Guide to the Human Genome
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Search of human proteins with 93141047

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
         (3063 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...  6192   0.0  
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...  3858   0.0  
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]               1267   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               439   e-122
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                427   e-119
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]      387   e-107
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]      386   e-106
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]      383   e-105
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]      383   e-105
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]      382   e-105
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         352   4e-96
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]      342   3e-93
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]      342   4e-93
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   333   2e-90
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]        278   8e-74
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     264   9e-70
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       259   2e-68
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      259   3e-68
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   254   7e-67
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   254   7e-67
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   254   7e-67
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          254   9e-67
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   253   2e-66
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   253   2e-66
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   253   2e-66
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   253   2e-66
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   253   2e-66
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...   253   2e-66
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     252   3e-66
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     252   5e-66

>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score = 6192 bits (16065), Expect = 0.0
 Identities = 3063/3063 (100%), Positives = 3063/3063 (100%)

Query: 1    MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVD 60
            MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVD
Sbjct: 1    MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVD 60

Query: 61   PTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKP 120
            PTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKP
Sbjct: 61   PTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKP 120

Query: 121  VEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG 180
            VEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG
Sbjct: 121  VEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVG 180

Query: 181  VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVG 240
            VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVG
Sbjct: 181  VVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVG 240

Query: 241  FPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVA 300
            FPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVA
Sbjct: 241  FPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVA 300

Query: 301  NFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP 360
            NFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP
Sbjct: 301  NFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSP 360

Query: 361  VTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIME 420
            VTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIME
Sbjct: 361  VTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIME 420

Query: 421  KTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQIS 480
            KTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQIS
Sbjct: 421  KTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQIS 480

Query: 481  LVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN 540
            LVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN
Sbjct: 481  LVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN 540

Query: 541  VPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVE 600
            VPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVE
Sbjct: 541  VPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVE 600

Query: 601  DFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVF 660
            DFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVF
Sbjct: 601  DFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVF 660

Query: 661  SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE 720
            SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE
Sbjct: 661  SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE 720

Query: 721  EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLE 780
            EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLE
Sbjct: 721  EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLE 780

Query: 781  NLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGK 840
            NLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGK
Sbjct: 781  NLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGK 840

Query: 841  VKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGT 900
            VKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGT
Sbjct: 841  VKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGT 900

Query: 901  TLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT 960
            TLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT
Sbjct: 901  TLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT 960

Query: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020
            MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP
Sbjct: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020

Query: 1021 GKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080
            GKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS
Sbjct: 1021 GKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080

Query: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140
            GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN
Sbjct: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140

Query: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADI 1200
            TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADI
Sbjct: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADI 1200

Query: 1201 VLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKK 1260
            VLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKK
Sbjct: 1201 VLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKK 1260

Query: 1261 SLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320
            SLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS
Sbjct: 1261 SLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320

Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380
            KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK
Sbjct: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380

Query: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTV 1440
            GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTV
Sbjct: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTV 1440

Query: 1441 LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA 1500
            LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA
Sbjct: 1441 LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA 1500

Query: 1501 TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR 1560
            TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR
Sbjct: 1501 TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR 1560

Query: 1561 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS 1620
            EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS
Sbjct: 1561 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS 1620

Query: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680
            LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS
Sbjct: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680

Query: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
            DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS
Sbjct: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740

Query: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800
            ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT
Sbjct: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800

Query: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 1860
            IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL
Sbjct: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 1860

Query: 1861 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 1920
            NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG
Sbjct: 1861 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 1920

Query: 1921 DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI 1980
            DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI
Sbjct: 1921 DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI 1980

Query: 1981 VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS 2040
            VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS
Sbjct: 1981 VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS 2040

Query: 2041 LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE 2100
            LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE
Sbjct: 2041 LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE 2100

Query: 2101 DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME 2160
            DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME
Sbjct: 2101 DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME 2160

Query: 2161 AFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220
            AFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF
Sbjct: 2161 AFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220

Query: 2221 CVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280
            CVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE
Sbjct: 2221 CVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280

Query: 2281 GPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFN 2340
            GPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFN
Sbjct: 2281 GPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFN 2340

Query: 2341 KVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGN 2400
            KVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGN
Sbjct: 2341 KVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGN 2400

Query: 2401 TRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGV 2460
            TRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGV
Sbjct: 2401 TRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGV 2460

Query: 2461 ADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPG 2520
            ADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPG
Sbjct: 2461 ADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPG 2520

Query: 2521 FKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTII 2580
            FKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTII
Sbjct: 2521 FKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTII 2580

Query: 2581 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV 2640
            LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV
Sbjct: 2581 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV 2640

Query: 2641 KTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAA 2700
            KTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAA
Sbjct: 2641 KTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAA 2700

Query: 2701 FQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGA 2760
            FQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGA
Sbjct: 2701 FQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGA 2760

Query: 2761 KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLP 2820
            KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLP
Sbjct: 2761 KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLP 2820

Query: 2821 GRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH 2880
            GRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH
Sbjct: 2821 GRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH 2880

Query: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ 2940
            GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ
Sbjct: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ 2940

Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000
            PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP
Sbjct: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000

Query: 3001 GPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP 3060
            GPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP
Sbjct: 3001 GPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP 3060

Query: 3061 GSG 3063
            GSG
Sbjct: 3061 GSG 3063


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score = 3858 bits (10006), Expect = 0.0
 Identities = 1876/1879 (99%), Positives = 1877/1879 (99%)

Query: 1185 ILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS 1244
            I + GMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS
Sbjct: 21   IEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYS 80

Query: 1245 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304
            GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG
Sbjct: 81   GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 140

Query: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364
            VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL
Sbjct: 141  VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 200

Query: 1365 SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG 1424
            SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG
Sbjct: 201  SRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSG 260

Query: 1425 GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD 1484
            GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD
Sbjct: 261  GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYD 320

Query: 1485 VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 1544
            VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT
Sbjct: 321  VGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 380

Query: 1545 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 1604
            VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE
Sbjct: 381  VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 440

Query: 1605 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT 1664
            EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT
Sbjct: 441  EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKIT 500

Query: 1665 EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI 1724
            EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI
Sbjct: 501  EVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSI 560

Query: 1725 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 1784
            TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR
Sbjct: 561  TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 620

Query: 1785 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844
            ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL
Sbjct: 621  ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680

Query: 1845 NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 1904
            NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ
Sbjct: 681  NTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQ 740

Query: 1905 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY 1964
            PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY
Sbjct: 741  PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQY 800

Query: 1965 RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP 2024
            RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP
Sbjct: 801  RVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLP 860

Query: 2025 RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP 2084
            RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP
Sbjct: 861  RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQP 920

Query: 2085 LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144
            LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL
Sbjct: 921  LQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVL 980

Query: 2145 GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY 2204
            GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY
Sbjct: 981  GYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLY 1040

Query: 2205 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP 2264
            LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP
Sbjct: 1041 LNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSP 1100

Query: 2265 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI 2324
            DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI
Sbjct: 1101 DTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADI 1160

Query: 2325 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK 2384
            VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK
Sbjct: 1161 VFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDK 1220

Query: 2385 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA 2444
            ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA
Sbjct: 1221 ALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKA 1280

Query: 2445 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA 2504
            ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA
Sbjct: 1281 ALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETA 1340

Query: 2505 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP 2564
            TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP
Sbjct: 1341 TSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQP 1400

Query: 2565 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK 2624
            TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK
Sbjct: 1401 TADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNK 1460

Query: 2625 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG 2684
            DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG
Sbjct: 1461 DTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDG 1520

Query: 2685 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD 2744
            YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD
Sbjct: 1521 YEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQD 1580

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE
Sbjct: 1581 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 1640

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
            QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS
Sbjct: 1641 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 1700

Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924
            PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN
Sbjct: 1701 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 1760

Query: 2925 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG 2984
            QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG
Sbjct: 1761 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPG 1820

Query: 2985 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC 3044
            EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC
Sbjct: 1821 EKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYC 1880

Query: 3045 DSSQCASIPYNGQGYPGSG 3063
            DSSQCASIPYNGQGYPGSG
Sbjct: 1881 DSSQCASIPYNGQGYPGSG 1899



 Score =  490 bits (1262), Expect = e-138
 Identities = 336/1084 (30%), Positives = 527/1084 (48%), Gaps = 70/1084 (6%)

Query: 127  KTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSS 186
            + E  +C   A  D+V LVDGSWS+GR NF+ +  FI+ +V  FDIG ++ ++ + QYS 
Sbjct: 22   EAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSG 81

Query: 187  DTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAI 246
            D RTE+ LN +  +  LL A+  +PYKGGNT+TG A++++ +  F   AG R    K+ +
Sbjct: 82   DPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGV 141

Query: 247  IITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIV 306
            +ITDGKSQD+VE P+++L++ GVE+F++GIK AD  ELK IA+ P   H +NVA+F+++ 
Sbjct: 142  LITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLS 201

Query: 307  DIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKV 366
             I +++   +C+         V G   +E PSNL+  E + +  +++W P    V  YKV
Sbjct: 202  RIVDDLTINLCNS--------VKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKV 253

Query: 367  ILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMK 426
               P++ G RQ       +T+T+ ++DL  +TEY ++V ++     SEP+   EKT P+ 
Sbjct: 254  EYYPVSGGKRQEFYVSRMETSTV-LKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP 312

Query: 427  -VQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYS 485
             V +           + +   G  +  I ++  V+       K   + P    + L    
Sbjct: 313  VVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLV 372

Query: 486  RDPHTEFTLKKFTKVEDII-EAIN----TFPYRGGSTNTGKAMTYVREKIF---VPSKGS 537
              P+TE+ +     + D+  E +     T P         + +T+    +F   VP K  
Sbjct: 373  --PNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGK-V 429

Query: 538  RSNVPKVMILITDGKSSDAFR-DPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHV 596
            R  + +      D K  +  R + +  L++   +        AV  E E   SPP     
Sbjct: 430  RKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE---SPPVTAQ- 485

Query: 597  FTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAG 656
                          E T+ +      ++  +  + +    D   S+V+ Y  +  W+P G
Sbjct: 486  --------------ETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLY--RITWAPFG 529

Query: 657  ENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYED-GFSIPLAG 715
             +              D++  +      ++V  +L P T+Y V++TA Y D   S  L G
Sbjct: 530  SS--------------DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 575

Query: 716  EE------TTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAG-GESREV 768
             E      TT+  K  PRNL+V + T++S  + W  A GRV +YRI Y+P  G G  +  
Sbjct: 576  SERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 635

Query: 769  TTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTS 828
            T    Q    L+ L PDT Y ++V   Y  G G  +TG   T+ +    R+LRV DP+TS
Sbjct: 636  TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL-NTVRNLRVYDPSTS 694

Query: 829  TMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYA 888
            T+ + W  A G  +QY + Y P AGG  + V + G+T   +L+ L+  T Y ++V  +Y 
Sbjct: 695  TLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 754

Query: 889  SGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDT 948
             G G      G TL  RG  +++   + T  S+   W  APG V  YRV +  +     +
Sbjct: 755  EGDGGRTSDTGRTL-MRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 813

Query: 949  GEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEET 1008
                +P +     +E L P+T Y +++ A YS GEG P      T      + L+V  ET
Sbjct: 814  ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 873

Query: 1009 ENTMRVTWKPAPGKVVNYRVVYRPH-GRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLP 1067
             N++ V W  A G V  YR++Y P  G        VP    + +L+ LQP T Y ITV+ 
Sbjct: 874  TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 933

Query: 1068 IYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDD 1127
            +Y+ G+G    G+G T      P+N+  SD   + FRV+W+P+P  V GYK+ + P G +
Sbjct: 934  VYEDGDGGHLTGNGRTVG-LLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSN 992

Query: 1128 RRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILS 1187
              + E  VG    +  L  L   TTY VNV+  +D G S PL  Q  T   + T +    
Sbjct: 993  EPM-EAFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQ 1050

Query: 1188 SGME 1191
             G +
Sbjct: 1051 IGWD 1054



 Score =  426 bits (1094), Expect = e-118
 Identities = 326/1094 (29%), Positives = 512/1094 (46%), Gaps = 61/1094 (5%)

Query: 309  QNEIISQVCSGVDEQLGELVSGEE--VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKV 366
            + E +  V S V+++  E + G E  +  P  +L   +V    + + W P     TGY +
Sbjct: 283  ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYIL 341

Query: 367  ILTPM--TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424
               P+  T  +R   + +GP    + + DL  +TEY ++V A+    +SEP+++ E T P
Sbjct: 342  SYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLP 401

Query: 425  MKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQY 484
            +       R  D+K     L D ++S        +  F E +       P +V+  +V+Y
Sbjct: 402  LP------RPQDLK-----LRDVTHST-------MNVFWEPV-------PGKVRKYIVRY 436

Query: 485  SRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKV 544
             + P  +    +  + E      + F     + +   A+    E   V ++ +   VP  
Sbjct: 437  -KTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVS-AVHDEGESPPVTAQETTRPVPAP 494

Query: 545  MILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSE-LEAIASPPAETHVFTVEDFD 603
              L     +S+ FR        SDV ++ +       S+ +E I +    T VF   + +
Sbjct: 495  TNLKITEVTSEGFRG-TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPN 553

Query: 604  AFQRISF------ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAG 656
                +S       E      +  E+ L  +  +A    P++L     TS      W PA 
Sbjct: 554  TIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPAS 613

Query: 657  ENVFSYHITYKEAAGD-DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAG 715
              V  Y ITY+ + G+ +E T        SVVL  LKP+T Y + V++ Y DG    + G
Sbjct: 614  GRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTG 673

Query: 716  EETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR 775
               T+ +    RNL+V D +T +  + W  A G   +Y++ Y P AGG    V  P N  
Sbjct: 674  RGKTKPLNTV-RNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTN 732

Query: 776  RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWS 835
               L NL PDT Y V+V+P Y  G G   T +     +RG  R+++V +PT +++ + W 
Sbjct: 733  YAILRNLQPDTSYTVTVVPVYTEGDGGR-TSDTGRTLMRGLARNVQVYNPTPNSLDVRWD 791

Query: 836  GAPGKVKQYLVTYTPVAGGETQE-VTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDA 894
             APG V QY V Y+PV G    E + V G+T    L+ L   T Y++++ ALY+ G G+ 
Sbjct: 792  PAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNP 851

Query: 895  LFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLP 954
               +G TL   G P++L     T  S+   W  A G V+ YR+ +     D       +P
Sbjct: 852  SPAQGRTLPRSG-PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP 910

Query: 955  EDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRV 1014
                + +++ LQP+T Y+I+V A Y  G+G  LTG+  T      + + + +E     RV
Sbjct: 911  GRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRV 970

Query: 1015 TWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEG 1074
            +W P+P  V+ Y++VY+P G  + M A V   +TS  L  L P TTYD+ V   Y  G  
Sbjct: 971  SWDPSPSPVLGYKIVYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLS 1029

Query: 1075 KLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELV 1134
                  GTT   + +  +LKT      +F V W P       Y++   P  D  R  E+ 
Sbjct: 1030 VPLTDQGTTL--YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSP-ADGTRGQEIT 1085

Query: 1135 VGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTV---------MPI 1185
            V   + +     L   T Y V VF      E   +  +E TT+  T            P 
Sbjct: 1086 VRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPT 1145

Query: 1186 LSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFD-IGPKRVQIALAQYS 1244
            +    +    A+ADIV L D SWSIG  NF  V  FI   V  FD I P  +Q++  QYS
Sbjct: 1146 IPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYS 1205

Query: 1245 GDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIG 1304
             + ++E++LN + DK   L A+ N+ Y+GGNT TG AL FI+++    ++GMR    K+ 
Sbjct: 1206 DEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVL 1265

Query: 1305 VLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESL 1364
            V++TDG+SQD+V+  +  ++  G  +F +G+ + D  EL  IA+ P + H + V DFES 
Sbjct: 1266 VVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESF 1325

Query: 1365 SRIVDDLTINLCNS 1378
             +I D+L   +C +
Sbjct: 1326 EKIEDNLITFVCET 1339



 Score =  171 bits (434), Expect = 8e-42
 Identities = 122/370 (32%), Positives = 182/370 (49%), Gaps = 28/370 (7%)

Query: 352  LNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMT 411
            + W+P  +  T Y++ L+P   G+R   ++V    T+     LS DT+Y ++V       
Sbjct: 1058 VKWSPHRA-ATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNL 1115

Query: 412  SSEPISIMEKTQ-------------PMKVQVECSRGV--DIKADIVFLVDGSYSIGIANF 456
                +S+ E T              P    +  +R V    KADIVFL D S+SIG  NF
Sbjct: 1116 EGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNF 1175

Query: 457  VKVRAFLEVLVKSF-EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGG 515
             KV  F+   V  F EISP  +Q+S VQYS +  +EF L  +      + A+    YRGG
Sbjct: 1176 NKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGG 1235

Query: 516  STNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVG 575
            +T TGKA+T+++EK+     G R NVPKV++++TDG+S D  +  A+ ++ S   +F VG
Sbjct: 1236 NTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVG 1295

Query: 576  VKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPP 635
            V D   +EL  IAS P+E HVF V+DF++F++I   L   +C         I    Y  P
Sbjct: 1296 VADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSP 1355

Query: 636  --KDLSFSEVTSYGFKTNWSPAGEN----VFSYHITYKEAAGDDEVTVVE----PASSTS 685
              K L    +T   F +    + E+     +S +   K A  +     +     P S T 
Sbjct: 1356 GFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTI 1415

Query: 686  VVLSSLKPET 695
            ++L  L PET
Sbjct: 1416 ILLFRLLPET 1425



 Score =  162 bits (411), Expect = 4e-39
 Identities = 103/295 (34%), Positives = 154/295 (52%), Gaps = 7/295 (2%)

Query: 29   SDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPET 88
            +DL    I  +T  + W+ P      YR+ + P      +E T+  S T    + L P+T
Sbjct: 1044 TDLKTYQIGWDTFCVKWS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDT 1102

Query: 89   EYVVTITSYDEVEES--VPVIGQLTIQ-TGSSTKPVEKKPGKT--EIQKCSVSAWTDLVF 143
            +Y VT+       E   V V    T++ T + T+P    P  T    +     A  D+VF
Sbjct: 1103 DYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVF 1162

Query: 144  LVDGSWSVGRNNFKYILDFIAALVSAFD-IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDE 202
            L D SWS+G +NF  ++ FI   V  FD I     +V  VQYS + ++EF LN Y  +  
Sbjct: 1163 LTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKAL 1222

Query: 203  LLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPAR 262
             L A++ I Y+GGNT TG A+ ++ +   T  +G R   PKV +++TDG+SQDEV+  A 
Sbjct: 1223 ALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAAL 1282

Query: 263  ELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVC 317
             ++  G  VF +G+   D  EL  IAS PS  HVF V +F++   I++ +I+ VC
Sbjct: 1283 VIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVC 1337



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 30/85 (35%), Positives = 46/85 (54%)

Query: 24  EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
           +++ PS+L        +  +SW  P D +  Y++   P + G  +EF +S   T T+L +
Sbjct: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279

Query: 84  LVPETEYVVTITSYDEVEESVPVIG 108
           L PETEYVV + S  E E S P+ G
Sbjct: 280 LKPETEYVVNVYSVVEDEYSEPLKG 304



 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 24/24 (100%), Positives = 24/24 (100%)

Query: 1  MRSRLPPALAALGAALLLSSIEAE 24
          MRSRLPPALAALGAALLLSSIEAE
Sbjct: 1  MRSRLPPALAALGAALLLSSIEAE 24



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 27  PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDG-PT--KEFTLSASTTETLLSE 83
           P   LN   +   T+H+ W +PV    GY ++  P  D  PT  KE  L  +  +  L++
Sbjct: 312 PVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTD 370

Query: 84  LVPETEYVVTITS--YDEVEESVPV 106
           LVP TEY VT+ +  +D   E V V
Sbjct: 371 LVPNTEYAVTVQAVLHDLTSEPVTV 395



 Score = 37.7 bits (86), Expect = 0.18
 Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 1/82 (1%)

Query: 16  LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
           L + + +A    P +L       N++ + W      +  YRIT  P+T +G  +  T+  
Sbjct: 580 LPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGG 639

Query: 75  STTETLLSELVPETEYVVTITS 96
                +L +L P+T Y +T++S
Sbjct: 640 RQNSVVLQKLKPDTPYTITVSS 661



 Score = 37.4 bits (85), Expect = 0.23
 Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 32  NFKIIDE--NTVHMSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPET 88
           N ++  E  N++ ++W     P+  YRI   PT   P  E+ T+       +L  L P+T
Sbjct: 866 NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 925

Query: 89  EYVVTITSYDE 99
            Y +T+ +  E
Sbjct: 926 PYKITVIAVYE 936



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 1/85 (1%)

Query: 27   PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVP 86
            PP +++          +SW     P++GY+I   P       E  +   T+ T L  L P
Sbjct: 954  PPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYT-LHNLNP 1012

Query: 87   ETEYVVTITSYDEVEESVPVIGQLT 111
             T Y V + +  +   SVP+  Q T
Sbjct: 1013 STTYDVNVYAQYDSGLSVPLTDQGT 1037



 Score = 32.3 bits (72), Expect = 7.4
 Identities = 26/116 (22%), Positives = 45/116 (38%), Gaps = 1/116 (0%)

Query: 25  VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSEL 84
           V  P++L    +       +W      +  YRIT  P       E  L+      +   L
Sbjct: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 550

Query: 85  VPETEYVVTITS-YDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
            P T Y V+IT+ Y +  ES  +IG        +T+  +  P   ++   + ++ T
Sbjct: 551 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLT 606


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score = 1267 bits (3278), Expect = 0.0
 Identities = 653/1459 (44%), Positives = 899/1459 (61%), Gaps = 54/1459 (3%)

Query: 1627 QTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYR 1686
            ++L     S V ++      +A   T P   PT L  +EVT+  F   W H   +V  YR
Sbjct: 328  ESLTRTLCSRVEEQDREIKASAHAITGP---PTELITSEVTARSFMVNWTHAPGNVEKYR 384

Query: 1687 ITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPI 1746
            + + P       E +++G  ++ V +NL   T Y++++ AIY   + S+ L G+E TL +
Sbjct: 385  VVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYA-HTASEGLRGTETTLAL 443

Query: 1747 LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTG--EGNEQTTTIGGR 1804
                       +L +Y+ T NS+ VKWD   G    Y I Y P T    G+E+   IG  
Sbjct: 444  PMAS-------DLLLYDVTENSMRVKWDAVPG-ASGYLILYAPLTEGLAGDEKEMKIGET 495

Query: 1805 QNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRW 1864
               + L  L P+T YT+TV +++ +     +TG+  T  L+  RNLR+ +  +++  + W
Sbjct: 496  HTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTW 555

Query: 1865 DHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGR 1924
            D        Y++ Y  A G     V +   T +  L+ L P T YT+ +  +Y EG    
Sbjct: 556  DPTSRQINGYRIVYNNADGTEINEVEVDPITTFP-LKGLTPLTEYTIAIFSIYDEGQSEP 614

Query: 1925 TSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPG 1984
             +    T      + +++   T +S  V W P       +++++ PV G +  E ++   
Sbjct: 615  LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674

Query: 1985 NTRMVHLERLIPDTLYSVNLVALYSDG-EGNPSPAQGRTLP------------------- 2024
                V +E L P T Y V+L+A+  DG E     A G TL                    
Sbjct: 675  QDSHV-IEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSV 733

Query: 2025 -RSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEY---TTVPGRRNNV 2080
             ++G RNL V  ETT+SL V WD +D  VQQ+R+ Y    GDP +E      VPG +NN+
Sbjct: 734  FQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNL 793

Query: 2081 ILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSP 2140
            +L+PL PDT YK+TV  +Y DG+G  ++  G+T+    PQN+ +S+EWY R R++WDP  
Sbjct: 794  LLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853

Query: 2141 SPVLGYKIVYKPVGSNEP-MEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTD 2198
            SPV GY+IVYKPV    P +E FVG ++ +  + NL     Y+V ++A   SG S  LT 
Sbjct: 854  SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913

Query: 2199 QGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHC 2258
               TL+L VT+L+   +   + C  W  HR AT+YR+ +      + QE TV G  T HC
Sbjct: 914  MVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHC 973

Query: 2259 FTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCK 2318
            F GL PD++Y ++V+ +   +EGP VS+ E T   PT  PT PPT      IPPA++VCK
Sbjct: 974  FYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPT------IPPAKEVCK 1027

Query: 2319 GAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKL 2378
             AKAD+VF+ D SWSIGD+NFNK++ F+++TVG  ++I   G QV+ VQ++D+ ++EFKL
Sbjct: 1028 AAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKL 1087

Query: 2379 NTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQ 2438
            N Y  K   L A+++I Y+GGNT+TGKA+ ++++ + T ESG R+ +PKV+VV+TDGRSQ
Sbjct: 1088 NAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQ 1147

Query: 2439 DEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLIT 2498
            D+V K +  +Q  G+S+F +GVAD DY+EL +I SKPS RHVF VDDF++F+KIED LIT
Sbjct: 1148 DDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELIT 1207

Query: 2499 FVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKN 2558
            FVCETA+++CP+++ DG    GFKM+E + L EK+F+SV+GVS+E G+F  +  Y++ K+
Sbjct: 1208 FVCETASATCPVVHKDGIDLAGFKMMEMFGLVEKDFSSVEGVSMEPGTFNVFPCYQLHKD 1267

Query: 2559 AFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKT 2618
            A V+QPT  LHP GLP  YTI  LFR+LP+TP +PFA+W+I +++  P VGVI D   KT
Sbjct: 1268 ALVSQPTRYLHPEGLPSDYTISFLFRILPDTPQEPFALWEILNKNSDPLVGVILDNGGKT 1327

Query: 2619 LSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAG 2678
            L++FN D  G+ QTVTF+  E++ +FYGSFHK+HIVV+   VK+ IDC ++ EK +  + 
Sbjct: 1328 LTYFNYDQSGDFQTVTFEGPEIRKIFYGSFHKLHIVVSETLVKVVIDCKQVGEKAMNASA 1387

Query: 2679 NITTDGYEILGKLLKGE---RKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAF 2735
            NIT+DG E+LGK+++       SA FQ+Q FDIVCS  W + D+CC++P  RD+  CP  
Sbjct: 1388 NITSDGVEVLGKMVRSRGPGGNSAPFQLQMFDIVCSTSWANTDKCCELPGLRDDESCPDL 1447

Query: 2736 PNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 2795
            P+SC+C++ +    GP GP GGPG +GP+G++G  G  GP GPRG+IG PGPQGPPGPQG
Sbjct: 1448 PHSCSCSETNEVALGPAGPPGGPGLRGPKGQQGEPGPKGPDGPRGEIGLPGPQGPPGPQG 1507

Query: 2796 PNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP 2855
            P+GLSI G  G  G KG+ G+ GLPG  G PG  G PG  G PG RG  GKDG+ GP GP
Sbjct: 1508 PSGLSIQGMPGMPGEKGEKGDTGLPGPQGIPGGVGSPGRDGSPGQRGLPGKDGSSGPPGP 1567

Query: 2856 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915
            PGP G PG+PGV G +G  G  G  G PG  G KGE+G+RGD+ SQ M+R+VARQVCEQL
Sbjct: 1568 PGPIGIPGTPGVPGITGSMGPQGALGPPGVPGAKGERGERGDLQSQAMVRSVARQVCEQL 1627

Query: 2916 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG 2975
            I   M R+  +LNQIP+   S R   GPPG PG PGS GA GE GP G PGFPG  G+ G
Sbjct: 1628 IQSHMARYTAILNQIPSHSSSIRTVQGPPGEPGRPGSPGAPGEQGPPGTPGFPGNAGVPG 1687

Query: 2976 PPGERGLPGEKGER---GTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNS 3032
             PGERGL G KGE+   G G+ GPRG PGP GP GESR G PG  GS GP GPPG  G  
Sbjct: 1688 TPGERGLTGIKGEKGNPGVGTQGPRGPPGPAGPSGESRPGSPGPPGSPGPRGPPGHLGVP 1747

Query: 3033 GIRGPPGPPGYCDSSQCAS 3051
            G +GP G PGYCD S C++
Sbjct: 1748 GPQGPSGQPGYCDPSSCSA 1766



 Score =  600 bits (1546), Expect = e-171
 Identities = 360/969 (37%), Positives = 540/969 (55%), Gaps = 50/969 (5%)

Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149
            P  L+ +  +  S +++W+   G+  GYK+   PT   +   +L +       +++ L  
Sbjct: 33   PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKT-NQLNLQNTATKAIIQGLMP 91

Query: 1150 GTTYKVNVFGMFDGGESSPLVGQ----EMTTLSDTTV-MPILSSG------------MEC 1192
               Y V +       ES P  GQ    ++    D    + ++  G              C
Sbjct: 92   DQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVKFVC 151

Query: 1193 LTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQ 1252
             T A ADIV+LVDGSWSIGR NFR VR F+  +V  FD+G ++ +I LAQYSGDPR EW 
Sbjct: 152  QTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWH 211

Query: 1253 LNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKS 1312
            LNA   K  +++AV NLPYKGGNTLTG+ALN+I + +F+ +AG R    KIG+LITDGKS
Sbjct: 212  LNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKS 271

Query: 1313 QDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT 1372
            QDD+  PS+ L++ GVELFAIG+KNAD  EL+ IA++PD TH YNVA+F+ +  +V+ LT
Sbjct: 272  QDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTVVESLT 331

Query: 1373 INLCNSVKGPG-DLEA--------PSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS 1423
              LC+ V+    +++A        P+ L+ SE T RSF V+WT    +V++Y+V YYP  
Sbjct: 332  RTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTR 391

Query: 1424 GGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVS-LNI 1482
            GGK  E  V    +STVLK+L   TEY + V+++     SE L+GTE TL +P+ S L +
Sbjct: 392  GGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLL 451

Query: 1483 YDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA 1542
            YDV   +M V+W  V GA+GY++ Y P+ +      KE+++G T  D++L+ L+PNTEY 
Sbjct: 452  YDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT 511

Query: 1543 VTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKT 1602
            VTV A+  +  S+PVT +E TL L  P++L++ +V  ++  + W+P   ++  Y + Y  
Sbjct: 512  VTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNN 571

Query: 1603 PE-EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNL 1661
             +  ++ EVEVD   T+  LK L   T YT+++ +++DEG+S P+T   TT  VPA   L
Sbjct: 572  ADGTEINEVEVD-PITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYL 630

Query: 1662 KITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYE 1721
            +I EVT++ FR TW   ++D  L+++ W P       E +L  ++++ V E L P T YE
Sbjct: 631  EIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYE 690

Query: 1722 VSITAIYPDESESDDLIGSERTL------PILT-------TQAPKSGPRNLQVYNATSNS 1768
            VS+ A+  D SES+ +     TL      P  T       T   ++G RNL V + T++S
Sbjct: 691  VSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSS 750

Query: 1769 LTVKWDPASGRVQKYRITYQPSTGEGNEQ---TTTIGGRQNSVVLQKLKPDTPYTITVSS 1825
            L VKWD +   VQ++R+TY  + G+  E+   T  + G QN+++L+ L PDT Y +TV+ 
Sbjct: 751  LRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTP 810

Query: 1826 LYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAP-AAGG 1884
            +Y DGEG  ++  GKT P +  +NLRV +   + L + WD      + Y++ Y P +  G
Sbjct: 811  IYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPG 870

Query: 1885 PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYN 1944
            P     +  + N  ++ NL     Y V +      G     +   +TL  G+  N+Q  +
Sbjct: 871  PTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVT-NLQAKH 929

Query: 1945 PTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNL 2004
                SL   W         YRVV   +   +  ES V  G TR      L PD+ Y +++
Sbjct: 930  VEMTSLCAHWQ-VHRHATAYRVVIESLQDRQKQESTVGGGTTRHC-FYGLQPDSEYKISV 987

Query: 2005 VALYSDGEG 2013
                 + EG
Sbjct: 988  YTKLQEIEG 996



 Score =  420 bits (1079), Expect = e-116
 Identities = 313/1027 (30%), Positives = 481/1027 (46%), Gaps = 90/1027 (8%)

Query: 5   LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
           LPP LA +      + ++ +V PP+ L + +I  +++ +SW  P     GY++ V PT+ 
Sbjct: 13  LPPFLAIV---YFCTIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG 69

Query: 65  GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTI---QTGSSTKPV 121
           G T +  L  + T+ ++  L+P+  Y V I +Y++ +ES P  GQ  I   +     KP 
Sbjct: 70  GKTNQLNLQNTATKAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPR 129

Query: 122 EK--------KPGKTEIQK--CSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFD 171
            K        +P   E  K  C   A  D+V LVDGSWS+GR NF+ +  F+  LV+AFD
Sbjct: 130 VKVVDRGNGSRPSSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFD 189

Query: 172 IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTF 231
           +G EKTR+G+ QYS D R E++LN +  +DE++ A++ +PYKGGNT+TG A++Y+ +N+F
Sbjct: 190 VGSEKTRIGLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSF 249

Query: 232 TESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTP 291
              AG+R G  K+ I+ITDGKSQD++  P+R LR  GVE+F++G+K AD  EL++IAS P
Sbjct: 250 KPEAGSRTGVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEP 309

Query: 292 SLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGEL-VSGEEVVEPPSNLIAMEVSSKYV 350
              HV+NVA FD +  +   +   +CS V+EQ  E+  S   +  PP+ LI  EV+++  
Sbjct: 310 DSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSF 369

Query: 351 KLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM 410
            +NW  +P  V  Y+V+  P   G     +  G  ++T+ +++L + TEYQI+V A+   
Sbjct: 370 MVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTV-LKNLMSLTEYQIAVFAIYAH 428

Query: 411 TSSEPISIMEKTQPMKVQVE------CSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLE 464
           T+SE +   E T  + +  +          + +K D V    G Y I  A   +  A  E
Sbjct: 429 TASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASG-YLILYAPLTEGLAGDE 487

Query: 465 VLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMT 524
              K  +I      I L      P+TE+T+  +            F        TG+  T
Sbjct: 488 ---KEMKIGETHTDIELSGLL--PNTEYTVTVYA----------MFGEEASDPVTGQETT 532

Query: 525 YVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSD-VEIFAVGVKDAVRSE 583
                +  P     SNV      +T   +S       I   N+D  EI  V V       
Sbjct: 533 LA---LSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPITTFP 589

Query: 584 LEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD-LSFSE 642
           L+ + +P  E  +     +D  Q               + L  +     VP +  L   E
Sbjct: 590 LKGL-TPLTEYTIAIFSIYDEGQ--------------SEPLTGVFTTEEVPAQQYLEIDE 634

Query: 643 VTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVT 702
           VT+  F+  W P   +   + + +    G     VV      S V+  L+P T Y V++ 
Sbjct: 635 VTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLL 694

Query: 703 AEYEDGFSIPLA--------------------GEETTEEVKGAPRNLKVTDETTDSFKIT 742
           A  +DG    +                         T   +   RNL V DETT S ++ 
Sbjct: 695 AVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVK 754

Query: 743 WTQAPGRVLRYRIIYRPVAGGESRE----VTTPPNQRRRTLENLIPDTKYEVSVIPEYFS 798
           W  +   V ++R+ Y    G    E    V  P +Q    L+ L+PDT+Y+V+V P Y  
Sbjct: 755 WDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTD 814

Query: 799 GPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA-GGETQ 857
           G G  ++    T    G P++LRVS+   + ++++W      VK Y + Y PV+  G T 
Sbjct: 815 GEGVSVSAPGKTLPSSG-PQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTL 873

Query: 858 EVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917
           E  V  D    ++  L  G  Y + + A  ASG  DAL G   TL       +L  K + 
Sbjct: 874 ETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFL--GVTNLQAKHVE 931

Query: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977
            TS+ A+W         YRV  +SL  D    E  +           LQP+++Y+ISV+ 
Sbjct: 932 MTSLCAHW-QVHRHATAYRVVIESL-QDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYT 989

Query: 978 TYSSGEG 984
                EG
Sbjct: 990 KLQEIEG 996



 Score =  417 bits (1073), Expect = e-116
 Identities = 298/909 (32%), Positives = 445/909 (48%), Gaps = 64/909 (7%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            +V G+  V PP+ L    +S   ++++W        GYK+++TP T+G + + L++    
Sbjct: 25   IVQGQ--VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTP-TSGGKTNQLNLQNTA 81

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEP------ISIMEKTQPMKVQVEC--------- 431
            T   ++ L  D  Y + + A      S+P      I  +EK +  K +V+          
Sbjct: 82   TKAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRP 141

Query: 432  SRGVDIK--------ADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQ 483
            S   ++K        ADIV LVDGS+SIG  NF  VR FLE LV +F++   + +I L Q
Sbjct: 142  SSPEEVKFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQ 201

Query: 484  YSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK 543
            YS DP  E+ L  F+  +++IEA+   PY+GG+T TG A+ Y+ E  F P  GSR+ V K
Sbjct: 202  YSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSK 261

Query: 544  VMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFD 603
            + ILITDGKS D    P+  LR S VE+FA+GVK+A  +EL+ IAS P  THV+ V +FD
Sbjct: 262  IGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFD 321

Query: 604  AFQRISFELTQSICLRIEQELAAIKKKAYV---PPKDLSFSEVTSYGFKTNWSPAGENVF 660
                +   LT+++C R+E++   IK  A+    PP +L  SEVT+  F  NW+ A  NV 
Sbjct: 322  LMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVE 381

Query: 661  SYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTE 720
             Y + Y    G     VV   + +S VL +L   T Y + V A Y    S  L G ETT 
Sbjct: 382  KYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTL 441

Query: 721  EVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVA---GGESREVTTPPNQRRR 777
             +  A  +L + D T +S ++ W   PG    Y I+Y P+     G+ +E+         
Sbjct: 442  ALPMA-SDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPLTEGLAGDEKEMKIGETHTDI 499

Query: 778  TLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGA 837
             L  L+P+T+Y V+V   +      P+TG   T  +   PR+LR+S+  +++ +L+W   
Sbjct: 500  ELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLAL-SPPRNLRISNVGSNSARLTWDPT 558

Query: 838  PGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFG 897
              ++  Y + Y    G E  EV V   TT   L+GL   T+Y +++ ++Y  G  + L G
Sbjct: 559  SRQINGYRIVYNNADGTEINEVEVDPITT-FPLKGLTPLTEYTIAIFSIYDEGQSEPLTG 617

Query: 898  EGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDA 957
              TT EE  + Q L   ++T  S    W         +++ W  +Y    T E  L E+ 
Sbjct: 618  VFTT-EEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGG-KTEEVVLKEEQ 675

Query: 958  IHTMIENLQPETKYRISVFATYSSG-EGEPLTG-----------DATTELSQDSKT---- 1001
               +IE L+P T+Y +S+ A    G E E +T             ATT +   S T    
Sbjct: 676  DSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQ 735

Query: 1002 -----LKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMV---AKVPPTVTSTVL 1052
                 L V +ET +++RV W  +   V  +RV Y    G  ++ V     VP +  + +L
Sbjct: 736  TGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLL 795

Query: 1053 KRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG 1112
            K L P T Y +TV PIY  GEG      G T      P+NL+ S+   +  R+TW+P   
Sbjct: 796  KPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITWDPPSS 854

Query: 1113 EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQ 1172
             VKGY++ + P        E  VG   NT+++  L +G  Y V +F     G S  L G 
Sbjct: 855  PVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGM 914

Query: 1173 EMTTLSDTT 1181
              T     T
Sbjct: 915  VKTLFLGVT 923



 Score =  338 bits (867), Expect = 5e-92
 Identities = 227/772 (29%), Positives = 375/772 (48%), Gaps = 37/772 (4%)

Query: 637  DLSFSEVTSYGFKTNWS--PAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPE 694
            DL   +VT    +  W   P        +    E    DE  +    + T + LS L P 
Sbjct: 448  DLLLYDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPN 507

Query: 695  TLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYR 754
            T Y V V A + +  S P+ G+ETT  +   PRNL++++  ++S ++TW     ++  YR
Sbjct: 508  TEYTVTVYAMFGEEASDPVTGQETTLALS-PPRNLRISNVGSNSARLTWDPTSRQINGYR 566

Query: 755  IIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814
            I+Y    G E  EV   P      L+ L P T+Y +++   Y  G   PLTG   TEEV 
Sbjct: 567  IVYNNADGTEINEVEVDPITTF-PLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVP 625

Query: 815  GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLK 874
               + L + + TT + +++W         + + + PV GG+T+EV ++ +  + V++GL+
Sbjct: 626  AQ-QYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLE 684

Query: 875  EGTQYALSVTALYASGA-GDALFGEGTTLEE-------------------RGSPQDLVTK 914
             GT+Y +S+ A+   G+  + +   GTTL+                    +   ++LV  
Sbjct: 685  PGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVG 744

Query: 915  DITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDT---GEKNLPEDAIHTMIENLQPETKY 971
            D T +S+   W  +   V+ +RV++ +   D +    G   +P    + +++ L P+T+Y
Sbjct: 745  DETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804

Query: 972  RISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
            +++V   Y+ GEG  ++    T  S   + L+V EE  N +R+TW P    V  YR+VY+
Sbjct: 805  KVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYK 864

Query: 1032 PHG-RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSP 1090
            P    G  +   V   + + ++  L     Y++ +      G      G   T   F   
Sbjct: 865  PVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTL--FLGV 922

Query: 1091 RNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAG 1150
             NL+     M+S    W+        Y+V       DR+  E  VG          L+  
Sbjct: 923  TNLQAKHVEMTSLCAHWQ-VHRHATAYRVVIESL-QDRQKQESTVGGGTTRHCFYGLQPD 980

Query: 1151 TTYKVNVFGMFDGGESSPLVGQEMTTLSDT---TVMPILSSGMECLTRAEADIVLLVDGS 1207
            + YK++V+      E   +   E T    T   T  P +    E    A+AD+V +VDGS
Sbjct: 981  SEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGS 1040

Query: 1208 WSIGRANFRTVRSFISRIVEVFD-IGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAV 1266
            WSIG  NF  + SF+   V   + IG    Q+A+ Q++ DPRTE++LNA++ K++LL A+
Sbjct: 1041 WSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAI 1100

Query: 1267 ANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDE 1326
             ++ YKGGNT TG A+ ++R   F  ++G R    K+ V+ITDG+SQDDV   S++++ +
Sbjct: 1101 KHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDDVNKISREMQLD 1160

Query: 1327 GVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNS 1378
            G  +FAIG+ +AD  EL  I + P   H + V DF++  +I D+L   +C +
Sbjct: 1161 GYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELITFVCET 1212



 Score =  195 bits (495), Expect = 7e-49
 Identities = 108/265 (40%), Positives = 156/265 (58%), Gaps = 4/265 (1%)

Query: 55   YRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTI-TSYDEVEESVPVIGQLTIQ 113
            YR+ ++   D   +E T+   TT      L P++EY +++ T   E+E   P +  +   
Sbjct: 948  YRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEG--PSVSIMEKT 1005

Query: 114  TGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFD-I 172
                T+P    P     ++   +A  DLVF+VDGSWS+G  NF  I+ F+ + V A + I
Sbjct: 1006 QSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKI 1065

Query: 173  GEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFT 232
            G + T+V +VQ++ D RTEF LN Y  ++ LL AIK I YKGGNT TG AI Y+    FT
Sbjct: 1066 GTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFT 1125

Query: 233  ESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPS 292
              +G R G PKV ++ITDG+SQD+V   +RE++  G  +F++G+  AD  EL  I S PS
Sbjct: 1126 AESGTRRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIGSKPS 1185

Query: 293  LNHVFNVANFDAIVDIQNEIISQVC 317
              HVF V +FDA   I++E+I+ VC
Sbjct: 1186 ARHVFFVDDFDAFKKIEDELITFVC 1210



 Score =  181 bits (458), Expect = 1e-44
 Identities = 128/402 (31%), Positives = 201/402 (50%), Gaps = 28/402 (6%)

Query: 299  VANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSP 358
            + N  + +D   +I +   SG  + L  +V  + +    +NL A  V    +  +W    
Sbjct: 886  ITNLLSGMDYNVKIFASQASGFSDALTGMV--KTLFLGVTNLQAKHVEMTSLCAHWQVHR 943

Query: 359  SPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISI 418
               T Y+V++  +    +Q + +VG  TT      L  D+EY+ISV           +SI
Sbjct: 944  H-ATAYRVVIESLQDRQKQES-TVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSI 1001

Query: 419  MEKTQPMKVQ-------VECSRGV--DIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKS 469
            MEKTQ +  +       +  ++ V    KAD+VF+VDGS+SIG  NF K+ +FL   V +
Sbjct: 1002 MEKTQSLPTRPPTFPPTIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGA 1061

Query: 470  F-EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVRE 528
              +I  +  Q+++VQ++ DP TEF L  +   E +++AI    Y+GG+T TGKA+ YVR+
Sbjct: 1062 LNKIGTDGTQVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGNTKTGKAIKYVRD 1121

Query: 529  KIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIA 588
             +F    G+R  +PKV+++ITDG+S D     + +++     IFA+GV DA  SEL +I 
Sbjct: 1122 TLFTAESGTRRGIPKVIVVITDGRSQDDVNKISREMQLDGYSIFAIGVADADYSELVSIG 1181

Query: 589  SPPAETHVFTVEDFDAFQRISFELTQSICLRIEQ----------ELAAIKKKAYVPPKDL 638
            S P+  HVF V+DFDAF++I  EL   +C               +LA  K        + 
Sbjct: 1182 SKPSARHVFFVDDFDAFKKIEDELITFVCETASATCPVVHKDGIDLAGFKMMEMFGLVEK 1241

Query: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEP 680
             FS V       +  P   NVF  +  +K+A        + P
Sbjct: 1242 DFSSVEG----VSMEPGTFNVFPCYQLHKDALVSQPTRYLHP 1279



 Score =  156 bits (394), Expect = 3e-37
 Identities = 95/309 (30%), Positives = 154/309 (49%), Gaps = 15/309 (4%)

Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFT 2260
            T L  NV    + QI W       +P      Y+L ++P  G +  ++ ++ + T     
Sbjct: 34   TRLRYNVISHDSIQISWK------APRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQ 87

Query: 2261 GLSPDTDYGVTVFVQTPNLEGPGVS-------VKEHTTVKPTEAPTEPPTPPPPPTIPPA 2313
            GL PD +Y V +     + E            +++    KP     +      P +    
Sbjct: 88   GLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEV 147

Query: 2314 RDVCKG-AKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEV 2372
            + VC+  A ADIV L D SWSIG  NF  V  F+ N V  FD +     ++   QYS + 
Sbjct: 148  KFVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFD-VGSEKTRIGLAQYSGDP 206

Query: 2373 KSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVV 2432
            + E+ LN ++ K   + A++N+ Y+GGNT TG AL +I E     E+G R  V K+ +++
Sbjct: 207  RIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILI 266

Query: 2433 TDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKI 2492
            TDG+SQD++   +  +++SG  +F +GV + D NEL  IAS+P   HV+ V +F+    +
Sbjct: 267  TDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNVAEFDLMHTV 326

Query: 2493 EDNLITFVC 2501
             ++L   +C
Sbjct: 327  VESLTRTLC 335



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 31/64 (48%), Positives = 34/64 (53%), Gaps = 5/64 (7%)

Query: 2742 TQDSVGPPGPPGPAGG--PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799
            TQ   GPPGP GP+G   PG+ GP G     G  GPPG  G  GP GP G PG   P+  
Sbjct: 1708 TQGPRGPPGPAGPSGESRPGSPGPPGS---PGPRGPPGHLGVPGPQGPSGQPGYCDPSSC 1764

Query: 2800 SIPG 2803
            S  G
Sbjct: 1765 SAYG 1768



 Score = 53.1 bits (126), Expect = 4e-06
 Identities = 24/86 (27%), Positives = 43/86 (50%)

Query: 1383 GDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLK 1442
            G +  P+ L  +  +H S ++SW  P      YK+   P SGGK  +  +    T  +++
Sbjct: 28   GQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQ 87

Query: 1443 DLKPETEYVVNVYSVVEDEYSEPLKG 1468
             L P+  Y V + +  +D+ S+P +G
Sbjct: 88   GLMPDQNYTVQIIAYNKDKESKPAQG 113



 Score = 37.7 bits (86), Expect = 0.18
 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 4/94 (4%)

Query: 2019 QGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRN 2078
            QG+  P   P  LR    + +S+ ++W    G    Y+++ +PT G   ++   +     
Sbjct: 27   QGQVAP---PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTAT 82

Query: 2079 NVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGR 2112
              I+Q L PD  Y + +IA  +D +     G  R
Sbjct: 83   KAIIQGLMPDQNYTVQIIAYNKDKESKPAQGQFR 116



 Score = 37.4 bits (85), Expect = 0.23
 Identities = 21/95 (22%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 1750 QAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVV 1809
            Q   + P  L+    + +S+ + W    G+   Y++   P++G G      +       +
Sbjct: 27   QGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAI 85

Query: 1810 LQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844
            +Q L PD  YT+ + +   D E     G+ + K L
Sbjct: 86   IQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDL 120



 Score = 35.8 bits (81), Expect = 0.67
 Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 1/74 (1%)

Query: 1948 NSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVAL 2007
            +S+ + W    G    Y+++ +P  G + ++  +    T+ + ++ L+PD  Y+V ++A 
Sbjct: 44   DSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAI-IQGLMPDQNYTVQIIAY 102

Query: 2008 YSDGEGNPSPAQGR 2021
              D E  P+  Q R
Sbjct: 103  NKDKESKPAQGQFR 116


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  439 bits (1129), Expect = e-122
 Identities = 277/771 (35%), Positives = 385/771 (49%), Gaps = 67/771 (8%)

Query: 2317 CKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEF 2376
            CK    D+VFL D S S+G ++F KV +++ N V  F E+ P   +V  V+YSD   + F
Sbjct: 32   CKSVHYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTF-EVGPDRTRVGVVRYSDRPTTAF 90

Query: 2377 KLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMR---KNVPKVLVVVT 2433
            +L  +  +     A + + Y GGNT TG AL +I  +  +  +G R   +   +V +++T
Sbjct: 91   ELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLT 150

Query: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIE 2493
            DGRSQD V  AA    ++G  +F VGV +    EL  IAS+P   HVF V DF + +KI 
Sbjct: 151  DGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIR 210

Query: 2494 DNLITFVCETATSSCPLIYLDG----YTSPGFKMLEAYNLTEKNFASVQGV--SLESGSF 2547
              L   +CE     CP + ++G    +T+ G K +  ++L +    SV+ +    E+G+ 
Sbjct: 211  GKLRRRLCENVL--CPSVRVEGDRFKHTNGGTKEITGFDLMD--LFSVKEILGKRENGAQ 266

Query: 2548 PSYSAYRIQKNAF-VNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKP 2606
             SY    ++  +F V Q T D+ P GLP  Y  +  FR    +  + + IWQ+ D+   P
Sbjct: 267  SSY----VRMGSFPVVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIP 322

Query: 2607 QVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDC 2666
            QV +  D  +K + +       +   V F    V  LF   +HK+ + + +++V ++IDC
Sbjct: 323  QVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDC 382

Query: 2667 YEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSR 2726
              +    I+E  NI   G  ++GK L  +     F +Q   I C       + CCDIPS 
Sbjct: 383  ALVQTLPIEERENIDIQGKTVIGKRLY-DSVPIDFDLQRIVIYCDSRHAELETCCDIPS- 440

Query: 2727 RDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAK--------------GPRGERGISGA 2772
               G C               PP PP     PG++              G +GE G++G 
Sbjct: 441  ---GPCQV------TVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGP 491

Query: 2773 IGPPGPRGDIGPPGPQGPPGPQGPNG-LSI-PGEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830
            +G PGP+GDIG  GP G PGP+G  G + I P  QG +G KG  G PG PGR G+ G+ G
Sbjct: 492  MGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRG 551

Query: 2831 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGK---------------PG 2875
             PG +G PG  G  G  G  GP G PGPPG  G+PG+ G  G+               PG
Sbjct: 552  EPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPG 611

Query: 2876 KPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPN 2932
            KPGD    GRPGPSG+ G +G++GD+            V ++ + G+        +Q   
Sbjct: 612  KPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671

Query: 2933 DYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT- 2991
                +R   GP G  GPPG  G RG+ G  G PG PG  G+QGPPG  G+PG  G  G+ 
Sbjct: 672  GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731

Query: 2992 GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G  G  G PG PGP G   TGPPG  G  GPPGPPG  G  G RG  G PG
Sbjct: 732  GLPGEIGFPGKPGPPGP--TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780



 Score =  264 bits (675), Expect = 9e-70
 Identities = 154/345 (44%), Positives = 181/345 (52%), Gaps = 47/345 (13%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERG---ISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IP 2802
            GPPG  G  G  GA GPRGE G   + G  G PG  GD GP GPQGP GP+GP G +  P
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332

Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPG---PPGPMGPPGDRGFTGKDGA---------- 2849
            G  G  G  G  G+ G  G  G+PGLPG   P GP G PG++G  GK+G           
Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392

Query: 2850 --------MGPRGPPGPPGSPGSPGVTG---------PSGKPGKPGDHGRPGPSGLKGEK 2892
                     G +GPPG  G PG PG+ G         P G PG+ G  G PGP G  G  
Sbjct: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 1452

Query: 2893 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-QSSRNQPGPPGPPGP-- 2949
            G RG+  S   +R   R + E+L      R   +L Q+P  Y +SS+ +PGPPGPPG   
Sbjct: 1453 GLRGESPSMETLR---RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509

Query: 2950 -PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTG---SSGPRGLPGPPGP 3005
             PG AG  GEPG  G+ G  G  G  GP GERG  G+ G  G G     GP G+PG PG 
Sbjct: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569

Query: 3006 QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 3050
             G ++ G PG  G +G  GP G PG   + GPPGPPG CD SQCA
Sbjct: 1570 PGYAKDGLPGIPGPQGETGPAGHPG---LPGPPGPPGQCDPSQCA 1611



 Score =  247 bits (630), Expect = 1e-64
 Identities = 142/314 (45%), Positives = 164/314 (52%), Gaps = 67/314 (21%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIPGEQ 2805
            G PG PG  G PG  GP G  GI+GA GPPG +G    PG +GPPGPQGP+GL  IPGE+
Sbjct: 1186 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGLPGIPGEE 1242

Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------PGPP 2859
            G++G  G  G PG PG+ G PGLPGP G  GPPG +G TG  GA GPRG       PG  
Sbjct: 1243 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 1302

Query: 2860 GSPGSPGVTGPS------------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
            G PG  G TGP+            GK G PG  G PGPSG  G+KG +G+  S  +    
Sbjct: 1303 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---- 1358

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967
                                             PG  GP GPPG  G +G PG  G PG 
Sbjct: 1359 ---------------------------------PGFLGPRGPPGEPGEKGVPGKEGVPGK 1385

Query: 2968 PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGP 3022
            PG PG +   GERG PG KG++G  G  G  G PG PG +G +      G PG  G  GP
Sbjct: 1386 PGEPGFK---GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 1442

Query: 3023 PGPPGRPGNSGIRG 3036
            PGPPG+PG  G+RG
Sbjct: 1443 PGPPGQPGFPGLRG 1456



 Score =  238 bits (608), Expect = 5e-62
 Identities = 143/330 (43%), Positives = 165/330 (50%), Gaps = 35/330 (10%)

Query: 2748 PPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQG 2806
            PPGPPG  G PG KG +G  G  G  G  G +G+ GPPG  GPPG  GP G     G  G
Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGP------MGPPGDRGFTGKDGAMGPRGPPGPPG 2860
              G KGD G PG+PG  G PG PGPPG        GPPG +G  GK+G  GP+GP G PG
Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237

Query: 2861 SPGSPGVTGPSGKPGKPGD---HGRP---------GPSGLKGEKGDRGDIASQNMMRAVA 2908
             PG  G  G  GKPG PG+    G P         GP G KG  GD G    +    A+ 
Sbjct: 1238 IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 1297

Query: 2909 RQVCEQL-----ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGG 2963
                E L      +G          + P     S   PG PGP G PG  G++GE G  G
Sbjct: 1298 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357

Query: 2964 RPGF------PGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE-SRTG 3012
             PGF      PG PG +G PG+ G+PG+ GE G     G  G +G  GPPG +G+    G
Sbjct: 1358 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG 1417

Query: 3013 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             PG  G  G  GP G PG +G  GPPGPPG
Sbjct: 1418 IPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447



 Score =  235 bits (600), Expect = 4e-61
 Identities = 143/341 (41%), Positives = 167/341 (48%), Gaps = 45/341 (13%)

Query: 2740 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAI----------GPPGPRGDIGPPGPQG 2789
            T  Q   GP G  GP G  G  GP G  G+ G++          G PGPRG  G PGP G
Sbjct: 616  TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675

Query: 2790 PPGPQGPNGLS-IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG 2848
              GP GP G    PG QG +G KGD G PG+PG  G  G PGPPG  GPPG  G  G  G
Sbjct: 676  ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPG 735

Query: 2849 AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP---GPSGLKGEKGDRGDIASQNMMR 2905
             +G  G PGPPG  G PG  GP+G PG PG  G P   G  GL G+ G RG+I  Q +  
Sbjct: 736  EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG 795

Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 2965
                +  E  + G    F  +  +     +  + + G  G PG  G  G +GE GP G P
Sbjct: 796  RPGEK-GEAGLPGAPG-FPGVRGE-----KGDQGEKGELGLPGLKGDRGEKGEAGPAGPP 848

Query: 2966 GFPGT----------PGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE--- 3008
            G PGT          PG QGP GE+G PG  GE G     G  GP+G  GPPG +G+   
Sbjct: 849  GLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGA 908

Query: 3009 -------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
                      G PG  G+ GP GPPG  G  G+RG PG  G
Sbjct: 909  HGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 949



 Score =  229 bits (585), Expect = 2e-59
 Identities = 144/365 (39%), Positives = 160/365 (43%), Gaps = 77/365 (21%)

Query: 2733 PAFPNSCTCTQD-SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPP 2791
            P  P S     D  +G  GPPGP+G PG KG  G RG+ G  GP GP G  G PG  G  
Sbjct: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER 1089

Query: 2792 GPQGPNGLSI----------------------PGEQGRQGMKGDAGEPGLPGRTGT---- 2825
            GP G  GLS                       PG  G  G KGD G PG PGR GT    
Sbjct: 1090 GPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKK 1149

Query: 2826 -----PGLPGPPGPMGPPGDRGFTGKDGA---------------MGPRGPPGPPGSPGSP 2865
                 PGLPGPPG  GP G +G  G DG                MGP G PGPPG+ G  
Sbjct: 1150 GEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 1209

Query: 2866 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925
            G  GP G  G PG  G PGP G  G  G                      I G+  +  +
Sbjct: 1210 GAAGPPGIQGSPGKEGPPGPQGPSGLPG----------------------IPGEEGKEGR 1247

Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 2985
                 P        +PG PGP G  G  G +G  G  G PG  G  G  G PG+ GLPG+
Sbjct: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307

Query: 2986 KGERG-TGSSGPRGLPGPPGPQGE-------SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037
             G+ G TG  GP+G  GPPG  G          +G PG  GS+G  G PG PG  G RGP
Sbjct: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGP 1367

Query: 3038 PGPPG 3042
            PG PG
Sbjct: 1368 PGEPG 1372



 Score =  228 bits (580), Expect = 9e-59
 Identities = 156/398 (39%), Positives = 183/398 (45%), Gaps = 101/398 (25%)

Query: 2747 GPPGPPGPAGG----------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 2796
            GP GPPG  G           PG +GP+GE+G  G  G PG +G  G  GPQGP GP G 
Sbjct: 843  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 902

Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR--- 2853
             G     ++G  G  G AG PG PG  G PG  GPPG +G PG RG  GKDG  G +   
Sbjct: 903  KG-----QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957

Query: 2854 ------GPPGPPGSPGSPGVTGP--SGKPGKPGDHGRPGPSGLKGEKGDRGDI-ASQNMM 2904
                  GP GP G PG+PG+ GP   GK G+PG  G PG  G  G K   G +  S+N  
Sbjct: 958  GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC- 1016

Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQP-----GPPGPPGPP---GSAGAR 2956
                       + GQ  + ++    IP     SR  P     GPPGP GPP   GS G+R
Sbjct: 1017 ----------ALGGQCVKGDRGAPGIPGS-PGSRGDPGIGVAGPPGPSGPPGDKGSPGSR 1065

Query: 2957 GEP------GPGGRPGFPGTPGMQGPP--------------------------------- 2977
            G P      GP GR G PG PG +GPP                                 
Sbjct: 1066 GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLP 1125

Query: 2978 ------GERGLPGEKGERGT----GSSGPRGLPGPP---GPQG-ESRTGPPGSTGSRGPP 3023
                  G++G+PG+ G  GT    G +GP GLPGPP   GPQG +   G  G  G +G  
Sbjct: 1126 GLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ 1185

Query: 3024 GPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            G PG PG  G  G PGPPG  D    A+ P   QG PG
Sbjct: 1186 GHPGVPGFMGPPGNPGPPG-ADGIAGAAGPPGIQGSPG 1222



 Score =  221 bits (564), Expect = 7e-57
 Identities = 151/385 (39%), Positives = 171/385 (44%), Gaps = 112/385 (29%)

Query: 2747 GPPGPPGPAGGPGAKGP------RGERGISG---AIGPPGPRGDIGPPGPQGPP--GPQG 2795
            GP GPPG  G PG +G       RGE+G +G   + GP GPRGD G PG  GPP  G  G
Sbjct: 928  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 987

Query: 2796 PNGL----SIPGEQGR-----------------QGMKGDAGEPGLPGRTGTPGLP----- 2829
              GL     +PG  G                  Q +KGD G PG+PG  G+ G P     
Sbjct: 988  EPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVA 1047

Query: 2830 GPPGPMGPPGDRGFTGK---DGAMGPRGPPGPPGSPGSPGVTGPSGKPG-----KPGD-- 2879
            GPPGP GPPGD+G  G     G  GP+GP G  G+PG+PG  GP GKPG      PGD  
Sbjct: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDIN 1107

Query: 2880 -----------HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLN 2928
                        G PG  GL G KGD+G                   + G+  R      
Sbjct: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKG-------------------VPGKPGR------ 1142

Query: 2929 QIPNDYQSSRNQPGPPGPPGPPGSA---------GARGEPGPGGRPGFPGTPGMQGPPGE 2979
                  +  + + GPPG PGPPG A         GA GE G  G  G PG PG  GPPG 
Sbjct: 1143 ---EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 1199

Query: 2980 RGLPGEKGERGT----------------GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGP 3022
             G PG  G  G                 G  GP GLPG PG +G E R G PG  G  G 
Sbjct: 1200 PGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK 1259

Query: 3023 PGPPGRPGNSGIRGPPGPPGYCDSS 3047
             G PG PG  G RGPPG  G+   S
Sbjct: 1260 AGEPGLPGPEGARGPPGFKGHTGDS 1284



 Score =  214 bits (545), Expect = 1e-54
 Identities = 155/428 (36%), Positives = 173/428 (40%), Gaps = 115/428 (26%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SI 2801
            Q   G  GP GP G PGAKG  G  G  GA G PG  G +G PGP GPPG  G  GL   
Sbjct: 885  QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGT 944

Query: 2802 PGEQGRQGMKGDAGEPGLPGRTG------TPGLPGPPGPM--GPPGDRGFTGKDGAMGP- 2852
            PG+ G +G KG AGE G PG  G       PGLPGPPG    G PG RG  G  G +G  
Sbjct: 945  PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 1004

Query: 2853 ----------------------RGPPGPPGSPGSPG-----VTGPSGKPGKPGDHGRPGP 2885
                                  RG PG PGSPGS G     V GP G  G PGD G PG 
Sbjct: 1005 AACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGS 1064

Query: 2886 SGLKGEKGDRG-----------------------DIASQNMMRAVARQVCEQLISGQMNR 2922
             GL G  G +G                        + S   +  +A+ VC     G    
Sbjct: 1065 RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPG- 1123

Query: 2923 FNQMLNQIPN--------------DYQSSRNQPGPPGPPGPPGSAG---------ARGEP 2959
                L  +P                 +  + + GPPG PGPPG AG         A GE 
Sbjct: 1124 ----LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEV 1179

Query: 2960 GPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----------------GSSGPRGLPGPP 3003
            G  G  G PG PG  GPPG  G PG  G  G                 G  GP GLPG P
Sbjct: 1180 GQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIP 1239

Query: 3004 GPQG----ESRTGPPGSTGSRGPPG------PPGRPGNSGIRGPPGPPGYCDSSQCASIP 3053
            G +G    + + GPPG  G  G PG        G PG  G  G  G PG    S    +P
Sbjct: 1240 GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLP 1299

Query: 3054 YNGQGYPG 3061
               +G PG
Sbjct: 1300 -GQEGLPG 1306



 Score =  211 bits (538), Expect = 7e-54
 Identities = 148/415 (35%), Positives = 167/415 (40%), Gaps = 134/415 (32%)

Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPP---------------GPAGGPGAKGPRGER 2767
            +P     G  P  P         +G PG P               GP G PG KG  GER
Sbjct: 721  VPGPPGPGGSPGLPGE-------IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER 773

Query: 2768 GISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-------SIPGEQGRQGMKGD------- 2813
            G  G  G PG RG+IG  G  G PG +G  GL        + GE+G QG KG+       
Sbjct: 774  GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833

Query: 2814 -----------AGEPGLPGRT-------------------GTPGLP------------GP 2831
                       AG PGLPG T                   G PGLP            GP
Sbjct: 834  GDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893

Query: 2832 PGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891
             GP GPPG +G  G  GA G  G PG PG  G+PG +GP G  G PG  G PG  G +GE
Sbjct: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953

Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951
            KG  G+  S   +                                 R  PG PG PGPPG
Sbjct: 954  KGAAGEEGSPGPV-------------------------------GPRGDPGAPGLPGPPG 982

Query: 2952 SAGARGEPGPGGRPGFPG-----------------------TPGMQGPPGERGLPGEKGE 2988
              G  GEPG  G PG PG                         G +G PG  G PG +G+
Sbjct: 983  K-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGD 1041

Query: 2989 RGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             G G +GP G  GPPG +G     G PG  G +GP G  G PGN G RGPPG PG
Sbjct: 1042 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096



 Score =  147 bits (370), Expect = 2e-34
 Identities = 75/184 (40%), Positives = 120/184 (65%), Gaps = 3/184 (1%)

Query: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQ 199
           DLVFL+D S SVG+ +F+ +  ++A LV  F++G ++TRVGVV+YS    T F L  +  
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 200 RDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARV---GFPKVAIIITDGKSQDE 256
           ++E+ AA +++ Y GGNT TGDA+ Y+   +F+  AG R     + +VAI++TDG+SQD 
Sbjct: 98  QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157

Query: 257 VEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQV 316
           V   A      G+ +F++G+  A  +EL++IAS P   HVF+V++F+AI  I+ ++  ++
Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217

Query: 317 CSGV 320
           C  V
Sbjct: 218 CENV 221



 Score =  140 bits (353), Expect = 2e-32
 Identities = 75/181 (41%), Positives = 107/181 (59%), Gaps = 3/181 (1%)

