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Search of human proteins with 7657443
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
(1021 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 2024 0.0
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 2006 0.0
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 2005 0.0
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 2005 0.0
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 1961 0.0
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 1961 0.0
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 1961 0.0
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 1181 0.0
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 1181 0.0
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 660 0.0
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 660 0.0
gi|190194360 protocadherin 20 [Homo sapiens] 628 e-180
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 605 e-173
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 605 e-173
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 580 e-165
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 364 e-100
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 364 e-100
gi|14589929 protocadherin 18 precursor [Homo sapiens] 358 1e-98
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 357 4e-98
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 357 4e-98
gi|94538350 protocadherin 17 precursor [Homo sapiens] 355 9e-98
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 352 1e-96
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 352 1e-96
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 351 2e-96
gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precurs... 351 2e-96
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs... 349 9e-96
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs... 349 9e-96
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 348 1e-95
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 348 1e-95
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 346 7e-95
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 2024 bits (5244), Expect = 0.0
Identities = 1021/1021 (100%), Positives = 1021/1021 (100%)
Query: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
Query: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
Query: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
Query: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
Query: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
Query: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
Query: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
Query: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
Query: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
Query: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
Query: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
Query: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
Query: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
Query: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
Query: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPVGIQVSNTT 1020
HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPVGIQVSNTT
Sbjct: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPVGIQVSNTT 1020
Query: 1021 F 1021
F
Sbjct: 1021 F 1021
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 2006 bits (5197), Expect = 0.0
Identities = 1012/1017 (99%), Positives = 1013/1017 (99%)
Query: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
Query: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
Query: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
Query: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
Query: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
Query: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
Query: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
Query: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
Query: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
Query: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
Query: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
Query: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
Query: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
Query: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
Query: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPVGIQVS 1017
HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP + S
Sbjct: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTS 1017
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 2005 bits (5195), Expect = 0.0
Identities = 1011/1011 (100%), Positives = 1011/1011 (100%)
Query: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
Query: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
Query: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
Query: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
Query: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
Query: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
Query: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
Query: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
Query: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
Query: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
Query: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
Query: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
Query: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
Query: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
Query: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 2005 bits (5195), Expect = 0.0
Identities = 1011/1011 (100%), Positives = 1011/1011 (100%)
Query: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA 60
Query: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF
Sbjct: 61 MQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIF 120
Query: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK
Sbjct: 121 RLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK 180
Query: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT
Sbjct: 181 SQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVT 240
Query: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF
Sbjct: 241 DTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF 300
Query: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI
Sbjct: 301 HLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYI 360
Query: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET
Sbjct: 361 VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLET 420
Query: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS
Sbjct: 421 AAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNS 480
Query: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI
Sbjct: 481 PGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG
Sbjct: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
Query: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT
Sbjct: 601 DNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
Query: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT
Sbjct: 661 INVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT 720
Query: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT
Sbjct: 721 RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNAT 780
Query: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP
Sbjct: 781 LINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAP 840
Query: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG
Sbjct: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
Query: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH
Sbjct: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKH 960
Query: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 961 HIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 1961 bits (5081), Expect = 0.0
Identities = 992/1009 (98%), Positives = 995/1009 (98%)
Query: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 35 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
Query: 63 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 95 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154
Query: 123 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 155 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214
Query: 183 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 215 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274
Query: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 275 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334
Query: 303 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 335 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394
Query: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 395 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454
Query: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 455 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514
Query: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 515 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574
Query: 543 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 575 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634
Query: 603 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 635 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
Query: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 695 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
Query: 723 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 755 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
Query: 783 NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 815 NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874
Query: 843 KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 875 KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934
Query: 903 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 935 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994
Query: 963 IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 995 IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1043
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 1961 bits (5081), Expect = 0.0
Identities = 992/1009 (98%), Positives = 995/1009 (98%)
Query: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 35 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
Query: 63 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 95 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 154
Query: 123 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 155 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 214
Query: 183 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 215 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 274
Query: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 275 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 334
Query: 303 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 335 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 394
Query: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 395 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 454
Query: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 455 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 514
Query: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 515 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 574
Query: 543 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 575 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 634
Query: 603 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 635 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 694
Query: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 695 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 754
Query: 723 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 755 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 814
Query: 783 NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 815 NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 874
Query: 843 KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 875 KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 934
Query: 903 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 935 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 994
Query: 963 IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 995 IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1043
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 1961 bits (5081), Expect = 0.0
Identities = 992/1009 (98%), Positives = 995/1009 (98%)
Query: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
Query: 63 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 84 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 143
Query: 123 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 144 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 203
Query: 183 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 204 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 263
Query: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 264 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 323
Query: 303 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 324 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 383
Query: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 384 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 443
Query: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 444 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 503
