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Search of human proteins with 7662302
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662302 TBK1 binding protein 1 [Homo sapiens]
(615 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 1259 0.0
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 75 2e-13
gi|33356148 formin-like 1 [Homo sapiens] 75 2e-13
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 71 3e-12
gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens] 70 6e-12
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 69 1e-11
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 69 1e-11
gi|46852390 coiled-coil domain containing 6 [Homo sapiens] 69 1e-11
gi|153792074 proline rich 12 [Homo sapiens] 68 3e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 2e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 65 2e-10
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 64 4e-10
gi|222418649 mucin 7, secreted precursor [Homo sapiens] 64 4e-10
gi|222418645 mucin 7, secreted precursor [Homo sapiens] 64 4e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 5e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 5e-10
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 64 5e-10
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 64 5e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 63 7e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens] 63 7e-10
gi|18079216 CASK interacting protein 1 [Homo sapiens] 63 9e-10
gi|157168329 formin 1 [Homo sapiens] 62 2e-09
gi|54860079 nadrin isoform 1 [Homo sapiens] 62 2e-09
gi|54860105 nadrin isoform 2 [Homo sapiens] 62 2e-09
gi|55741677 SET domain containing 1A [Homo sapiens] 62 2e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is... 62 2e-09
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 61 3e-09
gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens] 61 3e-09
gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens] 61 3e-09
gi|18959210 WIRE protein [Homo sapiens] 61 3e-09
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 1259 bits (3259), Expect = 0.0
Identities = 615/615 (100%), Positives = 615/615 (100%)
Query: 1 MESMFEDDISILTQEALGPSEVWLDSPGDPSLGGDMCSASHFALITAYGDIKERLGGLER 60
MESMFEDDISILTQEALGPSEVWLDSPGDPSLGGDMCSASHFALITAYGDIKERLGGLER
Sbjct: 1 MESMFEDDISILTQEALGPSEVWLDSPGDPSLGGDMCSASHFALITAYGDIKERLGGLER 60
Query: 61 ENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKN 120
ENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKN
Sbjct: 61 ENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKN 120
Query: 121 KEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAF 180
KEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAF
Sbjct: 121 KEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAF 180
Query: 181 SNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEA 240
SNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEA
Sbjct: 181 SNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEA 240
Query: 241 RGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTE 300
RGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTE
Sbjct: 241 RGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTE 300
Query: 301 LTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPC 360
LTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPC
Sbjct: 301 LTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPC 360
Query: 361 PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPS 420
PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPS
Sbjct: 361 PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPS 420
Query: 421 CPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQ 480
CPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQ
Sbjct: 421 CPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQ 480
Query: 481 AEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTI 540
AEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTI
Sbjct: 481 AEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTI 540
Query: 541 RCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDD 600
RCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDD
Sbjct: 541 RCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDD 600
Query: 601 ALIKHIDSHLENSKI 615
ALIKHIDSHLENSKI
Sbjct: 601 ALIKHIDSHLENSKI 615
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 74.7 bits (182), Expect = 2e-13
Identities = 77/264 (29%), Positives = 106/264 (40%), Gaps = 27/264 (10%)
Query: 332 QRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASP-- 389
+RHSP S+ SP+P+ R P P +RRSP P P P++RR+P P
Sbjct: 521 RRHSP-SRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP-SPAPPPRRRRTPTPPPR 578
Query: 390 -SCPSPVPQRRSPVP----PSCQ-----SPSPQRRSPVPPSCPAPQPRPPPP-------- 431
PSP P+RRSP P P Q SP P+RR+ PP P + P PP
Sbjct: 579 RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHS 638
Query: 432 PPPGERT--LAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKP 489
PPP +R+ + +R S H K R + + + P +A + P
Sbjct: 639 PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698
Query: 490 RAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGF 549
P R SP + IR R + P E + SP V + + +G
Sbjct: 699 PVRRGASSSPQRRQSPSPSTRPIR-RVSRTP-EPKKIKKAASPSPQSVRRVSSSRSVSGS 756
Query: 550 PIPESPAATAYAHAEHAQSWPSIN 573
P P + A +QS PS N
Sbjct: 757 PEPAAKKPPAPPSPVQSQS-PSTN 779
Score = 52.0 bits (123), Expect = 2e-06
Identities = 44/133 (33%), Positives = 56/133 (42%), Gaps = 16/133 (12%)
Query: 328 RSGGQRHSPLSQRHSPAPQC-PSP---SPPARAAPPCPPCQSPVP---QRRSPVPPCPSP 380
RS + +SP R P+P+ PSP +PP R PP +S P +RRS S
Sbjct: 303 RSRSRSYSP---RRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSS 359
Query: 381 QQRRSPASPSCPSPVPQRRSPVPPSCQ------SPSPQRRSPVPPSCPAPQPRPPPPPPP 434
S S S P P+R S P + SP +R P PP+ P P+ R P P
Sbjct: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419
Query: 435 GERTLAERAYAKP 447
RT R P
Sbjct: 420 SNRTRKSRVSVSP 432
Score = 51.6 bits (122), Expect = 2e-06
Identities = 56/204 (27%), Positives = 79/204 (38%), Gaps = 35/204 (17%)
Query: 320 RTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPP--CQSPVPQRR--SPVP 375
R+ + ++ +RHSP + APQ S PP R P QSP P R V
Sbjct: 668 RSTREARSPQPNKRHSPSPRPR--APQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVS 725
Query: 376 PCPSPQQRRSPASPS-------------CPSPVP-QRRSPVPPS-CQSPSPQRR-SPVPP 419
P P++ + ASPS SP P ++ P PPS QS SP SP P
Sbjct: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
Query: 420 SCPAPQPRPPPPPPPG---------ERTLAERAYAKPPSHHVKAGFQGRRSYSELAEG-- 468
A P P P PP ++ ++ + K H + ++ + A
Sbjct: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAV 845
Query: 469 --AAYAGASPPWLQAEAATLPKPR 490
AA A A+ Q E P+P+
Sbjct: 846 TPAAIAAATTTLAQEEPVAAPEPK 869
Score = 45.4 bits (106), Expect = 2e-04
Identities = 55/223 (24%), Positives = 77/223 (34%), Gaps = 20/223 (8%)
Query: 320 RTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPS 379
R+ ++ + RS S S + P PP R + P P++ + P S
Sbjct: 342 RSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP--------PRKTRRLSPSAS 393
Query: 380 PQQRRSPASPSCPSPVPQRRSPVP-------PSCQSPSPQRRSPVPPSCPAPQPR--PPP 430
P +RR SP P R SP P S S SP R S + R P P
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453
Query: 431 PPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPR 490
P P + L+E K Q RR Y + ++ S + E PK
Sbjct: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER---PKRS 510
Query: 491 AYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPP 533
+ G R SP R+ + +K+ S SPP
Sbjct: 511 HVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPP 553
Score = 41.2 bits (95), Expect = 0.003
Identities = 71/303 (23%), Positives = 111/303 (36%), Gaps = 38/303 (12%)
Query: 248 EQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGR 307
+Q Q E E+L KQ ++ +D +S R+ R + + + + + + R
Sbjct: 132 KQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRR 191
Query: 308 LRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPS-----PPARAAPPCP- 361
R+ S + RT ++RS SP ++ P+ P PS P + A
Sbjct: 192 ERKRSHSRSPRHRT----KSRSP----SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSD 243
Query: 362 ----PCQSPVPQRRSPVPPCPSPQQRRS----PASPSCPSPVPQRRSPVPPSCQSPSPQR 413
P P+P+ + P P S +++ P S S + RS PS P +
Sbjct: 244 ILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR-SPSHTRPRRRH 302
Query: 414 RSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAG 473
RS P +P P P P RT R PP H ++ RR A+ +G
Sbjct: 303 RSRSRSYSPRRRPSPRRRPSPRRRTPPRR--MPPPPRHRRSRSPVRR---RRRSSASLSG 357
Query: 474 ASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPP 533
+S + + + PK P R SP R RL P P + P
Sbjct: 358 SSSSSSSSRSRSPPKK--------PPKRTSSPPRKTR--RLSPSASPPRRRHRPSPPATP 407
Query: 534 SPE 536
P+
Sbjct: 408 PPK 410
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 74.7 bits (182), Expect = 2e-13
Identities = 67/217 (30%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 229 LEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVG 288
L E L A+ E+ + +L+ + + + EL+ L+E ++ A S R K
Sbjct: 411 LTERLRDAENESMA---KIAELEKQLSQARKELETLRERFSESTAMGASRRPPEPEKAPP 467
Query: 289 DDQVN---LALAYTELTEELGRLRELSSLQGRILRTLLQEQAR--SGGQRHSPLSQRHSP 343
L L EL EE G +R L + +L SGG +P SP
Sbjct: 468 AAPTRPSALELKVEEL-EEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSP 526
Query: 344 APQ-CPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCP----SPVPQR 398
+P P+ P AAPP PP P+P PSPQ+ A P P SP P
Sbjct: 527 SPDLAPAAEPAPGAAPPPPP----------PLPGLPSPQEAPPSAPPQAPPLPGSPEPPP 576
Query: 399 RSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPG 435
P+P P P P P P P PPPPPPPG
Sbjct: 577 APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPG 613
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 71.2 bits (173), Expect = 3e-12
Identities = 64/206 (31%), Positives = 85/206 (41%), Gaps = 33/206 (16%)
Query: 255 ERLQGELKQLQETRAQ-DLASN-QSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELS 312
E+ +G+ K+ + T+A SN Q + W G D NL L + G + E
Sbjct: 187 EKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG-ISEAQ 245
Query: 313 SLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRS 372
+ + ++GG + ++ Q P P PP+R PP PP P P
Sbjct: 246 LKDRETSKVIYDFIEKTGGVE----AVKNELRRQAPPPPPPSRGGPPPPP---PPPHNSG 298
Query: 373 PVPP------CPSPQQRRSPAS------PSCPS----PVPQRR--SPVPPSCQSPSPQRR 414
P PP P P R+P + PS PS P P R P PP+ S +P
Sbjct: 299 PPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGP 358
Query: 415 SPVPPSC-----PAPQPRPPPPPPPG 435
P PPS AP P PPPPPPPG
Sbjct: 359 PPPPPSVLGVGPVAPPPPPPPPPPPG 384
Score = 66.2 bits (160), Expect = 8e-11
Identities = 38/101 (37%), Positives = 42/101 (41%), Gaps = 10/101 (9%)
Query: 343 PAPQCPSPSPP---ARAAPPCPPCQSPV-------PQRRSPVPPCPSPQQRRSPASPSCP 392
P P P PP R APP PP ++P P R S P P P + P P+ P
Sbjct: 292 PPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALP 351
Query: 393 SPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPP 433
S P P PPS P P PP P P P PPP P
Sbjct: 352 SSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/110 (38%), Positives = 47/110 (42%), Gaps = 24/110 (21%)
Query: 327 ARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSP 386
AR G P S+ + AP P PS P+ A PP P P R P PP P
Sbjct: 304 ARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP------PPPNRMYPPPPPALPS----- 352
Query: 387 ASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPP-PPPPPG 435
++PS P P P PS PV P P P P PP PPPPPG
Sbjct: 353 SAPSGPPPPP------------PSVLGVGPVAPPPPPPPPPPPGPPPPPG 390
>gi|11968003 5-azacytidine induced 2 isoform a [Homo sapiens]
Length = 392
Score = 70.1 bits (170), Expect = 6e-12
Identities = 82/330 (24%), Positives = 136/330 (41%), Gaps = 91/330 (27%)
Query: 1 MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 59
M+++ EDDI IL E D+ S+ GD ASHFAL+TAY DIK+RL E
Sbjct: 1 MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE 56
Query: 60 RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQK 119
+EN+ L++R++ E K LI+ F EE
Sbjct: 57 KENSLLKKRIRFLEEK--LIARFEEE---------------------------------T 81
Query: 120 NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQ--- 176
+ EQ+ + AY ++C+++ +L+++L +M L+ + + Q ++ + LQ
Sbjct: 82 SSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLK-VLNEQLQSKEVELLQLRT 140
Query: 177 ----DAAFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEA 232
NL+PP + W S DL+ LE+
Sbjct: 141 EVETQQVMRNLNPP------------------------SSNWEVEKLS-CDLKIHGLEQE 175
Query: 233 LEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQV 292
LE ++ EC L+ EL++ ++T N RD+ +++
Sbjct: 176 LEL--------------MRKECSDLKIELQKAKQTDPYQ-EDNLKSRDL---QKLSISSD 217
Query: 293 NLALAYTELTEELGRLRELSSLQGRILRTL 322
N+ AY EL E+ L ++ +Q +LR L
Sbjct: 218 NMQHAYWELKREMSNLHLVTQVQAELLRKL 247
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 69.3 bits (168), Expect = 1e-11
Identities = 52/153 (33%), Positives = 62/153 (40%), Gaps = 19/153 (12%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPS--------PQQRRSPA 387
P P P P PS ++A PP PP P P P+PP S PQ+ S +
Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP---PLPPSSSGNDETPRLPQRNLSLS 342
Query: 388 SPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERT-LAERAYAK 446
S + P P P R P+PP P R P P P + P PPPPP R RA
Sbjct: 343 SSTPPLPSPGRSGPLPPP-----PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 447 PPSHHVKAGFQGRRS--YSELAEGAAYAGASPP 477
P ++G RS L AGA PP
Sbjct: 398 TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Score = 60.1 bits (144), Expect = 6e-09
Identities = 73/255 (28%), Positives = 91/255 (35%), Gaps = 57/255 (22%)
