BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62945417 dystrophia myotonica-containing WD repeat motif protein [Homo sapiens] (674 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62945417 dystrophia myotonica-containing WD repeat motif prot... 1394 0.0 gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens] 636 0.0 gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens] 636 0.0 gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens] 517 e-146 gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens] 501 e-142 gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 2e-07 gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 55 2e-07 gi|13376840 WD repeat domain 61 [Homo sapiens] 54 6e-07 gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 52 1e-06 gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 52 2e-06 gi|113865883 WD repeat domain 38 [Homo sapiens] 52 2e-06 gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 51 3e-06 gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 51 3e-06 gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 51 4e-06 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 50 5e-06 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 50 7e-06 gi|39812378 RAN binding protein 9 [Homo sapiens] 50 7e-06 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 50 7e-06 gi|134142824 forkhead box D2 [Homo sapiens] 50 9e-06 gi|7706501 WW domain binding protein 11 [Homo sapiens] 50 9e-06 gi|26665869 WD repeat domain 51B [Homo sapiens] 50 9e-06 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 49 1e-05 gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 49 2e-05 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 49 2e-05 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 49 2e-05 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 49 2e-05 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 49 2e-05 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 49 2e-05 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 49 2e-05 gi|56549694 enabled homolog isoform a [Homo sapiens] 49 2e-05 >gi|62945417 dystrophia myotonica-containing WD repeat motif protein [Homo sapiens] Length = 674 Score = 1394 bits (3608), Expect = 0.0 Identities = 674/674 (100%), Positives = 674/674 (100%) Query: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ Sbjct: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60 Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG Sbjct: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 Query: 121 SGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETI 180 SGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETI Sbjct: 121 SGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETI 180 Query: 181 SLLVGFSAGQVQYLDLIKKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYL 240 SLLVGFSAGQVQYLDLIKKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYL Sbjct: 181 SLLVGFSAGQVQYLDLIKKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYL 240 Query: 241 YNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLA 300 YNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLA Sbjct: 241 YNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLA 300 Query: 301 CVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRV 360 CVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRV Sbjct: 301 CVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRV 360 Query: 361 VARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSP 420 VARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSP Sbjct: 361 VARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSP 420 Query: 421 LPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGE 480 LPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGE Sbjct: 421 LPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGE 480 Query: 481 PGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEH 540 PGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEH Sbjct: 481 PGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEH 540 Query: 541 KRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKK 600 KRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKK Sbjct: 541 KRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKK 600 Query: 601 IAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQTGEGSWPRSPSKSVVEG 660 IAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQTGEGSWPRSPSKSVVEG Sbjct: 601 IAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQTGEGSWPRSPSKSVVEG 660 Query: 661 ISSQPGNSPSGTVV 674 ISSQPGNSPSGTVV Sbjct: 661 ISSQPGNSPSGTVV 674 >gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens] Length = 581 Score = 636 bits (1641), Expect = 0.0 Identities = 341/621 (54%), Positives = 405/621 (65%), Gaps = 77/621 (12%) Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80 EIK+QF TREG YKLLP +R P P + S P Sbjct: 12 EIKTQFTTREGLYKLLPHSEYSR---------------PNRVPFNSQGSNP--------- 47 Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGC 140 VR+S V L D +G GDR+CFN+GRELYFY Sbjct: 48 -------------VRVSFVNLN--DQSG-------------NGDRLCFNVGRELYFY--- 76 Query: 141 CRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLIKKD 200 +G +++ DL+KPIDKRIYKGTQPTCHDFN TA E++SLLVGFSAGQVQ +D IKK+ Sbjct: 77 IYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKE 136 Query: 201 TSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQG 260 TSKLFNEERLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQG Sbjct: 137 TSKLFNEERLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQG 196 Query: 261 EGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRG 320 E F+V+ KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G Sbjct: 197 ESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHG 256 Query: 321 LMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYT 380 MKSYFGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYT Sbjct: 257 TMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYT 316 Query: 381 TRAEEAATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGS 433 T EE G E SG +E+ + A T S S + S+TYRFGS Sbjct: 317 TSVEE-----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGS 371 Query: 434 AGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSR 492 GQDTQ CLWDLTED+L+PH PL+R RT T P A S+ PG +P L R Sbjct: 372 VGQDTQLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPR 431 Query: 493 SNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRG 552 SNSLPH A AG + + +FATL+L +R++R EK+HKR HS+G+IS Sbjct: 432 SNSLPHSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS-- 488 Query: 553 GSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFL 612 S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FL Sbjct: 489 ------SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFL 542 Query: 613 EDCIITACQEGLICTWARPGK 633 EDCI+TACQEG ICTW RPGK Sbjct: 543 EDCIVTACQEGFICTWGRPGK 563 >gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens] Length = 569 Score = 636 bits (1641), Expect = 0.0 Identities = 341/621 (54%), Positives = 405/621 (65%), Gaps = 77/621 (12%) Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80 EIK+QF TREG YKLLP +R P P + S P Sbjct: 12 EIKTQFTTREGLYKLLPHSEYSR---------------PNRVPFNSQGSNP--------- 47 Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGC 140 VR+S V L D +G GDR+CFN+GRELYFY Sbjct: 48 -------------VRVSFVNLN--DQSG-------------NGDRLCFNVGRELYFY--- 76 Query: 141 CRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLIKKD 200 +G +++ DL+KPIDKRIYKGTQPTCHDFN TA E++SLLVGFSAGQVQ +D IKK+ Sbjct: 77 IYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKE 136 Query: 201 TSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQG 260 TSKLFNEERLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQG Sbjct: 137 TSKLFNEERLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQG 196 Query: 261 EGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRG 320 E F+V+ KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G Sbjct: 197 ESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHG 256 Query: 321 LMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYT 380 MKSYFGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYT Sbjct: 257 TMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYT 316 Query: 381 TRAEEAATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGS 433 T EE G E SG +E+ + A T S S + S+TYRFGS Sbjct: 317 TSVEE-----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGS 371 Query: 434 AGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSR 492 GQDTQ CLWDLTED+L+PH PL+R RT T P A S+ PG +P L R Sbjct: 372 VGQDTQLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPR 431 Query: 493 SNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRG 552 SNSLPH A AG + + +FATL+L +R++R EK+HKR HS+G+IS Sbjct: 432 SNSLPHSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS-- 488 Query: 553 GSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFL 612 S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FL Sbjct: 489 ------SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFL 542 Query: 613 EDCIITACQEGLICTWARPGK 633 EDCI+TACQEG ICTW RPGK Sbjct: 543 EDCIVTACQEGFICTWGRPGK 563 >gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens] Length = 508 Score = 517 bits (1331), Expect = e-146 Identities = 296/621 (47%), Positives = 353/621 (56%), Gaps = 138/621 (22%) Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80 EIK+QF TREG YKLLP +R P P + S P Sbjct: 12 EIKTQFTTREGLYKLLPHSEYSR---------------PNRVPFNSQGSNP--------- 47 Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGC 140 VR+S V L D +G GDR+CFN+GRELYFY Sbjct: 48 -------------VRVSFVNLN--DQSG-------------NGDRLCFNVGRELYFY--- 76 Query: 141 CRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLIKKD 200 IYKG + Sbjct: 77 ------------------IYKGVR------------------------------------ 82 Query: 201 TSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQG 260 +RLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQG Sbjct: 83 -------KRLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQG 135 Query: 261 EGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRG 320 E F+V+ KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G Sbjct: 136 ESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHG 195 Query: 321 LMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYT 380 MKSYFGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYT Sbjct: 196 TMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYT 255 Query: 381 TRAEEAATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGS 433 T EE G E SG +E+ + A T S S + S+TYRFGS Sbjct: 256 TSVEE-----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGS 310 Query: 434 AGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSR 492 GQDTQ CLWDLTED+L+PH PL+R RT T P A S+ PG +P L R Sbjct: 311 VGQDTQLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPR 370 Query: 493 SNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRG 552 SNSLPH A AG + + +FATL+L +R++R EK+HKR HS+G+IS Sbjct: 371 SNSLPHSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS-- 427 Query: 553 GSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFL 612 S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FL Sbjct: 428 ------SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFL 481 Query: 613 EDCIITACQEGLICTWARPGK 633 EDCI+TACQEG ICTW RPGK Sbjct: 482 EDCIVTACQEGFICTWGRPGK 502 >gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens] Length = 445 Score = 501 bits (1290), Expect = e-142 Identities = 254/436 (58%), Positives = 303/436 (69%), Gaps = 22/436 (5%) Query: 206 NEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQGEGFSV 265 + ERLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQGE F+V Sbjct: 18 SHERLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGESFAV 77 Query: 266 YAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSY 325 + KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G MKSY Sbjct: 78 HTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHGTMKSY 137 Query: 326 FGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEE 385 FGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYTT EE Sbjct: 138 FGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYTTSVEE 197 Query: 386 AATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDT 438 G E SG +E+ + A T S S + S+TYRFGS GQDT Sbjct: 198 -----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGSVGQDT 252 Query: 439 QFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSRSNSLP 497 Q CLWDLTED+L+PH PL+R RT T P A S+ PG +P L RSNSLP Sbjct: 253 QLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPRSNSLP 312 Query: 498 HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGS 557 H A AG + + +FATL+L +R++R EK+HKR HS+G+IS Sbjct: 313 HSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS------- 364 Query: 558 GSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFLEDCII 617 S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FLEDCI+ Sbjct: 365 -SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFLEDCIV 423 Query: 618 TACQEGLICTWARPGK 633 TACQEG ICTW RPGK Sbjct: 424 TACQEGFICTWGRPGK 439 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 55.5 bits (132), Expect = 2e-07 Identities = 45/129 (34%), Positives = 53/129 (41%), Gaps = 18/129 (13%) Query: 3 AGGAEGGSGPGA----AMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQP 58 AG A G+GP A A G E R R PG G +R GP S + P+ P Sbjct: 68 AGAA--GAGPAAPAEGAPGAAPEPPPAGRAR-------PGGGGPQRPGPPSPRRPLVPAG 118 Query: 59 PQPP-----PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113 P PP P P ++G A PA++ AGP P PA PA L G G P Sbjct: 119 PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178 Query: 114 ATPAGLGSG 122 G G G Sbjct: 179 GPGPGPGPG 187 Score = 48.9 bits (115), Expect = 2e-05 Identities = 27/62 (43%), Positives = 30/62 (48%), Gaps = 5/62 (8%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA----AGPASSPPPA-GPGPGPAL 91 P +G+A P A V P P GPA +GP A AGP P P GPGPGP Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188 Query: 92 PA 93 PA Sbjct: 189 PA 190 Score = 43.1 bits (100), Expect = 8e-04 Identities = 38/115 (33%), Positives = 44/115 (38%), Gaps = 15/115 (13%) Query: 10 SGPGAAM---GDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPP----QPP 62 +GPGAA G A + S + G A +A V PP P Sbjct: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249 Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPA 117 P PA+ S P A PA+ P A P P P PA L P AG P A PA Sbjct: 250 PAPAAPSPPAAPAPAA--PAAAPPPPPPAPAT------LARPPGHPAGPPTAAPA 296 Score = 40.8 bits (94), Expect = 0.004 Identities = 42/154 (27%), Positives = 53/154 (34%), Gaps = 24/154 (15%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQP-----PPGPASASGPGAAGPASSPPPAGPGPGPAL 91 P GAA PA+ P P P P PP PA A+ G + PP A P P Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301 Query: 92 PAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGCCRRGSQRSIDL 151 A SAGA PA AG +G V G PG + Sbjct: 302 AA--------QNGGSAGAAPAPAPAAGGPAG---VSGQPG------PGAAAAAPAPGVKA 344 Query: 152 NKPIDKRIYKGTQPTCHDFNQFTAATETISLLVG 185 P KR+ + P A+ S+++G Sbjct: 345 ESP--KRVVQAAPPAAQTLAASGPASTAASMVIG 376 Score = 40.0 bits (92), Expect = 0.007 Identities = 42/127 (33%), Positives = 48/127 (37%), Gaps = 29/127 (22%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAAR------RSGPASAQTPVP-PQ 57 G G GPG G A +T G LL AA +GPA A P+P P Sbjct: 179 GPGPGPGPGKPAGPGAA-----QTLNGSAALLNSHHAAAPAVSLVNNGPA-ALLPLPKPA 232 Query: 58 PP----QPPP--GPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111 P Q PP G A+ P A P ++P PA P P P P A Sbjct: 233 APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP----------PAPATLAR 282 Query: 112 PPATPAG 118 PP PAG Sbjct: 283 PPGHPAG 289 Score = 37.4 bits (85), Expect = 0.046 Identities = 46/150 (30%), Positives = 52/150 (34%), Gaps = 28/150 (18%) Query: 383 AEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCL 442 A AA A GA G E P A GG P P P S AG Sbjct: 73 AGPAAPAEGAPGAAP-----EPPPAGRARPGGGGPQRPGPP--SPRRPLVPAG------- 118 Query: 443 WDLTEDVLYPHPPLARTRTLP----GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPH 498 P PP A+ R P G+ P AA+ + G EP P P + +L Sbjct: 119 ---------PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG-PAKPAGPAALAA 168 Query: 499 PAGGGKAGGPGVAAEPGTPFSIGRFATLTL 528 AG G GPG PG G A TL Sbjct: 169 RAGPGPGPGPGPGPGPGPGKPAGPGAAQTL 198 Score = 34.3 bits (77), Expect = 0.39 Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 15/69 (21%) Query: 65 PASASGPGAAGPAS-------SPPPAG---PGPG----PALPAVRLSLVRLG-EPDSAGA 109 PA A+G G A PA PPPAG PG G P P+ R LV G P +A Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126 Query: 110 GEPPATPAG 118 PP AG Sbjct: 127 RPPPEGSAG 135 Score = 33.5 bits (75), Expect = 0.66 Identities = 37/124 (29%), Positives = 43/124 (34%), Gaps = 24/124 (19%) Query: 414 GGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAA 473 G A L PLPK + G+ Q F P PP A P PP A Sbjct: 221 GPAALLPLPKPAAP----GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA 276 Query: 474 SSSRGGEPG--PGP------LPRSLSRSNS-------LPHPAGGGKAG-----GPGVAAE 513 ++ PG GP +P + N P PA GG AG GPG AA Sbjct: 277 PATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAA 336 Query: 514 PGTP 517 P Sbjct: 337 APAP 340 Score = 33.5 bits (75), Expect = 0.66 Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 12/74 (16%) Query: 452 PHPPLARTRTLP---------GTPGTTPPAASS---SRGGEPGPGPLPRSLSRSNSLPHP 499 P PP T P P PPAA+ S G P P P + + P P Sbjct: 272 PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331 Query: 500 AGGGKAGGPGVAAE 513 A PGV AE Sbjct: 332 GAAAAAPAPGVKAE 345 Score = 31.2 bits (69), Expect = 3.3 Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 35/128 (27%) Query: 4 GGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPP 63 G A P A G A + Q PG GAA + + P + Q P Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQ-----------PGPGAAAAAPAPGVKAESPKRVVQAAP 355 Query: 64 ---------GPASAS-----GPGAAG----PASSPPPAGPGPGPALP-----AVRLSLVR 100 GPAS + GP G PA+ PPPA PG LP AV SL R Sbjct: 356 PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPA-PGTPTGLPKGAAGAVTQSLSR 414 Query: 101 LGEPDSAG 108 ++G Sbjct: 415 TPTATTSG 422 >gi|62234461 Notchless gene homolog isoform a [Homo sapiens] Length = 485 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Query: 291 AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLV 350 AFSP G++LA S D +R + + K + +L + WSPDGR + +G ++ + Sbjct: 121 AFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQI 180 Query: 351 TVWSFTEGRVVARG-HGHKSWVNAVAFDPYTTRAE 384 +W + G+ V R GH W+ ++++P E Sbjct: 181 LLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPE 215 Score = 52.0 bits (123), Expect = 2e-06 Identities = 28/123 (22%), Positives = 55/123 (44%) Query: 256 LLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDS 315 L+ + F+++ + PL + + +N+ FSPD R +A S D ++++ + Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403 Query: 316 MLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVA 375 ++ + + + WS D R +V+G D + VW ++ GH V AV Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 463 Query: 376 FDP 378 + P Sbjct: 464 WSP 466 Score = 45.8 bits (107), Expect = 1e-04 Identities = 42/176 (23%), Positives = 70/176 (39%), Gaps = 18/176 (10%) Query: 278 AKWAVGEG--PLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWS 335 +KW G PL+ +P+ R++A S+DG +R++ + ++ + + C+ W Sbjct: 199 SKWITGLSWEPLHA---NPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWG 255 Query: 336 PDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFD---PYTTRAEEAATAAGA 392 DG + + +D + VW +G + GH WVN +A T A E A A+ Sbjct: 256 GDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVN 314 Query: 393 DGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448 + G +E + A + G R S D LW ED Sbjct: 315 PQDLQGSLQELKERALSRYNL---------VRGQGPERLVSGSDDFTLFLWSPAED 361 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/65 (32%), Positives = 34/65 (52%) Query: 289 EFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDD 348 + A+S D R L S D L+V+ + L + + + V WSPDG+ V +GG+D Sbjct: 419 QIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 478 Query: 349 LVTVW 353 + +W Sbjct: 479 CLRIW 483 Score = 35.8 bits (81), Expect = 0.13 Identities = 14/57 (24%), Positives = 29/57 (50%) Query: 322 MKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378 ++ + ++ V +SP G+Y+ +G D V W + GH+ WV ++++ P Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSP 166 Score = 31.2 bits (69), Expect = 3.3 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 10/92 (10%) Query: 291 AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGG---LLCVCW-----SPDGRYVV 342 ++SPDGR LA ++G ++ +D + + ++ G + + W +P+ RYV Sbjct: 163 SWSPDGRKLASGCKNG--QILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVA 220 Query: 343 TGGEDDLVTVWSFTEGRVVARGHGHKSWVNAV 374 + +D V +W T GR GH V + Sbjct: 221 SSSKDGSVRIWDTTAGRCERILTGHTQSVTCL 252 >gi|13376840 WD repeat domain 61 [Homo sapiens] Length = 305 Score = 53.5 bits (127), Expect = 6e-07 Identities = 27/91 (29%), Positives = 47/91 (51%) Query: 291 AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLV 350 A+SPDG++LA + DG + +F + L ++ + + + +SPD + +VT +D + Sbjct: 155 AYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYI 214 Query: 351 TVWSFTEGRVVARGHGHKSWVNAVAFDPYTT 381 ++ + GH SWV VAF P T Sbjct: 215 KIYDVQHANLAGTLSGHASWVLNVAFCPDDT 245 Score = 51.2 bits (121), Expect = 3e-06 Identities = 25/100 (25%), Positives = 54/100 (54%), Gaps = 2/100 (2%) Query: 281 AVGEGPLNEF--AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDG 338 ++ GP++ + AFSPD ++LA + G + +F +S + + +L + +SPDG Sbjct: 101 SIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDG 160 Query: 339 RYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378 +Y+ +G D ++ ++ G+++ GH + ++ F P Sbjct: 161 KYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSP 200 Score = 44.7 bits (104), Expect = 3e-04 Identities = 24/92 (26%), Positives = 39/92 (42%) Query: 286 PLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGG 345 P+ FSPD + L S DG ++++ L G + + +L V + PD + V+ Sbjct: 192 PIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSS 251 Query: 346 EDDLVTVWSFTEGRVVARGHGHKSWVNAVAFD 377 D V VW V H+ V V ++ Sbjct: 252 SDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYN 283 >gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] Length = 357 Score = 52.4 bits (124), Expect = 1e-06 Identities = 78/347 (22%), Positives = 116/347 (33%), Gaps = 74/347 (21%) Query: 88 GPALPAVRLSLVR----LGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPG---- 139 GP LP V + R LG GAG+ ATP L G C +L + G Sbjct: 9 GPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIMLLSGHEGE 68 Query: 140 --CCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLI 197 CC+ S + D+ I +N + + + L G S G V L Sbjct: 69 VYCCKFHPNGSTLASAGFDRLILL--------WNVY-GDCDNYATLKGHS-GAVMELHY- 117 Query: 198 KKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLL 257 D S LF+ DKT + +SE+ GH N +P P Sbjct: 118 NTDGSMLFSAST--DKTVAVW-----DSETGERVKRLKGHTSFVNSCYPARRGPQLVCTG 170 Query: 258 KQGEGFSVYAAKSKAP---------------------------RNPLAKWAVGEGPLNE- 289 ++ + KA N + W + + L Sbjct: 171 SDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT 230 Query: 290 ----------FAFSPDGRHLACVSQDGCLRVFHFDSM--------LLRGLMKSYFGGLLC 331 + S +G +L + D +RV+ + +G + ++ LL Sbjct: 231 MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLR 290 Query: 332 VCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378 WSPDG + G D V VW T R++ + GH +N VAF P Sbjct: 291 CSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHP 337 Score = 37.4 bits (85), Expect = 0.046 Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 5/111 (4%) Query: 284 EGPLNEFAFSPDGRHLACVSQDGCLRVFH-FDSMLLRGLMKSYFGGLLCVCWSPDGRYVV 342 EG + F P+G LA D + +++ + +K + G ++ + ++ DG + Sbjct: 66 EGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLF 125 Query: 343 TGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGAD 393 + D V VW G V R GH S+VN+ Y R G+D Sbjct: 126 SASTDKTVAVWDSETGERVKRLKGHTSFVNSC----YPARRGPQLVCTGSD 172 >gi|62234438 Notchless gene homolog isoform b [Homo sapiens] Length = 193 Score = 52.0 bits (123), Expect = 2e-06 Identities = 28/123 (22%), Positives = 55/123 (44%) Query: 256 LLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDS 315 L+ + F+++ + PL + + +N+ FSPD R +A S D ++++ + Sbjct: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111 Query: 316 MLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVA 375 ++ + + + WS D R +V+G D + VW ++ GH V AV Sbjct: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171 Query: 376 FDP 378 + P Sbjct: 172 WSP 174 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/65 (32%), Positives = 34/65 (52%) Query: 289 EFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDD 348 + A+S D R L S D L+V+ + L + + + V WSPDG+ V +GG+D Sbjct: 127 QIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 186 Query: 349 LVTVW 353 + +W Sbjct: 187 CLRIW 191 >gi|113865883 WD repeat domain 38 [Homo sapiens] Length = 314 Score = 51.6 bits (122), Expect = 2e-06 Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 5/133 (3%) Query: 248 ASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVG--EGPLNEFAFSPDGRHLACVSQD 305 A +P LL E VY ++++ + W +G GP+ FSPDG A S D Sbjct: 28 AFSPDGQMLLTGSEDGCVYGWETRSGQ---LLWRLGGHTGPVKFCRFSPDGHLFASASCD 84 Query: 306 GCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGH 365 +R++ ++K + + V +SPD R + +GG D V +W G+++ Sbjct: 85 CTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLV 144 Query: 366 GHKSWVNAVAFDP 378 GH+ + + F P Sbjct: 145 GHRDSIQSSDFSP 157 Score = 49.3 bits (116), Expect = 1e-05 Identities = 29/94 (30%), Positives = 44/94 (46%) Query: 285 GPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTG 344 G +N AFSPDG+ L S+DGC+ + S L + + G + +SPDG + Sbjct: 22 GEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASA 81 Query: 345 GEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378 D V +W + + GH+ V V+F P Sbjct: 82 SCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSP 115 Score = 40.8 bits (94), Expect = 0.004 Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 4/90 (4%) Query: 292 FSPDGRHLACVSQDGCLRVFHFDSM---LLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDD 348 FSP LA S D + ++ + + ++ + + C+C+S G + +G D Sbjct: 155 FSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LLASGSWDK 213 Query: 349 LVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378 + +W T ++ + GH +WV ++AF P Sbjct: 214 TIHIWKPTTSSLLIQLKGHVTWVKSIAFSP 243 >gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] Length = 1120 Score = 51.2 bits (121), Expect = 3e-06 Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 20/131 (15%) Query: 10 SGPGAAMGDC-AEIKSQFRTREGFYKLL---PGDGAARRSGPASAQTPVPPQPPQ----- 60 S PG GD E + + G Y L PG A R+ P+ TP P Sbjct: 720 SRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFAL 779 Query: 61 -------PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPP P S +GP+ PPP PGP A L EP AG EPP Sbjct: 780 RARRKGPPPPPPKRLSS--VSGPSPEPPPLDESPGPKEGATGPRRRTLSEP--AGPSEPP 835 Query: 114 ATPAGLGSGGD 124 PA G D Sbjct: 836 GPPAPAGPASD 846 Score = 38.9 bits (89), Expect = 0.016 Identities = 36/100 (36%), Positives = 40/100 (40%), Gaps = 23/100 (23%) Query: 42 ARRSGP--------ASAQTPVPPQPP-QPPPGPASASGPGAAGP--ASSPPPAGPG--PG 88 ARR GP +S P P PP PGP GA GP + PAGP PG Sbjct: 781 ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKE----GATGPRRRTLSEPAGPSEPPG 836 Query: 89 PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCF 128 P PA S EP P TP GS G+ + F Sbjct: 837 PPAPAGPASDTEEEEPG------PEGTPPSRGSSGEGLPF 870 Score = 34.7 bits (78), Expect = 0.30 Identities = 28/105 (26%), Positives = 34/105 (32%), Gaps = 3/105 (2%) Query: 18 DCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPA 77 D + + + R RE L G A + +A P P PP P + Sbjct: 906 DTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQ 965 Query: 78 SSPPPAGPGPG---PALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119 P P P P P P L G EPPA PA L Sbjct: 966 GVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAAL 1010 Score = 33.5 bits (75), Expect = 0.66 Identities = 32/119 (26%), Positives = 40/119 (33%), Gaps = 15/119 (12%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511 P PP R ++ G PP S E GP R+LS P G GP Sbjct: 787 PPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASD 846 Query: 512 AEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPR 570 E P G RG+ E + GN++ KP+GP PR Sbjct: 847 TEEEEPGPEG--------TPPSRGSSGEGLPFAEEGNLTI-------KQRPKPAGPPPR 890 Score = 33.1 bits (74), Expect = 0.86 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 11/90 (12%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA------AGPASSPPPAGPGPGPA 90 P +GA +GP +T P P PPGP + +GP + GP +PP G G Sbjct: 813 PKEGA---TGPRR-RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRG-SSGEG 867 Query: 91 LPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 LP + + + P TP G Sbjct: 868 LPFAEEGNLTIKQRPKPAGPPPRETPVPPG 897 Score = 32.7 bits (73), Expect = 1.1 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Query: 450 LYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPG 509 ++ +P + + PG P P A S G P PR RS+SL P G G Sbjct: 673 VFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRP--GPTEGDAE 730 Query: 510 VAAEPGTPFSIGRFATLTLQERR 532 AE ++G +ATLT + R Sbjct: 731 GEAEGPVGSTLGSYATLTRRPGR 753 Score = 30.4 bits (67), Expect = 5.6 Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 26/144 (18%) Query: 397 SGEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYR-----FGSAGQDTQF---CLWDLT 446 + + EEEEP GT + G+ LP A G++T + G ++T ++LT Sbjct: 844 ASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLT 903 Query: 447 EDVLYPHPPLARTR-----------TLPGTPGTTPPAASSSRGGEPG----PGPLPRSLS 491 E P R R TPG P S + G P P P P SL Sbjct: 904 ESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLP 963 Query: 492 RSNSLPHPAGGGKAGGPGVAAEPG 515 + +P P A P V PG Sbjct: 964 -AQGVPTPLAPSPAMQPPVPPCPG 986 Score = 30.0 bits (66), Expect = 7.3 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 19/102 (18%) Query: 36 LPGDGAARRSGPASA-QTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG-------PGP 87 LP G P+ A Q PVPP PGP S + + PPA PG Sbjct: 962 LPAQGVPTPLAPSPAMQPPVPP-----CPGPGLESSAASRWNGETEPPAAPAALLKVPGA 1016 Query: 88 GPALPAVRLSLVRLG------EPDSAGAGEPPATPAGLGSGG 123 G A V ++ +L P PP P G+ G Sbjct: 1017 GTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG 1058 >gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] Length = 1202 Score = 51.2 bits (121), Expect = 3e-06 Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 20/131 (15%) Query: 10 SGPGAAMGDC-AEIKSQFRTREGFYKLL---PGDGAARRSGPASAQTPVPPQPPQ----- 60 S PG GD E + + G Y L PG A R+ P+ TP P Sbjct: 802 SRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFAL 861 Query: 61 -------PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPP P S +GP+ PPP PGP A L EP AG EPP Sbjct: 862 RARRKGPPPPPPKRLSS--VSGPSPEPPPLDESPGPKEGATGPRRRTLSEP--AGPSEPP 917 Query: 114 ATPAGLGSGGD 124 PA G D Sbjct: 918 GPPAPAGPASD 928 Score = 38.9 bits (89), Expect = 0.016 Identities = 36/100 (36%), Positives = 40/100 (40%), Gaps = 23/100 (23%) Query: 42 ARRSGP--------ASAQTPVPPQPP-QPPPGPASASGPGAAGP--ASSPPPAGPG--PG 88 ARR GP +S P P PP PGP GA GP + PAGP PG Sbjct: 863 ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKE----GATGPRRRTLSEPAGPSEPPG 918 Query: 89 PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCF 128 P PA S EP P TP GS G+ + F Sbjct: 919 PPAPAGPASDTEEEEPG------PEGTPPSRGSSGEGLPF 952 Score = 34.7 bits (78), Expect = 0.30 Identities = 28/105 (26%), Positives = 34/105 (32%), Gaps = 3/105 (2%) Query: 18 DCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPA 77 D + + + R RE L G A + +A P P PP P + Sbjct: 988 DTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQ 1047 Query: 78 SSPPPAGPGPG---PALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119 P P P P P P L G EPPA PA L Sbjct: 1048 GVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAAL 1092 Score = 33.5 bits (75), Expect = 0.66 Identities = 32/119 (26%), Positives = 40/119 (33%), Gaps = 15/119 (12%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511 P PP R ++ G PP S E GP R+LS P G GP Sbjct: 869 PPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASD 928 Query: 512 AEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPR 570 E P G RG+ E + GN++ KP+GP PR Sbjct: 929 TEEEEPGPEG--------TPPSRGSSGEGLPFAEEGNLTI-------KQRPKPAGPPPR 972 Score = 33.1 bits (74), Expect = 0.86 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 11/90 (12%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA------AGPASSPPPAGPGPGPA 90 P +GA +GP +T P P PPGP + +GP + GP +PP G G Sbjct: 895 PKEGA---TGPRR-RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRG-SSGEG 949 Query: 91 LPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 LP + + + P TP G Sbjct: 950 LPFAEEGNLTIKQRPKPAGPPPRETPVPPG 979 Score = 32.7 bits (73), Expect = 1.1 Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%) Query: 450 LYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPG 509 ++ +P + + PG P P A S G P PR RS+SL P G G Sbjct: 755 VFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRP--GPTEGDAE 812 Query: 510 VAAEPGTPFSIGRFATLTLQERR 532 AE ++G +ATLT + R Sbjct: 813 GEAEGPVGSTLGSYATLTRRPGR 835 Score = 30.4 bits (67), Expect = 5.6 Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 26/144 (18%) Query: 397 SGEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYR-----FGSAGQDTQF---CLWDLT 446 + + EEEEP GT + G+ LP A G++T + G ++T ++LT Sbjct: 926 ASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLT 985 Query: 447 EDVLYPHPPLARTR-----------TLPGTPGTTPPAASSSRGGEPG----PGPLPRSLS 491 E P R R TPG P S + G P P P P SL Sbjct: 986 ESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLP 1045 Query: 492 RSNSLPHPAGGGKAGGPGVAAEPG 515 + +P P A P V PG Sbjct: 1046 -AQGVPTPLAPSPAMQPPVPPCPG 1068 Score = 30.0 bits (66), Expect = 7.3 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 19/102 (18%) Query: 36 LPGDGAARRSGPASA-QTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG-------PGP 87 LP G P+ A Q PVPP PGP S + + PPA PG Sbjct: 1044 LPAQGVPTPLAPSPAMQPPVPP-----CPGPGLESSAASRWNGETEPPAAPAALLKVPGA 1098 Query: 88 GPALPAVRLSLVRLG------EPDSAGAGEPPATPAGLGSGG 123 G A V ++ +L P PP P G+ G Sbjct: 1099 GTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG 1140 >gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] Length = 380 Score = 50.8 bits (120), Expect = 4e-06 Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 16/102 (15%) Query: 38 GDGAARRSGPASAQTPVPPQPPQPPPG------PASASGPGAAGPASSPPPAGPGPG--- 88 G A GP P PP P PPPG PA+A G G P + P PA GPG Sbjct: 161 GPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGG 220 Query: 89 -------PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 A+ +L V E S G P A G GG Sbjct: 221 AGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGG 262 Score = 44.7 bits (104), Expect = 3e-04 Identities = 35/105 (33%), Positives = 40/105 (38%), Gaps = 25/105 (23%) Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80 E++ Q R + G P + RR A P P PPPGP Sbjct: 137 EVEQQKRQQPG-----PSEHIERRVSNAGGPPAPPAGGPPPPPGPP-------------- 177 Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPA--TPAGLGSGG 123 PP GP P P LP + G AG G PPA PA G GG Sbjct: 178 PPPGPPPPPGLPPSGVPAAAHG----AGGGPPPAPPLPAAQGPGG 218 Score = 37.0 bits (84), Expect = 0.059 Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 15/63 (23%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA----GGGKAGGPG 509 PP PG P + PAA+ GG P P P P PA GGG AG PG Sbjct: 177 PPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAP-----------PLPAAQGPGGGGAGAPG 225 Query: 510 VAA 512 +AA Sbjct: 226 LAA 228 Score = 36.6 bits (83), Expect = 0.078 Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP-LPRSLSRSNSLPHPAGGGKAGGPGV 510 P PP T ++P P +P + +PGP + R +S + P P GG PG Sbjct: 119 PPPPALPTWSVPNGP--SPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGP 176 Query: 511 AAEPGTP 517 PG P Sbjct: 177 PPPPGPP 183 Score = 29.6 bits (65), Expect = 9.5 Identities = 51/204 (25%), Positives = 70/204 (34%), Gaps = 21/204 (10%) Query: 371 VNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSA-----GGAPLSPLPKAG 425 V V ++ T + A G G +E+ AAG SA GG P P P Sbjct: 67 VRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPPP-PALP 125 Query: 426 SITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSR---GGEPG 482 + + G + ++ + + P P R + G P A G P Sbjct: 126 TWSVPNGPSPEEVE------QQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPP 179 Query: 483 PGPLPRSLSRSNSLP---HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKE 539 PGP P + +P H AGGG P + A G P G A K Sbjct: 180 PGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQG-PGGGGAGAPGLAAAIAGAKLRKV 238 Query: 540 HKRYHSLG--NISRGGSGGSGSGG 561 K+ + G + SG SG GG Sbjct: 239 SKQEEASGGPTAPKAESGRSGGGG 262 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 50.4 bits (119), Expect = 5e-06 Identities = 37/120 (30%), Positives = 45/120 (37%), Gaps = 19/120 (15%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASG--------PGAAGPASSPPPAGPGPG 88 PG GP + P P PPGPA A+G PG G P P GP Sbjct: 1215 PGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGA 1274 Query: 89 PALPAVRLSLVRL-GEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGCCRRGSQR 147 P P + S+ L GEP G PP P G G + +PGC + Q+ Sbjct: 1275 PGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYK----------GFPGCDGKDGQK 1324 Score = 42.4 bits (98), Expect = 0.001 Identities = 30/94 (31%), Positives = 31/94 (32%), Gaps = 12/94 (12%) Query: 36 LPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA------AGPASSPPPAGPGPGP 89 LPG R P P PP PP PP P PG GP P P GP P Sbjct: 1280 LPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFP 1339 Query: 90 ALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P + G P G P P G G Sbjct: 1340 GPPGEK------GLPGPPGRKGPTGLPGPRGEPG 1367 Score = 40.8 bits (94), Expect = 0.004 Identities = 46/186 (24%), Positives = 63/186 (33%), Gaps = 30/186 (16%) Query: 390 AGADGERSGEEEEEEPEAA-GTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448 +G DG R + + +P + G G P SP FG++G+ Sbjct: 1062 SGIDGARGPKGNKGDPASHFGPPGPKGEPGSP-----GCPGHFGASGEQGL--------- 1107 Query: 449 VLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGP 508 P + R PG PG P SS G PG +P + + P G G P Sbjct: 1108 -----PGIQGPRGSPGRPG---PPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDP 1159 Query: 509 GVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNIS-------RGGSGGSGSGG 561 G+ PG G L + + K H +G +G G GS G Sbjct: 1160 GIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPG 1219 Query: 562 EKPSGP 567 P GP Sbjct: 1220 ISPPGP 1225 Score = 38.9 bits (89), Expect = 0.016 Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 6/70 (8%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPG----PGPLPRSLSRSNSLPHPAGGGKAGG 507 P L R PG+PG +PP +G G PG PGP + +P P G G Sbjct: 1206 PGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGP 1265 Query: 508 PGVAAEPGTP 517 PG G P Sbjct: 1266 PGPDGPRGAP 1275 Score = 37.0 bits (84), Expect = 0.059 Identities = 31/95 (32%), Positives = 34/95 (35%), Gaps = 15/95 (15%) Query: 33 YKLLPG-DGAARRSGPASAQTPVPPQPPQPPPGPASASG-PGAAGPASSPPPAG-PGPG- 88 YK PG DG + GP P P PPG G PG GP P P G PGP Sbjct: 1311 YKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPA 1370 Query: 89 -----------PALPAVRLSLVRLGEPDSAGAGEP 112 P P +R +G P G P Sbjct: 1371 DVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGP 1405 Score = 36.2 bits (82), Expect = 0.10 Identities = 36/122 (29%), Positives = 40/122 (32%), Gaps = 17/122 (13%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDG--AARRSGPASAQTPVPPQPPQPP 62 G G GP G + R + +PG + R P P P P P Sbjct: 789 GCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSP 848 Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122 P PG GP P PAG P LP G P GA PP P G Sbjct: 849 GAPGGKGQPGDVGP---PGPAGMKGLPGLP---------GRP---GAHGPPGLPGIPGPF 893 Query: 123 GD 124 GD Sbjct: 894 GD 895 Score = 35.0 bits (79), Expect = 0.23 Identities = 52/200 (26%), Positives = 63/200 (31%), Gaps = 71/200 (35%) Query: 390 AGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDV 449 AG G+ + E+ G G G PL P KAG + G G Sbjct: 592 AGEKGDPGPPGDHEDATPGGKGFPG--PLGPPGKAGPV----GPPGLG------------ 633 Query: 450 LYPHPPLARTRT-LPGTPGTTPPAASSSRGGE--------PG----PG----PLPRSLSR 492 +P PP R +PG PG P + G+ PG PG P P+ Sbjct: 634 -FPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPG 692 Query: 493 SNSLPHPAGG----GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGN 548 P +G G+ G PG A PG P Sbjct: 693 PQGAPGLSGSDGHKGRPGTPGTAEIPGPPGF----------------------------- 723 Query: 549 ISRGGSGGSGSGGEKPSGPV 568 RG G G GGEK S PV Sbjct: 724 --RGDMGDPGFGGEKGSSPV 741 Score = 35.0 bits (79), Expect = 0.23 Identities = 35/129 (27%), Positives = 42/129 (32%), Gaps = 3/129 (2%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522 PG PG P G PGP LP S+ P G G PG PG P G Sbjct: 1257 PGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG--EPGDCGLPGPPGPPGPPGPPGYKGF 1314 Query: 523 FATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTA 582 ++ + H G G G G K +P R +P Sbjct: 1315 PGCDGKDGQKGPVGFPGPQGPHGFPG-PPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVD 1373 Query: 583 LCPRIHEVP 591 CPRI +P Sbjct: 1374 DCPRIPGLP 1382 Score = 33.5 bits (75), Expect = 0.66 Identities = 28/87 (32%), Positives = 32/87 (36%), Gaps = 18/87 (20%) Query: 55 PPQPPQPP-----PGPASASG----PGAAGPASSP----PPAGPGP-----GPALPAVRL 96 PP P P PG ASG PG GP SP PP GP +P +R Sbjct: 1083 PPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRG 1142 Query: 97 SLVRLGEPDSAGAGEPPATPAGLGSGG 123 +G+P G P P G G Sbjct: 1143 QPGEMGDPGPRGLQGDPGIPGPPGIKG 1169 Score = 33.5 bits (75), Expect = 0.66 Identities = 34/104 (32%), Positives = 36/104 (34%), Gaps = 23/104 (22%) Query: 5 GAEGGSGPGAAMGDCAEIKSQ-----FRTREGFYKLLPGDGAARRSGPASAQTP------ 53 G G GP A + DC I R EG L G SGP P Sbjct: 1361 GPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGL---PGMRGPSGPGCKGEPGLDGRR 1417 Query: 54 -VPPQPPQP-PPGPASASG-------PGAAGPASSPPPAGPGPG 88 V P P PPG +G PG GP P P G GPG Sbjct: 1418 GVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPG 1461 Score = 33.1 bits (74), Expect = 0.86 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 23/84 (27%) Query: 63 PGPASASG----PGAAGP----------ASSPPPAGPGPGPALPAVRLS---------LV 99 PGP G PG GP A P P GP P LP + S L Sbjct: 465 PGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLG 524 Query: 100 RLGEPDSAGAGEPPATPAGLGSGG 123 G+P GA PP P G+ G Sbjct: 525 TKGDPGPPGAEGPPGLPGKHGASG 548 Score = 33.1 bits (74), Expect = 0.86 Identities = 37/128 (28%), Positives = 40/128 (31%), Gaps = 19/128 (14%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 G G GP G F +G L DG R G TP + P PP Sbjct: 677 GPPGFDGPPGPKG--------FPGPQGAPGLSGSDGHKGRPG-----TPGTAEIPGPPGF 723 Query: 65 PASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEP-----PATPAGL 119 PG G S P PGP P P V G+P G P P Sbjct: 724 RGDMGDPGFGGEKGSSPVGPPGP-PGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782 Query: 120 GSGGDRVC 127 G GD C Sbjct: 783 GPRGDPGC 790 Score = 33.1 bits (74), Expect = 0.86 Identities = 33/106 (31%), Positives = 38/106 (35%), Gaps = 15/106 (14%) Query: 411 GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTP 470 G G +P+ P GS G GQ + D + H R L G PG Sbjct: 734 GEKGSSPVGPPGPPGSP----GVNGQK------GIPGDPAFGHLGPPGKRGLSGVPGIKG 783 Query: 471 PAASSSRGGEPGPGPLPRSLSRSNSLPHPAG-GGKAGGPGVAAEPG 515 P G GP +P L L P G G AG PGV PG Sbjct: 784 PRGDPGCPGAEGPAGIPGFL----GLKGPKGREGHAGFPGVPGPPG 825 Score = 33.1 bits (74), Expect = 0.86 Identities = 47/168 (27%), Positives = 51/168 (30%), Gaps = 51/168 (30%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTRE-GFYKLLPGDGAARRSGPASAQTPVPPQPPQPP- 