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Search of human proteins with 6679074
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6679074 nucleoporin like 2 [Homo sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6679074 nucleoporin like 2 [Homo sapiens] 850 0.0
gi|33946327 nucleoporin 214kDa [Homo sapiens] 52 1e-06
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 50 3e-06
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 50 4e-06
gi|89276766 trophinin isoform 5 [Homo sapiens] 49 1e-05
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 47 3e-05
gi|24430146 nucleoporin 153kDa [Homo sapiens] 47 3e-05
gi|206725452 leukocyte receptor cluster (LRC) member 9 [Homo sap... 47 3e-05
gi|56788377 nucleoporin like 1 isoform b [Homo sapiens] 46 7e-05
gi|30102928 nucleoporin like 1 isoform a [Homo sapiens] 46 7e-05
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 46 7e-05
gi|62122917 filaggrin family member 2 [Homo sapiens] 45 1e-04
gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens] 45 1e-04
gi|161016767 mucin 21 [Homo sapiens] 45 2e-04
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 44 2e-04
gi|13491166 pumilio 1 isoform 2 [Homo sapiens] 44 4e-04
gi|66932909 pumilio 1 isoform 1 [Homo sapiens] 44 4e-04
gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens] 44 4e-04
gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens] 44 4e-04
gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens] 44 4e-04
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 43 5e-04
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 43 5e-04
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 43 5e-04
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 43 5e-04
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens] 42 0.001
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 42 0.001
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 42 0.001
gi|26051237 nucleoporin 54kDa [Homo sapiens] 42 0.001
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 42 0.001
gi|67782356 corneodesmosin precursor [Homo sapiens] 42 0.001
>gi|6679074 nucleoporin like 2 [Homo sapiens]
Length = 423
Score = 850 bits (2197), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MAICQFFLQGRCRFGDRCWNEHPGARGAGGGRQQPQQQPSGNNRRGWNTTSQRYSNVIQP 60
MAICQFFLQGRCRFGDRCWNEHPGARGAGGGRQQPQQQPSGNNRRGWNTTSQRYSNVIQP
Sbjct: 1 MAICQFFLQGRCRFGDRCWNEHPGARGAGGGRQQPQQQPSGNNRRGWNTTSQRYSNVIQP 60
Query: 61 SSFSKSTPWGGSRDQEKPYFSSFDSGASTNRKEGFGLSENPFASLSPDEQKDEKKLLEGI 120
SSFSKSTPWGGSRDQEKPYFSSFDSGASTNRKEGFGLSENPFASLSPDEQKDEKKLLEGI
Sbjct: 61 SSFSKSTPWGGSRDQEKPYFSSFDSGASTNRKEGFGLSENPFASLSPDEQKDEKKLLEGI 120
Query: 121 VKDMEVWESSGQWMFSVYSPVKKKPNISGFTDISPEELRLEYHNFLTSNNLQSYLNSVQR 180
VKDMEVWESSGQWMFSVYSPVKKKPNISGFTDISPEELRLEYHNFLTSNNLQSYLNSVQR
Sbjct: 121 VKDMEVWESSGQWMFSVYSPVKKKPNISGFTDISPEELRLEYHNFLTSNNLQSYLNSVQR 180
Query: 181 LINQWRNRVNELKSLNISTKVALLSDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSS 240
LINQWRNRVNELKSLNISTKVALLSDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSS
Sbjct: 181 LINQWRNRVNELKSLNISTKVALLSDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSS 240
Query: 241 DNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAAS 300
DNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAAS
Sbjct: 241 DNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAAS 300
Query: 301 FSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPS 360
FSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPS
Sbjct: 301 FSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPS 360
Query: 361 SDTFGNSSISTSLSASSSIIATDNVLFTPRDKLTVEELEQFQSKKFTLGKIPLKPPPLEL 420
SDTFGNSSISTSLSASSSIIATDNVLFTPRDKLTVEELEQFQSKKFTLGKIPLKPPPLEL
Sbjct: 361 SDTFGNSSISTSLSASSSIIATDNVLFTPRDKLTVEELEQFQSKKFTLGKIPLKPPPLEL 420
Query: 421 LNV 423
LNV
Sbjct: 421 LNV 423
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/162 (33%), Positives = 74/162 (45%), Gaps = 29/162 (17%)
Query: 239 SSDNAQNFSFKTNSGF--AAASSGSPAGFGSSPA--FGAAAS------------TSSGIS 282
S D A F + SG + A+S + FG+S A FG AS +S G S
Sbjct: 1894 SQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGS 1953
Query: 283 TSAPAFGFGKPEVTS--AASFSFKSPAASSFGSPGFSGLP----ASLATGPVRAPVAPAF 336
++ FGF P T A+ F SP GSPGF G+P A T P+ + F
Sbjct: 1954 VASQGFGFSSPNKTGGFGAAPVFGSPPTFG-GSPGFGGVPAFGSAPAFTSPLGSTGGKVF 2012
Query: 337 GGGSSVA---GFGSPGSHSHTAF---SKPSSDTFGNSSISTS 372
G G++ A GFG S + T+F + ++ TFG+ S TS
Sbjct: 2013 GEGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTS 2054
Score = 50.4 bits (119), Expect = 3e-06
Identities = 50/165 (30%), Positives = 68/165 (41%), Gaps = 13/165 (7%)
Query: 212 NQAAPAFG-FGSSQAATFMSPGFPVNNSSSDNAQNFSFKT---NSGFAAASS-GSPAGFG 266
N A FG F SS G + S +Q F F + GF AA GSP FG
Sbjct: 1924 NSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFG 1983
Query: 267 SSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATG 326
SP FG + SAPA F P ++ + AA+S G GF + + G
Sbjct: 1984 GSPGFGGVPAFG-----SAPA--FTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFG 2036
Query: 327 PVRAPVAPAFGG-GSSVAGFGSPGSHSHTAFSKPSSDTFGNSSIS 370
+ + AP FG +GFG+ S S +FG+++ S
Sbjct: 2037 TLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNSS 2081
Score = 49.3 bits (116), Expect = 7e-06
Identities = 47/142 (33%), Positives = 63/142 (44%), Gaps = 16/142 (11%)
Query: 250 TNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAAS 309
T S AA S +GF SSPAFG A G +T A FG+ ++A+ FSF P S
Sbjct: 1693 TASTAAATPQVSSSGF-SSPAFGTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFS 1751
Query: 310 S---FGSPGFSGLPASL------ATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSK-- 358
S FG P S P S A + + +FG S G G G + AF +
Sbjct: 1752 SVPAFGQPA-SSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSP 1810
Query: 359 ---PSSDTFGNSSISTSLSASS 377
FG +S +T+ +A+S
Sbjct: 1811 GFGQGGSVFGGTSAATTTAATS 1832
Score = 48.9 bits (115), Expect = 9e-06
Identities = 59/180 (32%), Positives = 80/180 (44%), Gaps = 29/180 (16%)
Query: 205 SDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAG 264
S V G + A AFG +S ++ F P P +SSS F+ TN+ A S+
Sbjct: 1622 SIVAPGPSAEAAAFGTVTSGSSVFAQP--PAASSSSA----FNQLTNNTATAPSA----- 1670
Query: 265 FGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASS--FGSPGFSGLPAS 322
+P FG A+ ST+ FG + S AS + +P SS F SP F G A
Sbjct: 1671 ---TPVFGQVAA-----STAPSLFG---QQTGSTASTAAATPQVSSSGFSSPAF-GTTAP 1718
Query: 323 LATGPVRAPVAPAFG----GGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
G A FG +SV F PG S AF +P+S T ++S S +ASS+
Sbjct: 1719 GVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASST 1778
Score = 48.9 bits (115), Expect = 9e-06
Identities = 46/162 (28%), Positives = 65/162 (40%), Gaps = 18/162 (11%)
Query: 220 FGSSQAATF---MSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAAS 276
FG+S A TF S F + + + GF +S GFG++P FG+ +
Sbjct: 1922 FGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPT 1981
Query: 277 TSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAF 336
+P FG G P SA +F+ SP S+ G G A+ A G F
Sbjct: 1982 FGG-----SPGFG-GVPAFGSAPAFT--SPLGSTGGKVFGEGTAAASAGGF-------GF 2026
Query: 337 GGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
G S+ FG+ S + F S T G + S+ S S
Sbjct: 2027 GSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGS 2068
Score = 46.2 bits (108), Expect = 6e-05
Identities = 59/221 (26%), Positives = 88/221 (39%), Gaps = 48/221 (21%)
Query: 214 AAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNS----GFAAASSGSPAGFGSSP 269
+ PAFG +S T S SS+ ++ +FSF +S G S +PA FG SP
Sbjct: 1752 SVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPA-FGQSP 1810
Query: 270 AFGAAAS----TSSGISTSA-------PAFGFGKP-------EVTSAASFSFKSPAASSF 311
FG S TS+ +T+A A GFG + S F ++SS
Sbjct: 1811 GFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSS 1870
Query: 312 GS--------------PGFSGLPASLATGPVRAPVAPAFGGGSSVAG------FGSPGSH 351
GS G G P+ A + P + A GG S A FG+ G+
Sbjct: 1871 GSVFGSGNTGRGGGFFSGLGGKPSQDAAN--KNPFSSASGGFGSTATSNTSNLFGNSGAK 1928
Query: 352 SHTAFSKPSSDTFGNSSISTSLSASSSIIATDNVLFTPRDK 392
+ F +S +FG + + S+ +A+ F+ +K
Sbjct: 1929 TFGGF---ASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNK 1966
Score = 45.8 bits (107), Expect = 7e-05
Identities = 58/183 (31%), Positives = 78/183 (42%), Gaps = 33/183 (18%)
Query: 214 AAPAFG------FGSS---QAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAG 264
++PAFG FG + QA+ F S+S A FSF + + G PA
Sbjct: 1709 SSPAFGTTAPGVFGQTTFGQASVF-------GQSASSAASVFSFSQPGFSSVPAFGQPAS 1761
Query: 265 FG----SSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLP 320
S FGAA+STSS S F FG+ + +S A + SPGF G
Sbjct: 1762 STPTSTSGSVFGAASSTSSSSS-----FSFGQSSPNTGGGLFGQSNAPAFGQSPGF-GQG 1815
Query: 321 ASLATGPVRAPVAPAFGGGS--SVAGFGSPGSHSHTAFSKPSSD---TFGNSSISTSLSA 375
S+ G A A G S +GFGS S++ + F + +S FG S S+S S
Sbjct: 1816 GSVFGGTSAATTTAATSGFSFCQASGFGS--SNTGSVFGQAASTGGIVFGQQSSSSSGSV 1873
Query: 376 SSS 378
S
Sbjct: 1874 FGS 1876
Score = 37.7 bits (86), Expect = 0.020
Identities = 56/185 (30%), Positives = 73/185 (39%), Gaps = 43/185 (23%)
Query: 223 SQAATFMSPGFP-VNNSSSDNAQNFSFKTNSGFAAA--SSGSPAGFGSSPAFGAAASTS- 278
S AT + G P + A +FS + AA SS P +S A+++TS
Sbjct: 1564 SAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAISSAGPVAVETSSTPIASSTTSI 1623
Query: 279 --SGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPV---- 332
G S A AFG VTS +S + PAASS S F+ L + AT P PV
Sbjct: 1624 VAPGPSAEAAAFG----TVTSGSSVFAQPPAASS--SSAFNQLTNNTATAPSATPVFGQV 1677
Query: 333 ----APAFGG-------------------GSSVAGFGS--PGSHSHTAFSKPSSDTFGNS 367
AP+ G G S FG+ PG T F + S FG S
Sbjct: 1678 AASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQAS--VFGQS 1735
Query: 368 SISTS 372
+ S +
Sbjct: 1736 ASSAA 1740
Score = 32.7 bits (73), Expect = 0.64
Identities = 41/139 (29%), Positives = 58/139 (41%), Gaps = 25/139 (17%)
Query: 263 AGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAA-------------S 309
A ++PA +S ++ I+T + G P V S S S KS A S
Sbjct: 449 ASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDS 508
Query: 310 SFGSPG-----FSGLP---ASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSS 361
S +PG FS +P ASLA P +PVAP+ S FGS G + S
Sbjct: 509 SKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAASFS----FGSSGFKPTLESTPVPS 564
Query: 362 DTFGNSSISTSLSASSSII 380
+ N ++ S S+S +
Sbjct: 565 VSAPNIAMKPSFPPSTSAV 583
Score = 29.6 bits (65), Expect = 5.4
Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 6/152 (3%)
Query: 211 VNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSG-FAAASSGSPAGFGSSP 269
+N P+ G + A+ +S G + ++ S + SG F+ S SP+G G +
Sbjct: 1169 INSLKPS---GPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSGTGFN- 1224
Query: 270 AFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR 329
FG T S T+A E + +FS + S+ + S P+ + +
Sbjct: 1225 -FGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPSYEAIPESSPPSGITSASNT 1283