Query: 330 GGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASP 389
G R SPLS + + P P P+RA PP PP P R S
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP------------PPPPPVGNRPSIHRE 280
Query: 390 SCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPG----------ERTL 439
+ P P PQ P PS PS ++P PP P +P PPP PP +R L
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPP-PPSRPGPPPLPPSSSGNDETPRLPQRNL 339
Query: 440 AERAYAKPPSHHVKAG----FQGRRSYSELAEGAAYAGASPP---------WLQAEAAT- 485
+ + P ++G R + + +G PP +A AT
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399
Query: 486 -LPKPRAYGSELYGPGRPLSPRRAFEG----------IRLRFEKQPSEEDEWAV-----P 529
LP S GP PL P R G IR F+ P EDEW P
Sbjct: 400 QLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPC-EDEWESRFYFHP 458
Query: 530 TS---PPSPEVGTIR 541
S PP P V T +
Sbjct: 459 ISDLPPPEPYVQTTK 473
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/126 (34%), Positives = 50/126 (39%), Gaps = 11/126 (8%)
Query: 319 LRTLLQEQARSGGQRHS--PLSQRHSPAPQCPSPSPPARAAPPCPPCQS--PVPQRRSPV 374
LR+ SGG R P R + A PS P R P P +S P PQR
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170
Query: 375 PPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPP 434
PP P + S P PVP P+ SP + PVP P P P PPP P
Sbjct: 171 PPRPDVGSKPD----SIPPPVPSTPRPIQ---SSPHNRGSPPVPGGPRQPSPGPTPPPFP 223
Query: 435 GERTLA 440
G R A
Sbjct: 224 GNRGTA 229
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/112 (34%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 329 SGGQRHSPLSQRHSPAPQCPSPSP-PARAAP-PCPPCQSPVPQ------RRSPVPPCPSP 380
SG L QR+ P P P R+ P P PP + P P R P+PP P P
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP-PPP 384
Query: 381 QQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPP 432
R S + P+ PQ P SP R P+PP P+ PPPPP
Sbjct: 385 VSRNGSTSRALPA-TPQ--LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
Score = 30.4 bits (67), Expect = 5.0
Identities = 28/97 (28%), Positives = 33/97 (34%), Gaps = 11/97 (11%)
Query: 338 SQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSC----PS 393
S R P P P P A A PP PP S + PC + R P P
Sbjct: 409 SPRSGPRPPLPPDRPSAGAPPPPPPSTS--IRNGFQDSPCEDEWESRFYFHPISDLPPPE 466
Query: 394 PVPQRRSPVPP-----SCQSPSPQRRSPVPPSCPAPQ 425
P Q P +S S +R PP P P+
Sbjct: 467 PYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 69.3 bits (168), Expect = 1e-11
Identities = 52/153 (33%), Positives = 62/153 (40%), Gaps = 19/153 (12%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPS--------PQQRRSPA 387
P P P P PS ++A PP PP P P P+PP S PQ+ S +
Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP---PLPPSSSGNDETPRLPQRNLSLS 342
Query: 388 SPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERT-LAERAYAK 446
S + P P P R P+PP P R P P P + P PPPPP R RA
Sbjct: 343 SSTPPLPSPGRSGPLPPP-----PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPA 397
Query: 447 PPSHHVKAGFQGRRS--YSELAEGAAYAGASPP 477
P ++G RS L AGA PP
Sbjct: 398 TPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Score = 60.1 bits (144), Expect = 6e-09
Identities = 73/255 (28%), Positives = 91/255 (35%), Gaps = 57/255 (22%)
Query: 330 GGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASP 389
G R SPLS + + P P P+RA PP PP P R S
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP------------PPPPPVGNRPSIHRE 280
Query: 390 SCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPG----------ERTL 439
+ P P PQ P PS PS ++P PP P +P PPP PP +R L
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPP-PPSRPGPPPLPPSSSGNDETPRLPQRNL 339
Query: 440 AERAYAKPPSHHVKAG----FQGRRSYSELAEGAAYAGASPP---------WLQAEAAT- 485
+ + P ++G R + + +G PP +A AT
Sbjct: 340 SLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP 399
Query: 486 -LPKPRAYGSELYGPGRPLSPRRAFEG----------IRLRFEKQPSEEDEWAV-----P 529
LP S GP PL P R G IR F+ P EDEW P
Sbjct: 400 QLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPC-EDEWESRFYFHP 458
Query: 530 TS---PPSPEVGTIR 541
S PP P V T +
Sbjct: 459 ISDLPPPEPYVQTTK 473
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/126 (34%), Positives = 50/126 (39%), Gaps = 11/126 (8%)
Query: 319 LRTLLQEQARSGGQRHS--PLSQRHSPAPQCPSPSPPARAAPPCPPCQS--PVPQRRSPV 374
LR+ SGG R P R + A PS P R P P +S P PQR
Sbjct: 111 LRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMP 170
Query: 375 PPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPP 434
PP P + S P PVP P+ SP + PVP P P P PPP P
Sbjct: 171 PPRPDVGSKPD----SIPPPVPSTPRPIQ---SSPHNRGSPPVPGGPRQPSPGPTPPPFP 223
Query: 435 GERTLA 440
G R A
Sbjct: 224 GNRGTA 229
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/112 (34%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
Query: 329 SGGQRHSPLSQRHSPAPQCPSPSP-PARAAP-PCPPCQSPVPQ------RRSPVPPCPSP 380
SG L QR+ P P P R+ P P PP + P P R P+PP P P
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP-PPP 384
Query: 381 QQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPP 432
R S + P+ PQ P SP R P+PP P+ PPPPP
Sbjct: 385 VSRNGSTSRALPA-TPQ--LPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433
Score = 30.4 bits (67), Expect = 5.0
Identities = 28/97 (28%), Positives = 33/97 (34%), Gaps = 11/97 (11%)
Query: 338 SQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSC----PS 393
S R P P P P A A PP PP S + PC + R P P
Sbjct: 409 SPRSGPRPPLPPDRPSAGAPPPPPPSTS--IRNGFQDSPCEDEWESRFYFHPISDLPPPE 466
Query: 394 PVPQRRSPVPP-----SCQSPSPQRRSPVPPSCPAPQ 425
P Q P +S S +R PP P P+
Sbjct: 467 PYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
>gi|46852390 coiled-coil domain containing 6 [Homo sapiens]
Length = 474
Score = 68.9 bits (167), Expect = 1e-11
Identities = 110/473 (23%), Positives = 178/473 (37%), Gaps = 135/473 (28%)
Query: 50 DIKERLGGLERENATLRRRLKVYEIKYPLISDFG----------------EEHGFSLYEI 93
++ RL L++EN L+ L+ Y++K + + EE S
Sbjct: 58 ELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLF 117
Query: 94 KDGSLLEVEKVSL---------------QQRLNQFQHE---LQKNKEQEE--QLGEMIQ- 132
K L+ EK +L ++L Q QHE L+++ EQE+ Q+ ++++
Sbjct: 118 KKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKK 177
Query: 133 -------------AYEKLCVEKSDLETEL-REMRALVETHLRQICGLEQQLRQQQGLQDA 178
E+L EK DLE L +E ALV +++ LE + R LQ+
Sbjct: 178 IKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRI---LQEK 234
Query: 179 AFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQG 238
+S PP+P ++D +P R L+ +E +
Sbjct: 235 LDQPVSAPPSPRDISMEID--------------------SPENMMRHIRFLKNEVERLKK 274
Query: 239 EARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAY 298
+ R AQL+ + A+ + +++ + R Q + ER A +++ + + +L +
Sbjct: 275 QLRAAQLQHSEKMAQYLEEERHMRE-ENLRLQRKLQREMERREALCRQLSESESSLEMDD 333
Query: 299 TELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAP 358
E+ S QG RT+ SP P PSPS ++
Sbjct: 334 ERYFNEM-------SAQGLRPRTV------------------SSPIPYTPSPS----SSR 364
Query: 359 PCPPCQSPVPQRRSPVPPC------------PSPQQRRSPASPSCPSPVPQR-------R 399
P P S PP P + S P P+R +
Sbjct: 365 PISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFK 424
Query: 400 SPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKP-PSHH 451
P PP PSP ++PV QP PPPPPPP + T+ A ++P PS H
Sbjct: 425 RPTPP----PSPNTQTPV-------QPPPPPPPPPMQPTVPSAATSQPTPSQH 466
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 67.8 bits (164), Expect = 3e-11
Identities = 67/214 (31%), Positives = 87/214 (40%), Gaps = 40/214 (18%)
Query: 232 ALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQ 291
ALEAA+ E G + C+RL ELK+ ET L S S+ + + K D Q
Sbjct: 1346 ALEAAESEGLGLGC-----PSPCKRLDEELKRNLET----LPSFSSDEEDSVAKN-RDLQ 1395
Query: 292 VNLALAYTELTEE-LGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSP 350
+++ A + L + L ++ S+ G L +P + P P P
Sbjct: 1396 ESISSAISALDDPPLAGPKDTSTPDGPPL---------------APAAAVPGPPPLPGLP 1440
Query: 351 SPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPS 410
S + P PP P P P P PQ P P P PQ P PP +P+
Sbjct: 1441 SANSNGTPE-PPLLEEKPPPTPPPAPTPQPQ-------PPPPPPPPQPALPSPPPLVAPT 1492
Query: 411 PQRRSPVPPSCPAP----QPRPPPPPPPGERTLA 440
P SP PP P P P PPPPPPP LA
Sbjct: 1493 PS--SPPPPPLPPPPPPAMPSPPPPPPPAAAPLA 1524
Score = 48.9 bits (115), Expect = 1e-05
Identities = 49/194 (25%), Positives = 59/194 (30%), Gaps = 88/194 (45%)
Query: 331 GQRHSPLSQRHSPAPQCPS----PSPPARAAPPCPPCQSPVPQRRSPVPP---------- 376
G+RH PL Q P P PS PAR P PP VP P P
Sbjct: 1292 GKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPH---PPPSGAFGLGGALE 1348
Query: 377 ----------CPSPQQR------------------------------------------- 383
CPSP +R
Sbjct: 1349 AAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDP 1408
Query: 384 -----RSPASPSCPSPVPQRRSPVPP---------SCQSPSP----QRRSPVPPSCPAPQ 425
+ ++P P P P PP S +P P ++ P PP P PQ
Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468
Query: 426 PRPPPPPPPGERTL 439
P+PPPPPPP + L
Sbjct: 1469 PQPPPPPPPPQPAL 1482
Score = 44.7 bits (104), Expect = 3e-04
Identities = 47/186 (25%), Positives = 73/186 (39%), Gaps = 9/186 (4%)
Query: 328 RSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPA 387
R GQ +P+S S AP +P+PP + P S P ++P P P +P
Sbjct: 1675 RRSGQAKNPVSAGGSSAPPPKAPAPPPKPETP-EKTTSEKPPEQTPETAMPEPP---APE 1730
Query: 388 SPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKP 447
PS PV + + + + P R + Q RP G+ + A+P
Sbjct: 1731 KPSLLRPVEKEKEKEKVT-RGERPLRGE---RATSGRQTRPERSLATGQPATSRLPKARP 1786
Query: 448 PSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRR 507
+ + R+ + + A G A AG PP +++ + P + E PGR L R
Sbjct: 1787 TKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPS-EDERAVPGRLLKTRA 1845
Query: 508 AFEGIR 513
E R
Sbjct: 1846 MREMYR 1851
Score = 44.3 bits (103), Expect = 3e-04
Identities = 47/173 (27%), Positives = 61/173 (35%), Gaps = 32/173 (18%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPV 402
PA P+ +PP R PP PP PP P Q AS S + ++ SP
Sbjct: 216 PAGLGPAQTPPYRPGPPDPP-----------PPPRHLPTQFNLLASSSAAAAAAEQSSPQ 264
Query: 403 PPSCQSPSPQRRSPVPPSCPAPQP-------------RPPPPPPPGERTLAERAYAKPPS 449
+ +P P PP P+ +PPPPPPP A + Y
Sbjct: 265 LYNFSGAAP---GPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH---ALQHYLSCGG 318
Query: 450 HHVKAGFQGRRSYSELAEGAAYAGASPPWL--QAEAATLPKPRAYGSELYGPG 500
+ G + + S L G GA P + A RA G E G G
Sbjct: 319 SYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGG 371
Score = 44.3 bits (103), Expect = 3e-04
Identities = 71/264 (26%), Positives = 90/264 (34%), Gaps = 28/264 (10%)
Query: 181 SNLSPPPAPAPPCTDLDLHYL--ALRGGSGLSHAGWPGSTPSVS-DLERRRLEEALEAAQ 237
S LS P+P+P + + +H L A R G+ P P + LE LE A
Sbjct: 804 SVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPA- 862
Query: 238 GEARGAQLREEQL---QAECERLQGELKQLQETRAQDLAS--NQSERDMAWVKRVGDDQV 292
A +LR E+ + L G L+ L N +D A R Q
Sbjct: 863 --APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920
Query: 293 NLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSP 352
A + LT L + T+ E+ GG P P
Sbjct: 921 TKAPRFVPLTSICFPDSLLQDEERSFFPTM--EEMFGGGAA----DDYGKAGPPEDEGDP 974
Query: 353 PARAAPPC-PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPS-PVPQRRSPVPPSCQSPS 410
A A PP PP P P CP R S A P P + + P PS +
Sbjct: 975 KAGAGPPPGPPAYDPYG------PYCPG---RASGAGPETPGLGLDPNKPPELPSTVNAE 1025
Query: 411 PQRRSPVPPSCPAPQPRPPPPPPP 434
P P AP P PPPPPPP
Sbjct: 1026 PLGLIQSGPHQAAPPPPPPPPPPP 1049
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/151 (29%), Positives = 53/151 (35%), Gaps = 20/151 (13%)
Query: 357 APPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSP 416
+PP PP P Q P P + P P PQ V SPSP
Sbjct: 763 SPPPPP---PTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKV 819
Query: 417 ----VPPSCP--APQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAA 470
+ P+ APQP PPPPPPP L A+ + SH ++ R E
Sbjct: 820 GVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR--SHGLEPAAPSPRLRPE------ 871
Query: 471 YAGASPPWLQAE--AATLPKPRAYGSELYGP 499
PP E A P P A G GP
Sbjct: 872 -ESLDPPGAMQELLGALEPLPPAPGDTGVGP 901
Score = 37.7 bits (86), Expect = 0.031
Identities = 56/228 (24%), Positives = 75/228 (32%), Gaps = 35/228 (15%)
Query: 348 PSPSPPARAAPPCPPCQSPVPQRRSPV-PPCPSPQQRRSPA--------------SPSCP 392
P P PP PP P Q R + P PSP+ R + P P
Sbjct: 833 PQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPP 892
Query: 393 SPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHV 452
+P P + P+ RSP P AP+ P + L + + P+
Sbjct: 893 APGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEE 952
Query: 453 KAGFQGRRSYSELA----EGAAYAGASPPWLQAEAATLPKPRAYGS-ELYGPGRPLSPRR 507
G Y + EG AGA PP P P AY Y PGR
Sbjct: 953 MFGGGAADDYGKAGPPEDEGDPKAGAGPP---------PGPPAYDPYGPYCPGRASGAGP 1003
Query: 508 AFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESP 555
G+ L K P +P++ + +G I+ A P P P
Sbjct: 1004 ETPGLGLDPNKPPE------LPSTVNAEPLGLIQSGPHQAAPPPPPPP 1045
Score = 34.3 bits (77), Expect = 0.35
Identities = 46/183 (25%), Positives = 57/183 (31%), Gaps = 29/183 (15%)
Query: 327 ARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSP 386
A + ++ SP S A P P PP RA P + S PP P P
Sbjct: 254 AAAAAEQSSPQLYNFSGA--APGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQ 311
Query: 387 ASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAK 446
SC P +C SP+ P+P P P T
Sbjct: 312 HYLSCGGSYPSMGHRANLAC--------SPLGGGEPSPGAGEPSKAGPSGAT-------- 355
Query: 447 PPSHHVKAGFQGRRSYSELAEGAAYAGAS---PPWLQAEAATLPKPRAYGSELYGPGRPL 503
AG GR + E A G G P +Q+ K YG+ G RP
Sbjct: 356 -------AGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGK-GGYGAAAGGATRPP 407
Query: 504 SPR 506
PR
Sbjct: 408 PPR 410
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 65.1 bits (157), Expect = 2e-10
Identities = 69/230 (30%), Positives = 86/230 (37%), Gaps = 49/230 (21%)