Query: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTK 499
           D+VFL+D S S+G  +F KVR ++  LV +FE+ P+R ++ +V+YS  P T F L  F  
Sbjct: 38  DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 500 VEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSN---VPKVMILITDGKSSDA 556
            E++  A     Y GG+TNTG A+ Y+  + F P  G R       +V IL+TDG+S D 
Sbjct: 98  QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157

Query: 557 FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616
             D A     + + IFAVGV +A++ ELE IAS P   HVF V DF+A  +I  +L + +
Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217

Query: 617 C 617
           C
Sbjct: 218 C 218



 Score =  133 bits (334), Expect = 3e-30
 Identities = 67/187 (35%), Positives = 112/187 (59%), Gaps = 3/187 (1%)

Query: 1199 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 1258
            D+V L+D S S+G+ +F  VR +++ +V+ F++GP R ++ + +YS  P T ++L     
Sbjct: 38   DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97

Query: 1259 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRAR---KIGVLITDGKSQDD 1315
            ++ +  A   L Y GGNT TG AL +I  ++F   AG RPR R   ++ +L+TDG+SQD 
Sbjct: 98   QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157

Query: 1316 VEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINL 1375
            V   +      G+ +FA+G+  A + EL+ IA++P   H ++V+DF ++ +I   L   L
Sbjct: 158  VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRL 217

Query: 1376 CNSVKGP 1382
            C +V  P
Sbjct: 218  CENVLCP 224



 Score =  108 bits (269), Expect = 1e-22
 Identities = 59/128 (46%), Positives = 67/128 (52%), Gaps = 13/128 (10%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            PA+  S   +Q   GPPGPPG  G PG  GP GE G  G  G  GP G IGP G +G  G
Sbjct: 1489 PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 1545

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
              G  G+ + GE G  G+ G  GEPG   + G PG+PGP G  GP G  G          
Sbjct: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGPAGHPGLP-------- 1596

Query: 2853 RGPPGPPG 2860
             GPPGPPG
Sbjct: 1597 -GPPGPPG 1603


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score =  427 bits (1098), Expect = e-119
 Identities = 249/665 (37%), Positives = 369/665 (55%), Gaps = 22/665 (3%)

Query: 1192 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEW 1251
            CL    AD+V LVDGSWSIG ++F+ V+ F++ ++  F+IGP +VQ+ L QYSGD +TEW
Sbjct: 172  CLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEW 231

Query: 1252 QLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGK 1311
             LN+   K+ +L AV  L YKGGNT TG+AL  +  QN +  AG+RP A K+ +L+TDGK
Sbjct: 232  DLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGK 291

Query: 1312 SQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDL 1371
            SQDDV   ++ LKD GV +FA+G+KNADE EL+++A+ P D   ++V DF  L  +   L
Sbjct: 292  SQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLL 351

Query: 1372 TINLCNSVKGPG------------DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEY 1419
            +  +C  ++G               L AP++LV+S+ T  S R+SWTP      +Y + +
Sbjct: 352  SRLICQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVW 411

Query: 1420 YPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVV- 1478
                GG  +E  V     ST L +L   TEY+V+V+ + E    E L+G   T P+P   
Sbjct: 412  RASRGGTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPR 471

Query: 1479 SLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPN 1538
            +L +  V P T+H+ WQP  GAT Y++   P         +EV++G    ++ L  L P 
Sbjct: 472  ALTLAAVTPRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRP--EVLLDGLEPG 529

Query: 1539 TEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIV 1598
             +Y V+VQ++     SE   +R  T  L  P+ L   DV+H    VFWE  P  VR   V
Sbjct: 530  RDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589

Query: 1599 RYKTPEEDVK-EVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPA 1657
             Y + E     + E   + TS +L  L S T YTV V+ ++  G S  +T + TT+  P+
Sbjct: 590  TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPS 649

Query: 1658 PTNLKITEVTSEGFRGTWDHGA-SDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNP 1716
            P+ L +TE+  +  +  W   A S V +Y+ITW P G     E  + G+  T V   L  
Sbjct: 650  PSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGR 709

Query: 1717 NTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPA 1776
            +T Y+V+I A Y D + SD +  S R  P   +++P   P NL + + T +SL V W P 
Sbjct: 710  HTEYDVTILAYYRDGARSDPV--SLRYTPSTVSRSP---PSNLALASETPDSLQVSWTPP 764

Query: 1777 SGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMT 1836
             GRV  Y +TY P++G G E++ ++ G ++ V L  L+  T Y + VS++Y  G    ++
Sbjct: 765  LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824

Query: 1837 GRGKT 1841
              G+T
Sbjct: 825  ATGQT 829



 Score =  355 bits (910), Expect = 5e-97
 Identities = 189/491 (38%), Positives = 275/491 (56%), Gaps = 46/491 (9%)

Query: 2500 VCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNA 2559
            V  T  ++CP +  DG + PGF ++ A++L EK +AS++GV++E  +F     + + K+A
Sbjct: 823  VSATGQTACPALRPDG-SLPGFDLMVAFSLVEKAYASIRGVAMEPSAFGGTPTFTLFKDA 881

Query: 2560 FVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTL 2619
             + +  +D++P  LPP +TI+ L RLLPETP + FA+WQ+T  D++P +GV+ D   K+L
Sbjct: 882  QLTRRVSDVYPAPLPPEHTIVFLVRLLPETPREAFALWQMTAEDFQPLLGVLLDAGKKSL 941

Query: 2620 SFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGN 2679
            ++F++D R  +Q  TFD +EV+ +F+GSFHKVH+ V    V++Y+DC ++ E+ + E G+
Sbjct: 942  TYFHRDPRAALQEATFDPQEVRKIFFGSFHKVHVAVGRSKVRLYVDCRKVAERPLGEMGS 1001

Query: 2680 ITTDGYEILGKLLKGE---RKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFP 2736
                G+  LG+L K       SAAFQ+Q   IVCS  W   DRCC++P+ RD   CPAF 
Sbjct: 1002 PPAAGFVTLGRLAKARGPRSSSAAFQLQMLQIVCSDTWADEDRCCELPASRDGETCPAFV 1061

Query: 2737 NSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 2796
            ++C+C+ ++ GPPGP G                     PPG  G  G PG QG PGP+GP
Sbjct: 1062 SACSCSSETPGPPGPQG---------------------PPGLPGRNGTPGEQGFPGPRGP 1100

Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856
                        G+KG+ G+ GLPG  G PG  G PG +G  G +G  G +G  G  GPP
Sbjct: 1101 -----------PGVKGEKGDHGLPGLQGHPGHQGIPGRVGLQGPKGMRGLEGTAGLPGPP 1149

Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLI 2916
            GP G  G  G  G SG+ G P   G  GP+GL G KG+RG+      +  + + V +   
Sbjct: 1150 GPRGFQGMAGARGTSGERGPP---GTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASH 1206

Query: 2917 SGQMNRFNQMLNQIPNDYQSSRNQPG--PPGPPGPPGSAGARGEPGPGGR----PGFPGT 2970
              + + F++   + P      + +PG  P G PG    A   GE G GGR     G PG 
Sbjct: 1207 VSKFDSFHEN-TRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGA 1265

Query: 2971 PGMQGPPGERG 2981
             G  G PG++G
Sbjct: 1266 VGQMGSPGQQG 1276



 Score =  302 bits (774), Expect = 3e-81
 Identities = 224/695 (32%), Positives = 336/695 (48%), Gaps = 24/695 (3%)

Query: 437  IKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKK 496
            + AD+VFLVDGS+SIG ++F +V+ FL  ++  FEI P++VQ+ L QYS D  TE+ L  
Sbjct: 176  VPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNS 235

Query: 497  FTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDA 556
             +  E ++ A+    Y+GG+T TG A+T+V  +   P+ G R    KV+IL+TDGKS D 
Sbjct: 236  LSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDD 295

Query: 557  FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616
                A  L++  V +FAVGVK+A  +EL  +ASPP +  V +V DF     ++  L++ I
Sbjct: 296  VHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLI 355

Query: 617  CLRIE-----QELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAA 670
            C R++     Q  AA      +P P  L  S+VTS   + +W+PA  +   Y I ++ + 
Sbjct: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASR 415

Query: 671  GDD--EVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
            G    EV V  PA+ST   L +L   T YLV+V   YE G    L G  TT  +   PR 
Sbjct: 416  GGTPREVVVEGPAASTE--LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLP-PPRA 472

Query: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTK 787
            L +   T  +  +TW  + G    Y +   P +  GE  E      +    L+ L P   
Sbjct: 473  LTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRD 531

Query: 788  YEVSVIPEYFSGP-GTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLV 846
            YEVSV  +   GP G+   G  A       PR L  SD +    ++ W GAP  V+   V
Sbjct: 532  YEVSV--QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRV 589

Query: 847  TYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERG 906
            TY    GG + +    G+ T+  L  L   T Y + VT LY  G    L G  TT ++  
Sbjct: 590  TYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT-KKAP 648

Query: 907  SPQDLVTKDITDTSIGAYW-TSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENL 965
            SP  L   ++   ++   W  +AP  V  Y+++W  L  +    E ++P +    ++  L
Sbjct: 649  SPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGL 707

Query: 966  QPETKYRISVFATYSSG-EGEP--LTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGK 1022
               T+Y +++ A Y  G   +P  L    +T        L +  ET ++++V+W P  G+
Sbjct: 708  GRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGR 767

Query: 1023 VVNYRVVYRP-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSG 1081
            V++Y + Y P  G G +    VP   +   L  LQ  T Y + V  IY  G  +    +G
Sbjct: 768  VLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATG 827

Query: 1082 TTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKG 1116
             TA     P         M +F +  E A   ++G
Sbjct: 828  QTACPALRPDGSLPGFDLMVAFSLV-EKAYASIRG 861



 Score =  199 bits (506), Expect = 3e-50
 Identities = 125/457 (27%), Positives = 227/457 (49%), Gaps = 58/457 (12%)

Query: 12  LGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFT 71
           LGA L    ++A       L   ++ E+ + M W +     +GY + V P      +E  
Sbjct: 17  LGATLGREQVQAS----GLLRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVI 72

Query: 72  LSASTTETLLSELVPETEYVVTITSY----------------DEVEESVPVIGQLTIQTG 115
           L+  T +  +  L P   Y + I                   D    S+    Q  + +G
Sbjct: 73  LTTKTPKATVGGLSPSKGYTLQIFELTGSGRFLLARREFVIEDLKSSSLDRSSQRPLGSG 132

Query: 116 SSTKPVEKKPGKTEIQ-----------------------KCSVSAWTDLVFLVDGSWSVG 152
           +  +P     G  + +                       +C      D+VFLVDGSWS+G
Sbjct: 133 AP-EPTPSHTGSPDPEQASEPQVAFTPSQDPRTPAGPQFRCLPPVPADMVFLVDGSWSIG 191

Query: 153 RNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPY 212
            ++F+ + DF+A++++ F+IG +K +VG+ QYS D +TE++LN    ++++LAA++++ Y
Sbjct: 192 HSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRY 251

Query: 213 KGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVF 272
           KGGNT TG A+ +++      +AG R    KV I++TDGKSQD+V   AR L+++GV VF
Sbjct: 252 KGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHTAARVLKDLGVNVF 311

Query: 273 SLGIKAADAKELKQIASTP---SLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVS 329
           ++G+K AD  EL+ +AS P   +++ V +     A+  + + +I Q   G   + G   +
Sbjct: 312 AVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAAA 371

Query: 330 -GEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTT 388
              + +  P++L+  +V+S  ++L+W P+P     Y ++      G+ +  +  GP  +T
Sbjct: 372 PALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAAST 431

Query: 389 LSVRDLSADTEYQISV---------SAMKGMTSSEPI 416
             + +L++ TEY +SV           ++G+ ++ P+
Sbjct: 432 -ELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPL 467



 Score =  178 bits (452), Expect = 6e-44
 Identities = 142/467 (30%), Positives = 211/467 (45%), Gaps = 22/467 (4%)

Query: 1655 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENL 1714
            +PAPT+L +++VTS   R +W         Y I W         E ++ G   +    NL
Sbjct: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNL 436

Query: 1715 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 1774
               T Y VS+  IY          G    L  L T AP   PR L +   T  ++ + W 
Sbjct: 437  ASRTEYLVSVFPIYEG--------GVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ 488

Query: 1775 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLY-PDGEGG 1833
            P++G    Y +   P++ +G E+   +   +  V+L  L+P   Y ++V SL  P+G   
Sbjct: 489  PSAGATH-YLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEA 547

Query: 1834 RMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPG 1893
            R   R +T  L   R+L   D S     V W+ A    R  ++ Y  + GG       PG
Sbjct: 548  RGI-RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG 606

Query: 1894 NTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQV-YNPTP-NSLD 1951
            N   A L  L   T+YTV V  +Y    GG ++ TGR   +      Q+     P +++ 
Sbjct: 607  NATSATLGPLSSSTTYTVRVTCLYP--GGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664

Query: 1952 VRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSD 2010
            + W   AP  VL Y++ ++P+ G   +  I VPGN     L  L   T Y V ++A Y D
Sbjct: 665  LAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRD 723

Query: 2011 GEGNPSPAQGR----TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 2066
            G     P   R    T+ RS P NL +  ET +SL V+W    G V  Y + Y+P  G  
Sbjct: 724  G-ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLG 782

Query: 2067 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRT 2113
             ++  +VPG R++V L  LQ  T Y++ V A+Y  G    ++  G+T
Sbjct: 783  PEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score =  177 bits (448), Expect = 2e-43
 Identities = 136/448 (30%), Positives = 205/448 (45%), Gaps = 12/448 (2%)

Query: 725  APRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIP 784
            AP +L ++  T+ S +++WT AP   L+Y I++R   GG  REV          L NL  
Sbjct: 379  APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGPAASTELHNLAS 438

Query: 785  DTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQY 844
             T+Y VSV P Y  G G  L G   T  +   PR L ++  T  T+ L+W  + G    Y
Sbjct: 439  RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPP-PRALTLAAVTPRTVHLTWQPSAGAT-HY 496

Query: 845  LVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLE 903
            LV  +P +  GE +E  V+      +L GL+ G  Y +SV +L      +A  G      
Sbjct: 497  LVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR-GIRARTP 555

Query: 904  ERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIE 963
                P+ L   D++  +   +W  AP  VR  RV++ S  +   +G+   P +A    + 
Sbjct: 556  TLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSS-EGGHSGQTEAPGNATSATLG 614

Query: 964  NLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGK 1022
             L   T Y + V   Y  G    LTG  TT+ +     L + E   + +++ W   AP  
Sbjct: 615  PLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSG 674

Query: 1023 VVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK----LRQ 1078
            V+ Y++ + P G GK     VP  + + VL  L   T YD+T+L  Y+ G       LR 
Sbjct: 675  VLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRY 734

Query: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPY 1138
             + +T SR   P NL  +  T  S +V+W P  G V  Y +T+ P         + V   
Sbjct: 735  -TPSTVSR-SPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGA 792

Query: 1139 DNTVVLEELRAGTTYKVNVFGMFDGGES 1166
             + V L +L+A T Y+V V  ++  G S
Sbjct: 793  RSHVTLPDLQAATKYRVLVSAIYAAGRS 820



 Score =  145 bits (367), Expect = 5e-34
 Identities = 102/326 (31%), Positives = 147/326 (45%), Gaps = 35/326 (10%)

Query: 2218 DTFCVKWSPHRAA-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVF--- 2273
            D   +KW     +   Y +++ P  G   QE+ +          GLSP   Y + +F   
Sbjct: 40   DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELT 99

Query: 2274 -------------------------VQTPNLEGPGVSVKEHTTVKPTEAPTEPP---TPP 2305
                                      Q P   G       HT     E  +EP    TP 
Sbjct: 100  GSGRFLLARREFVIEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEPQVAFTPS 159

Query: 2306 PPPTIP--PARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQV 2363
              P  P  P         AD+VFL D SWSIG  +F +V  F+ + +  F EI P  +QV
Sbjct: 160  QDPRTPAGPQFRCLPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPF-EIGPDKVQV 218

Query: 2364 SFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRK 2423
               QYS + ++E+ LN+ + K   L A++ +RY+GGNT TG ALT +  + L   +G+R 
Sbjct: 219  GLTQYSGDAQTEWDLNSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRP 278

Query: 2424 NVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIV 2483
               KV+++VTDG+SQD+V  AA V++  G +VF VGV + D  EL  +AS P +  V  V
Sbjct: 279  EAAKVVILVTDGKSQDDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASPPRDITVHSV 338

Query: 2484 DDFESFEKIEDNLITFVCETATSSCP 2509
             DF     +   L   +C+      P
Sbjct: 339  LDFLQLGALAGLLSRLICQRLQGGSP 364



 Score =  143 bits (360), Expect = 3e-33
 Identities = 124/454 (27%), Positives = 193/454 (42%), Gaps = 11/454 (2%)

Query: 1756 PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKP 1815
            P +L +   TS+S+ + W PA     KY I ++ S G G  +   + G   S  L  L  
Sbjct: 380  PTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRG-GTPREVVVEGPAASTELHNLAS 438

Query: 1816 DTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYK 1875
             T Y ++V  +Y  G G  + G   T PL   R L +   +  T+++ W  + G    Y 
Sbjct: 439  RTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG-ATHYL 497

Query: 1876 LFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMR 1934
            +  +PA+  G EE   +       +L  L+P   Y V+V  +             RT   
Sbjct: 498  VRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTL 557

Query: 1935 GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERL 1994
               R++   + + ++  V W+ AP PV   RV Y   +G    ++   PGN     L  L
Sbjct: 558  APPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQT-EAPGNATSATLGPL 616

Query: 1995 IPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAW-DHADGPVQ 2053
               T Y+V +  LY  G  +    +  T     P  L +     +++ +AW   A   V 
Sbjct: 617  SSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVL 676

Query: 2054 QYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDG---DGGHLTGN 2110
             Y+I ++P +G+      +VPG     +L  L   T Y +T++A Y DG   D   L   
Sbjct: 677  VYQITWTP-LGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYT 735

Query: 2111 GRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPME--AFVGEMTS 2168
              TV   PP N+ ++ E     +VSW P    VL Y + Y P     P +  +  G  + 
Sbjct: 736  PSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSH 795

Query: 2169 YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 2202
             TL +L  +T Y V V A Y +G S  ++  G T
Sbjct: 796  VTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score =  113 bits (283), Expect = 3e-24
 Identities = 94/332 (28%), Positives = 145/332 (43%), Gaps = 8/332 (2%)

Query: 1946 TPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLV 2005
            T +S+ + W PAP   L+Y +V+    G  P E +VV G      L  L   T Y V++ 
Sbjct: 389  TSSSIRLSWTPAPRHPLKYLIVWRASRGGTPRE-VVVEGPAASTELHNLASRTEYLVSVF 447

Query: 2006 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 2065
             +Y  G G        T P   PR L +   T  ++ + W  + G    Y +  SP    
Sbjct: 448  PIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAGATH-YLVRCSPASPK 506

Query: 2066 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG-NGRTVGLLPPQNIHI 2124
              +E   V   R  V+L  L+P   Y+++V ++    +G    G   RT  L PP+++  
Sbjct: 507  GEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGIRARTPTLAPPRHLGF 565

Query: 2125 SDEWYTRFRVSWDPSPSPVLGYKIVY-KPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVN 2183
            SD  +   RV W+ +P PV   ++ Y    G +       G  TS TL  L+ STTY V 
Sbjct: 566  SDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVR 625

Query: 2184 VYAQYDSGLSVPLTDQGTTLYL-NVTDLKTYQIGWDTFCVKW--SPHRAATSYRLKLSPA 2240
            V   Y  G S  LT + TT    + + L   ++  D   + W  +       Y++  +P 
Sbjct: 626  VTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPL 685

Query: 2241 DGTRGQEITVRGSETSHCFTGLSPDTDYGVTV 2272
               +  EI+V G+  +    GL   T+Y VT+
Sbjct: 686  GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTI 717



 Score =  106 bits (264), Expect = 4e-22
 Identities = 59/125 (47%), Positives = 69/125 (55%), Gaps = 20/125 (16%)

Query: 2937 SRNQPGPPGPPGPPG------SAGARGEPGPGGRPGFPGT------PGMQGPPGERGLPG 2984
            S   PGPPGP GPPG      + G +G PGP G PG  G       PG+QG PG +G+PG
Sbjct: 1067 SSETPGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPG 1126

Query: 2985 EKGERGT----GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPP---GPPGRPGNSGIRG 3036
              G +G     G  G  GLPGPPGP+G +   G  G++G RGPP   GP G PG  G RG
Sbjct: 1127 RVGLQGPKGMRGLEGTAGLPGPPGPRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERG 1186

Query: 3037 PPGPP 3041
              G P
Sbjct: 1187 EKGEP 1191



 Score =  106 bits (264), Expect = 4e-22
 Identities = 85/241 (35%), Positives = 89/241 (36%), Gaps = 63/241 (26%)

Query: 2829 PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888
            PGPPGP GPPG  G  G  G  G  GP GPPG  G  G  G  G  G PG  G PG  GL
Sbjct: 1071 PGPPGPQGPPGLPGRNGTPGEQGFPGPRGPPGVKGEKGDHGLPGLQGHPGHQGIPGRVGL 1130

Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948
            +G KG RG                                             G PGPPG
Sbjct: 1131 QGPKGMRG----------------------------------------LEGTAGLPGPPG 1150

Query: 2949 P---PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT------------GS 2993
            P    G AGARG  G  G PG  G  G+ GP GERG  GE     T              
Sbjct: 1151 PRGFQGMAGARGTSGERGPPGTVGPTGLPGPKGERGEKGEPQSLATLYQLVSQASHVSKF 1210

Query: 2994 SGPRGLPGPPGPQGESR----TGPPGSTGSRGPPGPPGRPGNSGI----RGPPGPPGYCD 3045
                    PP P  E +    T P GS G+R     PG  G  G     RG PG  G   
Sbjct: 1211 DSFHENTRPPMPILEQKLEPGTEPLGSPGTRSKALVPGEWGRGGRHLEGRGEPGAVGQMG 1270

Query: 3046 S 3046
            S
Sbjct: 1271 S 1271



 Score =  103 bits (256), Expect = 3e-21
 Identities = 80/275 (29%), Positives = 124/275 (45%), Gaps = 5/275 (1%)

Query: 902  LEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTM 961
            L+   +P  LV   +T +SI   WT AP     Y + W++        E  +   A  T 
Sbjct: 374  LDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR-EVVVEGPAASTE 432

Query: 962  IENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPG 1021
            + NL   T+Y +SVF  Y  G GE L G  TT      + L +   T  T+ +TW+P+ G
Sbjct: 433  LHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQPSAG 492

Query: 1022 KVVNYRVVYRPHG-RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGS 1080
               +Y V   P   +G++   +V       +L  L+P   Y+++V  + +  EG   +G 
Sbjct: 493  -ATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSL-RGPEGSEARGI 550

Query: 1081 GTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDN 1140
                     PR+L  SD +  + RV WE AP  V+  +VT+  + +    G+        
Sbjct: 551  RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTY-VSSEGGHSGQTEAPGNAT 609

Query: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMT 1175
            +  L  L + TTY V V  ++ GG SS L G+  T
Sbjct: 610  SATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTT 644



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 73/296 (24%), Positives = 109/296 (36%), Gaps = 17/296 (5%)

Query: 2016 SPAQGR-------TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 2068
            SP QG        TLP   P +L +   T++S+ ++W  A     +Y I++  + G    
Sbjct: 363  SPRQGPAAAPALDTLP--APTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPR 420

Query: 2069 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 2128
            E   V G   +  L  L   T Y ++V  +YE G G  L G   T  L PP+ + ++   
Sbjct: 421  E-VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVT 479

Query: 2129 YTRFRVSWDPSPSPV--LGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYA 2186
                 ++W PS      L       P G  E  E  VG      L  L P   Y+V+V +
Sbjct: 480  PRTVHLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGR-PEVLLDGLEPGRDYEVSVQS 538

Query: 2187 -QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTR 2244
             +   G         T        L    +  D   V W    R     R+    ++G  
Sbjct: 539  LRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGH 598

Query: 2245 GQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTE 2300
              +    G+ TS     LS  T Y V V    P   G   ++    T K   +P++
Sbjct: 599  SGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG--GGSSTLTGRVTTKKAPSPSQ 652



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 28/62 (45%), Positives = 30/62 (48%), Gaps = 12/62 (19%)

Query: 3000 PGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGY 3059
            PGPPGPQG     PPG       PG  G PG  G  GP GPPG         +P   QG+
Sbjct: 1071 PGPPGPQG-----PPGL------PGRNGTPGEQGFPGPRGPPGVKGEKGDHGLP-GLQGH 1118

Query: 3060 PG 3061
            PG
Sbjct: 1119 PG 1120



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 24/87 (27%), Positives = 44/87 (50%)

Query: 336 PPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLS 395
           PPSNL     +   ++++W P    V  Y +   P +    + ++SV    + +++ DL 
Sbjct: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802

Query: 396 ADTEYQISVSAMKGMTSSEPISIMEKT 422
           A T+Y++ VSA+     SE +S   +T
Sbjct: 803 AATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score = 37.4 bits (85), Expect = 0.23
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 2/104 (1%)

Query: 319 GVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQH 378
           GV E L  LV+   +  PP  L    V+ + V L W PS    T Y V  +P +    + 
Sbjct: 453 GVGEGLRGLVTTAPL-PPPRALTLAAVTPRTVHLTWQPSAG-ATHYLVRCSPASPKGEEE 510

Query: 379 ALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
              V      + +  L    +Y++SV +++G   SE   I  +T
Sbjct: 511 EREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRART 554



 Score = 37.4 bits (85), Expect = 0.23
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 3/111 (2%)

Query: 13  GAALLLSSIEAEVDP-PSDLNFKIIDENTVHMSW-AKPVDPIVGYRITVDPTTDGPTKEF 70
           G++ L   +  +  P PS L+   +  + V ++W A     ++ Y+IT  P  +G   E 
Sbjct: 634 GSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEI 693

Query: 71  TLSASTTETLLSELVPETEYVVTITS-YDEVEESVPVIGQLTIQTGSSTKP 120
           ++  +    +L  L   TEY VTI + Y +   S PV  + T  T S + P
Sbjct: 694 SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPP 744



 Score = 37.0 bits (84), Expect = 0.30
 Identities = 21/71 (29%), Positives = 31/71 (43%)

Query: 820 LRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQY 879
           LR++      +++ W  + G    YLV   P+AG   QEV +   T    + GL     Y
Sbjct: 32  LRLAVLPEDRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGY 91

Query: 880 ALSVTALYASG 890
            L +  L  SG
Sbjct: 92  TLQIFELTGSG 102



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 27  PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD-GPTKEFTLSASTTETLLSELV 85
           PPS+L       +++ +SW  P+  ++ Y +T  P +  GP K  ++  + +   L +L 
Sbjct: 743 PPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQ 802

Query: 86  PETEYVVTITSYDEV--EESVPVIGQ 109
             T+Y V +++       E+V   GQ
Sbjct: 803 AATKYRVLVSAIYAAGRSEAVSATGQ 828



 Score = 34.3 bits (77), Expect = 1.9
 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 7/121 (5%)

Query: 737 DSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796
           D  ++ W ++ G  L Y +  +P+AG   +EV       + T+  L P   Y + +    
Sbjct: 40  DRLQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFE-- 97

Query: 797 FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGET 856
            +G G  L   A  E V     DL+ S    S+ +   SGAP     +  +  P    E 
Sbjct: 98  LTGSGRFLL--ARREFV---IEDLKSSSLDRSSQRPLGSGAPEPTPSHTGSPDPEQASEP 152

Query: 857 Q 857
           Q
Sbjct: 153 Q 153



 Score = 33.9 bits (76), Expect = 2.5
 Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 23  AEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLL 81
           A + PP  L    +   TVH++W +P      Y +   P +  G  +E  +     E LL
Sbjct: 465 APLPPPRALTLAAVTPRTVHLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLL 523

Query: 82  SELVPETEYVVTITS 96
             L P  +Y V++ S
Sbjct: 524 DGLEPGRDYEVSVQS 538



 Score = 32.7 bits (73), Expect = 5.7
 Identities = 29/127 (22%), Positives = 49/127 (38%), Gaps = 16/127 (12%)

Query: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTE 1919
            L ++W  +EG+   Y +   P AG  E+ V +   T  A +  L P   YT+ +  +   
Sbjct: 42   LQMKWRESEGSGLGYLVQVKPMAGDSEQEVILTTKTPKATVGGLSPSKGYTLQIFELTGS 101

Query: 1920 G-----------DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVY 1968
            G           +  ++S   R+  R L        PTP+       P P    + +V +
Sbjct: 102  GRFLLARREFVIEDLKSSSLDRSSQRPLGSGAP--EPTPSHTG---SPDPEQASEPQVAF 156

Query: 1969 SPVDGTR 1975
            +P    R
Sbjct: 157  TPSQDPR 163


>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score =  387 bits (995), Expect = e-107
 Identities = 380/1540 (24%), Positives = 643/1540 (41%), Gaps = 145/1540 (9%)

Query: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746

Query: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035

Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093

Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136

Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179

Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239

Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT--GYI 1504
              EY V+VY+V +D+ S P+  T       +  L+  D+  +++ ++W P+  +T  GY 
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYR 1299

Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
            ++     +  P    E  +  +V    +T L P  +Y ++V  +++   S P T+ + T 
Sbjct: 1300 ITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357

Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEVDRSETSTSL 1621
             +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +  S+ +  L
Sbjct: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416

Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
             +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F   W    + 
Sbjct: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRAT 1475

Query: 1682 VSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
            ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E ES  LIG 
Sbjct: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-ESPLLIGQ 1534

Query: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800
            + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + G    Q  T
Sbjct: 1535 QSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586

Query: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT--------VRNLRV 1852
            + G +++  +  LKP   YTITV ++      GR      +KP++            ++V
Sbjct: 1587 VPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTEIDKPSQMQV 1641

Query: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTV 1911
             D   ++++V+W  +      Y++   P  G GP +      +     +  LQP   Y  
Sbjct: 1642 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY-- 1699

Query: 1912 TVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGPVLQYRVVYS 1969
             VV VY +   G +    +T +  + R   +   +   +S+ + W+   G V +YRV YS
Sbjct: 1700 -VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1758

Query: 1970 -PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-PAQGRTLPRS 2026
             P DG    E    P G      L+ L P + Y+V++VAL+ D E  P    Q   +P  
Sbjct: 1759 SPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP-- 1814

Query: 2027 GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPL 2085
             P +L+    T  SLS  W   +  +  YR+  +P     P+ E    P   ++V++  L
Sbjct: 1815 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS-SSVVVSGL 1873

Query: 2086 QPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144
               T Y+++V A+ +        G   T+  + PP+   ++D   T   +SW      + 
Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933

Query: 2145 GYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203
            G+++   P     P++  +  ++ SYT+  L P T Y + +Y   D+  S P+    +T 
Sbjct: 1934 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1993

Query: 2204 YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTG 2261
                ++L+      ++  V W P RA  T Y +K   P    R      R   T    TG
Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053

Query: 2262 LSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301
            L P T+Y + V     N +   + +    TV+ T   T P
Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2092



 Score =  297 bits (760), Expect = 1e-79
 Identities = 307/1324 (23%), Positives = 527/1324 (39%), Gaps = 86/1324 (6%)

Query: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917

Query: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977

Query: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035

Query: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148

Query: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPE 1266

Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPA-PGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
                 +L   D T SS  + W P     + GY++T    G+   + E  V        + 
Sbjct: 1267 VPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326

Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205
             L  G  Y ++V  + +GGES+P    + T +   T +   + G + +    A       
Sbjct: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP------ 1380

Query: 1206 GSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQA 1265
               SI   NF    S +    +V ++       A+   +  P TE+ ++      S+ + 
Sbjct: 1381 -PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQ 1435

Query: 1266 VANLPYKGG-----NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320
              + P +G      ++ TG+  + I   +F T   + PRA   G  I             
Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPRE 1494

Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380
             ++      +    +    E  + ++A +  +     +    ++S               
Sbjct: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS--------------- 1539

Query: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETST 1439
                 + P +L +   T  S  +SW  P+ +V  Y++ Y    G    QEF V   +++ 
Sbjct: 1540 -----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594

Query: 1440 VLKDLKPETEYVVNVYSVV----EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ 1495
             +  LKP  +Y + VY+V         S+P+    +T       + + DV   ++ V+W 
Sbjct: 1595 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1654

Query: 1496 PVGG-ATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTS 1554
            P     TGY ++  P     PT+ K    GP   +M +  L P  EY V+V A      S
Sbjct: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712

Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EV 1612
            +P+    VT  + RP+ L   DV   ++ + WE   G+V +Y V Y +PE+ + E+    
Sbjct: 1713 QPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771

Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672
            D  E +  L+ L   + YTVSV A+HD+ ES P+   ++T  +PAPT+LK T+VT     
Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLS 1830

Query: 1673 GTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDE 1731
              W      ++ YR+   P   +  M+ I L  D +++V   L   T YEVS+ A+    
Sbjct: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL---- 1886

Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791
                D + S     ++TT    S PR  +V +AT  ++T+ W   +  +  +++   P+ 
Sbjct: 1887 ---KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1943

Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLR 1851
            G+   Q  TI     S  +  L+P T Y I + +L  +     +     T  ++   NLR
Sbjct: 1944 GQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLR 2001

Query: 1852 VYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYT 1910
                + ++L V W         Y + Y      P E+VP P      A +  L+P T YT
Sbjct: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061

Query: 1911 VTVV 1914
            + V+
Sbjct: 2062 IYVI 2065



 Score =  201 bits (510), Expect = 1e-50
 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%)

Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679

Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738

Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798

Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858

Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912

Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972

Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031

Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089

Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142

Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257

Query: 2106 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 2161
             ++    T+    PQ   +S  D   +   + W P + S ++GY+I     G   P+ E 
Sbjct: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314

Query: 2162 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220
            FV      YT+  L P   YD++V    + G S P T    T     TDL+   IG DT 
Sbjct: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374

Query: 2221 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 2272
             V W+P  +   T++ ++ SP        E+++  S+ +   T L P T+Y V+V
Sbjct: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429



 Score =  201 bits (510), Expect = 1e-50
 Identities = 157/551 (28%), Positives = 237/551 (43%), Gaps = 20/551 (3%)

Query: 635  PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693
            P+DL     T      +W      V  Y ITY E  G+  V     P S ++  +S LKP
Sbjct: 1542 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1601

Query: 694  ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749
               Y + V A    G     S P++    TE  K  P  ++VTD   +S  + W  +   
Sbjct: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1659

Query: 750  VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808
            V  YR+   P  G G ++  T  P+Q   T+E L P  +Y VSV  +  SG   PL   A
Sbjct: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1719

Query: 809  ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYT-PVAGGETQEVTVRGDTTN 867
             T   R  P+ L  +D    ++K++W    G+V +Y VTY+ P  G         G+   
Sbjct: 1720 VTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777

Query: 868  TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927
              LQGL+ G++Y +SV AL+       L G  +T     +P DL    +T TS+ A WT 
Sbjct: 1778 AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTP 1835

Query: 928  APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987
                + GYRV            E NL  D+   ++  L   TKY +SV+A   +    P 
Sbjct: 1836 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1895

Query: 988  TGDATT-ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046
             G  TT E     +  +V + TE T+ ++W+     +  ++V   P      +   + P 
Sbjct: 1896 QGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1955

Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106
            V S  +  LQP T Y I +  +             +TA    +P NL+    T +S  V+
Sbjct: 1956 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA--IDAPSNLRFLATTPNSLLVS 2013

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNT--VVLEELRAGTTYKVNVFGMFDGG 1164
            W+P    + GY + +   G   R  E+V  P        +  L  GT Y + V  + +  
Sbjct: 2014 WQPPRARITGYIIKYEKPGSPPR--EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 2071

Query: 1165 ESSPLVGQEMT 1175
            +S PL+G++ T
Sbjct: 2072 KSEPLIGRKKT 2082



 Score =  193 bits (490), Expect = 3e-48
 Identities = 214/887 (24%), Positives = 369/887 (41%), Gaps = 87/887 (9%)

Query: 334  VEPPSNL-IAMEVSSKYVKLNWNPSPSP-VTGYKVILTPMTAGSRQHALS--VGPQTTTL 389
            + PP+NL +     +  + ++W  S +P +TGY++  TP T G + ++L   V    ++ 
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP-TNGQQGNSLEEVVHADQSSC 1232

Query: 390  SVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSY 449
            +  +LS   EY +SV  +K     E + I +   P   Q+     VDI    + L     
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKD--DKESVPISDTIIPEVPQLTDLSFVDITDSSIGL--RWT 1288

Query: 450  SIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYS---RDPHTEFTLKKFTKVEDIIEA 506
             +  +  +  R  +    +   I  + V  S+  Y+    +P  ++ +   T +      
Sbjct: 1289 PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN----- 1343

Query: 507  INTFPYRGGSTNTGKAMTYVREKIFVPSKGSR--SNVPKVMILITDGKSSDAFRDPAIKL 564
                   GG +    A T + ++  VP       +N+    + +T          P+I L
Sbjct: 1344 -------GGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP------PSIDL 1386

Query: 565  RNSDVEIFAVGVKDAVRSELEAIASPPAE--THVFTVEDFDAFQRISFELTQSICLRIEQ 622
             N  V    V  ++ V +EL    S  A   T++    ++       +E  +S  LR  Q
Sbjct: 1387 TNFLVRYSPVKNEEDV-AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445

Query: 623  ELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEP 680
                  K     P  + FS++T+  F  +W      +  Y I +  +  +G      V P
Sbjct: 1446 ------KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV-P 1498

Query: 681  ASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFK 740
             S  S+ L++L P T Y+V++ A      S  L G+++T  V   PR+L+V   T  S  
Sbjct: 1499 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--VSDVPRDLEVVAATPTSLL 1556

Query: 741  ITWTQAPGRVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799
            I+W      V  YRI Y    G    +E T P ++   T+  L P   Y ++V      G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616

Query: 800  PGT----PLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAG-G 854
                   P++ N  TE  +  P  ++V+D   +++ + W  +   V  Y VT TP  G G
Sbjct: 1617 DSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674

Query: 855  ETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTK 914
             T+  T   D T   ++GL+   +Y +SV A   SG    L     T  +R  P+ L   
Sbjct: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1732

Query: 915  DITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTM------------I 962
            D+   SI   W S  G V  YRV++ S            PED IH +            +
Sbjct: 1733 DVDVDSIKIAWESPQGQVSRYRVTYSS------------PEDGIHELFPAPDGEEDTAEL 1780

Query: 963  ENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGK 1022
            + L+P ++Y +SV A +   E +PL G  +T +   +  LK  + T  ++   W P   +
Sbjct: 1781 QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD-LKFTQVTPTSLSAQWTPPNVQ 1839

Query: 1023 VVNYRVVYRPHGR-GKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSG 1081
            +  YRV   P  + G      + P  +S V+  L   T Y+++V  +      +  QG  
Sbjct: 1840 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1899

Query: 1082 TTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNT 1141
            TT      PR  + +D T ++  ++W      + G++V   P      + +  + P   +
Sbjct: 1900 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRS 1958

Query: 1142 VVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSS 1188
              +  L+ GT YK+ ++ + D   SSP+V    T +   + +  L++
Sbjct: 1959 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLAT 2005



 Score =  176 bits (447), Expect = 2e-43
 Identities = 214/960 (22%), Positives = 374/960 (38%), Gaps = 130/960 (13%)

Query: 297  FNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP 356
            + V   +  +D    +I+ +  G  E     ++ +  V PP++L    +    +++ W P
Sbjct: 1323 YTVTGLEPGIDYDISVITLINGG--ESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 357  SPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP 415
             PS  +T + V  +P+        LS+ P    + + +L   TEY +SVS++     S P
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 416  ISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYSIGIANFVKVRAFLEVLVKSFEIS 473
            +   +KT           G+D    I F  +   S+++   +++  RA     +  + I 
Sbjct: 1441 LRGRQKT-----------GLDSPTGIDFSDITANSFTV---HWIAPRA----TITGYRIR 1482

Query: 474  PNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKI 530
             +    S   +  R PH+    TL   T   + + +I     R  S             +
Sbjct: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES------------PL 1530

Query: 531  FVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR-----------NSDVEIFAVGVK 577
             +  + + S+VP+ + ++    +S   ++  PA+ +R           NS V+ F V   
Sbjct: 1531 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV--- 1587

Query: 578  DAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD 637
               +S        P   +  TV      +  S   ++ I +    E+          P  
Sbjct: 1588 PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSKPISINYRTEID--------KPSQ 1638

Query: 638  LSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEPASSTSVVLSSLKPET 695
            +  ++V        W P+   V  Y +T   K   G  +     P   T + +  L+P  
Sbjct: 1639 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTV 1697

Query: 696  LYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRI 755
             Y+V+V A+   G S PL     T   +  P+ L  TD   DS KI W    G+V RYR+
Sbjct: 1698 EYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRV 1755

Query: 756  IYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814
             Y     G       P  +     L+ L P ++Y VSV+  +      PL G  +T    
Sbjct: 1756 TYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--AI 1813

Query: 815  GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP-VAGGETQEVTVRGDTTNTVLQGL 873
              P DL+ +  T +++   W+    ++  Y V  TP    G  +E+ +  D+++ V+ GL
Sbjct: 1814 PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGL 1873

Query: 874  KEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVR 933
               T+Y +SV AL  +       G  TTLE    P+     D T+T+I   W +    + 
Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933

Query: 934  GYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993
            G++V            ++ +  D     I  LQP T Y+I ++    +    P+  DA+T
Sbjct: 1934 GFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992

Query: 994  ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPTVTSTVL 1052
             +   S  L+    T N++ V+W+P   ++  Y + Y +P    +++V +  P VT   +
Sbjct: 1993 AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051

Query: 1053 KRLQPQTTYDITVL--------------------------PIYKMGEG-KLRQGSGTTAS 1085
              L+P T Y I V+                          P Y  G G +L   SG   S
Sbjct: 2052 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2111

Query: 1086 -----RFKSPRNLKTSDPT--------------------MSSFRVTWEPAPGEVKGYKVT 1120
                  F+     +T+ PT                    +S   ++W P   +   Y ++
Sbjct: 2112 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIIS 2170

Query: 1121 FHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDT 1180
             HP G D    +  V     +  L  L  G TY + V  + D  +    V +E+ T+ ++
Sbjct: 2171 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--QQRHKVREEVVTVGNS 2228



 Score =  161 bits (407), Expect = 1e-38
 Identities = 149/568 (26%), Positives = 249/568 (43%), Gaps = 27/568 (4%)

Query: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786

Query: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844

Query: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904

Query: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963

Query: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079

Query: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136

Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195

Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255

Query: 1166 SSPL---VGQEMTTLSDTTVMPILSSGM 1190
            S P+   +  E+  L+D + + I  S +
Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSI 1283



 Score =  160 bits (405), Expect = 2e-38
 Identities = 151/584 (25%), Positives = 255/584 (43%), Gaps = 28/584 (4%)

Query: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944

Query: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002

Query: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062

Query: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119

Query: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176

Query: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232

Query: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPA- 1019
              +NL P  +Y +SV+      E  P++     E+ Q +    VD  T++++ + W P  
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD-ITDSSIGLRWTPLN 1291

Query: 1020 PGKVVNYRVVYRPHGRGKQMVAK-VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQ 1078
               ++ YR+     G G  +    V  +V    +  L+P   YDI+V+ +   GE     
Sbjct: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351

Query: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGP 1137
             +  TA     P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P
Sbjct: 1352 LTQQTA--VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409

Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
             DN VVL  L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1453



 Score =  159 bits (403), Expect = 3e-38
 Identities = 201/869 (23%), Positives = 340/869 (39%), Gaps = 73/869 (8%)

Query: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963

Query: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104

Query: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164

Query: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
              A  +S    +L P   Y V+V    +D  S+P++  +T         +L   D T  S
Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSS 1282

Query: 739  FKITWTQA-PGRVLRYRIIYRPVAGGES---REVTTPPNQRRRTLENLIPDTKYEVSVIP 794
              + WT      ++ YRI    VA GE     E     +    T+  L P   Y++SVI 
Sbjct: 1283 IGLRWTPLNSSTIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1340

Query: 795  EYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPG-KVKQYLVTYTPVAG 853
                G   P T     +     P DLR ++    TM+++W+  P   +  +LV Y+PV  
Sbjct: 1341 LINGGESAPTT--LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398

Query: 854  GE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             E   E+++       VL  L  GT+Y +SV+++Y       L G   T     SP  + 
Sbjct: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGID 1456

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR 972
              DIT  S   +W +    + GYR+     +      E  +P       + NL P T+Y 
Sbjct: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516

Query: 973  ISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRP 1032
            +S+ A     E   L G  +T +S   + L+V   T  ++ ++W      V  YR+ Y  
Sbjct: 1517 VSIVALNGREESPLLIGQQST-VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575

Query: 1033 HGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGE--GKLRQGSGTTASRFK 1088
             G G   V +  VP + ++  +  L+P   Y ITV  +   G+     +  S    +   
Sbjct: 1576 TG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634

Query: 1089 SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELR 1148
             P  ++ +D   +S  V W P+   V GY+VT  P            GP    + +E L+
Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694

Query: 1149 AGTTYKVNVFGMFDGGESSPLVGQEMTTL 1177
                Y V+V+     GES PLV   +T +
Sbjct: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI 1723



 Score =  105 bits (263), Expect = 5e-22
 Identities = 119/490 (24%), Positives = 188/490 (38%), Gaps = 49/490 (10%)

Query: 622  QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679
            Q L   +  A   P DL F++VT       W+P    +  Y   +T KE  G  +   + 
Sbjct: 1803 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1862

Query: 680  PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739
            P SS SVV+S L   T Y V+V A  +   S P  G  TT E    PR  +VTD T  + 
Sbjct: 1863 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1921

Query: 740  KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799
             I+W      +  +++   P  G    + T  P+ R  T+  L P T Y++ +     + 
Sbjct: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981

Query: 800  PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859
              +P+  +A+T      P +LR    T +++ +SW     ++  Y++ Y    G   +EV
Sbjct: 1982 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 2038

Query: 860  T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917
                R   T   + GL+ GT+Y + V AL  +   + L G   T+++       VT    
Sbjct: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQK----TPFVTHPGY 2094

Query: 918  DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977
            DT  G       G                  G++ + E+  H       P T       A
Sbjct: 2095 DTGNGIQLPGTSG-------------QQPSVGQQMIFEE--HGFRRTTPPTT-------A 2132

Query: 978  TYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGK 1037
            T       P   +             V +E  +   ++W P       Y +   P G  +
Sbjct: 2133 TPIRHRPRPYPPN-------------VGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDE 2178

Query: 1038 Q-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTS 1096
            + +  +VP T TS  L  L    TY+I V  +      K+R+   T  +      N  T 
Sbjct: 2179 EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTD 2238

Query: 1097 DPTMSSFRVT 1106
            D     + V+
Sbjct: 2239 DSCFDPYTVS 2248



 Score = 66.6 bits (161), Expect = 4e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859

Query: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916

Query: 134 SVS 136
            V+
Sbjct: 917 EVT 919



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%)

Query: 2011 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 2064
            GE +  P Q  T P S GP  + VF   T    NS  + W+      + +Y + + P   
Sbjct: 595  GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650

Query: 2065 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 2106
                +  T+PG  N+  ++ L+P   Y+  +I++ + G                      
Sbjct: 651  VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710

Query: 2107 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 2164
            +TG       L   +  +++   + F VSW  +   V G+++ Y+    G          
Sbjct: 711  VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770

Query: 2165 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 2223
              TS  + +L P   Y VNVY   + G  S+ L+   TT      D    Q+   +  V+
Sbjct: 771  TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830

Query: 2224 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 2282
            WS P    T YR+  SP+      E+ +  +  S   + L P   Y +T++    N E  
Sbjct: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890

Query: 2283 GVSVKEHTTVKPTEAPTEPP 2302
             V +++ TT  P       P
Sbjct: 891  PVVIQQETTGTPRSDTVPSP 910



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691

Query: 83   ELVPETEYVVTITSYDEVEESVPVI 107
             L P  EYVV++ + +   ES P++
Sbjct: 1692 GLQPTVEYVVSVYAQNPSGESQPLV 1716



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 2/90 (2%)

Query: 22   EAEVDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTET 79
            +  V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    
Sbjct: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414

Query: 80   LLSELVPETEYVVTITSYDEVEESVPVIGQ 109
            +L+ L+P TEYVV+++S  E  ES P+ G+
Sbjct: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 1509 LTPGTEYVVSIVALNGREESPLLIGQ 1534



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
            L+ +    +D P  L F  +D +++ ++W  P   +  YR+T     DG  + F      
Sbjct: 1715 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1774

Query: 77   TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135
             +T  L  L P +EY V++ +  +  ES P+IG     T S+  P       T++   S+
Sbjct: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1829

Query: 136  SA-WT 139
            SA WT
Sbjct: 1830 SAQWT 1834



 Score = 48.9 bits (115), Expect = 8e-05
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 1805 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864

Query: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849

Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223

Query: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 1530 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589

Query: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 1590 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1633

Query: 131  QKCSVSAWTDL 141
             K S    TD+
Sbjct: 1634 DKPSQMQVTDV 1644



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 9/102 (8%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP 125
            L P TEY + + +    ++S P+IG+         K V+K P
Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPLIGR--------KKTVQKTP 2087



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 1886 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1944

Query: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 1945 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797

Query: 102 ESVPVIGQLTIQTGSSTKP 120
           E       L + T  +T P
Sbjct: 798 EQ-----SLILSTSQTTAP 811


>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
          Length = 2477

 Score =  386 bits (991), Expect = e-106
 Identities = 377/1533 (24%), Positives = 640/1533 (41%), Gaps = 144/1533 (9%)

Query: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746

Query: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035

Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093

Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136

Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179

Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239

Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT--GYI 1504
              EY V+VY+V +D+ S P+  T       +  L+  D+  +++ ++W P+  +T  GY 
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYR 1299

Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
            ++     +  P    E  +  +V    +T L P  +Y ++V  +++   S P T+ + T 
Sbjct: 1300 ITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357

Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEVDRSETSTSL 1621
             +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +  S+ +  L
Sbjct: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416

Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
             +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F   W    + 
Sbjct: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRAT 1475

Query: 1682 VSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
            ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E ES  LIG 
Sbjct: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-ESPLLIGQ 1534

Query: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800
            + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + G    Q  T
Sbjct: 1535 QSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586

Query: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT--------VRNLRV 1852
            + G +++  +  LKP   YTITV ++      GR      +KP++            ++V
Sbjct: 1587 VPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTEIDKPSQMQV 1641

Query: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTV 1911
             D   ++++V+W  +      Y++   P  G GP +      +     +  LQP   Y  
Sbjct: 1642 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY-- 1699

Query: 1912 TVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGPVLQYRVVYS 1969
             VV VY +   G +    +T +  + R   +   +   +S+ + W+   G V +YRV YS
Sbjct: 1700 -VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1758

Query: 1970 -PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-PAQGRTLPRS 2026
             P DG    E    P G      L+ L P + Y+V++VAL+ D E  P    Q   +P  
Sbjct: 1759 SPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP-- 1814

Query: 2027 GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPL 2085
             P +L+    T  SLS  W   +  +  YR+  +P     P+ E    P   ++V++  L
Sbjct: 1815 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS-SSVVVSGL 1873

Query: 2086 QPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144
               T Y+++V A+ +        G   T+  + PP+   ++D   T   +SW      + 
Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933

Query: 2145 GYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203
            G+++   P     P++  +  ++ SYT+  L P T Y + +Y   D+  S P+    +T 
Sbjct: 1934 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1993

Query: 2204 YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTG 2261
                ++L+      ++  V W P RA  T Y +K   P    R      R   T    TG
Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053

Query: 2262 LSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
            L P T+Y + V     N +   +  ++ T   P
Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086



 Score =  297 bits (760), Expect = 1e-79
 Identities = 307/1324 (23%), Positives = 527/1324 (39%), Gaps = 86/1324 (6%)

Query: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917

Query: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977

Query: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035

Query: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148

Query: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPE 1266

Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPA-PGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
                 +L   D T SS  + W P     + GY++T    G+   + E  V        + 
Sbjct: 1267 VPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326

Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205
             L  G  Y ++V  + +GGES+P    + T +   T +   + G + +    A       
Sbjct: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP------ 1380

Query: 1206 GSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQA 1265
               SI   NF    S +    +V ++       A+   +  P TE+ ++      S+ + 
Sbjct: 1381 -PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQ 1435

Query: 1266 VANLPYKGG-----NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320
              + P +G      ++ TG+  + I   +F T   + PRA   G  I             
Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPRE 1494

Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380
             ++      +    +    E  + ++A +  +     +    ++S               
Sbjct: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS--------------- 1539

Query: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETST 1439
                 + P +L +   T  S  +SW  P+ +V  Y++ Y    G    QEF V   +++ 
Sbjct: 1540 -----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594

Query: 1440 VLKDLKPETEYVVNVYSVV----EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ 1495
             +  LKP  +Y + VY+V         S+P+    +T       + + DV   ++ V+W 
Sbjct: 1595 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1654

Query: 1496 PVGG-ATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTS 1554
            P     TGY ++  P     PT+ K    GP   +M +  L P  EY V+V A      S
Sbjct: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712

Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EV 1612
            +P+    VT  + RP+ L   DV   ++ + WE   G+V +Y V Y +PE+ + E+    
Sbjct: 1713 QPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771

Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672
            D  E +  L+ L   + YTVSV A+HD+ ES P+   ++T  +PAPT+LK T+VT     
Sbjct: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLS 1830

Query: 1673 GTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDE 1731
              W      ++ YR+   P   +  M+ I L  D +++V   L   T YEVS+ A+    
Sbjct: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL---- 1886

Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791
                D + S     ++TT    S PR  +V +AT  ++T+ W   +  +  +++   P+ 
Sbjct: 1887 ---KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1943

Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLR 1851
            G+   Q  TI     S  +  L+P T Y I + +L  +     +     T  ++   NLR
Sbjct: 1944 GQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLR 2001

Query: 1852 VYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYT 1910
                + ++L V W         Y + Y      P E+VP P      A +  L+P T YT
Sbjct: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061

Query: 1911 VTVV 1914
            + V+
Sbjct: 2062 IYVI 2065



 Score =  261 bits (667), Expect = 7e-69
 Identities = 250/933 (26%), Positives = 398/933 (42%), Gaps = 51/933 (5%)

Query: 1393 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 1451
            ++E T  SF VSW   SD+V  ++VEY     G + Q   +    TS  + DL P  +Y+
Sbjct: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787

Query: 1452 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 1509
            VNVY + ED E S  L  ++ T P       +  V  T++ V+W +P    TGY + Y P
Sbjct: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847

Query: 1510 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 1568
              +   T   E+ L  T N + L+DL P  +Y +T+ AV  +  S PV +++ T   PR 
Sbjct: 848  SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904

Query: 1569 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 1620
                 P+DL+  +VT   + + W P    V  Y   ++    P E  + + + R+ T   
Sbjct: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963

Query: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680
            +  L     Y   V AV    ES P+TAQ+TT+ + APTNL+    T       W    +
Sbjct: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022

Query: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
             ++ YR+T          +  +    +     NL P + Y VS+ AI  ++        S
Sbjct: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075

Query: 1741 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 1798
             +   + TT  P S   P N +V   T  ++ + W PA  R+  +++  +PS  +G E  
Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128

Query: 1799 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 1857
              +     S+V+  L P   Y  T+  L    E           PL+   NL +  +P T
Sbjct: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188

Query: 1858 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 1914
              L V W+ +   +   Y++   P  G  G      +  + +     NL P   Y V+V 
Sbjct: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248

Query: 1915 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPA-PGPVLQYRVVYSPVDG 1973
             V  + +    SDT    +  L  ++   + T +S+ +RW P     ++ YR+       
Sbjct: 1249 TVKDDKESVPISDTIIPEVPQLT-DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGE 1307

Query: 1974 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 2033
              P     V  +     +  L P   Y ++++ L + GE  P+    +T     P +LR 
Sbjct: 1308 GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-PPPTDLRF 1366

Query: 2034 FGETTNSLSVAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 2092
                 +++ V W       +  + + YSP   +      ++    N V+L  L P T Y 
Sbjct: 1367 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426

Query: 2093 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 2152
            ++V +VYE  +   L G  +T GL  P  I  SD     F V W    + + GY+I + P
Sbjct: 1427 VSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1485

Query: 2153 VG-SNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL 2210
               S  P E  V     S TL NL P T Y V++ A      S  L  Q +T+     DL
Sbjct: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545

Query: 2211 KTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDY 2268
            +       +  + W +P      YR+      G    QE TV GS+++   +GL P  DY
Sbjct: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605

Query: 2269 GVTVFVQTPNLEGPG----VSVKEHTTV-KPTE 2296
             +TV+  T   + P     +S+   T + KP++
Sbjct: 1606 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638



 Score =  225 bits (573), Expect = 6e-58
 Identities = 250/1005 (24%), Positives = 410/1005 (40%), Gaps = 90/1005 (8%)

Query: 628  KKKAYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTS 685
            ++ A  PP DL F+ +     +  W+P    ++ ++ + Y     +++V  +  + S  +
Sbjct: 1354 QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1413

Query: 686  VVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQ 745
            VVL++L P T Y+V+V++ YE   S PL G + T     +P  +  +D T +SF + W  
Sbjct: 1414 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIA 1471

Query: 746  APGRVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL 804
                +  YRI + P    G  RE   P ++   TL NL P T+Y VS++          L
Sbjct: 1472 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1531

Query: 805  TGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRG 863
             G  +T  V   PRDL V   T +++ +SW      V+ Y +TY    G    QE TV G
Sbjct: 1532 IGQQST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589

Query: 864  DTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDT 919
              +   + GLK G  Y ++V A+  +G GD+             E   P  +   D+ D 
Sbjct: 1590 SKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDN 1647

Query: 920  SIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATY 979
            SI   W  +   V GYRV+         T  K    D     IE LQP  +Y +SV+A  
Sbjct: 1648 SISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707

Query: 980  SSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQM 1039
             SGE +PL   A T + +  K L   +   +++++ W+   G+V  YRV Y     G   
Sbjct: 1708 PSGESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1766

Query: 1040 VAKVPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDP 1098
            +   P     T  L+ L+P + Y ++V+ ++   E +   G+ +TA    +P +LK +  
Sbjct: 1767 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQV 1824

Query: 1099 TMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVF 1158
            T +S    W P   ++ GY+V   P      + E+ + P  ++VV+  L   T Y+V+V+
Sbjct: 1825 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1884

Query: 1159 GMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205
             + D   S P  G               +T  ++TT+     +  E +T  + D V   +
Sbjct: 1885 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PAN 1943

Query: 1206 GSWSIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQ 1264
            G   I R     VRS+ I+ +    D   K     L   +         +   D  S L+
Sbjct: 1944 GQTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDAPSNLR 2001

Query: 1265 AVANLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVE 1317
             +A  P             +TG  + + +  +   +   RPR       IT  +   +  
Sbjct: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061

Query: 1318 APSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT---IN 1374
                 LK+       IG K  DE+  +++     + H   + D  S  +    +T    +
Sbjct: 2062 IYVIALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYD 2120

Query: 1375 LCNSVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEF 1430
              N ++ PG   + PS    ++  E     FR +  P + +  R++   YP + G  +E 
Sbjct: 2121 TGNGIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYPPNVG--EEI 2175

Query: 1431 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 1490
             +  +    V   L P    +    S  ++  S+                       TT 
Sbjct: 2176 QIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQ-----------------------TT- 2211

Query: 1491 HVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV-- 1548
             + W P    + YI+S  PV   E   P + R+  T     LT L     Y + V+A+  
Sbjct: 2212 -ISWAPFQDTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 2268

Query: 1549 --LHDLTSEPVTV-REVTLPLPRPQDLKLRD---VTHSTMNVFWE 1587
               H +  E VTV   V   L +P D    D   V+H  +   WE
Sbjct: 2269 QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2313



 Score =  201 bits (510), Expect = 1e-50
 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%)

Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679

Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738

Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798

Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858

Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912

Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972

Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031

Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089

Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142

Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257

Query: 2106 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 2161
             ++    T+    PQ   +S  D   +   + W P + S ++GY+I     G   P+ E 
Sbjct: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314

Query: 2162 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220
            FV      YT+  L P   YD++V    + G S P T    T     TDL+   IG DT 
Sbjct: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374

Query: 2221 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 2272
             V W+P  +   T++ ++ SP        E+++  S+ +   T L P T+Y V+V
Sbjct: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429



 Score =  173 bits (439), Expect = 2e-42
 Identities = 183/796 (22%), Positives = 324/796 (40%), Gaps = 75/796 (9%)

Query: 297  FNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP 356
            + V   +  +D    +I+ +  G  E     ++ +  V PP++L    +    +++ W P
Sbjct: 1323 YTVTGLEPGIDYDISVITLINGG--ESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 357  SPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP 415
             PS  +T + V  +P+        LS+ P    + + +L   TEY +SVS++     S P
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 416  ISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYSIGIANFVKVRAFLEVLVKSFEIS 473
            +   +KT           G+D    I F  +   S+++   +++  RA     +  + I 
Sbjct: 1441 LRGRQKT-----------GLDSPTGIDFSDITANSFTV---HWIAPRA----TITGYRIR 1482

Query: 474  PNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKI 530
             +    S   +  R PH+    TL   T   + + +I     R  S             +
Sbjct: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES------------PL 1530

Query: 531  FVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR-----------NSDVEIFAVGVK 577
             +  + + S+VP+ + ++    +S   ++  PA+ +R           NS V+ F V   
Sbjct: 1531 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV--- 1587

Query: 578  DAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD 637
               +S        P   +  TV      +  S   ++ I +    E+          P  
Sbjct: 1588 PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSKPISINYRTEID--------KPSQ 1638

Query: 638  LSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEPASSTSVVLSSLKPET 695
            +  ++V        W P+   V  Y +T   K   G  +     P   T + +  L+P  
Sbjct: 1639 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTV 1697

Query: 696  LYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRI 755
             Y+V+V A+   G S PL     T   +  P+ L  TD   DS KI W    G+V RYR+
Sbjct: 1698 EYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRV 1755

Query: 756  IYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814
             Y     G       P  +     L+ L P ++Y VSV+  +      PL G  +T    
Sbjct: 1756 TYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--AI 1813

Query: 815  GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP-VAGGETQEVTVRGDTTNTVLQGL 873
              P DL+ +  T +++   W+    ++  Y V  TP    G  +E+ +  D+++ V+ GL
Sbjct: 1814 PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGL 1873

Query: 874  KEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVR 933
               T+Y +SV AL  +       G  TTLE    P+     D T+T+I   W +    + 
Sbjct: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933

Query: 934  GYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993
            G++V            ++ +  D     I  LQP T Y+I ++    +    P+  DA+T
Sbjct: 1934 GFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992

Query: 994  ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPTVTSTVL 1052
             +   S  L+    T N++ V+W+P   ++  Y + Y +P    +++V +  P VT   +
Sbjct: 1993 AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051

Query: 1053 KRLQPQTTYDITVLPI 1068
              L+P T Y I V+ +
Sbjct: 2052 TGLEPGTEYTIYVIAL 2067



 Score =  161 bits (407), Expect = 1e-38
 Identities = 149/568 (26%), Positives = 249/568 (43%), Gaps = 27/568 (4%)

Query: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786

Query: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844

Query: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904

Query: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963

Query: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079

Query: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136

Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195

Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255

Query: 1166 SSPL---VGQEMTTLSDTTVMPILSSGM 1190
            S P+   +  E+  L+D + + I  S +
Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSI 1283



 Score =  160 bits (405), Expect = 2e-38
 Identities = 151/584 (25%), Positives = 255/584 (43%), Gaps = 28/584 (4%)

Query: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944

Query: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002

Query: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062

Query: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119

Query: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176

Query: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232

Query: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPA- 1019
              +NL P  +Y +SV+      E  P++     E+ Q +    VD  T++++ + W P  
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD-ITDSSIGLRWTPLN 1291

Query: 1020 PGKVVNYRVVYRPHGRGKQMVAK-VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQ 1078
               ++ YR+     G G  +    V  +V    +  L+P   YDI+V+ +   GE     
Sbjct: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351

Query: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGP 1137
             +  TA     P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P
Sbjct: 1352 LTQQTA--VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409

Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
             DN VVL  L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1453



 Score =  159 bits (403), Expect = 3e-38
 Identities = 201/869 (23%), Positives = 340/869 (39%), Gaps = 73/869 (8%)

Query: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963

Query: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104

Query: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164

Query: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
              A  +S    +L P   Y V+V    +D  S+P++  +T         +L   D T  S
Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSS 1282

Query: 739  FKITWTQA-PGRVLRYRIIYRPVAGGES---REVTTPPNQRRRTLENLIPDTKYEVSVIP 794
              + WT      ++ YRI    VA GE     E     +    T+  L P   Y++SVI 
Sbjct: 1283 IGLRWTPLNSSTIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1340

Query: 795  EYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPG-KVKQYLVTYTPVAG 853
                G   P T     +     P DLR ++    TM+++W+  P   +  +LV Y+PV  
Sbjct: 1341 LINGGESAPTT--LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398

Query: 854  GE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             E   E+++       VL  L  GT+Y +SV+++Y       L G   T     SP  + 
Sbjct: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGID 1456

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR 972
              DIT  S   +W +    + GYR+     +      E  +P       + NL P T+Y 
Sbjct: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516

Query: 973  ISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRP 1032
            +S+ A     E   L G  +T +S   + L+V   T  ++ ++W      V  YR+ Y  
Sbjct: 1517 VSIVALNGREESPLLIGQQST-VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575

Query: 1033 HGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGE--GKLRQGSGTTASRFK 1088
             G G   V +  VP + ++  +  L+P   Y ITV  +   G+     +  S    +   
Sbjct: 1576 TG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634

Query: 1089 SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELR 1148
             P  ++ +D   +S  V W P+   V GY+VT  P            GP    + +E L+
Sbjct: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694

Query: 1149 AGTTYKVNVFGMFDGGESSPLVGQEMTTL 1177
                Y V+V+     GES PLV   +T +
Sbjct: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI 1723



 Score =  104 bits (259), Expect = 2e-21
 Identities = 135/566 (23%), Positives = 212/566 (37%), Gaps = 91/566 (16%)

Query: 622  QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679
            Q L   +  A   P DL F++VT       W+P    +  Y   +T KE  G  +   + 
Sbjct: 1803 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1862

Query: 680  PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739
            P SS SVV+S L   T Y V+V A  +   S P  G  TT E    PR  +VTD T  + 
Sbjct: 1863 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1921

Query: 740  KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799
             I+W      +  +++   P  G    + T  P+ R  T+  L P T Y++ +     + 
Sbjct: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981

Query: 800  PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859
              +P+  +A+T      P +LR    T +++ +SW     ++  Y++ Y    G   +EV
Sbjct: 1982 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 2038

Query: 860  T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917
                R   T   + GL+ GT+Y + V AL  +   + L G   T E    PQ LVT    
Sbjct: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE---LPQ-LVT---- 2090

Query: 918  DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977
                                               LP   +H   E L   +  + + F 
Sbjct: 2091 -----------------------------------LPHPNLHGP-EILDVPSTVQKTPFV 2114

