BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|74271888 lipin 3 [Homo sapiens] (851 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|74271888 lipin 3 [Homo sapiens] 1734 0.0 gi|7662022 lipin 2 [Homo sapiens] 805 0.0 gi|22027648 lipin 1 [Homo sapiens] 748 0.0 gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 50 1e-05 gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 49 2e-05 gi|163965366 nascent polypeptide-associated complex alpha subuni... 47 7e-05 gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 45 3e-04 gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 45 3e-04 gi|55741849 WD repeat domain 22 [Homo sapiens] 43 0.001 gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 43 0.001 gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sap... 42 0.002 gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 42 0.003 gi|188536004 zinc finger protein 469 [Homo sapiens] 42 0.003 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 42 0.003 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 41 0.005 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 41 0.005 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 41 0.005 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 41 0.005 gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 41 0.005 gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 41 0.005 gi|178557736 microtubule-associated protein tau isoform 5 [Homo ... 40 0.009 gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens] 40 0.012 gi|71274152 hypothetical protein LOC388939 [Homo sapiens] 40 0.012 gi|150418009 transforming, acidic coiled-coil containing protein... 39 0.016 gi|154800453 tastin isoform 1 [Homo sapiens] 39 0.020 gi|98985819 interferon regulatory factor 7 isoform d [Homo sapiens] 39 0.027 gi|4758610 interferon regulatory factor 7 isoform a [Homo sapiens] 39 0.027 gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 39 0.027 gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapi... 39 0.027 gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like i... 38 0.035 >gi|74271888 lipin 3 [Homo sapiens] Length = 851 Score = 1734 bits (4490), Expect = 0.0 Identities = 851/851 (100%), Positives = 851/851 (100%) Query: 1 MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRS 60 MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRS Sbjct: 1 MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRS 60 Query: 61 REKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPWGGLSGFPSDS 120 REKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPWGGLSGFPSDS Sbjct: 61 REKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPWGGLSGFPSDS 120 Query: 121 QLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPEKL 180 QLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPEKL Sbjct: 121 QLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPEKL 180 Query: 181 RPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRA 240 RPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRA Sbjct: 181 RPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRA 240 Query: 241 ESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVDPLGLPIQQ 300 ESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVDPLGLPIQQ Sbjct: 241 ESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVDPLGLPIQQ 300 Query: 301 TEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQP 360 TEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQP Sbjct: 301 TEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQP 360 Query: 361 ERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLR 420 ERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLR Sbjct: 361 ERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLR 420 Query: 421 DPNPEHEPEPTLDTVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLV 480 DPNPEHEPEPTLDTVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLV Sbjct: 421 DPNPEHEPEPTLDTVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLV 480 Query: 481 VKINGKHYNWAVAAPMILSLQAFQKNLPKSTMDKLEREKMPRKGGRWWFSWRRRDFLAEE 540 VKINGKHYNWAVAAPMILSLQAFQKNLPKSTMDKLEREKMPRKGGRWWFSWRRRDFLAEE Sbjct: 481 VKINGKHYNWAVAAPMILSLQAFQKNLPKSTMDKLEREKMPRKGGRWWFSWRRRDFLAEE 540 Query: 541 RSAQKEKTAAKEQQGEKTEVLSSDDDAPDSPVILEIPSLPPSTPPSTPTYKKSLRLSSDQ 600 RSAQKEKTAAKEQQGEKTEVLSSDDDAPDSPVILEIPSLPPSTPPSTPTYKKSLRLSSDQ Sbjct: 541 RSAQKEKTAAKEQQGEKTEVLSSDDDAPDSPVILEIPSLPPSTPPSTPTYKKSLRLSSDQ 600 Query: 601 IRRLNLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTITKSDALGHILP 660 IRRLNLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTITKSDALGHILP Sbjct: 601 IRRLNLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTITKSDALGHILP 660 Query: 661 QLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGGCSLPKGPILL 720 QLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGGCSLPKGPILL Sbjct: 661 QLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGGCSLPKGPILL 720 Query: 721 SPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVFAYRQVGLP 780 SPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVFAYRQVGLP Sbjct: 721 SPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVFAYRQVGLP 780 Query: 781 ESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDLANPEYSNFCYWRE 840 ESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDLANPEYSNFCYWRE Sbjct: 781 ESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDLANPEYSNFCYWRE 840 Query: 841 PLPAVDLDTLD 851 PLPAVDLDTLD Sbjct: 841 PLPAVDLDTLD 851 >gi|7662022 lipin 2 [Homo sapiens] Length = 896 Score = 805 bits (2079), Expect = 0.0 Identities = 445/913 (48%), Positives = 582/913 (63%), Gaps = 81/913 (8%) Query: 1 MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRS 60 MNYVGQLA V TVKELY+G+N ATLSG IDV+VV+Q DGS++CSPFHVRFGKLGVLRS Sbjct: 1 MNYVGQLAGQVIVTVKELYKGINQATLSGCIDVIVVQQQDGSYQCSPFHVRFGKLGVLRS 60 Query: 61 REKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPW---------- 110 +EKV+DIE+NG VDLHMKLGD+GEAFFV+E E + E +P L TSPIP Sbjct: 61 KEKVIDIEINGSAVDLHMKLGDNGEAFFVEETEEEYEKLPAYLATSPIPTEDQFFKDIDT 120 Query: 111 -----GGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQ---KEDAVATDSS 162 GG S + E E + T S+ ++K+RRR+K KQ KE+ A+ ++ Sbjct: 121 PLVKSGGDETPSQSSDISHVLETETIF---TPSSVKKKKRRRKKYKQDSKKEEQAASAAA 177 Query: 163 PEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPK-----DIYPYSDGEWPPQASLSAG 217 + + G S+ + L+E+ +P D YP SDG+W P + + Sbjct: 178 EDTCDVGVSSDDDKGAQAARGSSNASLKEEECKEPLLFHSGDHYPLSDGDWSPLET-TYP 236 Query: 218 ELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPR 277 + PKSDSELEV+ P S LR+ESHM+W WG P+ + + E S PR Sbjct: 237 