62 G G G GD Q R E G Y G R P P PP PP PP Sbjct: 978 GPPGDDGFPGERGDKGTPGMQGRRGEPGRY----GPPGFHRGEPGEKGQPGPPGPPGPPG 1033 Query: 63 ----------------------PGPASASG-PGAAGPASS---------PP-----PAGP 85 PGP SG GA GP + PP P P Sbjct: 1034 STGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093 Query: 86 G-PG-------PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125 G PG LP ++ G P G+ PP P G G R Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLR 1141 Score = 32.7 bits (73), Expect = 1.1 Identities = 29/99 (29%), Positives = 33/99 (33%), Gaps = 19/99 (19%) Query: 36 LPGDGAARRSGPASAQTPVPPQPPQPPPGPASASG----------PGAAGPASSPPPAGP 85 +P G+ GP Q P+ P PGP SG PGAAG P G Sbjct: 58 VPEKGSRGPPGPPGPQGPIGPLGA---PGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGV 114 Query: 86 GPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124 P L + G P G P GS GD Sbjct: 115 PGFPGLDGIP------GHPGPPGPRGKPGMSGHNGSRGD 147 Score = 32.3 bits (72), Expect = 1.5 Identities = 23/68 (33%), Positives = 27/68 (39%), Gaps = 6/68 (8%) Query: 62 PPGPASASGPGAAGPASSPPPAGP--GPG----PALPAVRLSLVRLGEPDSAGAGEPPAT 115 PPG SG GA G P GP PG P P ++ L +G+P G P Sbjct: 286 PPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGD 345 Query: 116 PAGLGSGG 123 P G G Sbjct: 346 PGNRGHPG 353 Score = 32.3 bits (72), Expect = 1.5 Identities = 21/54 (38%), Positives = 21/54 (38%), Gaps = 2/54 (3%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG-GGKAGGPGVAAEPG 515 PG PG P G PGP PR L P G G G PG EPG Sbjct: 884 PGLPGIPGPFGDDGLPGPPGPKG-PRGLPGFPGFPGERGKPGAEGCPGAKGEPG 936 Score = 32.3 bits (72), Expect = 1.5 Identities = 26/77 (33%), Positives = 28/77 (36%), Gaps = 14/77 (18%) Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLP-HPAGGGKAG--- 506 +P PP + LPG PG P GEPGP R LP P G G Sbjct: 1338 FPGPP--GEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMG 1395 Query: 507 --------GPGVAAEPG 515 GPG EPG Sbjct: 1396 LPGMRGPSGPGCKGEPG 1412 Score = 32.0 bits (71), Expect = 1.9 Identities = 37/126 (29%), Positives = 40/126 (31%), Gaps = 18/126 (14%) Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA-----AEPGT 516 LPG PG S GG GP P P G G PGV +PG Sbjct: 194 LPGLPG------SWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGE 247 Query: 517 PFSIGRFATLTLQERRDRGAEKEHKRYHSL-------GNISRGGSGGSGSGGEKPSGPVP 569 G L E D K K + G R G G G+ GEK P Sbjct: 248 VGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFP 307 Query: 570 RSRLDP 575 R DP Sbjct: 308 GPRGDP 313 Score = 31.2 bits (69), Expect = 3.3 Identities = 37/139 (26%), Positives = 43/139 (30%), Gaps = 13/139 (9%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG----DGAARRSGPASAQTPVPPQPPQ 60 GA G G A GD + + E PG G+ R G A + P Sbjct: 545 GASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDH 604 Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 P PG GP P GP PG P G P G P G Sbjct: 605 EDATPGGKGFPGPLGPPGKAGPVGP-PGLGFPGPPGERGHPGVPGHPGVRGPDGLK---G 660 Query: 121 SGGDRVCFNLGRELYFYPG 139 GD + N+ YPG Sbjct: 661 QKGDTISCNV-----TYPG 674 Score = 30.8 bits (68), Expect = 4.3 Identities = 28/96 (29%), Positives = 32/96 (33%), Gaps = 10/96 (10%) Query: 40 GAARRSGPASAQTPVPPQPPQPP-----PGPASASG-----PGAAGPASSPPPAGPGPGP 89 G R G A A PP P P PG A G PG G SP G Sbjct: 391 GLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQ 450 Query: 90 ALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125 LP + +G P G P G G G++ Sbjct: 451 GLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEK 486 Score = 30.8 bits (68), Expect = 4.3 Identities = 32/112 (28%), Positives = 39/112 (34%), Gaps = 10/112 (8%) Query: 459 TRTLPGTPGTT-PPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515 T+ PG PG PP G G PG + S H G G PG +PG Sbjct: 525 TKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPG 584 Query: 516 TPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567 + G E+ D G +H+ G G G G G P GP Sbjct: 585 SHGRDGHAG-----EKGDPGPPGDHEDATPGGKGFPGPLGPPGKAG--PVGP 629 Score = 30.8 bits (68), Expect = 4.3 Identities = 21/62 (33%), Positives = 24/62 (38%), Gaps = 5/62 (8%) Query: 462 LPGTPGTTPPAASSSRGGEPG-PGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSI 520 +PG G P G PG PGP S R P G+ G PG PG P Sbjct: 799 IPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGA----PGIPGQPGLPGYPGSPGAPGGK 854 Query: 521 GR 522 G+ Sbjct: 855 GQ 856 Score = 30.8 bits (68), Expect = 4.3 Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 7/60 (11%) Query: 463 PGTPGTTPPAASSSRG-----GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG PG PP S RG G+PG P S P G G G+ PG P Sbjct: 818 PGVPG--PPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLP 875 Score = 30.8 bits (68), Expect = 4.3 Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 18/78 (23%) Query: 463 PGTPGTT-PPAASSSRG-----------GEPGPGPLPRSLSRSNSLPHPAG-----GGKA 505 PG PG PP ++ RG GEPG P P S + P G Sbjct: 1023 PGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPG-SPGPPGFSGIDGARGPKGNKGDPASHF 1081 Query: 506 GGPGVAAEPGTPFSIGRF 523 G PG EPG+P G F Sbjct: 1082 GPPGPKGEPGSPGCPGHF 1099 Score = 30.0 bits (66), Expect = 7.3 Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 4/66 (6%) Query: 59 PQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSA-GAGEPPATPA 117 P PPG G AG P P G P LP + G PDSA G P +P Sbjct: 386 PPGPPGLLGRPGEACAGMIGPPGPQG---FPGLPGLPGEAGIPGRPDSAPGKPGKPGSPG 442 Query: 118 GLGSGG 123 G+ G Sbjct: 443 LPGAPG 448 Score = 30.0 bits (66), Expect = 7.3 Identities = 30/94 (31%), Positives = 34/94 (36%), Gaps = 8/94 (8%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQP----PPGPASASGP-GAAGPASSPPPAGPGPGPAL 91 PGD GPA + +P P +P PPG GP G G P P GP P Sbjct: 857 PGDVGP--PGPAGMKG-LPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGF 913 Query: 92 PAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125 P + G GA P G GDR Sbjct: 914 PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDR 947 Score = 29.6 bits (65), Expect = 9.5 Identities = 42/138 (30%), Positives = 47/138 (34%), Gaps = 30/138 (21%) Query: 452 PHPPLAR-TRTLPGTPGTT----PPAASSSRGGEPGPG-------PLPRSLSRSNSLPHP 499 P PP + R LPG PG P A G + PG P R L + P Sbjct: 899 PGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGP 958 Query: 500 AGG----------GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI 549 G G G PG + G P G T +Q RR E RY G Sbjct: 959 PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRG-----EPGRYGPPG-F 1012 Query: 550 SRGGSGGSGSGGEKPSGP 567 RG G G G P GP Sbjct: 1013 HRGEPGEKGQPG--PPGP 1028 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 50.1 bits (118), Expect = 7e-06 Identities = 44/127 (34%), Positives = 45/127 (35%), Gaps = 33/127 (25%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62 A GA G +GP A G GAA R GP P P P Sbjct: 861 AKGARGSAGPPGATGF--------------------PGAAGRVGPPGPSGNAGPPGPPGP 900 Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEP---PATPAG 118 G GP G GPA P GP PGP PA GE S GA P P TP Sbjct: 901 AGKEGGKGPRGETGPAGRPGEVGP-PGPPGPA--------GEKGSPGADGPAGAPGTPGP 951 Query: 119 LGSGGDR 125 G G R Sbjct: 952 QGIAGQR 958 Score = 44.7 bits (104), Expect = 3e-04 Identities = 45/142 (31%), Positives = 49/142 (34%), Gaps = 22/142 (15%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPVPPQPPQP-- 61 G G GP A GD E + PGD G GPA P P QP Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP-PGADGQPGA 825 Query: 62 --PPGPASASG----PGAAGPASSPPPAGPGPGPALPAVRLS------------LVRLGE 103 PG A A G PG AGPA P P G P R S R+G Sbjct: 826 KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885 Query: 104 PDSAGAGEPPATPAGLGSGGDR 125 P +G PP P G G + Sbjct: 886 PGPSGNAGPPGPPGPAGKEGGK 907 Score = 43.9 bits (102), Expect = 5e-04 Identities = 38/111 (34%), Positives = 43/111 (38%), Gaps = 24/111 (21%) Query: 5 GAEGGSGPGAAMGDCAEIKSQ----FRTREGFYKLL--PGD-GAARRSGPASAQTPVPPQ 57 GA G +GP GD E Q + GF L PG G+ GP+ A P P+ Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141 Query: 58 PPQPP------------PGPASASGP----GAAGPASSPPPAGPGPGPALP 92 P PGP GP G AGP P P GP PGP P Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGP-PGPPGP 1191 Score = 43.1 bits (100), Expect = 8e-04 Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 23/127 (18%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 GA G +GP G GF + G A GP ++ P + PPG Sbjct: 326 GATGAAGPPGPTGPAGP--------PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPG 377 Query: 65 PASASGPGAAGPASSPPPAGPG----PG----PALPAVRLSLVRLGEPDSAGAGEPPATP 116 PA A+GP A P + P G PG P P R G G G PP Sbjct: 378 PAGAAGP-AGNPGADGQPGAKGANGAPGIAGAPGFPGAR------GPSGPQGPGGPPGPK 430 Query: 117 AGLGSGG 123 G G Sbjct: 431 GNSGEPG 437 Score = 42.7 bits (99), Expect = 0.001 Identities = 55/187 (29%), Positives = 70/187 (37%), Gaps = 27/187 (14%) Query: 391 GADGERSGEEEEEEPEAAGT----GSAG--GAPLSPLPKAGSITYRFGSAGQDTQFCLWD 444 G GER G P A G G AG G+P PK G AG+ Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSP-----GEAGRPG------ 530 Query: 445 LTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGK 504 E L L + PG G T P + + G PGP P + ++ + P G Sbjct: 531 --EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGA 588 Query: 505 AGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK- 563 AG PG A E G P G A + + GA+ G RG G +GS G + Sbjct: 589 AGEPGKAGERGVPGPPG--AVGPAGKDGEAGAQGPPGPAGPAG--ERGEQGPAGSPGFQG 644 Query: 564 ---PSGP 567 P+GP Sbjct: 645 LPGPAGP 651 Score = 41.6 bits (96), Expect = 0.002 Identities = 37/137 (27%), Positives = 46/137 (33%), Gaps = 16/137 (11%) Query: 381 TRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQF 440 T A+ G G EE + A G G P P + G + F A Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA------ 498 Query: 441 CLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA 500 + V P P G+PG P S G PG LP + + S P Sbjct: 499 ------DGVAGPKGPAGER----GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548 Query: 501 GGGKAGGPGVAAEPGTP 517 GK G PG A + G P Sbjct: 549 PDGKTGPPGPAGQDGRP 565 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 6/125 (4%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQPPP 63 GA G GP G + + E + LPG G + GP+ A P P PP Sbjct: 944 GAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003 Query: 64 GPASASGPGAAGPASSPPPAG-PG--PGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 G A PG +G +P G PG P R G P + GA P G Sbjct: 1004 GLAGP--PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAG 1061 Query: 121 SGGDR 125 GDR Sbjct: 1062 KSGDR 1066 Score = 41.2 bits (95), Expect = 0.003 Identities = 43/142 (30%), Positives = 48/142 (33%), Gaps = 28/142 (19%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-------------DGAARRSGPASAQ 51 GA+G +G A G Q E LPG DG+ + G Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766 Query: 52 TPVPPQPPQPPPGPASASGP----------GAAGPASSPPPAGPGPGPALPAVRLSLVRL 101 P+ P P PG SGP GA G P P GP P Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826 Query: 102 GEPDSAG----AGEP-PATPAG 118 GEP AG AG P PA PAG Sbjct: 827 GEPGDAGAKGDAGPPGPAGPAG 848 Score = 40.4 bits (93), Expect = 0.005 Identities = 43/129 (33%), Positives = 49/129 (37%), Gaps = 18/129 (13%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRG---GEPGP-GPL-------PRSLSRSNSLPHPAG- 501 P A R +PG PG PA G PGP GP P LP PAG Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651 Query: 502 GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNIS-RGGSGGSGSG 560 G+AG PG E G P +G A R +RG E G RG +G G+ Sbjct: 652 PGEAGKPG---EQGVPGDLG--APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGND 706 Query: 561 GEKPSGPVP 569 G K P Sbjct: 707 GAKGDAGAP 715 Score = 39.3 bits (90), Expect = 0.012 Identities = 33/116 (28%), Positives = 36/116 (31%), Gaps = 37/116 (31%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPP---------------------------PGPASAS 69 P R P P PP PP PP PGP S Sbjct: 125 PAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS 184 Query: 70 GP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124 GP G GP +P P G P P GEP ++G P P G GD Sbjct: 185 GPRGLPGPPGAPGPQGFQGPPGEP---------GEPGASGPMGPRGPPGPPGKNGD 231 Score = 39.3 bits (90), Expect = 0.012 Identities = 36/130 (27%), Positives = 44/130 (33%), Gaps = 20/130 (15%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQ----------TP 53 GA+G +GP G+ + + LPG+ G GPA A+ P Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334 Query: 54 VPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113 P P PP P + G AGP GP P G P AGA P Sbjct: 335 GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEP---------GPPGPAGAAGPA 385 Query: 114 ATPAGLGSGG 123 P G G Sbjct: 386 GNPGADGQPG 395 Score = 39.3 bits (90), Expect = 0.012 Identities = 40/129 (31%), Positives = 48/129 (37%), Gaps = 29/129 (22%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 G G +GP G +EG G G +GPA V P P PG Sbjct: 887 GPSGNAGPPGPPGPAG--------KEG------GKGPRGETGPAGRPGEVGPPGP---PG 929 Query: 65 PASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRL-------GEPDSAGAGEPPATP 116 PA G PGA GPA +P PGP A + +V L G P G P Sbjct: 930 PAGEKGSPGADGPAGAPGT----PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985 Query: 117 AGLGSGGDR 125 G+ G+R Sbjct: 986 GPSGASGER 994 Score = 38.9 bits (89), Expect = 0.016 Identities = 41/132 (31%), Positives = 46/132 (34%), Gaps = 21/132 (15%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQ-------TPVP- 55 G +G GP G+ E + + K PG G GPA + P P Sbjct: 419 GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPT 478 Query: 56 --PQPPQPPPGPASASGPGAAGPASSPPPAGP--GPGPALPAVRLSLVRLGEPDSAGAGE 111 P PP GP S PGA G A PAG PGPA P G P AG Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPK--------GSPGEAGRPG 530 Query: 112 PPATPAGLGSGG 123 P G G Sbjct: 531 EAGLPGAKGLTG 542 Score = 38.1 bits (87), Expect = 0.027 Identities = 39/117 (33%), Positives = 42/117 (35%), Gaps = 30/117 (25%) Query: 37 PG-DGAARRSGPASAQTPVPPQPPQPP-----------PGPASASG-------------P 71 PG DG GPA P PP PP PGP A+G P Sbjct: 547 PGPDGKTGPPGPAGQDGR--PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604 Query: 72 GAAGPASSPPPAGP--GPGPALPA-VRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125 GA GPA AG PGPA PA R G P G P P G G++ Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661 Score = 37.7 bits (86), Expect = 0.035 Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 7/88 (7%) Query: 43 RRSGPASAQTPVPPQPPQPPPGPASASGP-GAAGPASSPP------PAGPGPGPALPAVR 95 + +G S P+ P P+ PGP A GP G GP P P GP P P Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKN 229 Query: 96 LSLVRLGEPDSAGAGEPPATPAGLGSGG 123 G+P G PP G G Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGARGLPG 257 Score = 37.7 bits (86), Expect = 0.035 Identities = 39/125 (31%), Positives = 45/125 (36%), Gaps = 17/125 (13%) Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62 G G GP A G A + + GF L DGA +GPA P P Sbjct: 242 GERGPPGPQGARGLPGTAGLPGM-KGHRGFSGL---DGAKGDAGPAG--------PKGEP 289 Query: 63 PGPASASGPGAAGPASSPPPAG-PG-PGPALPAVRLSLV-RLGEPDSAGAGEPPATPAGL 119 P PG GP P G PG PGPA G P G PP P + Sbjct: 290 GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349 Query: 120 GSGGD 124 G+ G+ Sbjct: 350 GAKGE 354 Score = 37.7 bits (86), Expect = 0.035 Identities = 40/118 (33%), Positives = 43/118 (36%), Gaps = 7/118 (5%) Query: 5 GAEGGSGPGAAMGD---CAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61 GA+G GP G E + E LPG R GP S P Sbjct: 446 GAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP-PGERGGPGSRGFP-GADGVAG 503 Query: 62 PPGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAG 118 P GPA G PG AGP SP AG LP + G P G PP PAG Sbjct: 504 PKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG-PAG 560 Score = 35.0 bits (79), Expect = 0.23 Identities = 33/111 (29%), Positives = 41/111 (36%), Gaps = 8/111 (7%) Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519 R LPG PG P GEPG P + P GK G G A +PG P Sbjct: 187 RGLPGPPGAPGPQGFQGPPGEPGE---PGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE 243 Query: 520 ---IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567 G L K H+ + L ++G +G +G GE P P Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDG-AKGDAGPAGPKGE-PGSP 292 Score = 35.0 bits (79), Expect = 0.23 Identities = 46/132 (34%), Positives = 49/132 (37%), Gaps = 36/132 (27%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQ-TPVPPQP--PQ 60 G G GP A G + GF PG GAA G A + P PP P Sbjct: 563 GRPGPPGPPGARGQAGVM--------GF----PGPKGAAGEPGKAGERGVPGPPGAVGPA 610 Query: 61 PPPGPASASGP-GAAGPASS---PPPAG-PG----PGPALPAVRLSLVRLGEPDSAGAGE 111 G A A GP G AGPA PAG PG PGPA G P AG Sbjct: 611 GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA-----------GPPGEAGKPG 659 Query: 112 PPATPAGLGSGG 123 P LG+ G Sbjct: 660 EQGVPGDLGAPG 671 Score = 34.7 bits (78), Expect = 0.30 Identities = 43/140 (30%), Positives = 51/140 (36%), Gaps = 34/140 (24%) Query: 391 GADGERSGEEEEEEPEAAGT----GSAGGA-PLSPLPKAGSITYRF--GSAGQDTQFCLW 443 GADG+ + E + A G G AG A P P+ G+ + GSAG Sbjct: 818 GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAG-------- 869 Query: 444 DLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGP-GPLPRSLSRSNSLPHPAGG 502 PP A PG G P S G PGP GP + + P G Sbjct: 870 ----------PPGATG--FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG-----PRGE 912 Query: 503 -GKAGGPGVAAEPGTPFSIG 521 G AG PG PG P G Sbjct: 913 TGPAGRPGEVGPPGPPGPAG 932 Score = 33.9 bits (76), Expect = 0.50 Identities = 36/106 (33%), Positives = 41/106 (38%), Gaps = 25/106 (23%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG-GKAGGPGVAAEPGTPFSIG 521 PG PG PA S GE GP PAG G G G A G G Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPA-------------GPAGPVGPVGARGPAGPQGPRGDKG 1097 Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK-PSG 566 E+ DRG K H+ + L +G G GS GE+ PSG Sbjct: 1098 ETG-----EQGDRGI-KGHRGFSGL----QGPPGPPGSPGEQGPSG 1133 Score = 33.1 bits (74), Expect = 0.86 Identities = 30/104 (28%), Positives = 33/104 (31%), Gaps = 26/104 (25%) Query: 46 GPASAQTPVPPQPPQPPPG----PASASGPGAAGPASSPPPAGPG--------------- 86 GP P P+ P PPG P PG GP P P G G Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171 Query: 87 ------PGPALPAVRLSLV-RLGEPDSAGAGEPPATPAGLGSGG 123 PGP P+ L G P G PP P G+ G Sbjct: 172 TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG 215 Score = 33.1 bits (74), Expect = 0.86 Identities = 39/133 (29%), Positives = 44/133 (33%), Gaps = 32/133 (24%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG----PASAQTPVPPQPPQ 60 GA+G +GP G+ R G G A R G P + P P Sbjct: 497 GADGVAGPKGPAGE--------RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548 Query: 61 P-----PPGPASASGPGAAGPASSPPPAGPG-----PGPALPAVRLSLVRLGEPDSAGAG 110 P PPGPA G GP P G PGP A GEP AG Sbjct: 549 PDGKTGPPGPAGQDG--RPGPPGPPGARGQAGVMGFPGPKGAA--------GEPGKAGER 598 Query: 111 EPPATPAGLGSGG 123 P P +G G Sbjct: 599 GVPGPPGAVGPAG 611 Score = 32.7 bits (73), Expect = 1.1 Identities = 19/53 (35%), Positives = 21/53 (39%), Gaps = 9/53 (16%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515 PG PG P+ GG PGP + NS P G G G EPG Sbjct: 409 PGFPGARGPSGPQGPGGPPGP--------KGNS-GEPGAPGSKGDTGAKGEPG 452 Score = 32.7 bits (73), Expect = 1.1 Identities = 35/110 (31%), Positives = 42/110 (38%), Gaps = 16/110 (14%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG-GGKAGGPGVAAEPGTPFSIGR 522 G PG P+ +S G PGP P L P G G+ G PG PG S G Sbjct: 980 GEPGKQGPSGASGERGPPGPMGPP-------GLAGPPGESGREGAPGAEGSPGRDGSPG- 1031 Query: 523 FATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK----PSGPV 568 A E G + G + G +G SG GE P+GPV Sbjct: 1032 -AKGDRGETGPAGPPGAPGAPGAPGPV--GPAGKSGDRGETGPAGPAGPV 1078 Score = 32.0 bits (71), Expect = 1.9 Identities = 25/93 (26%), Positives = 33/93 (35%), Gaps = 7/93 (7%) Query: 39 DGAARRSGPASAQTPVPPQPPQPPPGPASASG-------PGAAGPASSPPPAGPGPGPAL 91 DG A + G + P PQ + PG A G G G PAGP P Sbjct: 232 DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291 Query: 92 PAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124 P + ++G G P P G+ G+ Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324 Score = 32.0 bits (71), Expect = 1.9 Identities = 17/58 (29%), Positives = 21/58 (36%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 G G+ P G PGP + P G G PG+A PG P + G Sbjct: 359 GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416 Score = 32.0 bits (71), Expect = 1.9 Identities = 35/129 (27%), Positives = 43/129 (33%), Gaps = 26/129 (20%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPVPPQPPQPPP 63 G +G GP G+ + Q +PGD GA SG + + Q PP Sbjct: 641 GFQGLPGPAGPPGEAGKPGEQG---------VPGDLGAPGPSGARGERGFPGERGVQGPP 691 Query: 64 GPASASGP-------GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATP 116 GPA G GA G A +P G P L G P GA P Sbjct: 692 GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ---------GMPGERGAAGLPGPK 742 Query: 117 AGLGSGGDR 125 G G + Sbjct: 743 GDRGDAGPK 751 Score = 32.0 bits (71), Expect = 1.9 Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 12/67 (17%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRS--NSLPHPAG----------GGKAGGPGV 510 PG+PG P+ +S G GP + + N LP P G G G PG Sbjct: 1123 PGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGP 1182 Query: 511 AAEPGTP 517 PG P Sbjct: 1183 PGPPGPP 1189 Score = 31.6 bits (70), Expect = 2.5 Identities = 30/114 (26%), Positives = 33/114 (28%), Gaps = 2/114 (1%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522 PG PG A G+PG P P G AG PG G P + G Sbjct: 805 PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG- 863 Query: 523 FATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPA 576 A + G R G G G K G PR PA Sbjct: 864 -ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916 Score = 31.2 bits (69), Expect = 3.3 Identities = 35/101 (34%), Positives = 39/101 (38%), Gaps = 13/101 (12%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRT-REGF--YKLLPG-DGAARRSGPASAQTPV-PPQPP 59 GA G GP MG + REG + PG DG+ G P PP P Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048 Query: 60 QPP--PGPASASGP----GAAGPASSPPPAGP--GPGPALP 92 P PGP +G G GPA P GP GPA P Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP 1089 Score = 30.8 bits (68), Expect = 4.3 Identities = 58/214 (27%), Positives = 69/214 (32%), Gaps = 49/214 (22%) Query: 391 GADGERSGEEEEEEPEAAGT-GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDV 449 G++G + E P AG G AG P A G AG Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA------------- 408 Query: 450 LYPHPPLARTRTLPGTPGTTP--------PAASSSRG-----GEPG-------PGPLPRS 489 P P AR + P PG P P A S+G GEPG PGP Sbjct: 409 --PGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466 Query: 490 LSR-SNSLPHPAG----GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYH 544 R + P P G G+ GGPG PG G +RG+ Sbjct: 467 GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG-----PKGPAGERGSPGPAGPKG 521 Query: 545 SLGNISRGGSGG-SGSGG--EKPSGPVPRSRLDP 575 S G R G G G+ G P P P + P Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGP 555 Score = 30.4 bits (67), Expect = 5.6 Identities = 36/124 (29%), Positives = 45/124 (36%), Gaps = 37/124 (29%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG-------GKAGGP---GVAA 512 PG+PG + G+ GP LP R + P PAG G AG P G A Sbjct: 289 PGSPG------ENGAPGQMGPRGLPGERGRPGA-PGPAGARGNDGATGAAGPPGPTGPAG 341 Query: 513 EPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSR 572 PG P ++G + + G + RG G G GE P P P Sbjct: 342 PPGFPGAVG--------AKGEAGPQG-----------PRGSEGPQGVRGE-PGPPGPAGA 381 Query: 573 LDPA 576 PA Sbjct: 382 AGPA 385 Score = 30.4 bits (67), Expect = 5.6 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 23/120 (19%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG-GKAGGPGVAAEPGTPFSIG 521 PG G PA G+PG +P L P P+G G+ G PG G P G Sbjct: 640 PGFQGLPGPAGPPGEAGKPGEQGVPGDL----GAPGPSGARGERGFPGERGVQGPPGPAG 695 Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNI-------SRGGSGGSGSGGEKPSGPVPRSRLD 574 RGA + G+ S+G G G GE+ + +P + D Sbjct: 696 -----------PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744 Score = 30.4 bits (67), Expect = 5.6 Identities = 18/58 (31%), Positives = 20/58 (34%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 G+PG + G PGP P S G G PG EPG P G Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812 Score = 30.4 bits (67), Expect = 5.6 Identities = 36/131 (27%), Positives = 38/131 (29%), Gaps = 55/131 (41%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62 A GA G GP GD E +GPA PV P + P Sbjct: 1050 APGAPGPVGPAGKSGDRGE-----------------------TGPAGPAGPVGPVGARGP 1086 Query: 63 PGPASASG----------------------PGAAGPASSPPPAGP--GPGPALPAVRLSL 98 GP G G GP SP GP GPA P Sbjct: 1087 AGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR----- 1141 Query: 99 VRLGEPDSAGA 109 G P SAGA Sbjct: 1142 ---GPPGSAGA 1149 Score = 30.4 bits (67), Expect = 5.6 Identities = 21/64 (32%), Positives = 23/64 (35%), Gaps = 9/64 (14%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRS-----NSLPHPAG----GGKAGGPGVAAE 513 PG PG+ S G GP P S N LP P G G+ G G Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP 1179 Query: 514 PGTP 517 PG P Sbjct: 1180 PGPP 1183 Score = 29.6 bits (65), Expect = 9.5 Identities = 24/76 (31%), Positives = 25/76 (32%), Gaps = 16/76 (21%) Query: 462 LPGTPGTTPPAASSSRGGEPGPG---------------PLPRSLSRSNSLPHPAGG-GKA 505 LPG PG P GG P P P S LP P G G Sbjct: 140 LPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQ 199 Query: 506 GGPGVAAEPGTPFSIG 521 G G EPG P + G Sbjct: 200 GFQGPPGEPGEPGASG 215 >gi|39812378 RAN binding protein 9 [Homo sapiens] Length = 729 Score = 50.1 bits (118), Expect = 7e-06 Identities = 28/66 (42%), Positives = 32/66 (48%), Gaps = 5/66 (7%) Query: 47 PASAQTPVPPQPPQPPPGPASASGPGAAGP-----ASSPPPAGPGPGPALPAVRLSLVRL 101 P T PP PP PPP PASA+ P + P A+ P PAG P PAL A + Sbjct: 74 PPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPF 133 Query: 102 GEPDSA 107 DSA Sbjct: 134 PHGDSA 139 Score = 34.3 bits (77), Expect = 0.39 Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 17/70 (24%) Query: 57 QPPQPPPGPASASGPGAAGPASSPPPAGPGP--GPALPAVRLSLVRLGEPDSAGAGEPPA 114 QPP PPP S PPPA P G LPA P + AG PA Sbjct: 4 QPPPPPPQQQQQQ-----QQLSPPPPAALAPVSGVVLPA----------PPAVSAGSSPA 48 Query: 115 TPAGLGSGGD 124 G G+GG+ Sbjct: 49 GSPGGGAGGE 58 Score = 33.5 bits (75), Expect = 0.66 Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 449 VLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGP 508 +L+P PP P P PP +S+ GP P P L+ P PAGG Sbjct: 68 LLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGP-PAPPGLAAG---PGPAGGAPTPAL 123 Query: 509 GVAAEPGTPFSIGRFATLTLQER 531 + PF G A L QE+ Sbjct: 124 VAGSSAAAPFPHGDSA-LNEQEK 145 Score = 32.7 bits (73), Expect = 1.1 Identities = 28/85 (32%), Positives = 29/85 (34%), Gaps = 24/85 (28%) Query: 53 PVPP------QPPQPPPGPASASGPGAAG------PASSPPPAGPGPGPALPAVRLSLVR 100 P PP P P G A G GAA P PPPA P P P Sbjct: 36 PAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPP------- 88 Query: 101 LGEPDSAGAGEP---PATPAGLGSG 122 P A A P P P GL +G Sbjct: 89 --PPPPASAAAPASGPPAPPGLAAG 111 Score = 30.4 bits (67), Expect = 5.6 Identities = 25/82 (30%), Positives = 27/82 (32%), Gaps = 20/82 (24%) Query: 55 PPQPPQ----------PPPG----------PASASGPGAAGPASSPPPAGPGPGPALPAV 94 PP PPQ PPP PA + + PA SP G G A Sbjct: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65 Query: 95 RLSLVRLGEPDSAGAGEPPATP 116 L L P A A PP P Sbjct: 66 ALLLHPPPPPPPATAAPPPPPP 87 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 50.1 bits (118), Expect = 7e-06 Identities = 36/90 (40%), Positives = 39/90 (43%), Gaps = 11/90 (12%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG------PGPGPA 90 P A R PA+A PP P PPP PA + AA PA +P A P PGPA Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVA---AAAPARAPRAAAAAATAPPSPGPA 165 Query: 91 LPAVRLS-LVRLGEPDSAGAGEPP-ATPAG 118 P R L P A A P A PAG Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195 Score = 42.7 bits (99), Expect = 0.001 Identities = 30/82 (36%), Positives = 36/82 (43%), Gaps = 15/82 (18%) Query: 42 ARRSGPASAQTPVPPQPPQPPP-----GPASASGPGAAGPASSPPPAGP--GPGPALPAV 94 A R+ A+A P P P QP P P +A P A P + PPAGP P PA+ A Sbjct: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAA- 206 Query: 95 RLSLVRLGEPDSAGAGEPPATP 116 EP +PPA P Sbjct: 207 -------REPPLPPPPQPPAPP 221 Score = 42.0 bits (97), Expect = 0.002 Identities = 34/106 (32%), Positives = 43/106 (40%), Gaps = 7/106 (6%) Query: 27 RTREGFYKLLPGDGAARRS--GPASAQTPVPPQPPQ----PPPGPASASGPGAAGPASSP 80 RTR KL+ R S G S + QPP+ PP P + G AA A++P Sbjct: 68 RTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAP 127 Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT-PAGLGSGGDR 125 PP P P P + R +A A PP+ PA G R Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQR 173 Score = 39.3 bits (90), Expect = 0.012 Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 7/75 (9%) Query: 42 ARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRL 101 AR A+A PP P PGP + A P ++PPPA P P R Sbjct: 146 ARAPRAAAAAATAPPSPGPAQPGPRAQ----RAAPLAAPPPAPAAPPAVAPPAG---PRR 198 Query: 102 GEPDSAGAGEPPATP 116 P + A EPP P Sbjct: 199 APPPAVAAREPPLPP 213 Score = 33.9 bits (76), Expect = 0.50 Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALP 92 P G A+ GP + + PP P P + + P AGP +PPPA P LP Sbjct: 160 PSPGPAQ-PGPRAQRAAPLAAPPPAPAAPPAVAPP--AGPRRAPPPAVAAREPPLP 212 Score = 33.1 bits (74), Expect = 0.86 Identities = 27/76 (35%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG---PGPGPALPA 93 P G R PA A P PP PP P P P PPP G G A P Sbjct: 192 PPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQP--PPPQPQPPPEGGAVRAGGAARPV 249 Query: 94 VRLSLVR-LGEPDSAG 108 +VR LG AG Sbjct: 250 SLREVVRYLGGSGGAG 265 Score = 31.2 bits (69), Expect = 3.3 Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 9/64 (14%) Query: 41 AARRSGPASAQTPVPPQPPQPPPGPASAS---------GPGAAGPASSPPPAGPGPGPAL 91 AA PA+ PP P+ P PA A+ P A PPP P P P Sbjct: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEG 237 Query: 92 PAVR 95 AVR Sbjct: 238 GAVR 241 >gi|134142824 forkhead box D2 [Homo sapiens] Length = 495 Score = 49.7 bits (117), Expect = 9e-06 Identities = 37/85 (43%), Positives = 45/85 (52%), Gaps = 7/85 (8%) Query: 42 ARRSGPASAQTPVPP-QPPQPPPGPASASGPGAAGPASSPPPA---GPGPGPA-LPAVRL 96 A + A Q VPP + PPPGP +AS AG A +P PA GPGPGPA LPA Sbjct: 298 AAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAFLG 357 Query: 97 SLVRLGEPDSAGAGEPPA--TPAGL 119 + + + A + PPA T AGL Sbjct: 358 AELGCAKAFYAASLSPPAAGTAAGL 382 Score = 35.8 bits (81), Expect = 0.13 Identities = 45/172 (26%), Positives = 55/172 (31%), Gaps = 19/172 (11%) Query: 407 AAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTP 466 A G G AP P P + + +A Q + P PP A G Sbjct: 276 AYGAPPPGPAP-HPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASV--FAGAG 332 Query: 467 GTTPPAASSSRGGEPGPGPLPRSLSR---------SNSLPHPAGGGKAGGPGVAAEPGTP 517 PA +S G PGP LP L + SL PA G AG P G Sbjct: 333 SAPAPAPASGSGPGPGPAGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLK 392 Query: 518 FSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569 G A GA + S+ +I G GG+ G P P Sbjct: 393 TDAGGGA-------GGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGP 437 Score = 34.7 bits (78), Expect = 0.30 Identities = 34/121 (28%), Positives = 41/121 (33%), Gaps = 38/121 (31%) Query: 39 DGAARRSGPASAQTPVPPQPPQPPPGP--------ASASGPGA----------------- 73 +G+ R + P+PP P P P P A+A PGA Sbjct: 213 NGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGL 272 Query: 74 AGPASSPPPAGPGPGP--------ALPAVRLSLVRLGEPDSAGAGEPPATP-----AGLG 120 A PA PP GP P P A + +L P A PP P AG G Sbjct: 273 ALPAYGAPPPGPAPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAG 332 Query: 121 S 121 S Sbjct: 333 S 333 Score = 33.9 bits (76), Expect = 0.50 Identities = 35/121 (28%), Positives = 41/121 (33%), Gaps = 23/121 (19%) Query: 4 GGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPP 63 GGA PGA + A + G+ LP GA P P P P P Sbjct: 245 GGAAAAGDPGAFLPGFAAYGAY---GYGYGLALPAYGAP---------PPGPAPHPHPHP 292 Query: 64 GPASASGPGAAGPA--SSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGS 121 + + AA P S PP P P P + AGAG PA GS Sbjct: 293 HAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASV---------FAGAGSAPAPAPASGS 343 Query: 122 G 122 G Sbjct: 344 G 344 Score = 31.2 bits (69), Expect = 3.3 Identities = 12/22 (54%), Positives = 14/22 (63%) Query: 63 PGPASASGPGAAGPASSPPPAG 84 PGP +A+ GAAGP PP G Sbjct: 97 PGPGAAAARGAAGPGPGPPSGG 118 Score = 30.0 bits (66), Expect = 7.3 Identities = 13/26 (50%), Positives = 17/26 (65%) Query: 64 GPASASGPGAAGPASSPPPAGPGPGP 89 G A+A+G G A++ AGPGPGP Sbjct: 89 GAAAAAGSPGPGAAAARGAAGPGPGP 114 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 49.7 bits (117), Expect = 9e-06 Identities = 38/117 (32%), Positives = 50/117 (42%), Gaps = 15/117 (12%) Query: 20 AEIKSQFRTREGFYKLLPGDGAARRSGPASAQTP----VPPQPPQPPPGPASASGPGAAG 75 AE +SQ + +E + ++++ P + P PP P PP GP A G Sbjct: 366 AEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPG 425 Query: 76 PASSPPPAGPGPG-------PALPAVRLSLVRL---GEPDSAGAGEPPATPAGLGSG 122 P + PP GP PG P +P +R L RL G P G PP P GL G Sbjct: 426 PPTGLPP-GPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPG 481 Score = 40.8 bits (94), Expect = 0.004 Identities = 27/68 (39%), Positives = 29/68 (42%), Gaps = 4/68 (5%) Query: 53 PVPPQPPQPPPGPASASGPGA---AGPASSPPPAGPGPGPALPA-VRLSLVRLGEPDSAG 108 P P +PP PPPGP PG P PPPA PG P P +R LV P G Sbjct: 462 PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPG 521 Query: 109 AGEPPATP 116 P P Sbjct: 522 LFPPAPLP 529 Score = 34.3 bits (77), Expect = 0.39 Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 4/66 (6%) Query: 37 PGDGAARRSGPASAQTPVPPQPPQ-PPPGPASASGPGAAGPASSPPPAGPGPG-PALPAV 94 PG R P PP P PPPGP PG P PPP P P P +P Sbjct: 445 PGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGP--PPRGPPPRLPPPAPPGIPPP 502 Query: 95 RLSLVR 100 R ++R Sbjct: 503 RPGMMR 508 Score = 32.0 bits (71), Expect = 1.9 Identities = 23/65 (35%), Positives = 25/65 (38%), Gaps = 5/65 (7%) Query: 64 GPASASGPGAAGPASSPP-----PAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAG 118 G ++AS A P S PP P PGP P P L G P G PP P Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPF 441 Query: 119 LGSGG 123 L G Sbjct: 442 LRPPG 446 >gi|26665869 WD repeat domain 51B [Homo sapiens] Length = 478 Score = 49.7 bits (117), Expect = 9e-06 Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 4/120 (3%) Query: 274 RNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVC 333 R +++ P+ FS DG+ LA S+D ++V+ + + + C Sbjct: 92 RGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAK 151 Query: 334 WSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGAD 393 +SPDGR +V+ ED + +W T + V + N V F+P T +AG+D Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGT----CIASAGSD 207 Score = 48.1 bits (113), Expect = 3e-05 Identities = 27/87 (31%), Positives = 41/87 (47%) Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVT 351 FSP G LA S+D +R++ D K++ + V +S DG+++ T ED + Sbjct: 68 FSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIK 127 Query: 352 VWSFTEGRVVARGHGHKSWVNAVAFDP 378 VWS R + + H WV F P Sbjct: 128 VWSMYRQRFLYSLYRHTHWVRCAKFSP 154 Score = 48.1 bits (113), Expect = 3e-05 Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 8/161 (4%) Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVT 351 FSPDGR + S+D ++++ + G V ++P G + + G D V Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 211 Query: 352 VWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGE-RSGEEEEEEPEAAGT 410 VW +++ H VN ++F P + A +DG + + E Sbjct: 212 VWDVRVNKLLQHYQVHSGGVNCISFHP----SGNYLITASSDGTLKILDLLEGRLIYTLQ 267 Query: 411 GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLY 451 G G K G + F S G DTQ LW D L+ Sbjct: 268 GHTGPVFTVSFSKGGEL---FASGGADTQVLLWRTNFDELH 305 Score = 47.4 bits (111), Expect = 4e-05 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%) Query: 285 GPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTG 344 G N F+P G +A D ++V+ L + + GG+ C+ + P G Y++T Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA 246 Query: 345 GEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGAD 393 D + + EGR++ GH V V+F ++ E + GAD Sbjct: 247 SSDGTLKILDLLEGRLIYTLQGHTGPVFTVSF----SKGGELFASGGAD 291 Score = 40.4 bits (93), Expect = 0.005 Identities = 22/77 (28%), Positives = 35/77 (45%) Query: 277 LAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSP 336 L + V G +N +F P G +L S DG L++ L ++ + G + V +S Sbjct: 221 LQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSK 280 Query: 337 DGRYVVTGGEDDLVTVW 353 G +GG D V +W Sbjct: 281 GGELFASGGADTQVLLW 297 Score = 33.9 bits (76), Expect = 0.50 Identities = 17/63 (26%), Positives = 29/63 (46%) Query: 317 LLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAF 376 +L K + + + SP+G+ + T D + +W+F R GHK V +V F Sbjct: 9 VLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQF 68 Query: 377 DPY 379 P+ Sbjct: 69 SPH 71 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 49.3 bits (116), Expect = 1e-05 Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 4/115 (3%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPVPPQPPQPPP 63 G+ G GP GD E + ++ PG+ GA GPA Q + P P Sbjct: 1080 GSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR 1139 Query: 64 GPASASG-PGAAGPASSPPPAGPGPGP-ALPAVRLSLVRLGEPDSAGAGEPPATP 116 GP SG PG G + P P GP PGP R S G P G PP P Sbjct: 1140 GPVGPSGPPGKDGTSGHPGPIGP-PGPRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193 Score = 47.8 bits (112), Expect = 3e-05 Identities = 40/127 (31%), Positives = 48/127 (37%), Gaps = 12/127 (9%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG-PASAQTPVPPQPPQPPP 63 G+ G GP C + + Y + G +G P A P PP PP Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG 189 Query: 64 GPASASGPGAAGPASSPPPAGP-GP-------GPALPAVR-LSLVRLGEPDSAGAGEPPA 114 P S PG GP P AGP GP GP+ PA + R G P G PP Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG 249 Query: 115 T--PAGL 119 PAG+ Sbjct: 250 IKGPAGI 256 Score = 44.7 bits (104), Expect = 3e-04 Identities = 42/122 (34%), Positives = 48/122 (39%), Gaps = 16/122 (13%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 G GGSGP G +K + R G G GAA P + P PP P Sbjct: 843 GPPGGSGPAGPPGPQG-VKGE-RGSPG------GPGAA--GFPGARGLPGPPGSNGNPGP 892 Query: 65 PASASGPGAAGPASSPPPAGPGPGPALPAV---RLSLVRLGEPDSAGAGEPPATPAGLGS 121 P + PG GP P PAG P P V + + GE S GA PP P LG Sbjct: 893 PGPSGSPGKDGP---PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949 Query: 122 GG 123 G Sbjct: 950 AG 951 Score = 41.6 bits (96), Expect = 0.002 Identities = 47/154 (30%), Positives = 51/154 (33%), Gaps = 47/154 (30%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPA--SAQTPVPPQPPQPP 62 GA G GP A G+ R R G LPG AR + A S P PP PP Sbjct: 294 GAPGPMGPRGAPGE--------RGRPG----LPGAAGARGNDGARGSDGQPGPPGPPGTA 341 Query: 63 PGPASASGPGAAGPASSP----------------------PPAGPG----------PGPA 90 P S G GPA SP PP PG GPA Sbjct: 342 GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401 Query: 91 -LPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 +P + G P AGA P G G G Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435 Score = 40.8 bits (94), Expect = 0.004 Identities = 58/200 (29%), Positives = 67/200 (33%), Gaps = 31/200 (15%) Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSP-LPKAGSITYRFGSAGQDTQFCLWDLTE 447 A G GE E P G A G P LP A G+ G D Q Sbjct: 280 APGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQ-------- 331 Query: 448 DVLYPHPP-LARTRTLPGTPGT---TPPAASSSRGGEPGP--GPLPRSLSRSNSLPHPAG 501 P PP T PG+PG PA S G PG P P+ + + P P G Sbjct: 332 ----PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387 Query: 502 -GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSG 560 G GG G G P + G RG + G RGG+G G Sbjct: 388 INGSPGGKGEMGPAGIPGAPGLMGA--------RGPPGPAGANGAPG--LRGGAGEPGKN 437 Query: 561 GEKPSGPVPRSRLDPAKVLG 580 G K P PR A + G Sbjct: 438 GAK-GEPGPRGERGEAGIPG 456 Score = 40.8 bits (94), Expect = 0.004 Identities = 38/134 (28%), Positives = 49/134 (36%), Gaps = 27/134 (20%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGF-----YKLLPGD----GAARRSGPASAQ---- 51 GA G +GP A G+ R+G + +PG G+ + GP +Q Sbjct: 510 GAPGPAGPRGAAGEPG--------RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561 Query: 52 TPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111 P PP P P P PG G +P G GP P + G P G Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ------GPPGKNGETG 615 Query: 112 PPATPAGLGSGGDR 125 P P G GGD+ Sbjct: 616 PQGPPGPTGPGGDK 629 Score = 40.4 bits (93), Expect = 0.005 Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 17/121 (14%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP-PP 63 G G +GPG GD Q + LPG G GP +P +P P Sbjct: 618 GPPGPTGPGGDKGDTGPPGPQG------LQGLPGTG-----GPPGENG----KPGEPGPK 662 Query: 64 GPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122 G A A G PG G A +P GP P +R G GA PP P G+ Sbjct: 663 GDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTP 722 Query: 123 G 123 G Sbjct: 723 G 723 Score = 40.4 bits (93), Expect = 0.005 Identities = 31/95 (32%), Positives = 34/95 (35%), Gaps = 10/95 (10%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGP-------ASASGPGAAGPASS---PPPAGPGPGP 89 G GP P P PPGP S GPGAAG + P P G P Sbjct: 831 GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890 Query: 90 ALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124 P S + G P AG P +P G GD Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD 925 Score = 39.7 bits (91), Expect = 0.009 Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 6/91 (6%) Query: 38 GDGAARRSG-PASAQTPVPPQPPQPPPGPASASGP----GAAGPASSPPPAGPGPGPALP 92 G G +G P + P P PP P GPA SG G AGPA +P PAG P Sbjct: 1030 GKGDRGENGSPGAPGAPGHPGPPGPV-GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ 1088 Query: 93 AVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 R GE +AG P G+ G Sbjct: 1089 GPRGDKGETGERGAAGIKGHRGFPGNPGAPG 1119 Score = 39.3 bits (90), Expect = 0.012 Identities = 45/146 (30%), Positives = 53/146 (36%), Gaps = 24/146 (16%) Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448 A G +GE G+ E P G GG P P GS G AG + + Sbjct: 814 APGQNGEPGGKGERGAP---GEKGEGGPPGVAGPPGGS-----GPAGPPGP---QGVKGE 862 Query: 449 VLYPHPPLAR----TRTLPGTPGTT----PPAASSSRGGEPGPGP-----LPRSLSRSNS 495 P P A R LPG PG+ PP S S G + PGP P S S Sbjct: 863 RGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922 Query: 496 LPHPAGGGKAGGPGVAAEPGTPFSIG 521 G+ G PG PG P +G Sbjct: 923 KGDAGQPGEKGSPGAQGPPGAPGPLG 948 Score = 38.9 bits (89), Expect = 0.016 Identities = 57/204 (27%), Positives = 67/204 (32%), Gaps = 51/204 (25%) Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445 A A G G+ E P AG G P P+ G G+AG Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK-----GAAGP--------- 712 Query: 446 TEDVLYPHPP-LARTRTLPGTPGTT----PPAASSSRGGEPGPGPL-------PRSLSRS 493 P PP A T L G PG P +G GPG PR + Sbjct: 713 ------PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGP 766 Query: 494 NSLPHPAG-------GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSL 546 P PAG GG G PG+A G+P ER + G + Sbjct: 767 IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP-----------GERGETGPPGPAGFPGAP 815 Query: 547 G-NISRGGSGGSGSGGEKPSGPVP 569 G N GG G G+ GEK G P Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPP 839 Score = 38.9 bits (89), Expect = 0.016 Identities = 34/121 (28%), Positives = 40/121 (33%), Gaps = 9/121 (7%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 GA G GP A G ++ R G P GP + P G Sbjct: 708 GAAGPPGPPGAAGTPG-LQGMPGERGGLGSPGPKGDKGEPGGPGADGVP-------GKDG 759 Query: 65 PASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P +GP G GPA P G G P LP + GE G P P G G Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819 Query: 124 D 124 + Sbjct: 820 E 820 Score = 38.9 bits (89), Expect = 0.016 Identities = 32/119 (26%), Positives = 38/119 (31%), Gaps = 1/119 (0%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 G +G GP +G EG LPG A R P PP P P Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI-AGPRGSPGERGETGPPGPAGFPGA 814 Query: 65 PASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P