Query: 978  T---YSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHG 1034
            T   Y +G G  L G +  + S   + +      E+  R T  P     + +R   RP+ 
Sbjct: 2115 THPGYDTGNGIQLPGTSGQQPSVGQQMI----FEEHGFRRTTPPTTATPIRHRP--RPY- 2167

Query: 1035 RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK 1094
                     PP V   +     P+   D  + P           G G          N  
Sbjct: 2168 ---------PPNVGEEIQIGHIPREDVDYHLYP----------HGPGLNP-------NAS 2201

Query: 1095 TSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYK 1154
            T    +S   ++W P   +   Y ++ HP G D    +  V     +  L  L  G TY 
Sbjct: 2202 TGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYN 2260

Query: 1155 VNVFGMFDGGESSPLVGQEMTTLSDT 1180
            + V  + D  +    V +E+ T+ ++
Sbjct: 2261 IIVEALKD--QQRHKVREEVVTVGNS 2284



 Score = 85.9 bits (211), Expect = 6e-16
 Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 61/497 (12%)

Query: 334  VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
            ++ PS +   +V    + + W PS SPVTGY+V  TP          + GP  T +++  
Sbjct: 1633 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1692

Query: 394  LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGV---DIKADIVFLVDGSYS 450
            L    EY +SV A      S+P+      Q     ++  +G+   D+  D + +   S  
Sbjct: 1693 LQPTVEYVVSVYAQNPSGESQPL-----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ 1747

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              ++ +    +  E  +     +P+  + +       P +E+T+      +D    + + 
Sbjct: 1748 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD----MESQ 1803

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK------VMILITDGKSSDAFRDPAIKL 564
            P  G  +    A T ++     P+  S    P         + +T  + +   ++  I L
Sbjct: 1804 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE--INL 1861

Query: 565  RNSDVEIFAVGVKDAVRSEL------EAIASPPAETHVFTVEDFDAFQRISFELTQSICL 618
                  +   G+  A + E+      + + S PA+  V T+E+                 
Sbjct: 1862 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS--------------- 1906

Query: 619  RIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
                           PP+    ++ T      +W    E +  + +    A G   +   
Sbjct: 1907 ---------------PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1951

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
                  S  ++ L+P T Y + +    ++  S P+  + +T     AP NL+    T +S
Sbjct: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST--AIDAPSNLRFLATTPNS 2009

Query: 739  FKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQ--RRRTLENLIPDTKYEVSVIPEY 796
              ++W     R+  Y I Y    G   REV   P       T+  L P T+Y + VI   
Sbjct: 2010 LLVSWQPPRARITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK 2068

Query: 797  FSGPGTPLTGNAATEEV 813
             +    PL G   T+E+
Sbjct: 2069 NNQKSEPLIGRKKTDEL 2085



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 87/374 (23%), Positives = 149/374 (39%), Gaps = 54/374 (14%)

Query: 1384 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 1443
            ++  P    +++ T  +  +SW   ++++  ++V+  P +G    +  +     S  +  
Sbjct: 1904 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963

Query: 1444 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 1502
            L+P T+Y + +Y++ ++  S P+     T      +L      P ++ V WQP     TG
Sbjct: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 2023

Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 1561
            YI+ Y+  K   P R    R  P V +  +T L P TEY + V A+ ++  SEP+  R+ 
Sbjct: 2024 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 2081

Query: 1562 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 1614
                   VTLP P     ++ DV  +     +   PG        Y T    ++      
Sbjct: 2082 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2132

Query: 1615 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTN----LKITEVTSE 1669
             + S   + +F +  +            +PP TA     RP P P N    ++I  +  E
Sbjct: 2133 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183

Query: 1670 -----------GFRGTWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFEN 1713
                       G       G   +S   I+WAPF   D  E I++      DE  L F  
Sbjct: 2184 DVDYHLYPHGPGLNPNASTGQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR- 2240

Query: 1714 LNPNTIYEVSITAI 1727
              P T    ++T +
Sbjct: 2241 -VPGTSTSATLTGL 2253



 Score = 66.6 bits (161), Expect = 4e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859

Query: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916

Query: 134 SVS 136
            V+
Sbjct: 917 EVT 919



 Score = 65.9 bits (159), Expect = 6e-10
 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%)

Query: 2011 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 2064
            GE +  P Q  T P S GP  + VF   T    NS  + W+      + +Y + + P   
Sbjct: 595  GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650

Query: 2065 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 2106
                +  T+PG  N+  ++ L+P   Y+  +I++ + G                      
Sbjct: 651  VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710

Query: 2107 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 2164
            +TG       L   +  +++   + F VSW  +   V G+++ Y+    G          
Sbjct: 711  VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770

Query: 2165 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 2223
              TS  + +L P   Y VNVY   + G  S+ L+   TT      D    Q+   +  V+
Sbjct: 771  TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830

Query: 2224 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 2282
            WS P    T YR+  SP+      E+ +  +  S   + L P   Y +T++    N E  
Sbjct: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890

Query: 2283 GVSVKEHTTVKPTEAPTEPP 2302
             V +++ TT  P       P
Sbjct: 891  PVVIQQETTGTPRSDTVPSP 910



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691

Query: 83   ELVPETEYVVTITSYDEVEESVPVI 107
             L P  EYVV++ + +   ES P++
Sbjct: 1692 GLQPTVEYVVSVYAQNPSGESQPLV 1716



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 2/90 (2%)

Query: 22   EAEVDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTET 79
            +  V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    
Sbjct: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414

Query: 80   LLSELVPETEYVVTITSYDEVEESVPVIGQ 109
            +L+ L+P TEYVV+++S  E  ES P+ G+
Sbjct: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 1509 LTPGTEYVVSIVALNGREESPLLIGQ 1534



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
            L+ +    +D P  L F  +D +++ ++W  P   +  YR+T     DG  + F      
Sbjct: 1715 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1774

Query: 77   TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135
             +T  L  L P +EY V++ +  +  ES P+IG     T S+  P       T++   S+
Sbjct: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1829

Query: 136  SA-WT 139
            SA WT
Sbjct: 1830 SAQWT 1834



 Score = 48.9 bits (115), Expect = 8e-05
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 1805 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864

Query: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849

Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223

Query: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 25/99 (25%), Positives = 45/99 (45%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            ++     ++ PSNL  +  +   + ++W P  + +TGY +      +  R+      P  
Sbjct: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 2046

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425
            T  ++  L   TEY I V A+K    SEP+   +KT  +
Sbjct: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 2085



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 1530 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589

Query: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 1590 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1633

Query: 131  QKCSVSAWTDL 141
             K S    TD+
Sbjct: 1634 DKPSQMQVTDV 1644



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEY + + +    ++S P+IG+
Sbjct: 2054 LEPGTEYTIYVIALKNNQKSEPLIGR 2079



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 1886 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1944

Query: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 1945 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797

Query: 102 ESVPVIGQLTIQTGSSTKP 120
           E       L + T  +T P
Sbjct: 798 EQ-----SLILSTSQTTAP 811


>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score =  383 bits (984), Expect = e-105
 Identities = 357/1428 (25%), Positives = 594/1428 (41%), Gaps = 119/1428 (8%)

Query: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746

Query: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035

Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093

Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136

Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179

Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239

Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504
              EY V+VY+V +D+ S P+  T      P   L   ++GP TM V W P      T ++
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299

Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
            + Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V     S P+  R+ T 
Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356

Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621
             L  P  +   D+T ++  V W      +  Y +R+  PE      +E  V  S  S +L
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415

Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
             +L   T Y VS+ A++   ESP +  Q++T     P +L++   T      +WD  A  
Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474

Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
            V  YRIT+   G +S   E  + G ++T     L P   Y +++ A+    +   D   S
Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530

Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
             + + I   T+  K  P  +QV +   NS++VKW P+S  V  YR+T  P  G G  +T 
Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588

Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859
            T G  Q  + ++ L+P   Y ++V +  P GE   +     T  ++  + L   D    +
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDS 1647

Query: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVVPVYT 1918
            + + W+  +G   +Y++ Y+    G  EL P P G  + A L+ L+P + YTV+VV ++ 
Sbjct: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707

Query: 1919 EGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSE 1978
            + +      T  T +     +++    TP SL  +W P    +  YRV  +P + T P +
Sbjct: 1708 DMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766

Query: 1979 SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGET 2037
             I +  ++  V +  L+  T Y V++ AL       P+     TL   S PR  RV   T
Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826

Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097
              +++++W      +  +++   P  G    + T  P  R+  I   LQP T YKI +  
Sbjct: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI-TGLQPGTDYKIYLYT 1885

Query: 2098 VYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS-- 2155
            + ++     +  +  T  +  P N+           VSW P  + + GY I Y+  GS  
Sbjct: 1886 LNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1944

Query: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203
             E +      +T  T+  L P T Y + V A  ++  S PL  +  T+
Sbjct: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992



 Score =  334 bits (856), Expect = 9e-91
 Identities = 325/1304 (24%), Positives = 551/1304 (42%), Gaps = 84/1304 (6%)

Query: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786

Query: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844

Query: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904

Query: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963

Query: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079

Query: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136

Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195

Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255

Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225
            S P+    +  +   T +   + G + +    A          SI   NF    S +   
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308

Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280
             +V ++       A+   +  P TE+ ++      S+ +   + P +G      ++ TG+
Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364

Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340
              + I   +F T   + PRA   G  I              ++      +    +    E
Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423

Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400
              + ++A +  +     +    ++S                    + P +L +   T  S
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463

Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458
              +SW  P+ +V  Y++ Y    G    QEF V   +++  +  LKP  +Y + VY+V  
Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523

Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514
                   S+P+    +T       + + DV   ++ V+W P     TGY ++  P     
Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583

Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
            PT+ K    GP   +M +  L P  EY V+V A      S+P+    VT  + RP+ L  
Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAF 1640

Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EVDRSETSTSLKDLFSQTLYTV 1632
             DV   ++ + WE   G+V +Y V Y +PE+ + E+    D  E +  L+ L   + YTV
Sbjct: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTV 1700

Query: 1633 SVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPF 1692
            SV A+HD+ ES P+   ++T  +PAPT+LK T+VT       W      ++ YR+   P 
Sbjct: 1701 SVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759

Query: 1693 GSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQA 1751
              +  M+ I L  D +++V   L   T YEVS+ A+        D + S     ++TT  
Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL-------KDTLTSRPAQGVVTTLE 1812

Query: 1752 PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQ 1811
              S PR  +V +AT  ++T+ W   +  +  +++   P+ G+   Q  TI     S  + 
Sbjct: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTIT 1871

Query: 1812 KLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871
             L+P T Y I + +L  +     +     T  ++   NLR    + ++L V W       
Sbjct: 1872 GLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARI 1930

Query: 1872 RQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVV 1914
              Y + Y      P E+VP P      A +  L+P T YT+ V+
Sbjct: 1931 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974



 Score =  296 bits (757), Expect = 3e-79
 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%)

Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056

Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114

Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170

Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230

Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288

Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347

Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399

Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458

Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578

Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P+ 
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637

Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 2089
            L       +S+ +AW+   G V +YR+ YS +  D I E    P G  +   LQ L+P +
Sbjct: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696

Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149
             Y ++V+A+++D +   L G  ++  +  P ++  +    T     W P    + GY++ 
Sbjct: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755

Query: 2150 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207
              P     PM+      + +S  +  L  +T Y+V+VYA  D+  S P     TTL  NV
Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814

Query: 2208 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263
            +  +  ++      T  + W +     T +++   PA+G    + T++    S+  TGL 
Sbjct: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874

Query: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292
            P TDY + ++    N     V +   T +
Sbjct: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903



 Score =  277 bits (709), Expect = 1e-73
 Identities = 256/949 (26%), Positives = 419/949 (44%), Gaps = 63/949 (6%)

Query: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441
            PG    P N  ++E T     ++WTP       +K+   P  GG+     V+    S V+
Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140

Query: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496
              L P  EYV  +  V+ D  E   P+     T   P  +L++    D G  T+  +   
Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556
                TGY ++  P    +    +EV +    +     +L P  EY V+V  V  D  S P
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258

Query: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612
            ++  +  +P +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +
Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316

Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672
              S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F 
Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375

Query: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731
              W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E
Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435

Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791
             ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + 
Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486

Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846
            G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP++      
Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541

Query: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902
                  ++V D   ++++V+W  +      Y++   P  G GP +      +     +  
Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601

Query: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960
            LQP   Y   VV VY +   G +    +T +  + R   +   +   +S+ + W+   G 
Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658

Query: 1961 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 2017
            V +YRV YS P DG    E    P G      L+ L P + Y+V++VAL+ D E  P   
Sbjct: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716

Query: 2018 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 2076
             Q   +P   P +L+    T  SLS  W   +  +  YR+  +P     P+ E    P  
Sbjct: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774

Query: 2077 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 2135
             ++V++  L   T Y+++V A+ +        G   T+  + PP+   ++D   T   +S
Sbjct: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833

Query: 2136 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 2194
            W      + G+++   P     P++  +  ++ SYT+  L P T Y + +Y   D+  S 
Sbjct: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893

Query: 2195 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 2252
            P+    +T     ++L+      ++  V W P RA  T Y +K   P    R      R 
Sbjct: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953

Query: 2253 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301
              T    TGL P T+Y + V     N +   + +    TV+ T   T P
Sbjct: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2001



 Score =  256 bits (655), Expect = 2e-67
 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%)

Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871

Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931

Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045

Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105

Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158

Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213

Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272

Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332

Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391

Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450

Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509

Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568

Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 2258
             T       L    +  D+  + W SP    + YR+   SP DG         G E +  
Sbjct: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688

Query: 2259 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 2304
              GL P ++Y V+V     ++E  P +  +      PT+      TP
Sbjct: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735



 Score =  217 bits (553), Expect = 1e-55
 Identities = 171/613 (27%), Positives = 275/613 (44%), Gaps = 32/613 (5%)

Query: 631  AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688
            A  PP DL F+ +     +  W+P    ++ ++ + Y     +++V  +  + S  +VVL
Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325

Query: 689  SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748
            ++L P T Y+V+V++ YE   S PL G + T     +P  +  +D T +SF + W     
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383

Query: 749  RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807
             +  YRI + P    G  RE   P ++   TL NL P T+Y VS++          L G 
Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443

Query: 808  AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866
             +T  V   PRDL V   T +++ +SW      V+ Y +TY    G    QE TV G  +
Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501

Query: 867  NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922
               + GLK G  Y ++V A+  +G GD+             E   P  +   D+ D SI 
Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 923  AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982
              W  +   V GYRV+         T  K    D     IE LQP  +Y +SV+A   SG
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 983  EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK 1042
            E +PL   A T + +  K L   +   +++++ W+   G+V  YRV Y     G   +  
Sbjct: 1620 ESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678

Query: 1043 VPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101
             P     T  L+ L+P + Y ++V+ ++   E +   G+ +TA    +P +LK +  T +
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736

Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161
            S    W P   ++ GY+V   P      + E+ + P  ++VV+  L   T Y+V+V+ + 
Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796

Query: 1162 DGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSW 1208
            D   S P  G               +T  ++TT+     +  E +T  + D V   +G  
Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PANGQT 1855

Query: 1209 SIGRANFRTVRSF 1221
             I R     VRS+
Sbjct: 1856 PIQRTIKPDVRSY 1868



 Score =  201 bits (510), Expect = 1e-50
 Identities = 157/551 (28%), Positives = 237/551 (43%), Gaps = 20/551 (3%)

Query: 635  PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693
            P+DL     T      +W      V  Y ITY E  G+  V     P S ++  +S LKP
Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510

Query: 694  ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749
               Y + V A    G     S P++    TE  K  P  ++VTD   +S  + W  +   
Sbjct: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1568

Query: 750  VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808
            V  YR+   P  G G ++  T  P+Q   T+E L P  +Y VSV  +  SG   PL   A
Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 809  ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYT-PVAGGETQEVTVRGDTTN 867
             T   R  P+ L  +D    ++K++W    G+V +Y VTY+ P  G         G+   
Sbjct: 1629 VTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686

Query: 868  TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927
              LQGL+ G++Y +SV AL+       L G  +T     +P DL    +T TS+ A WT 
Sbjct: 1687 AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTP 1744

Query: 928  APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987
                + GYRV            E NL  D+   ++  L   TKY +SV+A   +    P 
Sbjct: 1745 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1804

Query: 988  TGDATT-ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046
             G  TT E     +  +V + TE T+ ++W+     +  ++V   P      +   + P 
Sbjct: 1805 QGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1864

Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106
            V S  +  LQP T Y I +  +             +TA    +P NL+    T +S  V+
Sbjct: 1865 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA--IDAPSNLRFLATTPNSLLVS 1922

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTV--VLEELRAGTTYKVNVFGMFDGG 1164
            W+P    + GY + +   G   R  E+V  P        +  L  GT Y + V  + +  
Sbjct: 1923 WQPPRARITGYIIKYEKPGSPPR--EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980

Query: 1165 ESSPLVGQEMT 1175
            +S PL+G++ T
Sbjct: 1981 KSEPLIGRKKT 1991



 Score =  200 bits (508), Expect = 2e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679

Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738

Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798

Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858

Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912

Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972

Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031

Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089

Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142

Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257

Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316

Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376

Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436

Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304
             P + + + +TV   P +      TP
Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461



 Score =  194 bits (492), Expect = 1e-48
 Identities = 209/874 (23%), Positives = 361/874 (41%), Gaps = 76/874 (8%)

Query: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963

Query: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104

Query: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164

Query: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
              A  +S    +L P   Y V+V    +D  S+P++  +T       P +L+ T+   D+
Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282

Query: 739  FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796
             ++TW   P   +  + + Y PV   E   E++  P+     L NL+P T+Y VSV   Y
Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342

Query: 797  FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855
                 TPL G   T     +P  +  SD T ++  + W      +  Y + + P    G 
Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400

Query: 856  TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915
             +E  V     +  L  L  GT+Y +S+ AL        L G+ +T+ +   P+DL    
Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458

Query: 916  ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975
             T TS+   W +    VR YR+++     +    E  +P       I  L+P   Y I+V
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 976  FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
            +A    G+     +P++ +  TE+ + S+ ++V +  +N++ V W P+   V  YRV   
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089
            P +G G        P  T   ++ LQP   Y ++V      GE + L Q + T   R   
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--- 1634

Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP--YDNTVVLEEL 1147
            P+ L  +D  + S ++ WE   G+V  Y+VT+    D   + EL   P   ++T  L+ L
Sbjct: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGL 1692

Query: 1148 RAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
            R G+ Y V+V  + D  ES PL+G + T +   T
Sbjct: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726



 Score =  173 bits (438), Expect = 3e-42
 Identities = 209/923 (22%), Positives = 360/923 (39%), Gaps = 128/923 (13%)

Query: 334  VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392
            V PP++L    +    +++ W P PS  +T + V  +P+        LS+ P    + + 
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 393  DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450
            +L   TEY +SVS++     S P+   +KT           G+D    I F  +   S++
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAI 507
            +   +++  RA     +  + I  +    S   +  R PH+    TL   T   + + +I
Sbjct: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428

Query: 508  NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565
                 R  S             + +  + + S+VP+ + ++    +S   ++  PA+ +R
Sbjct: 1429 VALNGREES------------PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476

Query: 566  -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614
                       NS V+ F V      +S        P   +  TV      +  S   ++
Sbjct: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532

Query: 615  SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672
             I +    E+          P  +  ++V        W P+   V  Y +T   K   G 
Sbjct: 1533 PISINYRTEID--------KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584

Query: 673  DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732
             +     P   T + +  L+P   Y+V+V A+   G S PL     T   +  P+ L  T
Sbjct: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1641

Query: 733  DETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVS 791
            D   DS KI W    G+V RYR+ Y     G       P  +     L+ L P ++Y VS
Sbjct: 1642 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701

Query: 792  VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP- 850
            V+  +      PL G  +T      P DL+ +  T +++   W+    ++  Y V  TP 
Sbjct: 1702 VVALHDDMESQPLIGTQST--AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759

Query: 851  VAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD 910
               G  +E+ +  D+++ V+ GL   T+Y +SV AL  +       G  TTLE    P+ 
Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819

Query: 911  LVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETK 970
                D T+T+I   W +    + G++V            ++ +  D     I  LQP T 
Sbjct: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTD 1878

Query: 971  YRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY 1030
            Y+I ++    +    P+  DA+T +   S  L+    T N++ V+W+P   ++  Y + Y
Sbjct: 1879 YKIYLYTLNDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKY 1937

Query: 1031 -RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVL----------------------- 1066
             +P    +++V +  P VT   +  L+P T Y I V+                       
Sbjct: 1938 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997

Query: 1067 ---PIYKMGEG-KLRQGSGTTAS-----RFKSPRNLKTSDPT------------------ 1099
               P Y  G G +L   SG   S      F+     +T+ PT                  
Sbjct: 1998 VTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ 2057

Query: 1100 --MSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNV 1157
              +S   ++W P   +   Y ++ HP G D    +  V     +  L  L  G TY + V
Sbjct: 2058 EALSQTTISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2116

Query: 1158 FGMFDGGESSPLVGQEMTTLSDT 1180
              + D  +    V +E+ T+ ++
Sbjct: 2117 EALKD--QQRHKVREEVVTVGNS 2137



 Score =  161 bits (407), Expect = 1e-38
 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)

Query: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944

Query: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002

Query: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062

Query: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119

Query: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176

Query: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232

Query: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020
              +NL P  +Y +SV+      E  P++ D           L+      +TMRVTW P P
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291

Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
               + N+ V Y P  + ++ VA+  + P+  + VL  L P T Y ++V  +Y+  E    
Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350

Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
            +G   T     SP  +  SD T +SF V W      + GY++  HP     R  E  V  
Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408

Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179
              N++ L  L  GT Y V++  + +G E SPL+  + +T+SD
Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449



 Score =  155 bits (391), Expect = 8e-37
 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%)

Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695

Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755

Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815

Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875

Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935

Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993

Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052

Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107

Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D         
Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246
            + +  PL+   T L+L    D     + W+      S     T YR+  +P +G +G   
Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221

Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306
            E  V   ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270



 Score =  147 bits (370), Expect = 2e-34
 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)

Query: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917

Query: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977

Query: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035

Query: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148

Query: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266

Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
               P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P DN VVL 
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
             L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362



 Score =  105 bits (263), Expect = 5e-22
 Identities = 119/490 (24%), Positives = 188/490 (38%), Gaps = 49/490 (10%)

Query: 622  QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679
            Q L   +  A   P DL F++VT       W+P    +  Y   +T KE  G  +   + 
Sbjct: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771

Query: 680  PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739
            P SS SVV+S L   T Y V+V A  +   S P  G  TT E    PR  +VTD T  + 
Sbjct: 1772 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1830

Query: 740  KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799
             I+W      +  +++   P  G    + T  P+ R  T+  L P T Y++ +     + 
Sbjct: 1831 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1890

Query: 800  PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859
              +P+  +A+T      P +LR    T +++ +SW     ++  Y++ Y    G   +EV
Sbjct: 1891 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 1947

Query: 860  T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917
                R   T   + GL+ GT+Y + V AL  +   + L G   T+++       VT    
Sbjct: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQK----TPFVTHPGY 2003

Query: 918  DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977
            DT  G       G                  G++ + E+  H       P T       A
Sbjct: 2004 DTGNGIQLPGTSG-------------QQPSVGQQMIFEE--HGFRRTTPPTT-------A 2041

Query: 978  TYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGK 1037
            T       P   +             V +E  +   ++W P       Y +   P G  +
Sbjct: 2042 TPIRHRPRPYPPN-------------VGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDE 2087

Query: 1038 Q-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTS 1096
            + +  +VP T TS  L  L    TY+I V  +      K+R+   T  +      N  T 
Sbjct: 2088 EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTD 2147

Query: 1097 DPTMSSFRVT 1106
            D     + V+
Sbjct: 2148 DSCFDPYTVS 2157



 Score = 66.6 bits (161), Expect = 4e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859

Query: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916

Query: 134 SVS 136
            V+
Sbjct: 917 EVT 919



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600

Query: 83   ELVPETEYVVTITSYDEVEESVPVI 107
             L P  EYVV++ + +   ES P++
Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPLV 1625



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82
            V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    +L+
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 83   ELVPETEYVVTITSYDEVEESVPVIGQ 109
             L+P TEYVV+++S  E  ES P+ G+
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
            L+ +    +D P  L F  +D +++ ++W  P   +  YR+T     DG  + F      
Sbjct: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683

Query: 77   TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135
             +T  L  L P +EY V++ +  +  ES P+IG     T S+  P       T++   S+
Sbjct: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1738

Query: 136  SA-WT 139
            SA WT
Sbjct: 1739 SAQWT 1743



 Score = 48.9 bits (115), Expect = 8e-05
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773

Query: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 5/117 (4%)

Query: 313  ISQVCSGVDEQLGELVSGEEVVEP-PSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPM 371
            +S V    D +   L+  +    P P++L   +V+   +   W P    +TGY+V +TP 
Sbjct: 1700 VSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759

Query: 372  TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP----ISIMEKTQP 424
                    +++ P ++++ V  L   T+Y++SV A+K   +S P    ++ +E   P
Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849

Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223

Query: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 25/96 (26%), Positives = 44/96 (45%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            ++     ++ PSNL  +  +   + ++W P  + +TGY +      +  R+      P  
Sbjct: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            T  ++  L   TEY I V A+K    SEP+   +KT
Sbjct: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1991



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498

Query: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542

Query: 131  QKCSVSAWTDL 141
             K S    TD+
Sbjct: 1543 DKPSQMQVTDV 1553



 Score = 43.1 bits (100), Expect = 0.004
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 9/102 (8%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 1903 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP 125
            L P TEY + + +    ++S P+IG+         K V+K P
Sbjct: 1963 LEPGTEYTIYVIALKNNQKSEPLIGR--------KKTVQKTP 1996



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 1795 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1853

Query: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            +V+  E V PP      + +   + ++W      +TG++V   P   G      ++ P  
Sbjct: 1807 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1865

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446
             + ++  L   T+Y+I +  +     S P           V ++ S  +D  +++ FL  
Sbjct: 1866 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1914

Query: 447  GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494
               S+ + ++   RA +   +  +E  P      +V   R   TE T+
Sbjct: 1915 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1960



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797

Query: 102 ESVPVIGQLTIQTGSSTKP 120
           E       L + T  +T P
Sbjct: 798 EQ-----SLILSTSQTTAP 811



 Score = 32.7 bits (73), Expect = 5.7
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)

Query: 312  IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
            ++S V     E+   L+  +  V + P +L  +  +   + ++W+     V  Y++    
Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484

Query: 371  MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423
                S     +V    +T ++  L    +Y I+V A+ G      SS+PISI  +T+   
Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544

Query: 424  PMKVQV 429
            P ++QV
Sbjct: 1545 PSQMQV 1550


>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
          Length = 2355

 Score =  383 bits (983), Expect = e-105
 Identities = 357/1427 (25%), Positives = 593/1427 (41%), Gaps = 119/1427 (8%)

Query: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746

Query: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035

Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093

Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136

Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179

Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239

Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504
              EY V+VY+V +D+ S P+  T      P   L   ++GP TM V W P      T ++
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299

Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
            + Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V     S P+  R+ T 
Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356

Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621
             L  P  +   D+T ++  V W      +  Y +R+  PE      +E  V  S  S +L
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415

Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
             +L   T Y VS+ A++   ESP +  Q++T     P +L++   T      +WD  A  
Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474

Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
            V  YRIT+   G +S   E  + G ++T     L P   Y +++ A+    +   D   S
Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530

Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
             + + I   T+  K  P  +QV +   NS++VKW P+S  V  YR+T  P  G G  +T 
Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588

Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859
            T G  Q  + ++ L+P   Y ++V +  P GE   +     T  ++  + L   D    +
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDS 1647

Query: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVVPVYT 1918
            + + W+  +G   +Y++ Y+    G  EL P P G  + A L+ L+P + YTV+VV ++ 
Sbjct: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707

Query: 1919 EGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSE 1978
            + +      T  T +     +++    TP SL  +W P    +  YRV  +P + T P +
Sbjct: 1708 DMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766

Query: 1979 SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGET 2037
             I +  ++  V +  L+  T Y V++ AL       P+     TL   S PR  RV   T
Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826

Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097
              +++++W      +  +++   P  G    + T  P  R+  I   LQP T YKI +  
Sbjct: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI-TGLQPGTDYKIYLYT 1885

Query: 2098 VYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS-- 2155
            + ++     +  +  T  +  P N+           VSW P  + + GY I Y+  GS  
Sbjct: 1886 LNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1944

Query: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTT 2202
             E +      +T  T+  L P T Y + V A  ++  S PL  +  T
Sbjct: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1991



 Score =  334 bits (856), Expect = 9e-91
 Identities = 325/1304 (24%), Positives = 551/1304 (42%), Gaps = 84/1304 (6%)

Query: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786

Query: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844

Query: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904

Query: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963

Query: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079

Query: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136

Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195

Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255

Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225
            S P+    +  +   T +   + G + +    A          SI   NF    S +   
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308

Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280
             +V ++       A+   +  P TE+ ++      S+ +   + P +G      ++ TG+
Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364

Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340
              + I   +F T   + PRA   G  I              ++      +    +    E
Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423

Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400
              + ++A +  +     +    ++S                    + P +L +   T  S
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463

Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458
              +SW  P+ +V  Y++ Y    G    QEF V   +++  +  LKP  +Y + VY+V  
Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523

Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514
                   S+P+    +T       + + DV   ++ V+W P     TGY ++  P     
Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583

Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
            PT+ K    GP   +M +  L P  EY V+V A      S+P+    VT  + RP+ L  
Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAF 1640

Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EVDRSETSTSLKDLFSQTLYTV 1632
             DV   ++ + WE   G+V +Y V Y +PE+ + E+    D  E +  L+ L   + YTV
Sbjct: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTV 1700

Query: 1633 SVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPF 1692
            SV A+HD+ ES P+   ++T  +PAPT+LK T+VT       W      ++ YR+   P 
Sbjct: 1701 SVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759

Query: 1693 GSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQA 1751
              +  M+ I L  D +++V   L   T YEVS+ A+        D + S     ++TT  
Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL-------KDTLTSRPAQGVVTTLE 1812

Query: 1752 PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQ 1811
              S PR  +V +AT  ++T+ W   +  +  +++   P+ G+   Q  TI     S  + 
Sbjct: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTIT 1871

Query: 1812 KLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871
             L+P T Y I + +L  +     +     T  ++   NLR    + ++L V W       
Sbjct: 1872 GLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARI 1930

Query: 1872 RQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVV 1914
              Y + Y      P E+VP P      A +  L+P T YT+ V+
Sbjct: 1931 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974



 Score =  296 bits (757), Expect = 3e-79
 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%)

Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056

Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114

Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170

Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230

Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288

Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347

Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399

Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458

Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578

Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P+ 
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637

Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 2089
            L       +S+ +AW+   G V +YR+ YS +  D I E    P G  +   LQ L+P +
Sbjct: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696

Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149
             Y ++V+A+++D +   L G  ++  +  P ++  +    T     W P    + GY++ 
Sbjct: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755

Query: 2150 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207
              P     PM+      + +S  +  L  +T Y+V+VYA  D+  S P     TTL  NV
Sbjct: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814

Query: 2208 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263
            +  +  ++      T  + W +     T +++   PA+G    + T++    S+  TGL 
Sbjct: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874

Query: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292
            P TDY + ++    N     V +   T +
Sbjct: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903



 Score =  276 bits (705), Expect = 3e-73
 Identities = 253/942 (26%), Positives = 416/942 (44%), Gaps = 62/942 (6%)

Query: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441
            PG    P N  ++E T     ++WTP       +K+   P  GG+     V+    S V+
Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140

Query: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496
              L P  EYV  +  V+ D  E   P+     T   P  +L++    D G  T+  +   
Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556
                TGY ++  P    +    +EV +    +     +L P  EY V+V  V  D  S P
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258

Query: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612
            ++  +  +P +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +
Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316

Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672
              S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F 
Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375

Query: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731
              W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E
Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435

Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791
             ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + 
Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486

Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846
            G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP++      
Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541

Query: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902
                  ++V D   ++++V+W  +      Y++   P  G GP +      +     +  
Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601

Query: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960
            LQP   Y   VV VY +   G +    +T +  + R   +   +   +S+ + W+   G 
Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658

Query: 1961 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 2017
            V +YRV YS P DG    E    P G      L+ L P + Y+V++VAL+ D E  P   
Sbjct: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716

Query: 2018 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 2076
             Q   +P   P +L+    T  SLS  W   +  +  YR+  +P     P+ E    P  
Sbjct: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774

Query: 2077 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 2135
             ++V++  L   T Y+++V A+ +        G   T+  + PP+   ++D   T   +S
Sbjct: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833

Query: 2136 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 2194
            W      + G+++   P     P++  +  ++ SYT+  L P T Y + +Y   D+  S 
Sbjct: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893

Query: 2195 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 2252
            P+    +T     ++L+      ++  V W P RA  T Y +K   P    R      R 
Sbjct: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953

Query: 2253 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
              T    TGL P T+Y + V     N +   +  ++ T   P
Sbjct: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 1995



 Score =  256 bits (655), Expect = 2e-67
 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%)

Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871

Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931

Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045

Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105

Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158

Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213

Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272

Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332

Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391

Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450

Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509

Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568

Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 2258
             T       L    +  D+  + W SP    + YR+   SP DG         G E +  
Sbjct: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688

Query: 2259 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 2304
              GL P ++Y V+V     ++E  P +  +      PT+      TP
Sbjct: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735



 Score =  219 bits (559), Expect = 2e-56
 Identities = 236/938 (25%), Positives = 396/938 (42%), Gaps = 77/938 (8%)

Query: 631  AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688
            A  PP DL F+ +     +  W+P    ++ ++ + Y     +++V  +  + S  +VVL
Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325

Query: 689  SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748
            ++L P T Y+V+V++ YE   S PL G + T     +P  +  +D T +SF + W     
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383

Query: 749  RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807
             +  YRI + P    G  RE   P ++   TL NL P T+Y VS++          L G 
Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443

Query: 808  AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866
             +T  V   PRDL V   T +++ +SW      V+ Y +TY    G    QE TV G  +
Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501

Query: 867  NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922
               + GLK G  Y ++V A+  +G GD+             E   P  +   D+ D SI 
Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 923  AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982
              W  +   V GYRV+         T  K    D     IE LQP  +Y +SV+A   SG
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 983  EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK 1042
            E +PL   A T + +  K L   +   +++++ W+   G+V  YRV Y     G   +  
Sbjct: 1620 ESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678

Query: 1043 VPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101
             P     T  L+ L+P + Y ++V+ ++   E +   G+ +TA    +P +LK +  T +
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736

Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161
            S    W P   ++ GY+V   P      + E+ + P  ++VV+  L   T Y+V+V+ + 
Sbjct: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796

Query: 1162 DGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSW 1208
            D   S P  G               +T  ++TT+     +  E +T  + D V   +G  
Sbjct: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PANGQT 1855

Query: 1209 SIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVA 1267
             I R     VRS+ I+ +    D   K     L   +         +   D  S L+ +A
Sbjct: 1856 PIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLA 1913

Query: 1268 NLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320
              P             +TG  + + +  +   +   RPR       IT  +   +     
Sbjct: 1914 TTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973

Query: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT---INLCN 1377
              LK+       IG K  DE+  +++     + H   + D  S  +    +T    +  N
Sbjct: 1974 IALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGN 2032

Query: 1378 SVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVS 1433
             ++ PG   + PS    ++  E     FR +  P + +  R++   YP + G+      +
Sbjct: 2033 GIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYPPNVGQE-----A 2084

Query: 1434 RMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQ 1493
              +T+      +  +EY+++ + V  DE  EPL+       VP  S +    G T     
Sbjct: 2085 LSQTTISWAPFQDTSEYIISCHPVGTDE--EPLQ-----FRVPGTSTSATLTGLTR---- 2133

Query: 1494 WQPVGGATGYILSYKPVKDTEPTRPKE--VRLGPTVND 1529
                 GAT Y +  + +KD +  + +E  V +G +VN+
Sbjct: 2134 -----GAT-YNIIVEALKDQQRHKVREEVVTVGNSVNE 2165



 Score =  200 bits (508), Expect = 2e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679

Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738

Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798

Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858

Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912

Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972

Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031

Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089

Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142

Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257

Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316

Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376

Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436

Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304
             P + + + +TV   P +      TP
Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461



 Score =  194 bits (492), Expect = 1e-48
 Identities = 209/874 (23%), Positives = 361/874 (41%), Gaps = 76/874 (8%)

Query: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963

Query: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104

Query: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164

Query: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
              A  +S    +L P   Y V+V    +D  S+P++  +T       P +L+ T+   D+
Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282

Query: 739  FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796
             ++TW   P   +  + + Y PV   E   E++  P+     L NL+P T+Y VSV   Y
Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342

Query: 797  FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855
                 TPL G   T     +P  +  SD T ++  + W      +  Y + + P    G 
Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400

Query: 856  TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915
             +E  V     +  L  L  GT+Y +S+ AL        L G+ +T+ +   P+DL    
Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458

Query: 916  ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975
             T TS+   W +    VR YR+++     +    E  +P       I  L+P   Y I+V
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 976  FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
            +A    G+     +P++ +  TE+ + S+ ++V +  +N++ V W P+   V  YRV   
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089
            P +G G        P  T   ++ LQP   Y ++V      GE + L Q + T   R   
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--- 1634

Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP--YDNTVVLEEL 1147
            P+ L  +D  + S ++ WE   G+V  Y+VT+    D   + EL   P   ++T  L+ L
Sbjct: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGL 1692

Query: 1148 RAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
            R G+ Y V+V  + D  ES PL+G + T +   T
Sbjct: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726



 Score =  170 bits (430), Expect = 2e-41
 Identities = 178/759 (23%), Positives = 310/759 (40%), Gaps = 73/759 (9%)

Query: 334  VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392
            V PP++L    +    +++ W P PS  +T + V  +P+        LS+ P    + + 
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 393  DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450
            +L   TEY +SVS++     S P+   +KT           G+D    I F  +   S++
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAI 507
            +   +++  RA     +  + I  +    S   +  R PH+    TL   T   + + +I
Sbjct: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428

Query: 508  NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565
                 R  S             + +  + + S+VP+ + ++    +S   ++  PA+ +R
Sbjct: 1429 VALNGREES------------PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476

Query: 566  -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614
                       NS V+ F V      +S        P   +  TV      +  S   ++
Sbjct: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532

Query: 615  SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672
             I +    E+          P  +  ++V        W P+   V  Y +T   K   G 
Sbjct: 1533 PISINYRTEID--------KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584

Query: 673  DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732
             +     P   T + +  L+P   Y+V+V A+   G S PL     T   +  P+ L  T
Sbjct: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1641

Query: 733  DETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVS 791
            D   DS KI W    G+V RYR+ Y     G       P  +     L+ L P ++Y VS
Sbjct: 1642 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701

Query: 792  VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP- 850
            V+  +      PL G  +T      P DL+ +  T +++   W+    ++  Y V  TP 
Sbjct: 1702 VVALHDDMESQPLIGTQST--AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759

Query: 851  VAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD 910
               G  +E+ +  D+++ V+ GL   T+Y +SV AL  +       G  TTLE    P+ 
Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819

Query: 911  LVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETK 970
                D T+T+I   W +    + G++V            ++ +  D     I  LQP T 
Sbjct: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTD 1878

Query: 971  YRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY 1030
            Y+I ++    +    P+  DA+T +   S  L+    T N++ V+W+P   ++  Y + Y
Sbjct: 1879 YKIYLYTLNDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKY 1937

Query: 1031 -RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPI 1068
             +P    +++V +  P VT   +  L+P T Y I V+ +
Sbjct: 1938 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1976



 Score =  161 bits (407), Expect = 1e-38
 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)

Query: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944

Query: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002

Query: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062

Query: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119

Query: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176

Query: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232

Query: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020
              +NL P  +Y +SV+      E  P++ D           L+      +TMRVTW P P
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291

Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
               + N+ V Y P  + ++ VA+  + P+  + VL  L P T Y ++V  +Y+  E    
Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350

Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
            +G   T     SP  +  SD T +SF V W      + GY++  HP     R  E  V  
Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408

Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179
              N++ L  L  GT Y V++  + +G E SPL+  + +T+SD
Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449



 Score =  155 bits (391), Expect = 8e-37
 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%)

Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695

Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755

Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815

Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875

Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935

Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993

Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052

Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107

Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D         
Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246
            + +  PL+   T L+L    D     + W+      S     T YR+  +P +G +G   
Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221

Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306
            E  V   ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270



 Score =  147 bits (370), Expect = 2e-34
 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)

Query: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917

Query: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977

Query: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035

Query: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148

Query: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266

Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
               P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P DN VVL 
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
             L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362



 Score =  105 bits (262), Expect = 7e-22
 Identities = 125/491 (25%), Positives = 193/491 (39%), Gaps = 26/491 (5%)

Query: 622  QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679
            Q L   +  A   P DL F++VT       W+P    +  Y   +T KE  G  +   + 
Sbjct: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771

Query: 680  PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739
            P SS SVV+S L   T Y V+V A  +   S P  G  TT E    PR  +VTD T  + 
Sbjct: 1772 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1830

Query: 740  KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799
             I+W      +  +++   P  G    + T  P+ R  T+  L P T Y++ +     + 
Sbjct: 1831 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1890

Query: 800  PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859
              +P+  +A+T      P +LR    T +++ +SW     ++  Y++ Y    G   +EV
Sbjct: 1891 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 1947

Query: 860  T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917
                R   T   + GL+ GT+Y + V AL  +   + L G   T E    PQ LVT    
Sbjct: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE---LPQ-LVTLPHP 2003

Query: 918  DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEK-NLPEDAIHTMIENLQPETKYRISVF 976
            +   G      P  V+         Y   DTG    LP  +        QP    ++ +F
Sbjct: 2004 NLH-GPEILDVPSTVQKTPFVTHPGY---DTGNGIQLPGTS------GQQPSVGQQM-IF 2052

Query: 977  ATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRG 1036
              +      P T               V +E  +   ++W P       Y +   P G  
Sbjct: 2053 EEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIISCHPVGTD 2111

Query: 1037 KQ-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKT 1095
            ++ +  +VP T TS  L  L    TY+I V  +      K+R+   T  +      N  T
Sbjct: 2112 EEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPT 2171

Query: 1096 SDPTMSSFRVT 1106
             D     + V+
Sbjct: 2172 DDSCFDPYTVS 2182



 Score = 85.9 bits (211), Expect = 6e-16
 Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 61/497 (12%)

Query: 334  VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
            ++ PS +   +V    + + W PS SPVTGY+V  TP          + GP  T +++  
Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601

Query: 394  LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGV---DIKADIVFLVDGSYS 450
            L    EY +SV A      S+P+      Q     ++  +G+   D+  D + +   S  
Sbjct: 1602 LQPTVEYVVSVYAQNPSGESQPL-----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ 1656

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              ++ +    +  E  +     +P+  + +       P +E+T+      +D    + + 
Sbjct: 1657 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD----MESQ 1712

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK------VMILITDGKSSDAFRDPAIKL 564
            P  G  +    A T ++     P+  S    P         + +T  + +   ++  I L
Sbjct: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE--INL 1770

Query: 565  RNSDVEIFAVGVKDAVRSEL------EAIASPPAETHVFTVEDFDAFQRISFELTQSICL 618
                  +   G+  A + E+      + + S PA+  V T+E+                 
Sbjct: 1771 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS--------------- 1815

Query: 619  RIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
                           PP+    ++ T      +W    E +  + +    A G   +   
Sbjct: 1816 ---------------PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
                  S  ++ L+P T Y + +    ++  S P+  + +T     AP NL+    T +S
Sbjct: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST--AIDAPSNLRFLATTPNS 1918

Query: 739  FKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQ--RRRTLENLIPDTKYEVSVIPEY 796
              ++W     R+  Y I Y    G   REV   P       T+  L P T+Y + VI   
Sbjct: 1919 LLVSWQPPRARITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK 1977

Query: 797  FSGPGTPLTGNAATEEV 813
             +    PL G   T+E+
Sbjct: 1978 NNQKSEPLIGRKKTDEL 1994



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 84/359 (23%), Positives = 144/359 (40%), Gaps = 55/359 (15%)

Query: 1384 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 1443
            ++  P    +++ T  +  +SW   ++++  ++V+  P +G    +  +     S  +  
Sbjct: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1872

Query: 1444 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 1502
            L+P T+Y + +Y++ ++  S P+     T      +L      P ++ V WQP     TG
Sbjct: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1932

Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 1561
            YI+ Y+  K   P R    R  P V +  +T L P TEY + V A+ ++  SEP+  R+ 
Sbjct: 1933 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990

Query: 1562 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 1614
                   VTLP P     ++ DV  +     +   PG        Y T    ++      
Sbjct: 1991 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2041

Query: 1615 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRG 1673
             + S   + +F +  +            +PP TA     RP P P N+            
Sbjct: 2042 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNV------------ 2080

Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFENLNPNTIYEVSITAI 1727
                G   +S   I+WAPF   D  E I++      DE  L F    P T    ++T +
Sbjct: 2081 ----GQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR--VPGTSTSATLTGL 2131



 Score = 66.6 bits (161), Expect = 4e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859

Query: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916

Query: 134 SVS 136
            V+
Sbjct: 917 EVT 919



 Score = 59.7 bits (143), Expect = 4e-08
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600

Query: 83   ELVPETEYVVTITSYDEVEESVPVI 107
             L P  EYVV++ + +   ES P++
Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPLV 1625



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82
            V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    +L+
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 83   ELVPETEYVVTITSYDEVEESVPVIGQ 109
             L+P TEYVV+++S  E  ES P+ G+
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
            L+ +    +D P  L F  +D +++ ++W  P   +  YR+T     DG  + F      
Sbjct: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683

Query: 77   TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135
             +T  L  L P +EY V++ +  +  ES P+IG     T S+  P       T++   S+
Sbjct: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1738

Query: 136  SA-WT 139
            SA WT
Sbjct: 1739 SAQWT 1743



 Score = 48.9 bits (115), Expect = 8e-05
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773

Query: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 5/117 (4%)

Query: 313  ISQVCSGVDEQLGELVSGEEVVEP-PSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPM 371
            +S V    D +   L+  +    P P++L   +V+   +   W P    +TGY+V +TP 
Sbjct: 1700 VSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759

Query: 372  TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP----ISIMEKTQP 424
                    +++ P ++++ V  L   T+Y++SV A+K   +S P    ++ +E   P
Sbjct: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849

Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223

Query: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 25/99 (25%), Positives = 45/99 (45%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            ++     ++ PSNL  +  +   + ++W P  + +TGY +      +  R+      P  
Sbjct: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425
            T  ++  L   TEY I V A+K    SEP+   +KT  +
Sbjct: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1994



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498

Query: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542

Query: 131  QKCSVSAWTDL 141
             K S    TD+
Sbjct: 1543 DKPSQMQVTDV 1553



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 1903 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEY + + +    ++S P+IG+
Sbjct: 1963 LEPGTEYTIYVIALKNNQKSEPLIGR 1988



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 1795 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1853

Query: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            +V+  E V PP      + +   + ++W      +TG++V   P   G      ++ P  
Sbjct: 1807 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1865

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446
             + ++  L   T+Y+I +  +     S P           V ++ S  +D  +++ FL  
Sbjct: 1866 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1914

Query: 447  GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494
               S+ + ++   RA +   +  +E  P      +V   R   TE T+
Sbjct: 1915 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1960



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797

Query: 102 ESVPVIGQLTIQTGSSTKP 120
           E       L + T  +T P
Sbjct: 798 EQ-----SLILSTSQTTAP 811



 Score = 32.7 bits (73), Expect = 5.7
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)

Query: 312  IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
            ++S V     E+   L+  +  V + P +L  +  +   + ++W+     V  Y++    
Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484

Query: 371  MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423
                S     +V    +T ++  L    +Y I+V A+ G      SS+PISI  +T+   
Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544

Query: 424  PMKVQV 429
            P ++QV
Sbjct: 1545 PSQMQV 1550


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score =  382 bits (981), Expect = e-105
 Identities = 291/935 (31%), Positives = 389/935 (41%), Gaps = 214/935 (22%)

Query: 2314 RDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVK 2373
            R  C+ A  D+VF+ D S+S+G +NF  V K++ N    FD I P  IQV  VQYSD   
Sbjct: 28   RSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFD-IGPKFIQVGVVQYSDYPV 86

Query: 2374 SEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVT 2433
             E  L +Y+       A+++I Y GGNT+TGKA+ F  + +    S   + + K+ VV+T
Sbjct: 87   LEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSS---RFLTKIAVVLT 143

Query: 2434 DGRSQDEVKKAALVIQQSGFSVFVVGV-ADVDYNELANIASKPSERHVFIVDDFESFEKI 2492
            DG+SQD+VK AA   + S  ++F +GV ++ +  EL  IA+KPS  +VF V+D+ +  KI
Sbjct: 144  DGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKI 203

Query: 2493 EDNLITFVCETATSSCPL-IYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYS 2551
             + +   +CE   S CP  I +      GF +L   ++ +K    +Q       S     
Sbjct: 204  REVMKQKLCEE--SVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQL------SPKKIK 255

Query: 2552 AYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVI 2611
             Y +     +++ T+++ P GLPPSY  +   R   +   D   +W+I   D +PQ+ V 
Sbjct: 256  GYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFKVKKIWD---LWRILTIDGRPQIAVT 312

Query: 2612 ADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIE 2671
             +   K L F         Q VTF   +VKTLF   +H++ ++VT + V +YID  +I  
Sbjct: 313  LNGVDKILLFTTTSVINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIEN 372

Query: 2672 KDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDE-- 2729
            K +     I  +G   +GK   G+ ++  F +Q   I C P   +R+  C+IP    E  
Sbjct: 373  KPLHPVLGILINGQTQIGKY-SGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECL 431

Query: 2730 ---GKCPAFPNSCTCTQDSVGPPGP----------------------------------- 2751
                   + P  C C     G  GP                                   
Sbjct: 432  NGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPG 491

Query: 2752 ----------PGPAGGPGAKGPRGERGISG---AIGPPGPRGDIGPPGPQGPPGPQGPNG 2798
                      PG  G PG  G +G+RG+ G     G PG +G++G  G +G PG  G  G
Sbjct: 492  SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKG 551

Query: 2799 LS----------IPG---EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 2845
                        +PG   E GR G  G  G PG  G  G+PG PG  G  G PG  GF G
Sbjct: 552  AKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPG 611

Query: 2846 KDGAMGPRGPPGPP------------------GSPGSPGVTGPSGKPGKPGDHGRPGPSG 2887
              G MG +G  GPP                  GSPG PG  G  G  G+PG  G PG SG
Sbjct: 612  NRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASG 671

Query: 2888 LKGEKGDRGDIASQNMMRAVARQ--------VCEQLISGQMNRFNQMLNQIPNDY----- 2934
            LKGE G  G       M     Q          E+ I GQ     +    IP        
Sbjct: 672  LKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGR--QGIPGQQGIQGH 729

Query: 2935 ------QSSRNQP------------------GPPGPPGPPGSAGARGEPGPGGRP----- 2965
                  +  + +P                  GP GP G PG  G +G PG  G+P     
Sbjct: 730  HGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFS 789

Query: 2966 --------------------------------------GFPGTPGMQGPPGERGLPGEKG 2987
                                                  G PG PG  GP G RGLPG  G
Sbjct: 790  EQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPG 849

Query: 2988 ERGT-------GSSGPRGLPGPPGPQGE---------SRTGPPGSTGSRGPP-----GPP 3026
              G        G  G RGL G PG  GE            GPPG  G  GPP     GPP
Sbjct: 850  RDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPP 909

Query: 3027 GRP---------GNSGIRGPPGPPGYCDSSQCASI 3052
            G P         G  GI+G PGPPG CD S C S+
Sbjct: 910  GDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSV 944



 Score =  198 bits (504), Expect = 6e-50
 Identities = 129/352 (36%), Positives = 156/352 (44%), Gaps = 46/352 (13%)

Query: 2747 GPPGPPGPAGGPGAKGPRGE---RGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIP 2802
            G  G  G AG PG  GP GE    G  G +G PG +G+ G PG  G  G +G  G+   P
Sbjct: 551  GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFP 610

Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP 2862
            G +G  G KG+ G PG  G+ G PG+PG  G  G PG  G  G  G+ G  G  G PG+ 
Sbjct: 611  GNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGAS 670

Query: 2863 GSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC--EQLISGQM 2920
            G  G  G +G PG+PG  G PG  G KG+KG++G+   Q       RQ    +Q I G  
Sbjct: 671  GLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHH 730

Query: 2921 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 2980
                +         +  + +PG  G  G  G +G  G  GP G  G PG PG QGPPG  
Sbjct: 731  GAKGE---------RGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLD 781

Query: 2981 GLPGEKG-----------------------------ERGTGSSGPRGLPGPPGPQG-ESR 3010
            G PG +                              +      G  G+PGPPGP G E  
Sbjct: 782  GKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGP 841

Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG-QGYPG 3061
             G PG  G  G PG  G PG  G+RG  G PG           Y G QG PG
Sbjct: 842  RGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPG 893



 Score =  131 bits (329), Expect = 1e-29
 Identities = 85/243 (34%), Positives = 132/243 (54%), Gaps = 28/243 (11%)

Query: 440 DIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTK 499
           D+VF++DGSYS+G  NF  V+ +L  + K+F+I P  +Q+ +VQYS  P  E  L  +  
Sbjct: 37  DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96

Query: 500 VEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRD 559
            E +  A+ +  Y GG+T TGKA+ +  + +F  +K SR  + K+ +++TDGKS D  +D
Sbjct: 97  GEHLTAAVESILYLGGNTKTGKAIQFALDYLF--AKSSRF-LTKIAVVLTDGKSQDDVKD 153

Query: 560 PAIKLRNSDVEIFAVGV-KDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSIC- 617
            A   R+S + +FA+GV  +   +EL AIA+ P+ T+VF VED+ A  +I   + Q +C 
Sbjct: 154 AAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKLCE 213

Query: 618 -----------LRIEQEL---------AAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGE 657
                       R E+             +KK+  + PK +   EVTS   K + S    
Sbjct: 214 ESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQLSPKKIKGYEVTS---KVDLSELTS 270

Query: 658 NVF 660
           NVF
Sbjct: 271 NVF 273



 Score =  128 bits (322), Expect = 8e-29
 Identities = 72/209 (34%), Positives = 116/209 (55%), Gaps = 10/209 (4%)

Query: 1196 AEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNA 1255
            A  D+V ++DGS+S+G  NF  V+ ++  I + FDIGPK +Q+ + QYS  P  E  L +
Sbjct: 34   APTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGS 93

Query: 1256 HRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDD 1315
            +   + L  AV ++ Y GGNT TG A+ F     F   +       KI V++TDGKSQDD
Sbjct: 94   YDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRF---LTKIAVVLTDGKSQDD 150

Query: 1316 VEAPSKKLKDEGVELFAIGI-KNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTIN 1374
            V+  ++  +D  + LFAIG+    ++ EL+ IA  P  T+ + V D+ ++S+I + +   
Sbjct: 151  VKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQK 210

Query: 1375 LCNSVKGPGDLEAPSNLVISERTHRSFRV 1403
            LC       +   P+ + ++ R  R F +
Sbjct: 211  LCE------ESVCPTRIPVAARDERGFDI 233



 Score =  128 bits (321), Expect = 1e-28
 Identities = 83/241 (34%), Positives = 135/241 (56%), Gaps = 10/241 (4%)

Query: 129 EIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDT 188
           E++    +A TDLVF++DGS+SVG  NF+ +  ++  +   FDIG +  +VGVVQYS   
Sbjct: 26  EVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYP 85

Query: 189 RTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIII 248
             E  L  Y   + L AA++ I Y GGNT TG AI + +   F +S+       K+A+++
Sbjct: 86  VLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRF---LTKIAVVL 142

Query: 249 TDGKSQDEVEIPARELRNVGVEVFSLGI-KAADAKELKQIASTPSLNHVFNVANFDAIVD 307
           TDGKSQD+V+  A+  R+  + +F++G+    +  EL+ IA+ PS  +VF V ++ AI  
Sbjct: 143 TDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISK 202

Query: 308 IQNEIISQVC--SGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYK 365
           I+  +  ++C  S    ++      E   +    L+ ++V+ K VK     SP  + GY+
Sbjct: 203 IREVMKQKLCEESVCPTRIPVAARDERGFD---ILLGLDVNKK-VKKRIQLSPKKIKGYE 258

Query: 366 V 366
           V
Sbjct: 259 V 259



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 29/80 (36%), Positives = 33/80 (41%), Gaps = 8/80 (10%)

Query: 2982 LPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041
            +PG  GE   G S     P P         G PG  G +G PG PG PG  G  G  G P
Sbjct: 423  IPGFNGECLNGPSDVGSTPAPC----ICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKP 478

Query: 3042 GYCDSSQCASIPYNGQGYPG 3061
            GY   +    +P    G PG
Sbjct: 479  GYQGIAGTPGVP----GSPG 494


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  352 bits (902), Expect = 4e-96
 Identities = 304/1020 (29%), Positives = 470/1020 (46%), Gaps = 57/1020 (5%)

Query: 1192 CLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFD--IGPKRVQIALAQYSGDPRT 1249
            C     ADIV L+DGS SIGR+NFR VRSF+  +V  F      + V+ A  QYS DPRT
Sbjct: 31   CTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRT 90

Query: 1250 EWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITD 1309
            E+ L+A      +++A+  L YKGGNT TG A+  +    F  Q   RP   K+ +LITD
Sbjct: 91   EFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA-RPGVPKVCILITD 149

Query: 1310 GKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVD 1369
            GKSQD V+  +++LK +GV+LFA+GIKNAD  ELK +A+ P     + V DF  L  ++ 
Sbjct: 150  GKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLP 209

Query: 1370 DLTINLCNSVKG------PGD-LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPV 1422
             ++  +C +  G      P D   AP +LV+SE + +S RV WT  S  V  YKV+Y P+
Sbjct: 210  LVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPL 269

Query: 1423 SG------GKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVP 1476
            +G       +RQE  V   ETS  L+ L+P TEY V V ++  +   E + GT +T  + 
Sbjct: 270  TGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALE 329

Query: 1477 VVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLV 1536
               L I +    ++ V W+ V GATGY ++++ V    PT+ +E  LGP    + L DL 
Sbjct: 330  GPELTIQNTTAHSLLVAWRSVPGATGYRVTWR-VLSGGPTQQQE--LGPGQGSVLLRDLE 386

Query: 1537 PNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY 1596
            P T+Y VTV + L   +  P T           Q L+   +  +++ + W  VP + R Y
Sbjct: 387  PGTDYEVTV-STLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVP-EARGY 444

Query: 1597 IV--RYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAV---HDEGESPPVTAQET 1651
             +  R +T  E  ++V +    T   L  L   T Y +++  +   H+      V     
Sbjct: 445  RLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGP 504

Query: 1652 TRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVF 1711
              PV   T+L+ TE+  +  R +W       + YRI        ++   +L G +     
Sbjct: 505  ELPVSPVTDLQATELPGQRVRVSWS-PVPGATQYRIIVRSTQGVER-TLVLPGSQTAFDL 562

Query: 1712 ENLNPNTIYEVSITA-IYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLT 1770
            +++     Y V ++A + P E       GS   L +            L+V  + +  + 
Sbjct: 563  DDVQAGLSYTVRVSARVGPRE-------GSASVLTVRREPETPLAVPGLRVVVSDATRVR 615

Query: 1771 VKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDG 1830
            V W P  G    +RI++  STG G E + T+     +  +  L+P T Y + VS L    
Sbjct: 616  VAWGPVPG-ASGFRISW--STGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672

Query: 1831 EGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVP 1890
            EG       +T PL  VR + V   S+S++ + W    G    Y++ +  +A GPE+   
Sbjct: 673  EGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRVSW-HSAHGPEKSQL 730

Query: 1891 IPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPN 1948
            + G    A L  L+PDT YTV V       DG   S   RT    + R   +Q+ N + +
Sbjct: 731  VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSD 790

Query: 1949 SLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALY 2008
             L + W    G    YR+ +   +G  P    ++PGNT    +  L     YSV + AL 
Sbjct: 791  VLRITWVGVTG-ATAYRLAWGRSEG-GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALV 848

Query: 2009 SDGEGNPSPAQGRTLPRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDP 2066
             D EG P      T P + P    L V     +SL + W+      Q + + + P  G  
Sbjct: 849  GDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVP-RAQGFLLHWQPEGGQ- 906

Query: 2067 IDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVG-LLPPQNIHIS 2125
             ++   +    ++  L  L+P T Y++ +  +   G+G       RT    +P   + + 
Sbjct: 907  -EQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVV 965

Query: 2126 DEWYTRFRVSWDPSPSPVLGYKIVYKPV---GSNEP--MEAFVGEMTSYTLHNLNPSTTY 2180
            D       ++W P  S    Y + ++P+   G   P   +   G  +S  +  L P  +Y
Sbjct: 966  DTSIDSVTLAWTP-VSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024



 Score =  266 bits (681), Expect = 2e-70
 Identities = 234/752 (31%), Positives = 344/752 (45%), Gaps = 46/752 (6%)

Query: 439  ADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFE--ISPNRVQISLVQYSRDPHTEFTLKK 496
            ADIVFL+DGS SIG +NF +VR+FLE LV  F    S   V+ + VQYS DP TEF L  
Sbjct: 37   ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96

Query: 497  FTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDA 556
                 D+I AI    Y+GG+T TG A+ +V + +F+P   +R  VPKV ILITDGKS D 
Sbjct: 97   LGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL-ARPGVPKVCILITDGKSQDL 155

Query: 557  FRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616
                A +L+   V++FAVG+K+A   EL+ +AS P     F V DF   + +   +++ +
Sbjct: 156  VDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRV 215

Query: 617  CLRI-EQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAG---- 671
            C       +      +   P+DL  SE +S   +  W+ A   V  Y + Y    G    
Sbjct: 216  CTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQP 275

Query: 672  --DDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNL 729
               +   V  PA  TSV L  L+P T Y V V A Y +     ++G   T  ++G    L
Sbjct: 276  LPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP--EL 333

Query: 730  KVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYE 789
             + + T  S  + W   PG    YR+ +R ++GG +++    P Q    L +L P T YE
Sbjct: 334  TIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYE 392

Query: 790  VSVIPEY--FSGPGTPLTG--NAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYL 845
            V+V   +    GP T L    +A+ E+       LR      +++ LSW+  P + + Y 
Sbjct: 393  VTVSTLFGRSVGPATSLMARTDASVEQT------LRPVILGPTSILLSWNLVP-EARGYR 445

Query: 846  VTYTPVAGGE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL-- 902
            + +    G E  Q+V +  D T   L GL+ GT+Y L+   LY    G  +    T +  
Sbjct: 446  LEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLT---LYTLLEGHEVATPATVVPT 502

Query: 903  --EERGSP-QDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIH 959
              E   SP  DL   ++    +   W+  PG  + YR+  +S      T    LP     
Sbjct: 503  GPELPVSPVTDLQATELPGQRVRVSWSPVPGATQ-YRIIVRSTQGVERT--LVLPGSQTA 559

Query: 960  TMIENLQPETKYRISVFATYSSGEGEP--LTGDATTELSQDSKTLKVDEETENTMRVTWK 1017
              ++++Q    Y + V A     EG    LT     E       L+V       +RV W 
Sbjct: 560  FDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWG 619

Query: 1018 PAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
            P PG    +R+ +   G G +    +PP  T+T +  LQP TTY + V  +    EG   
Sbjct: 620  PVPG-ASGFRISWST-GSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAA 677

Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
                 T       R +  +  + SS  +TW   PG   GY+V++H      +  +LV G 
Sbjct: 678  VIVART-DPLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRVSWHSAHGPEK-SQLVSG- 733

Query: 1138 YDNTVV-LEELRAGTTYKVNVFGMFDGGESSP 1168
             + TV  L+ L   T Y V+V     G +  P
Sbjct: 734  -EATVAELDGLEPDTEYTVHVRAHVAGVDGPP 764



 Score =  263 bits (672), Expect = 2e-69
 Identities = 262/1054 (24%), Positives = 441/1054 (41%), Gaps = 91/1054 (8%)

Query: 1489 TMHVQWQPVGG-ATGYILSYKPVKDTE---PTRPKEVRLGPTVNDMQLTDLVPNTEYAVT 1544
            ++ VQW    G  TGY + Y P+       P+  +EV +      ++L  L P TEY VT
Sbjct: 247  SLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVT 306

Query: 1545 VQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPE 1604
            V A+  +   E V+    T  L  P+ L +++ T  ++ V W  VPG     +       
Sbjct: 307  VIALYANSIGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPGATGYRVTWRVLSG 365

Query: 1605 EDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVT--------AQETTRPVP 1656
               ++ E+   + S  L+DL   T Y V+VS +      P  +         ++T RPV 
Sbjct: 366  GPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRPVI 425

Query: 1657 -APTNLKITEVTSEGFRGTWDHGASDVSLYRITWA-PFGSSDKMETILNGDENTLVFENL 1714
              PT++ ++       RG           YR+ W    G     + +L  D      + L
Sbjct: 426  LGPTSILLSWNLVPEARG-----------YRLEWRRETGLEPPQKVVLPSDVTRYQLDGL 474

Query: 1715 NPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWD 1774
             P T Y +++  +          + +  T+     + P S   +LQ        + V W 
Sbjct: 475  QPGTEYRLTLYTLLEGHE-----VATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWS 529

Query: 1775 PASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGR 1834
            P  G  Q YRI  + +  +G E+T  + G Q +  L  ++    YT+ VS+     EG  
Sbjct: 530  PVPGATQ-YRIIVRST--QGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586

Query: 1835 --MTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP 1892
              +T R + +    V  LRV     + + V W    G    +++ ++  +G PE    +P
Sbjct: 587  SVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPG-ASGFRISWSTGSG-PESSQTLP 644

Query: 1893 GNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDV 1952
             ++    +  LQP T+Y V V  +    +G       RT   G  R V V   + +S+ +
Sbjct: 645  PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTI 704

Query: 1953 RWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGE 2012
             W   PG    YRV +    G  P +S +V G   +  L+ L PDT Y+V++ A  +  +
Sbjct: 705  TWTRVPGAT-GYRVSWHSAHG--PEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVD 761

Query: 2013 GNPSPAQGRTLPRSGPR--NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEY 2070
            G P+    RT P    R   L++   +++ L + W    G    YR+ +  + G P+  +
Sbjct: 762  GPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATA-YRLAWGRSEGGPM-RH 819

Query: 2071 TTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQ--NIHISDEW 2128
              +PG  ++  ++ L+    Y + V A+  D +G  ++    T    PP    +H+    
Sbjct: 820  QILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRG 879

Query: 2129 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDV--NVYA 2186
                R+ W+P P    G+ + ++P G  E       E++SY L  L P+T Y V  +V  
Sbjct: 880  EHSLRLRWEPVPR-AQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLG 938

Query: 2187 QYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ 2246
                G S  +T +  +  +   +L+      D+  + W+P   A+SY L   P  G  GQ
Sbjct: 939  PAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGP-GQ 997

Query: 2247 EI-----TVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301
            E+     T+ G  +S   TGL P   Y   +F  TP L+G                P   
Sbjct: 998  EVPGSPQTLPGISSSQRVTGLEPGVSY---IFSLTPVLDG-------------VRGPEAS 1041

Query: 2302 PTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVV---KFIFNTVGGFDEISP 2358
             T  P         VC    AD+VFL  A+     DN ++     + +   V     + P
Sbjct: 1042 VTQTP---------VCPRGLADVVFLPHAT----QDNAHRAEATRRVLERLVLALGPLGP 1088

Query: 2359 AGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYR--GGNTRTGKALTFIKEKVLT 2416
              +QV  + YS      F LN  +D  + L  ++++ Y    GN      +T  +  +  
Sbjct: 1089 QAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAP 1148