Query: 330 APVAPAFGGGSSVAGFGSPGSHSHTAFSKPSS 361
P PA VA G+ S + + P S
Sbjct: 1284 TPGEPAASSSRPVAPSGTALSTTSSKLETPPS 1315
>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
Length = 987
Score = 50.4 bits (119), Expect = 3e-06
Identities = 58/191 (30%), Positives = 83/191 (43%), Gaps = 37/191 (19%)
Query: 212 NQAAPAFGFGSSQA----ATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASS-GSPAGFG 266
+ AA GFGS+ A AT P +N+S+ +F G +A S S G
Sbjct: 648 SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP-----TFNIPFGSSAKSPLPSYPGAN 702
Query: 267 SSPAFGAAASTSSGISTSA--PAFG----FGKPEVTSAASFSFKSPAAS----------- 309
PAFGAA G + A P+FG FG + A+ +PA++
Sbjct: 703 PQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTP 762
Query: 310 ---SFGSPGFS--GLPASLATGPVRAPVAPAFGGGSSVAGFGSP-----GSHSHTAFSKP 359
+FG S GL A+ + A PAFGG ++V FG+ G+ + TA S
Sbjct: 763 IQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGS 822
Query: 360 SSDTFGNSSIS 370
SS FG+++ S
Sbjct: 823 SSSVFGSTTPS 833
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/127 (32%), Positives = 60/127 (47%), Gaps = 6/127 (4%)
Query: 250 TNSGFAAASSGSPA-GFGSSPAFGAAASTSSGISTSAPA-FGFGKPEVTSAASFSFKSPA 307
T++ + S+ PA GFG + ++ ST++ +T+A F FG P+ SAASF+ +
Sbjct: 557 TSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA-SAASFTPAMGS 615
Query: 308 ASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVA---GFGSPGSHSHTAFSKPSSDTF 364
FG P ++ T P A SS A GFGS + S A S + TF
Sbjct: 616 IFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTF 675
Query: 365 GNSSIST 371
N+S T
Sbjct: 676 SNTSTPT 682
Score = 42.7 bits (99), Expect = 6e-04
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 9/123 (7%)
Query: 250 TNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAAS 309
T S F A +S PA GS+ F A+TSSG + G +S++ F +P+
Sbjct: 780 TASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSG----SSSSVFGSTTPSPF 835
Query: 310 SFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSI 369
+FG S PA + + P + FG+ G TA S P + G +++
Sbjct: 836 TFGG---SAAPAGSGSFGINV-ATPGSSATTGAFSFGA-GQSGSTATSTPFTGGLGQNAL 890
Query: 370 STS 372
T+
Sbjct: 891 GTT 893
Score = 40.0 bits (92), Expect = 0.004
Identities = 44/138 (31%), Positives = 60/138 (43%), Gaps = 12/138 (8%)
Query: 256 AASSGSPAG---FGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFG 312
AASS SP F + P T G S +A A T++ + P SS G
Sbjct: 455 AASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG 514
Query: 313 SPGFSGLPASL---ATGPVRAP--VAPAFGGGSSVAGFGSP---GSHSHTAFSKPSSDTF 364
P LPA T P AP AP F G +S +P S S + SKP+ F
Sbjct: 515 PPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG-F 573
Query: 365 GNSSISTSLSASSSIIAT 382
G +S+S+S ++++ AT
Sbjct: 574 GINSVSSSSVSTTTSTAT 591
Score = 40.0 bits (92), Expect = 0.004
Identities = 48/184 (26%), Positives = 72/184 (39%), Gaps = 33/184 (17%)
Query: 210 GVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSP 269
G+ A AFG +S F S +F T+SGF A + + +G SS
Sbjct: 776 GLKATASAFGAPASSQPAF---------GGSTAVFSFGAATSSGFGATTQTASSG-SSSS 825
Query: 270 AFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR 329
FG+ + SA G G + A S + A SFG+ G SG A+
Sbjct: 826 VFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGA-GQSGSTAT------- 877
Query: 330 APVAPAFGGGSSVAGFGSPGSHSHTAF-------SKP-----SSDTFGNSSISTSLSASS 377
+ F GG G+ G + AF SKP ++ TFG ++ + + S
Sbjct: 878 ---STPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSG 934
Query: 378 SIIA 381
S ++
Sbjct: 935 SSLS 938
Score = 38.9 bits (89), Expect = 0.009
Identities = 46/159 (28%), Positives = 69/159 (43%), Gaps = 19/159 (11%)
Query: 246 FSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGI----STSAPAFGFGKPEVTSAASF 301
F +T + A ++ +P G + A A A +S S S PAFGFG V S++S
Sbjct: 525 FFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV-SSSSV 583
Query: 302 SFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGS----PGSHSHTAFS 357
S + A++ P G P + A A PA G S+ FG P + + T FS
Sbjct: 584 STTTSTATAASQPFLFGAPQASA-----ASFTPAMG---SIFQFGKPPALPTTTTVTTFS 635
Query: 358 K--PSSDTFGNSSISTSLSASSSIIATDNVLFTPRDKLT 394
+ P++ SS + S S +AT + + LT
Sbjct: 636 QSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLT 674
Score = 38.9 bits (89), Expect = 0.009
Identities = 46/152 (30%), Positives = 62/152 (40%), Gaps = 39/152 (25%)
Query: 210 GVNQAAP-------AFGFGSSQAATFMSP----GFPVNNSSSDNAQNFSFKTNSGFAAAS 258
G+N A P AF FG+ Q+ + + G N+ Q+ F N G S
Sbjct: 850 GINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTES 909
Query: 259 SGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSG 318
P FG A+ + G +T AP G TS +S SF ASS + GF G
Sbjct: 910 K---------PVFGGTATPTFGQNTPAPGVG------TSGSSLSF---GASSAPAQGFVG 951
Query: 319 LPASLATGPVRAPVAPAFGGGSSVAGFGSPGS 350
+ GP AP+F G AG +PG+
Sbjct: 952 V------GPF-GSAAPSFSIG---AGSKTPGA 973
Score = 32.0 bits (71), Expect = 1.1
Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 15/142 (10%)
Query: 257 ASSGSPAGFG-SSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPG 315
+S G PA +P F + ++ +T+AP F ++ A + SP+ S P
Sbjct: 511 SSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPA 570
Query: 316 F-------SGLPASLATGPVRAPVAP-AFGGGSSVAGFGSPGSHSHTAFSKP------SS 361
F S S T A P FG + A +P S F KP ++
Sbjct: 571 FGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTT 630
Query: 362 DTFGNSSISTSLSASSSIIATD 383
T + S+ T++ ++S A D
Sbjct: 631 VTTFSQSLPTAVPTATSSSAAD 652
>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
sapiens]
Length = 834
Score = 50.1 bits (118), Expect = 4e-06
Identities = 59/189 (31%), Positives = 80/189 (42%), Gaps = 35/189 (18%)
Query: 212 NQAAPAFGFGSSQA----ATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASS-GSPAGFG 266
+ AA GFGS+ A AT P +N+S+ +F G +A S S G
Sbjct: 497 SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP-----TFNIPFGSSAKSPLPSYPGAN 551
Query: 267 SSPAFGAAASTSSGISTSA--PAFGFGKPEVTSAASFSFKSPAASS-------------- 310
PAFGAA G + A P+FG SAA + +PA S
Sbjct: 552 PQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQ 611
Query: 311 --FGSPGFS--GLPASLATGPVRAPVAPAFGGGSSVAGFGSP-----GSHSHTAFSKPSS 361
FG S GL A+ + A PAFGG ++V FG+ G+ + TA S SS
Sbjct: 612 PTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSS 671
Query: 362 DTFGNSSIS 370
FG+++ S
Sbjct: 672 SVFGSTTPS 680
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/127 (32%), Positives = 60/127 (47%), Gaps = 6/127 (4%)
Query: 250 TNSGFAAASSGSPA-GFGSSPAFGAAASTSSGISTSAPA-FGFGKPEVTSAASFSFKSPA 307
T++ + S+ PA GFG + ++ ST++ +T+A F FG P+ SAASF+ +
Sbjct: 406 TSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA-SAASFTPAMGS 464
Query: 308 ASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVA---GFGSPGSHSHTAFSKPSSDTF 364
FG P ++ T P A SS A GFGS + S A S + TF
Sbjct: 465 IFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLTF 524
Query: 365 GNSSIST 371
N+S T
Sbjct: 525 SNTSTPT 531
Score = 42.7 bits (99), Expect = 6e-04
Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 9/123 (7%)
Query: 250 TNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAAS 309
T S F A +S PA GS+ F A+TSSG + G +S++ F +P+
Sbjct: 627 TASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSG----SSSSVFGSTTPSPF 682
Query: 310 SFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSI 369
+FG S PA + + P + FG+ G TA S P + G +++
Sbjct: 683 TFGG---SAAPAGSGSFGINV-ATPGSSATTGAFSFGA-GQSGSTATSTPFAGGLGQNAL 737
Query: 370 STS 372
T+
Sbjct: 738 GTT 740
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/138 (32%), Positives = 60/138 (43%), Gaps = 12/138 (8%)
Query: 256 AASSGSPAG---FGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFG 312
AASS SP F + P T G S SA A T++ + P SS G
Sbjct: 304 AASSASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMG 363
Query: 313 SPGFSGLPASL---ATGPVRAP--VAPAFGGGSSVAGFGSP---GSHSHTAFSKPSSDTF 364
P LPA T P AP AP F G +S +P S S + SKP+ F
Sbjct: 364 PPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFG-F 422
Query: 365 GNSSISTSLSASSSIIAT 382
G +S+S+S ++++ AT
Sbjct: 423 GINSVSSSSVSTTTSTAT 440
Score = 40.0 bits (92), Expect = 0.004
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 49/208 (23%)
Query: 210 GVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAA----ASSGSPAG- 264
G+ A AFG +S F S +F T+SGF A ASSGS +
Sbjct: 623 GLKATASAFGAPASSQPAF---------GGSTAVFSFGAATSSGFGATTQTASSGSSSSV 673
Query: 265 FGSSP----AFGAAA----STSSGISTSAP-------AFGFGKPEVTSAASFSFKSPAAS 309
FGS+ FG +A S S GI+ + P AF FG + S A+ +P A
Sbjct: 674 FGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTAT---STPFAG 730
Query: 310 SFG----------SPGFSGLPASLATGPVRAPVA-PAFGGGSSVAGFGSPGSH-SHTAFS 357
G +P + ++ + PV A P FG + G G+ GS S A S
Sbjct: 731 GLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASS 790
Query: 358 KPSSD-----TFGNSSISTSLSASSSII 380
P+ FG+++ S S+ A S +
Sbjct: 791 APAQGFVGVAPFGSAAPSFSIGAGSKTL 818
Score = 38.9 bits (89), Expect = 0.009
Identities = 46/159 (28%), Positives = 69/159 (43%), Gaps = 19/159 (11%)
Query: 246 FSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGI----STSAPAFGFGKPEVTSAASF 301
F +T + A ++ +P G + A A A +S S S PAFGFG V S++S
Sbjct: 374 FFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV-SSSSV 432
Query: 302 SFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGS----PGSHSHTAFS 357
S + A++ P G P + A A PA G S+ FG P + + T FS
Sbjct: 433 STTTSTATAASQPFLFGAPQASA-----ASFTPAMG---SIFQFGKPPALPTTTTVTTFS 484
Query: 358 K--PSSDTFGNSSISTSLSASSSIIATDNVLFTPRDKLT 394
+ P++ SS + S S +AT + + LT
Sbjct: 485 QSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTLT 523
Score = 38.5 bits (88), Expect = 0.012
Identities = 41/146 (28%), Positives = 58/146 (39%), Gaps = 34/146 (23%)
Query: 210 GVNQAAP-------AFGFGSSQAATFMSP----GFPVNNSSSDNAQNFSFKTNSGFAAAS 258
G+N A P AF FG+ Q+ + + G N+ Q+ F N G S
Sbjct: 697 GINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTES 756
Query: 259 SGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSG 318
P FG A+ + G++T AP G TS +S SF ASS + GF G
Sbjct: 757 K---------PVFGGTATPTFGLNTPAPGVG------TSGSSLSF---GASSAPAQGFVG 798
Query: 319 LPASLATGPVRAPVAPAFGGGSSVAG 344
+ + P + + G GS G
Sbjct: 799 VAPFGSAAP-----SFSIGAGSKTLG 819
>gi|89276766 trophinin isoform 5 [Homo sapiens]
Length = 1431
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/173 (34%), Positives = 78/173 (45%), Gaps = 22/173 (12%)
Query: 217 AFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAAS 276
+FG G S A F G +N S+ + SG + SSG G G+S FG
Sbjct: 1198 SFGNGLSTNAGF---GGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPG 1254
Query: 277 TSS----GISTSA-------PAFGFGKPEVTSAASFSFKSPAASSFG-----SPGFSGLP 320
TS+ G+ TSA + GFG VTS F +SFG S GFSG
Sbjct: 1255 TSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTS-DGFGGGLGTNASFGSTLGTSAGFSG-G 1312
Query: 321 ASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSL 373
S + G P A G S++ GFGS GS++ T F+ S + G SS +S+
Sbjct: 1313 LSTSDGFGSRPNASFDRGLSTIIGFGS-GSNTSTGFTGEPSTSTGFSSGPSSI 1364