Query: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 504 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 563
Query: 543 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 564 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 623
Query: 603 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 624 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 683
Query: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 684 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 743
Query: 723 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 744 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803
Query: 783 NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 804 NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 863
Query: 843 KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 864 KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 923
Query: 903 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 924 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 983
Query: 963 IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 984 IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1032
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 1181 bits (3056), Expect = 0.0
Identities = 592/1012 (58%), Positives = 777/1012 (76%), Gaps = 16/1012 (1%)
Query: 8 YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
Y+ A L+AC+ S AQE YTIREE+PENV IG++ KDLN+S I + T+A + ++L
Sbjct: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Query: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 123
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
Query: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
Query: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
Query: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
Query: 304 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
Query: 364 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++
Sbjct: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
Query: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
Query: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
LT +SA D DSG NA I Y LGP+A F LD +TG+LT + DRE++++++FT+ A+
Sbjct: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
Query: 544 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
DNG PPL S V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
Query: 604 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
Query: 664 VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
+DVNDN PV I PPSN S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
Query: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
Query: 784 ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
+L+R++ E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
Query: 842 LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
KAAQ++KQ +EW +PN EN+Q KKKK+KK+ SPK+ LLNFVTIEE+K DD +
Sbjct: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
Query: 902 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++ K
Sbjct: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
Query: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTR 1010
HH+IQELPLDNTFV CD++SK SS+SSD +S S+C F+ +HTR
Sbjct: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTR 1011
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 1181 bits (3056), Expect = 0.0
Identities = 592/1012 (58%), Positives = 777/1012 (76%), Gaps = 16/1012 (1%)
Query: 8 YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
Y+ A L+AC+ S AQE YTIREE+PENV IG++ KDLN+S I + T+A + ++L
Sbjct: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Query: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 123
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
Query: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
Query: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
Query: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
Query: 304 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
Query: 364 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++
Sbjct: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
Query: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
Query: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
LT +SA D DSG NA I Y LGP+A F LD +TG+LT + DRE++++++FT+ A+
Sbjct: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
Query: 544 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
DNG PPL S V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
Query: 604 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
Query: 664 VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
+DVNDN PV I PPSN S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
Query: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
Query: 784 ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
+L+R++ E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
Query: 842 LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
KAAQ++KQ +EW +PN EN+Q KKKK+KK+ SPK+ LLNFVTIEE+K DD +
Sbjct: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
Query: 902 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++ K
Sbjct: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
Query: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTR 1010
HH+IQELPLDNTFV CD++SK SS+SSD +S S+C F+ +HTR
Sbjct: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTR 1011
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 660 bits (1703), Expect = 0.0
Identities = 401/1012 (39%), Positives = 570/1012 (56%), Gaps = 51/1012 (5%)
Query: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
LL + + A+LL A Y + EE P N LIG L D + +
Sbjct: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
Query: 63 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
Query: 117 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
Query: 177 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
Query: 234 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
Query: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
Query: 352 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
Query: 410 PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
++ L+T LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
Query: 464 PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
PVFTQS V+ PENN PG + +++A DADSG NA++ Y L P+ + F++ TG
Sbjct: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
Query: 522 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + YNF V E
Sbjct: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
Query: 582 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
Query: 642 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
+KA DGG RS+ VTINV+D NDN P +I PSN S++L+ P T G V QV A
Sbjct: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
Query: 702 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
Query: 762 LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
+ +V+L+VNE++ N TL+ L+ S + P+ + + IL VAG
Sbjct: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
Query: 822 ITVVVVIFITAVVR-CRQAPHLKAAQK-NKQNSEWATPNPENRQMIMMKKKKKKKKHSPK 879
+ V ++I + +VR CRQ Q K+ + P P + K K KK K SPK
Sbjct: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
Query: 880 NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
+ +D D G + L +L G + P + P SPDL RHY
Sbjct: 921 PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
Query: 940 KSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYS 990
+S SP P+ Q+QP++P + KH ++Q+LP NTFV + S YS
Sbjct: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 660 bits (1703), Expect = 0.0
Identities = 401/1012 (39%), Positives = 570/1012 (56%), Gaps = 51/1012 (5%)
Query: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
LL + + A+LL A Y + EE P N LIG L D + +
Sbjct: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
Query: 63 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
Query: 117 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
Query: 177 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
Query: 234 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
Query: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
Query: 352 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
Query: 410 PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
++ L+T LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
Query: 464 PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
PVFTQS V+ PENN PG + +++A DADSG NA++ Y L P+ + F++ TG
Sbjct: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
Query: 522 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + YNF V E
Sbjct: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
Query: 582 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
Query: 642 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
+KA DGG RS+ VTINV+D NDN P +I PSN S++L+ P T G V QV A
Sbjct: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
Query: 702 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
Query: 762 LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
+ +V+L+VNE++ N TL+ L+ S + P+ + + IL VAG
Sbjct: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
Query: 822 ITVVVVIFITAVVR-CRQAPHLKAAQK-NKQNSEWATPNPENRQMIMMKKKKKKKKHSPK 879
+ V ++I + +VR CRQ Q K+ + P P + K K KK K SPK
Sbjct: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
Query: 880 NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
+ +D D G + L +L G + P + P SPDL RHY
Sbjct: 921 PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
Query: 940 KSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYS 990
+S SP P+ Q+QP++P + KH ++Q+LP NTFV + S YS
Sbjct: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021
>gi|190194360 protocadherin 20 [Homo sapiens]
Length = 951
Score = 628 bits (1620), Expect = e-180
Identities = 347/820 (42%), Positives = 506/820 (61%), Gaps = 43/820 (5%)
Query: 8 YIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
++F +C+ +S A E Y++ E +P VLIG L +DL L +P + Q +L
Sbjct: 50 FLFVGPFSCLGSYSRATELLYSLNEGLPAGVLIGSLAEDLRL--LPRSAGRPDPQSQLPE 107
Query: 68 KTG---DVPL-------------IRIEEDTGEIFTTGARIDREKLC-------------- 97
+TG + PL + ++ +GE+ T+ IDRE LC
Sbjct: 108 RTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVS 167
Query: 98 -AGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINS 156
+ P D C ++V +LP E FR VK++ I DINDNAP FP + I++ +PEN+ +N+
Sbjct: 168 ISSSPSDS-CLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNT 226
Query: 157 KYTLP-AAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTY 215
+ + AVDPDVGINGVQ Y L+ +F LDV E G++ P LIV LDRE +D Y
Sbjct: 227 RLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQY 286
Query: 216 VMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD 275
V + EDGG P +A L + ++D NDN P+F +++I V++ NA VGT + + A D
Sbjct: 287 VSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVD 346
Query: 276 ADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM 335
D+G NA+I +S+S V ++ LFHL+ TG+I + + +HKL +LA+ G +
Sbjct: 347 KDLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCI 406
Query: 336 PARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGR 395
PA LV++ V P I RYI N ++ V L E P+NT IA T+ D + + +
Sbjct: 407 PAVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKY--K 464
Query: 396 VTCFTDHEIPFRLRPV--FSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLF 453
V C+ D E PFRL P ++N++LLET +DYE + Y + ++A ++ + ++
Sbjct: 465 VNCYLDGEGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIK 522
Query: 454 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEF 513
+++ D+NDNAP+F Q + ++I ENNSP LTK+ A DADS +++Y LGPDAP F
Sbjct: 523 VQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYF 582
Query: 514 SLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHN 573
SLD TG+LTV +LDRE+++KY +T+ A D G PP S TV ++++D+NDNSP F +
Sbjct: 583 SLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINK 642
Query: 574 EYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDR 633
+++F+VPEN P +G +G+I+VTD D G N V LS+++++D F ID+ G++R +S DR
Sbjct: 643 DFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDR 702
Query: 634 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGT 693
E+Q SYT +V+A DGG + SS+AK+TI ++D+NDN P+ + P SN SY LVLPST PG+
Sbjct: 703 EQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGS 762
Query: 694 VVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLV 751
V +V AVD DTGMNA + YSI+G G + F ID +TGNITL E TD GLHR+LV
Sbjct: 763 PVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLV 822
Query: 752 KANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTE 791
K +D G P+ L S V+VNLFVN++V+N + I L+RK E
Sbjct: 823 KVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPE 862
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 605 bits (1560), Expect = e-173
Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)
Query: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Query: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
Query: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
Query: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
G + +L V D E++ ++K
Sbjct: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
Query: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
Query: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
Query: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
Query: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++
Sbjct: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
Query: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG
Sbjct: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