Query: 2417 WESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIA-SKP 2475
               G R++VP V+V++ D   + ++       Q SG +V ++G+A  D  +L  +A    
Sbjct: 1149 DAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMD 1208

Query: 2476 SERHVFIVDDFESFEKIEDNLITFVCETATSSCP 2509
            S +  F VDD  S ++    L T +C+ + ++ P
Sbjct: 1209 SVQTFFAVDDGPSLDQAVSGLATALCQASFTTQP 1242



 Score =  234 bits (597), Expect = 1e-60
 Identities = 145/331 (43%), Positives = 162/331 (48%), Gaps = 66/331 (19%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGP---------------PGPRGDIGPPGPQGPP 2791
            G PG PGP G PG +GPRG +G  GA G                PGP G  GP GP G P
Sbjct: 1326 GSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDP 1385

Query: 2792 GPQGPNGLSIPGEQGRQGMKGDAGEPG------LPGRTGTPGLPGPP---GPMGPPGDRG 2842
            GP+GP GL     +G +G +G+ G PG       PG  G PGLPG P   GP+GPPG +G
Sbjct: 1386 GPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445

Query: 2843 FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIAS 2900
              G D   G  G PG PGSPG  G  GP G  G  GD G PGP G  GEKG+RG    A 
Sbjct: 1446 EKG-DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAG 1504

Query: 2901 QNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG 2960
               +  VA                               +PG  GP GPPG  G +GE G
Sbjct: 1505 SRGLPGVA------------------------------GRPGAKGPEGPPGPTGRQGEKG 1534

Query: 2961 PGGRPGFPGT--PGMQGPPGERGLPGEKGERG-TGSSGPRG-----LPGPPGPQGE-SRT 3011
              GRPG P    P + GP GE+G  G  G RG TG  G RG     LPG PGP+G+    
Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR 1594

Query: 3012 GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            GP G TG  GPPG  G PG  G  G PGPPG
Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625



 Score =  233 bits (594), Expect = 2e-60
 Identities = 158/388 (40%), Positives = 185/388 (47%), Gaps = 95/388 (24%)

Query: 2747 GPPGPPGPAGGPGAKGP--------RGERGISGAIGPPGPR------GDIGPPGPQGPPG 2792
            GPPGP GP G PG +GP        +G++G  G  GPPGP       G+ G PG  G PG
Sbjct: 1374 GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP---PGPMGPPGDRGFTG---K 2846
            PQGP G   PG++G +G   D G PGLPG+ G+PG  GP   PG +GP GDRGF G   +
Sbjct: 1434 PQGPVGP--PGKKGEKGDSED-GAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGE 1490

Query: 2847 DGAMGPRGPPGPPGSPGSPGVT------------GPSGKPGKPGDHGRPGP--------S 2886
             G  G RGPPGP GS G PGV             GP+G+ G+ G+ GRPG         +
Sbjct: 1491 AGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVA 1550

Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLI----------------SGQMNRFNQMLNQI 2930
            G KGEKGD G    +        +    L+                 G   R     +  
Sbjct: 1551 GPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG 1610

Query: 2931 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP------GMQGPPGERGLPG 2984
            P   +    +PGPPGP GP G  G  GE G  G PG PG P      G++G PG RG  G
Sbjct: 1611 PPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVG 1670

Query: 2985 EKGERG----------TGSSGP---RGLPGPPGPQGE--------SRTGPPGSTGSRGPP 3023
            EKG++G           GSSGP   RG PGPPGP G            G PG  G  GP 
Sbjct: 1671 EKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPR 1730

Query: 3024 GP------PGRPGNSGI---RGPPGPPG 3042
            GP      PG PG  GI   RGPPGP G
Sbjct: 1731 GPKGDPGLPGAPGERGIEGFRGPPGPQG 1758



 Score =  231 bits (589), Expect = 8e-60
 Identities = 151/347 (43%), Positives = 167/347 (48%), Gaps = 51/347 (14%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQ 2805
            G PGP G  G PG  G RG  G  G  G  GPRG  GP G  G PGP G  GL+ P G Q
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 2806 GRQGMKGDAGEPGLPGR-----TGTPGLPGPPGP---MGP------PGDRGFTGKDGAMG 2851
            G  G+KG+ GE G PGR     TG  GLPGPPGP   +GP      PG  G TGK GA G
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260

Query: 2852 ---------PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP--GPSGLKGEKGDRGDIAS 2900
                      RG PG PGSPG PG  GP G+PG  G  G+   G  G KGEKG  G +A 
Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAG 2320

Query: 2901 QNMMRAVAR-------------QVCEQLISGQMNRFNQMLNQIPNDYQSSR--NQPGPPG 2945
              +    A+             +       G      Q     P  ++       PG PG
Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPG 2380

Query: 2946 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004
            PPGPPG  G  G PG  G PG  G PG  GP GE G PG  GERG  G  G  G+PGP G
Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440

Query: 3005 PQG-ESRTGPPGSTGSRGP--------PGPPGRPGNSGIRGPPGPPG 3042
            P G     GPPG++G +G         PGP G  G  GIRG  G PG
Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG 2487



 Score =  227 bits (578), Expect = 2e-58
 Identities = 154/386 (39%), Positives = 176/386 (45%), Gaps = 86/386 (22%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG------PGAKGPRGERGISGAIGPPGPRGDIGPPG 2786
            P  P+         G PG PG AGG      PG +G RGE+G  G  G  GP G  G PG
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085

Query: 2787 PQGPPGP--------------QGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGL 2828
            P GPPGP              QGP GL      PG  G QG KGD G PG+ G  G PG 
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145

Query: 2829 PGPPGPMGPPGDRGFTG---KDGAMGPRGPPGP------PGSPGSPGVT------GPSGK 2873
             G  G  G PG+RG  G   K G  GPRGPPGP      PG PG+PG+       GPSG 
Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205

Query: 2874 PGKPGDHGRPGPS--------GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925
             G+PG+ G PG          GL G  G  G +  Q     +  QV E    G   R   
Sbjct: 2206 KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG-SPGLPGQVGETGKPGAPGRDG- 2263

Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP-----GFPGTPGMQGPP--- 2977
                  +     R  PG PG PG PG  G +GEPGP G P     G PG  G +G P   
Sbjct: 2264 -----ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL 2318

Query: 2978 -----------GERGLPGEKGERG----------TGSSGPRGLPGPPGPQGESRTGPPGS 3016
                       G+RGLPG +GE+G           G  G +G PGP G +G+   G PGS
Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS 2378

Query: 3017 TGSRGPPGPPGRPGNSGIRGPPGPPG 3042
                GPPGPPG  G+ G+ G PG PG
Sbjct: 2379 P---GPPGPPGVKGDLGLPGLPGAPG 2401



 Score =  225 bits (574), Expect = 5e-58
 Identities = 149/372 (40%), Positives = 172/372 (46%), Gaps = 82/372 (22%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---------------QGPP 2791
            G PG  GP G PGA GP+G+RG  G +G  G +G+ GPPGP               +GP 
Sbjct: 1462 GSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPE 1521

Query: 2792 GPQGPNG-LSIPGEQGR--------------QGMKGDAGEPGLPGRTGTPG--------L 2828
            GP GP G     GE GR              +G KGD G  G  G TG  G        L
Sbjct: 1522 GPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVL 1581

Query: 2829 PGPPGPMGPPGDR---GFTGKDGAMGPRGPPGPPGSPGSPGVTGP------SGKPGKPGD 2879
            PG PGP G PGDR   G TG+ G  G  GPPG  G PG PG  GP       G+ G+ GD
Sbjct: 1582 PGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGD 1641

Query: 2880 HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939
             G PG  GL G+ G+RG +     +R    +  +Q   G+  R     +  P   +  R 
Sbjct: 1642 EGPPGDPGLPGKAGERG-LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGP---KGDRG 1697

Query: 2940 QPGPPGPP-------------GPPGSAGARGEPGPGGRPGFPGT------------PGMQ 2974
            +PGPPGPP             G PG  G  G  GP G PG PG             PG Q
Sbjct: 1698 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ 1757

Query: 2975 GPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRP---G 3030
            G PG RG  GEKG+RG  G  G  GL G PG  G S  GP G+ G  G PG  G P   G
Sbjct: 1758 GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS--GPNGAAGKAGDPGRDGLPGLRG 1815

Query: 3031 NSGIRGPPGPPG 3042
              G+ GP GPPG
Sbjct: 1816 EQGLPGPSGPPG 1827



 Score =  224 bits (572), Expect = 8e-58
 Identities = 140/341 (41%), Positives = 157/341 (46%), Gaps = 61/341 (17%)

Query: 2747 GPPGPPGPAGGPGA---KGPRGERG-------ISGAIGPPGPRGDIGPPGPQGPPG-PQG 2795
            GPPG  GP G PG    KG RG+ G         G  GPPGP G  G PG  G PG P  
Sbjct: 1988 GPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGR 2047

Query: 2796 PNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDR--------GFTGKD 2847
              G+   G  G +G +G+ GE G  GR G PGLPG PGP GPPG +        G +G+ 
Sbjct: 2048 AGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQ 2107

Query: 2848 GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
            G  G +G  G PGS G  G  G  G PG  GD G PGP G  G  G  G+       R +
Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGE-------RGM 2160

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967
            A                               +PG  GP GPPG  G  G+PGP G PG 
Sbjct: 2161 A---------------------------GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193

Query: 2968 PGTPGMQGPPGERGLPGEKGERGTGSSGPR---GLPGPPGPQG----ESRTGPPGSTGSR 3020
             G  G QGP G +G PGE G  G G +GP    GLPGPPGP G    +   G PG  G  
Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGET 2253

Query: 3021 GPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            G PG PGR G SG  G  G PG   S      P   +G PG
Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPG-PVGPKGEPG 2293



 Score =  223 bits (569), Expect = 2e-57
 Identities = 153/391 (39%), Positives = 177/391 (45%), Gaps = 81/391 (20%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRGDIGPPGPQGPPGPQG---PNG 2798
            GP GPPGP G  G KG  G  G    +GP      G +GD+GP GP+G  G QG   P G
Sbjct: 1519 GPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPG 1578

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPG---------PMGPPGDRGFTGKDGA 2849
            L +PG+ G +G  GD G  GL GR G PG  GPPG         P GP G RG  G+ G 
Sbjct: 1579 LVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE 1638

Query: 2850 MGPRGPPGPPGSP---------GSPGVTGP---SGKPGKPGDHGRPGPSGLKGEKGDRGD 2897
             G  GPPG PG P         G+PGV GP    G  G PG+ GR G  G  G KGDRG+
Sbjct: 1639 KGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE 1698

Query: 2898 IASQNMMRAV------ARQVCEQLISGQMN----RFNQMLNQIPND--YQSSRNQPGPPG 2945
                     +      AR+  E    GQ      + +  L   P +   +  R  PGP G
Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758

Query: 2946 PP---GPPGSAGARGEPGPGGRPGFPGTPGMQGP------------PGERGLPGEKGERG 2990
             P   GP G  G RG PG  GR G  G PG  GP            PG  GLPG +GE+G
Sbjct: 1759 DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQG 1818

Query: 2991 -TGSSGPRGLPGPPGPQG-------------------ESRTGPPGSTGSRGPPGPPGRPG 3030
              G SGP GLPG PG  G                   +   G  G++G  G  GP G  G
Sbjct: 1819 LPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERG 1878

Query: 3031 NSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
              GI GP GPPG         +   GQG+PG
Sbjct: 1879 APGILGPQGPPGL-----PGPVGPPGQGFPG 1904



 Score =  222 bits (565), Expect = 5e-57
 Identities = 134/350 (38%), Positives = 164/350 (46%), Gaps = 56/350 (16%)

Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            D VG PG  G  G PG +G +GE G +G  G PG  G  G PGP+G  G  G      PG
Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPG 2380

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM------GPPGDRGFT---GKDGAMGPRG 2854
              G  G+KGD G PGLPG  G  G PG  GP       GP G+RG     G++G  GP G
Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440

Query: 2855 PPGPPGS--------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGL 2888
            PPGPPGS                           G PG+ G  G+PG+ G  G  GP G 
Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGS 2500

Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948
            +GE+G++GD+ S  +              G       M  + P      +   GP G  G
Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDK---GPRGDNG 2557

Query: 2949 PPGSAGARGEP---------------GPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TG 2992
             PG  G++GEP               GP G+PG  G PG  G PG+ G+PG +GE+G  G
Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617

Query: 2993 SSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              GPRGL G  G +G    G  G  G +G  GPPGRPG +G +G  G PG
Sbjct: 2618 FMGPRGLKGERGVKG--ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPG 2665



 Score =  221 bits (562), Expect = 1e-56
 Identities = 141/354 (39%), Positives = 173/354 (48%), Gaps = 71/354 (20%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP---PGPQGPNGLS-I 2801
            +GPPGPPG  G PGA G +G++G  G +G PGPRG+ G PG +G    PG +GP GL+  
Sbjct: 2439 LGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP 2497

Query: 2802 PGEQGRQGMKGDAGEPGLPGRTGTPG-LPGPPGPMGPPGD---RGFTGKDGAMGPRGPPG 2857
            PG +G +G KGD G  GL G  G    + GPPGP G  GD   RG  G DG  GPRG  G
Sbjct: 2498 PGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNG 2557

Query: 2858 PPGS---------------PGSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIA 2899
             PG                PG  G+ GP G+PG    PGD G PG  G+ G +G++GD+ 
Sbjct: 2558 DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617

Query: 2900 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 2959
                         E+ + G      +         +  + + GPPG PG  G  G  GEP
Sbjct: 2618 FMGPRGLKG----ERGVKGACGLDGE---------KGDKGEAGPPGRPGLAGHKGEMGEP 2664

Query: 2960 GPGGRPGFPGTPGMQGPPGERGLPG---------EKGERGT-------------GSSGPR 2997
            G  G+ G PG  G+ GP G+RG  G         EKGERGT             GS+GP 
Sbjct: 2665 GVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPP 2724

Query: 2998 GLPGPPGPQG-------ESRTGPPGS--TGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G PG  GP+G       +   GPPG    G+ G PG PG  G  G  GP GP G
Sbjct: 2725 GPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778



 Score =  218 bits (555), Expect = 7e-56
 Identities = 139/317 (43%), Positives = 153/317 (48%), Gaps = 52/317 (16%)

Query: 2748 PPGPPGPAGGP-GAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805
            P   P P   P G KG  GE G+ G +GPPG   D G PG  G PGPQGP G  +  GE+
Sbjct: 1242 PRPEPCPVYCPKGQKGEPGEMGLRGQVGPPG---DPGLPGRTGAPGPQGPPGSATAKGER 1298

Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGS---- 2861
            G  G  G  G PG  G  GTPG PG  G  G PG RG  G+ G  GP+G PG PG     
Sbjct: 1299 GFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGG 1358

Query: 2862 -----PGSPGVTGPSGKPGKPGDHGRPGPSG--------LKGEKGDRGDIASQNMMRAVA 2908
                 PG  G  GPSG PG  G  G PGP G        +KG+KGDRG+           
Sbjct: 1359 EGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPG---- 1414

Query: 2909 RQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARG--EPGPGGRPG 2966
                     G +      L  +P         PGP GP GPPG  G +G  E G  G PG
Sbjct: 1415 --------EGGIAPGEPGLPGLP-------GSPGPQGPVGPPGKKGEKGDSEDGAPGLPG 1459

Query: 2967 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGP 3025
             PG+PG QGP G  G  G KG+        RG PGP G  GE    GPPG  GSRG PG 
Sbjct: 1460 QPGSPGEQGPRGPPGAIGPKGD--------RGFPGPLGEAGEKGERGPPGPAGSRGLPGV 1511

Query: 3026 PGRPGNSGIRGPPGPPG 3042
             GRPG  G  GPPGP G
Sbjct: 1512 AGRPGAKGPEGPPGPTG 1528



 Score =  218 bits (555), Expect = 7e-56
 Identities = 136/362 (37%), Positives = 168/362 (46%), Gaps = 74/362 (20%)

Query: 2735 FPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ 2794
            FP   T  +  +G PGP   +G  G  GP G  GI G +GPPGP G +GPPG  G  G +
Sbjct: 2405 FPGQ-TGPRGEMGQPGP---SGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460

Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP-------------------- 2834
            G  G+ +PG +G +G  G  GE G PG+ G  GL GPPG                     
Sbjct: 2461 GDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520

Query: 2835 -----MGPP---------GDRGFTGKDGAMGPRGPPGPPGS---------------PGSP 2865
                 +GPP         G+RG  G DG  GPRG  G PG                PG  
Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580

Query: 2866 GVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNR 2922
            G+ GP G+PG    PGD G PG  G+ G +G++GD+              E+ + G    
Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG----ERGVKGACGL 2636

Query: 2923 FNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGL 2982
              +         +  + + GPPG PG  G  G  GEPG  G+ G PG  G+ GP G+RG 
Sbjct: 2637 DGE---------KGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGF 2687

Query: 2983 PGEKGERG-TGSSGPRGLPGP---PGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037
             G+ G +G  G  G RG PG    PGP G +   GPPG  GS GP GP G  G  G RGP
Sbjct: 2688 DGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGP 2747

Query: 3038 PG 3039
            PG
Sbjct: 2748 PG 2749



 Score =  217 bits (553), Expect = 1e-55
 Identities = 153/423 (36%), Positives = 180/423 (42%), Gaps = 127/423 (30%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP------QGPPG-------- 2792
            G  GP GP G PG  G  GERGI G  GPPGP+GD G  GP      +GPPG        
Sbjct: 1725 GQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLD 1784

Query: 2793 -------PQGPNGLS----------IPGEQGRQGMKGDAGEPGLPGR------------T 2823
                   P GPNG +          +PG +G QG+ G +G PGLPG+             
Sbjct: 1785 GKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKN 1844

Query: 2824 GTPGLPGPPGPMGPPGDRGFTGKDGAMGPR---------GPPGPPGSPGS--------PG 2866
            G PG PG  G  G  GD G +G++G  GP+         GP GPPG PG         PG
Sbjct: 1845 GEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPG 1904

Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGD----------IASQNMMRAVARQVCE--Q 2914
            V G +G  G  G+ G  G  GL GE+G RG+          + +  +  +  R++ E   
Sbjct: 1905 VPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWD 1964

Query: 2915 LISGQMNRFNQMLNQIPND--------------------YQSSRNQPGPPGPP------- 2947
              SG      +       D                     +  R  PGP GPP       
Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGER 2024

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTP---GMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP 3003
            GPPG +G  GEPG  G PG PG     G  G PGERG  GEKGERG  G  GP GLPG P
Sbjct: 2025 GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTP 2084

Query: 3004 GPQG------------------------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPG 3039
            GP G                        +   G PGS G +GP G  G PG  G RG PG
Sbjct: 2085 GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPG 2144

Query: 3040 PPG 3042
            P G
Sbjct: 2145 PRG 2147



 Score =  217 bits (552), Expect = 2e-55
 Identities = 148/378 (39%), Positives = 169/378 (44%), Gaps = 100/378 (26%)

Query: 2747 GPPGPPGPAG-----GPGAKGPRGERGISGAIGPPGPRGDIGPPGP---------QGPPG 2792
            G PGPPGP G     GPGA+  +GE G  G  GP GP+GD G PG          +GPPG
Sbjct: 1697 GEPGPPGPPGRLVDTGPGAR-EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPG 1755

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGK 2846
            PQG      PG +G  G KGD G PGL GR+G  G PG  GP GP       GD G  G 
Sbjct: 1756 PQGD-----PGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL 1810

Query: 2847 DGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRA 2906
             G  G +G PGP G PG PG  G  GKPG  G +G PG  G  G KG++GD  +      
Sbjct: 1811 PGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGA------ 1864

Query: 2907 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPG 2966
                      SG+  R         +  +  R  PG  GP GPPG  G  G PG G    
Sbjct: 1865 ----------SGREGR---------DGPKGERGAPGILGPQGPPGLPGPVGPPGQG---- 1901

Query: 2967 FPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPG---------------------- 3004
            FPG PG  GP G+RG  G KGE+G    G RGL G PG                      
Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGEQGL--PGERGLRGEPGSVPNVDRLLETAGIKASALREI 1959

Query: 3005 ------------PQGESRTGPPGSTGSRGPPG---PPGRPGNSGIRG------PPGPPGY 3043
                        P  E R GP G +G +GPPG   P G PG  G++G      P GPPG 
Sbjct: 1960 VETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL 2019

Query: 3044 CDSSQCASIPYNGQGYPG 3061
                +    P    G PG
Sbjct: 2020 ALGERGPPGPSGLAGEPG 2037



 Score =  215 bits (548), Expect = 5e-55
 Identities = 145/341 (42%), Positives = 161/341 (47%), Gaps = 68/341 (19%)

Query: 2746 VGPPGPPGPAGGPGAK-----GPRGERGISGA-----IGPPGPRGDIGPPGPQGPPGPQG 2795
            VGP G PGP G PG       G +GE+G  G      +G PG +GD G PGP+G  G  G
Sbjct: 2286 VGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG 2345

Query: 2796 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA----- 2849
              G    PGE G++G  G  G  G PG  G PG PGPPGP G  GD G  G  GA     
Sbjct: 2346 RAGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVG 2404

Query: 2850 ----MGPRGPPGPPGS---------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 2896
                 GPRG  G PG          PG  G+ GP G PG PG  G PG SGLKG+KGD G
Sbjct: 2405 FPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG 2464

Query: 2897 -DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGA 2955
              +      R       E  I G+  R                 Q GP G  GPPGS G 
Sbjct: 2465 VGLPGPRGERG------EPGIRGEDGR---------------PGQEGPRGLTGPPGSRGE 2503

Query: 2956 RGEPGPGGRPGFPGTPG----MQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG 3007
            RGE G  G  G  G  G    + GPPG RG  G+ GERG     G  GPRG  G PG +G
Sbjct: 2504 RGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563

Query: 3008 ESRTGPPGSTGSRGPP------GPPGRPGNSGIRGPPGPPG 3042
                G PG  GS G P      GP G+PG +GI G PG PG
Sbjct: 2564 SK--GEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG 2602



 Score =  213 bits (541), Expect = 3e-54
 Identities = 133/323 (41%), Positives = 150/323 (46%), Gaps = 50/323 (15%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQ 2805
            VG  G  GP G PG  G  GERG+ GA   PG RG +G  G QG PG  G NG   PG  
Sbjct: 1636 VGEKGDEGPPGDPGLPGKAGERGLRGA---PGVRGPVGEKGDQGDPGEDGRNG--SPGSS 1690

Query: 2806 GRQGMKGDAGEPGLPGR----------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP 2855
            G +G +G+ G PG PGR           G PG  G  GP GP GD G  G  G  G  G 
Sbjct: 1691 GPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGF 1750

Query: 2856 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915
             GPPG  G PGV GP+G+ G  G  G  G SGL G+ G  G  +  N     A       
Sbjct: 1751 RGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGP-SGPNGAAGKAGDPGRDG 1809

Query: 2916 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG 2975
            + G                +  +  PGP GPPG PG  G  G+PG  G+ G PG PG  G
Sbjct: 1810 LPG---------------LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDG 1854

Query: 2976 PPGER---------GLPGEKGERGT----GSSGPRGLPGPPGPQGE------SRTGPPGS 3016
              GE+         G  G KGERG     G  GP GLPGP GP G+        TGP G 
Sbjct: 1855 RKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGD 1914

Query: 3017 TGSRGPPGPPGRPGNSGIRGPPG 3039
             G  G  G  G PG  G+RG PG
Sbjct: 1915 RGETGSKGEQGLPGERGLRGEPG 1937



 Score =  212 bits (540), Expect = 4e-54
 Identities = 125/321 (38%), Positives = 147/321 (45%), Gaps = 46/321 (14%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G  G PGP+G  G  GP G  GI G +GPPGP G +GPPG  G  G +G  G+ +PG +G
Sbjct: 2413 GEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG 2472

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG-------PPGPP 2859
             +G  G  GE G PG+ G  GL GPPG  G  G++G  G  G  G +G       PPGP 
Sbjct: 2473 ERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR 2532

Query: 2860 GSPGSPGVTGP---SGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLI 2916
            G+ G  G  GP    G  G  GD+G PG  G KGE GD+G      +   +         
Sbjct: 2533 GAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLG-------- 2584

Query: 2917 SGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP 2976
                          P     +   PG PG PG  G  G RGE G  G  G  G  G +G 
Sbjct: 2585 --------------PQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGV 2630

Query: 2977 PGERGLPGEKGERG----------TGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGP 3022
             G  GL GEKG++G           G  G  G PG PG  G    E   GP G  G  G 
Sbjct: 2631 KGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ 2690

Query: 3023 PGPPGRPGNSGIRGPPGPPGY 3043
            PGP G  G  G RG PG  G+
Sbjct: 2691 PGPKGDQGEKGERGTPGIGGF 2711



 Score =  207 bits (527), Expect = 1e-52
 Identities = 133/326 (40%), Positives = 151/326 (46%), Gaps = 65/326 (19%)

Query: 2752 PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMK 2811
            P P    G KG  GE+G  G  GP G  G+ G  G +G PGPQGP GL++ GE+G  G  
Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLAL-GERGPPGPS 2030

Query: 2812 GDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPS 2871
            G AGEPG PG  G PG  G  G  G PG+RG  G+ G  G +G  GPPG PG+PG  GP 
Sbjct: 2031 GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPP 2090

Query: 2872 G------KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925
            G      +PG PG  G  GP GLKG KG+ G                             
Sbjct: 2091 GPKVSVDEPG-PGLSGEQGPPGLKGAKGEPG----------------------------- 2120

Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 2985
                       S    GP G  G PG  G RGEPGP G+ G PG PG +G  G  G PG 
Sbjct: 2121 -----------SNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGL 2169

Query: 2986 KGERGT-GSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNS--------GIR 3035
            +G RG  G  G  G PGPPG  G     GP G +G +G PG  G PG          G+ 
Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP 2229

Query: 3036 GPPGPPGYCDSSQCASIPYNGQGYPG 3061
            GPPGP G          P    G PG
Sbjct: 2230 GPPGPSGLVG-------PQGSPGLPG 2248



 Score =  196 bits (498), Expect = 3e-49
 Identities = 142/413 (34%), Positives = 167/413 (40%), Gaps = 103/413 (24%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI---SGAIGPPGPRGDIGPPGPQG 2789
            P+ PN         G  G PG  G  G  GP G  G+    G  G PG  G  G PG  G
Sbjct: 1792 PSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPG 1851

Query: 2790 PPGPQGPNGLS-IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP-----------PGPMGP 2837
              G +G  G S   G +GR G KG+ G PG+ G  G PGLPGP           PG  GP
Sbjct: 1852 EDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGP 1911

Query: 2838 PGDRGFTGKDGAMGPRGPPGPPGSPGS--------------------------------- 2864
             GDRG TG  G  G  G  G  G PGS                                 
Sbjct: 1912 KGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFL 1971

Query: 2865 ---------PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM---------RA 2906
                      G +G  G PGK G  G PG  GLKG++GD G      +            
Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSG 2031

Query: 2907 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ------------------PGPPGPPG 2948
            +A +  +  I G   R   +        +  R +                  PGPPGPPG
Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091

Query: 2949 P--------PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG---------- 2990
            P        PG +G +G PG  G  G PG+ G QGP G+RG+PG KG+RG          
Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151

Query: 2991 TGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             G  G RG+ GP G  G +   GPPG  G  G PGPPG PG +G  GP GP G
Sbjct: 2152 PGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSG 2204



 Score =  190 bits (482), Expect = 2e-47
 Identities = 124/304 (40%), Positives = 144/304 (47%), Gaps = 56/304 (18%)

Query: 2762 GPRGERGISGAIGPPGPRGDIGPPGPQGPPG--PQGPNGLSIPGEQGRQGMKGDAGEPGL 2819
            GP  ++ +SG             P P+  P   P+G  G   PGE G +G  G  G+PGL
Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGE--PGEMGLRGQVGPPGDPGL 1276

Query: 2820 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD 2879
            PGRTG PG  GPPG     G+RGF G DG  G  G  G PG+PG+PG+ G  G PG  GD
Sbjct: 1277 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD 1336

Query: 2880 HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939
             G  GP G KGE G  G +                               I  +      
Sbjct: 1337 PGERGPRGPKGEPGAPGQV-------------------------------IGGEGPGLPG 1365

Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP--------GMQGPPG--ERGL-PGEKGE 2988
            + G PGP GPPG  G  G+PGP G PG PGT         G +GPPG  E G+ PGE G 
Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425

Query: 2989 RGT-GSSGPRGLPGPPGPQGE---SRTGPPGSTGS------RGPPGPPGRPGNSGIRGPP 3038
             G  GS GP+G  GPPG +GE   S  G PG  G       +GP GPPG  G  G RG P
Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485

Query: 3039 GPPG 3042
            GP G
Sbjct: 1486 GPLG 1489



 Score =  179 bits (455), Expect = 3e-44
 Identities = 110/301 (36%), Positives = 169/301 (56%), Gaps = 23/301 (7%)

Query: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFD--IGEEKTRVGVVQYSSDTRTEFNLNQY 197
           D+VFL+DGS S+GR+NF+ +  F+  LV  F      +  R   VQYS D RTEF L+  
Sbjct: 38  DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 198 YQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEV 257
               +++ AI+++ YKGGNT TG AI ++  + F     AR G PKV I+ITDGKSQD V
Sbjct: 98  GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQL-ARPGVPKVCILITDGKSQDLV 156

Query: 258 EIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVC 317
           +  A+ L+  GV++F++GIK AD +ELK++AS P+ +  F V +F  +  +   +  +VC
Sbjct: 157 DTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVC 216

Query: 318 SGVDEQLGELVSGEEVVEPPS-------NLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
           +           G  V  PP        +L+  E SS+ +++ W  +  PVTGYKV  TP
Sbjct: 217 T--------TAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTP 268

Query: 371 MTA-----GSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425
           +T       S +  ++V    T++ +R L   TEYQ++V A+   +  E +S   +T  +
Sbjct: 269 LTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTAL 328

Query: 426 K 426
           +
Sbjct: 329 E 329



 Score =  178 bits (451), Expect = 8e-44
 Identities = 122/319 (38%), Positives = 144/319 (45%), Gaps = 31/319 (9%)

Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 2799
            DS    GPPGP G  G  G RG RG+ G  GP G  GD G  G +G PG +G  GL    
Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK---------DGAM 2850
             + G QG+ G  G  G+PG PG+ G PG+ G  G +G  G RG  G+         DG  
Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEK 2640

Query: 2851 GPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQ 2910
            G +G  GPPG PG  G  G  G+PG PG  G PG  GL G KGDRG    Q   +    +
Sbjct: 2641 GDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRG-FDGQPGPKGDQGE 2699

Query: 2911 VCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPG---PPGPPGSAGARGEPGPGGR--- 2964
              E+   G +  F       P+    S   PGPPG   P GP G  G +GE GP G    
Sbjct: 2700 KGERGTPG-IGGFPG-----PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVV 2753

Query: 2965 -----PGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019
                 PG PG  G QG PG  G  GEKGE        RG       Q  +  G   ++GS
Sbjct: 2754 GAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGS 2813

Query: 3020 RGPPGPPGRPGNSGIRGPP 3038
            R  P        S +   P
Sbjct: 2814 RPLPSYAADTAGSQLHAVP 2832



 Score =  169 bits (429), Expect = 3e-41
 Identities = 187/765 (24%), Positives = 314/765 (41%), Gaps = 58/765 (7%)

Query: 634  PPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKP 693
            P  DL  +E+     + +WSP       Y I  +   G +  T+V P S T+  L  ++ 
Sbjct: 510  PVTDLQATELPGQRVRVSWSPV-PGATQYRIIVRSTQGVER-TLVLPGSQTAFDLDDVQA 567

Query: 694  ETLYLVNVTAEY--EDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVL 751
               Y V V+A     +G +  L      E     P  L+V        ++ W   PG   
Sbjct: 568  GLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATRVRVAWGPVPG-AS 625

Query: 752  RYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEV--SVIPEYFSGPGTPLTGNAA 809
             +RI +   +G ES + T PP+     +  L P T Y+V  SV+     GP   +    A
Sbjct: 626  GFRISWSTGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIV---A 681

Query: 810  TEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTV 869
              +  G  R + V+  ++S++ ++W+  PG    Y V++    G E  ++ V G+ T   
Sbjct: 682  RTDPLGPVRTVHVTQASSSSVTITWTRVPGATG-YRVSWHSAHGPEKSQL-VSGEATVAE 739

Query: 870  LQGLKEGTQYALSVTALYASGAGD-ALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
            L GL+  T+Y + V A  A   G  A     T  E  G    L   + +   +   W   
Sbjct: 740  LDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGV 799

Query: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
             G    YR++W    +      + LP +     I  L+    Y + V A     EG P++
Sbjct: 800  TGAT-AYRLAW-GRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVS 857

Query: 989  GDATT--ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046
               TT  E      TL V +  E+++R+ W+P P +   + + ++P G G++    + P 
Sbjct: 858  IVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVP-RAQGFLLHWQPEG-GQEQSRVLGPE 915

Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPR----NLKTSDPTMSS 1102
            ++S  L  L+P T Y + +  +   GEG     S    +R +SPR     L+  D ++ S
Sbjct: 916  LSSYHLDGLEPATQYRVRLSVLGPAGEGP----SAEVTARTESPRVPSIELRVVDTSIDS 971

Query: 1103 FRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP------YDNTVVLEELRAGTTYKVN 1156
              + W P       Y +++ P    R  G+ V G         ++  +  L  G +Y  +
Sbjct: 972  VTLAWTPV-SRASSYILSWRPL---RGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFS 1027

Query: 1157 VFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFR 1216
            +  + DG      V     +++ T V P          R  AD+V L   +         
Sbjct: 1028 LTPVLDG------VRGPEASVTQTPVCP----------RGLADVVFLPHATQDNAHRAEA 1071

Query: 1217 TVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPY--KGG 1274
            T R     ++ +  +GP+ VQ+ L  YS  P   + LN   D   +LQ + ++PY    G
Sbjct: 1072 TRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSG 1131

Query: 1275 NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIG 1334
            N L    +   R        G R     + VL+ D   + D+ +P ++ +  G+ +  +G
Sbjct: 1132 NNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLG 1191

Query: 1335 IKNADEVELKMIATDPDDTHA-YNVADFESLSRIVDDLTINLCNS 1378
            +  AD  +L+ +A   D     + V D  SL + V  L   LC +
Sbjct: 1192 MAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALCQA 1236



 Score =  120 bits (300), Expect = 3e-26
 Identities = 70/184 (38%), Positives = 104/184 (56%), Gaps = 2/184 (1%)

Query: 2322 ADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPA-GIQVSFVQYSDEVKSEFKLNT 2380
            ADIVFL D S SIG  NF +V  F+   V  F   + A G++ + VQYSD+ ++EF L+ 
Sbjct: 37   ADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDA 96

Query: 2381 YNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDE 2440
                   + A++ + Y+GGNTRTG A+  + + V   +   R  VPKV +++TDG+SQD 
Sbjct: 97   LGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA-RPGVPKVCILITDGKSQDL 155

Query: 2441 VKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFV 2500
            V  AA  ++  G  +F VG+ + D  EL  +AS+P+    F V+DF     +   +   V
Sbjct: 156  VDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRV 215

Query: 2501 CETA 2504
            C TA
Sbjct: 216  CTTA 219



 Score =  108 bits (269), Expect = 1e-22
 Identities = 73/200 (36%), Positives = 83/200 (41%), Gaps = 51/200 (25%)

Query: 2878 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSS 2937
            G  G PG  GL+G+ G  GD                                +P      
Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPG------------------------------LPG----- 1278

Query: 2938 RNQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPGTPGMQGPPGERGLPGEKGE 2988
              + G PGP GPPGSA A+GE         PG  GR G PGTPG  G  G  GLPG +G+
Sbjct: 1279 --RTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD 1336

Query: 2989 RGT-GSSGPRGLPGPPGP----QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043
             G  G  GP+G PG PG     +G    G  G  G  GPPGP G  G+ G RGPPG PG 
Sbjct: 1337 PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396

Query: 3044 CDSSQCASIPYNGQGYPGSG 3063
                        G   PG G
Sbjct: 1397 AMKGDKGDRGERGPPGPGEG 1416



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 44/105 (41%), Positives = 51/105 (48%), Gaps = 12/105 (11%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802
            Q   G  G PG  G PG  G        G+ GPPGP G +GP GP+G  G +G  G   P
Sbjct: 2697 QGEKGERGTPGIGGFPGPSGN------DGSAGPPGPPGSVGPRGPEGLQGQKGERG--PP 2748

Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 2847
            GE+    + G  G PG PG  G  G PGP GP G  G+   T  D
Sbjct: 2749 GER----VVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDD 2789



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 50/179 (27%), Positives = 73/179 (40%), Gaps = 7/179 (3%)

Query: 2119 PQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPV-GSNEPMEAFVGEM------TSYTL 2171
            P+++ +S+      RV W  +  PV GYK+ Y P+ G  +P+ +   E+      TS  L
Sbjct: 235  PRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRL 294

Query: 2172 HNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAAT 2231
              L P T Y V V A Y + +   ++    T  L   +L        +  V W     AT
Sbjct: 295  RGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGAT 354

Query: 2232 SYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHT 2290
             YR+      G   Q+  +   + S     L P TDY VTV        GP  S+   T
Sbjct: 355  GYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMART 413



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 68/291 (23%), Positives = 112/291 (38%), Gaps = 23/291 (7%)

Query: 336  PPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT-----TTLS 390
            P   L  ++ S   V L W P  S  + Y +   P+    ++  +   PQT     ++  
Sbjct: 958  PSIELRVVDTSIDSVTLAWTPV-SRASSYILSWRPLRGPGQE--VPGSPQTLPGISSSQR 1014

Query: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
            V  L     Y  S++ +         S+ +          C RG+   AD+VFL   +  
Sbjct: 1015 VTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPV-------CPRGL---ADVVFLPHATQD 1064

Query: 451  IGIANFVKVRAFLEVLVKSF-EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINT 509
                     R  LE LV +   + P  VQ+ L+ YS  P   F L     +  I++ I  
Sbjct: 1065 -NAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRD 1123

Query: 510  FPYRGGS-TNTGKAMTYVREKIFVP-SKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNS 567
             PY   S  N G A+      +  P + G R +VP VM+L+ D         P  + + S
Sbjct: 1124 MPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQAS 1183

Query: 568  DVEIFAVGVKDAVRSELEAIASPPAETHV-FTVEDFDAFQRISFELTQSIC 617
             + +  +G+  A   +L  +A         F V+D  +  +    L  ++C
Sbjct: 1184 GLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALC 1234



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 38/151 (25%), Positives = 71/151 (47%), Gaps = 9/151 (5%)

Query: 172  IGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYK--GGNTMTGDAIDYLVKN 229
            +G +  +VG++ YS      F LN  +    +L  I+ +PY    GN +    +      
Sbjct: 1086 LGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYM 1145

Query: 230  TFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIAS 289
               ++ G R   P V +++ D   + ++  P RE +  G+ V  LG+  AD ++L+++A 
Sbjct: 1146 LAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLA- 1204

Query: 290  TPSLNHVFNVANFDAIVDIQNEIISQVCSGV 320
             P ++   +V  F A+ D     + Q  SG+
Sbjct: 1205 -PGMD---SVQTFFAVDD--GPSLDQAVSGL 1229



 Score = 41.6 bits (96), Expect = 0.012
 Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 6/102 (5%)

Query: 324 LGELVSGEE---VVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHAL 380
           +GE VSG      +E P  L     ++  + + W   P   TGY+V    ++ G  Q   
Sbjct: 315 IGEAVSGTARTTALEGPE-LTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQ- 371

Query: 381 SVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            +GP   ++ +RDL   T+Y+++VS + G +     S+M +T
Sbjct: 372 ELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMART 413



 Score = 37.4 bits (85), Expect = 0.23
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 4/109 (3%)

Query: 318 SGVDEQLGELV--SGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGS 375
           +GVD     +V  +  E V   S L  +  SS  +++ W    +  T Y++       G 
Sbjct: 758 AGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITW-VGVTGATAYRLAWGRSEGGP 816

Query: 376 RQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQP 424
            +H +  G  T +  +R L     Y + V+A+ G     P+SI+  T P
Sbjct: 817 MRHQILPG-NTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPP 864



 Score = 37.0 bits (84), Expect = 0.30
 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 3/76 (3%)

Query: 350 VKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKG 409
           V++ W P P   +G+++  +  T    + + ++ P +T   +  L   T YQ++VS ++G
Sbjct: 614 VRVAWGPVPG-ASGFRISWS--TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670

Query: 410 MTSSEPISIMEKTQPM 425
                   I+ +T P+
Sbjct: 671 REEGPAAVIVARTDPL 686



 Score = 36.6 bits (83), Expect = 0.39
 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 3/91 (3%)

Query: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
           V P ++L A E+  + V+++W+P P   T Y++I+   T G  +  +  G Q T   + D
Sbjct: 508 VSPVTDLQATELPGQRVRVSWSPVPG-ATQYRIIVR-STQGVERTLVLPGSQ-TAFDLDD 564

Query: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQP 424
           + A   Y + VSA  G        +  + +P
Sbjct: 565 VQAGLSYTVRVSARVGPREGSASVLTVRREP 595



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 4/64 (6%)

Query: 36  IDENTVH---MSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVV 92
           I   T H   ++W + V    GYR+T    + GPT++  L       LL +L P T+Y V
Sbjct: 335 IQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEV 393

Query: 93  TITS 96
           T+++
Sbjct: 394 TVST 397



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 3/101 (2%)

Query: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
           +V+  + + P   +   + SS  V + W   P   TGY+V  +  +A   + +  V  + 
Sbjct: 679 IVARTDPLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRV--SWHSAHGPEKSQLVSGEA 735

Query: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKV 427
           T   +  L  DTEY + V A        P S++ +T P  V
Sbjct: 736 TVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPV 776



 Score = 33.9 bits (76), Expect = 2.5
 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 6/73 (8%)

Query: 28  PSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT------DGPTKEFTLSASTTETLL 81
           P DL        ++ + W     P+ GY++   P T          +E  + A  T   L
Sbjct: 235 PRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRL 294

Query: 82  SELVPETEYVVTI 94
             L P TEY VT+
Sbjct: 295 RGLRPLTEYQVTV 307


>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
          Length = 2296

 Score =  342 bits (877), Expect = 3e-93
 Identities = 370/1525 (24%), Positives = 602/1525 (39%), Gaps = 154/1525 (10%)

Query: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746

Query: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035

Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093

Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136

Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179

Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239

Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504
              EY V+VY+V +D+ S P+  T      P   L   ++GP TM V W P      T ++
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299

Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
            + Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V     S P+  R+ T 
Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356

Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621
             L  P  +   D+T ++  V W      +  Y +R+  PE      +E  V  S  S +L
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415

Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
             +L   T Y VS+ A++   ESP +  Q++T     P +L++   T      +WD  A  
Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474

Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
            V  YRIT+   G +S   E  + G ++T     L P   Y +++ A+    +   D   S
Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530

Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
             + + I   T+  K  P  +QV +   NS++VKW P+S  V  YR+T  P  G G  +T 
Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588

Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859
            T G  Q  + ++ L+P   Y ++V +  P GE   +     T  +    +L+    + ++
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTS 1647

Query: 1860 LNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 1918
            L+ +W         Y++   P    GP + + +  +++  ++  L   T Y V+V  +  
Sbjct: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707

Query: 1919 EGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 1977
                        TL      R  +V + T  ++ + W      +  ++V   P +G  P 
Sbjct: 1708 TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI 1767

Query: 1978 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 2037
            +  + P + R   +  L P T Y + L  L  +   +P      T     P NLR    T
Sbjct: 1768 QRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATT 1825

Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV---ILQPLQPDTPYKIT 2094
             NSL V+W      +  Y I Y      P +    VP  R  V    +  L+P T Y I 
Sbjct: 1826 PNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVTEATITGLEPGTEYTIY 1882

Query: 2095 VIAVYEDGDGGHLTGNGRTVGL-----LPPQNIH---ISDEWYTRFRVSWDPSPSPVLGY 2146
            VIA+  +     L G  +T  L     LP  N+H   I D   T  +  +   P    G 
Sbjct: 1883 VIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGN 1942

Query: 2147 KIVYKPVGSNEPMEAFVGEMTSYTLHNL---NPSTT----------YDVNVYAQYDSGLS 2193
             I        +P    VG+   +  H      P TT          Y  NV  +   G  
Sbjct: 1943 GIQLPGTSGQQPS---VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIG-H 1998

Query: 2194 VPLTDQGTTLYLNVTDL----KTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEIT 2249
            +P  D    LY +   L     T Q       + W+P +  + Y +   P  GT  + + 
Sbjct: 1999 IPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQ 2057

Query: 2250 VR--GSETSHCFTGLSPDTDYGVTV 2272
             R  G+ TS   TGL+    Y + V
Sbjct: 2058 FRVPGTSTSATLTGLTRGATYNIIV 2082



 Score =  288 bits (737), Expect = 6e-77
 Identities = 295/1234 (23%), Positives = 501/1234 (40%), Gaps = 84/1234 (6%)

Query: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786

Query: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844

Query: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904

Query: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963

Query: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079

Query: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136

Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195

Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255

Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225
            S P+    +  +   T +   + G + +    A          SI   NF    S +   
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308

Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280
             +V ++       A+   +  P TE+ ++      S+ +   + P +G      ++ TG+
Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364

Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340
              + I   +F T   + PRA   G  I              ++      +    +    E
Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423

Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400
              + ++A +  +     +    ++S                    + P +L +   T  S
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463

Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458
              +SW  P+ +V  Y++ Y    G    QEF V   +++  +  LKP  +Y + VY+V  
Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523

Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514
                   S+P+    +T       + + DV   ++ V+W P     TGY ++  P     
Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583

Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
            PT+ K    GP   +M +  L P  EY V+V A      S+P+    VT  +P P DLK 
Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKF 1640

Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSLKDLFSQTLYT 1631
              VT ++++  W P   ++  Y VR  TP+E    +KE+ +    +S  +  L   T Y 
Sbjct: 1641 TQVTPTSLSAQWTPPNVQLTGYRVRV-TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699

Query: 1632 VSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWA 1690
            VSV A+ D   S P     TT   V  P   ++T+ T      +W      ++ +++   
Sbjct: 1700 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1759

Query: 1691 PFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQ 1750
            P      ++  +  D  +     L P T Y++ +  +  +   S  +I +   +      
Sbjct: 1760 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI------ 1813

Query: 1751 APKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVL 1810
                 P NL+    T NSL V W P   R+  Y I Y+       E             +
Sbjct: 1814 ---DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870

Query: 1811 QKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 1844
              L+P T YTI V +L  + +   + GR KT  L
Sbjct: 1871 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904



 Score =  281 bits (719), Expect = 7e-75
 Identities = 240/929 (25%), Positives = 404/929 (43%), Gaps = 39/929 (4%)

Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056

Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114

Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170

Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230

Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288

Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347

Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399

Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458

Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578

Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P +
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637

Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 2089
            L+    T  SLS  W   +  +  YR+  +P     P+ E    P   ++V++  L   T
Sbjct: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696

Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 2148
             Y+++V A+ +        G   T+  + PP+   ++D   T   +SW      + G+++
Sbjct: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756

Query: 2149 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207
               P     P++  +  ++ SYT+  L P T Y + +Y   D+  S P+    +T     
Sbjct: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816

Query: 2208 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 2265
            ++L+      ++  V W P RA  T Y +K   P    R      R   T    TGL P 
Sbjct: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876

Query: 2266 TDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
            T+Y + V     N +   +  ++ T   P
Sbjct: 1877 TEYTIYVIALKNNQKSEPLIGRKKTDELP 1905



 Score =  262 bits (670), Expect = 3e-69
 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%)

Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871

Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931

Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045

Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105

Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158

Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213

Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272

Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332

Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391

Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450

Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509

Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568

Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 2258
             T     TDLK  Q+   +   +W+P     T YR++++P + T   +EI +    +S  
Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688

Query: 2259 FTGLSPDTDYGVTVF 2273
             +GL   T Y V+V+
Sbjct: 1689 VSGLMVATKYEVSVY 1703



 Score =  213 bits (543), Expect = 2e-54
 Identities = 155/567 (27%), Positives = 252/567 (44%), Gaps = 17/567 (2%)

Query: 631  AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688
            A  PP DL F+ +     +  W+P    ++ ++ + Y     +++V  +  + S  +VVL
Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325

Query: 689  SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748
            ++L P T Y+V+V++ YE   S PL G + T     +P  +  +D T +SF + W     
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383

Query: 749  RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807
             +  YRI + P    G  RE   P ++   TL NL P T+Y VS++          L G 
Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443

Query: 808  AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866
             +T  V   PRDL V   T +++ +SW      V+ Y +TY    G    QE TV G  +
Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501

Query: 867  NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922
               + GLK G  Y ++V A+  +G GD+             E   P  +   D+ D SI 
Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 923  AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982
              W  +   V GYRV+         T  K    D     IE LQP  +Y +SV+A   SG
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 983  EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGR-GKQMVA 1041
            E +PL   A T +   +  LK  + T  ++   W P   ++  YRV   P  + G     
Sbjct: 1620 ESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678

Query: 1042 KVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101
             + P  +S V+  L   T Y+++V  +      +  QG  TT      PR  + +D T +
Sbjct: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738

Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161
            +  ++W      + G++V   P      + +  + P   +  +  L+ GT YK+ ++ + 
Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797

Query: 1162 DGGESSPLVGQEMTTLSDTTVMPILSS 1188
            D   SSP+V    T +   + +  L++
Sbjct: 1798 DNARSSPVVIDASTAIDAPSNLRFLAT 1824



 Score =  200 bits (508), Expect = 2e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679

Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738

Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798

Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858

Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912

Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972

Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031

Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089

Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142

Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257

Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316

Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376

Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436

Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304
             P + + + +TV   P +      TP
Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461



 Score =  192 bits (487), Expect = 6e-48
 Identities = 294/1314 (22%), Positives = 508/1314 (38%), Gaps = 144/1314 (10%)

Query: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963

Query: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104

Query: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164

Query: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
              A  +S    +L P   Y V+V    +D  S+P++  +T       P +L+ T+   D+
Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282

Query: 739  FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796
             ++TW   P   +  + + Y PV   E   E++  P+     L NL+P T+Y VSV   Y
Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342

Query: 797  FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855
                 TPL G   T     +P  +  SD T ++  + W      +  Y + + P    G 
Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400

Query: 856  TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915
             +E  V     +  L  L  GT+Y +S+ AL        L G+ +T+ +   P+DL    
Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458

Query: 916  ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975
             T TS+   W +    VR YR+++     +    E  +P       I  L+P   Y I+V
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 976  FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
            +A    G+     +P++ +  TE+ + S+ ++V +  +N++ V W P+   V  YRV   
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089
            P +G G        P  T   ++ LQP   Y ++V      GE + L Q + TT     +
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA 1634

Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149
            P +LK +  T +S    W P   ++ GY+V   P      + E+ + P  ++VV+  L  
Sbjct: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694

Query: 1150 GTTYKVNVFGMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRA 1196
             T Y+V+V+ + D   S P  G               +T  ++TT+     +  E +T  
Sbjct: 1695 ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGF 1754

Query: 1197 EADIVLLVDGSWSIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNA 1255
            + D V   +G   I R     VRS+ I+ +    D   K     L   +         + 
Sbjct: 1755 QVDAV-PANGQTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDAST 1811

Query: 1256 HRDKKSLLQAVANLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLIT 1308
              D  S L+ +A  P             +TG  + + +  +   +   RPR       IT
Sbjct: 1812 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 1871

Query: 1309 DGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIV 1368
              +   +       LK+       IG K  DE+  +++     + H   + D  S  +  
Sbjct: 1872 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKT 1930

Query: 1369 DDLT---INLCNSVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYP 1421
              +T    +  N ++ PG   + PS    ++  E     FR +  P + +  R++   YP
Sbjct: 1931 PFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYP 1987

Query: 1422 VSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLN 1481
             + G  +E  +  +    V   L P    +    S  ++  S+                 
Sbjct: 1988 PNVG--EEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQ----------------- 2028

Query: 1482 IYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEY 1541
                  TT  + W P    + YI+S  PV   E   P + R+  T     LT L     Y
Sbjct: 2029 ------TT--ISWAPFQDTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATY 2078

Query: 1542 AVTVQAV----LHDLTSEPVTV-REVTLPLPRPQDLKLRD---VTHSTMNVFWE 1587
             + V+A+     H +  E VTV   V   L +P D    D   V+H  +   WE
Sbjct: 2079 NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2132



 Score =  161 bits (407), Expect = 1e-38
 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)

Query: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944

Query: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002

Query: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062

Query: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119

Query: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176

Query: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232

Query: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020
              +NL P  +Y +SV+      E  P++ D           L+      +TMRVTW P P
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291

Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
               + N+ V Y P  + ++ VA+  + P+  + VL  L P T Y ++V  +Y+  E    
Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350

Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
            +G   T     SP  +  SD T +SF V W      + GY++  HP     R  E  V  
Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408

Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179
              N++ L  L  GT Y V++  + +G E SPL+  + +T+SD
Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449



 Score =  155 bits (391), Expect = 8e-37
 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%)

Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695

Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755

Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815

Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875

Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935

Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993

Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052

Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107

Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D         
Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246
            + +  PL+   T L+L    D     + W+      S     T YR+  +P +G +G   
Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221

Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306
            E  V   ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270



 Score =  147 bits (370), Expect = 2e-34
 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)

Query: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917

Query: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977

Query: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035

Query: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148

Query: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266

Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
               P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P DN VVL 
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
             L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362



 Score = 66.6 bits (161), Expect = 4e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859

Query: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916

Query: 134 SVS 136
            V+
Sbjct: 917 EVT 919



 Score = 65.5 bits (158), Expect = 8e-10
 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 7/118 (5%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600

Query: 83   ELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSA-WT 139
             L P  EYVV++ + +   ES P+     +QT  +T P       T++   S+SA WT
Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82
            V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    +L+
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 83   ELVPETEYVVTITSYDEVEESVPVIGQ 109
             L+P TEYVV+++S  E  ES P+ G+
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 1624 LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683

Query: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1719



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849

Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223

Query: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 25/99 (25%), Positives = 45/99 (45%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            ++     ++ PSNL  +  +   + ++W P  + +TGY +      +  R+      P  
Sbjct: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1865

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425
            T  ++  L   TEY I V A+K    SEP+   +KT  +
Sbjct: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 1904



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498

Query: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542

Query: 131  QKCSVSAWTDL 141
             K S    TD+
Sbjct: 1543 DKPSQMQVTDV 1553



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 1813 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1872

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEY + + +    ++S P+IG+
Sbjct: 1873 LEPGTEYTIYVIALKNNQKSEPLIGR 1898



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 1705 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1763

Query: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1806



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            +V+  E V PP      + +   + ++W      +TG++V   P   G      ++ P  
Sbjct: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1775

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446
             + ++  L   T+Y+I +  +     S P           V ++ S  +D  +++ FL  
Sbjct: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1824

Query: 447  GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494
               S+ + ++   RA +   +  +E  P      +V   R   TE T+
Sbjct: 1825 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1870



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797

Query: 102 ESVPVIGQLTIQTGSSTKP 120
           E       L + T  +T P
Sbjct: 798 EQ-----SLILSTSQTTAP 811



 Score = 32.7 bits (73), Expect = 5.7
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)

Query: 312  IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
            ++S V     E+   L+  +  V + P +L  +  +   + ++W+     V  Y++    
Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484

Query: 371  MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423
                S     +V    +T ++  L    +Y I+V A+ G      SS+PISI  +T+   
Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544

Query: 424  PMKVQV 429
            P ++QV
Sbjct: 1545 PSQMQV 1550


>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
          Length = 2176

 Score =  342 bits (876), Expect = 4e-93
 Identities = 349/1417 (24%), Positives = 571/1417 (40%), Gaps = 136/1417 (9%)

Query: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746

Query: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035

Query: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093

Query: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136

Query: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179

Query: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239

Query: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504
              EY V+VY+V +D+ S P+  T      P   L   ++GP TM V W P      T ++
Sbjct: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299

Query: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
            + Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V     S P+  R+ T 
Sbjct: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356

Query: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621
             L  P  +   D+T ++  V W      +  Y +R+  PE      +E  V  S  S +L
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415

Query: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
             +L   T Y VS+ A++   ESP +  Q++T     P +L++   T      +WD  A  
Sbjct: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474

Query: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
            V  YRIT+   G +S   E  + G ++T     L P   Y +++ A+    +   D   S
Sbjct: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530

Query: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
             + + I   T+  K  P  +QV +   NS++VKW P+S  V  YR+T  P  G G  +T 
Sbjct: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588

Query: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859
            T G  Q  + ++ L+P   Y ++V +  P GE   +     T  +    +L+    + ++
Sbjct: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKFTQVTPTS 1647

Query: 1860 LNVRWDHAEGNPRQYKLFYAP-AAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYT 1918
            L+ +W         Y++   P    GP + + +  +++  ++  L   T Y V+V  +  
Sbjct: 1648 LSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1707

Query: 1919 EGDGGRTSDTGRTLMR-GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPS 1977
                        TL      R  +V + T  ++ + W      +  ++V   P +G  P 
Sbjct: 1708 TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI 1767

Query: 1978 ESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGET 2037
            +  + P + R   +  L P T Y + L  L  +   +P      T     P NLR    T
Sbjct: 1768 QRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATT 1825

Query: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNV---ILQPLQPDTPYKIT 2094
             NSL V+W      +  Y I Y      P +    VP  R  V    +  L+P T Y I 
Sbjct: 1826 PNSLLVSWQPPRARITGYIIKYEKPGSPPRE---VVPRPRPGVTEATITGLEPGTEYTIY 1882

Query: 2095 VIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG 2154
            VIA+  +     L G  +T             E  ++  +SW P       Y I   PVG
Sbjct: 1883 VIALKNNQKSEPLIGRKKT-----------GQEALSQTTISWAPF-QDTSEYIISCHPVG 1930

Query: 2155 SN-EPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYD 2189
            ++ EP++  V G  TS TL  L    TY++ V A  D
Sbjct: 1931 TDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 1967



 Score =  290 bits (741), Expect = 2e-77
 Identities = 307/1304 (23%), Positives = 523/1304 (40%), Gaps = 97/1304 (7%)

Query: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786

Query: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844

Query: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904

Query: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963

Query: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079

Query: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136

Query: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195

Query: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255

Query: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225
            S P+    +  +   T +   + G + +    A          SI   NF    S +   
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308

Query: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280
             +V ++       A+   +  P TE+ ++      S+ +   + P +G      ++ TG+
Sbjct: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364

Query: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340
              + I   +F T   + PRA   G  I              ++      +    +    E
Sbjct: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423

Query: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400
              + ++A +  +     +    ++S                    + P +L +   T  S
Sbjct: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463

Query: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458
              +SW  P+ +V  Y++ Y    G    QEF V   +++  +  LKP  +Y + VY+V  
Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523

Query: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514
                   S+P+    +T       + + DV   ++ V+W P     TGY ++  P     
Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583

Query: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
            PT+ K    GP   +M +  L P  EY V+V A      S+P+    VT  +P P DLK 
Sbjct: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-TIPAPTDLKF 1640

Query: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSLKDLFSQTLYT 1631
              VT ++++  W P   ++  Y VR  TP+E    +KE+ +    +S  +  L   T Y 
Sbjct: 1641 TQVTPTSLSAQWTPPNVQLTGYRVRV-TPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1699

Query: 1632 VSVSAVHDEGESPPVTAQETT-RPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWA 1690
            VSV A+ D   S P     TT   V  P   ++T+ T      +W      ++ +++   
Sbjct: 1700 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1759

Query: 1691 PFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQ 1750
            P      ++  +  D  +     L P T Y++ +  +  +   S  +I +   +      
Sbjct: 1760 PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI------ 1813

Query: 1751 APKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVL 1810
                 P NL+    T NSL V W P   R+  Y I Y+       E             +
Sbjct: 1814 ---DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1870

Query: 1811 QKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGN 1870
              L+P T YTI V +L  + +   + GR KT              + S   + W   + +
Sbjct: 1871 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTG-----------QEALSQTTISWAPFQ-D 1918

Query: 1871 PRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDTSYTVTV 1913
              +Y +   P     E L   +PG +  A L  L    +Y + V
Sbjct: 1919 TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 1962



 Score =  281 bits (718), Expect = 9e-75
 Identities = 238/913 (26%), Positives = 398/913 (43%), Gaps = 39/913 (4%)

Query: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056

Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114

Query: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170

Query: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230

Query: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288

Query: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347

Query: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399

Query: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458

Query: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578

Query: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P +
Sbjct: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTTIPAPTD 1637

Query: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSP-TVGDPIDEYTTVPGRRNNVILQPLQPDT 2089
            L+    T  SLS  W   +  +  YR+  +P     P+ E    P   ++V++  L   T
Sbjct: 1638 LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD-SSSVVVSGLMVAT 1696

Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKI 2148
             Y+++V A+ +        G   T+  + PP+   ++D   T   +SW      + G+++
Sbjct: 1697 KYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQV 1756

Query: 2149 VYKPVGSNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207
               P     P++  +  ++ SYT+  L P T Y + +Y   D+  S P+    +T     
Sbjct: 1757 DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP 1816

Query: 2208 TDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTGLSPD 2265
            ++L+      ++  V W P RA  T Y +K   P    R      R   T    TGL P 
Sbjct: 1817 SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 1876

Query: 2266 TDYGVTVFVQTPN 2278
            T+Y + V     N
Sbjct: 1877 TEYTIYVIALKNN 1889



 Score =  273 bits (698), Expect = 2e-72
 Identities = 240/929 (25%), Positives = 400/929 (43%), Gaps = 47/929 (5%)

Query: 1387 APSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS--GGKRQEFYVSRMETSTVLKDL 1444
            +P +L   E T     + WTPP  +V  Y+V+  PV+  G   Q   +SR  T   +  L
Sbjct: 909  SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGL 967

Query: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TGY 1503
             P   Y   V++V     S+PL   + T      +L   +   +T+ V+W P     TGY
Sbjct: 968  SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGY 1027

Query: 1504 ILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVT 1563
             L+   V  T   +P++  +GP+V+   L +L P +EY V++ A+  +  S   T    T
Sbjct: 1028 RLT---VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084

Query: 1564 LPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKD 1623
            L           +VT +T+ + W P P    K  VR     E  +EV  D      S   
Sbjct: 1085 LQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLT 1144

Query: 1624 LFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEG-FRGTWDHGAS-D 1681
               + +YT+ V     E ++P V    T  P+  PTNL +      G    +W+   + D
Sbjct: 1145 PGVEYVYTIQVLRDGQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPD 1202

Query: 1682 VSLYRITWAPFGSS--DKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIG 1739
            ++ YRIT  P      + +E +++ D+++  F+NL+P   Y VS+  +  D+        
Sbjct: 1203 ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE------- 1255

Query: 1740 SERTLPILTTQAPK-SGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGEGNEQ 1797
               ++PI  T  P    P +L+  N   +++ V W  P S  +  + + Y P   E +  
Sbjct: 1256 ---SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312

Query: 1798 TTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPST 1857
              +I    N+VVL  L P T Y ++VSS+Y   E   + GR KT  L++   +   D + 
Sbjct: 1313 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITA 1371

Query: 1858 STLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVP 1915
            ++  V W         Y++ + P   +G P E   +P + N   L NL P T Y V++V 
Sbjct: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVVSIVA 1430

Query: 1916 VYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTR 1975
            +    +         T+   + R+++V   TP SL + WD     V  YR+ Y    G  
Sbjct: 1431 LNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNS 1489

Query: 1976 PSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS------GPR 2029
            P +   VPG+     +  L P   Y++ + A+   G+   SPA  + +  +       P 
Sbjct: 1490 PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINYRTEIDKPS 1546

Query: 2030 NLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDT 2089
             ++V     NS+SV W  +  PV  YR+  +P  G    +  T    +  + ++ LQP  
Sbjct: 1547 QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1606

Query: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149
             Y ++V A    G+   L     T  +  P ++  +    T     W P    + GY++ 
Sbjct: 1607 EYVVSVYAQNPSGESQPLVQTAVTT-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1665

Query: 2150 YKPVGSNEPMEAF--VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207
              P     PM+      + +S  +  L  +T Y+V+VYA  D+  S P     TTL  NV
Sbjct: 1666 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1724

Query: 2208 TDLKTYQIG---WDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263
            +  +  ++      T  + W +     T +++   PA+G    + T++    S+  TGL 
Sbjct: 1725 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1784

Query: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292
            P TDY + ++    N     V +   T +
Sbjct: 1785 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1813



 Score =  262 bits (670), Expect = 3e-69
 Identities = 250/915 (27%), Positives = 390/915 (42%), Gaps = 50/915 (5%)

Query: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871

Query: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931

Query: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986

Query: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045

Query: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105

Query: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158

Query: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213

Query: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272

Query: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332

Query: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391

Query: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450

Query: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509

Query: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568

Query: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 2201 TTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSHC 2258
             T     TDLK  Q+   +   +W+P     T YR++++P + T   +EI +    +S  
Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688

Query: 2259 FTGLSPDTDYGVTVF 2273
             +GL   T Y V+V+
Sbjct: 1689 VSGLMVATKYEVSVY 1703



 Score =  260 bits (665), Expect = 1e-68
 Identities = 246/918 (26%), Positives = 400/918 (43%), Gaps = 69/918 (7%)

Query: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441
            PG    P N  ++E T     ++WTP       +K+   P  GG+     V+    S V+
Sbjct: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140

Query: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496
              L P  EYV  +  V+ D  E   P+     T   P  +L++    D G  T+  +   
Sbjct: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556
                TGY ++  P    +    +EV +    +     +L P  EY V+V  V  D  S P
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258

Query: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612
            ++  +  +P +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +
Sbjct: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316

Query: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672
              S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F 
Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375

Query: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731
              W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E
Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435

Query: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791
             ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + 
Sbjct: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486

Query: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846
            G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP++      
Sbjct: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541

Query: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902
                  ++V D   ++++V+W  +      Y++   P  G GP +      +     +  
Sbjct: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601

Query: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960
            LQP   Y   VV VY +   G +    +T +  +    +++    TP SL  +W P    
Sbjct: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1658

Query: 1961 VLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQG 2020
            +  YRV  +P + T P + I +  ++  V +  L+  T Y V++ AL       P+    
Sbjct: 1659 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1718

Query: 2021 RTLPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNN 2079
             TL   S PR  RV   T  +++++W      +  +++   P  G    + T  P  R+ 
Sbjct: 1719 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1778

Query: 2080 VILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPS 2139
             I   LQP T YKI +  + ++     +  +  T  +  P N+           VSW P 
Sbjct: 1779 TITG-LQPGTDYKIYLYTLNDNARSSPVVIDASTA-IDAPSNLRFLATTPNSLLVSWQPP 1836

Query: 2140 PSPVLGYKIVYKPVGSNEPMEAFVGE---MTSYTLHNLNPSTTYDVNVYAQYDSGLSVPL 2196
             + + GY I Y+  GS  P E        +T  T+  L P T Y + V A  ++  S PL
Sbjct: 1837 RARITGYIIKYEKPGS-PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895

Query: 2197 TDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVR--GSE 2254
                      +   KT Q       + W+P +  + Y +   P  GT  + +  R  G+ 
Sbjct: 1896 ----------IGRKKTGQEALSQTTISWAPFQDTSEYIISCHPV-GTDEEPLQFRVPGTS 1944

