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Search of human proteins with 62945417
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62945417 dystrophia myotonica-containing WD repeat motif
protein [Homo sapiens]
(674 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62945417 dystrophia myotonica-containing WD repeat motif prot... 1394 0.0
gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens] 636 0.0
gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens] 636 0.0
gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens] 517 e-146
gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens] 501 e-142
gi|110832843 TBP-associated factor 4 [Homo sapiens] 55 2e-07
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 55 2e-07
gi|13376840 WD repeat domain 61 [Homo sapiens] 54 6e-07
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 52 1e-06
gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 52 2e-06
gi|113865883 WD repeat domain 38 [Homo sapiens] 52 2e-06
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 51 3e-06
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 51 3e-06
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 51 4e-06
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 50 5e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 50 7e-06
gi|39812378 RAN binding protein 9 [Homo sapiens] 50 7e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 50 7e-06
gi|134142824 forkhead box D2 [Homo sapiens] 50 9e-06
gi|7706501 WW domain binding protein 11 [Homo sapiens] 50 9e-06
gi|26665869 WD repeat domain 51B [Homo sapiens] 50 9e-06
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 49 1e-05
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 49 2e-05
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 49 2e-05
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 49 2e-05
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 49 2e-05
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 49 2e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 49 2e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 49 2e-05
gi|56549694 enabled homolog isoform a [Homo sapiens] 49 2e-05
>gi|62945417 dystrophia myotonica-containing WD repeat motif protein
[Homo sapiens]
Length = 674
Score = 1394 bits (3608), Expect = 0.0
Identities = 674/674 (100%), Positives = 674/674 (100%)
Query: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60
MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ
Sbjct: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60
Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG
Sbjct: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
Query: 121 SGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETI 180
SGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETI
Sbjct: 121 SGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETI 180
Query: 181 SLLVGFSAGQVQYLDLIKKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYL 240
SLLVGFSAGQVQYLDLIKKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYL
Sbjct: 181 SLLVGFSAGQVQYLDLIKKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYL 240
Query: 241 YNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLA 300
YNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLA
Sbjct: 241 YNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLA 300
Query: 301 CVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRV 360
CVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRV
Sbjct: 301 CVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRV 360
Query: 361 VARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSP 420
VARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSP
Sbjct: 361 VARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSP 420
Query: 421 LPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGE 480
LPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGE
Sbjct: 421 LPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGE 480
Query: 481 PGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEH 540
PGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEH
Sbjct: 481 PGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEH 540
Query: 541 KRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKK 600
KRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKK
Sbjct: 541 KRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKK 600
Query: 601 IAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQTGEGSWPRSPSKSVVEG 660
IAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQTGEGSWPRSPSKSVVEG
Sbjct: 601 IAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQTGEGSWPRSPSKSVVEG 660
Query: 661 ISSQPGNSPSGTVV 674
ISSQPGNSPSGTVV
Sbjct: 661 ISSQPGNSPSGTVV 674
>gi|31317274 WD repeat domain 20 isoform 1 [Homo sapiens]
Length = 581
Score = 636 bits (1641), Expect = 0.0
Identities = 341/621 (54%), Positives = 405/621 (65%), Gaps = 77/621 (12%)
Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80
EIK+QF TREG YKLLP +R P P + S P
Sbjct: 12 EIKTQFTTREGLYKLLPHSEYSR---------------PNRVPFNSQGSNP--------- 47
Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGC 140
VR+S V L D +G GDR+CFN+GRELYFY
Sbjct: 48 -------------VRVSFVNLN--DQSG-------------NGDRLCFNVGRELYFY--- 76