QTACPKSDSELEVK-PAESLLRSESHMEWTWGGFPESTKVSKRERS---------DHHPR 286 Query: 278 GGPSTPSTSVAGGVDPL-GLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGD 336 TPS + V P I + E A ++ T+V P T+ S S + Sbjct: 287 TATITPSENTHFRVIPSEDNLISEVEKDASMEDTV--CTIVKPKPRALGTQMSDPTSVAE 344 Query: 337 MGLPPASKSW-----------SWATLEVPV---PTGQPERVSRGKGSPKRSQHLGPSDIY 382 + PP + + A E P P + + S+ KG KRSQH GP DIY Sbjct: 345 LLEPPLESTQISSMLDADHLPNAALAEAPSESKPAAKVDSPSKKKGVHKRSQHQGPDDIY 404 Query: 383 LDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLRDPNP----------EHEPEPTL 432 LDDL L+ E AALYFP+S+S G+R+W E + + P E + + Sbjct: 405 LDDLKGLEPEVAALYFPKSESEPGSRQWPESDTLSGSQSPQSVGSAAADSGTECLSDSAM 464 Query: 433 DTVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLVVKINGKHYNWAV 492 D D + LSLCGGL+++ +IS EKF +H ++Y + +NPGL+D+PNLV++I ++YNWA+ Sbjct: 465 DLPD-VTLSLCGGLSENGEISKEKFMEHIITYHEFAENPGLIDNPNLVIRIYNRYYNWAL 523 Query: 493 AAPMILSLQAFQKNLPKSTMDKLEREKMPRKGGRWWFSWRRRDFLAEERSAQKE------ 546 AAPMILSLQ FQK+LPK+T++ ++KMP+K GRWWF WR+R+ + ++ KE Sbjct: 524 AAPMILSLQVFQKSLPKATVESWVKDKMPKKSGRWWF-WRKRESMTKQLPESKEGKSEAP 582 Query: 547 -----KTAAKEQQGEKTEV--LSSDDDAPDSPVILEIPSLP--PSTPPSTPTYKKSLRLS 597 +++KE G + SSD+ + + + + +P P + ST +YKKSLRLS Sbjct: 583 PASDLPSSSKEPAGARPAENDSSSDEGSQELEESITVDPIPTEPLSHGSTTSYKKSLRLS 642 Query: 598 SDQIRRLNLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTITKSDALGH 657 SDQI +L L +G NDVVFS+TTQYQGTCRC TIYLW W+DK++ISDIDGTITKSDALG Sbjct: 643 SDQIAKLKLHDGPNDVVFSITTQYQGTCRCAGTIYLWNWNDKIIISDIDGTITKSDALGQ 702 Query: 658 ILPQLGKDWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGGCSLPKGP 717 ILPQLGKDWTHQGI LYH I NGYKFLYCSARAIGMAD+T+GYL WV++ G LP+GP Sbjct: 703 ILPQLGKDWTHQGIAKLYHSINENGYKFLYCSARAIGMADMTRGYLHWVNDKGTILPRGP 762 Query: 718 ILLSPSSLFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVFAYRQV 777 ++LSPSSLFSA HREVIEKKPE FK+ CL+DI+ LF P QPFYAAFGNRPNDV+AY QV Sbjct: 763 LMLSPSSLFSAFHREVIEKKPEKFKIECLNDIKNLFAPSKQPFYAAFGNRPNDVYAYTQV 822 Query: 778 GLPESRIFTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDLANPEYSNFCY 837 G+P+ RIFTVNP+GELIQE K +KS+Y RL E+VE +FP +++ ++ PE+S+FCY Sbjct: 823 GVPDCRIFTVNPKGELIQERTKGNKSSYHRLSELVEHVFPLLSKEQNSAFPCPEFSSFCY 882 Query: 838 WREPLPAVDLDTL 850 WR+P+P VDLD L Sbjct: 883 WRDPIPEVDLDDL 895 >gi|22027648 lipin 1 [Homo sapiens] Length = 890 Score = 748 bits (1932), Expect = 0.0 Identities = 429/900 (47%), Positives = 563/900 (62%), Gaps = 79/900 (8%) Query: 1 MNYVGQLAETVFGTVKELYRGLNPATLSGGIDVLVVKQVDGSFRCSPFHVRFGKLGVLRS 60 MNYVGQLA VF TVKELY+GLNPATLSG ID++V++Q +G+ +CSPFHVRFGK+GVLRS Sbjct: 1 MNYVGQLAGQVFVTVKELYKGLNPATLSGCIDIIVIRQPNGNLQCSPFHVRFGKMGVLRS 60 Query: 61 REKVVDIELNGEPVDLHMKLGDSGEAFFVQELESDDEHVPPGLCTSPIPWGGLSGFPSDS 120 REKVVDIE+NGE VDLHMKLGD+GEAFFVQE ++D E +P L TSPI G S Sbjct: 61 REKVVDIEINGESVDLHMKLGDNGEAFFVQETDNDQEVIPMHLATSPILSEGASRMECQL 120 Query: 121 QLGTASEPEGL-------VMA-----GTASTGRRKRRRRRKPK-------------QKED 155 + G+ GL V+A ++S +++R+RRRK + + ED Sbjct: 121 KRGSVDRMRGLDPSTPAQVIAPSETPSSSSVVKKRRKRRRKSQLDSLKRDDNMNTSEDED 180 Query: 156 AVATDSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSS--LQPKDI-YPYSDGEWPPQA 212 + S +E ES +LP + P + E S + P+ YP SD EW P Sbjct: 181 MFPIEMSSDEAMELLESSRTLPNDIPPFQDDIPEENLSLAVIYPQSASYPNSDREWSPTP 240 Query: 213 SLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGA 272 S S ++PKSDSEL ++ E + + M W WG LP+ A++ P + Sbjct: 241 SPSGSRPSTPKSDSELVSKSTERTGQK-NPEMLWLWGELPQAAKSSSPH-------KMKE 292 Query: 273 TSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQ 332 +SP S + + + ++ +D + PTLVG L +++ Q Sbjct: 293 SSP------LSSRKICDKSHFQAIHSESSDTFSD-----QSPTLVGGALLDQNKPQTEMQ 341 Query: 333 SSGDMGLPPASKSWSWATL--EVPVPTGQPERVSRGKGSP-----KRSQHLGPSDIYLDD 385 + L + + E+ P+ + + SP KRS+HLG +YLDD Sbjct: 342 FVNEEDLETLGAAAPLLPMIEELKPPSASVVQTANKTDSPSRKRDKRSRHLGADGVYLDD 401 Query: 386 LPSLDSENAALYFPQSD--SGL-------GARRWSEPSSQKSLRDPNPEHEPEPTLD--- 433 L +D E AALYFP++ SGL GAR S S +S+ + E T D Sbjct: 402 LTDMDPEVAALYFPKNGDPSGLAKHASDNGAR--SANQSPQSVGSSGVDSGVESTSDGLR 459 Query: 434 TVDTIALSLCGGLADSRDISLEKFNQHSVSYQDLTKNPGLLDDPNLVVKINGKHYNWAVA 493 + +IA+SLCGGL+D R+I+ + F + +VSYQ NP ++DDPNLVVKI K+YNW A Sbjct: 460 DLPSIAISLCGGLSDHREITKDAFLEQAVSYQQFVDNPAIIDDPNLVVKIGSKYYNWTTA 519 Query: 494 APMILSLQAFQKNLPKSTMDKLEREKMPRKGGRWWFSWRRRDFLAEERSAQKEKTAAKEQ 553 AP++L++QAFQK LPK+T++ + R+KMP+KGGRWWFSWR R+ +E S ++ A K Sbjct: 520 APLLLAMQAFQKPLPKATVESIMRDKMPKKGGRWWFSWRGRNTTIKEESKPEQCLAGKAH 579 Query: 554 Q-GEKTEVLS------SDDDAPDSPVILEIPSLPPSTP--PSTPTYKKSLRLSSDQIRRL 604 GE+ LS + + D PS P P+ +YKK+LRL+S+Q++ L Sbjct: 580 STGEQPPQLSLATRVKHESSSSDEERAAAKPSNAGHLPLLPNV-SYKKTLRLTSEQLKSL 638 Query: 605 NLQEGANDVVFSVTTQYQGTCRCKATIYLWKWDDKVVISDIDGTITKSDALGHILPQLGK 664 L+ G NDVVFSVTTQYQGTCRC+ TIYLW WDDKV+ISDIDGTIT+SD LGHILP LGK Sbjct: 639 KLKNGPNDVVFSVTTQYQGTCRCEGTIYLWNWDDKVIISDIDGTITRSDTLGHILPTLGK 698 Query: 665 DWTHQGITSLYHKIQLNGYKFLYCSARAIGMADLTKGYLQWVSEGGCSLPKGPILLSPSS 724 DWTHQGI LYHK+ NGYKFLYCSARAIGMAD+T+GYL WV+E G LP+GP+LLSPSS Sbjct: 699 DWTHQGIAKLYHKVSQNGYKFLYCSARAIGMADMTRGYLHWVNERGTVLPQGPLLLSPSS 758 Query: 725 LFSALHREVIEKKPEVFKVACLSDIQQLFLPHGQPFYAAFGNRPNDVFAYRQVGLPESRI 784 LFSALHREVIEKKPE FKV CL+DI+ LF P+ +PFYAAFGNRP DV++Y+QVG+ +RI Sbjct: 759 LFSALHREVIEKKPEKFKVQCLTDIKNLFFPNTEPFYAAFGNRPADVYSYKQVGVSLNRI 818 Query: 785 FTVNPRGELIQELIKNHKSTYERLGEVVELLFPPVARGPSTDL-ANPEYSNFCYWREPLP 843 FTVNP+GEL+QE K + S+Y RL EVV+ +FP + R S+D + +SNF +WREPLP Sbjct: 819 FTVNPKGELVQEHAKTNISSYVRLCEVVDHVFPLLKRSHSSDFPCSDTFSNFTFWREPLP 878 >gi|4885407 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 [Homo sapiens] Length = 1203 Score = 49.7 bits (117), Expect = 1e-05 Identities = 97/372 (26%), Positives = 121/372 (32%), Gaps = 65/372 (17%) Query: 81 GDSGEAFFVQELESDDEHVPPGLCTSPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTG 140 G S A L S PPG C SP +G + + G + L G+ S+ Sbjct: 864 GFSAPAGLSPLLPSSSSSPPPGACGSPSAPTPSAGVAATTIAGFGHFHKAL--GGSLSSS 921 Query: 141 RRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDI 200 +P + A P GA L LPE P PP + S Sbjct: 922 DSPLLTPLQPGARSPQAA---QPSPAPPGARGGLGLPEHFLPPPPSSRSPSSS------- 971 Query: 201 YPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERP 260 P G+ P LS G T P S E R PEP L VA A Sbjct: 972 -PGQLGQ--PPGELSLGLATGPLSTPETPPRQPEPPSL---------------VAGASGG 1013 Query: 261 ESSVVLEGRAG------ATSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDP 314 S V R G + PPR PS P + +G L LP A P + P Sbjct: 1014 ASPVGFTPRGGLSPPGHSPGPPRTFPSAPPRA-SGSHGSLLLP------PASSPPPPQVP 1066 Query: 315 TLVGPPLHTPE--TEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPE---------RV 363 G P TP T++ K S+ LP TL P E R Sbjct: 1067 