Query: 2255 TSHCFTGLSPDTDYGVTV 2272
            TS   TGL+    Y + V
Sbjct: 1945 TSATLTGLTRGATYNIIV 1962



 Score =  213 bits (543), Expect = 2e-54
 Identities = 155/567 (27%), Positives = 252/567 (44%), Gaps = 17/567 (2%)

Query: 631  AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688
            A  PP DL F+ +     +  W+P    ++ ++ + Y     +++V  +  + S  +VVL
Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325

Query: 689  SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748
            ++L P T Y+V+V++ YE   S PL G + T     +P  +  +D T +SF + W     
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383

Query: 749  RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807
             +  YRI + P    G  RE   P ++   TL NL P T+Y VS++          L G 
Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443

Query: 808  AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866
             +T  V   PRDL V   T +++ +SW      V+ Y +TY    G    QE TV G  +
Sbjct: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501

Query: 867  NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922
               + GLK G  Y ++V A+  +G GD+             E   P  +   D+ D SI 
Sbjct: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 923  AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982
              W  +   V GYRV+         T  K    D     IE LQP  +Y +SV+A   SG
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 983  EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGR-GKQMVA 1041
            E +PL   A T +   +  LK  + T  ++   W P   ++  YRV   P  + G     
Sbjct: 1620 ESQPLVQTAVTTIPAPT-DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678

Query: 1042 KVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101
             + P  +S V+  L   T Y+++V  +      +  QG  TT      PR  + +D T +
Sbjct: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738

Query: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161
            +  ++W      + G++V   P      + +  + P   +  +  L+ GT YK+ ++ + 
Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1797

Query: 1162 DGGESSPLVGQEMTTLSDTTVMPILSS 1188
            D   SSP+V    T +   + +  L++
Sbjct: 1798 DNARSSPVVIDASTAIDAPSNLRFLAT 1824



 Score =  202 bits (515), Expect = 3e-51
 Identities = 238/984 (24%), Positives = 396/984 (40%), Gaps = 98/984 (9%)

Query: 1376 CNSVKGPGDLEAPSNLVISERTHR--SFRVSWTPPSDS-VDRYKVEYYPVSG-GKRQEFY 1431
            C  ++       P  + I+E   +  S  + W  P  S + +Y + + P +  G+ +E  
Sbjct: 599  CQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEAT 658

Query: 1432 VSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKG--TEKTLPVPVVSLNIYDVGPTT 1489
            +     S  +K LKP   Y   + S+ +  + E  +   T  +   PV S  +   G TT
Sbjct: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTV--TGETT 716

Query: 1490 MHVQWQPVGG---------ATGYILSYKPVKDT------------EPTRPKEVRLGPTVN 1528
                + P+           A+ +++S+    DT            E   P+ + L  T  
Sbjct: 717  ---PFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773

Query: 1529 DMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEP 1588
             + + DL+P  +Y V V  +  D     +     T     P D  +  V  +++ V W  
Sbjct: 774  SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSR 833

Query: 1589 VPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS--LKDLFSQTLYTVSVSAVHDEGESPPV 1646
                +  Y + Y +P  +    E++  ET+ S  L DL     Y +++ AV +  ES PV
Sbjct: 834  PQAPITGYRIVY-SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV 892

Query: 1647 TAQETTR------PVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMET 1700
              Q+ T        VP+P +L+  EVT       W    S V+ YR+   P     +   
Sbjct: 893  VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ 952

Query: 1701 ILNGDENTLV-FENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPK-SGPRN 1758
             L    NT      L+P   Y   + A+                 P+   Q  K   P N
Sbjct: 953  RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----------PLTAQQTTKLDAPTN 1002

Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
            LQ  N T +++ V+W P   ++  YR+T    T  G  +   +G   +   L+ L+P + 
Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061

Query: 1819 YTITVSSLYPDGEGGRMTGRGKT-------KPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871
            YT+++ ++  + E  + TG   T        P NT       + + +T+ + W  A   P
Sbjct: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-------EVTETTIVITWTPA---P 1111

Query: 1872 R-QYKLFYAPAAGG--PEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDT 1928
            R  +KL   P+ GG  P E+    G+    ++  L P   Y  T+  V  +G   R +  
Sbjct: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSI---VVSGLTPGVEYVYTI-QVLRDGQE-RDAPI 1166

Query: 1929 GRTLMRGLARNVQVY---NPTPNSLDVRWDPAPGP-VLQYRVVYSPVDGTRPSE-SIVVP 1983
               ++  L+    ++   NP    L V W+ +  P +  YR+  +P +G + +    VV 
Sbjct: 1167 VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226

Query: 1984 GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGETTNSLS 2042
             +      + L P   Y+V++  +  D E    P     +P    P +LR      +++ 
Sbjct: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKES--VPISDTIIPAVPPPTDLRFTNIGPDTMR 1284

Query: 2043 VAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYED 2101
            V W       +  + + YSP   +      ++    N V+L  L P T Y ++V +VYE 
Sbjct: 1285 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1344

Query: 2102 GDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVG-SNEPME 2160
             +   L G  +T GL  P  I  SD     F V W    + + GY+I + P   S  P E
Sbjct: 1345 HESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1403

Query: 2161 AFVGEM-TSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDT 2219
              V     S TL NL P T Y V++ A      S  L  Q +T+     DL+       +
Sbjct: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS 1463

Query: 2220 FCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTVFVQTP 2277
              + W +P      YR+      G    QE TV GS+++   +GL P  DY +TV+  T 
Sbjct: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523

Query: 2278 NLEGPG----VSVKEHTTV-KPTE 2296
              + P     +S+   T + KP++
Sbjct: 1524 RGDSPASSKPISINYRTEIDKPSQ 1547



 Score =  200 bits (508), Expect = 2e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679

Query: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738

Query: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798

Query: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858

Query: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912

Query: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972

Query: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031

Query: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089

Query: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142

Query: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199

Query: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257

Query: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316

Query: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376

Query: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436

Query: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304
             P + + + +TV   P +      TP
Sbjct: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461



 Score =  184 bits (468), Expect = 9e-46
 Identities = 215/925 (23%), Positives = 375/925 (40%), Gaps = 86/925 (9%)

Query: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963

Query: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051

Query: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104

Query: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164

Query: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
              A  +S    +L P   Y V+V    +D  S+P++  +T       P +L+ T+   D+
Sbjct: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282

Query: 739  FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796
             ++TW   P   +  + + Y PV   E   E++  P+     L NL+P T+Y VSV   Y
Sbjct: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342

Query: 797  FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855
                 TPL G   T     +P  +  SD T ++  + W      +  Y + + P    G 
Sbjct: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400

Query: 856  TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915
             +E  V     +  L  L  GT+Y +S+ AL        L G+ +T+ +   P+DL    
Sbjct: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458

Query: 916  ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975
             T TS+   W +    VR YR+++     +    E  +P       I  L+P   Y I+V
Sbjct: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518

Query: 976  FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
            +A    G+     +P++ +  TE+ + S+ ++V +  +N++ V W P+   V  YRV   
Sbjct: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577

Query: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089
            P +G G        P  T   ++ LQP   Y ++V      GE + L Q + TT     +
Sbjct: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTT---IPA 1634

Query: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRA 1149
            P +LK +  T +S    W P   ++ GY+V   P      + E+ + P  ++VV+  L  
Sbjct: 1635 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1694

Query: 1150 GTTYKVNVFGMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRA 1196
             T Y+V+V+ + D   S P  G               +T  ++TT+     +  E +T  
Sbjct: 1695 ATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGF 1754

Query: 1197 EADIVLLVDGSWSIGRANFRTVRSF 1221
            + D V   +G   I R     VRS+
Sbjct: 1755 QVDAV-PANGQTPIQRTIKPDVRSY 1778



 Score =  177 bits (449), Expect = 1e-43
 Identities = 148/554 (26%), Positives = 237/554 (42%), Gaps = 29/554 (5%)

Query: 635  PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693
            P+DL     T      +W      V  Y ITY E  G+  V     P S ++  +S LKP
Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510

Query: 694  ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749
               Y + V A    G     S P++    TE  K  P  ++VTD   +S  + W  +   
Sbjct: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1568

Query: 750  VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808
            V  YR+   P  G G ++  T  P+Q   T+E L P  +Y VSV  +  SG   PL   A
Sbjct: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 809  ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAG-GETQEVTVRGDTTN 867
             T      P DL+ +  T +++   W+    ++  Y V  TP    G  +E+ +  D+++
Sbjct: 1629 VTTIPA--PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSS 1686

Query: 868  TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927
             V+ GL   T+Y +SV AL  +       G  TTLE    P+     D T+T+I   W +
Sbjct: 1687 VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRT 1746

Query: 928  APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987
                + G++V            ++ +  D     I  LQP T Y+I ++    +    P+
Sbjct: 1747 KTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1805

Query: 988  TGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPT 1046
              DA+T +   S  L+    T N++ V+W+P   ++  Y + Y +P    +++V +  P 
Sbjct: 1806 VIDASTAIDAPSN-LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864

Query: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106
            VT   +  L+P T Y I V+ +      K  Q S     R       KT    +S   ++
Sbjct: 1865 VTEATITGLEPGTEYTIYVIAL------KNNQKSEPLIGR------KKTGQEALSQTTIS 1912

Query: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
            W P   +   Y ++ HP G D    +  V     +  L  L  G TY + V  + D  + 
Sbjct: 1913 WAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--QQ 1969

Query: 1167 SPLVGQEMTTLSDT 1180
               V +E+ T+ ++
Sbjct: 1970 RHKVREEVVTVGNS 1983



 Score =  161 bits (407), Expect = 1e-38
 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)

Query: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944

Query: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002

Query: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062

Query: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119

Query: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176

Query: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232

Query: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020
              +NL P  +Y +SV+      E  P++ D           L+      +TMRVTW P P
Sbjct: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291

Query: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077
               + N+ V Y P  + ++ VA+  + P+  + VL  L P T Y ++V  +Y+  E    
Sbjct: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350

Query: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137
            +G   T     SP  +  SD T +SF V W      + GY++  HP     R  E  V  
Sbjct: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408

Query: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179
              N++ L  L  GT Y V++  + +G E SPL+  + +T+SD
Sbjct: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449



 Score =  155 bits (391), Expect = 8e-37
 Identities = 152/660 (23%), Positives = 255/660 (38%), Gaps = 58/660 (8%)

Query: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695

Query: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755

Query: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815

Query: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875

Query: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935

Query: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993

Query: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052

Query: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107

Query: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD--------- 2189
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D         
Sbjct: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167

Query: 2190 SGLSVPLTDQGTTLYLNVT-DLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQ-- 2246
            + +  PL+   T L+L    D     + W+      S     T YR+  +P +G +G   
Sbjct: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWER-----STTPDITGYRITTTPTNGQQGNSL 1221

Query: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306
            E  V   ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270



 Score =  147 bits (370), Expect = 2e-34
 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)

Query: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857

Query: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917

Query: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977

Query: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035

Query: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094

Query: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148

Query: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266

Query: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
               P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P DN VVL 
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
             L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362



 Score =  140 bits (352), Expect = 3e-32
 Identities = 176/796 (22%), Positives = 303/796 (38%), Gaps = 82/796 (10%)

Query: 334  VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392
            V PP++L    +    +++ W P PS  +T + V  +P+        LS+ P    + + 
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 393  DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450
            +L   TEY +SVS++     S P+   +KT           G+D    I F  +   S++
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375

Query: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHTE--FTLKKFTKVEDIIEAI 507
            +   +++  RA     +  + I  +    S   +  R PH+    TL   T   + + +I
Sbjct: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428

Query: 508  NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565
                 R  S             + +  + + S+VP+ + ++    +S   ++  PA+ +R
Sbjct: 1429 VALNGREESP------------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476

Query: 566  -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614
                       NS V+ F V      +S        P   +  TV      +  S   ++
Sbjct: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532

Query: 615  SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672
             I +    E+          P  +  ++V        W P+   V  Y +T   K   G 
Sbjct: 1533 PISINYRTEIDK--------PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584

Query: 673  DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732
             +     P   T + +  L+P   Y+V+V A+   G S PL   +T      AP +LK T
Sbjct: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV--QTAVTTIPAPTDLKFT 1641

Query: 733  DETTDSFKITWTQAPGRVLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVS 791
              T  S    WT    ++  YR+   P    G  +E+   P+     +  L+  TKYEVS
Sbjct: 1642 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1701

Query: 792  VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV 851
            V     +    P  G   T E    PR  RV+D T +T+ +SW      +  + V   P 
Sbjct: 1702 VYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA 1761

Query: 852  AGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDL 911
             G    + T++ D  +  + GL+ GT Y + +  L  +     +  + +T  +  +P +L
Sbjct: 1762 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID--APSNL 1819

Query: 912  VTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKY 971
                 T  S+   W      + GY + ++                     I  L+P T+Y
Sbjct: 1820 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1879

Query: 972  RISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031
             I V A  ++ + EPL G             K  +E  +   ++W P       Y +   
Sbjct: 1880 TIYVIALKNNQKSEPLIG-----------RKKTGQEALSQTTISWAPFQ-DTSEYIISCH 1927

Query: 1032 PHGRGKQ-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSP 1090
            P G  ++ +  +VP T TS  L  L    TY+I V  +      K+R+   T  +     
Sbjct: 1928 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 1987

Query: 1091 RNLKTSDPTMSSFRVT 1106
             N  T D     + V+
Sbjct: 1988 LNQPTDDSCFDPYTVS 2003



 Score = 66.6 bits (161), Expect = 4e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859

Query: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916

Query: 134 SVS 136
            V+
Sbjct: 917 EVT 919



 Score = 65.5 bits (158), Expect = 8e-10
 Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 7/118 (5%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600

Query: 83   ELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSA-WT 139
             L P  EYVV++ + +   ES P+     +QT  +T P       T++   S+SA WT
Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPL-----VQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653



 Score = 58.9 bits (141), Expect = 7e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108



 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82
            V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    +L+
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326

Query: 83   ELVPETEYVVTITSYDEVEESVPVIGQ 109
             L+P TEYVV+++S  E  ES P+ G+
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 1624 LVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1683

Query: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 1684 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1719



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849

Query: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223

Query: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 25/96 (26%), Positives = 44/96 (45%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            ++     ++ PSNL  +  +   + ++W P  + +TGY +      +  R+      P  
Sbjct: 1806 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1865

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
            T  ++  L   TEY I V A+K    SEP+   +KT
Sbjct: 1866 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1901



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498

Query: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542

Query: 131  QKCSVSAWTDL 141
             K S    TD+
Sbjct: 1543 DKPSQMQVTDV 1553



 Score = 42.7 bits (99), Expect = 0.005
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 1813 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1872

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109
            L P TEY + + +    ++S P+IG+
Sbjct: 1873 LEPGTEYTIYVIALKNNQKSEPLIGR 1898



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 1705 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1763

Query: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 1764 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1806



 Score = 36.2 bits (82), Expect = 0.51
 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)

Query: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
            +V+  E V PP      + +   + ++W      +TG++V   P   G      ++ P  
Sbjct: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1775

Query: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446
             + ++  L   T+Y+I +  +     S P           V ++ S  +D  +++ FL  
Sbjct: 1776 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1824

Query: 447  GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494
               S+ + ++   RA +   +  +E  P      +V   R   TE T+
Sbjct: 1825 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1870



 Score = 35.0 bits (79), Expect = 1.1
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966

Query: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797

Query: 102 ESVPVIGQLTIQTGSSTKP 120
           E       L + T  +T P
Sbjct: 798 EQ-----SLILSTSQTTAP 811



 Score = 32.7 bits (73), Expect = 5.7
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)

Query: 312  IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
            ++S V     E+   L+  +  V + P +L  +  +   + ++W+     V  Y++    
Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484

Query: 371  MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423
                S     +V    +T ++  L    +Y I+V A+ G      SS+PISI  +T+   
Sbjct: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544

Query: 424  PMKVQV 429
            P ++QV
Sbjct: 1545 PSQMQV 1550


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
            sapiens]
          Length = 921

 Score =  333 bits (854), Expect = 2e-90
 Identities = 202/575 (35%), Positives = 274/575 (47%), Gaps = 81/575 (14%)

Query: 2508 CPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTAD 2567
            CP I +     PGF ++  + + +   AS + +    GS     AY++  N     PT +
Sbjct: 44   CPKIRIGQDDLPGFDLISQFQVDKA--ASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRN 101

Query: 2568 LHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTR 2627
            L+P+GLP  Y+ +  FR+   T    + IWQI D   K QVG+  +  ++++ F  K   
Sbjct: 102  LYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLD 161

Query: 2628 GEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEI 2687
            G +QT  F    + +LF   +HK+ I V   S  +++DC  I    IK  G I  DG+ +
Sbjct: 162  GSLQTAAFSN--LSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAV 219

Query: 2688 LGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVG 2747
            LGKL    + S  F++Q   I C P+   R+ C ++P+R      P+            G
Sbjct: 220  LGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARIT----PSQTTDERGPPGEQG 275

Query: 2748 PPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP-GEQG 2806
            PPGPPGP G PG  G  G+RG  G  GPPGP G+ G PG  G PG  G +GL+ P G  G
Sbjct: 276  PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPG 335

Query: 2807 RQGMKGDAGEPGLPGRTGTPGL--------------------------------PGPPGP 2834
              G KG  GEPG+PG  G PG                                 PGPPGP
Sbjct: 336  SIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGP 395

Query: 2835 MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGD 2894
             GP G  GF   D       PPG  G PG PG+ G  G  G+ G+ GR G  G +G++G+
Sbjct: 396  PGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE 455

Query: 2895 RGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAG 2954
             G++ +Q                             P   Q  R   G  G  G  G+ G
Sbjct: 456  LGEVGAQG----------------------------PPGAQGLRGITGIVGDKGEKGARG 487

Query: 2955 ARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGES----- 3009
              GEPGP G PG PG  G +GPPGE G  G++     G+ G RG+PG PGP+G++     
Sbjct: 488  LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR-----GAEGARGIPGLPGPKGDTGLPGV 542

Query: 3010 --RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              R G PG  G++G PG PG PG++G++G PG PG
Sbjct: 543  DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577



 Score =  253 bits (647), Expect = 2e-66
 Identities = 148/353 (41%), Positives = 177/353 (50%), Gaps = 45/353 (12%)

Query: 2742 TQDSVGPPGPPGPAGG---------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            T+   G PGPPG AG          PGAKG  GE+G +GA G PG  G+ G PG QGPPG
Sbjct: 554  TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 613

Query: 2793 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--------------- 2836
              GP G   +PG +G  G  G  G PG  G  G+PGLPG PGP G               
Sbjct: 614  EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 673

Query: 2837 PPGDRGFTGKDGAMGPRGP------PGPPGS---PGSPGVTGPSGKPGKPGDHGRPGPSG 2887
            P G++G +G++G  G RG       PGP GS   PG PG+ GP G  G PG  G  GP G
Sbjct: 674  PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 733

Query: 2888 LKGEKGDRGDIASQNMMRAVAR--------QVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939
             +G +G++G      +     R        QVC ++I          L +  +       
Sbjct: 734  PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 793

Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGL 2999
            +PGPPGPPGPPG  G  G+ G  G PG  G PG  G  G +G  GEKGERG    GP GL
Sbjct: 794  RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGL 853

Query: 3000 PGP---PGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQC 3049
            PG    PG  G +  G  G  G RGPPG  G PG  G  GPPG PG+C+ + C
Sbjct: 854  PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906



 Score =  232 bits (591), Expect = 5e-60
 Identities = 149/358 (41%), Positives = 174/358 (48%), Gaps = 41/358 (11%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P  PN+C   +   G PG PG  G  GAKG  GE G  G  G  G +G++G  G QGPPG
Sbjct: 409  PLCPNACPPGRS--GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 466

Query: 2793 PQGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK-- 2846
             QG  G++      GE+G +G+ G+ G  GLPG  G  G  GPPG  GP GDRG  G   
Sbjct: 467  AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 526

Query: 2847 -DGAMGPRGPPGPPGS------PGSPGVTGPSGKPGKPGDHGR---------PGPSGLKG 2890
              G  GP+G  G PG       PG PG  G  GKPG PGD G          PG  G+ G
Sbjct: 527  IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG 586

Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950
            EKG  G       M    +        GQ     ++  + P     SR + GP G PG P
Sbjct: 587  EKGSTGAPGKPGQMGNSGKP-------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 639

Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPRGLPGP---P 3003
            G  G+ G PG  G PG PG PGM+G  G  G PG KGE+G     G +G RG  G    P
Sbjct: 640  GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 699

Query: 3004 GPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            GP+G +  G PG  G RGP G  G PG  G RGPPGP G         +P   QG PG
Sbjct: 700  GPKGSA--GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP-GVQGPPG 754



 Score =  212 bits (539), Expect = 5e-54
 Identities = 148/393 (37%), Positives = 168/393 (42%), Gaps = 101/393 (25%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---PRGDIG------------------PP 2785
            G PG  G  G PG  GP+G+RG  GA G PG   P+GD G                   P
Sbjct: 499  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558

Query: 2786 GPQGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844
            G  GPPG  G  GL  +PG  G +G+ G+ G  G PG+ G  G  G PG  GPPG+ G  
Sbjct: 559  GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 618

Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 2904
            G  G  G RG  GP GSPG PG  G  G PG PG    PGP GL G KGDRG +      
Sbjct: 619  GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPK 675

Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG---P 2961
                    EQ  SG+     +            R + G  G PGP GSAG  GEPG   P
Sbjct: 676  G-------EQGASGEEGEAGE------------RGELGDIGLPGPKGSAGNPGEPGLRGP 716

Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG------------------------------- 2990
             G  G PG  G +GPPG RG+ GE+G  G                               
Sbjct: 717  EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 776

Query: 2991 ------------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGP- 3037
                        TG  G  G PGPPGP GE+  G PG  G RG PG  G PG  G+RGP 
Sbjct: 777  MAASLKRPDSGATGLPGRPGPPGPPGPPGEN--GFPGQMGIRGLPGIKGPPGALGLRGPK 834

Query: 3038 --------PGPPGYCDSSQCASIPYNGQGYPGS 3062
                     GPPG   +    +I   G   P S
Sbjct: 835  GDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 867



 Score =  107 bits (268), Expect = 1e-22
 Identities = 79/245 (32%), Positives = 90/245 (36%), Gaps = 95/245 (38%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL------ 2799
            VG PGP G  G  G +G  GERG  G IG PGP+G  G PG  G  GP+G  GL      
Sbjct: 669  VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 728

Query: 2800 -------SIPGEQGRQGMKGDAGEPGLP------------------------------GR 2822
                    + GEQG  G+ G  G PG                                G 
Sbjct: 729  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788

Query: 2823 TGTPGLPGPPGPMGPPGDRGFTGK------------DGAMGPRGPPG---------PPGS 2861
            TG PG PGPPGP GPPG+ GF G+             GA+G RGP G         PPG 
Sbjct: 789  TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 848

Query: 2862 -------------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890
                                           PG  G+ G  G PG PG  G   P+    
Sbjct: 849  GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 908

Query: 2891 EKGDR 2895
            + G R
Sbjct: 909  QAGQR 913



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 51/121 (42%), Positives = 60/121 (49%), Gaps = 25/121 (20%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG------PRGDIGPPGPQGPPGPQGPNGL- 2799
            GPPGPPGP G  G  G  G RG+ G  GPPG      P+GD+G  G +GPPG +GPNGL 
Sbjct: 796  GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 854

Query: 2800 ---SIPGEQG-----RQGMKGDAGEPGL---------PGRTGTPGLPGPPGPMGPPGDRG 2842
                +PG+ G     R G  G+ G PG+         PG  G PG   P       G R 
Sbjct: 855  GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 914

Query: 2843 F 2843
            F
Sbjct: 915  F 915


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score =  278 bits (710), Expect = 8e-74
 Identities = 194/651 (29%), Positives = 277/651 (42%), Gaps = 136/651 (20%)

Query: 2500 VCETATSSCPLIYLDGY--TSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQK 2557
            V +    SCP++ ++G+  T      LE       +  S++    ES      + +++  
Sbjct: 26   VRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLGDSFSLRRAFCESDK----TCFKLG- 80

Query: 2558 NAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSK 2617
            +A + + T  + P GLP  Y++  +FR+      + + +WQ+ ++   PQ+ ++ D   K
Sbjct: 81   SALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNIPQISIVVDGGKK 140

Query: 2618 TLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEA 2677
             + F  + T G+V    F   E++ LF   +HK+ I + S+ + +Y+DC  I  +   E 
Sbjct: 141  VVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMDCNLIARRQTDEK 200

Query: 2678 GNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCP---- 2733
              +   G  ++      + K    ++    I CS    +++ CC+I     + KCP    
Sbjct: 201  DTVDFHGRTVIA-TRASDGKPVDIELHQLKIYCSANLIAQETCCEI----SDTKCPEQDG 255

Query: 2734 ------------------------AFPNSCTC--TQDSVGPPGPPGPAGGPGAKGPRGER 2767
                                       + C C   +   G PG PG  G  G KG  GE 
Sbjct: 256  FGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGEN 315

Query: 2768 GISGAIGPPGPRGDIGPPGPQGPPGPQGPNG----LSIPGEQGRQGMKGDA---GEPGLP 2820
            G+ GA G PG +G+ G  G +G  G +G  G     ++ G  G  G+KGD    G PG  
Sbjct: 316  GLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPK 375

Query: 2821 GRTGTPGLPGPP---------GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGV---- 2867
            G  G  G PGPP         GP GPPG  G  G+ G  GP G PGPPG PG PG+    
Sbjct: 376  GEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIH 435

Query: 2868 ----------------------TGPSGKPGKPGDHGRPGPSGLKGE------KGDRGDIA 2899
                                   G  G+ G PG  G  GP G KGE      KG++GD  
Sbjct: 436  QTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRG 495

Query: 2900 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 2959
               ++ +                            Q  + +PG PGPPG  GS G +G+ 
Sbjct: 496  EPGVIGS----------------------------QGVKGEPGDPGPPGLIGSPGLKGQQ 527

Query: 2960 ------GPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGP---PGPQGESR 3010
                  GP G PG  G PG  G PG++G+ GEKG+ G G  GP GLPGP    GP G+S 
Sbjct: 528  GSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-GIIGPPGLPGPKGEAGPPGKSL 586

Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             G PG  G+ G PGP G  G  G+ G  G PG         I   G G PG
Sbjct: 587  PGEPGLDGNPGAPGPRGPKGERGLPGVHGSPG--------DIGPQGIGIPG 629



 Score =  214 bits (544), Expect = 1e-54
 Identities = 143/358 (39%), Positives = 161/358 (44%), Gaps = 106/358 (29%)

Query: 2746 VGPPGPPGPAGGPGAKGPRG------ERGISGAIGPPGP------RGDIGPPGPQGPPGP 2793
            +GP GPPGP G  G  GP G        GI G  GPPG       RG  GPPG  GPPGP
Sbjct: 366  LGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGP 425

Query: 2794 QGPNGL-----SIPG----------EQGRQGMKGDAGEPGLPGRTGT------PGLPGPP 2832
             GP G+     ++ G          E    G+KGD GE GLPG  G+       G PG P
Sbjct: 426  PGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEP 485

Query: 2833 GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG---SPGVTG------------PSGKPGKP 2877
               G  GDRG  G  G+ G +G PG PG PG   SPG+ G            P G  G P
Sbjct: 486  FTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLP 545

Query: 2878 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSS 2937
            G+HG PG  G+KGEKGD G I                                       
Sbjct: 546  GEHGIPGKQGIKGEKGDPGGII-------------------------------------- 567

Query: 2938 RNQPGPPGPPGPPGSAGARGE--PGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----- 2990
                GPPG PGP G AG  G+  PG  G  G PG PG +GP GERGLPG  G  G     
Sbjct: 568  ----GPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQ 623

Query: 2991 -------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041
                   TG+ GP G PG  GP+G    G PG+ G+ G  G PGR G  G+ GPPG P
Sbjct: 624  GIGIPGRTGAQGPAGEPGIQGPRG--LPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDP 679



 Score =  212 bits (539), Expect = 5e-54
 Identities = 142/385 (36%), Positives = 163/385 (42%), Gaps = 101/385 (26%)

Query: 2746 VGPPGPPGPAG--GPGAKGPRGERGISG---AIGPPGPRGDIGPPGPQGPPGPQGPNGLS 2800
            +GPPG PGP G  GP  K   GE G+ G   A GP GP+G+ G PG  G PG  GP G+ 
Sbjct: 567  IGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIG 626

Query: 2801 IPGEQGRQGMKGDAG------------EPGLPGRTGTPGLPGPPGPMGPPGD-------- 2840
            IPG  G QG  G+ G             PG PG  G PG  G PG  GPPGD        
Sbjct: 627  IPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLG 686

Query: 2841 ------RGFTG-----------------------------KDGAMGPRGPPGPPGS---- 2861
                  + F G                             + G +GPRGPPG PG     
Sbjct: 687  DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPK 746

Query: 2862 -----------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDI 2898
                                   PG PG  GP+G PG  G  G PGP+G KGEKG  G  
Sbjct: 747  GSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPP 806

Query: 2899 ASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE 2958
                          E+     + +    +N +P       + PGPPGPPGP G  G  GE
Sbjct: 807  GKPGPPGPPGIPFNERNGMSSLYKIKGGVN-VP-------SYPGPPGPPGPKGDPGPVGE 858

Query: 2959 PGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGST 3017
            PG  G PG  G PG++G  G  G PG       G SG  G PGPPG  GE    GP G  
Sbjct: 859  PGAMGLPGLEGFPGVKGDRGPAGPPGI-----AGMSGKPGAPGPPGVPGEPGERGPVGDI 913

Query: 3018 GSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G  GP GP G+PG +G  G PG  G
Sbjct: 914  GFPGPEGPSGKPGINGKDGIPGAQG 938



 Score =  211 bits (537), Expect = 9e-54
 Identities = 140/367 (38%), Positives = 158/367 (43%), Gaps = 104/367 (28%)

Query: 2747 GPPGPPGPAGGPGA----------------------KGPRGERGISGAIGPPGP------ 2778
            G PG PGP G P A                       G +  +G  G  G PG       
Sbjct: 668  GKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMAR 727

Query: 2779 RGDIGPPGPQGPPGPQGPNGLS-------IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 2831
            +GDIGP GP G PG +GP G         IPGE+G +G++G  G PG PG TG PGL G 
Sbjct: 728  KGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGR 787

Query: 2832 PGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP-----------------------GSPGVT 2868
             G  GP G +G  G DG  G  GPPGPPG P                       G PG  
Sbjct: 788  TGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPP 847

Query: 2869 GPSGKPG---KPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925
            GP G PG   +PG  G PG  G  G KGDRG                             
Sbjct: 848  GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG-------------------------- 881

Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGPGGRPGFPGTPGMQGPPGE 2979
                 P        +PG PGPPG PG  G RG       PGP G  G PG  G  G PG 
Sbjct: 882  -----PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA 936

Query: 2980 RGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPP 3038
            +G+ G+ G+RG  G  G +G+PG  G QGE   G PG TG +G  GP G PGN G  G P
Sbjct: 937  QGIMGKPGDRGPKGERGDQGIPGDRGSQGER--GKPGLTGMKGAIGPMGPPGNKGSMGSP 994

Query: 3039 ---GPPG 3042
               GPPG
Sbjct: 995  GHQGPPG 1001



 Score =  208 bits (530), Expect = 6e-53
 Identities = 147/410 (35%), Positives = 166/410 (40%), Gaps = 118/410 (28%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SI 2801
            +GP GPPG  G  G KG +GERG  G  G  G  G  G PG  G PGP GP GL      
Sbjct: 731  IGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGH 790

Query: 2802 PGEQGRQGMKGDAGEPGLPGRTGTPGL-----------------------PGPPGPMGPP 2838
            PG  G +G KG  G PG PG  G PG+                       PGPPGP GP 
Sbjct: 791  PGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPK 850

Query: 2839 GDRGFTGKDGAM---------------GPRGPPGPPGSPGSPGVTGPSGKPGKP------ 2877
            GD G  G+ GAM               GP GPPG  G  G PG  GP G PG+P      
Sbjct: 851  GDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPV 910

Query: 2878 GDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQ-IPND--Y 2934
            GD G PGP G  G+ G  G          + +        G      +  +Q IP D   
Sbjct: 911  GDIGFPGPEGPSGKPGINGKDGIPGAQGIMGK-------PGDRGPKGERGDQGIPGDRGS 963

Query: 2935 QSSRNQP---------GPPGPPGPPGSAGARGEPGPGGRPGFPGTP-------------- 2971
            Q  R +P         GP GPPG  GS G+ G  GP G PG PG P              
Sbjct: 964  QGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYIN 1023

Query: 2972 ------------------------------GMQGPPGERGLPGEKGERGTGSSGPRGLPG 3001
                                          G  GPPG+ GLPG  G+      GP+G  G
Sbjct: 1024 QEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD-----PGPQGYRG 1078

Query: 3002 PPGPQGESRTGPPGSTGSRGPP--GPPGRPGNSGIRGPPGPPGYCDSSQC 3049
              G +GE   G PGS G  G    G PG PG  G +GPPGP G C+   C
Sbjct: 1079 QKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128



 Score =  145 bits (367), Expect = 5e-34
 Identities = 100/296 (33%), Positives = 115/296 (38%), Gaps = 100/296 (33%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP---PGPRGDIGPPGPQ- 2788
            PA P          G PGPPG  G PG +GP G+ G  G  GP   PG  G  G PG Q 
Sbjct: 879  PAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQG 938

Query: 2789 --GPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK 2846
              G PG +GP      GE+G QG+ GD G  G  G+ G  G+ G  GPMGPPG++G  G 
Sbjct: 939  IMGKPGDRGPK-----GERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS 993

Query: 2847 DGAMGPRGPPGPPGSPGSP----------------------------------------- 2865
             G  GP G PG PG P                                            
Sbjct: 994  PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053

Query: 2866 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQ 2925
            G  GP GK G PG  G PGP G +G+KG+RG+                            
Sbjct: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI------------------------- 1088

Query: 2926 MLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERG 2981
                            G PG PG PG++         G PG PG PG QGPPG  G
Sbjct: 1089 ----------------GLPGSPGLPGTSAL-------GLPGSPGAPGPQGPPGPSG 1121



 Score = 85.5 bits (210), Expect = 7e-16
 Identities = 56/153 (36%), Positives = 63/153 (41%), Gaps = 49/153 (32%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISG---------------------------------- 2771
            +GPPG  G  G PG +GP G  GI G                                  
Sbjct: 982  MGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041

Query: 2772 ----------AIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPG 2821
                      A G PGP G  G PGP G PGPQG  G    GE+G  G+ G  G PGLPG
Sbjct: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK--GERGEPGI-GLPGSPGLPG 1098

Query: 2822 RT--GTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
             +  G PG PG PGP GPPG  G    +  + P
Sbjct: 1099 TSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131



 Score = 56.2 bits (134), Expect = 5e-07
 Identities = 32/77 (41%), Positives = 35/77 (45%), Gaps = 10/77 (12%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGI----------SGAIGPPGPRGDIGPPGPQGPPGPQGP 2796
            GPPG PGP G  G KG RGE GI          + A+G PG  G  GP GP GP G   P
Sbjct: 1066 GPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125

Query: 2797 NGLSIPGEQGRQGMKGD 2813
                 P     Q   G+
Sbjct: 1126 EDCLYPVSHAHQRTGGN 1142


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  264 bits (675), Expect = 9e-70
 Identities = 154/345 (44%), Positives = 181/345 (52%), Gaps = 47/345 (13%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERG---ISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IP 2802
            GPPG  G  G  GA GPRGE G   + G  G PG  GD GP GPQGP GP+GP G +  P
Sbjct: 720  GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779

Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPG---PPGPMGPPGDRGFTGKDGA---------- 2849
            G  G  G  G  G+ G  G  G+PGLPG   P GP G PG++G  GK+G           
Sbjct: 780  GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 839

Query: 2850 --------MGPRGPPGPPGSPGSPGVTG---------PSGKPGKPGDHGRPGPSGLKGEK 2892
                     G +GPPG  G PG PG+ G         P G PG+ G  G PGP G  G  
Sbjct: 840  GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 899

Query: 2893 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-QSSRNQPGPPGPPGP-- 2949
            G RG+  S   +R   R + E+L      R   +L Q+P  Y +SS+ +PGPPGPPG   
Sbjct: 900  GLRGESPSMETLR---RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 956

Query: 2950 -PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTG---SSGPRGLPGPPGP 3005
             PG AG  GEPG  G+ G  G  G  GP GERG  G+ G  G G     GP G+PG PG 
Sbjct: 957  LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGE 1016

Query: 3006 QGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 3050
             G ++ G PG  G +G  GP G PG   + GPPGPPG CD SQCA
Sbjct: 1017 PGYAKDGLPGIPGPQGETGPAGHPG---LPGPPGPPGQCDPSQCA 1058



 Score =  247 bits (630), Expect = 1e-64
 Identities = 142/314 (45%), Positives = 164/314 (52%), Gaps = 67/314 (21%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SIPGEQ 2805
            G PG PG  G PG  GP G  GI+GA GPPG +G    PG +GPPGPQGP+GL  IPGE+
Sbjct: 633  GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS---PGKEGPPGPQGPSGLPGIPGEE 689

Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------PGPP 2859
            G++G  G  G PG PG+ G PGLPGP G  GPPG +G TG  GA GPRG       PG  
Sbjct: 690  GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 749

Query: 2860 GSPGSPGVTGPS------------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
            G PG  G TGP+            GK G PG  G PGPSG  G+KG +G+  S  +    
Sbjct: 750  GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---- 805

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967
                                             PG  GP GPPG  G +G PG  G PG 
Sbjct: 806  ---------------------------------PGFLGPRGPPGEPGEKGVPGKEGVPGK 832

Query: 2968 PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGP 3022
            PG PG +   GERG PG KG++G  G  G  G PG PG +G +      G PG  G  GP
Sbjct: 833  PGEPGFK---GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 889

Query: 3023 PGPPGRPGNSGIRG 3036
            PGPPG+PG  G+RG
Sbjct: 890  PGPPGQPGFPGLRG 903



 Score =  241 bits (616), Expect = 6e-63
 Identities = 147/333 (44%), Positives = 164/333 (49%), Gaps = 42/333 (12%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL-SI 2801
            Q   G  GP GP G PGAKG  G  G  GA G PG  G +G PGP GPPG  G  GL   
Sbjct: 367  QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGT 426

Query: 2802 PGEQGRQGMKGDAGEPGLPGRT------GTPGLPGPP--GPMGPPGDRGFTGKDGAMGPR 2853
            PG+ G +G KG AGE G PG        G PGLPGPP  G  G PG RG  G  G +G +
Sbjct: 427  PGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK 486

Query: 2854 GPPGPPGSPGSP--------GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--------D 2897
            G  G PG PGSP        GV GP G  G PGD G PG  GL G  G +G         
Sbjct: 487  GDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSS 546

Query: 2898 IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARG 2957
            + S   +  +A+ VC     G        L  +P      +   G PG PG  G+ G +G
Sbjct: 547  LLSPGDINLLAKDVCNDCPPGPPG-----LPGLP----GFKGDKGVPGKPGREGTEGKKG 597

Query: 2958 EPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGPPGPQG-ES 3009
            E GP G PG PG  G QG  GERG  GE G++G        G  GP G PGPPG  G   
Sbjct: 598  EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 657

Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              GPPG  GS G  GPPG  G SG+ G PG  G
Sbjct: 658  AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 690



 Score =  228 bits (580), Expect = 9e-59
 Identities = 142/356 (39%), Positives = 161/356 (45%), Gaps = 52/356 (14%)

Query: 2724 PSRRDEGKCPAFPN--SCTCTQDSVGPPGPPGPAGGPGA------KGPRGERGISGAIGP 2775
            P  R E   P  P        Q   G PG  G AG PGA      +G +G++G  G +G 
Sbjct: 252  PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 311

Query: 2776 PGPRGDIGPPGPQGPPGPQGPNGLS--------IPGEQGRQGMKGDAGEPGLPGRTGTPG 2827
            PG +GD G  G  GP GP G  G +        +PGEQG +G KGD G PG PG  G PG
Sbjct: 312  PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPG 371

Query: 2828 LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG 2887
              GP GP GPPG +G  G  GA G  G PG PG  G+PG +GP G  G PG  G PG  G
Sbjct: 372  ELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 431

Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 2947
             +GEKG  G+  S   +                                 R  PG PG P
Sbjct: 432  ERGEKGAAGEEGSPGPV-------------------------------GPRGDPGAPGLP 460

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007
            GPPG  G  GEPG  G PG PG  G +G  G  G+PG  G RG    G  G PGP GP G
Sbjct: 461  GPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 519

Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRG--PPGPPGYCDSSQCASIPYNGQGYPG 3061
            +   G PGS G  G PGP G  G  G+     PG         C   P    G PG
Sbjct: 520  DK--GSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG 573



 Score =  228 bits (580), Expect = 9e-59
 Identities = 162/401 (40%), Positives = 184/401 (45%), Gaps = 89/401 (22%)

Query: 2747 GPPGPPGPAGGPGAKGP------RGERGISG---AIGPPGPRGDIGPPGPQGPP--GPQG 2795
            GP GPPG  G PG +G       RGE+G +G   + GP GPRGD G PG  GPP  G  G
Sbjct: 410  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 469

Query: 2796 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLP-----GPPGPMGPPGD------RGF 2843
              GL   PG  G  G KGD G PG+PG  G+ G P     GPPGP GPPGD      RG 
Sbjct: 470  EPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 529

Query: 2844 TGKDGAMGPRG------------------------PPGPPGSPGSPGVTGPSGKPGKPGD 2879
             G  G  GP G                        PPGPPG PG PG  G  G PGKPG 
Sbjct: 530  PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 589

Query: 2880 HGR------------PGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQM----NRF 2923
             G             PGP G+ G +G +G+  +   +     Q     + G M    N  
Sbjct: 590  EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ-GHPGVPGFMGPPGNPG 648

Query: 2924 NQMLNQI-----PNDYQSSRNQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPG 2969
                + I     P   Q S  + GPPGP GP G  G  GE         PGP G PG  G
Sbjct: 649  PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG 708

Query: 2970 TPGMQGPPGERGLPGEKGERG-TGSSGPR------GLPGPPG-PQGESRTGPPGSTGSRG 3021
             PG+ GP G RG PG KG  G +G+ GPR      GLPG  G P  +  TGP G  G +G
Sbjct: 709  EPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 768

Query: 3022 PPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ-GYPG 3061
            P GPPG+ G+ G  G PGP G     Q  S   NG  G PG
Sbjct: 769  PRGPPGKNGSPGSPGEPGPSG--TPGQKGSKGENGSPGLPG 807



 Score =  224 bits (572), Expect = 8e-58
 Identities = 152/389 (39%), Positives = 185/389 (47%), Gaps = 76/389 (19%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS------ 2800
            G  G PG  G PG +G +G++G  G +G PG +GD G  G  GP GP G  G +      
Sbjct: 283  GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH 342

Query: 2801 --IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA--------- 2849
              +PGEQG +G KGD G PG PG  G PG  GP GP GPPG +G  G  GA         
Sbjct: 343  PRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA 402

Query: 2850 ---MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRA 2906
               +G  GP GPPGS G+PG+ G  GK G+ G+ G  G  G  G  G RGD  +  +   
Sbjct: 403  PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGP 462

Query: 2907 VAR-QVCEQLISGQM-------NRFNQMLNQIPNDYQSSRNQP-----GPPGPPGPP--- 2950
              + +  E  + G          + ++    IP     SR  P     GPPGP GPP   
Sbjct: 463  PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGS-PGSRGDPGIGVAGPPGPSGPPGDK 521

Query: 2951 GSAGARGEP------GPGGR------------------------PGFPGTPGMQGPPGER 2980
            GS G+RG P      GP GR                        PG PG PG+ G  G++
Sbjct: 522  GSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581

Query: 2981 GLPGEKGERGT----GSSGPRGLPGPP---GPQG-ESRTGPPGSTGSRGPPGPPGRPGNS 3032
            G+PG+ G  GT    G +GP GLPGPP   GPQG +   G  G  G +G  G PG PG  
Sbjct: 582  GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641

Query: 3033 GIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            G  G PGPPG  D    A+ P   QG PG
Sbjct: 642  GPPGNPGPPG-ADGIAGAAGPPGIQGSPG 669



 Score =  176 bits (447), Expect = 2e-43
 Identities = 126/332 (37%), Positives = 148/332 (44%), Gaps = 53/332 (15%)

Query: 2759 GAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPG 2818
            G +GP  +R  + A      +   G     G PG +G +GL      G+ G++G+ GE G
Sbjct: 220  GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLP-----GKPGLRGEIGEQG 274

Query: 2819 LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG 2878
            L GR G  G  G PG  G PG RG  G  G  G  G PG  G  G  G  GP+G PG PG
Sbjct: 275  LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 334

Query: 2879 ------DHGR-PGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931
                   H R PG  G KGEKGD G                E  + G+           P
Sbjct: 335  TTSLFTPHPRMPGEQGPKGEKGDPG-------------LPGEPGLQGRPGELGPQGPTGP 381

Query: 2932 NDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG- 2990
               +      G PG  G PG+ G  G PGP G PG  G PG++G PG+ G  GEKG  G 
Sbjct: 382  PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 441

Query: 2991 ---TGSSGPR---GLPGPPGPQGESRTGPPGSTGSRGPPGP---------PGRPGNSGIR 3035
                G  GPR   G PG PGP G+ + G PG  GS G PGP         PG PG+ G R
Sbjct: 442  EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSR 501

Query: 3036 GPP-----GPPGYCDSSQCASIPYNGQGYPGS 3062
            G P     GPPG        S P   +G PGS
Sbjct: 502  GDPGIGVAGPPG-------PSGPPGDKGSPGS 526



 Score =  108 bits (269), Expect = 1e-22
 Identities = 59/128 (46%), Positives = 67/128 (52%), Gaps = 13/128 (10%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            PA+  S   +Q   GPPGPPG  G PG  GP GE G  G  G  GP G IGP G +G  G
Sbjct: 936  PAYMKS---SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 992

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
              G  G+ + GE G  G+ G  GEPG   + G PG+PGP G  GP G  G          
Sbjct: 993  DPGAPGVGLRGEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGPAGHPGLP-------- 1043

Query: 2853 RGPPGPPG 2860
             GPPGPPG
Sbjct: 1044 -GPPGPPG 1050



 Score =  101 bits (252), Expect = 1e-20
 Identities = 89/275 (32%), Positives = 105/275 (38%), Gaps = 79/275 (28%)

Query: 2813 DAGEPGLPGRTGTPGLPGPPGPMG--PPGDRGFTGKD--GAMGPRGPPGPPG-------- 2860
            D G  G  GR  T  LP    P    P G    TG +   A+G +GP             
Sbjct: 182  DQGAQGACGRGNTSVLPSSVAPQCSMPKG----TGHEFSAALGTQGPADQRADARASCIL 237

Query: 2861 -SPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQ 2919
             +  +PG+   +G+PG+ G+ G PG  GL      RG+I                     
Sbjct: 238  AAKTAPGLKQLNGEPGERGEDGLPGKPGL------RGEI--------------------- 270

Query: 2920 MNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE 2979
                                  G  G  G PG  G  G PG  G PG  G  G QG  GE
Sbjct: 271  ----------------------GEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE 308

Query: 2980 RGLPGEKGERGT-GSSGPRGLPGPPG--------PQGESRTGPPGSTGSRGPPGPPG--- 3027
             GLPG KG+RG  G +GP G PG PG        P+     GP G  G  G PG PG   
Sbjct: 309  LGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 368

Query: 3028 RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
            RPG  G +GP GPPG          P    G PG+
Sbjct: 369  RPGELGPQGPTGPPGAKGQEGAHGAP-GAAGNPGA 402


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  259 bits (663), Expect = 2e-68
 Identities = 147/341 (43%), Positives = 177/341 (51%), Gaps = 34/341 (9%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G PGPPG  G PGA+G   E G  G  G PGP G +GPPGP G PGP G + + + G++G
Sbjct: 1261 GKPGPPGSTGRPGAEG---EPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRG 1317

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPP------------------GPMGPPGDRGFTGKDG 2848
              G +G AG PG PG  G PG PG P                  GP GP GD G  G+ G
Sbjct: 1318 ATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKG 1377

Query: 2849 AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGR---PGPS---GLKGEKGDRGDIASQN 2902
              G +G  G PG PG  G  GP G PG  G+ G    PGPS   GL G  G  GD+ + +
Sbjct: 1378 QAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYD 1437

Query: 2903 MMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962
             ++   RQ   ++   +M  +   + Q P +  ++  +PGPPG  G PG  GA G P   
Sbjct: 1438 EIKRFIRQEIIKMFDERMAYYTSRM-QFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP--- 1493

Query: 2963 GRPGFPGTPGMQGPPGERGLPGEKGER---GTGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019
            G PG  G  G QG PG RGLPG KGE+   G G +G  GLPGPPGPQG    G  G+TG 
Sbjct: 1494 GLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGP 1553

Query: 3020 RGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYP 3060
             G  G PG PG  G  G PG  G+C+ S C       Q YP
Sbjct: 1554 MGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYP 1594



 Score =  243 bits (619), Expect = 3e-63
 Identities = 144/321 (44%), Positives = 163/321 (50%), Gaps = 49/321 (15%)

Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 2782
            +P +R E   P    S       +GPPG PG  G PG  G +GERG++G     G +G+ 
Sbjct: 1028 LPGQRGEEGPPGMRGS-PGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGL---TGDKGEP 1083

Query: 2783 GPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRG 2842
            GPPG  G PG  GP GL  PG +G +G  G AGE G PG  G+ GLPGPPGP GP G+RG
Sbjct: 1084 GPPGQPGYPGATGPPGL--PGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERG 1141

Query: 2843 FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQN 2902
              G  G  G +G  G PG PG P   GP G PGK G  G PGP   KG +G RG      
Sbjct: 1142 PQGNSGEKGDQGFQGQPGFPGPP---GPPGFPGKVGSPGPPGPQAEKGSEGIRG------ 1192

Query: 2903 MMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962
                                        P+    S   PGPPGPPG  G AG  G  G  
Sbjct: 1193 ----------------------------PSGLPGS---PGPPGPPGIQGPAGLDGLDGKD 1221

Query: 2963 GRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRG 3021
            G+PG  G PG  GPPG  G PG KG+ G  G  GP+G  G PGP G   TG PG+ G  G
Sbjct: 1222 GKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGS--TGRPGAEGEPG 1279

Query: 3022 PPGPPGRPGNSGIRGPPGPPG 3042
              GP GRPG  G  GPPGPPG
Sbjct: 1280 AMGPQGRPGPPGHVGPPGPPG 1300



 Score =  237 bits (605), Expect = 1e-61
 Identities = 142/329 (43%), Positives = 158/329 (48%), Gaps = 74/329 (22%)

Query: 2747 GPPGPPGPAGGPGAKGP------RGERGISGAIGP---PGPRGDIGPPGPQGPPGPQGPN 2797
            G PGPPG  G PGA GP      +GERG +G+ G    PGP G  G PGP GP GP+G  
Sbjct: 1081 GEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGER 1140

Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 2857
            G    G  G +G +G  G+PG PG  G PG PG  G  GPPG +   G +G  GP G PG
Sbjct: 1141 GPQ--GNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPG 1198

Query: 2858 PPGSPGSPGVTGPS------GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQV 2911
             PG PG PG+ GP+      GK GKPG  G PGP+G  G  G                  
Sbjct: 1199 SPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMG------------------ 1240

Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGPPGSA---GARGEPGPG 2962
                               P  ++     PG PGP      PGPPGS    GA GEPG  
Sbjct: 1241 -------------------PPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAM 1281

Query: 2963 GRPGFPGTPGMQGPPGERGLPGE--------KGERG-TGSSGPRGLPGPPGPQGESRTGP 3013
            G  G PG PG  GPPG  G PG         KG+RG TG  G  GLPG PGP G    GP
Sbjct: 1282 GPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG--HPGP 1339

Query: 3014 PGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            PG  G+ G  G  G PG  G  GPPGP G
Sbjct: 1340 PGEPGTDGAAGKEGPPGKQGFYGPPGPKG 1368



 Score =  231 bits (590), Expect = 6e-60
 Identities = 143/341 (41%), Positives = 165/341 (48%), Gaps = 76/341 (22%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGE---------RGISGAIGPPGPRGDIGPPGPQGPPGPQ- 2794
            S G PGPPGPAG  G +GP+G          +G  G  GPPGP G  G  G  GPPGPQ 
Sbjct: 1124 SEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQA 1183

Query: 2795 --------GPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP------MGPPG 2839
                    GP+GL   PG  G  G++G AG  GL G+ G PGL G PGP      MGPPG
Sbjct: 1184 EKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPG 1243

Query: 2840 DRGFTGKDGAMGPRGPPGPPGSPGS---------PGVTGPSGKPGKPGDHGRPGPSGLKG 2890
             +G TG  G  GP+G  G PG PGS         PG  GP G+PG PG  G PGP G  G
Sbjct: 1244 FKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPG 1303

Query: 2891 E--------KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPG 2942
                     KGDRG    + +            + GQ                     PG
Sbjct: 1304 PAGISAVGLKGDRGATGERGLAG----------LPGQ------------------PGPPG 1335

Query: 2943 PPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGP 3002
             PGPPG PG+ GA G+ GP G+ GF G PG +G PG  G  G+ GE+G       G+PG 
Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRA-----GMPGG 1390

Query: 3003 PGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            PG  G     GPPG  G RG PG PG  G+ G+ G PG  G
Sbjct: 1391 PGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMG 1431



 Score =  226 bits (577), Expect = 2e-58
 Identities = 186/620 (30%), Positives = 246/620 (39%), Gaps = 174/620 (28%)

Query: 2561 VNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLS 2620
            V QPT  + P GLP  + ++L   L   T    + ++Q+TD +  PQ+ +  +   ++L 
Sbjct: 84   VTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLE 143

Query: 2621 FFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNI 2680
               +   G+  +  F    V  LF   +HK+ + V  +   +++DC     + +     +
Sbjct: 144  LRAQGQDGDFVSCIF---PVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPM 200

Query: 2681 TTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDI----------PSRRD-- 2728
               G+  LG L   + K  +F +Q   I C P     + CC+I           +RRD  
Sbjct: 201  RPVGHVFLG-LDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDTQ 259

Query: 2729 -----------EGK------CPAFPNSCTCTQDSVG---------------------PP- 2749
                       EGK      C   P +        G                     PP 
Sbjct: 260  SNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPC 319

Query: 2750 -----------GPPGPAGG------PGAKGPRGERGISG----AIGPPGP-RGDIGPPGP 2787
                        P GP GG      PG  G +GE+G  G     I P  P +   GP G 
Sbjct: 320  VHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGE 379

Query: 2788 QGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP---PGPMGPPGDRGF 2843
            +G  G  GP+GL    GE+G++G KGD G  G+PG+ G  G PG     GP G  GD GF
Sbjct: 380  KGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGF 439

Query: 2844 TGKDGAMGPRGPPG---------------PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888
             G +G  G  GPPG               P G PG  G  G SG PGK G  G+PG  G+
Sbjct: 440  VGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGV 499

Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948
            KGEKGD               +VC  L               P  +Q+    PG PGP G
Sbjct: 500  KGEKGD-------------PCEVCPTL---------------PEGFQNFVGLPGKPGPKG 531

Query: 2949 PPGS-AGARGEPGPGGRPGFPGTP----------------------------GMQGPPGE 2979
             PG    ARG+PG  G  G  G P                            G+ G PG 
Sbjct: 532  EPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGR 591

Query: 2980 RGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPP------------ 3026
             G+PG KGE+G  G +GP G PGPPGP      GP G  G++G P  P            
Sbjct: 592  AGVPGLKGEKGNFGEAGPAGSPGPPGP-----VGPAGIKGAKGEPCEPCPALSNLQDGDV 646

Query: 3027 ---GRPGNSGIRGPPGPPGY 3043
                 PG SG +G PGPPG+
Sbjct: 647  RVVALPGPSGEKGEPGPPGF 666



 Score =  223 bits (568), Expect = 2e-57
 Identities = 152/410 (37%), Positives = 187/410 (45%), Gaps = 92/410 (22%)

Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPP-----GPRGDIGP---------PGPQG 2789
            + VG PG PG  G PG +GP G +G+ G  GPP     GP+G+ G          PGP+G
Sbjct: 753  EGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRG 812

Query: 2790 PPGPQ------------------GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 2831
            PPGP                   GP G S+ G  GR G +G  G  G PG  G  G  G 
Sbjct: 813  PPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGE 872

Query: 2832 PGPMGPP--GDRGFTGKDGAMGP-RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888
            PG    P  GD  F+G  GA G   G    PG  G PG+ GP G PG PG  G PG +GL
Sbjct: 873  PGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGL 932

Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQM----------NRFNQMLNQIPN------ 2932
             G+ G   ++ S  + + + + +C   + GQ            + +Q +  +P       
Sbjct: 933  PGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQ 992

Query: 2933 -------------DYQSSRNQP---GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP 2976
                            +S   P   G PG PGPPG  G RGE GP G  G PG PG  GP
Sbjct: 993  CFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGP 1052

Query: 2977 P------GERGLPGEKGERG-TGSSGPRGLPGPPGPQG-ESRTGPP---------GSTGS 3019
            P      G  GLPG +GERG TG +G +G PGPPG  G    TGPP         G TGS
Sbjct: 1053 PGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGS 1112

Query: 3020 RGPPGPPGRPGNSGIRGPPGPPG-------YCDSSQCASIPYNGQ-GYPG 3061
             G  G PG PG+ G+ GPPGP G         +S +     + GQ G+PG
Sbjct: 1113 AGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPG 1162



 Score =  208 bits (529), Expect = 8e-53
 Identities = 135/350 (38%), Positives = 169/350 (48%), Gaps = 51/350 (14%)

Query: 2747 GPPGPPG-----PAGGPGAKGPRGERGISGAIGPPGPRGDIGP---PGPQGPPGPQGPNG 2798
            G PGPPG     P G PGA G  G +G+ G  GPPGP G+ G    PG +G  GP GP G
Sbjct: 780  GEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG 839

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--GDRGFTGKDGAMGP-RGP 2855
             S+ G  GR G +G  G  G PG  G  G  G PG    P  GD  F+G  GA G   G 
Sbjct: 840  ASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGS 899

Query: 2856 PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915
               PG  G PG+ GP G PG PG  G PG +GL G+ G   ++ S  + + + + +C   
Sbjct: 900  SWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDC 959

Query: 2916 ISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG------------PPGSAGARGEPGPGG 2963
            + GQ      ++ +        +   G PG PG             P +  ARG+   G 
Sbjct: 960  VQGQRAHPGYLVEK------GEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGD 1013

Query: 2964 RPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPP 3023
             PG  G+PG+ GPPG   LPG++GE G    G RG PGPPGP      GPPG  G+ G P
Sbjct: 1014 -PGCVGSPGLPGPPG---LPGQRGEEGP--PGMRGSPGPPGP-----IGPPGFPGAVGSP 1062

Query: 3024 GPPGRPGNSGIRG---------PPGPPGYCDSSQCASIP--YNGQGYPGS 3062
            G PG  G  G+ G         PPG PGY  ++    +P     +GY GS
Sbjct: 1063 GLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGS 1112



 Score =  207 bits (528), Expect = 1e-52
 Identities = 138/383 (36%), Positives = 163/383 (42%), Gaps = 119/383 (31%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP---------------------- 2784
            G PG PG AG PG KG +G  G +G  G PGP G +GP                      
Sbjct: 584  GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643

Query: 2785 --------PGPQGPPGPQGPNGLSIPGEQGR------QGMKGDA---GEPGLPGRTGTPG 2827
                    PGP G  G  GP G  +PG+QG+      +G KGDA   G+PG PG TG PG
Sbjct: 644  GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703

Query: 2828 LPGPPGPMGPPGDRG------------------FTGKDGAMGPRGPPGP-----PGSPGS 2864
            L G PG  GP G +G                    G+ G  GP+G  GP     PG PG 
Sbjct: 704  LSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQ 763

Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924
            PG+ G  G PG  G  G PGP G +G +G +G+  +  +                     
Sbjct: 764  PGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGAPGL--------------------- 801

Query: 2925 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG--MQGPPGERGL 2982
                         +  PGP GPPGP G  GA+G PG  G  G  G PG  + GPPG  G 
Sbjct: 802  ----------PGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQ 851

Query: 2983 PGEKGERGT-GSSGPRGLPGPPG-----PQGES-----------------RTGPPGSTGS 3019
             G+ G RGT G  GPRG  G PG      QG+                  + GP G  G 
Sbjct: 852  QGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911

Query: 3020 RGPPGPPGRPGNSGIRGPPGPPG 3042
             GPPGPPG PG  G+ G  G PG
Sbjct: 912  PGPPGPPGVPGLQGVPGNNGLPG 934



 Score =  207 bits (526), Expect = 2e-52
 Identities = 142/391 (36%), Positives = 171/391 (43%), Gaps = 97/391 (24%)

Query: 2742 TQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI----GPPGPQGPPGPQGPN 2797
            T  + G PG  G  G  G  GP+GE+G  G    P  +G +    G PG  GP G QGP 
Sbjct: 695  TPGTTGRPGLSGEPGVQGPAGPKGEKG-DGCTACPSLQGTVTDMAGRPGQPGPKGEQGPE 753

Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP--GPPGPMGPPGDRGFTGKDGAMGPRGP 2855
            G+  PG+ G+ G+ G  G PGL G  G PG P  G  GP G PG  G  G  G  GPRGP
Sbjct: 754  GVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGP 813

Query: 2856 PGP------PGSPGSPGVTGP--------SGKPGKPGDHGRPGPSGLKGEKGDRGDIASQ 2901
            PGP       GSPG  G TGP        SG PG+ G  G+ G  G  GEKG RG+    
Sbjct: 814  PGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEP 873

Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961
                  ++   + + SG        +   P  +  S  QPGP GPPG P      G PGP
Sbjct: 874  GECSCPSQG--DLIFSG--------MPGAPGLWMGSSWQPGPQGPPGIP------GPPGP 917

Query: 2962 GGRPGFPGTPGMQGPPGERGLPGE-------------------KGERG-------TGSSG 2995
             G PG  G PG  G PG+ GL  E                   +G+R         G  G
Sbjct: 918  PGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKG 977

Query: 2996 PRGLPGPPG------------------PQGESRTGPPGSTGSRGPPGPPGRPGN------ 3031
             +G+PG PG                   +G++  G PG  GS G PGPPG PG       
Sbjct: 978  DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037

Query: 3032 SGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
             G+RG PGPPG          P    G+PG+
Sbjct: 1038 PGMRGSPGPPG----------PIGPPGFPGA 1058



 Score =  147 bits (371), Expect = 2e-34
 Identities = 104/285 (36%), Positives = 115/285 (40%), Gaps = 106/285 (37%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802
            Q   GPPGP G  G  G KG  GE+G +G  G PG  G +GP GP GP            
Sbjct: 1358 QGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGP------------ 1405

Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG-------------------------- 2836
                     G+ G PG PG +G+PGLPG PG MG                          
Sbjct: 1406 --------AGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAY 1457

Query: 2837 -------------PPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRP 2883
                          PG  G  GKDGA    G PG PGSPG PG  G  G+ G PG  G P
Sbjct: 1458 YTSRMQFPMEMAAAPGRPGPPGKDGA---PGRPGAPGSPGLPGQIGREGRQGLPGVRGLP 1514

Query: 2884 GPSGLKGEKGDRG-DIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPG 2942
               G KGEKGD G  IA +N +                                    PG
Sbjct: 1515 ---GTKGEKGDIGIGIAGENGL------------------------------------PG 1535

Query: 2943 PPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKG 2987
            PPGP GPPG  G  G  GP G+ G PG P   GPPG  G PG+ G
Sbjct: 1536 PPGPQGPPG-YGKMGATGPMGQQGIPGIP---GPPGPMGQPGKAG 1576



 Score = 85.5 bits (210), Expect = 7e-16
 Identities = 57/135 (42%), Positives = 61/135 (45%), Gaps = 22/135 (16%)

Query: 2735 FPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ 2794
            FP          GPPG  G  G PGA             G PG  G IG  G QG PG +
Sbjct: 1464 FPMEMAAAPGRPGPPGKDGAPGRPGAP------------GSPGLPGQIGREGRQGLPGVR 1511

Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854
            G     +PG +G    KGD G  G+ G  G PG PGP GP G  G  G TG  G  G  G
Sbjct: 1512 G-----LPGTKGE---KGDIG-IGIAGENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPG 1561

Query: 2855 PPGPPGSPGSPGVTG 2869
             PGPPG  G PG  G
Sbjct: 1562 IPGPPGPMGQPGKAG 1576



 Score = 72.0 bits (175), Expect = 8e-12
 Identities = 53/149 (35%), Positives = 66/149 (44%), Gaps = 21/149 (14%)

Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP---- 2983
            ++ P     +R+      P GP G  G RG PGP   PG  G  G +G    R  P    
Sbjct: 314  DECPPCVHGARDSNVTLAPSGPKGGKGERGLPGP---PGSKGEKGARGNDCVRISPDAPL 370

Query: 2984 ----GEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGI---- 3034
                G KGE+G +G+ GP GLPG  G +G+   G  G  G +G PG PGR G  G     
Sbjct: 371  QCAEGPKGEKGESGALGPSGLPGSTGEKGQK--GEKGDGGIKGVPGKPGRDGRPGEICVI 428

Query: 3035 --RGPPGPPGYCDSSQCASIPYNGQGYPG 3061
              +G  G PG+      A  P    G PG
Sbjct: 429  GPKGQKGDPGFVGPEGLAGEP-GPPGLPG 456


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  259 bits (662), Expect = 3e-68
 Identities = 155/346 (44%), Positives = 175/346 (50%), Gaps = 40/346 (11%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--- 2789
            P  P   T      GPPGPPG  G PG  G RGE G  G  GPPGP G +GP GP G   
Sbjct: 950  PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009

Query: 2790 ---------PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 2840
                     PPGP G  GL  PG  G++G KGD G  GLPG+ G PGL G PG  G PG 
Sbjct: 1010 PMGERGHPGPPGPPGEQGL--PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1067

Query: 2841 RGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLK---GEKGD 2894
             G  G  G  GP GPPGP GSPG     G  GP G PG+PG  G PGP+G K   GEKG 
Sbjct: 1068 VGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP 1127

Query: 2895 RGDIASQNMMRAV-----ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP 2949
            +G      +   V     A  V      G      +   +     +  +  PGP GP GP
Sbjct: 1128 QGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP 1187

Query: 2950 ---PGSAGARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGP 2996
               PG +GA GEPGP G+ G           G PG  GP G +GLPG  GE+G TG  G 
Sbjct: 1188 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247

Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             G PGPPGP+G S  G PG+ G +GPPG  G PG  G +G PG  G
Sbjct: 1248 MGPPGPPGPRGPS--GAPGADGPQGPPGGIGNPGAVGEKGEPGEAG 1291



 Score =  256 bits (653), Expect = 3e-67
 Identities = 156/377 (41%), Positives = 174/377 (46%), Gaps = 92/377 (24%)

Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790
            K P  P      Q  VG PGP GP G PG  G +GE G  G  G  G +G+ GPPGP GP
Sbjct: 1125 KGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP 1184

Query: 2791 ------PGPQGPNGLSIP-GEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGP------ 2834
                  PGP G +G   P G+QG  G KGD G    PG PG  G  GLPGPPG       
Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244