Query: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
Query: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
Query: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
Query: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
Query: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T +
Sbjct: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
Query: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
+ + I++ VAG +TV+++I I + R CR K + ++ T
Sbjct: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
Query: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
P ++ K KK KK P L + VT+E +K + D L + +M
Sbjct: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
Query: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
Query: 975 CDSISKCSSSSSD 987
D+IS S S+
Sbjct: 1034 GDNISIGSDHCSE 1046
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 605 bits (1560), Expect = e-173
Identities = 382/1033 (36%), Positives = 570/1033 (55%), Gaps = 95/1033 (9%)
Query: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Query: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
Query: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 193
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
Query: 194 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 218
G + +L V D E++ ++K
Sbjct: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
Query: 219 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 268
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
Query: 269 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 328
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
Query: 329 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 384
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
Query: 385 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETAAYLDYESTKEYAIKLL 437
V+D+D NG VTC ++PF+L+P + + L T+ LDYE+T+E+ + ++
Sbjct: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
Query: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V A DADSG
Sbjct: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
Query: 498 NAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 557
NA+I Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
Query: 558 VSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 617
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
Query: 618 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 677
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
Query: 678 SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 737
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
Query: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPN 797
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S P+T +
Sbjct: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
Query: 798 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNKQNSEWAT 856
+ + I++ VAG +TV+++I I + R CR K + ++ T
Sbjct: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
Query: 857 PNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 916
P ++ K KK KK P L + VT+E +K + D L + +M
Sbjct: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
Query: 917 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFV-A 974
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
Query: 975 CDSISKCSSSSSD 987
D+IS S S+
Sbjct: 1034 GDNISIGSDHCSE 1046
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 580 bits (1495), Expect = e-165
Identities = 375/1014 (36%), Positives = 559/1014 (55%), Gaps = 55/1014 (5%)
Query: 28 YTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFTT 87
Y + EE P +V IG++ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Query: 88 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 143
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
Query: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 193
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
Query: 194 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 252
G + D GG RSS LQV+ T + P + +
Sbjct: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
Query: 253 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 312
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
Query: 313 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 369
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
Query: 370 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLETA 421
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L T+
Sbjct: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
Query: 422 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
Query: 482 GIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
G ++ V A DADSG NA+I Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
Query: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGD 601
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
Query: 602 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 661
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
Query: 662 NVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 721
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
Query: 722 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
Query: 782 INELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 840
I+ + +S P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
Query: 841 HLKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDG 900
K + ++ TP ++ K KK KK P L + VT+E +K + D
Sbjct: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
Query: 901 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNSK 959
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
Query: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRP 1011
H +Q+LP NTFV A D+IS S S+ ++ Y F V SV ++P
Sbjct: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQP 1024
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 364 bits (934), Expect = e-100
Identities = 234/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)
Query: 12 VLLACVVF----HSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
++L C+ F +GA++ +Y+I EE+ + +G++ KDL L+ P + ++ +
Sbjct: 17 LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71
Query: 68 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 127
G L + +G + T G RIDRE+LCA R C V IL ++ +L I
Sbjct: 72 SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125
Query: 128 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 187
+ DINDNAP F A +++ I EN A ++ LP A+DPDVG+N +Q+Y+L +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184
Query: 188 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 247
V G K P+L+++ LDREE+ + + + DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244
Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
VF E VS+PEN PVGT + + ATD D G N ++ +SF L + F LN TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303
Query: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367
I I E LD EET +++ + A DGG A A VL+ V DVNDN P + I + +PV
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360
Query: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYE 427
+E+ PL T +AL+ V D D++ NG+VTC +PF+L + + L LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417
Query: 428 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK 487
Y I + A D G PPL+ A ++V D NDN P F+Q IPENN+ G +
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477
Query: 488 VSAMDADSGPNAKINYLLGPDA------PPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
V+A+D DS NA+I Y L D S++ TG+L ++ D E+ + +
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537
Query: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL---------- 591
A D+G PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589
Query: 592 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 644
+ D D G N+ ++ +L ++ F + TG +R + + V
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 645 AEDGGRVSRSSSAKVTINVVD 665
+D G+ S++ +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670
Score = 240 bits (612), Expect = 6e-63
Identities = 196/666 (29%), Positives = 314/666 (47%), Gaps = 63/666 (9%)
Query: 201 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 254
LI +DREE + + VED R +++ VTD NDN P F+ +
Sbjct: 88 LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142
Query: 255 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 314
+V I EN G A D D+G N+ + S + F L + +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196
Query: 315 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
LDREE H L++ ASDGG L +V V V D NDN P +
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP-FRLRPVFSNQFL--LETAA 422
V + EN+P+ T++ +T TD+D NG VT ++ ++P +L N++ ++ +
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309
Query: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
LDYE T Y I++ A D G +A + I V+D NDN+P T + + + E++ G
Sbjct: 310 NLDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLG 367
Query: 483 IQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
+ ++ D DS N ++ + P E S+D L + + LDRE+ Y T+
Sbjct: 368 TVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYY-RLVIHRALDREQVSSYNITV 426
Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
A D G PPL++ + + D NDN P F+ Y Y+PEN R ++ +T DPD
Sbjct: 427 TATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSK 486
Query: 601 DNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR 653
+N+ + S+ ++ + +I+S TGV+ SFD E+ V A D G
Sbjct: 487 ENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPL 546
Query: 654 SSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNA 709
SS+ +++ V+D NDN P + P + EL S PG +V +V+AVD D+G NA
Sbjct: 547 SSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNA 606
Query: 710 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
+ Y ++ + LFA+ + TG + D ++V D GQP L + V +
Sbjct: 607 WLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLT 665
Query: 770 LFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 829
+ V +S+ ++ +L S E+P N+E +D++ Y+ + VAAV+ V++
Sbjct: 666 VAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVIVL 715
Query: 830 ITAVVR 835
+ +R
Sbjct: 716 LAHRLR 721
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 364 bits (934), Expect = e-100
Identities = 234/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)
Query: 12 VLLACVVF----HSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
++L C+ F +GA++ +Y+I EE+ + +G++ KDL L+ P + ++ +
Sbjct: 17 LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71
Query: 68 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 127
G L + +G + T G RIDRE+LCA R C V IL ++ +L I
Sbjct: 72 SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125
Query: 128 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 187
+ DINDNAP F A +++ I EN A ++ LP A+DPDVG+N +Q+Y+L +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184
Query: 188 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 247
V G K P+L+++ LDREE+ + + + DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244
Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
VF E VS+PEN PVGT + + ATD D G N ++ +SF L + F LN TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303
Query: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367
I I E LD EET +++ + A DGG A A VL+ V DVNDN P + I + +PV
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360
Query: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYE 427
+E+ PL T +AL+ V D D++ NG+VTC +PF+L + + L LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417
Query: 428 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK 487
Y I + A D G PPL+ A ++V D NDN P F+Q IPENN+ G +
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477
Query: 488 VSAMDADSGPNAKINYLLGPDA------PPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
V+A+D DS NA+I Y L D S++ TG+L ++ D E+ + +
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537
Query: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL---------- 591
A D+G PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589
Query: 592 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 644
+ D D G N+ ++ +L ++ F + TG +R + + V
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 645 AEDGGRVSRSSSAKVTINVVD 665
+D G+ S++ +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670
Score = 240 bits (612), Expect = 6e-63
Identities = 196/666 (29%), Positives = 314/666 (47%), Gaps = 63/666 (9%)
Query: 201 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 254
LI +DREE + + VED R +++ VTD NDN P F+ +
Sbjct: 88 LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142
Query: 255 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 314
+V I EN G A D D+G N+ + S + F L + +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196
Query: 315 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
LDREE H L++ ASDGG L +V V V D NDN P +
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP-FRLRPVFSNQFL--LETAA 422
V + EN+P+ T++ +T TD+D NG VT ++ ++P +L N++ ++ +
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309
Query: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
LDYE T Y I++ A D G +A + I V+D NDN+P T + + + E++ G
Sbjct: 310 NLDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLG 367
Query: 483 IQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTGMLTVVKKLDREKEDKYLFTI 540
+ ++ D DS N ++ + P E S+D L + + LDRE+ Y T+
Sbjct: 368 TVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYY-RLVIHRALDREQVSSYNITV 426
Query: 541 LAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYG 600
A D G PPL++ + + D NDN P F+ Y Y+PEN R ++ +T DPD
Sbjct: 427 TATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSK 486