Query: 141 CRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLIKKD 200
+G +++ DL+KPIDKRIYKGTQPTCHDFN TA E++SLLVGFSAGQVQ +D IKK+
Sbjct: 77 IYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKE 136
Query: 201 TSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQG 260
TSKLFNEERLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQG
Sbjct: 137 TSKLFNEERLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQG 196
Query: 261 EGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRG 320
E F+V+ KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G
Sbjct: 197 ESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHG 256
Query: 321 LMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYT 380
MKSYFGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYT
Sbjct: 257 TMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYT 316
Query: 381 TRAEEAATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGS 433
T EE G E SG +E+ + A T S S + S+TYRFGS
Sbjct: 317 TSVEE-----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGS 371
Query: 434 AGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSR 492
GQDTQ CLWDLTED+L+PH PL+R RT T P A S+ PG +P L R
Sbjct: 372 VGQDTQLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPR 431
Query: 493 SNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRG 552
SNSLPH A AG + + +FATL+L +R++R EK+HKR HS+G+IS
Sbjct: 432 SNSLPHSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS-- 488
Query: 553 GSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFL 612
S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FL
Sbjct: 489 ------SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFL 542
Query: 613 EDCIITACQEGLICTWARPGK 633
EDCI+TACQEG ICTW RPGK
Sbjct: 543 EDCIVTACQEGFICTWGRPGK 563
>gi|31317280 WD repeat domain 20 isoform 2 [Homo sapiens]
Length = 569
Score = 636 bits (1641), Expect = 0.0
Identities = 341/621 (54%), Positives = 405/621 (65%), Gaps = 77/621 (12%)
Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80
EIK+QF TREG YKLLP +R P P + S P
Sbjct: 12 EIKTQFTTREGLYKLLPHSEYSR---------------PNRVPFNSQGSNP--------- 47
Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGC 140
VR+S V L D +G GDR+CFN+GRELYFY
Sbjct: 48 -------------VRVSFVNLN--DQSG-------------NGDRLCFNVGRELYFY--- 76
Query: 141 CRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLIKKD 200
+G +++ DL+KPIDKRIYKGTQPTCHDFN TA E++SLLVGFSAGQVQ +D IKK+
Sbjct: 77 IYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKE 136
Query: 201 TSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQG 260
TSKLFNEERLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQG
Sbjct: 137 TSKLFNEERLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQG 196
Query: 261 EGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRG 320
E F+V+ KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G
Sbjct: 197 ESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHG 256
Query: 321 LMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYT 380
MKSYFGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYT
Sbjct: 257 TMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYT 316
Query: 381 TRAEEAATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGS 433
T EE G E SG +E+ + A T S S + S+TYRFGS
Sbjct: 317 TSVEE-----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGS 371
Query: 434 AGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSR 492
GQDTQ CLWDLTED+L+PH PL+R RT T P A S+ PG +P L R
Sbjct: 372 VGQDTQLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPR 431
Query: 493 SNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRG 552
SNSLPH A AG + + +FATL+L +R++R EK+HKR HS+G+IS
Sbjct: 432 SNSLPHSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS-- 488
Query: 553 GSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFL 612
S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FL
Sbjct: 489 ------SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFL 542
Query: 613 EDCIITACQEGLICTWARPGK 633
EDCI+TACQEG ICTW RPGK
Sbjct: 543 EDCIVTACQEGFICTWGRPGK 563
>gi|31317278 WD repeat domain 20 isoform 3 [Homo sapiens]
Length = 508
Score = 517 bits (1331), Expect = e-146
Identities = 296/621 (47%), Positives = 353/621 (56%), Gaps = 138/621 (22%)
Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80
EIK+QF TREG YKLLP +R P P + S P
Sbjct: 12 EIKTQFTTREGLYKLLPHSEYSR---------------PNRVPFNSQGSNP--------- 47
Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGC 140
VR+S V L D +G GDR+CFN+GRELYFY
Sbjct: 48 -------------VRVSFVNLN--DQSG-------------NGDRLCFNVGRELYFY--- 76
Query: 141 CRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLIKKD 200
IYKG +
Sbjct: 77 ------------------IYKGVR------------------------------------ 82
Query: 201 TSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQG 260
+RLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQG
Sbjct: 83 -------KRLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQG 135
Query: 261 EGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRG 320
E F+V+ KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G
Sbjct: 136 ESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHG 195
Query: 321 LMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYT 380
MKSYFGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYT
Sbjct: 196 TMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYT 255
Query: 381 TRAEEAATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGS 433
T EE G E SG +E+ + A T S S + S+TYRFGS
Sbjct: 256 TSVEE-----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGS 310
Query: 434 AGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSR 492
GQDTQ CLWDLTED+L+PH PL+R RT T P A S+ PG +P L R
Sbjct: 311 VGQDTQLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPR 370
Query: 493 SNSLPHPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRG 552
SNSLPH A AG + + +FATL+L +R++R EK+HKR HS+G+IS
Sbjct: 371 SNSLPHSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS-- 427
Query: 553 GSGGSGSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFL 612
S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FL
Sbjct: 428 ------SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFL 481
Query: 613 EDCIITACQEGLICTWARPGK 633
EDCI+TACQEG ICTW RPGK
Sbjct: 482 EDCIVTACQEGFICTWGRPGK 502
>gi|31317276 WD repeat domain 20 isoform 4 [Homo sapiens]
Length = 445
Score = 501 bits (1290), Expect = e-142
Identities = 254/436 (58%), Positives = 303/436 (69%), Gaps = 22/436 (5%)
Query: 206 NEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLLKQGEGFSV 265
+ ERLIDK++VT +KW+P SESLFL +H+SG++YLYNV H C + P Y LLKQGE F+V
Sbjct: 18 SHERLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGESFAV 77
Query: 266 YAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSY 325
+ KSK+ RNPL KW VGEG LNEFAFSPDG+ LACVSQDG LRVF+FDS+ L G MKSY
Sbjct: 78 HTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHGTMKSY 137
Query: 326 FGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEE 385
FGGLLCVCWSPDG+Y+VTGGEDDLVTVWSF + RV+ARGHGHKSWV+ VAFDPYTT EE
Sbjct: 138 FGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYTTSVEE 197
Query: 386 AATAAGADGERSGEEEEEE-------PEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDT 438
G E SG +E+ + A T S S + S+TYRFGS GQDT
Sbjct: 198 -----GDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGSVGQDT 252
Query: 439 QFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-PLPRSLSRSNSLP 497
Q CLWDLTED+L+PH PL+R RT T P A S+ PG +P L RSNSLP
Sbjct: 253 QLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSNGNSVTTPGNSVPPPLPRSNSLP 312
Query: 498 HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGS 557
H A AG + + +FATL+L +R++R EK+HKR HS+G+IS
Sbjct: 313 HSA-VSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHIS------- 364
Query: 558 GSGGEKPSGPVPRSRLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFLEDCII 617
S V +++ DPAK LGT LCPR+ +VPLLEPL+CKKIA ERLTVL+FLEDCI+
Sbjct: 365 -SKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFLEDCIV 423
Query: 618 TACQEGLICTWARPGK 633
TACQEG ICTW RPGK
Sbjct: 424 TACQEGFICTWGRPGK 439
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 55.5 bits (132), Expect = 2e-07
Identities = 45/129 (34%), Positives = 53/129 (41%), Gaps = 18/129 (13%)
Query: 3 AGGAEGGSGPGA----AMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQP 58
AG A G+GP A A G E R R PG G +R GP S + P+ P
Sbjct: 68 AGAA--GAGPAAPAEGAPGAAPEPPPAGRAR-------PGGGGPQRPGPPSPRRPLVPAG 118
Query: 59 PQPP-----PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113
P PP P P ++G A PA++ AGP P PA PA L G G P
Sbjct: 119 PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178
Query: 114 ATPAGLGSG 122
G G G
Sbjct: 179 GPGPGPGPG 187
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/62 (43%), Positives = 30/62 (48%), Gaps = 5/62 (8%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA----AGPASSPPPA-GPGPGPAL 91
P +G+A P A V P P GPA +GP A AGP P P GPGPGP
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188
Query: 92 PA 93
PA
Sbjct: 189 PA 190
Score = 43.1 bits (100), Expect = 8e-04
Identities = 38/115 (33%), Positives = 44/115 (38%), Gaps = 15/115 (13%)
Query: 10 SGPGAAM---GDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPP----QPP 62
+GPGAA G A + S + G A +A V PP P
Sbjct: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPA 117
P PA+ S P A PA+ P A P P P PA L P AG P A PA
Sbjct: 250 PAPAAPSPPAAPAPAA--PAAAPPPPPPAPAT------LARPPGHPAGPPTAAPA 296
Score = 40.8 bits (94), Expect = 0.004
Identities = 42/154 (27%), Positives = 53/154 (34%), Gaps = 24/154 (15%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQP-----PPGPASASGPGAAGPASSPPPAGPGPGPAL 91
P GAA PA+ P P P P PP PA A+ G + PP A P P
Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA 301
Query: 92 PAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGCCRRGSQRSIDL 151
A SAGA PA AG +G V G PG +
Sbjct: 302 AA--------QNGGSAGAAPAPAPAAGGPAG---VSGQPG------PGAAAAAPAPGVKA 344
Query: 152 NKPIDKRIYKGTQPTCHDFNQFTAATETISLLVG 185
P KR+ + P A+ S+++G
Sbjct: 345 ESP--KRVVQAAPPAAQTLAASGPASTAASMVIG 376
Score = 40.0 bits (92), Expect = 0.007
Identities = 42/127 (33%), Positives = 48/127 (37%), Gaps = 29/127 (22%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAAR------RSGPASAQTPVP-PQ 57
G G GPG G A +T G LL AA +GPA A P+P P
Sbjct: 179 GPGPGPGPGKPAGPGAA-----QTLNGSAALLNSHHAAAPAVSLVNNGPA-ALLPLPKPA 232
Query: 58 PP----QPPP--GPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111
P Q PP G A+ P A P ++P PA P P P P A
Sbjct: 233 APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP----------PAPATLAR 282