Query: 2835 ---MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891
               MGPPG  G  G  GA G  GP GPPG  G+PG  G  G+PG+ G+ G PG  G  G 
Sbjct: 1245 VGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGP 1304

Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951
            KG+RG+        A                                   GPPGP GPPG
Sbjct: 1305 KGERGEKGESGPSGAA----------------------------------GPPGPKGPPG 1330

Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG 3007
              G +G PGP G PG PG PG  GP G+ G PG+KG+ G    TGS GP G PGP GP G
Sbjct: 1331 DDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPG 1390

Query: 3008 E----------------------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCD 3045
            +                         GPPG TG  GP G PG+PG  G+RG PGP G   
Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVG--- 1447

Query: 3046 SSQCASIPYNGQGYPGS 3062
                       QG PGS
Sbjct: 1448 ----------EQGLPGS 1454



 Score =  255 bits (651), Expect = 5e-67
 Identities = 155/352 (44%), Positives = 173/352 (49%), Gaps = 59/352 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP-NGLSIPGEQ 2805
            GPPGP G  G PG  G +GE G  G +GPPGP G  GP G  G  GPQGP  G+  PG  
Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281

Query: 2806 GRQGMKGDAGEPGLPGRTGTPG---------------LPGPPGPMGPPGDRGFTGKDGAM 2850
            G +G  G+AGEPGLPG  G PG                 GPPGP GPPGD G  G  G +
Sbjct: 1282 GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341

Query: 2851 GPRGPPGPPGSPG---------------------SPGVTG---PSGKPGKPGDHGRPGPS 2886
            G  G PGPPG PG                     SPG TG   PSG PGK G  G  GP 
Sbjct: 1342 GFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPE 1401

Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946
            G +GEKG +G+   +         +  Q   G+           P   Q     PGP GP
Sbjct: 1402 GRQGEKGAKGEAGLEGPPGKTG-PIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGP 1460

Query: 2947 PGP---PGSAGARGEPGPGGRPGFPGTPGMQGPPGE------RGLPGEKGERG------- 2990
            PGP   PG  G +G+ GP G  G PG  G+ GPPGE      RGLPG +G  G       
Sbjct: 1461 PGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGI 1520

Query: 2991 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            TG SGP G PGPPG  G    GP G+ GS GP GP G  G+ G  GPPGPPG
Sbjct: 1521 TGPSGPIGPPGPPGLPGPP--GPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  254 bits (648), Expect = 1e-66
 Identities = 148/330 (44%), Positives = 168/330 (50%), Gaps = 57/330 (17%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGD------IGPPG 2786
            P FP +    +   G PG PGP G  G  GPRGERG  G  G PGP+G+       GPPG
Sbjct: 888  PGFPGA-NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPG 946

Query: 2787 PQGPPGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 2845
             +GP GPQGP G   P G  G  G  G  G PG  G TG  G  GPPGP G  G +G TG
Sbjct: 947  ERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTG 1006

Query: 2846 KDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD------HGRPGPSGLKGEKGDRGDIA 2899
            + G MG RG PGPPG PG  G+ G +GK G  GD       G+ GP GL+G  GDRG   
Sbjct: 1007 ETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRG--- 1063

Query: 2900 SQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP 2959
                            + G +       N+            GPPGPPGP GS G RG  
Sbjct: 1064 ----------------LPGPVGALGLKGNE------------GPPGPPGPAGSPGERGPA 1095

Query: 2960 GPGGRPGFPGTPGMQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTG 3012
            G  G  G PG PG QGPP   GE+G PGEKG +G     G  GP GLPGP GP      G
Sbjct: 1096 GAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP-----VG 1150

Query: 3013 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            PPG  G +G  G PG+ G+ G +G  GPPG
Sbjct: 1151 PPGEDGDKGEIGEPGQKGSKGDKGEQGPPG 1180



 Score =  251 bits (641), Expect = 8e-66
 Identities = 150/347 (43%), Positives = 167/347 (48%), Gaps = 36/347 (10%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G PGPPGP G  G  GP GE+G +G +G  GP G  GP GP G PG  GP G   PG  G
Sbjct: 1219 GFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP--PGGIG 1276

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866
              G  G+ GEPG  G  G PG  GPPGP G  G++G +G  GA GP GP GPPG  G  G
Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336

Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926
              GP G PG PG  G PGP+G  G  GD+GD        +      E   SG   +    
Sbjct: 1337 SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG-PTGEPGPSGPPGKRGPP 1395

Query: 2927 LNQIPNDYQSSRNQP---------------GPPGPPGPPGSAGARGEPGPGGRPGFPGTP 2971
                P   Q  +                  GP G PG PG  G RG PGP G  G PG+P
Sbjct: 1396 GPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSP 1455

Query: 2972 GMQGPPGER---GLPGEKGERG----TGSSGPRGLPGPPGPQGE----------SRTGPP 3014
            G  GPPG     GLPG KG+ G     G  G  GL GPPG QGE            +GP 
Sbjct: 1456 GPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK 1515

Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            G  G  GP GP G PG  G+ GPPGP G   SS     P    G+PG
Sbjct: 1516 GEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTG-PKGEAGHPG 1561



 Score =  242 bits (618), Expect = 4e-63
 Identities = 148/348 (42%), Positives = 173/348 (49%), Gaps = 50/348 (14%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGA---IGPPGPRGDIGPPGPQGPPGPQGPNGLS--- 2800
            GP GP G  G PG  GP G  G+ G    +GP GPRG  GPPGP G PG +G  G     
Sbjct: 559  GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618

Query: 2801 -IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------ 2853
             +PG+ G +G +G  G  GLPG  G  G PGP GP GPPGD G  G DG +GPR      
Sbjct: 619  GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678

Query: 2854 ------GPPGPPGSPGSPGVTGPSGKPGKPGD---HGRPGPSGLKGEKGDRGDIASQNMM 2904
                  GP GPPG PG PGVTG  G+PG  G+    G PGP G +G  G +G    Q  +
Sbjct: 679  GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAI 738

Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR 2964
                 +       G + +    L  +P     +   PG PG  GPPG  G +G PGP G 
Sbjct: 739  GPPGEK-------GPLGK--PGLPGMP----GADGPPGHPGKEGPPGEKGGQGPPGPQGP 785

Query: 2965 PGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SRTGP 3013
             G+PG  G++G  G RGL G KGE+G           G  G RG  GPPGP+GE    GP
Sbjct: 786  IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP 845

Query: 3014 PGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             G  G  G PGP G PG  G  G PG PGY         P    G+PG
Sbjct: 846  KGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQG----PKGSIGFPG 889



 Score =  239 bits (611), Expect = 2e-62
 Identities = 137/315 (43%), Positives = 158/315 (50%), Gaps = 46/315 (14%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNGLSIPGE 2804
            +GP GPPGP G P         G++G  G PGP+G++GP G  GPPG QG P    +PG 
Sbjct: 684  LGPKGPPGPPGPP---------GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGP 734

Query: 2805 QGR---QGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGS 2861
            QG     G KG  G+PGLPG  G  G PG PG  GPPG++G  G  G  GP G PGP G 
Sbjct: 735  QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794

Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921
             G+ G+ G  G  G+ G+ G PG  G  G KGDRG+I                   G   
Sbjct: 795  KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEI-------------------GPPG 835

Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------GPGGRPGFPGTPGMQG 2975
               +   + P         PGP GPPG  G  G  G P      GP G  GFPG PG  G
Sbjct: 836  PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895

Query: 2976 PPGERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPG 3027
              G RG PG+ G RG        G  GPRG+ G PGP+G S   GP G  G RGP GP G
Sbjct: 896  EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQG 955

Query: 3028 RPGNSGIRGPPGPPG 3042
              G  G +GPPGPPG
Sbjct: 956  PTGFPGPKGPPGPPG 970



 Score =  239 bits (610), Expect = 3e-62
 Identities = 141/328 (42%), Positives = 165/328 (50%), Gaps = 32/328 (9%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP------------PGPQGPPGPQ 2794
            G  G  G  G PG KG  G +G  G IGPPGPRG+ GP            PGP GPPG +
Sbjct: 805  GTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK 864

Query: 2795 GPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853
            G  G+  +PG  GRQG KG  G PG PG  G  G  G PG  GP G RG TG  G  GPR
Sbjct: 865  GKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPR 924

Query: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR--QV 2911
            G  G PG  G+ G  GP+G PG+ G +G  GP+G  G KG  G      +     +  + 
Sbjct: 925  GITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984

Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP---------GSAGARGEPGPG 2962
              Q  +G       +  Q P        + G PGPPGPP         G  G +G+PGP 
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044

Query: 2963 GRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE----SRTGP---P 3014
            G PG  G PG++G PG+RGLPG  G  G  G+ GP G PGP G  GE       GP   P
Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104

Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G  G +GPPGP G  G  G +GP GP G
Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAG 1132



 Score =  235 bits (600), Expect = 4e-61
 Identities = 147/362 (40%), Positives = 167/362 (46%), Gaps = 74/362 (20%)

Query: 2743 QDSVGPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799
            Q ++GPPG  GP G    PG  G  G  G  G  GPPG +G  GPPGPQGP G  GP G+
Sbjct: 735  QGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGV 794

Query: 2800 -------------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP--------- 2831
                                 PG +G  G+KGD GE G PG  G  G  GP         
Sbjct: 795  KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854

Query: 2832 PGPMGPPGDR------GFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885
            PGP+GPPG++      G  G  G  GP+G  G PG PG+ G  G  G PGKPG  G+ GP
Sbjct: 855  PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914

Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPG 2945
            +G +GE+G RG          +  +   +  SG          + PN  Q     PGP G
Sbjct: 915  TGPRGERGPRG----------ITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKG 964

Query: 2946 PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGP 3005
            PPGPPG  G  G PG  G  GF G  G  GPPG  G  G  GE  TG  G RG PGPPGP
Sbjct: 965  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE--TGPMGERGHPGPPGP 1022

Query: 3006 QGE----------------------SRTGPP---GSTGSRGPPGPPGRPGNSGIRGPPGP 3040
             GE                       + GPP   G  G RG PGP G  G  G  GPPGP
Sbjct: 1023 PGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP 1082

Query: 3041 PG 3042
            PG
Sbjct: 1083 PG 1084



 Score =  233 bits (594), Expect = 2e-60
 Identities = 151/354 (42%), Positives = 167/354 (47%), Gaps = 62/354 (17%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISG---AIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800
            G PGP G  G PG KGP G+ G+ G   A GPPG  G  GPPG    QGPPGPQGP G  
Sbjct: 730  GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789

Query: 2801 IP-------GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853
             P       G +G +G KG+ GE G PG  G  G+ G  G +GPPG RG  G +G  G  
Sbjct: 790  GPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRG 849

Query: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS---------GLKGEKGDRGDIASQNMM 2904
            GP G PG  G PG  G  G PG PG  GR GP          G  GEKG RG        
Sbjct: 850  GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRG-------- 901

Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGPPGSAGARGE 2958
                         G+     Q     P   +  R   G PGP       GP G  G RG 
Sbjct: 902  -----------TPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950

Query: 2959 PGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP---GPQGES-RTGP 3013
             GP G  GFPG  G  GPPG+ GLPG  G+RG TG  G  G PGPP   GPQG +  TGP
Sbjct: 951  NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP 1010

Query: 3014 PGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             G  G  GPPGPPG        G  G +G PGP G          P   +G+PG
Sbjct: 1011 MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDG----PPGLRGFPG 1060



 Score =  202 bits (515), Expect = 3e-51
 Identities = 134/346 (38%), Positives = 153/346 (44%), Gaps = 74/346 (21%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-------- 2798
            GPPGP GPAG PG   P G  G +G +G PG RG  G PG  G  G  GP G        
Sbjct: 469  GPPGPEGPAGLPG---PPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFR 525

Query: 2799 -----------------------------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP 2829
                                         L++ G  G  G+ G  G  G PG  G  G P
Sbjct: 526  FGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEP 585

Query: 2830 GPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGP---------SGKPGKPGDH 2880
            G  GP GP G +G  G  G  G RG  G  G+ G PG TGP         +G PG+ G  
Sbjct: 586  GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHR 645

Query: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQ 2940
            G PGPSG  G  GD G+       R    +V  + + G+               +     
Sbjct: 646  GDPGPSGPPGPPGDDGE-------RGDDGEVGPRGLPGEPGP------------RGLLGP 686

Query: 2941 PGPPGPPGPPGSAGARGEPGPGGR---PGFPGTPGMQGPPGERGLPGEKGERG-TGSSGP 2996
             GPPGPPGPPG  G  G+PGP G     G PG PG QG PG +GLPG +G  G  G  GP
Sbjct: 687  KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP 746

Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             G PG PG  G    GPPG  G  GPPG  G  G  G +GP G PG
Sbjct: 747  LGKPGLPGMPGAD--GPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790



 Score =  199 bits (506), Expect = 3e-50
 Identities = 116/245 (47%), Positives = 131/245 (53%), Gaps = 33/245 (13%)

Query: 2747 GPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            GPPG PGPAG    PG KG  GE G +G+ GP G  G  GPPG +GPPGP GP G     
Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEG----- 1402

Query: 2804 EQGRQGMKGDAGEPGLPGRTG------TPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 2857
             QG +G KG+AG  G PG+TG       PG PGP G  G PG  G  G  G+ GP GPPG
Sbjct: 1403 RQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462

Query: 2858 PPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914
            P G PG PG+   +GP G+ G PG  G  GP G +GEKGDRG    Q           EQ
Sbjct: 1463 PMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKG----EQ 1518

Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 2974
             I+G            P+        PG PGPPGP G+ G+ G  GP G  G PG PG  
Sbjct: 1519 GITG------------PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPP 1566

Query: 2975 GPPGE 2979
            GPPGE
Sbjct: 1567 GPPGE 1571



 Score =  175 bits (443), Expect = 7e-43
 Identities = 138/395 (34%), Positives = 160/395 (40%), Gaps = 95/395 (24%)

Query: 2728 DEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGA--------IGPPGPR 2779
            D G     P S   T +S  P  PPG  G    +G   E  I             P    
Sbjct: 369  DPGAGAEIPTSTADTSNSSNPAPPPGE-GADDLEGEFTEETIRNLDENYYDPYYDPTSSP 427

Query: 2780 GDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAG--EPGLPGRTGTPGLPGPPGPMGP 2837
             +IGP    G P  Q      I G +G +G KG+    EPG+        + GPPGP GP
Sbjct: 428  SEIGP----GMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML-------IEGPPGPEGP 476

Query: 2838 PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG----LKGEKG 2893
                      G  GP G  GP G  G PG  GP G+PG PG  G PGP G    L    G
Sbjct: 477  A---------GLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527

Query: 2894 DRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI------PNDYQSSRNQPGPPGPP 2947
              GD  S+  M           +S Q ++   +L Q       P        +PGP GPP
Sbjct: 528  GGGDAGSKGPM-----------VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP 576

Query: 2948 ------------GPPGSAGARGEPGPGGRP---------GFPGTPGMQGPPGER------ 2980
                        GP G  G +G PGP G+P         G  G PG  GP G+R      
Sbjct: 577  GSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLA 636

Query: 2981 GLPGEKGERGTGSSGPRGLPGPPGPQGE-------------SRTGPPGSTGSRGPPGPPG 3027
            GLPGEKG R  G  GP G PGPPG  GE                GP G  G +GPPGPPG
Sbjct: 637  GLPGEKGHR--GDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPG 694

Query: 3028 RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
             PG +G+ G PGP G     Q    P   QG PG+
Sbjct: 695  PPGVTGMDGQPGPKGNV-GPQGEPGPPGQQGNPGA 728



 Score =  151 bits (381), Expect = 1e-35
 Identities = 94/244 (38%), Positives = 104/244 (42%), Gaps = 86/244 (35%)

Query: 2745 SVGPPGPPGPAGGPGAKGP---------RGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 2795
            S GP G PGP+G PG +GP         +GE+G  G  G  GP G  GP GPQG PG  G
Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435

Query: 2796 PNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPG---------------------PPG 2833
            P+GL  IPG  G QG+ G  G  G PG  G PGLPG                     PPG
Sbjct: 1436 PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPG 1495

Query: 2834 PMGPPGDRGFTGKDGAMGPRG------PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSG 2887
              G  GDRG  G  G+ GP+G      P GP G PG PG+ GP   PG  G  G  GP+G
Sbjct: 1496 EQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGP---PGPKGAKGSSGPTG 1552

Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 2947
             KGE G                                               PGPPGPP
Sbjct: 1553 PKGEAG----------------------------------------------HPGPPGPP 1566

Query: 2948 GPPG 2951
            GPPG
Sbjct: 1567 GPPG 1570



 Score =  104 bits (259), Expect = 2e-21
 Identities = 61/128 (47%), Positives = 69/128 (53%), Gaps = 20/128 (15%)

Query: 2747 GPPGPPGPAGGPGAKG---PRGERG---ISGAIGPPGP---RGDIGPPGPQGPPGPQGPN 2797
            GPPGP GP G PG KG   P+GE+G   + G IGPPG    +GD G PGPQG  GP+G  
Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ 1518

Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPG 2857
            G++  G  G  G  G  G PG PG  G  G  GP GP          G+ G  GP GPPG
Sbjct: 1519 GIT--GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGP---------KGEAGHPGPPGPPG 1567

Query: 2858 PPGSPGSP 2865
            PPG    P
Sbjct: 1568 PPGEVIQP 1575



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 46/95 (48%), Positives = 50/95 (52%), Gaps = 14/95 (14%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQ 2805
            +GPPG  G  G  G  GP+G  G  G  G  GP G IGPPGP G PGP GP G    G  
Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAK--GSS 1548

Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 2840
            G  G KG+AG             PGPPGP GPPG+
Sbjct: 1549 GPTGPKGEAGH------------PGPPGPPGPPGE 1571



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 34/74 (45%), Positives = 41/74 (55%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802
            Q   GP GP GP G PG  GP G +G  G+ GP GP+G+ G PGP GPPGP G     +P
Sbjct: 1518 QGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577

Query: 2803 GEQGRQGMKGDAGE 2816
             +  R     DA +
Sbjct: 1578 IQASRTRRNIDASQ 1591



 Score = 33.9 bits (76), Expect = 2.5
 Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 7/146 (4%)

Query: 2522 KMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHP-NGLPPSYTII 2580
            K+L+ +NL +    +    +    S     AYR+ K+A ++ PT  L+P +  P  ++I+
Sbjct: 44   KVLDFHNLPDGITKTTGFCATRRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSIL 103

Query: 2581 LLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEV 2640
               +   +  S  F +  I +     Q+G+      ++  F  +D  G+     +     
Sbjct: 104  TTVK--AKKGSQAFLV-SIYNEQGIQQIGL---ELGRSPVFLYEDHTGKPGPEDYPLFRG 157

Query: 2641 KTLFYGSFHKVHIVVTSKSVKIYIDC 2666
              L  G +H++ + V  K+V + +DC
Sbjct: 158  INLSDGKWHRIALSVHKKNVTLILDC 183


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  254 bits (650), Expect = 7e-67
 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 2794
            GPPGPPG  G PG  G RGE G  G  GPPGP G +GP GP G            PPGP 
Sbjct: 946  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 1005

Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854
            G  GL  PG  G++G KGD G  G+ G+ G  GL G PG  G PG +G  G  G  GP+G
Sbjct: 1006 GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1063

Query: 2855 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 2907
            PPGP GSP   GS G  GP G PG+PG  G PGP+G K   GEKG +G      +   V 
Sbjct: 1064 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1123

Query: 2908 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 2954
                   A    E    G++    Q         +  + + GPPGPP      G PG AG
Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1177

Query: 2955 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004
              GEPGP G+ G           G PG  GP G +GLPG  GE+G  G  GP G PGPPG
Sbjct: 1178 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237

Query: 3005 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            P+G       +   GPPGS GS G  G  G PG +G  GPPG  G
Sbjct: 1238 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282



 Score =  249 bits (635), Expect = 4e-65
 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%)

Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790
            K P  P      Q  VG PGP GPAG PG  G +GE G  G  G  G +G+ GPPGP G 
Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166

Query: 2791 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 2833
             GP G  G++     PG +G+QGM G  G+      PG PG  G  GLPGPPG       
Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1226

Query: 2834 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891
              PMGPPG  G  G  G  G  GP GPPGS GS G  G  G+PG+ G+ G PG +G+ G 
Sbjct: 1227 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1286

Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951
            KG+RG+        A          +G         +  P         PG PGPPG PG
Sbjct: 1287 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336

Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 3009
             AG  G  G  G  G PG PG  GP GE G PG  G+RG  G++G  G  G  G +GE+ 
Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1396

Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              GPPG TG  GP GP G+PG  G+RG PGP G
Sbjct: 1397 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1429



 Score =  242 bits (618), Expect = 4e-63
 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805
            GPPGP G  G PG  G +GE G  G +GPPGP G  GP GP G  GPQGP G +   G  
Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1263

Query: 2806 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 2850
            G +G  G+AG PG PG  G                PG  GPPG  GPPGD G  G  G +
Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323

Query: 2851 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 2888
            G  G PGPPG PG                   PG  GPSG+ G PG  G+ GP G     
Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383

Query: 2889 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 2941
              +GEKG +G+  ++         V  Q  +G+     + L  IP          +  Q 
Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1440

Query: 2942 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 2997
            GPPGP GPPG  G +G+PG  G  G PG  G+ GPPGE+G  G++G  GT    G+ G  
Sbjct: 1441 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1500

Query: 2998 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G+PGP GP G        GP G  G++G  GP G+ G+SG+ GPPG PG
Sbjct: 1501 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549



 Score =  239 bits (611), Expect = 2e-62
 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%)

Query: 2746 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 2798
            +GP G PG AG  G  GPR      G+ G++G  GPPGP+G++GP G  GPPG QG P  
Sbjct: 651  IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 710

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 2858
              +PG QG  G  G+ G  G PG  G PG  GPP   G PG  G +G+ GA+GP GP GP
Sbjct: 711  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 767

Query: 2859 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 2918
             G PG  GV G  G  G  G  G  G  G  G KGD G                   + G
Sbjct: 768  IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 808

Query: 2919 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 2978
                  Q+  +  +  +  + + GP G PGP G AG +G+ G    PG PG PG QGP G
Sbjct: 809  DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 865

Query: 2979 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037
              G PG  G    G  G RG+ G PGP+G+   TGP GS G+RGP G PG  G SG  GP
Sbjct: 866  STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923

Query: 3038 PGPPGYCDSSQCASIPYNGQGYPG 3061
            PGPPG     +    P    G+PG
Sbjct: 924  PGPPG----ERGPQGPQGPVGFPG 943



 Score =  239 bits (611), Expect = 2e-62
 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P  P      +   G PGP G +GG G  GP GERG      P GP+G +G PGP+GPPG
Sbjct: 896  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 949

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
            P        PG+ G  G  G  GE G  G+TG PG  G  GP GP G+ G  G+ G  GP
Sbjct: 950  P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001

Query: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 2912
             GPPG  G PG+ G  G  G PG  G  G+ GP+GL+G  G+RG   +Q           
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1052

Query: 2913 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 2972
                                     +   GP GPPGP GS G RG  G  G  G PG PG
Sbjct: 1053 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1090

Query: 2973 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 3025
             QGPP   GE+G PGEKG +G     G  GP GLPGP GP G    G  G  G  G PG 
Sbjct: 1091 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1148

Query: 3026 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             G  G+ G  GPPGPPG         I   G G PG
Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1183



 Score =  239 bits (609), Expect = 4e-62
 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%)

Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 2796
            GPPGP      PGP GGPG+ G +GE   SG  GP GPRG  GPPGP G PG +G     
Sbjct: 541  GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597

Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856
             G  +PGE G +G +G  G PGLPG  G  G  GP GP GPPGD G  G+DG +GPRG P
Sbjct: 598  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 657

Query: 2857 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
                     GP G+PG+PG  G +G  G PG  G  GP G  G  G +G+   Q      
Sbjct: 658  GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 712

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 2961
                    + G          + P         PG  GPPG PG  G  GE      PGP
Sbjct: 713  --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 764

Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 3010
             G  G+PG  G++G  G RGL G KGE+G           G  G RG  G  GP+GE   
Sbjct: 765  QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 824

Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             GP G  G  G PGP G+ G  G  G PG PGY         P    G+PG
Sbjct: 825  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 871



 Score =  227 bits (579), Expect = 1e-58
 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 2777
            ++GPPGP GP G PG +G +G  G+ G                            +G  G
Sbjct: 758  ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 817

Query: 2778 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 2822
            PRG+ GP GP+G  GP G  G S             +PG  GRQG KG  G PG PG   
Sbjct: 818  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 877

Query: 2823 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 2869
                    G PG  G  GP GP G RG  G  G  GP+      GPPGPPG  G  G  G
Sbjct: 878  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 937

Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 2927
            P G PG  G  G PG  GL G  G RG+   Q           V  Q  +G+     +  
Sbjct: 938  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 995

Query: 2928 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 2981
                      R  PGPPGPPG    PG+A   GA+G+PGP G  G  G  G++G PGERG
Sbjct: 996  ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 1045

Query: 2982 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 3033
            LPG +G  G  G  GP+G PGP   PG +G + T    G PG  G +GPPGP G  G  G
Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105

Query: 3034 IRGPPGPPG 3042
             +GP GP G
Sbjct: 1106 EKGPQGPAG 1114



 Score =  224 bits (571), Expect = 1e-57
 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 2791
            GPPGP G  G  G  GP G++G  G  G PGP+G IGPPG   PQG            PP
Sbjct: 685  GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 744

Query: 2792 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835
                           GP GP G +  PG +G +G  G  G  G  G  G  G PG  G M
Sbjct: 745  GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 804

Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895
            G  GDRG  G+ G  G  GP GP G  G  G  GPSG+ G+ G  G PG  G  G +G +
Sbjct: 805  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864

Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 2949
            G         A   +     ++G+     Q     P   + +R   G PGP       GP
Sbjct: 865  GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923

Query: 2950 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 3002
            PG  G RG  GP G  GFPG  G  GPPG+ GLPG  G+RG       TG  GP G+ GP
Sbjct: 924  PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983

Query: 3003 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 3056
             GP GE  TGP G  G  GPPGPPG        G  G +G PGP G       A +    
Sbjct: 984  QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 1037

Query: 3057 QGYPG 3061
            +G+PG
Sbjct: 1038 RGFPG 1042



 Score =  210 bits (534), Expect = 2e-53
 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%)

Query: 2747 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 2794
            GPPGP GPAG    PG +GP G  G  G  GPPG  G  G  G  GPPG           
Sbjct: 454  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 513

Query: 2795 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844
             G  G +I  +         Q R  ++G  G  GL GR G  G PG  G  G  GD G  
Sbjct: 514  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 573

Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 2901
            G  G  GP GP G PG  G PG  G  G PG+P   GD G  G  GL G+KG RG+   Q
Sbjct: 574  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 633

Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961
                                         P      R + G  GP G PG AG RG  GP
Sbjct: 634  GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 668

Query: 2962 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 3007
             G PG PG PGM    GPPG +G  G +GE G     G+ GP+GLPGP GP G       
Sbjct: 669  RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728

Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            + + G  G  G+ GPPG PG+ G SG +G  GPPG          P    GYPG
Sbjct: 729  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 772



 Score =  201 bits (512), Expect = 7e-51
 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GPPG PGPAG  G  G +GE G  G  GPPGP G+ GPPGP G  GP G  G    G QG
Sbjct: 1330 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1387

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 2863
             +G KG+AG  G PG+TG  G  GP G  GP G RG     G+ G  G  G  GPPG  G
Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447

Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923
             PG+ G  G PG  G+ G PG  GL G  G++G+                          
Sbjct: 1448 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1481

Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983
                       +  R  PG  G PG  G  G  G  GP G PG PG PG QGP G +G  
Sbjct: 1482 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530

Query: 2984 GEKGERG-TGSSGPRGLPGPPG 3004
            G  G++G +G  GP G PGPPG
Sbjct: 1531 GPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  177 bits (449), Expect = 1e-43
 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%)

Query: 2748 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 2799
            P  PP    GPG  A+    E  I+G  A G  G +G+  +  PG   +GPPGP GP G+
Sbjct: 405  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859
                                    G PGL GP GP G PGDRG  G+ G  G  G PGPP
Sbjct: 465  M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 501

Query: 2860 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 2886
            G+           GS G T                       GP G  G+PG  G PG S
Sbjct: 502  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 561

Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946
            G KGE GD G    +              + G      +   +        R  PG PG 
Sbjct: 562  GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 608

Query: 2947 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 2994
                     PG PG  G RGE GP G PG PG  GM+G  GE   RGLPGE G RG    
Sbjct: 609  KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 666

Query: 2995 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 3042
            GPRG PG PG  G +   GPPG  G+ GP   PGPPG+ GN G +G PGP G
Sbjct: 667  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718



 Score =  137 bits (346), Expect = 1e-31
 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 2798
            GP G PGP G  G  GP GE+G+ GA G   PPGP G  G PG +G PG +G  G     
Sbjct: 1411 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1470

Query: 2799 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856
              +  PGEQG +G +G  G  G PG  G  G+PGP GP+GPPG  G  G  G  G +G  
Sbjct: 1471 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530

Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885
            GP G  G  G+ GP G PG PG+  +P P
Sbjct: 1531 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559



 Score =  130 bits (327), Expect = 2e-29
 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            + G  GPPGP G PG  G +G+ G  G  G PG  G IGPPG QG  G +G     +PG 
Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1490

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
            QG  G KGD G PG  G  G PG PG PGP GP G++G TG  G  G  G PGPPGSPG 
Sbjct: 1491 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1550

Query: 2865 PG 2866
            PG
Sbjct: 1551 PG 1552



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 2778
            +GPPG PG  G PG+KG +G  G+ G IGPPG                           P
Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1505

Query: 2779 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 2838
             G +GPPGP G PGPQGP G    G  G  G KGD+G P      G PG PGPPG +  P
Sbjct: 1506 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1557



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%)

Query: 2933 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 2976
            +Y+   ++P  PP     PG P             GA GE G  G P     PGM  +GP
Sbjct: 397  EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 455

Query: 2977 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 3036
            PG               +GP G+ GPPG QG   TGPPG  G R      G PG  G+ G
Sbjct: 456  PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 493

Query: 3037 PPGPPGYCDSSQCASIPYNGQGYPG 3061
              G PG   +       Y G G  G
Sbjct: 494  ADGLPGPPGTMLMLPFRYGGDGSKG 518



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%)

Query: 2536 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 2588
            S +G+S  +G       S  S +AYR+ K A ++ PT  L P G  P     +LF + P+
Sbjct: 50   SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108

Query: 2589 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 2648
                 F +  I +     Q+GV      ++  F  +D  G+     +       +  G +
Sbjct: 109  KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164

Query: 2649 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 2706
            H+V I V  K+V + +DC +   K  D  E   + T+G  + G  +  E       IQ F
Sbjct: 165  HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223

Query: 2707 DIVCSP 2712
             I   P
Sbjct: 224  LITGDP 229


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  254 bits (650), Expect = 7e-67
 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 2794
            GPPGPPG  G PG  G RGE G  G  GPPGP G +GP GP G            PPGP 
Sbjct: 895  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954

Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854
            G  GL  PG  G++G KGD G  G+ G+ G  GL G PG  G PG +G  G  G  GP+G
Sbjct: 955  GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012

Query: 2855 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 2907
            PPGP GSP   GS G  GP G PG+PG  G PGP+G K   GEKG +G      +   V 
Sbjct: 1013 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072

Query: 2908 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 2954
                   A    E    G++    Q         +  + + GPPGPP      G PG AG
Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1126

Query: 2955 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004
              GEPGP G+ G           G PG  GP G +GLPG  GE+G  G  GP G PGPPG
Sbjct: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186

Query: 3005 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            P+G       +   GPPGS GS G  G  G PG +G  GPPG  G
Sbjct: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231



 Score =  249 bits (635), Expect = 4e-65
 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%)

Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790
            K P  P      Q  VG PGP GPAG PG  G +GE G  G  G  G +G+ GPPGP G 
Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115

Query: 2791 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 2833
             GP G  G++     PG +G+QGM G  G+      PG PG  G  GLPGPPG       
Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1175

Query: 2834 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891
              PMGPPG  G  G  G  G  GP GPPGS GS G  G  G+PG+ G+ G PG +G+ G 
Sbjct: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1235

Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951
            KG+RG+        A          +G         +  P         PG PGPPG PG
Sbjct: 1236 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285

Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 3009
             AG  G  G  G  G PG PG  GP GE G PG  G+RG  G++G  G  G  G +GE+ 
Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1345

Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              GPPG TG  GP GP G+PG  G+RG PGP G
Sbjct: 1346 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1378



 Score =  242 bits (618), Expect = 4e-63
 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805
            GPPGP G  G PG  G +GE G  G +GPPGP G  GP GP G  GPQGP G +   G  
Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1212

Query: 2806 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 2850
            G +G  G+AG PG PG  G                PG  GPPG  GPPGD G  G  G +
Sbjct: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272

Query: 2851 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 2888
            G  G PGPPG PG                   PG  GPSG+ G PG  G+ GP G     
Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332

Query: 2889 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 2941
              +GEKG +G+  ++         V  Q  +G+     + L  IP          +  Q 
Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1389

Query: 2942 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 2997
            GPPGP GPPG  G +G+PG  G  G PG  G+ GPPGE+G  G++G  GT    G+ G  
Sbjct: 1390 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1449

Query: 2998 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G+PGP GP G        GP G  G++G  GP G+ G+SG+ GPPG PG
Sbjct: 1450 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498



 Score =  239 bits (611), Expect = 2e-62
 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%)

Query: 2746 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 2798
            +GP G PG AG  G  GPR      G+ G++G  GPPGP+G++GP G  GPPG QG P  
Sbjct: 600  IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 2858
              +PG QG  G  G+ G  G PG  G PG  GPP   G PG  G +G+ GA+GP GP GP
Sbjct: 660  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 716

Query: 2859 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 2918
             G PG  GV G  G  G  G  G  G  G  G KGD G                   + G
Sbjct: 717  IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 757

Query: 2919 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 2978
                  Q+  +  +  +  + + GP G PGP G AG +G+ G    PG PG PG QGP G
Sbjct: 758  DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 814

Query: 2979 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037
              G PG  G    G  G RG+ G PGP+G+   TGP GS G+RGP G PG  G SG  GP
Sbjct: 815  STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872

Query: 3038 PGPPGYCDSSQCASIPYNGQGYPG 3061
            PGPPG     +    P    G+PG
Sbjct: 873  PGPPG----ERGPQGPQGPVGFPG 892



 Score =  239 bits (611), Expect = 2e-62
 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P  P      +   G PGP G +GG G  GP GERG      P GP+G +G PGP+GPPG
Sbjct: 845  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 898

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
            P        PG+ G  G  G  GE G  G+TG PG  G  GP GP G+ G  G+ G  GP
Sbjct: 899  P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950

Query: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 2912
             GPPG  G PG+ G  G  G PG  G  G+ GP+GL+G  G+RG   +Q           
Sbjct: 951  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1001

Query: 2913 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 2972
                                     +   GP GPPGP GS G RG  G  G  G PG PG
Sbjct: 1002 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1039

Query: 2973 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 3025
             QGPP   GE+G PGEKG +G     G  GP GLPGP GP G    G  G  G  G PG 
Sbjct: 1040 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1097

Query: 3026 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             G  G+ G  GPPGPPG         I   G G PG
Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1132



 Score =  239 bits (609), Expect = 4e-62
 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%)

Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 2796
            GPPGP      PGP GGPG+ G +GE   SG  GP GPRG  GPPGP G PG +G     
Sbjct: 490  GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546

Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856
             G  +PGE G +G +G  G PGLPG  G  G  GP GP GPPGD G  G+DG +GPRG P
Sbjct: 547  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 606

Query: 2857 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
                     GP G+PG+PG  G +G  G PG  G  GP G  G  G +G+   Q      
Sbjct: 607  GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 661

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 2961
                    + G          + P         PG  GPPG PG  G  GE      PGP
Sbjct: 662  --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 713

Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 3010
             G  G+PG  G++G  G RGL G KGE+G           G  G RG  G  GP+GE   
Sbjct: 714  QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 773

Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             GP G  G  G PGP G+ G  G  G PG PGY         P    G+PG
Sbjct: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 820



 Score =  227 bits (579), Expect = 1e-58
 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 2777
            ++GPPGP GP G PG +G +G  G+ G                            +G  G
Sbjct: 707  ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 766

Query: 2778 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 2822
            PRG+ GP GP+G  GP G  G S             +PG  GRQG KG  G PG PG   
Sbjct: 767  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826

Query: 2823 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 2869
                    G PG  G  GP GP G RG  G  G  GP+      GPPGPPG  G  G  G
Sbjct: 827  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 886

Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 2927
            P G PG  G  G PG  GL G  G RG+   Q           V  Q  +G+     +  
Sbjct: 887  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 944

Query: 2928 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 2981
                      R  PGPPGPPG    PG+A   GA+G+PGP G  G  G  G++G PGERG
Sbjct: 945  ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 994

Query: 2982 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 3033
            LPG +G  G  G  GP+G PGP   PG +G + T    G PG  G +GPPGP G  G  G
Sbjct: 995  LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054

Query: 3034 IRGPPGPPG 3042
             +GP GP G
Sbjct: 1055 EKGPQGPAG 1063



 Score =  224 bits (571), Expect = 1e-57
 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 2791
            GPPGP G  G  G  GP G++G  G  G PGP+G IGPPG   PQG            PP
Sbjct: 634  GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693

Query: 2792 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835
                           GP GP G +  PG +G +G  G  G  G  G  G  G PG  G M
Sbjct: 694  GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753

Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895
            G  GDRG  G+ G  G  GP GP G  G  G  GPSG+ G+ G  G PG  G  G +G +
Sbjct: 754  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813

Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 2949
            G         A   +     ++G+     Q     P   + +R   G PGP       GP
Sbjct: 814  GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872

Query: 2950 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 3002
            PG  G RG  GP G  GFPG  G  GPPG+ GLPG  G+RG       TG  GP G+ GP
Sbjct: 873  PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932

Query: 3003 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 3056
             GP GE  TGP G  G  GPPGPPG        G  G +G PGP G       A +    
Sbjct: 933  QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 986

Query: 3057 QGYPG 3061
            +G+PG
Sbjct: 987  RGFPG 991



 Score =  210 bits (534), Expect = 2e-53
 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%)

Query: 2747 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 2794
            GPPGP GPAG    PG +GP G  G  G  GPPG  G  G  G  GPPG           
Sbjct: 403  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 462

Query: 2795 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844
             G  G +I  +         Q R  ++G  G  GL GR G  G PG  G  G  GD G  
Sbjct: 463  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 522

Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 2901
            G  G  GP GP G PG  G PG  G  G PG+P   GD G  G  GL G+KG RG+   Q
Sbjct: 523  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 582

Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961
                                         P      R + G  GP G PG AG RG  GP
Sbjct: 583  GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 617

Query: 2962 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 3007
             G PG PG PGM    GPPG +G  G +GE G     G+ GP+GLPGP GP G       
Sbjct: 618  RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677

Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            + + G  G  G+ GPPG PG+ G SG +G  GPPG          P    GYPG
Sbjct: 678  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 721



 Score =  201 bits (512), Expect = 7e-51
 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GPPG PGPAG  G  G +GE G  G  GPPGP G+ GPPGP G  GP G  G    G QG
Sbjct: 1279 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1336

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 2863
             +G KG+AG  G PG+TG  G  GP G  GP G RG     G+ G  G  G  GPPG  G
Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396

Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923
             PG+ G  G PG  G+ G PG  GL G  G++G+                          
Sbjct: 1397 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1430

Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983
                       +  R  PG  G PG  G  G  G  GP G PG PG PG QGP G +G  
Sbjct: 1431 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479

Query: 2984 GEKGERG-TGSSGPRGLPGPPG 3004
            G  G++G +G  GP G PGPPG
Sbjct: 1480 GPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  177 bits (449), Expect = 1e-43
 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%)

Query: 2748 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 2799
            P  PP    GPG  A+    E  I+G  A G  G +G+  +  PG   +GPPGP GP G+
Sbjct: 354  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859
                                    G PGL GP GP G PGDRG  G+ G  G  G PGPP
Sbjct: 414  M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 450

Query: 2860 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 2886
            G+           GS G T                       GP G  G+PG  G PG S
Sbjct: 451  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 510

Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946
            G KGE GD G    +              + G      +   +        R  PG PG 
Sbjct: 511  GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 557

Query: 2947 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 2994
                     PG PG  G RGE GP G PG PG  GM+G  GE   RGLPGE G RG    
Sbjct: 558  KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 615

Query: 2995 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 3042
            GPRG PG PG  G +   GPPG  G+ GP   PGPPG+ GN G +G PGP G
Sbjct: 616  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667



 Score =  137 bits (346), Expect = 1e-31
 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 2798
            GP G PGP G  G  GP GE+G+ GA G   PPGP G  G PG +G PG +G  G     
Sbjct: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1419

Query: 2799 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856
              +  PGEQG +G +G  G  G PG  G  G+PGP GP+GPPG  G  G  G  G +G  
Sbjct: 1420 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479

Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885
            GP G  G  G+ GP G PG PG+  +P P
Sbjct: 1480 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508



 Score =  130 bits (327), Expect = 2e-29
 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            + G  GPPGP G PG  G +G+ G  G  G PG  G IGPPG QG  G +G     +PG 
Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1439

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
            QG  G KGD G PG  G  G PG PG PGP GP G++G TG  G  G  G PGPPGSPG 
Sbjct: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1499

Query: 2865 PG 2866
            PG
Sbjct: 1500 PG 1501



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 2778
            +GPPG PG  G PG+KG +G  G+ G IGPPG                           P
Sbjct: 1395 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1454

Query: 2779 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 2838
             G +GPPGP G PGPQGP G    G  G  G KGD+G P      G PG PGPPG +  P
Sbjct: 1455 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1506



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%)

Query: 2933 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 2976
            +Y+   ++P  PP     PG P             GA GE G  G P     PGM  +GP
Sbjct: 346  EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 404

Query: 2977 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 3036
            PG               +GP G+ GPPG QG   TGPPG  G R      G PG  G+ G
Sbjct: 405  PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 442

Query: 3037 PPGPPGYCDSSQCASIPYNGQGYPG 3061
              G PG   +       Y G G  G
Sbjct: 443  ADGLPGPPGTMLMLPFRYGGDGSKG 467



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%)

Query: 2536 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 2588
            S +G+S  +G       S  S +AYR+ K A ++ PT  L P G  P     +LF + P+
Sbjct: 50   SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108

Query: 2589 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 2648
                 F +  I +     Q+GV      ++  F  +D  G+     +       +  G +
Sbjct: 109  KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164

Query: 2649 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 2706
            H+V I V  K+V + +DC +   K  D  E   + T+G  + G  +  E       IQ F
Sbjct: 165  HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223

Query: 2707 DIVCSP 2712
             I   P
Sbjct: 224  LITGDP 229


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  254 bits (650), Expect = 7e-67
 Identities = 152/345 (44%), Positives = 174/345 (50%), Gaps = 57/345 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG------------PPGPQ 2794
            GPPGPPG  G PG  G RGE G  G  GPPGP G +GP GP G            PPGP 
Sbjct: 934  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993

Query: 2795 GPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854
            G  GL  PG  G++G KGD G  G+ G+ G  GL G PG  G PG +G  G  G  GP+G
Sbjct: 994  GEQGL--PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051

Query: 2855 PPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLK---GEKGDRGDIASQNMMRAV- 2907
            PPGP GSP   GS G  GP G PG+PG  G PGP+G K   GEKG +G      +   V 
Sbjct: 1052 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111

Query: 2908 -------ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP------GPPGSAG 2954
                   A    E    G++    Q         +  + + GPPGPP      G PG AG
Sbjct: 1112 LPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGPPGLQGPVGAPGIAG 1165

Query: 2955 ARGEPGPGGRPGF---------PGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPG 3004
              GEPGP G+ G           G PG  GP G +GLPG  GE+G  G  GP G PGPPG
Sbjct: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225

Query: 3005 PQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            P+G       +   GPPGS GS G  G  G PG +G  GPPG  G
Sbjct: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270



 Score =  249 bits (635), Expect = 4e-65
 Identities = 146/333 (43%), Positives = 170/333 (51%), Gaps = 31/333 (9%)

Query: 2731 KCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP 2790
            K P  P      Q  VG PGP GPAG PG  G +GE G  G  G  G +G+ GPPGP G 
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154

Query: 2791 PGPQGPNGLS----IPGEQGRQGMKGDAGE------PGLPGRTGTPGLPGPPG------- 2833
             GP G  G++     PG +G+QGM G  G+      PG PG  G  GLPGPPG       
Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD 1214

Query: 2834 --PMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891
              PMGPPG  G  G  G  G  GP GPPGS GS G  G  G+PG+ G+ G PG +G+ G 
Sbjct: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1274

Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951
            KG+RG+        A          +G         +  P         PG PGPPG PG
Sbjct: 1275 KGERGEKGEAGPPGA----------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324

Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES- 3009
             AG  G  G  G  G PG PG  GP GE G PG  G+RG  G++G  G  G  G +GE+ 
Sbjct: 1325 PAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAG 1384

Query: 3010 RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              GPPG TG  GP GP G+PG  G+RG PGP G
Sbjct: 1385 AEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417



 Score =  242 bits (618), Expect = 4e-63
 Identities = 144/349 (41%), Positives = 174/349 (49%), Gaps = 56/349 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPGEQ 2805
            GPPGP G  G PG  G +GE G  G +GPPGP G  GP GP G  GPQGP G +   G  
Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1251

Query: 2806 GRQGMKGDAGEPGLPGRTGT---------------PGLPGPPGPMGPPGDRGFTGKDGAM 2850
            G +G  G+AG PG PG  G                PG  GPPG  GPPGD G  G  G +
Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311

Query: 2851 GPRGPPGPPGSPG------------------SPGVTGPSGKPGKPGDHGRPGPSGL---- 2888
            G  G PGPPG PG                   PG  GPSG+ G PG  G+ GP G     
Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371

Query: 2889 --KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY-----QSSRNQP 2941
              +GEKG +G+  ++         V  Q  +G+     + L  IP          +  Q 
Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTG-PVGPQGPAGKPGP--EGLRGIPGPVGEQGLPGAAGQD 1428

Query: 2942 GPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPR 2997
            GPPGP GPPG  G +G+PG  G  G PG  G+ GPPGE+G  G++G  GT    G+ G  
Sbjct: 1429 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1488

Query: 2998 GLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G+PGP GP G        GP G  G++G  GP G+ G+SG+ GPPG PG
Sbjct: 1489 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537



 Score =  239 bits (611), Expect = 2e-62
 Identities = 138/324 (42%), Positives = 165/324 (50%), Gaps = 39/324 (12%)

Query: 2746 VGPPGPPGPAGGPGAKGPR------GERGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNG 2798
            +GP G PG AG  G  GPR      G+ G++G  GPPGP+G++GP G  GPPG QG P  
Sbjct: 639  IGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP 2858
              +PG QG  G  G+ G  G PG  G PG  GPP   G PG  G +G+ GA+GP GP GP
Sbjct: 699  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---GHPGKEGQSGEKGALGPPGPQGP 755

Query: 2859 PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISG 2918
             G PG  GV G  G  G  G  G  G  G  G KGD G                   + G
Sbjct: 756  IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG-------------------LKG 796

Query: 2919 QMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPG 2978
                  Q+  +  +  +  + + GP G PGP G AG +G+ G    PG PG PG QGP G
Sbjct: 797  DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV---PGLPGYPGRQGPKG 853

Query: 2979 ERGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGP 3037
              G PG  G    G  G RG+ G PGP+G+   TGP GS G+RGP G PG  G SG  GP
Sbjct: 854  STGFPGFPG--ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911

Query: 3038 PGPPGYCDSSQCASIPYNGQGYPG 3061
            PGPPG     +    P    G+PG
Sbjct: 912  PGPPG----ERGPQGPQGPVGFPG 931



 Score =  239 bits (611), Expect = 2e-62
 Identities = 140/336 (41%), Positives = 159/336 (47%), Gaps = 55/336 (16%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P  P      +   G PGP G +GG G  GP GERG      P GP+G +G PGP+GPPG
Sbjct: 884  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG------PQGPQGPVGFPGPKGPPG 937

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
            P        PG+ G  G  G  GE G  G+TG PG  G  GP GP G+ G  G+ G  GP
Sbjct: 938  P--------PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989

Query: 2853 RGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVC 2912
             GPPG  G PG+ G  G  G PG  G  G+ GP+GL+G  G+RG   +Q           
Sbjct: 990  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA--------- 1040

Query: 2913 EQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG 2972
                                     +   GP GPPGP GS G RG  G  G  G PG PG
Sbjct: 1041 ----------------------PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1078

Query: 2973 MQGPP---GERGLPGEKGERG----TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGP 3025
             QGPP   GE+G PGEKG +G     G  GP GLPGP GP G    G  G  G  G PG 
Sbjct: 1079 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQ 1136

Query: 3026 PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             G  G+ G  GPPGPPG         I   G G PG
Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIA-GGDGEPG 1171



 Score =  239 bits (609), Expect = 4e-62
 Identities = 146/351 (41%), Positives = 168/351 (47%), Gaps = 56/351 (15%)

Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG----P 2796
            GPPGP      PGP GGPG+ G +GE   SG  GP GPRG  GPPGP G PG +G     
Sbjct: 529  GPPGPMGLTGRPGPVGGPGSSGAKGE---SGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585

Query: 2797 NGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856
             G  +PGE G +G +G  G PGLPG  G  G  GP GP GPPGD G  G+DG +GPRG P
Sbjct: 586  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 645

Query: 2857 ---------GPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
                     GP G+PG+PG  G +G  G PG  G  GP G  G  G +G+   Q      
Sbjct: 646  GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG----- 700

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGE------PGP 2961
                    + G          + P         PG  GPPG PG  G  GE      PGP
Sbjct: 701  --------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 752

Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE-SR 3010
             G  G+PG  G++G  G RGL G KGE+G           G  G RG  G  GP+GE   
Sbjct: 753  QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 812

Query: 3011 TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             GP G  G  G PGP G+ G  G  G PG PGY         P    G+PG
Sbjct: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG----PKGSTGFPG 859



 Score =  227 bits (579), Expect = 1e-58
 Identities = 146/369 (39%), Positives = 171/369 (46%), Gaps = 83/369 (22%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGA---------------------------IGPPG 2777
            ++GPPGP GP G PG +G +G  G+ G                            +G  G
Sbjct: 746  ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 805

Query: 2778 PRGDIGPPGPQGPPGPQGPNGLS-------------IPGEQGRQGMKGDAGEPGLPGR-- 2822
            PRG+ GP GP+G  GP G  G S             +PG  GRQG KG  G PG PG   
Sbjct: 806  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865

Query: 2823 -------TGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR------GPPGPPGSPGSPGVTG 2869
                    G PG  G  GP GP G RG  G  G  GP+      GPPGPPG  G  G  G
Sbjct: 866  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 925

Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM--RAVARQVCEQLISGQMNRFNQML 2927
            P G PG  G  G PG  GL G  G RG+   Q           V  Q  +G+     +  
Sbjct: 926  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-- 983

Query: 2928 NQIPNDYQSSRNQPGPPGPPGP---PGSA---GARGEPGPGGRPGFPGTPGMQGPPGERG 2981
                      R  PGPPGPPG    PG+A   GA+G+PGP G  G  G  G++G PGERG
Sbjct: 984  ----------RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 1033

Query: 2982 LPGEKGERG-TGSSGPRGLPGP---PGPQGESRT----GPPGSTGSRGPPGPPGRPGNSG 3033
            LPG +G  G  G  GP+G PGP   PG +G + T    G PG  G +GPPGP G  G  G
Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093

Query: 3034 IRGPPGPPG 3042
             +GP GP G
Sbjct: 1094 EKGPQGPAG 1102



 Score =  224 bits (571), Expect = 1e-57
 Identities = 144/365 (39%), Positives = 168/365 (46%), Gaps = 57/365 (15%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPG---PQG------------PP 2791
            GPPGP G  G  G  GP G++G  G  G PGP+G IGPPG   PQG            PP
Sbjct: 673  GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732

Query: 2792 ---------------GPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835
                           GP GP G +  PG +G +G  G  G  G  G  G  G PG  G M
Sbjct: 733  GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 792

Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895
            G  GDRG  G+ G  G  GP GP G  G  G  GPSG+ G+ G  G PG  G  G +G +
Sbjct: 793  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852

Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PGP 2949
            G         A   +     ++G+     Q     P   + +R   G PGP       GP
Sbjct: 853  GSTGFPGFPGANGEKGARG-VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911

Query: 2950 PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSGPRGLPGP 3002
            PG  G RG  GP G  GFPG  G  GPPG+ GLPG  G+RG       TG  GP G+ GP
Sbjct: 912  PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971

Query: 3003 PGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPGYCDSSQCASIPYNG 3056
             GP GE  TGP G  G  GPPGPPG        G  G +G PGP G       A +    
Sbjct: 972  QGPTGE--TGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---- 1025

Query: 3057 QGYPG 3061
            +G+PG
Sbjct: 1026 RGFPG 1030



 Score =  210 bits (534), Expect = 2e-53
 Identities = 140/354 (39%), Positives = 158/354 (44%), Gaps = 74/354 (20%)

Query: 2747 GPPGPPGPAG---GPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQ--------- 2794
            GPPGP GPAG    PG +GP G  G  G  GPPG  G  G  G  GPPG           
Sbjct: 442  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGG 501

Query: 2795 -GPNGLSIPGE---------QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844
             G  G +I  +         Q R  ++G  G  GL GR G  G PG  G  G  GD G  
Sbjct: 502  DGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQ 561

Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKP---GDHGRPGPSGLKGEKGDRGDIASQ 2901
            G  G  GP GP G PG  G PG  G  G PG+P   GD G  G  GL G+KG RG+   Q
Sbjct: 562  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 621

Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961
                                         P      R + G  GP G PG AG RG  GP
Sbjct: 622  GPPG-------------------------PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 656

Query: 2962 GGRPGFPGTPGM---QGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG------- 3007
             G PG PG PGM    GPPG +G  G +GE G     G+ GP+GLPGP GP G       
Sbjct: 657  RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716

Query: 3008 ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            + + G  G  G+ GPPG PG+ G SG +G  GPPG          P    GYPG
Sbjct: 717  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG----------PQGPIGYPG 760



 Score =  201 bits (512), Expect = 7e-51
 Identities = 112/262 (42%), Positives = 128/262 (48%), Gaps = 43/262 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GPPG PGPAG  G  G +GE G  G  GPPGP G+ GPPGP G  GP G  G    G QG
Sbjct: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--GRQG 1375

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF---TGKDGAMGPRGPPGPPGSPG 2863
             +G KG+AG  G PG+TG  G  GP G  GP G RG     G+ G  G  G  GPPG  G
Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435

Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923
             PG+ G  G PG  G+ G PG  GL G  G++G+                          
Sbjct: 1436 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-------------------------- 1469

Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983
                       +  R  PG  G PG  G  G  G  GP G PG PG PG QGP G +G  
Sbjct: 1470 -----------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518

Query: 2984 GEKGERG-TGSSGPRGLPGPPG 3004
            G  G++G +G  GP G PGPPG
Sbjct: 1519 GPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  177 bits (449), Expect = 1e-43
 Identities = 132/352 (37%), Positives = 151/352 (42%), Gaps = 95/352 (26%)

Query: 2748 PPGPPGPAGGPG--AKGPRGERGISG--AIGPPGPRGD--IGPPGP--QGPPGPQGPNGL 2799
            P  PP    GPG  A+    E  I+G  A G  G +G+  +  PG   +GPPGP GP G+
Sbjct: 393  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859
                                    G PGL GP GP G PGDRG  G+ G  G  G PGPP
Sbjct: 453  M-----------------------GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPP 489

Query: 2860 GS----------PGSPGVT-----------------------GPSGKPGKPGDHGRPGPS 2886
            G+           GS G T                       GP G  G+PG  G PG S
Sbjct: 490  GTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSS 549

Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946
            G KGE GD G    +              + G      +   +        R  PG PG 
Sbjct: 550  GAKGESGDPGPQGPRG-------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 596

Query: 2947 ---------PGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE---RGLPGEKGERGTGSS 2994
                     PG PG  G RGE GP G PG PG  GM+G  GE   RGLPGE G RG    
Sbjct: 597  KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--L 654

Query: 2995 GPRGLPGPPGPQGESRT-GPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPG 3042
            GPRG PG PG  G +   GPPG  G+ GP   PGPPG+ GN G +G PGP G
Sbjct: 655  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706



 Score =  137 bits (346), Expect = 1e-31
 Identities = 70/149 (46%), Positives = 83/149 (55%), Gaps = 10/149 (6%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG---PPGPRGDIGPPGPQGPPGPQGPNG----- 2798
            GP G PGP G  G  GP GE+G+ GA G   PPGP G  G PG +G PG +G  G     
Sbjct: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1458

Query: 2799 --LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPP 2856
              +  PGEQG +G +G  G  G PG  G  G+PGP GP+GPPG  G  G  G  G +G  
Sbjct: 1459 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518

Query: 2857 GPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885
            GP G  G  G+ GP G PG PG+  +P P
Sbjct: 1519 GPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547



 Score =  130 bits (327), Expect = 2e-29
 Identities = 65/122 (53%), Positives = 72/122 (59%), Gaps = 5/122 (4%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            + G  GPPGP G PG  G +G+ G  G  G PG  G IGPPG QG  G +G     +PG 
Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRG-----LPGT 1478

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
            QG  G KGD G PG  G  G PG PG PGP GP G++G TG  G  G  G PGPPGSPG 
Sbjct: 1479 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1538

Query: 2865 PG 2866
            PG
Sbjct: 1539 PG 1540



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 51/120 (42%), Positives = 58/120 (48%), Gaps = 35/120 (29%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------------------------P 2778
            +GPPG PG  G PG+KG +G  G+ G IGPPG                           P
Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1493

Query: 2779 RGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP 2838
             G +GPPGP G PGPQGP G    G  G  G KGD+G P      G PG PGPPG +  P
Sbjct: 1494 AGPLGPPGPPGLPGPQGPKGNK--GSTGPAGQKGDSGLP------GPPGSPGPPGEVIQP 1545



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 49/145 (33%), Positives = 58/145 (40%), Gaps = 39/145 (26%)

Query: 2933 DYQSSRNQP-GPPGP---PGPPGSA----------GARGEPGPGGRPGFPGTPGM--QGP 2976
            +Y+   ++P  PP     PG P             GA GE G  G P     PGM  +GP
Sbjct: 385  EYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-EPGMLVEGP 443

Query: 2977 PGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRG 3036
            PG               +GP G+ GPPG QG   TGPPG  G R      G PG  G+ G
Sbjct: 444  PGP--------------AGPAGIMGPPGLQGP--TGPPGDPGDR------GPPGRPGLPG 481

Query: 3037 PPGPPGYCDSSQCASIPYNGQGYPG 3061
              G PG   +       Y G G  G
Sbjct: 482  ADGLPGPPGTMLMLPFRYGGDGSKG 506



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 15/186 (8%)

Query: 2536 SVQGVSLESG-------SFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPE 2588
            S +G+S  +G       S  S +AYR+ K A ++ PT  L P G  P     +LF + P+
Sbjct: 50   SPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPE-DFSILFTVKPK 108

Query: 2589 TPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSF 2648
                 F +  I +     Q+GV      ++  F  +D  G+     +       +  G +
Sbjct: 109  KGIQSFLL-SIYNEHGIQQIGV---EVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164

Query: 2649 HKVHIVVTSKSVKIYIDCYEIIEK--DIKEAGNITTDGYEILGKLLKGERKSAAFQIQSF 2706
            H+V I V  K+V + +DC +   K  D  E   + T+G  + G  +  E       IQ F
Sbjct: 165  HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEG-DIQQF 223

Query: 2707 DIVCSP 2712
             I   P
Sbjct: 224  LITGDP 229


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  254 bits (649), Expect = 9e-67
 Identities = 165/405 (40%), Positives = 185/405 (45%), Gaps = 88/405 (21%)

Query: 2743 QDSVGPPGPPGPA-----GGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPN 2797
            Q   G PGPPGP+     G PG  G  GERG  G  G  GP G  GP GP GPPG  GP 
Sbjct: 91   QGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPA 150

Query: 2798 GLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLP--------------------------GP 2831
            G+S+PG+ G+QG  G  G  G PG  G PG+P                          GP
Sbjct: 151  GISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGP 210

Query: 2832 PGPMGPP-----------------GDRGFTGKDGAMGPRGPPGPP--------------G 2860
             GP GPP                 GDRGF G+ G +GP GP GPP              G
Sbjct: 211  TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270

Query: 2861 SPGSPGVTGPSGKPGKPGDHGRPGP-----SGLKGEKGDRGDIASQNMMRAVARQVCEQL 2915
            +PG PG+ G  G PG PG  G PGP      GL G KG+RG         A   Q    L
Sbjct: 271  APGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGL 330

Query: 2916 IS--GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP------PGSAGARGEPGPGGRPGF 2967
                G       M  Q P     S   PGP G  GP      PG+ G RG PG  G+PG+
Sbjct: 331  PGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGY 390

Query: 2968 PGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG-------ESRTGP---PGST 3017
            PG PG+ GP G  GLPG KG+ G G  GP GLPGP GP G           GP   PG  
Sbjct: 391  PGKPGLDGPKGNPGLPGPKGDPGVG--GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIP 448

Query: 3018 GSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG-QGYPG 3061
            G+RGP GPPG PG  G +G PG PG    +  A+   NG  G PG
Sbjct: 449  GTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPG 493



 Score =  244 bits (622), Expect = 1e-63
 Identities = 144/328 (43%), Positives = 158/328 (48%), Gaps = 51/328 (15%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGP------PGPRGDIGPPGPQGPPGPQGPNGLS 2800
            GP GP GP+G PG  G RGE G+ G  G       PG  G IGPPGPQGPPG +GP G+ 
Sbjct: 206  GPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIG 264

Query: 2801 IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPG-----------PMGPPGDRGFTGKDGA 2849
             PG  G  G  G  G  GLPG  G  G PGPPG             GP G  G  G  G 
Sbjct: 265  KPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGE 324

Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP---------SGLKGEKGDRGDIAS 2900
             GP G PG PG  G PG  GP G  G PG HG PGP         +G  G KG+RG   S
Sbjct: 325  QGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGS 384

Query: 2901 QNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG 2960
                        +    G+        N      +      GPPG PGP G AGA+G PG
Sbjct: 385  DG----------KPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPG 434

Query: 2961 ------PGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPP 3014
                  P G PG PGT G  GPPG  G PG KG+ G+        PGPPGP G +  G  
Sbjct: 435  HNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS--------PGPPGPAGIATKGLN 486

Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G TG  GPPGP G  G  G+ GPPGPPG
Sbjct: 487  GPTGPPGPPGPRGHSGEPGLPGPPGPPG 514



 Score =  235 bits (599), Expect = 6e-61
 Identities = 153/358 (42%), Positives = 176/358 (49%), Gaps = 63/358 (17%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPP--GPQGPNGL- 2799
            Q + GPPGP GP G PG  GP G+ G     G PG +G+ G PGP GP   G  G  GL 
Sbjct: 59   QGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPSAVGKPGVPGLP 114

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--PPGDRGFTGKDGAMGPRGPPG 2857
              PGE+G  G KGD G  GLPG  G PG PG PGP G   PG  G  G  GA GPRG PG
Sbjct: 115  GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174

Query: 2858 PPGSPGSPGVTGPSGK-----PGKPGDHGRPGPSGLKGEKGDRG-DIASQNMMRAVARQV 2911
              G+PG PG+ G  G+     PG+PG+ G PGP G  G  G  G     +N +       
Sbjct: 175  EKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIK 234

Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP--------GPPGSAGARGEPGPGG 2963
             ++   G+M                    PGP GPP        G PG+AGA G+PG  G
Sbjct: 235  GDRGFPGEMGPI---------------GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPG 279

Query: 2964 RPGFPGTPGMQGPP-----GERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE 3008
              G PG PG+ GPP     G+ GLPG KGERG           G  GP GLPG PG    
Sbjct: 280  TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG---- 335

Query: 3009 SRTGPPGSTGSRGP---PGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNG--QGYPG 3061
              TGPPG+ G +GP   PG  G PG  G  GP GP GY  +      P +    GYPG
Sbjct: 336  -LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392



 Score =  223 bits (569), Expect = 2e-57
 Identities = 130/286 (45%), Positives = 146/286 (51%), Gaps = 37/286 (12%)

Query: 2767 RGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTP 2826
            RG  G  GPPGP G  G PGP GPPG     G   PG QG  G+ G  G P   G+ G P
Sbjct: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKP---GYGSPGLQGEPGLPGPPG-PSAVGKPGVP 111

Query: 2827 GLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPS 2886
            GLPG PG  GP G +G  G  G  GPRGPPGPPG PG  G++ P GKPG+ G  G PGP 
Sbjct: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGPR 170

Query: 2887 GLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP 2946
            G  GEKG  G                   + G   +  +M    P      R  PGP GP
Sbjct: 171  GFPGEKGAPG-------------------VPGMNGQKGEMGYGAPG-RPGERGLPGPQGP 210

Query: 2947 PGP--PGSAGARGEPGPGGRP------GFPGTPGMQGPPGERGLPGEKGERGTGSSGPRG 2998
             GP  P   G RGE G  G+P      GFPG  G  GPPG +G PGE+G  G G  G  G
Sbjct: 211  TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270

Query: 2999 LPGPPGPQGESRTGPPGSTGSRGPPGPP--GRPGNSGIRGPPGPPG 3042
             PG PG  G    G PG+ G  GPPGPP  G+PG  G++G  GP G
Sbjct: 271  APGQPGIPGTK--GLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAG 314



 Score =  186 bits (473), Expect = 2e-46
 Identities = 123/318 (38%), Positives = 142/318 (44%), Gaps = 68/318 (21%)

Query: 2742 TQDSVGPPGPPGPA-----GGPGAKGPRGERGISGAIGPPGPRGDIGP------PGPQGP 2790
            T+   G PG  GP      G PG  G +GERG +G  G PG +G+ GP      PG  GP
Sbjct: 280  TKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGP 339

Query: 2791 P---GPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGF 2843
            P   GPQGP G+     +PG +G  G  G AG PG  G  G+PG  G PG  G PG  G 
Sbjct: 340  PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP 399

Query: 2844 TGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM 2903
             G  G  GP+G PG  G PG PG  GP+G  G PG +G  GP G  G  G RG I     
Sbjct: 400  KGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI----- 454

Query: 2904 MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGG 2963
                                                  GPPG PG PGS G  G PGP G
Sbjct: 455  --------------------------------------GPPGIPGFPGSKGDPGSPGPPG 476

Query: 2964 RPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPP 3023
              G   T G+ GP G  G PG +G   +G  G  G PGPPGP G++   P G   +   P
Sbjct: 477  PAGI-ATKGLNGPTGPPGPPGPRGH--SGEPGLPGPPGPPGPPGQA-VMPEGFIKAGQRP 532

Query: 3024 GPPGRP---GNSGIRGPP 3038
               G P    N G+ G P
Sbjct: 533  SLSGTPLVSANQGVTGMP 550



 Score =  136 bits (342), Expect = 4e-31
 Identities = 90/258 (34%), Positives = 103/258 (39%), Gaps = 59/258 (22%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P  P     +    GP G  GPAG  G  G +GERG  G+ G PG  G  G  GP+G PG
Sbjct: 345  PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG 404