Score = 48.1 bits (113), Expect = 1e-05
Identities = 56/187 (29%), Positives = 83/187 (44%), Gaps = 28/187 (14%)
Query: 194 SLNISTKVALLSDVKDGVN---QAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSF-- 248
++N S + + DG + AP+ G S P ++S N + SF
Sbjct: 720 NVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGGPGITFGVAPSTSASFSNTASISFGG 779
Query: 249 --KTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSP 306
T+S F++A+S S FG A STS+ S+ A + FG TSA SF
Sbjct: 780 TLSTSSSFSSAASIS---------FGCAHSTSTSFSSEA-SISFGGMPCTSA---SFSGG 826
Query: 307 AASSFGSPGFSGLPASLATGPVRAPVAPAFGGG-SSVAGFGSPGSHSHTAFSKPSSDTFG 365
+SSF P A+ + G + FGG S+ AGF S S + S P++ T
Sbjct: 827 VSSSFSGP--LSTSATFSGG-----ASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVF 879
Query: 366 NSSISTS 372
+S++STS
Sbjct: 880 SSALSTS 886
Score = 43.5 bits (101), Expect = 4e-04
Identities = 58/197 (29%), Positives = 83/197 (42%), Gaps = 37/197 (18%)
Query: 215 APAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFK-TNSGFAAASSGSPAGFGSSPAFGA 273
AP+ S A+ G +SS +A + SF +S + SS + FG P
Sbjct: 762 APSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPC--T 819
Query: 274 AASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFG-----SPGFSGL---PASLAT 325
+AS S G+S+S F P TSA +F A+S FG + GFSG+ S +
Sbjct: 820 SASFSGGVSSS-----FSGPLSTSA---TFSGGASSGFGGTLSTTAGFSGVLSTSTSFGS 871
Query: 326 GPVRAPV-------APAFGG--GSSVAGFGSPGSHSHTAFSKPSSDTFGNS--------- 367
P + V + FGG +SV GSP S + +S FG S
Sbjct: 872 APTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGG 931
Query: 368 SISTSLSASSSIIATDN 384
++STS+S S + N
Sbjct: 932 TLSTSVSFGGSSSTSAN 948
Score = 39.3 bits (90), Expect = 0.007
Identities = 55/207 (26%), Positives = 82/207 (39%), Gaps = 43/207 (20%)
Query: 194 SLNISTKVALLSDVKDGVNQA-APAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNS 252
+LN S + + G A + + FG + + + G P + S +A N TN+
Sbjct: 972 ALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALN----TNA 1027
Query: 253 GFAAASS----------------GSP---AGFG----SSPAFGAAASTS---SGISTSAP 286
G+ A S GSP AGFG ++ +FG A STS SG +++
Sbjct: 1028 GYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSA 1087
Query: 287 AF--------GFGKPEVTSAASFSFKSPAASSFGSP----GFSGLPASLATGPVRAPVAP 334
F GFG TSA S AA G+P GF P++ + +
Sbjct: 1088 CFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSL 1147
Query: 335 AFGGGSSVAGFGSPGSHSHTAFSKPSS 361
FGG S + S+++ F P S
Sbjct: 1148 CFGGAPSTSLCFGSASNTNLCFGGPPS 1174
Score = 36.6 bits (83), Expect = 0.044
Identities = 52/187 (27%), Positives = 74/187 (39%), Gaps = 27/187 (14%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFS------FKTNSGFAAASS------GSPAGFG 266
GFG + + T G ++S +A S T++GF S GSP+ G
Sbjct: 848 GFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSG 907
Query: 267 S-------SPAFGAAASTSSGIS-TSAPAFGFGKPEVTSAASFSFKSPAASSFGSP---- 314
S S FG + TS+G T + + FG TSA S + GSP
Sbjct: 908 SFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGA 967
Query: 315 GFSG-LPASLATGPVRAPVAPAFGGGSSV-AGFGSPGSHSHTAFSKPSSDTFGNSSISTS 372
GF G L S + G V + FGG S A FG S S P + S+++T+
Sbjct: 968 GFGGALNTSASFGSV-LNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTN 1026
Query: 373 LSASSSI 379
++
Sbjct: 1027 AGYGGAV 1033
Score = 30.4 bits (67), Expect = 3.2
Identities = 29/89 (32%), Positives = 37/89 (41%), Gaps = 18/89 (20%)
Query: 218 FGFGSSQAATFM-----SPGFPVNNSS--------SDNAQNFSFKTNSGFAAASSGSPAG 264
FG GS+ + F S GF SS S S + SGF+ S + AG
Sbjct: 1337 FGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPS-TGAG 1395
Query: 265 FGSSP----AFGAAASTSSGISTSAPAFG 289
FG P FG STS+G + A + G
Sbjct: 1396 FGGGPNTGAGFGGGPSTSAGFGSGAASLG 1424
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 47.4 bits (111), Expect = 3e-05
Identities = 56/196 (28%), Positives = 84/196 (42%), Gaps = 42/196 (21%)
Query: 212 NQAAPAFGFGSSQA----ATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASS-GSPAGFG 266
+ AA GFGS+ A AT P +N+S+ +F G +A S S G
Sbjct: 648 SSAADFSGFGSTLATSAPATSSQPTLTFSNTSTP-----TFNIPFGSSAKSPLPSYPGAN 702
Query: 267 SSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSF---KSPAASSFGSPGFSGLPASL 323
PAFGAA G + A A FG +SF+F +PAA+ +P P+ +
Sbjct: 703 PQPAFGAAEGQPPGAAKPALAPSFG-------SSFTFGNSAAPAAAPTPAP-----PSMI 750
Query: 324 ATGP--VRAPVAPAFGGG--------SSVAGFGSP-------GSHSHTAFSKPSSDTFGN 366
P V P+ P FGG ++ + FG+P G + F +S FG
Sbjct: 751 KVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFFGAATSSGFGA 810
Query: 367 SSISTSLSASSSIIAT 382
++ + S +SSS+ +
Sbjct: 811 TTQTASSGSSSSVFGS 826
Score = 42.0 bits (97), Expect = 0.001
Identities = 57/198 (28%), Positives = 84/198 (42%), Gaps = 41/198 (20%)
Query: 217 AFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAA----ASSGSPAG-FGSSP-- 269
AFG ++ A+ F +P A F T+SGF A ASSGS + FGS+
Sbjct: 772 AFGLKAT-ASAFGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPS 830
Query: 270 --AFGAAAS-----------TSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFG---- 312
FG +A+ + G ST+ AF FG + S A+ +P A G
Sbjct: 831 PFTFGGSAAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTAT---STPFAGGLGQNAL 887
Query: 313 ------SPGFSGLPASLATGPVRAPVA-PAFGGGSSVAGFGSPGSH-SHTAFSKPSSD-- 362
+P + ++ + PV A P FG + G G+ GS S A S P+
Sbjct: 888 GTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFV 947
Query: 363 ---TFGNSSISTSLSASS 377
FG++++S S+ A S
Sbjct: 948 GVAPFGSAALSFSIGAGS 965
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/146 (28%), Positives = 66/146 (45%), Gaps = 17/146 (11%)
Query: 230 SPGFPVNNSSSDNAQNFSFK-TNSGFAAASSGSPAGFGSSPA--FGAAASTSSGISTSAP 286
+P P+ ++ +A F K T S F A +S PA FG S A FGAA S+ G +T
Sbjct: 759 TPIHPIFGGATHSA--FGLKATASAFGAPASSQPA-FGGSTAVFFGAATSSGFGATTQTA 815
Query: 287 AFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFG 346
+ G +S++ F +P+ +FG S PA + + P + FG
Sbjct: 816 SSG------SSSSVFGSTTPSPFTFGG---SAAPAGSGSFGINV-ATPGSSTTTGAFSFG 865
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTS 372
+ G TA S P + G +++ T+
Sbjct: 866 A-GQSGSTATSTPFAGGLGQNALGTT 890
Score = 38.9 bits (89), Expect = 0.009
Identities = 54/197 (27%), Positives = 76/197 (38%), Gaps = 43/197 (21%)
Query: 215 APAF-GFGSSQAATF-MSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSP-AF 271
AP F G S+ +A ++ P +S+S A F + S + +++ S A S P F
Sbjct: 540 APLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLF 599
Query: 272 GAA-ASTSSGISTSAPAFGFGKPEV--------TSAASFSFKSPAASSFGSPGFSGLPAS 322
GA AS +S F FGKP T + S P A+S + FSG ++
Sbjct: 600 GAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGST 659
Query: 323 LATGPVRAPVAPA--------------FGGGSSVAGFGSPGSHSHTAF----------SK 358
LAT P FG + PG++ AF +K
Sbjct: 660 LATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAK 719
Query: 359 P-------SSDTFGNSS 368
P SS TFGNS+
Sbjct: 720 PALAPSFGSSFTFGNSA 736
Score = 38.5 bits (88), Expect = 0.012
Identities = 47/156 (30%), Positives = 67/156 (42%), Gaps = 18/156 (11%)
Query: 244 QNFSFKT-----NSGFAAASSGSPAGFG----SSPAFGAAASTSSGISTSAPAFGFGKPE 294
Q+F F T +S A A+S +P F + P T G S +A A
Sbjct: 437 QSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLP 496
Query: 295 VTSAASFSFKSPAASSFGSPGFSGLPASL---ATGPVRAPV--APAFGGGSSVAGFGSP- 348
T++ + P SS G P LPA T P AP AP F G +S +P
Sbjct: 497 TTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPI 556
Query: 349 --GSHSHTAFSKPSSDTFGNSSISTSLSASSSIIAT 382
S S + SKP+ FG +S+S+S ++++ AT
Sbjct: 557 TSASPSTDSASKPAFG-FGINSVSSSSVSTTTSTAT 591
Score = 38.5 bits (88), Expect = 0.012
Identities = 45/177 (25%), Positives = 66/177 (37%), Gaps = 39/177 (22%)
Query: 216 PAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGS-------- 267
PAFG Q P + SS F+F ++ AAA + +P
Sbjct: 705 PAFGAAEGQPPGAAKPALAPSFGSS-----FTFGNSAAPAAAPTPAPPSMIKVVPAYVPT 759
Query: 268 --SPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLAT 325
P FG A ++ G+ +A AFG +++ +F A FG+ SG A+ T
Sbjct: 760 PIHPIFGGATHSAFGLKATASAFG-----APASSQPAFGGSTAVFFGAATSSGFGATTQT 814
Query: 326 GPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSSIIAT 382
GSS + FGS + PS TFG S+ + +AT
Sbjct: 815 A----------SSGSSSSVFGS---------TTPSPFTFGGSAAPAGSGSFGINVAT 852
Score = 37.7 bits (86), Expect = 0.020
Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 18/142 (12%)
Query: 246 FSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGI----STSAPAFGFGKPEVTSAASF 301
F +T + A ++ +P G + A A A +S S S PAFGFG V S++S
Sbjct: 525 FFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV-SSSSV 583
Query: 302 SFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSS 361
S + A++ P G P + A A PA G S+ FG P A ++
Sbjct: 584 STTTSTATAASQPFLFGAPQASA-----ASFTPAMG---SIFQFGKP-----PALPTTTT 630
Query: 362 DTFGNSSISTSLSASSSIIATD 383
T + S+ T++ ++S A D
Sbjct: 631 VTTFSQSLHTAVPTATSSSAAD 652
Score = 37.7 bits (86), Expect = 0.020
Identities = 43/148 (29%), Positives = 61/148 (41%), Gaps = 31/148 (20%)
Query: 210 GVNQAAP-------AFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSP 262
G+N A P AF FG+ Q+ + + P NA + ++ SS +
Sbjct: 847 GINVATPGSSTTTGAFSFGAGQSGS-TATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTE 905
Query: 263 AGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPAS 322
S P FG A+ + G++T AP G TS +S SF ASS + GF G+
Sbjct: 906 ----SKPVFGGTATPTFGLNTPAPGVG------TSGSSLSF---GASSAPAQGFVGV--- 949
Query: 323 LATGPVRAPVAPAFGGGSSVAGFGSPGS 350
AP A S AG +PG+
Sbjct: 950 -------APFGSAALSFSIGAGSKTPGA 970
>gi|24430146 nucleoporin 153kDa [Homo sapiens]
Length = 1475
Score = 47.0 bits (110), Expect = 3e-05
Identities = 56/202 (27%), Positives = 81/202 (40%), Gaps = 39/202 (19%)
Query: 212 NQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAF 271
N F FG Q++ +S N + S +Q+ F +S A SS G +P
Sbjct: 1220 NPPVATFVFG--QSSNPVSSSAFGNTAESSTSQSLLFSQDSKLATTSS---TGTAVTPFV 1274
Query: 272 GAAASTSSGISTSAPAFGFGKPEVTSAASFSF------KSPAAS-SFGS----------- 313
++S+ +TS FGFG +S+A SF +P+AS +FG+
Sbjct: 1275 FGPGASSNNTTTS--GFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQG 1332
Query: 314 ------PGFSGLPASLATGPVRA-PVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGN 366
PGF + +S A P + P P FG SS S +PS FG+
Sbjct: 1333 ASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSS-------SSQPPVFGQQPSQSAFGS 1385
Query: 367 SSISTSLSASSSIIATDNVLFT 388
+ S SA +T N FT
Sbjct: 1386 GTTPNSSSAFQFGSSTTNFNFT 1407
Score = 33.9 bits (76), Expect = 0.29
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 24/164 (14%)
Query: 216 PAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAA 275
P F FG+S+ + +SS + +FS S S PA ++ AFGA
Sbjct: 1131 PVFSFGNSEQTK--------DENSSKSTFSFSMTKPS---EKESEQPAK--ATFAFGAQT 1177
Query: 276 STSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPA 335
ST++ + P F F + +S S +PA S+ G G G S + PV V
Sbjct: 1178 STTADQGAAKPVFSF-----LNNSSSSSSTPATSAGG--GIFGSSTSSSNPPVATFVFGQ 1230
Query: 336 FGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSSI 379
S + FG+ S + S D S ++T+ S +++
