWS--PAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPE 694 DL +VT + W P + E DE + + T + LS L P Sbjct: 448 DLLLYDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPN 507 Query: 695 TLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYR 754 T Y V V A + + S P+ G+ETT + PRNL++++ ++S ++TW ++ YR Sbjct: 508 TEYTVTVYAMFGEEASDPVTGQETTLALS-PPRNLRISNVGSNSARLTWDPTSRQINGYR 566 Query: 755 IIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814 I+Y G E EV P L+ L P T+Y +++ Y G PLTG TEEV Sbjct: 567 IVYNNADGTEINEVEVDPITTF-PLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVP 625 Query: 815 GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLK 874 + L + + TT + +++W + + + PV GG+T+EV ++ + + V++GL+ Sbjct: 626 AQ-QYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLE 684 Query: 875 EGTQYALSVTALYASGA-GDALFGEGTTLEE-------------------RGSPQDLVTK 914 GT+Y +S+ A+ G+ + + GTTL+ + ++LV Sbjct: 685 PGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVG 744 Query: 915 DITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDT---GEKNLPEDAIHTMIENLQPETKY 971 D T +S+ W + V+ +RV++ + D + G +P + +++ L P+T+Y Sbjct: 745 DETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804 Query: 972 RISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031 +++V Y+ GEG ++ T S + L+V EE N +R+TW P V YR+VY+ Sbjct: 805 KVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYK 864 Query: 1032 PHG-RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSP 1090 P G + V + + ++ L Y++ + G G T F Sbjct: 865 PVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTL--FLGV 922 Query: 1091 RNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAG 1150 NL+ M+S W+ Y+V DR+ E VG L+ Sbjct: 923 TNLQAKHVEMTSLCAHWQ-VHRHATAYRVVIESL-QDRQKQESTVGGGTTRHCFYGLQPD 980 Query: 1151 TTYKVNVFGMFDGGESSPLVGQEMTTLSDT---TVMPILSSGMECLTRAEADIVLLVDGS 1207 + YK++V+ E + E T T T P + E A+AD+V +VDGS Sbjct: 981 SEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGS 1040 Query: 1208 WSIGRANFRTVRSFISRIVEVFD-IGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAV 1266 WSIG NF + SF+ V + IG Q+A+ Q++ DPRTE++LNA++ K++LL A+ Sbjct: 1041 WSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAI 1100 Query: 1267 ANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDE 1326 ++ YKGGNT TG A+ ++R F ++G R K+ V+ITDG+SQDDV S++++ + Sbjct: 1101 KHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDDVNKISREMQLD 1160 Query: 1327 GVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNS 1378 G +FAIG+ +AD EL I + P H + V DF++ +I D+L +C + Sbjct: 1161 GYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELITFVCET 1212 Score = 195 bits (495), Expect = 7e-49 Identities = 108/265 (40%), Positives = 156/265 (58%), Gaps = 4/265 (1%) Query: 55 YRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTI-TSYDEVEESVPVIGQLTIQ 113 YR+ ++ D +E T+ TT L P++EY +++ T E+E P + + Sbjct: 948 YRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEG--PSVSIMEKT 1005 Query: 114 TGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFD-I 172 T+P P ++ +A DLVF+VDGSWS+G NF I+ F+ + V A + I Sbjct: 1006 QSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKI 1065 Query: 173 GEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFT 232 G + T+V +VQ++ D RTEF LN Y ++ LL AIK I YKGGNT TG AI Y+ FT Sbjct: 1066 GTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFT 1125 Query: 233 ESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPS 292 +G R G PKV ++ITDG+SQD+V +RE++ G +F++G+ AD EL I S PS Sbjct: 1126 AESGTRRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPS 1185 Query: 293 LNHVFNVANFDAIVDIQNEIISQVC 317 HVF V +FDA I++E+I+ VC Sbjct: 1186 ARHVFFVDDFDAFKKIEDELITFVC 1210 Score = 181 bits (458), Expect = 1e-44 Identities = 128/402 (31%), Positives = 201/402 (50%), Gaps = 28/402 (6%) Query: 299 VANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSP 358 + N + +D +I + SG + L +V + + +NL A V + +W Sbjct: 886 ITNLLSGMDYNVKIFASQASGFSDALTGMV--KTLFLGVTNLQAKHVEMTSLCAHWQVHR 943 Query: 359 SPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISI 418 T Y+V++ + +Q + +VG TT L D+EY+ISV +SI Sbjct: 944 H-ATAYRVVIESLQDRQKQES-TVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSI 1001 Query: 419 MEKTQPMKVQ-------VECSRGV--DIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKS 469 MEKTQ + + + ++ V KAD+VF+VDGS+SIG NF K+ +FL V + Sbjct: 1002 MEKTQSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGA 1061 Query: 470 F-EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVRE 528 +I + Q+++VQ++ DP TEF L + E +++AI Y+GG+T TGKA+ YVR+ Sbjct: 1062 LNKIGTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRD 1121 Query: 529 KIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIA 588 +F G+R +PKV+++ITDG+S D + +++ IFA+GV DA SEL +I Sbjct: 1122 TLFTAESGTRRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIG 1181 Query: 589 SPPAETHVFTVEDFDAFQRISFELTQSICLRIEQ----------ELAAIKKKAYVPPKDL 638 S P+ HVF V+DFDAF++I EL +C +LA K + Sbjct: 1182 SKPSARHVFFVDDFDAFKKIEDELITFVCETASATCPVVHKDGIDLAGFKMMEMFGLVEK 1241 Query: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEP 680 FS V + P NVF + +K+A + P Sbjct: 1242 DFSSVEG----VSMEPGTFNVFPCYQLHKDALVSQPTRYLHP 1279 Score = 156 bits (394), Expect = 3e-37 Identities = 95/309 (30%), Positives = 154/309 (49%), Gaps = 15/309 (4%) Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFT 2260 T L NV + QI W +P Y+L ++P G + ++ ++ + T Sbjct: 34 TRLRYNVISHDSIQISWK------APRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQ 87 Query: 2261 GLSPDTDYGVTVFVQTPNLEGPGVS-------VKEHTTVKPTEAPTEPPTPPPPPTIPPA 2313 GL PD +Y V + + E +++ KP + P + Sbjct: 88 GLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEV 147 Query: 2314 RDVCKG-AKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEV 2372 + VC+ A ADIV L D SWSIG NF V F+ N V FD + ++ QYS + Sbjct: 148 KFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFD-VGSEKTRIGLAQYSGDP 206 Query: 2373 KSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVV 2432 + E+ LN ++ K + A++N+ Y+GGNT TG AL +I E E+G R V K+ +++ Sbjct: 207 RIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILI 266 Query: 2433 TDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKI 2492 TDG+SQD++ + +++SG +F +GV + D NEL IAS+P HV+ V +F+ + Sbjct: 267 TDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTV 326 Query: 2493 EDNLITFVC 2501 ++L +C Sbjct: 327 VESLTRTLC 335 Score = 54.7 bits (130), Expect = 1e-06 Identities = 31/64 (48%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Query: 2742 TQDSVGPPGPPGPAGG--PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799 TQ GPPGP GP+G PG+ GP G G GPPG G GP GP G PG P+ Sbjct: 1708 TQGPRGPPGPAGPSGESRPGSPGPPGS---PGPRGPPGHLGVPGPQGPSGQPGYCDPSSC 1764 Query: 2800 SIPG 2803 S G Sbjct: 1765 SAYG 1768 Score = 53.1 bits (126), Expect = 4e-06 Identities = 24/86 (27%), Positives = 43/86 (50%) Query: 1383 GDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLK 1442 G + P+ L + +H S ++SW P YK+ P SGGK + + T +++ Sbjct: 28 GQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQ 87 Query: 1443 DLKPETEYVVNVYSVVEDEYSEPLKG 1468 L P+ Y V + + +D+ S+P +G Sbjct: 88 GLMPDQNYTVQIIAYNKDKESKPAQG 113 Score = 37.7 bits (86), Expect = 0.18 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%) Query: 2019 QGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRN 2078 QG+ P P LR + +S+ ++W G Y+++ +PT G ++ + Sbjct: 27 QGQVAP---PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTAT 82 Query: 2079 NVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGR 2112 I+Q L PD Y + +IA +D + G R Sbjct: 83 KAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFR 116 Score = 37.4 bits (85), Expect = 0.23 Identities = 21/95 (22%), Positives = 40/95 (42%), Gaps = 1/95 (1%) Query: 1750 QAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVV 1809 Q + P L+ + +S+ + W G+ Y++ P++G G + + Sbjct: 27 QGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAI 85 Query: 1810 LQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844 +Q L PD YT+ + + D E G+ + K L Sbjct: 86 IQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDL 120 Score = 35.8 bits (81), Expect = 0.67 Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Query: 1948 NSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVAL 2007 +S+ + W G Y+++ +P G + ++ + T+ + ++ L+PD Y+V ++A Sbjct: 44 DSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAI-IQGLMPDQNYTVQIIAY 102 Query: 2008 YSDGEGNPSPAQGR 2021 D E P+ Q R Sbjct: 103 NKDKESKPAQGQFR 116 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 439 bits (1129), Expect = e-122 Identities = 277/771 (35%), Positives = 385/771 (49%), Gaps = 67/771 (8%) Query: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376 CK D+VFL D S S+G ++F KV +++ N V F E+ P +V V+YSD + F Sbjct: 32 CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTF-EVGPDRTRVGVVRYSDRPTTAF 90 Query: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 2433 +L + + A + + Y GGNT TG AL +I + + +G R + +V +++T Sbjct: 91 ELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLT 150 Query: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 2493 DGRSQD V AA ++G +F VGV + EL IAS+P HVF V DF + +KI Sbjct: 151 DGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIR 210 Query: 2494 DNLITFVCETATSSCPLIYLDG----YTSPGFKMLEAYNLTEKNFASVQGV--SLESGSF 2547 L +CE CP + ++G +T+ G K + ++L + SV+ + E+G+ Sbjct: 211 GKLRRRLCENVL--CPSVRVEGDRFKHTNGGTKEITGFDLMD--LFSVKEILGKRENGAQ 266 Query: 2548 PSYSAYRIQKNAF-VNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKP 2606 SY ++ +F V Q T D+ P GLP Y + FR + + + IWQ+ D+ P Sbjct: 267 SSY----VRMGSFPVVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIP 322 Query: 2607 QVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDC 2666 QV + D +K + + + V F V LF +HK+ + + +++V ++IDC Sbjct: 323 QVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDC 382 Query: 2667 YEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSR 2726 + I+E NI G ++GK L + F +Q I C + CCDIPS Sbjct: 383 ALVQTLPIEERENIDIQGKTVIGKRLY-DSVPIDFDLQRIVIYCDSRHAELETCCDIPS- 440 Query: 2727 RDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAK--------------GPRGERGISGA 2772 G C PP PP PG++ G +GE G++G Sbjct: 441 ---GPCQV------TVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGP 491 Query: 2773 IGPPGPRGDIGPPGPQGPPGPQGPNG-LSI-PGEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830 +G PGP+GDIG GP G PGP+G G + I P QG +G KG G PG PGR G+ G+ G Sbjct: 492 MGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRG 551 Query: 2831 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGK---------------PG 2875 PG +G PG G G G GP G PGPPG G+PG+ G G+ PG Sbjct: 552 EPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPG 611 Query: 2876 KPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPN 2932 KPGD GRPGPSG+ G +G++GD+ V ++ + G+ +Q Sbjct: 612 KPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671 Query: 2933 DYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT- 2991 +R GP G GPPG G RG+ G G PG PG G+QGPPG G+PG G G+ Sbjct: 672 GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731 Query: 2992 GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G G G PG PGP G TGPPG G GPPGPPG G G RG G PG Sbjct: 732 GLPGEIGFPGKPGPPGP--TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780 Score = 264 bits (675), Expect = 9e-70 Identities = 154/345 (44%), Positives = 181/345 (52%), Gaps = 47/345 (13%) Query: 2747 GPPGPPGPAGGPGAKGPRGERG---ISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IP 2802 GPPG G G GA GPRGE G + G G PG GD GP GPQGP GP+GP G + P Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332 Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPG---PPGPMGPPGDRGFTGKDGA---------- 2849 G G G G G+ G G G+PGLPG P GP G PG++G GK+G Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392 Query: 2850 --------MGPRGPPGPPGSPGSPGVTG---------PSGKPGKPGDHGRPGPSGLKGEK 2892 G +GPPG G PG PG+ G P G PG+ G G PGP G G Sbjct: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 1452 Query: 2893 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-QSSRNQPGPPGPPGP-- 2949 G RG+ S +R R + E+L R +L Q+P Y +SS+ +PGPPGPPG Sbjct: 1453 GLRGESPSMETLR---RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509 Query: 2950 -PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTG---SSGPRGLPGPPGP 3005 PG AG GEPG G+ G G G GP GERG G+ G G G GP G+PG PG Sbjct: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569 Query: 3006 QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 3050 G ++ G PG G +G GP G PG + GPPGPPG CD SQCA Sbjct: 1570 PGYAKDGLPGIPGPQGETGPAGHPG---LPGPPGPPGQCDPSQCA 1611 Score = 247 bits (630), Expect = 1e-64 Identities = 142/314 (45%), Positives = 164/314 (52%), Gaps = 67/314 (21%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIPGEQ 2805 G PG PG G PG GP G GI+GA GPPG +G PG +GPPGPQGP+GL IPGE+ Sbjct: 1186 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGLPGIPGEE 1242 Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------PGPP 2859 G++G G G PG PG+ G PGLPGP G GPPG +G TG GA GPRG PG Sbjct: 1243 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 1302 Query: 2860 GSPGSPGVTGPS------------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 G PG G TGP+ GK G PG G PGPSG G+KG +G+ S + Sbjct: 1303 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---- 1358 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967 PG GP GPPG G +G PG G PG Sbjct: 1359 ---------------------------------PGFLGPRGPPGEPGEKGVPGKEGVPGK 1385 Query: 2968 PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGP 3022 PG PG + GERG PG KG++G G G G PG PG +G + G PG G GP Sbjct: 1386 PGEPGFK---GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 1442 Query: 3023 PGPPGRPGNSGIRG 3036 PGPPG+PG G+RG Sbjct: 1443 PGPPGQPGFPGLRG 1456 Score = 238 bits (608), Expect = 5e-62 Identities = 143/330 (43%), Positives = 165/330 (50%), Gaps = 35/330 (10%) Query: 2748 PPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQG 2806 PPGPPG G PG KG +G G G G G +G+ GPPG GPPG GP G G G Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGP------MGPPGDRGFTGKDGAMGPRGPPGPPG 2860 G KGD G PG+PG G PG PGPPG GPPG +G GK+G GP+GP G PG Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237 Query: 2861 SPGSPGVTGPSGKPGKPGD---HGRP---------GPSGLKGEKGDRGDIASQNMMRAVA 2908 PG G G GKPG PG+ G P GP G KG GD G + A+ Sbjct: 1238 IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 1297 Query: 2909 RQVCEQL-----ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGG 2963 E L +G + P S PG PGP G PG G++GE G G Sbjct: 1298 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357 Query: 2964 RPGF------PGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE-SRTG 3012 PGF PG PG +G PG+ G+PG+ GE G G G +G GPPG +G+ G Sbjct: 1358 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG 1417 Query: 3013 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 PG G G GP G PG +G GPPGPPG Sbjct: 1418 IPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447 Score = 235 bits (600), Expect = 4e-61 Identities = 143/341 (41%), Positives = 167/341 (48%), Gaps = 45/341 (13%) Query: 2740 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAI----------GPPGPRGDIGPPGPQG 2789 T Q GP G GP G G GP G G+ G++ G PGPRG G PGP G Sbjct: 616 TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675 Query: 2790 PPGPQGPNGLS-IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG 2848 GP GP G PG QG +G KGD G PG+PG G G PGPPG GPPG G G G Sbjct: 676 ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPG 735 Query: 2849 AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP---GPSGLKGEKGDRGDIASQNMMR 2905 +G G PGPPG G PG GP+G PG PG G P G GL G+ G RG+I Q + Sbjct: 736 EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG 795 Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 2965 + E + G F + + + + + G G PG G G +GE GP G P Sbjct: 796 RPGEK-GEAGLPGAPG-FPGVRGE-----KGDQGEKGELGLPGLKGDRGEKGEAGPAGPP 848 Query: 2966 GFPGT----------PGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE--- 3008 G PGT PG QGP GE+G PG GE G G GP+G GPPG +G+ Sbjct: 849 GLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGA 908 Query: 3009 -------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G PG G+ GP GPPG G G+RG PG G Sbjct: 909 HGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 949 Score = 229 bits (585), Expect = 2e-59 Identities = 144/365 (39%), Positives = 160/365 (43%), Gaps = 77/365 (21%) Query: 2733 PAFPNSCTCTQD-SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPP 2791 P P S D +G GPPGP+G PG KG G RG+ G GP GP G G PG G Sbjct: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER 1089 Query: 2792 GPQGPNGLSI----------------------PGEQGRQGMKGDAGEPGLPGRTGT---- 2825 GP G GLS PG G G KGD G PG PGR GT Sbjct: 1090 GPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKK 1149 Query: 2826 -----PGLPGPPGPMGPPGDRGFTGKDGA---------------MGPRGPPGPPGSPGSP 2865 PGLPGPPG GP G +G G DG MGP G PGPPG+ G Sbjct: 1150 GEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 1209 Query: 2866 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925 G GP G G PG G PGP G G G I G+ + + Sbjct: 1210 GAAGPPGIQGSPGKEGPPGPQGPSGLPG----------------------IPGEEGKEGR 1247 Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 2985 P +PG PGP G G G +G G G PG G G G PG+ GLPG+ Sbjct: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307 Query: 2986 KGERG-TGSSGPRGLPGPPGPQGE-------SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037 G+ G TG GP+G GPPG G +G PG GS+G G PG PG G RGP Sbjct: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGP 1367 Query: 3038 PGPPG 3042 PG PG Sbjct: 1368 PGEPG 1372 Score = 228 bits (580), Expect = 9e-59 Identities = 156/398 (39%), Positives = 183/398 (45%), Gaps = 101/398 (25%) Query: 2747 GPPGPPGPAGG----------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 2796 GP GPPG G PG +GP+GE+G G G PG +G G GPQGP GP G Sbjct: 843 GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 902 Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR--- 2853 G ++G G G AG PG PG G PG GPPG +G PG RG GKDG G + Sbjct: 903 KG-----QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957 Query: 2854 ------GPPGPPGSPGSPGVTGP--SGKPGKPGDHGRPGPSGLKGEKGDRGDI-ASQNMM 2904 GP GP G PG+PG+ GP GK G+PG G PG G G K G + S+N Sbjct: 958 GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC- 1016 Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQP-----GPPGPPGPP---GSAGAR 2956 + GQ + ++ IP SR P GPPGP GPP GS G+R Sbjct: 1017 ----------ALGGQCVKGDRGAPGIPGS-PGSRGDPGIGVAGPPGPSGPPGDKGSPGSR 1065 Query: 2957 GEP------GPGGRPGFPGTPGMQGPP--------------------------------- 2977 G P GP GR G PG PG +GPP Sbjct: 1066 GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLP 1125 Query: 2978 ------GERGLPGEKGERGT----GSSGPRGLPGPP---GPQG-ESRTGPPGSTGSRGPP 3023 G++G+PG+ G GT G +GP GLPGPP GPQG + G G G +G Sbjct: 1126 GLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ 1185 Query: 3024 GPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG PG G G PGPPG D A+ P QG PG Sbjct: 1186 GHPGVPGFMGPPGNPGPPG-ADGIAGAAGPPGIQGSPG 1222 Score = 221 bits (564), Expect = 7e-57 Identities = 151/385 (39%), Positives = 171/385 (44%), Gaps = 112/385 (29%) Query: 2747 GPPGPPGPAGGPGAKGP------RGERGISG---AIGPPGPRGDIGPPGPQGPP--GPQG 2795 GP GPPG G PG +G RGE+G +G + GP GPRGD G PG GPP G G Sbjct: 928 GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 987 Query: 2796 PNGL----SIPGEQGR-----------------QGMKGDAGEPGLPGRTGTPGLP----- 2829 GL +PG G Q +KGD G PG+PG G+ G P Sbjct: 988 EPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVA 1047 Query: 2830 GPPGPMGPPGDRGFTGK---DGAMGPRGPPGPPGSPGSPGVTGPSGKPG-----KPGD-- 2879 GPPGP GPPGD+G G G GP+GP G G+PG+PG GP GKPG PGD Sbjct: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDIN 1107 Query: 2880 -----------HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLN 2928 G PG GL G KGD+G + G+ R Sbjct: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKG-------------------VPGKPGR------ 1142 Query: 2929 QIPNDYQSSRNQPGPPGPPGPPGSA---------GARGEPGPGGRPGFPGTPGMQGPPGE 2979 + + + GPPG PGPPG A GA GE G G G PG PG GPPG Sbjct: 1143 ---EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 1199 Query: 2980 RGLPGEKGERGT----------------GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGP 3022 G PG G G G GP GLPG PG +G E R G PG G G Sbjct: 1200 PGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK 1259 Query: 3023 PGPPGRPGNSGIRGPPGPPGYCDSS 3047 G PG PG G RGPPG G+ S Sbjct: 1260 AGEPGLPGPEGARGPPGFKGHTGDS 1284 Score = 214 bits (545), Expect = 1e-54 Identities = 155/428 (36%), Positives = 173/428 (40%), Gaps = 115/428 (26%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SI 2801 Q G GP GP G PGAKG G G GA G PG G +G PGP GPPG G GL Sbjct: 885 QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGT 944 Query: 2802 PGEQGRQGMKGDAGEPGLPGRTG------TPGLPGPPGPM--GPPGDRGFTGKDGAMGP- 2852 PG+ G +G KG AGE G PG G PGLPGPPG G PG RG G G +G Sbjct: 945 PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 1004 Query: 2853 ----------------------RGPPGPPGSPGSPG-----VTGPSGKPGKPGDHGRPGP 2885 RG PG PGSPGS G V GP G G PGD G PG Sbjct: 1005 AACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGS 1064 Query: 2886 SGLKGEKGDRG-----------------------DIASQNMMRAVARQVCEQLISGQMNR 2922 GL G G +G + S + +A+ VC G Sbjct: 1065 RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPG- 1123 Query: 2923 FNQMLNQIPN--------------DYQSSRNQPGPPGPPGPPGSAG---------ARGEP 2959 L +P + + + GPPG PGPPG AG A GE Sbjct: 1124 ----LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEV 1179 Query: 2960 GPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----------------GSSGPRGLPGPP 3003 G G G PG PG GPPG G PG G G G GP GLPG P Sbjct: 1180 GQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIP 1239 Query: 3004 GPQG----ESRTGPPGSTGSRGPPG------PPGRPGNSGIRGPPGPPGYCDSSQCASIP 3053 G +G + + GPPG G G PG G PG G G G PG S +P Sbjct: 1240 GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLP 1299 Query: 3054 YNGQGYPG 3061 +G PG Sbjct: 1300 -GQEGLPG 1306 Score = 211 bits (538), Expect = 7e-54 Identities = 148/415 (35%), Positives = 167/415 (40%), Gaps = 134/415 (32%) Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPP---------------GPAGGPGAKGPRGER 2767 +P G P P +G PG P GP G PG KG GER Sbjct: 721 VPGPPGPGGSPGLPGE-------IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER 773 Query: 2768 GISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-------SIPGEQGRQGMKGD------- 2813 G G G PG RG+IG G G PG +G GL + GE+G QG KG+ Sbjct: 774 GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833 Query: 2814 -----------AGEPGLPGRT-------------------GTPGLP------------GP 2831 AG PGLPG T G PGLP GP Sbjct: 834 GDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893 Query: 2832 PGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891 GP GPPG +G G GA G G PG PG G+PG +GP G G PG G PG G +GE Sbjct: 894 QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953 Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951 KG G+ S + R PG PG PGPPG Sbjct: 954 KGAAGEEGSPGPV-------------------------------GPRGDPGAPGLPGPPG 982 Query: 2952 SAGARGEPGPGGRPGFPG-----------------------TPGMQGPPGERGLPGEKGE 2988 G GEPG G PG PG G +G PG G PG +G+ Sbjct: 983 K-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGD 1041 Query: 2989 RGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G G +GP G GPPG +G G PG G +GP G G PGN G RGPPG PG Sbjct: 1042 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096 Score = 147 bits (370), Expect = 2e-34 Identities = 75/184 (40%), Positives = 120/184 (65%), Gaps = 3/184 (1%) Query: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQ 199 DLVFL+D S SVG+ +F+ + ++A LV F++G ++TRVGVV+YS T F L + Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 200 RDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARV---GFPKVAIIITDGKSQDE 256 ++E+ AA +++ Y GGNT TGDA+ Y+ +F+ AG R + +VAI++TDG+SQD Sbjct: 98 QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157 Query: 257 VEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQV 316 V A G+ +F++G+ A +EL++IAS P HVF+V++F+AI I+ ++ ++ Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217 Query: 317 CSGV 320 C V Sbjct: 218 CENV 221 Score = 140 bits (353), Expect = 2e-32 Identities = 75/181 (41%), Positives = 107/181 (59%), Gaps = 3/181 (1%) Query: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTK 499 D+VFL+D S S+G +F KVR ++ LV +FE+ P+R ++ +V+YS P T F L F Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 500 VEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN---VPKVMILITDGKSSDA 556 E++ A Y GG+TNTG A+ Y+ + F P G R +V IL+TDG+S D Sbjct: 98 QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157 Query: 557 FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616 D A + + IFAVGV +A++ ELE IAS P HVF V DF+A +I +L + + Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217 Query: 617 C 617 C Sbjct: 218 C 218 Score = 133 bits (334), Expect = 3e-30 Identities = 67/187 (35%), Positives = 112/187 (59%), Gaps = 3/187 (1%) Query: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258 D+V L+D S S+G+ +F VR +++ +V+ F++GP R ++ + +YS P T ++L Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97 Query: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRAR---KIGVLITDGKSQDD 1315 ++ + A L Y GGNT TG AL +I ++F AG RPR R ++ +L+TDG+SQD Sbjct: 98 QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157 Query: 1316 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 1375 V + G+ +FA+G+ A + EL+ IA++P H ++V+DF ++ +I L L Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217 Query: 1376 CNSVKGP 1382 C +V P Sbjct: 218 CENVLCP 224 Score = 108 bits (269), Expect = 1e-22 Identities = 59/128 (46%), Positives = 67/128 (52%), Gaps = 13/128 (10%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 PA+ S +Q GPPGPPG G PG GP GE G G G GP G IGP G +G G Sbjct: 1489 PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 1545 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 G G+ + GE G G+ G GEPG + G PG+PGP G GP G G Sbjct: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGPAGHPGLP-------- 1596 Query: 2853 RGPPGPPG 2860 GPPGPPG Sbjct: 1597 -GPPGPPG 1603 >gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] Length = 1284 Score = 427 bits (1098), Expect = e-119 Identities = 249/665 (37%), Positives = 369/665 (55%), Gaps = 22/665 (3%) Query: 1192 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEW 1251 CL AD+V LVDGSWSIG ++F+ V+ F++ ++ F+IGP +VQ+ L QYSGD +TEW Sbjct: 172 CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEW 231 Query: 1252 QLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGK 1311 LN+ K+ +L AV L YKGGNT TG+AL + QN + AG+RP A K+ +L+TDGK Sbjct: 232 DLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGK 291 Query: 1312 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDL 1371 SQDDV ++ LKD GV +FA+G+KNADE EL+++A+ P D ++V DF L + L Sbjct: 292 SQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLL 351 Query: 1372 TINLCNSVKGPG------------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY 1419 + +C ++G L AP++LV+S+ T S R+SWTP +Y + + Sbjct: 352 SRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVW 411 Query: 1420 YPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVV- 1478 GG +E V ST L +L TEY+V+V+ + E E L+G T P+P Sbjct: 412 RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471 Query: 1479 SLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 1538 +L + V P T+H+ WQP GAT Y++ P +EV++G ++ L L P Sbjct: 472 ALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRP--EVLLDGLEPG 529 Query: 1539 TEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIV 1598 +Y V+VQ++ SE +R T L P+ L DV+H VFWE P VR V Sbjct: 530 RDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589 Query: 1599 RYKTPEEDVK-EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 1657 Y + E + E + TS +L L S T YTV V+ ++ G S +T + TT+ P+ Sbjct: 590 TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPS 649 Query: 1658 PTNLKITEVTSEGFRGTWDHGA-SDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNP 1716 P+ L +TE+ + + W A S V +Y+ITW P G E + G+ T V L Sbjct: 650 PSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGR 709 Query: 1717 NTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA 1776 +T Y+V+I A Y D + SD + S R P +++P P NL + + T +SL V W P Sbjct: 710 HTEYDVTILAYYRDGARSDPV--SLRYTPSTVSRSP---PSNLALASETPDSLQVSWTPP 764 Query: 1777 SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMT 1836 GRV Y +TY P++G G E++ ++ G ++ V L L+ T Y + VS++Y G ++ Sbjct: 765 LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824 Query: 1837 GRGKT 1841 G+T Sbjct: 825 ATGQT 829 Score = 355 bits (910), Expect = 5e-97 Identities = 189/491 (38%), Positives = 275/491 (56%), Gaps = 46/491 (9%) Query: 2500 VCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNA 2559 V T ++CP + DG + PGF ++ A++L EK +AS++GV++E +F + + K+A Sbjct: 823 VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881 Query: 2560 FVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTL 2619 + + +D++P LPP +TI+ L RLLPETP + FA+WQ+T D++P +GV+ D K+L Sbjct: 882 QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941 Query: 2620 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGN 2679 ++F++D R +Q TFD +EV+ +F+GSFHKVH+ V V++Y+DC ++ E+ + E G+ Sbjct: 942 TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001 Query: 2680 ITTDGYEILGKLLKGE---RKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFP 2736 G+ LG+L K SAAFQ+Q IVCS W DRCC++P+ RD CPAF Sbjct: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061 Query: 2737 NSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 2796 ++C+C+ ++ GPPGP G PPG G G PG QG PGP+GP Sbjct: 1062 SACSCSSETPGPPGPQG---------------------PPGLPGRNGTPGEQGFPGPRGP 1100 Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856 G+KG+ G+ GLPG G PG G PG +G G +G G +G G GPP Sbjct: 1101 -----------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149 Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLI 2916 GP G G G G SG+ G P G GP+GL G KG+RG+ + + + V + Sbjct: 1150 GPRGFQGMAGARGTSGERGPP---GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASH 1206 Query: 2917 SGQMNRFNQMLNQIPNDYQSSRNQPG--PPGPPGPPGSAGARGEPGPGGR----PGFPGT 2970 + + F++ + P + +PG P G PG A GE G GGR G PG Sbjct: 1207 VSKFDSFHEN-TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGA 1265 Query: 2971 PGMQGPPGERG 2981 G G PG++G Sbjct: 1266 VGQMGSPGQQG 1276 Score = 302 bits (774), Expect = 3e-81 Identities = 224/695 (32%), Positives = 336/695 (48%), Gaps = 24/695 (3%) Query: 437 IKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKK 496 + AD+VFLVDGS+SIG ++F +V+ FL ++ FEI P++VQ+ L QYS D TE+ L Sbjct: 176 VPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNS 235 Query: 497 FTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDA 556 + E ++ A+ Y+GG+T TG A+T+V + P+ G R KV+IL+TDGKS D Sbjct: 236 LSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDD 295 Query: 557 FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616 A L++ V +FAVGVK+A +EL +ASPP + V +V DF ++ L++ I Sbjct: 296 VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355 Query: 617 CLRIE-----QELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAA 670 C R++ Q AA +P P L S+VTS + +W+PA + Y I ++ + Sbjct: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASR 415 Query: 671 GDD--EVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 G EV V PA+ST L +L T YLV+V YE G L G TT + PR Sbjct: 416 GGTPREVVVEGPAASTE--LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLP-PPRA 472 Query: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTK 787 L + T + +TW + G Y + P + GE E + L+ L P Sbjct: 473 LTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRD 531 Query: 788 YEVSVIPEYFSGP-GTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLV 846 YEVSV + GP G+ G A PR L SD + ++ W GAP V+ V Sbjct: 532 YEVSV--QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589 Query: 847 TYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERG 906 TY GG + + G+ T+ L L T Y + VT LY G L G TT ++ Sbjct: 590 TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT-KKAP 648 Query: 907 SPQDLVTKDITDTSIGAYW-TSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENL 965 SP L ++ ++ W +AP V Y+++W L + E ++P + ++ L Sbjct: 649 SPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGL 707 Query: 966 QPETKYRISVFATYSSG-EGEP--LTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGK 1022 T+Y +++ A Y G +P L +T L + ET ++++V+W P G+ Sbjct: 708 GRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGR 767 Query: 1023 VVNYRVVYRP-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSG 1081 V++Y + Y P G G + VP + L LQ T Y + V IY G + +G Sbjct: 768 VLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATG 827 Query: 1082 TTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKG 1116 TA P M +F + E A ++G Sbjct: 828 QTACPALRPDGSLPGFDLMVAFSLV-EKAYASIRG 861 Score = 199 bits (506), Expect = 3e-50 Identities = 125/457 (27%), Positives = 227/457 (49%), Gaps = 58/457 (12%) Query: 12 LGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFT 71 LGA L ++A L ++ E+ + M W + +GY + V P +E Sbjct: 17 LGATLGREQVQAS----GLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVI 72 Query: 72 LSASTTETLLSELVPETEYVVTITSY----------------DEVEESVPVIGQLTIQTG 115 L+ T + + L P Y + I D S+ Q + +G Sbjct: 73 LTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSSLDRSSQRPLGSG 132 Query: 116 SSTKPVEKKPGKTEIQ-----------------------KCSVSAWTDLVFLVDGSWSVG 152 + +P G + + +C D+VFLVDGSWS+G Sbjct: 133 AP-EPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADMVFLVDGSWSIG 191 Query: 153 RNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPY 212 ++F+ + DF+A++++ F+IG +K +VG+ QYS D +TE++LN ++++LAA++++ Y Sbjct: 192 HSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRY 251 Query: 213 KGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVF 272 KGGNT TG A+ +++ +AG R KV I++TDGKSQD+V AR L+++GV VF Sbjct: 252 KGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVF 311 Query: 273 SLGIKAADAKELKQIASTP---SLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVS 329 ++G+K AD EL+ +AS P +++ V + A+ + + +I Q G + G + Sbjct: 312 AVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAA 371 Query: 330 -GEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTT 388 + + P++L+ +V+S ++L+W P+P Y ++ G+ + + GP +T Sbjct: 372 PALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAAST 431 Query: 389 LSVRDLSADTEYQISV---------SAMKGMTSSEPI 416 + +L++ TEY +SV ++G+ ++ P+ Sbjct: 432 -ELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPL 467 Score = 178 bits (452), Expect = 6e-44 Identities = 142/467 (30%), Positives = 211/467 (45%), Gaps = 22/467 (4%) Query: 1655 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 1714 +PAPT+L +++VTS R +W Y I W E ++ G + NL Sbjct: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436 Query: 1715 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 1774 T Y VS+ IY G L L T AP PR L + T ++ + W Sbjct: 437 ASRTEYLVSVFPIYEG--------GVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ 488 Query: 1775 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLY-PDGEGG 1833 P++G Y + P++ +G E+ + + V+L L+P Y ++V SL P+G Sbjct: 489 PSAGATH-YLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEA 547 Query: 1834 RMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPG 1893 R R +T L R+L D S V W+ A R ++ Y + GG PG Sbjct: 548 RGI-RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG 606 Query: 1894 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQV-YNPTP-NSLD 1951 N A L L T+YTV V +Y GG ++ TGR + Q+ P +++ Sbjct: 607 NATSATLGPLSSSTTYTVRVTCLYP--GGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664 Query: 1952 VRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSD 2010 + W AP VL Y++ ++P+ G + I VPGN L L T Y V ++A Y D Sbjct: 665 LAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRD 723 Query: 2011 GEGNPSPAQGR----TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 2066 G P R T+ RS P NL + ET +SL V+W G V Y + Y+P G Sbjct: 724 G-ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLG 782 Query: 2067 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 2113 ++ +VPG R++V L LQ T Y++ V A+Y G ++ G+T Sbjct: 783 PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Score = 177 bits (448), Expect = 2e-43 Identities = 136/448 (30%), Positives = 205/448 (45%), Gaps = 12/448 (2%) Query: 725 APRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIP 784 AP +L ++ T+ S +++WT AP L+Y I++R GG REV L NL Sbjct: 379 APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNLAS 438 Query: 785 DTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQY 844 T+Y VSV P Y G G L G T + PR L ++ T T+ L+W + G Y Sbjct: 439 RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPP-PRALTLAAVTPRTVHLTWQPSAGAT-HY 496 Query: 845 LVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLE 903 LV +P + GE +E V+ +L GL+ G Y +SV +L +A G Sbjct: 497 LVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR-GIRARTP 555 Query: 904 ERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIE 963 P+ L D++ + +W AP VR RV++ S + +G+ P +A + Sbjct: 556 TLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSS-EGGHSGQTEAPGNATSATLG 614 Query: 964 NLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK 1022 L T Y + V Y G LTG TT+ + L + E + +++ W AP Sbjct: 615 PLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSG 674 Query: 1023 VVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK----LRQ 1078 V+ Y++ + P G GK VP + + VL L T YD+T+L Y+ G LR Sbjct: 675 VLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRY 734 Query: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPY 1138 + +T SR P NL + T S +V+W P G V Y +T+ P + V Sbjct: 735 -TPSTVSR-SPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGA 792 Query: 1139 DNTVVLEELRAGTTYKVNVFGMFDGGES 1166 + V L +L+A T Y+V V ++ G S Sbjct: 793 RSHVTLPDLQAATKYRVLVSAIYAAGRS 820 Score = 145 bits (367), Expect = 5e-34 Identities = 102/326 (31%), Positives = 147/326 (45%), Gaps = 35/326 (10%) Query: 2218 DTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF--- 2273 D +KW + Y +++ P G QE+ + GLSP Y + +F Sbjct: 40 DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99 Query: 2274 -------------------------VQTPNLEGPGVSVKEHTTVKPTEAPTEPP---TPP 2305 Q P G HT E +EP TP Sbjct: 100 GSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPS 159 Query: 2306 PPPTIP--PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQV 2363 P P P AD+VFL D SWSIG +F +V F+ + + F EI P +QV Sbjct: 160 QDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKVQV 218 Query: 2364 SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK 2423 QYS + ++E+ LN+ + K L A++ +RY+GGNT TG ALT + + L +G+R Sbjct: 219 GLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP 278 Query: 2424 NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV 2483 KV+++VTDG+SQD+V AA V++ G +VF VGV + D EL +AS P + V V Sbjct: 279 EAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSV 338 Query: 2484 DDFESFEKIEDNLITFVCETATSSCP 2509 DF + L +C+ P Sbjct: 339 LDFLQLGALAGLLSRLICQRLQGGSP 364 Score = 143 bits (360), Expect = 3e-33 Identities = 124/454 (27%), Positives = 193/454 (42%), Gaps = 11/454 (2%) Query: 1756 PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKP 1815 P +L + TS+S+ + W PA KY I ++ S G G + + G S L L Sbjct: 380 PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRG-GTPREVVVEGPAASTELHNLAS 438 Query: 1816 DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 1875 T Y ++V +Y G G + G T PL R L + + T+++ W + G Y Sbjct: 439 RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG-ATHYL 497 Query: 1876 LFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 1934 + +PA+ G EE + +L L+P Y V+V + RT Sbjct: 498 VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557 Query: 1935 GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 1994 R++ + + ++ V W+ AP PV RV Y +G ++ PGN L L Sbjct: 558 APPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQT-EAPGNATSATLGPL 616 Query: 1995 IPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAW-DHADGPVQ 2053 T Y+V + LY G + + T P L + +++ +AW A V Sbjct: 617 SSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVL 676 Query: 2054 QYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG---DGGHLTGN 2110 Y+I ++P +G+ +VPG +L L T Y +T++A Y DG D L Sbjct: 677 VYQITWTP-LGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYT 735 Query: 2111 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTS 2168 TV PP N+ ++ E +VSW P VL Y + Y P P + + G + Sbjct: 736 PSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSH 795 Query: 2169 YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 2202 TL +L +T Y V V A Y +G S ++ G T Sbjct: 796 VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829 Score = 113 bits (283), Expect = 3e-24 Identities = 94/332 (28%), Positives = 145/332 (43%), Gaps = 8/332 (2%) Query: 1946 TPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLV 2005 T +S+ + W PAP L+Y +V+ G P E +VV G L L T Y V++ Sbjct: 389 TSSSIRLSWTPAPRHPLKYLIVWRASRGGTPRE-VVVEGPAASTELHNLASRTEYLVSVF 447 Query: 2006 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 2065 +Y G G T P PR L + T ++ + W + G Y + SP Sbjct: 448 PIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATH-YLVRCSPASPK 506 Query: 2066 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG-NGRTVGLLPPQNIHI 2124 +E V R V+L L+P Y+++V ++ +G G RT L PP+++ Sbjct: 507 GEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGIRARTPTLAPPRHLGF 565 Query: 2125 SDEWYTRFRVSWDPSPSPVLGYKIVY-KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 2183 SD + RV W+ +P PV ++ Y G + G TS TL L+ STTY V Sbjct: 566 SDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVR 625 Query: 2184 VYAQYDSGLSVPLTDQGTTLYL-NVTDLKTYQIGWDTFCVKW--SPHRAATSYRLKLSPA 2240 V Y G S LT + TT + + L ++ D + W + Y++ +P Sbjct: 626 VTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL 685 Query: 2241 DGTRGQEITVRGSETSHCFTGLSPDTDYGVTV 2272 + EI+V G+ + GL T+Y VT+ Sbjct: 686 GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTI 717 Score = 106 bits (264), Expect = 4e-22 Identities = 59/125 (47%), Positives = 69/125 (55%), Gaps = 20/125 (16%) Query: 2937 SRNQPGPPGPPGPPG------SAGARGEPGPGGRPGFPGT------PGMQGPPGERGLPG 2984 S PGPPGP GPPG + G +G PGP G PG G PG+QG PG +G+PG Sbjct: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126 Query: 2985 EKGERGT----GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPP---GPPGRPGNSGIRG 3036 G +G G G GLPGPPGP+G + G G++G RGPP GP G PG G RG Sbjct: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186 Query: 3037 PPGPP 3041 G P Sbjct: 1187 EKGEP 1191 Score = 106 bits (264), Expect = 4e-22 Identities = 85/241 (35%), Positives = 89/241 (36%), Gaps = 63/241 (26%) Query: 2829 PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888 PGPPGP GPPG G G G G GP GPPG G G G G G PG G PG GL Sbjct: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130 Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948 +G KG RG G PGPPG Sbjct: 1131 QGPKGMRG----------------------------------------LEGTAGLPGPPG 1150 Query: 2949 P---PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT------------GS 2993 P G AGARG G G PG G G+ GP GERG GE T Sbjct: 1151 PRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210 Query: 2994 SGPRGLPGPPGPQGESR----TGPPGSTGSRGPPGPPGRPGNSGI----RGPPGPPGYCD 3045 PP P E + T P GS G+R PG G G RG PG G Sbjct: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270 Query: 3046 S 3046 S Sbjct: 1271 S 1271 Score = 103 bits (256), Expect = 3e-21 Identities = 80/275 (29%), Positives = 124/275 (45%), Gaps = 5/275 (1%) Query: 902 LEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTM 961 L+ +P LV +T +SI WT AP Y + W++ E + A T Sbjct: 374 LDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR-EVVVEGPAASTE 432 Query: 962 IENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPG 1021 + NL T+Y +SVF Y G GE L G TT + L + T T+ +TW+P+ G Sbjct: 433 LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG 492 Query: 1022 KVVNYRVVYRPHG-RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080 +Y V P +G++ +V +L L+P Y+++V + + EG +G Sbjct: 493 -ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGI 550 Query: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140 PR+L SD + + RV WE AP V+ +VT+ + + G+ Sbjct: 551 RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTY-VSSEGGHSGQTEAPGNAT 609 Query: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMT 1175 + L L + TTY V V ++ GG SS L G+ T Sbjct: 610 SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT 644 Score = 53.5 bits (127), Expect = 3e-06 Identities = 73/296 (24%), Positives = 109/296 (36%), Gaps = 17/296 (5%) Query: 2016 SPAQGR-------TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 2068 SP QG TLP P +L + T++S+ ++W A +Y I++ + G Sbjct: 363 SPRQGPAAAPALDTLP--APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420 Query: 2069 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 2128 E V G + L L T Y ++V +YE G G L G T L PP+ + ++ Sbjct: 421 E-VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479 Query: 2129 YTRFRVSWDPSPSPV--LGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYA 2186 ++W PS L P G E E VG L L P Y+V+V + Sbjct: 480 PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGR-PEVLLDGLEPGRDYEVSVQS 538 Query: 2187 -QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTR 2244 + G T L + D V W R R+ ++G Sbjct: 539 LRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGH 598 Query: 2245 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTE 2300 + G+ TS LS T Y V V P G ++ T K +P++ Sbjct: 599 SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG--GGSSTLTGRVTTKKAPSPSQ 652 Score = 47.4 bits (111), Expect = 2e-04 Identities = 28/62 (45%), Positives = 30/62 (48%), Gaps = 12/62 (19%) Query: 3000 PGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGY 3059 PGPPGPQG PPG PG G PG G GP GPPG +P QG+ Sbjct: 1071 PGPPGPQG-----PPGL------PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP-GLQGH 1118 Query: 3060 PG 3061 PG Sbjct: 1119 PG 1120 Score = 42.0 bits (97), Expect = 0.009 Identities = 24/87 (27%), Positives = 44/87 (50%) Query: 336 PPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLS 395 PPSNL + ++++W P V Y + P + + ++SV + +++ DL Sbjct: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802 Query: 396 ADTEYQISVSAMKGMTSSEPISIMEKT 422 A T+Y++ VSA+ SE +S +T Sbjct: 803 AATKYRVLVSAIYAAGRSEAVSATGQT 829 Score = 37.4 bits (85), Expect = 0.23 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 2/104 (1%) Query: 319 GVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQH 378 GV E L LV+ + PP L V+ + V L W PS T Y V +P + + Sbjct: 453 GVGEGLRGLVTTAPL-PPPRALTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEE 510 Query: 379 ALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 V + + L +Y++SV +++G SE I +T Sbjct: 511 EREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRART 554 Score = 37.4 bits (85), Expect = 0.23 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 3/111 (2%) Query: 13 GAALLLSSIEAEVDP-PSDLNFKIIDENTVHMSW-AKPVDPIVGYRITVDPTTDGPTKEF 70 G++ L + + P PS L+ + + V ++W A ++ Y+IT P +G E Sbjct: 634 GSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEI 693 Query: 71 TLSASTTETLLSELVPETEYVVTITS-YDEVEESVPVIGQLTIQTGSSTKP 120 ++ + +L L TEY VTI + Y + S PV + T T S + P Sbjct: 694 SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPP 744 Score = 37.0 bits (84), Expect = 0.30 Identities = 21/71 (29%), Positives = 31/71 (43%) Query: 820 LRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQY 879 LR++ +++ W + G YLV P+AG QEV + T + GL Y Sbjct: 32 LRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGY 91 Query: 880 ALSVTALYASG 890 L + L SG Sbjct: 92 TLQIFELTGSG 102 Score = 36.2 bits (82), Expect = 0.51 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 3/86 (3%) Query: 27 PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD-GPTKEFTLSASTTETLLSELV 85 PPS+L +++ +SW P+ ++ Y +T P + GP K ++ + + L +L Sbjct: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802 Query: 86 PETEYVVTITSYDEV--EESVPVIGQ 109 T+Y V +++ E+V GQ Sbjct: 803 AATKYRVLVSAIYAAGRSEAVSATGQ 828 Score = 34.3 bits (77), Expect = 1.9 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 737 DSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796 D ++ W ++ G L Y + +P+AG +EV + T+ L P Y + + Sbjct: 40 DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFE-- 97 Query: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGET 856 +G G L A E V DL+ S S+ + SGAP + + P E Sbjct: 98 LTGSGRFLL--ARREFV---IEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEP 152 Query: 857 Q 857 Q Sbjct: 153 Q 153 Score = 33.9 bits (76), Expect = 2.5 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 2/75 (2%) Query: 23 AEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLL 81 A + PP L + TVH++W +P Y + P + G +E + E LL Sbjct: 465 APLPPPRALTLAAVTPRTVHLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLL 523 Query: 82 SELVPETEYVVTITS 96 L P +Y V++ S Sbjct: 524 DGLEPGRDYEVSVQS 538 Score = 32.7 bits (73), Expect = 5.7 Identities = 29/127 (22%), Positives = 49/127 (38%), Gaps = 16/127 (12%) Query: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 1919 L ++W +EG+ Y + P AG E+ V + T A + L P YT+ + + Sbjct: 42 LQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGS 101 Query: 1920 G-----------DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVY 1968 G + ++S R+ R L PTP+ P P + +V + Sbjct: 102 GRFLLARREFVIEDLKSSSLDRSSQRPLGSGAP--EPTPSHTG---SPDPEQASEPQVAF 156 Query: 1969 SPVDGTR 1975 +P R Sbjct: 157 TPSQDPR 163 >gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] Length = 2421 Score = 387 bits (995), Expect = e-107 Identities = 380/1540 (24%), Positives = 643/1540 (41%), Gaps = 145/1540 (9%) Query: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876 + W+ P + +Y++ + P G +E T+ G + ++GLK G Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687 Query: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931 T++ + T+ + + GE T + + VT +IT +S W SA Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746 Query: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991 V G+RV ++ + + +LP A I +L P KY ++V+ GE + + Sbjct: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806 Query: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051 T VD+ + ++ V W + YR+VY P G +P T S Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866 Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106 L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T + Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166 W P V GY+V P G+ + + + L G TY VF + G ES Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225 PL Q+ T L T + ++ E D +LV W+ RA R + Sbjct: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035 Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270 +++GP + L P +E+ ++ K + LQ +++P Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093 Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330 Y T T + + + + G+RP EAP + D G Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136 Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390 + + P + Y + + R + + N V P L P+N Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179 Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446 L + VSW + + Y++ P +G G E V ++S +L P Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239 Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT--GYI 1504 EY V+VY+V +D+ S P+ T + L+ D+ +++ ++W P+ +T GY Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYR 1299 Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564 ++ + P E + +V +T L P +Y ++V +++ S P T+ + T Sbjct: 1300 ITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357 Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEVDRSETSTSL 1621 +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + S+ + L Sbjct: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416 Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681 +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F W + Sbjct: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRAT 1475 Query: 1682 VSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 ++ YRI P S + E + N++ NL P T Y VSI A+ E ES LIG Sbjct: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-ESPLLIGQ 1534 Query: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800 + T+ + PR+L+V AT SL + WD + V+ YRITY + G Q T Sbjct: 1535 QSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586 Query: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT--------VRNLRV 1852 + G +++ + LKP YTITV ++ GR +KP++ ++V Sbjct: 1587 VPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTEIDKPSQMQV 1641 Query: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTV 1911 D ++++V+W + Y++ P G GP + + + LQP Y Sbjct: 1642 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY-- 1699 Query: 1912 TVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGPVLQYRVVYS 1969 VV VY + G + +T + + R + + +S+ + W+ G V +YRV YS Sbjct: 1700 -VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1758 Query: 1970 -PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-PAQGRTLPRS 2026 P DG E P G L+ L P + Y+V++VAL+ D E P Q +P Sbjct: 1759 SPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP-- 1814 Query: 2027 GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPL 2085 P +L+ T SLS W + + YR+ +P P+ E P ++V++ L Sbjct: 1815 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS-SSVVVSGL 1873 Query: 2086 QPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144 T Y+++V A+ + G T+ + PP+ ++D T +SW + Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933 Query: 2145 GYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203 G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T Sbjct: 1934 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1993 Query: 2204 YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTG 2261 ++L+ ++ V W P RA T Y +K P R R T TG Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053 Query: 2262 LSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301 L P T+Y + V N + + + TV+ T T P Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2092 Score = 297 bits (760), Expect = 1e-79 Identities = 307/1324 (23%), Positives = 527/1324 (39%), Gaps = 86/1324 (6%) Query: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 EQ L + P P D + +V WS + Y I Y + + Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733 P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ + Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917 Query: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792 T I WT V YR+ PV GE + + L P Y V Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977 Query: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852 PLT T+ P +L+ + T ST+ + W+ ++ Y +T Sbjct: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035 Query: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970 ++T+T+I WT AP R+ +K GE + + D+ ++ L P + Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148 Query: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028 Y ++ E + P+ T LS + + V+W + + YR+ Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208 Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086 P +G + V +S L P Y+++V + E S T Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPE 1266 Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPA-PGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145 +L D T SS + W P + GY++T G+ + E V + Sbjct: 1267 VPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326 Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205 L G Y ++V + +GGES+P + T + T + + G + + A Sbjct: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP------ 1380 Query: 1206 GSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQA 1265 SI NF S + +V ++ A+ + P TE+ ++ S+ + Sbjct: 1381 -PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQ 1435 Query: 1266 VANLPYKGG-----NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320 + P +G ++ TG+ + I +F T + PRA G I Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPRE 1494 Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380 ++ + + E + ++A + + + ++S Sbjct: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS--------------- 1539 Query: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETST 1439 + P +L + T S +SW P+ +V Y++ Y G QEF V +++ Sbjct: 1540 -----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594 Query: 1440 VLKDLKPETEYVVNVYSVV----EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ 1495 + LKP +Y + VY+V S+P+ +T + + DV ++ V+W Sbjct: 1595 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1654 Query: 1496 PVGG-ATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTS 1554 P TGY ++ P PT+ K GP +M + L P EY V+V A S Sbjct: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712 Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EV 1612 +P+ VT + RP+ L DV ++ + WE G+V +Y V Y +PE+ + E+ Sbjct: 1713 QPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771 Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672 D E + L+ L + YTVSV A+HD+ ES P+ ++T +PAPT+LK T+VT Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLS 1830 Query: 1673 GTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDE 1731 W ++ YR+ P + M+ I L D +++V L T YEVS+ A+ Sbjct: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL---- 1886 Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791 D + S ++TT S PR +V +AT ++T+ W + + +++ P+ Sbjct: 1887 ---KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1943 Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLR 1851 G+ Q TI S + L+P T Y I + +L + + T ++ NLR Sbjct: 1944 GQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLR 2001 Query: 1852 VYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYT 1910 + ++L V W Y + Y P E+VP P A + L+P T YT Sbjct: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061 Query: 1911 VTVV 1914 + V+ Sbjct: 2062 IYVI 2065 Score = 201 bits (510), Expect = 1e-50 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%) Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 2106 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 2161 ++ T+ PQ +S D + + W P + S ++GY+I G P+ E Sbjct: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314 Query: 2162 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220 FV YT+ L P YD++V + G S P T T TDL+ IG DT Sbjct: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374 Query: 2221 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 2272 V W+P + T++ ++ SP E+++ S+ + T L P T+Y V+V Sbjct: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429 Score = 201 bits (510), Expect = 1e-50 Identities = 157/551 (28%), Positives = 237/551 (43%), Gaps = 20/551 (3%) Query: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693 P+DL T +W V Y ITY E G+ V P S ++ +S LKP Sbjct: 1542 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1601 Query: 694 ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749 Y + V A G S P++ TE K P ++VTD +S + W + Sbjct: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1659 Query: 750 VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808 V YR+ P G G ++ T P+Q T+E L P +Y VSV + SG PL A Sbjct: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1719 Query: 809 ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYT-PVAGGETQEVTVRGDTTN 867 T R P+ L +D ++K++W G+V +Y VTY+ P G G+ Sbjct: 1720 VTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777 Query: 868 TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927 LQGL+ G++Y +SV AL+ L G +T +P DL +T TS+ A WT Sbjct: 1778 AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTP 1835 Query: 928 APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987 + GYRV E NL D+ ++ L TKY +SV+A + P Sbjct: 1836 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1895 Query: 988 TGDATT-ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046 G TT E + +V + TE T+ ++W+ + ++V P + + P Sbjct: 1896 QGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1955 Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106 V S + LQP T Y I + + +TA +P NL+ T +S V+ Sbjct: 1956 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA--IDAPSNLRFLATTPNSLLVS 2013 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNT--VVLEELRAGTTYKVNVFGMFDGG 1164 W+P + GY + + G R E+V P + L GT Y + V + + Sbjct: 2014 WQPPRARITGYIIKYEKPGSPPR--EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 2071 Query: 1165 ESSPLVGQEMT 1175 +S PL+G++ T Sbjct: 2072 KSEPLIGRKKT 2082 Score = 193 bits (490), Expect = 3e-48 Identities = 214/887 (24%), Positives = 369/887 (41%), Gaps = 87/887 (9%) Query: 334 VEPPSNL-IAMEVSSKYVKLNWNPSPSP-VTGYKVILTPMTAGSRQHALS--VGPQTTTL 389 + PP+NL + + + ++W S +P +TGY++ TP T G + ++L V ++ Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP-TNGQQGNSLEEVVHADQSSC 1232 Query: 390 SVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSY 449 + +LS EY +SV +K E + I + P Q+ VDI + L Sbjct: 1233 TFDNLSPGLEYNVSVYTVKD--DKESVPISDTIIPEVPQLTDLSFVDITDSSIGL--RWT 1288 Query: 450 SIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYS---RDPHTEFTLKKFTKVEDIIEA 506 + + + R + + I + V S+ Y+ +P ++ + T + Sbjct: 1289 PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN----- 1343 Query: 507 INTFPYRGGSTNTGKAMTYVREKIFVPSKGSR--SNVPKVMILITDGKSSDAFRDPAIKL 564 GG + A T + ++ VP +N+ + +T P+I L Sbjct: 1344 -------GGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP------PSIDL 1386 Query: 565 RNSDVEIFAVGVKDAVRSELEAIASPPAE--THVFTVEDFDAFQRISFELTQSICLRIEQ 622 N V V ++ V +EL S A T++ ++ +E +S LR Q Sbjct: 1387 TNFLVRYSPVKNEEDV-AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445 Query: 623 ELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEP 680 K P + FS++T+ F +W + Y I + + +G V P Sbjct: 1446 ------KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV-P 1498 Query: 681 ASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFK 740 S S+ L++L P T Y+V++ A S L G+++T V PR+L+V T S Sbjct: 1499 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--VSDVPRDLEVVAATPTSLL 1556 Query: 741 ITWTQAPGRVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799 I+W V YRI Y G +E T P ++ T+ L P Y ++V G Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616 Query: 800 PGT----PLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAG-G 854 P++ N TE + P ++V+D +++ + W + V Y VT TP G G Sbjct: 1617 DSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674 Query: 855 ETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTK 914 T+ T D T ++GL+ +Y +SV A SG L T +R P+ L Sbjct: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1732 Query: 915 DITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTM------------I 962 D+ SI W S G V YRV++ S PED IH + + Sbjct: 1733 DVDVDSIKIAWESPQGQVSRYRVTYSS------------PEDGIHELFPAPDGEEDTAEL 1780 Query: 963 ENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGK 1022 + L+P ++Y +SV A + E +PL G +T + + LK + T ++ W P + Sbjct: 1781 QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD-LKFTQVTPTSLSAQWTPPNVQ 1839 Query: 1023 VVNYRVVYRPHGR-GKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSG 1081 + YRV P + G + P +S V+ L T Y+++V + + QG Sbjct: 1840 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1899 Query: 1082 TTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNT 1141 TT PR + +D T ++ ++W + G++V P + + + P + Sbjct: 1900 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRS 1958 Query: 1142 VVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSS 1188 + L+ GT YK+ ++ + D SSP+V T + + + L++ Sbjct: 1959 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLAT 2005 Score = 176 bits (447), Expect = 2e-43 Identities = 214/960 (22%), Positives = 374/960 (38%), Gaps = 130/960 (13%) Query: 297 FNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP 356 + V + +D +I+ + G E ++ + V PP++L + +++ W P Sbjct: 1323 YTVTGLEPGIDYDISVITLINGG--ESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380 Query: 357 SPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP 415 PS +T + V +P+ LS+ P + + +L TEY +SVS++ S P Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440 Query: 416 ISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYSIGIANFVKVRAFLEVLVKSFEIS 473 + +KT G+D I F + S+++ +++ RA + + I Sbjct: 1441 LRGRQKT-----------GLDSPTGIDFSDITANSFTV---HWIAPRA----TITGYRIR 1482 Query: 474 PNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKI 530 + S + R PH+ TL T + + +I R S + Sbjct: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES------------PL 1530 Query: 531 FVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR-----------NSDVEIFAVGVK 577 + + + S+VP+ + ++ +S ++ PA+ +R NS V+ F V Sbjct: 1531 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV--- 1587 Query: 578 DAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD 637 +S P + TV + S ++ I + E+ P Sbjct: 1588 PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSKPISINYRTEID--------KPSQ 1638 Query: 638 LSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEPASSTSVVLSSLKPET 695 + ++V W P+ V Y +T K G + P T + + L+P Sbjct: 1639 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTV 1697 Query: 696 LYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRI 755 Y+V+V A+ G S PL T + P+ L TD DS KI W G+V RYR+ Sbjct: 1698 EYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRV 1755 Query: 756 IYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814 Y G P + L+ L P ++Y VSV+ + PL G +T Sbjct: 1756 TYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--AI 1813 Query: 815 GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP-VAGGETQEVTVRGDTTNTVLQGL 873 P DL+ + T +++ W+ ++ Y V TP G +E+ + D+++ V+ GL Sbjct: 1814 PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGL 1873 Query: 874 KEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVR 933 T+Y +SV AL + G TTLE P+ D T+T+I W + + Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933 Query: 934 GYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993 G++V ++ + D I LQP T Y+I ++ + P+ DA+T Sbjct: 1934 GFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992 Query: 994 ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPTVTSTVL 1052 + S L+ T N++ V+W+P ++ Y + Y +P +++V + P VT + Sbjct: 1993 AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051 Query: 1053 KRLQPQTTYDITVL--------------------------PIYKMGEG-KLRQGSGTTAS 1085 L+P T Y I V+ P Y G G +L SG S Sbjct: 2052 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2111 Query: 1086 -----RFKSPRNLKTSDPT--------------------MSSFRVTWEPAPGEVKGYKVT 1120 F+ +T+ PT +S ++W P + Y ++ Sbjct: 2112 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIIS 2170 Query: 1121 FHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDT 1180 HP G D + V + L L G TY + V + D + V +E+ T+ ++ Sbjct: 2171 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--QQRHKVREEVVTVGNS 2228 Score = 161 bits (407), Expect = 1e-38 Identities = 149/568 (26%), Positives = 249/568 (43%), Gaps = 27/568 (4%) Query: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697 S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y Sbjct: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786 Query: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756 +VNV EDG S+ L+ +TT AP + V S + W++ + YRI+ Sbjct: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844 Query: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810 Y P G S E+ P TL +L P +Y +++ + TP+ TG + Sbjct: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868 + V +PRDL+ + T + + W+ V Y V PV G Q + + +T Sbjct: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963 Query: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928 V GL G Y V A+ L + TT + +P +L + TD+++ WT Sbjct: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020 Query: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988 + GYR++ L + N+ + NLQP ++Y +S+ A + E T Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079 Query: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048 