Query: 2793 PQGPNG-------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTG 2845
              GP G         +PG  G  G KG  G  G  G  G PG+PG  GP+GPPG  GF G
Sbjct: 405  LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG 464

Query: 2846 KDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905
              G  G  GPPGP G   + G+ GP+G PG PG  G  G  GL G  G            
Sbjct: 465  SKGDPGSPGPPGPAGI-ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPG------------ 511

Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 2965
                                                 PPGPPG   +    G    G RP
Sbjct: 512  -------------------------------------PPGPPGQ--AVMPEGFIKAGQRP 532

Query: 2966 GFPGTPGMQGPPGERGLP 2983
               GTP +    G  G+P
Sbjct: 533  SLSGTPLVSANQGVTGMP 550



 Score =  133 bits (334), Expect = 3e-30
 Identities = 92/216 (42%), Positives = 106/216 (49%), Gaps = 27/216 (12%)

Query: 2843 FTGKDGAMGPRGPPGPPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIA 2899
            +T K   +  RG  G PG PG  G     GPSG PGKPG +G PG  G  G  G  G   
Sbjct: 46   YTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGP-- 102

Query: 2900 SQNMMRAVARQVCEQLIS--GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA--GA 2955
                  AV +     L    G+   +    +  P      R  PGPPG PGP G +  G 
Sbjct: 103  -----SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGK 157

Query: 2956 RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGS---SGPRGLPGPPGPQGESRTG 3012
             G+ GP G PG  G PG +G PG  G+ G+KGE G G+    G RGLPGP GP G S  G
Sbjct: 158  PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPS--G 215

Query: 3013 PPGSTGSRGPPGPPGRPGNSGIR------GPPGPPG 3042
            PPG  G RG  G PG+PG  G R      GP GPPG
Sbjct: 216  PPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250



 Score = 42.0 bits (97), Expect = 0.009
 Identities = 17/29 (58%), Positives = 19/29 (65%)

Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043
            G  G+ GPPGP G  G+ G  GPPG PGY
Sbjct: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY 85


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  253 bits (647), Expect = 2e-66
 Identities = 148/337 (43%), Positives = 175/337 (51%), Gaps = 40/337 (11%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGER---GISGAIGPP------------- 2776
            P  P      +  VGPPGP G AG  GA G RGE    G +G  GPP             
Sbjct: 793  PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852

Query: 2777 --GPRGDIGPPGPQGP---PGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830
              G +GD G PGPQGP   PGPQGP G++ P G +G QG  G  G PG  GR G PG  G
Sbjct: 853  EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 912

Query: 2831 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890
             PGP GPPG    +GKDG  G RG  GPPG  G PG+ GP+G PG+ G+ G  GPSG +G
Sbjct: 913  NPGPPGPPGP---SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969

Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950
              G +G +A Q  +  +  Q  E+   G            P+     +  PG  G  GPP
Sbjct: 970  PPGPQG-LAGQRGIVGLPGQRGERGFPGLPG---------PSGEPGKQGAPGASGDRGPP 1019

Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES 3009
            G  G  G  GP G PG  G+PG  GPPG  G  G KG+RG TG+ G  G PGPPG  G +
Sbjct: 1020 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1079

Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
                + G  G  G++GP GP G  G  GI+GP GP G
Sbjct: 1080 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116



 Score =  248 bits (634), Expect = 5e-65
 Identities = 146/335 (43%), Positives = 166/335 (49%), Gaps = 60/335 (17%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GPPGPPGP+G  G KG RG+ G  G  G PG +G  GPPG +G PG  GP+G    G  G
Sbjct: 915  GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE--GPPG 972

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866
             QG+ G  G  GLPG+ G  G PG PGP G PG +G     GA G RGPPGP G PG  G
Sbjct: 973  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---APGASGDRGPPGPVGPPGLTG 1029

Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926
              G  G+ G PG  G PG  G  G KGDRG+  +     A                    
Sbjct: 1030 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-------------------- 1069

Query: 2927 LNQIPNDYQSSRNQPGPPGPPGPPG---------SAGARGEPGPGGRPGFPGTPGMQGPP 2977
                          PGPPG PGP G          AGA+G  GP G  G  G  G QGP 
Sbjct: 1070 --------------PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1115

Query: 2978 GERGLPGEKGERGT----GSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPGNS 3032
            G++G  GE GERG     G +G +GLPGPPGP G+   +GP G +G RGPPGP G  G  
Sbjct: 1116 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1175

Query: 3033 GIRG------PPGPPGYCDSSQCASIPYNGQGYPG 3061
            G  G      PPGP G    +  A  P N  G PG
Sbjct: 1176 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG 1209



 Score =  248 bits (633), Expect = 7e-65
 Identities = 150/360 (41%), Positives = 177/360 (49%), Gaps = 70/360 (19%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP----------------- 2785
            Q  VGP G PG  G PG  GP+G RG  G +G PGP+G  G P                 
Sbjct: 572  QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631

Query: 2786 -------GPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEP---------GLPGRTGT 2825
                   G  GPPGP GP G       PG  G QG+ G  G P         G+PG  G 
Sbjct: 632  PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691

Query: 2826 PGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP---GKPGDHGR 2882
            PGL GP G  G PG+RG  G  G  GPRG PG PG+ G  G +GP+G P   G PG  G 
Sbjct: 692  PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751

Query: 2883 P---GPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939
            P   G +G+ G KGDRGD+  +    A  +     L +G +          P     +  
Sbjct: 752  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIG---------PPGPAGANG 801

Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TG 2992
            + G  GPPGP GSAGARG PG  G  G PG  G  GPPG  G PG KGE+G        G
Sbjct: 802  EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861

Query: 2993 SSGPRGLPGPPGPQGESR-TGPPGSTGSRGPPGPP---------GRPGNSGIRGPPGPPG 3042
            + GP+G  G PGPQG +  TGP G+ G++GPPG           G PG++G  GPPGPPG
Sbjct: 862  APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921



 Score =  243 bits (619), Expect = 3e-63
 Identities = 172/477 (36%), Positives = 204/477 (42%), Gaps = 122/477 (25%)

Query: 2672 KDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGK 2731
            +D++EAG+   DG     K +            +  ++C  +     + C  P       
Sbjct: 26   QDVQEAGSCVQDGQRYNDKDVWKPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGEC 85

Query: 2732 CPAFPNSCTCT----------------QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP 2775
            CP  P                      +D VGP GPPGP G  G +GPRG+RG  G  G 
Sbjct: 86   CPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145

Query: 2776 PGPRG---------DIGPPGPQGPPGP---------------------------QGPNG- 2798
            PGPRG         + GPPGP GPPGP                           QGP G 
Sbjct: 146  PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP 205

Query: 2799 ---------LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGA 2849
                        PG QG QG  G+ GEPG+ G  G  G PGPPG    PGD G  GK G 
Sbjct: 206  MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK---PGDDGEAGKPGK 262

Query: 2850 MGPRGPPGP------PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM 2903
             G RGPPGP      PG+PG PGV G  G PG  G  G  G  G+KGE G  G+  S   
Sbjct: 263  AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322

Query: 2904 MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR---NQPGPPGPPGP---------PG 2951
            M         + + G+  R        P     +R    QPGP GPPGP         PG
Sbjct: 323  MG-------PRGLPGERGRTG------PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 369

Query: 2952 SAGARGEPGPGGR---------PGFPGTPGMQGP------PGERGLPGEKGERGT-GSSG 2995
            + GA+GE GP G           G PGTPG  GP      PG  G+PG KG  G  G +G
Sbjct: 370  APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 429

Query: 2996 PRGLP---GPPGPQG-------ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              G P   GPPGPQG       + +TG PG  G +G  GP G PG +G +G PGP G
Sbjct: 430  APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAG 486



 Score =  242 bits (617), Expect = 5e-63
 Identities = 146/338 (43%), Positives = 167/338 (49%), Gaps = 53/338 (15%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802
            Q   G PGP GP G  G KG RG +G  GA G PG  G +GPPG  G PGP GP     P
Sbjct: 866  QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-----P 920

Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------- 2855
            G  G+ G KG  G+ G PGR G PGL GP GP G  G+ G  G  GA GP GP       
Sbjct: 921  GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 980

Query: 2856 -----PGPPGSPGSPGVTGPSGKPGK------PGDHGRPGPSGLKGEKGDRGDIASQNMM 2904
                 PG  G  G PG+ GPSG+PGK       GD G PGP G  G  G  G+   +   
Sbjct: 981  GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 1040

Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP------------GS 2952
             A           G   R      +       +   PG PGPPG P            G 
Sbjct: 1041 GA----------DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1090

Query: 2953 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG- 3007
            AGA+G  GP G  G  G  G QGP G++G  GE GERG     G +G +GLPGPPGP G 
Sbjct: 1091 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1150

Query: 3008 ESRTGPPGSTGSRGPP---GPPGRPGNSGIRGPPGPPG 3042
            +  +GP G +G RGPP   GP G+ G +GI GP GPPG
Sbjct: 1151 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188



 Score =  240 bits (612), Expect = 2e-62
 Identities = 148/353 (41%), Positives = 172/353 (48%), Gaps = 39/353 (11%)

Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 2799
            GPPGP GPAGGPG   A G +GE G +GA GP G +G  G PG  G PGP G +G     
Sbjct: 354  GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGKDGAMGPR 2853
             IPG +G  G  G AG PG PG  G PG  G  GP+GP      PG  GF G+ G  G  
Sbjct: 414  GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473

Query: 2854 GPPGPPGSP------------GSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGD- 2897
            GP GP G+P            G PG  GP G PG+   PG+ G PG  GL G KG  G+ 
Sbjct: 474  GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 533

Query: 2898 ----IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA 2953
                +A          +  E  + G      +  +  P         PG  G PGPPG  
Sbjct: 534  GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593

Query: 2954 GARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE- 3008
            GARG+PG  G PG  G  G  G  GE+GLPG  G RG     G +G  G PGP GP GE 
Sbjct: 594  GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653

Query: 3009 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
               G PG +G +G PGPPG PG  G  G  G PG   +      P   +G+PG
Sbjct: 654  GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG-PRGERGFPG 705



 Score =  240 bits (612), Expect = 2e-62
 Identities = 153/397 (38%), Positives = 178/397 (44%), Gaps = 94/397 (23%)

Query: 2747 GPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            G PG  G  G PGA G RG   + G +GA GPPGP G  G  G QG PGP G  GL  PG
Sbjct: 612  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--PG 669

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863
              G  G  G  G+ G+PG  G PGL GP G  G PG+RG  G  G  GPRG PG PG+ G
Sbjct: 670  PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729

Query: 2864 SPGVTGPSGKPGK---PGDHGRPGP---SGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917
              G +GP+G PG    PG  G PG    +G+ G KGDRGD+  +    A  +     L +
Sbjct: 730  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-T 788

Query: 2918 GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP 2977
            G +          P     +  + G  GPPGP GSAGARG PG  G  G PG  G  GPP
Sbjct: 789  GPIG---------PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839

Query: 2978 GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES--------------------- 3009
            G  G PG KGE+G        G+ GP+G  G PGPQG +                     
Sbjct: 840  GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899

Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGN---------------------------------- 3031
                R GPPGS G+ GPPGPPG  G                                   
Sbjct: 900  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959

Query: 3032 -----SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061
                 SG  GPPGP G         +P     +G+PG
Sbjct: 960  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996



 Score =  240 bits (612), Expect = 2e-62
 Identities = 135/301 (44%), Positives = 149/301 (49%), Gaps = 56/301 (18%)

Query: 2747 GPPGPPGPAGGPGAKG---PRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            GP GPPGPAG  G KG   P G  G +GA G PG RG+ GPPGP G  GP        PG
Sbjct: 789  GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------PG 840

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863
              G+ G KG+ GE G  G  G PG  GP G  GP G  G TG  GA G +GPPG  G PG
Sbjct: 841  ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900

Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923
            + G  GP G  G PG  G PGPSG  G KG RGD                          
Sbjct: 901  AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-------------------------- 934

Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983
                              GPPG  G PG  G  G PG  G PG  G  G +GPPG +GL 
Sbjct: 935  -----------------SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 977

Query: 2984 GEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041
            G++G  G  G  G RG PG PGP GE  + G PG++G RGPPGP G PG +G  G PG  
Sbjct: 978  GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 1037

Query: 3042 G 3042
            G
Sbjct: 1038 G 1038



 Score =  235 bits (599), Expect = 6e-61
 Identities = 143/336 (42%), Positives = 167/336 (49%), Gaps = 35/336 (10%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGP---------RGDIG 2783
            P  P   T      G  G PG AG  G +GP+GE G +G  G PGP         RG+ G
Sbjct: 439  PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498

Query: 2784 PPGPQGPPGPQG-PNGLSIPGEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGPMGPPG 2839
              GP GPPG +G P     PG+ G  G KG  GE    GL G  G  G PG PG  G PG
Sbjct: 499  GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558

Query: 2840 DRGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 2896
             RG TG+ G  GP+G  GP G+PG    PG  GP G  G+PG  G PGP G  GE G  G
Sbjct: 559  ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618

Query: 2897 D--IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PG 2948
            +  +     +R +  +  E   +G            P      R + G PGP      PG
Sbjct: 619  EKGLPGAPGLRGLPGKDGETGAAGPPG---------PAGPAGERGEQGAPGPSGFQGLPG 669

Query: 2949 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG 3007
            PPG  G  G+PG  G PG  G PG+ GP GERG PGE+G  G  G  GPRGLPG PG  G
Sbjct: 670  PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729

Query: 3008 -ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             +  +GP G  G++GPPG  G PG  G  G  GP G
Sbjct: 730  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765



 Score =  159 bits (402), Expect = 4e-38
 Identities = 97/238 (40%), Positives = 114/238 (47%), Gaps = 35/238 (14%)

Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            G PG PGP+G PG   A G  G+RG  G +GPPG  G  G PG +G PG  GP     PG
Sbjct: 993  GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PG 1047

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863
              G  G+KGD GE G  G  G PG PG PGP GP G +G  G+ GA GP GP GP G+ G
Sbjct: 1048 RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1107

Query: 2864 SPGVTGPSGKPGKPGDHGR------------------PGPSGLKGEKGDRGDIASQNMMR 2905
              G  GP G  G+ G+ G                   PGPSG +G  G  G    +    
Sbjct: 1108 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1167

Query: 2906 AVARQVCEQLISGQMNRFNQMLNQI-PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962
             V         SG+ +  N +   I P   +    + GP GPPG PG  G  G PGPG
Sbjct: 1168 PVGP-------SGK-DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1217



 Score =  112 bits (281), Expect = 4e-24
 Identities = 59/134 (44%), Positives = 67/134 (50%), Gaps = 17/134 (12%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P+ P      Q   GP G  G AG PG +G +G RG +G  G PGP G  G  G  GP G
Sbjct: 1099 PSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG 1158

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
            P GP                  G PG  G +G  G  G PGP+GPPG RG +G+ G  GP
Sbjct: 1159 PSGPR-----------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1201

Query: 2853 RGPPGPPGSPGSPG 2866
             G PGPPG PG PG
Sbjct: 1202 PGNPGPPGPPGPPG 1215



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 53/115 (46%), Positives = 56/115 (48%), Gaps = 22/115 (19%)

Query: 2740 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799
            T  Q   GPPGP G  G  G  GP G RG  G +GP G  G  G PGP GPPGP      
Sbjct: 1136 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP------ 1189

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPR 2853
                 +GR G  G AG P      G PG PGPPGP GP  D   F G    +GPR
Sbjct: 1190 -----RGRSGETGPAGPP------GNPGPPGPPGPPGPGIDMSAFAG----LGPR 1229


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  253 bits (647), Expect = 2e-66
 Identities = 148/337 (43%), Positives = 175/337 (51%), Gaps = 40/337 (11%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGER---GISGAIGPP------------- 2776
            P  P      +  VGPPGP G AG  GA G RGE    G +G  GPP             
Sbjct: 724  PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 783

Query: 2777 --GPRGDIGPPGPQGP---PGPQGPNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830
              G +GD G PGPQGP   PGPQGP G++ P G +G QG  G  G PG  GR G PG  G
Sbjct: 784  EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 843

Query: 2831 PPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890
             PGP GPPG    +GKDG  G RG  GPPG  G PG+ GP+G PG+ G+ G  GPSG +G
Sbjct: 844  NPGPPGPPGP---SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900

Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950
              G +G +A Q  +  +  Q  E+   G            P+     +  PG  G  GPP
Sbjct: 901  PPGPQG-LAGQRGIVGLPGQRGERGFPGLPG---------PSGEPGKQGAPGASGDRGPP 950

Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES 3009
            G  G  G  GP G PG  G+PG  GPPG  G  G KG+RG TG+ G  G PGPPG  G +
Sbjct: 951  GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1010

Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
                + G  G  G++GP GP G  G  GI+GP GP G
Sbjct: 1011 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047



 Score =  248 bits (634), Expect = 5e-65
 Identities = 146/335 (43%), Positives = 166/335 (49%), Gaps = 60/335 (17%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GPPGPPGP+G  G KG RG+ G  G  G PG +G  GPPG +G PG  GP+G    G  G
Sbjct: 846  GPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAE--GPPG 903

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866
             QG+ G  G  GLPG+ G  G PG PGP G PG +G     GA G RGPPGP G PG  G
Sbjct: 904  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQG---APGASGDRGPPGPVGPPGLTG 960

Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926
              G  G+ G PG  G PG  G  G KGDRG+  +     A                    
Sbjct: 961  PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA-------------------- 1000

Query: 2927 LNQIPNDYQSSRNQPGPPGPPGPPG---------SAGARGEPGPGGRPGFPGTPGMQGPP 2977
                          PGPPG PGP G          AGA+G  GP G  G  G  G QGP 
Sbjct: 1001 --------------PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1046

Query: 2978 GERGLPGEKGERGT----GSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPGNS 3032
            G++G  GE GERG     G +G +GLPGPPGP G+   +GP G +G RGPPGP G  G  
Sbjct: 1047 GDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKD 1106

Query: 3033 GIRG------PPGPPGYCDSSQCASIPYNGQGYPG 3061
            G  G      PPGP G    +  A  P N  G PG
Sbjct: 1107 GANGIPGPIGPPGPRGRSGETGPAGPPGN-PGPPG 1140



 Score =  248 bits (633), Expect = 7e-65
 Identities = 150/360 (41%), Positives = 177/360 (49%), Gaps = 70/360 (19%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP----------------- 2785
            Q  VGP G PG  G PG  GP+G RG  G +G PGP+G  G P                 
Sbjct: 503  QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562

Query: 2786 -------GPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEP---------GLPGRTGT 2825
                   G  GPPGP GP G       PG  G QG+ G  G P         G+PG  G 
Sbjct: 563  PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622

Query: 2826 PGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP---GKPGDHGR 2882
            PGL GP G  G PG+RG  G  G  GPRG PG PG+ G  G +GP+G P   G PG  G 
Sbjct: 623  PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682

Query: 2883 P---GPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939
            P   G +G+ G KGDRGD+  +    A  +     L +G +          P     +  
Sbjct: 683  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIG---------PPGPAGANG 732

Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TG 2992
            + G  GPPGP GSAGARG PG  G  G PG  G  GPPG  G PG KGE+G        G
Sbjct: 733  EKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792

Query: 2993 SSGPRGLPGPPGPQGESR-TGPPGSTGSRGPPGPP---------GRPGNSGIRGPPGPPG 3042
            + GP+G  G PGPQG +  TGP G+ G++GPPG           G PG++G  GPPGPPG
Sbjct: 793  APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852



 Score =  242 bits (617), Expect = 5e-63
 Identities = 146/338 (43%), Positives = 167/338 (49%), Gaps = 53/338 (15%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIP 2802
            Q   G PGP GP G  G KG RG +G  GA G PG  G +GPPG  G PGP GP     P
Sbjct: 797  QGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP-----P 851

Query: 2803 GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP------- 2855
            G  G+ G KG  G+ G PGR G PGL GP GP G  G+ G  G  GA GP GP       
Sbjct: 852  GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 911

Query: 2856 -----PGPPGSPGSPGVTGPSGKPGK------PGDHGRPGPSGLKGEKGDRGDIASQNMM 2904
                 PG  G  G PG+ GPSG+PGK       GD G PGP G  G  G  G+   +   
Sbjct: 912  GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 971

Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP------------GS 2952
             A           G   R      +       +   PG PGPPG P            G 
Sbjct: 972  GA----------DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGE 1021

Query: 2953 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQG- 3007
            AGA+G  GP G  G  G  G QGP G++G  GE GERG     G +G +GLPGPPGP G 
Sbjct: 1022 AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGD 1081

Query: 3008 ESRTGPPGSTGSRGPP---GPPGRPGNSGIRGPPGPPG 3042
            +  +GP G +G RGPP   GP G+ G +GI GP GPPG
Sbjct: 1082 QGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119



 Score =  240 bits (613), Expect = 1e-62
 Identities = 158/387 (40%), Positives = 180/387 (46%), Gaps = 100/387 (25%)

Query: 2743 QDSVGPPGPPGPAGGPGAKGPRGERGISGAIG------------------PPGPRGDIGP 2784
            +D VGP GPPGP G  G +GPRG+RG  G  G                  PPGP G  GP
Sbjct: 44   KDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP 103

Query: 2785 PG------------------------PQGPPGPQGPNGLSIP-GEQGRQGMKGDAGEPGL 2819
            PG                         QGP GP GP G   P G  G QG +G+ GEPG 
Sbjct: 104  PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGE 163

Query: 2820 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGP------PGSPGSPGVTGPSGK 2873
            PG +G  G  GPPGP G PGD G  GK G  G RGPPGP      PG+PG PGV G  G 
Sbjct: 164  PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 223

Query: 2874 PGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPND 2933
            PG  G  G  G  G+KGE G  G+  S   M         + + G+  R        P  
Sbjct: 224  PGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-------PRGLPGERGRTG------PAG 270

Query: 2934 YQSSR---NQPGPPGPPGP---------PGSAGARGEPGPGGR---------PGFPGTPG 2972
               +R    QPGP GPPGP         PG+ GA+GE GP G           G PGTPG
Sbjct: 271  AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330

Query: 2973 MQGP------PGERGLPGEKGERGT-GSSGPRGLP---GPPGPQG-------ESRTGPPG 3015
              GP      PG  G+PG KG  G  G +G  G P   GPPGPQG       + +TG PG
Sbjct: 331  SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390

Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              G +G  GP G PG +G +G PGP G
Sbjct: 391  IAGFKGEQGPKGEPGPAGPQGAPGPAG 417



 Score =  240 bits (612), Expect = 2e-62
 Identities = 148/353 (41%), Positives = 172/353 (48%), Gaps = 39/353 (11%)

Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL---- 2799
            GPPGP GPAGGPG   A G +GE G +GA GP G +G  G PG  G PGP G +G     
Sbjct: 285  GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGP------PGDRGFTGKDGAMGPR 2853
             IPG +G  G  G AG PG PG  G PG  G  GP+GP      PG  GF G+ G  G  
Sbjct: 345  GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404

Query: 2854 GPPGPPGSP------------GSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGD- 2897
            GP GP G+P            G PG  GP G PG+   PG+ G PG  GL G KG  G+ 
Sbjct: 405  GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 464

Query: 2898 ----IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA 2953
                +A          +  E  + G      +  +  P         PG  G PGPPG  
Sbjct: 465  GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 524

Query: 2954 GARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPRGLPGPPGPQGE- 3008
            GARG+PG  G PG  G  G  G  GE+GLPG  G RG     G +G  G PGP GP GE 
Sbjct: 525  GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584

Query: 3009 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
               G PG +G +G PGPPG PG  G  G  G PG   +      P   +G+PG
Sbjct: 585  GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG-PRGERGFPG 636



 Score =  240 bits (612), Expect = 2e-62
 Identities = 153/397 (38%), Positives = 178/397 (44%), Gaps = 94/397 (23%)

Query: 2747 GPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            G PG  G  G PGA G RG   + G +GA GPPGP G  G  G QG PGP G  GL  PG
Sbjct: 543  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--PG 600

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863
              G  G  G  G+ G+PG  G PGL GP G  G PG+RG  G  G  GPRG PG PG+ G
Sbjct: 601  PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660

Query: 2864 SPGVTGPSGKPGK---PGDHGRPGP---SGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917
              G +GP+G PG    PG  G PG    +G+ G KGDRGD+  +    A  +     L +
Sbjct: 661  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-T 719

Query: 2918 GQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPP 2977
            G +          P     +  + G  GPPGP GSAGARG PG  G  G PG  G  GPP
Sbjct: 720  GPIG---------PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770

Query: 2978 GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGES--------------------- 3009
            G  G PG KGE+G        G+ GP+G  G PGPQG +                     
Sbjct: 771  GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830

Query: 3010 ----RTGPPGSTGSRGPPGPPGRPGN---------------------------------- 3031
                R GPPGS G+ GPPGPPG  G                                   
Sbjct: 831  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890

Query: 3032 -----SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061
                 SG  GPPGP G         +P     +G+PG
Sbjct: 891  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927



 Score =  240 bits (612), Expect = 2e-62
 Identities = 135/301 (44%), Positives = 149/301 (49%), Gaps = 56/301 (18%)

Query: 2747 GPPGPPGPAGGPGAKG---PRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            GP GPPGPAG  G KG   P G  G +GA G PG RG+ GPPGP G  GP        PG
Sbjct: 720  GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP--------PG 771

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863
              G+ G KG+ GE G  G  G PG  GP G  GP G  G TG  GA G +GPPG  G PG
Sbjct: 772  ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831

Query: 2864 SPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRF 2923
            + G  GP G  G PG  G PGPSG  G KG RGD                          
Sbjct: 832  AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD-------------------------- 865

Query: 2924 NQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLP 2983
                              GPPG  G PG  G  G PG  G PG  G  G +GPPG +GL 
Sbjct: 866  -----------------SGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 908

Query: 2984 GEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041
            G++G  G  G  G RG PG PGP GE  + G PG++G RGPPGP G PG +G  G PG  
Sbjct: 909  GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 968

Query: 3042 G 3042
            G
Sbjct: 969  G 969



 Score =  235 bits (599), Expect = 6e-61
 Identities = 143/336 (42%), Positives = 167/336 (49%), Gaps = 35/336 (10%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGP---------RGDIG 2783
            P  P   T      G  G PG AG  G +GP+GE G +G  G PGP         RG+ G
Sbjct: 370  PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 429

Query: 2784 PPGPQGPPGPQG-PNGLSIPGEQGRQGMKGDAGE---PGLPGRTGTPGLPGPPGPMGPPG 2839
              GP GPPG +G P     PG+ G  G KG  GE    GL G  G  G PG PG  G PG
Sbjct: 430  GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489

Query: 2840 DRGFTGKDGAMGPRGPPGPPGSPGS---PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG 2896
             RG TG+ G  GP+G  GP G+PG    PG  GP G  G+PG  G PGP G  GE G  G
Sbjct: 490  ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 549

Query: 2897 D--IASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP------PG 2948
            +  +     +R +  +  E   +G            P      R + G PGP      PG
Sbjct: 550  EKGLPGAPGLRGLPGKDGETGAAGPPG---------PAGPAGERGEQGAPGPSGFQGLPG 600

Query: 2949 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG 3007
            PPG  G  G+PG  G PG  G PG+ GP GERG PGE+G  G  G  GPRGLPG PG  G
Sbjct: 601  PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660

Query: 3008 -ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             +  +GP G  G++GPPG  G PG  G  G  GP G
Sbjct: 661  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696



 Score =  234 bits (597), Expect = 1e-60
 Identities = 150/382 (39%), Positives = 172/382 (45%), Gaps = 104/382 (27%)

Query: 2746 VGPPGPPGPAGGPGAKGPRG---ERGISGAIGPPGPRGDIGPPGP--------------- 2787
            +GP GPPGPAG PG +G +G   E G  G  GP GPRG  GPPG                
Sbjct: 137  MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196

Query: 2788 QGPPGPQGPNGL----SIPGEQGRQ------GMKGDAGEPGLPGRTGTPGLPGPPGPMGP 2837
            +GPPGPQG  G      +PG +G +      G KG+AG PG+ G +G+PG  G PGPMGP
Sbjct: 197  RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256

Query: 2838 ---PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGD 2894
               PG+RG TG  GA G RG  G PG  G PG  GP+G PG PG  G  G +G  G +G 
Sbjct: 257  RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARG- 315

Query: 2895 RGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP----- 2949
                                                P   Q  R +PG PG PGP     
Sbjct: 316  ------------------------------------PEGAQGPRGEPGTPGSPGPAGASG 339

Query: 2950 -------PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-------TGSSG 2995
                   PG+ G+ G PG  G PGFPG  G  GP G  G  G KG+ G        G  G
Sbjct: 340  NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG 399

Query: 2996 PRGLPGPPGPQG-------ESRTGPPGSTGSRGPPGPPGR---------PGNSGIRGPPG 3039
            P+G PGP GPQG       E + G  G  G  GP GPPG          PG  G+ GP G
Sbjct: 400  PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKG 459

Query: 3040 PPGYCDSSQCASIPYNGQGYPG 3061
             PG    S  A  P    G PG
Sbjct: 460  APGERGPSGLAG-PKGANGDPG 480



 Score =  220 bits (560), Expect = 2e-56
 Identities = 145/340 (42%), Positives = 163/340 (47%), Gaps = 56/340 (16%)

Query: 2747 GPPGP------PGPAGGPGAKGPRGERGISGA---IGPPGPRGDIGPP------GPQGPP 2791
            GPPGP      PG  G PG KG RG  G+ GA    G PG +G+ G P      GP GP 
Sbjct: 198  GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 257

Query: 2792 GPQGPNGLSIP----GEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 2847
            G  G  G + P    G +G  G  G AG PG  G  G PG PG PG  G  G  G  G +
Sbjct: 258  GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317

Query: 2848 GAMGPRGPPGPPGSPGSPGVT---GPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 2904
            GA GPRG PG PGSPG  G +   G  G PG  G  G PG +G  G  G RG    Q   
Sbjct: 318  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377

Query: 2905 RAVA--RQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSA------GAR 2956
              +    Q  E  I+G                Q  + +PGP GP G PG A      GAR
Sbjct: 378  GPLGPKGQTGEPGIAGFKGE------------QGPKGEPGPAGPQGAPGPAGEEGKRGAR 425

Query: 2957 GEP---GPGGRPGFPGTPGMQGPPGERGLPGEK---GERG-TGSSGPRGLPGPPGPQGE- 3008
            GEP   GP G PG  G PG +G PG+ GL G K   GERG +G +GP+G  G PG  GE 
Sbjct: 426  GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485

Query: 3009 ------SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
                    TG PG  G +G  GP G PG  G  GPPGP G
Sbjct: 486  GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 525



 Score =  173 bits (438), Expect = 3e-42
 Identities = 118/309 (38%), Positives = 131/309 (42%), Gaps = 95/309 (30%)

Query: 2799 LSIPGEQGRQ-GMKGDAGEPG----LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPR 2853
            L   G+  RQ G KG  GEPG    + G  G PG  GP G  GP GDRG  G+ GA GPR
Sbjct: 21   LRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 80

Query: 2854 G------PPGPPGSPGSP---------------------------------GVTGPSGKP 2874
            G       PG PG PG P                                 G  GP G  
Sbjct: 81   GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140

Query: 2875 GKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY 2934
            G PG  G PGP G +G  G+ G                E  +SG M              
Sbjct: 141  GPPGPAGAPGPQGFQGNPGEPG----------------EPGVSGPM-------------- 170

Query: 2935 QSSRNQPGPPGPP------GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGE 2988
               R  PGPPG P      G PG AG RG PGP G  GFPGTPG+ G  G RG PG  G 
Sbjct: 171  -GPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA 229

Query: 2989 RG----------TGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGPPGPPGRPGNSGI 3034
            +G          +GS G  G PGP GP+G      RTGP G+ G+RG  G PG  G  G 
Sbjct: 230  KGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP 289

Query: 3035 RGPPGPPGY 3043
             GP G PG+
Sbjct: 290  VGPAGGPGF 298



 Score =  159 bits (402), Expect = 4e-38
 Identities = 97/238 (40%), Positives = 114/238 (47%), Gaps = 35/238 (14%)

Query: 2747 GPPGPPGPAGGPG---AKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPG 2803
            G PG PGP+G PG   A G  G+RG  G +GPPG  G  G PG +G PG  GP     PG
Sbjct: 924  GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PG 978

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPG 2863
              G  G+KGD GE G  G  G PG PG PGP GP G +G  G+ GA GP GP GP G+ G
Sbjct: 979  RDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARG 1038

Query: 2864 SPGVTGPSGKPGKPGDHGR------------------PGPSGLKGEKGDRGDIASQNMMR 2905
              G  GP G  G+ G+ G                   PGPSG +G  G  G    +    
Sbjct: 1039 IQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPG 1098

Query: 2906 AVARQVCEQLISGQMNRFNQMLNQI-PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPG 2962
             V         SG+ +  N +   I P   +    + GP GPPG PG  G  G PGPG
Sbjct: 1099 PVGP-------SGK-DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1148



 Score =  112 bits (281), Expect = 4e-24
 Identities = 59/134 (44%), Positives = 67/134 (50%), Gaps = 17/134 (12%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P+ P      Q   GP G  G AG PG +G +G RG +G  G PGP G  G  G  GP G
Sbjct: 1030 PSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAG 1089

Query: 2793 PQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGP 2852
            P GP                  G PG  G +G  G  G PGP+GPPG RG +G+ G  GP
Sbjct: 1090 PSGPR-----------------GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP 1132

Query: 2853 RGPPGPPGSPGSPG 2866
             G PGPPG PG PG
Sbjct: 1133 PGNPGPPGPPGPPG 1146



 Score =  111 bits (277), Expect = 1e-23
 Identities = 83/238 (34%), Positives = 91/238 (38%), Gaps = 94/238 (39%)

Query: 2879 DHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938
            D  +PGP G KGE GD  DI                                        
Sbjct: 27   DVRQPGPKGQKGEPGDIKDIVGPK------------------------------------ 50

Query: 2939 NQPGPPGPPGPPGSAGARGE---------PGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989
               GPPGP GP G  G RG+         PGP GR G PGTPG  GPPG  G PG  G  
Sbjct: 51   ---GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLG 107

Query: 2990 GT-------------------------GSSGPRGLPGP---PGPQG-ESRTGPPGS---- 3016
            G                          G  GPRG PGP   PGPQG +   G PG     
Sbjct: 108  GNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVS 167

Query: 3017 --TGSRGPPGPPGRPGN---------SGIRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061
               G RGPPGPPG+PG+         +G RGPPGP G         +P     +GYPG
Sbjct: 168  GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPG 225



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 53/115 (46%), Positives = 56/115 (48%), Gaps = 22/115 (19%)

Query: 2740 TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799
            T  Q   GPPGP G  G  G  GP G RG  G +GP G  G  G PGP GPPGP      
Sbjct: 1067 TGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP------ 1120

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPR 2853
                 +GR G  G AG P      G PG PGPPGP GP  D   F G    +GPR
Sbjct: 1121 -----RGRSGETGPAGPP------GNPGPPGPPGPPGPGIDMSAFAG----LGPR 1160


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  253 bits (647), Expect = 2e-66
 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 2792
            GPPGPPG  G  GA GP+G+RG  G  GPPG         P+GD+GP   PGP GPPG  
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 2793 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 2837
                  P GP G+      PG  G  G KGD G PGL     PG  G+PG+PG PGP+GP
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 2838 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885
            PG  G  GK GA            MGP GPPGP G PG  GV G  G  G  G  G PGP
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936

Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 2935
            +G KG KG+ G       +      +   L+  +  +    L  I     P  YQ     
Sbjct: 937  TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 2936 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 2976
                    QPG PGPPGP G+ G  G+PG    PG     G  GFPG  G++GP      
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 2977 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 3029
               PG  GLPG+KG++G       GLPG PGP+GE       G PG  GS G PG PG P
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 3030 GNSGIRGPPGPPGY 3043
            G  G +G PG PG+
Sbjct: 1110 GTPGAKGQPGLPGF 1123



 Score =  246 bits (629), Expect = 2e-64
 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%)

Query: 2746 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799
            +GPPGPPGP      +G PG KG  G +G  G  GP G +G  G PG  GPPGP  PN L
Sbjct: 901  MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 2800 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 2838
                         IPG  G +G +G  G+PG PG +G PGLPGPPGP G P         
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 2839 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 2887
                     GD GF G  G  GP GP G PG PGSPG+ G  G  G PG    G PG  G
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080

Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 2946
             KGE G  G   +  +  +V       L      +    L   P         PGPPGP 
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133

Query: 2947 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 2995
               GPPG+ G  GEPGP   GG PG PG PG +G PG+ G+P      GE G+ G G+ G
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193

Query: 2996 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            P GLPG  G +G+    G PG+ G  GP G PG  G  G++GPPGPPG
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241



 Score =  238 bits (608), Expect = 5e-62
 Identities = 148/329 (44%), Positives = 170/329 (51%), Gaps = 25/329 (7%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---PGAKGPRGERGISGAIGPPGPRGDIGPPGPQG 2789
            P  P   +    + G PG PGP GG   PG  GP GE+G  G  G PGP G  G PG  G
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 2790 --PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKD 2847
               PGP G  GLS  G++G  G+ G  G PGLPG  G PG  G PG  GPPG  G  G  
Sbjct: 1189 FGNPGPPGLPGLS--GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP- 1245

Query: 2848 GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
               GP+G PGP G PG PG TG  G PG  G  G PG  G+KGEKG+ G      +    
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1305

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRP 2965
              Q    L   Q N     LN +  D         PG  GP G PGSAG  GEPG  G P
Sbjct: 1306 GDQGPPGL---QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1362

Query: 2966 GFPGTPG-------MQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGE-SRTGPPGS 3016
            G PG PG       ++G  G  G+PG+ G +G  G  GP+GLPGP GP G+  R G PG 
Sbjct: 1363 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF 1422

Query: 3017 TGS---RGPPGPPGRPGNSGIRGPPGPPG 3042
             G+   +G PG PG+PG  G+ GPPGP G
Sbjct: 1423 DGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1451



 Score =  237 bits (604), Expect = 2e-61
 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 2800
            +G PGPPGP G PG  GP G  G  G IG  GP G  G PGP+G      PGP GP GL 
Sbjct: 706  IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764

Query: 2801 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 2843
             PG +G  G KGD    G PG PGRTG  GLPGP         PGPMGPPG  G      
Sbjct: 765  -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823

Query: 2844 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 2880
                         G  G  G +G PGPP           GSPG PG  GP G PG PG  
Sbjct: 824  PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883

Query: 2881 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938
            G+ G SG  G KG+ G +          +  +     + G      Q     P   + S+
Sbjct: 884  GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943

Query: 2939 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 2996
             +PG PGPPGP  P   G++GE    G PG PG PG+ GP G +GLPG+ G+   G SG 
Sbjct: 944  GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998

Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 3042
             GLPGPPGP+G    G PG  G  GPPG  G       PG  G+ GPPGP G
Sbjct: 999  PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048



 Score =  236 bits (601), Expect = 3e-61
 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%)

Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 2798
            D +  PGPPGP G PG KG +GE+G+ G  G         G  GPPG  G PG  GP G 
Sbjct: 448  DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 2857
            L  PG++G +G  G  G  GLPG  G PG PG PG  G PGD   F G  G  G  G PG
Sbjct: 508  LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567

Query: 2858 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917
             PG PG PG  G  G PG PG  G PG    KGE+G  G+     +   +          
Sbjct: 568  APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617

Query: 2918 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 2965
            G M    F           Q     PG PG PGP          PG  G  G PG  G  
Sbjct: 618  GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677

Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019
            G PG PG+ G PG  G+PG KGE G       G  GP+G PG PGP G    G PG  G 
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735

Query: 3020 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             GPPGPPG PG  G     + GPPGPPG     + A  P   +G+PG
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781



 Score =  234 bits (596), Expect = 1e-60
 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%)

Query: 2710 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 2769
            CSP   S+  C  I   + E   P         +   G PG PGP G PG   PRG++G 
Sbjct: 32   CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79

Query: 2770 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 2825
             G  GPPGP+G  GPPG  G PG  G  G+      PG QG  G  G  GE G PG  G 
Sbjct: 80   DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139

Query: 2826 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 2876
            PGL GPPGP G PG +G           G  G  G  GPPG  G PG  G+ GP G PG 
Sbjct: 140  PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199

Query: 2877 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 2935
            PG  G PGP GL G KG+ G +  Q        Q   Q   G   + ++    I  ++Q 
Sbjct: 200  PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257

Query: 2936 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 2973
                    R  PGPP   GPPGPP    G  G +GEPG    PG     G+PG PG PG 
Sbjct: 258  GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317

Query: 2974 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 3009
             G PGE G  GEKG++G TG  GP                    GLPG PG +GE     
Sbjct: 318  PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 3010 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 3042
              GPPG  G       GPPGPPG PG  G +G  GPPG
Sbjct: 378  IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415



 Score =  231 bits (588), Expect = 1e-59
 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GP G PG  G PG +G  G  GI G IGPPGP G +GPPGP G PGP+G  GL+  G +G
Sbjct: 168  GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227

Query: 2807 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 2849
             +G +G  G PG PG+              G  GLPG  GP GPPG RG  G    + G 
Sbjct: 228  EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287

Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 2909
             G +G PG  G PG  G  G  G PG PGD G PG  G  GEKG +GD         V  
Sbjct: 288  KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347

Query: 2910 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 2956
            +    +  G+       L  +P +         Q     PGPPG     PPGPPG  G R
Sbjct: 348  RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405

Query: 2957 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 3003
            G+ G  G PG   PG PG+ G PG  GLPG  G  G            G  GP G PG  
Sbjct: 406  GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465

Query: 3004 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 3046
            G QGE                   +GPPG  G  G PGPPG  G  G +G  G  G    
Sbjct: 466  GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525

Query: 3047 SQCASIP--YNGQGYPGS 3062
                 IP      G+PGS
Sbjct: 526  KGLPGIPGAPGAPGFPGS 543



 Score =  228 bits (582), Expect = 5e-59
 Identities = 144/342 (42%), Positives = 167/342 (48%), Gaps = 32/342 (9%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            S+G PG PGP G PG  G  G  GI G++G PG  G  G PG +G PG  G  G   PG 
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 2855
             G +G+ G  G PGLPG  G  G  G PG  GPPG++G  G+DG  GP G          
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 2856 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913
              PGPPG PG  G  G  G PG PG+ G PGP G  G  G  G         +    +  
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPAL-- 1247

Query: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 2973
            +   G            P  +Q     PGP GPPG PG+ G +GE G  G+PG PG PG+
Sbjct: 1248 EGPKGNPGPQGPPGRPGPTGFQ---GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1304

Query: 2974 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 3025
               QGPPG +G PG  G  G  G  G  G+PG PG +G S      GP G  G  GPPGP
Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364

Query: 3026 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 3061
            PG PG SG    I+G  GPPG         +  P   QG PG
Sbjct: 1365 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406



 Score =  223 bits (568), Expect = 2e-57
 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 2804
            G PG PGP G  G  G +GE+G +GA GP G  G  G PG  G PG +G  G  L+ PG 
Sbjct: 497  GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
                 MKGD GE G PG  G PGLPG PG  G PG  G  G+ G +  +G  GPPG+PG 
Sbjct: 556  -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 2918
            PG+ G  G  G PG  G PGP G KG +G  G+     +            Q  +  + G
Sbjct: 611  PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 2919 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 2965
               R   +   +P D              S+ +PG P  G PGPPG  G  G PGP G P
Sbjct: 670  NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 3007
            G PG  G++GPPG  G PG KGE G                   G  G RG PGPPGP G
Sbjct: 728  GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787

Query: 3008 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 3042
                +   GP G  G  G PGP G PG    G++GPPGPPG
Sbjct: 788  RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828



 Score =  219 bits (557), Expect = 4e-56
 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 2800
            G PG PGP G PG    +GERG  G  G PG  G+IGP GP G  PPGP G  G+     
Sbjct: 582  GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641

Query: 2801 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 2848
             PG+ G  G KGD G+          PG PGR G  GLPG PG  G PG  G  G  G  
Sbjct: 642  NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701

Query: 2849 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905
                +G  GPPGP G PG PG  G  G PG+ G  G PGP G  G KG+ G         
Sbjct: 702  GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753

Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 2956
            A+        + G    F   L       +  R  PGPPGPPG         P G  G  
Sbjct: 754  ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 2957 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 3015
            G+PGP G PG PG  G+QGPPG  G+PG  G+ G  G  G +G PGPPG         PG
Sbjct: 805  GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857

Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
              G RG PG PG PG  G  G PG PG   +S          G+PG+
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894



 Score =  218 bits (555), Expect = 7e-56
 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%)

Query: 2747 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 2792
            GPPGPPG  G PG     KG +GE+G  G  G PG  G+ G PG  G PG          
Sbjct: 267  GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 2793 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830
                       P GP GL IP           G  G  G+ G+ GE G PG  G PGLPG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 2831 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 2872
            PPG   MGPPG  GF G+ G  G  GPPG            PG+PG PG  GP+G     
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446

Query: 2873 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 2927
                 +PG PG  G PG  GL+GE+G +GD              C   I   ++      
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490

Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 2975
                         PG PG PG PG  G+ G P            GP G PG PG PG  G
Sbjct: 491  -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539

Query: 2976 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 3015
             PG +G P          G+KGE G+          G+ G  GLPG PGP+GE    P G
Sbjct: 540  FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595

Query: 3016 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 3043
             T  G RGPPG PG PG  G  GP GPPG+
Sbjct: 596  ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625



 Score =  209 bits (532), Expect = 3e-53
 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 2763
            P FP S     D +  PG  G  G                      PG  GP        
Sbjct: 538  PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 2764 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 2816
             +GERG  G  G PG  G+IGP GP   GPPGP G  G+      PG+ G  G KGD G+
Sbjct: 598  FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657

Query: 2817 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 2861
                      PG PGR G  GLPG PG  G PG  G  G  G      +G  GPPGP G 
Sbjct: 658  TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717

Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921
            PG PG  G  G PG+ G  G PGP G  G KG+ G         A+        + G   
Sbjct: 718  PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766

Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 2972
             F   L       +  R  PGPPGP         PGP G  G  G+PGP G PG PG  G
Sbjct: 767  -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819

Query: 2973 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 3025
            +QGPPG  G+PG  G+ G  G  G +G PGP     PGP GE    G PG+ G  GPPG 
Sbjct: 820  VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879

Query: 3026 PGRPGNS------------GIRGPPGPPG 3042
            PG PG +            G+ GPPGPPG
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908



 Score =  208 bits (530), Expect = 6e-53
 Identities = 125/300 (41%), Positives = 140/300 (46%), Gaps = 66/300 (22%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGP--------PGPQGPPGPQGPNG 2798
            G PG PG  G PG KG  G  G  G  GPPGP G  GP        PGPQGPPG  GP G
Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTG 1267

Query: 2799 LS-IPGEQGRQGMKGDAG---EPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854
               +PG +G  G+ G+ G   E G PG+ G PGLPG  G  GPPG +G  G+ G  G +G
Sbjct: 1268 FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1327

Query: 2855 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914
             PG PG PG PG+ GPSG PG  G  G PG  G  G  G  G      +++         
Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK--------- 1378

Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 2974
                                       G  GPPG PG  G +G PGP G  G PG  G  
Sbjct: 1379 ---------------------------GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPP 1411

Query: 2975 GPPGERGLPG------EKGERGT-GSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPG 3027
            G PG  GLPG       KG+ G  G  G RGL GPPGP            G +GPPGPPG
Sbjct: 1412 GDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD-----------GLQGPPGPPG 1460



 Score =  204 bits (520), Expect = 8e-52
 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%)

Query: 2745 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 2795
            ++GP GPPG  P G  G KG +G  G  G  G PGP+GD G        PG  G PG  G
Sbjct: 616  NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 2796 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 2833
              GL     +PG+ G  G+ G  GEPG+PG          G PG+PGPPG          
Sbjct: 676  DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 2834 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 2874
                       P         GPPG  G  G  GA+GP+G  G PG PG PG TG  G P
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 2875 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931
            G  GD   +G+PGP G  G  G    I  Q              I G + +    L+ IP
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842

Query: 2932 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989
             +    +  PGPPG   PGPPG  G+ G PG  G  G PG+PG+ G  G  G PG KGE 
Sbjct: 843  GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898

Query: 2990 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 3042
            G       G PGPPGP G   R+G PG  G  G  G PG PG +G +G       PGPPG
Sbjct: 899  GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 3043 YCDSSQCASIPYNGQ-GYPG 3061
              D +   S    G+ G PG
Sbjct: 954  PMDPNLLGSKGEKGEPGLPG 973



 Score =  139 bits (349), Expect = 6e-32
 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G PG PG  G PG KGP G   + G+ GP G  G IGPPGP G PGP G + + I G+ G
Sbjct: 1327 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1382

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866
              G+ G  G  GLPG  G  GLPGP GP G PG  G  G DGA G +G PG PG PG+ G
Sbjct: 1383 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1442

Query: 2867 VTGPSGKPGKPGDHGRPGPSGL 2888
            + GP G  G  G  G PG S +
Sbjct: 1443 LDGPPGPDGLQGPPGPPGTSSV 1464



 Score =  105 bits (263), Expect = 5e-22
 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%)

Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000
            PGP GPPGP G  G  G PGP G  G  G PG+ G PG  GLPG  G    G+ GP+G+P
Sbjct: 65   PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122

Query: 3001 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 3050
            G  G +GE    G PG  G +GPPGPPG PG  G         + GP G PGY       
Sbjct: 123  GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182

Query: 3051 SIPYNGQGYPG 3061
             +P    G PG
Sbjct: 183  GLP-GPTGIPG 192



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%)

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007
            G  G  G RG PG  G PG PG PG +GPPG RG  G+ G    G  GP+G+ GPPG  G
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99

Query: 3008 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043
               T    G PG  G+ GP G PG  G  G RG PG PG+
Sbjct: 100  FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139



 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%)

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 2997
            G P  A A     PG +    G  G +G  G  GL G  G  G     G  GPR      
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 2998 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 3057
            G+PGPPGP+G    GPPG  G  G PG PG PG+ G  GP G PG C+ ++        +
Sbjct: 81   GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131

Query: 3058 GYPGS 3062
            G+PGS
Sbjct: 132  GFPGS 136



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800
            GPPG PG  G PG  G  G +G  G  G PG RG  GPPGP   QGPPGP G + ++
Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  253 bits (647), Expect = 2e-66
 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 2792
            GPPGPPG  G  GA GP+G+RG  G  GPPG         P+GD+GP   PGP GPPG  
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 2793 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 2837
                  P GP G+      PG  G  G KGD G PGL     PG  G+PG+PG PGP+GP
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 2838 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885
            PG  G  GK GA            MGP GPPGP G PG  GV G  G  G  G  G PGP
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936

Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 2935
            +G KG KG+ G       +      +   L+  +  +    L  I     P  YQ     
Sbjct: 937  TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 2936 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 2976
                    QPG PGPPGP G+ G  G+PG    PG     G  GFPG  G++GP      
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 2977 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 3029
               PG  GLPG+KG++G       GLPG PGP+GE       G PG  GS G PG PG P
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 3030 GNSGIRGPPGPPGY 3043
            G  G +G PG PG+
Sbjct: 1110 GTPGAKGQPGLPGF 1123



 Score =  246 bits (629), Expect = 2e-64
 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%)

Query: 2746 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799
            +GPPGPPGP      +G PG KG  G +G  G  GP G +G  G PG  GPPGP  PN L
Sbjct: 901  MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 2800 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 2838
                         IPG  G +G +G  G+PG PG +G PGLPGPPGP G P         
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 2839 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 2887
                     GD GF G  G  GP GP G PG PGSPG+ G  G  G PG    G PG  G
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080

Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 2946
             KGE G  G   +  +  +V       L      +    L   P         PGPPGP 
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133

Query: 2947 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 2995
               GPPG+ G  GEPGP   GG PG PG PG +G PG+ G+P      GE G+ G G+ G
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193

Query: 2996 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            P GLPG  G +G+    G PG+ G  GP G PG  G  G++GPPGPPG
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241



 Score =  239 bits (611), Expect = 2e-62
 Identities = 156/372 (41%), Positives = 186/372 (50%), Gaps = 56/372 (15%)

Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 2782
            +P  + E   P +P +    + SVG PG PG  G PGAKG  G  G  G  GPPGP+G  
Sbjct: 1078 LPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 2783 GPPGPQGPPGPQGPNG-------LSIPGEQGRQGM---------KGDAGEPG-------- 2818
            GPPG  G PG  GP G          PGE+G+ G          KG+ G+PG        
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 2819 ---LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP--------GSPGV 2867
               L G+ G  GLPG PG  G PG +G  G  G  G +GPPGPPGSP        G+PG 
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 2868 TGPSGKPGKPGDH---GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924
             GP G+PG PG     G PG  G+KGEKG+ G      +      Q    L   Q N   
Sbjct: 1257 QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL---QGNPGR 1313

Query: 2925 QMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG-------MQG 2975
              LN +  D         PG  GP G PGSAG  GEPG  G PG PG PG       ++G
Sbjct: 1314 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1373

Query: 2976 PPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPP---GSTGSRGPPGPPGRPG 3030
              G  G+PG+ G +G  G  GP+GLPGP GP G+  R G P   G+ G +G PG PG+PG
Sbjct: 1374 DAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPG 1433

Query: 3031 NSGIRGPPGPPG 3042
              G+ GPPGP G
Sbjct: 1434 TRGLDGPPGPDG 1445



 Score =  237 bits (604), Expect = 2e-61
 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 2800
            +G PGPPGP G PG  GP G  G  G IG  GP G  G PGP+G      PGP GP GL 
Sbjct: 706  IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764

Query: 2801 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 2843
             PG +G  G KGD    G PG PGRTG  GLPGP         PGPMGPPG  G      
Sbjct: 765  -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823

Query: 2844 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 2880
                         G  G  G +G PGPP           GSPG PG  GP G PG PG  
Sbjct: 824  PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883

Query: 2881 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938
            G+ G SG  G KG+ G +          +  +     + G      Q     P   + S+
Sbjct: 884  GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943

Query: 2939 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 2996
             +PG PGPPGP  P   G++GE    G PG PG PG+ GP G +GLPG+ G+   G SG 
Sbjct: 944  GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998

Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 3042
             GLPGPPGP+G    G PG  G  GPPG  G       PG  G+ GPPGP G
Sbjct: 999  PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048



 Score =  236 bits (601), Expect = 3e-61
 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%)

Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 2798
            D +  PGPPGP G PG KG +GE+G+ G  G         G  GPPG  G PG  GP G 
Sbjct: 448  DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 2857
            L  PG++G +G  G  G  GLPG  G PG PG PG  G PGD   F G  G  G  G PG
Sbjct: 508  LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567

Query: 2858 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917
             PG PG PG  G  G PG PG  G PG    KGE+G  G+     +   +          
Sbjct: 568  APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617

Query: 2918 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 2965
            G M    F           Q     PG PG PGP          PG  G  G PG  G  
Sbjct: 618  GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677

Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019
            G PG PG+ G PG  G+PG KGE G       G  GP+G PG PGP G    G PG  G 
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735

Query: 3020 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             GPPGPPG PG  G     + GPPGPPG     + A  P   +G+PG
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781



 Score =  234 bits (596), Expect = 1e-60
 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%)

Query: 2710 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 2769
            CSP   S+  C  I   + E   P         +   G PG PGP G PG   PRG++G 
Sbjct: 32   CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79

Query: 2770 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 2825
             G  GPPGP+G  GPPG  G PG  G  G+      PG QG  G  G  GE G PG  G 
Sbjct: 80   DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139

Query: 2826 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 2876
            PGL GPPGP G PG +G           G  G  G  GPPG  G PG  G+ GP G PG 
Sbjct: 140  PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199

Query: 2877 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 2935
            PG  G PGP GL G KG+ G +  Q        Q   Q   G   + ++    I  ++Q 
Sbjct: 200  PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257

Query: 2936 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 2973
                    R  PGPP   GPPGPP    G  G +GEPG    PG     G+PG PG PG 
Sbjct: 258  GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317

Query: 2974 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 3009
             G PGE G  GEKG++G TG  GP                    GLPG PG +GE     
Sbjct: 318  PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 3010 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 3042
              GPPG  G       GPPGPPG PG  G +G  GPPG
Sbjct: 378  IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415



 Score =  231 bits (588), Expect = 1e-59
 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GP G PG  G PG +G  G  GI G IGPPGP G +GPPGP G PGP+G  GL+  G +G
Sbjct: 168  GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227

Query: 2807 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 2849
             +G +G  G PG PG+              G  GLPG  GP GPPG RG  G    + G 
Sbjct: 228  EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287

Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 2909
             G +G PG  G PG  G  G  G PG PGD G PG  G  GEKG +GD         V  
Sbjct: 288  KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347

Query: 2910 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 2956
            +    +  G+       L  +P +         Q     PGPPG     PPGPPG  G R
Sbjct: 348  RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405

Query: 2957 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 3003
            G+ G  G PG   PG PG+ G PG  GLPG  G  G            G  GP G PG  
Sbjct: 406  GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465

Query: 3004 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 3046
            G QGE                   +GPPG  G  G PGPPG  G  G +G  G  G    
Sbjct: 466  GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525

Query: 3047 SQCASIP--YNGQGYPGS 3062
                 IP      G+PGS
Sbjct: 526  KGLPGIPGAPGAPGFPGS 543



 Score =  230 bits (587), Expect = 1e-59
 Identities = 146/342 (42%), Positives = 166/342 (48%), Gaps = 38/342 (11%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            S+G PG PGP G PG  G  G  GI G++G PG  G  G PG +G PG  G  G   PG 
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 2855
             G +G+ G  G PGLPG  G  G  G PG  GPPG++G  G+DG  GP G          
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 2856 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913
              PGPPG PG  G  G  G PG PG+ G PGP   KGE G  G    Q            
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSP--G 1244

Query: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 2973
              + G         N  P         PGP GPPG PG+ G +GE G  G+PG PG PG+
Sbjct: 1245 PALEGPKG------NPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298

Query: 2974 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 3025
               QGPPG +G PG  G  G  G  G  G+PG PG +G S      GP G  G  GPPGP
Sbjct: 1299 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358

Query: 3026 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 3061
            PG PG SG    I+G  GPPG         +  P   QG PG
Sbjct: 1359 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1400



 Score =  223 bits (568), Expect = 2e-57
 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 2804
            G PG PGP G  G  G +GE+G +GA GP G  G  G PG  G PG +G  G  L+ PG 
Sbjct: 497  GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
                 MKGD GE G PG  G PGLPG PG  G PG  G  G+ G +  +G  GPPG+PG 
Sbjct: 556  -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 2918
            PG+ G  G  G PG  G PGP G KG +G  G+     +            Q  +  + G
Sbjct: 611  PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 2919 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 2965
               R   +   +P D              S+ +PG P  G PGPPG  G  G PGP G P
Sbjct: 670  NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 3007
            G PG  G++GPPG  G PG KGE G                   G  G RG PGPPGP G
Sbjct: 728  GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787

Query: 3008 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 3042
                +   GP G  G  G PGP G PG    G++GPPGPPG
Sbjct: 788  RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828



 Score =  219 bits (557), Expect = 4e-56
 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 2800
            G PG PGP G PG    +GERG  G  G PG  G+IGP GP G  PPGP G  G+     
Sbjct: 582  GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641

Query: 2801 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 2848
             PG+ G  G KGD G+          PG PGR G  GLPG PG  G PG  G  G  G  
Sbjct: 642  NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701

Query: 2849 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905
                +G  GPPGP G PG PG  G  G PG+ G  G PGP G  G KG+ G         
Sbjct: 702  GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753

Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 2956
            A+        + G    F   L       +  R  PGPPGPPG         P G  G  
Sbjct: 754  ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 2957 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 3015
            G+PGP G PG PG  G+QGPPG  G+PG  G+ G  G  G +G PGPPG         PG
Sbjct: 805  GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857

Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
              G RG PG PG PG  G  G PG PG   +S          G+PG+
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894



 Score =  218 bits (555), Expect = 7e-56
 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%)

Query: 2747 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 2792
            GPPGPPG  G PG     KG +GE+G  G  G PG  G+ G PG  G PG          
Sbjct: 267  GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 2793 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830
                       P GP GL IP           G  G  G+ G+ GE G PG  G PGLPG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 2831 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 2872
            PPG   MGPPG  GF G+ G  G  GPPG            PG+PG PG  GP+G     
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446

Query: 2873 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 2927
                 +PG PG  G PG  GL+GE+G +GD              C   I   ++      
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490

Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 2975
                         PG PG PG PG  G+ G P            GP G PG PG PG  G
Sbjct: 491  -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539

Query: 2976 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 3015
             PG +G P          G+KGE G+          G+ G  GLPG PGP+GE    P G
Sbjct: 540  FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595

Query: 3016 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 3043
             T  G RGPPG PG PG  G  GP GPPG+
Sbjct: 596  ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625



 Score =  215 bits (548), Expect = 5e-55
 Identities = 126/287 (43%), Positives = 140/287 (48%), Gaps = 46/287 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPP--GPQGPPGPQGPNGL-SIPG 2803
            G PG PG  G PG KG  G  G  G  GPPGP G  GP   GP+G PGPQGP G   +PG
Sbjct: 1208 GLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPG 1267

Query: 2804 EQGRQGMKGDAG---EPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPG 2860
             +G  G+ G+ G   E G PG+ G PGLPG  G  GPPG +G  G+ G  G +G PG PG
Sbjct: 1268 PEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPG 1327

Query: 2861 SPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQM 2920
             PG PG+ GPSG PG  G  G PG  G  G  G                           
Sbjct: 1328 VPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG--------------------------- 1360

Query: 2921 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 2980
                     +P     S    G  GPPG PG  G +G PGP G  G PG  G  G PG  
Sbjct: 1361 ---------LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN 1411

Query: 2981 GLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPG 3027
            GLPG  G    G  G  GLPG PG +G    GPPG  G +GPPGPPG
Sbjct: 1412 GLPGFDG--AGGRKGDPGLPGQPGTRG--LDGPPGPDGLQGPPGPPG 1454



 Score =  209 bits (532), Expect = 3e-53
 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 2763
            P FP S     D +  PG  G  G                      PG  GP        
Sbjct: 538  PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 2764 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 2816
             +GERG  G  G PG  G+IGP GP   GPPGP G  G+      PG+ G  G KGD G+
Sbjct: 598  FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657

Query: 2817 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 2861
                      PG PGR G  GLPG PG  G PG  G  G  G      +G  GPPGP G 
Sbjct: 658  TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717

Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921
            PG PG  G  G PG+ G  G PGP G  G KG+ G         A+        + G   
Sbjct: 718  PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766

Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 2972
             F   L       +  R  PGPPGP         PGP G  G  G+PGP G PG PG  G
Sbjct: 767  -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819

Query: 2973 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 3025
            +QGPPG  G+PG  G+ G  G  G +G PGP     PGP GE    G PG+ G  GPPG 
Sbjct: 820  VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879

Query: 3026 PGRPGNS------------GIRGPPGPPG 3042
            PG PG +            G+ GPPGPPG
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908



 Score =  204 bits (520), Expect = 8e-52
 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%)

Query: 2745 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 2795
            ++GP GPPG  P G  G KG +G  G  G  G PGP+GD G        PG  G PG  G
Sbjct: 616  NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 2796 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 2833
              GL     +PG+ G  G+ G  GEPG+PG          G PG+PGPPG          
Sbjct: 676  DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 2834 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 2874
                       P         GPPG  G  G  GA+GP+G  G PG PG PG TG  G P
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 2875 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931
            G  GD   +G+PGP G  G  G    I  Q              I G + +    L+ IP
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842

Query: 2932 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989
             +    +  PGPPG   PGPPG  G+ G PG  G  G PG+PG+ G  G  G PG KGE 
Sbjct: 843  GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898

Query: 2990 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 3042
            G       G PGPPGP G   R+G PG  G  G  G PG PG +G +G       PGPPG
Sbjct: 899  GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 3043 YCDSSQCASIPYNGQ-GYPG 3061
              D +   S    G+ G PG
Sbjct: 954  PMDPNLLGSKGEKGEPGLPG 973



 Score =  139 bits (349), Expect = 6e-32
 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G PG PG  G PG KGP G   + G+ GP G  G IGPPGP G PGP G + + I G+ G
Sbjct: 1321 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1376

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866
              G+ G  G  GLPG  G  GLPGP GP G PG  G  G DGA G +G PG PG PG+ G
Sbjct: 1377 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1436

Query: 2867 VTGPSGKPGKPGDHGRPGPSGL 2888
            + GP G  G  G  G PG S +
Sbjct: 1437 LDGPPGPDGLQGPPGPPGTSSV 1458



 Score =  105 bits (263), Expect = 5e-22
 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%)

Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000
            PGP GPPGP G  G  G PGP G  G  G PG+ G PG  GLPG  G    G+ GP+G+P
Sbjct: 65   PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122

Query: 3001 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 3050
            G  G +GE    G PG  G +GPPGPPG PG  G         + GP G PGY       
Sbjct: 123  GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182

Query: 3051 SIPYNGQGYPG 3061
             +P    G PG
Sbjct: 183  GLP-GPTGIPG 192



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%)

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007
            G  G  G RG PG  G PG PG PG +GPPG RG  G+ G    G  GP+G+ GPPG  G
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99

Query: 3008 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043
               T    G PG  G+ GP G PG  G  G RG PG PG+
Sbjct: 100  FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139



 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%)

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 2997
            G P  A A     PG +    G  G +G  G  GL G  G  G     G  GPR      
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 2998 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 3057
            G+PGPPGP+G    GPPG  G  G PG PG PG+ G  GP G PG C+ ++        +
Sbjct: 81   GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131

Query: 3058 GYPGS 3062
            G+PGS
Sbjct: 132  GFPGS 136



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800
            GPPG PG  G PG  G  G +G  G  G PG RG  GPPGP   QGPPGP G + ++
Sbjct: 1403 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 31/64 (48%), Positives = 32/64 (50%), Gaps = 6/64 (9%)

Query: 2743 QDSVGPPGPPGPAGGPGAK------GPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGP 2796
            Q   G PGP GP G PG        G  G +G  G  G PG RG  GPPGP G  GP GP
Sbjct: 1393 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP 1452

Query: 2797 NGLS 2800
             G S
Sbjct: 1453 PGTS 1456


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  253 bits (647), Expect = 2e-66
 Identities = 159/374 (42%), Positives = 184/374 (49%), Gaps = 84/374 (22%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---------PRGDIGP---PGPQGPPG-- 2792
            GPPGPPG  G  GA GP+G+RG  G  GPPG         P+GD+GP   PGP GPPG  
Sbjct: 757  GPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLP 816

Query: 2793 ------PQGPNGL----SIPGEQGRQGMKGDAGEPGL-----PGRTGTPGLPGPPGPMGP 2837
                  P GP G+      PG  G  G KGD G PGL     PG  G+PG+PG PGP+GP
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 2838 PGDRGFTGKDGA------------MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP 2885
            PG  G  GK GA            MGP GPPGP G PG  GV G  G  G  G  G PGP
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936

Query: 2886 SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQI-----PNDYQ----- 2935
            +G KG KG+ G       +      +   L+  +  +    L  I     P  YQ     
Sbjct: 937  TGEKGSKGEPG-------LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD 989