Query: 601 DNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR 653
+N+ + S+ ++ + +I+S TGV+ SFD E+ V A D G
Sbjct: 487 ENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPL 546
Query: 654 SSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNA 709
SS+ +++ V+D NDN P + P + EL S PG +V +V+AVD D+G NA
Sbjct: 547 SSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNA 606
Query: 710 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 769
+ Y ++ + LFA+ + TG + D ++V D GQP L + V +
Sbjct: 607 WLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLT 665
Query: 770 LFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 829
+ V +S+ ++ +L S E+P N+E +D++ Y+ + VAAV+ V++
Sbjct: 666 VAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVIVL 715
Query: 830 ITAVVR 835
+ +R
Sbjct: 716 LAHRLR 721
>gi|14589929 protocadherin 18 precursor [Homo sapiens]
Length = 1135
Score = 358 bits (920), Expect = 1e-98
Identities = 229/662 (34%), Positives = 362/662 (54%), Gaps = 31/662 (4%)
Query: 8 YIFAVLLACVVFHSGAQEKN--YTIREEMPENVLIGDLLKDLN--LSLIPNKSLTTAMQF 63
++FA+L+ V F+ KN Y I EE +I L +D+ L +PN S ++F
Sbjct: 12 FVFALLI--VSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPS---TVRF 66
Query: 64 KLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLV 123
+ + + G+ PL+ + ED GEI + GA IDRE+LC ++ +C E +V LP E +L
Sbjct: 67 RAMQR-GNSPLLVVNEDNGEI-SIGATIDREQLCQ---KNLNCSIEFDVITLPTEHLQLF 121
Query: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
I + DINDN+P F ++I I I E++A+ ++ L +A DPDVG N + Y L + +
Sbjct: 122 HIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSL-SAND 180
Query: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
F ++V +G K +LIV +ELDRE K +Y +++ D G PQRS ++IL++S++D+N
Sbjct: 181 FFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSN 240
Query: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
DN P F++ + + EN+PVGT + L+ATD D G N KI +SFS+ VS F ++
Sbjct: 241 DNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKID 300
Query: 304 ATTGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIV 361
+ G +T+ + +D E T ++++ V A D G +PA +++ V DVNDN P I+I +
Sbjct: 301 SERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMS 360
Query: 362 NPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETA 421
+ + E P++T +AL+ V DKD+ NG + C F+L+ + N +L+ T
Sbjct: 361 PGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTN 420
Query: 422 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 481
A LD E EY++ ++A D G P L+ +++ D NDN P F +S I ENNSP
Sbjct: 421 ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSP 480
Query: 482 GIQLTKVSAMDADSGPNAKINY------LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDK 535
G +T V+A D D G N ++ Y +LG ++D G + ++ D E+ +
Sbjct: 481 GAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQ 540
Query: 536 YLFTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPV-----FTHNEYNFYVPENLPRHGTV 589
F + A+D G P L SN TV ++IID+NDN PV +N +P+ V
Sbjct: 541 ITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHV 600
Query: 590 GLITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAED 647
I D D G N+ ++ +I+ N++ F ID ++ I N+S D + V +D
Sbjct: 601 TRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQD 660
Query: 648 GG 649
G
Sbjct: 661 KG 662
Score = 233 bits (594), Expect = 7e-61
Identities = 187/628 (29%), Positives = 287/628 (45%), Gaps = 48/628 (7%)
Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVS 293
++V V D NDN P F + I + I E+A VGT + A D D+GEN+ +S S N
Sbjct: 123 IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFF 182
Query: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARA---MVLVNVTDVND 350
NI R A + + LDRE +++L + ASD G+ P R+ ++ ++++D ND
Sbjct: 183 NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGV-PQRSGSSILKISISDSND 241
Query: 351 NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-CFTDHEIPFRLR 409
N P+ + + + + L EN P+ T + + TD D NG++ F+ H P +
Sbjct: 242 NSPAFEQQSYI------IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIME 295
Query: 410 P--VFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFT 467
+ S + L +DYE TK Y I + A D G + + IKV D NDN P
Sbjct: 296 TFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEIN 355
Query: 468 QSFVTVS------IPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGM 521
+ ++ I E + + V D DSG N +I L +
Sbjct: 356 INLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNY 415
Query: 522 LTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVP 580
L + LDREK +Y T++A+D G P L++ V I D NDN P F + Y F +
Sbjct: 416 LILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVIS 475
Query: 581 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 633
EN + +T TDPD G+N VT +IL+ TID G I FD
Sbjct: 476 ENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDH 535
Query: 634 EKQESYTFYVKAEDGGRVSRS-SSAKVTINVVDVNDNKPVFIVPP-SNCSYELVLPS-TN 690
E+ TF V+A DGG + S+ V + ++D NDN PV I P N + E+ +P
Sbjct: 536 EEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAE 595
Query: 691 PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 750
G V ++ A+D D+G+NAE+ +IV GN ++F ID + +I D +
Sbjct: 596 SGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELS 655
Query: 751 VKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDY 810
V D G P L + V++ + E + T +T + VS + D
Sbjct: 656 VIIQDKGNP-QLHTKVLLKCMIFEYAESVT----------------STAMTSVSQASLDV 698
Query: 811 VKILVAAVAGTITVVVVIFITAVVRCRQ 838
I++ ++ V++VI + RC +
Sbjct: 699 SMIIIISLGAICAVLLVIMVLFATRCNR 726
Score = 180 bits (456), Expect = 7e-45
Identities = 158/567 (27%), Positives = 237/567 (41%), Gaps = 48/567 (8%)
Query: 299 LFHLNATTGLITIKEPLDREETPNHKL-LVLASDGGLMPARAMVL----VNVTDVNDNVP 353
L +N G I+I +DRE+ L + D +P + L V V D+NDN P
Sbjct: 76 LLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSP 135
Query: 354 SIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTD----HEIPFRLR 409
I + +SE+ + T+I L + D D N T I R R
Sbjct: 136 QFSRSLI------PIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTR 189
Query: 410 PVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 469
+ L LD E Y ++L A+D G P + S++L I + D NDN+P F Q
Sbjct: 190 TDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQ 249
Query: 470 FVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE----FSLDCRTGMLTVV 525
+ + EN+ G L ++A D D G N KI Y P+ F +D G LT+
Sbjct: 250 SYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLF 309
Query: 526 KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHN------EYNFYV 579
K++D E Y + A+D G + ++ + + ++D NDN P N E Y+
Sbjct: 310 KQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYI 369
Query: 580 PENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDS---QTGVIRPNISFDREKQ 636
E P V L+ V D D G N + L + F + +I N + DREK+
Sbjct: 370 FEGDPIDTFVALVRVQDKDSGLNGEIVCK-LHGHGHFKLQKTYENNYLILTNATLDREKR 428
Query: 637 ESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTN-PGTVV 695
Y+ V AED G S S+ T+ + D+NDN P F YE V+ N PG +
Sbjct: 429 SEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHF----QRSRYEFVISENNSPGAYI 484
Query: 696 FQVIAVDNDTGMNAEVRYS-----IVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 750
V A D D G N +V Y+ I+G + ID G I + D ++ +
Sbjct: 485 TTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFV 544
Query: 751 VKANDLGQPDSLFS-VVIVNLFVNESVTNATLINELVRKSTEAPVTPN--------TEIA 801
V+A D G P L S +V ++E+ +I +R +T P T I
Sbjct: 545 VEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIR 604
Query: 802 DVSSPTSDYVKILVAAVAGTITVVVVI 828
+ + ++ A VAG + +I
Sbjct: 605 AIDRDSGVNAELSCAIVAGNEENIFII 631
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 357 bits (915), Expect = 4e-98
Identities = 223/683 (32%), Positives = 354/683 (51%), Gaps = 51/683 (7%)
Query: 6 GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
G + +LL ++ +G + Y++ EE+ + +GD+ +DL L P + ++
Sbjct: 12 GLVLLGILLG-TLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR--- 65
Query: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
+ G L + +G + T G RIDRE+LC G + ++ + IL ++ ++ +
Sbjct: 66 IIPRGRTQLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGV 119
Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
+ DINDNAP F + + I I EN+A ++ LP A DPD+G N +Q+YEL + + F
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-F 178
Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
L V +G K P+L++++ LDREEK + + + DGG P R+ TA ++V V D NDN
Sbjct: 179 SLIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDN 238
Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
P F + E S+PEN +GT + ++ATD D G NA++ +SF V + A ++F L+
Sbjct: 239 APAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCN 297
Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
+G I+ LD EE+ +++ V A D ARA VL+ V DVNDN P + + + + V
Sbjct: 298 SGTISTIGELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV- 356
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
EN P T IAL+ V D+D++ NG+V CF +PF+L + N + L T LD
Sbjct: 357 -----PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLD 411
Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
E Y I + A D G PPL+ + + V D NDN PVF Q+ + IPENN G+ L
Sbjct: 412 REQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSL 471
Query: 486 TKVSAMDADSGPNAKINYLL------GPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
V+A D D NA+I Y L G S++ TG+L + D E+
Sbjct: 472 VSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVK 531
Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
++A+DNG PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 532 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAE 583
Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
+ D D G N+ ++ +L ++ F++ TG +R + +
Sbjct: 584 PGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLV 643
Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
V +D G+ S++ +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666
Score = 246 bits (629), Expect = 6e-65
Identities = 197/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)
Query: 201 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
L+ +DREE +K ++ D + ++V V D NDN P F+E+E+E+ I
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 315
ENA HA D DIG+N+ + S N L N G + +K L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200
Query: 316 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 373
DREE H L++ ASDGG + A + V V D NDN P+ P V EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254
Query: 374 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTK 430
+ L T++ ++ TD D N V ++ + + VF N + T LD+E +
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313
Query: 431 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSA 490
Y +++ A D + A + I V D NDNAP + + S+PEN+ G + ++
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371
Query: 491 MDADSGPNAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 547
D DS N ++ + + P F L+ G L LDRE+ Y T+ A D G
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429
Query: 548 PPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 607
PPL++ + +++ D NDN PVF Y+ Y+PEN PR ++ +T DPD +N+ +T
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489
Query: 608 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
S+ + + +I+S TGV+ SFD E+ V A D G SS+ ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549
Query: 661 INVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
+ V+D NDN P + P + EL S PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
+ LF++ TG + D ++V D GQP L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668
Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 835
++ +L S E+P N+E +D++ Y+ + VAAV+ V++ + +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 357 bits (915), Expect = 4e-98
Identities = 223/683 (32%), Positives = 354/683 (51%), Gaps = 51/683 (7%)
Query: 6 GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
G + +LL ++ +G + Y++ EE+ + +GD+ +DL L P + ++
Sbjct: 12 GLVLLGILLG-TLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR--- 65
Query: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
+ G L + +G + T G RIDRE+LC G + ++ + IL ++ ++ +
Sbjct: 66 IIPRGRTQLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGV 119
Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
+ DINDNAP F + + I I EN+A ++ LP A DPD+G N +Q+YEL + + F
Sbjct: 120 EVEVRDINDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-F 178
Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
L V +G K P+L++++ LDREEK + + + DGG P R+ TA ++V V D NDN
Sbjct: 179 SLIVQNGADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDN 238
Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
P F + E S+PEN +GT + ++ATD D G NA++ +SF V + A ++F L+
Sbjct: 239 APAFAQPEYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCN 297
Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
+G I+ LD EE+ +++ V A D ARA VL+ V DVNDN P + + + + V
Sbjct: 298 SGTISTIGELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV- 356
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
EN P T IAL+ V D+D++ NG+V CF +PF+L + N + L T LD
Sbjct: 357 -----PENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLD 411
Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
E Y I + A D G PPL+ + + V D NDN PVF Q+ + IPENN G+ L
Sbjct: 412 REQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSL 471
Query: 486 TKVSAMDADSGPNAKINYLL------GPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
V+A D D NA+I Y L G S++ TG+L + D E+
Sbjct: 472 VSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVK 531
Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