Sbjct: 1231 SSNPVSSSAFGNTAESSTSQSLLFSQD----SKLATTSSTGTAV 1270
Score = 32.7 bits (73), Expect = 0.64
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 13/162 (8%)
Query: 232 GFPVNNSSSDNAQNFSFKTNSGFAAASSGSPA--------GFGSSPAFGAAASTSSG-IS 282
GF ++SSS++A + SFK G +++SSG FG F S+ SG I+
Sbjct: 887 GFDTSSSSSNSAASSSFK--FGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSIN 944
Query: 283 TSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSV 342
+ F F KP S +S L++G F G V
Sbjct: 945 PMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFG--V 1002
Query: 343 AGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSSIIATDN 384
+ G S + +FG I+++ + +++I+ ++N
Sbjct: 1003 SNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSEN 1044
>gi|206725452 leukocyte receptor cluster (LRC) member 9 [Homo
sapiens]
Length = 501
Score = 47.0 bits (110), Expect = 3e-05
Identities = 19/33 (57%), Positives = 22/33 (66%)
Query: 4 CQFFLQGRCRFGDRCWNEHPGARGAGGGRQQPQ 36
C+FFL+GRCRFG RC HPGA G QP+
Sbjct: 46 CRFFLEGRCRFGARCRQPHPGAPAPPGREAQPE 78
>gi|56788377 nucleoporin like 1 isoform b [Homo sapiens]
Length = 587
Score = 45.8 bits (107), Expect = 7e-05
Identities = 34/111 (30%), Positives = 56/111 (50%), Gaps = 9/111 (8%)
Query: 213 QAAPAFGFGSSQAATFMSP-----GFPVNNSSSDNAQNFSFKTNSGFAAASSG-SPAGFG 266
Q PA G S +F +P G + +S ++ F T+SGF +++G S GFG
Sbjct: 461 QQQPATGPQPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCSTTGASTFGFG 520
Query: 267 SSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSF--KSPAASSFGSPG 315
++ + S G S+S F F P +T++A +F +PA++ FG+ G
Sbjct: 521 TTNKPSGSLSAGFG-SSSTSGFNFSNPGITASAGLTFGVSNPASAGFGTGG 570
Score = 41.2 bits (95), Expect = 0.002
Identities = 46/175 (26%), Positives = 75/175 (42%), Gaps = 20/175 (11%)
Query: 229 MSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPA----FGAAASTSSGISTS 284
MS GF + + + + T++G S G+ G S+P+ FG STS+ +TS
Sbjct: 1 MSTGFSFGSGTLGSTTVAAGGTSTG-GVFSFGT--GASSNPSVGLNFGNLGSTSTPATTS 57
Query: 285 APAFGFGKPEVTSAASFSFK-------SPAASSFGSPGFS---GLPASLATGPVRAPVAP 334
AP+ GFG S + F +PA +S + GFS PA+ AT P P+
Sbjct: 58 APSSGFGTGLFGSKPATGFTLGGTNTGTPATTSAATTGFSLGFNKPAASAT-PFALPITS 116
Query: 335 AFGGGSSVAG--FGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSSIIATDNVLF 387
G +++ +P + + + T ++ ST LS ++ LF
Sbjct: 117 TSASGLTLSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSLGGALAGLGGSLF 171
>gi|30102928 nucleoporin like 1 isoform a [Homo sapiens]
Length = 599
Score = 45.8 bits (107), Expect = 7e-05
Identities = 34/111 (30%), Positives = 56/111 (50%), Gaps = 9/111 (8%)
Query: 213 QAAPAFGFGSSQAATFMSP-----GFPVNNSSSDNAQNFSFKTNSGFAAASSG-SPAGFG 266
Q PA G S +F +P G + +S ++ F T+SGF +++G S GFG
Sbjct: 473 QQQPATGPQPSLGVSFGTPFGSGIGTGLQSSGLGSSNLGGFGTSSGFGCSTTGASTFGFG 532
Query: 267 SSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSF--KSPAASSFGSPG 315
++ + S G S+S F F P +T++A +F +PA++ FG+ G
Sbjct: 533 TTNKPSGSLSAGFG-SSSTSGFNFSNPGITASAGLTFGVSNPASAGFGTGG 582
Score = 38.5 bits (88), Expect = 0.012
Identities = 47/187 (25%), Positives = 76/187 (40%), Gaps = 32/187 (17%)
Query: 229 MSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPA----FGAAASTSSGISTS 284
MS GF + + + + T++G S G+ G S+P+ FG STS+ +TS
Sbjct: 1 MSTGFSFGSGTLGSTTVAAGGTSTG-GVFSFGT--GASSNPSVGLNFGNLGSTSTPATTS 57
Query: 285 APAFGFG------KP-------------EVTSAASFSFKSPAASSFGSPGFS---GLPAS 322
AP+ GFG KP T + +PA +S + GFS PA+
Sbjct: 58 APSSGFGTGLFGSKPATGFTLGGTNTGIATTITTGLTLGTPATTSAATTGFSLGFNKPAA 117
Query: 323 LATGPVRAPVAPAFGGGSSVAG--FGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSSII 380
AT P P+ G +++ +P + + + T ++ ST LS ++
Sbjct: 118 SAT-PFALPITSTSASGLTLSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSLGGALA 176
Query: 381 ATDNVLF 387
LF
Sbjct: 177 GLGGSLF 183
Score = 33.5 bits (75), Expect = 0.37
Identities = 40/194 (20%), Positives = 76/194 (39%), Gaps = 16/194 (8%)
Query: 214 AAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGA 273
+AP+ GFG+ + + GF + +++ A + G A +S + GF A
Sbjct: 57 SAPSSGFGTGLFGSKPATGFTLGGTNTGIATTITTGLTLGTPATTSAATTGFSLGFNKPA 116
Query: 274 AASTSSGIS-TSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPV 332
A++T + TS A G +T +++ + A++ F G A+ T +
Sbjct: 117 ASATPFALPITSTSASG-----LTLSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSL 171
Query: 333 APAFGG---------GSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSSIIATD 383
A G + +G G + T + ++ T GN + +SSS +D
Sbjct: 172 GGALAGLGGSLFQSTNTGTSGLGQ-NALGLTLGTTAATSTAGNEGLGGIDFSSSSDKKSD 230
Query: 384 NVLFTPRDKLTVEE 397
P D +++
Sbjct: 231 KTGTRPEDSKALKD 244
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 45.8 bits (107), Expect = 7e-05
Identities = 43/145 (29%), Positives = 64/145 (44%), Gaps = 18/145 (12%)
Query: 249 KTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAA 308
+ +SG ++ +P SS + ++AS+SS +A A G G V +A+S S +PAA
Sbjct: 116 RESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLS--TPAA 173
Query: 309 SSFGSPGF---SGLPASLAT-GPVRAP-----------VAPAFGGGSSVAGFGSPGSHSH 353
SS SP PAS++ P+ AP A S +G GS+
Sbjct: 174 SSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQ 233
Query: 354 TAFSKPSSDTFGNSSISTSLSASSS 378
+ PSS FG S+ L+ S
Sbjct: 234 -GYPTPSSSYFGGVDCSSYLAPMHS 257
Score = 30.8 bits (68), Expect = 2.4
Identities = 36/132 (27%), Positives = 58/132 (43%), Gaps = 20/132 (15%)
Query: 256 AASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPG 315
+ + PA SSP ++ S SSG F P V+S+AS S S A+SS +P
Sbjct: 101 SGTKSRPAKKKSSPVRESSGSESSG--------QFTPPAVSSSASSS--SSASSSSANPA 150
Query: 316 FSGLPASLATGPVRA------PVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSI 369
+ A L PV A P A + +S++ +P S + +P + S +
Sbjct: 151 -AAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPAS---VSVPEPLAAPSNTSCM 206
Query: 370 STSLSASSSIIA 381
S++A ++ A
Sbjct: 207 QRSVAAGAATAA 218
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 15/152 (9%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTS 278
GFG + + S GF + S S Q+ F + + SS GFGSS + G S
Sbjct: 654 GFGQYGSGSGQSSGFGQHVSGS--GQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGS 711
Query: 279 SGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGF----SGLPASLATG-----PVR 329
S TS GFG+ E++S S SF + S S GF SG S G +
Sbjct: 712 SSGQTS----GFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQ 767
Query: 330 APVAPAFGGGSSVAGFGSPGSHSHTAFSKPSS 361
+ G S +G+G GS + F + S
Sbjct: 768 SSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGS 799
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 30/164 (18%)
Query: 212 NQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPA- 270
+ + FGFG ++ + S GF + S S + F G + SG +GFG +
Sbjct: 940 SSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGF------GQHESGSGKSSGFGQHESR 993
Query: 271 --------FGAAASTSSGI----STSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGF-- 316
G+ +S SSG S+S GFG+ +S F + S S GF
Sbjct: 994 SSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQ 1053
Query: 317 ----SGLPASLATGPVRAPVAPAFG----GGSSVAGFGSPGSHS 352
SG + R+ + ++G G S +G+G GS+S
Sbjct: 1054 HGTGSGQSSGFGQYESRSRQS-SYGQHGSGSSQSSGYGQHGSNS 1096
Score = 39.7 bits (91), Expect = 0.005
Identities = 45/156 (28%), Positives = 63/156 (40%), Gaps = 28/156 (17%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFG---------SSP 269
GFG ++++ GF + S S + F G SG +GFG S
Sbjct: 870 GFGQHRSSSGQYSGFGQHGSGSGQSSGF------GQHGTGSGQYSGFGQHESRSHQSSYG 923
Query: 270 AFGAAASTSSGI----STSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGF----SGLPA 321
G+ +S SSG S+S FGFG+ S S F + S S GF SG
Sbjct: 924 QHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGK 983
Query: 322 SLATGPVRAPVAPA-FG----GGSSVAGFGSPGSHS 352
S G + + + +G G S +G+G GS S
Sbjct: 984 SSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSS 1019
Score = 39.3 bits (90), Expect = 0.007
Identities = 52/187 (27%), Positives = 74/187 (39%), Gaps = 34/187 (18%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFG---------SSP 269
GFG ++++ GF + S SD + F G SG +GFG S
Sbjct: 1024 GFGQHRSSSGQYSGFGQHGSGSDQSSGF------GQHGTGSGQSSGFGQYESRSRQSSYG 1077
Query: 270 AFGAAASTSSGI----STSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGF------SGL 319
G+ +S SSG S S GFG+ S S F + S S GF +G
Sbjct: 1078 QHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGK 1137
Query: 320 PASLATGPVRAPVAPAFG----GGSSVAGFG--SPGSHSHTAFSK--PSSDTFGNSSIST 371
+ A R+ + ++G G S +G G GS T+F + SD F +S
Sbjct: 1138 SSGFAQHEYRSGQS-SYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHI 1196
Query: 372 SLSASSS 378
S S S+
Sbjct: 1197 SDSGQST 1203
Score = 36.6 bits (83), Expect = 0.044
Identities = 44/163 (26%), Positives = 61/163 (37%), Gaps = 26/163 (15%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFG---------SSP 269
GFG + + S GF + S S + F G + SG +GFG S
Sbjct: 491 GFGQCGSGSGQSSGFGQHGSVSGQSSGF------GQHGSVSGQSSGFGQHESRSRQSSYG 544
Query: 270 AFGAAASTSSGIST--SAPAFGFGKPEVTSAASFSFKSPAASSFGSPGF----SGLPASL 323
G+ +S SSG S GFG+ + S S F + S S GF SG S
Sbjct: 545 QHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSS 604
Query: 324 ATG-----PVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSS 361
G ++ G S +G+G GS + F + S
Sbjct: 605 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGS 647
Score = 36.6 bits (83), Expect = 0.044
Identities = 40/169 (23%), Positives = 64/169 (37%), Gaps = 6/169 (3%)
Query: 210 GVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGS--PAGFGS 267
G +Q++ +GS + + F G S+ +SGF SGS +GFG
Sbjct: 549 GSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQ 608
Query: 268 SPAFGAAASTSSGISTSAPAFGFGKPEVTSAASF---SFKSPAASSFGSPGF-SGLPASL 323
+ +S S S+ + G+G+ + F S ++ FG G SG +
Sbjct: 609 HESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGF 668
Query: 324 ATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTS 372
+ + FG S +G S G H + G+SS TS
Sbjct: 669 GQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTS 717
Score = 36.2 bits (82), Expect = 0.058
Identities = 44/161 (27%), Positives = 62/161 (38%), Gaps = 30/161 (18%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFG---------SSP 269
GFG + + S GF S S + F G + SG +GFG S
Sbjct: 793 GFGQHGSGSSQSTGFGQYGSGSGQSAGF------GQHGSGSGQSSGFGQHESRSHQSSYG 846
Query: 270 AFGAAASTSSGI----STSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGF------SGL 319
G+ +S SSG S+S GFG+ +S F + S S GF SG
Sbjct: 847 QHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQ 906
Query: 320 PASLATGPVRAPVAPAFG----GGSSVAGFGSPGSHSHTAF 356
+ R+ + ++G G S +G+G GS S F
Sbjct: 907 YSGFGQHESRSHQS-SYGQHGSGSSQSSGYGQHGSSSGQTF 946
Score = 35.4 bits (80), Expect = 0.098
Identities = 44/173 (25%), Positives = 67/173 (38%), Gaps = 19/173 (10%)
Query: 219 GFGSSQAATF--------MSPGFPVNNSSSDNAQNFSFK-----TNSGFAAASSGS--PA 263
GFGSSQ++ + + GF + SS + +F +SGF SGS +
Sbjct: 697 GFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSS 756