Query: 112 PPATPAG 118
PP PAG
Sbjct: 283 PPGHPAG 289
Score = 37.4 bits (85), Expect = 0.046
Identities = 46/150 (30%), Positives = 52/150 (34%), Gaps = 28/150 (18%)
Query: 383 AEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCL 442
A AA A GA G E P A GG P P P S AG
Sbjct: 73 AGPAAPAEGAPGAAP-----EPPPAGRARPGGGGPQRPGPP--SPRRPLVPAG------- 118
Query: 443 WDLTEDVLYPHPPLARTRTLP----GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPH 498
P PP A+ R P G+ P AA+ + G EP P P + +L
Sbjct: 119 ---------PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG-PAKPAGPAALAA 168
Query: 499 PAGGGKAGGPGVAAEPGTPFSIGRFATLTL 528
AG G GPG PG G A TL
Sbjct: 169 RAGPGPGPGPGPGPGPGPGKPAGPGAAQTL 198
Score = 34.3 bits (77), Expect = 0.39
Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 15/69 (21%)
Query: 65 PASASGPGAAGPAS-------SPPPAG---PGPG----PALPAVRLSLVRLG-EPDSAGA 109
PA A+G G A PA PPPAG PG G P P+ R LV G P +A
Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
Query: 110 GEPPATPAG 118
PP AG
Sbjct: 127 RPPPEGSAG 135
Score = 33.5 bits (75), Expect = 0.66
Identities = 37/124 (29%), Positives = 43/124 (34%), Gaps = 24/124 (19%)
Query: 414 GGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAA 473
G A L PLPK + G+ Q F P PP A P PP A
Sbjct: 221 GPAALLPLPKPAAP----GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA 276
Query: 474 SSSRGGEPG--PGP------LPRSLSRSNS-------LPHPAGGGKAG-----GPGVAAE 513
++ PG GP +P + N P PA GG AG GPG AA
Sbjct: 277 PATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAA 336
Query: 514 PGTP 517
P
Sbjct: 337 APAP 340
Score = 33.5 bits (75), Expect = 0.66
Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 12/74 (16%)
Query: 452 PHPPLARTRTLP---------GTPGTTPPAASS---SRGGEPGPGPLPRSLSRSNSLPHP 499
P PP T P P PPAA+ S G P P P + + P P
Sbjct: 272 PPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGP 331
Query: 500 AGGGKAGGPGVAAE 513
A PGV AE
Sbjct: 332 GAAAAAPAPGVKAE 345
Score = 31.2 bits (69), Expect = 3.3
Identities = 38/128 (29%), Positives = 46/128 (35%), Gaps = 35/128 (27%)
Query: 4 GGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPP 63
G A P A G A + Q PG GAA + + P + Q P
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQ-----------PGPGAAAAAPAPGVKAESPKRVVQAAP 355
Query: 64 ---------GPASAS-----GPGAAG----PASSPPPAGPGPGPALP-----AVRLSLVR 100
GPAS + GP G PA+ PPPA PG LP AV SL R
Sbjct: 356 PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPA-PGTPTGLPKGAAGAVTQSLSR 414
Query: 101 LGEPDSAG 108
++G
Sbjct: 415 TPTATTSG 422
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/95 (29%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 291 AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLV 350
AFSP G++LA S D +R + + K + +L + WSPDGR + +G ++ +
Sbjct: 121 AFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGRKLASGCKNGQI 180
Query: 351 TVWSFTEGRVVARG-HGHKSWVNAVAFDPYTTRAE 384
+W + G+ V R GH W+ ++++P E
Sbjct: 181 LLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPE 215
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/123 (22%), Positives = 55/123 (44%)
Query: 256 LLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDS 315
L+ + F+++ + PL + + +N+ FSPD R +A S D ++++ +
Sbjct: 344 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 403
Query: 316 MLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVA 375
++ + + + WS D R +V+G D + VW ++ GH V AV
Sbjct: 404 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 463
Query: 376 FDP 378
+ P
Sbjct: 464 WSP 466
Score = 45.8 bits (107), Expect = 1e-04
Identities = 42/176 (23%), Positives = 70/176 (39%), Gaps = 18/176 (10%)
Query: 278 AKWAVGEG--PLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWS 335
+KW G PL+ +P+ R++A S+DG +R++ + ++ + + C+ W
Sbjct: 199 SKWITGLSWEPLHA---NPECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWG 255
Query: 336 PDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFD---PYTTRAEEAATAAGA 392
DG + + +D + VW +G + GH WVN +A T A E A A+
Sbjct: 256 GDG-LLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVN 314
Query: 393 DGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448
+ G +E + A + G R S D LW ED
Sbjct: 315 PQDLQGSLQELKERALSRYNL---------VRGQGPERLVSGSDDFTLFLWSPAED 361
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/65 (32%), Positives = 34/65 (52%)
Query: 289 EFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDD 348
+ A+S D R L S D L+V+ + L + + + V WSPDG+ V +GG+D
Sbjct: 419 QIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 478
Query: 349 LVTVW 353
+ +W
Sbjct: 479 CLRIW 483
Score = 35.8 bits (81), Expect = 0.13
Identities = 14/57 (24%), Positives = 29/57 (50%)
Query: 322 MKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378
++ + ++ V +SP G+Y+ +G D V W + GH+ WV ++++ P
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSP 166
Score = 31.2 bits (69), Expect = 3.3
Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 10/92 (10%)
Query: 291 AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGG---LLCVCW-----SPDGRYVV 342
++SPDGR LA ++G ++ +D + + ++ G + + W +P+ RYV
Sbjct: 163 SWSPDGRKLASGCKNG--QILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVA 220
Query: 343 TGGEDDLVTVWSFTEGRVVARGHGHKSWVNAV 374
+ +D V +W T GR GH V +
Sbjct: 221 SSSKDGSVRIWDTTAGRCERILTGHTQSVTCL 252