Query: 335 SPLSQRHSPAPQCPSPSPPARAAPP--CPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCP 392
+P S SP P PS +PP++A P PP Q P P PP P + P P
Sbjct: 675 APFSPPASP-PVSPSATPPSQAPPSLAAPPLQVP------PSPPASPPMSPSATPPPQAP 727
Query: 393 SPVPQRRSPVPPSCQ-------SPSPQRRSP---------VPPSCPA-----PQPRPPPP 431
P+ VPPS S +P R P VPPS PA P +PPP
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787
Query: 432 PPPGERTLAERAYAKPPSHHVKAGFQGRRSYS-----ELAEGAAYAGASPPWLQAEAATL 486
PP T +A PP A F G+ +S ++ A +PP L A +
Sbjct: 788 APPALATPPLQALPSPP-----ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
Query: 487 PKPRAYGSELYGPGRPLS--PRRAFEGIRLRFEKQPSEEDEWAVPTSPPS 534
P L P RP + P + G RL P P PPS
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG-------PPPPPS 885
Score = 55.5 bits (132), Expect = 1e-07
Identities = 71/287 (24%), Positives = 99/287 (34%), Gaps = 56/287 (19%)
Query: 291 QVNLALAYTELTEELG--RLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCP 348
Q +L+ A + L+ L L+ LSSL + L + S L+ P
Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
Query: 349 SPSPPAR-----AAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPAS------PSCPSPVPQ 397
+PP A PP +P+ PPCP+P ++P S P PS +
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT 589
Query: 398 RRSPVPPSCQSPSPQRRSPVPPSCP--APQPRPP----------PPPPPGERTLAERA-- 443
PP+ SP P + P PP P P P+ P PP PP L+ A
Sbjct: 590 PPPQAPPALASP-PLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP 648
Query: 444 ----------------YAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLP 487
++ PPS V+A F S ++ A +PP L A +P
Sbjct: 649 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 488 KPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPS 534
P P SP + P VP SPP+
Sbjct: 708 -----------PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Score = 55.5 bits (132), Expect = 1e-07
Identities = 64/241 (26%), Positives = 88/241 (36%), Gaps = 39/241 (16%)
Query: 332 QRHSPLSQRHSPAPQCPSPSPP----ARAAPPCPPCQSPVPQRRSPVPPCP---SPQQRR 384
Q PL+ P P SPP A P PP + P + P PP SP +
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 385 SPASPSCPSPVPQRRSPVPPSC---QSP-SPQRRSPVPPSCPAPQPRPP---------PP 431
P +P + P + P PP+ Q+P SP P+ P P PP PP
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844
Query: 432 PPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRA 491
PP TL +A +PP+ G R LA G PP ++ ++TL P
Sbjct: 845 SPPASPTL--QAPRRPPTPGPDTSVSGPRLTLALA-----PGPPPPPSRSPSSTLSGPDL 897
Query: 492 YGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPI 551
G P R ++ S + A + PP E+ A++ G P
Sbjct: 898 AGHSSSATSTP-EELRGYD----------SGPEGGAAASPPPDAELAACHPAAWSRG-PA 945
Query: 552 P 552
P
Sbjct: 946 P 946
Score = 54.7 bits (130), Expect = 2e-07
Identities = 66/245 (26%), Positives = 87/245 (35%), Gaps = 58/245 (23%)
Query: 349 SPSPPARAAPPCPP---CQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPS 405
+PSP A P PP +P+P P PP +P P +P PS PPS
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP----LPLAPPSPS--------APPS 353
Query: 406 CQS-PSPQRRSP--VPPSCPAPQPRPPP-----PPPPGERTLAERAYAKPPSHHVKAGFQ 457
Q+ PSP P PPS P + PP PP +L + PPS + Q
Sbjct: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413
Query: 458 GRRSYSELAEGAAYAGASPPWLQAEAATLP-KPRAYGSELYGPGRPLSPRRAFEGIRLRF 516
S P LQA + L PR + L P RP S
Sbjct: 414 ATTSLGS------------PTLQATHSFLTMSPRQTQASLTSPSRPASTP---------- 451
Query: 517 EKQPSEEDEWAVPTSPP-----SPEVGTIRCASFCAGFPIPESPAATAYAHAEHAQSWPS 571
P + ++P SPP SP V + P+ P + A H+ P
Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPAVSPL-------SSPLTIHPLQALSSLASHSPQAPL 504
Query: 572 INLLM 576
+L+M
Sbjct: 505 SSLIM 509
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/192 (26%), Positives = 73/192 (38%), Gaps = 39/192 (20%)
Query: 335 SPLSQRHSPAPQC-PSP--SPPARAAP--PCPPCQSPVPQRRSPVPPCPSPQQRRSPASP 389
+P S P+ Q PSP +PP++A P PP Q+P P ++ +PP P SP+
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP-PSLQT-IPPIQVPHSLTSPSLQ 401
Query: 390 SCPSPVPQRRSPVPPSCQSP---------------------SPQRRSPVPPSCP---APQ 425
+ PSP+ S SP SP R + PP P AP
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
Query: 426 PRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAA--------YAGASPP 477
P PP + A + P + H S+S A ++ + +PP
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
Query: 478 WLQAEAATLPKP 489
LQ A+L P
Sbjct: 522 SLQTPPASLTTP 533
Score = 40.4 bits (93), Expect = 0.005
Identities = 57/191 (29%), Positives = 74/191 (38%), Gaps = 24/191 (12%)
Query: 322 LLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQ 381
L + +RS +PLS SPA PS RA P P Q ++ PP +P
Sbjct: 234 LQRPASRSLSSSATPLS---SPARSGPSARGTPRA--PAHPSQPKPKGLQALRPPQVTP- 287
Query: 382 QRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPP--PPPPPGERTL 439
P + P+ P SP+ + SPS + PVPP A P P PP PP L
Sbjct: 288 ----PRKDAAPALGPLSSSPL--ATPSPSGTKARPVPPPDNAATPLPATLPPSPP----L 337
Query: 440 AERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAA--TLPK---PRAYGS 494
A PPS Q S A + P +QA + T+P P + S
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397
Query: 495 -ELYGPGRPLS 504
L P PL+
Sbjct: 398 PSLQAPPSPLA 408
Score = 39.3 bits (90), Expect = 0.011
Identities = 68/270 (25%), Positives = 104/270 (38%), Gaps = 38/270 (14%)
Query: 324 QEQARSGGQRHSPLSQRHSPAPQCPSPSPPA--RAAPPCPPC------------QSPVPQ 369
+++A++G +P ++ AP +P PP R PP P + P+ +
Sbjct: 5 RDKAKAGAAARTPAAR----APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 370 RRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPV--PPSC----QSPSPQRRSPVPPSCPA 423
R + P+ +P + S R+P PP+ ++P + SP P S P
Sbjct: 61 RAGGIGGATIPES--APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118
Query: 424 PQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEA 483
P P G++ L R A+ KA +R S L+ GA + P
Sbjct: 119 RASGTTRPGPLGQKGL--RISAEETVARGKATEAPKR--SALSAGARRDTSGPTPGTPSP 174
Query: 484 ATLPKPRAYGSE--LYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIR 541
A + RA G+E L P PR EG R K S E + T+ PSP
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPR----KSVSSASEHS--TTEPSPAARRRP 228
Query: 542 CASFCAGFPIPESPAATAYAHAEHAQSWPS 571
A P S +++A + A+S PS
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Score = 33.9 bits (76), Expect = 0.45
Identities = 39/144 (27%), Positives = 48/144 (33%), Gaps = 46/144 (31%)
Query: 336 PLSQRHSPAPQCPSP-SPPARAAPPCPPCQSPVPQ--RRSPVP----------------P 376
P+S +P PQ P + P PP PP SP Q RR P P P
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 377 CPSPQQRRSPAS----------PSCPSPVPQR------------RSPVPPSCQ----SPS 410
P P RSP+S S + P+ + PP + P+
Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938
Query: 411 PQRRSPVPPSCPAPQPRPPPPPPP 434
R P PP P P P PP
Sbjct: 939 AWSRGPAPPLAFRGAPGAPLPWPP 962
Score = 30.4 bits (67), Expect = 5.0
Identities = 50/216 (23%), Positives = 73/216 (33%), Gaps = 29/216 (13%)
Query: 309 RELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPV- 367
+ L+ G I + E A G S + +PA + P+ RA P PV
Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
Query: 368 -PQRRS-PVPPCPSPQQ---------------RRSPASPSCPSPVPQRRSPVPPSCQSPS 410
P R S P P Q+ +P + + + S P SP+
Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 411 PQRRS-------PVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPS----HHVKAGFQGR 459
RRS +P P+ +PRPP P + A PS AG +
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 460 RSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSE 495
R S +A +SP A P+ A+ S+
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 65.1 bits (157), Expect = 2e-10
Identities = 54/154 (35%), Positives = 70/154 (45%), Gaps = 18/154 (11%)
Query: 350 PSPPARAAPPC--PPCQS--PVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPV--P 403
P PP P PP + PVPQ +PVP P R+P PS P P+P++R +
Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPP-----RAPTPPSTPVPLPEKRRSILRE 606
Query: 404 PSCQSPSPQRRSPVPPSCPAPQPRPPPPPPP---GERTLAERAYAKPPSH-HVKAGFQGR 459
P+ + S R P PP P P P P PPP P R L RA PS H+K ++
Sbjct: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKI-YESV 665
Query: 460 RSYSELAEGAAYAGASPPWLQAEAATLPKPRAYG 493
+ L GA A P ++ P+PRA G
Sbjct: 666 LTPPPL--GAPEAPEPEPPPADDSPAEPEPRAVG 697
Score = 54.3 bits (129), Expect = 3e-07
Identities = 58/208 (27%), Positives = 77/208 (37%), Gaps = 41/208 (19%)
Query: 359 PCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVP 418
P PP P P SP PP P P SP P CP P P PV P P SP P
Sbjct: 402 PPPPLTPPAP---SPPPPLPPPST--SPPPPLCPPPPP----PVSP------PPLPSPPP 446
Query: 419 PSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPW 478
P PA + + PPP T + + P + +A + R+ E G SPP
Sbjct: 447 P--PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE--------GTSPPT 496
Query: 479 LQAEAAT----------LPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAV 528
AT PK + + P+ R+ I+ ++ +ED
Sbjct: 497 PTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKT--PRRFMDED---- 550
Query: 529 PTSPPSPEVGTIRCASFCAGFPIPESPA 556
P PP EV + P+P+ PA
Sbjct: 551 PPKPPKVEVSPVLRPPITTSPPVPQEPA 578
Score = 52.4 bits (124), Expect = 1e-06
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 7/99 (7%)
Query: 343 PAPQCPSPSPPARAAPP---CPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRR 399
PAP P P PP +PP CPP PV P PP P Q+ + + P R+
Sbjct: 409 PAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRK 468
Query: 400 SPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERT 438
PP +P +R+ + P+ PP P P T
Sbjct: 469 RGRPPL----TPSQRAEREAARAGPEGTSPPTPTPSTAT 503
Score = 46.2 bits (108), Expect = 9e-05
Identities = 52/189 (27%), Positives = 63/189 (33%), Gaps = 20/189 (10%)
Query: 332 QRHSPLSQRHSPA-PQCPSPSPPARAA--------PPCPPCQSP---VPQRRSPVPPCPS 379
+RHSP+ P P S PPA + P P + P V P P PS
Sbjct: 1833 ERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPS 1892
Query: 380 PQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPP-------- 431
P P P RRS P P R PP +PQ R PPP
Sbjct: 1893 SLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALT 1952
Query: 432 PPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRA 491
P GE A + PP + F+ S L+ AS + + A
Sbjct: 1953 PTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGA 2012
Query: 492 YGSELYGPG 500
GS GPG
Sbjct: 2013 MGSSHGGPG 2021
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/142 (27%), Positives = 51/142 (35%), Gaps = 37/142 (26%)
Query: 348 PSPSPPARAAPPCPPCQSPVPQR-RSPVPPC---PSPQQRRS----------------PA 387
P PP +PP P +PVP R+P PP P P++RRS P
Sbjct: 561 PVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620
Query: 388 SPSCPSPVPQRRSPVPPSCQSPSPQR-RSP----------------VPPSCPAPQPRPPP 430
P P P P P P+ S P R+P PP AP+ P
Sbjct: 621 PPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPE 680
Query: 431 PPPPGERTLAERAYAKPPSHHV 452
PPP + A ++H+
Sbjct: 681 PPPADDSPAEPEPRAVGRTNHL 702
Score = 43.9 bits (102), Expect = 4e-04
Identities = 81/361 (22%), Positives = 117/361 (32%), Gaps = 94/361 (26%)
Query: 183 LSPP-PAPAPP-------------------CTDLDL-----------HYLALRGGSGLSH 211
L+PP PAP+PP DLD + G G SH
Sbjct: 1958 LAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSH 2017
Query: 212 AGWPGSTPSVSDLERRRLE--EALEAAQGEARGAQL---REEQLQAECERLQGELKQLQE 266
G S+ S R + + +A G A A R EQL + E + +Q+
Sbjct: 2018 GGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQ 2077
Query: 267 TRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQ 326
R Q + A V D R R L I+ +L+
Sbjct: 2078 PRGQGTPPSGPGVVRAGVLGAAGD----------------RARPPEDLPSEIVDFVLKNL 2121
Query: 327 ARSGGQRHSPLSQRHSPAPQCPSPSPPARA--APPCPPCQS-----PVPQRR----SPVP 375
G P + PAP + S P++ A P P ++ P R P P
Sbjct: 2122 GGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAP 2181
Query: 376 PCPSPQQRR------------SPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVP----- 418
P P + A P P P ++ P+PP+ +P + P
Sbjct: 2182 EPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLG 2241
Query: 419 --PSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASP 476
P +P PPPPPPP L+ A PP ++ + + ++G SP
Sbjct: 2242 VLPVVGVVRPAPPPPPPPLTLVLSS-GPASPPRQAIR-----------VKRVSTFSGRSP 2289
Query: 477 P 477
P
Sbjct: 2290 P 2290
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 15/132 (11%)
Query: 324 QEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQR 383
+E AR+G + SP +P P + PP + P + + R + P S +
Sbjct: 482 REAARAGPEGTSP----PTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS 537
Query: 384 RSPASP------SCPSPVPQRRSPV--PPSCQSPS-PQRRSPVP--PSCPAPQPRPPPPP 432
R +P P P SPV PP SP PQ +PVP P P P P P P
Sbjct: 538 RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597
Query: 433 PPGERTLAERAY 444
L E +
Sbjct: 598 EKRRSILREPTF 609
Score = 39.7 bits (91), Expect = 0.008
Identities = 32/110 (29%), Positives = 43/110 (39%), Gaps = 18/110 (16%)
Query: 351 SPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPAS-----PSCPSPVPQRRSPVPPS 405
+PP AP P + P P SP P P R + S P +PV SP
Sbjct: 667 TPPPLGAPEAPEPEPP-PADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAP 725
Query: 406 CQSPSPQRRSPV------------PPSCPAPQPRPPPPPPPGERTLAERA 443
S PQ ++ + P + P PQP+ PPP P + E+A
Sbjct: 726 ALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKA 775
Score = 32.0 bits (71), Expect = 1.7
Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 14/100 (14%)
Query: 349 SPSPPARAAPPCP-PCQSPVPQR---------RSPVPPCPSPQQRRSPASPSCPSPVPQR 398
+P PP R A P P ++P +R ++ Q ++P S +C P+R
Sbjct: 159 TPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRR 218
Query: 399 RSPVPPSCQSPSPQRRSPVPPSCPA----PQPRPPPPPPP 434
PP + +R+ A P+P PPPP P
Sbjct: 219 SRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP 258
Score = 32.0 bits (71), Expect = 1.7