Query: 264 GFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASF---SFKSPAASSFGSPGF-SGL 319
GFG + +S S S+ + G+G+ + F S ++ FG G SG
Sbjct: 757 GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQ 816
Query: 320 PASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTS 372
A + + FG S + S G H + G+SS TS
Sbjct: 817 SAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869
Score = 30.0 bits (66), Expect = 4.1
Identities = 35/154 (22%), Positives = 60/154 (38%), Gaps = 12/154 (7%)
Query: 236 NNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAAST--SSGISTSAPAFGFGKP 293
+ SS + + T+SG + +GS G S G +T +G +T +G+G+
Sbjct: 2181 SESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQS 2240
Query: 294 EVTSAASFSFKSPAAS--------SFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAG- 344
+ + + S S+GS SG A R P + G + G
Sbjct: 2241 TQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQ 2300
Query: 345 FGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
G H H+ + + S+ T SS ++ + SS
Sbjct: 2301 TGDTTRHGHSGYGQ-STQTGSRSSRASHFQSHSS 2333
Score = 29.3 bits (64), Expect = 7.1
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAAS-- 276
GFG + T S GF + S + T S ++ +G G + +FG S
Sbjct: 1127 GFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGS 1186
Query: 277 ---TSSG--ISTSAPAFGFGK 292
+SSG IS S + GFG+
Sbjct: 1187 DNFSSSGQHISDSGQSTGFGQ 1207
>gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]
Length = 937
Score = 45.1 bits (105), Expect = 1e-04
Identities = 61/234 (26%), Positives = 89/234 (38%), Gaps = 45/234 (19%)
Query: 194 SLNISTKVALLSDVKD--------------GVNQAAPA--FGFGSSQAATFMSPGFPVNN 237
S NISTK ++ +K+ N+ P G G++ SP
Sbjct: 179 STNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPA----- 233
Query: 238 SSSDNAQNFSFKTNSGFA-----AASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGK 292
+SS S TNSGFA A S GFG++P G + +TS + FG+
Sbjct: 234 TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNP--GGLFGQQNQQTTSLFSKPFGQ 291
Query: 293 PEVTSAASFSFKSPAASSFGSPGFSGL--------PASLATGPVRAPVAPAFGGGSSVAG 344
T FSF + + S GL P L AFG G+ + G
Sbjct: 292 ATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351
Query: 345 FGSPGSHSHTAFSKPSSDTFGNSSIST---SLSASSSIIATDNVLFTPRDKLTV 395
++T F S FGN+ ++T S +++ S T LF + LT+
Sbjct: 352 ------QTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTL 399
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 251 NSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFG---FGKPEVTSAASFSFKSPA 307
N F G GFG++ FG +T G +TS AFG FG T + ++
Sbjct: 3 NKSFGTPFGGGTGGFGTTSTFG--QNTGFG-TTSGGAFGTSAFGSSNNTGGLFGNSQTKP 59
Query: 308 ASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPG----SHSHTAFSKPSSDT 363
FG+ FS S +TG + G +++ G S G S + AF++
Sbjct: 60 GGLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTG 116
Query: 364 FGNSSISTSLSASSSIIATDNVLFTP 389
FGN STS S + T N P
Sbjct: 117 FGNFGTSTS---SGGLFGTTNTTSNP 139
Score = 42.7 bits (99), Expect = 6e-04
Identities = 35/126 (27%), Positives = 51/126 (40%), Gaps = 23/126 (18%)
Query: 214 AAPAFG------FGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGS 267
+AP+FG FG+ T ++ N NF F TN+ + PA
Sbjct: 379 SAPSFGTTSGGLFGNKPTLTL---------GTNTNTSNFGFGTNTSGNSIFGSKPAPGTL 429
Query: 268 SPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGP 327
GA T+ G A FG +P++ +FG+PGF+ A+L G
Sbjct: 430 GTGLGAGFGTALGAG-QASLFGNNQPKIGGPLG-------TGAFGAPGFNTTTATLGFGA 481
Query: 328 VRAPVA 333
+APVA
Sbjct: 482 PQAPVA 487
Score = 40.4 bits (93), Expect = 0.003
Identities = 42/127 (33%), Positives = 55/127 (43%), Gaps = 23/127 (18%)
Query: 249 KTNSGFAAASS-----GSPAGFGSS----PAFGAAASTSSGISTSAPAFGFGKPEVTSAA 299
+TN+GF A S FGSS P+FG +TS G+ + P G TS
Sbjct: 352 QTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFG---TTSGGLFGNKPTLTLGTNTNTSNF 408
Query: 300 SFSFKSPAASSFGS---PGF--SGLPASLAT--GPVRAPV----APAFGGGSSVAGFGSP 348
F + S FGS PG +GL A T G +A + P GG FG+P
Sbjct: 409 GFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP 468
Query: 349 GSHSHTA 355
G ++ TA
Sbjct: 469 GFNTTTA 475
Score = 34.3 bits (77), Expect = 0.22
Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 238 SSSDNAQNFSFKTNSG-----FAAASSGSPAG-FGSSPA-----FGAAASTSSGISTSAP 286
++S QN F T SG A SS + G FG+S FG ++ + STS
Sbjct: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST- 77
Query: 287 AFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFG 346
FGFG T+ F S S F S + + TG FG +S G
Sbjct: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQN-NAFAQNKPTG------FGNFGTSTSSGGLF 130
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTS 372
+ + F S FG SS + +
Sbjct: 131 GTTNTTSNPFGSTSGSLFGPSSFTAA 156
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 24/116 (20%)
Query: 205 SDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAG 264
S + FGFG+S G +S ++QN +F N P G
Sbjct: 66 SSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQN---------KPTG 116
Query: 265 FGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLP 320
FG+ FG STSSG G T+ S F S + S FG F+ P
Sbjct: 117 FGN---FG--TSTSSG----------GLFGTTNTTSNPFGSTSGSLFGPSSFTAAP 157
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 44.7 bits (104), Expect = 2e-04
Identities = 53/229 (23%), Positives = 91/229 (39%), Gaps = 18/229 (7%)
Query: 167 TSNNLQSYLNSVQRLINQWRNRVNELKSLNISTKVALLSDVKDGVNQAAPAFGFGSSQAA 226
TS+ + NS R + +S S+ + ++ + + S +
Sbjct: 203 TSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESST 262
Query: 227 TFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAP 286
T G N+ SS + S TNS + SSG+ S +++TSSG +T+
Sbjct: 263 TSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSE-----SSTTSSGANTATN 317
Query: 287 AFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFG 346
+ S+ + S S A +S S SG AS AT + + G S+ G
Sbjct: 318 S--------DSSTTSSGASTATNSESSTTSSG--ASTATNSESSTTS---SGASTATNSG 364
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTSLSASSSIIATDNVLFTPRDKLTV 395
S + S T+ + S + +S ST+ ++ SS ++ T + TV
Sbjct: 365 SSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTV 413
Score = 37.0 bits (84), Expect = 0.034
Identities = 50/213 (23%), Positives = 87/213 (40%), Gaps = 23/213 (10%)
Query: 167 TSNNLQSYLNSVQRLINQWRNRVNELKSLNISTKVALLSDVKDGVNQAAPAFGFGSSQAA 226
TS+ + NS ++ + V +S S+ ++ + + S +
Sbjct: 263 TSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSST 322
Query: 227 TFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAP 286
T N+ SS + S TNS + SSG+ S+ +++TSSG ST+
Sbjct: 323 TSSGASTATNSESSTTSSGASTATNSESSTTSSGA-----STATNSGSSTTSSGTSTATN 377
Query: 287 AFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFG 346
+ S+ S S A +S S SG AS AT + V+ G+S A
Sbjct: 378 S--------ESSTVSSGASTATTSESSTTSSG--ASTATNSESSTVS----SGASTA--- 420
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTSLSASSSI 379
S S T S ++ T SS++++ S ++++
Sbjct: 421 -TNSESSTTSSGANTATNSGSSVTSAGSGTAAL 452
Score = 36.6 bits (83), Expect = 0.044
Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 12/158 (7%)
Query: 222 SSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSG-SPAGFGSSPAFGAAASTSSG 280
S + T N+ + S TNS F+ SSG S A S + AST++
Sbjct: 63 SGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATN 122
Query: 281 ISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGS 340
+S P+ G T+ S S + + +S + S +S A+ + + G S
Sbjct: 123 SESSTPSSGAS----TATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGAS 178
Query: 341 SVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
+ + S S T S+ S+ T NS ST+ S +S+
Sbjct: 179 T-----ATNSESSTVSSRASTAT--NSESSTTSSGAST 209
Score = 36.6 bits (83), Expect = 0.044
Identities = 47/219 (21%), Positives = 86/219 (39%), Gaps = 7/219 (3%)
Query: 161 EYHNFLTSNNLQSYLNSVQRLINQWRNRVNELKSLNISTKVALLSDVKDGVNQAAPAFGF 220
E+H TS+ + + NS ++ + +S S+ + ++ + + +
Sbjct: 79 EFHT--TSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTAT 136
Query: 221 GSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSG-SPAGFGSSPAFGAAASTSS 279
S + T N+ SS + S TNS + SSG S A S + AST++
Sbjct: 137 NSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTAT 196
Query: 280 GISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGG 339
+S + G T++ S + + A ++ S S + +T P+ G G
Sbjct: 197 NSESSTTS--SGASTATNSESRTTSNGAGTATNSES-STTSSGASTATNSESSTPSSGAG 253
Query: 340 SSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
++ S S + S T +S IST ++ SS
Sbjct: 254 TATNSESSTTSSGAGTATNSESSTV-SSGISTVTNSESS 291
Score = 33.9 bits (76), Expect = 0.29
Identities = 33/151 (21%), Positives = 66/151 (43%), Gaps = 9/151 (5%)
Query: 232 GFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGIST---SAPAF 288
G ++ ++ N+ S N+G + SSG+ S+ ++ TSSG+ST S +
Sbjct: 13 GLLLHLEAATNSNETSTSANTGSSVISSGA-----STATNSGSSVTSSGVSTATISGSSV 67
Query: 289 GFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGS- 347
+ + + F S S+ + FS + + ++ + G ++ S
Sbjct: 68 TSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESST 127
Query: 348 PGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
P S + TA + SS T +S +T+ +S++
Sbjct: 128 PSSGASTATNSDSSTTSSGASTATNSDSSTT 158
Score = 30.8 bits (68), Expect = 2.4
Identities = 54/304 (17%), Positives = 93/304 (30%), Gaps = 26/304 (8%)
Query: 20 NEHPGARGAGGGRQQPQQQPSGNNRRGWNTTSQRY---SNVIQPSSFSKSTPWGGSRDQE 76
N +G + + +N G T S+ S ++ STP G+
Sbjct: 197 NSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTAT 256
Query: 77 KPYFSSFDSGASTNRKEGFGLSENPFASLSPDEQKDEKKLLEGIVKDMEVWESSGQWMFS 136
S+ SGA T + ++++ E SSG
Sbjct: 257 NSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSG----- 311
Query: 137 VYSPVKKKPNISGFTDISPEELRLEYHNFLTSNNLQSYLNSVQRLINQWRNRVNELKSLN 196
N T S + TS+ + NS + + S
Sbjct: 312 ----ANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSST 367
Query: 197 ISTKVALLSDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAA 256
S+ + ++ + + + S + T N+ SS + S TNS +
Sbjct: 368 TSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESST 427
Query: 257 ASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGF 316
SSG A+T++ +S + G G +T + S + A S PG
Sbjct: 428 TSSG--------------ANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGG 473
Query: 317 SGLP 320
S +P
Sbjct: 474 SLVP 477
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/155 (27%), Positives = 75/155 (48%), Gaps = 21/155 (13%)
Query: 239 SSDNAQNFSFKTNSGFAAASSG-----SPAGFGSSPAFGAAASTSSGISTSAPAF----- 288
+S +A S +NSG+A+ S+ S +G+ S A GA+ ++SG ++ + ++
Sbjct: 21 ASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPS 80
Query: 289 --GFGKPEVTSAASFS---FKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVA 343
G+ P + A++ S + SP+AS P SG + +G A + AF S +
Sbjct: 81 DSGWASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSG---ASIPSAFWASPSAS 137
Query: 344 GFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
G +P S + ++ PS+ SS S S S+S
Sbjct: 138 GASTP---SDSGWASPSASWASTSSDSGWASPSAS 169
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 9/131 (6%)