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 53.5 bits (127), Expect = 6e-07
Identities = 27/91 (29%), Positives = 47/91 (51%)
Query: 291 AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLV 350
A+SPDG++LA + DG + +F + L ++ + + + +SPD + +VT +D +
Sbjct: 155 AYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYI 214
Query: 351 TVWSFTEGRVVARGHGHKSWVNAVAFDPYTT 381
++ + GH SWV VAF P T
Sbjct: 215 KIYDVQHANLAGTLSGHASWVLNVAFCPDDT 245
Score = 51.2 bits (121), Expect = 3e-06
Identities = 25/100 (25%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Query: 281 AVGEGPLNEF--AFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDG 338
++ GP++ + AFSPD ++LA + G + +F +S + + +L + +SPDG
Sbjct: 101 SIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDG 160
Query: 339 RYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378
+Y+ +G D ++ ++ G+++ GH + ++ F P
Sbjct: 161 KYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSP 200
Score = 44.7 bits (104), Expect = 3e-04
Identities = 24/92 (26%), Positives = 39/92 (42%)
Query: 286 PLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGG 345
P+ FSPD + L S DG ++++ L G + + +L V + PD + V+
Sbjct: 192 PIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSS 251
Query: 346 EDDLVTVWSFTEGRVVARGHGHKSWVNAVAFD 377
D V VW V H+ V V ++
Sbjct: 252 SDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYN 283
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 52.4 bits (124), Expect = 1e-06
Identities = 78/347 (22%), Positives = 116/347 (33%), Gaps = 74/347 (21%)
Query: 88 GPALPAVRLSLVR----LGEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPG---- 139
GP LP V + R LG GAG+ ATP L G C +L + G
Sbjct: 9 GPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIMLLSGHEGE 68
Query: 140 --CCRRGSQRSIDLNKPIDKRIYKGTQPTCHDFNQFTAATETISLLVGFSAGQVQYLDLI 197
CC+ S + D+ I +N + + + L G S G V L
Sbjct: 69 VYCCKFHPNGSTLASAGFDRLILL--------WNVY-GDCDNYATLKGHS-GAVMELHY- 117
Query: 198 KKDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLYLYNVSHPCASAPPQYSLL 257
D S LF+ DKT + +SE+ GH N +P P
Sbjct: 118 NTDGSMLFSAST--DKTVAVW-----DSETGERVKRLKGHTSFVNSCYPARRGPQLVCTG 170
Query: 258 KQGEGFSVYAAKSKAP---------------------------RNPLAKWAVGEGPLNE- 289
++ + KA N + W + + L
Sbjct: 171 SDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYT 230
Query: 290 ----------FAFSPDGRHLACVSQDGCLRVFHFDSM--------LLRGLMKSYFGGLLC 331
+ S +G +L + D +RV+ + +G + ++ LL
Sbjct: 231 MRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLR 290
Query: 332 VCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378
WSPDG + G D V VW T R++ + GH +N VAF P
Sbjct: 291 CSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHP 337
Score = 37.4 bits (85), Expect = 0.046
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 284 EGPLNEFAFSPDGRHLACVSQDGCLRVFH-FDSMLLRGLMKSYFGGLLCVCWSPDGRYVV 342
EG + F P+G LA D + +++ + +K + G ++ + ++ DG +
Sbjct: 66 EGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLF 125
Query: 343 TGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGAD 393
+ D V VW G V R GH S+VN+ Y R G+D
Sbjct: 126 SASTDKTVAVWDSETGERVKRLKGHTSFVNSC----YPARRGPQLVCTGSD 172
>gi|62234438 Notchless gene homolog isoform b [Homo sapiens]
Length = 193
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/123 (22%), Positives = 55/123 (44%)
Query: 256 LLKQGEGFSVYAAKSKAPRNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDS 315
L+ + F+++ + PL + + +N+ FSPD R +A S D ++++ +
Sbjct: 52 LVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRT 111
Query: 316 MLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVA 375
++ + + + WS D R +V+G D + VW ++ GH V AV
Sbjct: 112 GKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVD 171
Query: 376 FDP 378
+ P
Sbjct: 172 WSP 174
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/65 (32%), Positives = 34/65 (52%)
Query: 289 EFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDD 348
+ A+S D R L S D L+V+ + L + + + V WSPDG+ V +GG+D
Sbjct: 127 QIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDK 186
Query: 349 LVTVW 353
+ +W
Sbjct: 187 CLRIW 191
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/133 (27%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 248 ASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVG--EGPLNEFAFSPDGRHLACVSQD 305
A +P LL E VY ++++ + W +G GP+ FSPDG A S D
Sbjct: 28 AFSPDGQMLLTGSEDGCVYGWETRSGQ---LLWRLGGHTGPVKFCRFSPDGHLFASASCD 84
Query: 306 GCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGH 365
+R++ ++K + + V +SPD R + +GG D V +W G+++
Sbjct: 85 CTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLV 144
Query: 366 GHKSWVNAVAFDP 378
GH+ + + F P
Sbjct: 145 GHRDSIQSSDFSP 157
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/94 (30%), Positives = 44/94 (46%)
Query: 285 GPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTG 344
G +N AFSPDG+ L S+DGC+ + S L + + G + +SPDG +
Sbjct: 22 GEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASA 81
Query: 345 GEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378
D V +W + + GH+ V V+F P
Sbjct: 82 SCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSP 115
Score = 40.8 bits (94), Expect = 0.004
Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 292 FSPDGRHLACVSQDGCLRVFHFDSM---LLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDD 348