PG G +P G G P + G P G +P G G+ G Sbjct: 815 PGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG 873 Score = 38.9 bits (89), Expect = 0.016 Identities = 44/147 (29%), Positives = 56/147 (38%), Gaps = 40/147 (27%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62 A GA G GP +G KS R G G A GPA ++ PQ P+ Sbjct: 1042 APGAPGHPGPPGPVGPAG--KSGDRGESG------PAGPAGAPGPAGSRGAPGPQGPRGD 1093 Query: 63 PG----------------PASASGPGAAGPA------SSPPPAGP-GP-GPALPAVRLSL 98 G P + PG+ GPA SP PAGP GP GP+ P Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP----- 1148 Query: 99 VRLGEPDSAGAGEPPATPAGLGSGGDR 125 G+ ++G P P G+ G+R Sbjct: 1149 ---GKDGTSGHPGPIGPPGPRGNRGER 1172 Score = 38.5 bits (88), Expect = 0.020 Identities = 52/203 (25%), Positives = 66/203 (32%), Gaps = 35/203 (17%) Query: 387 ATAAGADGERSGEEEEEEPEAAGT----GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCL 442 A A GA G R G E + A G G G A + +P A + GS G+ L Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL 478 Query: 443 WDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG 502 P A R PG G P G G P + P Sbjct: 479 -----------PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527 Query: 503 GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNIS------------ 550 G GGPG+ PG+P G + G++ E R G Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDG-----KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582 Query: 551 -RGGSGGSGSGGEK--PSGPVPR 570 +G G G GE+ P GP P+ Sbjct: 583 PKGNDGAPGKNGERGGPGGPGPQ 605 Score = 38.1 bits (87), Expect = 0.027 Identities = 39/140 (27%), Positives = 46/140 (32%), Gaps = 35/140 (25%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPV--------- 54 GA G G GD + PG+ G+ GP A P+ Sbjct: 912 GAPGSPGVSGPKGDAGQ---------------PGEKGSPGAQGPPGAPGPLGIAGITGAR 956 Query: 55 ----PPQPPQP--PPGPASASG----PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEP 104 PP P P PGP G PGA G + P GP P L R G P Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016 Query: 105 DSAGAGEPPATPAGLGSGGD 124 S G +P G G G+ Sbjct: 1017 GSDGLPGRDGSPGGKGDRGE 1036 Score = 37.4 bits (85), Expect = 0.046 Identities = 27/90 (30%), Positives = 27/90 (30%), Gaps = 13/90 (14%) Query: 38 GDGAARRSGPASAQTPVPPQPPQPPPGPASASG----PGAAGPASSPPPAGPGPGPALPA 93 G G GP PQ P P GP G PG G P GP P Sbjct: 598 GPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP- 656 Query: 94 VRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 GEP G P P G G G Sbjct: 657 --------GEPGPKGDAGAPGAPGGKGDAG 678 Score = 37.0 bits (84), Expect = 0.059 Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 30/118 (25%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPG 509 P PP A TR PP +G G+PGP +P G+ G PG Sbjct: 89 PQPPTAPTR---------PPNGQGPQGPKGDPGPPGIP---------------GRNGDPG 124 Query: 510 VAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567 + +PG+P S G + E G + +Y S ++ G + G +G P+GP Sbjct: 125 IPGQPGSPGSPG---PPGICESCPTGPQNYSPQYDSY-DVKSGVAVGGLAGYPGPAGP 178 Score = 36.6 bits (83), Expect = 0.078 Identities = 53/203 (26%), Positives = 71/203 (34%), Gaps = 43/203 (21%) Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAP-----LSPLPKAGSITYRFGSAGQDTQF 440 AA A G DG R + + P GT G+P + P GS G+ GQ + Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS----NGAPGQRGE- 370 Query: 441 CLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPH 498 P G PG PP + S G GE GP +P + + Sbjct: 371 -------------PGPQGHAGAQGPPG--PPGINGSPGGKGEMGPAGIPGAPGLMGARGP 415 Query: 499 PAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDR-------GAEKEHKRYHSLGNISR 551 P G G PG+ G P G + R GA+ E + S G Sbjct: 416 PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPG--EP 473 Query: 552 GGSGGSGSGGEK-------PSGP 567 G +G G+ GE+ P+GP Sbjct: 474 GANGLPGAAGERGAPGFRGPAGP 496 Score = 36.2 bits (82), Expect = 0.10 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 6/54 (11%) Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515 L G PGT P + + GEPGP + + P G G AG PG PG Sbjct: 640 LQGLPGTGGPPGENGKPGEPGPK------GDAGAPGAPGGKGDAGAPGERGPPG 687 Score = 35.4 bits (80), Expect = 0.17 Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 14/63 (22%) Query: 54 VPPQPPQPPPGPASASGPGAAGPASSP-PPAGPGPG--PALPAVRLSLVRLGEPDSAGAG 110 V PQPP P P + GP GP P PP PG P +P G+P S G+ Sbjct: 87 VCPQPPTAPTRPPNGQGP--QGPKGDPGPPGIPGRNGDPGIP---------GQPGSPGSP 135 Query: 111 EPP 113 PP Sbjct: 136 GPP 138 Score = 35.4 bits (80), Expect = 0.17 Identities = 36/127 (28%), Positives = 43/127 (33%), Gaps = 8/127 (6%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-------GAARRSGPASAQTPVPPQ 57 GA+G GP G+ E PG+ GAA G + P P Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497 Query: 58 PPQPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATP 116 GPA G PG AGP + G P P +R G P S G PP + Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557 Query: 117 AGLGSGG 123 G G Sbjct: 558 GESGRPG 564 Score = 35.0 bits (79), Expect = 0.23 Identities = 37/125 (29%), Positives = 44/125 (35%), Gaps = 13/125 (10%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVL 450 G+ G + + E P A G G P P G G AGQ D E Sbjct: 735 GSPGPKGDKGEPGGPGADGVPGKDG-PRGPTGPIGPP----GPAGQPG-----DKGEGGA 784 Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 P +A R PG G T P + G PG P + P G+ G PGV Sbjct: 785 PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGA---PGEKGEGGPPGV 841 Query: 511 AAEPG 515 A PG Sbjct: 842 AGPPG 846 Score = 35.0 bits (79), Expect = 0.23 Identities = 34/109 (31%), Positives = 38/109 (34%), Gaps = 10/109 (9%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PG P + G PGP P + P G G PG E G P G F Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG-F 811 Query: 524 ATLTLQE-----RRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567 Q + +RGA E G G GGSG G P GP Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPG--VAGPPGGSGPAG--PPGP 856 Score = 35.0 bits (79), Expect = 0.23 Identities = 52/184 (28%), Positives = 60/184 (32%), Gaps = 35/184 (19%) Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448 A G GER + P AGT G +P + + R GS G D E+ Sbjct: 985 ANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP--GSDGLPGRDGSPGGKG-----DRGEN 1037 Query: 449 VLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGP 508 P P A PG PG PA S GE GP G AG P Sbjct: 1038 GS-PGAPGAPGH--PGPPGPVGPAGKSGDRGESGP------------------AGPAGAP 1076 Query: 509 GVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGS-----GGEK 563 G A G P G R K H+ + GN GS G G Sbjct: 1077 GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP--GNPGAPGSPGPAGQQGAIGSPG 1134 Query: 564 PSGP 567 P+GP Sbjct: 1135 PAGP 1138 Score = 34.7 bits (78), Expect = 0.30 Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 18/120 (15%) Query: 415 GAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDV----LYPHPPLARTRTLPGTPGTT- 469 G+P SP P + G Q+ +D+ V L +P A PG PGT+ Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG 189 Query: 470 PPAASSSRG-----GEPG-------PGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 P + S G GEPG PGP P ++ S G+ G PG PG P Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPSGPAGKDGESGRPGRPGERGLPGPP 248 Score = 34.7 bits (78), Expect = 0.30 Identities = 34/118 (28%), Positives = 40/118 (33%), Gaps = 10/118 (8%) Query: 463 PGTPGTTPPAASSSRGGEPGP-GPL-PRSLSRSNSLPHPAGG-------GKAGGPGVAAE 513 PG+ G P S G PGP GP PR P P G G+ GGPG Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604 Query: 514 PGTPFSIGRFATLTLQERRDRGAEK-EHKRYHSLGNISRGGSGGSGSGGEKPSGPVPR 570 G P G G +K + G G+GG KP P P+ Sbjct: 605 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662 Score = 34.3 bits (77), Expect = 0.39 Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 17/130 (13%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAP----LSPLPKAGSITYRFGSAGQDTQFCLWDLT 446 G GE+ E P AG A G P + P + G G D + Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK------- 550 Query: 447 EDVLYPHPPLARTRT-LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKA 505 P PP ++ + PG PG + P G PGP + ++ P G G Sbjct: 551 -----PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605 Query: 506 GGPGVAAEPG 515 G PG E G Sbjct: 606 GPPGKNGETG 615 Score = 33.5 bits (75), Expect = 0.66 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 8/61 (13%) Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122 PGPA G GP P +G P P + GEP AG PP P +G Sbjct: 173 PGPA-----GPPGPPGPPGTSGHPGSPGSPGYQ---GPPGEPGQAGPSGPPGPPGAIGPS 224 Query: 123 G 123 G Sbjct: 225 G 225 Score = 33.5 bits (75), Expect = 0.66 Identities = 36/113 (31%), Positives = 37/113 (32%), Gaps = 13/113 (11%) Query: 457 ARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGT 516 A R PG G A R G PG GP R + S P GK G PG E G Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPG-GPGMRGMPGSPG--GPGSDGKPGPPGSQGESGR 562 Query: 517 PFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGG--SGSGGEKPSGP 567 P G RG GN G G G GG P GP Sbjct: 563 PGPPG--------PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP 607 Score = 33.5 bits (75), Expect = 0.66 Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 18/73 (24%) Query: 463 PGTPGTTPPAASSSRGGEPGP----GPL----PRSLSRSNSLPHPAGG----------GK 504 PG PG+ PA G PGP GP+ P ++ P P G G Sbjct: 1115 PGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGS 1174 Query: 505 AGGPGVAAEPGTP 517 G PG +PG P Sbjct: 1175 EGSPGHPGQPGPP 1187 Score = 32.0 bits (71), Expect = 1.9 Identities = 58/224 (25%), Positives = 71/224 (31%), Gaps = 47/224 (20%) Query: 378 PYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQD 437 P + A+ AG+ G + EP G A G P P I G G Sbjct: 344 PGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP-----GINGSPGGKG-- 396 Query: 438 TQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-----PLPRSLSR 492 ++ + P L R PG G GEPG P PR Sbjct: 397 ------EMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450 Query: 493 SNSLPHPAGG----GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGN 548 +P G GK G PG G P + G +RGA Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG-----------ERGAPG---------- 489 Query: 549 ISRGGSGGSGSGGEK-PSGPVPRSRLDPAKVLGTALCPRIHEVP 591 RG +G +G GEK P+G R PA G A P VP Sbjct: 490 -FRGPAGPNGIPGEKGPAG--ERGAPGPAGPRGAAGEPGRDGVP 530 Score = 32.0 bits (71), Expect = 1.9 Identities = 49/187 (26%), Positives = 61/187 (32%), Gaps = 51/187 (27%) Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKA-GSITYRFGSAGQDTQFCLWDLTE 447 A G+ G + + +P G+ A G P +P P IT G AG Sbjct: 913 APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGP----------- 961 Query: 448 DVLYPHPPLARTRTLPGTPGTT----PPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAG 501 P + R PG G P A+ G G PGP LP + + P Sbjct: 962 ------PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP---GLAGTAGEPGR 1012 Query: 502 GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGG 561 G G G+ G+P G DRG N S G G G G Sbjct: 1013 DGNPGSDGLPGRDGSPGGKG-----------DRGE-----------NGSPGAPGAPGHPG 1050 Query: 562 EKPSGPV 568 P GPV Sbjct: 1051 --PPGPV 1055 Score = 31.6 bits (70), Expect = 2.5 Identities = 35/117 (29%), Positives = 42/117 (35%), Gaps = 31/117 (26%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASG-PGAAGPASSPPPAG----PGPG------ 88 G GPA + PPGPA A+G PG G A P G PGP Sbjct: 393 GGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA 452 Query: 89 --PALPAVRLSLVRLGEPDSAGA----------GEP----PATPAGL----GSGGDR 125 P +P + + G P GA G P PA P G+ G G+R Sbjct: 453 GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER 509 Score = 31.6 bits (70), Expect = 2.5 Identities = 23/62 (37%), Positives = 24/62 (38%), Gaps = 5/62 (8%) Query: 62 PPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGS 121 PPGP G GAAGP P P G P L + LG P G P P G Sbjct: 700 PPGPEG--GKGAAGP---PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV 754 Query: 122 GG 123 G Sbjct: 755 PG 756 Score = 30.0 bits (66), Expect = 7.3 Identities = 28/95 (29%), Positives = 31/95 (32%), Gaps = 18/95 (18%) Query: 47 PASAQTPVPPQPPQPPPG-PASASGPGAAGPASSPPPAGP---------GPGPALPAVRL 96 P + Q P P+ PPG P PG G SP GP GP P Sbjct: 98 PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS 157 Query: 97 SLVR--------LGEPDSAGAGEPPATPAGLGSGG 123 V+ G P AG PP P G G Sbjct: 158 YDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPG 192 Score = 30.0 bits (66), Expect = 7.3 Identities = 24/74 (32%), Positives = 26/74 (35%), Gaps = 10/74 (13%) Query: 454 PPLARTRTLP-GTPGTTPPAASSSRGGEPGPGPL--------PRSLSRSNSLPHPAG-GG 503 PP T P G PG T P G PGP L P + P P G G Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666 Query: 504 KAGGPGVAAEPGTP 517 G PG + G P Sbjct: 667 APGAPGGKGDAGAP 680 >gi|83779014 katanin p80 subunit B 1 [Homo sapiens] Length = 655 Score = 48.9 bits (115), Expect = 2e-05 Identities = 27/90 (30%), Positives = 48/90 (53%), Gaps = 6/90 (6%) Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFG---GLLCVCWSPDGRYVVTGGEDD 348 F P G +A SQD ++++ + +G + Y G + C+ +SPDG+++ + +D Sbjct: 113 FHPYGEFVASGSQDTNIKLW---DIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDH 169 Query: 349 LVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378 V +W T G++++ GH VN V F P Sbjct: 170 TVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199 Score = 38.5 bits (88), Expect = 0.020 Identities = 18/76 (23%), Positives = 34/76 (44%) Query: 303 SQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVA 362 SQ G +RV+ ++ + + + + + + P G +V +G +D + +W V Sbjct: 82 SQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVF 141 Query: 363 RGHGHKSWVNAVAFDP 378 R GH V + F P Sbjct: 142 RYRGHSQAVRCLRFSP 157 Score = 37.7 bits (86), Expect = 0.035 Identities = 21/87 (24%), Positives = 41/87 (47%) Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVT 351 FSPDG+ LA + D ++++ + + + G + V + P+ + +G D + Sbjct: 155 FSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214 Query: 352 VWSFTEGRVVARGHGHKSWVNAVAFDP 378 W + +VV+ G V +V F+P Sbjct: 215 FWDLEKFQVVSCIEGEPGPVRSVLFNP 241 Score = 31.6 bits (70), Expect = 2.5 Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 18/114 (15%) Query: 338 GRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERS 397 GR + TGG+D V +WS + + GH S V +V + EE A G +S Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN----TPEELIVA----GSQS 84 Query: 398 GEEEEEEPEAAGT------GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445 G + EAA A L P + S QDT LWD+ Sbjct: 85 GSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFV----ASGSQDTNIKLWDI 134 Score = 31.2 bits (69), Expect = 3.3 Identities = 18/65 (27%), Positives = 32/65 (49%) Query: 285 GPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTG 344 GP+N F P+ LA S D +R + + + ++ G + V ++PDG + +G Sbjct: 190 GPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249 Query: 345 GEDDL 349 +D L Sbjct: 250 CQDSL 254 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 48.9 bits (115), Expect = 2e-05 Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62 G+ G +GP G + + + +G G A G S TPVP P PP PP Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119 PGP G PG+ G P GP P +P + G P G P T L Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720 Query: 120 GSGG 123 G G Sbjct: 721 GCPG 724 Score = 43.9 bits (102), Expect = 5e-04 Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%) Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84 K LPG G SG Q P P P P PGPA +GP GP P P Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124 PG PG A P LS+ G P G PP P LG GD Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511 P + +LPG+PG PP G GEPGP P +L P GK G PG A Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 512 AEPGTPFSIG 521 E G S G Sbjct: 1406 GEKGNKGSKG 1415 Score = 39.3 bits (90), Expect = 0.012 Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%) Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505 +P PP +PG G P S G PGP P S S+ HP G Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279 Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564 G PG A + G P +G T L R D G + GN GS G G P Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338 Query: 565 SGPVPRSRLDP 575 GP P R DP Sbjct: 1339 KGP-PGVRGDP 1348 Score = 38.5 bits (88), Expect = 0.020 Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%) Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504 PG+PG PA G GEPG PGP PR LS S +P P G G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 505 AGGPGVAAEPGTPFSIGR 522 G PG PG P S+G+ Sbjct: 664 PGHPGPQGPPGIPGSLGK 681 Score = 37.0 bits (84), Expect = 0.059 Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56 G +G G MG+ IK Q FR +Y G GP + P Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370 Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112 Q P PPG P S PG++ P P PG G R +G P S G AG P Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427 Query: 113 -PATPAGLGSGGDRV 126 P +P G GD V Sbjct: 428 LPGSPGPPGPPGDIV 442 Score = 36.2 bits (82), Expect = 0.10 Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47 A G +G SGP G + R G+ L G R G P Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426 Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88 +P PP PP + PPG G PG GP P P PGP Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486 Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P LP + G +AG P +P G G Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Score = 35.0 bits (79), Expect = 0.23 Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522 PG PG PA G PG LP L G G PG+ PG P G Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147 Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569 + ++ + R EK RG G G+ G++ + P Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200 Score = 34.3 bits (77), Expect = 0.39 Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%) Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61 A G G G A GD R GF L GA +GP P + Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225 Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPG A PG G P S P PG PG + ++ +G P G PP Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282 Query: 114 ATPAGLGSGG 123 T +G G Sbjct: 1283 GTAGDMGPPG 1292 Score = 33.9 bits (76), Expect = 0.50 Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%) Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95 R P + P P P Q PG G PG G P P GP GP P VR Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349 Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125 L ++ L GEP G PP P LG G R Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390 Score = 33.5 bits (75), Expect = 0.66 Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118 PGP + G G GP P P GP P LP + S VR G P +G+ P TP Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 119 LGSGG 123 G G Sbjct: 114 TGPYG 118 Score = 33.5 bits (75), Expect = 0.66 Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%) Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457 G + EP GT GAP P G AG P L+ Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649 Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 + +PG PG P G GP +P SL + P G+ G PG+ PG P Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705 Score = 33.1 bits (74), Expect = 0.86 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%) Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 P L + LPG G P S+ GEPG +P S+ G G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 511 AAEPGTP 517 A PG P Sbjct: 1038 AGRPGLP 1044 Score = 33.1 bits (74), Expect = 0.86 Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%) Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78 ++PG R P S +P P PP PP PGP PG AG Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289 Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P G P LP R G P G P +G G Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334 Score = 33.1 bits (74), Expect = 0.86 Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 9/80 (11%) Query: 55 PPQP--PQPPPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPD 105 PP P P+ PPG G PG+ GP +P G P P +L G Sbjct: 1332 PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG 1391 Query: 106 SAGAGEPPATPAGLGSGGDR 125 G P TP G G++ Sbjct: 1392 KPGKDGKPGTPGPAGEKGNK 1411 Score = 31.6 bits (70), Expect = 2.5 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%) Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54 G G +GP +G C+ K + +GF Y +PG + A A+ Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89 + PG A GP G GP P P GP PGP Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199 Score = 31.6 bits (70), Expect = 2.5 Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509 P P AR P P P + SSR G G PG P + P G G PG Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421 Query: 510 VAAEPGTPFSIG 521 A PG P S G Sbjct: 422 CAGSPGLPGSPG 433 Score = 31.6 bits (70), Expect = 2.5 Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%) Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 R PG PG PP G G PGP P + + S P G+ G PG Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569 E G D+G + H +G+ G G +G+ GEK + VP Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 31.6 bits (70), Expect = 2.5 Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%) Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519 R +PG PG G PGP P S +P G G PG G P S Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569 G+ TL R R H L +G G G S G +P P P Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069 Score = 31.2 bits (69), Expect = 3.3 Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%) Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435 G+ GER G++ P + G + G P SP P G I +R G G Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460 Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485 + C T+ P PP LPG PG R G G Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515 P S + P G G PG+ E G Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Score = 31.2 bits (69), Expect = 3.3 Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%) Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 +PG+ G R