G TT S E TE T+ +TW PAP + +++ RP +G + +V Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136 Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107 S V+ L P Y T+ + + G+ + + P NL ++P V+W Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195 Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165 E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255 Query: 1166 SSPL---VGQEMTTLSDTTVMPILSSGM 1190 S P+ + E+ L+D + + I S + Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSI 1283 Score = 160 bits (405), Expect = 2e-38 Identities = 151/584 (25%), Positives = 255/584 (43%), Gaps = 28/584 (4%) Query: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669 E +S + I+QE + VP P+DL F EVT W+P V Y + Sbjct: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944 Query: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 E P S +T ++ L P Y V A S PL ++TT+ AP N Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002 Query: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788 L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062 Query: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848 VS++ + TG T + G+ ++ T +T+ ++W+ AP + + Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119 Query: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907 P GGE +EVT D+ + V+ GL G +Y ++ L DA + Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176 Query: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960 P +L + DT + ++ S + GYR++ + + N E+ +H Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232 Query: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPA- 1019 +NL P +Y +SV+ E P++ E+ Q + VD T++++ + W P Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD-ITDSSIGLRWTPLN 1291 Query: 1020 PGKVVNYRVVYRPHGRGKQMVAK-VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQ 1078 ++ YR+ G G + V +V + L+P YDI+V+ + GE Sbjct: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351 Query: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGP 1137 + TA P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P Sbjct: 1352 LTQQTA--VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409 Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 DN VVL L GT Y V+V +++ ES+PL G++ T L T Sbjct: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1453 Score = 159 bits (403), Expect = 3e-38 Identities = 201/869 (23%), Positives = 340/869 (39%), Gaps = 73/869 (8%) Query: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390 + V P +L +EV+ V + W P S VTGY+V + P+ G L + + T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963 Query: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450 V LS Y V A+ S+P++ + T+ +D ++ F V+ + S Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 + + RA +I+ R+ + L T + + ++ +++ + Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570 P R N A Y + + KG++ + PK + T + + ++ + + Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104 Query: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625 I +G K VR A + ++ + + T + ++ A Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164 Query: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678 I K P P +L G T +W ++ Y IT G + + V Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 A +S +L P Y V+V +D S+P++ +T +L D T S Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSS 1282 Query: 739 FKITWTQA-PGRVLRYRIIYRPVAGGES---REVTTPPNQRRRTLENLIPDTKYEVSVIP 794 + WT ++ YRI VA GE E + T+ L P Y++SVI Sbjct: 1283 IGLRWTPLNSSTIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1340 Query: 795 EYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPG-KVKQYLVTYTPVAG 853 G P T + P DLR ++ TM+++W+ P + +LV Y+PV Sbjct: 1341 LINGGESAPTT--LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398 Query: 854 GE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 E E+++ VL L GT+Y +SV+++Y L G T SP + Sbjct: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGID 1456 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR 972 DIT S +W + + GYR+ + E +P + NL P T+Y Sbjct: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516 Query: 973 ISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRP 1032 +S+ A E L G +T +S + L+V T ++ ++W V YR+ Y Sbjct: 1517 VSIVALNGREESPLLIGQQST-VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575 Query: 1033 HGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGE--GKLRQGSGTTASRFK 1088 G G V + VP + ++ + L+P Y ITV + G+ + S + Sbjct: 1576 TG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634 Query: 1089 SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELR 1148 P ++ +D +S V W P+ V GY+VT P GP + +E L+ Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694 Query: 1149 AGTTYKVNVFGMFDGGESSPLVGQEMTTL 1177 Y V+V+ GES PLV +T + Sbjct: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI 1723 Score = 105 bits (263), Expect = 5e-22 Identities = 119/490 (24%), Positives = 188/490 (38%), Gaps = 49/490 (10%) Query: 622 QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679 Q L + A P DL F++VT W+P + Y +T KE G + + Sbjct: 1803 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1862 Query: 680 PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739 P SS SVV+S L T Y V+V A + S P G TT E PR +VTD T + Sbjct: 1863 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1921 Query: 740 KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799 I+W + +++ P G + T P+ R T+ L P T Y++ + + Sbjct: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981 Query: 800 PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859 +P+ +A+T P +LR T +++ +SW ++ Y++ Y G +EV Sbjct: 1982 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 2038 Query: 860 T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917 R T + GL+ GT+Y + V AL + + L G T+++ VT Sbjct: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQK----TPFVTHPGY 2094 Query: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977 DT G G G++ + E+ H P T A Sbjct: 2095 DTGNGIQLPGTSG-------------QQPSVGQQMIFEE--HGFRRTTPPTT-------A 2132 Query: 978 TYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGK 1037 T P + V +E + ++W P Y + P G + Sbjct: 2133 TPIRHRPRPYPPN-------------VGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDE 2178 Query: 1038 Q-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTS 1096 + + +VP T TS L L TY+I V + K+R+ T + N T Sbjct: 2179 EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTD 2238 Query: 1097 DPTMSSFRVT 1106 D + V+ Sbjct: 2239 DSCFDPYTVS 2248 Score = 66.6 bits (161), Expect = 4e-10 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Query: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73 +L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859 Query: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133 + LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916 Query: 134 SVS 136 V+ Sbjct: 917 EVT 919 Score = 65.9 bits (159), Expect = 6e-10 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%) Query: 2011 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 2064 GE + P Q T P S GP + VF T NS + W+ + +Y + + P Sbjct: 595 GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650 Query: 2065 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 2106 + T+PG N+ ++ L+P Y+ +I++ + G Sbjct: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710 Query: 2107 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 2164 +TG L + +++ + F VSW + V G+++ Y+ G Sbjct: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770 Query: 2165 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 2223 TS + +L P Y VNVY + G S+ L+ TT D Q+ + V+ Sbjct: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830 Query: 2224 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 2282 WS P T YR+ SP+ E+ + + S + L P Y +T++ N E Sbjct: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890 Query: 2283 GVSVKEHTTVKPTEAPTEPP 2302 V +++ TT P P Sbjct: 891 PVVIQQETTGTPRSDTVPSP 910 Score = 59.7 bits (143), Expect = 4e-08 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82 E+D PS + + +N++ + W P+ GYR+T P GPTK T TE + Sbjct: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691 Query: 83 ELVPETEYVVTITSYDEVEESVPVI 107 L P EYVV++ + + ES P++ Sbjct: 1692 GLQPTVEYVVSVYAQNPSGESQPLV 1716 Score = 58.9 bits (141), Expect = 7e-08 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 ++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L Sbjct: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 L P +EY V++ + +ES G T+Q GSS P + +T I V WT Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108 Score = 53.9 bits (128), Expect = 2e-06 Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 2/90 (2%) Query: 22 EAEVDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTET 79 + V PP+DL F I +T+ ++WA P + + + P + E ++S S Sbjct: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414 Query: 80 LLSELVPETEYVVTITSYDEVEESVPVIGQ 109 +L+ L+P TEYVV+++S E ES P+ G+ Sbjct: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444 Score = 50.1 bits (118), Expect = 3e-05 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 +D P+ ++F I N+ + W P I GYRI P G +E + S L+ Sbjct: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEYVV+I + + EES +IGQ Sbjct: 1509 LTPGTEYVVSIVALNGREESPLLIGQ 1534 Score = 50.1 bits (118), Expect = 3e-05 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76 L+ + +D P L F +D +++ ++W P + YR+T DG + F Sbjct: 1715 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1774 Query: 77 TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135 +T L L P +EY V++ + + ES P+IG T S+ P T++ S+ Sbjct: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1829 Query: 136 SA-WT 139 SA WT Sbjct: 1830 SAQWT 1834 Score = 48.9 bits (115), Expect = 8e-05 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75 L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+ Sbjct: 1805 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864 Query: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111 ++ ++S L+ T+Y V++ + + S P G +T Sbjct: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900 Score = 45.1 bits (105), Expect = 0.001 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372 + Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849 Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 GS L++ ++++ DL +Y I++ A++ S P+ I ++T Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898 Score = 45.1 bits (105), Expect = 0.001 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70 A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106 + A + L P EY V++ + + +ESVP+ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259 Score = 44.3 bits (103), Expect = 0.002 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%) Query: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 LL+ D P DL ++ +SW P + YRIT T + P +EFT+ Sbjct: 1530 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589 Query: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130 S + +S L P +Y +T+ + TG P KP +TEI Sbjct: 1590 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1633 Query: 131 QKCSVSAWTDL 141 K S TD+ Sbjct: 1634 DKPSQMQVTDV 1644 Score = 43.1 bits (100), Expect = 0.004 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 9/102 (8%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83 +D PS+L F N++ +SW P I GY I + P + TE ++ Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP 125 L P TEY + + + ++S P+IG+ K V+K P Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPLIGR--------KKTVQKTP 2087 Score = 36.2 bits (82), Expect = 0.51 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64 L L + A +++++E V PP E T+ +SW + I G+++ P Sbjct: 1886 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1944 Query: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107 + T+ ++ L P T+Y + + + ++ S PV+ Sbjct: 1945 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987 Score = 35.0 bits (79), Expect = 1.1 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 V P DL F + + V + W P + GYR+ V P G + + T ++ Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118 L P Y + + ES P+ Q T + + T Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001 Score = 33.5 bits (75), Expect = 3.3 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101 +SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797 Query: 102 ESVPVIGQLTIQTGSSTKP 120 E L + T +T P Sbjct: 798 EQ-----SLILSTSQTTAP 811 >gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] Length = 2477 Score = 386 bits (991), Expect = e-106 Identities = 377/1533 (24%), Positives = 640/1533 (41%), Gaps = 144/1533 (9%) Query: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876 + W+ P + +Y++ + P G +E T+ G + ++GLK G Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687 Query: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931 T++ + T+ + + GE T + + VT +IT +S W SA Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746 Query: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991 V G+RV ++ + + +LP A I +L P KY ++V+ GE + + Sbjct: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806 Query: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051 T VD+ + ++ V W + YR+VY P G +P T S Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866 Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106 L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T + Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166 W P V GY+V P G+ + + + L G TY VF + G ES Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225 PL Q+ T L T + ++ E D +LV W+ RA R + Sbjct: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035 Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270 +++GP + L P +E+ ++ K + LQ +++P Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093 Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330 Y T T + + + + G+RP EAP + D G Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136 Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390 + + P + Y + + R + + N V P L P+N Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179 Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446 L + VSW + + Y++ P +G G E V ++S +L P Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239 Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT--GYI 1504 EY V+VY+V +D+ S P+ T + L+ D+ +++ ++W P+ +T GY Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYR 1299 Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564 ++ + P E + +V +T L P +Y ++V +++ S P T+ + T Sbjct: 1300 ITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357 Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEVDRSETSTSL 1621 +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + S+ + L Sbjct: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416 Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681 +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F W + Sbjct: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRAT 1475 Query: 1682 VSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 ++ YRI P S + E + N++ NL P T Y VSI A+ E ES LIG Sbjct: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-ESPLLIGQ 1534 Query: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800 + T+ + PR+L+V AT SL + WD + V+ YRITY + G Q T Sbjct: 1535 QSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586 Query: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT--------VRNLRV 1852 + G +++ + LKP YTITV ++ GR +KP++ ++V Sbjct: 1587 VPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTEIDKPSQMQV 1641 Query: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTV 1911 D ++++V+W + Y++ P G GP + + + LQP Y Sbjct: 1642 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY-- 1699 Query: 1912 TVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGPVLQYRVVYS 1969 VV VY + G + +T + + R + + +S+ + W+ G V +YRV YS Sbjct: 1700 -VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1758 Query: 1970 -PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-PAQGRTLPRS 2026 P DG E P G L+ L P + Y+V++VAL+ D E P Q +P Sbjct: 1759 SPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP-- 1814 Query: 2027 GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPL 2085 P +L+ T SLS W + + YR+ +P P+ E P ++V++ L Sbjct: 1815 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS-SSVVVSGL 1873 Query: 2086 QPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144 T Y+++V A+ + G T+ + PP+ ++D T +SW + Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933 Query: 2145 GYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203 G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T Sbjct: 1934 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1993 Query: 2204 YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTG 2261 ++L+ ++ V W P RA T Y +K P R R T TG Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053 Query: 2262 LSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294 L P T+Y + V N + + ++ T P Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086 Score = 297 bits (760), Expect = 1e-79 Identities = 307/1324 (23%), Positives = 527/1324 (39%), Gaps = 86/1324 (6%) Query: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 EQ L + P P D + +V WS + Y I Y + + Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733 P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ + Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917 Query: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792 T I WT V YR+ PV GE + + L P Y V Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977 Query: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852 PLT T+ P +L+ + T ST+ + W+ ++ Y +T Sbjct: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035 Query: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970 ++T+T+I WT AP R+ +K GE + + D+ ++ L P + Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148 Query: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028 Y ++ E + P+ T LS + + V+W + + YR+ Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208 Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086 P +G + V +S L P Y+++V + E S T Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPE 1266 Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPA-PGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145 +L D T SS + W P + GY++T G+ + E V + Sbjct: 1267 VPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326 Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205 L G Y ++V + +GGES+P + T + T + + G + + A Sbjct: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP------ 1380 Query: 1206 GSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQA 1265 SI NF S + +V ++ A+ + P TE+ ++ S+ + Sbjct: 1381 -PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQ 1435 Query: 1266 VANLPYKGG-----NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320 + P +G ++ TG+ + I +F T + PRA G I Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPRE 1494 Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380 ++ + + E + ++A + + + ++S Sbjct: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS--------------- 1539 Query: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETST 1439 + P +L + T S +SW P+ +V Y++ Y G QEF V +++ Sbjct: 1540 -----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594 Query: 1440 VLKDLKPETEYVVNVYSVV----EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ 1495 + LKP +Y + VY+V S+P+ +T + + DV ++ V+W Sbjct: 1595 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1654 Query: 1496 PVGG-ATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTS 1554 P TGY ++ P PT+ K GP +M + L P EY V+V A S Sbjct: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712 Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EV 1612 +P+ VT + RP+ L DV ++ + WE G+V +Y V Y +PE+ + E+ Sbjct: 1713 QPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771 Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672 D E + L+ L + YTVSV A+HD+ ES P+ ++T +PAPT+LK T+VT Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLS 1830 Query: 1673 GTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDE 1731 W ++ YR+ P + M+ I L D +++V L T YEVS+ A+ Sbjct: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL---- 1886 Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791 D + S ++TT S PR +V +AT ++T+ W + + +++ P+ Sbjct: 1887 ---KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1943 Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLR 1851 G+ Q TI S + L+P T Y I + +L + + T ++ NLR Sbjct: 1944 GQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLR 2001 Query: 1852 VYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYT 1910 + ++L V W Y + Y P E+VP P A + L+P T YT Sbjct: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061 Query: 1911 VTVV 1914 + V+ Sbjct: 2062 IYVI 2065 Score = 261 bits (667), Expect = 7e-69 Identities = 250/933 (26%), Positives = 398/933 (42%), Gaps = 51/933 (5%) Query: 1393 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 1451 ++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+ Sbjct: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787 Query: 1452 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 1509 VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P Sbjct: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847 Query: 1510 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 1568 + T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR Sbjct: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 1569 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 1620 P+DL+ +VT + + W P V Y ++ P E + + + R+ T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963 Query: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680 + L Y V AV ES P+TAQ+TT+ + APTNL+ T W + Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022 Query: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 ++ YR+T + + + NL P + Y VS+ AI ++ S Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075 Query: 1741 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 1798 + + TT P S P N +V T ++ + W PA R+ +++ +PS +G E Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128 Query: 1799 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 1857 + S+V+ L P Y T+ L E PL+ NL + +P T Sbjct: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188 Query: 1858 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 1914 L V W+ + + Y++ P G G + + + NL P Y V+V Sbjct: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248 Query: 1915 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPA-PGPVLQYRVVYSPVDG 1973 V + + SDT + L ++ + T +S+ +RW P ++ YR+ Sbjct: 1249 TVKDDKESVPISDTIIPEVPQLT-DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGE 1307 Query: 1974 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 2033 P V + + L P Y ++++ L + GE P+ +T P +LR Sbjct: 1308 GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-PPPTDLRF 1366 Query: 2034 FGETTNSLSVAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 2092 +++ V W + + + YSP + ++ N V+L L P T Y Sbjct: 1367 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426 Query: 2093 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 2152 ++V +VYE + L G +T GL P I SD F V W + + GY+I + P Sbjct: 1427 VSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1485 Query: 2153 VG-SNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL 2210 S P E V S TL NL P T Y V++ A S L Q +T+ DL Sbjct: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545 Query: 2211 KTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDY 2268 + + + W +P YR+ G QE TV GS+++ +GL P DY Sbjct: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605 Query: 2269 GVTVFVQTPNLEGPG----VSVKEHTTV-KPTE 2296 +TV+ T + P +S+ T + KP++ Sbjct: 1606 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638 Score = 225 bits (573), Expect = 6e-58 Identities = 250/1005 (24%), Positives = 410/1005 (40%), Gaps = 90/1005 (8%) Query: 628 KKKAYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTS 685 ++ A PP DL F+ + + W+P ++ ++ + Y +++V + + S + Sbjct: 1354 QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1413 Query: 686 VVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQ 745 VVL++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W Sbjct: 1414 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIA 1471 Query: 746 APGRVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL 804 + YRI + P G RE P ++ TL NL P T+Y VS++ L Sbjct: 1472 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1531 Query: 805 TGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRG 863 G +T V PRDL V T +++ +SW V+ Y +TY G QE TV G Sbjct: 1532 IGQQST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589 Query: 864 DTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDT 919 + + GLK G Y ++V A+ +G GD+ E P + D+ D Sbjct: 1590 SKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDN 1647 Query: 920 SIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATY 979 SI W + V GYRV+ T K D IE LQP +Y +SV+A Sbjct: 1648 SISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707 Query: 980 SSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQM 1039 SGE +PL A T + + K L + +++++ W+ G+V YRV Y G Sbjct: 1708 PSGESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1766 Query: 1040 VAKVPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDP 1098 + P T L+ L+P + Y ++V+ ++ E + G+ +TA +P +LK + Sbjct: 1767 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQV 1824 Query: 1099 TMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVF 1158 T +S W P ++ GY+V P + E+ + P ++VV+ L T Y+V+V+ Sbjct: 1825 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1884 Query: 1159 GMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205 + D S P G +T ++TT+ + E +T + D V + Sbjct: 1885 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PAN 1943 Query: 1206 GSWSIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQ 1264 G I R VRS+ I+ + D K L + + D S L+ Sbjct: 1944 GQTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDAPSNLR 2001 Query: 1265 AVANLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVE 1317 +A P +TG + + + + + RPR IT + + Sbjct: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061 Query: 1318 APSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT---IN 1374 LK+ IG K DE+ +++ + H + D S + +T + Sbjct: 2062 IYVIALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYD 2120 Query: 1375 LCNSVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEF 1430 N ++ PG + PS ++ E FR + P + + R++ YP + G +E Sbjct: 2121 TGNGIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYPPNVG--EEI 2175 Query: 1431 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 1490 + + V L P + S ++ S+ TT Sbjct: 2176 QIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQ-----------------------TT- 2211 Query: 1491 HVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV-- 1548 + W P + YI+S PV E P + R+ T LT L Y + V+A+ Sbjct: 2212 -ISWAPFQDTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 2268 Query: 1549 --LHDLTSEPVTV-REVTLPLPRPQDLKLRD---VTHSTMNVFWE 1587 H + E VTV V L +P D D V+H + WE Sbjct: 2269 QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2313 Score = 201 bits (510), Expect = 1e-50 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%) Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 2106 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 2161 ++ T+ PQ +S D + + W P + S ++GY+I G P+ E Sbjct: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314 Query: 2162 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220 FV YT+ L P YD++V + G S P T T TDL+ IG DT Sbjct: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374 Query: 2221 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 2272 V W+P + T++ ++ SP E+++ S+ + T L P T+Y V+V Sbjct: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429 Score = 173 bits (439), Expect = 2e-42 Identities = 183/796 (22%), Positives = 324/796 (40%), Gaps = 75/796 (9%) Query: 297 FNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP 356 + V + +D +I+ + G E ++ + V PP++L + +++ W P Sbjct: 1323 YTVTGLEPGIDYDISVITLINGG--ESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380 Query: 357 SPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP 415 PS +T + V +P+ LS+ P + + +L TEY +SVS++ S P Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440 Query: 416 ISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYSIGIANFVKVRAFLEVLVKSFEIS 473 + +KT G+D I F + S+++ +++ RA + + I Sbjct: 1441 LRGRQKT-----------GLDSPTGIDFSDITANSFTV---HWIAPRA----TITGYRIR 1482 Query: 474 PNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKI 530 + S + R PH+ TL T + + +I R S + Sbjct: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES------------PL 1530 Query: 531 FVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR-----------NSDVEIFAVGVK 577 + + + S+VP+ + ++ +S ++ PA+ +R NS V+ F V Sbjct: 1531 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV--- 1587 Query: 578 DAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD 637 +S P + TV + S ++ I + E+ P Sbjct: 1588 PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSKPISINYRTEID--------KPSQ 1638 Query: 638 LSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEPASSTSVVLSSLKPET 695 + ++V W P+ V Y +T K G + P T + + L+P Sbjct: 1639 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTV 1697 Query: 696 LYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRI 755 Y+V+V A+ G S PL T + P+ L TD DS KI W G+V RYR+ Sbjct: 1698 EYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRV 1755 Query: 756 IYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814 Y G P + L+ L P ++Y VSV+ + PL G +T Sbjct: 1756 TYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--AI 1813 Query: 815 GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP-VAGGETQEVTVRGDTTNTVLQGL 873 P DL+ + T +++ W+ ++ Y V TP G +E+ + D+++ V+ GL Sbjct: 1814 PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGL 1873 Query: 874 KEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVR 933 T+Y +SV AL + G TTLE P+ D T+T+I W + + Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933 Query: 934 GYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993 G++V ++ + D I LQP T Y+I ++ + P+ DA+T Sbjct: 1934 GFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992 Query: 994 ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPTVTSTVL 1052 + S L+ T N++ V+W+P ++ Y + Y +P +++V + P VT + Sbjct: 1993 AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051 Query: 1053 KRLQPQTTYDITVLPI 1068 L+P T Y I V+ + Sbjct: 2052 TGLEPGTEYTIYVIAL 2067 Score = 161 bits (407), Expect = 1e-38 Identities = 149/568 (26%), Positives = 249/568 (43%), Gaps = 27/568 (4%) Query: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697 S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y Sbjct: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786 Query: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756 +VNV EDG S+ L+ +TT AP + V S + W++ + YRI+ Sbjct: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844 Query: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810 Y P G S E+ P TL +L P +Y +++ + TP+ TG + Sbjct: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868 + V +PRDL+ + T + + W+ V Y V PV G Q + + +T Sbjct: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963 Query: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928 V GL G Y V A+ L + TT + +P +L + TD+++ WT Sbjct: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020 Query: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988 + GYR++ L + N+ + NLQP ++Y +S+ A + E T Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079 Query: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048 G TT S E TE T+ +TW PAP + +++ RP +G + +V Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136 Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107 S V+ L P Y T+ + + G+ + + P NL ++P V+W Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195 Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165 E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255 Query: 1166 SSPL---VGQEMTTLSDTTVMPILSSGM 1190 S P+ + E+ L+D + + I S + Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSI 1283 Score = 160 bits (405), Expect = 2e-38 Identities = 151/584 (25%), Positives = 255/584 (43%), Gaps = 28/584 (4%) Query: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669 E +S + I+QE + VP P+DL F EVT W+P V Y + Sbjct: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944 Query: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 E P S +T ++ L P Y V A S PL ++TT+ AP N Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002 Query: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788 L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062 Query: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848 VS++ + TG T + G+ ++ T +T+ ++W+ AP + + Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119 Query: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907 P GGE +EVT D+ + V+ GL G +Y ++ L DA + Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176 Query: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960 P +L + DT + ++ S + GYR++ + + N E+ +H Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232 Query: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPA- 1019 +NL P +Y +SV+ E P++ E+ Q + VD T++++ + W P Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD-ITDSSIGLRWTPLN 1291 Query: 1020 PGKVVNYRVVYRPHGRGKQMVAK-VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQ 1078 ++ YR+ G G + V +V + L+P YDI+V+ + GE Sbjct: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351 Query: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGP 1137 + TA P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P Sbjct: 1352 LTQQTA--VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409 Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 DN VVL L GT Y V+V +++ ES+PL G++ T L T Sbjct: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1453 Score = 159 bits (403), Expect = 3e-38 Identities = 201/869 (23%), Positives = 340/869 (39%), Gaps = 73/869 (8%) Query: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390 + V P +L +EV+ V + W P S VTGY+V + P+ G L + + T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963 Query: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450 V LS Y V A+ S+P++ + T+ +D ++ F V+ + S Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 + + RA +I+ R+ + L T + + ++ +++ + Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570 P R N A Y + + KG++ + PK + T + + ++ + + Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104 Query: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625 I +G K VR A + ++ + + T + ++ A Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164 Query: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678 I K P P +L G T +W ++ Y IT G + + V Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 A +S +L P Y V+V +D S+P++ +T +L D T S Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSS 1282 Query: 739 FKITWTQA-PGRVLRYRIIYRPVAGGES---REVTTPPNQRRRTLENLIPDTKYEVSVIP 794 + WT ++ YRI VA GE E + T+ L P Y++SVI Sbjct: 1283 IGLRWTPLNSSTIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1340 Query: 795 EYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPG-KVKQYLVTYTPVAG 853 G P T + P DLR ++ TM+++W+ P + +LV Y+PV Sbjct: 1341 LINGGESAPTT--LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398 Query: 854 GE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 E E+++ VL L GT+Y +SV+++Y L G T SP + Sbjct: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGID 1456 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR 972 DIT S +W + + GYR+ + E +P + NL P T+Y Sbjct: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516 Query: 973 ISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRP 1032 +S+ A E L G +T +S + L+V T ++ ++W V YR+ Y Sbjct: 1517 VSIVALNGREESPLLIGQQST-VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575 Query: 1033 HGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGE--GKLRQGSGTTASRFK 1088 G G V + VP + ++ + L+P Y ITV + G+ + S + Sbjct: 1576 TG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634 Query: 1089 SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELR 1148 P ++ +D +S V W P+ V GY+VT P GP + +E L+ Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694 Query: 1149 AGTTYKVNVFGMFDGGESSPLVGQEMTTL 1177 Y V+V+ GES PLV +T + Sbjct: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI 1723 Score = 104 bits (259), Expect = 2e-21 Identities = 135/566 (23%), Positives = 212/566 (37%), Gaps = 91/566 (16%) Query: 622 QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679 Q L + A P DL F++VT W+P + Y +T KE G + + Sbjct: 1803 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1862 Query: 680 PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739 P SS SVV+S L T Y V+V A + S P G TT E PR +VTD T + Sbjct: 1863 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1921 Query: 740 KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799 I+W + +++ P G + T P+ R T+ L P T Y++ + + Sbjct: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981 Query: 800 PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859 +P+ +A+T P +LR T +++ +SW ++ Y++ Y G +EV Sbjct: 1982 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 2038 Query: 860 T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917 R T + GL+ GT+Y + V AL + + L G T E PQ LVT Sbjct: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE---LPQ-LVT---- 2090 Query: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977 LP +H E L + + + F Sbjct: 2091 -----------------------------------LPHPNLHGP-EILDVPSTVQKTPFV 2114 Query: 978 T---YSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHG 1034 T Y +G G L G + + S + + E+ R T P + +R RP+ Sbjct: 2115 THPGYDTGNGIQLPGTSGQQPSVGQQMI----FEEHGFRRTTPPTTATPIRHRP--RPY- 2167 Query: 1035 RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK 1094 PP V + P+ D + P G G N Sbjct: 2168 ---------PPNVGEEIQIGHIPREDVDYHLYP----------HGPGLNP-------NAS 2201 Query: 1095 TSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYK 1154 T +S ++W P + Y ++ HP G D + V + L L G TY Sbjct: 2202 TGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYN 2260 Query: 1155 VNVFGMFDGGESSPLVGQEMTTLSDT 1180 + V + D + V +E+ T+ ++ Sbjct: 2261 IIVEALKD--QQRHKVREEVVTVGNS 2284 Score = 85.9 bits (211), Expect = 6e-16 Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 61/497 (12%) Query: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393 ++ PS + +V + + W PS SPVTGY+V TP + GP T +++ Sbjct: 1633 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1692 Query: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGV---DIKADIVFLVDGSYS 450 L EY +SV A S+P+ Q ++ +G+ D+ D + + S Sbjct: 1693 LQPTVEYVVSVYAQNPSGESQPL-----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ 1747 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 ++ + + E + +P+ + + P +E+T+ +D + + Sbjct: 1748 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD----MESQ 1803 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK------VMILITDGKSSDAFRDPAIKL 564 P G + A T ++ P+ S P + +T + + ++ I L Sbjct: 1804 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE--INL 1861 Query: 565 RNSDVEIFAVGVKDAVRSEL------EAIASPPAETHVFTVEDFDAFQRISFELTQSICL 618 + G+ A + E+ + + S PA+ V T+E+ Sbjct: 1862 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS--------------- 1906 Query: 619 RIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 PP+ ++ T +W E + + + A G + Sbjct: 1907 ---------------PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1951 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 S ++ L+P T Y + + ++ S P+ + +T AP NL+ T +S Sbjct: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST--AIDAPSNLRFLATTPNS 2009 Query: 739 FKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQ--RRRTLENLIPDTKYEVSVIPEY 796 ++W R+ Y I Y G REV P T+ L P T+Y + VI Sbjct: 2010 LLVSWQPPRARITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK 2068 Query: 797 FSGPGTPLTGNAATEEV 813 + PL G T+E+ Sbjct: 2069 NNQKSEPLIGRKKTDEL 2085 Score = 76.3 bits (186), Expect = 4e-13 Identities = 87/374 (23%), Positives = 149/374 (39%), Gaps = 54/374 (14%) Query: 1384 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 1443 ++ P +++ T + +SW ++++ ++V+ P +G + + S + Sbjct: 1904 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963 Query: 1444 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 1502 L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG Sbjct: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 2023 Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 1561 YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+ Sbjct: 2024 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 2081 Query: 1562 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 1614 VTLP P ++ DV + + PG Y T ++ Sbjct: 2082 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2132 Query: 1615 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTN----LKITEVTSE 1669 + S + +F + + +PP TA RP P P N ++I + E Sbjct: 2133 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183 Query: 1670 -----------GFRGTWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFEN 1713 G G +S I+WAPF D E I++ DE L F Sbjct: 2184 DVDYHLYPHGPGLNPNASTGQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR- 2240 Query: 1714 LNPNTIYEVSITAI 1727 P T ++T + Sbjct: 2241 -VPGTSTSATLTGL 2253 Score = 66.6 bits (161), Expect = 4e-10 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Query: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73 +L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859 Query: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133 + LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916 Query: 134 SVS 136 V+ Sbjct: 917 EVT 919 Score = 65.9 bits (159), Expect = 6e-10 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%) Query: 2011 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 2064 GE + P Q T P S GP + VF T NS + W+ + +Y + + P Sbjct: 595 GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650 Query: 2065 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 2106 + T+PG N+ ++ L+P Y+ +I++ + G Sbjct: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710 Query: 2107 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 2164 +TG L + +++ + F VSW + V G+++ Y+ G Sbjct: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770 Query: 2165 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 2223 TS + +L P Y VNVY + G S+ L+ TT D Q+ + V+ Sbjct: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830 Query: 2224 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 2282 WS P T YR+ SP+ E+ + + S + L P Y +T++ N E Sbjct: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890 Query: 2283 GVSVKEHTTVKPTEAPTEPP 2302 V +++ TT P P Sbjct: 891 PVVIQQETTGTPRSDTVPSP 910 Score = 59.7 bits (143), Expect = 4e-08 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82 E+D PS + + +N++ + W P+ GYR+T P GPTK T TE + Sbjct: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691 Query: 83 ELVPETEYVVTITSYDEVEESVPVI 107 L P EYVV++ + + ES P++ Sbjct: 1692 GLQPTVEYVVSVYAQNPSGESQPLV 1716 Score = 58.9 bits (141), Expect = 7e-08 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 ++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L Sbjct: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 L P +EY V++ + +ES G T+Q GSS P + +T I V WT Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108 Score = 53.9 bits (128), Expect = 2e-06 Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 2/90 (2%) Query: 22 EAEVDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTET 79 + V PP+DL F I +T+ ++WA P + + + P + E ++S S Sbjct: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414 Query: 80 LLSELVPETEYVVTITSYDEVEESVPVIGQ 109 +L+ L+P TEYVV+++S E ES P+ G+ Sbjct: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444 Score = 50.1 bits (118), Expect = 3e-05 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 +D P+ ++F I N+ + W P I GYRI P G +E + S L+ Sbjct: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEYVV+I + + EES +IGQ Sbjct: 1509 LTPGTEYVVSIVALNGREESPLLIGQ 1534 Score = 50.1 bits (118), Expect = 3e-05 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76 L+ + +D P L F +D +++ ++W P + YR+T DG + F Sbjct: 1715 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1774 Query: 77 TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135 +T L L P +EY V++ + + ES P+IG T S+ P T++ S+ Sbjct: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1829 Query: 136 SA-WT 139 SA WT Sbjct: 1830 SAQWT 1834 Score = 48.9 bits (115), Expect = 8e-05 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75 L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+ Sbjct: 1805 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864 Query: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111 ++ ++S L+ T+Y V++ + + S P G +T Sbjct: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900 Score = 45.1 bits (105), Expect = 0.001 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372 + Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849 Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 GS L++ ++++ DL +Y I++ A++ S P+ I ++T Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898 Score = 45.1 bits (105), Expect = 0.001 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70 A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106 + A + L P EY V++ + + +ESVP+ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259 Score = 45.1 bits (105), Expect = 0.001 Identities = 25/99 (25%), Positives = 45/99 (45%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 ++ ++ PSNL + + + ++W P + +TGY + + R+ P Sbjct: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 2046 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425 T ++ L TEY I V A+K SEP+ +KT + Sbjct: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 2085 Score = 44.3 bits (103), Expect = 0.002 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%) Query: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 LL+ D P DL ++ +SW P + YRIT T + P +EFT+ Sbjct: 1530 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589 Query: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130 S + +S L P +Y +T+ + TG P KP +TEI Sbjct: 1590 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1633 Query: 131 QKCSVSAWTDL 141 K S TD+ Sbjct: 1634 DKPSQMQVTDV 1644 Score = 42.7 bits (99), Expect = 0.005 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83 +D PS+L F N++ +SW P I GY I + P + TE ++ Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEY + + + ++S P+IG+ Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPLIGR 2079 Score = 36.2 bits (82), Expect = 0.51 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64 L L + A +++++E V PP E T+ +SW + I G+++ P Sbjct: 1886 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1944 Query: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107 + T+ ++ L P T+Y + + + ++ S PV+ Sbjct: 1945 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987 Score = 35.0 bits (79), Expect = 1.1 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 V P DL F + + V + W P + GYR+ V P G + + T ++ Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118 L P Y + + ES P+ Q T + + T Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001 Score = 33.5 bits (75), Expect = 3.3 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101 +SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797 Query: 102 ESVPVIGQLTIQTGSSTKP 120 E L + T +T P Sbjct: 798 EQ-----SLILSTSQTTAP 811 >gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] Length = 2330 Score = 383 bits (984), Expect = e-105 Identities = 357/1428 (25%), Positives = 594/1428 (41%), Gaps = 119/1428 (8%) Query: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876 + W+ P + +Y++ + P G +E T+ G + ++GLK G Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687 Query: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931 T++ + T+ + + GE T + + VT +IT +S W SA Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746 Query: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991 V G+RV ++ + + +LP A I +L P KY ++V+ GE + + Sbjct: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806 Query: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051 T VD+ + ++ V W + YR+VY P G +P T S Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866 Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106 L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T + Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166 W P V GY+V P G+ + + + L G TY VF + G ES Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225 PL Q+ T L T + ++ E D +LV W+ RA R + Sbjct: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035 Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270 +++GP + L P +E+ ++ K + LQ +++P Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093 Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330 Y T T + + + + G+RP EAP + D G Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136 Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390 + + P + Y + + R + + N V P L P+N Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179 Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446 L + VSW + + Y++ P +G G E V ++S +L P Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239 Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504 EY V+VY+V +D+ S P+ T P L ++GP TM V W P T ++ Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299 Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564 + Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V S P+ R+ T Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356 Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621 L P + D+T ++ V W + Y +R+ PE +E V S S +L Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415 Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681 +L T Y VS+ A++ ESP + Q++T P +L++ T +WD A Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474 Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 V YRIT+ G +S E + G ++T L P Y +++ A+ + D S Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530 Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799 + + I T+ K P +QV + NS++VKW P+S V YR+T P G G +T Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588 Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859 T G Q + ++ L+P Y ++V + P GE + T ++ + L D + Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDS 1647 Query: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVVPVYT 1918 + + W+ +G +Y++ Y+ G EL P P G + A L+ L+P + YTV+VV ++ Sbjct: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707 Query: 1919 EGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSE 1978 + + T T + +++ TP SL +W P + YRV +P + T P + Sbjct: 1708 DMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766 Query: 1979 SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGET 2037 I + ++ V + L+ T Y V++ AL P+ TL S PR RV T Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826 Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097 +++++W + +++ P G + T P R+ I LQP T YKI + Sbjct: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI-TGLQPGTDYKIYLYT 1885 Query: 2098 VYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS-- 2155 + ++ + + T + P N+ VSW P + + GY I Y+ GS Sbjct: 1886 LNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1944 Query: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203 E + +T T+ L P T Y + V A ++ S PL + T+ Sbjct: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992 Score = 334 bits (856), Expect = 9e-91 Identities = 325/1304 (24%), Positives = 551/1304 (42%), Gaps = 84/1304 (6%) Query: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697 S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y Sbjct: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786 Query: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756 +VNV EDG S+ L+ +TT AP + V S + W++ + YRI+ Sbjct: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844 Query: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810 Y P G S E+ P TL +L P +Y +++ + TP+ TG + Sbjct: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868 + V +PRDL+ + T + + W+ V Y V PV G Q + + +T Sbjct: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963 Query: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928 V GL G Y V A+ L + TT + +P +L + TD+++ WT Sbjct: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020 Query: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988 + GYR++ L + N+ + NLQP ++Y +S+ A + E T Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079 Query: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048 G TT S E TE T+ +TW PAP + +++ RP +G + +V Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136 Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107 S V+ L P Y T+ + + G+ + + P NL ++P V+W Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195 Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165 E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255 Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225 S P+ + + T + + G + + A SI NF S + Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308 Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280 +V ++ A+ + P TE+ ++ S+ + + P +G ++ TG+ Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364 Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340 + I +F T + PRA G I ++ + + E Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423 Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400 + ++A + + + ++S + P +L + T S Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463 Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458 +SW P+ +V Y++ Y G QEF V +++ + LKP +Y + VY+V Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523 Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514 S+P+ +T + + DV ++ V+W P TGY ++ P Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583 Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574 PT+ K GP +M + L P EY V+V A S+P+ VT + RP+ L Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAF 1640 Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EVDRSETSTSLKDLFSQTLYTV 1632 DV ++ + WE G+V +Y V Y +PE+ + E+ D E + L+ L + YTV Sbjct: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTV 1700 Query: 1633 SVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPF 1692 SV A+HD+ ES P+ ++T +PAPT+LK T+VT W ++ YR+ P Sbjct: 1701 SVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759 Query: 1693 GSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQA 1751 + M+ I L D +++V L T YEVS+ A+ D + S ++TT Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL-------KDTLTSRPAQGVVTTLE 1812 Query: 1752 PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQ 1811 S PR +V +AT ++T+ W + + +++ P+ G+ Q TI S + Sbjct: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTIT 1871 Query: 1812 KLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871 L+P T Y I + +L + + T ++ NLR + ++L V W Sbjct: 1872 GLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARI 1930 Query: 1872 RQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVV 1914 Y + Y P E+VP P A + L+P T YT+ V+ Sbjct: 1931 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974 Score = 296 bits (757), Expect = 3e-79 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%) Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030 +G P+++ + + +E L P Y V++ A GE P Q P+ Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637 Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 2089 L +S+ +AW+ G V +YR+ YS + D I E P G + LQ L+P + Sbjct: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696 Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149 Y ++V+A+++D + L G ++ + P ++ + T W P + GY++ Sbjct: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755 Query: 2150 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207 P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814 Query: 2208 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263 + + ++ T + W + T +++ PA+G + T++ S+ TGL Sbjct: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874 Query: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292 P TDY + ++ N V + T + Sbjct: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903 Score = 277 bits (709), Expect = 1e-73 Identities = 256/949 (26%), Positives = 419/949 (44%), Gaps = 63/949 (6%) Query: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441 PG P N ++E T ++WTP +K+ P GG+ V+ S V+ Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140 Query: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496 L P EYV + V+ D E P+ T P +L++ D G T+ + Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556 TGY ++ P + +EV + + +L P EY V+V V D S P Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258 Query: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612 ++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672 S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375 Query: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731 W + ++ YRI P S + E + N++ NL P T Y VSI A+ E Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435 Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791 ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY + Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486 Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846 G Q T+ G +++ + LKP YTITV ++ GR +KP++ Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541 Query: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902 ++V D ++++V+W + Y++ P G GP + + + Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601 Query: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960 LQP Y VV VY + G + +T + + R + + +S+ + W+ G Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658 Query: 1961 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 2017 V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D E P Sbjct: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716 Query: 2018 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 2076 Q +P P +L+ T SLS W + + YR+ +P P+ E P Sbjct: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774 Query: 2077 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 2135 ++V++ L T Y+++V A+ + G T+ + PP+ ++D T +S Sbjct: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833 Query: 2136 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 2194 W + G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S Sbjct: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893 Query: 2195 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 2252 P+ +T ++L+ ++ V W P RA T Y +K P R R Sbjct: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953 Query: 2253 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301 T TGL P T+Y + V N + + + TV+ T T P Sbjct: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2001 Score = 256 bits (655), Expect = 2e-67 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%) Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 2258 T L + D+ + W SP + YR+ SP DG G E + Sbjct: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688 Query: 2259 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 2304 GL P ++Y V+V ++E P + + PT+ TP Sbjct: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735 Score = 217 bits (553), Expect = 1e-55 Identities = 171/613 (27%), Positives = 275/613 (44%), Gaps = 32/613 (5%) Query: 631 AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688 A PP DL F+ + + W+P ++ ++ + Y +++V + + S +VVL Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325 Query: 689 SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748 ++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383 Query: 749 RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807 + YRI + P G RE P ++ TL NL P T+Y VS++ L G Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443 Query: 808 AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866 +T V PRDL V T +++ +SW V+ Y +TY G QE TV G + Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501 Query: 867 NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922 + GLK G Y ++V A+ +G GD+ E P + D+ D SI Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559 Query: 923 AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982 W + V GYRV+ T K D IE LQP +Y +SV+A SG Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619 Query: 983 EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK 1042 E +PL A T + + K L + +++++ W+ G+V YRV Y G + Sbjct: 1620 ESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678 Query: 1043 VPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101 P T L+ L+P + Y ++V+ ++ E + G+ +TA +P +LK + T + Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736 Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161 S W P ++ GY+V P + E+ + P ++VV+ L T Y+V+V+ + Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796 Query: 1162 DGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSW 1208 D S P G +T ++TT+ + E +T + D V +G Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PANGQT 1855 Query: 1209 SIGRANFRTVRSF 1221 I R VRS+ Sbjct: 1856 PIQRTIKPDVRSY 1868 Score = 201 bits (510), Expect = 1e-50 Identities = 157/551 (28%), Positives = 237/551 (43%), Gaps = 20/551 (3%) Query: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693 P+DL T +W V Y ITY E G+ V P S ++ +S LKP Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510 Query: 694 ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749 Y + V A G S P++ TE K P ++VTD +S + W + Sbjct: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 750 VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808 V YR+ P G G ++ T P+Q T+E L P +Y VSV + SG PL A Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 809 ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYT-PVAGGETQEVTVRGDTTN 867 T R P+ L +D ++K++W G+V +Y VTY+ P G G+ Sbjct: 1629 VTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686 Query: 868 TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927 LQGL+ G++Y +SV AL+ L G +T +P DL +T TS+ A WT Sbjct: 1687 AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTP 1744 Query: 928 APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987 + GYRV E NL D+ ++ L TKY +SV+A + P Sbjct: 1745 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1804 Query: 988 TGDATT-ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046 G TT E + +V + TE T+ ++W+ + ++V P + + P Sbjct: 1805 QGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1864 Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106 V S + LQP T Y I + + +TA +P NL+ T +S V+ Sbjct: 1865 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA--IDAPSNLRFLATTPNSLLVS 1922 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTV--VLEELRAGTTYKVNVFGMFDGG 1164 W+P + GY + + G R E+V P + L GT Y + V + + Sbjct: 1923 WQPPRARITGYIIKYEKPGSPPR--EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980 Query: 1165 ESSPLVGQEMT 1175 +S PL+G++ T Sbjct: 1981 KSEPLIGRKKT 1991 Score = 200 bits (508), Expect = 2e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 194 bits (492), Expect = 1e-48 Identities = 209/874 (23%), Positives = 361/874 (41%), Gaps = 76/874 (8%) Query: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390 + V P +L +EV+ V + W P S VTGY+V + P+ G L + + T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963 Query: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450 V LS Y V A+ S+P++ + T+ +D ++ F V+ + S Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 + + RA +I+ R+ + L T + + ++ +++ + Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570 P R N A Y + + KG++ + PK + T + + ++ + + Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104 Query: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625 I +G K VR A + ++ + + T + ++ A Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164 Query: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678 I K P P +L G T +W ++ Y IT G + + V Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 A +S +L P Y V+V +D S+P++ +T P +L+ T+ D+ Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282 Query: 739 FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796 ++TW P + + + Y PV E E++ P+ L NL+P T+Y VSV Y Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342 Query: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855 TPL G T +P + SD T ++ + W + Y + + P G Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400 Query: 856 TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915 +E V + L L GT+Y +S+ AL L G+ +T+ + P+DL Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458 Query: 916 ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975 T TS+ W + VR YR+++ + E +P I L+P Y I+V Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 976 FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031 +A G+ +P++ + TE+ + S+ ++V + +N++ V W P+ V YRV Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089 P +G G P T ++ LQP Y ++V GE + L Q + T R Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--- 1634 Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP--YDNTVVLEEL 1147 P+ L +D + S ++ WE G+V Y+VT+ D + EL P ++T L+ L Sbjct: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGL 1692 Query: 1148 RAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 R G+ Y V+V + D ES PL+G + T + T Sbjct: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726 Score = 173 bits (438), Expect = 3e-42 Identities = 209/923 (22%), Positives = 360/923 (39%), Gaps = 128/923 (13%) Query: 334 VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392 V PP++L + +++ W P PS +T + V +P+ LS+ P + + Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 393 DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450 +L TEY +SVS++ S P+ +KT G+D I F + S++ Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAI 507 + +++ RA + + I + S + R PH+ TL T + + +I Sbjct: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428 Query: 508 NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565 R S + + + + S+VP+ + ++ +S ++ PA+ +R Sbjct: 1429 VALNGREES------------PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476 Query: 566 -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614 NS V+ F V +S P + TV + S ++ Sbjct: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532 Query: 615 SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672 I + E+ P + ++V W P+ V Y +T K G Sbjct: 1533 PISINYRTEID--------KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584 Query: 673 DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732 + P T + + L+P Y+V+V A+ G S PL T + P+ L T Sbjct: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1641 Query: 733 DETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVS 791 D DS KI W G+V RYR+ Y G P + L+ L P ++Y VS Sbjct: 1642 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701 Query: 792 VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP- 850 V+ + PL G +T P DL+ + T +++ W+ ++ Y V TP Sbjct: 1702 VVALHDDMESQPLIGTQST--AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759 Query: 851 VAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD 910 G +E+ + D+++ V+ GL T+Y +SV AL + G TTLE P+ Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819 Query: 911 LVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETK 970 D T+T+I W + + G++V ++ + D I LQP T Sbjct: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTD 1878 Query: 971 YRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY 1030 Y+I ++ + P+ DA+T + S L+ T N++ V+W+P ++ Y + Y Sbjct: 1879 YKIYLYTLNDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKY 1937 Query: 1031 -RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVL----------------------- 1066 +P +++V + P VT + L+P T Y I V+ Sbjct: 1938 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997 Query: 1067 ---PIYKMGEG-KLRQGSGTTAS-----RFKSPRNLKTSDPT------------------ 