QRRGTPPLTPGRLTQDLKLISASQPALPQDGAQ----TLRRASPHSSGESMAAFPLFPRA 1122 Query: 364 SRGKGSPKRSQHLGPSDIYLDDLP----SLDSENAALYFPQSDSGLGARRWSE---PSSQ 416 G G S LGP +P +L + ++ P S GAR S P + Sbjct: 1123 GGGSGGSGSSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARATSSGGPPLTA 1182 Query: 417 KSLRDPNPEHEP 428 R+P EP Sbjct: 1183 GPQREPGARPEP 1194 >gi|50428935 BPY2 interacting protein 1 [Homo sapiens] Length = 1059 Score = 49.3 bits (116), Expect = 2e-05 Identities = 129/523 (24%), Positives = 191/523 (36%), Gaps = 115/523 (21%) Query: 125 ASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDS---SPEELEAGAESELSL--PEK 179 +S+ EGL+ R R++P + E T+ +P EL+ + +S P + Sbjct: 481 SSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPRE 540 Query: 180 LRPEPPGVQLEEKSSLQ----PKDIYPYSDGEWPPQA-------SLSAGELTSPK----S 224 +R V +K++ Q P+ S +PP A SL GE + P S Sbjct: 541 VRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGS 600 Query: 225 DSELEVRTP--EPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPST 282 + V TP E P+ A LE A+S PR P T Sbjct: 601 PASQLVATPSLELGPIPAGEEK--------------------ALELPLAASSIPR--PRT 638 Query: 283 PST----SVAGGVDPLGL-PIQQTEAGADLQPDTEDPTLVGPPL-------HTPETEESK 330 PS S A G + L L P++ EAG D P PT+ P L H+ E +ES Sbjct: 639 PSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESL 698 Query: 331 TQSSGDMGLPPASKSWSWATLEVPVP------TGQPERVSRGKGSPKRSQHLGPSDIYLD 384 + S + LPP++ + S A L +P+ + P V SP +H + Sbjct: 699 SVSFEQV-LPPSAPT-SEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPA 756 Query: 385 DLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLRDPNPEHEPEPTLDTVDTIALSLCG 444 S +++ + GLGA S +SL PTL D + L+ Sbjct: 757 PASPGSSNDSSARSQERAGGLGAEETPPTSVSESL----------PTLSDSDPVPLA--P 804 Query: 445 GLADSRDISLEKFN--QHSVSYQDLTKNPGLLDDPNLVVKINGKHY-------------- 488 G ADS D E F +H D K P L DP+ + ++ + Sbjct: 805 GAADS-DEDTEGFGVPRHD-PLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRT 862 Query: 489 -------NWAVAAPMILSLQAFQ-KNLP---KSTMDKLEREKMPRKGGRWWFSWRRRDFL 537 N AAP + A + K L +++ R + KGGR S Sbjct: 863 RKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLS------- 915 Query: 538 AEERSAQKEKTAAKEQQGEKTEVLSSDDDAPDSPVILEIPSLP 580 R + KTA + G + P SPV L++ LP Sbjct: 916 ---RKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLP 955 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 47.0 bits (110), Expect = 7e-05 Identities = 54/207 (26%), Positives = 72/207 (34%), Gaps = 25/207 (12%) Query: 174 LSLPEKLRPEPPGVQL----EEKSSLQPKDIYPYS-DGEWPPQASLSAGELTSPKSDSEL 228 ++LP K P P V L E ++ PK S P +A + P S S Sbjct: 878 VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPK 937 Query: 229 EVRTPE----PSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPS 284 TP PSP + W P A P+ GA +PP P +P Sbjct: 938 GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997 Query: 285 TSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASK 344 G P + GA P P+ G P TP + + T + PP+ K Sbjct: 998 ----------GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA---ATPPSPK 1044 Query: 345 SWSWATLEVPVPTGQPERVSRGKGSPK 371 AT P+P G P + SPK Sbjct: 1045 GSPAAT---PLPKGAPTTPAATLPSPK 1068 Score = 37.7 bits (86), Expect = 0.045 Identities = 56/242 (23%), Positives = 86/242 (35%), Gaps = 28/242 (11%) Query: 209 PPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRL--PKVARAERPESSVVL 266 PP+ + + T P L +P+ +P + G L P A ++ Sbjct: 1167 PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226 Query: 267 EGRAGATSP-PRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVG------- 318 + G +P P+G P+TP+ A P G P GA P P+L G Sbjct: 1227 SPKGGLATPSPKGAPTTPA---ATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283 Query: 319 -----PPLHTPETEESKTQSSGDMGLP------PASKSWSWATLEVPVPTGQPERVSRGK 367 P + TP + + +S G P P S S T P P G P + Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT---PPPKGAPTPPAVTP 1340 Query: 368 GSPKRSQHLGPSDIYLDDLPSLDSENAALYFP-QSDSGLGARRWSEPSSQKSLRDPNPEH 426 SPK + L + P+ S P + S G + PS ++ P+P+ Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG 1400 Query: 427 EP 428 +P Sbjct: 1401 DP 1402 Score = 36.2 bits (82), Expect = 0.13 Identities = 79/355 (22%), Positives = 112/355 (31%), Gaps = 37/355 (10%) Query: 100 PPGLCTSP--IPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAV 157 P G+ P P + P + P+ S+ +K R PK + Sbjct: 875 PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934 Query: 158 ATDSSPEELEAGAESELSLPE----KLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQAS 213 + +P A S P K P PP S + P G P A+ Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT---PPSPKGGPATPSPKGAPTPPAA 991 Query: 214 LSAGELTSPKSDSELEVRTPE----PSPLRAESHMQWAWGR-LPKVARAERPESSVVLEG 268 P + S TP PSP + + + G P A P+ S Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP 1051 Query: 269 --RAGATSP------PRGGPSTPSTS------VAGGVDPLGLPIQQTEAGADLQPDTEDP 314 + T+P P+GGP+TPS A P G P + GA + P P Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111 Query: 315 TLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPKRSQ 374 + G L TP + + T + PP+ K L P P G P + SPK Sbjct: 1112 SPKG-GLATPPHKGAPTTPA---ATPPSPK----GGLATPPPKGAPTTPAATPPSPKGGL 1163 Query: 375 HL-GPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLRDPNPEHEP 428 P + S L P + PS + L P+P+ P Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1218 Score = 33.9 bits (76), Expect = 0.66 Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 11/100 (11%) Query: 272 ATSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKT 331 AT PP+G P+TP+ + L P GA P P+ G L TP + + T Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATP---PPKGAPTTPAATPPSPKG-GLATPSPKGAPT 1196 Query: 332 QSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPK 371 + PP+ K L P P G P + SPK Sbjct: 1197 TPA---ATPPSPK----GGLATPSPKGAPTTPAATPPSPK 1229 >gi|48255931 hepatoma-derived growth factor-related protein 2 isoform 1 [Homo sapiens] Length = 671 Score = 45.1 bits (105), Expect = 3e-04 Identities = 50/189 (26%), Positives = 73/189 (38%), Gaps = 19/189 (10%) Query: 91 ELESDDEHVPPGLCTSPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKP 150 + + DDE T+ SDS +S+ GL A +R R+ Sbjct: 115 DADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKAS 174 Query: 151 KQKEDAVATDSSPEELEAGAESELSLPEKLRPE-----------PPGVQLEEKS-SLQPK 198 + A + S E E+ +ESE + + PE P G + ++K+ S Sbjct: 175 SDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDS 234 Query: 199 DIYPYSDGEWPPQA----SLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKV 254 D SDG P S S+ +S SDS++ V+ P AE + GR PK Sbjct: 235 DSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPK- 293 Query: 255 ARAERPESS 263 ERP SS Sbjct: 294 --PERPPSS 