G PG P L P + G + G PG +PG P +G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581 + +G + LG G+ GS P P P L + G Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129 Query: 582 ALCPRIHEVP 591 P I P Sbjct: 1130 LGPPGIRGPP 1139 Score = 31.2 bits (69), Expect = 3.3 Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PGT R G PG LP P G+ G PG G P IG Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575 + R D G K S G G G G GE P P P L P Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386 Score = 30.8 bits (68), Expect = 4.3 Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG PG+ + RG PG R +++ P G AG PG+ PG P Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435 Score = 30.8 bits (68), Expect = 4.3 Identities = 20/61 (32%), Positives = 24/61 (39%), Gaps = 1/61 (1%) Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGA-GE 111 P P PP P P PG GP + P GP P + GE + G+ GE Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 112 P 112 P Sbjct: 1417 P 1417 Score = 30.4 bits (67), Expect = 5.6 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 PG PG A + GG PG P R NS H G+ G PG+ PGTP + G Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786 Score = 29.6 bits (65), Expect = 9.5 Identities = 18/55 (32%), Positives = 22/55 (40%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG G+ P G PG P +L + P G G PG+ EPG P Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 48.9 bits (115), Expect = 2e-05 Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62 G+ G +GP G + + + +G G A G S TPVP P PP PP Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119 PGP G PG+ G P GP P +P + G P G P T L Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720 Query: 120 GSGG 123 G G Sbjct: 721 GCPG 724 Score = 43.9 bits (102), Expect = 5e-04 Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%) Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84 K LPG G SG Q P P P P PGPA +GP GP P P Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124 PG PG A P LS+ G P G PP P LG GD Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511 P + +LPG+PG PP G GEPGP P +L P GK G PG A Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 512 AEPGTPFSIG 521 E G S G Sbjct: 1406 GEKGNKGSKG 1415 Score = 39.3 bits (90), Expect = 0.012 Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%) Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505 +P PP +PG G P S G PGP P S S+ HP G Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279 Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564 G PG A + G P +G T L R D G + GN GS G G P Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338 Query: 565 SGPVPRSRLDP 575 GP P R DP Sbjct: 1339 KGP-PGVRGDP 1348 Score = 38.5 bits (88), Expect = 0.020 Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%) Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504 PG+PG PA G GEPG PGP PR LS S +P P G G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 505 AGGPGVAAEPGTPFSIGR 522 G PG PG P S+G+ Sbjct: 664 PGHPGPQGPPGIPGSLGK 681 Score = 37.0 bits (84), Expect = 0.059 Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56 G +G G MG+ IK Q FR +Y G GP + P Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370 Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112 Q P PPG P S PG++ P P PG G R +G P S G AG P Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427 Query: 113 -PATPAGLGSGGDRV 126 P +P G GD V Sbjct: 428 LPGSPGPPGPPGDIV 442 Score = 36.2 bits (82), Expect = 0.10 Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47 A G +G SGP G + R G+ L G R G P Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426 Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88 +P PP PP + PPG G PG GP P P PGP Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486 Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P LP + G +AG P +P G G Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Score = 35.0 bits (79), Expect = 0.23 Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522 PG PG PA G PG LP L G G PG+ PG P G Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147 Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569 + ++ + R EK RG G G+ G++ + P Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200 Score = 34.3 bits (77), Expect = 0.39 Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%) Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61 A G G G A GD R GF L GA +GP P + Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225 Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPG A PG G P S P PG PG + ++ +G P G PP Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282 Query: 114 ATPAGLGSGG 123 T +G G Sbjct: 1283 GTAGDMGPPG 1292 Score = 33.9 bits (76), Expect = 0.50 Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%) Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95 R P + P P P Q PG G PG G P P GP GP P VR Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349 Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125 L ++ L GEP G PP P LG G R Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390 Score = 33.5 bits (75), Expect = 0.66 Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118 PGP + G G GP P P GP P LP + S VR G P +G+ P TP Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 119 LGSGG 123 G G Sbjct: 114 TGPYG 118 Score = 33.5 bits (75), Expect = 0.66 Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%) Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457 G + EP GT GAP P G AG P L+ Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649 Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 + +PG PG P G GP +P SL + P G+ G PG+ PG P Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705 Score = 33.1 bits (74), Expect = 0.86 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%) Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 P L + LPG G P S+ GEPG +P S+ G G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 511 AAEPGTP 517 A PG P Sbjct: 1038 AGRPGLP 1044 Score = 33.1 bits (74), Expect = 0.86 Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%) Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78 ++PG R P S +P P PP PP PGP PG AG Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289 Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P G P LP R G P G P +G G Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334 Score = 33.1 bits (74), Expect = 0.86 Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 13/82 (15%) Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPG-----------PGPALPAVRLSLVRL 101 P P PP P P PG GP + P GP PGPA + + Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKGNKGSK 1414 Query: 102 GEPDSAGAGEPPATPAGLGSGG 123 GEP AG+ P G G Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSG 1436 Score = 31.6 bits (70), Expect = 2.5 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%) Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54 G G +GP +G C+ K + +GF Y +PG + A A+ Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89 + PG A GP G GP P P GP PGP Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199 Score = 31.6 bits (70), Expect = 2.5 Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509 P P AR P P P + SSR G G PG P + P G G PG Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421 Query: 510 VAAEPGTPFSIG 521 A PG P S G Sbjct: 422 CAGSPGLPGSPG 433 Score = 31.6 bits (70), Expect = 2.5 Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%) Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 R PG PG PP G G PGP P + + S P G+ G PG Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569 E G D+G + H +G+ G G +G+ GEK + VP Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 31.6 bits (70), Expect = 2.5 Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%) Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519 R +PG PG G PGP P S +P G G PG G P S Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569 G+ TL R R H L +G G G S G +P P P Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069 Score = 31.2 bits (69), Expect = 3.3 Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%) Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435 G+ GER G++ P + G + G P SP P G I +R G G Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460 Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485 + C T+ P PP LPG PG R G G Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515 P S + P G G PG+ E G Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Score = 31.2 bits (69), Expect = 3.3 Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%) Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 +PG+ G R G PG P L P + G + G PG +PG P +G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581 + +G + LG G+ GS P P P L + G Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129 Query: 582 ALCPRIHEVP 591 P I P Sbjct: 1130 LGPPGIRGPP 1139 Score = 31.2 bits (69), Expect = 3.3 Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PGT R G PG LP P G+ G PG G P IG Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575 + R D G K S G G G G GE P P P L P Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386 Score = 30.8 bits (68), Expect = 4.3 Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG PG+ + RG PG R +++ P G AG PG+ PG P Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435 Score = 30.4 bits (67), Expect = 5.6 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 PG PG A + GG PG P R NS H G+ G PG+ PGTP + G Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786 Score = 29.6 bits (65), Expect = 9.5 Identities = 18/55 (32%), Positives = 22/55 (40%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG G+ P G PG P +L + P G G PG+ EPG P Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 48.9 bits (115), Expect = 2e-05 Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62 G+ G +GP G + + + +G G A G S TPVP P PP PP Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119 PGP G PG+ G P GP P +P + G P G P T L Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720 Query: 120 GSGG 123 G G Sbjct: 721 GCPG 724 Score = 43.9 bits (102), Expect = 5e-04 Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%) Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84 K LPG G SG Q P P P P PGPA +GP GP P P Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124 PG PG A P LS+ G P G PP P LG GD Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511 P + +LPG+PG PP G GEPGP P +L P GK G PG A Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 512 AEPGTPFSIG 521 E G S G Sbjct: 1406 GEKGNKGSKG 1415 Score = 39.3 bits (90), Expect = 0.012 Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%) Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505 +P PP +PG G P S G PGP P S S+ HP G Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279 Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564 G PG A + G P +G T L R D G + GN GS G G P Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338 Query: 565 SGPVPRSRLDP 575 GP P R DP Sbjct: 1339 KGP-PGVRGDP 1348 Score = 38.5 bits (88), Expect = 0.020 Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%) Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504 PG+PG PA G GEPG PGP PR LS S +P P G G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 505 AGGPGVAAEPGTPFSIGR 522 G PG PG P S+G+ Sbjct: 664 PGHPGPQGPPGIPGSLGK 681 Score = 37.0 bits (84), Expect = 0.059 Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56 G +G G MG+ IK Q FR +Y G GP + P Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370 Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112 Q P PPG P S PG++ P P PG G R +G P S G AG P Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427 Query: 113 -PATPAGLGSGGDRV 126 P +P G GD V Sbjct: 428 LPGSPGPPGPPGDIV 442 Score = 36.2 bits (82), Expect = 0.10 Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47 A G +G SGP G + R G+ L G R G P Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426 Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88 +P PP PP + PPG G PG GP P P PGP Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486 Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P LP + G +AG P +P G G Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Score = 35.0 bits (79), Expect = 0.23 Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522 PG PG PA G PG LP L G G PG+ PG P G Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147 Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569 + ++ + R EK RG G G+ G++ + P Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200 Score = 34.3 bits (77), Expect = 0.39 Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%) Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61 A G G G A GD R GF L GA +GP P + Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225 Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPG A PG G P S P PG PG + ++ +G P G PP Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282 Query: 114 ATPAGLGSGG 123 T +G G Sbjct: 1283 GTAGDMGPPG 1292 Score = 33.9 bits (76), Expect = 0.50 Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%) Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95 R P + P P P Q PG G PG G P P GP GP P VR Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349 Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125 L ++ L GEP G PP P LG G R Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390 Score = 33.5 bits (75), Expect = 0.66 Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118 PGP + G G GP P P GP P LP + S VR G P +G+ P TP Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 119 LGSGG 123 G G Sbjct: 114 TGPYG 118 Score = 33.5 bits (75), Expect = 0.66 Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%) Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457 G + EP GT GAP P G AG P L+ Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649 Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 + +PG PG P G GP +P SL + P G+ G PG+ PG P Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705 Score = 33.1 bits (74), Expect = 0.86 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%) Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 P L + LPG G P S+ GEPG +P S+ G G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 511 AAEPGTP 517 A PG P Sbjct: 1038 AGRPGLP 1044 Score = 33.1 bits (74), Expect = 0.86 Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%) Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78 ++PG R P S +P P PP PP PGP PG AG Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289 Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P G P LP R G P G P +G G Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334 Score = 33.1 bits (74), Expect = 0.86 Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 13/82 (15%) Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPG-----------PGPALPAVRLSLVRL 101 P P PP P P PG GP + P GP PGPA + + Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKGNKGSK 1414 Query: 102 GEPDSAGAGEPPATPAGLGSGG 123 GEP AG+ P G G Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSG 1436 Score = 31.6 bits (70), Expect = 2.5 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%) Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54 G G +GP +G C+ K + +GF Y +PG + A A+ Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89 + PG A GP G GP P P GP PGP Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199 Score = 31.6 bits (70), Expect = 2.5 Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509 P P AR P P P + SSR G G PG P + P G G PG Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421 Query: 510 VAAEPGTPFSIG 521 A PG P S G Sbjct: 422 CAGSPGLPGSPG 433 Score = 31.6 bits (70), Expect = 2.5 Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%) Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 R PG PG PP G G PGP P + + S P G+ G PG Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569 E G D+G + H +G+ G G +G+ GEK + VP Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 31.6 bits (70), Expect = 2.5 Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%) Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519 R +PG PG G PGP P S +P G G PG G P S Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569 G+ TL R R H L +G G G S G +P P P Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069 Score = 31.2 bits (69), Expect = 3.3 Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%) Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435 G+ GER G++ P + G + G P SP P G I +R G G Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460 Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485 + C T+ P PP LPG PG R G G Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515 P S + P G G PG+ E G Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Score = 31.2 bits (69), Expect = 3.3 Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%) Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 +PG+ G R G PG P L P + G + G PG +PG P +G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581 + +G + LG G+ GS P P P L + G Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129 Query: 582 ALCPRIHEVP 591 P I P Sbjct: 1130 LGPPGIRGPP 1139 Score = 31.2 bits (69), Expect = 3.3 Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PGT R G PG LP P G+ G PG G P IG Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575 + R D G K S G G G G GE P P P L P Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386 Score = 30.8 bits (68), Expect = 4.3 Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG PG+ + RG PG R +++ P G AG PG+ PG P Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435 Score = 30.4 bits (67), Expect = 5.6 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 PG PG A + GG PG P R NS H G+ G PG+ PGTP + G Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786 Score = 29.6 bits (65), Expect = 9.5 Identities = 18/55 (32%), Positives = 22/55 (40%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG G+ P G PG P +L + P G G PG+ EPG P Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 48.9 bits (115), Expect = 2e-05 Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62 G+ G +GP G + + + +G G A G S TPVP P PP PP Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664 Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119 PGP G PG+ G P GP P +P + G P G P T L Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720 Query: 120 GSGG 123 G G Sbjct: 721 GCPG 724 Score = 43.9 bits (102), Expect = 5e-04 Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%) Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84 K LPG G SG Q P P P P PGPA +GP GP P P Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124 PG PG A P LS+ G P G PP P LG GD Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511 P + +LPG+PG PP G GEPGP P +L P GK G PG A Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 512 AEPGTPFSIG 521 E G S G Sbjct: 1406 GEKGNKGSKG 1415 Score = 39.3 bits (90), Expect = 0.012 Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%) Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505 +P PP +PG G P S G PGP P S S+ HP G Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279 Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564 G PG A + G P +G T L R D G + GN GS G G P Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338 Query: 565 SGPVPRSRLDP 575 GP P R DP Sbjct: 1339 KGP-PGVRGDP 1348 Score = 38.5 bits (88), Expect = 0.020 Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%) Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504 PG+PG PA G GEPG PGP PR LS S +P P G G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 505 AGGPGVAAEPGTPFSIGR 522 G PG PG P S+G+ Sbjct: 664 PGHPGPQGPPGIPGSLGK 681 Score = 37.0 bits (84), Expect = 0.059 Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%) Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56 G +G G MG+ IK Q FR +Y G GP + P Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370 Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112 Q P PPG P S PG++ P P PG G R +G P S G AG P Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427 Query: 113 -PATPAGLGSGGDRV 126 P +P G GD V Sbjct: 428 LPGSPGPPGPPGDIV 442 Score = 36.2 bits (82), Expect = 0.10 Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47 A G +G SGP G + R G+ L G R G P Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426 Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88 +P PP PP + PPG G PG GP P P PGP Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486 Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P LP + G +AG P +P G G Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523 Score = 35.0 bits (79), Expect = 0.23 Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522 PG PG PA G PG LP L G G PG+ PG P G Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147 Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569 + ++ + R EK RG G G+ G++ + P Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200 Score = 34.3 bits (77), Expect = 0.39 Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%) Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61 A G G G A GD R GF L GA +GP P + Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225 Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPG A PG G P S P PG PG + ++ +G P G PP Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282 Query: 114 ATPAGLGSGG 123 T +G G Sbjct: 1283 GTAGDMGPPG 1292 Score = 33.9 bits (76), Expect = 0.50 Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%) Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95 R P + P P P Q PG G PG G P P GP GP P VR Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349 Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125 L ++ L GEP G PP P LG G R Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390 Score = 33.5 bits (75), Expect = 0.66 Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118 PGP + G G GP P P GP P LP + S VR G P +G+ P TP Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113 