1099 P Y G G +L SG S F+ +T+ PT Sbjct: 1998 VTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ 2057 Query: 1100 --MSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNV 1157 +S ++W P + Y ++ HP G D + V + L L G TY + V Sbjct: 2058 EALSQTTISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2116 Query: 1158 FGMFDGGESSPLVGQEMTTLSDT 1180 + D + V +E+ T+ ++ Sbjct: 2117 EALKD--QQRHKVREEVVTVGNS 2137 Score = 161 bits (407), Expect = 1e-38 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%) Query: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669 E +S + I+QE + VP P+DL F EVT W+P V Y + Sbjct: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944 Query: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 E P S +T ++ L P Y V A S PL ++TT+ AP N Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002 Query: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788 L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062 Query: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848 VS++ + TG T + G+ ++ T +T+ ++W+ AP + + Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119 Query: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907 P GGE +EVT D+ + V+ GL G +Y ++ L DA + Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176 Query: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960 P +L + DT + ++ S + GYR++ + + N E+ +H Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232 Query: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020 +NL P +Y +SV+ E P++ D L+ +TMRVTW P P Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291 Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077 + N+ V Y P + ++ VA+ + P+ + VL L P T Y ++V +Y+ E Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350 Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137 +G T SP + SD T +SF V W + GY++ HP R E V Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408 Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179 N++ L L GT Y V++ + +G E SPL+ + +T+SD Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449 Score = 155 bits (391), Expect = 8e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 Score = 147 bits (370), Expect = 2e-34 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%) Query: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 EQ L + P P D + +V WS + Y I Y + + Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733 P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ + Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917 Query: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792 T I WT V YR+ PV GE + + L P Y V Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977 Query: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852 PLT T+ P +L+ + T ST+ + W+ ++ Y +T Sbjct: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035 Query: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970 ++T+T+I WT AP R+ +K GE + + D+ ++ L P + Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148 Query: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028 Y ++ E + P+ T LS + + V+W + + YR+ Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208 Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086 P +G + V +S L P Y+++V + E S T Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266 Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145 P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P DN VVL Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 L GT Y V+V +++ ES+PL G++ T L T Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362 Score = 105 bits (263), Expect = 5e-22 Identities = 119/490 (24%), Positives = 188/490 (38%), Gaps = 49/490 (10%) Query: 622 QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679 Q L + A P DL F++VT W+P + Y +T KE G + + Sbjct: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771 Query: 680 PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739 P SS SVV+S L T Y V+V A + S P G TT E PR +VTD T + Sbjct: 1772 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1830 Query: 740 KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799 I+W + +++ P G + T P+ R T+ L P T Y++ + + Sbjct: 1831 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1890 Query: 800 PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859 +P+ +A+T P +LR T +++ +SW ++ Y++ Y G +EV Sbjct: 1891 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 1947 Query: 860 T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917 R T + GL+ GT+Y + V AL + + L G T+++ VT Sbjct: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQK----TPFVTHPGY 2003 Query: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977 DT G G G++ + E+ H P T A Sbjct: 2004 DTGNGIQLPGTSG-------------QQPSVGQQMIFEE--HGFRRTTPPTT-------A 2041 Query: 978 TYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGK 1037 T P + V +E + ++W P Y + P G + Sbjct: 2042 TPIRHRPRPYPPN-------------VGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDE 2087 Query: 1038 Q-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTS 1096 + + +VP T TS L L TY+I V + K+R+ T + N T Sbjct: 2088 EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTD 2147 Query: 1097 DPTMSSFRVT 1106 D + V+ Sbjct: 2148 DSCFDPYTVS 2157 Score = 66.6 bits (161), Expect = 4e-10 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Query: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73 +L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859 Query: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133 + LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916 Query: 134 SVS 136 V+ Sbjct: 917 EVT 919 Score = 59.7 bits (143), Expect = 4e-08 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82 E+D PS + + +N++ + W P+ GYR+T P GPTK T TE + Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600 Query: 83 ELVPETEYVVTITSYDEVEESVPVI 107 L P EYVV++ + + ES P++ Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPLV 1625 Score = 58.9 bits (141), Expect = 7e-08 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 ++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L Sbjct: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 L P +EY V++ + +ES G T+Q GSS P + +T I V WT Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108 Score = 53.5 bits (127), Expect = 3e-06 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82 V PP+DL F I +T+ ++WA P + + + P + E ++S S +L+ Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 83 ELVPETEYVVTITSYDEVEESVPVIGQ 109 L+P TEYVV+++S E ES P+ G+ Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353 Score = 50.1 bits (118), Expect = 3e-05 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 +D P+ ++F I N+ + W P I GYRI P G +E + S L+ Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEYVV+I + + EES +IGQ Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443 Score = 50.1 bits (118), Expect = 3e-05 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76 L+ + +D P L F +D +++ ++W P + YR+T DG + F Sbjct: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683 Query: 77 TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135 +T L L P +EY V++ + + ES P+IG T S+ P T++ S+ Sbjct: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1738 Query: 136 SA-WT 139 SA WT Sbjct: 1739 SAQWT 1743 Score = 48.9 bits (115), Expect = 8e-05 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75 L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+ Sbjct: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773 Query: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111 ++ ++S L+ T+Y V++ + + S P G +T Sbjct: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809 Score = 47.8 bits (112), Expect = 2e-04 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 5/117 (4%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEP-PSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPM 371 +S V D + L+ + P P++L +V+ + W P +TGY+V +TP Sbjct: 1700 VSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759 Query: 372 TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP----ISIMEKTQP 424 +++ P ++++ V L T+Y++SV A+K +S P ++ +E P Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816 Score = 45.1 bits (105), Expect = 0.001 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372 + Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849 Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 GS L++ ++++ DL +Y I++ A++ S P+ I ++T Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898 Score = 45.1 bits (105), Expect = 0.001 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70 A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106 + A + L P EY V++ + + +ESVP+ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259 Score = 44.7 bits (104), Expect = 0.001 Identities = 25/96 (26%), Positives = 44/96 (45%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 ++ ++ PSNL + + + ++W P + +TGY + + R+ P Sbjct: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 T ++ L TEY I V A+K SEP+ +KT Sbjct: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1991 Score = 44.3 bits (103), Expect = 0.002 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%) Query: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 LL+ D P DL ++ +SW P + YRIT T + P +EFT+ Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498 Query: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130 S + +S L P +Y +T+ + TG P KP +TEI Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542 Query: 131 QKCSVSAWTDL 141 K S TD+ Sbjct: 1543 DKPSQMQVTDV 1553 Score = 43.1 bits (100), Expect = 0.004 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 9/102 (8%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83 +D PS+L F N++ +SW P I GY I + P + TE ++ Sbjct: 1903 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP 125 L P TEY + + + ++S P+IG+ K V+K P Sbjct: 1963 LEPGTEYTIYVIALKNNQKSEPLIGR--------KKTVQKTP 1996 Score = 36.2 bits (82), Expect = 0.51 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64 L L + A +++++E V PP E T+ +SW + I G+++ P Sbjct: 1795 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1853 Query: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107 + T+ ++ L P T+Y + + + ++ S PV+ Sbjct: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896 Score = 36.2 bits (82), Expect = 0.51 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 +V+ E V PP + + + ++W +TG++V P G ++ P Sbjct: 1807 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1865 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446 + ++ L T+Y+I + + S P V ++ S +D +++ FL Sbjct: 1866 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1914 Query: 447 GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494 S+ + ++ RA + + +E P +V R TE T+ Sbjct: 1915 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1960 Score = 35.0 bits (79), Expect = 1.1 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 V P DL F + + V + W P + GYR+ V P G + + T ++ Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118 L P Y + + ES P+ Q T + + T Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001 Score = 33.5 bits (75), Expect = 3.3 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101 +SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797 Query: 102 ESVPVIGQLTIQTGSSTKP 120 E L + T +T P Sbjct: 798 EQ-----SLILSTSQTTAP 811 Score = 32.7 bits (73), Expect = 5.7 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%) Query: 312 IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370 ++S V E+ L+ + V + P +L + + + ++W+ V Y++ Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484 Query: 371 MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423 S +V +T ++ L +Y I+V A+ G SS+PISI +T+ Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544 Query: 424 PMKVQV 429 P ++QV Sbjct: 1545 PSQMQV 1550 >gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] Length = 2355 Score = 383 bits (983), Expect = e-105 Identities = 357/1427 (25%), Positives = 593/1427 (41%), Gaps = 119/1427 (8%) Query: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876 + W+ P + +Y++ + P G +E T+ G + ++GLK G Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687 Query: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931 T++ + T+ + + GE T + + VT +IT +S W SA Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746 Query: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991 V G+RV ++ + + +LP A I +L P KY ++V+ GE + + Sbjct: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806 Query: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051 T VD+ + ++ V W + YR+VY P G +P T S Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866 Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106 L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T + Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166 W P V GY+V P G+ + + + L G TY VF + G ES Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225 PL Q+ T L T + ++ E D +LV W+ RA R + Sbjct: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035 Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270 +++GP + L P +E+ ++ K + LQ +++P Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093 Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330 Y T T + + + + G+RP EAP + D G Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136 Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390 + + P + Y + + R + + N V P L P+N Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179 Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446 L + VSW + + Y++ P +G G E V ++S +L P Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239 Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504 EY V+VY+V +D+ S P+ T P L ++GP TM V W P T ++ Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299 Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564 + Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V S P+ R+ T Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356 Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621 L P + D+T ++ V W + Y +R+ PE +E V S S +L Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415 Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681 +L T Y VS+ A++ ESP + Q++T P +L++ T +WD A Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474 Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 V YRIT+ G +S E + G ++T L P Y +++ A+ + D S Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530 Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799 + + I T+ K P +QV + NS++VKW P+S V YR+T P G G +T Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588 Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859 T G Q + ++ L+P Y ++V + P GE + T ++ + L D + Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDS 1647 Query: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVVPVYT 1918 + + W+ +G +Y++ Y+ G EL P P G + A L+ L+P + YTV+VV ++ Sbjct: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707 Query: 1919 EGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSE 1978 + + T T + +++ TP SL +W P + YRV +P + T P + Sbjct: 1708 DMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766 Query: 1979 SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGET 2037 I + ++ V + L+ T Y V++ AL P+ TL S PR RV T Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826 Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097 +++++W + +++ P G + T P R+ I LQP T YKI + Sbjct: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI-TGLQPGTDYKIYLYT 1885 Query: 2098 VYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS-- 2155 + ++ + + T + P N+ VSW P + + GY I Y+ GS Sbjct: 1886 LNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1944 Query: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 2202 E + +T T+ L P T Y + V A ++ S PL + T Sbjct: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1991 Score = 334 bits (856), Expect = 9e-91 Identities = 325/1304 (24%), Positives = 551/1304 (42%), Gaps = 84/1304 (6%) Query: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697 S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y Sbjct: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786 Query: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756 +VNV EDG S+ L+ +TT AP + V S + W++ + YRI+ Sbjct: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844 Query: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810 Y P G S E+ P TL +L P +Y +++ + TP+ TG + Sbjct: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868 + V +PRDL+ + T + + W+ V Y V PV G Q + + +T Sbjct: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963 Query: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928 V GL G Y V A+ L + TT + +P +L + TD+++ WT Sbjct: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020 Query: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988 + GYR++ L + N+ + NLQP ++Y +S+ A + E T Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079 Query: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048 G TT S E TE T+ +TW PAP + +++ RP +G + +V Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136 Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107 S V+ L P Y T+ + + G+ + + P NL ++P V+W Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195 Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165 E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255 Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225 S P+ + + T + + G + + A SI NF S + Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308 Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280 +V ++ A+ + P TE+ ++ S+ + + P +G ++ TG+ Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364 Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340 + I +F T + PRA G I ++ + + E Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423 Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400 + ++A + + + ++S + P +L + T S Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463 Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458 +SW P+ +V Y++ Y G QEF V +++ + LKP +Y + VY+V Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523 Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514 S+P+ +T + + DV ++ V+W P TGY ++ P Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583 Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574 PT+ K GP +M + L P EY V+V A S+P+ VT + RP+ L Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAF 1640 Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EVDRSETSTSLKDLFSQTLYTV 1632 DV ++ + WE G+V +Y V Y +PE+ + E+ D E + L+ L + YTV Sbjct: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTV 1700 Query: 1633 SVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPF 1692 SV A+HD+ ES P+ ++T +PAPT+LK T+VT W ++ YR+ P Sbjct: 1701 SVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759 Query: 1693 GSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQA 1751 + M+ I L D +++V L T YEVS+ A+ D + S ++TT Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL-------KDTLTSRPAQGVVTTLE 1812 Query: 1752 PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQ 1811 S PR +V +AT ++T+ W + + +++ P+ G+ Q TI S + Sbjct: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTIT 1871 Query: 1812 KLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871 L+P T Y I + +L + + T ++ NLR + ++L V W Sbjct: 1872 GLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARI 1930 Query: 1872 RQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVV 1914 Y + Y P E+VP P A + L+P T YT+ V+ Sbjct: 1931 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974 Score = 296 bits (757), Expect = 3e-79 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%) Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030 +G P+++ + + +E L P Y V++ A GE P Q P+ Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637 Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 2089 L +S+ +AW+ G V +YR+ YS + D I E P G + LQ L+P + Sbjct: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696 Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149 Y ++V+A+++D + L G ++ + P ++ + T W P + GY++ Sbjct: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755 Query: 2150 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207 P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814 Query: 2208 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263 + + ++ T + W + T +++ PA+G + T++ S+ TGL Sbjct: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874 Query: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292 P TDY + ++ N V + T + Sbjct: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903 Score = 276 bits (705), Expect = 3e-73 Identities = 253/942 (26%), Positives = 416/942 (44%), Gaps = 62/942 (6%) Query: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441 PG P N ++E T ++WTP +K+ P GG+ V+ S V+ Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140 Query: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496 L P EYV + V+ D E P+ T P +L++ D G T+ + Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556 TGY ++ P + +EV + + +L P EY V+V V D S P Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258 Query: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612 ++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672 S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375 Query: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731 W + ++ YRI P S + E + N++ NL P T Y VSI A+ E Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435 Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791 ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY + Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486 Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846 G Q T+ G +++ + LKP YTITV ++ GR +KP++ Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541 Query: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902 ++V D ++++V+W + Y++ P G GP + + + Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601 Query: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960 LQP Y VV VY + G + +T + + R + + +S+ + W+ G Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658 Query: 1961 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 2017 V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D E P Sbjct: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716 Query: 2018 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 2076 Q +P P +L+ T SLS W + + YR+ +P P+ E P Sbjct: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774 Query: 2077 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 2135 ++V++ L T Y+++V A+ + G T+ + PP+ ++D T +S Sbjct: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833 Query: 2136 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 2194 W + G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S Sbjct: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893 Query: 2195 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 2252 P+ +T ++L+ ++ V W P RA T Y +K P R R Sbjct: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953 Query: 2253 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294 T TGL P T+Y + V N + + ++ T P Sbjct: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995 Score = 256 bits (655), Expect = 2e-67 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%) Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 2258 T L + D+ + W SP + YR+ SP DG G E + Sbjct: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688 Query: 2259 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 2304 GL P ++Y V+V ++E P + + PT+ TP Sbjct: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735 Score = 219 bits (559), Expect = 2e-56 Identities = 236/938 (25%), Positives = 396/938 (42%), Gaps = 77/938 (8%) Query: 631 AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688 A PP DL F+ + + W+P ++ ++ + Y +++V + + S +VVL Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325 Query: 689 SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748 ++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383 Query: 749 RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807 + YRI + P G RE P ++ TL NL P T+Y VS++ L G Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443 Query: 808 AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866 +T V PRDL V T +++ +SW V+ Y +TY G QE TV G + Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501 Query: 867 NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922 + GLK G Y ++V A+ +G GD+ E P + D+ D SI Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559 Query: 923 AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982 W + V GYRV+ T K D IE LQP +Y +SV+A SG Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619 Query: 983 EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK 1042 E +PL A T + + K L + +++++ W+ G+V YRV Y G + Sbjct: 1620 ESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678 Query: 1043 VPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101 P T L+ L+P + Y ++V+ ++ E + G+ +TA +P +LK + T + Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736 Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161 S W P ++ GY+V P + E+ + P ++VV+ L T Y+V+V+ + Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796 Query: 1162 DGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSW 1208 D S P G +T ++TT+ + E +T + D V +G Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PANGQT 1855 Query: 1209 SIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVA 1267 I R VRS+ I+ + D K L + + D S L+ +A Sbjct: 1856 PIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLA 1913 Query: 1268 NLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320 P +TG + + + + + RPR IT + + Sbjct: 1914 TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973 Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT---INLCN 1377 LK+ IG K DE+ +++ + H + D S + +T + N Sbjct: 1974 IALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGN 2032 Query: 1378 SVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVS 1433 ++ PG + PS ++ E FR + P + + R++ YP + G+ + Sbjct: 2033 GIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYPPNVGQE-----A 2084 Query: 1434 RMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQ 1493 +T+ + +EY+++ + V DE EPL+ VP S + G T Sbjct: 2085 LSQTTISWAPFQDTSEYIISCHPVGTDE--EPLQ-----FRVPGTSTSATLTGLTR---- 2133 Query: 1494 WQPVGGATGYILSYKPVKDTEPTRPKE--VRLGPTVND 1529 GAT Y + + +KD + + +E V +G +VN+ Sbjct: 2134 -----GAT-YNIIVEALKDQQRHKVREEVVTVGNSVNE 2165 Score = 200 bits (508), Expect = 2e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 194 bits (492), Expect = 1e-48 Identities = 209/874 (23%), Positives = 361/874 (41%), Gaps = 76/874 (8%) Query: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390 + V P +L +EV+ V + W P S VTGY+V + P+ G L + + T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963 Query: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450 V LS Y V A+ S+P++ + T+ +D ++ F V+ + S Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 + + RA +I+ R+ + L T + + ++ +++ + Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570 P R N A Y + + KG++ + PK + T + + ++ + + Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104 Query: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625 I +G K VR A + ++ + + T + ++ A Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164 Query: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678 I K P P +L G T +W ++ Y IT G + + V Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 A +S +L P Y V+V +D S+P++ +T P +L+ T+ D+ Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282 Query: 739 FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796 ++TW P + + + Y PV E E++ P+ L NL+P T+Y VSV Y Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342 Query: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855 TPL G T +P + SD T ++ + W + Y + + P G Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400 Query: 856 TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915 +E V + L L GT+Y +S+ AL L G+ +T+ + P+DL Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458 Query: 916 ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975 T TS+ W + VR YR+++ + E +P I L+P Y I+V Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 976 FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031 +A G+ +P++ + TE+ + S+ ++V + +N++ V W P+ V YRV Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089 P +G G P T ++ LQP Y ++V GE + L Q + T R Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--- 1634 Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP--YDNTVVLEEL 1147 P+ L +D + S ++ WE G+V Y+VT+ D + EL P ++T L+ L Sbjct: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGL 1692 Query: 1148 RAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 R G+ Y V+V + D ES PL+G + T + T Sbjct: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726 Score = 170 bits (430), Expect = 2e-41 Identities = 178/759 (23%), Positives = 310/759 (40%), Gaps = 73/759 (9%) Query: 334 VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392 V PP++L + +++ W P PS +T + V +P+ LS+ P + + Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 393 DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450 +L TEY +SVS++ S P+ +KT G+D I F + S++ Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAI 507 + +++ RA + + I + S + R PH+ TL T + + +I Sbjct: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428 Query: 508 NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565 R S + + + + S+VP+ + ++ +S ++ PA+ +R Sbjct: 1429 VALNGREES------------PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476 Query: 566 -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614 NS V+ F V +S P + TV + S ++ Sbjct: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532 Query: 615 SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672 I + E+ P + ++V W P+ V Y +T K G Sbjct: 1533 PISINYRTEID--------KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584 Query: 673 DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732 + P T + + L+P Y+V+V A+ G S PL T + P+ L T Sbjct: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1641 Query: 733 DETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVS 791 D DS KI W G+V RYR+ Y G P + L+ L P ++Y VS Sbjct: 1642 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701 Query: 792 VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP- 850 V+ + PL G +T P DL+ + T +++ W+ ++ Y V TP Sbjct: 1702 VVALHDDMESQPLIGTQST--AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759 Query: 851 VAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD 910 G +E+ + D+++ V+ GL T+Y +SV AL + G TTLE P+ Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819 Query: 911 LVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETK 970 D T+T+I W + + G++V ++ + D I LQP T Sbjct: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTD 1878 Query: 971 YRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY 1030 Y+I ++ + P+ DA+T + S L+ T N++ V+W+P ++ Y + Y Sbjct: 1879 YKIYLYTLNDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKY 1937 Query: 1031 -RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPI 1068 +P +++V + P VT + L+P T Y I V+ + Sbjct: 1938 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1976 Score = 161 bits (407), Expect = 1e-38 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%) Query: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669 E +S + I+QE + VP P+DL F EVT W+P V Y + Sbjct: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944 Query: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 E P S +T ++ L P Y V A S PL ++TT+ AP N Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002 Query: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788 L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062 Query: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848 VS++ + TG T + G+ ++ T +T+ ++W+ AP + + Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119 Query: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907 P GGE +EVT D+ + V+ GL G +Y ++ L DA + Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176 Query: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960 P +L + DT + ++ S + GYR++ + + N E+ +H Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232 Query: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020 +NL P +Y +SV+ E P++ D L+ +TMRVTW P P Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291 Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077 + N+ V Y P + ++ VA+ + P+ + VL L P T Y ++V +Y+ E Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350 Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137 +G T SP + SD T +SF V W + GY++ HP R E V Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408 Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179 N++ L L GT Y V++ + +G E SPL+ + +T+SD Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449 Score = 155 bits (391), Expect = 8e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 Score = 147 bits (370), Expect = 2e-34 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%) Query: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 EQ L + P P D + +V WS + Y I Y + + Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733 P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ + Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917 Query: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792 T I WT V YR+ PV GE + + L P Y V Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977 Query: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852 PLT T+ P +L+ + T ST+ + W+ ++ Y +T Sbjct: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035 Query: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970 ++T+T+I WT AP R+ +K GE + + D+ ++ L P + Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148 Query: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028 Y ++ E + P+ T LS + + V+W + + YR+ Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208 Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086 P +G + V +S L P Y+++V + E S T Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266 Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145 P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P DN VVL Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 L GT Y V+V +++ ES+PL G++ T L T Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362 Score = 105 bits (262), Expect = 7e-22 Identities = 125/491 (25%), Positives = 193/491 (39%), Gaps = 26/491 (5%) Query: 622 QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679 Q L + A P DL F++VT W+P + Y +T KE G + + Sbjct: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771 Query: 680 PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739 P SS SVV+S L T Y V+V A + S P G TT E PR +VTD T + Sbjct: 1772 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1830 Query: 740 KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799 I+W + +++ P G + T P+ R T+ L P T Y++ + + Sbjct: 1831 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1890 Query: 800 PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859 +P+ +A+T P +LR T +++ +SW ++ Y++ Y G +EV Sbjct: 1891 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 1947 Query: 860 T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917 R T + GL+ GT+Y + V AL + + L G T E PQ LVT Sbjct: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE---LPQ-LVTLPHP 2003 Query: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEK-NLPEDAIHTMIENLQPETKYRISVF 976 + G P V+ Y DTG LP + QP ++ +F Sbjct: 2004 NLH-GPEILDVPSTVQKTPFVTHPGY---DTGNGIQLPGTS------GQQPSVGQQM-IF 2052 Query: 977 ATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRG 1036 + P T V +E + ++W P Y + P G Sbjct: 2053 EEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIISCHPVGTD 2111 Query: 1037 KQ-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKT 1095 ++ + +VP T TS L L TY+I V + K+R+ T + N T Sbjct: 2112 EEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPT 2171 Query: 1096 SDPTMSSFRVT 1106 D + V+ Sbjct: 2172 DDSCFDPYTVS 2182 Score = 85.9 bits (211), Expect = 6e-16 Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 61/497 (12%) Query: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393 ++ PS + +V + + W PS SPVTGY+V TP + GP T +++ Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601 Query: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGV---DIKADIVFLVDGSYS 450 L EY +SV A S+P+ Q ++ +G+ D+ D + + S Sbjct: 1602 LQPTVEYVVSVYAQNPSGESQPL-----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ 1656 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 ++ + + E + +P+ + + P +E+T+ +D + + Sbjct: 1657 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD----MESQ 1712 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK------VMILITDGKSSDAFRDPAIKL 564 P G + A T ++ P+ S P + +T + + ++ I L Sbjct: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE--INL 1770 Query: 565 RNSDVEIFAVGVKDAVRSEL------EAIASPPAETHVFTVEDFDAFQRISFELTQSICL 618 + G+ A + E+ + + S PA+ V T+E+ Sbjct: 1771 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS--------------- 1815 Query: 619 RIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 PP+ ++ T +W E + + + A G + Sbjct: 1816 ---------------PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 S ++ L+P T Y + + ++ S P+ + +T AP NL+ T +S Sbjct: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST--AIDAPSNLRFLATTPNS 1918 Query: 739 FKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQ--RRRTLENLIPDTKYEVSVIPEY 796 ++W R+ Y I Y G REV P T+ L P T+Y + VI Sbjct: 1919 LLVSWQPPRARITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK 1977 Query: 797 FSGPGTPLTGNAATEEV 813 + PL G T+E+ Sbjct: 1978 NNQKSEPLIGRKKTDEL 1994 Score = 76.6 bits (187), Expect = 3e-13 Identities = 84/359 (23%), Positives = 144/359 (40%), Gaps = 55/359 (15%) Query: 1384 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 1443 ++ P +++ T + +SW ++++ ++V+ P +G + + S + Sbjct: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1872 Query: 1444 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 1502 L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG Sbjct: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1932 Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 1561 YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+ Sbjct: 1933 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990 Query: 1562 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 1614 VTLP P ++ DV + + PG Y T ++ Sbjct: 1991 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2041 Query: 1615 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRG 1673 + S + +F + + +PP TA RP P P N+ Sbjct: 2042 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNV------------ 2080 Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFENLNPNTIYEVSITAI 1727 G +S I+WAPF D E I++ DE L F P T ++T + Sbjct: 2081 ----GQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR--VPGTSTSATLTGL 2131 Score = 66.6 bits (161), Expect = 4e-10 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Query: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73 +L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859 Query: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133 + LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916 Query: 134 SVS 136 V+ Sbjct: 917 EVT 919 Score = 59.7 bits (143), Expect = 4e-08 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82 E+D PS + + +N++ + W P+ GYR+T P GPTK T TE + Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600 Query: 83 ELVPETEYVVTITSYDEVEESVPVI 107 L P EYVV++ + + ES P++ Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPLV 1625 Score = 58.9 bits (141), Expect = 7e-08 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 ++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L Sbjct: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 L P +EY V++ + +ES G T+Q GSS P + +T I V WT Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108 Score = 53.5 bits (127), Expect = 3e-06 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82 V PP+DL F I +T+ ++WA P + + + P + E ++S S +L+ Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 83 ELVPETEYVVTITSYDEVEESVPVIGQ 109 L+P TEYVV+++S E ES P+ G+ Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353 Score = 50.1 bits (118), Expect = 3e-05 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 +D P+ ++F I N+ + W P I GYRI P G +E + S L+ Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEYVV+I + + EES +IGQ Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443 Score = 50.1 bits (118), Expect = 3e-05 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76 L+ + +D P L F +D +++ ++W P + YR+T DG + F Sbjct: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683 Query: 77 TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135 +T L L P +EY V++ + + ES P+IG T S+ P T++ S+ Sbjct: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1738 Query: 136 SA-WT 139 SA WT Sbjct: 1739 SAQWT 1743 Score = 48.9 bits (115), Expect = 8e-05 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75 L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+ Sbjct: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773 Query: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111 ++ ++S L+ T+Y V++ + + S P G +T Sbjct: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809 Score = 47.8 bits (112), Expect = 2e-04 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 5/117 (4%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEP-PSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPM 371 +S V D + L+ + P P++L +V+ + W P +TGY+V +TP Sbjct: 1700 VSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759 Query: 372 TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP----ISIMEKTQP 424 +++ P ++++ V L T+Y++SV A+K +S P ++ +E P Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816 Score = 45.1 bits (105), Expect = 0.001 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372 + Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849 Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 GS L++ ++++ DL +Y I++ A++ S P+ I ++T Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898 Score = 45.1 bits (105), Expect = 0.001 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70 A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106 + A + L P EY V++ + + +ESVP+ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259 Score = 45.1 bits (105), Expect = 0.001 Identities = 25/99 (25%), Positives = 45/99 (45%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 ++ ++ PSNL + + + ++W P + +TGY + + R+ P Sbjct: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425 T ++ L TEY I V A+K SEP+ +KT + Sbjct: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1994 Score = 44.3 bits (103), Expect = 0.002 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%) Query: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 LL+ D P DL ++ +SW P + YRIT T + P +EFT+ Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498 Query: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130 S + +S L P +Y +T+ + TG P KP +TEI Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542 Query: 131 QKCSVSAWTDL 141 K S TD+ Sbjct: 1543 DKPSQMQVTDV 1553 Score = 42.7 bits (99), Expect = 0.005 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83 +D PS+L F N++ +SW P I GY I + P + TE ++ Sbjct: 1903 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEY + + + ++S P+IG+ Sbjct: 1963 LEPGTEYTIYVIALKNNQKSEPLIGR 1988 Score = 36.2 bits (82), Expect = 0.51 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64 L L + A +++++E V PP E T+ +SW + I G+++ P Sbjct: 1795 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1853 Query: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107 + T+ ++ L P T+Y + + + ++ S PV+ Sbjct: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896 Score = 36.2 bits (82), Expect = 0.51 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 +V+ E V PP + + + ++W +TG++V P G ++ P Sbjct: 1807 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1865 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446 + ++ L T+Y+I + + S P V ++ S +D +++ FL Sbjct: 1866 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1914 Query: 447 GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494 S+ + ++ RA + + +E P +V R TE T+ Sbjct: 1915 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1960 Score = 35.0 bits (79), Expect = 1.1 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 V P DL F + + V + W P + GYR+ V P G + + T ++ Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118 L P Y + + ES P+ Q T + + T Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001 Score = 33.5 bits (75), Expect = 3.3 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101 +SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797 Query: 102 ESVPVIGQLTIQTGSSTKP 120 E L + T +T P Sbjct: 798 EQ-----SLILSTSQTTAP 811 Score = 32.7 bits (73), Expect = 5.7 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%) Query: 312 IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370 ++S V E+ L+ + V + P +L + + + ++W+ V Y++ Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484 Query: 371 MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423 S +V +T ++ L +Y I+V A+ G SS+PISI +T+ Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544 Query: 424 PMKVQV 429 P ++QV Sbjct: 1545 PSQMQV 1550 >gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] Length = 957 Score = 382 bits (981), Expect = e-105 Identities = 291/935 (31%), Positives = 389/935 (41%), Gaps = 214/935 (22%) Query: 2314 RDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVK 2373 R C+ A D+VF+ D S+S+G +NF V K++ N FD I P IQV VQYSD Sbjct: 28 RSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFD-IGPKFIQVGVVQYSDYPV 86 Query: 2374 SEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVT 2433 E L +Y+ A+++I Y GGNT+TGKA+ F + + S + + K+ VV+T Sbjct: 87 LEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSS---RFLTKIAVVLT 143 Query: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGV-ADVDYNELANIASKPSERHVFIVDDFESFEKI 2492 DG+SQD+VK AA + S ++F +GV ++ + EL IA+KPS +VF V+D+ + KI Sbjct: 144 DGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKI 203 Query: 2493 EDNLITFVCETATSSCPL-IYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYS 2551 + + +CE S CP I + GF +L ++ +K +Q S Sbjct: 204 REVMKQKLCEE--SVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQL------SPKKIK 255 Query: 2552 AYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVI 2611 Y + +++ T+++ P GLPPSY + R + D +W+I D +PQ+ V Sbjct: 256 GYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWD---LWRILTIDGRPQIAVT 312 Query: 2612 ADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIE 2671 + K L F Q VTF +VKTLF +H++ ++VT + V +YID +I Sbjct: 313 LNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIEN 372 Query: 2672 KDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDE-- 2729 K + I +G +GK G+ ++ F +Q I C P +R+ C+IP E Sbjct: 373 KPLHPVLGILINGQTQIGKY-SGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECL 431 Query: 2730 ---GKCPAFPNSCTCTQDSVGPPGP----------------------------------- 2751 + P C C G GP Sbjct: 432 NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG 491 Query: 2752 ----------PGPAGGPGAKGPRGERGISG---AIGPPGPRGDIGPPGPQGPPGPQGPNG 2798 PG G PG G +G+RG+ G G PG +G++G G +G PG G G Sbjct: 492 SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551 Query: 2799 LS----------IPG---EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 2845 +PG E GR G G G PG G G+PG PG G G PG GF G Sbjct: 552 AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611 Query: 2846 KDGAMGPRGPPGPP------------------GSPGSPGVTGPSGKPGKPGDHGRPGPSG 2887 G MG +G GPP GSPG PG G G G+PG G PG SG Sbjct: 612 NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671 Query: 2888 LKGEKGDRGDIASQNMMRAVARQ--------VCEQLISGQMNRFNQMLNQIPNDY----- 2934 LKGE G G M Q E+ I GQ + IP Sbjct: 672 LKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR--QGIPGQQGIQGH 729 Query: 2935 ------QSSRNQP------------------GPPGPPGPPGSAGARGEPGPGGRP----- 2965 + + +P GP GP G PG G +G PG G+P Sbjct: 730 HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFS 789 Query: 2966 --------------------------------------GFPGTPGMQGPPGERGLPGEKG 2987 G PG PG GP G RGLPG G Sbjct: 790 EQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPG 849 Query: 2988 ERGT-------GSSGPRGLPGPPGPQGE---------SRTGPPGSTGSRGPP-----GPP 3026 G G G RGL G PG GE GPPG G GPP GPP Sbjct: 850 RDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPP 909 Query: 3027 GRP---------GNSGIRGPPGPPGYCDSSQCASI 3052 G P G GI+G PGPPG CD S C S+ Sbjct: 910 GDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSV 944 Score = 198 bits (504), Expect = 6e-50 Identities = 129/352 (36%), Positives = 156/352 (44%), Gaps = 46/352 (13%) Query: 2747 GPPGPPGPAGGPGAKGPRGE---RGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIP 2802 G G G AG PG GP GE G G +G PG +G+ G PG G G +G G+ P Sbjct: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610 Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP 2862 G +G G KG+ G PG G+ G PG+PG G G PG G G G+ G G G PG+ Sbjct: 611 GNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGAS 670 Query: 2863 GSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC--EQLISGQM 2920 G G G +G PG+PG G PG G KG+KG++G+ Q RQ +Q I G Sbjct: 671 GLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHH 730 Query: 2921 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 2980 + + + +PG G G G +G G GP G G PG PG QGPPG Sbjct: 731 GAKGE---------RGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLD 781 Query: 2981 GLPGEKG-----------------------------ERGTGSSGPRGLPGPPGPQG-ESR 3010 G PG + + G G+PGPPGP G E Sbjct: 782 GKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841 Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG-QGYPG 3061 G PG G G PG G PG G+RG G PG Y G QG PG Sbjct: 842 RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPG 893 Score = 131 bits (329), Expect = 1e-29 Identities = 85/243 (34%), Positives = 132/243 (54%), Gaps = 28/243 (11%) Query: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTK 499 D+VF++DGSYS+G NF V+ +L + K+F+I P +Q+ +VQYS P E L + Sbjct: 37 DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96 Query: 500 VEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRD 559 E + A+ + Y GG+T TGKA+ + + +F +K SR + K+ +++TDGKS D +D Sbjct: 97 GEHLTAAVESILYLGGNTKTGKAIQFALDYLF--AKSSRF-LTKIAVVLTDGKSQDDVKD 153 Query: 560 PAIKLRNSDVEIFAVGV-KDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSIC- 617 A R+S + +FA+GV + +EL AIA+ P+ T+VF VED+ A +I + Q +C Sbjct: 154 AAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKLCE 213 Query: 618 -----------LRIEQEL---------AAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGE 657 R E+ +KK+ + PK + EVTS K + S Sbjct: 214 ESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQLSPKKIKGYEVTS---KVDLSELTS 270 Query: 658 NVF 660 NVF Sbjct: 271 NVF 273 Score = 128 bits (322), Expect = 8e-29 Identities = 72/209 (34%), Positives = 116/209 (55%), Gaps = 10/209 (4%) Query: 1196 AEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNA 1255 A D+V ++DGS+S+G NF V+ ++ I + FDIGPK +Q+ + QYS P E L + Sbjct: 34 APTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGS 93 Query: 1256 HRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDD 1315 + + L AV ++ Y GGNT TG A+ F F + KI V++TDGKSQDD Sbjct: 94 YDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRF---LTKIAVVLTDGKSQDD 150 Query: 1316 VEAPSKKLKDEGVELFAIGI-KNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTIN 1374 V+ ++ +D + LFAIG+ ++ EL+ IA P T+ + V D+ ++S+I + + Sbjct: 151 VKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQK 210 Query: 1375 LCNSVKGPGDLEAPSNLVISERTHRSFRV 1403 LC + P+ + ++ R R F + Sbjct: 211 LCE------ESVCPTRIPVAARDERGFDI 233 Score = 128 bits (321), Expect = 1e-28 Identities = 83/241 (34%), Positives = 135/241 (56%), Gaps = 10/241 (4%) Query: 129 EIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDT 188 E++ +A TDLVF++DGS+SVG NF+ + ++ + FDIG + +VGVVQYS Sbjct: 26 EVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYP 85 Query: 189 RTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIII 248 E L Y + L AA++ I Y GGNT TG AI + + F +S+ K+A+++ Sbjct: 86 VLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRF---LTKIAVVL 142 Query: 249 TDGKSQDEVEIPARELRNVGVEVFSLGI-KAADAKELKQIASTPSLNHVFNVANFDAIVD 307 TDGKSQD+V+ A+ R+ + +F++G+ + EL+ IA+ PS +VF V ++ AI Sbjct: 143 TDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISK 202 Query: 308 IQNEIISQVC--SGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYK 365 I+ + ++C S ++ E + L+ ++V+ K VK SP + GY+ Sbjct: 203 IREVMKQKLCEESVCPTRIPVAARDERGFD---ILLGLDVNKK-VKKRIQLSPKKIKGYE 258 Query: 366 V 366 V Sbjct: 259 V 259 Score = 43.5 bits (101), Expect = 0.003 Identities = 29/80 (36%), Positives = 33/80 (41%), Gaps = 8/80 (10%) Query: 2982 LPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041 +PG GE G S P P G PG G +G PG PG PG G G G P Sbjct: 423 IPGFNGECLNGPSDVGSTPAPC----ICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKP 478 Query: 3042 GYCDSSQCASIPYNGQGYPG 3061 GY + +P G PG Sbjct: 479 GYQGIAGTPGVP----GSPG 494 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 352 bits (902), Expect = 4e-96 Identities = 304/1020 (29%), Positives = 470/1020 (46%), Gaps = 57/1020 (5%) Query: 1192 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFD--IGPKRVQIALAQYSGDPRT 1249 C ADIV L+DGS SIGR+NFR VRSF+ +V F + V+ A QYS DPRT Sbjct: 31 CTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRT 90 Query: 1250 EWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITD 1309 E+ L+A +++A+ L YKGGNT TG A+ + F Q RP K+ +LITD Sbjct: 91 EFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA-RPGVPKVCILITD 149 Query: 1310 GKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVD 1369 GKSQD V+ +++LK +GV+LFA+GIKNAD ELK +A+ P + V DF L ++ Sbjct: 150 GKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLP 209 Query: 1370 DLTINLCNSVKG------PGD-LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPV 1422 ++ +C + G P D AP +LV+SE + +S RV WT S V YKV+Y P+ Sbjct: 210 LVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPL 269 Query: 1423 SG------GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP 1476 +G +RQE V ETS L+ L+P TEY V V ++ + E + GT +T + Sbjct: 270 TGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALE 329 Query: 1477 VVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLV 1536 L I + ++ V W+ V GATGY ++++ V PT+ +E LGP + L DL Sbjct: 330 GPELTIQNTTAHSLLVAWRSVPGATGYRVTWR-VLSGGPTQQQE--LGPGQGSVLLRDLE 386 Query: 1537 PNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY 1596 P T+Y VTV + L + P T Q L+ + +++ + W VP + R Y Sbjct: 387 PGTDYEVTV-STLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVP-EARGY 444 Query: 1597 IV--RYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAV---HDEGESPPVTAQET 1651 + R +T E ++V + T L L T Y +++ + H+ V Sbjct: 445 RLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGP 504 Query: 1652 TRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVF 1711 PV T+L+ TE+ + R +W + YRI ++ +L G + Sbjct: 505 ELPVSPVTDLQATELPGQRVRVSWS-PVPGATQYRIIVRSTQGVER-TLVLPGSQTAFDL 562 Query: 1712 ENLNPNTIYEVSITA-IYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLT 1770 +++ Y V ++A + P E GS L + L+V + + + Sbjct: 563 DDVQAGLSYTVRVSARVGPRE-------GSASVLTVRREPETPLAVPGLRVVVSDATRVR 615 Query: 1771 VKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDG 1830 V W P G +RI++ STG G E + T+ + + L+P T Y + VS L Sbjct: 616 VAWGPVPG-ASGFRISW--STGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672 Query: 1831 EGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVP 1890 EG +T PL VR + V S+S++ + W G Y++ + +A GPE+ Sbjct: 673 EGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRVSW-HSAHGPEKSQL 730 Query: 1891 IPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPN 1948 + G A L L+PDT YTV V DG S RT + R +Q+ N + + Sbjct: 731 VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSD 790 Query: 1949 SLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALY 2008 L + W G YR+ + +G P ++PGNT + L YSV + AL Sbjct: 791 VLRITWVGVTG-ATAYRLAWGRSEG-GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALV 848 Query: 2009 SDGEGNPSPAQGRTLPRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 2066 D EG P T P + P L V +SL + W+ Q + + + P G Sbjct: 849 GDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVP-RAQGFLLHWQPEGGQ- 906 Query: 2067 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVG-LLPPQNIHIS 2125 ++ + ++ L L+P T Y++ + + G+G RT +P + + Sbjct: 907 -EQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVV 965 Query: 2126 DEWYTRFRVSWDPSPSPVLGYKIVYKPV---GSNEP--MEAFVGEMTSYTLHNLNPSTTY 2180 D ++W P S Y + ++P+ G P + G +S + L P +Y Sbjct: 966 DTSIDSVTLAWTP-VSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024 Score = 266 bits (681), Expect = 2e-70 Identities = 234/752 (31%), Positives = 344/752 (45%), Gaps = 46/752 (6%) Query: 439 ADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFE--ISPNRVQISLVQYSRDPHTEFTLKK 496 ADIVFL+DGS SIG +NF +VR+FLE LV F S V+ + VQYS DP TEF L Sbjct: 37 ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96 Query: 497 FTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDA 556 D+I AI Y+GG+T TG A+ +V + +F+P +R VPKV ILITDGKS D Sbjct: 97 LGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL-ARPGVPKVCILITDGKSQDL 155 Query: 557 FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616 A +L+ V++FAVG+K+A EL+ +AS P F V DF + + +++ + Sbjct: 156 VDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRV 215 Query: 617 CLRI-EQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAG---- 671 C + + P+DL SE +S + W+ A V Y + Y G Sbjct: 216 CTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQP 275 Query: 672 --DDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNL 729 + V PA TSV L L+P T Y V V A Y + ++G T ++G L Sbjct: 276 LPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP--EL 333 Query: 730 KVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYE 789 + + T S + W PG YR+ +R ++GG +++ P Q L +L P T YE Sbjct: 334 TIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYE 392 Query: 790 VSVIPEY--FSGPGTPLTG--NAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYL 845 V+V + GP T L +A+ E+ LR +++ LSW+ P + + Y Sbjct: 393 VTVSTLFGRSVGPATSLMARTDASVEQT------LRPVILGPTSILLSWNLVP-EARGYR 445 Query: 846 VTYTPVAGGE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL-- 902 + + G E Q+V + D T L GL+ GT+Y L+ LY G + T + Sbjct: 446 LEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLT---LYTLLEGHEVATPATVVPT 502 Query: 903 --EERGSP-QDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIH 959 E SP DL ++ + W+ PG + YR+ +S T LP Sbjct: 503 GPELPVSPVTDLQATELPGQRVRVSWSPVPGATQ-YRIIVRSTQGVERT--LVLPGSQTA 559 Query: 960 TMIENLQPETKYRISVFATYSSGEGEP--LTGDATTELSQDSKTLKVDEETENTMRVTWK 1017 ++++Q Y + V A EG LT E L+V +RV W Sbjct: 560 FDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWG 619 Query: 1018 PAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077 P PG +R+ + G G + +PP T+T + LQP TTY + V + EG Sbjct: 620 PVPG-ASGFRISWST-GSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAA 677 Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137 T R + + + SS +TW PG GY+V++H + +LV G Sbjct: 678 VIVART-DPLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRVSWHSAHGPEK-SQLVSG- 733 Query: 1138 YDNTVV-LEELRAGTTYKVNVFGMFDGGESSP 1168 + TV L+ L T Y V+V G + P Sbjct: 734 -EATVAELDGLEPDTEYTVHVRAHVAGVDGPP 764 Score = 263 bits (672), Expect = 2e-69 Identities = 262/1054 (24%), Positives = 441/1054 (41%), Gaps = 91/1054 (8%) Query: 1489 TMHVQWQPVGG-ATGYILSYKPVKDTE---PTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 1544 ++ VQW G TGY + Y P+ P+ +EV + ++L L P TEY VT Sbjct: 247 SLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVT 306 Query: 1545 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 1604 V A+ + E V+ T L P+ L +++ T ++ V W VPG + Sbjct: 307 VIALYANSIGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPGATGYRVTWRVLSG 365 Query: 1605 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVT--------AQETTRPVP 1656 ++ E+ + S L+DL T Y V+VS + P + ++T RPV Sbjct: 366 GPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRPVI 425 Query: 1657 -APTNLKITEVTSEGFRGTWDHGASDVSLYRITWA-PFGSSDKMETILNGDENTLVFENL 1714 PT++ ++ RG YR+ W G + +L D + L Sbjct: 426 LGPTSILLSWNLVPEARG-----------YRLEWRRETGLEPPQKVVLPSDVTRYQLDGL 474 Query: 1715 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 1774 P T Y +++ + + + T+ + P S +LQ + V W Sbjct: 475 QPGTEYRLTLYTLLEGHE-----VATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWS 529 Query: 1775 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGR 1834 P G Q YRI + + +G E+T + G Q + L ++ YT+ VS+ EG Sbjct: 530 PVPGATQ-YRIIVRST--QGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586 Query: 1835 --MTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP 1892 +T R + + V LRV + + V W G +++ ++ +G PE +P Sbjct: 587 SVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPG-ASGFRISWSTGSG-PESSQTLP 644 Query: 1893 GNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDV 1952 ++ + LQP T+Y V V + +G RT G R V V + +S+ + Sbjct: 645 PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTI 704 Query: 1953 RWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGE 2012 W PG YRV + G P +S +V G + L+ L PDT Y+V++ A + + Sbjct: 705 TWTRVPGAT-GYRVSWHSAHG--PEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVD 761 Query: 2013 GNPSPAQGRTLPRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEY 2070 G P+ RT P R L++ +++ L + W G YR+ + + G P+ + Sbjct: 762 GPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATA-YRLAWGRSEGGPM-RH 819 Query: 2071 TTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQ--NIHISDEW 2128 +PG ++ ++ L+ Y + V A+ D +G ++ T PP +H+ Sbjct: 820 QILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRG 879 Query: 2129 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDV--NVYA 2186 R+ W+P P G+ + ++P G E E++SY L L P+T Y V +V Sbjct: 880 EHSLRLRWEPVPR-AQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLG 938 Query: 2187 QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ 2246 G S +T + + + +L+ D+ + W+P A+SY L P G GQ Sbjct: 939 PAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGP-GQ 997 Query: 2247 EI-----TVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301 E+ T+ G +S TGL P Y +F TP L+G P Sbjct: 998 EVPGSPQTLPGISSSQRVTGLEPGVSY---IFSLTPVLDG-------------VRGPEAS 1041 Query: 2302 PTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVV---KFIFNTVGGFDEISP 2358 T P VC AD+VFL A+ DN ++ + + V + P Sbjct: 1042 VTQTP---------VCPRGLADVVFLPHAT----QDNAHRAEATRRVLERLVLALGPLGP 1088 Query: 2359 AGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYR--GGNTRTGKALTFIKEKVLT 2416 +QV + YS F LN +D + L ++++ Y GN +T + + Sbjct: 1089 QAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAP 1148 Query: 2417 WESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIA-SKP 2475 G R++VP V+V++ D + ++ Q SG +V ++G+A D +L +A Sbjct: 1149 DAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMD 1208 Query: 2476 SERHVFIVDDFESFEKIEDNLITFVCETATSSCP 2509 S + F VDD S ++ L T +C+ + ++ P Sbjct: 1209 SVQTFFAVDDGPSLDQAVSGLATALCQASFTTQP 1242 Score = 234 bits (597), Expect = 1e-60 Identities = 145/331 (43%), Positives = 162/331 (48%), Gaps = 66/331 (19%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGP---------------PGPRGDIGPPGPQGPP 2791 G PG PGP G PG +GPRG +G GA G PGP G GP GP G P Sbjct: 1326 GSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDP 1385 Query: 2792 GPQGPNGLSIPGEQGRQGMKGDAGEPG------LPGRTGTPGLPGPP---GPMGPPGDRG 2842 GP+GP GL +G +G +G+ G PG PG G PGLPG P GP+GPPG +G Sbjct: 1386 GPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445 Query: 2843 FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIAS 2900 G D G G PG PGSPG G GP G G GD G PGP G GEKG+RG A Sbjct: 1446 EKG-DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAG 1504 Query: 2901 QNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG 2960 + VA +PG GP GPPG G +GE G Sbjct: 1505 SRGLPGVA------------------------------GRPGAKGPEGPPGPTGRQGEKG 1534 Query: 2961 PGGRPGFPGT--PGMQGPPGERGLPGEKGERG-TGSSGPRG-----LPGPPGPQGE-SRT 3011 GRPG P P + GP GE+G G G RG TG G RG LPG PGP+G+ Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR 1594 Query: 3012 GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GP G TG GPPG G PG G G PGPPG Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625 Score = 233 bits (594), Expect = 2e-60 Identities = 158/388 (40%), Positives = 185/388 (47%), Gaps = 95/388 (24%) Query: 2747 GPPGPPGPAGGPGAKGP--------RGERGISGAIGPPGPR------GDIGPPGPQGPPG 2792 GPPGP GP G PG +GP +G++G G GPPGP G+ G PG G PG Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP---PGPMGPPGDRGFTG---K 2846 PQGP G PG++G +G D G PGLPG+ G+PG GP PG +GP GDRGF G + Sbjct: 1434 PQGPVGP--PGKKGEKGDSED-GAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGE 1490 Query: 2847 DGAMGPRGPPGPPGSPGSPGVT------------GPSGKPGKPGDHGRPGP--------S 2886 G G RGPPGP GS G PGV GP+G+ G+ G+ GRPG + Sbjct: 1491 AGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVA 1550 Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLI----------------SGQMNRFNQMLNQI 2930 G KGEKGD G + + L+ G R + Sbjct: 1551 GPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG 1610 Query: 2931 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP------GMQGPPGERGLPG 2984 P + +PGPPGP GP G G GE G G PG PG P G++G PG RG G Sbjct: 1611 PPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVG 1670 Query: 2985 EKGERG----------TGSSGP---RGLPGPPGPQGE--------SRTGPPGSTGSRGPP 3023 EKG++G GSSGP RG PGPPGP G G PG G GP Sbjct: 1671 EKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPR 1730 Query: 3024 GP------PGRPGNSGI---RGPPGPPG 3042 GP PG PG GI RGPPGP G Sbjct: 1731 GPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Score = 231 bits (589), Expect = 8e-60 Identities = 151/347 (43%), Positives = 167/347 (48%), Gaps = 51/347 (14%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQ 2805 G PGP G G PG G RG G G G GPRG GP G G PGP G GL+ P G Q Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200 Query: 2806 GRQGMKGDAGEPGLPGR-----TGTPGLPGPPGP---MGP------PGDRGFTGKDGAMG 2851 G G+KG+ GE G PGR TG GLPGPPGP +GP PG G TGK GA G Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260 Query: 2852 ---------PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP--GPSGLKGEKGDRGDIAS 2900 RG PG PGSPG PG GP G+PG G G+ G G KGEKG G +A Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAG 2320 Query: 2901 QNMMRAVAR-------------QVCEQLISGQMNRFNQMLNQIPNDYQSSR--NQPGPPG 2945 + A+ + G Q P ++ PG PG Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPG 2380 Query: 2946 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004 PPGPPG G G PG G PG G PG GP GE G PG GERG G G G+PGP G Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440 Query: 3005 PQG-ESRTGPPGSTGSRGP--------PGPPGRPGNSGIRGPPGPPG 3042 P G GPPG++G +G PGP G G GIRG G PG Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG 2487 Score = 227 bits (578), Expect = 2e-58 Identities = 154/386 (39%), Positives = 176/386 (45%), Gaps = 86/386 (22%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG------PGAKGPRGERGISGAIGPPGPRGDIGPPG 2786 P P+ G PG PG AGG PG +G RGE+G G G GP G G PG Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085 Query: 2787 PQGPPGP--------------QGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGL 2828 P GPPGP QGP GL PG G QG KGD G PG+ G G PG Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145 Query: 2829 PGPPGPMGPPGDRGFTG---KDGAMGPRGPPGP------PGSPGSPGVT------GPSGK 2873 G G G PG+RG G K G GPRGPPGP PG PG+PG+ GPSG Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205 Query: 2874 PGKPGDHGRPGPS--------GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925 