300 >gi|14249158 hepatoma-derived growth factor-related protein 2 isoform 2 [Homo sapiens] Length = 670 Score = 45.1 bits (105), Expect = 3e-04 Identities = 50/189 (26%), Positives = 73/189 (38%), Gaps = 19/189 (10%) Query: 91 ELESDDEHVPPGLCTSPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKP 150 + + DDE T+ SDS +S+ GL A +R R+ Sbjct: 115 DADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKAS 174 Query: 151 KQKEDAVATDSSPEELEAGAESELSLPEKLRPE-----------PPGVQLEEKS-SLQPK 198 + A + S E E+ +ESE + + PE P G + ++K+ S Sbjct: 175 SDLDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDS 234 Query: 199 DIYPYSDGEWPPQA----SLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKV 254 D SDG P S S+ +S SDS++ V+ P AE + GR PK Sbjct: 235 DSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPK- 293 Query: 255 ARAERPESS 263 ERP SS Sbjct: 294 --PERPPSS 300 >gi|55741849 WD repeat domain 22 [Homo sapiens] Length = 942 Score = 43.1 bits (100), Expect = 0.001 Identities = 86/387 (22%), Positives = 138/387 (35%), Gaps = 73/387 (18%) Query: 89 VQELESDDEHVPPGLCTSPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRR 148 V E+E D + P SP S S ++SE E + AST +R RRR Sbjct: 537 VCEVELDTDLFPRPRSPSP------EDESSSSSSSSSSEDEEELNERRASTWQRNAMRRR 590 Query: 149 KPKQKEDAVATDSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEW 208 + +ED + P G ++ + P +++++ SS Sbjct: 591 QKTTREDKPSAPIKPTNTYIGEDNY---------DYPQIKVDDLSSSPTSS--------- 632 Query: 209 PPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVL-- 266 P+ S S E+ ++ ++ + E +A + W R ++ + + L Sbjct: 633 -PERSTSTLEIQPSRASPTSDIESVERKIYKA-----YKWLRYSYISYSNNKDGETSLVT 686 Query: 267 ----EGRAGATSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLH 322 EGRAG + PS+ + L I + DL P+ G Sbjct: 687 GEADEGRAGTSHKDNPAPSSSKEAC--------LNIAMAQRNQDLPPE-------GCSKD 731 Query: 323 TPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDI- 381 T + E +T S+G P + S A EVP T Q S P ++ L + Sbjct: 732 TFKEETPRTPSNG-----PGHEHSSHAWAEVPEGTSQDTGNSGSVEHPFETKKLNGKALS 786 Query: 382 -YLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSL--------------RDPNPEH 426 ++ PS A+ S SG R S+ S ++SL R P+P H Sbjct: 787 SRAEEPPSPPVPKASGSTLNSGSGNCPRTQSDDSEERSLETICANHNNGRLHPRPPHP-H 845 Query: 427 EPEPTLDTVDTIALSLCGGLADSRDIS 453 L ++ +A S G RD S Sbjct: 846 NNGQNLGELEVVAYSSPGHSDTDRDNS 872 >gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 673 Score = 43.1 bits (100), Expect = 0.001 Identities = 60/210 (28%), Positives = 81/210 (38%), Gaps = 24/210 (11%) Query: 209 PPQASLS-----AGELTSPK-------SDSELEVRTPEPSPLRAESHMQWAWGRLPKVAR 256 PP+ASL A + SP S L RTP + L+ LP+ + Sbjct: 53 PPRASLKGTTSMASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASL 112 Query: 257 AERPESSVVLEGRAGA---TSPPRGGPS-TPSTSVAGGVDPLGLPIQQTEAGADLQ--PD 310 RP ++ + + A T+P R S TPST+ A + P + +T A L P Sbjct: 113 MRRPSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTM-PSRASLTRTPPRASLTMTPS 171 Query: 311 TEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWA----TLEVPVPTGQPERVSRG 366 T T PP +P S+T +G +K S A TL PTG P R S Sbjct: 172 TASLTRT-PPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPT 230 Query: 367 KGSPKRSQHLGPSDIYLDDLPSLDSENAAL 396 P+ S + PS L P S L Sbjct: 231 GSPPRASLSMMPSTALLIRTPPRASPTGML 260 Score = 30.8 bits (68), Expect = 5.6 Identities = 44/183 (24%), Positives = 57/183 (31%), Gaps = 23/183 (12%) Query: 210 PQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGR 269 P S S LT S + P SP S R P A S + Sbjct: 367 PTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLT--RKPPRASPTGMLSRTSITKM 424 Query: 270 AGATSPPRGGPSTPSTSVAGGVDPLGLPIQ------QTEAGADLQPDTEDPT---LVGPP 320 SP R P T P G P + Q+ A P T PT P Sbjct: 425 DSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASP 484 Query: 321 LHTPETEE----------SKTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSP 370 +P +K +S+ + P+ S +W T PTG P + GSP Sbjct: 485 TGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTW-TPSTASPTGSPS-TALAMGSP 542 Query: 371 KRS 373 R+ Sbjct: 543 SRA 545 >gi|7662146 DnaJ (Hsp40) homolog, subfamily C, member 6 [Homo sapiens] Length = 913 Score = 42.0 bits (97), Expect = 0.002 Identities = 83/339 (24%), Positives = 111/339 (32%), Gaps = 77/339 (22%) Query: 118 SDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEA-GAESELSL 176 SD +L T S P G + K +KP +K+ A PE+++ G E Sbjct: 456 SDDELLTLSSPHG-------NANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMS 508 Query: 177 PEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPS 236 P P E S D++ P QA S E S TP S Sbjct: 509 NSFSPPAAPPTNSELLS-----DLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRS 563 Query: 237 PLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVDPLGL 296 A +S L GAT P G PS PS G D LG Sbjct: 564 --------------------ATSTSASPTLRVGEGATFDPFGAPSKPS-----GQDLLGS 598 Query: 297 PIQQTEAGAD--LQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVP 354 + + A +D LQP T P+ P +H T Q P S W W Sbjct: 599 FLNTSSASSDPFLQP-TRSPS---PTVHASSTPAVNIQ-------PDVSGGWDWHAKPGG 647 Query: 355 VPTGQPERVSRGKGS-------PKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGA 407 G + GS + Q L P DL +L S + A P + +GLG Sbjct: 648 FGMGSKSAATSPTGSSHGTPTHQSKPQTLDP----FADLGTLGSSSFASK-PTTPTGLGG 702 Query: 408 RRWSEPSSQKSLRDP--------------NPEHEPEPTL 432 S QK+ P P+ +P+P++ Sbjct: 703 GFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSM 741 >gi|222352122 hypothetical protein LOC284297 [Homo sapiens] Length = 1573 Score = 41.6 bits (96), Expect = 0.003 Identities = 59/231 (25%), Positives = 84/231 (36%), Gaps = 29/231 (12%) Query: 213 SLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGA 272 +L AG SP S L V SP + W R P+ A A R G + + Sbjct: 961 TLGAGTTRSPGSPPTLRVHGDTGSPRKP-----WPERRPPRPA-ATRTAPPTPSPGPSAS 1014 Query: 273 TSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPP---LHTPETEES 329 PP GP+ S S L + T D P T DP P L +P+ S Sbjct: 1015 PGPP--GPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALS 1072 Query: 330 KTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDDLPSL 389 SS L P P+PT P+ ++ +P L P+ + +P Sbjct: 1073 TPDSSVVPALTPEPS-------PTPLPT-LPKELTSDPSTPSEVTSLSPTS---EQVPES 1121 Query: 390 DSENAALYFPQSDSGLGARRWSEPSSQKSLRDPNPEHEPEPTL--DTVDTI 438 D+ P S + R +PS P+P P+PT+ D + T+ Sbjct: 1122 DTTPDLDTTPYSSTVSEYSRSPDPSP-----SPHPTTTPDPTMAPDPITTL 1167 >gi|188536004 zinc finger protein 469 [Homo sapiens] Length = 3925 Score = 41.6 bits (96), Expect = 0.003 Identities = 72/307 (23%), Positives = 104/307 (33%), Gaps = 50/307 (16%) Query: 116 FPSDSQLGTASEPEGLVMAGTASTGRRKRR----------RRRKPKQKEDAVATDSSPEE 165 F D G A+E G G AS G R RR R R+P+ + D +P Sbjct: 954 FRKDLDSGGAAEGSGSGGGGRAS-GLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRV 1012 Query: 166 LEAGAESELSLPEKLRPEPP--------------GVQL-----EEKSSLQPKDIYPYS-- 204 A A E + + R PP G +L ++K+ L+ D S Sbjct: 1013 PRAAALPEETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEE 1072 Query: 205 DGEWPPQASLSAGELTSPKSDSELEV----RTPEPSPLRAESHMQWAWGRLPKVARAERP 260 D + PP+ G + E+E+ R EP R + + P A E P Sbjct: 1073 DEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAP--ANPEEP 1130 Query: 261 ESSVVLEGRAGATSPP-----------RGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQP 309 S GR+ P GGP DPL +P TE + +P Sbjct: 1131 GGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVP-TNTETSEETRP 1189 Query: 310 DTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGS 369 + P P E+ T+ + + PPA+ + + QP G+ Sbjct: 1190 SLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGT 1249 Query: 370 PKRSQHL 376 PK S L Sbjct: 1250 PKPSGSL 1256 Score = 30.0 bits (66), Expect = 9.5 Identities = 68/287 (23%), Positives = 98/287 (34%), Gaps = 47/287 (16%) Query: 95 DDEHVPPGLCTSPI-PWGGLSGFPSDSQLGTASEPE----GLVMAGTAS----TGRRKRR 145 D PP L TSP P L+G + +P G V A T + T + Sbjct: 2163 DSPVAPPSLTTSPCDPKEALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTL 2222 Query: 146 RRRKPKQKE---DAVATDSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYP 202 R + +KE ++ +SP A + S L P G + + L D P Sbjct: 2223 RIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPD--P 2280 Query: 203 YSDGEWP---PQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAER 259 S G P P SP + + L R E A P + Sbjct: 2281 QSRGAPPHTNPDRMPRGHSSYSPSNTARLGHR---------EGQAVTAVPTEPPTLQGAG 2331 Query: 260 PESSVVLEGRAGATSPPRGGPSTPSTSVAGGV-------DPLGLPIQQTEA----GADLQ 308 P+S LEG G +S P TP T +G GL + +T A +D Q Sbjct: 2332 PDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQ 2391 Query: 309 PDT-------EDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSW 348 D+ T G PL ++ K +S G P ++++ W Sbjct: 2392 SDSPQSHRNASHQTPQGDPL---GPQDLKQRSRGYKKKPASTENGQW 2435 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 41.6 bits (96), Expect = 0.003 Identities = 71/316 (22%), Positives = 117/316 (37%), Gaps = 69/316 (21%) Query: 152 QKEDAVATDSSPEELEAGAESELSLPE----KLRPEPPGVQLEEKSSLQPK---DIYPYS 204 + ED A ++ E EA E++ PE + +P+ G + +E K D P S Sbjct: 1996 ESEDVEAPEAEGEMQEAEEEAQ---PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPES 2052 Query: 205 DGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRL-PKVARAERPESS 263 DG P+A A E ++ E++ E P + Q A G P+ E PE+ Sbjct: 2053 DGVEAPEAEEEAQE-----AEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107 Query: 264 VVLEGRAGATSPPRGGPSTPST------SVAGGVDPLGLPIQQTEAGADLQPDTE----- 312 + G +P G + P + G P ++ +A + QP++E Sbjct: 2108 GEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQ 2167 Query: 313 ------DPTLVGPPLHTPETE-ESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSR 365 P L G + PE E E++ +S G +E P G+ + Sbjct: 2168 EAEEEAQPELEG--VEAPEAEGEAQPESEG---------------IEAPEAEGEAQPELE 2210 Query: 366 GKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSLRD---- 421 G +P+ + P + + + ++E A P+S+ + P Q SL D Sbjct: 2211 GVEAPEAEEEAQPEP---EGVETPEAEGEAQ--PESEGETQGEKKGSP--QVSLGDGQSE 2263 Query: 422 -------PNPEHEPEP 430 P PE P P Sbjct: 2264 EASESSSPVPEDRPTP 2279 Score = 40.8 bits (94), Expect = 0.005 Identities = 61/260 (23%), Positives = 100/260 (38%), Gaps = 24/260 (9%) Query: 120 SQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPE- 178 S+LG A E EG ++ TG + Q E A D P + + GAE + PE Sbjct: 1785 SELGEA-EQEGEGISERGETGGQGSGHEDN-LQGEAAAGGDQDPGQSD-GAEG-IEAPEA 1840 Query: 179 --KLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPS 236 + +PE GV+ E + ++GE P++ ++ +P+++ E + + + Sbjct: 1841 EGEAQPESEGVEAPEAEGDAQE-----AEGEAQPESE----DVEAPEAEGEAQPESEDVE 1891 Query: 237 PLRAESHMQ--WAWGRLPKVARAERPES-SVVLEGRAGATSPPRGGPSTPSTSVA----- 288 AE +Q P+ + +PE+ SV G P G A Sbjct: 1892 TPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAE 1951 Query: 289 GGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSW 348 G P I+ EA + QP++ED + + T E E S D+ P A Sbjct: 1952 GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011 Query: 349 ATLEVPVPTGQPERVSRGKG 368 A E + E + +G Sbjct: 2012 AEEEAQPESDGVEAQPKSEG 2031 Score = 31.6 bits (70), Expect = 3.3 Identities = 55/222 (24%), Positives = 77/222 (34%), Gaps = 54/222 (24%) Query: 154 EDAVATDSSPEELEAGAESELSLPEKLRPEPP---------GVQLEEKSSLQPKDIYPYS 204 E+ V + EE + G E E E ++ E GVQLEE + Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETE-------G 1346 Query: 205 DGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSV 264 +G+ +A L E T + E V+ E E PE + Sbjct: 1347 EGQQEEEAQLEEIEETGGEGLQEEGVQLEEVK---------------------EGPEGGL 1385 Query: 265 ----VLEGRAGATSPPRGGPSTPSTSVAGGVDPLGL----PIQQTEAG---ADLQP---- 309 + EG P G S A D G P+Q+ EAG A +P Sbjct: 1386 QGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAE 1445 Query: 310 DTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATL 351 TE+PT PP H ET+ S ++ L P + AT+ Sbjct: 1446 GTEEPT--EPPSHLSETDPSASERQSGSQLEPGLEKPPGATM 1485 Score = 31.2 bits (69), Expect = 4.3 Identities = 58/228 (25%), Positives = 81/228 (35%), Gaps = 40/228 (17%) Query: 119 DSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLP- 177 D++ E EG+ + + P+ + +A E EA E++ L Sbjct: 2152 DAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEG 2211 Query: 178 -------EKLRPEPPGVQLEEKSSLQPKDIYPYSDGE------WPPQASLSAG--ELTSP 222 E+ +PEP GV+ E + P S+GE PQ SL G E S Sbjct: 2212 VEAPEAEEEAQPEPEGVETPEAEG----EAQPESEGETQGEKKGSPQVSLGDGQSEEASE 2267 Query: 223 KSDSELEVR-TPEPSPLRAESHMQWAWGRLPKVARA--------ERPESSVVLEGRAGAT 273 S E R TP PSP H + P +RA + E+ VL Sbjct: 2268 SSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPD 2327 Query: 274 SPPRGGPST--------PSTSVAGGVD-PLG--LPIQQTEAGADLQPD 310 + G P P +S + + PLG P Q G DLQ D Sbjct: 2328 AKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQED 2375 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 40.8 bits (94), Expect = 0.005 Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 18/215 (8%) Query: 150 PKQKEDAVATDSSPEELEAGAESELSLPEKLRP-EPPGVQLEEKSSLQPKDIYPYSDGEW 208 PK+ + +P + A + P P EP +E + PK + P + Sbjct: 439 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT---- 494 Query: 209 PPQASLSAGELTSPKSDSELEVRTPE-PSPLRAESHMQWAWGRLPKVARAERPESSVVLE 267 P + + + E +P + EL TPE P+P E PK A P+ Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT----PKAAAPNTPKEPAPTT 550 Query: 268 GRAGA-TSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPET 326 + A T+P P+TP + P G T +P P P P T Sbjct: 551 