FSP LA S D + ++ + + ++ + + C+C+S G + +G D
Sbjct: 155 FSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LLASGSWDK 213
Query: 349 LVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378
+ +W T ++ + GH +WV ++AF P
Sbjct: 214 TIHIWKPTTSSLLIQLKGHVTWVKSIAFSP 243
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 20/131 (15%)
Query: 10 SGPGAAMGDC-AEIKSQFRTREGFYKLL---PGDGAARRSGPASAQTPVPPQPPQ----- 60
S PG GD E + + G Y L PG A R+ P+ TP P
Sbjct: 720 SRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFAL 779
Query: 61 -------PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPP P S +GP+ PPP PGP A L EP AG EPP
Sbjct: 780 RARRKGPPPPPPKRLSS--VSGPSPEPPPLDESPGPKEGATGPRRRTLSEP--AGPSEPP 835
Query: 114 ATPAGLGSGGD 124
PA G D
Sbjct: 836 GPPAPAGPASD 846
Score = 38.9 bits (89), Expect = 0.016
Identities = 36/100 (36%), Positives = 40/100 (40%), Gaps = 23/100 (23%)
Query: 42 ARRSGP--------ASAQTPVPPQPP-QPPPGPASASGPGAAGP--ASSPPPAGPG--PG 88
ARR GP +S P P PP PGP GA GP + PAGP PG
Sbjct: 781 ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKE----GATGPRRRTLSEPAGPSEPPG 836
Query: 89 PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCF 128
P PA S EP P TP GS G+ + F
Sbjct: 837 PPAPAGPASDTEEEEPG------PEGTPPSRGSSGEGLPF 870
Score = 34.7 bits (78), Expect = 0.30
Identities = 28/105 (26%), Positives = 34/105 (32%), Gaps = 3/105 (2%)
Query: 18 DCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPA 77
D + + + R RE L G A + +A P P PP P +
Sbjct: 906 DTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQ 965
Query: 78 SSPPPAGPGPG---PALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119
P P P P P P L G EPPA PA L
Sbjct: 966 GVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAAL 1010
Score = 33.5 bits (75), Expect = 0.66
Identities = 32/119 (26%), Positives = 40/119 (33%), Gaps = 15/119 (12%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511
P PP R ++ G PP S E GP R+LS P G GP
Sbjct: 787 PPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASD 846
Query: 512 AEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPR 570
E P G RG+ E + GN++ KP+GP PR
Sbjct: 847 TEEEEPGPEG--------TPPSRGSSGEGLPFAEEGNLTI-------KQRPKPAGPPPR 890
Score = 33.1 bits (74), Expect = 0.86
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 11/90 (12%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA------AGPASSPPPAGPGPGPA 90
P +GA +GP +T P P PPGP + +GP + GP +PP G G
Sbjct: 813 PKEGA---TGPRR-RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRG-SSGEG 867
Query: 91 LPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
LP + + + P TP G
Sbjct: 868 LPFAEEGNLTIKQRPKPAGPPPRETPVPPG 897
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 450 LYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPG 509
++ +P + + PG P P A S G P PR RS+SL P G G
Sbjct: 673 VFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRP--GPTEGDAE 730
Query: 510 VAAEPGTPFSIGRFATLTLQERR 532
AE ++G +ATLT + R
Sbjct: 731 GEAEGPVGSTLGSYATLTRRPGR 753
Score = 30.4 bits (67), Expect = 5.6
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 26/144 (18%)
Query: 397 SGEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYR-----FGSAGQDTQF---CLWDLT 446
+ + EEEEP GT + G+ LP A G++T + G ++T ++LT
Sbjct: 844 ASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLT 903
Query: 447 EDVLYPHPPLARTR-----------TLPGTPGTTPPAASSSRGGEPG----PGPLPRSLS 491
E P R R TPG P S + G P P P P SL
Sbjct: 904 ESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLP 963
Query: 492 RSNSLPHPAGGGKAGGPGVAAEPG 515
+ +P P A P V PG
Sbjct: 964 -AQGVPTPLAPSPAMQPPVPPCPG 986
Score = 30.0 bits (66), Expect = 7.3
Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 19/102 (18%)
Query: 36 LPGDGAARRSGPASA-QTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG-------PGP 87
LP G P+ A Q PVPP PGP S + + PPA PG
Sbjct: 962 LPAQGVPTPLAPSPAMQPPVPP-----CPGPGLESSAASRWNGETEPPAAPAALLKVPGA 1016
Query: 88 GPALPAVRLSLVRLG------EPDSAGAGEPPATPAGLGSGG 123
G A V ++ +L P PP P G+ G
Sbjct: 1017 GTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG 1058
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 51.2 bits (121), Expect = 3e-06
Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 20/131 (15%)
Query: 10 SGPGAAMGDC-AEIKSQFRTREGFYKLL---PGDGAARRSGPASAQTPVPPQPPQ----- 60
S PG GD E + + G Y L PG A R+ P+ TP P
Sbjct: 802 SRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFAL 861
Query: 61 -------PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPP P S +GP+ PPP PGP A L EP AG EPP
Sbjct: 862 RARRKGPPPPPPKRLSS--VSGPSPEPPPLDESPGPKEGATGPRRRTLSEP--AGPSEPP 917
Query: 114 ATPAGLGSGGD 124
PA G D
Sbjct: 918 GPPAPAGPASD 928
Score = 38.9 bits (89), Expect = 0.016
Identities = 36/100 (36%), Positives = 40/100 (40%), Gaps = 23/100 (23%)
Query: 42 ARRSGP--------ASAQTPVPPQPP-QPPPGPASASGPGAAGP--ASSPPPAGPG--PG 88
ARR GP +S P P PP PGP GA GP + PAGP PG
Sbjct: 863 ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKE----GATGPRRRTLSEPAGPSEPPG 918
Query: 89 PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDRVCF 128
P PA S EP P TP GS G+ + F
Sbjct: 919 PPAPAGPASDTEEEEPG------PEGTPPSRGSSGEGLPF 952
Score = 34.7 bits (78), Expect = 0.30
Identities = 28/105 (26%), Positives = 34/105 (32%), Gaps = 3/105 (2%)