G+PG+ G PG GL G G G + Q + QV E G R Sbjct: 2206 KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG-SPGLPGQVGETGKPGAPGRDG- 2263 Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP-----GFPGTPGMQGPP--- 2977 + R PG PG PG PG G +GEPGP G P G PG G +G P Sbjct: 2264 -----ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL 2318 Query: 2978 -----------GERGLPGEKGERG----------TGSSGPRGLPGPPGPQGESRTGPPGS 3016 G+RGLPG +GE+G G G +G PGP G +G+ G PGS Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS 2378 Query: 3017 TGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GPPGPPG G+ G+ G PG PG Sbjct: 2379 P---GPPGPPGVKGDLGLPGLPGAPG 2401 Score = 225 bits (574), Expect = 5e-58 Identities = 149/372 (40%), Positives = 172/372 (46%), Gaps = 82/372 (22%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---------------QGPP 2791 G PG GP G PGA GP+G+RG G +G G +G+ GPPGP +GP Sbjct: 1462 GSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521 Query: 2792 GPQGPNG-LSIPGEQGR--------------QGMKGDAGEPGLPGRTGTPG--------L 2828 GP GP G GE GR +G KGD G G G TG G L Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL 1581 Query: 2829 PGPPGPMGPPGDR---GFTGKDGAMGPRGPPGPPGSPGSPGVTGP------SGKPGKPGD 2879 PG PGP G PGDR G TG+ G G GPPG G PG PG GP G+ G+ GD Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD 1641 Query: 2880 HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939 G PG GL G+ G+RG + +R + +Q G+ R + P + R Sbjct: 1642 EGPPGDPGLPGKAGERG-LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGP---KGDRG 1697 Query: 2940 QPGPPGPP-------------GPPGSAGARGEPGPGGRPGFPGT------------PGMQ 2974 +PGPPGPP G PG G G GP G PG PG PG Q Sbjct: 1698 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ 1757 Query: 2975 GPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRP---G 3030 G PG RG GEKG+RG G G GL G PG G S GP G+ G G PG G P G Sbjct: 1758 GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS--GPNGAAGKAGDPGRDGLPGLRG 1815 Query: 3031 NSGIRGPPGPPG 3042 G+ GP GPPG Sbjct: 1816 EQGLPGPSGPPG 1827 Score = 224 bits (572), Expect = 8e-58 Identities = 140/341 (41%), Positives = 157/341 (46%), Gaps = 61/341 (17%) Query: 2747 GPPGPPGPAGGPGA---KGPRGERG-------ISGAIGPPGPRGDIGPPGPQGPPG-PQG 2795 GPPG GP G PG KG RG+ G G GPPGP G G PG G PG P Sbjct: 1988 GPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGR 2047 Query: 2796 PNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDR--------GFTGKD 2847 G+ G G +G +G+ GE G GR G PGLPG PGP GPPG + G +G+ Sbjct: 2048 AGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQ 2107 Query: 2848 GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 G G +G G PGS G G G G PG GD G PGP G G G G+ R + Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGE-------RGM 2160 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967 A +PG GP GPPG G G+PGP G PG Sbjct: 2161 A---------------------------GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193 Query: 2968 PGTPGMQGPPGERGLPGEKGERGTGSSGPR---GLPGPPGPQG----ESRTGPPGSTGSR 3020 G G QGP G +G PGE G G G +GP GLPGPPGP G + G PG G Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGET 2253 Query: 3021 GPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG PGR G SG G G PG S P +G PG Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPG-PVGPKGEPG 2293 Score = 223 bits (569), Expect = 2e-57 Identities = 153/391 (39%), Positives = 177/391 (45%), Gaps = 81/391 (20%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRGDIGPPGPQGPPGPQG---PNG 2798 GP GPPGP G G KG G G +GP G +GD+GP GP+G G QG P G Sbjct: 1519 GPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPG 1578 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPG---------PMGPPGDRGFTGKDGA 2849 L +PG+ G +G GD G GL GR G PG GPPG P GP G RG G+ G Sbjct: 1579 LVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE 1638 Query: 2850 MGPRGPPGPPGSP---------GSPGVTGP---SGKPGKPGDHGRPGPSGLKGEKGDRGD 2897 G GPPG PG P G+PGV GP G G PG+ GR G G G KGDRG+ Sbjct: 1639 KGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE 1698 Query: 2898 IASQNMMRAV------ARQVCEQLISGQMN----RFNQMLNQIPND--YQSSRNQPGPPG 2945 + AR+ E GQ + + L P + + R PGP G Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Query: 2946 PP---GPPGSAGARGEPGPGGRPGFPGTPGMQGP------------PGERGLPGEKGERG 2990 P GP G G RG PG GR G G PG GP PG GLPG +GE+G Sbjct: 1759 DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQG 1818 Query: 2991 -TGSSGPRGLPGPPGPQG-------------------ESRTGPPGSTGSRGPPGPPGRPG 3030 G SGP GLPG PG G + G G++G G GP G G Sbjct: 1819 LPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERG 1878 Query: 3031 NSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GI GP GPPG + GQG+PG Sbjct: 1879 APGILGPQGPPGL-----PGPVGPPGQGFPG 1904 Score = 222 bits (565), Expect = 5e-57 Identities = 134/350 (38%), Positives = 164/350 (46%), Gaps = 56/350 (16%) Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 D VG PG G G PG +G +GE G +G G PG G G PGP+G G G PG Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPG 2380 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM------GPPGDRGFT---GKDGAMGPRG 2854 G G+KGD G PGLPG G G PG GP GP G+RG G++G GP G Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440 Query: 2855 PPGPPGS--------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGL 2888 PPGPPGS G PG+ G G+PG+ G G GP G Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGS 2500 Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948 +GE+G++GD+ S + G M + P + GP G G Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDK---GPRGDNG 2557 Query: 2949 PPGSAGARGEP---------------GPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TG 2992 PG G++GEP GP G+PG G PG G PG+ G+PG +GE+G G Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617 Query: 2993 SSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GPRGL G G +G G G G +G GPPGRPG +G +G G PG Sbjct: 2618 FMGPRGLKGERGVKG--ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPG 2665 Score = 221 bits (562), Expect = 1e-56 Identities = 141/354 (39%), Positives = 173/354 (48%), Gaps = 71/354 (20%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP---PGPQGPNGLS-I 2801 +GPPGPPG G PGA G +G++G G +G PGPRG+ G PG +G PG +GP GL+ Sbjct: 2439 LGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP 2497 Query: 2802 PGEQGRQGMKGDAGEPGLPGRTGTPG-LPGPPGPMGPPGD---RGFTGKDGAMGPRGPPG 2857 PG +G +G KGD G GL G G + GPPGP G GD RG G DG GPRG G Sbjct: 2498 PGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNG 2557 Query: 2858 PPGS---------------PGSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIA 2899 PG PG G+ GP G+PG PGD G PG G+ G +G++GD+ Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617 Query: 2900 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 2959 E+ + G + + + + GPPG PG G G GEP Sbjct: 2618 FMGPRGLKG----ERGVKGACGLDGE---------KGDKGEAGPPGRPGLAGHKGEMGEP 2664 Query: 2960 GPGGRPGFPGTPGMQGPPGERGLPG---------EKGERGT-------------GSSGPR 2997 G G+ G PG G+ GP G+RG G EKGERGT GS+GP Sbjct: 2665 GVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPP 2724 Query: 2998 GLPGPPGPQG-------ESRTGPPGS--TGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G PG GP+G + GPPG G+ G PG PG G G GP GP G Sbjct: 2725 GPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778 Score = 218 bits (555), Expect = 7e-56 Identities = 139/317 (43%), Positives = 153/317 (48%), Gaps = 52/317 (16%) Query: 2748 PPGPPGPAGGP-GAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805 P P P P G KG GE G+ G +GPPG D G PG G PGPQGP G + GE+ Sbjct: 1242 PRPEPCPVYCPKGQKGEPGEMGLRGQVGPPG---DPGLPGRTGAPGPQGPPGSATAKGER 1298 Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGS---- 2861 G G G G PG G GTPG PG G G PG RG G+ G GP+G PG PG Sbjct: 1299 GFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGG 1358 Query: 2862 -----PGSPGVTGPSGKPGKPGDHGRPGPSG--------LKGEKGDRGDIASQNMMRAVA 2908 PG G GPSG PG G G PGP G +KG+KGDRG+ Sbjct: 1359 EGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPG---- 1414 Query: 2909 RQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARG--EPGPGGRPG 2966 G + L +P PGP GP GPPG G +G E G G PG Sbjct: 1415 --------EGGIAPGEPGLPGLP-------GSPGPQGPVGPPGKKGEKGDSEDGAPGLPG 1459 Query: 2967 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGP 3025 PG+PG QGP G G G KG+ RG PGP G GE GPPG GSRG PG Sbjct: 1460 QPGSPGEQGPRGPPGAIGPKGD--------RGFPGPLGEAGEKGERGPPGPAGSRGLPGV 1511 Query: 3026 PGRPGNSGIRGPPGPPG 3042 GRPG G GPPGP G Sbjct: 1512 AGRPGAKGPEGPPGPTG 1528 Score = 218 bits (555), Expect = 7e-56 Identities = 136/362 (37%), Positives = 168/362 (46%), Gaps = 74/362 (20%) Query: 2735 FPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ 2794 FP T + +G PGP +G G GP G GI G +GPPGP G +GPPG G G + Sbjct: 2405 FPGQ-TGPRGEMGQPGP---SGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460 Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP-------------------- 2834 G G+ +PG +G +G G GE G PG+ G GL GPPG Sbjct: 2461 GDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520 Query: 2835 -----MGPP---------GDRGFTGKDGAMGPRGPPGPPGS---------------PGSP 2865 +GPP G+RG G DG GPRG G PG PG Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580 Query: 2866 GVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNR 2922 G+ GP G+PG PGD G PG G+ G +G++GD+ E+ + G Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG----ERGVKGACGL 2636 Query: 2923 FNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGL 2982 + + + + GPPG PG G G GEPG G+ G PG G+ GP G+RG Sbjct: 2637 DGE---------KGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGF 2687 Query: 2983 PGEKGERG-TGSSGPRGLPGP---PGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037 G+ G +G G G RG PG PGP G + GPPG GS GP GP G G G RGP Sbjct: 2688 DGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGP 2747 Query: 3038 PG 3039 PG Sbjct: 2748 PG 2749 Score = 217 bits (553), Expect = 1e-55 Identities = 153/423 (36%), Positives = 180/423 (42%), Gaps = 127/423 (30%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP------QGPPG-------- 2792 G GP GP G PG G GERGI G GPPGP+GD G GP +GPPG Sbjct: 1725 GQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784 Query: 2793 -------PQGPNGLS----------IPGEQGRQGMKGDAGEPGLPGR------------T 2823 P GPNG + +PG +G QG+ G +G PGLPG+ Sbjct: 1785 GKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKN 1844 Query: 2824 GTPGLPGPPGPMGPPGDRGFTGKDGAMGPR---------GPPGPPGSPGS--------PG 2866 G PG PG G G GD G +G++G GP+ GP GPPG PG PG Sbjct: 1845 GEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPG 1904 Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGD----------IASQNMMRAVARQVCE--Q 2914 V G +G G G+ G G GL GE+G RG+ + + + + R++ E Sbjct: 1905 VPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWD 1964 Query: 2915 LISGQMNRFNQMLNQIPND--------------------YQSSRNQPGPPGPP------- 2947 SG + D + R PGP GPP Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGER 2024 Query: 2948 GPPGSAGARGEPGPGGRPGFPGTP---GMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP 3003 GPPG +G GEPG G PG PG G G PGERG GEKGERG G GP GLPG P Sbjct: 2025 GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTP 2084 Query: 3004 GPQG------------------------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPG 3039 GP G + G PGS G +GP G G PG G RG PG Sbjct: 2085 GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPG 2144 Query: 3040 PPG 3042 P G Sbjct: 2145 PRG 2147 Score = 217 bits (552), Expect = 2e-55 Identities = 148/378 (39%), Positives = 169/378 (44%), Gaps = 100/378 (26%) Query: 2747 GPPGPPGPAG-----GPGAKGPRGERGISGAIGPPGPRGDIGPPGP---------QGPPG 2792 G PGPPGP G GPGA+ +GE G G GP GP+GD G PG +GPPG Sbjct: 1697 GEPGPPGPPGRLVDTGPGAR-EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG 1755 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGK 2846 PQG PG +G G KGD G PGL GR+G G PG GP GP GD G G Sbjct: 1756 PQGD-----PGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL 1810 Query: 2847 DGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRA 2906 G G +G PGP G PG PG G GKPG G +G PG G G KG++GD + Sbjct: 1811 PGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGA------ 1864 Query: 2907 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPG 2966 SG+ R + + R PG GP GPPG G G PG G Sbjct: 1865 ----------SGREGR---------DGPKGERGAPGILGPQGPPGLPGPVGPPGQG---- 1901 Query: 2967 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPG---------------------- 3004 FPG PG GP G+RG G KGE+G G RGL G PG Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGEQGL--PGERGLRGEPGSVPNVDRLLETAGIKASALREI 1959 Query: 3005 ------------PQGESRTGPPGSTGSRGPPG---PPGRPGNSGIRG------PPGPPGY 3043 P E R GP G +G +GPPG P G PG G++G P GPPG Sbjct: 1960 VETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL 2019 Query: 3044 CDSSQCASIPYNGQGYPG 3061 + P G PG Sbjct: 2020 ALGERGPPGPSGLAGEPG 2037 Score = 215 bits (548), Expect = 5e-55 Identities = 145/341 (42%), Positives = 161/341 (47%), Gaps = 68/341 (19%) Query: 2746 VGPPGPPGPAGGPGAK-----GPRGERGISGA-----IGPPGPRGDIGPPGPQGPPGPQG 2795 VGP G PGP G PG G +GE+G G +G PG +GD G PGP+G G G Sbjct: 2286 VGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG 2345 Query: 2796 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA----- 2849 G PGE G++G G G G PG G PG PGPPGP G GD G G GA Sbjct: 2346 RAGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVG 2404 Query: 2850 ----MGPRGPPGPPGS---------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 2896 GPRG G PG PG G+ GP G PG PG G PG SGLKG+KGD G Sbjct: 2405 FPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG 2464 Query: 2897 -DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGA 2955 + R E I G+ R Q GP G GPPGS G Sbjct: 2465 VGLPGPRGERG------EPGIRGEDGR---------------PGQEGPRGLTGPPGSRGE 2503 Query: 2956 RGEPGPGGRPGFPGTPG----MQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG 3007 RGE G G G G G + GPPG RG G+ GERG G GPRG G PG +G Sbjct: 2504 RGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563 Query: 3008 ESRTGPPGSTGSRGPP------GPPGRPGNSGIRGPPGPPG 3042 G PG GS G P GP G+PG +GI G PG PG Sbjct: 2564 SK--GEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602 Score = 213 bits (541), Expect = 3e-54 Identities = 133/323 (41%), Positives = 150/323 (46%), Gaps = 50/323 (15%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQ 2805 VG G GP G PG G GERG+ GA PG RG +G G QG PG G NG PG Sbjct: 1636 VGEKGDEGPPGDPGLPGKAGERGLRGA---PGVRGPVGEKGDQGDPGEDGRNG--SPGSS 1690 Query: 2806 GRQGMKGDAGEPGLPGR----------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP 2855 G +G +G+ G PG PGR G PG G GP GP GD G G G G G Sbjct: 1691 GPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGF 1750 Query: 2856 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915 GPPG G PGV GP+G+ G G G G SGL G+ G G + N A Sbjct: 1751 RGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGP-SGPNGAAGKAGDPGRDG 1809 Query: 2916 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG 2975 + G + + PGP GPPG PG G G+PG G+ G PG PG G Sbjct: 1810 LPG---------------LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDG 1854 Query: 2976 PPGER---------GLPGEKGERGT----GSSGPRGLPGPPGPQGE------SRTGPPGS 3016 GE+ G G KGERG G GP GLPGP GP G+ TGP G Sbjct: 1855 RKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGD 1914 Query: 3017 TGSRGPPGPPGRPGNSGIRGPPG 3039 G G G G PG G+RG PG Sbjct: 1915 RGETGSKGEQGLPGERGLRGEPG 1937 Score = 212 bits (540), Expect = 4e-54 Identities = 125/321 (38%), Positives = 147/321 (45%), Gaps = 46/321 (14%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G G PGP+G G GP G GI G +GPPGP G +GPPG G G +G G+ +PG +G Sbjct: 2413 GEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG 2472 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG-------PPGPP 2859 +G G GE G PG+ G GL GPPG G G++G G G G +G PPGP Sbjct: 2473 ERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR 2532 Query: 2860 GSPGSPGVTGP---SGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLI 2916 G+ G G GP G G GD+G PG G KGE GD+G + + Sbjct: 2533 GAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLG-------- 2584 Query: 2917 SGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP 2976 P + PG PG PG G G RGE G G G G G +G Sbjct: 2585 --------------PQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGV 2630 Query: 2977 PGERGLPGEKGERG----------TGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGP 3022 G GL GEKG++G G G G PG PG G E GP G G G Sbjct: 2631 KGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ 2690 Query: 3023 PGPPGRPGNSGIRGPPGPPGY 3043 PGP G G G RG PG G+ Sbjct: 2691 PGPKGDQGEKGERGTPGIGGF 2711 Score = 207 bits (527), Expect = 1e-52 Identities = 133/326 (40%), Positives = 151/326 (46%), Gaps = 65/326 (19%) Query: 2752 PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMK 2811 P P G KG GE+G G GP G G+ G G +G PGPQGP GL++ GE+G G Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLAL-GERGPPGPS 2030 Query: 2812 GDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPS 2871 G AGEPG PG G PG G G G PG+RG G+ G G +G GPPG PG+PG GP Sbjct: 2031 GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPP 2090 Query: 2872 G------KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925 G +PG PG G GP GLKG KG+ G Sbjct: 2091 GPKVSVDEPG-PGLSGEQGPPGLKGAKGEPG----------------------------- 2120 Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 2985 S GP G G PG G RGEPGP G+ G PG PG +G G G PG Sbjct: 2121 -----------SNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGL 2169 Query: 2986 KGERGT-GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNS--------GIR 3035 +G RG G G G PGPPG G GP G +G +G PG G PG G+ Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP 2229 Query: 3036 GPPGPPGYCDSSQCASIPYNGQGYPG 3061 GPPGP G P G PG Sbjct: 2230 GPPGPSGLVG-------PQGSPGLPG 2248 Score = 196 bits (498), Expect = 3e-49 Identities = 142/413 (34%), Positives = 167/413 (40%), Gaps = 103/413 (24%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI---SGAIGPPGPRGDIGPPGPQG 2789 P+ PN G G PG G G GP G G+ G G PG G G PG G Sbjct: 1792 PSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPG 1851 Query: 2790 PPGPQGPNGLS-IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP-----------PGPMGP 2837 G +G G S G +GR G KG+ G PG+ G G PGLPGP PG GP Sbjct: 1852 EDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGP 1911 Query: 2838 PGDRGFTGKDGAMGPRGPPGPPGSPGS--------------------------------- 2864 GDRG TG G G G G G PGS Sbjct: 1912 KGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFL 1971 Query: 2865 ---------PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM---------RA 2906 G +G G PGK G G PG GLKG++GD G + Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSG 2031 Query: 2907 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ------------------PGPPGPPG 2948 +A + + I G R + + R + PGPPGPPG Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091 Query: 2949 P--------PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG---------- 2990 P PG +G +G PG G G PG+ G QGP G+RG+PG KG+RG Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151 Query: 2991 TGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G G RG+ GP G G + GPPG G G PGPPG PG +G GP GP G Sbjct: 2152 PGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSG 2204 Score = 190 bits (482), Expect = 2e-47 Identities = 124/304 (40%), Positives = 144/304 (47%), Gaps = 56/304 (18%) Query: 2762 GPRGERGISGAIGPPGPRGDIGPPGPQGPPG--PQGPNGLSIPGEQGRQGMKGDAGEPGL 2819 GP ++ +SG P P+ P P+G G PGE G +G G G+PGL Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGE--PGEMGLRGQVGPPGDPGL 1276 Query: 2820 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD 2879 PGRTG PG GPPG G+RGF G DG G G G PG+PG+PG+ G G PG GD Sbjct: 1277 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD 1336 Query: 2880 HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939 G GP G KGE G G + I + Sbjct: 1337 PGERGPRGPKGEPGAPGQV-------------------------------IGGEGPGLPG 1365 Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP--------GMQGPPG--ERGL-PGEKGE 2988 + G PGP GPPG G G+PGP G PG PGT G +GPPG E G+ PGE G Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425 Query: 2989 RGT-GSSGPRGLPGPPGPQGE---SRTGPPGSTGS------RGPPGPPGRPGNSGIRGPP 3038 G GS GP+G GPPG +GE S G PG G +GP GPPG G G RG P Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485 Query: 3039 GPPG 3042 GP G Sbjct: 1486 GPLG 1489 Score = 179 bits (455), Expect = 3e-44 Identities = 110/301 (36%), Positives = 169/301 (56%), Gaps = 23/301 (7%) Query: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFD--IGEEKTRVGVVQYSSDTRTEFNLNQY 197 D+VFL+DGS S+GR+NF+ + F+ LV F + R VQYS D RTEF L+ Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97 Query: 198 YQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEV 257 +++ AI+++ YKGGNT TG AI ++ + F AR G PKV I+ITDGKSQD V Sbjct: 98 GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL-ARPGVPKVCILITDGKSQDLV 156 Query: 258 EIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVC 317 + A+ L+ GV++F++GIK AD +ELK++AS P+ + F V +F + + + +VC Sbjct: 157 DTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVC 216 Query: 318 SGVDEQLGELVSGEEVVEPPS-------NLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370 + G V PP +L+ E SS+ +++ W + PVTGYKV TP Sbjct: 217 T--------TAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTP 268 Query: 371 MTA-----GSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425 +T S + ++V T++ +R L TEYQ++V A+ + E +S +T + Sbjct: 269 LTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTAL 328 Query: 426 K 426 + Sbjct: 329 E 329 Score = 178 bits (451), Expect = 8e-44 Identities = 122/319 (38%), Positives = 144/319 (45%), Gaps = 31/319 (9%) Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 2799 DS GPPGP G G G RG RG+ G GP G GD G G +G PG +G GL Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK---------DGAM 2850 + G QG+ G G G+PG PG+ G PG+ G G +G G RG G+ DG Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEK 2640 Query: 2851 GPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQ 2910 G +G GPPG PG G G G+PG PG G PG GL G KGDRG Q + + Sbjct: 2641 GDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRG-FDGQPGPKGDQGE 2699 Query: 2911 VCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPG---PPGPPGSAGARGEPGPGGR--- 2964 E+ G + F P+ S PGPPG P GP G G +GE GP G Sbjct: 2700 KGERGTPG-IGGFPG-----PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVV 2753 Query: 2965 -----PGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019 PG PG G QG PG G GEKGE RG Q + G ++GS Sbjct: 2754 GAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGS 2813 Query: 3020 RGPPGPPGRPGNSGIRGPP 3038 R P S + P Sbjct: 2814 RPLPSYAADTAGSQLHAVP 2832 Score = 169 bits (429), Expect = 3e-41 Identities = 187/765 (24%), Positives = 314/765 (41%), Gaps = 58/765 (7%) Query: 634 PPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKP 693 P DL +E+ + +WSP Y I + G + T+V P S T+ L ++ Sbjct: 510 PVTDLQATELPGQRVRVSWSPV-PGATQYRIIVRSTQGVER-TLVLPGSQTAFDLDDVQA 567 Query: 694 ETLYLVNVTAEY--EDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVL 751 Y V V+A +G + L E P L+V ++ W PG Sbjct: 568 GLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATRVRVAWGPVPG-AS 625 Query: 752 RYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEV--SVIPEYFSGPGTPLTGNAA 809 +RI + +G ES + T PP+ + L P T Y+V SV+ GP + A Sbjct: 626 GFRISWSTGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIV---A 681 Query: 810 TEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTV 869 + G R + V+ ++S++ ++W+ PG Y V++ G E ++ V G+ T Sbjct: 682 RTDPLGPVRTVHVTQASSSSVTITWTRVPGATG-YRVSWHSAHGPEKSQL-VSGEATVAE 739 Query: 870 LQGLKEGTQYALSVTALYASGAGD-ALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928 L GL+ T+Y + V A A G A T E G L + + + W Sbjct: 740 LDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGV 799 Query: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988 G YR++W + + LP + I L+ Y + V A EG P++ Sbjct: 800 TGAT-AYRLAW-GRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVS 857 Query: 989 GDATT--ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046 TT E TL V + E+++R+ W+P P + + + ++P G G++ + P Sbjct: 858 IVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVP-RAQGFLLHWQPEG-GQEQSRVLGPE 915 Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPR----NLKTSDPTMSS 1102 ++S L L+P T Y + + + GEG S +R +SPR L+ D ++ S Sbjct: 916 LSSYHLDGLEPATQYRVRLSVLGPAGEGP----SAEVTARTESPRVPSIELRVVDTSIDS 971 Query: 1103 FRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP------YDNTVVLEELRAGTTYKVN 1156 + W P Y +++ P R G+ V G ++ + L G +Y + Sbjct: 972 VTLAWTPV-SRASSYILSWRPL---RGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFS 1027 Query: 1157 VFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFR 1216 + + DG V +++ T V P R AD+V L + Sbjct: 1028 LTPVLDG------VRGPEASVTQTPVCP----------RGLADVVFLPHATQDNAHRAEA 1071 Query: 1217 TVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPY--KGG 1274 T R ++ + +GP+ VQ+ L YS P + LN D +LQ + ++PY G Sbjct: 1072 TRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSG 1131 Query: 1275 NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIG 1334 N L + R G R + VL+ D + D+ +P ++ + G+ + +G Sbjct: 1132 NNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLG 1191 Query: 1335 IKNADEVELKMIATDPDDTHA-YNVADFESLSRIVDDLTINLCNS 1378 + AD +L+ +A D + V D SL + V L LC + Sbjct: 1192 MAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALCQA 1236 Score = 120 bits (300), Expect = 3e-26 Identities = 70/184 (38%), Positives = 104/184 (56%), Gaps = 2/184 (1%) Query: 2322 ADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPA-GIQVSFVQYSDEVKSEFKLNT 2380 ADIVFL D S SIG NF +V F+ V F + A G++ + VQYSD+ ++EF L+ Sbjct: 37 ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96 Query: 2381 YNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDE 2440 + A++ + Y+GGNTRTG A+ + + V + R VPKV +++TDG+SQD Sbjct: 97 LGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA-RPGVPKVCILITDGKSQDL 155 Query: 2441 VKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFV 2500 V AA ++ G +F VG+ + D EL +AS+P+ F V+DF + + V Sbjct: 156 VDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRV 215 Query: 2501 CETA 2504 C TA Sbjct: 216 CTTA 219 Score = 108 bits (269), Expect = 1e-22 Identities = 73/200 (36%), Positives = 83/200 (41%), Gaps = 51/200 (25%) Query: 2878 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSS 2937 G G PG GL+G+ G GD +P Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPG------------------------------LPG----- 1278 Query: 2938 RNQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPGTPGMQGPPGERGLPGEKGE 2988 + G PGP GPPGSA A+GE PG GR G PGTPG G G GLPG +G+ Sbjct: 1279 --RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD 1336 Query: 2989 RGT-GSSGPRGLPGPPGP----QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043 G G GP+G PG PG +G G G G GPPGP G G+ G RGPPG PG Sbjct: 1337 PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396 Query: 3044 CDSSQCASIPYNGQGYPGSG 3063 G PG G Sbjct: 1397 AMKGDKGDRGERGPPGPGEG 1416 Score = 77.4 bits (189), Expect = 2e-13 Identities = 44/105 (41%), Positives = 51/105 (48%), Gaps = 12/105 (11%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802 Q G G PG G PG G G+ GPPGP G +GP GP+G G +G G P Sbjct: 2697 QGEKGERGTPGIGGFPGPSGN------DGSAGPPGPPGSVGPRGPEGLQGQKGERG--PP 2748 Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 2847 GE+ + G G PG PG G G PGP GP G G+ T D Sbjct: 2749 GER----VVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDD 2789 Score = 67.4 bits (163), Expect = 2e-10 Identities = 50/179 (27%), Positives = 73/179 (40%), Gaps = 7/179 (3%) Query: 2119 PQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPV-GSNEPMEAFVGEM------TSYTL 2171 P+++ +S+ RV W + PV GYK+ Y P+ G +P+ + E+ TS L Sbjct: 235 PRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRL 294 Query: 2172 HNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAAT 2231 L P T Y V V A Y + + ++ T L +L + V W AT Sbjct: 295 RGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGAT 354 Query: 2232 SYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHT 2290 YR+ G Q+ + + S L P TDY VTV GP S+ T Sbjct: 355 GYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMART 413 Score = 53.9 bits (128), Expect = 2e-06 Identities = 68/291 (23%), Positives = 112/291 (38%), Gaps = 23/291 (7%) Query: 336 PPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT-----TTLS 390 P L ++ S V L W P S + Y + P+ ++ + PQT ++ Sbjct: 958 PSIELRVVDTSIDSVTLAWTPV-SRASSYILSWRPLRGPGQE--VPGSPQTLPGISSSQR 1014 Query: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450 V L Y S++ + S+ + C RG+ AD+VFL + Sbjct: 1015 VTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPV-------CPRGL---ADVVFLPHATQD 1064 Query: 451 IGIANFVKVRAFLEVLVKSF-EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINT 509 R LE LV + + P VQ+ L+ YS P F L + I++ I Sbjct: 1065 -NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRD 1123 Query: 510 FPYRGGS-TNTGKAMTYVREKIFVP-SKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNS 567 PY S N G A+ + P + G R +VP VM+L+ D P + + S Sbjct: 1124 MPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQAS 1183 Query: 568 DVEIFAVGVKDAVRSELEAIASPPAETHV-FTVEDFDAFQRISFELTQSIC 617 + + +G+ A +L +A F V+D + + L ++C Sbjct: 1184 GLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALC 1234 Score = 48.1 bits (113), Expect = 1e-04 Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 9/151 (5%) Query: 172 IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYK--GGNTMTGDAIDYLVKN 229 +G + +VG++ YS F LN + +L I+ +PY GN + + Sbjct: 1086 LGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYM 1145 Query: 230 TFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIAS 289 ++ G R P V +++ D + ++ P RE + G+ V LG+ AD ++L+++A Sbjct: 1146 LAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA- 1204 Query: 290 TPSLNHVFNVANFDAIVDIQNEIISQVCSGV 320 P ++ +V F A+ D + Q SG+ Sbjct: 1205 -PGMD---SVQTFFAVDD--GPSLDQAVSGL 1229 Score = 41.6 bits (96), Expect = 0.012 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 6/102 (5%) Query: 324 LGELVSGEE---VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHAL 380 +GE VSG +E P L ++ + + W P TGY+V ++ G Q Sbjct: 315 IGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQ- 371 Query: 381 SVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 +GP ++ +RDL T+Y+++VS + G + S+M +T Sbjct: 372 ELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMART 413 Score = 37.4 bits (85), Expect = 0.23 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 4/109 (3%) Query: 318 SGVDEQLGELV--SGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGS 375 +GVD +V + E V S L + SS +++ W + T Y++ G Sbjct: 758 AGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITW-VGVTGATAYRLAWGRSEGGP 816 Query: 376 RQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424 +H + G T + +R L Y + V+A+ G P+SI+ T P Sbjct: 817 MRHQILPG-NTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPP 864 Score = 37.0 bits (84), Expect = 0.30 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 350 VKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKG 409 V++ W P P +G+++ + T + + ++ P +T + L T YQ++VS ++G Sbjct: 614 VRVAWGPVPG-ASGFRISWS--TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670 Query: 410 MTSSEPISIMEKTQPM 425 I+ +T P+ Sbjct: 671 REEGPAAVIVARTDPL 686 Score = 36.6 bits (83), Expect = 0.39 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 3/91 (3%) Query: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393 V P ++L A E+ + V+++W+P P T Y++I+ T G + + G Q T + D Sbjct: 508 VSPVTDLQATELPGQRVRVSWSPVPG-ATQYRIIVR-STQGVERTLVLPGSQ-TAFDLDD 564 Query: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQP 424 + A Y + VSA G + + +P Sbjct: 565 VQAGLSYTVRVSARVGPREGSASVLTVRREP 595 Score = 36.2 bits (82), Expect = 0.51 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 36 IDENTVH---MSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVV 92 I T H ++W + V GYR+T + GPT++ L LL +L P T+Y V Sbjct: 335 IQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEV 393 Query: 93 TITS 96 T+++ Sbjct: 394 TVST 397 Score = 36.2 bits (82), Expect = 0.51 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 3/101 (2%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 +V+ + + P + + SS V + W P TGY+V + +A + + V + Sbjct: 679 IVARTDPLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRV--SWHSAHGPEKSQLVSGEA 735 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKV 427 T + L DTEY + V A P S++ +T P V Sbjct: 736 TVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPV 776 Score = 33.9 bits (76), Expect = 2.5 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 6/73 (8%) Query: 28 PSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT------DGPTKEFTLSASTTETLL 81 P DL ++ + W P+ GY++ P T +E + A T L Sbjct: 235 PRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRL 294 Query: 82 SELVPETEYVVTI 94 L P TEY VT+ Sbjct: 295 RGLRPLTEYQVTV 307 >gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] Length = 2296 Score = 342 bits (877), Expect = 3e-93 Identities = 370/1525 (24%), Positives = 602/1525 (39%), Gaps = 154/1525 (10%) Query: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876 + W+ P + +Y++ + P G +E T+ G + ++GLK G Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687 Query: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931 T++ + T+ + + GE T + + VT +IT +S W SA Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746 Query: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991 V G+RV ++ + + +LP A I +L P KY ++V+ GE + + Sbjct: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806 Query: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051 T VD+ + ++ V W + YR+VY P G +P T S Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866 Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106 L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T + Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166 W P V GY+V P G+ + + + L G TY VF + G ES Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225 PL Q+ T L T + ++ E D +LV W+ RA R + Sbjct: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035 Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270 +++GP + L P +E+ ++ K + LQ +++P Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093 Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330 Y T T + + + + G+RP EAP + D G Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136 Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390 + + P + Y + + R + + N V P L P+N Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179 Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446 L + VSW + + Y++ P +G G E V ++S +L P Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239 Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504 EY V+VY+V +D+ S P+ T P L ++GP TM V W P T ++ Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299 Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564 + Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V S P+ R+ T Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356 Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621 L P + D+T ++ V W + Y +R+ PE +E V S S +L Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415 Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681 +L T Y VS+ A++ ESP + Q++T P +L++ T +WD A Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474 Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 V YRIT+ G +S E + G ++T L P Y +++ A+ + D S Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530 Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799 + + I T+ K P +QV + NS++VKW P+S V YR+T P G G +T Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588 Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859 T G Q + ++ L+P Y ++V + P GE + T + +L+ + ++ Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTS 1647 Query: 1860 LNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 1918 L+ +W Y++ P GP + + + +++ ++ L T Y V+V + Sbjct: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707 Query: 1919 EGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 1977 TL R +V + T ++ + W + ++V P +G P Sbjct: 1708 TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI 1767 Query: 1978 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 2037 + + P + R + L P T Y + L L + +P T P NLR T Sbjct: 1768 QRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATT 1825 Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV---ILQPLQPDTPYKIT 2094 NSL V+W + Y I Y P + VP R V + L+P T Y I Sbjct: 1826 PNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVTEATITGLEPGTEYTIY 1882 Query: 2095 VIAVYEDGDGGHLTGNGRTVGL-----LPPQNIH---ISDEWYTRFRVSWDPSPSPVLGY 2146 VIA+ + L G +T L LP N+H I D T + + P G Sbjct: 1883 VIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGN 1942 Query: 2147 KIVYKPVGSNEPMEAFVGEMTSYTLHNL---NPSTT----------YDVNVYAQYDSGLS 2193 I +P VG+ + H P TT Y NV + G Sbjct: 1943 GIQLPGTSGQQPS---VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIG-H 1998 Query: 2194 VPLTDQGTTLYLNVTDL----KTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEIT 2249 +P D LY + L T Q + W+P + + Y + P GT + + Sbjct: 1999 IPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQ 2057 Query: 2250 VR--GSETSHCFTGLSPDTDYGVTV 2272 R G+ TS TGL+ Y + V Sbjct: 2058 FRVPGTSTSATLTGLTRGATYNIIV 2082 Score = 288 bits (737), Expect = 6e-77 Identities = 295/1234 (23%), Positives = 501/1234 (40%), Gaps = 84/1234 (6%) Query: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697 S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y Sbjct: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786 Query: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756 +VNV EDG S+ L+ +TT AP + V S + W++ + YRI+ Sbjct: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844 Query: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810 Y P G S E+ P TL +L P +Y +++ + TP+ TG + Sbjct: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868 + V +PRDL+ + T + + W+ V Y V PV G Q + + +T Sbjct: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963 Query: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928 V GL G Y V A+ L + TT + +P +L + TD+++ WT Sbjct: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020 Query: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988 + GYR++ L + N+ + NLQP ++Y +S+ A + E T Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079 Query: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048 G TT S E TE T+ +TW PAP + +++ RP +G + +V Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136 Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107 S V+ L P Y T+ + + G+ + + P NL ++P V+W Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195 Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165 E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255 Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225 S P+ + + T + + G + + A SI NF S + Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308 Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280 +V ++ A+ + P TE+ ++ S+ + + P +G ++ TG+ Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364 Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340 + I +F T + PRA G I ++ + + E Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423 Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400 + ++A + + + ++S + P +L + T S Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463 Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458 +SW P+ +V Y++ Y G QEF V +++ + LKP +Y + VY+V Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523 Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514 S+P+ +T + + DV ++ V+W P TGY ++ P Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583 Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574 PT+ K GP +M + L P EY V+V A S+P+ VT +P P DLK Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKF 1640 Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSLKDLFSQTLYT 1631 VT ++++ W P ++ Y VR TP+E +KE+ + +S + L T Y Sbjct: 1641 TQVTPTSLSAQWTPPNVQLTGYRVRV-TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699 Query: 1632 VSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWA 1690 VSV A+ D S P TT V P ++T+ T +W ++ +++ Sbjct: 1700 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1759 Query: 1691 PFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQ 1750 P ++ + D + L P T Y++ + + + S +I + + Sbjct: 1760 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI------ 1813 Query: 1751 APKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVL 1810 P NL+ T NSL V W P R+ Y I Y+ E + Sbjct: 1814 ---DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870 Query: 1811 QKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844 L+P T YTI V +L + + + GR KT L Sbjct: 1871 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904 Score = 281 bits (719), Expect = 7e-75 Identities = 240/929 (25%), Positives = 404/929 (43%), Gaps = 39/929 (4%) Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030 +G P+++ + + +E L P Y V++ A GE P Q P + Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637 Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 2089 L+ T SLS W + + YR+ +P P+ E P ++V++ L T Sbjct: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696 Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 2148 Y+++V A+ + G T+ + PP+ ++D T +SW + G+++ Sbjct: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756 Query: 2149 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207 P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T Sbjct: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816 Query: 2208 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 2265 ++L+ ++ V W P RA T Y +K P R R T TGL P Sbjct: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876 Query: 2266 TDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294 T+Y + V N + + ++ T P Sbjct: 1877 TEYTIYVIALKNNQKSEPLIGRKKTDELP 1905 Score = 262 bits (670), Expect = 3e-69 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%) Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 2258 T TDLK Q+ + +W+P T YR++++P + T +EI + +S Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688 Query: 2259 FTGLSPDTDYGVTVF 2273 +GL T Y V+V+ Sbjct: 1689 VSGLMVATKYEVSVY 1703 Score = 213 bits (543), Expect = 2e-54 Identities = 155/567 (27%), Positives = 252/567 (44%), Gaps = 17/567 (2%) Query: 631 AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688 A PP DL F+ + + W+P ++ ++ + Y +++V + + S +VVL Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325 Query: 689 SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748 ++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383 Query: 749 RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807 + YRI + P G RE P ++ TL NL P T+Y VS++ L G Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443 Query: 808 AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866 +T V PRDL V T +++ +SW V+ Y +TY G QE TV G + Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501 Query: 867 NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922 + GLK G Y ++V A+ +G GD+ E P + D+ D SI Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559 Query: 923 AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982 W + V GYRV+ T K D IE LQP +Y +SV+A SG Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619 Query: 983 EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGR-GKQMVA 1041 E +PL A T + + LK + T ++ W P ++ YRV P + G Sbjct: 1620 ESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678 Query: 1042 KVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101 + P +S V+ L T Y+++V + + QG TT PR + +D T + Sbjct: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738 Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161 + ++W + G++V P + + + P + + L+ GT YK+ ++ + Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797 Query: 1162 DGGESSPLVGQEMTTLSDTTVMPILSS 1188 D SSP+V T + + + L++ Sbjct: 1798 DNARSSPVVIDASTAIDAPSNLRFLAT 1824 Score = 200 bits (508), Expect = 2e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 192 bits (487), Expect = 6e-48 Identities = 294/1314 (22%), Positives = 508/1314 (38%), Gaps = 144/1314 (10%) Query: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390 + V P +L +EV+ V + W P S VTGY+V + P+ G L + + T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963 Query: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450 V LS Y V A+ S+P++ + T+ +D ++ F V+ + S Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 + + RA +I+ R+ + L T + + ++ +++ + Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570 P R N A Y + + KG++ + PK + T + + ++ + + Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104 Query: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625 I +G K VR A + ++ + + T + ++ A Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164 Query: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678 I K P P +L G T +W ++ Y IT G + + V Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 A +S +L P Y V+V +D S+P++ +T P +L+ T+ D+ Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282 Query: 739 FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796 ++TW P + + + Y PV E E++ P+ L NL+P T+Y VSV Y Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342 Query: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855 TPL G T +P + SD T ++ + W + Y + + P G Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400 Query: 856 TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915 +E V + L L GT+Y +S+ AL L G+ +T+ + P+DL Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458 Query: 916 ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975 T TS+ W + VR YR+++ + E +P I L+P Y I+V Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 976 FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031 +A G+ +P++ + TE+ + S+ ++V + +N++ V W P+ V YRV Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089 P +G G P T ++ LQP Y ++V GE + L Q + TT + Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA 1634 Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149 P +LK + T +S W P ++ GY+V P + E+ + P ++VV+ L Sbjct: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694 Query: 1150 GTTYKVNVFGMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRA 1196 T Y+V+V+ + D S P G +T ++TT+ + E +T Sbjct: 1695 ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGF 1754 Query: 1197 EADIVLLVDGSWSIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNA 1255 + D V +G I R VRS+ I+ + D K L + + Sbjct: 1755 QVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDAST 1811 Query: 1256 HRDKKSLLQAVANLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLIT 1308 D S L+ +A P +TG + + + + + RPR IT Sbjct: 1812 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871 Query: 1309 DGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIV 1368 + + LK+ IG K DE+ +++ + H + D S + Sbjct: 1872 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKT 1930 Query: 1369 DDLT---INLCNSVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYP 1421 +T + N ++ PG + PS ++ E FR + P + + R++ YP Sbjct: 1931 PFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYP 1987 Query: 1422 VSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLN 1481 + G +E + + V L P + S ++ S+ Sbjct: 1988 PNVG--EEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQ----------------- 2028 Query: 1482 IYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEY 1541 TT + W P + YI+S PV E P + R+ T LT L Y Sbjct: 2029 ------TT--ISWAPFQDTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATY 2078 Query: 1542 AVTVQAV----LHDLTSEPVTV-REVTLPLPRPQDLKLRD---VTHSTMNVFWE 1587 + V+A+ H + E VTV V L +P D D V+H + WE Sbjct: 2079 NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2132 Score = 161 bits (407), Expect = 1e-38 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%) Query: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669 E +S + I+QE + VP P+DL F EVT W+P V Y + Sbjct: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944 Query: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 E P S +T ++ L P Y V A S PL ++TT+ AP N Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002 Query: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788 L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062 Query: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848 VS++ + TG T + G+ ++ T +T+ ++W+ AP + + Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119 Query: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907 P GGE +EVT D+ + V+ GL G +Y ++ L DA + Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176 Query: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960 P +L + DT + ++ S + GYR++ + + N E+ +H Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232 Query: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020 +NL P +Y +SV+ E P++ D L+ +TMRVTW P P Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291 Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077 + N+ V Y P + ++ VA+ + P+ + VL L P T Y ++V +Y+ E Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350 Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137 +G T SP + SD T +SF V W + GY++ HP R E V Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408 Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179 N++ L L GT Y V++ + +G E SPL+ + +T+SD Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449 Score = 155 bits (391), Expect = 8e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 Score = 147 bits (370), Expect = 2e-34 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%) Query: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 EQ L + P P D + +V WS + Y I Y + + Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733 P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ + Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917 Query: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792 T I WT V YR+ PV GE + + L P Y V Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977 Query: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852 PLT T+ P +L+ + T ST+ + W+ ++ Y +T Sbjct: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035 Query: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970 ++T+T+I WT AP R+ +K GE + + D+ ++ L P + Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148 Query: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028 Y ++ E + P+ T LS + + V+W + + YR+ Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208 Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086 P +G + V +S L P Y+++V + E S T Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266 Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145 P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P DN VVL Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 L GT Y V+V +++ ES+PL G++ T L T Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362 Score = 66.6 bits (161), Expect = 4e-10 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Query: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73 +L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859 Query: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133 + LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916 Query: 134 SVS 136 V+ Sbjct: 917 EVT 919 Score = 65.5 bits (158), Expect = 8e-10 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 7/118 (5%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82 E+D PS + + +N++ + W P+ GYR+T P GPTK T TE + Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600 Query: 83 ELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSA-WT 139 L P EYVV++ + + ES P+ +QT +T P T++ S+SA WT Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653 Score = 58.9 bits (141), Expect = 7e-08 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 ++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L Sbjct: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 L P +EY V++ + +ES G T+Q GSS P + +T I V WT Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108 Score = 53.5 bits (127), Expect = 3e-06 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82 V PP+DL F I +T+ ++WA P + + + P + E ++S S +L+ Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 83 ELVPETEYVVTITSYDEVEESVPVIGQ 109 L+P TEYVV+++S E ES P+ G+ Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353 Score = 50.1 bits (118), Expect = 3e-05 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 +D P+ ++F I N+ + W P I GYRI P G +E + S L+ Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEYVV+I + + EES +IGQ Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443 Score = 48.5 bits (114), Expect = 1e-04 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75 L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+ Sbjct: 1624 LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683 Query: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111 ++ ++S L+ T+Y V++ + + S P G +T Sbjct: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1719 Score = 45.1 bits (105), Expect = 0.001 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372 + Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849 Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 GS L++ ++++ DL +Y I++ A++ S P+ I ++T Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898 Score = 45.1 bits (105), Expect = 0.001 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70 A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106 + A + L P EY V++ + + +ESVP+ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259 Score = 45.1 bits (105), Expect = 0.001 Identities = 25/99 (25%), Positives = 45/99 (45%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 ++ ++ PSNL + + + ++W P + +TGY + + R+ P Sbjct: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1865 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425 T ++ L TEY I V A+K SEP+ +KT + Sbjct: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904 Score = 44.3 bits (103), Expect = 0.002 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%) Query: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 LL+ D P DL ++ +SW P + YRIT T + P +EFT+ Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498 Query: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130 S + +S L P +Y +T+ + TG P KP +TEI Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542 Query: 131 QKCSVSAWTDL 141 K S TD+ Sbjct: 1543 DKPSQMQVTDV 1553 Score = 42.7 bits (99), Expect = 0.005 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83 +D PS+L F N++ +SW P I GY I + P + TE ++ Sbjct: 1813 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1872 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEY + + + ++S P+IG+ Sbjct: 1873 LEPGTEYTIYVIALKNNQKSEPLIGR 1898 Score = 36.2 bits (82), Expect = 0.51 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64 L L + A +++++E V PP E T+ +SW + I G+++ P Sbjct: 1705 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1763 Query: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107 + T+ ++ L P T+Y + + + ++ S PV+ Sbjct: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1806 Score = 36.2 bits (82), Expect = 0.51 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 +V+ E V PP + + + ++W +TG++V P G ++ P Sbjct: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1775 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446 + ++ L T+Y+I + + S P V ++ S +D +++ FL Sbjct: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1824 Query: 447 GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494 S+ + ++ RA + + +E P +V R TE T+ Sbjct: 1825 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1870 Score = 35.0 bits (79), Expect = 1.1 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 V P DL F + + V + W P + GYR+ V P G + + T ++ Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118 L P Y + + ES P+ Q T + + T Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001 Score = 33.5 bits (75), Expect = 3.3 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101 +SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797 Query: 102 ESVPVIGQLTIQTGSSTKP 120 E L + T +T P Sbjct: 798 EQ-----SLILSTSQTTAP 811 Score = 32.7 bits (73), Expect = 5.7 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%) Query: 312 IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370 ++S V E+ L+ + V + P +L + + + ++W+ V Y++ Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484 Query: 371 MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423 S +V +T ++ L +Y I+V A+ G SS+PISI +T+ Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544 Query: 424 PMKVQV 429 P ++QV Sbjct: 1545 PSQMQV 1550 >gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] Length = 2176 Score = 342 bits (876), Expect = 4e-93 Identities = 349/1417 (24%), Positives = 571/1417 (40%), Gaps = 136/1417 (9%) Query: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876 + W+ P + +Y++ + P G +E T+ G + ++GLK G Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687 Query: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931 T++ + T+ + + GE T + + VT +IT +S W SA Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746 Query: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991 V G+RV ++ + + +LP A I +L P KY ++V+ GE + + Sbjct: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806 Query: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051 T VD+ + ++ V W + YR+VY P G +P T S Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866 Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106 L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T + Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166 W P V GY+V P G+ + + + L G TY VF + G ES Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225 PL Q+ T L T + ++ E D +LV W+ RA R + Sbjct: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035 Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270 +++GP + L P +E+ ++ K + LQ +++P Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093 Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330 Y T T + + + + G+RP EAP + D G Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136 Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390 + + P + Y + + R + + N V P L P+N Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179 Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446 L + VSW + + Y++ P +G G E V ++S +L P Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239 Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504 EY V+VY+V +D+ S P+ T P L ++GP TM V W P T ++ Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299 Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564 + Y PVK+ E E+ + P+ N + LT+L+P TEY V+V +V S P+ R+ T Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356 Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621 L P + D+T ++ V W + Y +R+ PE +E V S S +L Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415 Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681 +L T Y VS+ A++ ESP + Q++T P +L++ T +WD A Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474 Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740 V YRIT+ G +S E + G ++T L P Y +++ A+ + D S Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530 Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799 + + I T+ K P +QV + NS++VKW P+S V YR+T P G G +T Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588 Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859 T G Q + ++ L+P Y ++V + P GE + T + +L+ + ++ Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTS 1647 Query: 1860 LNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 1918 L+ +W Y++ P GP + + + +++ ++ L T Y V+V + Sbjct: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707 Query: 1919 EGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 1977 TL R +V + T ++ + W + ++V P +G P Sbjct: 1708 TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI 1767 Query: 1978 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 2037 + + P + R + L P T Y + L L + +P T P NLR T Sbjct: 1768 QRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATT 1825 Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV---ILQPLQPDTPYKIT 2094 NSL V+W + Y I Y P + VP R V + L+P T Y I Sbjct: 1826 PNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVTEATITGLEPGTEYTIY 1882 Query: 2095 VIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG 2154 VIA+ + L G +T E ++ +SW P Y I PVG Sbjct: 1883 VIALKNNQKSEPLIGRKKT-----------GQEALSQTTISWAPF-QDTSEYIISCHPVG 1930 Query: 2155 SN-EPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYD 2189 ++ EP++ V G TS TL L TY++ V A D Sbjct: 1931 TDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 1967 Score = 290 bits (741), Expect = 2e-77 Identities = 307/1304 (23%), Positives = 523/1304 (40%), Gaps = 97/1304 (7%) Query: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697 S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y Sbjct: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786 Query: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756 +VNV EDG S+ L+ +TT AP + V S + W++ + YRI+ Sbjct: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844 Query: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810 Y P G S E+ P TL +L P +Y +++ + TP+ TG + Sbjct: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904 Query: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868 + V +PRDL+ + T + + W+ V Y V PV G Q + + +T Sbjct: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963 Query: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928 V GL G Y V A+ L + TT + +P +L + TD+++ WT Sbjct: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020 Query: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988 + GYR++ L + N+ + NLQP ++Y +S+ A + E T Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079 Query: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048 G TT S E TE T+ +TW PAP + +++ RP +G + +V Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136 Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107 S V+ L P Y T+ + + G+ + + P NL ++P V+W Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195 Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165 E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255 Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225 S P+ + + T + + G + + A SI NF S + Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308 Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280 +V ++ A+ + P TE+ ++ S+ + + P +G ++ TG+ Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364 Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340 + I +F T + PRA G I ++ + + E Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423 Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400 + ++A + + + ++S + P +L + T S Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463 Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458 +SW P+ +V Y++ Y G QEF V +++ + LKP +Y + VY+V Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523 Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514 S+P+ +T + + DV ++ V+W P TGY ++ P Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583 Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574 PT+ K GP +M + L P EY V+V A S+P+ VT +P P DLK Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKF 1640 Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSLKDLFSQTLYT 1631 VT ++++ W P ++ Y VR TP+E +KE+ + +S + L T Y Sbjct: 1641 TQVTPTSLSAQWTPPNVQLTGYRVRV-TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699 Query: 1632 VSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWA 1690 VSV A+ D S P TT V P ++T+ T +W ++ +++ Sbjct: 1700 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1759 Query: 1691 PFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQ 1750 P ++ + D + L P T Y++ + + + S +I + + Sbjct: 1760 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI------ 1813 Query: 1751 APKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVL 1810 P NL+ T NSL V W P R+ Y I Y+ E + Sbjct: 1814 ---DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870 Query: 1811 QKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGN 1870 L+P T YTI V +L + + + GR KT + S + W + + Sbjct: 1871 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTG-----------QEALSQTTISWAPFQ-D 1918 Query: 1871 PRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDTSYTVTV 1913 +Y + P E L +PG + A L L +Y + V Sbjct: 1919 TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 1962 Score = 281 bits (718), Expect = 9e-75 Identities = 238/913 (26%), Positives = 398/913 (43%), Gaps = 39/913 (4%) Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444 L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L Sbjct: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056 Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502 +P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114 Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562 + L +P + E R G V ++ L P EY T+Q + + V +V Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170 Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617 PL P +L L + + V WE P I T + +E V ++ Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230 Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676 S + +L Y VSV V D+ ES P++ +T P VP PT+L+ T + + R TW Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288 Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734 S D++ + + ++P D E ++ +N +V NL P T Y VS++++Y ++ ES Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347 Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794 L G ++T P + + T+NS TV W + YRI + P G Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399 Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854 + + +NS+ L L P T Y +++ +L E + G+ T + R+L V Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458 Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913 + ++L + WD R Y++ Y G P + +PG+ + A + L+P YT+TV Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970 V GD +S R +QV + NS+ V+W P+ PV YRV +P Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578 Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030 +G P+++ + + +E L P Y V++ A GE P Q P + Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637 Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 2089 L+ T SLS W + + YR+ +P P+ E P ++V++ L T Sbjct: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696 Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 2148 Y+++V A+ + G T+ + PP+ ++D T +SW + G+++ Sbjct: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756 Query: 2149 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207 P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T Sbjct: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816 Query: 2208 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 2265 ++L+ ++ V W P RA T Y +K P R R T TGL P Sbjct: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876 Query: 2266 TDYGVTVFVQTPN 2278 T+Y + V N Sbjct: 1877 TEYTIYVIALKNN 1889 Score = 273 bits (698), Expect = 2e-72 Identities = 240/929 (25%), Positives = 400/929 (43%), Gaps = 47/929 (5%) Query: 1387 APSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS--GGKRQEFYVSRMETSTVLKDL 1444 +P +L E T + WTPP +V Y+V+ PV+ G Q +SR T + L Sbjct: 909 SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGL 967 Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TGY 1503 P Y V++V S+PL + T +L + +T+ V+W P TGY Sbjct: 968 SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGY 1027 Query: 1504 ILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVT 1563 L+ V T +P++ +GP+V+ L +L P +EY V++ A+ + S T T Sbjct: 1028 RLT---VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084 Query: 1564 LPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKD 1623 L +VT +T+ + W P P K VR E +EV D S Sbjct: 1085 LQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLT 1144 Query: 1624 LFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEG-FRGTWDHGAS-D 1681 + +YT+ V E ++P V T P+ PTNL + G +W+ + D Sbjct: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPD 1202 Query: 1682 VSLYRITWAPFGSS--DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 1739 ++ YRIT P + +E +++ D+++ F+NL+P Y VS+ + D+ Sbjct: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE------- 1255 Query: 1740 SERTLPILTTQAPK-SGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGEGNEQ 1797 ++PI T P P +L+ N +++ V W P S + + + Y P E + Sbjct: 1256 ---SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312 Query: 1798 TTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPST 1857 +I N+VVL L P T Y ++VSS+Y E + GR KT L++ + D + Sbjct: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITA 1371 Query: 1858 STLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVP 1915 ++ V W Y++ + P +G P E +P + N L NL P T Y V++V Sbjct: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVVSIVA 1430 Query: 1916 VYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTR 1975 + + T+ + R+++V TP SL + WD V YR+ Y G Sbjct: 1431 LNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNS 1489 Query: 1976 PSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS------GPR 2029 P + VPG+ + L P Y++ + A+ G+ SPA + + + P Sbjct: 1490 PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINYRTEIDKPS 1546 Query: 2030 NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 2089 ++V NS+SV W + PV YR+ +P G + T + + ++ LQP Sbjct: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1606 Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149 Y ++V A G+ L T + P ++ + T W P + GY++ Sbjct: 1607 EYVVSVYAQNPSGESQPLVQTAVTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1665 Query: 2150 YKPVGSNEPMEAF--VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207 P PM+ + +S + L +T Y+V+VYA D+ S P TTL NV Sbjct: 1666 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1724 Query: 2208 TDLKTYQIG---WDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263 + + ++ T + W + T +++ PA+G + T++ S+ TGL Sbjct: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1784 Query: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292 P TDY + ++ N V + T + Sbjct: 1785 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1813 Score = 262 bits (670), Expect = 3e-69 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%) Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445 +AP + + + S V W+ P + Y++ Y P G E + S L DL+ Sbjct: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871 Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498 P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P Sbjct: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931 Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554 A TGY + PV P E RL + N ++T L P Y V AV H S Sbjct: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986 Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613 +P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V Sbjct: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045 Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673 S + L++L + YTVS+ A+ ESP T TT + TEVT Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105 Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733 TW + + G + + T D ++V L P Y +I + Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158 Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790 G ER PI+ P S P NL + N + LTV W+ + + YRIT P+ Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213 Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849 G +GN + Q+S L P Y ++V ++ D E ++ + + Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272 Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907 LR + T+ V W + + + Y+P + + I + N +L NL P T Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332 Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967 Y V+V VY + + +T + + + T NS V W + YR+ Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391 Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027 + P + VP + + L L P T Y V++VAL + E +P ++ Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450 Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086 PR+L V T SL ++WD V+ YRI Y T G+ P+ E+ TVPG ++ + L+ Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509 Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142 P Y ITV AV GD ++ N RT + P + ++D V W PS SP Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200 V GY++ P P + + T T+ L P+ Y V+VYAQ SG S PL Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 2258 T TDLK Q+ + +W+P T YR++++P + T +EI + +S Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688 Query: 2259 FTGLSPDTDYGVTVF 2273 +GL T Y V+V+ Sbjct: 1689 VSGLMVATKYEVSVY 1703 Score = 260 bits (665), Expect = 1e-68 Identities = 246/918 (26%), Positives = 400/918 (43%), Gaps = 69/918 (7%) Query: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441 PG P N ++E T ++WTP +K+ P GG+ V+ S V+ Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140 Query: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496 L P EYV + V+ D E P+ T P +L++ D G T+ + Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556 TGY ++ P + +EV + + +L P EY V+V V D S P Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258 Query: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612 ++ + +P +P P DL+ ++ TM V W P P + ++VRY EEDV E+ + Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672 S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375 Query: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731 W + ++ YRI P S + E + N++ NL P T Y VSI A+ E Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435 Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791 ES LIG + T+ + PR+L+V AT SL + WD + V+ YRITY + Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486 Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846 G Q T+ G +++ + LKP YTITV ++ GR +KP++ Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541 Query: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902 ++V D ++++V+W + Y++ P G GP + + + Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601 Query: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960 LQP Y VV VY + G + +T + + +++ TP SL +W P Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1658 Query: 1961 VLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQG 2020 + YRV +P + T P + I + ++ V + L+ T Y V++ AL P+ Sbjct: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1718 Query: 2021 RTLPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNN 2079 TL S PR RV T +++++W + +++ P G + T P R+ Sbjct: 1719 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1778 Query: 2080 VILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPS 2139 I LQP T YKI + + ++ + + T + P N+ VSW P Sbjct: 1779 TITG-LQPGTDYKIYLYTLNDNARSSPVVIDASTA-IDAPSNLRFLATTPNSLLVSWQPP 1836 Query: 2140 PSPVLGYKIVYKPVGSNEPMEAFVGE---MTSYTLHNLNPSTTYDVNVYAQYDSGLSVPL 2196 + + GY I Y+ GS P E +T T+ L P T Y + V A ++ S PL Sbjct: 1837 RARITGYIIKYEKPGS-PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895 Query: 2197 TDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVR--GSE 2254 + KT Q + W+P + + Y + P GT + + R G+ Sbjct: 1896 ----------IGRKKTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRVPGTS 1944 Query: 2255 TSHCFTGLSPDTDYGVTV 2272 TS TGL+ Y + V Sbjct: 1945 TSATLTGLTRGATYNIIV 1962 Score = 213 bits (543), Expect = 2e-54 Identities = 155/567 (27%), Positives = 252/567 (44%), Gaps = 17/567 (2%) Query: 631 AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688 A PP DL F+ + + W+P ++ ++ + Y +++V + + S +VVL Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325 Query: 689 SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748 ++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383 Query: 749 RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807 + YRI + P G RE P ++ TL NL P T+Y VS++ L G Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443 Query: 808 AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866 +T V PRDL V T +++ +SW V+ Y +TY G QE TV G + Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501 Query: 867 NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922 + GLK G Y ++V A+ +G GD+ E P + D+ D SI Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559 Query: 923 AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982 W + V GYRV+ T K D IE LQP +Y +SV+A SG Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619 Query: 983 EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGR-GKQMVA 1041 E +PL A T + + LK + T ++ W P ++ YRV P + G Sbjct: 1620 ESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678 Query: 1042 KVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101 + P +S V+ L T Y+++V + + QG TT PR + +D T + Sbjct: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738 Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161 + ++W + G++V P + + + P + + L+ GT YK+ ++ + Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797 Query: 1162 DGGESSPLVGQEMTTLSDTTVMPILSS 1188 D SSP+V T + + + L++ Sbjct: 1798 DNARSSPVVIDASTAIDAPSNLRFLAT 1824 Score = 202 bits (515), Expect = 3e-51 Identities = 238/984 (24%), Positives = 396/984 (40%), Gaps = 98/984 (9%) Query: 1376 CNSVKGPGDLEAPSNLVISERTHR--SFRVSWTPPSDS-VDRYKVEYYPVSG-GKRQEFY 1431 C ++ P + I+E + S + W P S + +Y + + P + G+ +E Sbjct: 599 CQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEAT 658 Query: 1432 VSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKG--TEKTLPVPVVSLNIYDVGPTT 1489 + S +K LKP Y + S+ + + E + T + PV S + G TT Sbjct: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTV--TGETT 716 Query: 1490 MHVQWQPVGG---------ATGYILSYKPVKDT------------EPTRPKEVRLGPTVN 1528 + P+ A+ +++S+ DT E P+ + L T Sbjct: 717 ---PFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773 Query: 1529 DMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEP 1588 + + DL+P +Y V V + D + T P D + V +++ V W Sbjct: 774 SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSR 833 Query: 1589 VPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS--LKDLFSQTLYTVSVSAVHDEGESPPV 1646 + Y + Y +P + E++ ET+ S L DL Y +++ AV + ES PV Sbjct: 834 PQAPITGYRIVY-SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV 892 Query: 1647 TAQETTR------PVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 1700 Q+ T VP+P +L+ EVT W S V+ YR+ P + Sbjct: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ 952 Query: 1701 ILNGDENTLV-FENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPK-SGPRN 1758 L NT L+P Y + A+ P+ Q K P N Sbjct: 953 RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----------PLTAQQTTKLDAPTN 1002 Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818 LQ N T +++ V+W P ++ YR+T T G + +G + L+ L+P + Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061 Query: 1819 YTITVSSLYPDGEGGRMTGRGKT-------KPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871 YT+++ ++ + E + TG T P NT + + +T+ + W A P Sbjct: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-------EVTETTIVITWTPA---P 1111 Query: 1872 R-QYKLFYAPAAGG--PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDT 1928 R +KL P+ GG P E+ G+ ++ L P Y T+ V +G R + Sbjct: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSI---VVSGLTPGVEYVYTI-QVLRDGQE-RDAPI 1166 Query: 1929 GRTLMRGLARNVQVY---NPTPNSLDVRWDPAPGP-VLQYRVVYSPVDGTRPSE-SIVVP 1983 ++ L+ ++ NP L V W+ + P + YR+ +P +G + + VV Sbjct: 1167 VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226 Query: 1984 GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGETTNSLS 2042 + + L P Y+V++ + D E P +P P +LR +++ Sbjct: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--VPISDTIIPAVPPPTDLRFTNIGPDTMR 1284 Query: 2043 VAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYED 2101 V W + + + YSP + ++ N V+L L P T Y ++V +VYE Sbjct: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1344 Query: 2102 GDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG-SNEPME 2160 + L G +T GL P I SD F V W + + GY+I + P S P E Sbjct: 1345 HESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1403 Query: 2161 AFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDT 2219 V S TL NL P T Y V++ A S L Q +T+ DL+ + Sbjct: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS 1463 Query: 2220 FCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTVFVQTP 2277 + W +P YR+ G QE TV GS+++ +GL P DY +TV+ T Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523 Query: 2278 NLEGPG----VSVKEHTTV-KPTE 2296 + P +S+ T + KP++ Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQ 1547 Score = 200 bits (508), Expect = 2e-50 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%) Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542 P + +QW QP + YIL ++P R KE + +N + L P Y Sbjct: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679 Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584 +++Q H TS PVT VT PL + + ++T S+ V Sbjct: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738 Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642 W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE Sbjct: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798 Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702 + + T AP + + +V W + ++ YRI ++P E L Sbjct: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858 Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758 N++ +L P Y ++I A+ ++ + +I E TT P+S PR+ Sbjct: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912 Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818 LQ T +T+ W P V YR+ P G R + L P Sbjct: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972 Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878 Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L Sbjct: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031 Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938 G + + + LRNLQP + YTV++V + + + + TL G Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089 Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991 ++ YN T ++ + W PAP + V S P + T S SIVV G Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142 Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049 L P Y V + + DG+ +P + + P S P NL + T L+V+W+ + Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199 Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105 P + YRI +PT G+ ++E V +++ L P Y ++V V +D + Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257 Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162 ++ + + PP ++ ++ RV+W P PS + + + Y PV + E + + Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316 Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222 + L NL P T Y V+V + Y+ S PL + T + T + I ++F V Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376 Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280 W +P T YR++ P R +E V S S T L+P T+Y V++ E Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436 Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304 P + + + +TV P + TP Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461 Score = 184 bits (468), Expect = 9e-46 Identities = 215/925 (23%), Positives = 375/925 (40%), Gaps = 86/925 (9%) Query: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390 + V P +L +EV+ V + W P S VTGY+V + P+ G L + + T Sbjct: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963 Query: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450 V LS Y V A+ S+P++ + T+ +D ++ F V+ + S Sbjct: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510 + + RA +I+ R+ + L T + + ++ +++ + Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051 Query: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570 P R N A Y + + KG++ + PK + T + + ++ + + Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104 Query: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625 I +G K VR A + ++ + + T + ++ A Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164 Query: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678 I K P P +L G T +W ++ Y IT G + + V Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738 A +S +L P Y V+V +D S+P++ +T P +L+ T+ D+ Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282 Query: 739 FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796 ++TW P + + + Y PV E E++ P+ L NL+P T+Y VSV Y Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342 Query: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855 TPL G T +P + SD T ++ + W + Y + + P G Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400 Query: 856 TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915 +E V + L L GT+Y +S+ AL L G+ +T+ + P+DL Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458 Query: 916 ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975 T TS+ W + VR YR+++ + E +P I L+P Y I+V Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518 Query: 976 FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031 +A G+ +P++ + TE+ + S+ ++V + +N++ V W P+ V YRV Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577 Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089 P +G G P T ++ LQP Y ++V GE + L Q + TT + Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA 1634 Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149 P +LK + T +S W P ++ GY+V P + E+ + P ++VV+ L Sbjct: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694 Query: 1150 GTTYKVNVFGMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRA 1196 T Y+V+V+ + D S P G +T ++TT+ + E +T Sbjct: 1695 ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGF 1754 Query: 1197 EADIVLLVDGSWSIGRANFRTVRSF 1221 + D V +G I R VRS+ Sbjct: 1755 QVDAV-PANGQTPIQRTIKPDVRSY 1778 Score = 177 bits (449), Expect = 1e-43 Identities = 148/554 (26%), Positives = 237/554 (42%), Gaps = 29/554 (5%) Query: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693 P+DL T +W V Y ITY E G+ V P S ++ +S LKP Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510 Query: 694 ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749 Y + V A G S P++ TE K P ++VTD +S + W + Sbjct: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1568 Query: 750 VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808 V YR+ P G G ++ T P+Q T+E L P +Y VSV + SG PL A Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628 Query: 809 ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAG-GETQEVTVRGDTTN 867 T P DL+ + T +++ W+ ++ Y V TP G +E+ + D+++ Sbjct: 1629 VTTIPA--PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSS 1686 Query: 868 TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927 V+ GL T+Y +SV AL + G TTLE P+ D T+T+I W + Sbjct: 1687 VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRT 1746 Query: 928 APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987 + G++V ++ + D I LQP T Y+I ++ + P+ Sbjct: 1747 KTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1805 Query: 988 TGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPT 1046 DA+T + S L+ T N++ V+W+P ++ Y + Y +P +++V + P Sbjct: 1806 VIDASTAIDAPSN-LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864 Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106 VT + L+P T Y I V+ + K Q S R KT +S ++ Sbjct: 1865 VTEATITGLEPGTEYTIYVIAL------KNNQKSEPLIGR------KKTGQEALSQTTIS 1912 Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166 W P + Y ++ HP G D + V + L L G TY + V + D + Sbjct: 1913 WAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--QQ 1969 Query: 1167 SPLVGQEMTTLSDT 1180 V +E+ T+ ++ Sbjct: 1970 RHKVREEVVTVGNS 1983 Score = 161 bits (407), Expect = 1e-38 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%) Query: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669 E +S + I+QE + VP P+DL F EVT W+P V Y + Sbjct: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944 Query: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728 E P S +T ++ L P Y V A S PL ++TT+ AP N Sbjct: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002 Query: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788 L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062 Query: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848 VS++ + TG T + G+ ++ T +T+ ++W+ AP + + Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119 Query: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907 P GGE +EVT D+ + V+ GL G +Y ++ L DA + Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176 Query: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960 P +L + DT + ++ S + GYR++ + + N E+ +H Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232 Query: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020 +NL P +Y +SV+ E P++ D L+ +TMRVTW P P Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291 Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077 + N+ V Y P + ++ VA+ + P+ + VL L P T Y ++V +Y+ E Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350 Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137 +G T SP + SD T +SF V W + GY++ HP R E V Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408 Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179 N++ L L GT Y V++ + +G E SPL+ + +T+SD Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449 Score = 155 bits (391), Expect = 8e-37 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%) Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735 S +S Y + W P S + E + G N+ + L P +YE +SI E Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695 Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788 D + + P+ TT + V T++S V W AS V +R+ Y+ Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755 Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848 S Q + SV + L P Y + V + DGE + +T + Sbjct: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815 Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908 + V +++ VRW + Y++ Y+P+ G + +P N L +LQP Sbjct: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875 Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962 Y +T+ V + T+ T R+ R++Q T + + W P V Sbjct: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935 Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021 YRV PV+ + + + NT + L P Y + A+ E P AQ + Sbjct: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993 Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081 T P NL+ ET +++ V W + YR+ T +Y P + Sbjct: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052 Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138 L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107 Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189 +P+P +G+K+ +P E + S + L P Y + D Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167 Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246 + + PL+ T L+L D + W+ S T YR+ +P +G +G Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221 Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306 E V ++S F LSP +Y V+V+ +VK+ P P PPP Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270 Score = 147 bits (370), Expect = 2e-34 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%) Query: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678 EQ L + P P D + +V WS + Y I Y + + Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857 Query: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733 P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ + Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917 Query: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792 T I WT V YR+ PV GE + + L P Y V Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977 Query: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852 PLT T+ P +L+ + T ST+ + W+ ++ Y +T Sbjct: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035 Query: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912 G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094 Query: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970 ++T+T+I WT AP R+ +K GE + + D+ ++ L P + Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148 Query: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028 Y ++ E + P+ T LS + + V+W + + YR+ Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208 Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086 P +G + V +S L P Y+++V + E S T Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266 Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145 P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P DN VVL Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181 L GT Y V+V +++ ES+PL G++ T L T Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362 Score = 140 bits (352), Expect = 3e-32 Identities = 176/796 (22%), Positives = 303/796 (38%), Gaps = 82/796 (10%) Query: 334 VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392 V PP++L + +++ W P PS +T + V +P+ LS+ P + + Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 393 DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450 +L TEY +SVS++ S P+ +KT G+D I F + S++ Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375 Query: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHTE--FTLKKFTKVEDIIEAI 507 + +++ RA + + I + S + R PH+ TL T + + +I Sbjct: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428 Query: 508 NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565 R S + + + + S+VP+ + ++ +S ++ PA+ +R Sbjct: 1429 VALNGREESP------------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476 Query: 566 -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614 NS V+ F V +S P + TV + S ++ Sbjct: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532 Query: 615 SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672 I + E+ P + ++V W P+ V Y +T K G Sbjct: 1533 PISINYRTEIDK--------PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584 Query: 673 DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732 + P T + + L+P Y+V+V A+ G S PL +T AP +LK T Sbjct: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV--QTAVTTIPAPTDLKFT 1641 Query: 733 DETTDSFKITWTQAPGRVLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVS 791 T S WT ++ YR+ P G +E+ P+ + L+ TKYEVS Sbjct: 1642 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1701 Query: 792 VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV 851 V + P G T E PR RV+D T +T+ +SW + + V P Sbjct: 1702 VYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA 1761 Query: 852 AGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDL 911 G + T++ D + + GL+ GT Y + + L + + + +T + +P +L Sbjct: 1762 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID--APSNL 1819 Query: 912 VTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKY 971 T S+ W + GY + ++ I L+P T+Y Sbjct: 1820 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1879 Query: 972 RISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031 I V A ++ + EPL G K +E + ++W P Y + Sbjct: 1880 TIYVIALKNNQKSEPLIG-----------RKKTGQEALSQTTISWAPFQ-DTSEYIISCH 1927 Query: 1032 PHGRGKQ-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSP 1090 P G ++ + +VP T TS L L TY+I V + K+R+ T + Sbjct: 1928 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 1987 Query: 1091 RNLKTSDPTMSSFRVT 1106 N T D + V+ Sbjct: 1988 LNQPTDDSCFDPYTVS 2003 Score = 66.6 bits (161), Expect = 4e-10 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%) Query: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73 +L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859 Query: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133 + LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916 Query: 134 SVS 136 V+ Sbjct: 917 EVT 919 Score = 65.5 bits (158), Expect = 8e-10 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 7/118 (5%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82 E+D PS + + +N++ + W P+ GYR+T P GPTK T TE + Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600 Query: 83 ELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSA-WT 139 L P EYVV++ + + ES P+ +QT +T P T++ S+SA WT Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653 Score = 58.9 bits (141), Expect = 7e-08 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83 ++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L Sbjct: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139 L P +EY V++ + +ES G T+Q GSS P + +T I V WT Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108 Score = 53.5 bits (127), Expect = 3e-06 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82 V PP+DL F I +T+ ++WA P + + + P + E ++S S +L+ Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326 Query: 83 ELVPETEYVVTITSYDEVEESVPVIGQ 109 L+P TEYVV+++S E ES P+ G+ Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353 Score = 50.1 bits (118), Expect = 3e-05 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 +D P+ ++F I N+ + W P I GYRI P G +E + S L+ Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEYVV+I + + EES +IGQ Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443 Score = 48.5 bits (114), Expect = 1e-04 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%) Query: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75 L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+ Sbjct: 1624 LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683 Query: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111 ++ ++S L+ T+Y V++ + + S P G +T Sbjct: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1719 Score = 45.1 bits (105), Expect = 0.001 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%) Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372 + Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849 Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 GS L++ ++++ DL +Y I++ A++ S P+ I ++T Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898 Score = 45.1 bits (105), Expect = 0.001 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70 A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223 Query: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106 + A + L P EY V++ + + +ESVP+ Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259 Score = 44.7 bits (104), Expect = 0.001 Identities = 25/96 (26%), Positives = 44/96 (45%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 ++ ++ PSNL + + + ++W P + +TGY + + R+ P Sbjct: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1865 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422 T ++ L TEY I V A+K SEP+ +KT Sbjct: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1901 Score = 44.3 bits (103), Expect = 0.002 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%) Query: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74 LL+ D P DL ++ +SW P + YRIT T + P +EFT+ Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498 Query: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130 S + +S L P +Y +T+ + TG P KP +TEI Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542 Query: 131 QKCSVSAWTDL 141 K S TD+ Sbjct: 1543 DKPSQMQVTDV 1553 Score = 42.7 bits (99), Expect = 0.005 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83 +D PS+L F N++ +SW P I GY I + P + TE ++ Sbjct: 1813 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1872 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109 L P TEY + + + ++S P+IG+ Sbjct: 1873 LEPGTEYTIYVIALKNNQKSEPLIGR 1898 Score = 36.2 bits (82), Expect = 0.51 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64 L L + A +++++E V PP E T+ +SW + I G+++ P Sbjct: 1705 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1763 Query: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107 + T+ ++ L P T+Y + + + ++ S PV+ Sbjct: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1806 Score = 36.2 bits (82), Expect = 0.51 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%) Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386 +V+ E V PP + + + ++W +TG++V P G ++ P Sbjct: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1775 Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446 + ++ L T+Y+I + + S P V ++ S +D +++ FL Sbjct: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1824 Query: 447 GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494 S+ + ++ RA + + +E P +V R TE T+ Sbjct: 1825 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1870 Score = 35.0 bits (79), Expect = 1.1 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%) Query: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83 V P DL F + + V + W P + GYR+ V P G + + T ++ Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966 Query: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118 L P Y + + ES P+ Q T + + T Sbjct: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001 Score = 33.5 bits (75), Expect = 3.3 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%) Query: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101 +SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797 Query: 102 ESVPVIGQLTIQTGSSTKP 120 E L + T +T P Sbjct: 798 EQ-----SLILSTSQTTAP 811 Score = 32.7 bits (73), Expect = 5.7 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%) Query: 312 IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370 ++S V E+ L+ + V + P +L + + + ++W+ V Y++ Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484 Query: 371 MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423 S +V +T ++ L +Y I+V A+ G SS+PISI +T+ Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544 Query: 424 PMKVQV 429 P ++QV Sbjct: 1545 PSQMQV 1550 >gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo sapiens] Length = 921 Score = 333 bits (854), Expect = 2e-90 Identities = 202/575 (35%), Positives = 274/575 (47%), Gaps = 81/575 (14%) Query: 2508 CPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTAD 2567 CP I + PGF ++ + + + AS + + GS AY++ N PT + Sbjct: 44 CPKIRIGQDDLPGFDLISQFQVDKA--ASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRN 101 Query: 2568 LHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTR 2627 L+P+GLP Y+ + FR+ T + IWQI D K QVG+ + ++++ F K Sbjct: 102 LYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLD 161 Query: 2628 GEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEI 2687 G +QT F + +LF +HK+ I V S +++DC I IK G I DG+ + Sbjct: 162 GSLQTAAFSN--LSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAV 219 Query: 2688 LGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVG 2747 LGKL + S F++Q I C P+ R+ C ++P+R P+ G Sbjct: 220 LGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARIT----PSQTTDERGPPGEQG 275 Query: 2748 PPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQG 2806 PPGPPGP G PG G G+RG G GPPGP G+ G PG G PG G +GL+ P G G Sbjct: 276 PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPG 335 Query: 2807 RQGMKGDAGEPGLPGRTGTPGL--------------------------------PGPPGP 2834 G KG GEPG+PG G PG PGPPGP Sbjct: 336 SIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGP 395 Query: 2835 MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGD 2894 GP G GF D PPG G PG PG+ G G G+ G+ GR G G +G++G+ Sbjct: 396 PGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE 455 Query: 2895 RGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAG 2954 G++ +Q P Q R G G G G+ G Sbjct: 456 LGEVGAQG----------------------------PPGAQGLRGITGIVGDKGEKGARG 487 Query: 2955 ARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGES----- 3009 GEPGP G PG PG G +GPPGE G G++ G+ G RG+PG PGP+G++ Sbjct: 488 LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR-----GAEGARGIPGLPGPKGDTGLPGV 542 Query: 3010 --RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 R G PG G++G PG PG PG++G++G PG PG Sbjct: 543 DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577 Score = 253 bits (647), Expect = 2e-66 Identities = 148/353 (41%), Positives = 177/353 (50%), Gaps = 45/353 (12%) Query: 2742 TQDSVGPPGPPGPAGG---------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 T+ G PGPPG AG PGAKG GE+G +GA G PG G+ G PG QGPPG Sbjct: 554 TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 613 Query: 2793 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--------------- 2836 GP G +PG +G G G G PG G G+PGLPG PGP G Sbjct: 614 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 673 Query: 2837 PPGDRGFTGKDGAMGPRGP------PGPPGS---PGSPGVTGPSGKPGKPGDHGRPGPSG 2887 P G++G +G++G G RG PGP GS PG PG+ GP G G PG G GP G Sbjct: 674 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 733 Query: 2888 LKGEKGDRGDIASQNMMRAVAR--------QVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939 +G +G++G + R QVC ++I L + + Sbjct: 734 PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 793 Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGL 2999 +PGPPGPPGPPG G G+ G G PG G PG G G +G GEKGERG GP GL Sbjct: 794 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGL 853 Query: 3000 PGP---PGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQC 3049 PG PG G + G G G RGPPG G PG G GPPG PG+C+ + C Sbjct: 854 PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906 Score = 232 bits (591), Expect = 5e-60 Identities = 149/358 (41%), Positives = 174/358 (48%), Gaps = 41/358 (11%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P PN+C + G PG PG G GAKG GE G G G G +G++G G QGPPG Sbjct: 409 PLCPNACPPGRS--GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 466 Query: 2793 PQGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK-- 2846 QG G++ GE+G +G+ G+ G GLPG G G GPPG GP GDRG G Sbjct: 467 AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 526 Query: 2847 -DGAMGPRGPPGPPGS------PGSPGVTGPSGKPGKPGDHGR---------PGPSGLKG 2890 G GP+G G PG PG PG G GKPG PGD G PG G+ G Sbjct: 527 IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG 586 Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950 EKG G M + GQ ++ + P SR + GP G PG P Sbjct: 587 EKGSTGAPGKPGQMGNSGKP-------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 639 Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPRGLPGP---P 3003 G G+ G PG G PG PG PGM+G G G PG KGE+G G +G RG G P Sbjct: 640 GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 699 Query: 3004 GPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GP+G + G PG G RGP G G PG G RGPPGP G +P QG PG Sbjct: 700 GPKGSA--GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP-GVQGPPG 754 Score = 212 bits (539), Expect = 5e-54 Identities = 148/393 (37%), Positives = 168/393 (42%), Gaps = 101/393 (25%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---PRGDIG------------------PP 2785 G PG G G PG GP+G+RG GA G PG P+GD G P Sbjct: 499 GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558 Query: 2786 GPQGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844 G GPPG G GL +PG G +G+ G+ G G PG+ G G G PG GPPG+ G Sbjct: 559 GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 618 Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 2904 G G G RG GP GSPG PG G G PG PG PGP GL G KGDRG + Sbjct: 619 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPK 675 Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG---P 2961 EQ SG+ + R + G G PGP GSAG GEPG P Sbjct: 676 G-------EQGASGEEGEAGE------------RGELGDIGLPGPKGSAGNPGEPGLRGP 716 Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG------------------------------- 2990 G G PG G +GPPG RG+ GE+G G Sbjct: 717 EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 776 Query: 2991 ------------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGP- 3037 TG G G PGPPGP GE+ G PG G RG PG G PG G+RGP Sbjct: 777 MAASLKRPDSGATGLPGRPGPPGPPGPPGEN--GFPGQMGIRGLPGIKGPPGALGLRGPK 834 Query: 3038 --------PGPPGYCDSSQCASIPYNGQGYPGS 3062 GPPG + +I G P S Sbjct: 835 GDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 867 Score = 107 bits (268), Expect = 1e-22 Identities = 79/245 (32%), Positives = 90/245 (36%), Gaps = 95/245 (38%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL------ 2799 VG PGP G G G +G GERG G IG PGP+G G PG G GP+G GL Sbjct: 669 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 728 Query: 2800 -------SIPGEQGRQGMKGDAGEPGLP------------------------------GR 2822 + GEQG G+ G G PG G Sbjct: 729 RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788 Query: 2823 TGTPGLPGPPGPMGPPGDRGFTGK------------DGAMGPRGPPG---------PPGS 2861 TG PG PGPPGP GPPG+ GF G+ GA+G RGP G PPG Sbjct: 789 TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 848 Query: 2862 -------------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890 PG G+ G G PG PG G P+ Sbjct: 849 GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 908 Query: 2891 EKGDR 2895 + G R Sbjct: 909 QAGQR 913 Score = 84.3 bits (207), Expect = 2e-15 Identities = 51/121 (42%), Positives = 60/121 (49%), Gaps = 25/121 (20%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG------PRGDIGPPGPQGPPGPQGPNGL- 2799 GPPGPPGP G G G G RG+ G GPPG P+GD+G G +GPPG +GPNGL Sbjct: 796 GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 854 Query: 2800 ---SIPGEQG-----RQGMKGDAGEPGL---------PGRTGTPGLPGPPGPMGPPGDRG 2842 +PG+ G R G G+ G PG+ PG G PG P G R Sbjct: 855 GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 914 Query: 2843 F 2843 F Sbjct: 915 F 915 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 278 bits (710), Expect = 8e-74 Identities = 194/651 (29%), Positives = 277/651 (42%), Gaps = 136/651 (20%) Query: 2500 VCETATSSCPLIYLDGY--TSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQK 2557 V + SCP++ ++G+ T LE + S++ ES + +++ Sbjct: 26 VRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLGDSFSLRRAFCESDK----TCFKLG- 80 Query: 2558 NAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSK 2617 +A + + T + P GLP Y++ +FR+ + + +WQ+ ++ PQ+ ++ D K Sbjct: 81 SALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNIPQISIVVDGGKK 140 Query: 2618 TLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEA 2677 + F + T G+V F E++ LF +HK+ I + S+ + +Y+DC I + E Sbjct: 141 VVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMDCNLIARRQTDEK 200 Query: 2678 GNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCP---- 2733 + G ++ + K ++ I CS +++ CC+I + KCP Sbjct: 201 DTVDFHGRTVIA-TRASDGKPVDIELHQLKIYCSANLIAQETCCEI----SDTKCPEQDG 255 Query: 2734 ------------------------AFPNSCTC--TQDSVGPPGPPGPAGGPGAKGPRGER 2767 + C C + G PG PG G G KG GE Sbjct: 256 FGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGEN 315 Query: 2768 GISGAIGPPGPRGDIGPPGPQGPPGPQGPNG----LSIPGEQGRQGMKGDA---GEPGLP 2820 G+ GA G PG +G+ G G +G G +G G ++ G G G+KGD G PG Sbjct: 316 GLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPK 375 Query: 2821 GRTGTPGLPGPP---------GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGV---- 2867 G G G PGPP GP GPPG G G+ G GP G PGPPG PG PG+ Sbjct: 376 GEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIH 435 Query: 2868 ----------------------TGPSGKPGKPGDHGRPGPSGLKGE------KGDRGDIA 2899 G G+ G PG G GP G KGE KG++GD Sbjct: 436 QTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRG 495 Query: 2900 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 2959 ++ + Q + +PG PGPPG GS G +G+ Sbjct: 496 EPGVIGS----------------------------QGVKGEPGDPGPPGLIGSPGLKGQQ 527 Query: 2960 ------GPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGP---PGPQGESR 3010 GP G PG G PG G PG++G+ GEKG+ G G GP GLPGP GP G+S Sbjct: 528 GSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-GIIGPPGLPGPKGEAGPPGKSL 586 Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG G+ G PGP G G G+ G G PG I G G PG Sbjct: 587 PGEPGLDGNPGAPGPRGPKGERGLPGVHGSPG--------DIGPQGIGIPG 629 Score = 214 bits (544), Expect = 1e-54 Identities = 143/358 (39%), Positives = 161/358 (44%), Gaps = 106/358 (29%) Query: 2746 VGPPGPPGPAGGPGAKGPRG------ERGISGAIGPPGP------RGDIGPPGPQGPPGP 2793 +GP GPPGP G G GP G GI G GPPG RG GPPG GPPGP Sbjct: 366 LGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGP 425 Query: 2794 QGPNGL-----SIPG----------EQGRQGMKGDAGEPGLPGRTGT------PGLPGPP 2832 GP G+ ++ G E G+KGD GE GLPG G+ G PG P Sbjct: 426 PGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEP 485 Query: 2833 GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG---SPGVTG------------PSGKPGKP 2877 G GDRG G G+ G +G PG PG PG SPG+ G P G G P Sbjct: 486 FTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLP 545 Query: 2878 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSS 2937 G+HG PG G+KGEKGD G I Sbjct: 546 GEHGIPGKQGIKGEKGDPGGII-------------------------------------- 567 Query: 2938 RNQPGPPGPPGPPGSAGARGE--PGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----- 2990 GPPG PGP G AG G+ PG G G PG PG +GP GERGLPG G G Sbjct: 568 ----GPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQ 623 Query: 2991 -------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041 TG+ GP G PG GP+G G PG+ G+ G G PGR G G+ GPPG P Sbjct: 624 GIGIPGRTGAQGPAGEPGIQGPRG--LPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDP 679 Score = 212 bits (539), Expect = 5e-54 Identities = 142/385 (36%), Positives = 163/385 (42%), Gaps = 101/385 (26%) Query: 2746 VGPPGPPGPAG--GPGAKGPRGERGISG---AIGPPGPRGDIGPPGPQGPPGPQGPNGLS 2800 +GPPG PGP G GP K GE G+ G A GP GP+G+ G PG G PG GP G+ Sbjct: 567 IGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIG 626 Query: 2801 IPGEQGRQGMKGDAG------------EPGLPGRTGTPGLPGPPGPMGPPGD-------- 2840 IPG G QG G+ G PG PG G PG G PG GPPGD Sbjct: 627 IPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLG 686 Query: 2841 ------RGFTG-----------------------------KDGAMGPRGPPGPPGS---- 2861 + F G + G +GPRGPPG PG Sbjct: 687 DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPK 746 Query: 2862 -----------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDI 2898 PG PG GP+G PG G G PGP+G KGEKG G Sbjct: 747 GSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPP 806 Query: 2899 ASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE 2958 E+ + + +N +P + PGPPGPPGP G G GE Sbjct: 807 GKPGPPGPPGIPFNERNGMSSLYKIKGGVN-VP-------SYPGPPGPPGPKGDPGPVGE 858 Query: 2959 PGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGST 3017 PG G PG G PG++G G G PG G SG G PGPPG GE GP G Sbjct: 859 PGAMGLPGLEGFPGVKGDRGPAGPPGI-----AGMSGKPGAPGPPGVPGEPGERGPVGDI 913 Query: 3018 GSRGPPGPPGRPGNSGIRGPPGPPG 3042 G GP GP G+PG +G G PG G Sbjct: 914 GFPGPEGPSGKPGINGKDGIPGAQG 938 Score = 211 bits (537), Expect = 9e-54 Identities = 140/367 (38%), Positives = 158/367 (43%), Gaps = 104/367 (28%) Query: 2747 GPPGPPGPAGGPGA----------------------KGPRGERGISGAIGPPGP------ 2778 G PG PGP G P A G + +G G G PG Sbjct: 668 GKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMAR 727 Query: 2779 RGDIGPPGPQGPPGPQGPNGLS-------IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 2831 +GDIGP GP G PG +GP G IPGE+G +G++G G PG PG TG PGL G Sbjct: 728 KGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGR 787 Query: 2832 PGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP-----------------------GSPGVT 2868 G GP G +G G DG G GPPGPPG P G PG Sbjct: 788 TGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPP 847 Query: 2869 GPSGKPG---KPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925 GP G PG +PG G PG G G KGDRG Sbjct: 848 GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG-------------------------- 881 Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGPGGRPGFPGTPGMQGPPGE 2979 P +PG PGPPG PG G RG PGP G G PG G G PG Sbjct: 882 -----PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA 936 Query: 2980 RGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPP 3038 +G+ G+ G+RG G G +G+PG G QGE G PG TG +G GP G PGN G G P Sbjct: 937 QGIMGKPGDRGPKGERGDQGIPGDRGSQGER--GKPGLTGMKGAIGPMGPPGNKGSMGSP 994 Query: 3039 ---GPPG 3042 GPPG Sbjct: 995 GHQGPPG 1001 Score = 208 bits (530), Expect = 6e-53 Identities = 147/410 (35%), Positives = 166/410 (40%), Gaps = 118/410 (28%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SI 2801 +GP GPPG G G KG +GERG G G G G G PG G PGP GP GL Sbjct: 731 IGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGH 790 Query: 2802 PGEQGRQGMKGDAGEPGLPGRTGTPGL-----------------------PGPPGPMGPP 2838 PG G +G KG G PG PG G PG+ PGPPGP GP Sbjct: 791 PGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPK 850 Query: 2839 GDRGFTGKDGAM---------------GPRGPPGPPGSPGSPGVTGPSGKPGKP------ 2877 GD G G+ GAM GP GPPG G G PG GP G PG+P Sbjct: 851 GDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPV 910 Query: 2878 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQ-IPND--Y 2934 GD G PGP G G+ G G + + G + +Q IP D Sbjct: 911 GDIGFPGPEGPSGKPGINGKDGIPGAQGIMGK-------PGDRGPKGERGDQGIPGDRGS 963 Query: 2935 QSSRNQP---------GPPGPPGPPGSAGARGEPGPGGRPGFPGTP-------------- 2971 Q R +P GP GPPG GS G+ G GP G PG PG P Sbjct: 964 QGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYIN 1023 Query: 2972 ------------------------------GMQGPPGERGLPGEKGERGTGSSGPRGLPG 3001 G GPPG+ GLPG G+ GP+G G Sbjct: 1024 QEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD-----PGPQGYRG 1078 Query: 3002 PPGPQGESRTGPPGSTGSRGPP--GPPGRPGNSGIRGPPGPPGYCDSSQC 3049 G +GE G PGS G G G PG PG G +GPPGP G C+ C Sbjct: 1079 QKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128 Score = 145 bits (367), Expect = 5e-34 Identities = 100/296 (33%), Positives = 115/296 (38%), Gaps = 100/296 (33%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP---PGPRGDIGPPGPQ- 2788 PA P G PGPPG G PG +GP G+ G G GP PG G G PG Q Sbjct: 879 PAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQG 938 Query: 2789 --GPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK 2846 G PG +GP GE+G QG+ GD G G G+ G G+ G GPMGPPG++G G Sbjct: 939 IMGKPGDRGPK-----GERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS 993 Query: 2847 DGAMGPRGPPGPPGSPGSP----------------------------------------- 2865 G GP G PG PG P Sbjct: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 Query: 2866 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925 G GP GK G PG G PGP G +G+KG+RG+ Sbjct: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI------------------------- 1088 Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERG 2981 G PG PG PG++ G PG PG PG QGPPG G Sbjct: 1089 ----------------GLPGSPGLPGTSAL-------GLPGSPGAPGPQGPPGPSG 1121 Score = 85.5 bits (210), Expect = 7e-16 Identities = 56/153 (36%), Positives = 63/153 (41%), Gaps = 49/153 (32%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISG---------------------------------- 2771 +GPPG G G PG +GP G GI G Sbjct: 982 MGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 Query: 2772 ----------AIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPG 2821 A G PGP G G PGP G PGPQG G GE+G G+ G G PGLPG Sbjct: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK--GERGEPGI-GLPGSPGLPG 1098 Query: 2822 RT--GTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 + G PG PG PGP GPPG G + + P Sbjct: 1099 TSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 Score = 56.2 bits (134), Expect = 5e-07 Identities = 32/77 (41%), Positives = 35/77 (45%), Gaps = 10/77 (12%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGI----------SGAIGPPGPRGDIGPPGPQGPPGPQGP 2796 GPPG PGP G G KG RGE GI + A+G PG G GP GP GP G P Sbjct: 1066 GPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 Query: 2797 NGLSIPGEQGRQGMKGD 2813 P Q G+ Sbjct: 1126 EDCLYPVSHAHQRTGGN 1142 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 264 bits (675), Expect = 9e-70 Identities = 154/345 (44%), Positives = 181/345 (52%), Gaps = 47/345 (13%) Query: 2747 GPPGPPGPAGGPGAKGPRGERG---ISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IP 2802 GPPG G G GA GPRGE G + G G PG GD GP GPQGP GP+GP G + P Sbjct: 720 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779 Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPG---PPGPMGPPGDRGFTGKDGA---------- 2849 G G G G G+ G G G+PGLPG P GP G PG++G GK+G Sbjct: 780 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 839 Query: 2850 --------MGPRGPPGPPGSPGSPGVTG---------PSGKPGKPGDHGRPGPSGLKGEK 2892 G +GPPG G PG PG+ G P G PG+ G G PGP G G Sbjct: 840 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 899 Query: 2893 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-QSSRNQPGPPGPPGP-- 2949 G RG+ S +R R + E+L R +L Q+P Y +SS+ +PGPPGPPG Sbjct: 900 GLRGESPSMETLR---RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 956 Query: 2950 -PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTG---SSGPRGLPGPPGP 3005 PG AG GEPG G+ G G G GP GERG G+ G G G GP G+PG PG Sbjct: 957 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1016 Query: 3006 QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 3050 G ++ G PG G +G GP G PG + GPPGPPG CD SQCA Sbjct: 1017 PGYAKDGLPGIPGPQGETGPAGHPG---LPGPPGPPGQCDPSQCA 1058 Score = 247 bits (630), Expect = 1e-64 Identities = 142/314 (45%), Positives = 164/314 (52%), Gaps = 67/314 (21%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIPGEQ 2805 G PG PG G PG GP G GI+GA GPPG +G PG +GPPGPQGP+GL IPGE+ Sbjct: 633 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGLPGIPGEE 689 Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------PGPP 2859 G++G G G PG PG+ G PGLPGP G GPPG +G TG GA GPRG PG Sbjct: 690 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 749 Query: 2860 GSPGSPGVTGPS------------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 G PG G TGP+ GK G PG G PGPSG G+KG +G+ S + Sbjct: 750 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---- 805 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967 PG GP GPPG G +G PG G PG Sbjct: 806 ---------------------------------PGFLGPRGPPGEPGEKGVPGKEGVPGK 832 Query: 2968 PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGP 3022 PG PG + GERG PG KG++G G G G PG PG +G + G PG G GP Sbjct: 833 PGEPGFK---GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 889 Query: 3023 PGPPGRPGNSGIRG 3036 PGPPG+PG G+RG Sbjct: 890 PGPPGQPGFPGLRG 903 Score = 241 bits (616), Expect = 6e-63 Identities = 147/333 (44%), Positives = 164/333 (49%), Gaps = 42/333 (12%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SI 2801 Q G GP GP G PGAKG G G GA G PG G +G PGP GPPG G GL Sbjct: 367 QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGT 426 Query: 2802 PGEQGRQGMKGDAGEPGLPGRT------GTPGLPGPP--GPMGPPGDRGFTGKDGAMGPR 2853 PG+ G +G KG AGE G PG G PGLPGPP G G PG RG G G +G + Sbjct: 427 PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 486 Query: 2854 GPPGPPGSPGSP--------GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--------D 2897 G G PG PGSP GV GP G G PGD G PG GL G G +G Sbjct: 487 GDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSS 546 Query: 2898 IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARG 2957 + S + +A+ VC G L +P + G PG PG G+ G +G Sbjct: 547 LLSPGDINLLAKDVCNDCPPGPPG-----LPGLP----GFKGDKGVPGKPGREGTEGKKG 597 Query: 2958 EPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGPPGPQG-ES 3009 E GP G PG PG G QG GERG GE G++G G GP G PGPPG G Sbjct: 598 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 657 Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GPPG GS G GPPG G SG+ G PG G Sbjct: 658 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 690 Score = 228 bits (580), Expect = 9e-59 Identities = 142/356 (39%), Positives = 161/356 (45%), Gaps = 52/356 (14%) Query: 2724 PSRRDEGKCPAFPN--SCTCTQDSVGPPGPPGPAGGPGA------KGPRGERGISGAIGP 2775 P R E P P Q G PG G AG PGA +G +G++G G +G Sbjct: 252 PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 311 Query: 2776 PGPRGDIGPPGPQGPPGPQGPNGLS--------IPGEQGRQGMKGDAGEPGLPGRTGTPG 2827 PG +GD G G GP GP G G + +PGEQG +G KGD G PG PG G PG Sbjct: 312 PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 371 Query: 2828 LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG 2887 GP GP GPPG +G G GA G G PG PG G+PG +GP G G PG G PG G Sbjct: 372 ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 431 Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 2947 +GEKG G+ S + R PG PG P Sbjct: 432 ERGEKGAAGEEGSPGPV-------------------------------GPRGDPGAPGLP 460 Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007 GPPG G GEPG G PG PG G +G G G+PG G RG G G PGP GP G Sbjct: 461 GPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 519 Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRG--PPGPPGYCDSSQCASIPYNGQGYPG 3061 + G PGS G G PGP G G G+ PG C P G PG Sbjct: 520 DK--GSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG 573 Score = 228 bits (580), Expect = 9e-59 Identities = 162/401 (40%), Positives = 184/401 (45%), Gaps = 89/401 (22%) Query: 2747 GPPGPPGPAGGPGAKGP------RGERGISG---AIGPPGPRGDIGPPGPQGPP--GPQG 2795 GP GPPG G PG +G RGE+G +G + GP GPRGD G PG GPP G G Sbjct: 410 GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 469 Query: 2796 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLP-----GPPGPMGPPGD------RGF 2843 GL PG G G KGD G PG+PG G+ G P GPPGP GPPGD RG Sbjct: 470 EPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 529 Query: 2844 TGKDGAMGPRG------------------------PPGPPGSPGSPGVTGPSGKPGKPGD 2879 G G GP G PPGPPG PG PG G G PGKPG Sbjct: 530 PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 589 Query: 2880 HGR------------PGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQM----NRF 2923 G PGP G+ G +G +G+ + + Q + G M N Sbjct: 590 EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ-GHPGVPGFMGPPGNPG 648 Query: 2924 NQMLNQI-----PNDYQSSRNQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPG 2969 + I P Q S + GPPGP GP G G GE PGP G PG G Sbjct: 649 PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG 708 Query: 2970 TPGMQGPPGERGLPGEKGERG-TGSSGPR------GLPGPPG-PQGESRTGPPGSTGSRG 3021 PG+ GP G RG PG KG G +G+ GPR GLPG G P + TGP G G +G Sbjct: 709 EPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 768 Query: 3022 PPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ-GYPG 3061 P GPPG+ G+ G G PGP G Q S NG G PG Sbjct: 769 PRGPPGKNGSPGSPGEPGPSG--TPGQKGSKGENGSPGLPG 807 Score = 224 bits (572), Expect = 8e-58 Identities = 152/389 (39%), Positives = 185/389 (47%), Gaps = 76/389 (19%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS------ 2800 G G PG G PG +G +G++G G +G PG +GD G G GP GP G G + Sbjct: 283 GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH 342 Query: 2801 --IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA--------- 2849 +PGEQG +G KGD G PG PG G PG GP GP GPPG +G G GA Sbjct: 343 PRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA 402 Query: 2850 ---MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRA 2906 +G GP GPPGS G+PG+ G GK G+ G+ G G G G G RGD + + Sbjct: 403 PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP 462 Query: 2907 VAR-QVCEQLISGQM-------NRFNQMLNQIPNDYQSSRNQP-----GPPGPPGPP--- 2950 + + E + G + ++ IP SR P GPPGP GPP Sbjct: 463 PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGS-PGSRGDPGIGVAGPPGPSGPPGDK 521 Query: 2951 GSAGARGEP------GPGGR------------------------PGFPGTPGMQGPPGER 2980 GS G+RG P GP GR PG PG PG+ G G++ Sbjct: 522 GSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581 Query: 2981 GLPGEKGERGT----GSSGPRGLPGPP---GPQG-ESRTGPPGSTGSRGPPGPPGRPGNS 3032 G+PG+ G GT G +GP GLPGPP GPQG + G G G +G G PG PG Sbjct: 582 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641 Query: 3033 GIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G G PGPPG D A+ P QG PG Sbjct: 642 GPPGNPGPPG-ADGIAGAAGPPGIQGSPG 669 Score = 176 bits (447), Expect = 2e-43 Identities = 126/332 (37%), Positives = 148/332 (44%), Gaps = 53/332 (15%) Query: 2759 GAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPG 2818 G +GP +R + A + G G PG +G +GL G+ G++G+ GE G Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLP-----GKPGLRGEIGEQG 274 Query: 2819 LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG 2878 L GR G G G PG G PG RG G G G G PG G G G GP+G PG PG Sbjct: 275 LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 334 Query: 2879 ------DHGR-PGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931 H R PG G KGEKGD G E + G+ P Sbjct: 335 TTSLFTPHPRMPGEQGPKGEKGDPG-------------LPGEPGLQGRPGELGPQGPTGP 381 Query: 2932 NDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG- 2990 + G PG G PG+ G G PGP G PG G PG++G PG+ G GEKG G Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 441 Query: 2991 ---TGSSGPR---GLPGPPGPQGESRTGPPGSTGSRGPPGP---------PGRPGNSGIR 3035 G GPR G PG PGP G+ + G PG GS G PGP PG PG+ G R Sbjct: 442 EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSR 501 Query: 3036 GPP-----GPPGYCDSSQCASIPYNGQGYPGS 3062 G P GPPG S P +G PGS Sbjct: 502 GDPGIGVAGPPG-------PSGPPGDKGSPGS 526 Score = 108 bits (269), Expect = 1e-22 Identities = 59/128 (46%), Positives = 67/128 (52%), Gaps = 13/128 (10%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 PA+ S +Q GPPGPPG G PG GP GE G G G GP G IGP G +G G Sbjct: 936 PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 992 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 G G+ + GE G G+ G GEPG + G PG+PGP G GP G G Sbjct: 993 DPGAPGVGLRGEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGPAGHPGLP-------- 1043 Query: 2853 RGPPGPPG 2860 GPPGPPG Sbjct: 1044 -GPPGPPG 1050 Score = 101 bits (252), Expect = 1e-20 Identities = 89/275 (32%), Positives = 105/275 (38%), Gaps = 79/275 (28%) Query: 2813 DAGEPGLPGRTGTPGLPGPPGPMG--PPGDRGFTGKD--GAMGPRGPPGPPG-------- 2860 D G G GR T LP P P G TG + A+G +GP Sbjct: 182 DQGAQGACGRGNTSVLPSSVAPQCSMPKG----TGHEFSAALGTQGPADQRADARASCIL 237 Query: 2861 -SPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQ 2919 + +PG+ +G+PG+ G+ G PG GL RG+I Sbjct: 238 AAKTAPGLKQLNGEPGERGEDGLPGKPGL------RGEI--------------------- 270 Query: 2920 MNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE 2979 G G G PG G G PG G PG G G QG GE Sbjct: 271 ----------------------GEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE 308 Query: 2980 RGLPGEKGERGT-GSSGPRGLPGPPG--------PQGESRTGPPGSTGSRGPPGPPG--- 3027 GLPG KG+RG G +GP G PG PG P+ GP G G G PG PG Sbjct: 309 LGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 368 Query: 3028 RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 RPG G +GP GPPG P G PG+ Sbjct: 369 RPGELGPQGPTGPPGAKGQEGAHGAP-GAAGNPGA 402 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 259 bits (663), Expect = 2e-68 Identities = 147/341 (43%), Positives = 177/341 (51%), Gaps = 34/341 (9%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G PGPPG G PGA+G E G G G PGP G +GPPGP G PGP G + + + G++G Sbjct: 1261 GKPGPPGSTGRPGAEG---EPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRG 1317 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPP------------------GPMGPPGDRGFTGKDG 2848 G +G AG PG PG G PG PG P GP GP GD G G+ G Sbjct: 1318 ATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKG 1377 Query: 2849 AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGR---PGPS---GLKGEKGDRGDIASQN 2902 G +G G PG PG G GP G PG G+ G PGPS GL G G GD+ + + Sbjct: 1378 QAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYD 1437 Query: 2903 MMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962 ++ RQ ++ +M + + Q P + ++ +PGPPG G PG GA G P Sbjct: 1438 EIKRFIRQEIIKMFDERMAYYTSRM-QFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP--- 1493 Query: 2963 GRPGFPGTPGMQGPPGERGLPGEKGER---GTGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019 G PG G G QG PG RGLPG KGE+ G G +G GLPGPPGPQG G G+TG Sbjct: 1494 GLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGP 1553 Query: 3020 RGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP 3060 G G PG PG G G PG G+C+ S C Q YP Sbjct: 1554 MGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYP 1594 Score = 243 bits (619), Expect = 3e-63 Identities = 144/321 (44%), Positives = 163/321 (50%), Gaps = 49/321 (15%) Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 2782 +P +R E P S +GPPG PG G PG G +GERG++G G +G+ Sbjct: 1028 LPGQRGEEGPPGMRGS-PGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGL---TGDKGEP 1083 Query: 2783 GPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRG 2842 GPPG G PG GP GL PG +G +G G AGE G PG G+ GLPGPPGP GP G+RG Sbjct: 1084 GPPGQPGYPGATGPPGL--PGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERG 1141 Query: 2843 FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQN 2902 G G G +G G PG PG P GP G PGK G G PGP KG +G RG Sbjct: 1142 PQGNSGEKGDQGFQGQPGFPGPP---GPPGFPGKVGSPGPPGPQAEKGSEGIRG------ 1192 Query: 2903 MMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962 P+ S PGPPGPPG G AG G G Sbjct: 1193 ----------------------------PSGLPGS---PGPPGPPGIQGPAGLDGLDGKD 1221 Query: 2963 GRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRG 3021 G+PG G PG GPPG G PG KG+ G G GP+G G PGP G TG PG+ G G Sbjct: 1222 GKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGS--TGRPGAEGEPG 1279 Query: 3022 PPGPPGRPGNSGIRGPPGPPG 3042 GP GRPG G GPPGPPG Sbjct: 1280 AMGPQGRPGPPGHVGPPGPPG 1300 Score = 237 bits (605), Expect = 1e-61 Identities = 142/329 (43%), Positives = 158/329 (48%), Gaps = 74/329 (22%) Query: 2747 GPPGPPGPAGGPGAKGP------RGERGISGAIGP---PGPRGDIGPPGPQGPPGPQGPN 2797 G PGPPG G PGA GP +GERG +G+ G PGP G G PGP GP GP+G Sbjct: 1081 GEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGER 1140 Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 2857 G G G +G +G G+PG PG G PG PG G GPPG + G +G GP G PG Sbjct: 1141 GPQ--GNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPG 1198 Query: 2858 PPGSPGSPGVTGPS------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQV 2911 PG PG PG+ GP+ GK GKPG G PGP+G G G Sbjct: 1199 SPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMG------------------ 1240 Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGPPGSA---GARGEPGPG 2962 P ++ PG PGP PGPPGS GA GEPG Sbjct: 1241 -------------------PPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAM 1281 Query: 2963 GRPGFPGTPGMQGPPGERGLPGE--------KGERG-TGSSGPRGLPGPPGPQGESRTGP 3013 G G PG PG GPPG G PG KG+RG TG G GLPG PGP G GP Sbjct: 1282 GPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG--HPGP 1339 Query: 3014 PGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 PG G+ G G G PG G GPPGP G Sbjct: 1340 PGEPGTDGAAGKEGPPGKQGFYGPPGPKG 1368 Score = 231 bits (590), Expect = 6e-60 Identities = 143/341 (41%), Positives = 165/341 (48%), Gaps = 76/341 (22%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGE---------RGISGAIGPPGPRGDIGPPGPQGPPGPQ- 2794 S G PGPPGPAG G +GP+G +G G GPPGP G G G GPPGPQ Sbjct: 1124 SEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQA 1183 Query: 2795 --------GPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP------MGPPG 2839 GP+GL PG G G++G AG GL G+ G PGL G PGP MGPPG Sbjct: 1184 EKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPG 1243 Query: 2840 DRGFTGKDGAMGPRGPPGPPGSPGS---------PGVTGPSGKPGKPGDHGRPGPSGLKG 2890 +G TG G GP+G G PG PGS PG GP G+PG PG G PGP G G Sbjct: 1244 FKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPG 1303 Query: 2891 E--------KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPG 2942 KGDRG + + + GQ PG Sbjct: 1304 PAGISAVGLKGDRGATGERGLAG----------LPGQ------------------PGPPG 1335 Query: 2943 PPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGP 3002 PGPPG PG+ GA G+ GP G+ GF G PG +G PG G G+ GE+G G+PG Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRA-----GMPGG 1390 Query: 3003 PGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 PG G GPPG G RG PG PG G+ G+ G PG G Sbjct: 1391 PGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMG 1431 Score = 226 bits (577), Expect = 2e-58 Identities = 186/620 (30%), Positives = 246/620 (39%), Gaps = 174/620 (28%) Query: 2561 VNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLS 2620 V QPT + P GLP + ++L L T + ++Q+TD + PQ+ + + ++L Sbjct: 84 VTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLE 143 Query: 2621 FFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNI 2680 + G+ + F V LF +HK+ + V + +++DC + + + Sbjct: 144 LRAQGQDGDFVSCIF---PVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPM 200 Query: 2681 TTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDI----------PSRRD-- 2728 G+ LG L + K +F +Q I C P + CC+I +RRD Sbjct: 201 RPVGHVFLG-LDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDTQ 259 Query: 2729 -----------EGK------CPAFPNSCTCTQDSVG---------------------PP- 2749 EGK C P + G PP Sbjct: 260 SNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPC 319 Query: 2750 -----------GPPGPAGG------PGAKGPRGERGISG----AIGPPGP-RGDIGPPGP 