PKEPAPTTPKEPAPTTPKETAP--TTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTT 603 Query: 327 EESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPE 361 + T ++ D P K + T + P PT E Sbjct: 604 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 638 Score = 35.0 bits (79), Expect = 0.29 Identities = 55/246 (22%), Positives = 87/246 (35%), Gaps = 24/246 (9%) Query: 124 TASEPEGLVMAGTASTGRRKRR----RRRKPKQKEDAVATDSSPEELEAGAESELS--LP 177 T EP TA T +K + P E T +PEEL E + P Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTP 527 Query: 178 EKLRPEPPGVQL----EEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTP 233 E+ P P +E + PK+ P + E P T+PK + ++ P Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEP 586 Query: 234 EPSPLRAESHMQWA--WGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGV 291 P+ + + + A + P ++P + +G A T+P P+TP Sbjct: 587 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTA-PTTPKEPAPTTPK------- 637 Query: 292 DPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATL 351 +P + T +P P P P T + T ++ D P K + T Sbjct: 638 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 697 Query: 352 EVPVPT 357 + P PT Sbjct: 698 KEPAPT 703 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 40.8 bits (94), Expect = 0.005 Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 18/215 (8%) Query: 150 PKQKEDAVATDSSPEELEAGAESELSLPEKLRP-EPPGVQLEEKSSLQPKDIYPYSDGEW 208 PK+ + +P + A + P P EP +E + PK + P + Sbjct: 480 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT---- 535 Query: 209 PPQASLSAGELTSPKSDSELEVRTPE-PSPLRAESHMQWAWGRLPKVARAERPESSVVLE 267 P + + + E +P + EL TPE P+P E PK A P+ Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT----PKAAAPNTPKEPAPTT 591 Query: 268 GRAGA-TSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPET 326 + A T+P P+TP + P G T +P P P P T Sbjct: 592 PKEPAPTTPKEPAPTTPKETAP--TTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTT 644 Query: 327 EESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPE 361 + T ++ D P K + T + P PT E Sbjct: 645 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 679 Score = 35.0 bits (79), Expect = 0.29 Identities = 55/246 (22%), Positives = 87/246 (35%), Gaps = 24/246 (9%) Query: 124 TASEPEGLVMAGTASTGRRKRR----RRRKPKQKEDAVATDSSPEELEAGAESELS--LP 177 T EP TA T +K + P E T +PEEL E + P Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTP 568 Query: 178 EKLRPEPPGVQL----EEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTP 233 E+ P P +E + PK+ P + E P T+PK + ++ P Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEP 627 Query: 234 EPSPLRAESHMQWA--WGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGV 291 P+ + + + A + P ++P + +G A T+P P+TP Sbjct: 628 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTA-PTTPKEPAPTTPK------- 678 Query: 292 DPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATL 351 +P + T +P P P P T + T ++ D P K + T Sbjct: 679 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 738 Query: 352 EVPVPT 357 + P PT Sbjct: 739 KEPAPT 744 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 40.8 bits (94), Expect = 0.005 Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 18/215 (8%) Query: 150 PKQKEDAVATDSSPEELEAGAESELSLPEKLRP-EPPGVQLEEKSSLQPKDIYPYSDGEW 208 PK+ + +P + A + P P EP +E + PK + P + Sbjct: 532 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT---- 587 Query: 209 PPQASLSAGELTSPKSDSELEVRTPE-PSPLRAESHMQWAWGRLPKVARAERPESSVVLE 267 P + + + E +P + EL TPE P+P E PK A P+ Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT----PKAAAPNTPKEPAPTT 643 Query: 268 GRAGA-TSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPET 326 + A T+P P+TP + P G T +P P P P T Sbjct: 644 PKEPAPTTPKEPAPTTPKETAP--TTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTT 696 Query: 327 EESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPE 361 + T ++ D P K + T + P PT E Sbjct: 697 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 731 Score = 35.0 bits (79), Expect = 0.29 Identities = 55/246 (22%), Positives = 87/246 (35%), Gaps = 24/246 (9%) Query: 124 TASEPEGLVMAGTASTGRRKRR----RRRKPKQKEDAVATDSSPEELEAGAESELS--LP 177 T EP TA T +K + P E T +PEEL E + P Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTP 620 Query: 178 EKLRPEPPGVQL----EEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTP 233 E+ P P +E + PK+ P + E P T+PK + ++ P Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEP 679 Query: 234 EPSPLRAESHMQWA--WGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGV 291 P+ + + + A + P ++P + +G A T+P P+TP Sbjct: 680 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTA-PTTPKEPAPTTPK------- 730 Query: 292 DPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATL 351 +P + T +P P P P T + T ++ D P K + T Sbjct: 731 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790 Query: 352 EVPVPT 357 + P PT Sbjct: 791 KEPAPT 796 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 40.8 bits (94), Expect = 0.005 Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 18/215 (8%) Query: 150 PKQKEDAVATDSSPEELEAGAESELSLPEKLRP-EPPGVQLEEKSSLQPKDIYPYSDGEW 208 PK+ + +P + A + P P EP +E + PK + P + Sbjct: 573 PKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT---- 628 Query: 209 PPQASLSAGELTSPKSDSELEVRTPE-PSPLRAESHMQWAWGRLPKVARAERPESSVVLE 267 P + + + E +P + EL TPE P+P E PK A P+ Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT----PKAAAPNTPKEPAPTT 684 Query: 268 GRAGA-TSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPET 326 + A T+P P+TP + P G T +P P P P T Sbjct: 685 PKEPAPTTPKEPAPTTPKETAP--TTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTT 737 Query: 327 EESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPE 361 + T ++ D P K + T + P PT E Sbjct: 738 TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE 772 Score = 35.0 bits (79), Expect = 0.29 Identities = 55/246 (22%), Positives = 87/246 (35%), Gaps = 24/246 (9%) Query: 124 TASEPEGLVMAGTASTGRRKRR----RRRKPKQKEDAVATDSSPEELEAGAESELS--LP 177 T EP TA T +K + P E T +PEEL E + P Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT--TPEELAPTTPEEPTPTTP 661 Query: 178 EKLRPEPPGVQL----EEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTP 233 E+ P P +E + PK+ P + E P T+PK + ++ P Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEP 720 Query: 234 EPSPLRAESHMQWA--WGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGV 291 P+ + + + A + P ++P + +G A T+P P+TP Sbjct: 721 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGTA-PTTPKEPAPTTPK------- 771 Query: 292 DPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATL 351 +P + T +P P P P T + T ++ D P K + T Sbjct: 772 EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831 Query: 352 EVPVPT 357 + P PT Sbjct: 832 KEPAPT 837 >gi|56676397 ankyrin repeat domain 11 [Homo sapiens] Length = 2663 Score = 40.8 bits (94), Expect = 0.005 Identities = 67/292 (22%), Positives = 108/292 (36%), Gaps = 63/292 (21%) Query: 107 PIPWGGLSGFPSDS-QLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEE 165 P+PW P D LG S PE + A+ G + E + + PEE Sbjct: 2117 PVPWADAFAGPEDDLDLGPFSLPELPLQTKDAADG-----------EAEPVEESLAPPEE 2165 Query: 166 LEAGAESELS---LPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSP 222 + GA ++ + + EPP + ++ S+ P ++ P GE P+ ++ Sbjct: 2166 MPPGAPGVINGGDVSTVVAEEPPALPPDQASTRLPAELEPEPSGE--PKLDVALEAAVEA 2223 Query: 223 KSDSELEVR-----TPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPR 277 ++ E R + EP+P+ E Q G + A AE P + A +P Sbjct: 2224 ETVPEERARGDPDSSVEPAPVPPE---QRPLGSGDQGAEAEGPPA-------ASLCAP-- 2271 Query: 278 GGPSTPSTSVAGGVDPLGLPIQQTEAG----------ADLQPDTEDPTLVGPPLHTPETE 327 GP+ + + A D G P TEA +QP+ +P P E Sbjct: 2272 DGPAPNTVAQAQAADGAG-PEDDTEASRAAAPAEGPPGGIQPEAAEPKPTAEAPKAPRVE 2330 Query: 328 E---SKTQSSGDM-------GLPPASKSWSWATLEVPVPTGQPERVSRGKGS 369 E T++ M G PP+ K + PT P ++ +GS Sbjct: 2331 EIPQRMTRNRAQMLANQSKQGPPPSEKECA--------PTPAPVTRAKARGS 2374 >gi|88196790 coiled-coil domain containing 88 [Homo sapiens] Length = 1476 Score = 40.8 bits (94), Expect = 0.005 Identities = 79/312 (25%), Positives = 114/312 (36%), Gaps = 58/312 (18%) Query: 142 RKRRRRRKPKQKEDAVATDSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIY 201 R+R R Q+E+ + + E A +S ++L E ++LE + SL+P Sbjct: 378 RERCARLHETQRENLLLR-TRLGEAHAELDSLRHQVDQLAEENVELELELQRSLEPP--- 433 Query: 202 PYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPE 261 P S GE P L + EVR E GRL + R R Sbjct: 434 PGSPGEAP---------LAGAAPSLQDEVREAEA-------------GRLRTLERENREL 471 Query: 262 SSV--VLEGRAGATSP----PRGGP------STPSTSVAGGVDPLGLPIQQTEAGA---D 306 + VL+G+ G P PR P P T VA P GL + + G D Sbjct: 472 RGLLQVLQGQPGGQHPLLEAPREDPVLPVLEEAPQTPVAFDHSPQGLVQKARDGGPQALD 531 Query: 307 LQPDTEDPTLVGP------PLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQ- 359 L P D L P P+ ES Q++ + P + WS PV T + Sbjct: 532 LAPPALDSVLEASAECPQAPDSDPQEAESPLQAAA---MDPQASDWSPQESGSPVETQES 588 Query: 360 PERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFPQSDSGLGARRWSEPSSQKSL 419 PE+ R RS P+ + P + L +++ G A + L Sbjct: 589 PEKAGR------RSSLQSPASVAPPQGPGTKIQAPQLLGGETE-GREAPQGELVPEAWGL 641 Query: 420 RDPNPEHEPEPT 431 R PEH+P P+ Sbjct: 642 RQEGPEHKPGPS 653 >gi|178557736 microtubule-associated protein tau isoform 5 [Homo sapiens] Length = 412 Score = 40.0 bits (92), Expect = 0.009 Identities = 62/245 (25%), Positives = 96/245 (39%), Gaps = 23/245 (9%) Query: 134 AGTASTGRRKRRRRRKPKQKEDAVATDSSPEELEAGA-ESELSLPEKLRPEPPGVQLEEK 192 AGT G RK + Q ++ + +AG ES L P + E PG + + Sbjct: 15 AGTYGLGDRKDQGGYTMHQDQEG--------DTDAGLKESPLQTPTEDGSEEPGSETSDA 66 Query: 193 SSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLP 252 S + G+ P +AG +T + S+ + T + + A G+ Sbjct: 67 KSTPTAEAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSD-----DKKAKGADGK-T 120 Query: 253 KVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVDP-LGLPIQQTEAGADLQPDT 311 K+A R + +G+A AT P P P T + G P G + G+ P + Sbjct: 121 KIA-TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 179 Query: 312 EDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLE-VPVPTGQPERVSRGKGSP 370 T P L TP T E K + + PP S S + + L+ PVP + V GS Sbjct: 180 RSRT---PSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 234 Query: 371 KRSQH 375 + +H Sbjct: 235 ENLKH 239 >gi|18643383 inositol 1,4,5-trisphosphate 3-kinase C [Homo sapiens] Length = 683 Score = 39.7 bits (91), Expect = 0.012 Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 9/131 (6%) Query: 123 GTASEPEGLVMAGTASTGRRKRR--RRRKPKQKEDAVATDSSPEELEAGAESELSLPEKL 180 G+ +E E + A G R RRR+P Q+ + E G + L Sbjct: 8 GSLNEAEAGALPAAARMGLEAPRGGRRRQPGQQRPGPGAGAPAGRPEGGGPWARTEGSSL 67 Query: 181 RPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRA 240 EP L + ++DG+ P A+ E PK +E P+ S LR Sbjct: 68 HSEPERAGLGPAPGTESPQAEFWTDGQTEPAAAGLGVETERPKQKTE-----PDRSSLR- 121 Query: 241 ESHMQWAWGRL 251 +H++W+W L Sbjct: 122 -THLEWSWSEL 131 >gi|71274152 hypothetical protein LOC388939 [Homo sapiens] Length = 1288 Score = 39.7 bits (91), Expect = 0.012 Identities = 70/307 (22%), Positives = 106/307 (34%), Gaps = 24/307 (7%) Query: 91 ELESDDEHVPPGLCTSPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKP 150 E+E + EH+PP + S +S T + P+ G G RR P Sbjct: 822 EMEGNLEHLPPPPMEVLMDKSFASLESPESSKSTENSPKETQEPGPGEAGPT-RRTWASP 880 Query: 151 KQKEDAVATDSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPP 210 K + D P + A L+ P P +SS QP+ P D PP Sbjct: 881 KLRASVSPLDLLPSKSTAS----LTKPHSTGPG------SGRSSCQPRK--PALDLSSPP 928 Query: 211 QASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRL-PKVARAERPESSVVLEGR 269 S SP+ + + + L + AW P + ESS+ + Sbjct: 929 ATS------QSPEVKGGTWSQAEKATSLYRQPRKAIAWHHSGPPSGQNRTSESSLARPRQ 982 Query: 270 AGATSPPRGGPSTPS-TSVAGGVDPLGLPIQQTEAGADLQPD---TEDPTLVGPPLHTPE 325 + SPP G ++P+ T D + + A P T V P + +P Sbjct: 983 SRERSPPVGRKASPTRTHWVPQADKRRRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPP 1042 Query: 326 TEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDD 385 T + +T LP + A +VP P Q S P S + PS + + Sbjct: 1043 TTKRRTSPPHQPKLPNPPPESAPAQCKVPSPPTQHPEASPPFSIPSPSPPMSPSQEHKET 1102 Query: 386 LPSLDSE 392 S DS+ Sbjct: 1103 RDSEDSQ 1109 >gi|150418009 transforming, acidic coiled-coil containing protein 2 isoform a [Homo sapiens] Length = 2948 Score = 39.3 bits (90), Expect = 0.016 Identities = 65/273 (23%), Positives = 100/273 (36%), Gaps = 40/273 (14%) Query: 180 LRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLR 239 L P PP Q E P P++ E PP+ L A +P+ + + EP+P Sbjct: 94 LLPSPPPSQERE----HPSSSMPFA--ECPPEGCL-ASPAAAPEDGPQTQSPRREPAP-N 145 Query: 240 AESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVD------- 292 A + A+ P + P + AG P+ S S + G+D Sbjct: 146 APGDIAAAF---PAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSP 202 Query: 293 -PLGLPIQQTEAGADLQP---DTEDPTLVG--PPLHTPETEESKTQSSGDMGLPPASKSW 346 PL P++ G QP ++++ G PP + + S Q + + + Sbjct: 203 VPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGVAS-VQVTPEAPAAAQQGTE 261 Query: 347 SWATLE-------VPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDDLPSLDSENAALYFP 399 S A LE P+P R S +R Q P DDL L A + P Sbjct: 262 SSAVLEKSPLKPMAPIPQDPAPRAS----DRERGQGEAPPQYLTDDLEFL----RACHLP 313 Query: 400 QSDSGLGARRWSEPSSQKSLRDPNPEHEPEPTL 432 +S+SG +SQ+S + P + P L Sbjct: 314 RSNSGAAPEAEVNAASQESCQQPVGAYLPHAEL 346 >gi|154800453 