Query: 18 DCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPA 77
D + + + R RE L G A + +A P P PP P +
Sbjct: 988 DTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQ 1047
Query: 78 SSPPPAGPGPG---PALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119
P P P P P P L G EPPA PA L
Sbjct: 1048 GVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAAL 1092
Score = 33.5 bits (75), Expect = 0.66
Identities = 32/119 (26%), Positives = 40/119 (33%), Gaps = 15/119 (12%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511
P PP R ++ G PP S E GP R+LS P G GP
Sbjct: 869 PPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASD 928
Query: 512 AEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPR 570
E P G RG+ E + GN++ KP+GP PR
Sbjct: 929 TEEEEPGPEG--------TPPSRGSSGEGLPFAEEGNLTI-------KQRPKPAGPPPR 972
Score = 33.1 bits (74), Expect = 0.86
Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 11/90 (12%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA------AGPASSPPPAGPGPGPA 90
P +GA +GP +T P P PPGP + +GP + GP +PP G G
Sbjct: 895 PKEGA---TGPRR-RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRG-SSGEG 949
Query: 91 LPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
LP + + + P TP G
Sbjct: 950 LPFAEEGNLTIKQRPKPAGPPPRETPVPPG 979
Score = 32.7 bits (73), Expect = 1.1
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 2/83 (2%)
Query: 450 LYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPG 509
++ +P + + PG P P A S G P PR RS+SL P G G
Sbjct: 755 VFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRP--GPTEGDAE 812
Query: 510 VAAEPGTPFSIGRFATLTLQERR 532
AE ++G +ATLT + R
Sbjct: 813 GEAEGPVGSTLGSYATLTRRPGR 835
Score = 30.4 bits (67), Expect = 5.6
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 26/144 (18%)
Query: 397 SGEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYR-----FGSAGQDTQF---CLWDLT 446
+ + EEEEP GT + G+ LP A G++T + G ++T ++LT
Sbjct: 926 ASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLT 985
Query: 447 EDVLYPHPPLARTR-----------TLPGTPGTTPPAASSSRGGEPG----PGPLPRSLS 491
E P R R TPG P S + G P P P P SL
Sbjct: 986 ESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLP 1045
Query: 492 RSNSLPHPAGGGKAGGPGVAAEPG 515
+ +P P A P V PG
Sbjct: 1046 -AQGVPTPLAPSPAMQPPVPPCPG 1068
Score = 30.0 bits (66), Expect = 7.3
Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 19/102 (18%)
Query: 36 LPGDGAARRSGPASA-QTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG-------PGP 87
LP G P+ A Q PVPP PGP S + + PPA PG
Sbjct: 1044 LPAQGVPTPLAPSPAMQPPVPP-----CPGPGLESSAASRWNGETEPPAAPAALLKVPGA 1098
Query: 88 GPALPAVRLSLVRLG------EPDSAGAGEPPATPAGLGSGG 123
G A V ++ +L P PP P G+ G
Sbjct: 1099 GTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVG 1140
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 50.8 bits (120), Expect = 4e-06
Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 16/102 (15%)
Query: 38 GDGAARRSGPASAQTPVPPQPPQPPPG------PASASGPGAAGPASSPPPAGPGPG--- 88
G A GP P PP P PPPG PA+A G G P + P PA GPG
Sbjct: 161 GPPAPPAGGPPPPPGPPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGPGGGG 220
Query: 89 -------PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
A+ +L V E S G P A G GG
Sbjct: 221 AGAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGG 262
Score = 44.7 bits (104), Expect = 3e-04
Identities = 35/105 (33%), Positives = 40/105 (38%), Gaps = 25/105 (23%)
Query: 21 EIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSP 80
E++ Q R + G P + RR A P P PPPGP
Sbjct: 137 EVEQQKRQQPG-----PSEHIERRVSNAGGPPAPPAGGPPPPPGPP-------------- 177
Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPA--TPAGLGSGG 123
PP GP P P LP + G AG G PPA PA G GG
Sbjct: 178 PPPGPPPPPGLPPSGVPAAAHG----AGGGPPPAPPLPAAQGPGG 218
Score = 37.0 bits (84), Expect = 0.059
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 15/63 (23%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA----GGGKAGGPG 509
PP PG P + PAA+ GG P P P P PA GGG AG PG
Sbjct: 177 PPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAP-----------PLPAAQGPGGGGAGAPG 225
Query: 510 VAA 512
+AA
Sbjct: 226 LAA 228
Score = 36.6 bits (83), Expect = 0.078
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP-LPRSLSRSNSLPHPAGGGKAGGPGV 510
P PP T ++P P +P + +PGP + R +S + P P GG PG
Sbjct: 119 PPPPALPTWSVPNGP--SPEEVEQQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGP 176
Query: 511 AAEPGTP 517
PG P
Sbjct: 177 PPPPGPP 183
Score = 29.6 bits (65), Expect = 9.5
Identities = 51/204 (25%), Positives = 70/204 (34%), Gaps = 21/204 (10%)
Query: 371 VNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSA-----GGAPLSPLPKAG 425
V V ++ T + A G G +E+ AAG SA GG P P P
Sbjct: 67 VRGVKYNQATPNFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALEGGGPPPP-PALP 125
Query: 426 SITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSR---GGEPG 482
+ + G + ++ + + P P R + G P A G P
Sbjct: 126 TWSVPNGPSPEEVE------QQKRQQPGPSEHIERRVSNAGGPPAPPAGGPPPPPGPPPP 179
Query: 483 PGPLPRSLSRSNSLP---HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKE 539
PGP P + +P H AGGG P + A G P G A K
Sbjct: 180 PGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQG-PGGGGAGAPGLAAAIAGAKLRKV 238
Query: 540 HKRYHSLG--NISRGGSGGSGSGG 561
K+ + G + SG SG GG