2787 P GP GG PG G +GE+G G I P P + GP G Sbjct: 320 VHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGE 379 Query: 2788 QGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP---PGPMGPPGDRGF 2843 +G G GP+GL GE+G++G KGD G G+PG+ G G PG GP G GD GF Sbjct: 380 KGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGF 439 Query: 2844 TGKDGAMGPRGPPG---------------PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888 G +G G GPPG P G PG G G SG PGK G G+PG G+ Sbjct: 440 VGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGV 499 Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948 KGEKGD +VC L P +Q+ PG PGP G Sbjct: 500 KGEKGD-------------PCEVCPTL---------------PEGFQNFVGLPGKPGPKG 531 Query: 2949 PPGS-AGARGEPGPGGRPGFPGTP----------------------------GMQGPPGE 2979 PG ARG+PG G G G P G+ G PG Sbjct: 532 EPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGR 591 Query: 2980 RGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPP------------ 3026 G+PG KGE+G G +GP G PGPPGP GP G G++G P P Sbjct: 592 AGVPGLKGEKGNFGEAGPAGSPGPPGP-----VGPAGIKGAKGEPCEPCPALSNLQDGDV 646 Query: 3027 ---GRPGNSGIRGPPGPPGY 3043 PG SG +G PGPPG+ Sbjct: 647 RVVALPGPSGEKGEPGPPGF 666 Score = 223 bits (568), Expect = 2e-57 Identities = 152/410 (37%), Positives = 187/410 (45%), Gaps = 92/410 (22%) Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRGDIGP---------PGPQG 2789 + VG PG PG G PG +GP G +G+ G GPP GP+G+ G PGP+G Sbjct: 753 EGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG 812 Query: 2790 PPGPQ------------------GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 2831 PPGP GP G S+ G GR G +G G G PG G G G Sbjct: 813 PPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGE 872 Query: 2832 PGPMGPP--GDRGFTGKDGAMGP-RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888 PG P GD F+G GA G G PG G PG+ GP G PG PG G PG +GL Sbjct: 873 PGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGL 932 Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQM----------NRFNQMLNQIPN------ 2932 G+ G ++ S + + + + +C + GQ + +Q + +P Sbjct: 933 PGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ 992 Query: 2933 -------------DYQSSRNQP---GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP 2976 +S P G PG PGPPG G RGE GP G G PG PG GP Sbjct: 993 CFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGP 1052 Query: 2977 P------GERGLPGEKGERG-TGSSGPRGLPGPPGPQG-ESRTGPP---------GSTGS 3019 P G GLPG +GERG TG +G +G PGPPG G TGPP G TGS Sbjct: 1053 PGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGS 1112 Query: 3020 RGPPGPPGRPGNSGIRGPPGPPG-------YCDSSQCASIPYNGQ-GYPG 3061 G G PG PG+ G+ GPPGP G +S + + GQ G+PG Sbjct: 1113 AGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPG 1162 Score = 208 bits (529), Expect = 8e-53 Identities = 135/350 (38%), Positives = 169/350 (48%), Gaps = 51/350 (14%) Query: 2747 GPPGPPG-----PAGGPGAKGPRGERGISGAIGPPGPRGDIGP---PGPQGPPGPQGPNG 2798 G PGPPG P G PGA G G +G+ G GPPGP G+ G PG +G GP GP G Sbjct: 780 GEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG 839 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--GDRGFTGKDGAMGP-RGP 2855 S+ G GR G +G G G PG G G G PG P GD F+G GA G G Sbjct: 840 ASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGS 899 Query: 2856 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915 PG G PG+ GP G PG PG G PG +GL G+ G ++ S + + + + +C Sbjct: 900 SWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDC 959 Query: 2916 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG------------PPGSAGARGEPGPGG 2963 + GQ ++ + + G PG PG P + ARG+ G Sbjct: 960 VQGQRAHPGYLVEK------GEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGD 1013 Query: 2964 RPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPP 3023 PG G+PG+ GPPG LPG++GE G G RG PGPPGP GPPG G+ G P Sbjct: 1014 -PGCVGSPGLPGPPG---LPGQRGEEGP--PGMRGSPGPPGP-----IGPPGFPGAVGSP 1062 Query: 3024 GPPGRPGNSGIRG---------PPGPPGYCDSSQCASIP--YNGQGYPGS 3062 G PG G G+ G PPG PGY ++ +P +GY GS Sbjct: 1063 GLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGS 1112 Score = 207 bits (528), Expect = 1e-52 Identities = 138/383 (36%), Positives = 163/383 (42%), Gaps = 119/383 (31%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP---------------------- 2784 G PG PG AG PG KG +G G +G G PGP G +GP Sbjct: 584 GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643 Query: 2785 --------PGPQGPPGPQGPNGLSIPGEQGR------QGMKGDA---GEPGLPGRTGTPG 2827 PGP G G GP G +PG+QG+ +G KGDA G+PG PG TG PG Sbjct: 644 GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703 Query: 2828 LPGPPGPMGPPGDRG------------------FTGKDGAMGPRGPPGP-----PGSPGS 2864 L G PG GP G +G G+ G GP+G GP PG PG Sbjct: 704 LSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQ 763 Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924 PG+ G G PG G G PGP G +G +G +G+ + + Sbjct: 764 PGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGL--------------------- 801 Query: 2925 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG--MQGPPGERGL 2982 + PGP GPPGP G GA+G PG G G G PG + GPPG G Sbjct: 802 ----------PGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQ 851 Query: 2983 PGEKGERGT-GSSGPRGLPGPPG-----PQGES-----------------RTGPPGSTGS 3019 G+ G RGT G GPRG G PG QG+ + GP G G Sbjct: 852 QGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911 Query: 3020 RGPPGPPGRPGNSGIRGPPGPPG 3042 GPPGPPG PG G+ G G PG Sbjct: 912 PGPPGPPGVPGLQGVPGNNGLPG 934 Score = 207 bits (526), Expect = 2e-52 Identities = 142/391 (36%), Positives = 171/391 (43%), Gaps = 97/391 (24%) Query: 2742 TQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI----GPPGPQGPPGPQGPN 2797 T + G PG G G G GP+GE+G G P +G + G PG GP G QGP Sbjct: 695 TPGTTGRPGLSGEPGVQGPAGPKGEKG-DGCTACPSLQGTVTDMAGRPGQPGPKGEQGPE 753 Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP--GPPGPMGPPGDRGFTGKDGAMGPRGP 2855 G+ PG+ G+ G+ G G PGL G G PG P G GP G PG G G G GPRGP Sbjct: 754 GVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGP 813 Query: 2856 PGP------PGSPGSPGVTGP--------SGKPGKPGDHGRPGPSGLKGEKGDRGDIASQ 2901 PGP GSPG G TGP SG PG+ G G+ G G GEKG RG+ Sbjct: 814 PGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEP 873 Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961 ++ + + SG + P + S QPGP GPPG P G PGP Sbjct: 874 GECSCPSQG--DLIFSG--------MPGAPGLWMGSSWQPGPQGPPGIP------GPPGP 917 Query: 2962 GGRPGFPGTPGMQGPPGERGLPGE-------------------KGERG-------TGSSG 2995 G PG G PG G PG+ GL E +G+R G G Sbjct: 918 PGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKG 977 Query: 2996 PRGLPGPPG------------------PQGESRTGPPGSTGSRGPPGPPGRPGN------ 3031 +G+PG PG +G++ G PG GS G PGPPG PG Sbjct: 978 DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037 Query: 3032 SGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 G+RG PGPPG P G+PG+ Sbjct: 1038 PGMRGSPGPPG----------PIGPPGFPGA 1058 Score = 147 bits (371), Expect = 2e-34 Identities = 104/285 (36%), Positives = 115/285 (40%), Gaps = 106/285 (37%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802 Q GPPGP G G G KG GE+G +G G PG G +GP GP GP Sbjct: 1358 QGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGP------------ 1405 Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG-------------------------- 2836 G+ G PG PG +G+PGLPG PG MG Sbjct: 1406 --------AGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAY 1457 Query: 2837 -------------PPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP 2883 PG G GKDGA G PG PGSPG PG G G+ G PG G P Sbjct: 1458 YTSRMQFPMEMAAAPGRPGPPGKDGA---PGRPGAPGSPGLPGQIGREGRQGLPGVRGLP 1514 Query: 2884 GPSGLKGEKGDRG-DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPG 2942 G KGEKGD G IA +N + PG Sbjct: 1515 ---GTKGEKGDIGIGIAGENGL------------------------------------PG 1535 Query: 2943 PPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKG 2987 PPGP GPPG G G GP G+ G PG P GPPG G PG+ G Sbjct: 1536 PPGPQGPPG-YGKMGATGPMGQQGIPGIP---GPPGPMGQPGKAG 1576 Score = 85.5 bits (210), Expect = 7e-16 Identities = 57/135 (42%), Positives = 61/135 (45%), Gaps = 22/135 (16%) Query: 2735 FPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ 2794 FP GPPG G G PGA G PG G IG G QG PG + Sbjct: 1464 FPMEMAAAPGRPGPPGKDGAPGRPGAP------------GSPGLPGQIGREGRQGLPGVR 1511 Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854 G +PG +G KGD G G+ G G PG PGP GP G G G TG G G G Sbjct: 1512 G-----LPGTKGE---KGDIG-IGIAGENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPG 1561 Query: 2855 PPGPPGSPGSPGVTG 2869 PGPPG G PG G Sbjct: 1562 IPGPPGPMGQPGKAG 1576 Score = 72.0 bits (175), Expect = 8e-12 Identities = 53/149 (35%), Positives = 66/149 (44%), Gaps = 21/149 (14%) Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP---- 2983 ++ P +R+ P GP G G RG PGP PG G G +G R P Sbjct: 314 DECPPCVHGARDSNVTLAPSGPKGGKGERGLPGP---PGSKGEKGARGNDCVRISPDAPL 370 Query: 2984 ----GEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGI---- 3034 G KGE+G +G+ GP GLPG G +G+ G G G +G PG PGR G G Sbjct: 371 QCAEGPKGEKGESGALGPSGLPGSTGEKGQK--GEKGDGGIKGVPGKPGRDGRPGEICVI 428 Query: 3035 --RGPPGPPGYCDSSQCASIPYNGQGYPG 3061 +G G PG+ A P G PG Sbjct: 429 GPKGQKGDPGFVGPEGLAGEP-GPPGLPG 456 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 259 bits (662), Expect = 3e-68 Identities = 155/346 (44%), Positives = 175/346 (50%), Gaps = 40/346 (11%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--- 2789 P P T GPPGPPG G PG G RGE G G GPPGP G +GP GP G Sbjct: 950 PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009 Query: 2790 ---------PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 2840 PPGP G GL PG G++G KGD G GLPG+ G PGL G PG G PG Sbjct: 1010 PMGERGHPGPPGPPGEQGL--PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1067 Query: 2841 RGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLK---GEKGD 2894 G G G GP GPPGP GSPG G GP G PG+PG G PGP+G K GEKG Sbjct: 1068 VGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP 1127 Query: 2895 RGDIASQNMMRAV-----ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP 2949 +G + V A V G + + + + PGP GP GP Sbjct: 1128 QGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP 1187 Query: 2950 ---PGSAGARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGP 2996 PG +GA GEPGP G+ G G PG GP G +GLPG GE+G TG G Sbjct: 1188 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247 Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G PGPPGP+G S G PG+ G +GPPG G PG G +G PG G Sbjct: 1248 MGPPGPPGPRGPS--GAPGADGPQGPPGGIGNPGAVGEKGEPGEAG 1291 Score = 256 bits (653), Expect = 3e-67 Identities = 156/377 (41%), Positives = 174/377 (46%), Gaps = 92/377 (24%) Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790 K P P Q VG PGP GP G PG G +GE G G G G +G+ GPPGP GP Sbjct: 1125 KGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP 1184 Query: 2791 ------PGPQGPNGLSIP-GEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGP------ 2834 PGP G +G P G+QG G KGD G PG PG G GLPGPPG Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244 Query: 2835 ---MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891 MGPPG G G GA G GP GPPG G+PG G G+PG+ G+ G PG G G Sbjct: 1245 VGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGP 1304 Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951 KG+RG+ A GPPGP GPPG Sbjct: 1305 KGERGEKGESGPSGAA----------------------------------GPPGPKGPPG 1330 Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG 3007 G +G PGP G PG PG PG GP G+ G PG+KG+ G TGS GP G PGP GP G Sbjct: 1331 DDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390 Query: 3008 E----------------------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCD 3045 + GPPG TG GP G PG+PG G+RG PGP G Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVG--- 1447 Query: 3046 SSQCASIPYNGQGYPGS 3062 QG PGS Sbjct: 1448 ----------EQGLPGS 1454 Score = 255 bits (651), Expect = 5e-67 Identities = 155/352 (44%), Positives = 173/352 (49%), Gaps = 59/352 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP-NGLSIPGEQ 2805 GPPGP G G PG G +GE G G +GPPGP G GP G G GPQGP G+ PG Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281 Query: 2806 GRQGMKGDAGEPGLPGRTGTPG---------------LPGPPGPMGPPGDRGFTGKDGAM 2850 G +G G+AGEPGLPG G PG GPPGP GPPGD G G G + Sbjct: 1282 GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341 Query: 2851 GPRGPPGPPGSPG---------------------SPGVTG---PSGKPGKPGDHGRPGPS 2886 G G PGPPG PG SPG TG PSG PGK G G GP Sbjct: 1342 GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPE 1401 Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946 G +GEKG +G+ + + Q G+ P Q PGP GP Sbjct: 1402 GRQGEKGAKGEAGLEGPPGKTG-PIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460 Query: 2947 PGP---PGSAGARGEPGPGGRPGFPGTPGMQGPPGE------RGLPGEKGERG------- 2990 PGP PG G +G+ GP G G PG G+ GPPGE RGLPG +G G Sbjct: 1461 PGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGI 1520 Query: 2991 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 TG SGP G PGPPG G GP G+ GS GP GP G G+ G GPPGPPG Sbjct: 1521 TGPSGPIGPPGPPGLPGPP--GPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 254 bits (648), Expect = 1e-66 Identities = 148/330 (44%), Positives = 168/330 (50%), Gaps = 57/330 (17%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGD------IGPPG 2786 P FP + + G PG PGP G G GPRGERG G G PGP+G+ GPPG Sbjct: 888 PGFPGA-NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPG 946 Query: 2787 PQGPPGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 2845 +GP GPQGP G P G G G G G PG G TG G GPPGP G G +G TG Sbjct: 947 ERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTG 1006 Query: 2846 KDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD------HGRPGPSGLKGEKGDRGDIA 2899 + G MG RG PGPPG PG G+ G +GK G GD G+ GP GL+G GDRG Sbjct: 1007 ETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRG--- 1063 Query: 2900 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 2959 + G + N+ GPPGPPGP GS G RG Sbjct: 1064 ----------------LPGPVGALGLKGNE------------GPPGPPGPAGSPGERGPA 1095 Query: 2960 GPGGRPGFPGTPGMQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTG 3012 G G G PG PG QGPP GE+G PGEKG +G G GP GLPGP GP G Sbjct: 1096 GAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP-----VG 1150 Query: 3013 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 PPG G +G G PG+ G+ G +G GPPG Sbjct: 1151 PPGEDGDKGEIGEPGQKGSKGDKGEQGPPG 1180 Score = 251 bits (641), Expect = 8e-66 Identities = 150/347 (43%), Positives = 167/347 (48%), Gaps = 36/347 (10%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G PGPPGP G G GP GE+G +G +G GP G GP GP G PG GP G PG G Sbjct: 1219 GFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGGIG 1276 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866 G G+ GEPG G G PG GPPGP G G++G +G GA GP GP GPPG G G Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336 Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926 GP G PG PG G PGP+G G GD+GD + E SG + Sbjct: 1337 SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG-PTGEPGPSGPPGKRGPP 1395 Query: 2927 LNQIPNDYQSSRNQP---------------GPPGPPGPPGSAGARGEPGPGGRPGFPGTP 2971 P Q + GP G PG PG G RG PGP G G PG+P Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP 1455 Query: 2972 GMQGPPGER---GLPGEKGERG----TGSSGPRGLPGPPGPQGE----------SRTGPP 3014 G GPPG GLPG KG+ G G G GL GPPG QGE +GP Sbjct: 1456 GPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK 1515 Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G G GP GP G PG G+ GPPGP G SS P G+PG Sbjct: 1516 GEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG-PKGEAGHPG 1561 Score = 242 bits (618), Expect = 4e-63 Identities = 148/348 (42%), Positives = 173/348 (49%), Gaps = 50/348 (14%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGA---IGPPGPRGDIGPPGPQGPPGPQGPNGLS--- 2800 GP GP G G PG GP G G+ G +GP GPRG GPPGP G PG +G G Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618 Query: 2801 -IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------ 2853 +PG+ G +G +G G GLPG G G PGP GP GPPGD G G DG +GPR Sbjct: 619 GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678 Query: 2854 ------GPPGPPGSPGSPGVTGPSGKPGKPGD---HGRPGPSGLKGEKGDRGDIASQNMM 2904 GP GPPG PG PGVTG G+PG G+ G PGP G +G G +G Q + Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAI 738 Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR 2964 + G + + L +P + PG PG GPPG G +G PGP G Sbjct: 739 GPPGEK-------GPLGK--PGLPGMP----GADGPPGHPGKEGPPGEKGGQGPPGPQGP 785 Query: 2965 PGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SRTGP 3013 G+PG G++G G RGL G KGE+G G G RG GPPGP+GE GP Sbjct: 786 IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP 845 Query: 3014 PGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G G G PGP G PG G G PG PGY P G+PG Sbjct: 846 KGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG----PKGSIGFPG 889 Score = 239 bits (611), Expect = 2e-62 Identities = 137/315 (43%), Positives = 158/315 (50%), Gaps = 46/315 (14%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNGLSIPGE 2804 +GP GPPGP G P G++G G PGP+G++GP G GPPG QG P +PG Sbjct: 684 LGPKGPPGPPGPP---------GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGP 734 Query: 2805 QGR---QGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGS 2861 QG G KG G+PGLPG G G PG PG GPPG++G G G GP G PGP G Sbjct: 735 QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794 Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921 G+ G+ G G G+ G+ G PG G G KGDRG+I G Sbjct: 795 KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEI-------------------GPPG 835 Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------GPGGRPGFPGTPGMQG 2975 + + P PGP GPPG G G G P GP G GFPG PG G Sbjct: 836 PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895 Query: 2976 PPGERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPG 3027 G RG PG+ G RG G GPRG+ G PGP+G S GP G G RGP GP G Sbjct: 896 EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQG 955 Query: 3028 RPGNSGIRGPPGPPG 3042 G G +GPPGPPG Sbjct: 956 PTGFPGPKGPPGPPG 970 Score = 239 bits (610), Expect = 3e-62 Identities = 141/328 (42%), Positives = 165/328 (50%), Gaps = 32/328 (9%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP------------PGPQGPPGPQ 2794 G G G G PG KG G +G G IGPPGPRG+ GP PGP GPPG + Sbjct: 805 GTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK 864 Query: 2795 GPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853 G G+ +PG GRQG KG G PG PG G G G PG GP G RG TG G GPR Sbjct: 865 GKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPR 924 Query: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR--QV 2911 G G PG G+ G GP+G PG+ G +G GP+G G KG G + + + Sbjct: 925 GITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984 Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP---------GSAGARGEPGPG 2962 Q +G + Q P + G PGPPGPP G G +G+PGP Sbjct: 985 GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044 Query: 2963 GRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE----SRTGP---P 3014 G PG G PG++G PG+RGLPG G G G+ GP G PGP G GE GP P Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104 Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G G +GPPGP G G G +GP GP G Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAG 1132 Score = 235 bits (600), Expect = 4e-61 Identities = 147/362 (40%), Positives = 167/362 (46%), Gaps = 74/362 (20%) Query: 2743 QDSVGPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799 Q ++GPPG GP G PG G G G G GPPG +G GPPGPQGP G GP G+ Sbjct: 735 QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794 Query: 2800 -------------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP--------- 2831 PG +G G+KGD GE G PG G G GP Sbjct: 795 KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854 Query: 2832 PGPMGPPGDR------GFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885 PGP+GPPG++ G G G GP+G G PG PG+ G G G PGKPG G+ GP Sbjct: 855 PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914 Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPG 2945 +G +GE+G RG + + + SG + PN Q PGP G Sbjct: 915 TGPRGERGPRG----------ITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKG 964 Query: 2946 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGP 3005 PPGPPG G G PG G GF G G GPPG G G GE TG G RG PGPPGP Sbjct: 965 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE--TGPMGERGHPGPPGP 1022 Query: 3006 QGE----------------------SRTGPP---GSTGSRGPPGPPGRPGNSGIRGPPGP 3040 GE + GPP G G RG PGP G G G GPPGP Sbjct: 1023 PGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP 1082 Query: 3041 PG 3042 PG Sbjct: 1083 PG 1084 Score = 233 bits (594), Expect = 2e-60 Identities = 151/354 (42%), Positives = 167/354 (47%), Gaps = 62/354 (17%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISG---AIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800 G PGP G G PG KGP G+ G+ G A GPPG G GPPG QGPPGPQGP G Sbjct: 730 GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789 Query: 2801 IP-------GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853 P G +G +G KG+ GE G PG G G+ G G +GPPG RG G +G G Sbjct: 790 GPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRG 849 Query: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS---------GLKGEKGDRGDIASQNMM 2904 GP G PG G PG G G PG PG GR GP G GEKG RG Sbjct: 850 GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG-------- 901 Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGPPGSAGARGE 2958 G+ Q P + R G PGP GP G G RG Sbjct: 902 -----------TPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950 Query: 2959 PGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP---GPQGES-RTGP 3013 GP G GFPG G GPPG+ GLPG G+RG TG G G PGPP GPQG + TGP Sbjct: 951 NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP 1010 Query: 3014 PGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G G GPPGPPG G G +G PGP G P +G+PG Sbjct: 1011 MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDG----PPGLRGFPG 1060 Score = 202 bits (515), Expect = 3e-51 Identities = 134/346 (38%), Positives = 153/346 (44%), Gaps = 74/346 (21%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-------- 2798 GPPGP GPAG PG P G G +G +G PG RG G PG G G GP G Sbjct: 469 GPPGPEGPAGLPG---PPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFR 525 Query: 2799 -----------------------------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP 2829 L++ G G G+ G G G PG G G P Sbjct: 526 FGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEP 585 Query: 2830 GPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGP---------SGKPGKPGDH 2880 G GP GP G +G G G G RG G G+ G PG TGP +G PG+ G Sbjct: 586 GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645 Query: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ 2940 G PGPSG G GD G+ R +V + + G+ + Sbjct: 646 GDPGPSGPPGPPGDDGE-------RGDDGEVGPRGLPGEPGP------------RGLLGP 686 Query: 2941 PGPPGPPGPPGSAGARGEPGPGGR---PGFPGTPGMQGPPGERGLPGEKGERG-TGSSGP 2996 GPPGPPGPPG G G+PGP G G PG PG QG PG +GLPG +G G G GP Sbjct: 687 KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP 746 Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G PG PG G GPPG G GPPG G G G +GP G PG Sbjct: 747 LGKPGLPGMPGAD--GPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790 Score = 199 bits (506), Expect = 3e-50 Identities = 116/245 (47%), Positives = 131/245 (53%), Gaps = 33/245 (13%) Query: 2747 GPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 GPPG PGPAG PG KG GE G +G+ GP G G GPPG +GPPGP GP G Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEG----- 1402 Query: 2804 EQGRQGMKGDAGEPGLPGRTG------TPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 2857 QG +G KG+AG G PG+TG PG PGP G G PG G G G+ GP GPPG Sbjct: 1403 RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462 Query: 2858 PPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914 P G PG PG+ +GP G+ G PG G GP G +GEKGDRG Q EQ Sbjct: 1463 PMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKG----EQ 1518 Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 2974 I+G P+ PG PGPPGP G+ G+ G GP G G PG PG Sbjct: 1519 GITG------------PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPP 1566 Query: 2975 GPPGE 2979 GPPGE Sbjct: 1567 GPPGE 1571 Score = 175 bits (443), Expect = 7e-43 Identities = 138/395 (34%), Positives = 160/395 (40%), Gaps = 95/395 (24%) Query: 2728 DEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGA--------IGPPGPR 2779 D G P S T +S P PPG G +G E I P Sbjct: 369 DPGAGAEIPTSTADTSNSSNPAPPPGE-GADDLEGEFTEETIRNLDENYYDPYYDPTSSP 427 Query: 2780 GDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAG--EPGLPGRTGTPGLPGPPGPMGP 2837 +IGP G P Q I G +G +G KG+ EPG+ + GPPGP GP Sbjct: 428 SEIGP----GMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML-------IEGPPGPEGP 476 Query: 2838 PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG----LKGEKG 2893 G GP G GP G G PG GP G+PG PG G PGP G L G Sbjct: 477 A---------GLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527 Query: 2894 DRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI------PNDYQSSRNQPGPPGPP 2947 GD S+ M +S Q ++ +L Q P +PGP GPP Sbjct: 528 GGGDAGSKGPM-----------VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP 576 Query: 2948 ------------GPPGSAGARGEPGPGGRP---------GFPGTPGMQGPPGER------ 2980 GP G G +G PGP G+P G G PG GP G+R Sbjct: 577 GSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLA 636 Query: 2981 GLPGEKGERGTGSSGPRGLPGPPGPQGE-------------SRTGPPGSTGSRGPPGPPG 3027 GLPGEKG R G GP G PGPPG GE GP G G +GPPGPPG Sbjct: 637 GLPGEKGHR--GDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPG 694 Query: 3028 RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 PG +G+ G PGP G Q P QG PG+ Sbjct: 695 PPGVTGMDGQPGPKGNV-GPQGEPGPPGQQGNPGA 728 Score = 151 bits (381), Expect = 1e-35 Identities = 94/244 (38%), Positives = 104/244 (42%), Gaps = 86/244 (35%) Query: 2745 SVGPPGPPGPAGGPGAKGP---------RGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 2795 S GP G PGP+G PG +GP +GE+G G G GP G GP GPQG PG G Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435 Query: 2796 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPG---------------------PPG 2833 P+GL IPG G QG+ G G G PG G PGLPG PPG Sbjct: 1436 PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPG 1495 Query: 2834 PMGPPGDRGFTGKDGAMGPRG------PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG 2887 G GDRG G G+ GP+G P GP G PG PG+ GP PG G G GP+G Sbjct: 1496 EQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGP---PGPKGAKGSSGPTG 1552 Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 2947 KGE G PGPPGPP Sbjct: 1553 PKGEAG----------------------------------------------HPGPPGPP 1566 Query: 2948 GPPG 2951 GPPG Sbjct: 1567 GPPG 1570 Score = 104 bits (259), Expect = 2e-21 Identities = 61/128 (47%), Positives = 69/128 (53%), Gaps = 20/128 (15%) Query: 2747 GPPGPPGPAGGPGAKG---PRGERG---ISGAIGPPGP---RGDIGPPGPQGPPGPQGPN 2797 GPPGP GP G PG KG P+GE+G + G IGPPG +GD G PGPQG GP+G Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518 Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 2857 G++ G G G G G PG PG G G GP GP G+ G GP GPPG Sbjct: 1519 GIT--GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGP---------KGEAGHPGPPGPPG 1567 Query: 2858 PPGSPGSP 2865 PPG P Sbjct: 1568 PPGEVIQP 1575 Score = 90.5 bits (223), Expect = 2e-17 Identities = 46/95 (48%), Positives = 50/95 (52%), Gaps = 14/95 (14%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQ 2805 +GPPG G G G GP+G G G G GP G IGPPGP G PGP GP G G Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAK--GSS 1548 Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 2840 G G KG+AG PGPPGP GPPG+ Sbjct: 1549 GPTGPKGEAGH------------PGPPGPPGPPGE 1571 Score = 73.2 bits (178), Expect = 4e-12 Identities = 34/74 (45%), Positives = 41/74 (55%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802 Q GP GP GP G PG GP G +G G+ GP GP+G+ G PGP GPPGP G +P Sbjct: 1518 QGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577 Query: 2803 GEQGRQGMKGDAGE 2816 + R DA + Sbjct: 1578 IQASRTRRNIDASQ 1591 Score = 33.9 bits (76), Expect = 2.5 Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 7/146 (4%) Query: 2522 KMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHP-NGLPPSYTII 2580 K+L+ +NL + + + S AYR+ K+A ++ PT L+P + P ++I+ Sbjct: 44 KVLDFHNLPDGITKTTGFCATRRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSIL 103 Query: 2581 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV 2640 + + S F + I + Q+G+ ++ F +D G+ + Sbjct: 104 TTVK--AKKGSQAFLV-SIYNEQGIQQIGL---ELGRSPVFLYEDHTGKPGPEDYPLFRG 157 Query: 2641 KTLFYGSFHKVHIVVTSKSVKIYIDC 2666 L G +H++ + V K+V + +DC Sbjct: 158 INLSDGKWHRIALSVHKKNVTLILDC 183 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 254 bits (650), Expect = 7e-67 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 2794 GPPGPPG G PG G RGE G G GPPGP G +GP GP G PPGP Sbjct: 946 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 1005 Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854 G GL PG G++G KGD G G+ G+ G GL G PG G PG +G G G GP+G Sbjct: 1006 GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1063 Query: 2855 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 2907 PPGP GSP GS G GP G PG+PG G PGP+G K GEKG +G + V Sbjct: 1064 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1123 Query: 2908 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 2954 A E G++ Q + + + GPPGPP G PG AG Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1177 Query: 2955 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004 GEPGP G+ G G PG GP G +GLPG GE+G G GP G PGPPG Sbjct: 1178 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237 Query: 3005 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 P+G + GPPGS GS G G G PG +G GPPG G Sbjct: 1238 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282 Score = 249 bits (635), Expect = 4e-65 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%) Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790 K P P Q VG PGP GPAG PG G +GE G G G G +G+ GPPGP G Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166 Query: 2791 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 2833 GP G G++ PG +G+QGM G G+ PG PG G GLPGPPG Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1226 Query: 2834 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891 PMGPPG G G G G GP GPPGS GS G G G+PG+ G+ G PG +G+ G Sbjct: 1227 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1286 Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951 KG+RG+ A +G + P PG PGPPG PG Sbjct: 1287 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336 Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 3009 AG G G G G PG PG GP GE G PG G+RG G++G G G G +GE+ Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1396 Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GPPG TG GP GP G+PG G+RG PGP G Sbjct: 1397 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1429 Score = 242 bits (618), Expect = 4e-63 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805 GPPGP G G PG G +GE G G +GPPGP G GP GP G GPQGP G + G Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1263 Query: 2806 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 2850 G +G G+AG PG PG G PG GPPG GPPGD G G G + Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323 Query: 2851 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 2888 G G PGPPG PG PG GPSG+ G PG G+ GP G Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383 Query: 2889 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 2941 +GEKG +G+ ++ V Q +G+ + L IP + Q Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1440 Query: 2942 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 2997 GPPGP GPPG G +G+PG G G PG G+ GPPGE+G G++G GT G+ G Sbjct: 1441 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1500 Query: 2998 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G+PGP GP G GP G G++G GP G+ G+SG+ GPPG PG Sbjct: 1501 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Score = 239 bits (611), Expect = 2e-62 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%) Query: 2746 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 2798 +GP G PG AG G GPR G+ G++G GPPGP+G++GP G GPPG QG P Sbjct: 651 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 2858 +PG QG G G+ G G PG G PG GPP G PG G +G+ GA+GP GP GP Sbjct: 711 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 767 Query: 2859 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 2918 G PG GV G G G G G G G G KGD G + G Sbjct: 768 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 808 Query: 2919 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 2978 Q+ + + + + + GP G PGP G AG +G+ G PG PG PG QGP G Sbjct: 809 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 865 Query: 2979 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037 G PG G G G RG+ G PGP+G+ TGP GS G+RGP G PG G SG GP Sbjct: 866 STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923 Query: 3038 PGPPGYCDSSQCASIPYNGQGYPG 3061 PGPPG + P G+PG Sbjct: 924 PGPPG----ERGPQGPQGPVGFPG 943 Score = 239 bits (611), Expect = 2e-62 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P P + G PGP G +GG G GP GERG P GP+G +G PGP+GPPG Sbjct: 896 PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 949 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 P PG+ G G G GE G G+TG PG G GP GP G+ G G+ G GP Sbjct: 950 P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001 Query: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 2912 GPPG G PG+ G G G PG G G+ GP+GL+G G+RG +Q Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1052 Query: 2913 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 2972 + GP GPPGP GS G RG G G G PG PG Sbjct: 1053 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1090 Query: 2973 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 3025 QGPP GE+G PGEKG +G G GP GLPGP GP G G G G G PG Sbjct: 1091 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1148 Query: 3026 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G G+ G GPPGPPG I G G PG Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1183 Score = 239 bits (609), Expect = 4e-62 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%) Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 2796 GPPGP PGP GGPG+ G +GE SG GP GPRG GPPGP G PG +G Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597 Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856 G +PGE G +G +G G PGLPG G G GP GP GPPGD G G+DG +GPRG P Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 657 Query: 2857 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 GP G+PG+PG G +G G PG G GP G G G +G+ Q Sbjct: 658 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 712 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 2961 + G + P PG GPPG PG G GE PGP Sbjct: 713 --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 764 Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 3010 G G+PG G++G G RGL G KGE+G G G RG G GP+GE Sbjct: 765 QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 824 Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GP G G G PGP G+ G G G PG PGY P G+PG Sbjct: 825 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 871 Score = 227 bits (579), Expect = 1e-58 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 2777 ++GPPGP GP G PG +G +G G+ G +G G Sbjct: 758 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 817 Query: 2778 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 2822 PRG+ GP GP+G GP G G S +PG GRQG KG G PG PG Sbjct: 818 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 877 Query: 2823 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 2869 G PG G GP GP G RG G G GP+ GPPGPPG G G G Sbjct: 878 EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 937 Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 2927 P G PG G G PG GL G G RG+ Q V Q +G+ + Sbjct: 938 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 995 Query: 2928 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 2981 R PGPPGPPG PG+A GA+G+PGP G G G G++G PGERG Sbjct: 996 ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 1045 Query: 2982 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 3033 LPG +G G G GP+G PGP PG +G + T G PG G +GPPGP G G G Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105 Query: 3034 IRGPPGPPG 3042 +GP GP G Sbjct: 1106 EKGPQGPAG 1114 Score = 224 bits (571), Expect = 1e-57 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 2791 GPPGP G G G GP G++G G G PGP+G IGPPG PQG PP Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 744 Query: 2792 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835 GP GP G + PG +G +G G G G G G G PG G M Sbjct: 745 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 804 Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895 G GDRG G+ G G GP GP G G G GPSG+ G+ G G PG G G +G + Sbjct: 805 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864 Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 2949 G A + ++G+ Q P + +R G PGP GP Sbjct: 865 GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923 Query: 2950 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 3002 PG G RG GP G GFPG G GPPG+ GLPG G+RG TG GP G+ GP Sbjct: 924 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983 Query: 3003 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 3056 GP GE TGP G G GPPGPPG G G +G PGP G A + Sbjct: 984 QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 1037 Query: 3057 QGYPG 3061 +G+PG Sbjct: 1038 RGFPG 1042 Score = 210 bits (534), Expect = 2e-53 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%) Query: 2747 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 2794 GPPGP GPAG PG +GP G G G GPPG G G G GPPG Sbjct: 454 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 2795 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844 G G +I + Q R ++G G GL GR G G PG G G GD G Sbjct: 514 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 573 Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 2901 G G GP GP G PG G PG G G PG+P GD G G GL G+KG RG+ Q Sbjct: 574 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 633 Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961 P R + G GP G PG AG RG GP Sbjct: 634 GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 668 Query: 2962 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 3007 G PG PG PGM GPPG +G G +GE G G+ GP+GLPGP GP G Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728 Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 + + G G G+ GPPG PG+ G SG +G GPPG P GYPG Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 772 Score = 201 bits (512), Expect = 7e-51 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GPPG PGPAG G G +GE G G GPPGP G+ GPPGP G GP G G G QG Sbjct: 1330 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1387 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 2863 +G KG+AG G PG+TG G GP G GP G RG G+ G G G GPPG G Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447 Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923 PG+ G G PG G+ G PG GL G G++G+ Sbjct: 1448 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1481 Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983 + R PG G PG G G G GP G PG PG PG QGP G +G Sbjct: 1482 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530 Query: 2984 GEKGERG-TGSSGPRGLPGPPG 3004 G G++G +G GP G PGPPG Sbjct: 1531 GPAGQKGDSGLPGPPGSPGPPG 1552 Score = 177 bits (449), Expect = 1e-43 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%) Query: 2748 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 2799 P PP GPG A+ E I+G A G G +G+ + PG +GPPGP GP G+ Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859 G PGL GP GP G PGDRG G+ G G G PGPP Sbjct: 465 M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 501 Query: 2860 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 2886 G+ GS G T GP G G+PG G PG S Sbjct: 502 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 561 Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946 G KGE GD G + + G + + R PG PG Sbjct: 562 GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 608 Query: 2947 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 2994 PG PG G RGE GP G PG PG GM+G GE RGLPGE G RG Sbjct: 609 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 666 Query: 2995 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 3042 GPRG PG PG G + GPPG G+ GP PGPPG+ GN G +G PGP G Sbjct: 667 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718 Score = 137 bits (346), Expect = 1e-31 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 2798 GP G PGP G G GP GE+G+ GA G PPGP G G PG +G PG +G G Sbjct: 1411 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1470 Query: 2799 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856 + PGEQG +G +G G G PG G G+PGP GP+GPPG G G G G +G Sbjct: 1471 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530 Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885 GP G G G+ GP G PG PG+ +P P Sbjct: 1531 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559 Score = 130 bits (327), Expect = 2e-29 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 + G GPPGP G PG G +G+ G G G PG G IGPPG QG G +G +PG Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1490 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 QG G KGD G PG G G PG PG PGP GP G++G TG G G G PGPPGSPG Sbjct: 1491 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1550 Query: 2865 PG 2866 PG Sbjct: 1551 PG 1552 Score = 90.5 bits (223), Expect = 2e-17 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 2778 +GPPG PG G PG+KG +G G+ G IGPPG P Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1505 Query: 2779 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 2838 G +GPPGP G PGPQGP G G G G KGD+G P G PG PGPPG + P Sbjct: 1506 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1557 Score = 58.2 bits (139), Expect = 1e-07 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%) Query: 2933 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 2976 +Y+ ++P PP PG P GA GE G G P PGM +GP Sbjct: 397 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 455 Query: 2977 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 3036 PG +GP G+ GPPG QG TGPPG G R G PG G+ G Sbjct: 456 PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 493 Query: 3037 PPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG + Y G G G Sbjct: 494 ADGLPGPPGTMLMLPFRYGGDGSKG 518 Score = 47.0 bits (110), Expect = 3e-04 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%) Query: 2536 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 2588 S +G+S +G S S +AYR+ K A ++ PT L P G P +LF + P+ Sbjct: 50 SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108 Query: 2589 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 2648 F + I + Q+GV ++ F +D G+ + + G + Sbjct: 109 KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 2649 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 2706 H+V I V K+V + +DC + K D E + T+G + G + E IQ F Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223 Query: 2707 DIVCSP 2712 I P Sbjct: 224 LITGDP 229 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 254 bits (650), Expect = 7e-67 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 2794 GPPGPPG G PG G RGE G G GPPGP G +GP GP G PPGP Sbjct: 895 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954 Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854 G GL PG G++G KGD G G+ G+ G GL G PG G PG +G G G GP+G Sbjct: 955 GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012 Query: 2855 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 2907 PPGP GSP GS G GP G PG+PG G PGP+G K GEKG +G + V Sbjct: 1013 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072 Query: 2908 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 2954 A E G++ Q + + + GPPGPP G PG AG Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1126 Query: 2955 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004 GEPGP G+ G G PG GP G +GLPG GE+G G GP G PGPPG Sbjct: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186 Query: 3005 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 P+G + GPPGS GS G G G PG +G GPPG G Sbjct: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231 Score = 249 bits (635), Expect = 4e-65 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%) Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790 K P P Q VG PGP GPAG PG G +GE G G G G +G+ GPPGP G Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115 Query: 2791 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 2833 GP G G++ PG +G+QGM G G+ PG PG G GLPGPPG Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1175 Query: 2834 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891 PMGPPG G G G G GP GPPGS GS G G G+PG+ G+ G PG +G+ G Sbjct: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1235 Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951 KG+RG+ A +G + P PG PGPPG PG Sbjct: 1236 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285 Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 3009 AG G G G G PG PG GP GE G PG G+RG G++G G G G +GE+ Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1345 Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GPPG TG GP GP G+PG G+RG PGP G Sbjct: 1346 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1378 Score = 242 bits (618), Expect = 4e-63 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805 GPPGP G G PG G +GE G G +GPPGP G GP GP G GPQGP G + G Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1212 Query: 2806 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 2850 G +G G+AG PG PG G PG GPPG GPPGD G G G + Sbjct: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272 Query: 2851 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 2888 G G PGPPG PG PG GPSG+ G PG G+ GP G Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332 Query: 2889 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 2941 +GEKG +G+ ++ V Q +G+ + L IP + Q Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1389 Query: 2942 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 2997 GPPGP GPPG G +G+PG G G PG G+ GPPGE+G G++G GT G+ G Sbjct: 1390 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1449 Query: 2998 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G+PGP GP G GP G G++G GP G+ G+SG+ GPPG PG Sbjct: 1450 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Score = 239 bits (611), Expect = 2e-62 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%) Query: 2746 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 2798 +GP G PG AG G GPR G+ G++G GPPGP+G++GP G GPPG QG P Sbjct: 600 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 2858 +PG QG G G+ G G PG G PG GPP G PG G +G+ GA+GP GP GP Sbjct: 660 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 716 Query: 2859 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 2918 G PG GV G G G G G G G G KGD G + G Sbjct: 717 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 757 Query: 2919 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 2978 Q+ + + + + + GP G PGP G AG +G+ G PG PG PG QGP G Sbjct: 758 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 814 Query: 2979 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037 G PG G G G RG+ G PGP+G+ TGP GS G+RGP G PG G SG GP Sbjct: 815 STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872 Query: 3038 PGPPGYCDSSQCASIPYNGQGYPG 3061 PGPPG + P G+PG Sbjct: 873 PGPPG----ERGPQGPQGPVGFPG 892 Score = 239 bits (611), Expect = 2e-62 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P P + G PGP G +GG G GP GERG P GP+G +G PGP+GPPG Sbjct: 845 PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 898 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 P PG+ G G G GE G G+TG PG G GP GP G+ G G+ G GP Sbjct: 899 P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950 Query: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 2912 GPPG G PG+ G G G PG G G+ GP+GL+G G+RG +Q Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1001 Query: 2913 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 2972 + GP GPPGP GS G RG G G G PG PG Sbjct: 1002 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1039 Query: 2973 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 3025 QGPP GE+G PGEKG +G G GP GLPGP GP G G G G G PG Sbjct: 1040 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1097 Query: 3026 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G G+ G GPPGPPG I G G PG Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1132 Score = 239 bits (609), Expect = 4e-62 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%) Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 2796 GPPGP PGP GGPG+ G +GE SG GP GPRG GPPGP G PG +G Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546 Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856 G +PGE G +G +G G PGLPG G G GP GP GPPGD G G+DG +GPRG P Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 606 Query: 2857 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 GP G+PG+PG G +G G PG G GP G G G +G+ Q Sbjct: 607 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 661 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 2961 + G + P PG GPPG PG G GE PGP Sbjct: 662 --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 713 Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 3010 G G+PG G++G G RGL G KGE+G G G RG G GP+GE Sbjct: 714 QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 773 Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GP G G G PGP G+ G G G PG PGY P G+PG Sbjct: 774 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 820 Score = 227 bits (579), Expect = 1e-58 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 2777 ++GPPGP GP G PG +G +G G+ G +G G Sbjct: 707 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 766 Query: 2778 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 2822 PRG+ GP GP+G GP G G S +PG GRQG KG G PG PG Sbjct: 767 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826 Query: 2823 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 2869 G PG G GP GP G RG G G GP+ GPPGPPG G G G Sbjct: 827 EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 886 Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 2927 P G PG G G PG GL G G RG+ Q V Q +G+ + Sbjct: 887 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 944 Query: 2928 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 2981 R PGPPGPPG PG+A GA+G+PGP G G G G++G PGERG Sbjct: 945 ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 994 Query: 2982 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 3033 LPG +G G G GP+G PGP PG +G + T G PG G +GPPGP G G G Sbjct: 995 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054 Query: 3034 IRGPPGPPG 3042 +GP GP G Sbjct: 1055 EKGPQGPAG 1063 Score = 224 bits (571), Expect = 1e-57 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 2791 GPPGP G G G GP G++G G G PGP+G IGPPG PQG PP Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693 Query: 2792 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835 GP GP G + PG +G +G G G G G G G PG G M Sbjct: 694 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753 Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895 G GDRG G+ G G GP GP G G G GPSG+ G+ G G PG G G +G + Sbjct: 754 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813 Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 2949 G A + ++G+ Q P + +R G PGP GP Sbjct: 814 GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872 Query: 2950 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 3002 PG G RG GP G GFPG G GPPG+ GLPG G+RG TG GP G+ GP Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932 Query: 3003 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 3056 GP GE TGP G G GPPGPPG G G +G PGP G A + Sbjct: 933 QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 986 Query: 3057 QGYPG 3061 +G+PG Sbjct: 987 RGFPG 991 Score = 210 bits (534), Expect = 2e-53 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%) Query: 2747 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 2794 GPPGP GPAG PG +GP G G G GPPG G G G GPPG Sbjct: 403 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 2795 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844 G G +I + Q R ++G G GL GR G G PG G G GD G Sbjct: 463 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 522 Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 2901 G G GP GP G PG G PG G G PG+P GD G G GL G+KG RG+ Q Sbjct: 523 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 582 Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961 P R + G GP G PG AG RG GP Sbjct: 583 GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 617 Query: 2962 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 3007 G PG PG PGM GPPG +G G +GE G G+ GP+GLPGP GP G Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677 Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 + + G G G+ GPPG PG+ G SG +G GPPG P GYPG Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 721 Score = 201 bits (512), Expect = 7e-51 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GPPG PGPAG G G +GE G G GPPGP G+ GPPGP G GP G G G QG Sbjct: 1279 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1336 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 2863 +G KG+AG G PG+TG G GP G GP G RG G+ G G G GPPG G Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396 Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923 PG+ G G PG G+ G PG GL G G++G+ Sbjct: 1397 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1430 Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983 + R PG G PG G G G GP G PG PG PG QGP G +G Sbjct: 1431 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479 Query: 2984 GEKGERG-TGSSGPRGLPGPPG 3004 G G++G +G GP G PGPPG Sbjct: 1480 GPAGQKGDSGLPGPPGSPGPPG 1501 Score = 177 bits (449), Expect = 1e-43 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%) Query: 2748 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 2799 P PP GPG A+ E I+G A G G +G+ + PG +GPPGP GP G+ Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859 G PGL GP GP G PGDRG G+ G G G PGPP Sbjct: 414 M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 450 Query: 2860 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 2886 G+ GS G T GP G G+PG G PG S Sbjct: 451 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 510 Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946 G KGE GD G + + G + + R PG PG Sbjct: 511 GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 557 Query: 2947 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 2994 PG PG G RGE GP G PG PG GM+G GE RGLPGE G RG Sbjct: 558 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 615 Query: 2995 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 3042 GPRG PG PG G + GPPG G+ GP PGPPG+ GN G +G PGP G Sbjct: 616 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667 Score = 137 bits (346), Expect = 1e-31 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 2798 GP G PGP G G GP GE+G+ GA G PPGP G G PG +G PG +G G Sbjct: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1419 Query: 2799 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856 + PGEQG +G +G G G PG G G+PGP GP+GPPG G G G G +G Sbjct: 1420 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479 Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885 GP G G G+ GP G PG PG+ +P P Sbjct: 1480 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508 Score = 130 bits (327), Expect = 2e-29 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 + G GPPGP G PG G +G+ G G G PG G IGPPG QG G +G +PG Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1439 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 QG G KGD G PG G G PG PG PGP GP G++G TG G G G PGPPGSPG Sbjct: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1499 Query: 2865 PG 2866 PG Sbjct: 1500 PG 1501 Score = 90.5 bits (223), Expect = 2e-17 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 2778 +GPPG PG G PG+KG +G G+ G IGPPG P Sbjct: 1395 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1454 Query: 2779 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 2838 G +GPPGP G PGPQGP G G G G KGD+G P G PG PGPPG + P Sbjct: 1455 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1506 Score = 58.2 bits (139), Expect = 1e-07 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%) Query: 2933 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 2976 +Y+ ++P PP PG P GA GE G G P PGM +GP Sbjct: 346 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 404 Query: 2977 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 3036 PG +GP G+ GPPG QG TGPPG G R G PG G+ G Sbjct: 405 PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 442 Query: 3037 PPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG + Y G G G Sbjct: 443 ADGLPGPPGTMLMLPFRYGGDGSKG 467 Score = 47.0 bits (110), Expect = 3e-04 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%) Query: 2536 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 2588 S +G+S +G S S +AYR+ K A ++ PT L P G P +LF + P+ Sbjct: 50 SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108 Query: 2589 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 2648 F + I + Q+GV ++ F +D G+ + + G + Sbjct: 109 KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 2649 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 2706 H+V I V K+V + +DC + K D E + T+G + G + E IQ F Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223 Query: 2707 DIVCSP 2712 I P Sbjct: 224 LITGDP 229 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 254 bits (650), Expect = 7e-67 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 2794 GPPGPPG G PG G RGE G G GPPGP G +GP GP G PPGP Sbjct: 934 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993 Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854 G GL PG G++G KGD G G+ G+ G GL G PG G PG +G G G GP+G Sbjct: 994 GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051 Query: 2855 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 2907 PPGP GSP GS G GP G PG+PG G PGP+G K GEKG +G + V Sbjct: 1052 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111 Query: 2908 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 2954 A E G++ Q + + + GPPGPP G PG AG Sbjct: 1112 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1165 Query: 2955 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004 GEPGP G+ G G PG GP G +GLPG GE+G G GP G PGPPG Sbjct: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225 Query: 3005 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 P+G + GPPGS GS G G G PG +G GPPG G Sbjct: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270 Score = 249 bits (635), Expect = 4e-65 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%) Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790 K P P Q VG PGP GPAG PG G +GE G G G G +G+ GPPGP G Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154 Query: 2791 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 2833 GP G G++ PG +G+QGM G G+ PG PG G GLPGPPG Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1214 Query: 2834 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891 PMGPPG G G G G GP GPPGS GS G G G+PG+ G+ G PG +G+ G Sbjct: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1274 Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951 KG+RG+ A +G + P PG PGPPG PG Sbjct: 1275 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324 Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 3009 AG G G G G PG PG GP GE G PG G+RG G++G G G G +GE+ Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1384 Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GPPG TG GP GP G+PG G+RG PGP G Sbjct: 1385 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417 Score = 242 bits (618), Expect = 4e-63 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805 GPPGP G G PG G +GE G G +GPPGP G GP GP G GPQGP G + G Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1251 Query: 2806 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 2850 G +G G+AG PG PG G PG GPPG GPPGD G G G + Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311 Query: 2851 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 2888 G G PGPPG PG PG GPSG+ G PG G+ GP G Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371 Query: 2889 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 2941 +GEKG +G+ ++ V Q +G+ + L IP + Q Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1428 Query: 2942 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 2997 GPPGP GPPG G +G+PG G G PG G+ GPPGE+G G++G GT G+ G Sbjct: 1429 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1488 Query: 2998 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G+PGP GP G GP G G++G GP G+ G+SG+ GPPG PG Sbjct: 1489 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537 Score = 239 bits (611), Expect = 2e-62 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%) Query: 2746 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 2798 +GP G PG AG G GPR G+ G++G GPPGP+G++GP G GPPG QG P Sbjct: 639 IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 2858 +PG QG G G+ G G PG G PG GPP G PG G +G+ GA+GP GP GP Sbjct: 699 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 755 Query: 2859 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 2918 G PG GV G G G G G G G G KGD G + G Sbjct: 756 IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 796 Query: 2919 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 2978 Q+ + + + + + GP G PGP G AG +G+ G PG PG PG QGP G Sbjct: 797 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 853 Query: 2979 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037 G PG G G G RG+ G PGP+G+ TGP GS G+RGP G PG G SG GP Sbjct: 854 STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911 Query: 3038 PGPPGYCDSSQCASIPYNGQGYPG 3061 PGPPG + P G+PG Sbjct: 912 PGPPG----ERGPQGPQGPVGFPG 931 Score = 239 bits (611), Expect = 2e-62 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P P + G PGP G +GG G GP GERG P GP+G +G PGP+GPPG Sbjct: 884 PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 937 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 P PG+ G G G GE G G+TG PG G GP GP G+ G G+ G GP Sbjct: 938 P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989 Query: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 2912 GPPG G PG+ G G G PG G G+ GP+GL+G G+RG +Q Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1040 Query: 2913 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 2972 + GP GPPGP GS G RG G G G PG PG Sbjct: 1041 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1078 Query: 2973 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 3025 QGPP GE+G PGEKG +G G GP GLPGP GP G G G G G PG Sbjct: 1079 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1136 Query: 3026 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G G+ G GPPGPPG I G G PG Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1171 Score = 239 bits (609), Expect = 4e-62 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%) Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 2796 GPPGP PGP GGPG+ G +GE SG GP GPRG GPPGP G PG +G Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585 Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856 G +PGE G +G +G G PGLPG G G GP GP GPPGD G G+DG +GPRG P Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 645 Query: 2857 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 GP G+PG+PG G +G G PG G GP G G G +G+ Q Sbjct: 646 GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 700 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 2961 + G + P PG GPPG PG G GE PGP Sbjct: 701 --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 752 Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 3010 G G+PG G++G G RGL G KGE+G G G RG G GP+GE Sbjct: 753 QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 812 Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GP G G G PGP G+ G G G PG PGY P G+PG Sbjct: 813 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 859 Score = 227 bits (579), Expect = 1e-58 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 2777 ++GPPGP GP G PG +G +G G+ G +G G Sbjct: 746 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 805 Query: 2778 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 2822 PRG+ GP GP+G GP G G S +PG GRQG KG G PG PG Sbjct: 806 PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865 Query: 2823 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 2869 G PG G GP GP G RG G G GP+ GPPGPPG G G G Sbjct: 866 EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 925 Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 2927 P G PG G G PG GL G G RG+ Q V Q +G+ + Sbjct: 926 PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 983 Query: 2928 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 2981 R PGPPGPPG PG+A GA+G+PGP G G G G++G PGERG Sbjct: 984 ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 1033 Query: 2982 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 3033 LPG +G G G GP+G PGP PG +G + T G PG G +GPPGP G G G Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093 Query: 3034 IRGPPGPPG 3042 +GP GP G Sbjct: 1094 EKGPQGPAG 1102 Score = 224 bits (571), Expect = 1e-57 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 2791 GPPGP G G G GP G++G G G PGP+G IGPPG PQG PP Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732 Query: 2792 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835 GP GP G + PG +G +G G G G G G G PG G M Sbjct: 733 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 792 Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895 G GDRG G+ G G GP GP G G G GPSG+ G+ G G PG G G +G + Sbjct: 793 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852 Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 2949 G A + ++G+ Q P + +R G PGP GP Sbjct: 853 GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911 Query: 2950 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 3002 PG G RG GP G GFPG G GPPG+ GLPG G+RG TG GP G+ GP Sbjct: 912 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971 Query: 3003 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 3056 GP GE TGP G G GPPGPPG G G +G PGP G A + Sbjct: 972 QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 1025 Query: 3057 QGYPG 3061 +G+PG Sbjct: 1026 RGFPG 1030 Score = 210 bits (534), Expect = 2e-53 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%) Query: 2747 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 2794 GPPGP GPAG PG +GP G G G GPPG G G G GPPG Sbjct: 442 GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 501 Query: 2795 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844 G G +I + Q R ++G G GL GR G G PG G G GD G Sbjct: 502 DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 561 Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 2901 G G GP GP G PG G PG G G PG+P GD G G GL G+KG RG+ Q Sbjct: 562 GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 621 Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961 P R + G GP G PG AG RG GP Sbjct: 622 GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 656 Query: 2962 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 3007 G PG PG PGM GPPG +G G +GE G G+ GP+GLPGP GP G Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716 Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 + + G G G+ GPPG PG+ G SG +G GPPG P GYPG Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 760 Score = 201 bits (512), Expect = 7e-51 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GPPG PGPAG G G +GE G G GPPGP G+ GPPGP G GP G G G QG Sbjct: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1375 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 2863 +G KG+AG G PG+TG G GP G GP G RG G+ G G G GPPG G Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435 Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923 PG+ G G PG G+ G PG GL G G++G+ Sbjct: 1436 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1469 Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983 + R PG G PG G G G GP G PG PG PG QGP G +G Sbjct: 1470 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518 Query: 2984 GEKGERG-TGSSGPRGLPGPPG 3004 G G++G +G GP G PGPPG Sbjct: 1519 GPAGQKGDSGLPGPPGSPGPPG 1540 Score = 177 bits (449), Expect = 1e-43 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%) Query: 2748 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 2799 P PP GPG A+ E I+G A G G +G+ + PG +GPPGP GP G+ Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859 G PGL GP GP G PGDRG G+ G G G PGPP Sbjct: 453 M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 489 Query: 2860 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 2886 G+ GS G T GP G G+PG G PG S Sbjct: 490 GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 549 Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946 G KGE GD G + + G + + R PG PG Sbjct: 550 GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 596 Query: 2947 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 2994 PG PG G RGE GP G PG PG GM+G GE RGLPGE G RG Sbjct: 597 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 654 Query: 2995 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 3042 GPRG PG PG G + GPPG G+ GP PGPPG+ GN G +G PGP G Sbjct: 655 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706 Score = 137 bits (346), Expect = 1e-31 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 2798 GP G PGP G G GP GE+G+ GA G PPGP G G PG +G PG +G G Sbjct: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1458 Query: 2799 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856 + PGEQG +G +G G G PG G G+PGP GP+GPPG G G G G +G Sbjct: 1459 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518 Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885 GP G G G+ GP G PG PG+ +P P Sbjct: 1519 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547 Score = 130 bits (327), Expect = 2e-29 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 + G GPPGP G PG G +G+ G G G PG G IGPPG QG G +G +PG Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1478 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 QG G KGD G PG G G PG PG PGP GP G++G TG G G G PGPPGSPG Sbjct: 1479 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1538 Query: 2865 PG 2866 PG Sbjct: 1539 PG 1540 Score = 90.5 bits (223), Expect = 2e-17 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 2778 +GPPG PG G PG+KG +G G+ G IGPPG P Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1493 Query: 2779 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 2838 G +GPPGP G PGPQGP G G G G KGD+G P G PG PGPPG + P Sbjct: 1494 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1545 Score = 58.2 bits (139), Expect = 1e-07 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%) Query: 2933 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 2976 +Y+ ++P PP PG P GA GE G G P PGM +GP Sbjct: 385 EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 443 Query: 2977 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 3036 PG +GP G+ GPPG QG TGPPG G R G PG G+ G Sbjct: 444 PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 481 Query: 3037 PPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG + Y G G G Sbjct: 482 ADGLPGPPGTMLMLPFRYGGDGSKG 506 Score = 47.0 bits (110), Expect = 3e-04 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%) Query: 2536 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 2588 S +G+S +G S S +AYR+ K A ++ PT L P G P +LF + P+ Sbjct: 50 SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108 Query: 2589 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 2648 F + I + Q+GV ++ F +D G+ + + G + Sbjct: 109 KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 2649 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 2706 H+V I V K+V + +DC + K D E + T+G + G + E IQ F Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223 Query: 2707 DIVCSP 2712 I P Sbjct: 224 LITGDP 229 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 254 bits (649), Expect = 9e-67 Identities = 165/405 (40%), Positives = 185/405 (45%), Gaps = 88/405 (21%) Query: 2743 QDSVGPPGPPGPA-----GGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPN 2797 Q G PGPPGP+ G PG G GERG G G GP G GP GP GPPG GP Sbjct: 91 QGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPA 150 Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP--------------------------GP 2831 G+S+PG+ G+QG G G G PG G PG+P GP Sbjct: 151 GISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGP 210 Query: 2832 PGPMGPP-----------------GDRGFTGKDGAMGPRGPPGPP--------------G 2860 GP GPP GDRGF G+ G +GP GP GPP G Sbjct: 211 TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270 Query: 2861 SPGSPGVTGPSGKPGKPGDHGRPGP-----SGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915 +PG PG+ G G PG PG G PGP GL G KG+RG A Q L Sbjct: 271 APGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGL 330 Query: 2916 IS--GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP------PGSAGARGEPGPGGRPGF 2967 G M Q P S PGP G GP PG+ G RG PG G+PG+ Sbjct: 331 PGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGY 390 Query: 2968 PGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG-------ESRTGP---PGST 3017 PG PG+ GP G GLPG KG+ G G GP GLPGP GP G GP PG Sbjct: 391 PGKPGLDGPKGNPGLPGPKGDPGVG--GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIP 448 Query: 3018 GSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG-QGYPG 3061 G+RGP GPPG PG G +G PG PG + A+ NG G PG Sbjct: 449 GTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPG 493 Score = 244 bits (622), Expect = 1e-63 Identities = 144/328 (43%), Positives = 158/328 (48%), Gaps = 51/328 (15%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGP------PGPRGDIGPPGPQGPPGPQGPNGLS 2800 GP GP GP+G PG G RGE G+ G G PG G IGPPGPQGPPG +GP G+ Sbjct: 206 GPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIG 264 Query: 2801 IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPG-----------PMGPPGDRGFTGKDGA 2849 PG G G G G GLPG G G PGPPG GP G G G G Sbjct: 265 KPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGE 324 Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP---------SGLKGEKGDRGDIAS 2900 GP G PG PG G PG GP G G PG HG PGP +G G KG+RG S Sbjct: 325 QGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGS 384 Query: 2901 QNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG 2960 + G+ N + GPPG PGP G AGA+G PG Sbjct: 385 DG----------KPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPG 434 Query: 2961 ------PGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPP 3014 P G PG PGT G GPPG G PG KG+ G+ PGPPGP G + G Sbjct: 435 HNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS--------PGPPGPAGIATKGLN 486 Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G TG GPPGP G G G+ GPPGPPG Sbjct: 487 GPTGPPGPPGPRGHSGEPGLPGPPGPPG 514 Score = 235 bits (599), Expect = 6e-61 Identities = 153/358 (42%), Positives = 176/358 (49%), Gaps = 63/358 (17%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPP--GPQGPNGL- 2799 Q + GPPGP GP G PG GP G+ G G PG +G+ G PGP GP G G GL Sbjct: 59 QGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPSAVGKPGVPGLP 114 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--PPGDRGFTGKDGAMGPRGPPG 2857 PGE+G G KGD G GLPG G PG PG PGP G PG G G GA GPRG PG Sbjct: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174 Query: 2858 PPGSPGSPGVTGPSGK-----PGKPGDHGRPGPSGLKGEKGDRG-DIASQNMMRAVARQV 2911 G+PG PG+ G G+ PG+PG+ G PGP G G G G +N + Sbjct: 175 EKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIK 234 Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP--------GPPGSAGARGEPGPGG 2963 ++ G+M PGP GPP G PG+AGA G+PG G Sbjct: 235 GDRGFPGEMGPI---------------GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPG 279 Query: 2964 RPGFPGTPGMQGPP-----GERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE 3008 G PG PG+ GPP G+ GLPG KGERG G GP GLPG PG Sbjct: 280 TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG---- 335 Query: 3009 SRTGPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG--QGYPG 3061 TGPPG+ G +GP PG G PG G GP GP GY + P + GYPG Sbjct: 336 -LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392 Score = 223 bits (569), Expect = 2e-57 Identities = 130/286 (45%), Positives = 146/286 (51%), Gaps = 37/286 (12%) Query: 2767 RGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTP 2826 RG G GPPGP G G PGP GPPG G PG QG G+ G G P G+ G P Sbjct: 56 RGEQGTPGPPGPAGPRGHPGPSGPPGKP---GYGSPGLQGEPGLPGPPG-PSAVGKPGVP 111 Query: 2827 GLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS 2886 GLPG PG GP G +G G G GPRGPPGPPG PG G++ P GKPG+ G G PGP Sbjct: 112 GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGPR 170 Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946 G GEKG G + G + +M P R PGP GP Sbjct: 171 GFPGEKGAPG-------------------VPGMNGQKGEMGYGAPG-RPGERGLPGPQGP 210 Query: 2947 PGP--PGSAGARGEPGPGGRP------GFPGTPGMQGPPGERGLPGEKGERGTGSSGPRG 2998 GP P G RGE G G+P GFPG G GPPG +G PGE+G G G G G Sbjct: 211 TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270 Query: 2999 LPGPPGPQGESRTGPPGSTGSRGPPGPP--GRPGNSGIRGPPGPPG 3042 PG PG G G PG+ G GPPGPP G+PG G++G GP G Sbjct: 271 APGQPGIPGTK--GLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAG 314 Score = 186 bits (473), Expect = 2e-46 Identities = 123/318 (38%), Positives = 142/318 (44%), Gaps = 68/318 (21%) Query: 2742 TQDSVGPPGPPGPA-----GGPGAKGPRGERGISGAIGPPGPRGDIGP------PGPQGP 2790 T+ G PG GP G PG G +GERG +G G PG +G+ GP PG GP Sbjct: 280 TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGP 339 Query: 2791 P---GPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF 2843 P GPQGP G+ +PG +G G G AG PG G G+PG G PG G PG G Sbjct: 340 PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP 399 Query: 2844 TGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM 2903 G G GP+G PG G PG PG GP+G G PG +G GP G G G RG I Sbjct: 400 KGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI----- 454 Query: 2904 MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGG 2963 GPPG PG PGS G G PGP G Sbjct: 455 --------------------------------------GPPGIPGFPGSKGDPGSPGPPG 476 Query: 2964 RPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPP 3023 G T G+ GP G G PG +G +G G G PGPPGP G++ P G + P Sbjct: 477 PAGI-ATKGLNGPTGPPGPPGPRGH--SGEPGLPGPPGPPGPPGQA-VMPEGFIKAGQRP 532 Query: 3024 GPPGRP---GNSGIRGPP 3038 G P N G+ G P Sbjct: 533 SLSGTPLVSANQGVTGMP 550 Score = 136 bits (342), Expect = 4e-31 Identities = 90/258 (34%), Positives = 103/258 (39%), Gaps = 59/258 (22%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P P + GP G GPAG G G +GERG G+ G PG G G GP+G PG Sbjct: 345 PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG 404 Query: 2793 PQGPNG-------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 2845 GP G +PG G G KG G G G G PG+PG GP+GPPG GF G Sbjct: 405 LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG 464 Query: 2846 KDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905 G G GPPGP G + G+ GP+G PG PG G G GL G G Sbjct: 465 SKGDPGSPGPPGPAGI-ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPG------------ 511 Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 2965 PPGPPG + G G RP Sbjct: 512 -------------------------------------PPGPPGQ--AVMPEGFIKAGQRP 532 Query: 2966 GFPGTPGMQGPPGERGLP 2983 GTP + G G+P Sbjct: 533 SLSGTPLVSANQGVTGMP 550 Score = 133 bits (334), Expect = 3e-30 Identities = 92/216 (42%), Positives = 106/216 (49%), Gaps = 27/216 (12%) Query: 2843 FTGKDGAMGPRGPPGPPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIA 2899 +T K + RG G PG PG G GPSG PGKPG +G PG G G G G Sbjct: 46 YTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGP-- 102 Query: 2900 SQNMMRAVARQVCEQLIS--GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA--GA 2955 AV + L G+ + + P R PGPPG PGP G + G Sbjct: 103 -----SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGK 157 Query: 2956 RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGS---SGPRGLPGPPGPQGESRTG 3012 G+ GP G PG G PG +G PG G+ G+KGE G G+ G RGLPGP GP G S G Sbjct: 158 PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPS--G 215 Query: 3013 PPGSTGSRGPPGPPGRPGNSGIR------GPPGPPG 3042 PPG G RG G PG+PG G R GP GPPG Sbjct: 216 PPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250 Score = 42.0 bits (97), Expect = 0.009 Identities = 17/29 (58%), Positives = 19/29 (65%) Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043 G G+ GPPGP G G+ G GPPG PGY Sbjct: 57 GEQGTPGPPGPAGPRGHPGPSGPPGKPGY 85 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 253 bits (647), Expect = 2e-66 Identities = 148/337 (43%), Positives = 175/337 (51%), Gaps = 40/337 (11%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGER---GISGAIGPP------------- 2776 P P + VGPPGP G AG GA G RGE G +G GPP Sbjct: 793 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852 Query: 2777 --GPRGDIGPPGPQGP---PGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830 G +GD G PGPQGP PGPQGP G++ P G +G QG G G PG GR G PG G Sbjct: 853 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 912 Query: 2831 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890 PGP GPPG +GKDG G RG GPPG G PG+ GP+G PG+ G+ G GPSG +G Sbjct: 913 NPGPPGPPGP---SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969 Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950 G +G +A Q + + Q E+ G P+ + PG G GPP Sbjct: 970 PPGPQG-LAGQRGIVGLPGQRGERGFPGLPG---------PSGEPGKQGAPGASGDRGPP 1019 Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES 3009 G G G GP G PG G+PG GPPG G G KG+RG TG+ G G PGPPG G + Sbjct: 1020 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1079 Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 + G G G++GP GP G G GI+GP GP G Sbjct: 1080 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116 Score = 248 bits (634), Expect = 5e-65 Identities = 146/335 (43%), Positives = 166/335 (49%), Gaps = 60/335 (17%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GPPGPPGP+G G KG RG+ G G G PG +G GPPG +G PG GP+G G G Sbjct: 915 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE--GPPG 972 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866 QG+ G G GLPG+ G G PG PGP G PG +G GA G RGPPGP G PG G Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---APGASGDRGPPGPVGPPGLTG 1029 Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926 G G+ G PG G PG G G KGDRG+ + A Sbjct: 1030 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-------------------- 1069 Query: 2927 LNQIPNDYQSSRNQPGPPGPPGPPG---------SAGARGEPGPGGRPGFPGTPGMQGPP 2977 PGPPG PGP G AGA+G GP G G G G QGP Sbjct: 1070 --------------PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1115 Query: 2978 GERGLPGEKGERGT----GSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPGNS 3032 G++G GE GERG G +G +GLPGPPGP G+ +GP G +G RGPPGP G G Sbjct: 1116 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1175 Query: 3033 GIRG------PPGPPGYCDSSQCASIPYNGQGYPG 3061 G G PPGP G + A P N G PG Sbjct: 1176 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG 1209 Score = 248 bits (633), Expect = 7e-65 Identities = 150/360 (41%), Positives = 177/360 (49%), Gaps = 70/360 (19%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP----------------- 2785 Q VGP G PG G PG GP+G RG G +G PGP+G G P Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631 Query: 2786 -------GPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEP---------GLPGRTGT 2825 G GPPGP GP G PG G QG+ G G P G+PG G Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691 Query: 2826 PGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP---GKPGDHGR 2882 PGL GP G G PG+RG G G GPRG PG PG+ G G +GP+G P G PG G Sbjct: 692 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751 Query: 2883 P---GPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939 P G +G+ G KGDRGD+ + A + L +G + P + Sbjct: 752 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIG---------PPGPAGANG 801 Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TG 2992 + G GPPGP GSAGARG PG G G PG G GPPG G PG KGE+G G Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861 Query: 2993 SSGPRGLPGPPGPQGESR-TGPPGSTGSRGPPGPP---------GRPGNSGIRGPPGPPG 3042 + GP+G G PGPQG + TGP G+ G++GPPG G PG++G GPPGPPG Sbjct: 862 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921 Score = 243 bits (619), Expect = 3e-63 Identities = 172/477 (36%), Positives = 204/477 (42%), Gaps = 122/477 (25%) Query: 2672 KDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGK 2731 +D++EAG+ DG K + + ++C + + C P Sbjct: 26 QDVQEAGSCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGEC 85 Query: 2732 CPAFPNSCTCT----------------QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP 2775 CP P +D VGP GPPGP G G +GPRG+RG G G Sbjct: 86 CPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145 Query: 2776 PGPRG---------DIGPPGPQGPPGP---------------------------QGPNG- 2798 PGPRG + GPPGP GPPGP QGP G Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP 205 Query: 2799 ---------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA 2849 PG QG QG G+ GEPG+ G G G PGPPG PGD G GK G Sbjct: 206 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK---PGDDGEAGKPGK 262 Query: 2850 MGPRGPPGP------PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM 2903 G RGPPGP PG+PG PGV G G PG G G G G+KGE G G+ S Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322 Query: 2904 MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR---NQPGPPGPPGP---------PG 2951 M + + G+ R P +R QPGP GPPGP PG Sbjct: 323 MG-------PRGLPGERGRTG------PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 369 Query: 2952 SAGARGEPGPGGR---------PGFPGTPGMQGP------PGERGLPGEKGERGT-GSSG 2995 + GA+GE GP G G PGTPG GP PG G+PG KG G G +G Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 429 Query: 2996 PRGLP---GPPGPQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G P GPPGPQG + +TG PG G +G GP G PG +G +G PGP G Sbjct: 430 APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 486 Score = 242 bits (617), Expect = 5e-63 Identities = 146/338 (43%), Positives = 167/338 (49%), Gaps = 53/338 (15%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802 Q G PGP GP G G KG RG +G GA G PG G +GPPG G PGP GP P Sbjct: 866 QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-----P 920 Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------- 2855 G G+ G KG G+ G PGR G PGL GP GP G G+ G G GA GP GP Sbjct: 921 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 980 Query: 2856 -----PGPPGSPGSPGVTGPSGKPGK------PGDHGRPGPSGLKGEKGDRGDIASQNMM 2904 PG G G PG+ GPSG+PGK GD G PGP G G G G+ + Sbjct: 981 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 1040 Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP------------GS 2952 A G R + + PG PGPPG P G Sbjct: 1041 GA----------DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090 Query: 2953 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG- 3007 AGA+G GP G G G G QGP G++G GE GERG G +G +GLPGPPGP G Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1150 Query: 3008 ESRTGPPGSTGSRGPP---GPPGRPGNSGIRGPPGPPG 3042 + +GP G +G RGPP GP G+ G +GI GP GPPG Sbjct: 1151 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188 Score = 240 bits (612), Expect = 2e-62 Identities = 148/353 (41%), Positives = 172/353 (48%), Gaps = 39/353 (11%) Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 2799 GPPGP GPAGGPG A G +GE G +GA GP G +G G PG G PGP G +G Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGKDGAMGPR 2853 IPG +G G G AG PG PG G PG G GP+GP PG GF G+ G G Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473 Query: 2854 GPPGPPGSP------------GSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGD- 2897 GP GP G+P G PG GP G PG+ PG+ G PG GL G KG G+ Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 533 Query: 2898 ----IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA 2953 +A + E + G + + P PG G PGPPG Sbjct: 534 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593 Query: 2954 GARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE- 3008 GARG+PG G PG G G G GE+GLPG G RG G +G G PGP GP GE Sbjct: 594 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653 Query: 3009 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG +G +G PGPPG PG G G G PG + P +G+PG Sbjct: 654 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG-PRGERGFPG 705 Score = 240 bits (612), Expect = 2e-62 Identities = 153/397 (38%), Positives = 178/397 (44%), Gaps = 94/397 (23%) Query: 2747 GPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 G PG G G PGA G RG + G +GA GPPGP G G G QG PGP G GL PG Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--PG 669 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863 G G G G+ G+PG G PGL GP G G PG+RG G G GPRG PG PG+ G Sbjct: 670 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729 Query: 2864 SPGVTGPSGKPGK---PGDHGRPGP---SGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917 G +GP+G PG PG G PG +G+ G KGDRGD+ + A + L + Sbjct: 730 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-T 788 Query: 2918 GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP 2977 G + P + + G GPPGP GSAGARG PG G G PG G GPP Sbjct: 789 GPIG---------PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839 Query: 2978 GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES--------------------- 3009 G G PG KGE+G G+ GP+G G PGPQG + Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899 Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGN---------------------------------- 3031 R GPPGS G+ GPPGPPG G Sbjct: 900 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959 Query: 3032 -----SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061 SG GPPGP G +P +G+PG Sbjct: 960 GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996 Score = 240 bits (612), Expect = 2e-62 Identities = 135/301 (44%), Positives = 149/301 (49%), Gaps = 56/301 (18%) Query: 2747 GPPGPPGPAGGPGAKG---PRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 GP GPPGPAG G KG P G G +GA G PG RG+ GPPGP G GP PG Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------PG 840 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863 G+ G KG+ GE G G G PG GP G GP G G TG GA G +GPPG G PG Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900 Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923 + G GP G G PG G PGPSG G KG RGD Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-------------------------- 934 Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983 GPPG G PG G G PG G PG G G +GPPG +GL Sbjct: 935 -----------------SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 977 Query: 2984 GEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041 G++G G G G RG PG PGP GE + G PG++G RGPPGP G PG +G G PG Sbjct: 978 GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 1037 Query: 3042 G 3042 G Sbjct: 1038 G 1038 Score = 235 bits (599), Expect = 6e-61 Identities = 143/336 (42%), Positives = 167/336 (49%), Gaps = 35/336 (10%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGP---------RGDIG 2783 P P T G G PG AG G +GP+GE G +G G PGP RG+ G Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498 Query: 2784 PPGPQGPPGPQG-PNGLSIPGEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGPMGPPG 2839 GP GPPG +G P PG+ G G KG GE GL G G G PG PG G PG Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558 Query: 2840 DRGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 2896 RG TG+ G GP+G GP G+PG PG GP G G+PG G PGP G GE G G Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618 Query: 2897 D--IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PG 2948 + + +R + + E +G P R + G PGP PG Sbjct: 619 EKGLPGAPGLRGLPGKDGETGAAGPPG---------PAGPAGERGEQGAPGPSGFQGLPG 669 Query: 2949 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG 3007 PPG G G+PG G PG G PG+ GP GERG PGE+G G G GPRGLPG PG G Sbjct: 670 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729 Query: 3008 -ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 + +GP G G++GPPG G PG G G GP G Sbjct: 730 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765 Score = 159 bits (402), Expect = 4e-38 Identities = 97/238 (40%), Positives = 114/238 (47%), Gaps = 35/238 (14%) Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 G PG PGP+G PG A G G+RG G +GPPG G G PG +G PG GP PG Sbjct: 993 GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PG 1047 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863 G G+KGD GE G G G PG PG PGP GP G +G G+ GA GP GP GP G+ G Sbjct: 1048 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1107 Query: 2864 SPGVTGPSGKPGKPGDHGR------------------PGPSGLKGEKGDRGDIASQNMMR 2905 G GP G G+ G+ G PGPSG +G G G + Sbjct: 1108 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1167 Query: 2906 AVARQVCEQLISGQMNRFNQMLNQI-PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962 V SG+ + N + I P + + GP GPPG PG G G PGPG Sbjct: 1168 PVGP-------SGK-DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1217 Score = 112 bits (281), Expect = 4e-24 Identities = 59/134 (44%), Positives = 67/134 (50%), Gaps = 17/134 (12%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P+ P Q GP G G AG PG +G +G RG +G G PGP G G G GP G Sbjct: 1099 PSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG 1158 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 P GP G PG G +G G G PGP+GPPG RG +G+ G GP Sbjct: 1159 PSGPR-----------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201 Query: 2853 RGPPGPPGSPGSPG 2866 G PGPPG PG PG Sbjct: 1202 PGNPGPPGPPGPPG 1215 Score = 87.4 bits (215), Expect = 2e-16 Identities = 53/115 (46%), Positives = 56/115 (48%), Gaps = 22/115 (19%) Query: 2740 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799 T Q GPPGP G G G GP G RG G +GP G G G PGP GPPGP Sbjct: 1136 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP------ 1189 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPR 2853 +GR G G AG P G PG PGPPGP GP D F G +GPR Sbjct: 1190 -----RGRSGETGPAGPP------GNPGPPGPPGPPGPGIDMSAFAG----LGPR 1229 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 253 bits (647), Expect = 2e-66 Identities = 148/337 (43%), Positives = 175/337 (51%), Gaps = 40/337 (11%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGER---GISGAIGPP------------- 2776 P P + VGPPGP G AG GA G RGE G +G GPP Sbjct: 724 PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 783 Query: 2777 --GPRGDIGPPGPQGP---PGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830 G +GD G PGPQGP PGPQGP G++ P G +G QG G G PG GR G PG G Sbjct: 784 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 843 Query: 2831 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890 PGP GPPG +GKDG G RG GPPG G PG+ GP+G PG+ G+ G GPSG +G Sbjct: 844 NPGPPGPPGP---SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900 Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950 G +G +A Q + + Q E+ G P+ + PG G GPP Sbjct: 901 PPGPQG-LAGQRGIVGLPGQRGERGFPGLPG---------PSGEPGKQGAPGASGDRGPP 950 Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES 3009 G G G GP G PG G+PG GPPG G G KG+RG TG+ G G PGPPG G + Sbjct: 951 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1010 Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 + G G G++GP GP G G GI+GP GP G Sbjct: 1011 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047 Score = 248 bits (634), Expect = 5e-65 Identities = 146/335 (43%), Positives = 166/335 (49%), Gaps = 60/335 (17%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GPPGPPGP+G G KG RG+ G G G PG +G GPPG +G PG GP+G G G Sbjct: 846 GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE--GPPG 903 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866 QG+ G G GLPG+ G G PG PGP G PG +G GA G RGPPGP G PG G Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---APGASGDRGPPGPVGPPGLTG 960 Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926 G G+ G PG G PG G G KGDRG+ + A Sbjct: 961 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-------------------- 1000 Query: 2927 LNQIPNDYQSSRNQPGPPGPPGPPG---------SAGARGEPGPGGRPGFPGTPGMQGPP 2977 PGPPG PGP G AGA+G GP G G G G QGP Sbjct: 1001 --------------PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1046 Query: 2978 GERGLPGEKGERGT----GSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPGNS 3032 G++G GE GERG G +G +GLPGPPGP G+ +GP G +G RGPPGP G G Sbjct: 1047 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1106 Query: 3033 GIRG------PPGPPGYCDSSQCASIPYNGQGYPG 3061 G G PPGP G + A P N G PG Sbjct: 1107 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG 1140 Score = 248 bits (633), Expect = 7e-65 Identities = 150/360 (41%), Positives = 177/360 (49%), Gaps = 70/360 (19%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP----------------- 2785 Q VGP G PG G PG GP+G RG G +G PGP+G G P Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562 Query: 2786 -------GPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEP---------GLPGRTGT 2825 G GPPGP GP G PG G QG+ G G P G+PG G Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622 Query: 2826 PGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP---GKPGDHGR 2882 PGL GP G G PG+RG G G GPRG PG PG+ G G +GP+G P G PG G Sbjct: 623 PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682 Query: 2883 P---GPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939 P G +G+ G KGDRGD+ + A + L +G + P + Sbjct: 683 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIG---------PPGPAGANG 732 Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TG 2992 + G GPPGP GSAGARG PG G G PG G GPPG G PG KGE+G G Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792 Query: 2993 SSGPRGLPGPPGPQGESR-TGPPGSTGSRGPPGPP---------GRPGNSGIRGPPGPPG 3042 + GP+G G PGPQG + TGP G+ G++GPPG G PG++G GPPGPPG Sbjct: 793 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852 Score = 242 bits (617), Expect = 5e-63 Identities = 146/338 (43%), Positives = 167/338 (49%), Gaps = 53/338 (15%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802 Q G PGP GP G G KG RG +G GA G PG G +GPPG G PGP GP P Sbjct: 797 QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-----P 851 Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------- 2855 G G+ G KG G+ G PGR G PGL GP GP G G+ G G GA GP GP Sbjct: 852 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 911 Query: 2856 -----PGPPGSPGSPGVTGPSGKPGK------PGDHGRPGPSGLKGEKGDRGDIASQNMM 2904 PG G G PG+ GPSG+PGK GD G PGP G G G G+ + Sbjct: 912 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 971 Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP------------GS 2952 A G R + + PG PGPPG P G Sbjct: 972 GA----------DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021 Query: 2953 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG- 3007 AGA+G GP G G G G QGP G++G GE GERG G +G +GLPGPPGP G Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1081 Query: 3008 ESRTGPPGSTGSRGPP---GPPGRPGNSGIRGPPGPPG 3042 + +GP G +G RGPP GP G+ G +GI GP GPPG Sbjct: 1082 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119 Score = 240 bits (613), Expect = 1e-62 Identities = 158/387 (40%), Positives = 180/387 (46%), Gaps = 100/387 (25%) Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIG------------------PPGPRGDIGP 2784 +D VGP GPPGP G G +GPRG+RG G G PPGP G GP Sbjct: 44 KDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP 103 Query: 2785 PG------------------------PQGPPGPQGPNGLSIP-GEQGRQGMKGDAGEPGL 2819 PG QGP GP GP G P G G QG +G+ GEPG Sbjct: 104 PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGE 163 Query: 2820 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP------PGSPGSPGVTGPSGK 2873 PG +G G GPPGP G PGD G GK G G RGPPGP PG+PG PGV G G Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 223 Query: 2874 PGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPND 2933 PG G G G G+KGE G G+ S M + + G+ R P Sbjct: 224 PGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-------PRGLPGERGRTG------PAG 270 Query: 2934 YQSSR---NQPGPPGPPGP---------PGSAGARGEPGPGGR---------PGFPGTPG 2972 +R QPGP GPPGP PG+ GA+GE GP G G PGTPG Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330 Query: 2973 MQGP------PGERGLPGEKGERGT-GSSGPRGLP---GPPGPQG-------ESRTGPPG 3015 GP PG G+PG KG G G +G G P GPPGPQG + +TG PG Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390 Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G +G GP G PG +G +G PGP G Sbjct: 391 IAGFKGEQGPKGEPGPAGPQGAPGPAG 417 Score = 240 bits (612), Expect = 2e-62 Identities = 148/353 (41%), Positives = 172/353 (48%), Gaps = 39/353 (11%) Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 2799 GPPGP GPAGGPG A G +GE G +GA GP G +G G PG G PGP G +G Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGKDGAMGPR 2853 IPG +G G G AG PG PG G PG G GP+GP PG GF G+ G G Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404 Query: 2854 GPPGPPGSP------------GSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGD- 2897 GP GP G+P G PG GP G PG+ PG+ G PG GL G KG G+ Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 464 Query: 2898 ----IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA 2953 +A + E + G + + P PG G PGPPG Sbjct: 465 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 524 Query: 2954 GARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE- 3008 GARG+PG G PG G G G GE+GLPG G RG G +G G PGP GP GE Sbjct: 525 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584 Query: 3009 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 G PG +G +G PGPPG PG G G G PG + P +G+PG Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG-PRGERGFPG 636 Score = 240 bits (612), Expect = 2e-62 Identities = 153/397 (38%), Positives = 178/397 (44%), Gaps = 94/397 (23%) Query: 2747 GPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 G PG G G PGA G RG + G +GA GPPGP G G G QG PGP G GL PG Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--PG 600 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863 G G G G+ G+PG G PGL GP G G PG+RG G G GPRG PG PG+ G Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660 Query: 2864 SPGVTGPSGKPGK---PGDHGRPGP---SGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917 G +GP+G PG PG G PG +G+ G KGDRGD+ + A + L + Sbjct: 661 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-T 719 Query: 2918 GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP 2977 G + P + + G GPPGP GSAGARG PG G G PG G GPP Sbjct: 720 GPIG---------PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770 Query: 2978 GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES--------------------- 3009 G G PG KGE+G G+ GP+G G PGPQG + Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830 Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGN---------------------------------- 3031 R GPPGS G+ GPPGPPG G Sbjct: 831 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890 Query: 3032 -----SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061 SG GPPGP G +P +G+PG Sbjct: 891 GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927 Score = 240 bits (612), Expect = 2e-62 Identities = 135/301 (44%), Positives = 149/301 (49%), Gaps = 56/301 (18%) Query: 2747 GPPGPPGPAGGPGAKG---PRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 GP GPPGPAG G KG P G G +GA G PG RG+ GPPGP G GP PG Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------PG 771 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863 G+ G KG+ GE G G G PG GP G GP G G TG GA G +GPPG G PG Sbjct: 772 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831 Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923 + G GP G G PG G PGPSG G KG RGD Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-------------------------- 865 Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983 GPPG G PG G G PG G PG G G +GPPG +GL Sbjct: 866 -----------------SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 908 Query: 2984 GEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041 G++G G G G RG PG PGP GE + G PG++G RGPPGP G PG +G G PG Sbjct: 909 GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 968 Query: 3042 G 3042 G Sbjct: 969 G 969 Score = 235 bits (599), Expect = 6e-61 Identities = 143/336 (42%), Positives = 167/336 (49%), Gaps = 35/336 (10%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGP---------RGDIG 2783 P P T G G PG AG G +GP+GE G +G G PGP RG+ G Sbjct: 370 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 429 Query: 2784 PPGPQGPPGPQG-PNGLSIPGEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGPMGPPG 2839 GP GPPG +G P PG+ G G KG GE GL G G G PG PG G PG Sbjct: 430 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489 Query: 2840 DRGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 2896 RG TG+ G GP+G GP G+PG PG GP G G+PG G PGP G GE G G Sbjct: 490 ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549 Query: 2897 D--IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PG 2948 + + +R + + E +G P R + G PGP PG Sbjct: 550 EKGLPGAPGLRGLPGKDGETGAAGPPG---------PAGPAGERGEQGAPGPSGFQGLPG 600 Query: 2949 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG 3007 PPG G G+PG G PG G PG+ GP GERG PGE+G G G GPRGLPG PG G Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660 Query: 3008 -ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 + +GP G G++GPPG G PG G G GP G Sbjct: 661 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696 Score = 234 bits (597), Expect = 1e-60 Identities = 150/382 (39%), Positives = 172/382 (45%), Gaps = 104/382 (27%) Query: 2746 VGPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGP--------------- 2787 +GP GPPGPAG PG +G +G E G G GP GPRG GPPG Sbjct: 137 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196 Query: 2788 QGPPGPQGPNGL----SIPGEQGRQ------GMKGDAGEPGLPGRTGTPGLPGPPGPMGP 2837 +GPPGPQG G +PG +G + G KG+AG PG+ G +G+PG G PGPMGP Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256 Query: 2838 ---PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGD 2894 PG+RG TG GA G RG G PG G PG GP+G PG PG G G +G G +G Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG- 315 Query: 2895 RGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP----- 2949 P Q R +PG PG PGP Sbjct: 316 ------------------------------------PEGAQGPRGEPGTPGSPGPAGASG 339 Query: 2950 -------PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSG 2995 PG+ G+ G PG G PGFPG G GP G G G KG+ G G G Sbjct: 340 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG 399 Query: 2996 PRGLPGPPGPQG-------ESRTGPPGSTGSRGPPGPPGR---------PGNSGIRGPPG 3039 P+G PGP GPQG E + G G G GP GPPG PG G+ GP G Sbjct: 400 PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG 459 Query: 3040 PPGYCDSSQCASIPYNGQGYPG 3061 PG S A P G PG Sbjct: 460 APGERGPSGLAG-PKGANGDPG 480 Score = 220 bits (560), Expect = 2e-56 Identities = 145/340 (42%), Positives = 163/340 (47%), Gaps = 56/340 (16%) Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGA---IGPPGPRGDIGPP------GPQGPP 2791 GPPGP PG G PG KG RG G+ GA G PG +G+ G P GP GP Sbjct: 198 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 257 Query: 2792 GPQGPNGLSIP----GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 2847 G G G + P G +G G G AG PG G G PG PG PG G G G G + Sbjct: 258 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317 Query: 2848 GAMGPRGPPGPPGSPGSPGVT---GPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 2904 GA GPRG PG PGSPG G + G G PG G G PG +G G G RG Q Sbjct: 318 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377 Query: 2905 RAVA--RQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA------GAR 2956 + Q E I+G Q + +PGP GP G PG A GAR Sbjct: 378 GPLGPKGQTGEPGIAGFKGE------------QGPKGEPGPAGPQGAPGPAGEEGKRGAR 425 Query: 2957 GEP---GPGGRPGFPGTPGMQGPPGERGLPGEK---GERG-TGSSGPRGLPGPPGPQGE- 3008 GEP GP G PG G PG +G PG+ GL G K GERG +G +GP+G G PG GE Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485 Query: 3009 ------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 TG PG G +G GP G PG G GPPGP G Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 525 Score = 173 bits (438), Expect = 3e-42 Identities = 118/309 (38%), Positives = 131/309 (42%), Gaps = 95/309 (30%) Query: 2799 LSIPGEQGRQ-GMKGDAGEPG----LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853 L G+ RQ G KG GEPG + G G PG GP G GP GDRG G+ GA GPR Sbjct: 21 LRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 80 Query: 2854 G------PPGPPGSPGSP---------------------------------GVTGPSGKP 2874 G PG PG PG P G GP G Sbjct: 81 GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140 Query: 2875 GKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY 2934 G PG G PGP G +G G+ G E +SG M Sbjct: 141 GPPGPAGAPGPQGFQGNPGEPG----------------EPGVSGPM-------------- 170 Query: 2935 QSSRNQPGPPGPP------GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGE 2988 R PGPPG P G PG AG RG PGP G GFPGTPG+ G G RG PG G Sbjct: 171 -GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA 229 Query: 2989 RG----------TGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGPPGPPGRPGNSGI 3034 +G +GS G G PGP GP+G RTGP G+ G+RG G PG G G Sbjct: 230 KGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP 289 Query: 3035 RGPPGPPGY 3043 GP G PG+ Sbjct: 290 VGPAGGPGF 298 Score = 159 bits (402), Expect = 4e-38 Identities = 97/238 (40%), Positives = 114/238 (47%), Gaps = 35/238 (14%) Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803 G PG PGP+G PG A G G+RG G +GPPG G G PG +G PG GP PG Sbjct: 924 GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PG 978 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863 G G+KGD GE G G G PG PG PGP GP G +G G+ GA GP GP GP G+ G Sbjct: 979 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1038 Query: 2864 SPGVTGPSGKPGKPGDHGR------------------PGPSGLKGEKGDRGDIASQNMMR 2905 G GP G G+ G+ G PGPSG +G G G + Sbjct: 1039 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1098 Query: 2906 AVARQVCEQLISGQMNRFNQMLNQI-PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962 V SG+ + N + I P + + GP GPPG PG G G PGPG Sbjct: 1099 PVGP-------SGK-DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1148 Score = 112 bits (281), Expect = 4e-24 Identities = 59/134 (44%), Positives = 67/134 (50%), Gaps = 17/134 (12%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P+ P Q GP G G AG PG +G +G RG +G G PGP G G G GP G Sbjct: 1030 PSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG 1089 Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852 P GP G PG G +G G G PGP+GPPG RG +G+ G GP Sbjct: 1090 PSGPR-----------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132 Query: 2853 RGPPGPPGSPGSPG 2866 G PGPPG PG PG Sbjct: 1133 PGNPGPPGPPGPPG 1146 Score = 111 bits (277), Expect = 1e-23 Identities = 83/238 (34%), Positives = 91/238 (38%), Gaps = 94/238 (39%) Query: 2879 DHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938 D +PGP G KGE GD DI Sbjct: 27 DVRQPGPKGQKGEPGDIKDIVGPK------------------------------------ 50 Query: 2939 NQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989 GPPGP GP G G RG+ PGP GR G PGTPG GPPG G PG G Sbjct: 51 ---GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107 Query: 2990 GT-------------------------GSSGPRGLPGP---PGPQG-ESRTGPPGS---- 3016 G G GPRG PGP PGPQG + G PG Sbjct: 108 GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167 Query: 3017 --TGSRGPPGPPGRPGN---------SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061 G RGPPGPPG+PG+ +G RGPPGP G +P +GYPG Sbjct: 168 GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPG 225 Score = 87.4 bits (215), Expect = 2e-16 Identities = 53/115 (46%), Positives = 56/115 (48%), Gaps = 22/115 (19%) Query: 2740 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799 T Q GPPGP G G G GP G RG G +GP G G G PGP GPPGP Sbjct: 1067 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP------ 1120 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPR 2853 +GR G G AG P G PG PGPPGP GP D F G +GPR Sbjct: 1121 -----RGRSGETGPAGPP------GNPGPPGPPGPPGPGIDMSAFAG----LGPR 1160 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 253 bits (647), Expect = 2e-66 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 2792 GPPGPPG G GA GP+G+RG G GPPG P+GD+GP PGP GPPG Sbjct: 757 GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Query: 2793 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 2837 P GP G+ PG G G KGD G PGL PG G+PG+PG PGP+GP Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 2838 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885 PG G GK GA MGP GPPGP G PG GV G G G G G PGP Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 2935 +G KG KG+ G + + L+ + + L I P YQ Sbjct: 937 TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 2936 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 2976 QPG PGPPGP G+ G G+PG PG G GFPG G++GP Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 2977 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 3029 PG GLPG+KG++G GLPG PGP+GE G PG GS G PG PG P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 3030 GNSGIRGPPGPPGY 3043 G G +G PG PG+ Sbjct: 1110 GTPGAKGQPGLPGF 1123 Score = 246 bits (629), Expect = 2e-64 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%) Query: 2746 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799 +GPPGPPGP +G PG KG G +G G GP G +G G PG GPPGP PN L Sbjct: 901 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Query: 2800 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 2838 IPG G +G +G G+PG PG +G PGLPGPPGP G P Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 2839 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 2887 GD GF G G GP GP G PG PGSPG+ G G G PG G PG G Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080 Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 2946 KGE G G + + +V L + L P PGPPGP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133 Query: 2947 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 2995 GPPG+ G GEPGP GG PG PG PG +G PG+ G+P GE G+ G G+ G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 2996 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 P GLPG G +G+ G PG+ G GP G PG G G++GPPGPPG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Score = 238 bits (608), Expect = 5e-62 Identities = 148/329 (44%), Positives = 170/329 (51%), Gaps = 25/329 (7%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQG 2789 P P + + G PG PGP GG PG GP GE+G G G PGP G G PG G Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188 Query: 2790 --PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 2847 PGP G GLS G++G G+ G G PGLPG G PG G PG GPPG G G Sbjct: 1189 FGNPGPPGLPGLS--GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP- 1245 Query: 2848 GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 GP+G PGP G PG PG TG G PG G G PG G+KGEKG+ G + Sbjct: 1246 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1305 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 2965 Q L Q N LN + D PG GP G PGSAG GEPG G P Sbjct: 1306 GDQGPPGL---QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1362 Query: 2966 GFPGTPG-------MQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGE-SRTGPPGS 3016 G PG PG ++G G G+PG+ G +G G GP+GLPGP GP G+ R G PG Sbjct: 1363 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF 1422 Query: 3017 TGS---RGPPGPPGRPGNSGIRGPPGPPG 3042 G+ +G PG PG+PG G+ GPPGP G Sbjct: 1423 DGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1451 Score = 237 bits (604), Expect = 2e-61 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 2800 +G PGPPGP G PG GP G G G IG GP G G PGP+G PGP GP GL Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764 Query: 2801 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 2843 PG +G G KGD G PG PGRTG GLPGP PGPMGPPG G Sbjct: 765 -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 2844 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 2880 G G G +G PGPP GSPG PG GP G PG PG Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883 Query: 2881 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938 G+ G SG G KG+ G + + + + G Q P + S+ Sbjct: 884 GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 2939 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 2996 +PG PGPPGP P G++GE G PG PG PG+ GP G +GLPG+ G+ G SG Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998 Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 3042 GLPGPPGP+G G PG G GPPG G PG G+ GPPGP G Sbjct: 999 PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048 Score = 236 bits (601), Expect = 3e-61 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%) Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 2798 D + PGPPGP G PG KG +GE+G+ G G G GPPG G PG GP G Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 2857 L PG++G +G G G GLPG G PG PG PG G PGD F G G G G PG Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 2858 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917 PG PG PG G G PG PG G PG KGE+G G+ + + Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617 Query: 2918 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 2965 G M F Q PG PG PGP PG G G PG G Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019 G PG PG+ G PG G+PG KGE G G GP+G PG PGP G G PG G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735 Query: 3020 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GPPGPPG PG G + GPPGPPG + A P +G+PG Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781 Score = 234 bits (596), Expect = 1e-60 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%) Query: 2710 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 2769 CSP S+ C I + E P + G PG PGP G PG PRG++G Sbjct: 32 CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79 Query: 2770 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 2825 G GPPGP+G GPPG G PG G G+ PG QG G G GE G PG G Sbjct: 80 DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Query: 2826 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 2876 PGL GPPGP G PG +G G G G GPPG G PG G+ GP G PG Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 2877 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 2935 PG G PGP GL G KG+ G + Q Q Q G + ++ I ++Q Sbjct: 200 PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257 Query: 2936 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 2973 R PGPP GPPGPP G G +GEPG PG G+PG PG PG Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317 Query: 2974 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 3009 G PGE G GEKG++G TG GP GLPG PG +GE Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377 Query: 3010 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 3042 GPPG G GPPGPPG PG G +G GPPG Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415 Score = 231 bits (588), Expect = 1e-59 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GP G PG G PG +G G GI G IGPPGP G +GPPGP G PGP+G GL+ G +G Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227 Query: 2807 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 2849 +G +G G PG PG+ G GLPG GP GPPG RG G + G Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 2909 G +G PG G PG G G G PG PGD G PG G GEKG +GD V Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 2910 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 2956 + + G+ L +P + Q PGPPG PPGPPG G R Sbjct: 348 RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 2957 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 3003 G+ G G PG PG PG+ G PG GLPG G G G GP G PG Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 3004 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 3046 G QGE +GPPG G G PGPPG G G +G G G Sbjct: 466 GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525 Query: 3047 SQCASIP--YNGQGYPGS 3062 IP G+PGS Sbjct: 526 KGLPGIPGAPGAPGFPGS 543 Score = 228 bits (582), Expect = 5e-59 Identities = 144/342 (42%), Positives = 167/342 (48%), Gaps = 32/342 (9%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 S+G PG PGP G PG G G GI G++G PG G G PG +G PG G G PG Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 2855 G +G+ G G PGLPG G G G PG GPPG++G G+DG GP G Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 2856 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913 PGPPG PG G G G PG PG+ G PGP G G G G + + Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL-- 1247 Query: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 2973 + G P +Q PGP GPPG PG+ G +GE G G+PG PG PG+ Sbjct: 1248 EGPKGNPGPQGPPGRPGPTGFQ---GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1304 Query: 2974 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 3025 QGPPG +G PG G G G G G+PG PG +G S GP G G GPPGP Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364 Query: 3026 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 3061 PG PG SG I+G GPPG + P QG PG Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406 Score = 223 bits (568), Expect = 2e-57 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 2804 G PG PGP G G G +GE+G +GA GP G G G PG G PG +G G L+ PG Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 MKGD GE G PG G PGLPG PG G PG G G+ G + +G GPPG+PG Sbjct: 556 -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610 Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 2918 PG+ G G G PG G PGP G KG +G G+ + Q + + G Sbjct: 611 PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669 Query: 2919 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 2965 R + +P D S+ +PG P G PGPPG G G PGP G P Sbjct: 670 NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727 Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 3007 G PG G++GPPG G PG KGE G G G RG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787 Query: 3008 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 3042 + GP G G G PGP G PG G++GPPGPPG Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828 Score = 219 bits (557), Expect = 4e-56 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 2800 G PG PGP G PG +GERG G G PG G+IGP GP G PPGP G G+ Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 2801 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 2848 PG+ G G KGD G+ PG PGR G GLPG PG G PG G G G Sbjct: 642 NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701 Query: 2849 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905 +G GPPGP G PG PG G G PG+ G G PGP G G KG+ G Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753 Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 2956 A+ + G F L + R PGPPGPPG P G G Sbjct: 754 ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 2957 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 3015 G+PGP G PG PG G+QGPPG G+PG G+ G G G +G PGPPG PG Sbjct: 805 GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857 Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 G RG PG PG PG G G PG PG +S G+PG+ Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894 Score = 218 bits (555), Expect = 7e-56 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%) Query: 2747 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 2792 GPPGPPG G PG KG +GE+G G G PG G+ G PG G PG Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 2793 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830 P GP GL IP G G G+ G+ GE G PG G PGLPG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386 Query: 2831 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 2872 PPG MGPPG GF G+ G G GPPG PG+PG PG GP+G Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446 Query: 2873 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 2927 +PG PG G PG GL+GE+G +GD C I ++ Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490 Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 2975 PG PG PG PG G+ G P GP G PG PG PG G Sbjct: 491 -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539 Query: 2976 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 3015 PG +G P G+KGE G+ G+ G GLPG PGP+GE P G Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595 Query: 3016 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 3043 T G RGPPG PG PG G GP GPPG+ Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625 Score = 209 bits (532), Expect = 3e-53 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 2763 P FP S D + PG G G PG GP Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597 Query: 2764 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 2816 +GERG G G PG G+IGP GP GPPGP G G+ PG+ G G KGD G+ Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 2817 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 2861 PG PGR G GLPG PG G PG G G G +G GPPGP G Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717 Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921 PG PG G G PG+ G G PGP G G KG+ G A+ + G Sbjct: 718 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766 Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 2972 F L + R PGPPGP PGP G G G+PGP G PG PG G Sbjct: 767 -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819 Query: 2973 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 3025 +QGPPG G+PG G+ G G G +G PGP PGP GE G PG+ G GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 3026 PGRPGNS------------GIRGPPGPPG 3042 PG PG + G+ GPPGPPG Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 208 bits (530), Expect = 6e-53 Identities = 125/300 (41%), Positives = 140/300 (46%), Gaps = 66/300 (22%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP--------PGPQGPPGPQGPNG 2798 G PG PG G PG KG G G G GPPGP G GP PGPQGPPG GP G Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTG 1267 Query: 2799 LS-IPGEQGRQGMKGDAG---EPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854 +PG +G G+ G+ G E G PG+ G PGLPG G GPPG +G G+ G G +G Sbjct: 1268 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1327 Query: 2855 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914 PG PG PG PG+ GPSG PG G G PG G G G G +++ Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK--------- 1378 Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 2974 G GPPG PG G +G PGP G G PG G Sbjct: 1379 ---------------------------GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPP 1411 Query: 2975 GPPGERGLPG------EKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPG 3027 G PG GLPG KG+ G G G RGL GPPGP G +GPPGPPG Sbjct: 1412 GDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD-----------GLQGPPGPPG 1460 Score = 204 bits (520), Expect = 8e-52 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%) Query: 2745 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 2795 ++GP GPPG P G G KG +G G G G PGP+GD G PG G PG G Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 2796 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 2833 GL +PG+ G G+ G GEPG+PG G PG+PGPPG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 2834 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 2874 P GPPG G G GA+GP+G G PG PG PG TG G P Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 2875 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931 G GD +G+PGP G G G I Q I G + + L+ IP Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842 Query: 2932 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989 + + PGPPG PGPPG G+ G PG G G PG+PG+ G G G PG KGE Sbjct: 843 GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898 Query: 2990 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 3042 G G PGPPGP G R+G PG G G G PG PG +G +G PGPPG Sbjct: 899 GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 3043 YCDSSQCASIPYNGQ-GYPG 3061 D + S G+ G PG Sbjct: 954 PMDPNLLGSKGEKGEPGLPG 973 Score = 139 bits (349), Expect = 6e-32 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G PG PG G PG KGP G + G+ GP G G IGPPGP G PGP G + + I G+ G Sbjct: 1327 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1382 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866 G+ G G GLPG G GLPGP GP G PG G G DGA G +G PG PG PG+ G Sbjct: 1383 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1442 Query: 2867 VTGPSGKPGKPGDHGRPGPSGL 2888 + GP G G G G PG S + Sbjct: 1443 LDGPPGPDGLQGPPGPPGTSSV 1464 Score = 105 bits (263), Expect = 5e-22 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000 PGP GPPGP G G G PGP G G G PG+ G PG GLPG G G+ GP+G+P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122 Query: 3001 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 3050 G G +GE G PG G +GPPGPPG PG G + GP G PGY Sbjct: 123 GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182 Query: 3051 SIPYNGQGYPG 3061 +P G PG Sbjct: 183 GLP-GPTGIPG 192 Score = 90.9 bits (224), Expect = 2e-17 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007 G G G RG PG G PG PG PG +GPPG RG G+ G G GP+G+ GPPG G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99 Query: 3008 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043 T G PG G+ GP G PG G G RG PG PG+ Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Score = 75.1 bits (183), Expect = 1e-12 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%) Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 2997 G P A A PG + G G +G G GL G G G G GPR Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 2998 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 3057 G+PGPPGP+G GPPG G G PG PG PG+ G GP G PG C+ ++ + Sbjct: 81 GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131 Query: 3058 GYPGS 3062 G+PGS Sbjct: 132 GFPGS 136 Score = 60.8 bits (146), Expect = 2e-08 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800 GPPG PG G PG G G +G G G PG RG GPPGP QGPPGP G + ++ Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 253 bits (647), Expect = 2e-66 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 2792 GPPGPPG G GA GP+G+RG G GPPG P+GD+GP PGP GPPG Sbjct: 757 GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Query: 2793 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 2837 P GP G+ PG G G KGD G PGL PG G+PG+PG PGP+GP Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 2838 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885 PG G GK GA MGP GPPGP G PG GV G G G G G PGP Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 2935 +G KG KG+ G + + L+ + + L I P YQ Sbjct: 937 TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 2936 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 2976 QPG PGPPGP G+ G G+PG PG G GFPG G++GP Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 2977 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 3029 PG GLPG+KG++G GLPG PGP+GE G PG GS G PG PG P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 3030 GNSGIRGPPGPPGY 3043 G G +G PG PG+ Sbjct: 1110 GTPGAKGQPGLPGF 1123 Score = 246 bits (629), Expect = 2e-64 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%) Query: 2746 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799 +GPPGPPGP +G PG KG G +G G GP G +G G PG GPPGP PN L Sbjct: 901 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Query: 2800 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 2838 IPG G +G +G G+PG PG +G PGLPGPPGP G P Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 2839 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 2887 GD GF G G GP GP G PG PGSPG+ G G G PG G PG G Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080 Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 2946 KGE G G + + +V L + L P PGPPGP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133 Query: 2947 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 2995 GPPG+ G GEPGP GG PG PG PG +G PG+ G+P GE G+ G G+ G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 2996 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 P GLPG G +G+ G PG+ G GP G PG G G++GPPGPPG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Score = 239 bits (611), Expect = 2e-62 Identities = 156/372 (41%), Positives = 186/372 (50%), Gaps = 56/372 (15%) Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 2782 +P + E P +P + + SVG PG PG G PGAKG G G G GPPGP+G Sbjct: 1078 LPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136 Query: 2783 GPPGPQGPPGPQGPNG-------LSIPGEQGRQGM---------KGDAGEPG-------- 2818 GPPG G PG GP G PGE+G+ G KG+ G+PG Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 2819 ---LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP--------GSPGV 2867 L G+ G GLPG PG G PG +G G G G +GPPGPPGSP G+PG Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256 Query: 2868 TGPSGKPGKPGDH---GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924 GP G+PG PG G PG G+KGEKG+ G + Q L Q N Sbjct: 1257 QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL---QGNPGR 1313 Query: 2925 QMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG-------MQG 2975 LN + D PG GP G PGSAG GEPG G PG PG PG ++G Sbjct: 1314 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1373 Query: 2976 PPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPP---GSTGSRGPPGPPGRPG 3030 G G+PG+ G +G G GP+GLPGP GP G+ R G P G+ G +G PG PG+PG Sbjct: 1374 DAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG 1433 Query: 3031 NSGIRGPPGPPG 3042 G+ GPPGP G Sbjct: 1434 TRGLDGPPGPDG 1445 Score = 237 bits (604), Expect = 2e-61 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 2800 +G PGPPGP G PG GP G G G IG GP G G PGP+G PGP GP GL Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764 Query: 2801 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 2843 PG +G G KGD G PG PGRTG GLPGP PGPMGPPG G Sbjct: 765 -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 2844 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 2880 G G G +G PGPP GSPG PG GP G PG PG Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883 Query: 2881 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938 G+ G SG G KG+ G + + + + G Q P + S+ Sbjct: 884 GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 2939 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 2996 +PG PGPPGP P G++GE G PG PG PG+ GP G +GLPG+ G+ G SG Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998 Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 3042 GLPGPPGP+G G PG G GPPG G PG G+ GPPGP G Sbjct: 999 PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048 Score = 236 bits (601), Expect = 3e-61 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%) Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 2798 D + PGPPGP G PG KG +GE+G+ G G G GPPG G PG GP G Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 2857 L PG++G +G G G GLPG G PG PG PG G PGD F G G G G PG Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 2858 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917 PG PG PG G G PG PG G PG KGE+G G+ + + Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617 Query: 2918 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 2965 G M F Q PG PG PGP PG G G PG G Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019 G PG PG+ G PG G+PG KGE G G GP+G PG PGP G G PG G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735 Query: 3020 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GPPGPPG PG G + GPPGPPG + A P +G+PG Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781 Score = 234 bits (596), Expect = 1e-60 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%) Query: 2710 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 2769 CSP S+ C I + E P + G PG PGP G PG PRG++G Sbjct: 32 CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79 Query: 2770 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 2825 G GPPGP+G GPPG G PG G G+ PG QG G G GE G PG G Sbjct: 80 DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Query: 2826 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 2876 PGL GPPGP G PG +G G G G GPPG G PG G+ GP G PG Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 2877 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 2935 PG G PGP GL G KG+ G + Q Q Q G + ++ I ++Q Sbjct: 200 PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257 