Identities = 40/155 (25%), Positives = 56/155 (36%), Gaps = 32/155 (20%)
Query: 393 SPVPQRRSPVPPSCQSP----------SPQRRSPVPPSCPAPQPRPPPPPPPGERTLAER 442
SP P S PP + P +P+R SP+ P +P PPP R+ +
Sbjct: 1807 SPAP---SSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFS-G 1862
Query: 443 AYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRP 502
A K P++ RR ++ G + SP L T+ P P
Sbjct: 1863 ARIKVPNYS-----PSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG----------DPDFP 1907
Query: 503 LSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEV 537
PRR+ L PS WA P SP++
Sbjct: 1908 APPRRSRRPSPLAPRPPPS---RWASPPLKTSPQL 1939
Score = 30.0 bits (66), Expect = 6.5
Identities = 21/65 (32%), Positives = 26/65 (40%), Gaps = 4/65 (6%)
Query: 340 RHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRR 399
R + APQ P +RA P P +S P PC QQ A + P P+
Sbjct: 198 RRAQAPQAPR----SRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPP 253
Query: 400 SPVPP 404
PV P
Sbjct: 254 PPVVP 258
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 63.9 bits (154), Expect = 4e-10
Identities = 39/125 (31%), Positives = 54/125 (43%), Gaps = 13/125 (10%)
Query: 337 LSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPS--- 393
L+ +SPAPQ + +PP +A P S P + PP PS + P+S + P
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTA 213
Query: 394 --PVPQRRSPVPPSCQS--------PSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERA 443
P P +P PPS + P+P +P P S AP PP P TL +
Sbjct: 214 APPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSS 273
Query: 444 YAKPP 448
+ PP
Sbjct: 274 ASAPP 278
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 16/114 (14%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPS--PQQRRSPASPSCPSPVPQRRS 400
P P + +PP+ +APP P P +P PP S P+ +P +PS +P P S
Sbjct: 193 PTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSS 252
Query: 401 PVPPSCQSP--------------SPQRRSPVPPSCPAPQPRPPPPPPPGERTLA 440
P + P +P + PP+ A P PP P P E T A
Sbjct: 253 APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAA 306
Score = 56.6 bits (135), Expect = 7e-08
Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCP------PCQSPVPQRRSPVPPCPS-----PQQRR 384
P +PAP S P AAPP P P S P + VPP PS P
Sbjct: 216 PTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSAS 275
Query: 385 SPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPP 431
+P + P P +P PPS SP+PQ + P + P P P
Sbjct: 276 APPETTAAPPTPSATTPAPPS--SPAPQETTAAPITTPNSSPTTLAP 320
>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 63.9 bits (154), Expect = 4e-10
Identities = 39/125 (31%), Positives = 54/125 (43%), Gaps = 13/125 (10%)
Query: 337 LSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPS--- 393
L+ +SPAPQ + +PP +A P S P + PP PS + P+S + P
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTA 213
Query: 394 --PVPQRRSPVPPSCQS--------PSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERA 443
P P +P PPS + P+P +P P S AP PP P TL +
Sbjct: 214 APPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSS 273
Query: 444 YAKPP 448
+ PP
Sbjct: 274 ASAPP 278
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 16/114 (14%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPS--PQQRRSPASPSCPSPVPQRRS 400
P P + +PP+ +APP P P +P PP S P+ +P +PS +P P S
Sbjct: 193 PTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSS 252
Query: 401 PVPPSCQSP--------------SPQRRSPVPPSCPAPQPRPPPPPPPGERTLA 440
P + P +P + PP+ A P PP P P E T A
Sbjct: 253 APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAA 306
Score = 56.6 bits (135), Expect = 7e-08
Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCP------PCQSPVPQRRSPVPPCPS-----PQQRR 384
P +PAP S P AAPP P P S P + VPP PS P
Sbjct: 216 PTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSAS 275
Query: 385 SPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPP 431
+P + P P +P PPS SP+PQ + P + P P P
Sbjct: 276 APPETTAAPPTPSATTPAPPS--SPAPQETTAAPITTPNSSPTTLAP 320
>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 63.9 bits (154), Expect = 4e-10
Identities = 39/125 (31%), Positives = 54/125 (43%), Gaps = 13/125 (10%)
Query: 337 LSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPS--- 393
L+ +SPAPQ + +PP +A P S P + PP PS + P+S + P
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTA 213
Query: 394 --PVPQRRSPVPPSCQS--------PSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERA 443
P P +P PPS + P+P +P P S AP PP P TL +
Sbjct: 214 APPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSS 273
Query: 444 YAKPP 448
+ PP
Sbjct: 274 ASAPP 278
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/114 (29%), Positives = 47/114 (41%), Gaps = 16/114 (14%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPS--PQQRRSPASPSCPSPVPQRRS 400
P P + +PP+ +APP P P +P PP S P+ +P +PS +P P S
Sbjct: 193 PTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSS 252
Query: 401 PVPPSCQSP--------------SPQRRSPVPPSCPAPQPRPPPPPPPGERTLA 440
P + P +P + PP+ A P PP P P E T A
Sbjct: 253 APPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAA 306
Score = 56.6 bits (135), Expect = 7e-08
Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 13/107 (12%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCP------PCQSPVPQRRSPVPPCPS-----PQQRR 384
P +PAP S P AAPP P P S P + VPP PS P
Sbjct: 216 PTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSAS 275
Query: 385 SPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPP 431
+P + P P +P PPS SP+PQ + P + P P P
Sbjct: 276 APPETTAAPPTPSATTPAPPS--SPAPQETTAAPITTPNSSPTTLAP 320
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 63.5 bits (153), Expect = 5e-10
Identities = 64/242 (26%), Positives = 83/242 (34%), Gaps = 41/242 (16%)
Query: 336 PLSQRHSPAPQCPSP-SPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSP 394
PLS +P PQ P + P APP PP P+ +P P P+ +P P P
Sbjct: 385 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
Query: 395 VPQRRSPVPPSCQ---SPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHH 451
P ++P P SPS S PPS AP + PP PP A PP
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-----------ASPP--- 490
Query: 452 VKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEG 511
++ A +PP L A L KP P P +A
Sbjct: 491 -------------MSPSATPPPQAPPPLAAPPLQLAKPPPQAP----PALATPPLQALPS 533
Query: 512 IRLRFEKQPSEEDEWAVPTSP---PSPEVGTIRCASFCAGFPIPESPAATAYAHAEHAQS 568
F Q ++P SP P P+ + A +P SP A+ A
Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPP 590
Query: 569 WP 570
P
Sbjct: 591 TP 592
Score = 57.4 bits (137), Expect = 4e-08
Identities = 61/208 (29%), Positives = 79/208 (37%), Gaps = 37/208 (17%)
Query: 335 SPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSP 394
+P S SP Q P SPP A+PP P S PP +P +P P
Sbjct: 438 APFSPPPSPPVQAPF-SPP--ASPPVSP---------SATPPSQAPPSLAAP-----PLQ 480
Query: 395 VPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQ-PRPPPPPPPGERTLAERAYAKPPSHHVK 453
VP PP S +P ++P P + P Q +PPP PP T +A PP
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP----- 535
Query: 454 AGFQGRRSYS-----ELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLS--PR 506
A F G+ +S ++ A +PP L A +P L P RP + P
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595
Query: 507 RAFEGIRLRFEKQPSEEDEWAVPTSPPS 534
+ G RL P P PPS
Sbjct: 596 TSVSGPRLTLALAPG-------PPPPPS 616
Score = 57.4 bits (137), Expect = 4e-08
Identities = 68/246 (27%), Positives = 86/246 (34%), Gaps = 47/246 (19%)
Query: 336 PLSQRHSPAPQCPSP--------------SPPARAAPPCPPCQSPVPQRRSPVPPCPSPQ 381
P+S +P PQ P P +PPA A PP SP P PS
Sbjct: 490 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549
Query: 382 QRRSPASPSCPSPVPQRRSP---VPPSCQSPSPQRRSPVPPSCPAPQ-----PR------ 427
SP + P P +P VPPS SP ++P P P P PR
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 608
Query: 428 PPPPPPPGERTLAERAYAKPPSHHVKAGF--QGRRSYSELAEGAAYAGASPP-------- 477
P PPPPP + + H A + R Y EG A ASPP
Sbjct: 609 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG--AAASPPPDAELAAC 666
Query: 478 ----WLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPP 533
W + A L A G+ L P P + + +G+ +E + E A P
Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPL--PWPPATGPGSADGLCTIYETEGPESATPAPGALDP 724
Query: 534 SPEVGT 539
P GT
Sbjct: 725 GPSPGT 730
Score = 54.3 bits (129), Expect = 3e-07
Identities = 64/240 (26%), Positives = 83/240 (34%), Gaps = 34/240 (14%)
Query: 335 SPLSQRHSPAPQCPSPSPPARAAPP--CPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCP 392
+P S SP P PS +PP++A P PP Q P P PP P + P P
Sbjct: 450 APFSPPASP-PVSPSATPPSQAPPSLAAPPLQVP------PSPPASPPMSPSATPPPQAP 502
Query: 393 SPV---------PQRRSP----VPPSCQSPSPQR----RSPVPPSCPAPQPRPPPPPPPG 435
P+ P ++P PP PSP ++P PS P PPP
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562
Query: 436 ERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSE 495
LA PPS Q R + +G A P R+ S
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622
Query: 496 LYGP---GRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIP 552
L GP G S E +R S + A + PP E+ A++ G P P
Sbjct: 623 LSGPDLAGHSSSATSTPEELR----GYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAP 677
Score = 44.7 bits (104), Expect = 3e-04
Identities = 74/274 (27%), Positives = 103/274 (37%), Gaps = 47/274 (17%)
Query: 322 LLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQ 381
L + +RS +PLS SPA PS RA P P Q ++ PP +P
Sbjct: 234 LQRPASRSLSSSATPLS---SPARSGPSARGTPRA--PAHPSQPKPKGLQALRPPQVTP- 287
Query: 382 QRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPA-------------PQPRP 428
P + P+ P SP+ + SPS +S PP+ PA P P
Sbjct: 288 ----PRKDAAPALGPLSSSPL--ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA 341
Query: 429 PPPP--PPGERTLAERAYAKPPSHHVKAGFQG-RRSYSELAEGAAYAGASPPWLQAEAAT 485
PP P PP +TL P G + ++S L A+PP A
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 486 LPKPRAYGSELYGPGRPLSP-----RRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTI 540
LP +A S P PLSP +A + + + P + PPSP V
Sbjct: 402 LPPLQAPPSPPASP--PLSPLATPSPQAPNALAVHLLQAPF--------SPPPSPPVQ-- 449
Query: 541 RCASFCAGFPIPESPAATAYAHAEHAQSWPSINL 574
A F P SP+AT + A + + P + +
Sbjct: 450 --APFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
Score = 39.3 bits (90), Expect = 0.011
Identities = 68/270 (25%), Positives = 104/270 (38%), Gaps = 38/270 (14%)
Query: 324 QEQARSGGQRHSPLSQRHSPAPQCPSPSPPA--RAAPPCPPC------------QSPVPQ 369
+++A++G +P ++ AP +P PP R PP P + P+ +
Sbjct: 5 RDKAKAGAAARTPAAR----APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 370 RRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPV--PPSC----QSPSPQRRSPVPPSCPA 423
R + P+ +P + S R+P PP+ ++P + SP P S P
Sbjct: 61 RAGGIGGATIPES--APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118
Query: 424 PQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEA 483
P P G++ L R A+ KA +R S L+ GA + P
Sbjct: 119 RASGTTRPGPLGQKGL--RISAEETVARGKATEAPKR--SALSAGARRDTSGPTPGTPSP 174
Query: 484 ATLPKPRAYGSE--LYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIR 541
A + RA G+E L P PR EG R K S E + T+ PSP
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPR----KSVSSASEHS--TTEPSPAARRRP 228
Query: 542 CASFCAGFPIPESPAATAYAHAEHAQSWPS 571
A P S +++A + A+S PS
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Score = 35.8 bits (81), Expect = 0.12
Identities = 59/235 (25%), Positives = 75/235 (31%), Gaps = 47/235 (20%)
Query: 350 PSPPARAAPPCP-----PCQSPVPQRRSPV--PPCPSPQQR---RSPASPSCPSPV---- 395
PSP AR P P + +P+ P P R R+PA PS P P
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 396 ---PQRRSPVPPSCQSPSPQRRSPVP---PSCPAPQPRPPPPPPPGERT-----LAERAY 444
PQ P + + P SP+ PS PP P + LA
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLP 339
Query: 445 AKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLS 504
PPS Q S A P LQA + LP P S L P
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL--SPLATPPPQAP 397
Query: 505 PRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAATA 559
P A ++ A P+ P SP + + P P++P A A
Sbjct: 398 PALALPPLQ-------------APPSPPASPPLSPL-------ATPSPQAPNALA 432
Score = 33.9 bits (76), Expect = 0.45
Identities = 65/293 (22%), Positives = 96/293 (32%), Gaps = 45/293 (15%)
Query: 309 RELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPV- 367
+ L+ G I + E A G S + +PA + P+ RA P PV
Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
Query: 368 -PQRRS-PVPPCPSPQQ---------------RRSPASPSCPSPVPQRRSPVPPSCQSPS 410
P R S P P Q+ +P + + + S P SP+
Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 411 PQRRS-------PVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPS----HHVKAGFQGR 459
RRS +P P+ +PRPP P + A PS AG +
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 460 RSYSELAEGAAYAGASPPWLQAEAATLPK-------PRAYGSELYGPGRPLSPRR----- 507
R S +A +SP A P+ P+ G + P + PR+
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 508 --AFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPI-PESPAA 557
L + A PT P +P ++ C P+ P SP+A
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC-QLATPLPLAPPSPSA 347
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.5 bits (153), Expect = 5e-10
Identities = 64/242 (26%), Positives = 83/242 (34%), Gaps = 41/242 (16%)
Query: 336 PLSQRHSPAPQCPSP-SPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSP 394
PLS +P PQ P + P APP PP P+ +P P P+ +P P P
Sbjct: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405
Query: 395 VPQRRSPVPPSCQ---SPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHH 451
P ++P P SPS S PPS AP + PP PP A PP
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-----------ASPP--- 451
Query: 452 VKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEG 511