++A+DNG PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 532 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAE 583
Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
+ D D G N+ ++ +L ++ F++ TG +R + +
Sbjct: 584 PGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLV 643
Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
V +D G+ S++ +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666
Score = 246 bits (629), Expect = 6e-65
Identities = 197/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)
Query: 201 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
L+ +DREE +K ++ D + ++V V D NDN P F+E+E+E+ I
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 315
ENA HA D DIG+N+ + S N L N G + +K L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200
Query: 316 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 373
DREE H L++ ASDGG + A + V V D NDN P+ P V EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254
Query: 374 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTK 430
+ L T++ ++ TD D N V ++ + + VF N + T LD+E +
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313
Query: 431 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSA 490
Y +++ A D + A + I V D NDNAP + + S+PEN+ G + ++
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371
Query: 491 MDADSGPNAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 547
D DS N ++ + + P F L+ G L LDRE+ Y T+ A D G
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429
Query: 548 PPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 607
PPL++ + +++ D NDN PVF Y+ Y+PEN PR ++ +T DPD +N+ +T
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489
Query: 608 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 660
S+ + + +I+S TGV+ SFD E+ V A D G SS+ ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549
Query: 661 INVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
+ V+D NDN P + P + EL S PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
+ LF++ TG + D ++V D GQP L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668
Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 835
++ +L S E+P N+E +D++ Y+ + VAAV+ V++ + +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 355 bits (912), Expect = 9e-98
Identities = 238/675 (35%), Positives = 352/675 (52%), Gaps = 49/675 (7%)
Query: 27 NYTIREEMPENVLIGDLLKDLNLSL-IPNKSLTTAMQFKL----VYKTGDVPLIRIEEDT 81
NY++ EE +IG++ +D L +P + K V + L+ ++ D+
Sbjct: 22 NYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVDADS 81
Query: 82 GEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPA 141
G ++T RIDRE LC + C +EV EI ++K+ I+DINDNAP F +
Sbjct: 82 GLLYTK-QRIDRESLCR---HNAKCQLSLEVFANDKEIC-MIKVE--IQDINDNAPSFSS 134
Query: 142 TVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN-IFGLDVIETPEGDKMPQ 200
I + I EN+A +++ L +A DPD G NG++ Y L + + +FGLDV +G K P+
Sbjct: 135 DQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPE 194
Query: 201 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 260
L++QK LDRE+++ + + + DGG P RS+T + V V D+NDN PVF+ V +PE
Sbjct: 195 LVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPE 254
Query: 261 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 320
NAP+GT V L+ATDAD G N ++ +SFS+ V + R LF ++ TGLI +K LD EE
Sbjct: 255 NAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEEN 314
Query: 321 PNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 378
++ V A D G +PA V V + D NDN PSI + LSE P T
Sbjct: 315 GMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG-----ALSEAAPPGT 369
Query: 379 KIALITVTDKDADHNGRVTCFT---------------DHEIPFRLRPVFSNQFLLETAAY 423
IAL+ VTD+D+ NG++ C +PF+L + N + + T
Sbjct: 370 VIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRP 429
Query: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
LD E+ EY + ++A D G PPLN + IK+ DENDN P FT+ + + ENN PG
Sbjct: 430 LDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGE 489
Query: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSL------DCRTGMLTVVKKLDREKEDKYL 537
L V A D D G N ++Y + P + S+ + G + ++ + E+ +
Sbjct: 490 YLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFE 549
Query: 538 FTILAKDNGVPP-LTSNVTVFVSIIDQNDNSPVFT-----HNEYNFYVPENLPRHGTVGL 591
F +LAKD+G P L SN TV V+++D NDN+PV ++ VP N V
Sbjct: 550 FKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVST 609
Query: 592 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 649
+ D D+G++ +T I+D NDD F ID +G IR F + VK D G
Sbjct: 610 VRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHG 669
Query: 650 RVSRSSSAKVTINVV 664
+ + S+ AK+ I V
Sbjct: 670 KPTLSAVAKLIIRSV 684
Score = 248 bits (634), Expect = 2e-65
Identities = 233/816 (28%), Positives = 357/816 (43%), Gaps = 101/816 (12%)
Query: 136 APLFPATVINISIPENSAINS-----------KYTLPAAVDPDVGINGVQNYELIKSQNI 184
AP +N S+PE + + LP A G + +Y ++++
Sbjct: 13 APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72
Query: 185 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 244
LDV + G L ++ +DRE + K ++ F +++V + D ND
Sbjct: 73 HLLDV-DADSG----LLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDIND 127
Query: 245 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 304
N P F +IE+ I ENA GT A D D GEN + L++ LF L+
Sbjct: 128 NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTY----LLTRDDHGLFGLDV 183
Query: 305 TTG-------LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSI 355
+ + I++ LDRE+ +H L++ A DGG P A V +NV D NDN P
Sbjct: 184 KSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVF 243
Query: 356 DI-RYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS- 413
+ Y+V L EN PL T + + TD D NG V +P R+R +FS
Sbjct: 244 EAPSYLVE-------LPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSI 296
Query: 414 --NQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFV 471
L+ LDYE I + A D G P+ + +K+ D NDNAP FV
Sbjct: 297 DPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSI--GFV 354
Query: 472 TV---SIPENNSPGIQLTKVSAMDADSGPNAKINY-------------LLGPDAPPEFSL 515
+V ++ E PG + V D DSG N ++ L GP F L
Sbjct: 355 SVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL 414
Query: 516 DCR-TGMLTVV--KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 572
+ TVV + LDRE +D+Y TI+A+D G PPL S + + I+D+NDN P FT
Sbjct: 415 EENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTK 474
Query: 573 NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD-------FTIDSQTGVI 625
Y V EN +G + DPD G N V+ SIL + +++ G I
Sbjct: 475 GLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAI 534
Query: 626 RPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFIVPP-SNCSYE 683
SF+ E+ +++ F V A+D G + S+A V + V+DVNDN PV ++P N + E
Sbjct: 535 YALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAE 594
Query: 684 LVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKC--D 740
L +P + G +V V A+D+D G + + Y IV GN LF ID +G I + D
Sbjct: 595 LQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWED 654
Query: 741 VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEI 800
VT + ++VK D G+P + + +L+ +S +
Sbjct: 655 VTP--VVELVVKVTDHGKP------------------TLSAVAKLIIRSVSGSLPEGVPR 694
Query: 801 ADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNKQNSEWATPNPE 860
+ D L+ ++ +++ IT V+C+ ++NK+ + E
Sbjct: 695 VNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCK--------RENKEIRTYNCRIAE 746
Query: 861 NRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDV 896
+ K KKKK + +++L +EE A +V
Sbjct: 747 YSHPQLGGGKGKKKKINKNDIMLVQSEVEERNAMNV 782
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 352 bits (903), Expect = 1e-96
Identities = 235/669 (35%), Positives = 358/669 (53%), Gaps = 36/669 (5%)
Query: 12 VLLACVVFHSGAQEKN--YTIREEMPENVLIGDLLKDLN---LSLIPNKSLTTAMQFKLV 66
+LL +++ A N Y++ EE +I ++ KD +L P + A F++V
Sbjct: 9 LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQ----ASAFRVV 64
Query: 67 YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 126
+ L+ I +G + T +IDR+ LC P+ C +EV EI ++K+
Sbjct: 65 SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118
Query: 127 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 186
I+D+NDNAP FPA I + I E ++ ++ L +A DPD G GVQ YEL ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175
Query: 187 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 246
L++ +G + +L+V+K LDRE + Y ++ DGG P R T L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235
Query: 247 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 306
PVF E+ VS+PEN+P T V +L+A+D D G N ++ +SF V++ R LF ++ +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295
Query: 307 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 364
GL+T+ LD EE ++L V A D G +PA V V+V D NDN P I+ +++
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352
Query: 365 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYL 424
++ V +SE+ P IAL+ V+D+D+ NGRV C +PFRL+ S +L L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTIL-VDGRL 411
Query: 425 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
D E +Y + + A D G P L + + + DENDN P F++ + V + ENN+PG
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471
Query: 485 LTKVSAMDADSGPNAKINYLLGP----DAP--PEFSLDCRTGMLTVVKKLDREKEDKYLF 538
L VSA D D G N ++Y + P D P S++ +G + ++ + E+ + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531
Query: 539 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYNFYVPENLPRHGTVGLIT 593
+LAKD G+P L SN TV V I+D NDN+PV T + Y+P N V ++
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591
Query: 594 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 652
D D G+N VT + + + F ID G +R +F + SY V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651
Query: 653 RSSSAKVTI 661
S+SA V I
Sbjct: 652 LSASALVLI 660
Score = 215 bits (547), Expect = 2e-55
Identities = 200/742 (26%), Positives = 315/742 (42%), Gaps = 74/742 (9%)
Query: 201 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 260
L+ ++++DR+ K + +++V + D NDN P F +IE+ I E
Sbjct: 81 LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140
Query: 261 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 313
A GT + A D D G + + LF L T + +++
Sbjct: 141 AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194
Query: 314 PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 371
LDRE ++ + A DGG P V + VTD NDN P + + V +
Sbjct: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248
Query: 372 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYES 428
EN P NT + + +D D NG+V + R R +F + L+ LDYE
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308
Query: 429 TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 485
Y + + A D G + + + V D NDN PV V V + E+ PG +
Sbjct: 309 GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368
Query: 486 TKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDN 545
V D DSG N ++ L + P + V +LDRE+ D+Y TI A+D
Sbjct: 369 ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428
Query: 546 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV 605
GVP L S + V I D+NDN P F+ Y V EN + ++ DPD G N +V
Sbjct: 429 GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488
Query: 606 TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 658
+ I+ +I+ +G I SF+ E+ +++ F V A+DGG S S+A
Sbjct: 489 SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548
Query: 659 VTINVVDVNDNKPVFIVPP-SNCSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
V + ++DVNDN PV PP N + E+ +P ++ G +V V A D D G N V Y +
Sbjct: 549 VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608
Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
G+ R F IDQ G + + + ++V A+D G+ SL + +V ++++ ++
Sbjct: 609 EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666
Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 836
A S + + I + A+ ++ V I ++C
Sbjct: 667 D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703
Query: 837 RQAPHLKAAQKNKQNSEWATPNPENRQMIM--MKKKKKKKKHSPKNLLLNFVTIEETKAD 894
+ + N E T N + KK KKKK S ++ L +EET
Sbjct: 704 K-----------RDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKM 752
Query: 895 DVDSDGNRVTLDLPIDLEEQTM 916
+V S + + D +QT+
Sbjct: 753 NVVSCSSLTSSLNYFDYHQQTL 774
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 352 bits (903), Expect = 1e-96
Identities = 235/669 (35%), Positives = 358/669 (53%), Gaps = 36/669 (5%)
Query: 12 VLLACVVFHSGAQEKN--YTIREEMPENVLIGDLLKDLN---LSLIPNKSLTTAMQFKLV 66
+LL +++ A N Y++ EE +I ++ KD +L P + A F++V
Sbjct: 9 LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQ----ASAFRVV 64
Query: 67 YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 126
+ L+ I +G + T +IDR+ LC P+ C +EV EI ++K+
Sbjct: 65 SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118
Query: 127 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 186
I+D+NDNAP FPA I + I E ++ ++ L +A DPD G GVQ YEL ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175
Query: 187 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 246
L++ +G + +L+V+K LDRE + Y ++ DGG P R T L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235
Query: 247 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 306
PVF E+ VS+PEN+P T V +L+A+D D G N ++ +SF V++ R LF ++ +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295
Query: 307 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 364
GL+T+ LD EE ++L V A D G +PA V V+V D NDN P I+ +++
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352
Query: 365 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYL 424
++ V +SE+ P IAL+ V+D+D+ NGRV C +PFRL+ S +L L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTIL-VDGRL 411
Query: 425 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 484