Query: 2936 ----SSRNQPGPPGPPGPPGSAGARGEPG----PG-----GRPGFPGTPGMQGP------ 2976
                    QPG PGPPGP G+ G  G+PG    PG     G  GFPG  G++GP      
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 2977 ---PGERGLPGEKGERGTGSSGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRP 3029
               PG  GLPG+KG++G       GLPG PGP+GE       G PG  GS G PG PG P
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109

Query: 3030 GNSGIRGPPGPPGY 3043
            G  G +G PG PG+
Sbjct: 1110 GTPGAKGQPGLPGF 1123



 Score =  246 bits (629), Expect = 2e-64
 Identities = 150/348 (43%), Positives = 174/348 (50%), Gaps = 58/348 (16%)

Query: 2746 VGPPGPPGP------AGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL 2799
            +GPPGPPGP      +G PG KG  G +G  G  GP G +G  G PG  GPPGP  PN L
Sbjct: 901  MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 2800 ------------SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPP--------- 2838
                         IPG  G +G +G  G+PG PG +G PGLPGPPGP G P         
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 2839 ---------GDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPG--DHGRPGPSG 2887
                     GD GF G  G  GP GP G PG PGSPG+ G  G  G PG    G PG  G
Sbjct: 1021 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1080

Query: 2888 LKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGP- 2946
             KGE G  G   +  +  +V       L      +    L   P         PGPPGP 
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP-------GTPGPPGPK 1133

Query: 2947 --PGPPGSAGARGEPGP---GGRPGFPGTPGMQGPPGERGLP------GEKGERGTGSSG 2995
               GPPG+ G  GEPGP   GG PG PG PG +G PG+ G+P      GE G+ G G+ G
Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193

Query: 2996 PRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            P GLPG  G +G+    G PG+ G  GP G PG  G  G++GPPGPPG
Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241



 Score =  238 bits (606), Expect = 9e-62
 Identities = 156/375 (41%), Positives = 185/375 (49%), Gaps = 59/375 (15%)

Query: 2723 IPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDI 2782
            +P  + E   P +P +    + SVG PG PG  G PGAKG  G  G  G  GPPGP+G  
Sbjct: 1078 LPGPKGEPGLPGYPGN-PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 2783 GPPGPQGPPGPQGPNG-------LSIPGEQGRQGM---------KGDAGEPG-------- 2818
            GPPG  G PG  GP G          PGE+G+ G          KG+ G+PG        
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 2819 ---LPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSP-----GSPGVTGP 2870
               L G+ G  GLPG PG  G PG +G  G  G  G +GPPGPPGSP     G  G  GP
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 2871 SGKPGKPGDHGRPGP---------SGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921
             G PG+PG  G PGP          G+KGEKG+ G      +      Q    L   Q N
Sbjct: 1257 QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL---QGN 1313

Query: 2922 RFNQMLNQIPND--YQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPG------- 2972
                 LN +  D         PG  GP G PGSAG  GEPG  G PG PG PG       
Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1373

Query: 2973 MQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGE-SRTGPP---GSTGSRGPPGPPG 3027
            ++G  G  G+PG+ G +G  G  GP+GLPGP GP G+  R G P   G+ G +G PG PG
Sbjct: 1374 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1433

Query: 3028 RPGNSGIRGPPGPPG 3042
            +PG  G+ GPPGP G
Sbjct: 1434 QPGTRGLDGPPGPDG 1448



 Score =  237 bits (604), Expect = 2e-61
 Identities = 151/352 (42%), Positives = 172/352 (48%), Gaps = 64/352 (18%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGP-----PGPQGPNGLS 2800
            +G PGPPGP G PG  GP G  G  G IG  GP G  G PGP+G      PGP GP GL 
Sbjct: 706  IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL- 764

Query: 2801 IPGEQGRQGMKGD---AGEPGLPGRTGTPGLPGP---------PGPMGPPGDRGF----- 2843
             PG +G  G KGD    G PG PGRTG  GLPGP         PGPMGPPG  G      
Sbjct: 765  -PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823

Query: 2844 ------------TGKDGAMGPRGPPGPP-----------GSPGSPGVTGPSGKPGKPGDH 2880
                         G  G  G +G PGPP           GSPG PG  GP G PG PG  
Sbjct: 824  PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP 883

Query: 2881 GRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSR 2938
            G+ G SG  G KG+ G +          +  +     + G      Q     P   + S+
Sbjct: 884  GKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943

Query: 2939 NQPGPPGPPGP--PGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGP 2996
             +PG PGPPGP  P   G++GE    G PG PG PG+ GP G +GLPG+ G+   G SG 
Sbjct: 944  GEPGLPGPPGPMDPNLLGSKGEK---GEPGLPGIPGVSGPKGYQGLPGDPGQ--PGLSGQ 998

Query: 2997 RGLPGPPGPQGESRTGPPGSTGSRGPPGPPGR------PGNSGIRGPPGPPG 3042
             GLPGPPGP+G    G PG  G  GPPG  G       PG  G+ GPPGP G
Sbjct: 999  PGLPGPPGPKG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSG 1048



 Score =  236 bits (601), Expect = 3e-61
 Identities = 146/347 (42%), Positives = 164/347 (47%), Gaps = 42/347 (12%)

Query: 2744 DSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPG----PRGDIGPPGPQGPPGPQGPNG- 2798
            D +  PGPPGP G PG KG +GE+G+ G  G         G  GPPG  G PG  GP G 
Sbjct: 448  DEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGS 507

Query: 2799 LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD-RGFTGKDGAMGPRGPPG 2857
            L  PG++G +G  G  G  GLPG  G PG PG PG  G PGD   F G  G  G  G PG
Sbjct: 508  LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567

Query: 2858 PPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLIS 2917
             PG PG PG  G  G PG PG  G PG    KGE+G  G+     +   +          
Sbjct: 568  APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNI---------- 617

Query: 2918 GQMN--RFNQMLNQIPNDYQSSRNQPGPPGPPGP----------PGSAGARGEPGPGGRP 2965
            G M    F           Q     PG PG PGP          PG  G  G PG  G  
Sbjct: 618  GPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV 677

Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------TGSSGPRGLPGPPGPQGESRTGPPGSTGS 3019
            G PG PG+ G PG  G+PG KGE G       G  GP+G PG PGP G    G PG  G 
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPG--APGTPGRIGL 735

Query: 3020 RGPPGPPGRPGNSG-----IRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             GPPGPPG PG  G     + GPPGPPG     + A  P   +G+PG
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPG-LPGFKGALGPKGDRGFPG 781



 Score =  234 bits (596), Expect = 1e-60
 Identities = 163/398 (40%), Positives = 185/398 (46%), Gaps = 79/398 (19%)

Query: 2710 CSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGI 2769
            CSP   S+  C  I   + E   P         +   G PG PGP G PG   PRG++G 
Sbjct: 32   CSP--GSKCDCSGIKGEKGERGFPGL-------EGHPGLPGFPGPEGPPG---PRGQKGD 79

Query: 2770 SGAIGPPGPRGDIGPPGPQGPPGPQGPNGL----SIPGEQGRQGMKGDAGEPGLPGRTGT 2825
             G  GPPGP+G  GPPG  G PG  G  G+      PG QG  G  G  GE G PG  G 
Sbjct: 80   DGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139

Query: 2826 PGLPGPPGPMGPPGDRG---------FTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGK 2876
            PGL GPPGP G PG +G           G  G  G  GPPG  G PG  G+ GP G PG 
Sbjct: 140  PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199

Query: 2877 PGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQ- 2935
            PG  G PGP GL G KG+ G +  Q        Q   Q   G   + ++    I  ++Q 
Sbjct: 200  PGLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL-QGPPGPPGQISEQKRPIDVEFQK 257

Query: 2936 ------SSRNQPGPP---GPPGPP----GSAGARGEPG----PG-----GRPGFPGTPGM 2973
                    R  PGPP   GPPGPP    G  G +GEPG    PG     G+PG PG PG 
Sbjct: 258  GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317

Query: 2974 QGPPGERGLPGEKGERG-TGSSGPR-------------------GLPGPPGPQGE----S 3009
             G PGE G  GEKG++G TG  GP                    GLPG PG +GE     
Sbjct: 318  PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 3010 RTGPPGSTGS-----RGPPGPPGRPGNSGIRGPPGPPG 3042
              GPPG  G       GPPGPPG PG  G +G  GPPG
Sbjct: 378  IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG 415



 Score =  231 bits (588), Expect = 1e-59
 Identities = 149/378 (39%), Positives = 170/378 (44%), Gaps = 64/378 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GP G PG  G PG +G  G  GI G IGPPGP G +GPPGP G PGP+G  GL+  G +G
Sbjct: 168  GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKG 227

Query: 2807 RQGMKGDAGEPGLPGRT-------------GTPGLPGPPGPMGPPGDRGFTG----KDGA 2849
             +G +G  G PG PG+              G  GLPG  GP GPPG RG  G    + G 
Sbjct: 228  EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGE 287

Query: 2850 MGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVAR 2909
             G +G PG  G PG  G  G  G PG PGD G PG  G  GEKG +GD         V  
Sbjct: 288  KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347

Query: 2910 QVCEQLISGQMNRFNQMLNQIPND--------YQSSRNQPGPPG-----PPGPPGSAGAR 2956
            +    +  G+       L  +P +         Q     PGPPG     PPGPPG  G R
Sbjct: 348  RPGTGITIGEKGNIG--LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER 405

Query: 2957 GEPGPGGRPGF--PGTPGMQGPPGERGLPGEKGERGT-----------GSSGPRGLPGPP 3003
            G+ G  G PG   PG PG+ G PG  GLPG  G  G            G  GP G PG  
Sbjct: 406  GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDK 465

Query: 3004 GPQGESR-----------------TGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDS 3046
            G QGE                   +GPPG  G  G PGPPG  G  G +G  G  G    
Sbjct: 466  GLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGP 525

Query: 3047 SQCASIP--YNGQGYPGS 3062
                 IP      G+PGS
Sbjct: 526  KGLPGIPGAPGAPGFPGS 543



 Score =  230 bits (586), Expect = 2e-59
 Identities = 146/342 (42%), Positives = 167/342 (48%), Gaps = 35/342 (10%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            S+G PG PGP G PG  G  G  GI G++G PG  G  G PG +G PG  G  G   PG 
Sbjct: 1072 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG--TPGP 1129

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGP--------- 2855
             G +G+ G  G PGLPG  G  G  G PG  GPPG++G  G+DG  GP G          
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 2856 --PGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCE 2913
              PGPPG PG  G  G  G PG PG+ G PGP   KGE G  G    Q            
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP---KGEPGFHGFPGVQGPPGPPGSP--G 1244

Query: 2914 QLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGM 2973
              + G          Q P      +  PGP GPPG PG+ G +GE G  G+PG PG PG+
Sbjct: 1245 PALEGPKGNPGP---QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1301

Query: 2974 ---QGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGES----RTGPPGSTGSRGPPGP 3025
               QGPPG +G PG  G  G  G  G  G+PG PG +G S      GP G  G  GPPGP
Sbjct: 1302 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1361

Query: 3026 PGRPGNSG----IRGPPGPPGYCDSSQCASI--PYNGQGYPG 3061
            PG PG SG    I+G  GPPG         +  P   QG PG
Sbjct: 1362 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1403



 Score =  223 bits (568), Expect = 2e-57
 Identities = 142/341 (41%), Positives = 166/341 (48%), Gaps = 54/341 (15%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG--LSIPGE 2804
            G PG PGP G  G  G +GE+G +GA GP G  G  G PG  G PG +G  G  L+ PG 
Sbjct: 497  GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG- 555

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
                 MKGD GE G PG  G PGLPG PG  G PG  G  G+ G +  +G  GPPG+PG 
Sbjct: 556  -----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM------MRAVARQVCEQLISG 2918
            PG+ G  G  G PG  G PGP G KG +G  G+     +            Q  +  + G
Sbjct: 611  PGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 2919 QMNRFNQMLNQIPND-----------YQSSRNQPGPP--GPPGPPGSAGARGEPGPGGRP 2965
               R   +   +P D              S+ +PG P  G PGPPG  G  G PGP G P
Sbjct: 670  NPGRDGDV--GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAP 727

Query: 2966 GFPGTPGMQGPPGERGLPGEKGERG------------------TGSSGPRGLPGPPGPQG 3007
            G PG  G++GPPG  G PG KGE G                   G  G RG PGPPGP G
Sbjct: 728  GTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG 787

Query: 3008 ----ESRTGPPGSTGSRGPPGPPGRPG--NSGIRGPPGPPG 3042
                +   GP G  G  G PGP G PG    G++GPPGPPG
Sbjct: 788  RTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828



 Score =  219 bits (557), Expect = 4e-56
 Identities = 146/347 (42%), Positives = 165/347 (47%), Gaps = 65/347 (18%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQG--PPGPQGPNGLS---- 2800
            G PG PGP G PG    +GERG  G  G PG  G+IGP GP G  PPGP G  G+     
Sbjct: 582  GLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAG 641

Query: 2801 IPGEQGRQGMKGDAGE----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-- 2848
             PG+ G  G KGD G+          PG PGR G  GLPG PG  G PG  G  G  G  
Sbjct: 642  NPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEP 701

Query: 2849 ---AMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR 2905
                +G  GPPGP G PG PG  G  G PG+ G  G PGP G  G KG+ G         
Sbjct: 702  GIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-------- 753

Query: 2906 AVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---------PPGSAGAR 2956
            A+        + G    F   L       +  R  PGPPGPPG         P G  G  
Sbjct: 754  ALPGPPGPPGLPG----FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 2957 GEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQGESRTGPPG 3015
            G+PGP G PG PG  G+QGPPG  G+PG  G+ G  G  G +G PGPPG         PG
Sbjct: 805  GQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG------LDVPG 857

Query: 3016 STGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
              G RG PG PG PG  G  G PG PG   +S          G+PG+
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS----------GFPGT 894



 Score =  218 bits (555), Expect = 7e-56
 Identities = 151/390 (38%), Positives = 172/390 (44%), Gaps = 124/390 (31%)

Query: 2747 GPPGPPGPAGGPGA----KGPRGERGISGAIGPPGPRGDIGPPGPQGPPG---------- 2792
            GPPGPPG  G PG     KG +GE+G  G  G PG  G+ G PG  G PG          
Sbjct: 267  GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 2793 -----------PQGPNGLSIP-----------GEQGRQGMKGDAGEPGLPGRTGTPGLPG 2830
                       P GP GL IP           G  G  G+ G+ GE G PG  G PGLPG
Sbjct: 327  DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 2831 PPGP--MGPPGDRGFTGKDGAMGPRGPPG-----------PPGSPGSPGVTGPSG----- 2872
            PPG   MGPPG  GF G+ G  G  GPPG            PG+PG PG  GP+G     
Sbjct: 387  PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPP 446

Query: 2873 -----KPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQML 2927
                 +PG PG  G PG  GL+GE+G +GD              C   I   ++      
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGD----------TCFNCIGTGIS------ 490

Query: 2928 NQIPNDYQSSRNQPGPPGPPGPPGSAGARGEP------------GPGGRPGFPGTPGMQG 2975
                         PG PG PG PG  G+ G P            GP G PG PG PG  G
Sbjct: 491  -----------GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPG 539

Query: 2976 PPGERGLP----------GEKGERGT----------GSSGPRGLPGPPGPQGESRTGPPG 3015
             PG +G P          G+KGE G+          G+ G  GLPG PGP+GE    P G
Sbjct: 540  FPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE----PGG 595

Query: 3016 ST--GSRGPPGPPGRPGNSGIRGPPGPPGY 3043
             T  G RGPPG PG PG  G  GP GPPG+
Sbjct: 596  ITFKGERGPPGNPGLPGLPGNIGPMGPPGF 625



 Score =  211 bits (536), Expect = 1e-53
 Identities = 129/312 (41%), Positives = 144/312 (46%), Gaps = 67/312 (21%)

Query: 2743 QDSVGPPGP---------------PGPAGGPGAKGPRGE---RGISGAIGPPGPRGDIGP 2784
            Q   G PGP               PG  G PG  GP+GE    G  G  GPPGP G  GP
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 2785 --PGPQGPPGPQGPNG----LSIPGEQGRQGMKGDA---GEPGLPGRTGTPGLPGPPGPM 2835
               GP+G PGPQGP G      +PG +G  G+ G+    GE G PG+ G PGLPG  G  
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305

Query: 2836 GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDR 2895
            GPPG +G  G+ G  G +G PG PG PG PG+ GPSG PG  G  G PG  G  G  G  
Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG-- 1363

Query: 2896 GDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGA 2955
                                              +P     S    G  GPPG PG  G 
Sbjct: 1364 ----------------------------------LPGPSGQSIIIKGDAGPPGIPGQPGL 1389

Query: 2956 RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPG 3015
            +G PGP G  G PG  G  G PG  GLPG  G    G  G  GLPG PG +G    GPPG
Sbjct: 1390 KGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG--AGGRKGDPGLPGQPGTRG--LDGPPG 1445

Query: 3016 STGSRGPPGPPG 3027
              G +GPPGPPG
Sbjct: 1446 PDGLQGPPGPPG 1457



 Score =  209 bits (532), Expect = 3e-53
 Identities = 152/389 (39%), Positives = 172/389 (44%), Gaps = 97/389 (24%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG---------------------PGAKGP-------- 2763
            P FP S     D +  PG  G  G                      PG  GP        
Sbjct: 538  PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 597

Query: 2764 -RGERGISGAIGPPGPRGDIGPPGPQ--GPPGPQGPNGL----SIPGEQGRQGMKGDAGE 2816
             +GERG  G  G PG  G+IGP GP   GPPGP G  G+      PG+ G  G KGD G+
Sbjct: 598  FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657

Query: 2817 ----------PGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDG-----AMGPRGPPGPPGS 2861
                      PG PGR G  GLPG PG  G PG  G  G  G      +G  GPPGP G 
Sbjct: 658  TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717

Query: 2862 PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMN 2921
            PG PG  G  G PG+ G  G PGP G  G KG+ G         A+        + G   
Sbjct: 718  PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG--------FALPGPPGPPGLPG--- 766

Query: 2922 RFNQMLNQIPNDYQSSRNQPGPPGP---------PGPPGSAGARGEPGPGGRPGFPGTPG 2972
             F   L       +  R  PGPPGP         PGP G  G  G+PGP G PG PG  G
Sbjct: 767  -FKGALGP-----KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-G 819

Query: 2973 MQGPPGERGLPGEKGERGT-GSSGPRGLPGP-----PGPQGE-SRTGPPGSTGSRGPPGP 3025
            +QGPPG  G+PG  G+ G  G  G +G PGP     PGP GE    G PG+ G  GPPG 
Sbjct: 820  VQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGS 879

Query: 3026 PGRPGNS------------GIRGPPGPPG 3042
            PG PG +            G+ GPPGPPG
Sbjct: 880  PGLPGKAGASGFPGTKGEMGMMGPPGPPG 908



 Score =  204 bits (520), Expect = 8e-52
 Identities = 149/380 (39%), Positives = 175/380 (46%), Gaps = 85/380 (22%)

Query: 2745 SVGPPGPPG--PAGGPGAKGPRGERGISGAIGPPGPRGDIGP-------PGPQGPPGPQG 2795
            ++GP GPPG  P G  G KG +G  G  G  G PGP+GD G        PG  G PG  G
Sbjct: 616  NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 2796 PNGL----SIPGEQGRQGMKGDAGEPGLPG--------RTGTPGLPGPPG---------- 2833
              GL     +PG+ G  G+ G  GEPG+PG          G PG+PGPPG          
Sbjct: 676  DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 2834 -----------PM--------GPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKP 2874
                       P         GPPG  G  G  GA+GP+G  G PG PG PG TG  G P
Sbjct: 736  EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 2875 GKPGD---HGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931
            G  GD   +G+PGP G  G  G    I  Q              I G + +    L+ IP
Sbjct: 796  GPKGDVGPNGQPGPMGPPGLPG----IGVQGPPGPPG-------IPGPIGQ--PGLHGIP 842

Query: 2932 NDYQSSRNQPGPPG--PPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGER 2989
             +    +  PGPPG   PGPPG  G+ G PG  G  G PG+PG+ G  G  G PG KGE 
Sbjct: 843  GE----KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEM 898

Query: 2990 GTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGP------PGPPG 3042
            G       G PGPPGP G   R+G PG  G  G  G PG PG +G +G       PGPPG
Sbjct: 899  GM-----MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 3043 YCDSSQCASIPYNGQ-GYPG 3061
              D +   S    G+ G PG
Sbjct: 954  PMDPNLLGSKGEKGEPGLPG 973



 Score =  139 bits (349), Expect = 6e-32
 Identities = 72/142 (50%), Positives = 82/142 (57%), Gaps = 4/142 (2%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G PG PG  G PG KGP G   + G+ GP G  G IGPPGP G PGP G + + I G+ G
Sbjct: 1324 GDPGLPGVPGFPGMKGPSG---VPGSAGPEGEPGLIGPPGPPGLPGPSGQS-IIIKGDAG 1379

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866
              G+ G  G  GLPG  G  GLPGP GP G PG  G  G DGA G +G PG PG PG+ G
Sbjct: 1380 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1439

Query: 2867 VTGPSGKPGKPGDHGRPGPSGL 2888
            + GP G  G  G  G PG S +
Sbjct: 1440 LDGPPGPDGLQGPPGPPGTSSV 1461



 Score =  105 bits (263), Expect = 5e-22
 Identities = 60/131 (45%), Positives = 68/131 (51%), Gaps = 13/131 (9%)

Query: 2941 PGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLP 3000
            PGP GPPGP G  G  G PGP G  G  G PG+ G PG  GLPG  G    G+ GP+G+P
Sbjct: 65   PGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH--DGAPGPQGIP 122

Query: 3001 GPPGPQGESR-TGPPGSTGSRGPPGPPGRPGNSG---------IRGPPGPPGYCDSSQCA 3050
            G  G +GE    G PG  G +GPPGPPG PG  G         + GP G PGY       
Sbjct: 123  GCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQ 182

Query: 3051 SIPYNGQGYPG 3061
             +P    G PG
Sbjct: 183  GLP-GPTGIPG 192



 Score = 90.9 bits (224), Expect = 2e-17
 Identities = 49/100 (49%), Positives = 55/100 (55%), Gaps = 6/100 (6%)

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG 3007
            G  G  G RG PG  G PG PG PG +GPPG RG  G+ G    G  GP+G+ GPPG  G
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGI--PGPPGPKGIRGPPGLPG 99

Query: 3008 ESRT----GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043
               T    G PG  G+ GP G PG  G  G RG PG PG+
Sbjct: 100  FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF 139



 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 50/125 (40%), Positives = 60/125 (48%), Gaps = 19/125 (15%)

Query: 2948 GPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG----TGSSGPR------ 2997
            G P  A A     PG +    G  G +G  G  GL G  G  G     G  GPR      
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 2998 GLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQ 3057
            G+PGPPGP+G    GPPG  G  G PG PG PG+ G  GP G PG C+ ++        +
Sbjct: 81   GIPGPPGPKG--IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG-CNGTK------GER 131

Query: 3058 GYPGS 3062
            G+PGS
Sbjct: 132  GFPGS 136



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 30/57 (52%), Positives = 34/57 (59%), Gaps = 3/57 (5%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGP---QGPPGPQGPNGLS 2800
            GPPG PG  G PG  G  G +G  G  G PG RG  GPPGP   QGPPGP G + ++
Sbjct: 1406 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
            sapiens]
          Length = 678

 Score =  253 bits (647), Expect = 2e-66
 Identities = 148/353 (41%), Positives = 177/353 (50%), Gaps = 45/353 (12%)

Query: 2742 TQDSVGPPGPPGPAGG---------PGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            T+   G PGPPG AG          PGAKG  GE+G +GA G PG  G+ G PG QGPPG
Sbjct: 311  TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 370

Query: 2793 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMG--------------- 2836
              GP G   +PG +G  G  G  G PG  G  G+PGLPG PGP G               
Sbjct: 371  EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 430

Query: 2837 PPGDRGFTGKDGAMGPRGP------PGPPGS---PGSPGVTGPSGKPGKPGDHGRPGPSG 2887
            P G++G +G++G  G RG       PGP GS   PG PG+ GP G  G PG  G  GP G
Sbjct: 431  PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490

Query: 2888 LKGEKGDRGDIASQNMMRAVAR--------QVCEQLISGQMNRFNQMLNQIPNDYQSSRN 2939
             +G +G++G      +     R        QVC ++I          L +  +       
Sbjct: 491  PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550

Query: 2940 QPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGL 2999
            +PGPPGPPGPPG  G  G+ G  G PG  G PG  G  G +G  GEKGERG    GP GL
Sbjct: 551  RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGL 610

Query: 3000 PGP---PGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQC 3049
            PG    PG  G +  G  G  G RGPPG  G PG  G  GPPG PG+C+ + C
Sbjct: 611  PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 663



 Score =  241 bits (614), Expect = 1e-62
 Identities = 139/328 (42%), Positives = 170/328 (51%), Gaps = 38/328 (11%)

Query: 2739 CTCTQDSVGPPGPPGPAGGPGA---KGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQG 2795
            C   +   G  GPPGP G PG     G  G+RG  G  GPPGP G+ G PG  G PG  G
Sbjct: 21   CAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 80

Query: 2796 PNGLSIP-GEQGRQGMKGDAGEPGLPGRTGTP--GLPGPPGPMGP---PGDRGFTGKDGA 2849
             +GL+ P G  G  G KG  GEPG+PG  G P  G+PGPPGP G    PG+ G  G  G 
Sbjct: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGD 140

Query: 2850 MGPRGPPGPPGSPGSPGVTG--------PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQ 2901
             G RGPPGPPG PG  G  G        P+  P  PG  G PG  G++G KG +G+I   
Sbjct: 141  PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP--PGRSGYPGLPGMRGHKGAKGEIGEP 198

Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961
                    +       G      ++  Q P   Q  R   G  G  G  G+ G  GEPGP
Sbjct: 199  GRQGHKGEE-------GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251

Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGES-------RTGPP 3014
             G PG PG  G +GPPGE G  G++     G+ G RG+PG PGP+G++       R G P
Sbjct: 252  QGLPGAPGDQGQRGPPGEAGPKGDR-----GAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306

Query: 3015 GSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G  G++G PG PG PG++G++G PG PG
Sbjct: 307  GMPGTKGEPGKPGPPGDAGLQGLPGVPG 334



 Score =  232 bits (591), Expect = 5e-60
 Identities = 149/358 (41%), Positives = 174/358 (48%), Gaps = 41/358 (11%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            P  PN+C   +   G PG PG  G  GAKG  GE G  G  G  G +G++G  G QGPPG
Sbjct: 166  PLCPNACPPGRS--GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 223

Query: 2793 PQGPNGLS----IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGK-- 2846
             QG  G++      GE+G +G+ G+ G  GLPG  G  G  GPPG  GP GDRG  G   
Sbjct: 224  AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 283

Query: 2847 -DGAMGPRGPPGPPGS------PGSPGVTGPSGKPGKPGDHGR---------PGPSGLKG 2890
              G  GP+G  G PG       PG PG  G  GKPG PGD G          PG  G+ G
Sbjct: 284  IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG 343

Query: 2891 EKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPP 2950
            EKG  G       M    +        GQ     ++  + P     SR + GP G PG P
Sbjct: 344  EKGSTGAPGKPGQMGNSGKP-------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 396

Query: 2951 GSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT----GSSGPRGLPGP---P 3003
            G  G+ G PG  G PG PG PGM+G  G  G PG KGE+G     G +G RG  G    P
Sbjct: 397  GKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 456

Query: 3004 GPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
            GP+G +  G PG  G RGP G  G PG  G RGPPGP G         +P   QG PG
Sbjct: 457  GPKGSA--GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP-GVQGPPG 511



 Score =  212 bits (539), Expect = 5e-54
 Identities = 148/393 (37%), Positives = 168/393 (42%), Gaps = 101/393 (25%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG---PRGDIG------------------PP 2785
            G PG  G  G PG  GP+G+RG  GA G PG   P+GD G                   P
Sbjct: 256  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315

Query: 2786 GPQGPPGPQGPNGL-SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFT 2844
            G  GPPG  G  GL  +PG  G +G+ G+ G  G PG+ G  G  G PG  GPPG+ G  
Sbjct: 316  GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375

Query: 2845 GKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMM 2904
            G  G  G RG  GP GSPG PG  G  G PG PG    PGP GL G KGDRG +      
Sbjct: 376  GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPK 432

Query: 2905 RAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPG---P 2961
                    EQ  SG+     +            R + G  G PGP GSAG  GEPG   P
Sbjct: 433  G-------EQGASGEEGEAGE------------RGELGDIGLPGPKGSAGNPGEPGLRGP 473

Query: 2962 GGRPGFPGTPGMQGPPGERGLPGEKGERG------------------------------- 2990
             G  G PG  G +GPPG RG+ GE+G  G                               
Sbjct: 474  EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533

Query: 2991 ------------TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGP- 3037
                        TG  G  G PGPPGP GE+  G PG  G RG PG  G PG  G+RGP 
Sbjct: 534  MAASLKRPDSGATGLPGRPGPPGPPGPPGEN--GFPGQMGIRGLPGIKGPPGALGLRGPK 591

Query: 3038 --------PGPPGYCDSSQCASIPYNGQGYPGS 3062
                     GPPG   +    +I   G   P S
Sbjct: 592  GDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 624



 Score =  107 bits (268), Expect = 1e-22
 Identities = 79/245 (32%), Positives = 90/245 (36%), Gaps = 95/245 (38%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGL------ 2799
            VG PGP G  G  G +G  GERG  G IG PGP+G  G PG  G  GP+G  GL      
Sbjct: 426  VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 485

Query: 2800 -------SIPGEQGRQGMKGDAGEPGLP------------------------------GR 2822
                    + GEQG  G+ G  G PG                                G 
Sbjct: 486  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545

Query: 2823 TGTPGLPGPPGPMGPPGDRGFTGK------------DGAMGPRGPPG---------PPGS 2861
            TG PG PGPPGP GPPG+ GF G+             GA+G RGP G         PPG 
Sbjct: 546  TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 605

Query: 2862 -------------------------------PGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890
                                           PG  G+ G  G PG PG  G   P+    
Sbjct: 606  GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 665

Query: 2891 EKGDR 2895
            + G R
Sbjct: 666  QAGQR 670



 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 51/121 (42%), Positives = 60/121 (49%), Gaps = 25/121 (20%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPG------PRGDIGPPGPQGPPGPQGPNGL- 2799
            GPPGPPGP G  G  G  G RG+ G  GPPG      P+GD+G  G +GPPG +GPNGL 
Sbjct: 553  GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 611

Query: 2800 ---SIPGEQG-----RQGMKGDAGEPGL---------PGRTGTPGLPGPPGPMGPPGDRG 2842
                +PG+ G     R G  G+ G PG+         PG  G PG   P       G R 
Sbjct: 612  GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 671

Query: 2843 F 2843
            F
Sbjct: 672  F 672


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  252 bits (644), Expect = 3e-66
 Identities = 152/361 (42%), Positives = 173/361 (47%), Gaps = 34/361 (9%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPG 2792
            PA P          G PGPPGPAG  G  G  G+ G  G  G  G +GD GPPGP GP G
Sbjct: 789  PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848

Query: 2793 PQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMG 2851
            P GP G +  PG +G +G  G  G  G PG  G  G PGP G  GPPG  G  GK+G  G
Sbjct: 849  PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908

Query: 2852 PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQV 2911
            PRG  GP G PG  G  GP G  G+ G  G  GP+G  G  G +G IA Q  +  +  Q 
Sbjct: 909  PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG-IAGQRGVVGLPGQR 967

Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG---PPGSAGARGEPGPGGRPGFP 2968
             E+   G      +   Q P+     R  PGP GPPG   PPG +G  G PG  G PG  
Sbjct: 968  GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD 1027

Query: 2969 GTPGMQG---------PPGERGLPGEKGERG-TGSSGPRGLPGPPGPQGESRTGPPGSTG 3018
            G+PG +G         PPG  G PG  G  G  G SG RG  GP GP G    GP G+ G
Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP--VGPVGARG 1085

Query: 3019 SRGPPGPPGRPGN---------------SGIRGPPGPPGYC--DSSQCASIPYNGQGYPG 3061
              GP GP G  G                SG++GPPGPPG         AS P   +G PG
Sbjct: 1086 PAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPG 1145

Query: 3062 S 3062
            S
Sbjct: 1146 S 1146



 Score =  250 bits (638), Expect = 2e-65
 Identities = 151/361 (41%), Positives = 177/361 (49%), Gaps = 59/361 (16%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G PGPPG  GGPG++G  G  G++G  GP G RG  GP GP+G PG  G      PGE G
Sbjct: 479  GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR-----PGEAG 533

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGP------PGPMGPPGDRGFTGKDGAMGPRGPPGPPG 2860
              G KG  G PG PG  G  G PGP      PGP GPPG RG  G  G  GP+G  G PG
Sbjct: 534  LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593

Query: 2861 S------PGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMR--------A 2906
                   PG PG  GP+GK G+ G  G PGP+G  GE+G++G   S              
Sbjct: 594  KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653

Query: 2907 VARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP------PGSAGARGEPG 2960
             A +  EQ + G +        +    +   R   GPPGP GP      PG+ GA+G+ G
Sbjct: 654  EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713

Query: 2961 PGGRPGFPGTPGMQGPPGERG---LPGEKGERGT----------GSSGPRGLPGPPGPQG 3007
              G PG  G PG+QG PGERG   LPG KG+RG           G  G RGL GP GP G
Sbjct: 714  APGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773

Query: 3008 ESRTGPPGSTGSRGPPGPPG------RPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPG 3061
             +  G PG  G  GP GP G       PG+ G  GPPGP G+         P    G PG
Sbjct: 774  PA--GAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG-------PPGADGQPG 824

Query: 3062 S 3062
            +
Sbjct: 825  A 825



 Score =  248 bits (634), Expect = 5e-65
 Identities = 142/314 (45%), Positives = 159/314 (50%), Gaps = 36/314 (11%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGE 2804
            + GPPGPPGPAG  G KGPRGE G +G  G  GP G  GP G +G PG  GP G   PG 
Sbjct: 891  NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGA--PGT 948

Query: 2805 QGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGS 2864
             G QG+ G  G  GLPG+ G  G PG PGP G PG +   G  GA G RGPPGP G PG 
Sbjct: 949  PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ---GPSGASGERGPPGPMGPPGL 1005

Query: 2865 PGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFN 2924
             G  G SG+ G PG  G PG  G  G KGDRG+        A         +        
Sbjct: 1006 AGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG------- 1058

Query: 2925 QMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGR---------------PGFPG 2969
                  P      R + GP GP GP G  GARG  GP G                 G  G
Sbjct: 1059 ------PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRG 1112

Query: 2970 TPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGR 3028
              G+QGPPG  G PGE+G   +G+SGP G  GPPG  G   + G  G  G  GPPGP GR
Sbjct: 1113 FSGLQGPPGPPGSPGEQGP--SGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170

Query: 3029 PGNSGIRGPPGPPG 3042
             G++G  GPPGPPG
Sbjct: 1171 TGDAGPVGPPGPPG 1184



 Score =  248 bits (633), Expect = 7e-65
 Identities = 147/351 (41%), Positives = 170/351 (48%), Gaps = 41/351 (11%)

Query: 2724 PSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIG 2783
            P+ +D    P  P         +G PGP G AG PG  G RG  G  GA+GP G  G+ G
Sbjct: 558  PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAG 617

Query: 2784 PPGPQGPPGPQGPNG----LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPG 2839
              GP GP GP G  G       PG QG  G  G  GE G PG  G PG  G PGP G  G
Sbjct: 618  AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARG 677

Query: 2840 DRGFTGKDGAMGPRGPPGP---PGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE----- 2891
            +RGF G+ G  GP GP GP    G+PG+ G  G +G PG PG  G PG  G+ GE     
Sbjct: 678  ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737

Query: 2892 ----KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPP 2947
                KGDRGD   +    +  +        G       +    P      + + GP GP 
Sbjct: 738  LPGPKGDRGDAGPKGADGSPGK-------DGVRGLTGPIGPPGPAGAPGDKGESGPSGPA 790

Query: 2948 GPPGSAGA---RGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG-TGSSGPRGLPGPP 3003
            GP G+ GA   RGEPGP G  GF G PG  G PG +G PG+ G +G  G  GP G  GPP
Sbjct: 791  GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPP 850

Query: 3004 GPQGESRTGPPGSTGSRGPPGPPGR------------PGNSGIRGPPGPPG 3042
            GP G    G PG+ G+RG  GPPG             PG SG  GPPGPPG
Sbjct: 851  GPIG--NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG 899



 Score =  248 bits (632), Expect = 9e-65
 Identities = 157/387 (40%), Positives = 173/387 (44%), Gaps = 95/387 (24%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGG------------PGAKGPRGERGISGAIGPPGPRG 2780
            P  P      Q   G PGPPGPAG             PGAKG  G  GI+GA G PG RG
Sbjct: 357  PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416

Query: 2781 DIGPPGPQGPPGPQGPNG-------------LSIPGEQGRQGMKGDAGEPGLPGRTGTPG 2827
              GP GP GPPGP+G +G                PG  G QG  G AGE G  G  G PG
Sbjct: 417  PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG 476

Query: 2828 ---LPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPG 2884
               LPGPPG  G PG RGF G DG  GP+GP G  GSPG  G  G  G+ G+PG+ G PG
Sbjct: 477  PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPG 536

Query: 2885 PSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPP 2944
              GL G  G  G                                  P        +PGPP
Sbjct: 537  AKGLTGSPGSPGPDGKTG----------------------------PPGPAGQDGRPGPP 568

Query: 2945 GPPGP---------PGSAGARGEPGPGGRPGFPGTP------------GMQGPPGERGLP 2983
            GPPG          PG  GA GEPG  G  G PG P            G QGPPG  G  
Sbjct: 569  GPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628

Query: 2984 GEKGERG-TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGR------PGNSGIR 3035
            GE+GE+G  GS G +GLPGP GP GE+ + G  G  G  G PGP G       PG  G++
Sbjct: 629  GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688

Query: 3036 GPPGPPGYCDSSQCASIPYNGQGYPGS 3062
            GPPGP G          P    G PG+
Sbjct: 689  GPPGPAG----------PRGANGAPGN 705



 Score =  243 bits (620), Expect = 2e-63
 Identities = 135/297 (45%), Positives = 151/297 (50%), Gaps = 51/297 (17%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GP GPPGPAG PG KG       SG  GP GP G  G PG +G PGP GP G +  G  G
Sbjct: 767  GPIGPPGPAGAPGDKGE------SGPSGPAGPTGARGAPGDRGEPGPPGPAGFA--GPPG 818

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPG 2866
              G  G  GEPG  G  G  G PGP GP GPPG  G  G  GA G RG  GPPG+ G PG
Sbjct: 819  ADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPG 878

Query: 2867 VTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM 2926
              G  G PG  G+ G PGP G  G++G +G                              
Sbjct: 879  AAGRVGPPGPSGNAGPPGPPGPAGKEGGKG------------------------------ 908

Query: 2927 LNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEK 2986
                P        +PG  GPPGPPG AG +G PG  G  G PGTPG QG  G+RG+ G  
Sbjct: 909  ----PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964

Query: 2987 GERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G+R     G RG PG PGP GE  + GP G++G RGPPGP G P   G+ GPPG  G
Sbjct: 965  GQR-----GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP---GLAGPPGESG 1013



 Score =  239 bits (609), Expect = 4e-62
 Identities = 142/331 (42%), Positives = 164/331 (49%), Gaps = 46/331 (13%)

Query: 2747 GPPGPPGPAG----------------------GPGAKGPRGERGISGAIGPPGPRGDIGP 2784
            GPPGPPGP G                       PG  GP G RG+ G  G PGP+G  GP
Sbjct: 145  GPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGP 204

Query: 2785 PGPQGPPGPQGPNG-LSIPGEQGRQGMKGDAGEPGLPGRTGTPG------LPGPPGPMGP 2837
            PG  G PG  GP G    PG  G+ G  G+AG+PG PG  G PG      LPG  G  G 
Sbjct: 205  PGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGM 264

Query: 2838 PGDRGFTGKDGAMG---PRGPPGPPGSP---GSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891
             G RGF+G DGA G   P GP G PGSP   G+PG  GP G PG+ G  G PGP+G +G 
Sbjct: 265  KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324

Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPG 2951
             G  G                     G +    +   Q P   +  +   G PGPPGP G
Sbjct: 325  DGATGAAGPPGPTGPAG----PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG 380

Query: 2952 SAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRT 3011
            +AG  G PG  G+   PG  G  G PG  G PG  G R  G SGP+G  GPPGP+G S  
Sbjct: 381  AAGPAGNPGADGQ---PGAKGANGAPGIAGAPGFPGAR--GPSGPQGPGGPPGPKGNS-- 433

Query: 3012 GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
            G PG+ GS+G  G  G PG  G++GPPGP G
Sbjct: 434  GEPGAPGSKGDTGAKGEPGPVGVQGPPGPAG 464



 Score =  238 bits (607), Expect = 7e-62
 Identities = 141/319 (44%), Positives = 161/319 (50%), Gaps = 64/319 (20%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS---- 2800
            + GPPGP GPAG PG  G  G +G +G   P GPRG  GP G +G PGP GP G +    
Sbjct: 330  AAGPPGPTGPAGPPGFPGAVGAKGEAG---PQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386

Query: 2801 IPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM---GPPGDRGFTGKDGAMGPRGPPG 2857
             PG  G+ G KG  G PG+ G  G PG  GP GP    GPPG +G +G+ GA G +G  G
Sbjct: 387  NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG 446

Query: 2858 PPGSPGSPGV---TGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914
              G PG  GV    GP+G+ GK G  G PGP+GL G  G+RG                  
Sbjct: 447  AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG----------------- 489

Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQ 2974
                                  SR  PG  G  GP G AG RG PGP G     G+PG  
Sbjct: 490  --------------------PGSRGFPGADGVAGPKGPAGERGSPGPAGP---KGSPGEA 526

Query: 2975 GPPGERGLPGEKGERGT-GSSGPRGLPGPPGPQG-ESRTGPPGSTGSR---------GPP 3023
            G PGE GLPG KG  G+ GS GP G  GPPGP G + R GPPG  G+R         GP 
Sbjct: 527  GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPK 586

Query: 3024 GPPGRPGNSGIRGPPGPPG 3042
            G  G PG +G RG PGPPG
Sbjct: 587  GAAGEPGKAGERGVPGPPG 605



 Score =  225 bits (573), Expect = 6e-58
 Identities = 136/333 (40%), Positives = 154/333 (46%), Gaps = 55/333 (16%)

Query: 2724 PSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAG------------GPGAKGPRGERGISG 2771
            P+ ++ GK P            VGPPGPPGPAG             PG  GP+G  G  G
Sbjct: 900  PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959

Query: 2772 AIGPPGPRGDIG---PPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGL 2828
             +G PG RG+ G    PGP G PG QGP+G S  GE+G  G  G  G  G PG +G  G 
Sbjct: 960  VVGLPGQRGERGFPGLPGPSGEPGKQGPSGAS--GERGPPGPMGPPGLAGPPGESGREGA 1017

Query: 2829 PGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGL 2888
            PG  G  G  G  G  G  G  GP GPPG PG+PG+PG  GP+GK G  G+ G  GP+G 
Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077

Query: 2889 KGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPG 2948
             G  G RG    Q                             P   +    + G  G  G
Sbjct: 1078 VGPVGARGPAGPQG----------------------------PRGDKGETGEQGDRGIKG 1109

Query: 2949 PPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGE 3008
              G +G +G PGP G PG  G  G  GP G RG PG  G    G  G  GLPGP GP   
Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG--APGKDGLNGLPGPIGP--- 1164

Query: 3009 SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041
               GP G TG  GP GPPG PG     GPPGPP
Sbjct: 1165 --PGPRGRTGDAGPVGPPGPPGPP---GPPGPP 1192



 Score =  140 bits (352), Expect = 3e-32
 Identities = 101/274 (36%), Positives = 117/274 (42%), Gaps = 44/274 (16%)

Query: 2826 PGLPGPPG---PMGPPGDRGFTGKD--GAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH 2880
            PG   P G   P+ P G    T ++  G  GP+G  GP G  G  G  G  G PG+PG  
Sbjct: 82   PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 2881 GRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQM------LNQIPNDY 2934
            G PGP G  G  G  G+ A Q       +      + G M                P  +
Sbjct: 142  GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201

Query: 2935 QSSRNQPGPP---------GPPGPPGSAGARGEPGPGGRPGFPGTPGMQGP---PGERGL 2982
            Q    +PG P         GPPGPPG  G  GE G  GRPG  G PG QG    PG  GL
Sbjct: 202  QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261

Query: 2983 PGEKGERG----------TGSSGPRGLPGPPGPQG-ESRTGP---PGSTGSRGPPGPPGR 3028
            PG KG RG           G +GP+G PG PG  G   + GP   PG  G  G PGP G 
Sbjct: 262  PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321

Query: 3029 PGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
             GN G  G  GPPG        + P    G+PG+
Sbjct: 322  RGNDGATGAAGPPG-------PTGPAGPPGFPGA 348



 Score = 73.2 bits (178), Expect = 4e-12
 Identities = 34/60 (56%), Positives = 35/60 (58%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            GP GP GP G  GA G  G  G+ G IGPPGPRG  G  GP GPPGP GP G   P   G
Sbjct: 1136 GPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  252 bits (643), Expect = 5e-66
 Identities = 150/347 (43%), Positives = 169/347 (48%), Gaps = 66/347 (19%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG----LS 2800
            + GPPGPPG AG PG +G  GERG  G+ GP G +G+ G PG  G PG  GP G    + 
Sbjct: 709  AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 2801 IPGEQGRQGMKGDAGEPGLPGRTGTPGLP------GPPGPMGPPGDRGFTGKDGAMGPRG 2854
             PG  G+ G KG+ G PGLPG  G  G P      GPPGP G PG  G  G+ G  G RG
Sbjct: 769  PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828

Query: 2855 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQ 2914
             PG  G  G PGV GP   PG  G  G PGP G+KGE+G  G   +              
Sbjct: 829  APGEKGEGGPPGVAGP---PGGSGPAGPPGPQGVKGERGSPGGPGAAG------------ 873

Query: 2915 LISGQMNRFNQMLNQIPNDYQSSRNQPGP------PGPPGPPGSAGARGEPGPGGRPGFP 2968
                               +  +R  PGP      PGPPGP GS G  G PGP G  G P
Sbjct: 874  -------------------FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914

Query: 2969 GTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQG----ESRTGPPGSTGSRGPPG 3024
            G+PG+ GP G+ G PGEKG    G+ GP G PGP G  G        GPPG  G RG PG
Sbjct: 915  GSPGVSGPKGDAGQPGEKG--SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG 972

Query: 3025 P---------PGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
            P         PG  G SG RGPPGP G    +  A  P    G PGS
Sbjct: 973  PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP-GRDGNPGS 1018



 Score =  250 bits (638), Expect = 2e-65
 Identities = 147/330 (44%), Positives = 167/330 (50%), Gaps = 27/330 (8%)

Query: 2724 PSRRDEGKCPAFPNSC--TCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGD 2781
            P  + EG  P  P       +    G  GPPGPAG PGA G  GE G  G  G PG +G+
Sbjct: 776  PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE 835

Query: 2782 IGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDR 2841
             GPPG  GPPG  GP G   PG QG +G +G  G PG  G  G  GLPGPPG  G PG  
Sbjct: 836  GGPPGVAGPPGGSGPAGP--PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893

Query: 2842 GFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDH---------GRPGPSGLKGEK 2892
            G +G  G  GP GP G  G+PGSPGV+GP G  G+PG+          G PGP G+ G  
Sbjct: 894  GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT 953

Query: 2893 GDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGS 2952
            G RG +A    M         Q + G+  +         N     R   GPPGP G PG 
Sbjct: 954  GARG-LAGPPGMPGPRGSPGPQGVKGESGKPG------ANGLSGER---GPPGPQGLPGL 1003

Query: 2953 AGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTG 3012
            AG  GEPG  G PG  G PG  G PG +G  GE G    G+ G  G PGPPGP G +  G
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG--SPGAPGAPGHPGPPGPVGPA--G 1059

Query: 3013 PPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
              G  G  GP GP G PG +G RG PGP G
Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQG 1089



 Score =  247 bits (630), Expect = 1e-64
 Identities = 145/329 (44%), Positives = 163/329 (49%), Gaps = 40/329 (12%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIG------------PPGPRGDIGPPGPQGPPGPQ 2794
            GPPG  GPAG PG +G +GERG  G  G            PPG  G+ GPPGP G PG  
Sbjct: 843  GPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD 902

Query: 2795 GPNG----LSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAM 2850
            GP G       PG  G  G KGDAG+PG     G+PG  GPPG  GP G  G TG  G  
Sbjct: 903  GPPGPAGNTGAPGSPGVSGPKGDAGQPG---EKGSPGAQGPPGAPGPLGIAGITGARGLA 959

Query: 2851 GPRGPPGPPGSPGSPGVTGPSGKPGK---PGDHGRPGPSGLKGEKGDRGDIASQNMMRAV 2907
            GP G PGP GSPG  GV G SGKPG     G+ G PGP GL G  G  G+        + 
Sbjct: 960  GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019

Query: 2908 ARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGF 2967
                 +    G+ +R        P     +   PGPPGP GP G +G RGE GP G  G 
Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPG----APGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075

Query: 2968 PGTPGMQGPPGERGLPGEKGERG----------TGSSGPRGLPGPPGPQGE----SRTGP 3013
            PG  G +G PG +G  G+KGE G           G  G  G PG PGP G+       GP
Sbjct: 1076 PGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP 1135

Query: 3014 PGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             G  G  GP GPPG+ G SG  GP GPPG
Sbjct: 1136 AGPRGPVGPSGPPGKDGTSGHPGPIGPPG 1164



 Score =  245 bits (625), Expect = 6e-64
 Identities = 158/366 (43%), Positives = 173/366 (47%), Gaps = 63/366 (17%)

Query: 2746 VGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQ------------GPPGP 2793
            +G PGP G  G PG  G RG  G  G  GPPG  G+ GP GP             GPPGP
Sbjct: 578  MGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637

Query: 2794 QGPNGL----SIPGEQGR---QGMKGDAGEPGLPGRTGTPGLP---GPPGPMGPPGDRGF 2843
            QG  GL      PGE G+    G KGDAG PG PG  G  G P   GPPG  G PG RG 
Sbjct: 638  QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697

Query: 2844 TGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIASQ 2901
             G  G  G +G  GPPG PG+ G  G  G PG+ G  G PGP G KGE G  G   +  +
Sbjct: 698  AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757

Query: 2902 NMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGP 2961
            +  R     +     +GQ           P D +     PG PG  GP GS G RGE GP
Sbjct: 758  DGPRGPTGPIGPPGPAGQ-----------PGD-KGEGGAPGLPGIAGPRGSPGERGETGP 805

Query: 2962 GGRPGFPGTPGMQGPP---GERGLPGEKGERG-------TGSSGPRGLPGPPGPQGESRT 3011
             G  GFPG PG  G P   GERG PGEKGE G        G SGP G PGP G +GE  +
Sbjct: 806  PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGS 865

Query: 3012 ----------------GPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYN 3055
                            GPPGS G+ GPPGP G PG  G  GP G  G    S   S P  
Sbjct: 866  PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTG-APGSPGVSGPKG 924

Query: 3056 GQGYPG 3061
              G PG
Sbjct: 925  DAGQPG 930



 Score =  239 bits (611), Expect = 2e-62
 Identities = 138/330 (41%), Positives = 160/330 (48%), Gaps = 20/330 (6%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLS-IPGEQ 2805
            GPPGP G  G PG +G  GE G +GA G PGPRG+ G  G  G PG +G +G    PGE 
Sbjct: 414  GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473

Query: 2806 GRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSP 2865
            G  G+ G AGE G PG  G  G  G PG  GP G+RG  G  G  G  G PG  G PG P
Sbjct: 474  GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533

Query: 2866 GVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIA-----SQNMMRAVARQVCEQLISGQM 2920
            G+ G  G PG PG  G+PGP G +GE G  G         Q  +             G+ 
Sbjct: 534  GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593

Query: 2921 NRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGER 2980
                      P        + GP GPPGP G  G +G+ GP G  G  G PG  GPPGE 
Sbjct: 594  GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGEN 653

Query: 2981 GLPGEKGERGTGSSGPRGLPGPPGPQGES----RTGPPGSTGS---RGPPGPPGRPGNSG 3033
            G PGE G +G       G PG PG +G++      GPPG  G+   RG  GPPG  G  G
Sbjct: 654  GKPGEPGPKGDA-----GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708

Query: 3034 IRGPPGPPGYCDSSQCASIP--YNGQGYPG 3061
              GPPGPPG   +     +P    G G PG
Sbjct: 709  AAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738



 Score =  234 bits (596), Expect = 1e-60
 Identities = 143/354 (40%), Positives = 166/354 (46%), Gaps = 37/354 (10%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-------L 2799
            G PGP GP G PG +G  G  G +GA G  G RG  G PGP GPPG  G  G       +
Sbjct: 294  GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRG------FTGKDGAMGPR 2853
               G  G  G  G  GEPG  G  G  G PGPPG  G PG +G        G  G MG R
Sbjct: 354  GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGAR 413

Query: 2854 GPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRG--DIASQNMMRAVARQV 2911
            GPPGP G+ G+PG+ G +G+PGK G  G PGP G +GE G  G      ++       + 
Sbjct: 414  GPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEP 473

Query: 2912 CEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTP 2971
                + G          + P        + GP G  G PG AG RG  G  GR G PG P
Sbjct: 474  GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533

Query: 2972 GMQGPPGERGLPGEKGERG-TGSSGPRGLPGPPGPQG-------------ESRTGPPGST 3017
            GM+G PG  G PG  G+ G  GS G  G PGPPGP G             +   G PG  
Sbjct: 534  GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593

Query: 3018 GSR------GPPGPPGRPGNSGIRGPPGP--PGYCDSSQCASIPYNGQGYPGSG 3063
            G R      GP GPPG+ G +G +GPPGP  PG          P   QG PG+G
Sbjct: 594  GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647



 Score =  231 bits (589), Expect = 8e-60
 Identities = 141/332 (42%), Positives = 161/332 (48%), Gaps = 28/332 (8%)

Query: 2750 GPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQG 2809
            GP GP G PG KGP GERG   A GP GPRG  G PG  G PG  G  G+  PG  G  G
Sbjct: 492  GPAGPNGIPGEKGPAGERG---APGPAGPRGAAGEPGRDGVPGGPGMRGM--PGSPGGPG 546

Query: 2810 MKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTG 2869
              G  G PG  G +G PG PGP GP G PG  GF G  G  G  G  G  G PG PG  G
Sbjct: 547  SDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606

Query: 2870 PSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNM--MRAVARQVCEQLISGQMNRFNQML 2927
            P GK G+ G  G PGP+G  G+KGD G    Q +  +        E    G+        
Sbjct: 607  PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666

Query: 2928 NQIPNDYQSSRNQPGPPGPP------------GPPGSAGARGEPGPGGRPGFPGTPGMQG 2975
                   +     PG  GPP            GPPG  G +G  GP G PG  GTPG+QG
Sbjct: 667  APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726

Query: 2976 PPGER---GLPGEKGERG-TGSSGPRGLPGPPGPQGES-RTGPPGSTGSRGPPGPPGRPG 3030
             PGER   G PG KG++G  G  G  G+PG  GP+G +   GPPG  G  G  G  G PG
Sbjct: 727  MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786

Query: 3031 NSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
              GI GP G PG     +  + P    G+PG+
Sbjct: 787  LPGIAGPRGSPG----ERGETGPPGPAGFPGA 814



 Score =  229 bits (584), Expect = 3e-59
 Identities = 152/398 (38%), Positives = 167/398 (41%), Gaps = 81/398 (20%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGE---------RGISGAIGPPGPRGDIG 2783
            PA PN     +   G  G PGPAG  GA G  G          RG+ G+ G PG  G  G
Sbjct: 493  PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPG 552

Query: 2784 PPGPQG------PPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGP--- 2834
            PPG QG      PPGP GP G   PG  G  G KG+ G PG  G  G PG PGP GP   
Sbjct: 553  PPGSQGESGRPGPPGPSGPRGQ--PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610

Query: 2835 ---MGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGE 2891
                GP G  G TG  G  G  GPPGP G  G PG  GP G+ GKPG+ G  G +G  G 
Sbjct: 611  NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670

Query: 2892 KGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGP-- 2949
             G +GD  +              L  G            P   +  +   GPPGPPG   
Sbjct: 671  PGGKGDAGAPGERGPPGLAGAPGLRGGAG----------PPGPEGGKGAAGPPGPPGAAG 720

Query: 2950 -------PGSAGARGEPGPGGRPGFPGTPGMQ---------------GPPGERGLPGEKG 2987
                   PG  G  G PGP G  G PG PG                 GPPG  G PG+KG
Sbjct: 721  TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG 780

Query: 2988 ERG-------------------TGSSGPRGLPGPPG----PQGESRTGPPGSTGSRGPPG 3024
            E G                   TG  GP G PG PG    P G+   G PG  G  GPPG
Sbjct: 781  EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840

Query: 3025 PPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGS 3062
              G PG SG  GPPGP G          P    G+PG+
Sbjct: 841  VAGPPGGSGPAGPPGPQGVKGERGSPGGP-GAAGFPGA 877



 Score =  229 bits (583), Expect = 4e-59
 Identities = 143/353 (40%), Positives = 167/353 (47%), Gaps = 47/353 (13%)

Query: 2732 CPAFPNSCTCTQDSVGPPGP---PGPAGGPGAKGPRGERGISGAIGPPGPRG-------- 2780
            CP  P + T   +  GP GP   PGP G PG  G  G  G  G+ G PGP G        
Sbjct: 88   CPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG 147

Query: 2781 -----------DI----------GPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGL 2819
                       D+          G PGP GPPGP GP G S  G  G  G  G  G PG 
Sbjct: 148  PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS--GHPGSPGSPGYQGPPGE 205

Query: 2820 PGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGD 2879
            PG+ G  G PGPPG +GP G     GKDG  G  G PG  G PG PG+ GP+G PG PG 
Sbjct: 206  PGQAGPSGPPGPPGAIGPSGP---AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGM 262

Query: 2880 HGRPGPSGLKGEKGDRG--DIASQNMM---RAVARQVCEQLISGQMNRFNQMLNQIPNDY 2934
             G  G  G  GEKG+ G   +  +N +         +  +   G+  R            
Sbjct: 263  KGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322

Query: 2935 QSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGT-GS 2993
              +R   G PGPPGPPG+AG  G PG  G  G  G+PG  G PG+RG PG +G  G  G 
Sbjct: 323  DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382

Query: 2994 SGPRGLPGPPGPQGE----SRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPG 3042
             GP G+ G PG +GE       G PG  G+RGPPGP G  G  G+RG  G PG
Sbjct: 383  PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435



 Score =  211 bits (536), Expect = 1e-53
 Identities = 123/292 (42%), Positives = 139/292 (47%), Gaps = 65/292 (22%)

Query: 2747 GPPGPPGPAGGPGAKGPRGE------RGISGAIGPPGPRGDIGPPGPQGPPGPQG-PNGL 2799
            GPPG PGP G PG +G +GE       G+SG  GPPGP+G  G  G  G PG  G P   
Sbjct: 960  GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019

Query: 2800 SIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPP 2859
             +PG  G  G KGD GE G PG  G PG PGPPGP+GP G  G  G+ G  GP G PGP 
Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPA 1079

Query: 2860 GSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQ 2919
            GS G+PG  GP G  G+ G+    G +G+KG +G  G+                      
Sbjct: 1080 GSRGAPGPQGPRGDKGETGER---GAAGIKGHRGFPGN---------------------- 1114

Query: 2920 MNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGE 2979
                                 PG PG PGP G  GA G PGP G     G  G  GPPG+
Sbjct: 1115 ---------------------PGAPGSPGPAGQQGAIGSPGPAGP---RGPVGPSGPPGK 1150

Query: 2980 RGLPGEKGERGTGSSGPRGLPGPPGPQGE-SRTGPPGSTGSRGPPGPPGRPG 3030
             G  G          GP G PGP G +GE    G PG  G  GPPGPPG PG
Sbjct: 1151 DGTSGH--------PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194



 Score =  205 bits (521), Expect = 6e-52
 Identities = 138/371 (37%), Positives = 163/371 (43%), Gaps = 60/371 (16%)

Query: 2720 CCDIPSRRDEGKCP----AFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGP 2775
            C DI     E  CP     F   C     +V P  P  P   P  +GP+G +G  G  G 
Sbjct: 62   CDDIICDDQELDCPNPEIPFGECC-----AVCPQPPTAPTRPPNGQGPQGPKGDPGPPGI 116

Query: 2776 PGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPM 2835
            PG  GD G PG  G PG  GP G+      G Q          +       GL G PGP 
Sbjct: 117  PGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPA 176

Query: 2836 GP---------------PGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGP------SGKP 2874
            GP               PG  G+ G  G  G  GP GPPG PG+ G +GP      SG+P
Sbjct: 177  GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236

Query: 2875 GKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDY 2934
            G+PG+ G PGP G+KG  G  G        R    +  E+  +G      +  N +P + 
Sbjct: 237  GRPGERGLPGPPGIKGPAGIPG-FPGMKGHRGFDGRNGEKGETGAPGLKGE--NGLPGEN 293

Query: 2935 -----QSSRNQPGPPGPPGPPGSAGARGE------------PGPGGRPGFPGTPGMQ--- 2974
                    R  PG  G PG PG+AGARG             PGP G  GFPG+PG +   
Sbjct: 294  GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 2975 ---GPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGN 3031
               G PG  G PG++GE   G  G  G  GPPGP G +  G PG  G  GP G PG PG 
Sbjct: 354  GPAGSPGSNGAPGQRGE--PGPQGHAGAQGPPGPPGIN--GSPGGKGEMGPAGIPGAPGL 409

Query: 3032 SGIRGPPGPPG 3042
             G RGPPGP G
Sbjct: 410  MGARGPPGPAG 420



 Score =  148 bits (373), Expect = 9e-35
 Identities = 78/156 (50%), Positives = 84/156 (53%), Gaps = 10/156 (6%)

Query: 2745 SVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNG-LSIPG 2803
            S G PG PG  G PG  GP G+ G  G  GP GP G  GP G +G PGPQGP G     G
Sbjct: 1039 SPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETG 1098

Query: 2804 EQGRQGMKGDAGEPGLPGRTGTP---------GLPGPPGPMGPPGDRGFTGKDGAMGPRG 2854
            E+G  G+KG  G PG PG  G+P         G PGP GP GP G  G  GKDG  G  G
Sbjct: 1099 ERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPG 1158

Query: 2855 PPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKG 2890
            P GPPG  G+ G  G  G PG PG  G PGP G  G
Sbjct: 1159 PIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194



 Score =  141 bits (356), Expect = 9e-33
 Identities = 93/239 (38%), Positives = 108/239 (45%), Gaps = 54/239 (22%)

Query: 2813 DAGEPGLPGRTGTPGLPGPP-GPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPS 2871
            D   P +P        P PP  P  PP  +G         P+GP G PG PG PG  G  
Sbjct: 73   DCPNPEIPFGECCAVCPQPPTAPTRPPNGQG---------PQGPKGDPGPPGIPGRNGDP 123

Query: 2872 GKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIP 2931
            G PG+PG  G PGP G                       +CE   +G  N   Q  +   
Sbjct: 124  GIPGQPGSPGSPGPPG-----------------------ICESCPTGPQNYSPQYDSY-- 158

Query: 2932 NDYQSS------RNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGE 2985
             D +S          PGP GPPGPPG       PG  G PG PG+PG QGPPGE   PG+
Sbjct: 159  -DVKSGVAVGGLAGYPGPAGPPGPPGP------PGTSGHPGSPGSPGYQGPPGE---PGQ 208

Query: 2986 KGERGTGSSGPRGLPGPPGPQG-ESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGY 3043
             G   +G  GP G  GP GP G +  +G PG  G RG PGPPG  G +GI G PG  G+
Sbjct: 209  AGP--SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH 265



 Score =  139 bits (349), Expect = 6e-32
 Identities = 77/171 (45%), Positives = 87/171 (50%), Gaps = 30/171 (17%)

Query: 2747 GPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQG 2806
            G PGPPGP G  G  G RGE G +G  G PGP G  G PGPQGP G +G  G     E+G
Sbjct: 1047 GHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETG-----ERG 1101

Query: 2807 RQGMKGDAGEPGLPGRTGTPGLPG---------------PPGPMGPPGDRGFTGKDGAMG 2851
              G+KG  G PG PG  G+PG  G               P GP GPPG  G +G  G +G
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIG 1161

Query: 2852 PRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGP----------SGLKGEK 2892
            P GP G  G  GS G  G  G+PG PG  G PGP          +G+ GEK
Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212



 Score = 96.7 bits (239), Expect = 3e-19
 Identities = 56/128 (43%), Positives = 59/128 (46%), Gaps = 23/128 (17%)

Query: 2733 PAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISG--------------------- 2771
            PA P        S G PGP GP G  G  G RG  GI G                     
Sbjct: 1069 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG 1128

Query: 2772 AIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGP 2831
            AIG PGP G  GP GP GPPG  G +G   PG  G  G +G+ GE G  G  G PG PGP
Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPGKDGTSG--HPGPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186

Query: 2832 PGPMGPPG 2839
            PGP G PG
Sbjct: 1187 PGPPGAPG 1194



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 50/126 (39%), Positives = 60/126 (47%), Gaps = 17/126 (13%)

Query: 2931 PNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQG-----PPGERGLPGE 2985
            P    + +   GP G PGPPG  G  G+PG  G+PG PG+PG  G     P G +    +
Sbjct: 95   PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ 154

Query: 2986 KG----ERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPP 3041
                  + G    G  G PGP GP G     PPG  G+ G PG PG PG    +GPPG P
Sbjct: 155  YDSYDVKSGVAVGGLAGYPGPAGPPG-----PPGPPGTSGHPGSPGSPG---YQGPPGEP 206

Query: 3042 GYCDSS 3047
            G    S
Sbjct: 207  GQAGPS 212



 Score = 56.6 bits (135), Expect = 4e-07
 Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 7/65 (10%)

Query: 2991 TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCA 3050
            T  + P    GP GP+G+   GPPG  G  G PG PG+PG+ G    PGPPG C+S  C 
Sbjct: 93   TAPTRPPNGQGPQGPKGDP--GPPGIPGRNGDPGIPGQPGSPG---SPGPPGICES--CP 145

Query: 3051 SIPYN 3055
            + P N
Sbjct: 146  TGPQN 150


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.133    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 142,390,407
Number of Sequences: 37866
Number of extensions: 8746169
Number of successful extensions: 182842
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 506
Number of HSP's successfully gapped in prelim test: 1442
Number of HSP's that attempted gapping in prelim test: 34011
Number of HSP's gapped (non-prelim): 29108
length of query: 3063
length of database: 18,247,518
effective HSP length: 121
effective length of query: 2942
effective length of database: 13,665,732
effective search space: 40204583544
effective search space used: 40204583544
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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