++ A +PP L A L KP P P +A
Sbjct: 452 -------------MSPSATPPPQAPPPLAAPPLQLAKPPPQAP----PALATPPLQALPS 494
Query: 512 IRLRFEKQPSEEDEWAVPTSP---PSPEVGTIRCASFCAGFPIPESPAATAYAHAEHAQS 568
F Q ++P SP P P+ + A +P SP A+ A
Sbjct: 495 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPP 551
Query: 569 WP 570
P
Sbjct: 552 TP 553
Score = 57.4 bits (137), Expect = 4e-08
Identities = 68/246 (27%), Positives = 86/246 (34%), Gaps = 47/246 (19%)
Query: 336 PLSQRHSPAPQCPSP--------------SPPARAAPPCPPCQSPVPQRRSPVPPCPSPQ 381
P+S +P PQ P P +PPA A PP SP P PS
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 382 QRRSPASPSCPSPVPQRRSP---VPPSCQSPSPQRRSPVPPSCPAPQ-----PR------ 427
SP + P P +P VPPS SP ++P P P P PR
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569
Query: 428 PPPPPPPGERTLAERAYAKPPSHHVKAGF--QGRRSYSELAEGAAYAGASPP-------- 477
P PPPPP + + H A + R Y EG A ASPP
Sbjct: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG--AAASPPPDAELAAC 627
Query: 478 ----WLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPP 533
W + A L A G+ L P P + + +G+ +E + E A P
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPL--PWPPATGPGSADGLCTIYETEGPESATPAPGALDP 685
Query: 534 SPEVGT 539
P GT
Sbjct: 686 GPSPGT 691
Score = 56.6 bits (135), Expect = 7e-08
Identities = 64/232 (27%), Positives = 81/232 (34%), Gaps = 24/232 (10%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPC-----PPCQSPVPQRRSPVPPCPSPQQRRSPASPS 390
P S SP+ PS +PP+ AAPP PP P+ +P P P P P +
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA-PPLQLA 474
Query: 391 CPSPVPQRRSPVPPSCQSPSPQR----RSPVPPSCPAPQP---RPPPPPPPGERTLAERA 443
P P PP PSP ++P PS P PPP PP LA
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP---VLAAPL 531
Query: 444 YAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGP---G 500
PPS Q R + +G A P R+ S L GP G
Sbjct: 532 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591
Query: 501 RPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIP 552
S E +R S + A + PP E+ A++ G P P
Sbjct: 592 HSSSATSTPEELR----GYDSGPEGGAAASPPPDAELAACHPAAWSRG-PAP 638
Score = 54.7 bits (130), Expect = 2e-07
Identities = 69/256 (26%), Positives = 88/256 (34%), Gaps = 71/256 (27%)
Query: 337 LSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPC---------PSPQQRRSPA 387
L HS P P SP A P PP + P + P PP PSPQ + A
Sbjct: 335 LQATHSFLPS-PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393
Query: 388 -----SPSCPSPVPQRRSPV-----PPSCQSPSPQRRSP---------VPPSCPAPQP-- 426
+P P P P ++P PP S +P ++P VPPS PA P
Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453
Query: 427 ---------------------RPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYS-- 463
+PPP PP T +A PP A F G+ +S
Sbjct: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP-----ASFPGQAPFSPS 508
Query: 464 ---ELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLS--PRRAFEGIRLRFEK 518
++ A +PP L A +P L P RP + P + G RL
Sbjct: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568
Query: 519 QPSEEDEWAVPTSPPS 534
P P PPS
Sbjct: 569 APG-------PPPPPS 577
Score = 54.3 bits (129), Expect = 3e-07
Identities = 71/249 (28%), Positives = 94/249 (37%), Gaps = 32/249 (12%)
Query: 335 SPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRS-PVPPCPSPQQRRSPASPSCPS 393
+P + +PA S SP A +P PP S P ++ P PP P Q A+ S S
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ----ATTSLGS 332
Query: 394 PVPQRRS---PVPPSCQSPSPQRRSP---------VPPSCPAPQPRPP--PPPPPGERTL 439
P Q P PP +P ++P PPS PA P P P P L
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392
Query: 440 A----ERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSE 495
A + ++ PPS V+A F S ++ A +PP L A +P P S
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPPSQAPPSLAAPPLQVP-PSPPASP 450
Query: 496 LYGPGRPLSPRR--AFEGIRLRFEKQPSEEDEWAVPTSP----PSPEVGTIRCASFCAGF 549
P P+ L+ K P + A+ T P PSP A F
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP-ALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 550 PIPESPAAT 558
+P SP AT
Sbjct: 510 SLPMSPLAT 518
Score = 45.4 bits (106), Expect = 2e-04
Identities = 69/259 (26%), Positives = 86/259 (33%), Gaps = 65/259 (25%)
Query: 343 PAPQCPSPSPP--ARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSC---PSPVPQ 397
P P PSP+ +RAA P P R P PP P++ S AS PSP +
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAAR 216
Query: 398 RRSPVPPSCQSP-------------SPQR---------RSPVPPSCPAPQP----RPPPP 431
RR Q P SP R R+P PS P P+ RPP
Sbjct: 217 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 276
Query: 432 PPP-----------GERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQ 480
PP LA + + PPS Q S A P LQ
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336
Query: 481 AEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTI 540
A + LP P S L P P A ++ A P+ P SP + +
Sbjct: 337 ATHSFLPSPPL--SPLATPPPQAPPALALPPLQ-------------APPSPPASPPLSPL 381
Query: 541 RCASFCAGFPIPESPAATA 559
P P++P A A
Sbjct: 382 -------ATPSPQAPNALA 393
Score = 37.7 bits (86), Expect = 0.031
Identities = 69/259 (26%), Positives = 98/259 (37%), Gaps = 47/259 (18%)
Query: 322 LLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQ 381
L + +RS +PLS SPA PS RA P P Q ++ PP +P
Sbjct: 225 LQRPASRSLSSSATPLS---SPARSGPSARGTPRA--PAHPSQPKPKGLQALRPPQVTP- 278
Query: 382 QRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRP-PPPPPPGERTLA 440
P + P+ P SP+ +PSP P P + P+ Q P PP PP + T +
Sbjct: 279 ----PRKDAAPALGPLSSSPL----ATPSPS-APPSPSAPPSLQTLPSPPATPPSQATTS 329
Query: 441 ERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPG 500
+ +H S L A+PP A LP +A S P
Sbjct: 330 LGSPTLQATH------------SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP- 376
Query: 501 RPLSP-----RRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESP 555
PLSP +A + + + P + PPSP V A F P SP
Sbjct: 377 -PLSPLATPSPQAPNALAVHLLQAPF--------SPPPSPPVQ----APFSPPASPPVSP 423
Query: 556 AATAYAHAEHAQSWPSINL 574
+AT + A + + P + +
Sbjct: 424 SATPPSQAPPSLAAPPLQV 442
Score = 32.0 bits (71), Expect = 1.7
Identities = 64/245 (26%), Positives = 83/245 (33%), Gaps = 47/245 (19%)
Query: 329 SGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPAS 388
+G PL++R P RA P R+ PP +R PA
Sbjct: 50 AGAVGRKPLAERAGGIGGATIPESAPRAGPT-----------RTSRPPASGRGERAPPAK 98
Query: 389 PSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPP 448
+ P PV SP R S RP P G R AE A+
Sbjct: 99 NTSPGPV-------------SSPGRASGT--------TRPGPLGQKGLRISAEETVARG- 136
Query: 449 SHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSE--LYGPGRPLSPR 506
KA +R S L+ GA + P A + RA G+E L P PR
Sbjct: 137 ----KATEAPKR--SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 507 RAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAATAYAHAEHA 566
EG R K S E + T+ PSP A P S +++A + A
Sbjct: 191 PPTEGPR----KSVSSASEHS--TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244
Query: 567 QSWPS 571
+S PS
Sbjct: 245 RSGPS 249
Score = 30.8 bits (68), Expect = 3.8
Identities = 39/135 (28%), Positives = 49/135 (36%), Gaps = 42/135 (31%)
Query: 410 SPQRRSPVPPSCPAPQPRPPPPPPPGE-RTLAERAYAKPPSHHVKAGFQGRRSYSELAEG 468
+P +P PP PRPPPP P R L AG GR+ +E A G
Sbjct: 21 APGLLTPRPPG----SPRPPPPVTPAALRVLG------------AAGAVGRKPLAERAGG 64
Query: 469 AAYAGASPPWLQAEAATLPK--PRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEW 526
AT+P+ PRA GP R P + G E+ P ++
Sbjct: 65 IG------------GATIPESAPRA------GPTRTSRPPASGRG-----ERAPPAKNTS 101
Query: 527 AVPTSPPSPEVGTIR 541
P S P GT R
Sbjct: 102 PGPVSSPGRASGTTR 116
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 63.5 bits (153), Expect = 5e-10
Identities = 69/233 (29%), Positives = 86/233 (36%), Gaps = 48/233 (20%)
Query: 343 PAPQCPSP-------SPPARAAPPCPP-------------CQSPVPQRRSPVPPCPSPQQ 382
P P+ P P AR +PP PP SP S P S +
Sbjct: 911 PEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSR 970
Query: 383 RRSP---------ASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRP----- 428
+RSP +SP P P PV SP+ SP PP P P P
Sbjct: 971 QRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQ 1030
Query: 429 PPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPK 488
PPPPPP L Y PP+ V A QG + S L+ G AAT P+
Sbjct: 1031 PPPPPPAPGEL----YRLPPASAV-ATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQ 1085
Query: 489 PRAYGSELYGPGRPLSPRRA--FEGI-RLRFEKQPSEEDEWAVPTSPPSPEVG 538
P A P +P + R A G+ RL +Q S + + + PP P G
Sbjct: 1086 PIA------APPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRG 1132
Score = 35.4 bits (80), Expect = 0.16
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 410 SPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGA 469
SP++ P PP APQ RP P PG + P AGFQ +Y +A
Sbjct: 1203 SPRQLQPAPPL--APQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNY--IAIDV 1258
Query: 470 AYAGASPPWLQAEAATLPKP 489
PP Q LP+P
Sbjct: 1259 REEPGLPPQPQPPPPPLPQP 1278
Score = 35.0 bits (79), Expect = 0.20
Identities = 27/109 (24%), Positives = 34/109 (31%), Gaps = 13/109 (11%)
Query: 338 SQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQ 397
S + P P PS SP + PP P PP P R PAS + P
Sbjct: 1011 SSPYPPLPPRPSASPSSSLQPP-------------PPPPAPGELYRLPPASAVATAQGPG 1057
Query: 398 RRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAK 446
S + + PQP PP P R + + K
Sbjct: 1058 AASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVK 1106
Score = 31.2 bits (69), Expect = 2.9
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 12/81 (14%)
Query: 368 PQRRSPVPPCPSPQQRRSPASPS----CPSP--VPQRRSPVPPSCQSPS----PQRRSPV 417
P++ P PP + +P P CP P RR + R P
Sbjct: 1204 PRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPG 1263
Query: 418 PPSCPAPQPRPPPPPPPGERT 438
P P PQP PPP P PG+++
Sbjct: 1264 LP--PQPQPPPPPLPQPGDKS 1282
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 63.5 bits (153), Expect = 5e-10
Identities = 92/365 (25%), Positives = 139/365 (38%), Gaps = 73/365 (20%)
Query: 225 ERRRLEEALEAAQGEARGAQLREEQ--------LQAECERLQGEL------KQLQETRAQ 270
ERRR+EE + + E R Q +E+Q L+ E ER Q E KQL+E R
Sbjct: 404 ERRRVEEQ-QRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQS 462
Query: 271 DLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTL-------- 322
+ Q +++ A++K + Q L + + L R+ GR +
Sbjct: 463 ERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWARE 522
Query: 323 LQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQ 382
++E+ R Q++SPL++ + P P A PP P Q+P QR PV P P +
Sbjct: 523 VEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQR--PVEPQEGPHK 580
Query: 383 RRS----------PAS----PSCPSP--VPQRRSPV-----PPSCQSPSPQRRSPVPPSC 421
PAS P+ P+P P R V P+ + P P SP PP+
Sbjct: 581 SLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGP---SPNPPAW 637
Query: 422 PAPQPRPPPPPPPGERTLA-----ERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASP 476
P PP P ++A A P+ V+A + ++ + A G
Sbjct: 638 VRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPK 697
Query: 477 PWLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPS-P 535
P P P P +P P A LR E + +P S P
Sbjct: 698 P---------PGP---------PAQPPGPPNASSNPDLRRSDPGWERSDSVLPASHGHLP 739
Query: 536 EVGTI 540
+ G++
Sbjct: 740 QAGSL 744
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 63.2 bits (152), Expect = 7e-10
Identities = 64/249 (25%), Positives = 94/249 (37%), Gaps = 35/249 (14%)
Query: 335 SPLSQRHSPAPQC--PSPSPPARAAPPCPPCQSPVPQRRSPVPP-CPSPQQRRSPASPSC 391
SP R +PAP+ SPSP PP SP +P P P+P P+
Sbjct: 917 SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG 976
Query: 392 PSPVPQRRSPVPPSCQSPSPQ--------RRSPVPPSCPAPQPRPPPPPPPGERTLAERA 443
P+ + +P PP+ PSP+ + +P PP+ P P+ P P + +
Sbjct: 977 PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036
Query: 444 YAKPPSHHVKAGFQGRRSYSELAEGA----------AYAGASPPWLQA----EAATLPKP 489
A PPS +G + + L +GA G + P L+ AAT P P
Sbjct: 1037 AATPPSP------KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090
Query: 490 RAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGF 549
+ + G P+ P + P + +PPSP+ G A
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA-- 1148
Query: 550 PIPESPAAT 558
P +PAAT
Sbjct: 1149 --PTTPAAT 1155
Score = 60.8 bits (146), Expect = 3e-09
Identities = 56/183 (30%), Positives = 72/183 (39%), Gaps = 25/183 (13%)
Query: 335 SPLSQRHSPAPQCPSP-----SPPARAAPPCPPCQSPVPQRRSPVPP---CPSPQQRRSP 386
SP +PA PSP +PP + AP P P + PP P+P P
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295
Query: 387 ASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPP---PPPPPGERTLAERA 443
+ P+ P + +P PP+ PSP+ PP P P PP PP P G TL
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP--PKGAPTPPAVTPPSPKGTPTLP--- 1350
Query: 444 YAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGP-GRP 502
A PS +G + EG A+P A T P P+ G + P G P
Sbjct: 1351 -ATTPSS------KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR-GPAIPSPKGDP 1402
Query: 503 LSP 505
SP
Sbjct: 1403 TSP 1405
Score = 58.5 bits (140), Expect = 2e-08
Identities = 74/304 (24%), Positives = 110/304 (36%), Gaps = 74/304 (24%)
Query: 311 LSSLQGRILRTLLQEQARS-GGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQ 369
LSS + + L E + S G + SP + HSP P P +P A P P +P
Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATT-HSPTPPSPKGAPTPSAVTPLSPKGVTLPP 882
Query: 370 RRSPVPPC------------PSPQQ--------------RRSPASPSCPSPVPQRRSPVP 403
+ +P P P+P+Q R +PA P+ + +P P
Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942
Query: 404 PSCQSPSPQ--------RRSPVPPSCPAPQPR-------------PP---PPPPPGERTL 439
P+ PSP+ + +P PP+ P P+ PP PP P G
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002
Query: 440 AERAYAKPPSHHVKAGFQGRRSYSELAEGAAY-AGASPPWLQAEAATLPKPRAYGSELYG 498