Query: 216 PAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAA-----ASSGSPAGFGSSPA 270
P+ + SS A+ +P + SSS + S + SG+A+ AS+ S +G+ S A
Sbjct: 290 PSASWASSSASWASAPSD--SGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSA 347
Query: 271 FGAAASTSSG-ISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR 329
G + ++ SG S SA ++ S S+ SP+AS +P SG + A+G
Sbjct: 348 SGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASG-AS 406
Query: 330 APVAPAFGGGS 340
P AP+ GS
Sbjct: 407 MPSAPSLCPGS 417
Score = 39.3 bits (90), Expect = 0.007
Identities = 52/183 (28%), Positives = 88/183 (48%), Gaps = 26/183 (14%)
Query: 214 AAPAFGFGSSQAATFMSPGFPVNNSSSDN------AQNFSFKTNSGFAAASSGSPAGFGS 267
A+P+ S +A + SP ++ SD+ A S ++SG+A SP+ +
Sbjct: 117 ASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWA-----SPSASWT 171
Query: 268 SPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSP---GFSGLPASLA 324
SP+ A+S++SG ST + + G+ P V + SP+ S SP G++ P+
Sbjct: 172 SPSASCASSSASGASTPSDS-GWASPSVF------WVSPSTSWASSPSDFGWASTPSDSG 224
Query: 325 TGPVRAP-VAPAFGGG--SSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSSIIA 381
A ++P+ G SS +G+ SP S S + S + T +S ++S SAS I
Sbjct: 225 WASSSASCISPSASGASTSSDSGWASP-SASWVSTSTSRASTSSDSGWASS-SASWDSIT 282
Query: 382 TDN 384
+D+
Sbjct: 283 SDS 285
Score = 38.9 bits (89), Expect = 0.009
Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 9/147 (6%)
Query: 239 SSDNAQNFSFKTNSGFAAAS-SGS--PAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEV 295
+S +A S ++SG+A+ S SG+ P+ F +SP+ + AST S ++P+ +
Sbjct: 101 ASPSASGASIPSDSGWASPSVSGASIPSAFWASPS-ASGASTPSDSGWASPSASWASTSS 159
Query: 296 TS---AASFSFKSPAAS--SFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGS 350
S + S S+ SP+AS S + G S S P V+P+ SS + FG +
Sbjct: 160 DSGWASPSASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWAST 219
Query: 351 HSHTAFSKPSSDTFGNSSISTSLSASS 377
S + ++ S+ S+ S S+ S
Sbjct: 220 PSDSGWASSSASCISPSASGASTSSDS 246
Score = 35.0 bits (79), Expect = 0.13
Identities = 49/175 (28%), Positives = 75/175 (42%), Gaps = 37/175 (21%)
Query: 245 NFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGIST---------------SAPAFG 289
+F F SG S+ S +G+ SS A GA+ ++SG ++ S A G
Sbjct: 3 SFLFSRASG---VSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASG 59
Query: 290 FGKPEVTSAASFS-----------FKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGG 338
P + ASFS + SP+AS +P SG + A+G A + G
Sbjct: 60 ASTPSNSGWASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASG---ASIPSDSGW 116
Query: 339 GS-SVAGFGSP----GSHSHTAFSKPSSDTFGNSSISTSLSASSSIIATDNVLFT 388
S SV+G P S S + S PS + + S S + ++S S A+ + +T
Sbjct: 117 ASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWT 171
Score = 33.5 bits (75), Expect = 0.37
Identities = 44/185 (23%), Positives = 82/185 (44%), Gaps = 8/185 (4%)
Query: 197 ISTKVALLSDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDN--AQNFSFKTNSGF 254
+S + S D + P+ +S +A+ +SP ++SSD+ A + ++
Sbjct: 201 VSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTST 260
Query: 255 AAASSGSPAGFGSSPAFGAAASTSSG-ISTSAPAFGFGKPEVTSAASFSFKSPAASSFGS 313
+ AS+ S +G+ SS A + ++ SG + SA ++ + SP+ S +
Sbjct: 261 SRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRAST 320
Query: 314 PGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSL 373
SG + A+G AP+ G +S + G + S + ++ PS+ SS S
Sbjct: 321 LSVSGWASFSASG----ASAPSDSGWTSHSASG-VSTTSDSGWASPSASGASTSSDSGWA 375
Query: 374 SASSS 378
S S+S
Sbjct: 376 SPSAS 380
Score = 30.0 bits (66), Expect = 4.1
Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 20/165 (12%)
Query: 222 SSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSG--SPA-GFGSSPAFGAAASTS 278
+S +A++ SP +SS+ A S ++SG+A+ S SP+ + SSP+ AST
Sbjct: 164 ASPSASWTSPSASCASSSASGA---STPSDSGWASPSVFWVSPSTSWASSPSDFGWASTP 220
Query: 279 SGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPAS-LATGPVRAPVAPAFG 337
S ++ +SA+ S + AS+ G++ AS ++T RA + G
Sbjct: 221 SDSGWAS----------SSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSG 270
Query: 338 GGSSVAGFGSPGSHSH---TAFSKPSSDTFGNSSISTSLSASSSI 379
SS A + S S S + S SS S+ S S S+S S+
Sbjct: 271 WASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSV 315
>gi|13491166 pumilio 1 isoform 2 [Homo sapiens]
Length = 1186
Score = 43.5 bits (101), Expect = 4e-04
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 19/175 (10%)
Query: 230 SPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSG-----ISTS 284
S F NNS + N+Q+ S + +A + + GFGSS + GA ++ G ++ S
Sbjct: 642 SSSFYGNNSLNSNSQSSSLFSQG--SAQPANTSLGFGSSSSLGATLGSALGGFGTAVANS 699
Query: 285 APAFGFGKPEVTSAAS-FSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVA 343
G + +T ++ + S + + G ++GL S + GPV P+ P+ G G S
Sbjct: 700 NTGSGSRRDSLTGSSDLYKRTSSSLTPIGHSFYNGLSFSSSPGPVGMPL-PSQGPGHSQT 758
Query: 344 GFGSPGSHSHTAFSKPSSDTFGNSSIST----------SLSASSSIIATDNVLFT 388
S SH ++ T G+ + S S++SS+ + + LF+
Sbjct: 759 PPPSLSSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFS 813
>gi|66932909 pumilio 1 isoform 1 [Homo sapiens]
Length = 1188
Score = 43.5 bits (101), Expect = 4e-04
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 19/175 (10%)
Query: 230 SPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSG-----ISTS 284
S F NNS + N+Q+ S + +A + + GFGSS + GA ++ G ++ S
Sbjct: 642 SSSFYGNNSLNSNSQSSSLFSQG--SAQPANTSLGFGSSSSLGATLGSALGGFGTAVANS 699
Query: 285 APAFGFGKPEVTSAAS-FSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVA 343
G + +T ++ + S + + G ++GL S + GPV P+ P+ G G S
Sbjct: 700 NTGSGSRRDSLTGSSDLYKRTSSSLTPIGHSFYNGLSFSSSPGPVGMPL-PSQGPGHSQT 758
Query: 344 GFGSPGSHSHTAFSKPSSDTFGNSSIST----------SLSASSSIIATDNVLFT 388
S SH ++ T G+ + S S++SS+ + + LF+
Sbjct: 759 PPPSLSSHGSSSSLNLGGLTNGSGRYISAAPGAEAKYRSASSASSLFSPSSTLFS 813
>gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]
Length = 1726
Score = 43.5 bits (101), Expect = 4e-04
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 42/214 (19%)
Query: 194 SLNISTKVALLSDVKD--------------GVNQAAPA--FGFGSSQAATFMSPGFPVNN 237
S NISTK ++ +K+ N+ P G G++ SP
Sbjct: 179 STNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPA----- 233
Query: 238 SSSDNAQNFSFKTNSGFA-----AASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGK 292
+SS S TNSGFA A S GFG++P G + +TS + FG+
Sbjct: 234 TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNP--GGLFGQQNQQTTSLFSKPFGQ 291
Query: 293 PEVTSAASFSFKSPAASSFGSPGFSGL--------PASLATGPVRAPVAPAFGGGSSVAG 344
T FSF + + S GL P L AFG G+ + G
Sbjct: 292 ATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351
Query: 345 FGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
++T F S FGN+ ++T S+++S
Sbjct: 352 ------QTNTGFGAVGSTLFGNNKLTTFGSSTTS 379
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 251 NSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFG---FGKPEVTSAASFSFKSPA 307
N F G GFG++ FG +T G +TS AFG FG T + ++
Sbjct: 3 NKSFGTPFGGGTGGFGTTSTFG--QNTGFG-TTSGGAFGTSAFGSSNNTGGLFGNSQTKP 59
Query: 308 ASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPG----SHSHTAFSKPSSDT 363
FG+ FS S +TG + G +++ G S G S + AF++
Sbjct: 60 GGLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTG 116
Query: 364 FGNSSISTSLSASSSIIATDNVLFTP 389
FGN STS S + T N P
Sbjct: 117 FGNFGTSTS---SGGLFGTTNTTSNP 139
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 18/124 (14%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNS--GFAAASSGSPAGFGSSPA------ 270
GFG+ + F + SS+ +A +F + GF +SG+ FGS PA
Sbjct: 356 GFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI-FGSKPAPGTLGT 414
Query: 271 -FGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR 329
GA T+ G A FG +P++ +FG+PGF+ A+L G +
Sbjct: 415 GLGAGFGTALGAG-QASLFGNNQPKIGGPLG-------TGAFGAPGFNTTTATLGFGAPQ 466
Query: 330 APVA 333
APVA
Sbjct: 467 APVA 470
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/147 (29%), Positives = 66/147 (44%), Gaps = 18/147 (12%)
Query: 220 FGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGS--SPAFGAAAST 277
FG +QA+ PG + ++++ + +F T +G ++ GFG+ S FG T
Sbjct: 319 FGVTQAS---QPG-GLFGTATNTSTGTAFGTGTGLFGQTN---TGFGAVGSTLFGNNKLT 371
Query: 278 SSGIST-SAPAFG------FGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR- 329
+ G ST SAP+FG FG TS S PA + G+ +G +L G
Sbjct: 372 TFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASL 431
Query: 330 -APVAPAFGGGSSVAGFGSPGSHSHTA 355
P GG FG+PG ++ TA
Sbjct: 432 FGNNQPKIGGPLGTGAFGAPGFNTTTA 458
Score = 34.3 bits (77), Expect = 0.22
Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 238 SSSDNAQNFSFKTNSG-----FAAASSGSPAG-FGSSPA-----FGAAASTSSGISTSAP 286
++S QN F T SG A SS + G FG+S FG ++ + STS
Sbjct: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST- 77
Query: 287 AFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFG 346
FGFG T+ F S S F S + + TG FG +S G
Sbjct: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQN-NAFAQNKPTG------FGNFGTSTSSGGLF 130
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTS 372
+ + F S FG SS + +
Sbjct: 131 GTTNTTSNPFGSTSGSLFGPSSFTAA 156
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 24/116 (20%)
Query: 205 SDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAG 264
S + FGFG+S G +S ++QN +F N P G
Sbjct: 66 SSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQN---------KPTG 116
Query: 265 FGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLP 320
FG+ FG STSSG G T+ S F S + S FG F+ P
Sbjct: 117 FGN---FG--TSTSSG----------GLFGTTNTTSNPFGSTSGSLFGPSSFTAAP 157
>gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]
Length = 1800
Score = 43.5 bits (101), Expect = 4e-04
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 42/214 (19%)
Query: 194 SLNISTKVALLSDVKD--------------GVNQAAPA--FGFGSSQAATFMSPGFPVNN 237
S NISTK ++ +K+ N+ P G G++ SP
Sbjct: 179 STNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPA----- 233
Query: 238 SSSDNAQNFSFKTNSGFA-----AASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGK 292
+SS S TNSGFA A S GFG++P G + +TS + FG+
Sbjct: 234 TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNP--GGLFGQQNQQTTSLFSKPFGQ 291
Query: 293 PEVTSAASFSFKSPAASSFGSPGFSGL--------PASLATGPVRAPVAPAFGGGSSVAG 344
T FSF + + S GL P L AFG G+ + G
Sbjct: 292 ATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351
Query: 345 FGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
++T F S FGN+ ++T S+++S
Sbjct: 352 ------QTNTGFGAVGSTLFGNNKLTTFGSSTTS 379
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 251 NSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFG---FGKPEVTSAASFSFKSPA 307
N F G GFG++ FG +T G +TS AFG FG T + ++
Sbjct: 3 NKSFGTPFGGGTGGFGTTSTFG--QNTGFG-TTSGGAFGTSAFGSSNNTGGLFGNSQTKP 59
Query: 308 ASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPG----SHSHTAFSKPSSDT 363
FG+ FS S +TG + G +++ G S G S + AF++
Sbjct: 60 GGLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTG 116
Query: 364 FGNSSISTSLSASSSIIATDNVLFTP 389
FGN STS S + T N P
Sbjct: 117 FGNFGTSTS---SGGLFGTTNTTSNP 139