Query: 119 LGSGG 123 G G Sbjct: 114 TGPYG 118 Score = 33.5 bits (75), Expect = 0.66 Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%) Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457 G + EP GT GAP P G AG P L+ Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649 Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 + +PG PG P G GP +P SL + P G+ G PG+ PG P Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705 Score = 33.1 bits (74), Expect = 0.86 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%) Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 P L + LPG G P S+ GEPG +P S+ G G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 511 AAEPGTP 517 A PG P Sbjct: 1038 AGRPGLP 1044 Score = 33.1 bits (74), Expect = 0.86 Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%) Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78 ++PG R P S +P P PP PP PGP PG AG Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289 Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 P G P LP R G P G P +G G Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334 Score = 33.1 bits (74), Expect = 0.86 Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 13/82 (15%) Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPG-----------PGPALPAVRLSLVRL 101 P P PP P P PG GP + P GP PGPA + + Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKGNKGSK 1414 Query: 102 GEPDSAGAGEPPATPAGLGSGG 123 GEP AG+ P G G Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSG 1436 Score = 31.6 bits (70), Expect = 2.5 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%) Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54 G G +GP +G C+ K + +GF Y +PG + A A+ Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164 Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89 + PG A GP G GP P P GP PGP Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199 Score = 31.6 bits (70), Expect = 2.5 Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509 P P AR P P P + SSR G G PG P + P G G PG Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421 Query: 510 VAAEPGTPFSIG 521 A PG P S G Sbjct: 422 CAGSPGLPGSPG 433 Score = 31.6 bits (70), Expect = 2.5 Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%) Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510 R PG PG PP G G PGP P + + S P G+ G PG Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569 E G D+G + H +G+ G G +G+ GEK + VP Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975 Score = 31.6 bits (70), Expect = 2.5 Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%) Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519 R +PG PG G PGP P S +P G G PG G P S Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569 G+ TL R R H L +G G G S G +P P P Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069 Score = 31.2 bits (69), Expect = 3.3 Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%) Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435 G+ GER G++ P + G + G P SP P G I +R G G Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460 Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485 + C T+ P PP LPG PG R G G Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511 Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515 P S + P G G PG+ E G Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541 Score = 31.2 bits (69), Expect = 3.3 Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%) Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 +PG+ G R G PG P L P + G + G PG +PG P +G Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581 + +G + LG G+ GS P P P L + G Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129 Query: 582 ALCPRIHEVP 591 P I P Sbjct: 1130 LGPPGIRGPP 1139 Score = 31.2 bits (69), Expect = 3.3 Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PGT R G PG LP P G+ G PG G P IG Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575 + R D G K S G G G G GE P P P L P Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386 Score = 30.8 bits (68), Expect = 4.3 Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG PG+ + RG PG R +++ P G AG PG+ PG P Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435 Score = 30.4 bits (67), Expect = 5.6 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521 PG PG A + GG PG P R NS H G+ G PG+ PGTP + G Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786 Score = 29.6 bits (65), Expect = 9.5 Identities = 18/55 (32%), Positives = 22/55 (40%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PG G+ P G PG P +L + P G G PG+ EPG P Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 48.5 bits (114), Expect = 2e-05 Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 23/132 (17%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQ-FRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61 A G +G GP G+ E + + GF L G SG A P P P+ Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1164 Query: 62 PPGPASASG-------------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAG 108 PPGP SG PG G + PAGP P P G P G Sbjct: 1165 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP---------GPPGPPG 1215 Query: 109 AGEPPATPAGLG 120 G + AGLG Sbjct: 1216 PGIDMSAFAGLG 1227 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 8/86 (9%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLV 99 G A + G A A P P P GP +GP A A PP A PG A Sbjct: 852 GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA--------G 903 Query: 100 RLGEPDSAGAGEPPATPAGLGSGGDR 125 R+G P S G PP P G G + Sbjct: 904 RVGPPGSNGNPGPPGPPGPSGKDGPK 929 Score = 42.0 bits (97), Expect = 0.002 Identities = 44/141 (31%), Positives = 49/141 (34%), Gaps = 24/141 (17%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ--TPVPPQP-PQ 60 G G GP A G E + PG DG G A A P P P+ Sbjct: 378 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437 Query: 61 PPPGPASASGP----------------GAAGPASSPPPAGP--GPGPALPAVRLSLVRLG 102 PPGP A+GP G GP P PAGP PGPA + G Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--ARG 495 Query: 103 EPDSAGAGEPPATPAGLGSGG 123 EP G PP G+ G Sbjct: 496 EPGGVGPIGPPGERGAPGNRG 516 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 7/80 (8%) Query: 51 QTPVPPQPPQPPPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGE 103 Q P+ P P+ PPGPA A G PG G P GP P P G+ Sbjct: 200 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259 Query: 104 PDSAGAGEPPATPAGLGSGG 123 P AG PP G G Sbjct: 260 PGKAGERGPPGPQGARGFPG 279 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/123 (26%), Positives = 43/123 (34%), Gaps = 2/123 (1%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGA--ARRSGPASAQTPVPPQPPQPP 62 GAEG GP G + + E + LPG ++ P ++ PP P PP Sbjct: 966 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025 Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122 A PG G + P G + R +G P + G P G Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085 Query: 123 GDR 125 GDR Sbjct: 1086 GDR 1088 Score = 40.8 bits (94), Expect = 0.004 Identities = 43/120 (35%), Positives = 45/120 (37%), Gaps = 33/120 (27%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 GA G GP A G PG A R P S P PP PP G Sbjct: 885 GARGAQGPPGATG------------------FPG-AAGRVGPPGSNGNPGPPGPP----G 921 Query: 65 PASASGP-GAAGPASSPPPAG-PG-PGPALPAVRLSLVRLGEP--DSAGAGEPPATPAGL 119 P+ GP GA G + P AG PG GPA P GEP D E P P GL Sbjct: 922 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-----GEKGEPGDDGPSGAEGPPGPQGL 976 Score = 40.4 bits (93), Expect = 0.005 Identities = 38/113 (33%), Positives = 43/113 (38%), Gaps = 24/113 (21%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG----GGKAGGPGVAAEPGTPFS 519 G PG PA G PGP S LP P G GGK G GV E G P Sbjct: 642 GPPGPAGPAGERGEQGAPGP-------SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 694 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLG-NISRGGSGGSGSGGEK----PSGP 567 +G R +RG E + G RG G G+ G K P+GP Sbjct: 695 VG--------PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739 Score = 38.5 bits (88), Expect = 0.020 Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 20/130 (15%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP-- 61 GA G +GP GD E + EG PG DG +GP P + Sbjct: 756 GAAGIAGPKGDRGDVGE-----KGPEG----APGKDGGRGLTGPIGPPGPAGANGEKGEV 806 Query: 62 -PPGPASASG----PGAAGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPGPA ++G PG G P P AGP P + G+ AGA P Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866 Query: 114 ATPAGLGSGG 123 G G Sbjct: 867 GPSGAPGPQG 876 Score = 38.1 bits (87), Expect = 0.027 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 20/119 (16%) Query: 463 PGTPGTTPPAASSSRGGEPGP-GPL-PRSLSRSNSLPHPAGG----------GKAGGPGV 510 PG PG A + GE GP GP R + LP G G+AG PGV Sbjct: 248 PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 307 Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-SRGGSGGSGSGGEKPSGPV 568 E G+P G + RG E R G +RG G G G P GPV Sbjct: 308 KGESGSPGENGSPGPM-----GPRGLPGERGRTGPAGAAGARGNDGQPGPAG--PPGPV 359 Score = 38.1 bits (87), Expect = 0.027 Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 19/104 (18%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP----------GAAGPASSPPPAGPGPGP 89 G SG P P+ PG +GP G GPA P P GP GP Sbjct: 306 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 365 Query: 90 ALPAVRLSLVRLGEPDSAG-------AGEP--PATPAGLGSGGD 124 P + G + G GEP P +P G+ G+ Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409 Score = 37.7 bits (86), Expect = 0.035 Identities = 35/123 (28%), Positives = 38/123 (30%), Gaps = 13/123 (10%) Query: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60 M G G GP A G +GF G SGP + P P PP Sbjct: 203 MGPMGPRGPPGPAGAPGP-----------QGFQGNPGEPGEPGVSGPMGPRGP--PGPPG 249 Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 P A PG AG P P G P P + G P GA P G Sbjct: 250 KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309 Query: 121 SGG 123 G Sbjct: 310 ESG 312 Score = 37.7 bits (86), Expect = 0.035 Identities = 39/128 (30%), Positives = 42/128 (32%), Gaps = 31/128 (24%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 G+ G GP G+ R R G P A R PP P P G Sbjct: 318 GSPGPMGPRGLPGE--------RGRTG-----PAGAAGARGNDGQPGPAGPPGPVGPAGG 364 Query: 65 PASASGPGA---AGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT--- 115 P PGA AGP + P GP P P G P AGA P T Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP---------GSPGPAGASGNPGTDGI 415 Query: 116 PAGLGSGG 123 P GS G Sbjct: 416 PGAKGSAG 423 Score = 37.7 bits (86), Expect = 0.035 Identities = 42/127 (33%), Positives = 48/127 (37%), Gaps = 22/127 (17%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPP-----QPP 59 G G +GP A GD R G L G R G A Q V P + Sbjct: 534 GPSGLAGPKGANGDPG--------RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 585 Query: 60 QP-PPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111 +P PPGP A G PG G P AG P P +R + GE +AG Sbjct: 586 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP-P 644 Query: 112 PPATPAG 118 PA PAG Sbjct: 645 GPAGPAG 651 Score = 37.7 bits (86), Expect = 0.035 Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 4/109 (3%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PG T PA R G PG P + G G PG PG+P G Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG-- 1080 Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSR 572 T +R + GA+ G +RG G G G+K P R Sbjct: 1081 PTGKQGDRGEAGAQGPMGPSGPAG--ARGIQGPQGPRGDKGEAGEPGER 1127 Score = 37.4 bits (85), Expect = 0.046 Identities = 56/200 (28%), Positives = 67/200 (33%), Gaps = 28/200 (14%) Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGG----APLSPLPKAGSITYRFGSAGQDTQFC 441 AA AG G+R G+ E+ PE A G GG P+ P AG+ G G+ Sbjct: 757 AAGIAGPKGDR-GDVGEKGPEGA-PGKDGGRGLTGPIGPPGPAGAN----GEKGE----- 805 Query: 442 LWDLTEDVLYPHPP-LARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA 500 V P P A R PG G T P + G PG P + Sbjct: 806 -------VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK- 857 Query: 501 GGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSG 560 G AG PG G P G T + RGA+ G R G GS Sbjct: 858 --GDAGAPGPQGPSGAPGPQG--PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN 913 Query: 561 GEKPSGPVPRSRLDPAKVLG 580 P P P + P G Sbjct: 914 PGPPGPPGPSGKDGPKGARG 933 Score = 37.0 bits (84), Expect = 0.059 Identities = 34/114 (29%), Positives = 41/114 (35%), Gaps = 20/114 (17%) Query: 12 PGAAMGDCAEI-KSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASG 70 P G+C I + T G PG ++ P + V P+ P P GPA G Sbjct: 78 PEIPFGECCPICPTDLATASG----QPGP-KGQKGEPGDIKDIVGPKGPPGPQGPAGEQG 132 Query: 71 P----GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 P G G +P P G P P G P G PP P GLG Sbjct: 133 PRGDRGDKGEKGAPGPRGRDGEPGTP---------GNPGPPGPPGPPG-PPGLG 176 Score = 36.6 bits (83), Expect = 0.078 Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 15/55 (27%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PGTPG+ PA +S G PG + P G AG PG+A PG P Sbjct: 395 PGTPGSPGPAGAS---GNPGTDGI------------PGAKGSAGAPGIAGAPGFP 434 Score = 36.2 bits (82), Expect = 0.10 Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 23/112 (20%) Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519 R LPGTPGT P +S G PG P +P G+ G G+A G Sbjct: 719 RGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP-----GERGAAGIAGPKGDRGD 769 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK----PSGP 567 +G E+ GA + G I G G +G+ GEK P GP Sbjct: 770 VG--------EKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGP 811 Score = 35.8 bits (81), Expect = 0.13 Identities = 49/161 (30%), Positives = 56/161 (34%), Gaps = 50/161 (31%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP 61 A G +G GP G GF PG GA +GP A+ P Q P+ Sbjct: 343 ARGNDGQPGPAGPPGPVGPAGGP-----GF----PGAPGAKGEAGPTGARGPEGAQGPRG 393 Query: 62 PPG------PASASG-------PGAAGPASSPPPAG----------PGP----GPALPAV 94 PG PA ASG PGA G A +P AG PGP GP P Sbjct: 394 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 453 Query: 95 RLSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125 + + GEP AG P P G G R Sbjct: 454 QTGEPGIAGFKGEQGPKGEPGPAG---PQGAPGPAGEEGKR 491 Score = 35.8 bits (81), Expect = 0.13 Identities = 58/193 (30%), Positives = 62/193 (32%), Gaps = 44/193 (22%) Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445 +A A GA GER E P AG GA P K G AGQ Sbjct: 814 SAGARGAPGERG---ETGPPGPAGFAGPPGADGQPGAKGEQ-----GEAGQKG------- 858 Query: 446 TEDVLYPHPPLARTRTLP-GTPGTTPPAASSSRGGEPGPGPLPRSLSR-----SNSLPHP 499 D P P P G G T P + G PG P + R SN P P Sbjct: 859 --DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916 Query: 500 AG----GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSG 555 G GK G G + G P GR LQ EK G G Sbjct: 917 PGPPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEK-------------GEPG 960 Query: 556 GSG-SGGEKPSGP 567 G SG E P GP Sbjct: 961 DDGPSGAEGPPGP 973 Score = 35.8 bits (81), Expect = 0.13 Identities = 46/176 (26%), Positives = 60/176 (34%), Gaps = 16/176 (9%) Query: 357 EGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGA 416 EG A G + V D T A A A G G + G A G Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQG- 1095 Query: 417 PLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSS 476 P+ P AG+ + + + + E L H + LPG PG + +S Sbjct: 1096 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1155 Query: 477 RGGEPGP----GPL-PRSLSRSNSLPHPAGG----------GKAGGPGVAAEPGTP 517 G GP GP+ P +N +P P G G AG PG PG P Sbjct: 1156 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1211 Score = 35.4 bits (80), Expect = 0.17 Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 15/77 (19%) Query: 460 RTLPGTPGTTPPA-ASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAG--------GP 508 R LPG G T PA A+ +RG G+PGP P + + P G G GP Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385 Query: 509 ----GVAAEPGTPFSIG 521 G EPGTP S G Sbjct: 386 EGAQGPRGEPGTPGSPG 402 Score = 35.4 bits (80), Expect = 0.17 Identities = 21/68 (30%), Positives = 25/68 (36%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PG P+ G PGP P RS G G PG PG + F Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1223 Query: 524 ATLTLQER 531 A L +E+ Sbjct: 1224 AGLGPREK 1231 Score = 35.0 bits (79), Expect = 0.23 Identities = 39/134 (29%), Positives = 43/134 (32%), Gaps = 15/134 (11%) Query: 383 AEEAATAAGADGERSGEEEEEEPEAAGT-GSAGGAPLSPLPKAGSITYRFGSAGQDTQFC 441 A A AG G R E + GT GS G A S P I GSAG Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG--- 426 Query: 442 LWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG 501 + P R PG G T P + GEPG + P Sbjct: 427 --------IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG---IAGFKGEQGPKGEPGP 475 Query: 502 GGKAGGPGVAAEPG 515 G G PG A E G Sbjct: 476 AGPQGAPGPAGEEG 489 Score = 33.9 bits (76), Expect = 0.50 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 5/67 (7%) Query: 453 HPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG----GKAGGP 508 +P L + G PG + S G PGP PR L PAG G G P Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-PRGLPGERGRTGPAGAAGARGNDGQP 350 Query: 509 GVAAEPG 515 G A PG Sbjct: 351 GPAGPPG 357 Score = 33.9 bits (76), Expect = 0.50 Identities = 37/138 (26%), Positives = 45/138 (32%), Gaps = 23/138 (16%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD----GAARRSGPASAQ-------TP 53 G G GP A G+ + + + LPG GAA GPA P Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659 Query: 54 VP------PQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSA 107 P P PP PP G G A +P GP P R G P + Sbjct: 660 GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER------GSPGAQ 713 Query: 108 GAGEPPATPAGLGSGGDR 125 G P P G+ G + Sbjct: 714 GLQGPRGLPGTPGTDGPK 731 Score = 33.1 bits (74), Expect = 0.86 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 6/74 (8%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRGGEPG----PGPLPRSLSRSNS--LPHPAGGGKAGG 507 P L R L G PG P G PG PGP +R + P G G Sbjct: 554 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 613 Query: 508 PGVAAEPGTPFSIG 521 PG A E G P + G Sbjct: 614 PGKAGEKGLPGAPG 627 Score = 32.7 bits (73), Expect = 1.1 Identities = 32/124 (25%), Positives = 43/124 (34%), Gaps = 14/124 (11%) Query: 6 AEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP--- 62 A G GP G+ +IK ++ G GPA Q P + + Sbjct: 96 ASGQPGPKGQKGEPGDIKD----------IVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145 Query: 63 PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGS 121 PGP G PG G P P GP P L + + G + AG + +G Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP 205 Query: 122 GGDR 125 G R Sbjct: 206 MGPR 209 Score = 32.7 bits (73), Expect = 1.1 Identities = 30/97 (30%), Positives = 32/97 (32%), Gaps = 13/97 (13%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPG----PASASGPGAAGPASSPPPA---GPGPGPALP 92 G GP A P P Q PPG P G AGP GP P Sbjct: 723 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 782 Query: 93 AVRLSLVRLGEPDSAGA-GE-----PPATPAGLGSGG 123 R +G P AGA GE PP G+ G Sbjct: 783 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 819 Score = 32.0 bits (71), Expect = 1.9 Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 24/82 (29%) Query: 464 GTPGTTPPAASSSRGGEPG----------PGP-----------LPRSLSRSN--SLPHPA 500 G PG PA GEPG PGP LP LP P+ Sbjct: 942 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001 Query: 501 GG-GKAGGPGVAAEPGTPFSIG 521 G GK G PG + + G P +G Sbjct: 1002 GEPGKQGAPGASGDRGPPGPVG 1023 Score = 31.6 bits (70), Expect = 2.5 Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 14/139 (10%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP----LPKAGSITYRFGSAGQDTQFCLWDLT 446 G G + E AG A G P P LP A +T R G AG + Sbjct: 522 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 581 Query: 447 EDVLYPHPPLAR-TRTLPGTPGTTPPAASSSRGGEPG----PGP-----LPRSLSRSNSL 496 + P PP + R PG G P ++ G+ G PG LP + + Sbjct: 582 GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 641 Query: 497 PHPAGGGKAGGPGVAAEPG 515 P G AG G PG Sbjct: 642 GPPGPAGPAGERGEQGAPG 660 Score = 31.6 bits (70), Expect = 2.5 Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 10/68 (14%) Query: 57 QPPQPPPGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT 115 Q P+ PG GP GA+GPA P GP +P GE +AG P Sbjct: 716 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP---------GERGAAGIAGPKGD 766 Query: 116 PAGLGSGG 123 +G G Sbjct: 767 RGDVGEKG 774 Score = 31.2 bits (69), Expect = 3.3 Identities = 54/216 (25%), Positives = 64/216 (29%), Gaps = 43/216 (19%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVL 450 GA G R + E P G G P P G + + + + Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203 Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPG-------------PGPLPRSLSRSNSLP 497 P P R PG G P GEPG PGP P Sbjct: 204 GPMGP----RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-PGKPGDDGEAG 258 Query: 498 HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-----SRG 552 P G+ G PG G P + G K H+ Y L + G Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPG------------LPGVKGHRGYPGLDGAKGEAGAPG 306 Query: 553 GSGGSGSGGEK----PSGP--VP--RSRLDPAKVLG 580 G SGS GE P GP +P R R PA G Sbjct: 307 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG 342 Score = 30.4 bits (67), Expect = 5.6 Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP-GAAGPASSPPPAGP-GP 87 GA GP + P P Q G A A GP G +GPA + GP GP Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114 Score = 30.0 bits (66), Expect = 7.3 Identities = 41/136 (30%), Positives = 51/136 (37%), Gaps = 14/136 (10%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP--LPKAGSITYRFGSAGQDTQFCLWDLTED 448 GA GE + E + G + G P+ P LP T G+AG D Sbjct: 297 GAKGEAGAPGVKGESGSPGENGSPG-PMGPRGLPGERGRTGPAGAAGARGN----DGQPG 351 Query: 449 VLYPHPPL--ARTRTLPGTPGTTPPAA-SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKA 505 P P+ A PG PG A + +RG E GP R + P PAG + Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP--RGEPGTPGSPGPAGA--S 407 Query: 506 GGPGVAAEPGTPFSIG 521 G PG PG S G Sbjct: 408 GNPGTDGIPGAKGSAG 423 Score = 30.0 bits (66), Expect = 7.3 