A P +G + + +GA+ A+PP + A P P+
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK-------- 1054
Query: 499 PGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPT----SPPSPEVGTIRCASFCAGFPIPES 554
G P +P + P+ PT +PPSP+ G + G P+P
Sbjct: 1055 -GAPTTPAATLPSPK----GGPATPSLKGAPTPPAATPPSPKGGPATPSP--KGAPMP-- 1105
Query: 555 PAAT 558
PAAT
Sbjct: 1106 PAAT 1109
Score = 53.5 bits (127), Expect = 6e-07
Identities = 69/252 (27%), Positives = 94/252 (37%), Gaps = 49/252 (19%)
Query: 335 SPLSQRHSPAPQCP--SPSPPARAAPPCP------PCQSPVPQRRSPVPPCP-----SPQ 381
+P S + PA P +P PPA A PP P P P + PP P +P
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPA-ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 382 QRRSPASPSC--PSP------VPQRRSPVPPSCQSPSPQ--RRSPVPPSCPAPQPRPPPP 431
+ +P +P+ PSP P + +P P+ PSP+ +P P P PP
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 432 PPPGERTLAERA-----YAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATL 486
P G T + + A PPS K G LA + + P AAT
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPS--PKGG---------LATPSPKGAPTTP-----AATP 1248
Query: 487 PKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFC 546
P P+ + G P P ++ P + +PPSP+ G S
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP--ATSPP 1306
Query: 547 AGFPIPESPAAT 558
G P P PAAT
Sbjct: 1307 KGAPTP--PAAT 1316
Score = 52.4 bits (124), Expect = 1e-06
Identities = 47/198 (23%), Positives = 69/198 (34%), Gaps = 15/198 (7%)
Query: 323 LQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCP-PCQSPVPQRRSPVPPCPSPQ 381
L++ + + P + P P+ +PP+ PP P + +++P P P
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 382 QRRSPASPSCPSPVP----QRRSPVPPSC---QSPSPQRRSP----VPPSCPAPQPRPPP 430
PS P VP RR P+ P+ +P +P +PP+ P P+ P
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTP 1562
Query: 431 --PPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPK 488
P P A P + ++G S EL A SP A P
Sbjct: 1563 AIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622
Query: 489 PRAYGSELYGP-GRPLSP 505
G P G P SP
Sbjct: 1623 SPEKGPATPAPKGTPTSP 1640
Score = 50.4 bits (119), Expect = 5e-06
Identities = 55/240 (22%), Positives = 82/240 (34%), Gaps = 21/240 (8%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPP-CPSPQQRRSPASPSCPSP 394
P + SP +PSP PP SP +P P P+P P+ P+
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002
Query: 395 VPQRRSPVPPSCQSPSPQ---------RRSPVPPSCPAPQPRPPP---PPPPGERTLAER 442
+ +P PP+ PSP+ + + PP+ P P+ P P P G T
Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062
Query: 443 AYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQA----EAATLPKPRAYGSELYG 498
P +G + + G + P + AAT P P+ +
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122
Query: 499 PGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAAT 558
G P +P + P + +PPSP+ G A P +PAAT
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA----PTTPAAT 1178
Score = 50.1 bits (118), Expect = 6e-06
Identities = 68/283 (24%), Positives = 102/283 (36%), Gaps = 64/283 (22%)
Query: 335 SPLSQRHSPAPQ----CPSPSPPARAAPPCPPCQSPVPQRRSPVPPCP-----SP----- 380
+P + + +P+P+ P+ + P+ P PP +P + P P P SP
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645
Query: 381 ---QQRRSPASPSCP--SPVPQRRSPVP--------------PSCQS----PSPQRRSP- 416
SPAS +C + VPQ +P P+ +S +P R+ P
Sbjct: 1646 SLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQ 1705
Query: 417 -------VPPSCPAPQPR----------PPPPPPPGERTLAERAYAKPPSHHVKAGFQGR 459
PP CP P + P P P ++ ++ A K SH K
Sbjct: 1706 TKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPP 1765
Query: 460 RS-YSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRRAF----EGIRL 514
S S AA+ P A + P P P L P++ F G+ L
Sbjct: 1766 ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVL 1825
Query: 515 RFEKQ---PSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPES 554
+ P++EDE +P PP P G + S P P+S
Sbjct: 1826 ESPSKPLAPADEDE-LLPLIPPEPISGGVPFQSVLVNMPTPKS 1867
Score = 47.4 bits (111), Expect = 4e-05
Identities = 38/145 (26%), Positives = 54/145 (37%), Gaps = 26/145 (17%)
Query: 331 GQRHSPLSQRHSPAPQCPSPSPPA-----RAAPPCP------PCQSPVPQRRSPVPPCP- 378
G +P + SP +PSP A PP P P P + PP P
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 379 ----SPQQRRSPASPSC--------PSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQP 426
+P + +P +P+ P+ P + +P PP+ PS + PP AP P
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP 1289
Query: 427 R--PPPPPPPGERTLAERAYAKPPS 449
PP P G T + PP+
Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPA 1314
Score = 47.0 bits (110), Expect = 5e-05
Identities = 30/114 (26%), Positives = 45/114 (39%), Gaps = 14/114 (12%)
Query: 330 GGQRHSPLSQRHSPAPQCP-----SPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRR 384
GG SP +P P SP P P PP +P + +P P +P +
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358
Query: 385 SPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERT 438
P +PS + P PP+ +P + + P+P+ P P P G+ T
Sbjct: 1359 GPTTPS------SKEGPTPPAA---TPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
Score = 45.4 bits (106), Expect = 2e-04
Identities = 64/243 (26%), Positives = 85/243 (34%), Gaps = 42/243 (17%)
Query: 331 GQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPS 390
G +P + SP +PS P PP +P + P P P A+P
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKG---APTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 391 CP----SPVPQRRSPVPPSCQSPSPQRRSPVP-----PSCPAPQPRPP-----PPPPPGE 436
P + P + +P P+ PSP+ P P+ PA P P PPP G
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171
Query: 437 RTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSEL 496
T A PPS K G + +GA A+ P P P+ G+
Sbjct: 1172 PTTPA---ATPPS--PKGGLA-----TPSPKGAPTTPAATPPSPKGGLATPSPK--GAPT 1219
Query: 497 YGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVP-TSPPSPEVGTIRCASFCAGFPIPESP 555
P SP+ PS + P +PPSP+ G G P P P
Sbjct: 1220 TPAATPPSPKGGL--------ATPSPKGAPTTPAATPPSPKGGPATPPP--KGAPTP--P 1267
Query: 556 AAT 558
AAT
Sbjct: 1268 AAT 1270
Score = 43.9 bits (102), Expect = 4e-04
Identities = 69/284 (24%), Positives = 100/284 (35%), Gaps = 62/284 (21%)
Query: 331 GQRHSPLSQRHSPAPQCPSPSPPA-----RAAPPCP------PCQSPVPQRRSPVPPCP- 378
G +P + SP +P P A PP P P P + PP P
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Query: 379 ----SPQQRRSPASPSCPSPVPQ--------RRSPVPPSCQSPSPQ--------RRSPVP 418
+P + +P +P+ P P+ + +P P+ PSP+ + +P
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1243
Query: 419 PSCPAPQPR--PPPPPPPGERTLAERAYAKPPSHHVKAGF-----QGRRSYSELAEGAAY 471
P+ P P+ P PPP G T A PPS +K G +G + + + +
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPT---PPAATPPS--LKGGLATPPHKGAPNPAVVTPPSPK 1298
Query: 472 AG--ASPP--WLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWA 527
G SPP AAT P P+ G P P PS +
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA----------VTPPSPKGTPT 1348
Query: 528 VPTSPPSPEVGTIRCASFCAGFPIPESPAATAYAHAEHAQSWPS 571
+P + PS + G +S P PAAT A + PS
Sbjct: 1349 LPATTPSSKGGPTTPSSKEG----PTPPAATPSHKGGPAMTPPS 1388
Score = 42.4 bits (98), Expect = 0.001
Identities = 48/220 (21%), Positives = 82/220 (37%), Gaps = 18/220 (8%)
Query: 327 ARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSP 386
+ GG +P S + PA P P + A P P ++P +PV + +
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA----TPVTREGAATPSKGD 1432
Query: 387 ASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAK 446
+P +PV +++P + + S P+ PA P P PP ++ + K
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492
Query: 447 PPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRP--LS 504
P+ G A +SP + A ++ P A + L P L+
Sbjct: 1493 APATPAPMG---------APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543
Query: 505 PRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCAS 544
P+ A + PS + A+PT +P + + AS
Sbjct: 1544 PKEALIPPAMTV---PSPKKTPAIPTPKEAPATPSSKEAS 1580
Score = 33.1 bits (74), Expect = 0.77
Identities = 61/247 (24%), Positives = 87/247 (35%), Gaps = 35/247 (14%)
Query: 335 SPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRR---------- 384
S L+ S +CP+ A A + + SP+ SPQ +R
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP 817
Query: 385 --------SPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCP-APQPRPPPPPPPG 435
SP SP S +P+ S SP+ SP PPS AP P P P
Sbjct: 818 DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA-TTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 436 ERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSE 495
TL + P ++ +G + + A +S P +A P P+ +
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP---KKARATPAPKGIPAS 933
Query: 496 LYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPT----SPPSPEVGTIRCASFCAGFPI 551
G P P + + +WA PT +PPSP+ G + G P
Sbjct: 934 PSPKGAPTPPAATPPSPK---GGPATPSPKWA-PTPPAATPPSPKGGPATPSP--KGAPT 987
Query: 552 PESPAAT 558
P PAAT
Sbjct: 988 P--PAAT 992
Score = 30.8 bits (68), Expect = 3.8
Identities = 26/84 (30%), Positives = 29/84 (34%), Gaps = 10/84 (11%)
Query: 343 PAPQCPSPSPPARAAP-PCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSP 401
PA + P P A A P S P P P P SPA CP + SP
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPC---SPAPQQCPLSAANQASP 66
Query: 402 VPPSCQSPSPQRRSPVPPSCPAPQ 425
PSP + P P PQ
Sbjct: 67 F------PSPSTIASTPLEVPFPQ 84
Score = 29.6 bits (65), Expect = 8.5
Identities = 37/159 (23%), Positives = 52/159 (32%), Gaps = 17/159 (10%)
Query: 348 PSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQ 407
PSPS P PP + + P SP++ P S S + +
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE--CPTEDSGASATASSKGTLTYLAD 792
Query: 408 SPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAE 467
SPSP S +PQ + PP P V+A F S S
Sbjct: 793 SPSPLGVS------VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLS---- 842
Query: 468 GAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPR 506
+ G+ + T P P+ G+ PLSP+
Sbjct: 843 ---FQGSKDSPATTHSPTPPSPK--GAPTPSAVTPLSPK 876
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 63.2 bits (152), Expect = 7e-10
Identities = 42/113 (37%), Positives = 48/113 (42%), Gaps = 7/113 (6%)
Query: 329 SGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCP-SPQQRRSPA 387
S Q+ P S S P P PP PP PP + P P P P P +P R P
Sbjct: 387 SSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPG 446
Query: 388 SPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPR-PP----PPPPPG 435
P P+P+ P PP + P P P P P P PR PP PP PPG
Sbjct: 447 MPGLRGPLPRLLPPGPPPGRPPGPPP-GPPPGLPPGPPPRGPPPRLPPPAPPG 498
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/117 (30%), Positives = 44/117 (37%), Gaps = 10/117 (8%)
Query: 325 EQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPP----CPPCQSPVPQRRSPVPPC--P 378
E + ++H S + P ++ PP PP P P P PP P
Sbjct: 365 EAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424
Query: 379 SPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPG 435
P P P P P R P P + P P+ P PP P P PPP PPPG
Sbjct: 425 GPPTGLPPGPP--PGAPPFLRPPGMPGLRGPLPRLLPPGPP--PGRPPGPPPGPPPG 477
Score = 51.2 bits (121), Expect = 3e-06
Identities = 59/226 (26%), Positives = 81/226 (35%), Gaps = 49/226 (21%)
Query: 343 PAPQCPSPSPPAR------AAPPCPPCQSP-------VPQRRSPVPPC--PSPQQRRSPA 387
P P P P+PP R PP PP +P +P R P+P P P R P
Sbjct: 410 PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469
Query: 388 SPSCPSPV----PQRRS-------PVPPSCQSPSPQRRSP--VPPSCPAPQPRPPPPPPP 434
P P P P R P PP P P P VPP PAP PP P P
Sbjct: 470 PPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLP 529
Query: 435 GERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPK--PRAY 492
L+ P + ++ S + + + A ++ P + A + + P A
Sbjct: 530 NPGVLS------APPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTAL 583
Query: 493 GSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVG 538
G +P+R ED+ AVP + +P+ G
Sbjct: 584 RVRRENKGATAAPQR-------------KSEDDSAVPLAKAAPKSG 616
Score = 30.4 bits (67), Expect = 5.0
Identities = 17/58 (29%), Positives = 23/58 (39%)
Query: 381 QQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERT 438
Q++ S S + + PP PS + P+P P P PP PPG T
Sbjct: 371 QKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT 428
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 62.8 bits (151), Expect = 9e-10
Identities = 65/201 (32%), Positives = 83/201 (41%), Gaps = 26/201 (12%)
Query: 325 EQARSGGQRHSPLSQRHSPA------PQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCP 378
++ +G + PLS H+ P PP PP PP P P + +PP P
Sbjct: 1155 KEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPE--LPPPPPPAEPPPTDLAHLPPLP 1212
Query: 379 SPQ-QRRSPASPSCPSPVPQRRSPVPPSCQSPSP-QRRSPVP-PSCP-------APQPRP 428
P+ + R PA P SP P PVP SP+P ++ P+P P P P P
Sbjct: 1213 PPEGEARKPAKPPV-SPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVS 1271
Query: 429 PPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGA-AYAGASPPWLQAEAATLP 487
P PPPP +A A PS AG S + A A +PP L A A P
Sbjct: 1272 PKPPPPPTAPKPVKAVAGLPSG--SAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPP 1329
Query: 488 KPRAYGSELYGPGRPLSPRRA 508
P A L+ P +P PR A
Sbjct: 1330 SPGA--PALHVPAKP--PRAA 1346
Score = 56.6 bits (135), Expect = 7e-08
Identities = 56/186 (30%), Positives = 67/186 (36%), Gaps = 39/186 (20%)
Query: 329 SGGQRHSPLSQRHSPAPQCPSPSPPARAAPP----CPPCQSPVPQRRSPVPPCPSPQQRR 384
+G R P S++ P P+ P P PPA P PP P + R P P SP+
Sbjct: 1174 TGTVRRRPASEQAGP-PELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPK--- 1229
Query: 385 SPASPSCPSPVPQRR-SPVPPSCQSPSPQRRSPV--------PPSCPAPQPRPPPPPP-- 433
P PVP+ + SP P S + P P SP PP P P P P P P
Sbjct: 1230 ----PVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVK 1285