tastin isoform 1 [Homo sapiens] Length = 778 Score = 38.9 bits (89), Expect = 0.020 Identities = 49/180 (27%), Positives = 68/180 (37%), Gaps = 32/180 (17%) Query: 182 PEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSDSELEVRTPEPSPLRAE 241 PE P L+E+ + PY E P S E P+S + ++ PEP P AE Sbjct: 531 PEIPEPSLQEQLEVPE----PYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCP-PAE 585 Query: 242 SHMQWAWGRL-PKVARAERPESSVVLEGRAGATSPPRGGPSTPSTSVAGGVDPLGLPIQQ 300 ++ R+ P++ + R E V E P GP PST G P G P + Sbjct: 586 PRPLESYCRIEPEIPESSRQEQLEVPE----PCPPAEPGPLQPSTQGQSG--PPG-PCPR 638 Query: 301 TEAGADLQPDTEDPTLVGPPLHTPETEESKTQSSGDMGLPPASKSWSWATLEVPVPTGQP 360 E GA P T E ++ S LPP W+ AT + + P Sbjct: 639 VELGAS----------------EPCTLEHRSLES---SLPPCCSQWAPATTSLIFSSQHP 679 >gi|98985819 interferon regulatory factor 7 isoform d [Homo sapiens] Length = 516 Score = 38.5 bits (88), Expect = 0.027 Identities = 42/165 (25%), Positives = 62/165 (37%), Gaps = 20/165 (12%) Query: 240 AESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTP--STSVAGGVDPLGLP 297 A+ H +A R ++ E P + A PP+GGP P + + AG P LP Sbjct: 129 ADPHKVYALSR--ELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLP 186 Query: 298 IQQTEAGADLQPDTEDPTLVGPPLHTP---ETEESKTQSSGDMGLP-----------PAS 343 + G L + L L + +K G GLP PA Sbjct: 187 APAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAG 246 Query: 344 KSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDDLPS 388 + + WA P P QP ++ G+ + S H ++ YL PS Sbjct: 247 ELYGWAVETTPSPGPQPAALTTGEAAAPESPH--QAEPYLSPSPS 289 >gi|4758610 interferon regulatory factor 7 isoform a [Homo sapiens] Length = 503 Score = 38.5 bits (88), Expect = 0.027 Identities = 42/165 (25%), Positives = 62/165 (37%), Gaps = 20/165 (12%) Query: 240 AESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPSTP--STSVAGGVDPLGLP 297 A+ H +A R ++ E P + A PP+GGP P + + AG P LP Sbjct: 116 ADPHKVYALSR--ELCWREGPGTDQTEAEAPAAVPPPQGGPPGPFLAHTHAGLQAPGPLP 173 Query: 298 IQQTEAGADLQPDTEDPTLVGPPLHTP---ETEESKTQSSGDMGLP-----------PAS 343 + G L + L L + +K G GLP PA Sbjct: 174 APAGDKGDLLLQAVQQSCLADHLLTASWGADPVPTKAPGEGQEGLPLTGACAGGPGLPAG 233 Query: 344 KSWSWATLEVPVPTGQPERVSRGKGSPKRSQHLGPSDIYLDDLPS 388 + + WA P P QP ++ G+ + S H ++ YL PS Sbjct: 234 ELYGWAVETTPSPGPQPAALTTGEAAAPESPH--QAEPYLSPSPS 276 >gi|116256464 hypothetical protein LOC343990 [Homo sapiens] Length = 962 Score = 38.5 bits (88), Expect = 0.027 Identities = 75/299 (25%), Positives = 103/299 (34%), Gaps = 55/299 (18%) Query: 160 DSSPEELEAGAESEL---------SLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPP 210 D++P E + A SE S+P++ P PP + EEK P P + E P Sbjct: 410 DTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAP-EPEREAETEP 468 Query: 211 QASLSAGELTSPKSDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRA 270 + G T P+ P PSP PK RP ++ Sbjct: 469 E----RGAGTEPERIGTEPSTAPAPSP------------PAPKSCLKHRPAAA----SEG 508 Query: 271 GATSPPRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQPDTEDPTLVGPPLHTPETEESK 330 A SPP +P V+P G EA A +P E PP + Sbjct: 509 PAASPPLAAAESPP------VEP-GPGSLDAEAAAPERPKAE--RAEAPPAGAERAAPER 559 Query: 331 TQSSGDMGLPPASKSWSWATLEVPVP-TGQPERVSRGKGSPKRSQHLGPSDIYLDDLPSL 389 G L A K + P P +P + G+ RS + S+ LDDL L Sbjct: 560 KAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGL 619 Query: 390 DSENAALYFPQ-------SDSG------LGARRW-SEPSSQKSLRDPNP-EHEPEPTLD 433 A P+ DSG G R+ E ++ R+P P EP P+ D Sbjct: 620 PEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSED 678 >gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapiens] Length = 946 Score = 38.5 bits (88), Expect = 0.027 Identities = 57/213 (26%), Positives = 87/213 (40%), Gaps = 26/213 (12%) Query: 100 PPGLCTSPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVAT 159 PP SP G+ S + +S G +G++ + R R +Q+ A T Sbjct: 59 PPAESLSPEEPRSPGGWRSGRRRLNSSSGSGSGSSGSSVSSPSWAGRLRGDRQQVVAAGT 118 Query: 160 DSSPEELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGEL 219 S P EA + + L+ E VQ+ +K + I QA SA + Sbjct: 119 LSPPGPEEAKRKLRI-----LQRELQNVQVNQKVGMFEAHI----------QAQSSA--I 161 Query: 220 TSPKSDSELEVRTPEPSPLRAESHMQWAWGR-LPKVARAERPESSVVLE---GRAGATSP 275 +P+S R+P P P R+ S GR L + AR+E + E +G S Sbjct: 162 QAPRSPRLGRARSPSPCPFRSSSQPP---GRVLVQGARSEERRTKSWGEQCPETSGTDSG 218 Query: 276 PRGGPSTPSTSVAGGVDPLGLPIQQTEAGADLQ 308 +GGPS S+ V G+ P LP + G++ Q Sbjct: 219 RKGGPSLCSSQVKKGMPP--LPGRAAPTGSEAQ 249 Score = 37.4 bits (85), Expect = 0.059 Identities = 57/194 (29%), Positives = 73/194 (37%), Gaps = 24/194 (12%) Query: 106 SPIPWGGLSGFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKEDAVATDSSPEE 165 SP P PS G + V A STG P + +D T+ S Sbjct: 280 SPTPGTRSCLAPSLGLFGASLTMATEVAARVTSTG---------PHRPQDLALTEPSGRA 330 Query: 166 LEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPPQASLSAGELTSPKSD 225 E +L PE L E G L ++S P+ P DGE P + P S Sbjct: 331 REL---EDLQPPEAL-VERQGQFLGSETSPAPERGGP-RDGEPPGKMGKGYLPCGMPGSG 385 Query: 226 SELEVRTPEPSPLR---AESHMQWAWGRLPKVARAERPESSVVLEGRAGATSPPRGGPST 282 + PE + + AES +W RLP+ + PE E R+GA P GG Sbjct: 386 EPEVGKRPEETTVSVQSAESSDSLSWSRLPRALASVGPE-----EARSGA--PVGGGRWQ 438 Query: 283 PSTSVAGGVDPLGL 296 S V GG LGL Sbjct: 439 LSDRVEGGSPTLGL 452 >gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like isoform a [Homo sapiens] Length = 357 Score = 38.1 bits (87), Expect = 0.035 Identities = 45/169 (26%), Positives = 71/169 (42%), Gaps = 21/169 (12%) Query: 167 EAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWP---PQASLSAGELTSPK 223 EAG ++++ + E G L L+ K+ + D E+P P+ + ++ + PK Sbjct: 6 EAGKKTDVGVREIAEAPELGAALRH-GELELKE--EWQDEEFPRLLPEEAGTSEDPEDPK 62 Query: 224 SDSELEVRTPEPSPLRAESHMQWAWGRLPKVARAERPESSVVLEGRAG--ATSPPRGGPS 281 DS+ TP L G+ P R PE + L G SP + PS Sbjct: 63 GDSQAAAGTPSTLAL---------CGQRPMRKRLSAPELRLSLTKGPGNDGASPTQSAPS 113 Query: 282 TPSTSVAGGVDPLGLP--IQQTEAGADLQPDTEDPTLVGPPLHTPETEE 328 +P S +D L P +Q ++G + + + E P G L T ET E Sbjct: 114 SPDGSSDLEIDELETPSDSEQLDSGHEFEWEDELPRAEG--LGTSETAE 160 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.133 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,258,083 Number of Sequences: 37866 Number of extensions: 2162716 Number of successful extensions: 8801 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 370 Number of HSP's that attempted gapping in prelim test: 8162 Number of HSP's gapped (non-prelim): 1010 length of query: 851 length of database: 18,247,518 effective HSP length: 111 effective length of query: 740 effective length of database: 14,044,392 effective search space: 10392850080 effective search space used: 10392850080 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.