D E +Y + + A D G P L + + + DENDN P F++ + V + ENN+PG
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471
Query: 485 LTKVSAMDADSGPNAKINYLLGP----DAP--PEFSLDCRTGMLTVVKKLDREKEDKYLF 538
L VSA D D G N ++Y + P D P S++ +G + ++ + E+ + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531
Query: 539 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYNFYVPENLPRHGTVGLIT 593
+LAKD G+P L SN TV V I+D NDN+PV T + Y+P N V ++
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591
Query: 594 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 652
D D G+N VT + + + F ID G +R +F + SY V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651
Query: 653 RSSSAKVTI 661
S+SA V I
Sbjct: 652 LSASALVLI 660
Score = 215 bits (547), Expect = 2e-55
Identities = 200/742 (26%), Positives = 315/742 (42%), Gaps = 74/742 (9%)
Query: 201 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 260
L+ ++++DR+ K + +++V + D NDN P F +IE+ I E
Sbjct: 81 LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140
Query: 261 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 313
A GT + A D D G + + LF L T + +++
Sbjct: 141 AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194
Query: 314 PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 371
LDRE ++ + A DGG P V + VTD NDN P + + V +
Sbjct: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248
Query: 372 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYES 428
EN P NT + + +D D NG+V + R R +F + L+ LDYE
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308
Query: 429 TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 485
Y + + A D G + + + V D NDN PV V V + E+ PG +
Sbjct: 309 GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368
Query: 486 TKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDN 545
V D DSG N ++ L + P + V +LDRE+ D+Y TI A+D
Sbjct: 369 ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428
Query: 546 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAV 605
GVP L S + V I D+NDN P F+ Y V EN + ++ DPD G N +V
Sbjct: 429 GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488
Query: 606 TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 658
+ I+ +I+ +G I SF+ E+ +++ F V A+DGG S S+A
Sbjct: 489 SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548
Query: 659 VTINVVDVNDNKPVFIVPP-SNCSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 716
V + ++DVNDN PV PP N + E+ +P ++ G +V V A D D G N V Y +
Sbjct: 549 VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608
Query: 717 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
G+ R F IDQ G + + + ++V A+D G+ SL + +V ++++ ++
Sbjct: 609 EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666
Query: 777 TNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 836
A S + + I + A+ ++ V I ++C
Sbjct: 667 D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703
Query: 837 RQAPHLKAAQKNKQNSEWATPNPENRQMIM--MKKKKKKKKHSPKNLLLNFVTIEETKAD 894
+ + N E T N + KK KKKK S ++ L +EET
Sbjct: 704 K-----------RDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKM 752
Query: 895 DVDSDGNRVTLDLPIDLEEQTM 916
+V S + + D +QT+
Sbjct: 753 NVVSCSSLTSSLNYFDYHQQTL 774
>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 351 bits (900), Expect = 2e-96
Identities = 230/683 (33%), Positives = 354/683 (51%), Gaps = 51/683 (7%)
Query: 6 GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
G ++ ++LL + + A Y++ EE + +GD+ KDL L P + ++
Sbjct: 12 GFFLLSILLG-TPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR--- 65
Query: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
+ G L + + +G + T G RIDRE++CA R C V IL ++ L I
Sbjct: 66 IISRGRTQLFALNQRSGSLVTAG-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPI 119
Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
I DINDN P F IN+ I EN+A ++ L A DPDVG N +Q+Y+L +++ F
Sbjct: 120 DVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-F 178
Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
L V + K P+L++++ LDREE+ + + + DGG P RSSTA +QV+V D ND+
Sbjct: 179 SLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDH 238
Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
PVF + +V++PEN PVGT + +HA D D G N ++ +SF + + + +FHLN+
Sbjct: 239 TPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSL 297
Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
TG I+ E LD EET +++ V A DG +A VL+ V DVNDN P + + + + +
Sbjct: 298 TGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI- 356
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
E+ PL T IAL + D+D+ NG VTC +PF+L N + L T LD
Sbjct: 357 -----PEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLD 411
Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
E+ Y I L A D G PPL++ +F++V D NDN P F S +V I ENN G +
Sbjct: 412 RETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASI 471
Query: 486 TKVSAMDADSGPNAKINYLLGPD----APPE--FSLDCRTGMLTVVKKLDREKEDKYLFT 539
V+A D DS NA+I Y L D AP S++ TG+L ++ D E+ +
Sbjct: 472 FLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLR 531
Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
+ A D+G PPL+SN+++ + ++DQNDN P + LP G+ G+
Sbjct: 532 VTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILY--------PALPTDGSTGMELAPRSAE 583
Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
+ D D G N+ ++ +L ++ F + TG +R + +
Sbjct: 584 PGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643
Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
V +D G+ S++ +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666
Score = 247 bits (631), Expect = 4e-65
Identities = 184/567 (32%), Positives = 269/567 (47%), Gaps = 42/567 (7%)
Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
+ V + D NDN P F EI V I EN G A D D+G N+ + S
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173
Query: 295 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 345
R F L +G K P LDREE H L++ ASDGG P + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232
Query: 346 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 405
DVND+ P + V + EN+P+ T++ + D D NG VT ++ +I
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285
Query: 406 FRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 462
+L +F L + T LDYE T Y +++ A D P A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343
Query: 463 APVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTG 520
AP T + ++ SIPE+ G + D DSG N ++ + + P E S+D
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403
Query: 521 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVP 580
++T K LDRE Y T+ A D G PPL+ +F+ + D NDN P F H+ Y+ Y+
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462
Query: 581 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 633
EN PR ++ L+T D D DN+ +T S+ ++ + +I+S TGV+ SFD
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522
Query: 634 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPST 689
E+ V A D G SS+ +++ V+D NDN P + P + EL S
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582
Query: 690 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 749
PG +V +V+AVD D+G NA + Y ++ + LFA+ TG + D +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642
Query: 750 LVKANDLGQPDSLFSVVIVNLFVNESV 776
+V D GQP L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668
Score = 108 bits (271), Expect = 2e-23
Identities = 87/280 (31%), Positives = 131/280 (46%), Gaps = 16/280 (5%)
Query: 513 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV-TVFVSIIDQNDNSPVFT 571
F+L+ R+G L ++DRE+ L N + N+ + V IID NDN P F
Sbjct: 75 FALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFL 134
Query: 572 HNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNIS- 630
E N + EN L DPD G NS + L N F++ Q+G
Sbjct: 135 TEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQ-LSPNRHFSLAVQSGDDETKYPE 193
Query: 631 ------FDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYEL 684
DRE++ + + A DGG RSS+A + + VVDVND+ PVF +P Y++
Sbjct: 194 LVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLP----QYQV 249
Query: 685 VLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSI--VGGNTRDLFAIDQETGNITLMEKCDV 741
+P P GT + V A+D D G+N EV YS + +F ++ TG I+ +E D
Sbjct: 250 TVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGLDY 309
Query: 742 TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
+ + + V+A D + V+I L VN++ T+
Sbjct: 310 EETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTM 349
>gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precursor
[Homo sapiens]
Length = 817
Score = 351 bits (900), Expect = 2e-96
Identities = 230/683 (33%), Positives = 354/683 (51%), Gaps = 51/683 (7%)
Query: 6 GTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKL 65
G ++ ++LL + + A Y++ EE + +GD+ KDL L P + ++
Sbjct: 12 GFFLLSILLG-TPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR--- 65
Query: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 125
+ G L + + +G + T G RIDRE++CA R C V IL ++ L I
Sbjct: 66 IISRGRTQLFALNQRSGSLVTAG-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPI 119
Query: 126 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 185
I DINDN P F IN+ I EN+A ++ L A DPDVG N +Q+Y+L +++ F
Sbjct: 120 DVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-F 178
Query: 186 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
L V + K P+L++++ LDREE+ + + + DGG P RSSTA +QV+V D ND+
Sbjct: 179 SLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDH 238
Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 305
PVF + +V++PEN PVGT + +HA D D G N ++ +SF + + + +FHLN+
Sbjct: 239 TPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSL 297
Query: 306 TGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
TG I+ E LD EET +++ V A DG +A VL+ V DVNDN P + + + + +
Sbjct: 298 TGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI- 356
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
E+ PL T IAL + D+D+ NG VTC +PF+L N + L T LD
Sbjct: 357 -----PEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLD 411
Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
E+ Y I L A D G PPL++ +F++V D NDN P F S +V I ENN G +
Sbjct: 412 RETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASI 471
Query: 486 TKVSAMDADSGPNAKINYLLGPD----APPE--FSLDCRTGMLTVVKKLDREKEDKYLFT 539
V+A D DS NA+I Y L D AP S++ TG+L ++ D E+ +
Sbjct: 472 FLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLR 531
Query: 540 ILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL-------- 591
+ A D+G PPL+SN+++ + ++DQNDN P + LP G+ G+
Sbjct: 532 VTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILY--------PALPTDGSTGMELAPRSAE 583
Query: 592 -------ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFY 642
+ D D G N+ ++ +L ++ F + TG +R + +
Sbjct: 584 PGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643
Query: 643 VKAEDGGRVSRSSSAKVTINVVD 665
V +D G+ S++ +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666
Score = 247 bits (631), Expect = 4e-65
Identities = 184/567 (32%), Positives = 269/567 (47%), Gaps = 42/567 (7%)
Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
+ V + D NDN P F EI V I EN G A D D+G N+ + S
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173
Query: 295 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 345
R F L +G K P LDREE H L++ ASDGG P + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232
Query: 346 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 405
DVND+ P + V + EN+P+ T++ + D D NG VT ++ +I
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285
Query: 406 FRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 462
+L +F L + T LDYE T Y +++ A D P A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343
Query: 463 APVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAP--PEFSLDCRTG 520
AP T + ++ SIPE+ G + D DSG N ++ + + P E S+D
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403
Query: 521 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVP 580
++T K LDRE Y T+ A D G PPL+ +F+ + D NDN P F H+ Y+ Y+
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462
Query: 581 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 633
EN PR ++ L+T D D DN+ +T S+ ++ + +I+S TGV+ SFD
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522
Query: 634 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPST 689
E+ V A D G SS+ +++ V+D NDN P + P + EL S
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582
Query: 690 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 749
PG +V +V+AVD D+G NA + Y ++ + LFA+ TG + D +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642
Query: 750 LVKANDLGQPDSLFSVVIVNLFVNESV 776
+V D GQP L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668
Score = 108 bits (271), Expect = 2e-23
Identities = 87/280 (31%), Positives = 131/280 (46%), Gaps = 16/280 (5%)
Query: 513 FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV-TVFVSIIDQNDNSPVFT 571
F+L+ R+G L ++DRE+ L N + N+ + V IID NDN P F
Sbjct: 75 FALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFL 134
Query: 572 HNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNIS- 630
E N + EN L DPD G NS + L N F++ Q+G
Sbjct: 135 TEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQ-LSPNRHFSLAVQSGDDETKYPE 193
Query: 631 ------FDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYEL 684
DRE++ + + A DGG RSS+A + + VVDVND+ PVF +P Y++
Sbjct: 194 LVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLP----QYQV 249
Query: 685 VLPSTNP-GTVVFQVIAVDNDTGMNAEVRYSI--VGGNTRDLFAIDQETGNITLMEKCDV 741
+P P GT + V A+D D G+N EV YS + +F ++ TG I+ +E D
Sbjct: 250 TVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGLDY 309