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 18/124 (14%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNS--GFAAASSGSPAGFGSSPA------ 270
GFG+ + F + SS+ +A +F + GF +SG+ FGS PA
Sbjct: 356 GFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI-FGSKPAPGTLGT 414
Query: 271 -FGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR 329
GA T+ G A FG +P++ +FG+PGF+ A+L G +
Sbjct: 415 GLGAGFGTALGAG-QASLFGNNQPKIGGPLG-------TGAFGAPGFNTTTATLGFGAPQ 466
Query: 330 APVA 333
APVA
Sbjct: 467 APVA 470
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/147 (29%), Positives = 66/147 (44%), Gaps = 18/147 (12%)
Query: 220 FGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGS--SPAFGAAAST 277
FG +QA+ PG + ++++ + +F T +G ++ GFG+ S FG T
Sbjct: 319 FGVTQAS---QPG-GLFGTATNTSTGTAFGTGTGLFGQTN---TGFGAVGSTLFGNNKLT 371
Query: 278 SSGIST-SAPAFG------FGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR- 329
+ G ST SAP+FG FG TS S PA + G+ +G +L G
Sbjct: 372 TFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASL 431
Query: 330 -APVAPAFGGGSSVAGFGSPGSHSHTA 355
P GG FG+PG ++ TA
Sbjct: 432 FGNNQPKIGGPLGTGAFGAPGFNTTTA 458
Score = 34.3 bits (77), Expect = 0.22
Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 238 SSSDNAQNFSFKTNSG-----FAAASSGSPAG-FGSSPA-----FGAAASTSSGISTSAP 286
++S QN F T SG A SS + G FG+S FG ++ + STS
Sbjct: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST- 77
Query: 287 AFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFG 346
FGFG T+ F S S F S + + TG FG +S G
Sbjct: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQN-NAFAQNKPTG------FGNFGTSTSSGGLF 130
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTS 372
+ + F S FG SS + +
Sbjct: 131 GTTNTTSNPFGSTSGSLFGPSSFTAA 156
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 24/116 (20%)
Query: 205 SDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAG 264
S + FGFG+S G +S ++QN +F N P G
Sbjct: 66 SSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQN---------KPTG 116
Query: 265 FGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLP 320
FG+ FG STSSG G T+ S F S + S FG F+ P
Sbjct: 117 FGN---FG--TSTSSG----------GLFGTTNTTSNPFGSTSGSLFGPSSFTAAP 157
>gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens]
Length = 920
Score = 43.5 bits (101), Expect = 4e-04
Identities = 56/214 (26%), Positives = 82/214 (38%), Gaps = 42/214 (19%)
Query: 194 SLNISTKVALLSDVKD--------------GVNQAAPA--FGFGSSQAATFMSPGFPVNN 237
S NISTK ++ +K+ N+ P G G++ SP
Sbjct: 179 STNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPA----- 233
Query: 238 SSSDNAQNFSFKTNSGFA-----AASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGK 292
+SS S TNSGFA A S GFG++P G + +TS + FG+
Sbjct: 234 TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNP--GGLFGQQNQQTTSLFSKPFGQ 291
Query: 293 PEVTSAASFSFKSPAASSFGSPGFSGL--------PASLATGPVRAPVAPAFGGGSSVAG 344
T FSF + + S GL P L AFG G+ + G
Sbjct: 292 ATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351
Query: 345 FGSPGSHSHTAFSKPSSDTFGNSSISTSLSASSS 378
++T F S FGN+ ++T S+++S
Sbjct: 352 ------QTNTGFGAVGSTLFGNNKLTTFGSSTTS 379
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/146 (28%), Positives = 59/146 (40%), Gaps = 16/146 (10%)
Query: 251 NSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFG---FGKPEVTSAASFSFKSPA 307
N F G GFG++ FG +T G +TS AFG FG T + ++
Sbjct: 3 NKSFGTPFGGGTGGFGTTSTFG--QNTGFG-TTSGGAFGTSAFGSSNNTGGLFGNSQTKP 59
Query: 308 ASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPG----SHSHTAFSKPSSDT 363
FG+ FS S +TG + G +++ G S G S + AF++
Sbjct: 60 GGLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTG 116
Query: 364 FGNSSISTSLSASSSIIATDNVLFTP 389
FGN STS S + T N P
Sbjct: 117 FGNFGTSTS---SGGLFGTTNTTSNP 139
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/124 (29%), Positives = 55/124 (44%), Gaps = 18/124 (14%)
Query: 219 GFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNS--GFAAASSGSPAGFGSSPA------ 270
GFG+ + F + SS+ +A +F + GF +SG+ FGS PA
Sbjct: 356 GFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI-FGSKPAPGTLGT 414
Query: 271 -FGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR 329
GA T+ G A FG +P++ +FG+PGF+ A+L G +
Sbjct: 415 GLGAGFGTALGAG-QASLFGNNQPKIGGPLG-------TGAFGAPGFNTTTATLGFGAPQ 466
Query: 330 APVA 333
APVA
Sbjct: 467 APVA 470
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/147 (29%), Positives = 66/147 (44%), Gaps = 18/147 (12%)
Query: 220 FGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGS--SPAFGAAAST 277
FG +QA+ PG + ++++ + +F T +G ++ GFG+ S FG T
Sbjct: 319 FGVTQAS---QPG-GLFGTATNTSTGTAFGTGTGLFGQTN---TGFGAVGSTLFGNNKLT 371
Query: 278 SSGIST-SAPAFG------FGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVR- 329
+ G ST SAP+FG FG TS S PA + G+ +G +L G
Sbjct: 372 TFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASL 431
Query: 330 -APVAPAFGGGSSVAGFGSPGSHSHTA 355
P GG FG+PG ++ TA
Sbjct: 432 FGNNQPKIGGPLGTGAFGAPGFNTTTA 458
Score = 34.3 bits (77), Expect = 0.22
Identities = 41/146 (28%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 238 SSSDNAQNFSFKTNSG-----FAAASSGSPAG-FGSSPA-----FGAAASTSSGISTSAP 286
++S QN F T SG A SS + G FG+S FG ++ + STS
Sbjct: 19 TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST- 77
Query: 287 AFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFG 346
FGFG T+ F S S F S + + TG FG +S G
Sbjct: 78 GFGFGTSTGTANTLFGTASTGTSLFSSQN-NAFAQNKPTG------FGNFGTSTSSGGLF 130
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTS 372
+ + F S FG SS + +
Sbjct: 131 GTTNTTSNPFGSTSGSLFGPSSFTAA 156
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 24/116 (20%)
Query: 205 SDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAG 264
S + FGFG+S G +S ++QN +F N P G
Sbjct: 66 SSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQN---------KPTG 116
Query: 265 FGSSPAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLP 320
FG+ FG STSSG G T+ S F S + S FG F+ P
Sbjct: 117 FGN---FG--TSTSSG----------GLFGTTNTTSNPFGSTSGSLFGPSSFTAAP 157
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 43.1 bits (100), Expect = 5e-04
Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 4/148 (2%)
Query: 232 GFPVNNSSSDNAQNFS-FKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGF 290
G P +N + + + F + G G+P G G+ G +++ + +
Sbjct: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
Query: 291 GKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGS 350
G+ +F + A + PG+ + AS P GGGSS +G GS GS
Sbjct: 194 GQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS-GS 250
Query: 351 HSHTAFSKPSSDTFGNSSISTSLSASSS 378
S ++ S + D SS S S SSS
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
Score = 30.0 bits (66), Expect = 4.1
Identities = 32/128 (25%), Positives = 51/128 (39%), Gaps = 21/128 (16%)
Query: 210 GVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDN--------AQNFSFKTNSGFAAASSGS 261
G N P FG + A PG+ +S+ N + + +NSG + S
Sbjct: 196 GGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
Query: 262 PAGFGSS-----------PAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASS 310
+G GS+ + G+++ SSG S+ + G S + S+ S SS
Sbjct: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
Query: 311 FGSPGFSG 318
G+ G SG
Sbjct: 314 SGNHGGSG 321
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 43.1 bits (100), Expect = 5e-04
Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 4/148 (2%)
Query: 232 GFPVNNSSSDNAQNFS-FKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGF 290
G P +N + + + F + G G+P G G+ G +++ + +
Sbjct: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
Query: 291 GKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGS 350
G+ +F + A + PG+ + AS P GGGSS +G GS GS
Sbjct: 194 GQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS-GS 250
Query: 351 HSHTAFSKPSSDTFGNSSISTSLSASSS 378
S ++ S + D SS S S SSS
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
Score = 34.7 bits (78), Expect = 0.17
Identities = 44/195 (22%), Positives = 71/195 (36%), Gaps = 21/195 (10%)
Query: 210 GVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDN--------AQNFSFKTNSGFAAASSGS 261
G N P FG + A PG+ +S+ N + + +NSG + S
Sbjct: 196 GGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
Query: 262 PAGFGSS-----------PAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASS 310
+G GS+ + G+++ SSG S+ + G S + S+ S SS
Sbjct: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
Query: 311 FGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSIS 370
G+ G SG G + G S + GF G S+ S+ S F +
Sbjct: 314 SGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGMFNFDTFW 373
Query: 371 TSLSASSSIIATDNV 385
+ + I D +
Sbjct: 374 KNFKSKLGFINWDAI 388
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 43.1 bits (100), Expect = 5e-04
Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 4/148 (2%)
Query: 232 GFPVNNSSSDNAQNFS-FKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGF 290
G P +N + + + F + G G+P G G+ G +++ + +
Sbjct: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
Query: 291 GKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGS 350
G+ +F + A + PG+ + AS P GGGSS +G GS GS
Sbjct: 194 GQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS-GS 250
Query: 351 HSHTAFSKPSSDTFGNSSISTSLSASSS 378
S ++ S + D SS S S SSS
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
Score = 32.7 bits (73), Expect = 0.64
Identities = 43/178 (24%), Positives = 66/178 (37%), Gaps = 22/178 (12%)
Query: 210 GVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDN--------AQNFSFKTNSGFAAASSGS 261
G N P FG + A PG+ +S+ N + + +NSG + S
Sbjct: 196 GGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
Query: 262 PAGFGSS-----------PAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASS 310
+G GS+ + G+++ SSG S+ + G S + S+ S SS
Sbjct: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
Query: 311 FGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPG-SHSHTAFSKPSSDTFGNS 367
G+ G SG G + G S + GF G S + SK + G S
Sbjct: 314 SGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGS 371
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 43.1 bits (100), Expect = 5e-04
Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 4/148 (2%)
Query: 232 GFPVNNSSSDNAQNFS-FKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGF 290
G P +N + + + F + G G+P G G+ G +++ + +
Sbjct: 134 GVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPW 193
Query: 291 GKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGS 350
G+ +F + A + PG+ + AS P GGGSS +G GS GS
Sbjct: 194 GQGGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGS-GS 250
Query: 351 HSHTAFSKPSSDTFGNSSISTSLSASSS 378
S ++ S + D SS S S SSS
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
Score = 30.0 bits (66), Expect = 4.1
Identities = 32/128 (25%), Positives = 51/128 (39%), Gaps = 21/128 (16%)
Query: 210 GVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDN--------AQNFSFKTNSGFAAASSGS 261