Query: 434 ---------------PGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPW 478
P A AKPP G + S A A + A PP
Sbjct: 1286 AVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAP-ALHVPAKPPR 1344
Query: 479 LQAEAA 484
A AA
Sbjct: 1345 AAAAAA 1350
Score = 47.4 bits (111), Expect = 4e-05
Identities = 43/146 (29%), Positives = 54/146 (36%), Gaps = 30/146 (20%)
Query: 331 GQRHSPLSQRHSPAPQCPSPSPPARAAP-------PCPPCQSPVPQRRSPVPPCPSPQQR 383
G+ P SP P P P + +P P P SP +R PP SP
Sbjct: 1216 GEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSP--- 1272
Query: 384 RSPASPSCPSPVPQRR---------SPVP-PSCQSPSPQRRSP-VPPSCPAPQPRPPPP- 431
+ P P+ P PV SP P P+ Q P+ + P PPS A +PP P
Sbjct: 1273 KPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPG 1332
Query: 432 --------PPPGERTLAERAYAKPPS 449
PP A A A PP+
Sbjct: 1333 APALHVPAKPPRAAAAAAAAAAAPPA 1358
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/108 (28%), Positives = 40/108 (37%), Gaps = 16/108 (14%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAP--PCPPCQSPVPQRRSPV----PPCPSPQQRRSPASP 389
P+S + P P P P P P +P P R+ P PP P SPA P
Sbjct: 1269 PVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKP 1328
Query: 390 SCPSPVPQRRSPVPPSCQSPS-PQRRSPVPPSCPAPQPRPPPPPPPGE 436
SP P+ P+ P R + + A P PP PG+
Sbjct: 1329 P---------SPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGD 1367
Score = 36.6 bits (83), Expect = 0.070
Identities = 60/250 (24%), Positives = 85/250 (34%), Gaps = 41/250 (16%)
Query: 326 QARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRS 385
+AR G HS + + P P P P + PP +P PQ + P SPQ
Sbjct: 741 EARPGRHGHSI---KRASVP--PVPGKPRQVLPPGTSHFTP-PQTPTKTRP-GSPQALGG 793
Query: 386 PASPS--------CPSPVPQRRSPVPPSCQSPSPQRRS-------PVPPSCPAPQPRPPP 430
P P+ P +P P+ P SP R PV P P P
Sbjct: 794 PHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAP 853
Query: 431 PPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPR 490
PP P A PP + G +R++S A+ + L AA P
Sbjct: 854 PPVP----TAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGP--- 906
Query: 491 AYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAV------PTSPPSPEVGTIRCAS 544
Y + GR S R +K + +AV P PP + ++
Sbjct: 907 -YATVQRRVGRSHSVRAPAGA-----DKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASA 960
Query: 545 FCAGFPIPES 554
A P+P++
Sbjct: 961 NLADEPVPDA 970
Score = 33.1 bits (74), Expect = 0.77
Identities = 20/73 (27%), Positives = 24/73 (32%)
Query: 342 SPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSP 401
SPAP P A A PP P + P P P+ P + + P
Sbjct: 1298 SPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPP 1357
Query: 402 VPPSCQSPSPQRR 414
PP SP R
Sbjct: 1358 APPEGASPGDSAR 1370
Score = 32.3 bits (72), Expect = 1.3
Identities = 22/78 (28%), Positives = 30/78 (38%), Gaps = 13/78 (16%)
Query: 380 PQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPP--------- 430
P+ + A P P P+ + + P+ ++ P P P PPP
Sbjct: 1152 PKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPPL 1211
Query: 431 PPPPGERTLAERAYAKPP 448
PPP GE R AKPP
Sbjct: 1212 PPPEGE----ARKPAKPP 1225
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 62.0 bits (149), Expect = 2e-09
Identities = 90/376 (23%), Positives = 133/376 (35%), Gaps = 62/376 (16%)
Query: 114 QHELQKNKEQEEQLGEMIQAYEKLCVEKSDLETELREMRAL--------VETHLRQICGL 165
+ E+ N +QE Q G + + V+ ET L +AL ++ L
Sbjct: 368 REEMGCNADQESQSGPGVPQTQGGEVKPKSPETALEAFKALFIRPPRKGTTADTSELEAL 427
Query: 166 EQQLRQQQGLQDAAFSNLSPPPAPAPPCTDLDLHYLALRGGS--GLSHAGWPGSTPSVSD 223
++++R ++ A F + PA P + H L + G A WP P D
Sbjct: 428 KRKMRHEKESLRAVFERSNSKPADGPSDSKSPDHSLTEQDDRTPGRLQAVWP--PPKTKD 485
Query: 224 LERRRLEEALEAAQGEARGAQL---RE-----EQLQAECE----RLQGELKQLQETRAQD 271
E + L+ + E + A L RE E LQA+ E ++GE + +
Sbjct: 486 TEEK---VGLKYTEAEYQAAILHLKREHKEEIENLQAQFELRAFHIRGEHAMITARLEET 542
Query: 272 LASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGR--ILRTLLQEQARS 329
+ + + E + W R G ++ T+ R + R L+ E +
Sbjct: 543 IENLKHELEHRW--RGGCEERKDVCISTDDDCPPKTFRNVCVQTDRETFLKPCESESKTT 600
Query: 330 GGQRHSPLSQRHSPAPQCPSPS------------------------PPARAAPPCPPCQS 365
+ P S Q P+ PP + PP PP S
Sbjct: 601 RSNQLVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPS 660
Query: 366 PVPQRRSPVPPCPSPQQRRS-PASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAP 424
+ SP PP P P P P P+P S PP P P SP PP+ P
Sbjct: 661 GLGS-LSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP 719
Query: 425 QPRPP-----PPPPPG 435
P PP PPPPPG
Sbjct: 720 PPAPPPPGLAPPPPPG 735
Score = 47.0 bits (110), Expect = 5e-05
Identities = 32/95 (33%), Positives = 40/95 (42%), Gaps = 14/95 (14%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPV 395
P+ + P P P PP PP PP S P P PP P+ +P P P+P
Sbjct: 670 PMPPVSAGPPLPPPPPPP----PPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPP-PAPP 724
Query: 396 PQRRSPVPP--------SCQSPSPQRRSPVPPSCP 422
P +P PP S S P R+ + PSCP
Sbjct: 725 PPGLAPPPPPGLFFGLGSSSSQCP-RKPAIEPSCP 758
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 62.0 bits (149), Expect = 2e-09
Identities = 60/215 (27%), Positives = 84/215 (39%), Gaps = 35/215 (16%)
Query: 324 QEQARSGGQRHSPLSQRHS---PAPQC-------PSPSPPARAAPPC------------- 360
Q QA +G + S + Q H+ P+P P+P+PP PP
Sbjct: 603 QPQAAAGSHQLS-MGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQ 661
Query: 361 -PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPV--PQRRSPVPPSCQSPS------P 411
PP SP P RSP PP Q P PS PS + P+R S Q+P+ P
Sbjct: 662 HPPSLSPKPPTRSPSPPTQHTGQ--PPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPP 719
Query: 412 QRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAY 471
+ +P+ + P Q P P P E L + ++ P + + + L
Sbjct: 720 TQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTL 779
Query: 472 AGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPR 506
AG +P Q A TLP+PR P P P+
Sbjct: 780 AGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQ 814
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 20/110 (18%)
Query: 344 APQCPSPSPPARAAPPC--------PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPV 395
AP P P PP +A P PP +P P +P Q +P PS P
Sbjct: 710 APNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQ--TPTPPSTPPLG 767
Query: 396 PQRRS-PVPPSCQSPSPQRRSP----VPPSCPAPQPR-----PPPPPPPG 435
Q S P P + +P+ P +P P P+PR PPPP PPG
Sbjct: 768 KQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPG 817
Score = 33.1 bits (74), Expect = 0.77
Identities = 39/157 (24%), Positives = 55/157 (35%), Gaps = 28/157 (17%)
Query: 332 QRHSPLSQRH-SPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPS 390
+R L+++H SPA Q PP PP P PP S + S +
Sbjct: 509 RRGGTLNRKHISPAFQ-----------PPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGT 557
Query: 391 CPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAP----------QPRPPPPPPPGERTLA 440
PS P SP P+ + PV + PAP Q +P + ++
Sbjct: 558 VPSSAGILEQGPSPGDGSP-PKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMG 616
Query: 441 ERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPP 477
+ A PS H RR+ + A G PP
Sbjct: 617 QPHNAAGPSPHTL-----RRAVKKPAPAPPKPGNPPP 648
Score = 32.0 bits (71), Expect = 1.7
Identities = 25/80 (31%), Positives = 28/80 (35%), Gaps = 4/80 (5%)
Query: 343 PAPQCPSPSPPARAAPPCP----PCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQR 398
PAPQ + P A P P P P+ R VPP P P S S + P
Sbjct: 774 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTA 833
Query: 399 RSPVPPSCQSPSPQRRSPVP 418
V S S RS P
Sbjct: 834 SKIVTDSNSRVSEPHRSIFP 853
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 62.0 bits (149), Expect = 2e-09
Identities = 60/215 (27%), Positives = 84/215 (39%), Gaps = 35/215 (16%)
Query: 324 QEQARSGGQRHSPLSQRHS---PAPQC-------PSPSPPARAAPPC------------- 360
Q QA +G + S + Q H+ P+P P+P+PP PP
Sbjct: 525 QPQAAAGSHQLS-MGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQ 583
Query: 361 -PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPV--PQRRSPVPPSCQSPS------P 411
PP SP P RSP PP Q P PS PS + P+R S Q+P+ P
Sbjct: 584 HPPSLSPKPPTRSPSPPTQHTGQ--PPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPP 641
Query: 412 QRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAY 471
+ +P+ + P Q P P P E L + ++ P + + + L
Sbjct: 642 TQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTL 701
Query: 472 AGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPR 506
AG +P Q A TLP+PR P P P+
Sbjct: 702 AGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQ 736
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 20/110 (18%)
Query: 344 APQCPSPSPPARAAPPC--------PPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPV 395
AP P P PP +A P PP +P P +P Q +P PS P
Sbjct: 632 APNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQ--TPTPPSTPPLG 689
Query: 396 PQRRS-PVPPSCQSPSPQRRSP----VPPSCPAPQPR-----PPPPPPPG 435
Q S P P + +P+ P +P P P+PR PPPP PPG
Sbjct: 690 KQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPG 739
Score = 32.0 bits (71), Expect = 1.7
Identities = 25/80 (31%), Positives = 28/80 (35%), Gaps = 4/80 (5%)
Query: 343 PAPQCPSPSPPARAAPPCP----PCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQR 398
PAPQ + P A P P P P+ R VPP P P S S + P
Sbjct: 696 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVHSAGDSSLTNTAPTA 755
Query: 399 RSPVPPSCQSPSPQRRSPVP 418
V S S RS P
Sbjct: 756 SKIVTDSNSRVSEPHRSIFP 775
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 61.6 bits (148), Expect = 2e-09
Identities = 62/241 (25%), Positives = 91/241 (37%), Gaps = 27/241 (11%)
Query: 213 GWPGSTPSVSDLERRRLE-----------EALEAAQGEARGAQLREEQLQAECE-RLQGE 260
G PG+ P D ER + + E EA+Q + +++ E E R +
Sbjct: 935 GRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAV 994
Query: 261 LKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILR 320
+ET D +S+ D N + + +E + SS
Sbjct: 995 DTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSS---- 1050
Query: 321 TLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAP-PCP-PCQSPVPQRRSPVPPCP 378
+ S + S + PS SPP R P P P P + PVP+R + P P
Sbjct: 1051 ---SSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTP 1107
Query: 379 SPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPP--PPPGE 436
P+Q SPA P+ P+ +P+ P P P P P P +P P P PPP +
Sbjct: 1108 LPEQEASPARPAGPTEESPPSAPLRP----PEPPAGPPAPAPRPDERPSSPIPLLPPPKK 1163
Query: 437 R 437
R
Sbjct: 1164 R 1164
Score = 54.3 bits (129), Expect = 3e-07
Identities = 58/206 (28%), Positives = 69/206 (33%), Gaps = 36/206 (17%)
Query: 331 GQRHSPLSQRHSPA------------PQCPSPSPPARAAPPCPPCQS------PVPQRRS 372
G H P + +PA P SP A PC S R
Sbjct: 533 GSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGG 592
Query: 373 PVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPP 432
PP P+P Q+ P P P P P S +P P P P P P PPPPP
Sbjct: 593 SPPPAPTPPQQPPPPPPPPPPPPPYLAS-LPLGYPPHQPAYLLPPRPDGPPPPEYPPPPP 651
Query: 433 PP-------GERTLAERAYAK----PPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQA 481
PP L +R A+ P S ++ R +G A A PP
Sbjct: 652 PPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLIAASAGPPGGAF 711
Query: 482 EAATLPKP----RAYG--SELYGPGR 501
A LP P AYG LY G+
Sbjct: 712 GEAFLPFPPPQEAAYGLPYALYAQGQ 737
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/107 (36%), Positives = 49/107 (45%), Gaps = 13/107 (12%)
Query: 321 TLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRR--SPVPPCP 378
T L EQ S + P + AP P P PPA PP +P P R SP+P P
Sbjct: 1106 TPLPEQEASPARPAGPTEESPPSAPLRP-PEPPAG-----PPAPAPRPDERPSSPIPLLP 1159
Query: 379 SPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQ 425
P++RR S S VP +P PP + PQ + P P S AP+
Sbjct: 1160 PPKKRRKTVSFSAIEVVP---APEPP--PATPPQAKFPGPASRKAPR 1201
Score = 32.3 bits (72), Expect = 1.3
Identities = 50/222 (22%), Positives = 69/222 (31%), Gaps = 33/222 (14%)
Query: 379 SPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERT 438
S S +S S S S S +R + +P + P P+ P P P P E
Sbjct: 1036 SSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVP 1095
Query: 439 LAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYG 498
+ ER P + + R E A P P+P A G
Sbjct: 1096 VPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRP----------PEPPA------G 1139
Query: 499 PGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAAT 558
P P +PR P E +P PP + S P PE P AT
Sbjct: 1140 PPAP-APR-------------PDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPAT 1185
Query: 559 AYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDD 600
+ P+ V IR+ PL +P++
Sbjct: 1186 P---PQAKFPGPASRKAPRGVERTIRNLPLDHASLVKSWPEE 1224
Score = 32.0 bits (71), Expect = 1.7
Identities = 27/104 (25%), Positives = 36/104 (34%), Gaps = 19/104 (18%)
Query: 350 PSPPARAAPPCPPCQSPVPQRRSPVPPC-PSPQQRRSPASPSCPSPVPQRR--------- 399
P+PPA A P P +P SP +P+ + A P + Q+R
Sbjct: 1308 PTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEE 1367
Query: 400 ---------SPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPP 434
S S RR + +P PPPPPPP
Sbjct: 1368 EGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPP 1411
Score = 30.4 bits (67), Expect = 5.0
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 10/71 (14%)
Query: 369 QRRSPVPPCPSPQQRRSPASPSCPSPV----PQRRSPVPPSCQSPSPQRRSPVPPSCPAP 424
QR + PP + ++ P +P + P S +PP P+ Q P PA
Sbjct: 377 QRHTSYPPRRATREE-PPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRP-----PAS 430
Query: 425 QPRPPPPPPPG 435
+ PP PP PG
Sbjct: 431 EAPPPEPPEPG 441
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 61.6 bits (148), Expect = 2e-09
Identities = 37/118 (31%), Positives = 51/118 (43%), Gaps = 18/118 (15%)
Query: 342 SPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRS- 400