Query: 742 TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 781
+ + + V+A D + V+I L VN++ T+
Sbjct: 310 EETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTM 349
>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
[Homo sapiens]
Length = 810
Score = 349 bits (895), Expect = 9e-96
Identities = 229/661 (34%), Positives = 344/661 (52%), Gaps = 44/661 (6%)
Query: 23 AQEKNYTIREEMPENVLIGDLLKDLNLSL--IPNKSLTTAMQFKLVYKTGDVPLIRIEED 80
+Q+ YTI EE+ +G L KDL LS+ +P + L + + + +
Sbjct: 28 SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77
Query: 81 TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 139
+G++ G RIDREK+C R C E E VA P +F +V + I+DINDNAP F
Sbjct: 78 SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130
Query: 140 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 199
A I++ I E++ K++L +A D DV N ++ Y + +Q F L E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189
Query: 200 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
L+++K LDRE + ++ + + DGG P S T + + VTD NDN PVF + VS+
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249
Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 319
EN P GTSV ++ ATD D G NA+I ++F N S I+ LF+LN TG IT LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307
Query: 320 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 379
T + L V A DGG+ A V + + D NDN P + N + E+ L T
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361
Query: 380 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAA 439
IALI V DKD+ NG VTC+T E+PF+L N + L A L+ E T +Y + ++A
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421
Query: 440 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNA 499
D GKP L+ + + + D NDNAPVF Q+ V + ENN PG + +VSA D D GPN
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481
Query: 500 KINY-LLGPDAPPE-----FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 553
+++Y +L D P S+ ++G++ + D E+ + T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541
Query: 554 VTVFVSIIDQNDNSPVFTH-------NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVT 606
V++ V + D NDN+P + + VP V + D D G N+ ++
Sbjct: 542 VSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLS 601
Query: 607 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 664
+L ++ F++ +TG +R + V DGG+ S++A + +
Sbjct: 602 YHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFA 661
Query: 665 D 665
D
Sbjct: 662 D 662
Score = 237 bits (604), Expect = 5e-62
Identities = 192/711 (27%), Positives = 332/711 (46%), Gaps = 57/711 (8%)
Query: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 202
I +IPE A S+ A D + + + +L + +++ F + + GD L+
Sbjct: 31 IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82
Query: 203 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 261
V +DRE+ ++ +E + + V + D NDN P F I++ I E+
Sbjct: 83 VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142
Query: 262 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 320
A G + A DAD+ G + K++ N +++ + + ++ +++PLDRE
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202
Query: 321 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 378
+H+L++ A DGG P + + VTD NDN P + + V L EN+P T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256
Query: 379 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLL 437
+ + TD+D N +T F + I L + N + T LD+E T Y + +
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316
Query: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
A D G + + I++ DENDNAP T + IPE++ G + + D DSG
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374
Query: 498 NAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV 554
N + + P F L+ + L + L+RE+ Y TI+A D G P L+S
Sbjct: 375 NGMVTCYTQEEVP--FKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT 432
Query: 555 TVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDEND 614
++ + I D NDN+PVF Y +V EN P ++ ++ +DPD G N V+ SIL +
Sbjct: 433 SITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDL 492
Query: 615 D-------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVN 667
+ ++ Q+GV+ +FD E+ ++ ++A D G + S++ + + V D+N
Sbjct: 493 EPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLN 552
Query: 668 DNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
DN P + P + +++V + PG +V +V+AVD D+G NA + Y ++ + L
Sbjct: 553 DNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL 612
Query: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
F++ TG + D R+LV D GQP + + +F A +
Sbjct: 613 FSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIF-------ADSLQ 665
Query: 784 ELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 834
E++ ++ P + S P ++ LV A+A ++ V+F+ AV+
Sbjct: 666 EVLPDLSDRP--------EPSDPQTELQFYLVVALA----LISVLFLLAVI 704
>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
[Homo sapiens]
Length = 927
Score = 349 bits (895), Expect = 9e-96
Identities = 229/661 (34%), Positives = 344/661 (52%), Gaps = 44/661 (6%)
Query: 23 AQEKNYTIREEMPENVLIGDLLKDLNLSL--IPNKSLTTAMQFKLVYKTGDVPLIRIEED 80
+Q+ YTI EE+ +G L KDL LS+ +P + L + + + +
Sbjct: 28 SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77
Query: 81 TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 139
+G++ G RIDREK+C R C E E VA P +F +V + I+DINDNAP F
Sbjct: 78 SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130
Query: 140 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 199
A I++ I E++ K++L +A D DV N ++ Y + +Q F L E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189
Query: 200 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 259
L+++K LDRE + ++ + + DGG P S T + + VTD NDN PVF + VS+
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249
Query: 260 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 319
EN P GTSV ++ ATD D G NA+I ++F N S I+ LF+LN TG IT LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307
Query: 320 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 379
T + L V A DGG+ A V + + D NDN P + N + E+ L T
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361
Query: 380 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAA 439
IALI V DKD+ NG VTC+T E+PF+L N + L A L+ E T +Y + ++A
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421
Query: 440 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNA 499
D GKP L+ + + + D NDNAPVF Q+ V + ENN PG + +VSA D D GPN
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481
Query: 500 KINY-LLGPDAPPE-----FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 553
+++Y +L D P S+ ++G++ + D E+ + T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541
Query: 554 VTVFVSIIDQNDNSPVFTH-------NEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVT 606
V++ V + D NDN+P + + VP V + D D G N+ ++
Sbjct: 542 VSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLS 601
Query: 607 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 664
+L ++ F++ +TG +R + V DGG+ S++A + +
Sbjct: 602 YHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFA 661
Query: 665 D 665
D
Sbjct: 662 D 662
Score = 237 bits (604), Expect = 5e-62
Identities = 192/711 (27%), Positives = 332/711 (46%), Gaps = 57/711 (8%)
Query: 144 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 202
I +IPE A S+ A D + + + +L + +++ F + + GD L+
Sbjct: 31 IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82
Query: 203 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 261
V +DRE+ ++ +E + + V + D NDN P F I++ I E+
Sbjct: 83 VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142
Query: 262 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 320
A G + A DAD+ G + K++ N +++ + + ++ +++PLDRE
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202
Query: 321 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 378
+H+L++ A DGG P + + VTD NDN P + + V L EN+P T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256
Query: 379 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLL 437
+ + TD+D N +T F + I L + N + T LD+E T Y + +
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316
Query: 438 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGP 497
A D G + + I++ DENDNAP T + IPE++ G + + D DSG
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374
Query: 498 NAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNV 554
N + + P F L+ + L + L+RE+ Y TI+A D G P L+S
Sbjct: 375 NGMVTCYTQEEVP--FKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT 432
Query: 555 TVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDEND 614
++ + I D NDN+PVF Y +V EN P ++ ++ +DPD G N V+ SIL +
Sbjct: 433 SITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDL 492
Query: 615 D-------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVN 667
+ ++ Q+GV+ +FD E+ ++ ++A D G + S++ + + V D+N
Sbjct: 493 EPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLN 552
Query: 668 DNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
DN P + P + +++V + PG +V +V+AVD D+G NA + Y ++ + L
Sbjct: 553 DNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL 612
Query: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
F++ TG + D R+LV D GQP + + +F A +
Sbjct: 613 FSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIF-------ADSLQ 665
Query: 784 ELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 834
E++ ++ P + S P ++ LV A+A ++ V+F+ AV+
Sbjct: 666 EVLPDLSDRP--------EPSDPQTELQFYLVVALA----LISVLFLLAVI 704
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 348 bits (893), Expect = 1e-95
Identities = 226/678 (33%), Positives = 353/678 (52%), Gaps = 57/678 (8%)
Query: 27 NYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFT 86
+YT++EE +G++ +DL L + + +A F+ V P + + +TG ++
Sbjct: 21 HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75
Query: 87 TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 146
+IDRE++C P C +EV + + L ++ + DINDN P FP + +
Sbjct: 76 N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129
Query: 147 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 206
I E++ +++ L +A DPDVG N +++YE I + F LDV +G++ +L+++K
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188
Query: 207 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 247
LDRE++ + + DGG QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248
Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
F + VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S AR LF L+ TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308
Query: 308 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
+ + LD EE+P +++ V A D G +PA VLV V D NDN P I + V
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
SE T +AL +VTD+D++ NG+V C ++PFRL+ F N + + T A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
E+ Y + ++A D G+P L+ S + ++V D NDNAP F+Q V + ENN PG +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
Query: 486 TKVSAMDADSGPNAKINY------LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
VSA D D G NA++ Y + G S++ G L ++ D E+ + F
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
Query: 540 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYNFYVPENLPRHGTVGL---- 591
+ A+D G P L N TV + I+DQNDN+P E LPR G
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
Query: 592 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 647
+ D D G+N+ +T SI+ +E + F +D +TG +R + R+ Q Y ++ D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662
Query: 648 GGRVSRSSSAKVTINVVD 665
G+ SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680
Score = 234 bits (596), Expect = 4e-61
Identities = 177/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)
Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
+++ V D NDN P F E ++ V I E+A GT A D D+G N+ + +
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162
Query: 295 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 333
F L+ T + +++PLDRE+ H+ ++ A DGG
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 334 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 386
L P + A++ + V D NDNVP+ D PV TV L EN P T + + T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275
Query: 387 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTKEYAIKLLAADAGK 443
D D NG V I R R +F LE + LDYE + Y + + A D G
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335
Query: 444 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY 503
+ + ++V D NDNAP + S V ++ E +PG + S D DS N ++
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395
Query: 504 LLGPDAPPEFSLDCRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 562
L D P + V + LDRE D Y T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455
Query: 563 QNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 615
NDN+P F+ Y+ YV EN + ++ TD D G N+ + SIL+
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515
Query: 616 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 674
+I+S+ G + SFD E+ + ++F V+A D G + +A V I +VD NDN P +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575
Query: 675 VP----PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 730
P + E++ S PG ++ +V AVD D G NA + YSIV GN +LF +D T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635
Query: 731 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
G + + + ++++ D GQP + +V V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683
Score = 182 bits (462), Expect = 1e-45
Identities = 183/632 (28%), Positives = 270/632 (42%), Gaps = 89/632 (14%)
Query: 252 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 310
+++ ++ E GT V + D+G + K+ V N LN TG++
Sbjct: 18 SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74