G N P FG + A PG+ +S+ N + + +NSG + S
Sbjct: 196 GGNGGPPNFGTNTQGAVA--QPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSG 253
Query: 262 PAGFGSS-----------PAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASS 310
+G GS+ + G+++ SSG S+ + G S + S+ S SS
Sbjct: 254 SSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
Query: 311 FGSPGFSG 318
G+ G SG
Sbjct: 314 SGNHGGSG 321
>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
Length = 508
Score = 42.0 bits (97), Expect = 0.001
Identities = 40/164 (24%), Positives = 72/164 (43%), Gaps = 2/164 (1%)
Query: 198 STKVALLSDVKDGVNQAAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAA 257
ST +A+L+ + + +P+ S +++F P SSS ++ + + +S +
Sbjct: 14 STPLAMLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFG 73
Query: 258 SSGSPAGFGSSPAFGAAASTSSGISTS-APAFGFGKPEVTSAASFSFKSPAASSFGSPGF 316
SG+ GSS A AAA+ ++ + + +F G +SA S + S AA++ +
Sbjct: 74 VSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAA 133
Query: 317 -SGLPASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKP 359
S P + +AP GG G G +HS +P
Sbjct: 134 ASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQP 177
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 42.0 bits (97), Expect = 0.001
Identities = 45/133 (33%), Positives = 61/133 (45%), Gaps = 20/133 (15%)
Query: 252 SGFAAASSGSPAGFGSSPAFGAAASTSSGIST--SAPAFGFGKPEVTSAASFSFKSPAAS 309
SG A SGS G+SP AA+S +S S+ S+P+ P V +A+ A
Sbjct: 2 SGSRQAGSGSA---GTSPGSSAASSVTSASSSLSSSPS----PPSVAVSAAALVSGGVAQ 54
Query: 310 SFGSPGFSGLPASLATGPVRAP-VAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSS 368
+ GS G G PVR VAPA G S G S G H+ ++PS+ G+SS
Sbjct: 55 AAGSGGLGG--------PVRPVLVAPAVSG--SGGGAVSTGLSRHSCAARPSAGVGGSSS 104
Query: 369 ISTSLSASSSIIA 381
S S ++A
Sbjct: 105 SLGSGSRKRPLLA 117
Score = 33.5 bits (75), Expect = 0.37
Identities = 40/121 (33%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 238 SSSDNAQNFSFKTNSGFAAASSGSPAG--FGSSP-----AFGAAASTSSGISTSAPAFGF 290
S S A + S T+ G +AASS + A SSP A AAA S G++ +A + G
Sbjct: 2 SGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGL 61
Query: 291 GKP--EVTSAASFSFKSPAASSFG----------SPGFSGLPASLATGPVRAP-VAPAFG 337
G P V A + S A S G S G G +SL +G + P +AP
Sbjct: 62 GGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCN 121
Query: 338 G 338
G
Sbjct: 122 G 122
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 42.0 bits (97), Expect = 0.001
Identities = 45/133 (33%), Positives = 61/133 (45%), Gaps = 20/133 (15%)
Query: 252 SGFAAASSGSPAGFGSSPAFGAAASTSSGIST--SAPAFGFGKPEVTSAASFSFKSPAAS 309
SG A SGS G+SP AA+S +S S+ S+P+ P V +A+ A
Sbjct: 2 SGSRQAGSGSA---GTSPGSSAASSVTSASSSLSSSPS----PPSVAVSAAALVSGGVAQ 54
Query: 310 SFGSPGFSGLPASLATGPVRAP-VAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSS 368
+ GS G G PVR VAPA G S G S G H+ ++PS+ G+SS
Sbjct: 55 AAGSGGLGG--------PVRPVLVAPAVSG--SGGGAVSTGLSRHSCAARPSAGVGGSSS 104
Query: 369 ISTSLSASSSIIA 381
S S ++A
Sbjct: 105 SLGSGSRKRPLLA 117
Score = 33.5 bits (75), Expect = 0.37
Identities = 40/121 (33%), Positives = 53/121 (43%), Gaps = 20/121 (16%)
Query: 238 SSSDNAQNFSFKTNSGFAAASSGSPAG--FGSSP-----AFGAAASTSSGISTSAPAFGF 290
S S A + S T+ G +AASS + A SSP A AAA S G++ +A + G
Sbjct: 2 SGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGL 61
Query: 291 GKP--EVTSAASFSFKSPAASSFG----------SPGFSGLPASLATGPVRAP-VAPAFG 337
G P V A + S A S G S G G +SL +G + P +AP
Sbjct: 62 GGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCN 121
Query: 338 G 338
G
Sbjct: 122 G 122
>gi|26051237 nucleoporin 54kDa [Homo sapiens]
Length = 507
Score = 42.0 bits (97), Expect = 0.001
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 12/80 (15%)
Query: 214 AAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSP-AGFGSSPAFG 272
AAPA GFG GF ++++ +A +FS TN+G G+ GFG FG
Sbjct: 19 AAPAGGFG----------GFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
Query: 273 AAASTSSGISTS-APAFGFG 291
TS+G+ T GFG
Sbjct: 69 TTTGTSTGLGTGLGTGLGFG 88
Score = 35.0 bits (79), Expect = 0.13
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 15/128 (11%)
Query: 271 FGAAASTS-SGISTSAPAFGFG---KPEVTSAASFSFKSPAASS----FG---SPGFSGL 319
FGA + TS + +T+APA GFG T+ ++FSF +P + FG + GF
Sbjct: 5 FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
Query: 320 PASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHT---AFSKPS-SDTFGNSSISTSLSA 375
T + G G GF + T FS+P+ + T N I+T+ +
Sbjct: 65 TGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINTASAL 124
Query: 376 SSSIIATD 383
S+ + D
Sbjct: 125 SAPTLLGD 132
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 8/164 (4%)
Query: 230 SPGF-PVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAF 288
SP + P + S S + N+S + S + S SP SP + + TS S ++P++
Sbjct: 1619 SPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1678
Query: 289 GFGKPEVT-SAASFSFKSPAASSFGSPGFSGL-PASLATGPVRAPVAPAFGGGSSVAGFG 346
P + ++ S+S SP+ S SP +S P+ T P +P +P++ S +
Sbjct: 1679 SPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPSYSPTSPSY---SPTSPSY 1734
Query: 347 SPGSHSHTAFSKPSSDTFGN-SSISTSLSASSSIIATDNVLFTP 389
SP S S++ S S T N + S S S +S + + +TP
Sbjct: 1735 SPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTP 1778
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/173 (27%), Positives = 79/173 (45%), Gaps = 21/173 (12%)
Query: 214 AAPAFGFGSSQAATFMSPGFP-VNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSS---- 268
A PA+G S + M+PG + S++ +A FS G++ A S +P GS
Sbjct: 1524 ATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFS----PGYSPAWSPTPGSPGSPGPSS 1579
Query: 269 ---PAFGAAASTSSGISTSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGL-PASLA 324
P+ G A S S S ++PA+ E S ++ +SP+ S SP +S P+
Sbjct: 1580 PYIPSPGGAMSPS--YSPTSPAY-----EPRSPGGYTPQSPSYSPT-SPSYSPTSPSYSP 1631
Query: 325 TGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSSISTSLSASS 377
T P +P +P++ S SP + P+S ++ +S S S ++ S
Sbjct: 1632 TSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1684
Score = 39.7 bits (91), Expect = 0.005
Identities = 43/157 (27%), Positives = 73/157 (46%), Gaps = 7/157 (4%)
Query: 215 APAFGFGSSQAATFMSPGF-PVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGA 273
+PA+ S T SP + P + S S + ++S + + + S SP SP +
Sbjct: 1597 SPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPS 1656
Query: 274 AASTSSGISTSAPAFGFGKPEVT-SAASFSFKSPAASSFGSPGFSGL-PASLATGPVRAP 331
+ TS S ++P++ P + ++ S+S SP+ S SP +S P+ T P +P
Sbjct: 1657 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPSYSP 1715
Query: 332 VAPAFGGGSSVAGFGSPGSHSHTAFSKPSSDTFGNSS 368
+P++ S + SP S S++ S S T N S
Sbjct: 1716 TSPSY---SPTSPSYSPTSPSYSPTSPSYSPTSPNYS 1749
Score = 38.9 bits (89), Expect = 0.009
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 4/146 (2%)
Query: 230 SPGF-PVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAF 288
SP + P + S S + ++S + S + S SP SP + + TS S ++P +
Sbjct: 1689 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNY 1748
Query: 289 GFGKPEVT-SAASFSFKSPAASSFGSPGFSGL-PASLATGPVRAPVAPAFGGGSSVAGFG 346
P T ++ S+S SP+ S SP ++ P T P +P +P++ S
Sbjct: 1749 SPTSPNYTPTSPSYSPTSPSYSPT-SPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPS 1807
Query: 347 SPGSHSHTAFSKPSSDTFGNSSISTS 372
SP + PSS ++ SS S S
Sbjct: 1808 SPRYTPQSPTYTPSSPSYSPSSPSYS 1833
Score = 36.6 bits (83), Expect = 0.044
Identities = 39/148 (26%), Positives = 62/148 (41%), Gaps = 9/148 (6%)
Query: 230 SPGF-PVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAF 288
SP + P + S S + ++S + + + + SP SP + + TS S S+P +
Sbjct: 1752 SPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRY 1811
Query: 289 GFGKPEVT-SAASFSFKSPAASSFG------SPGFS-GLPASLATGPVRAPVAPAFGGGS 340
P T S+ S+S SP+ S SP +S P T P +P +P + S
Sbjct: 1812 TPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTS 1871
Query: 341 SVAGFGSPGSHSHTAFSKPSSDTFGNSS 368
SP T P+S T+ +S
Sbjct: 1872 PKYSPTSPTYSPTTPKYSPTSPTYSPTS 1899
Score = 36.2 bits (82), Expect = 0.058
Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 30/165 (18%)
Query: 255 AAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFGFGKPEVTS-----AASFSFKSPAAS 309
AA +G G SP G + + + + PA+G P V S AA FS + + +
Sbjct: 1495 AAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDA 1554
Query: 310 SFGSPGFS-------GLPASL------------ATGPVRAPVAPAF-----GGGSSVAGF 345
S SPG+S G P S A P +P +PA+ GG + +
Sbjct: 1555 SGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPS 1614
Query: 346 GSPGSHSHTAFSKPSSDTFGN-SSISTSLSASSSIIATDNVLFTP 389
SP S S++ S S T N S S S S +S + + ++P
Sbjct: 1615 YSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSP 1659
Score = 33.9 bits (76), Expect = 0.29
Identities = 36/142 (25%), Positives = 61/142 (42%), Gaps = 4/142 (2%)
Query: 230 SPGF-PVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAF 288
SP + P + S S + ++S + S + S SP SP TS S ++P++
Sbjct: 1710 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSY 1769
Query: 289 GFGKPEVT-SAASFSFKSPAASSFGSPGFSGL-PASLATGPVRAPVAPAFGGGSSVAGFG 346
P T ++ ++S SP+ S SP +S P+ + P P +P + S
Sbjct: 1770 SPTSPNYTPTSPNYSPTSPSYSP-TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPS 1828
Query: 347 SPGSHSHTAFSKPSSDTFGNSS 368
SP + P+S ++ SS
Sbjct: 1829 SPSYSPTSPKYTPTSPSYSPSS 1850
>gi|67782356 corneodesmosin precursor [Homo sapiens]
Length = 529
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 3/124 (2%)
Query: 264 GFGSSPAFGA-AASTSSGIS-TSAPAFGFGKPEVTSAASFSFKSPAASSFGSPGFSGLPA 321
G G S F + + S+SSG S +SA + G G +S +S + A S G+S +
Sbjct: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
Query: 322 SLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHTAFS-KPSSDTFGNSSISTSLSASSSII 380
S +G + + GSS + GS GSHS ++ S SS +F SS S + S++
Sbjct: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALP 177
Query: 381 ATDN 384
DN
Sbjct: 178 TNDN 181
Score = 37.7 bits (86), Expect = 0.020
Identities = 45/165 (27%), Positives = 66/165 (40%), Gaps = 16/165 (9%)
Query: 230 SPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSPAGFGSSPAFGAAASTSSGISTSAPAFG 289
S GF + SS + + S +SG SSGS +G S G+A S G S ++
Sbjct: 62 SSGFSSYSGSSSSGSSISSARSSG--GGSSGSSSG-SSIAQGGSAGSFKPGTGYSQVSYS 118
Query: 290 FGKPEVTSAASFSFKSPAASSFGSPGFSGLPASLATGPVRAPVAPAFGGGSSVAGFGSPG 349
G AS S S SS G SG + ++ + + F S G GS
Sbjct: 119 SGSGSSLQGASGS--SQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSAL 176
Query: 350 SHSHTAF-----------SKPSSDTFGNSSISTSLSASSSIIATD 383
+ ++ S SS TFG SS S+S++ ++D
Sbjct: 177 PTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD 221
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,976,134
Number of Sequences: 37866
Number of extensions: 924421
Number of successful extensions: 5060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 281
Number of HSP's that attempted gapping in prelim test: 3901
Number of HSP's gapped (non-prelim): 1034
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.