SP P+ +P ++ +PP PP P P P PP P P +S S +P+ + S
Sbjct: 610 SPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669
Query: 401 -----------------PVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAE 441
P PP QS S + + VPP+ P P PPPPPP +A+
Sbjct: 670 ITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ 727
Score = 57.0 bits (136), Expect = 5e-08
Identities = 58/233 (24%), Positives = 77/233 (33%), Gaps = 65/233 (27%)
Query: 343 PAPQCPSPSPPARAAPPCPP--------CQSPVPQRRSPVPPCPSPQQRRSPASPSCPSP 394
PA P PSPP P PP C P P SPVP + P P+ P+
Sbjct: 820 PASYIP-PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM 878
Query: 395 VPQRRSPVP--------------------------PSCQSPSPQRRSPVPPSCPAPQPRP 428
Q PVP P P P+ PP P+P P P
Sbjct: 879 ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAP 938
Query: 429 PPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPK 488
PPPPPP + K+G G+++ + G G PP P
Sbjct: 939 PPPPPPTASPTPD-----------KSGSPGKKTSKTSSPG----GKKPP---------PT 974
Query: 489 PRAYGS--ELYGPGRPLSPRRAFEGIRLRF----EKQPSEEDEWAVPTSPPSP 535
P+ S G P R + + + +F E ++ P +PP P
Sbjct: 975 PQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/117 (34%), Positives = 50/117 (42%), Gaps = 11/117 (9%)
Query: 343 PAPQCPSPSPPARAAPPCP-PCQSPVPQRRSPVPPCPSPQ-QRRSPASPSCPSPVPQRRS 400
P P P P+P + A P PC +PQ +P PP Q Q + +P P P P +
Sbjct: 712 PPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA 771
Query: 401 PVPPSCQSPSPQRRSPVPPSCP--------APQPRPPPPPPPGERTLAERAYAKPPS 449
P+PP P P P P S A P P PP PP ++ A A PPS
Sbjct: 772 PLPPQAP-PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Score = 51.2 bits (121), Expect = 3e-06
Identities = 54/183 (29%), Positives = 75/183 (40%), Gaps = 28/183 (15%)
Query: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCP--- 392
P+ Q S PQ P P PP PP P P P Q + +P +PS P
Sbjct: 690 PVMQSQSVKPQILVP--PNGVVPPPPPPPPP------PTPGSAMAQLKPAPCAPSLPQFS 741
Query: 393 SPVP-------QRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAE-RAY 444
+P P Q + V P P P +P+PP P P+P P P +T+A
Sbjct: 742 APPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP-PKPLVTIPAPTSTKTVAPVVTQ 800
Query: 445 AKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPW--LQAEAATLPKPRAYGSELYGPGRP 502
A PP+ + + A A+Y SPP + TLPK +++ ++ P P
Sbjct: 801 AAPPTPTPPV----PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAK--PPPSP 854
Query: 503 LSP 505
LSP
Sbjct: 855 LSP 857
Score = 49.7 bits (117), Expect = 8e-06
Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 386 PASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYA 445
P + P PQ + P + PSP P PP P P P PPPPPP ++ A
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660
Query: 446 KPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEA 483
P VK R + GA + +PP +Q+++
Sbjct: 661 AP--MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQS 696
Score = 47.8 bits (112), Expect = 3e-05
Identities = 43/140 (30%), Positives = 56/140 (40%), Gaps = 22/140 (15%)
Query: 335 SPLSQRHSPAPQCPSPSPPA---------RAAPPCPPCQSPVPQRRSPVPPCPSPQQRRS 385
+PL + P P P+P + +AAPP P P +++ P P
Sbjct: 771 APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIP----- 825
Query: 386 PASPSCPSPVPQRRSPVPPS-CQSPSPQRRSPVPPSCP--APQPRPPPPPP-----PGER 437
P+ P+ P PVP P S C P P SPVP A Q PPP PP P +
Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKP 885
Query: 438 TLAERAYAKPPSHHVKAGFQ 457
A A PP+ K +Q
Sbjct: 886 VPANVAPQSPPAVKAKPKWQ 905
Score = 47.0 bits (110), Expect = 5e-05
Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 34/140 (24%)
Query: 335 SPLSQRHSPAPQCPSPSPPARAAPP---------CPPCQSPVPQRRSPVPP--CPSPQQR 383
SP + + P Q S P+ PP PP SPVP P PP P+P +
Sbjct: 894 SPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS 953
Query: 384 RSPASPSC---------PSPVPQRRSPVPPS--CQSPSPQRRS----------PVPPSCP 422
SP + P P PQR S + S + P P+R S P P
Sbjct: 954 GSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 423 APQPRPPP--PPPPGERTLA 440
+ + PPP PP PG+ L+
Sbjct: 1014 SKETLPPPAAPPKPGKLNLS 1033
Score = 44.3 bits (103), Expect = 3e-04
Identities = 40/142 (28%), Positives = 50/142 (35%), Gaps = 29/142 (20%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPC--------PSPQQRRSPASPSCP-- 392
PA P P +A P P PVP P PP P P +P P P
Sbjct: 887 PANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA 946
Query: 393 SPVPQRR-SPVPPSCQS---------PSPQRRSPVPPSCPAPQPRPPPP---------PP 433
SP P + SP + ++ P+PQR S + S A P P P P
Sbjct: 947 SPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTP 1006
Query: 434 PGERTLAERAYAKPPSHHVKAG 455
P E + PP+ K G
Sbjct: 1007 PAESGSPSKETLPPPAAPPKPG 1028
Score = 34.3 bits (77), Expect = 0.35
Identities = 39/168 (23%), Positives = 49/168 (29%), Gaps = 79/168 (47%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPC--PSPQQRRSPASPSC--------- 391
P+P P P P + P PP SPVP P PP P+P + SP +
Sbjct: 912 PSPDFPPPPPESSLVFPPPP-PSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK 970
Query: 392 PSPVPQRRSPVP-----------------------PSCQSPSPQRRSPVPPSCPA----- 423
P P PQR S + P +S SP + + PP+ P
Sbjct: 971 PPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL 1030
Query: 424 ----------------------------------PQPR-----PPPPP 432
P P PPPPP
Sbjct: 1031 NLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPP 1078
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 61.2 bits (147), Expect = 3e-09
Identities = 100/390 (25%), Positives = 145/390 (37%), Gaps = 85/390 (21%)
Query: 185 PPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEARGAQ 244
PPP P PP G P + P +D +L A + R A
Sbjct: 8 PPPLPPPPPP------------LGAPPPPPPSAPPVSTDTS------SLRRADPKGRSAL 49
Query: 245 LREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEE 304
L + Q + RL+ ++ Q+ + A + S++ + G N A T T
Sbjct: 50 LADIQ---QGTRLR-KVTQINDRSAPQIESSKG------TNKEGGGSANTRGASTPPT-- 97
Query: 305 LGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPP-- 362
L +L + +LR Q G P S+ +P+P+ P+ + PP P
Sbjct: 98 ---LGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSR--APSPRLPNKTISGPLIPPASPRL 152
Query: 363 ---------CQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRR---SPVPPSCQSPS 410
++ P+ P PP P+P P P PS P + SP P +
Sbjct: 153 GNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL 212
Query: 411 PQRRSPVPPSCPAPQPRPPPPPP--PGERTLAERAYAKP---PSH----------HVKAG 455
P PVP + P P P PPP PP P L+++A KP P H G
Sbjct: 213 PVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKA-VKPQLAPLHLPPIPPPLPLLPPCG 271
Query: 456 FQGRRSY-SELAEGAAYAGASPPWLQAEA-----ATLPKPRAYG----SELYGPGRPLSP 505
+ G ++ + A+ A A PP L A A+LP P G SE P P SP
Sbjct: 272 YPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP 331
Query: 506 RRAFEGIRLRFEKQPSEEDEWAVPTSPPSP 535
F+ P + A+P +PP+P
Sbjct: 332 ---------SFQAPPQKAGAQALP-APPAP 351
Score = 53.9 bits (128), Expect = 4e-07
Identities = 52/178 (29%), Positives = 65/178 (36%), Gaps = 36/178 (20%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQ----------------SPVPQRRSPVPPCPSPQQRRSP 386
P P P PP PP PP P+P +PPC P + P
Sbjct: 220 PCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP 279
Query: 387 ASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVP--PSCPAPQPRPPPPPPPGERTLAERAY 444
ASP+ + P P P S SP+ P P P + PPP PP ++
Sbjct: 280 ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSP------SF 333
Query: 445 AKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRP 502
PP KAG Q L A G S P+LQ + +P A G +L P P
Sbjct: 334 QAPPQ---KAGAQA------LPAPPAPPG-SQPFLQKKRH--GRPGAGGGKLNPPPAP 379
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/113 (32%), Positives = 43/113 (38%), Gaps = 34/113 (30%)
Query: 342 SPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSP 401
SPA P P PP PP S P+ P PP P +S P P+P P
Sbjct: 281 SPAQDAQEPPAPP---PPLPPYASCSPRASLPAPPLPGVN-----SSSETPPPLP----P 328
Query: 402 VPPSCQSPSPQRRS----PVPPSCPAPQP-----------------RPPPPPP 433
PS Q+P PQ+ P PP+ P QP PPP PP
Sbjct: 329 KSPSFQAP-PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPP 380
Score = 33.1 bits (74), Expect = 0.77
Identities = 18/42 (42%), Positives = 19/42 (45%), Gaps = 4/42 (9%)
Query: 401 PVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAER 442
PVPP P P P PP AP P PP PP T + R
Sbjct: 2 PVPP----PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLR 39
Score = 32.0 bits (71), Expect = 1.7
Identities = 49/192 (25%), Positives = 63/192 (32%), Gaps = 26/192 (13%)
Query: 350 PSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSP 409
P PP PP PP P P +P PP PS + S S P+ RS + Q
Sbjct: 2 PVPP----PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTS-SLRRADPKGRSALLADIQQG 56
Query: 410 SPQRRSPVPPSCPAPQ-PRPPPPPPPGERTLAERAYAKPPS--HHVKAGFQGRRSYSELA 466
+ R+ APQ G + R + PP+ GF R +
Sbjct: 57 TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116
Query: 467 EGAAYAGASPPWLQAEAATLPKPRAYGSELYGP-GRPLSPRRAFEGIRLRFEKQPSEEDE 525
G P + P PR + GP P SPR + E
Sbjct: 117 VAGGKTGQGP------GSRAPSPRLPNKTISGPLIPPASPRLG-----------NTSEAH 159
Query: 526 WAVPTSPPSPEV 537
A T+PP P V
Sbjct: 160 GAARTAPPRPNV 171
Score = 31.6 bits (70), Expect = 2.2
Identities = 13/25 (52%), Positives = 13/25 (52%)
Query: 343 PAPQCPSPSPPARAAPPCPPCQSPV 367
P P P P PP A PP PP PV
Sbjct: 7 PPPPLPPPPPPLGAPPPPPPSAPPV 31
Score = 30.4 bits (67), Expect = 5.0
Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 26/163 (15%)
Query: 329 SGGQRHSPLSQRHSPAPQCPSPSPPARA--APPCPPCQSPVPQRRSPVPPCPSPQQRRSP 386
S + PL + SP+ Q P A+A APP PP P Q++ P +
Sbjct: 318 SSSETPPPLPPK-SPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRP-------GAG 369
Query: 387 ASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAK 446
P P P RSP S S Q + P P Q R G + + +K
Sbjct: 370 GGKLNPPPAPPARSPT-TELSSKSQQATAWTPTQQPGGQLR------NGSLHIIDDFESK 422
Query: 447 PPSHHVKAGFQGRRSYSELAEGAAYAGASP------PWLQAEA 483
H V+ F Y + Y P PWLQAEA
Sbjct: 423 FTFHSVE-DFPPPDEYKPCQK--IYPSKIPRSRTPGPWLQAEA 462
>gi|197313707 5-azacytidine induced 2 isoform c [Homo sapiens]
Length = 232
Score = 61.2 bits (147), Expect = 3e-09
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Query: 1 MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 59
M+++ EDDI IL E D+ S+ GD ASHFAL+TAY DIK+RL E
Sbjct: 1 MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE 56
Query: 60 RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQK 119
+EN+ L++R++ E K LI+ F EE E + + +V + + + + +L K
Sbjct: 57 KENSLLKKRIRFLEEK--LIARFEEETSSVGREQVNKAYHAYREVCIDR--DNLKSKLDK 112
Query: 120 -NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRAL 154
NK+ E L + + + VE L TE+ + +
Sbjct: 113 MNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVM 148
>gi|197313705 5-azacytidine induced 2 isoform b [Homo sapiens]
Length = 243
Score = 61.2 bits (147), Expect = 3e-09
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 10/156 (6%)
Query: 1 MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 59
M+++ EDDI IL E D+ S+ GD ASHFAL+TAY DIK+RL E
Sbjct: 1 MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE 56
Query: 60 RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQK 119
+EN+ L++R++ E K LI+ F EE E + + +V + + + + +L K
Sbjct: 57 KENSLLKKRIRFLEEK--LIARFEEETSSVGREQVNKAYHAYREVCIDR--DNLKSKLDK 112
Query: 120 -NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRAL 154
NK+ E L + + + VE L TE+ + +
Sbjct: 113 MNKDNSESLKVLNEQLQSKEVELLQLRTEVETQQVM 148
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 61.2 bits (147), Expect = 3e-09
Identities = 102/430 (23%), Positives = 144/430 (33%), Gaps = 74/430 (17%)
Query: 185 PPPAPAPPCT-------DLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQ 237
PPP P PP T L RG L G+ R LE +
Sbjct: 9 PPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPILEKPK 68
Query: 238 GEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWV--KRVGDDQVNLA 295
G + G LQ + QG + +L+ A+D + N + + + R + ++
Sbjct: 69 GSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAPRPPVS 128
Query: 296 LAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPAR 355
A ++ R R+ R L + +R S +HS + P P PP R
Sbjct: 129 AASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTT--SSTGMKHSSS--APPPPPPGR 184
Query: 356 AA--PPCP----PCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQS- 408
A PP P ++P R P+PP P QR P P+P P + P P + ++
Sbjct: 185 RANAPPTPLPMHSSKAPAYNREKPLPPTPG--QRLHPGREGPPAPPPVKPPPSPVNIRTG 242
Query: 409 PSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAE----------------RAYAKPPSHHV 452
PS Q +P PP P P P P + E R A PP
Sbjct: 243 PSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSA 302
Query: 453 KAGFQGRRSYSELAEGAAYAGA---SPPWLQAEAATLPKP----RAYGSELYGPGRPLSP 505
R + + A PP ++ A P P R +GSE G+P P
Sbjct: 303 SPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPP 362
Query: 506 RRAFEGIRLRFEKQPSEEDEWAVPTSPP------SPEVGTIRCASFCAGF-------PIP 552
PS P PP + T+R SF F P+
Sbjct: 363 --------------PSRTPAGPPPPPPPPLRNGHRDSITTVR--SFLDDFESKYSFHPVE 406
Query: 553 ESPAATAYAH 562
+ PA Y H
Sbjct: 407 DFPAPEEYKH 416
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,287,541
Number of Sequences: 37866
Number of extensions: 2329933
Number of successful extensions: 62441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1085
Number of HSP's successfully gapped in prelim test: 2260
Number of HSP's that attempted gapping in prelim test: 17087
Number of HSP's gapped (non-prelim): 20448
length of query: 615
length of database: 18,247,518
effective HSP length: 108
effective length of query: 507
effective length of database: 14,157,990
effective search space: 7178100930
effective search space used: 7178100930
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.