Query: 311 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
+ E +DRE+ +P+ H + L + L V + V D+NDN PS P
Sbjct: 75 VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123
Query: 364 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 413
D TV +SE+ T+ L + D D N D+EI FS
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177
Query: 414 NQFL-LETAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAMLF 453
N+F L LD E + L A D AG PP Q +A+L
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
Query: 454 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYL----LGPDA 509
I+V D NDN P F Q TVS+PEN+ PG + +++A D D G N ++ Y + P A
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
Query: 510 PPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPV 569
F L RTG L V +LD E+ Y + AKD G + ++ V V ++D NDN+P
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
Query: 570 FTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---VIR 626
+ + V E V L +VTD D +N V +L + F + S I
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYTIV 416
Query: 627 PNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVL 686
DRE +SYT V A D G + S+S + + V DVNDN P F P Y++ +
Sbjct: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPV----YDVYV 472
Query: 687 PSTN-PGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKCD 740
N PG ++ V A D D G NA++ YSI+ G + +I+ E G + + D
Sbjct: 473 TENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFD 532
Query: 741 VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI------------NELVRK 788
L V+A D G P +L VN+ + + NA I E++ +
Sbjct: 533 YEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPR 592
Query: 789 STEAPVTPNTEIADVSSPTSDYVKILVAAVAG 820
S E P T +A V + + ++ + V G
Sbjct: 593 SAE-PGYLLTRVAAVDADDGENARLTYSIVRG 623
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 348 bits (893), Expect = 1e-95
Identities = 226/678 (33%), Positives = 353/678 (52%), Gaps = 57/678 (8%)
Query: 27 NYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVYKTGDVPLIRIEEDTGEIFT 86
+YT++EE +G++ +DL L + + +A F+ V P + + +TG ++
Sbjct: 21 HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75
Query: 87 TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 146
+IDRE++C P C +EV + + L ++ + DINDN P FP + +
Sbjct: 76 N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129
Query: 147 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 206
I E++ +++ L +A DPDVG N +++YE I + F LDV +G++ +L+++K
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188
Query: 207 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 247
LDRE++ + + DGG QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248
Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
F + VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S AR LF L+ TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308
Query: 308 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 365
+ + LD EE+P +++ V A D G +PA VLV V D NDN P I + V
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367
Query: 366 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLD 425
SE T +AL +VTD+D++ NG+V C ++PFRL+ F N + + T A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
Query: 426 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 485
E+ Y + ++A D G+P L+ S + ++V D NDNAP F+Q V + ENN PG +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
Query: 486 TKVSAMDADSGPNAKINY------LLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFT 539
VSA D D G NA++ Y + G S++ G L ++ D E+ + F
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
Query: 540 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYNFYVPENLPRHGTVGL---- 591
+ A+D G P L N TV + I+DQNDN+P E LPR G
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
Query: 592 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 647
+ D D G+N+ +T SI+ +E + F +D +TG +R + R+ Q Y ++ D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662
Query: 648 GGRVSRSSSAKVTINVVD 665
G+ SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680
Score = 234 bits (596), Expect = 4e-61
Identities = 177/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)
Query: 235 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 294
+++ V D NDN P F E ++ V I E+A GT A D D+G N+ + +
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162
Query: 295 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 333
F L+ T + +++PLDRE+ H+ ++ A DGG
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 334 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 386
L P + A++ + V D NDNVP+ D PV TV L EN P T + + T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275
Query: 387 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLETAAYLDYESTKEYAIKLLAADAGK 443
D D NG V I R R +F LE + LDYE + Y + + A D G
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335
Query: 444 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY 503
+ + ++V D NDNAP + S V ++ E +PG + S D DS N ++
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395
Query: 504 LLGPDAPPEFSLDCRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 562
L D P + V + LDRE D Y T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455
Query: 563 QNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 615
NDN+P F+ Y+ YV EN + ++ TD D G N+ + SIL+
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515
Query: 616 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 674
+I+S+ G + SFD E+ + ++F V+A D G + +A V I +VD NDN P +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575
Query: 675 VP----PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 730
P + E++ S PG ++ +V AVD D G NA + YSIV GN +LF +D T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635
Query: 731 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 776
G + + + ++++ D GQP + +V V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683
Score = 182 bits (462), Expect = 1e-45
Identities = 183/632 (28%), Positives = 270/632 (42%), Gaps = 89/632 (14%)
Query: 252 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 310
+++ ++ E GT V + D+G + K+ V N LN TG++
Sbjct: 18 SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74
Query: 311 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
+ E +DRE+ +P+ H + L + L V + V D+NDN PS P
Sbjct: 75 VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123
Query: 364 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 413
D TV +SE+ T+ L + D D N D+EI FS
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177
Query: 414 NQFL-LETAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAMLF 453
N+F L LD E + L A D AG PP Q +A+L
Sbjct: 178 NRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLT 237
Query: 454 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYL----LGPDA 509
I+V D NDN P F Q TVS+PEN+ PG + +++A D D G N ++ Y + P A
Sbjct: 238 IRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA 297
Query: 510 PPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPV 569
F L RTG L V +LD E+ Y + AKD G + ++ V V ++D NDN+P
Sbjct: 298 RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPE 357
Query: 570 FTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---VIR 626
+ + V E V L +VTD D +N V +L + F + S I
Sbjct: 358 ISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYTIV 416
Query: 627 PNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVL 686
DRE +SYT V A D G + S+S + + V DVNDN P F P Y++ +
Sbjct: 417 TEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPV----YDVYV 472
Query: 687 PSTN-PGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKCD 740
N PG ++ V A D D G NA++ YSI+ G + +I+ E G + + D
Sbjct: 473 TENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFD 532
Query: 741 VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI------------NELVRK 788
L V+A D G P +L VN+ + + NA I E++ +
Sbjct: 533 YEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPR 592
Query: 789 STEAPVTPNTEIADVSSPTSDYVKILVAAVAG 820
S E P T +A V + + ++ + V G
Sbjct: 593 SAE-PGYLLTRVAAVDADDGENARLTYSIVRG 623
>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
[Homo sapiens]
Length = 837
Score = 346 bits (887), Expect = 7e-95
Identities = 214/681 (31%), Positives = 352/681 (51%), Gaps = 54/681 (7%)
Query: 12 VLLACVVFHS----GAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQFKLVY 67
+LL C+ + A++ Y++ EE + +G++ KDL L P + ++ +
Sbjct: 14 LLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLE--PRELAKRGVR---IV 68
Query: 68 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 127
G L + +G + T G RIDRE+LC + CF +E +L ++ ++ +
Sbjct: 69 SRGKTQLFAVNPRSGSLITAG-RIDREELCETV---SSCFLNME--LLVEDTLKIYGVEV 122
Query: 128 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 187
I DINDNAP F + I + E++ +++ LP A DPDVG+N +Q+Y+L N F L
Sbjct: 123 EIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQL-SPNNYFSL 181
Query: 188 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 247
+ +G K P+L+++ LDRE++ +++ + DGG P R ++V V D ND+ P
Sbjct: 182 QLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIP 241
Query: 248 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 307
+F ++ VS+PEN GT V ++ATD D G N ++ +SF N+ S A +F L++ TG
Sbjct: 242 MFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMESK-ASEIFQLDSQTG 300
Query: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367
+ ++ LD E+ +++ + DGG + +L+ V DVNDN P I I +N +
Sbjct: 301 EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSI--- 357
Query: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYE 427
EN P T IAL+ V D+D+ NG+V+CF + +PF+L + N + L T+ LD E
Sbjct: 358 ---LENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRE 414
Query: 428 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTK 487
+ Y I L A D G PPL+ +++ V D+NDN PVF S + IPENN G +
Sbjct: 415 LVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFS 474
Query: 488 VSAMDADSGPNAKINYLLGPDA------PPEFSLDCRTGMLTVVKKLDREKEDKYLFTIL 541
V+A+D DS NA + Y L D S++ TG+L ++ D E+ ++
Sbjct: 475 VTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVI 534
Query: 542 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGL---------- 591
A+D+G PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 535 ARDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 586
Query: 592 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 644
+ D D G N+ ++ +L ++ F + TG +R + + V
Sbjct: 587 YLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 646
Query: 645 AEDGGRVSRSSSAKVTINVVD 665
+D G+ S++ +T+ V D
Sbjct: 647 VQDHGQPPLSATVTLTVAVAD 667
Score = 253 bits (646), Expect = 6e-67
Identities = 211/725 (29%), Positives = 334/725 (46%), Gaps = 71/725 (9%)
Query: 139 FPATVINISIPENSAINSKYTLPAAVDPDVGIN-------GVQNYELIKSQNIFGLDVIE 191
F A I S+PE + K + + D+G+ GV+ K+Q +F ++
Sbjct: 27 FRARQIRYSVPEET---EKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQ-LFAVN--- 79
Query: 192 TPEGDKMPQLIVQKELDREEKDTYV------MKVKVEDGGFPQRSSTAILQVSVTDTNDN 245
+ LI +DREE V M++ VED ++V + D NDN
Sbjct: 80 ----PRSGSLITAGRIDREELCETVSSCFLNMELLVED-----TLKIYGVEVEIIDINDN 130
Query: 246 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVSNIARRLFHLNA 304
P F+E E+E+ + E+A G +A D D+G N+ + S N ++ R A
Sbjct: 131 APSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGA 190
Query: 305 TTGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
+ ++ LDRE+ H LL+ A DGG + + V V DVND++P
Sbjct: 191 KNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVY-- 248
Query: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF---SNQFLLE 419
V + ENI T++ ++ TD D NG V ++ + + +F S ++
Sbjct: 249 ----RVSVPENISSGTRVLMVNATDPDEGINGEVM-YSFRNMESKASEIFQLDSQTGEVQ 303
Query: 420 TAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 479
LD+E + Y +++ D G L + + I V D NDNAP T + SI EN+
Sbjct: 304 VRGSLDFEKYRFYEMEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENS 361
Query: 480 SPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTG---MLTVVKKLDREKEDKY 536
PG + ++ D DSG N +++ + P F L+ G L + LDRE Y
Sbjct: 362 PPGTVIALLNVQDQDSGENGQVSCFIPNHLP--FKLEKTYGNYYKLITSRVLDRELVQSY 419
Query: 537 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTD 596
T+ A D G PPL++ V++++ D NDN PVF H+ Y+ Y+PEN PR ++ +T D
Sbjct: 420 NITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALD 479
Query: 597 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 649
PD N+ VT S+ D+ + +I+S TGV+ SFD E+ V A D G
Sbjct: 480 PDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSG 539
Query: 650 RVSRSSSAKVTINVVDVNDNKPVFIVPP----SNCSYELVLPSTNPGTVVFQVIAVDNDT 705
SS+ +++ V+D NDN P + P + EL S PG +V +V+AVD D+
Sbjct: 540 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDS 599
Query: 706 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 765
G NA + Y ++ + LFA+ + TG + D ++V D GQP +V
Sbjct: 600 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 659
Query: 766 VIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 825
+ +V A I E++ N+E +D+S Y+ + VAAV+ V
Sbjct: 660 TL-------TVAVADSIPEVLADLGSLESLANSETSDLSL----YLVVAVAAVSCIFLVF 708
Query: 826 VVIFI 830
V++ +
Sbjct: 709 VIVLL 713
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,270,344
Number of Sequences: 37866
Number of extensions: 1774767
Number of successful extensions: 14229
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 4759
Number of HSP's gapped (non-prelim): 933
length of query: 1021
length of database: 18,247,518
effective HSP length: 112
effective length of query: 909
effective length of database: 14,006,526
effective search space: 12731932134
effective search space used: 12731932134
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.