Identities = 41/149 (27%), Positives = 49/149 (32%), Gaps = 31/149 (20%) Query: 5 GAEGGSGPGAAMGDCAEIK-SQFRTREGFYKLLPGD-------GAARRSGPASAQTPVPP 56 G +G +GP G E + F+ +G K PG G A G A+ Sbjct: 441 GPQGATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 499 Query: 57 QPPQPPPGPASASG-------PGAAGPASSPPPAGPG-----------PG----PALPAV 94 P PPG A G G AGP +P GP PG P LP Sbjct: 500 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 559 Query: 95 RLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 R R G+ G P P G G Sbjct: 560 RGLTGRPGDAGPQGKVGPSGAPGEDGRPG 588 Score = 29.6 bits (65), Expect = 9.5 Identities = 34/98 (34%), Positives = 37/98 (37%), Gaps = 23/98 (23%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ----------TP 53 G G GP G E REG PG DG R G A + P Sbjct: 1017 GPPGPVGPPGLTGPAGE-----PGREGS----PGADGPPGRDGAAGVKGDRGETGAVGAP 1067 Query: 54 VPPQPPQPPPGPASASG-PGAAGPASSPPPAGPGPGPA 90 P PP PGPA +G G G A + P GP GPA Sbjct: 1068 GAPGPP-GSPGPAGPTGKQGDRGEAGAQGPMGPS-GPA 1103 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 48.5 bits (114), Expect = 2e-05 Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 23/132 (17%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQ-FRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61 A G +G GP G+ E + + GF L G SG A P P P+ Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1095 Query: 62 PPGPASASG-------------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAG 108 PPGP SG PG G + PAGP P P G P G Sbjct: 1096 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP---------GPPGPPG 1146 Query: 109 AGEPPATPAGLG 120 G + AGLG Sbjct: 1147 PGIDMSAFAGLG 1158 Score = 45.8 bits (107), Expect = 1e-04 Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 8/86 (9%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLV 99 G A + G A A P P P GP +GP A A PP A PG A Sbjct: 783 GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA--------G 834 Query: 100 RLGEPDSAGAGEPPATPAGLGSGGDR 125 R+G P S G PP P G G + Sbjct: 835 RVGPPGSNGNPGPPGPPGPSGKDGPK 860 Score = 42.0 bits (97), Expect = 0.002 Identities = 44/141 (31%), Positives = 49/141 (34%), Gaps = 24/141 (17%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ--TPVPPQP-PQ 60 G G GP A G E + PG DG G A A P P P+ Sbjct: 309 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 368 Query: 61 PPPGPASASGP----------------GAAGPASSPPPAGP--GPGPALPAVRLSLVRLG 102 PPGP A+GP G GP P PAGP PGPA + G Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--ARG 426 Query: 103 EPDSAGAGEPPATPAGLGSGG 123 EP G PP G+ G Sbjct: 427 EPGGVGPIGPPGERGAPGNRG 447 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 7/80 (8%) Query: 51 QTPVPPQPPQPPPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGE 103 Q P+ P P+ PPGPA A G PG G P GP P P G+ Sbjct: 131 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190 Query: 104 PDSAGAGEPPATPAGLGSGG 123 P AG PP G G Sbjct: 191 PGKAGERGPPGPQGARGFPG 210 Score = 41.2 bits (95), Expect = 0.003 Identities = 32/123 (26%), Positives = 43/123 (34%), Gaps = 2/123 (1%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGA--ARRSGPASAQTPVPPQPPQPP 62 GAEG GP G + + E + LPG ++ P ++ PP P PP Sbjct: 897 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 956 Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122 A PG G + P G + R +G P + G P G Sbjct: 957 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016 Query: 123 GDR 125 GDR Sbjct: 1017 GDR 1019 Score = 40.8 bits (94), Expect = 0.004 Identities = 43/120 (35%), Positives = 45/120 (37%), Gaps = 33/120 (27%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 GA G GP A G PG A R P S P PP PP G Sbjct: 816 GARGAQGPPGATG------------------FPG-AAGRVGPPGSNGNPGPPGPP----G 852 Query: 65 PASASGP-GAAGPASSPPPAG-PG-PGPALPAVRLSLVRLGEP--DSAGAGEPPATPAGL 119 P+ GP GA G + P AG PG GPA P GEP D E P P GL Sbjct: 853 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-----GEKGEPGDDGPSGAEGPPGPQGL 907 Score = 40.4 bits (93), Expect = 0.005 Identities = 38/113 (33%), Positives = 43/113 (38%), Gaps = 24/113 (21%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG----GGKAGGPGVAAEPGTPFS 519 G PG PA G PGP S LP P G GGK G GV E G P Sbjct: 573 GPPGPAGPAGERGEQGAPGP-------SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLG-NISRGGSGGSGSGGEK----PSGP 567 +G R +RG E + G RG G G+ G K P+GP Sbjct: 626 VG--------PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670 Score = 38.5 bits (88), Expect = 0.020 Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 20/130 (15%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP-- 61 GA G +GP GD E + EG PG DG +GP P + Sbjct: 687 GAAGIAGPKGDRGDVGE-----KGPEG----APGKDGGRGLTGPIGPPGPAGANGEKGEV 737 Query: 62 -PPGPASASG----PGAAGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113 PPGPA ++G PG G P P AGP P + G+ AGA P Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797 Query: 114 ATPAGLGSGG 123 G G Sbjct: 798 GPSGAPGPQG 807 Score = 38.1 bits (87), Expect = 0.027 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 20/119 (16%) Query: 463 PGTPGTTPPAASSSRGGEPGP-GPL-PRSLSRSNSLPHPAGG----------GKAGGPGV 510 PG PG A + GE GP GP R + LP G G+AG PGV Sbjct: 179 PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 238 Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-SRGGSGGSGSGGEKPSGPV 568 E G+P G + RG E R G +RG G G G P GPV Sbjct: 239 KGESGSPGENGSPGPM-----GPRGLPGERGRTGPAGAAGARGNDGQPGPAG--PPGPV 290 Score = 38.1 bits (87), Expect = 0.027 Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 19/104 (18%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP----------GAAGPASSPPPAGPGPGP 89 G SG P P+ PG +GP G GPA P P GP GP Sbjct: 237 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 296 Query: 90 ALPAVRLSLVRLGEPDSAG-------AGEP--PATPAGLGSGGD 124 P + G + G GEP P +P G+ G+ Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340 Score = 37.7 bits (86), Expect = 0.035 Identities = 35/123 (28%), Positives = 38/123 (30%), Gaps = 13/123 (10%) Query: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60 M G G GP A G +GF G SGP + P P PP Sbjct: 134 MGPMGPRGPPGPAGAPGP-----------QGFQGNPGEPGEPGVSGPMGPRGP--PGPPG 180 Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120 P A PG AG P P G P P + G P GA P G Sbjct: 181 KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240 Query: 121 SGG 123 G Sbjct: 241 ESG 243 Score = 37.7 bits (86), Expect = 0.035 Identities = 39/128 (30%), Positives = 42/128 (32%), Gaps = 31/128 (24%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 G+ G GP G+ R R G P A R PP P P G Sbjct: 249 GSPGPMGPRGLPGE--------RGRTG-----PAGAAGARGNDGQPGPAGPPGPVGPAGG 295 Query: 65 PASASGPGA---AGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT--- 115 P PGA AGP + P GP P P G P AGA P T Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP---------GSPGPAGASGNPGTDGI 346 Query: 116 PAGLGSGG 123 P GS G Sbjct: 347 PGAKGSAG 354 Score = 37.7 bits (86), Expect = 0.035 Identities = 42/127 (33%), Positives = 48/127 (37%), Gaps = 22/127 (17%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPP-----QPP 59 G G +GP A GD R G L G R G A Q V P + Sbjct: 465 GPSGLAGPKGANGDPG--------RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 516 Query: 60 QP-PPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111 +P PPGP A G PG G P AG P P +R + GE +AG Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP-P 575 Query: 112 PPATPAG 118 PA PAG Sbjct: 576 GPAGPAG 582 Score = 37.7 bits (86), Expect = 0.035 Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 4/109 (3%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PG T PA R G PG P + G G PG PG+P G Sbjct: 954 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG-- 1011 Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSR 572 T +R + GA+ G +RG G G G+K P R Sbjct: 1012 PTGKQGDRGEAGAQGPMGPSGPAG--ARGIQGPQGPRGDKGEAGEPGER 1058 Score = 37.4 bits (85), Expect = 0.046 Identities = 56/200 (28%), Positives = 67/200 (33%), Gaps = 28/200 (14%) Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGG----APLSPLPKAGSITYRFGSAGQDTQFC 441 AA AG G+R G+ E+ PE A G GG P+ P AG+ G G+ Sbjct: 688 AAGIAGPKGDR-GDVGEKGPEGA-PGKDGGRGLTGPIGPPGPAGAN----GEKGE----- 736 Query: 442 LWDLTEDVLYPHPP-LARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA 500 V P P A R PG G T P + G PG P + Sbjct: 737 -------VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK- 788 Query: 501 GGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSG 560 G AG PG G P G T + RGA+ G R G GS Sbjct: 789 --GDAGAPGPQGPSGAPGPQG--PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN 844 Query: 561 GEKPSGPVPRSRLDPAKVLG 580 P P P + P G Sbjct: 845 PGPPGPPGPSGKDGPKGARG 864 Score = 36.6 bits (83), Expect = 0.078 Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 15/55 (27%) Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517 PGTPG+ PA +S G PG + P G AG PG+A PG P Sbjct: 326 PGTPGSPGPAGAS---GNPGTDGI------------PGAKGSAGAPGIAGAPGFP 365 Score = 36.2 bits (82), Expect = 0.10 Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 14/82 (17%) Query: 43 RRSGPASAQTPVPPQPPQPPPGPASASGP----GAAGPASSPPPAGPGPGPALPAVRLSL 98 ++ P + V P+ P P GPA GP G G +P P G P P Sbjct: 36 QKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP------ 89 Query: 99 VRLGEPDSAGAGEPPATPAGLG 120 G P G PP P GLG Sbjct: 90 ---GNPGPPGPPGPPG-PPGLG 107 Score = 36.2 bits (82), Expect = 0.10 Identities = 38/142 (26%), Positives = 42/142 (29%), Gaps = 36/142 (25%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64 G G GP GD E K PG R P + P PP PP PPG Sbjct: 57 GPAGEQGPRGDRGDKGE------------KGAPGP-RGRDGEPGTPGNPGPPGPPG-PPG 102 Query: 65 PASASG----------------------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLG 102 P G G GP P GP P + + G Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162 Query: 103 EPDSAGAGEPPATPAGLGSGGD 124 EP +G P P G GD Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGD 184 Score = 36.2 bits (82), Expect = 0.10 Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 23/112 (20%) Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519 R LPGTPGT P +S G PG P +P G+ G G+A G Sbjct: 650 RGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP-----GERGAAGIAGPKGDRGD 700 Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK----PSGP 567 +G E+ GA + G I G G +G+ GEK P GP Sbjct: 701 VG--------EKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGP 742 Score = 35.8 bits (81), Expect = 0.13 Identities = 49/161 (30%), Positives = 56/161 (34%), Gaps = 50/161 (31%) Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP 61 A G +G GP G GF PG GA +GP A+ P Q P+ Sbjct: 274 ARGNDGQPGPAGPPGPVGPAGGP-----GF----PGAPGAKGEAGPTGARGPEGAQGPRG 324 Query: 62 PPG------PASASG-------PGAAGPASSPPPAG----------PGP----GPALPAV 94 PG PA ASG PGA G A +P AG PGP GP P Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 384 Query: 95 RLSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125 + + GEP AG P P G G R Sbjct: 385 QTGEPGIAGFKGEQGPKGEPGPAG---PQGAPGPAGEEGKR 422 Score = 35.8 bits (81), Expect = 0.13 Identities = 58/193 (30%), Positives = 62/193 (32%), Gaps = 44/193 (22%) Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445 +A A GA GER E P AG GA P K G AGQ Sbjct: 745 SAGARGAPGERG---ETGPPGPAGFAGPPGADGQPGAKGEQ-----GEAGQKG------- 789 Query: 446 TEDVLYPHPPLARTRTLP-GTPGTTPPAASSSRGGEPGPGPLPRSLSR-----SNSLPHP 499 D P P P G G T P + G PG P + R SN P P Sbjct: 790 --DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847 Query: 500 AG----GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSG 555 G GK G G + G P GR LQ EK G G Sbjct: 848 PGPPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEK-------------GEPG 891 Query: 556 GSG-SGGEKPSGP 567 G SG E P GP Sbjct: 892 DDGPSGAEGPPGP 904 Score = 35.8 bits (81), Expect = 0.13 Identities = 46/176 (26%), Positives = 60/176 (34%), Gaps = 16/176 (9%) Query: 357 EGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGA 416 EG A G + V D T A A A G G + G A G Sbjct: 968 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQG- 1026 Query: 417 PLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSS 476 P+ P AG+ + + + + E L H + LPG PG + +S Sbjct: 1027 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1086 Query: 477 RGGEPGP----GPL-PRSLSRSNSLPHPAGG----------GKAGGPGVAAEPGTP 517 G GP GP+ P +N +P P G G AG PG PG P Sbjct: 1087 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1142 Score = 35.4 bits (80), Expect = 0.17 Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 15/77 (19%) Query: 460 RTLPGTPGTTPPA-ASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAG--------GP 508 R LPG G T PA A+ +RG G+PGP P + + P G G GP Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316 Query: 509 ----GVAAEPGTPFSIG 521 G EPGTP S G Sbjct: 317 EGAQGPRGEPGTPGSPG 333 Score = 35.4 bits (80), Expect = 0.17 Identities = 21/68 (30%), Positives = 25/68 (36%) Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523 G PG P+ G PGP P RS G G PG PG + F Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1154 Query: 524 ATLTLQER 531 A L +E+ Sbjct: 1155 AGLGPREK 1162 Score = 35.0 bits (79), Expect = 0.23 Identities = 39/134 (29%), Positives = 43/134 (32%), Gaps = 15/134 (11%) Query: 383 AEEAATAAGADGERSGEEEEEEPEAAGT-GSAGGAPLSPLPKAGSITYRFGSAGQDTQFC 441 A A AG G R E + GT GS G A S P I GSAG Sbjct: 301 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG--- 357 Query: 442 LWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG 501 + P R PG G T P + GEPG + P Sbjct: 358 --------IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG---IAGFKGEQGPKGEPGP 406 Query: 502 GGKAGGPGVAAEPG 515 G G PG A E G Sbjct: 407 AGPQGAPGPAGEEG 420 Score = 33.9 bits (76), Expect = 0.50 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 5/67 (7%) Query: 453 HPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG----GKAGGP 508 +P L + G PG + S G PGP PR L PAG G G P Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-PRGLPGERGRTGPAGAAGARGNDGQP 281 Query: 509 GVAAEPG 515 G A PG Sbjct: 282 GPAGPPG 288 Score = 33.9 bits (76), Expect = 0.50 Identities = 37/138 (26%), Positives = 45/138 (32%), Gaps = 23/138 (16%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD----GAARRSGPASAQ-------TP 53 G G GP A G+ + + + LPG GAA GPA P Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 590 Query: 54 VP------PQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSA 107 P P PP PP G G A +P GP P R G P + Sbjct: 591 GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER------GSPGAQ 644 Query: 108 GAGEPPATPAGLGSGGDR 125 G P P G+ G + Sbjct: 645 GLQGPRGLPGTPGTDGPK 662 Score = 33.1 bits (74), Expect = 0.86 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 6/74 (8%) Query: 454 PPLARTRTLPGTPGTTPPAASSSRGGEPG----PGPLPRSLSRSNS--LPHPAGGGKAGG 507 P L R L G PG P G PG PGP +R + P G G Sbjct: 485 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 544 Query: 508 PGVAAEPGTPFSIG 521 PG A E G P + G Sbjct: 545 PGKAGEKGLPGAPG 558 Score = 32.7 bits (73), Expect = 1.1 Identities = 30/97 (30%), Positives = 32/97 (32%), Gaps = 13/97 (13%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPG----PASASGPGAAGPASSPPPA---GPGPGPALP 92 G GP A P P Q PPG P G AGP GP P Sbjct: 654 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 713 Query: 93 AVRLSLVRLGEPDSAGA-GE-----PPATPAGLGSGG 123 R +G P AGA GE PP G+ G Sbjct: 714 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 750 Score = 32.0 bits (71), Expect = 1.9 Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 24/82 (29%) Query: 464 GTPGTTPPAASSSRGGEPG----------PGP-----------LPRSLSRSN--SLPHPA 500 G PG PA GEPG PGP LP LP P+ Sbjct: 873 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932 Query: 501 GG-GKAGGPGVAAEPGTPFSIG 521 G GK G PG + + G P +G Sbjct: 933 GEPGKQGAPGASGDRGPPGPVG 954 Score = 31.6 bits (70), Expect = 2.5 Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 14/139 (10%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP----LPKAGSITYRFGSAGQDTQFCLWDLT 446 G G + E AG A G P P LP A +T R G AG + Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 512 Query: 447 EDVLYPHPPLAR-TRTLPGTPGTTPPAASSSRGGEPG----PGP-----LPRSLSRSNSL 496 + P PP + R PG G P ++ G+ G PG LP + + Sbjct: 513 GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 572 Query: 497 PHPAGGGKAGGPGVAAEPG 515 P G AG G PG Sbjct: 573 GPPGPAGPAGERGEQGAPG 591 Score = 31.6 bits (70), Expect = 2.5 Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 10/68 (14%) Query: 57 QPPQPPPGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT 115 Q P+ PG GP GA+GPA P GP +P GE +AG P Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP---------GERGAAGIAGPKGD 697 Query: 116 PAGLGSGG 123 +G G Sbjct: 698 RGDVGEKG 705 Score = 31.2 bits (69), Expect = 3.3 Identities = 54/216 (25%), Positives = 64/216 (29%), Gaps = 43/216 (19%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVL 450 GA G R + E P G G P P G + + + + Sbjct: 75 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 134 Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPG-------------PGPLPRSLSRSNSLP 497 P P R PG G P GEPG PGP P Sbjct: 135 GPMGP----RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-PGKPGDDGEAG 189 Query: 498 HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-----SRG 552 P G+ G PG G P + G K H+ Y L + G Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPG------------LPGVKGHRGYPGLDGAKGEAGAPG 237 Query: 553 GSGGSGSGGEK----PSGP--VP--RSRLDPAKVLG 580 G SGS GE P GP +P R R PA G Sbjct: 238 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG 273 Score = 30.8 bits (68), Expect = 4.3 Identities = 25/90 (27%), Positives = 31/90 (34%), Gaps = 10/90 (11%) Query: 46 GPASAQTPVPPQPPQPP---------PGPASASG-PGAAGPASSPPPAGPGPGPALPAVR 95 GP Q P Q P+ PGP G PG G P P GP P L Sbjct: 51 GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF 110 Query: 96 LSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125 + + G + AG + +G G R Sbjct: 111 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140 Score = 30.4 bits (67), Expect = 5.6 Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP-GAAGPASSPPPAGP-GP 87 GA GP + P P Q G A A GP G +GPA + GP GP Sbjct: 996 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045 Score = 30.0 bits (66), Expect = 7.3 Identities = 41/136 (30%), Positives = 51/136 (37%), Gaps = 14/136 (10%) Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP--LPKAGSITYRFGSAGQDTQFCLWDLTED 448 GA GE + E + G + G P+ P LP T G+AG D Sbjct: 228 GAKGEAGAPGVKGESGSPGENGSPG-PMGPRGLPGERGRTGPAGAAGARGN----DGQPG 282 Query: 449 VLYPHPPL--ARTRTLPGTPGTTPPAA-SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKA 505 P P+ A PG PG A + +RG E GP R + P PAG + Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP--RGEPGTPGSPGPAGA--S 338 Query: 506 GGPGVAAEPGTPFSIG 521 G PG PG S G Sbjct: 339 GNPGTDGIPGAKGSAG 354 Score = 30.0 bits (66), Expect = 7.3 Identities = 41/149 (27%), Positives = 49/149 (32%), Gaps = 31/149 (20%) Query: 5 GAEGGSGPGAAMGDCAEIK-SQFRTREGFYKLLPGD-------GAARRSGPASAQTPVPP 56 G +G +GP G E + F+ +G K PG G A G A+ Sbjct: 372 GPQGATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430 Query: 57 QPPQPPPGPASASG-------PGAAGPASSPPPAGPG-----------PG----PALPAV 94 P PPG A G G AGP +P GP PG P LP Sbjct: 431 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 490 Query: 95 RLSLVRLGEPDSAGAGEPPATPAGLGSGG 123 R R G+ G P P G G Sbjct: 491 RGLTGRPGDAGPQGKVGPSGAPGEDGRPG 519 Score = 29.6 bits (65), Expect = 9.5 Identities = 34/98 (34%), Positives = 37/98 (37%), Gaps = 23/98 (23%) Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ----------TP 53 G G GP G E REG PG DG R G A + P Sbjct: 948 GPPGPVGPPGLTGPAGE-----PGREGS----PGADGPPGRDGAAGVKGDRGETGAVGAP 998 Query: 54 VPPQPPQPPPGPASASG-PGAAGPASSPPPAGPGPGPA 90 P PP PGPA +G G G A + P GP GPA Sbjct: 999 GAPGPP-GSPGPAGPTGKQGDRGEAGAQGPMGPS-GPA 1034 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 48.5 bits (114), Expect = 2e-05 Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 5/63 (7%) Query: 46 GPASAQTPVPPQPPQPPPGPASASGPGAAGPA-----SSPPPAGPGPGPALPAVRLSLVR 100 GPA A +PP P PPP P ++GP P PPP P P P LPA L Sbjct: 322 GPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLAS 381 Query: 101 LGE 103 + E Sbjct: 382 MSE 384 Score = 43.1 bits (100), Expect = 8e-04 Identities = 26/70 (37%), Positives = 30/70 (42%), Gaps = 21/70 (30%) Query: 38 GDGAARRSGPASAQTPV--------------PPQPPQPPPGPASASGPGAAGPASSPPPA 83 GD +A G +A P PP PP PPGPA AS + PPP Sbjct: 282 GDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS-------VALPPPP 334 Query: 84 GPGPGPALPA 93 GP P P LP+ Sbjct: 335 GPPPPPPLPS 344 Score = 33.5 bits (75), Expect = 0.66 Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 18/84 (21%) Query: 45 SGPASAQTP---VPPQPPQPPPGPASASGPGAA--------GPASSPPPAGPGPGPALPA 93 + PAS +TP V PG +AS P GP + PPP PGPA + Sbjct: 268 AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS 327 Query: 94 VRLSLVRLGEPDSAGAGEPPATPA 117 V L P G PP P+ Sbjct: 328 VAL-------PPPPGPPPPPPLPS 344 Score = 32.0 bits (71), Expect = 1.9 Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 1/75 (1%) Query: 36 LPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVR 95 LP G P VPP PP PP P ASG A + P G A+ + Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPL-TGLAAAIAGAK 400 Query: 96 LSLVRLGEPDSAGAG 110 L V E S +G Sbjct: 401 LRKVSRMEDTSFPSG 415 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.135 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,002,893 Number of Sequences: 37866 Number of extensions: 2542840 Number of successful extensions: 55236 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1052 Number of HSP's successfully gapped in prelim test: 1611 Number of HSP's that attempted gapping in prelim test: 20406 Number of HSP's gapped (non-prelim): 22035 length of query: 674 length of database: 18,247,518 effective HSP length: 109 effective length of query: 565 effective length of database: 14,120,124 effective search space: 7977870060 effective search space used: 7977870060 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.