Query: 2936 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 2973 R PGPP GPPGPP G G +GEPG PG G+PG PG PG Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317 Query: 2974 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 3009 G PGE G GEKG++G TG GP GLPG PG +GE Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377 Query: 3010 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 3042 GPPG G GPPGPPG PG G +G GPPG Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415 Score = 231 bits (588), Expect = 1e-59 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GP G PG G PG +G G GI G IGPPGP G +GPPGP G PGP+G GL+ G +G Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227 Query: 2807 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 2849 +G +G G PG PG+ G GLPG GP GPPG RG G + G Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 2909 G +G PG G PG G G G PG PGD G PG G GEKG +GD V Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 2910 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 2956 + + G+ L +P + Q PGPPG PPGPPG G R Sbjct: 348 RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 2957 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 3003 G+ G G PG PG PG+ G PG GLPG G G G GP G PG Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 3004 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 3046 G QGE +GPPG G G PGPPG G G +G G G Sbjct: 466 GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525 Query: 3047 SQCASIP--YNGQGYPGS 3062 IP G+PGS Sbjct: 526 KGLPGIPGAPGAPGFPGS 543 Score = 230 bits (587), Expect = 1e-59 Identities = 146/342 (42%), Positives = 166/342 (48%), Gaps = 38/342 (11%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 S+G PG PGP G PG G G GI G++G PG G G PG +G PG G G PG Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 2855 G +G+ G G PGLPG G G G PG GPPG++G G+DG GP G Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 2856 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913 PGPPG PG G G G PG PG+ G PGP KGE G G Q Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSP--G 1244 Query: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 2973 + G N P PGP GPPG PG+ G +GE G G+PG PG PG+ Sbjct: 1245 PALEGPKG------NPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298 Query: 2974 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 3025 QGPPG +G PG G G G G G+PG PG +G S GP G G GPPGP Sbjct: 1299 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358 Query: 3026 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 3061 PG PG SG I+G GPPG + P QG PG Sbjct: 1359 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1400 Score = 223 bits (568), Expect = 2e-57 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 2804 G PG PGP G G G +GE+G +GA GP G G G PG G PG +G G L+ PG Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 MKGD GE G PG G PGLPG PG G PG G G+ G + +G GPPG+PG Sbjct: 556 -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610 Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 2918 PG+ G G G PG G PGP G KG +G G+ + Q + + G Sbjct: 611 PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669 Query: 2919 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 2965 R + +P D S+ +PG P G PGPPG G G PGP G P Sbjct: 670 NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727 Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 3007 G PG G++GPPG G PG KGE G G G RG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787 Query: 3008 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 3042 + GP G G G PGP G PG G++GPPGPPG Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828 Score = 219 bits (557), Expect = 4e-56 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 2800 G PG PGP G PG +GERG G G PG G+IGP GP G PPGP G G+ Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 2801 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 2848 PG+ G G KGD G+ PG PGR G GLPG PG G PG G G G Sbjct: 642 NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701 Query: 2849 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905 +G GPPGP G PG PG G G PG+ G G PGP G G KG+ G Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753 Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 2956 A+ + G F L + R PGPPGPPG P G G Sbjct: 754 ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 2957 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 3015 G+PGP G PG PG G+QGPPG G+PG G+ G G G +G PGPPG PG Sbjct: 805 GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857 Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 G RG PG PG PG G G PG PG +S G+PG+ Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894 Score = 218 bits (555), Expect = 7e-56 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%) Query: 2747 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 2792 GPPGPPG G PG KG +GE+G G G PG G+ G PG G PG Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 2793 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830 P GP GL IP G G G+ G+ GE G PG G PGLPG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386 Query: 2831 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 2872 PPG MGPPG GF G+ G G GPPG PG+PG PG GP+G Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446 Query: 2873 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 2927 +PG PG G PG GL+GE+G +GD C I ++ Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490 Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 2975 PG PG PG PG G+ G P GP G PG PG PG G Sbjct: 491 -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539 Query: 2976 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 3015 PG +G P G+KGE G+ G+ G GLPG PGP+GE P G Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595 Query: 3016 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 3043 T G RGPPG PG PG G GP GPPG+ Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625 Score = 215 bits (548), Expect = 5e-55 Identities = 126/287 (43%), Positives = 140/287 (48%), Gaps = 46/287 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP--GPQGPPGPQGPNGL-SIPG 2803 G PG PG G PG KG G G G GPPGP G GP GP+G PGPQGP G +PG Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPG 1267 Query: 2804 EQGRQGMKGDAG---EPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPG 2860 +G G+ G+ G E G PG+ G PGLPG G GPPG +G G+ G G +G PG PG Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1327 Query: 2861 SPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQM 2920 PG PG+ GPSG PG G G PG G G G Sbjct: 1328 VPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG--------------------------- 1360 Query: 2921 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 2980 +P S G GPPG PG G +G PGP G G PG G G PG Sbjct: 1361 ---------LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN 1411 Query: 2981 GLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPG 3027 GLPG G G G GLPG PG +G GPPG G +GPPGPPG Sbjct: 1412 GLPGFDG--AGGRKGDPGLPGQPGTRG--LDGPPGPDGLQGPPGPPG 1454 Score = 209 bits (532), Expect = 3e-53 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 2763 P FP S D + PG G G PG GP Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597 Query: 2764 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 2816 +GERG G G PG G+IGP GP GPPGP G G+ PG+ G G KGD G+ Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 2817 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 2861 PG PGR G GLPG PG G PG G G G +G GPPGP G Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717 Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921 PG PG G G PG+ G G PGP G G KG+ G A+ + G Sbjct: 718 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766 Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 2972 F L + R PGPPGP PGP G G G+PGP G PG PG G Sbjct: 767 -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819 Query: 2973 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 3025 +QGPPG G+PG G+ G G G +G PGP PGP GE G PG+ G GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 3026 PGRPGNS------------GIRGPPGPPG 3042 PG PG + G+ GPPGPPG Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 204 bits (520), Expect = 8e-52 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%) Query: 2745 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 2795 ++GP GPPG P G G KG +G G G G PGP+GD G PG G PG G Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 2796 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 2833 GL +PG+ G G+ G GEPG+PG G PG+PGPPG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 2834 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 2874 P GPPG G G GA+GP+G G PG PG PG TG G P Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 2875 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931 G GD +G+PGP G G G I Q I G + + L+ IP Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842 Query: 2932 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989 + + PGPPG PGPPG G+ G PG G G PG+PG+ G G G PG KGE Sbjct: 843 GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898 Query: 2990 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 3042 G G PGPPGP G R+G PG G G G PG PG +G +G PGPPG Sbjct: 899 GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 3043 YCDSSQCASIPYNGQ-GYPG 3061 D + S G+ G PG Sbjct: 954 PMDPNLLGSKGEKGEPGLPG 973 Score = 139 bits (349), Expect = 6e-32 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G PG PG G PG KGP G + G+ GP G G IGPPGP G PGP G + + I G+ G Sbjct: 1321 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1376 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866 G+ G G GLPG G GLPGP GP G PG G G DGA G +G PG PG PG+ G Sbjct: 1377 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1436 Query: 2867 VTGPSGKPGKPGDHGRPGPSGL 2888 + GP G G G G PG S + Sbjct: 1437 LDGPPGPDGLQGPPGPPGTSSV 1458 Score = 105 bits (263), Expect = 5e-22 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000 PGP GPPGP G G G PGP G G G PG+ G PG GLPG G G+ GP+G+P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122 Query: 3001 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 3050 G G +GE G PG G +GPPGPPG PG G + GP G PGY Sbjct: 123 GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182 Query: 3051 SIPYNGQGYPG 3061 +P G PG Sbjct: 183 GLP-GPTGIPG 192 Score = 90.9 bits (224), Expect = 2e-17 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007 G G G RG PG G PG PG PG +GPPG RG G+ G G GP+G+ GPPG G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99 Query: 3008 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043 T G PG G+ GP G PG G G RG PG PG+ Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Score = 75.1 bits (183), Expect = 1e-12 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%) Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 2997 G P A A PG + G G +G G GL G G G G GPR Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 2998 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 3057 G+PGPPGP+G GPPG G G PG PG PG+ G GP G PG C+ ++ + Sbjct: 81 GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131 Query: 3058 GYPGS 3062 G+PGS Sbjct: 132 GFPGS 136 Score = 60.8 bits (146), Expect = 2e-08 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800 GPPG PG G PG G G +G G G PG RG GPPGP QGPPGP G + ++ Sbjct: 1403 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459 Score = 57.8 bits (138), Expect = 2e-07 Identities = 31/64 (48%), Positives = 32/64 (50%), Gaps = 6/64 (9%) Query: 2743 QDSVGPPGPPGPAGGPGAK------GPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 2796 Q G PGP GP G PG G G +G G G PG RG GPPGP G GP GP Sbjct: 1393 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1452 Query: 2797 NGLS 2800 G S Sbjct: 1453 PGTS 1456 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 253 bits (647), Expect = 2e-66 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 2792 GPPGPPG G GA GP+G+RG G GPPG P+GD+GP PGP GPPG Sbjct: 757 GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816 Query: 2793 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 2837 P GP G+ PG G G KGD G PGL PG G+PG+PG PGP+GP Sbjct: 817 GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 2838 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885 PG G GK GA MGP GPPGP G PG GV G G G G G PGP Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 2935 +G KG KG+ G + + L+ + + L I P YQ Sbjct: 937 TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989 Query: 2936 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 2976 QPG PGPPGP G+ G G+PG PG G GFPG G++GP Sbjct: 990 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049 Query: 2977 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 3029 PG GLPG+KG++G GLPG PGP+GE G PG GS G PG PG P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 3030 GNSGIRGPPGPPGY 3043 G G +G PG PG+ Sbjct: 1110 GTPGAKGQPGLPGF 1123 Score = 246 bits (629), Expect = 2e-64 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%) Query: 2746 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799 +GPPGPPGP +G PG KG G +G G GP G +G G PG GPPGP PN L Sbjct: 901 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960 Query: 2800 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 2838 IPG G +G +G G+PG PG +G PGLPGPPGP G P Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 2839 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 2887 GD GF G G GP GP G PG PGSPG+ G G G PG G PG G Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080 Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 2946 KGE G G + + +V L + L P PGPPGP Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133 Query: 2947 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 2995 GPPG+ G GEPGP GG PG PG PG +G PG+ G+P GE G+ G G+ G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 2996 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 P GLPG G +G+ G PG+ G GP G PG G G++GPPGPPG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Score = 238 bits (606), Expect = 9e-62 Identities = 156/375 (41%), Positives = 185/375 (49%), Gaps = 59/375 (15%) Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 2782 +P + E P +P + + SVG PG PG G PGAKG G G G GPPGP+G Sbjct: 1078 LPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136 Query: 2783 GPPGPQGPPGPQGPNG-------LSIPGEQGRQGM---------KGDAGEPG-------- 2818 GPPG G PG GP G PGE+G+ G KG+ G+PG Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196 Query: 2819 ---LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP-----GSPGVTGP 2870 L G+ G GLPG PG G PG +G G G G +GPPGPPGSP G G GP Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256 Query: 2871 SGKPGKPGDHGRPGP---------SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921 G PG+PG G PGP G+KGEKG+ G + Q L Q N Sbjct: 1257 QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL---QGN 1313 Query: 2922 RFNQMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG------- 2972 LN + D PG GP G PGSAG GEPG G PG PG PG Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1373 Query: 2973 MQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPP---GSTGSRGPPGPPG 3027 ++G G G+PG+ G +G G GP+GLPGP GP G+ R G P G+ G +G PG PG Sbjct: 1374 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1433 Query: 3028 RPGNSGIRGPPGPPG 3042 +PG G+ GPPGP G Sbjct: 1434 QPGTRGLDGPPGPDG 1448 Score = 237 bits (604), Expect = 2e-61 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 2800 +G PGPPGP G PG GP G G G IG GP G G PGP+G PGP GP GL Sbjct: 706 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764 Query: 2801 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 2843 PG +G G KGD G PG PGRTG GLPGP PGPMGPPG G Sbjct: 765 -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823 Query: 2844 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 2880 G G G +G PGPP GSPG PG GP G PG PG Sbjct: 824 PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883 Query: 2881 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938 G+ G SG G KG+ G + + + + G Q P + S+ Sbjct: 884 GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 2939 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 2996 +PG PGPPGP P G++GE G PG PG PG+ GP G +GLPG+ G+ G SG Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998 Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 3042 GLPGPPGP+G G PG G GPPG G PG G+ GPPGP G Sbjct: 999 PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048 Score = 236 bits (601), Expect = 3e-61 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%) Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 2798 D + PGPPGP G PG KG +GE+G+ G G G GPPG G PG GP G Sbjct: 448 DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507 Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 2857 L PG++G +G G G GLPG G PG PG PG G PGD F G G G G PG Sbjct: 508 LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567 Query: 2858 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917 PG PG PG G G PG PG G PG KGE+G G+ + + Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617 Query: 2918 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 2965 G M F Q PG PG PGP PG G G PG G Sbjct: 618 GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677 Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019 G PG PG+ G PG G+PG KGE G G GP+G PG PGP G G PG G Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735 Query: 3020 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GPPGPPG PG G + GPPGPPG + A P +G+PG Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781 Score = 234 bits (596), Expect = 1e-60 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%) Query: 2710 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 2769 CSP S+ C I + E P + G PG PGP G PG PRG++G Sbjct: 32 CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79 Query: 2770 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 2825 G GPPGP+G GPPG G PG G G+ PG QG G G GE G PG G Sbjct: 80 DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Query: 2826 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 2876 PGL GPPGP G PG +G G G G GPPG G PG G+ GP G PG Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 2877 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 2935 PG G PGP GL G KG+ G + Q Q Q G + ++ I ++Q Sbjct: 200 PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257 Query: 2936 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 2973 R PGPP GPPGPP G G +GEPG PG G+PG PG PG Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317 Query: 2974 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 3009 G PGE G GEKG++G TG GP GLPG PG +GE Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377 Query: 3010 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 3042 GPPG G GPPGPPG PG G +G GPPG Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415 Score = 231 bits (588), Expect = 1e-59 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GP G PG G PG +G G GI G IGPPGP G +GPPGP G PGP+G GL+ G +G Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227 Query: 2807 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 2849 +G +G G PG PG+ G GLPG GP GPPG RG G + G Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287 Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 2909 G +G PG G PG G G G PG PGD G PG G GEKG +GD V Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 2910 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 2956 + + G+ L +P + Q PGPPG PPGPPG G R Sbjct: 348 RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405 Query: 2957 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 3003 G+ G G PG PG PG+ G PG GLPG G G G GP G PG Sbjct: 406 GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 3004 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 3046 G QGE +GPPG G G PGPPG G G +G G G Sbjct: 466 GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525 Query: 3047 SQCASIP--YNGQGYPGS 3062 IP G+PGS Sbjct: 526 KGLPGIPGAPGAPGFPGS 543 Score = 230 bits (586), Expect = 2e-59 Identities = 146/342 (42%), Positives = 167/342 (48%), Gaps = 35/342 (10%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 S+G PG PGP G PG G G GI G++G PG G G PG +G PG G G PG Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 2855 G +G+ G G PGLPG G G G PG GPPG++G G+DG GP G Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 2856 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913 PGPPG PG G G G PG PG+ G PGP KGE G G Q Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSP--G 1244 Query: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 2973 + G Q P + PGP GPPG PG+ G +GE G G+PG PG PG+ Sbjct: 1245 PALEGPKGNPGP---QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301 Query: 2974 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 3025 QGPPG +G PG G G G G G+PG PG +G S GP G G GPPGP Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361 Query: 3026 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 3061 PG PG SG I+G GPPG + P QG PG Sbjct: 1362 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1403 Score = 223 bits (568), Expect = 2e-57 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 2804 G PG PGP G G G +GE+G +GA GP G G G PG G PG +G G L+ PG Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 MKGD GE G PG G PGLPG PG G PG G G+ G + +G GPPG+PG Sbjct: 556 -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610 Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 2918 PG+ G G G PG G PGP G KG +G G+ + Q + + G Sbjct: 611 PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669 Query: 2919 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 2965 R + +P D S+ +PG P G PGPPG G G PGP G P Sbjct: 670 NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727 Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 3007 G PG G++GPPG G PG KGE G G G RG PGPPGP G Sbjct: 728 GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787 Query: 3008 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 3042 + GP G G G PGP G PG G++GPPGPPG Sbjct: 788 RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828 Score = 219 bits (557), Expect = 4e-56 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 2800 G PG PGP G PG +GERG G G PG G+IGP GP G PPGP G G+ Sbjct: 582 GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641 Query: 2801 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 2848 PG+ G G KGD G+ PG PGR G GLPG PG G PG G G G Sbjct: 642 NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701 Query: 2849 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905 +G GPPGP G PG PG G G PG+ G G PGP G G KG+ G Sbjct: 702 GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753 Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 2956 A+ + G F L + R PGPPGPPG P G G Sbjct: 754 ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804 Query: 2957 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 3015 G+PGP G PG PG G+QGPPG G+PG G+ G G G +G PGPPG PG Sbjct: 805 GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857 Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 G RG PG PG PG G G PG PG +S G+PG+ Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894 Score = 218 bits (555), Expect = 7e-56 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%) Query: 2747 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 2792 GPPGPPG G PG KG +GE+G G G PG G+ G PG G PG Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326 Query: 2793 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830 P GP GL IP G G G+ G+ GE G PG G PGLPG Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386 Query: 2831 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 2872 PPG MGPPG GF G+ G G GPPG PG+PG PG GP+G Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446 Query: 2873 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 2927 +PG PG G PG GL+GE+G +GD C I ++ Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490 Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 2975 PG PG PG PG G+ G P GP G PG PG PG G Sbjct: 491 -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539 Query: 2976 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 3015 PG +G P G+KGE G+ G+ G GLPG PGP+GE P G Sbjct: 540 FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595 Query: 3016 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 3043 T G RGPPG PG PG G GP GPPG+ Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625 Score = 211 bits (536), Expect = 1e-53 Identities = 129/312 (41%), Positives = 144/312 (46%), Gaps = 67/312 (21%) Query: 2743 QDSVGPPGP---------------PGPAGGPGAKGPRGE---RGISGAIGPPGPRGDIGP 2784 Q G PGP PG G PG GP+GE G G GPPGP G GP Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245 Query: 2785 --PGPQGPPGPQGPNG----LSIPGEQGRQGMKGDA---GEPGLPGRTGTPGLPGPPGPM 2835 GP+G PGPQGP G +PG +G G+ G+ GE G PG+ G PGLPG G Sbjct: 1246 ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305 Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895 GPPG +G G+ G G +G PG PG PG PG+ GPSG PG G G PG G G G Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG-- 1363 Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGA 2955 +P S G GPPG PG G Sbjct: 1364 ----------------------------------LPGPSGQSIIIKGDAGPPGIPGQPGL 1389 Query: 2956 RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPG 3015 +G PGP G G PG G G PG GLPG G G G GLPG PG +G GPPG Sbjct: 1390 KGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG--AGGRKGDPGLPGQPGTRG--LDGPPG 1445 Query: 3016 STGSRGPPGPPG 3027 G +GPPGPPG Sbjct: 1446 PDGLQGPPGPPG 1457 Score = 209 bits (532), Expect = 3e-53 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 2763 P FP S D + PG G G PG GP Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597 Query: 2764 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 2816 +GERG G G PG G+IGP GP GPPGP G G+ PG+ G G KGD G+ Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657 Query: 2817 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 2861 PG PGR G GLPG PG G PG G G G +G GPPGP G Sbjct: 658 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717 Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921 PG PG G G PG+ G G PGP G G KG+ G A+ + G Sbjct: 718 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766 Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 2972 F L + R PGPPGP PGP G G G+PGP G PG PG G Sbjct: 767 -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819 Query: 2973 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 3025 +QGPPG G+PG G+ G G G +G PGP PGP GE G PG+ G GPPG Sbjct: 820 VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879 Query: 3026 PGRPGNS------------GIRGPPGPPG 3042 PG PG + G+ GPPGPPG Sbjct: 880 PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908 Score = 204 bits (520), Expect = 8e-52 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%) Query: 2745 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 2795 ++GP GPPG P G G KG +G G G G PGP+GD G PG G PG G Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675 Query: 2796 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 2833 GL +PG+ G G+ G GEPG+PG G PG+PGPPG Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735 Query: 2834 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 2874 P GPPG G G GA+GP+G G PG PG PG TG G P Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795 Query: 2875 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931 G GD +G+PGP G G G I Q I G + + L+ IP Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842 Query: 2932 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989 + + PGPPG PGPPG G+ G PG G G PG+PG+ G G G PG KGE Sbjct: 843 GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898 Query: 2990 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 3042 G G PGPPGP G R+G PG G G G PG PG +G +G PGPPG Sbjct: 899 GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953 Query: 3043 YCDSSQCASIPYNGQ-GYPG 3061 D + S G+ G PG Sbjct: 954 PMDPNLLGSKGEKGEPGLPG 973 Score = 139 bits (349), Expect = 6e-32 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G PG PG G PG KGP G + G+ GP G G IGPPGP G PGP G + + I G+ G Sbjct: 1324 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1379 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866 G+ G G GLPG G GLPGP GP G PG G G DGA G +G PG PG PG+ G Sbjct: 1380 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1439 Query: 2867 VTGPSGKPGKPGDHGRPGPSGL 2888 + GP G G G G PG S + Sbjct: 1440 LDGPPGPDGLQGPPGPPGTSSV 1461 Score = 105 bits (263), Expect = 5e-22 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000 PGP GPPGP G G G PGP G G G PG+ G PG GLPG G G+ GP+G+P Sbjct: 65 PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122 Query: 3001 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 3050 G G +GE G PG G +GPPGPPG PG G + GP G PGY Sbjct: 123 GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182 Query: 3051 SIPYNGQGYPG 3061 +P G PG Sbjct: 183 GLP-GPTGIPG 192 Score = 90.9 bits (224), Expect = 2e-17 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007 G G G RG PG G PG PG PG +GPPG RG G+ G G GP+G+ GPPG G Sbjct: 42 GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99 Query: 3008 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043 T G PG G+ GP G PG G G RG PG PG+ Sbjct: 100 FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139 Score = 75.1 bits (183), Expect = 1e-12 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%) Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 2997 G P A A PG + G G +G G GL G G G G GPR Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80 Query: 2998 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 3057 G+PGPPGP+G GPPG G G PG PG PG+ G GP G PG C+ ++ + Sbjct: 81 GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131 Query: 3058 GYPGS 3062 G+PGS Sbjct: 132 GFPGS 136 Score = 60.8 bits (146), Expect = 2e-08 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800 GPPG PG G PG G G +G G G PG RG GPPGP QGPPGP G + ++ Sbjct: 1406 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462 >gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo sapiens] Length = 678 Score = 253 bits (647), Expect = 2e-66 Identities = 148/353 (41%), Positives = 177/353 (50%), Gaps = 45/353 (12%) Query: 2742 TQDSVGPPGPPGPAGG---------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 T+ G PGPPG AG PGAKG GE+G +GA G PG G+ G PG QGPPG Sbjct: 311 TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 370 Query: 2793 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--------------- 2836 GP G +PG +G G G G PG G G+PGLPG PGP G Sbjct: 371 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 430 Query: 2837 PPGDRGFTGKDGAMGPRGP------PGPPGS---PGSPGVTGPSGKPGKPGDHGRPGPSG 2887 P G++G +G++G G RG PGP GS PG PG+ GP G G PG G GP G Sbjct: 431 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490 Query: 2888 LKGEKGDRGDIASQNMMRAVAR--------QVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939 +G +G++G + R QVC ++I L + + Sbjct: 491 PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550 Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGL 2999 +PGPPGPPGPPG G G+ G G PG G PG G G +G GEKGERG GP GL Sbjct: 551 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGL 610 Query: 3000 PGP---PGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQC 3049 PG PG G + G G G RGPPG G PG G GPPG PG+C+ + C Sbjct: 611 PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 663 Score = 241 bits (614), Expect = 1e-62 Identities = 139/328 (42%), Positives = 170/328 (51%), Gaps = 38/328 (11%) Query: 2739 CTCTQDSVGPPGPPGPAGGPGA---KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 2795 C + G GPPGP G PG G G+RG G GPPGP G+ G PG G PG G Sbjct: 21 CAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 80 Query: 2796 PNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTP--GLPGPPGPMGP---PGDRGFTGKDGA 2849 +GL+ P G G G KG GEPG+PG G P G+PGPPGP G PG+ G G G Sbjct: 81 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGD 140 Query: 2850 MGPRGPPGPPGSPGSPGVTG--------PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQ 2901 G RGPPGPPG PG G G P+ P PG G PG G++G KG +G+I Sbjct: 141 PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP--PGRSGYPGLPGMRGHKGAKGEIGEP 198 Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961 + G ++ Q P Q R G G G G+ G GEPGP Sbjct: 199 GRQGHKGEE-------GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251 Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGES-------RTGPP 3014 G PG PG G +GPPGE G G++ G+ G RG+PG PGP+G++ R G P Sbjct: 252 QGLPGAPGDQGQRGPPGEAGPKGDR-----GAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306 Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G G++G PG PG PG++G++G PG PG Sbjct: 307 GMPGTKGEPGKPGPPGDAGLQGLPGVPG 334 Score = 232 bits (591), Expect = 5e-60 Identities = 149/358 (41%), Positives = 174/358 (48%), Gaps = 41/358 (11%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 P PN+C + G PG PG G GAKG GE G G G G +G++G G QGPPG Sbjct: 166 PLCPNACPPGRS--GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 223 Query: 2793 PQGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK-- 2846 QG G++ GE+G +G+ G+ G GLPG G G GPPG GP GDRG G Sbjct: 224 AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 283 Query: 2847 -DGAMGPRGPPGPPGS------PGSPGVTGPSGKPGKPGDHGR---------PGPSGLKG 2890 G GP+G G PG PG PG G GKPG PGD G PG G+ G Sbjct: 284 IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG 343 Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950 EKG G M + GQ ++ + P SR + GP G PG P Sbjct: 344 EKGSTGAPGKPGQMGNSGKP-------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 396 Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPRGLPGP---P 3003 G G+ G PG G PG PG PGM+G G G PG KGE+G G +G RG G P Sbjct: 397 GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 456 Query: 3004 GPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 GP+G + G PG G RGP G G PG G RGPPGP G +P QG PG Sbjct: 457 GPKGSA--GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP-GVQGPPG 511 Score = 212 bits (539), Expect = 5e-54 Identities = 148/393 (37%), Positives = 168/393 (42%), Gaps = 101/393 (25%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---PRGDIG------------------PP 2785 G PG G G PG GP+G+RG GA G PG P+GD G P Sbjct: 256 GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315 Query: 2786 GPQGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844 G GPPG G GL +PG G +G+ G+ G G PG+ G G G PG GPPG+ G Sbjct: 316 GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375 Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 2904 G G G RG GP GSPG PG G G PG PG PGP GL G KGDRG + Sbjct: 376 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPK 432 Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG---P 2961 EQ SG+ + R + G G PGP GSAG GEPG P Sbjct: 433 G-------EQGASGEEGEAGE------------RGELGDIGLPGPKGSAGNPGEPGLRGP 473 Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG------------------------------- 2990 G G PG G +GPPG RG+ GE+G G Sbjct: 474 EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533 Query: 2991 ------------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGP- 3037 TG G G PGPPGP GE+ G PG G RG PG G PG G+RGP Sbjct: 534 MAASLKRPDSGATGLPGRPGPPGPPGPPGEN--GFPGQMGIRGLPGIKGPPGALGLRGPK 591 Query: 3038 --------PGPPGYCDSSQCASIPYNGQGYPGS 3062 GPPG + +I G P S Sbjct: 592 GDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 624 Score = 107 bits (268), Expect = 1e-22 Identities = 79/245 (32%), Positives = 90/245 (36%), Gaps = 95/245 (38%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL------ 2799 VG PGP G G G +G GERG G IG PGP+G G PG G GP+G GL Sbjct: 426 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 485 Query: 2800 -------SIPGEQGRQGMKGDAGEPGLP------------------------------GR 2822 + GEQG G+ G G PG G Sbjct: 486 RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545 Query: 2823 TGTPGLPGPPGPMGPPGDRGFTGK------------DGAMGPRGPPG---------PPGS 2861 TG PG PGPPGP GPPG+ GF G+ GA+G RGP G PPG Sbjct: 546 TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 605 Query: 2862 -------------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890 PG G+ G G PG PG G P+ Sbjct: 606 GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 665 Query: 2891 EKGDR 2895 + G R Sbjct: 666 QAGQR 670 Score = 84.3 bits (207), Expect = 2e-15 Identities = 51/121 (42%), Positives = 60/121 (49%), Gaps = 25/121 (20%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG------PRGDIGPPGPQGPPGPQGPNGL- 2799 GPPGPPGP G G G G RG+ G GPPG P+GD+G G +GPPG +GPNGL Sbjct: 553 GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 611 Query: 2800 ---SIPGEQG-----RQGMKGDAGEPGL---------PGRTGTPGLPGPPGPMGPPGDRG 2842 +PG+ G R G G+ G PG+ PG G PG P G R Sbjct: 612 GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 671 Query: 2843 F 2843 F Sbjct: 672 F 672 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 252 bits (644), Expect = 3e-66 Identities = 152/361 (42%), Positives = 173/361 (47%), Gaps = 34/361 (9%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792 PA P G PGPPGPAG G G G+ G G G G +GD GPPGP GP G Sbjct: 789 PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848 Query: 2793 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMG 2851 P GP G + PG +G +G G G G PG G G PGP G GPPG G GK+G G Sbjct: 849 PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908 Query: 2852 PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQV 2911 PRG GP G PG G GP G G+ G G GP+G G G +G IA Q + + Q Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG-IAGQRGVVGLPGQR 967 Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---PPGSAGARGEPGPGGRPGFP 2968 E+ G + Q P+ R PGP GPPG PPG +G G PG G PG Sbjct: 968 GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD 1027 Query: 2969 GTPGMQG---------PPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTG 3018 G+PG +G PPG G PG G G G SG RG GP GP G GP G+ G Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP--VGPVGARG 1085 Query: 3019 SRGPPGPPGRPGN---------------SGIRGPPGPPGYC--DSSQCASIPYNGQGYPG 3061 GP GP G G SG++GPPGPPG AS P +G PG Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPG 1145 Query: 3062 S 3062 S Sbjct: 1146 S 1146 Score = 250 bits (638), Expect = 2e-65 Identities = 151/361 (41%), Positives = 177/361 (49%), Gaps = 59/361 (16%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G PGPPG GGPG++G G G++G GP G RG GP GP+G PG G PGE G Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR-----PGEAG 533 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGP------PGPMGPPGDRGFTGKDGAMGPRGPPGPPG 2860 G KG G PG PG G G PGP PGP GPPG RG G G GP+G G PG Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593 Query: 2861 S------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR--------A 2906 PG PG GP+GK G+ G G PGP+G GE+G++G S Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653 Query: 2907 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP------PGSAGARGEPG 2960 A + EQ + G + + + R GPPGP GP PG+ GA+G+ G Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713 Query: 2961 PGGRPGFPGTPGMQGPPGERG---LPGEKGERGT----------GSSGPRGLPGPPGPQG 3007 G PG G PG+QG PGERG LPG KG+RG G G RGL GP GP G Sbjct: 714 APGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773 Query: 3008 ESRTGPPGSTGSRGPPGPPG------RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061 + G PG G GP GP G PG+ G GPPGP G+ P G PG Sbjct: 774 PA--GAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG-------PPGADGQPG 824 Query: 3062 S 3062 + Sbjct: 825 A 825 Score = 248 bits (634), Expect = 5e-65 Identities = 142/314 (45%), Positives = 159/314 (50%), Gaps = 36/314 (11%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804 + GPPGPPGPAG G KGPRGE G +G G GP G GP G +G PG GP G PG Sbjct: 891 NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGA--PGT 948 Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864 G QG+ G G GLPG+ G G PG PGP G PG + G GA G RGPPGP G PG Sbjct: 949 PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ---GPSGASGERGPPGPMGPPGL 1005 Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924 G G SG+ G PG G PG G G KGDRG+ A + Sbjct: 1006 AGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG------- 1058 Query: 2925 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR---------------PGFPG 2969 P R + GP GP GP G GARG GP G G G Sbjct: 1059 ------PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRG 1112 Query: 2970 TPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGR 3028 G+QGPPG G PGE+G +G+SGP G GPPG G + G G G GPPGP GR Sbjct: 1113 FSGLQGPPGPPGSPGEQGP--SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170 Query: 3029 PGNSGIRGPPGPPG 3042 G++G GPPGPPG Sbjct: 1171 TGDAGPVGPPGPPG 1184 Score = 248 bits (633), Expect = 7e-65 Identities = 147/351 (41%), Positives = 170/351 (48%), Gaps = 41/351 (11%) Query: 2724 PSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIG 2783 P+ +D P P +G PGP G AG PG G RG G GA+GP G G+ G Sbjct: 558 PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAG 617 Query: 2784 PPGPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPG 2839 GP GP GP G G PG QG G G GE G PG G PG G PGP G G Sbjct: 618 AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARG 677 Query: 2840 DRGFTGKDGAMGPRGPPGP---PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE----- 2891 +RGF G+ G GP GP GP G+PG+ G G +G PG PG G PG G+ GE Sbjct: 678 ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737 Query: 2892 ----KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 2947 KGDRGD + + + G + P + + GP GP Sbjct: 738 LPGPKGDRGDAGPKGADGSPGK-------DGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790 Query: 2948 GPPGSAGA---RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP 3003 GP G+ GA RGEPGP G GF G PG G PG +G PG+ G +G G GP G GPP Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850 Query: 3004 GPQGESRTGPPGSTGSRGPPGPPGR------------PGNSGIRGPPGPPG 3042 GP G G PG+ G+RG GPPG PG SG GPPGPPG Sbjct: 851 GPIG--NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG 899 Score = 248 bits (632), Expect = 9e-65 Identities = 157/387 (40%), Positives = 173/387 (44%), Gaps = 95/387 (24%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG------------PGAKGPRGERGISGAIGPPGPRG 2780 P P Q G PGPPGPAG PGAKG G GI+GA G PG RG Sbjct: 357 PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416 Query: 2781 DIGPPGPQGPPGPQGPNG-------------LSIPGEQGRQGMKGDAGEPGLPGRTGTPG 2827 GP GP GPPGP+G +G PG G QG G AGE G G G PG Sbjct: 417 PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG 476 Query: 2828 ---LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPG 2884 LPGPPG G PG RGF G DG GP+GP G GSPG G G G+ G+PG+ G PG Sbjct: 477 PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPG 536 Query: 2885 PSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPP 2944 GL G G G P +PGPP Sbjct: 537 AKGLTGSPGSPGPDGKTG----------------------------PPGPAGQDGRPGPP 568 Query: 2945 GPPGP---------PGSAGARGEPGPGGRPGFPGTP------------GMQGPPGERGLP 2983 GPPG PG GA GEPG G G PG P G QGPPG G Sbjct: 569 GPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628 Query: 2984 GEKGERG-TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGR------PGNSGIR 3035 GE+GE+G GS G +GLPGP GP GE+ + G G G G PGP G PG G++ Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688 Query: 3036 GPPGPPGYCDSSQCASIPYNGQGYPGS 3062 GPPGP G P G PG+ Sbjct: 689 GPPGPAG----------PRGANGAPGN 705 Score = 243 bits (620), Expect = 2e-63 Identities = 135/297 (45%), Positives = 151/297 (50%), Gaps = 51/297 (17%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GP GPPGPAG PG KG SG GP GP G G PG +G PGP GP G + G G Sbjct: 767 GPIGPPGPAGAPGDKGE------SGPSGPAGPTGARGAPGDRGEPGPPGPAGFA--GPPG 818 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866 G G GEPG G G G PGP GP GPPG G G GA G RG GPPG+ G PG Sbjct: 819 ADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPG 878 Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926 G G PG G+ G PGP G G++G +G Sbjct: 879 AAGRVGPPGPSGNAGPPGPPGPAGKEGGKG------------------------------ 908 Query: 2927 LNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEK 2986 P +PG GPPGPPG AG +G PG G G PGTPG QG G+RG+ G Sbjct: 909 ----PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964 Query: 2987 GERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G+R G RG PG PGP GE + GP G++G RGPPGP G P G+ GPPG G Sbjct: 965 GQR-----GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP---GLAGPPGESG 1013 Score = 239 bits (609), Expect = 4e-62 Identities = 142/331 (42%), Positives = 164/331 (49%), Gaps = 46/331 (13%) Query: 2747 GPPGPPGPAG----------------------GPGAKGPRGERGISGAIGPPGPRGDIGP 2784 GPPGPPGP G PG GP G RG+ G G PGP+G GP Sbjct: 145 GPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP 204 Query: 2785 PGPQGPPGPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPG------LPGPPGPMGP 2837 PG G PG GP G PG G+ G G+AG+PG PG G PG LPG G G Sbjct: 205 PGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGM 264 Query: 2838 PGDRGFTGKDGAMG---PRGPPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891 G RGF+G DGA G P GP G PGSP G+PG GP G PG+ G G PGP+G +G Sbjct: 265 KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324 Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951 G G G + + Q P + + G PGPPGP G Sbjct: 325 DGATGAAGPPGPTGPAG----PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG 380 Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRT 3011 +AG G PG G+ PG G G PG G PG G R G SGP+G GPPGP+G S Sbjct: 381 AAGPAGNPGADGQ---PGAKGANGAPGIAGAPGFPGAR--GPSGPQGPGGPPGPKGNS-- 433 Query: 3012 GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G PG+ GS+G G G PG G++GPPGP G Sbjct: 434 GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464 Score = 238 bits (607), Expect = 7e-62 Identities = 141/319 (44%), Positives = 161/319 (50%), Gaps = 64/319 (20%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS---- 2800 + GPPGP GPAG PG G G +G +G P GPRG GP G +G PGP GP G + Sbjct: 330 AAGPPGPTGPAGPPGFPGAVGAKGEAG---PQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386 Query: 2801 IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM---GPPGDRGFTGKDGAMGPRGPPG 2857 PG G+ G KG G PG+ G G PG GP GP GPPG +G +G+ GA G +G G Sbjct: 387 NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG 446 Query: 2858 PPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914 G PG GV GP+G+ GK G G PGP+GL G G+RG Sbjct: 447 AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG----------------- 489 Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 2974 SR PG G GP G AG RG PGP G G+PG Sbjct: 490 --------------------PGSRGFPGADGVAGPKGPAGERGSPGPAGP---KGSPGEA 526 Query: 2975 GPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG-ESRTGPPGSTGSR---------GPP 3023 G PGE GLPG KG G+ GS GP G GPPGP G + R GPPG G+R GP Sbjct: 527 GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK 586 Query: 3024 GPPGRPGNSGIRGPPGPPG 3042 G G PG +G RG PGPPG Sbjct: 587 GAAGEPGKAGERGVPGPPG 605 Score = 225 bits (573), Expect = 6e-58 Identities = 136/333 (40%), Positives = 154/333 (46%), Gaps = 55/333 (16%) Query: 2724 PSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAG------------GPGAKGPRGERGISG 2771 P+ ++ GK P VGPPGPPGPAG PG GP+G G G Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959 Query: 2772 AIGPPGPRGDIG---PPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGL 2828 +G PG RG+ G PGP G PG QGP+G S GE+G G G G G PG +G G Sbjct: 960 VVGLPGQRGERGFPGLPGPSGEPGKQGPSGAS--GERGPPGPMGPPGLAGPPGESGREGA 1017 Query: 2829 PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888 PG G G G G G G GP GPPG PG+PG+PG GP+GK G G+ G GP+G Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077 Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948 G G RG Q P + + G G G Sbjct: 1078 VGPVGARGPAGPQG----------------------------PRGDKGETGEQGDRGIKG 1109 Query: 2949 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE 3008 G +G +G PGP G PG G G GP G RG PG G G G GLPGP GP Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG--APGKDGLNGLPGPIGP--- 1164 Query: 3009 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041 GP G TG GP GPPG PG GPPGPP Sbjct: 1165 --PGPRGRTGDAGPVGPPGPPGPP---GPPGPP 1192 Score = 140 bits (352), Expect = 3e-32 Identities = 101/274 (36%), Positives = 117/274 (42%), Gaps = 44/274 (16%) Query: 2826 PGLPGPPG---PMGPPGDRGFTGKD--GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH 2880 PG P G P+ P G T ++ G GP+G GP G G G G G PG+PG Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141 Query: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM------LNQIPNDY 2934 G PGP G G G G+ A Q + + G M P + Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201 Query: 2935 QSSRNQPGPP---------GPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP---PGERGL 2982 Q +PG P GPPGPPG G GE G GRPG G PG QG PG GL Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261 Query: 2983 PGEKGERG----------TGSSGPRGLPGPPGPQG-ESRTGP---PGSTGSRGPPGPPGR 3028 PG KG RG G +GP+G PG PG G + GP PG G G PGP G Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321 Query: 3029 PGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 GN G G GPPG + P G+PG+ Sbjct: 322 RGNDGATGAAGPPG-------PTGPAGPPGFPGA 348 Score = 73.2 bits (178), Expect = 4e-12 Identities = 34/60 (56%), Positives = 35/60 (58%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 GP GP GP G GA G G G+ G IGPPGPRG G GP GPPGP GP G P G Sbjct: 1136 GPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 252 bits (643), Expect = 5e-66 Identities = 150/347 (43%), Positives = 169/347 (48%), Gaps = 66/347 (19%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG----LS 2800 + GPPGPPG AG PG +G GERG G+ GP G +G+ G PG G PG GP G + Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768 Query: 2801 IPGEQGRQGMKGDAGEPGLPGRTGTPGLP------GPPGPMGPPGDRGFTGKDGAMGPRG 2854 PG G+ G KG+ G PGLPG G G P GPPGP G PG G G+ G G RG Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828 Query: 2855 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914 PG G G PGV GP PG G G PGP G+KGE+G G + Sbjct: 829 APGEKGEGGPPGVAGP---PGGSGPAGPPGPQGVKGERGSPGGPGAAG------------ 873 Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGP------PGPPGPPGSAGARGEPGPGGRPGFP 2968 + +R PGP PGPPGP GS G G PGP G G P Sbjct: 874 -------------------FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914 Query: 2969 GTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGPPG 3024 G+PG+ GP G+ G PGEKG G+ GP G PGP G G GPPG G RG PG Sbjct: 915 GSPGVSGPKGDAGQPGEKG--SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG 972 Query: 3025 P---------PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 P PG G SG RGPPGP G + A P G PGS Sbjct: 973 PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP-GRDGNPGS 1018 Score = 250 bits (638), Expect = 2e-65 Identities = 147/330 (44%), Positives = 167/330 (50%), Gaps = 27/330 (8%) Query: 2724 PSRRDEGKCPAFPNSC--TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGD 2781 P + EG P P + G GPPGPAG PGA G GE G G G PG +G+ Sbjct: 776 PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE 835 Query: 2782 IGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDR 2841 GPPG GPPG GP G PG QG +G +G G PG G G GLPGPPG G PG Sbjct: 836 GGPPGVAGPPGGSGPAGP--PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893 Query: 2842 GFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH---------GRPGPSGLKGEK 2892 G +G G GP GP G G+PGSPGV+GP G G+PG+ G PGP G+ G Sbjct: 894 GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT 953 Query: 2893 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGS 2952 G RG +A M Q + G+ + N R GPPGP G PG Sbjct: 954 GARG-LAGPPGMPGPRGSPGPQGVKGESGKPG------ANGLSGER---GPPGPQGLPGL 1003 Query: 2953 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTG 3012 AG GEPG G PG G PG G PG +G GE G G+ G G PGPPGP G + G Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG--SPGAPGAPGHPGPPGPVGPA--G 1059 Query: 3013 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G G GP GP G PG +G RG PGP G Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQG 1089 Score = 247 bits (630), Expect = 1e-64 Identities = 145/329 (44%), Positives = 163/329 (49%), Gaps = 40/329 (12%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG------------PPGPRGDIGPPGPQGPPGPQ 2794 GPPG GPAG PG +G +GERG G G PPG G+ GPPGP G PG Sbjct: 843 GPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD 902 Query: 2795 GPNG----LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAM 2850 GP G PG G G KGDAG+PG G+PG GPPG GP G G TG G Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDAGQPG---EKGSPGAQGPPGAPGPLGIAGITGARGLA 959 Query: 2851 GPRGPPGPPGSPGSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907 GP G PGP GSPG GV G SGKPG G+ G PGP GL G G G+ + Sbjct: 960 GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019 Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967 + G+ +R P + PGPPGP GP G +G RGE GP G G Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPG----APGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075 Query: 2968 PGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE----SRTGP 3013 PG G +G PG +G G+KGE G G G G PG PGP G+ GP Sbjct: 1076 PGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP 1135 Query: 3014 PGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 G G GP GPPG+ G SG GP GPPG Sbjct: 1136 AGPRGPVGPSGPPGKDGTSGHPGPIGPPG 1164 Score = 245 bits (625), Expect = 6e-64 Identities = 158/366 (43%), Positives = 173/366 (47%), Gaps = 63/366 (17%) Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQ------------GPPGP 2793 +G PGP G G PG G RG G G GPPG G+ GP GP GPPGP Sbjct: 578 MGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637 Query: 2794 QGPNGL----SIPGEQGR---QGMKGDAGEPGLPGRTGTPGLP---GPPGPMGPPGDRGF 2843 QG GL PGE G+ G KGDAG PG PG G G P GPPG G PG RG Sbjct: 638 QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697 Query: 2844 TGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIASQ 2901 G G G +G GPPG PG+ G G G PG+ G G PGP G KGE G G + + Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757 Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961 + R + +GQ P D + PG PG GP GS G RGE GP Sbjct: 758 DGPRGPTGPIGPPGPAGQ-----------PGD-KGEGGAPGLPGIAGPRGSPGERGETGP 805 Query: 2962 GGRPGFPGTPGMQGPP---GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGESRT 3011 G GFPG PG G P GERG PGEKGE G G SGP G PGP G +GE + Sbjct: 806 PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGS 865 Query: 3012 ----------------GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYN 3055 GPPGS G+ GPPGP G PG G GP G G S S P Sbjct: 866 PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG-APGSPGVSGPKG 924 Query: 3056 GQGYPG 3061 G PG Sbjct: 925 DAGQPG 930 Score = 239 bits (611), Expect = 2e-62 Identities = 138/330 (41%), Positives = 160/330 (48%), Gaps = 20/330 (6%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IPGEQ 2805 GPPGP G G PG +G GE G +GA G PGPRG+ G G G PG +G +G PGE Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473 Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSP 2865 G G+ G AGE G PG G G G PG GP G+RG G G G G PG G PG P Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533 Query: 2866 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIA-----SQNMMRAVARQVCEQLISGQM 2920 G+ G G PG PG G+PGP G +GE G G Q + G+ Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593 Query: 2921 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 2980 P + GP GPPGP G G +G+ GP G G G PG GPPGE Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653 Query: 2981 GLPGEKGERGTGSSGPRGLPGPPGPQGES----RTGPPGSTGS---RGPPGPPGRPGNSG 3033 G PGE G +G G PG PG +G++ GPPG G+ RG GPPG G G Sbjct: 654 GKPGEPGPKGDA-----GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708 Query: 3034 IRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061 GPPGPPG + +P G G PG Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738 Score = 234 bits (596), Expect = 1e-60 Identities = 143/354 (40%), Positives = 166/354 (46%), Gaps = 37/354 (10%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-------L 2799 G PGP GP G PG +G G G +GA G G RG G PGP GPPG G G + Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRG------FTGKDGAMGPR 2853 G G G G GEPG G G G PGPPG G PG +G G G MG R Sbjct: 354 GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413 Query: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIASQNMMRAVARQV 2911 GPPGP G+ G+PG+ G +G+PGK G G PGP G +GE G G ++ + Sbjct: 414 GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473 Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP 2971 + G + P + GP G G PG AG RG G GR G PG P Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533 Query: 2972 GMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQG-------------ESRTGPPGST 3017 GM+G PG G PG G+ G GS G G PGPPGP G + G PG Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593 Query: 3018 GSR------GPPGPPGRPGNSGIRGPPGP--PGYCDSSQCASIPYNGQGYPGSG 3063 G R GP GPPG+ G +G +GPPGP PG P QG PG+G Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647 Score = 231 bits (589), Expect = 8e-60 Identities = 141/332 (42%), Positives = 161/332 (48%), Gaps = 28/332 (8%) Query: 2750 GPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQG 2809 GP GP G PG KGP GERG A GP GPRG G PG G PG G G+ PG G G Sbjct: 492 GPAGPNGIPGEKGPAGERG---APGPAGPRGAAGEPGRDGVPGGPGMRGM--PGSPGGPG 546 Query: 2810 MKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTG 2869 G G PG G +G PG PGP GP G PG GF G G G G G G PG PG G Sbjct: 547 SDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606 Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQML 2927 P GK G+ G G PGP+G G+KGD G Q + + E G+ Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666 Query: 2928 NQIPNDYQSSRNQPGPPGPP------------GPPGSAGARGEPGPGGRPGFPGTPGMQG 2975 + PG GPP GPPG G +G GP G PG GTPG+QG Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726 Query: 2976 PPGER---GLPGEKGERG-TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPG 3030 PGER G PG KG++G G G G+PG GP+G + GPPG G G G G PG Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786 Query: 3031 NSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 GI GP G PG + + P G+PG+ Sbjct: 787 LPGIAGPRGSPG----ERGETGPPGPAGFPGA 814 Score = 229 bits (584), Expect = 3e-59 Identities = 152/398 (38%), Positives = 167/398 (41%), Gaps = 81/398 (20%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGE---------RGISGAIGPPGPRGDIG 2783 PA PN + G G PGPAG GA G G RG+ G+ G PG G G Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPG 552 Query: 2784 PPGPQG------PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP--- 2834 PPG QG PPGP GP G PG G G KG+ G PG G G PG PGP GP Sbjct: 553 PPGSQGESGRPGPPGPSGPRGQ--PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610 Query: 2835 ---MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891 GP G G TG G G GPPGP G G PG GP G+ GKPG+ G G +G G Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670 Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP-- 2949 G +GD + L G P + + GPPGPPG Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAG----------PPGPEGGKGAAGPPGPPGAAG 720 Query: 2950 -------PGSAGARGEPGPGGRPGFPGTPGMQ---------------GPPGERGLPGEKG 2987 PG G G PGP G G PG PG GPPG G PG+KG Sbjct: 721 TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG 780 Query: 2988 ERG-------------------TGSSGPRGLPGPPG----PQGESRTGPPGSTGSRGPPG 3024 E G TG GP G PG PG P G+ G PG G GPPG Sbjct: 781 EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840 Query: 3025 PPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062 G PG SG GPPGP G P G+PG+ Sbjct: 841 VAGPPGGSGPAGPPGPQGVKGERGSPGGP-GAAGFPGA 877 Score = 229 bits (583), Expect = 4e-59 Identities = 143/353 (40%), Positives = 167/353 (47%), Gaps = 47/353 (13%) Query: 2732 CPAFPNSCTCTQDSVGPPGP---PGPAGGPGAKGPRGERGISGAIGPPGPRG-------- 2780 CP P + T + GP GP PGP G PG G G G G+ G PGP G Sbjct: 88 CPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG 147 Query: 2781 -----------DI----------GPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGL 2819 D+ G PGP GPPGP GP G S G G G G G PG Sbjct: 148 PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS--GHPGSPGSPGYQGPPGE 205 Query: 2820 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD 2879 PG+ G G PGPPG +GP G GKDG G G PG G PG PG+ GP+G PG PG Sbjct: 206 PGQAGPSGPPGPPGAIGPSGP---AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGM 262 Query: 2880 HGRPGPSGLKGEKGDRG--DIASQNMM---RAVARQVCEQLISGQMNRFNQMLNQIPNDY 2934 G G G GEKG+ G + +N + + + G+ R Sbjct: 263 KGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322 Query: 2935 QSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GS 2993 +R G PGPPGPPG+AG G PG G G G+PG G PG+RG PG +G G G Sbjct: 323 DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382 Query: 2994 SGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042 GP G+ G PG +GE G PG G+RGPPGP G G G+RG G PG Sbjct: 383 PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435 Score = 211 bits (536), Expect = 1e-53 Identities = 123/292 (42%), Positives = 139/292 (47%), Gaps = 65/292 (22%) Query: 2747 GPPGPPGPAGGPGAKGPRGE------RGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNGL 2799 GPPG PGP G PG +G +GE G+SG GPPGP+G G G G PG G P Sbjct: 960 GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019 Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859 +PG G G KGD GE G PG G PG PGPPGP+GP G G G+ G GP G PGP Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPA 1079 Query: 2860 GSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQ 2919 GS G+PG GP G G+ G+ G +G+KG +G G+ Sbjct: 1080 GSRGAPGPQGPRGDKGETGER---GAAGIKGHRGFPGN---------------------- 1114 Query: 2920 MNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE 2979 PG PG PGP G GA G PGP G G G GPPG+ Sbjct: 1115 ---------------------PGAPGSPGPAGQQGAIGSPGPAGP---RGPVGPSGPPGK 1150 Query: 2980 RGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPG 3030 G G GP G PGP G +GE G PG G GPPGPPG PG Sbjct: 1151 DGTSGH--------PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194 Score = 205 bits (521), Expect = 6e-52 Identities = 138/371 (37%), Positives = 163/371 (43%), Gaps = 60/371 (16%) Query: 2720 CCDIPSRRDEGKCP----AFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP 2775 C DI E CP F C +V P P P P +GP+G +G G G Sbjct: 62 CDDIICDDQELDCPNPEIPFGECC-----AVCPQPPTAPTRPPNGQGPQGPKGDPGPPGI 116 Query: 2776 PGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835 PG GD G PG G PG GP G+ G Q + GL G PGP Sbjct: 117 PGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPA 176 Query: 2836 GP---------------PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGP------SGKP 2874 GP PG G+ G G G GP GPPG PG+ G +GP SG+P Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236 Query: 2875 GKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY 2934 G+PG+ G PGP G+KG G G R + E+ +G + N +P + Sbjct: 237 GRPGERGLPGPPGIKGPAGIPG-FPGMKGHRGFDGRNGEKGETGAPGLKGE--NGLPGEN 293 Query: 2935 -----QSSRNQPGPPGPPGPPGSAGARGE------------PGPGGRPGFPGTPGMQ--- 2974 R PG G PG PG+AGARG PGP G GFPG+PG + Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353 Query: 2975 ---GPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGN 3031 G PG G PG++GE G G G GPPGP G + G PG G GP G PG PG Sbjct: 354 GPAGSPGSNGAPGQRGE--PGPQGHAGAQGPPGPPGIN--GSPGGKGEMGPAGIPGAPGL 409 Query: 3032 SGIRGPPGPPG 3042 G RGPPGP G Sbjct: 410 MGARGPPGPAG 420 Score = 148 bits (373), Expect = 9e-35 Identities = 78/156 (50%), Positives = 84/156 (53%), Gaps = 10/156 (6%) Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPG 2803 S G PG PG G PG GP G+ G G GP GP G GP G +G PGPQGP G G Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETG 1098 Query: 2804 EQGRQGMKGDAGEPGLPGRTGTP---------GLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854 E+G G+KG G PG PG G+P G PGP GP GP G G GKDG G G Sbjct: 1099 ERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPG 1158 Query: 2855 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890 P GPPG G+ G G G PG PG G PGP G G Sbjct: 1159 PIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194 Score = 141 bits (356), Expect = 9e-33 Identities = 93/239 (38%), Positives = 108/239 (45%), Gaps = 54/239 (22%) Query: 2813 DAGEPGLPGRTGTPGLPGPP-GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPS 2871 D P +P P PP P PP +G P+GP G PG PG PG G Sbjct: 73 DCPNPEIPFGECCAVCPQPPTAPTRPPNGQG---------PQGPKGDPGPPGIPGRNGDP 123 Query: 2872 GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931 G PG+PG G PGP G +CE +G N Q + Sbjct: 124 GIPGQPGSPGSPGPPG-----------------------ICESCPTGPQNYSPQYDSY-- 158 Query: 2932 NDYQSS------RNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 2985 D +S PGP GPPGPPG PG G PG PG+PG QGPPGE PG+ Sbjct: 159 -DVKSGVAVGGLAGYPGPAGPPGPPGP------PGTSGHPGSPGSPGYQGPPGE---PGQ 208 Query: 2986 KGERGTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043 G +G GP G GP GP G + +G PG G RG PGPPG G +GI G PG G+ Sbjct: 209 AGP--SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH 265 Score = 139 bits (349), Expect = 6e-32 Identities = 77/171 (45%), Positives = 87/171 (50%), Gaps = 30/171 (17%) Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806 G PGPPGP G G G RGE G +G G PGP G G PGPQGP G +G G E+G Sbjct: 1047 GHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETG-----ERG 1101 Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPG---------------PPGPMGPPGDRGFTGKDGAMG 2851 G+KG G PG PG G+PG G P GP GPPG G +G G +G Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIG 1161 Query: 2852 PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP----------SGLKGEK 2892 P GP G G GS G G G+PG PG G PGP +G+ GEK Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212 Score = 96.7 bits (239), Expect = 3e-19 Identities = 56/128 (43%), Positives = 59/128 (46%), Gaps = 23/128 (17%) Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISG--------------------- 2771 PA P S G PGP GP G G G RG GI G Sbjct: 1069 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG 1128 Query: 2772 AIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 2831 AIG PGP G GP GP GPPG G +G PG G G +G+ GE G G G PG PGP Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPGKDGTSG--HPGPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186 Query: 2832 PGPMGPPG 2839 PGP G PG Sbjct: 1187 PGPPGAPG 1194 Score = 87.4 bits (215), Expect = 2e-16 Identities = 50/126 (39%), Positives = 60/126 (47%), Gaps = 17/126 (13%) Query: 2931 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG-----PPGERGLPGE 2985 P + + GP G PGPPG G G+PG G+PG PG+PG G P G + + Sbjct: 95 PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ 154 Query: 2986 KG----ERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041 + G G G PGP GP G PPG G+ G PG PG PG +GPPG P Sbjct: 155 YDSYDVKSGVAVGGLAGYPGPAGPPG-----PPGPPGTSGHPGSPGSPG---YQGPPGEP 206 Query: 3042 GYCDSS 3047 G S Sbjct: 207 GQAGPS 212 Score = 56.6 bits (135), Expect = 4e-07 Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 7/65 (10%) Query: 2991 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 3050 T + P GP GP+G+ GPPG G G PG PG+PG+ G PGPPG C+S C Sbjct: 93 TAPTRPPNGQGPQGPKGDP--GPPGIPGRNGDPGIPGQPGSPG---SPGPPGICES--CP 145 Query: 3051 SIPYN 3055 + P N Sbjct: 146 TGPQN 150 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.133 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 142,390,407 Number of Sequences: 37866 Number of extensions: 8746169 Number of successful extensions: 182842 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 506 Number of HSP's successfully gapped in prelim test: 1442 Number of HSP's that attempted gapping in prelim test: 34011 Number of HSP's gapped (non-prelim): 29108 length of query: 3063 length of database: 18,247,518 effective HSP length: 121 effective length of query: 2942 effective length of database: 13,665,732 effective search space: 40204583544 effective search space used: 40204583544 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.