Sbjct: 239 SKQEEASGGPTAPKAESGRSGGGG 262
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 50.4 bits (119), Expect = 5e-06
Identities = 37/120 (30%), Positives = 45/120 (37%), Gaps = 19/120 (15%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASG--------PGAAGPASSPPPAGPGPG 88
PG GP + P P PPGPA A+G PG G P P GP
Sbjct: 1215 PGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGA 1274
Query: 89 PALPAVRLSLVRL-GEPDSAGAGEPPATPAGLGSGGDRVCFNLGRELYFYPGCCRRGSQR 147
P P + S+ L GEP G PP P G G + +PGC + Q+
Sbjct: 1275 PGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYK----------GFPGCDGKDGQK 1324
Score = 42.4 bits (98), Expect = 0.001
Identities = 30/94 (31%), Positives = 31/94 (32%), Gaps = 12/94 (12%)
Query: 36 LPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGA------AGPASSPPPAGPGPGP 89
LPG R P P PP PP PP P PG GP P P GP P
Sbjct: 1280 LPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFP 1339
Query: 90 ALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P + G P G P P G G
Sbjct: 1340 GPPGEK------GLPGPPGRKGPTGLPGPRGEPG 1367
Score = 40.8 bits (94), Expect = 0.004
Identities = 46/186 (24%), Positives = 63/186 (33%), Gaps = 30/186 (16%)
Query: 390 AGADGERSGEEEEEEPEAA-GTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448
+G DG R + + +P + G G P SP FG++G+
Sbjct: 1062 SGIDGARGPKGNKGDPASHFGPPGPKGEPGSP-----GCPGHFGASGEQGL--------- 1107
Query: 449 VLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGP 508
P + R PG PG P SS G PG +P + + P G G P
Sbjct: 1108 -----PGIQGPRGSPGRPG---PPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDP 1159
Query: 509 GVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNIS-------RGGSGGSGSGG 561
G+ PG G L + + K H +G +G G GS G
Sbjct: 1160 GIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPG 1219
Query: 562 EKPSGP 567
P GP
Sbjct: 1220 ISPPGP 1225
Score = 38.9 bits (89), Expect = 0.016
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 6/70 (8%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPG----PGPLPRSLSRSNSLPHPAGGGKAGG 507
P L R PG+PG +PP +G G PG PGP + +P P G G
Sbjct: 1206 PGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGP 1265
Query: 508 PGVAAEPGTP 517
PG G P
Sbjct: 1266 PGPDGPRGAP 1275
Score = 37.0 bits (84), Expect = 0.059
Identities = 31/95 (32%), Positives = 34/95 (35%), Gaps = 15/95 (15%)
Query: 33 YKLLPG-DGAARRSGPASAQTPVPPQPPQPPPGPASASG-PGAAGPASSPPPAG-PGPG- 88
YK PG DG + GP P P PPG G PG GP P P G PGP
Sbjct: 1311 YKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPA 1370
Query: 89 -----------PALPAVRLSLVRLGEPDSAGAGEP 112
P P +R +G P G P
Sbjct: 1371 DVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGP 1405
Score = 36.2 bits (82), Expect = 0.10
Identities = 36/122 (29%), Positives = 40/122 (32%), Gaps = 17/122 (13%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDG--AARRSGPASAQTPVPPQPPQPP 62
G G GP G + R + +PG + R P P P P P
Sbjct: 789 GCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSP 848
Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122
P PG GP P PAG P LP G P GA PP P G
Sbjct: 849 GAPGGKGQPGDVGP---PGPAGMKGLPGLP---------GRP---GAHGPPGLPGIPGPF 893
Query: 123 GD 124
GD
Sbjct: 894 GD 895
Score = 35.0 bits (79), Expect = 0.23
Identities = 52/200 (26%), Positives = 63/200 (31%), Gaps = 71/200 (35%)
Query: 390 AGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDV 449
AG G+ + E+ G G G PL P KAG + G G
Sbjct: 592 AGEKGDPGPPGDHEDATPGGKGFPG--PLGPPGKAGPV----GPPGLG------------ 633
Query: 450 LYPHPPLARTRT-LPGTPGTTPPAASSSRGGE--------PG----PG----PLPRSLSR 492
+P PP R +PG PG P + G+ PG PG P P+
Sbjct: 634 -FPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPG 692
Query: 493 SNSLPHPAGG----GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGN 548
P +G G+ G PG A PG P
Sbjct: 693 PQGAPGLSGSDGHKGRPGTPGTAEIPGPPGF----------------------------- 723
Query: 549 ISRGGSGGSGSGGEKPSGPV 568
RG G G GGEK S PV
Sbjct: 724 --RGDMGDPGFGGEKGSSPV 741
Score = 35.0 bits (79), Expect = 0.23
Identities = 35/129 (27%), Positives = 42/129 (32%), Gaps = 3/129 (2%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522
PG PG P G PGP LP S+ P G G PG PG P G
Sbjct: 1257 PGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG--EPGDCGLPGPPGPPGPPGPPGYKGF 1314
Query: 523 FATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGTA 582
++ + H G G G G K +P R +P
Sbjct: 1315 PGCDGKDGQKGPVGFPGPQGPHGFPG-PPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVD 1373
Query: 583 LCPRIHEVP 591
CPRI +P
Sbjct: 1374 DCPRIPGLP 1382
Score = 33.5 bits (75), Expect = 0.66
Identities = 28/87 (32%), Positives = 32/87 (36%), Gaps = 18/87 (20%)
Query: 55 PPQPPQPP-----PGPASASG----PGAAGPASSP----PPAGPGP-----GPALPAVRL 96
PP P P PG ASG PG GP SP PP GP +P +R
Sbjct: 1083 PPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRG 1142
Query: 97 SLVRLGEPDSAGAGEPPATPAGLGSGG 123
+G+P G P P G G
Sbjct: 1143 QPGEMGDPGPRGLQGDPGIPGPPGIKG 1169
Score = 33.5 bits (75), Expect = 0.66
Identities = 34/104 (32%), Positives = 36/104 (34%), Gaps = 23/104 (22%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQ-----FRTREGFYKLLPGDGAARRSGPASAQTP------ 53
G G GP A + DC I R EG L G SGP P
Sbjct: 1361 GPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGL---PGMRGPSGPGCKGEPGLDGRR 1417
Query: 54 -VPPQPPQP-PPGPASASG-------PGAAGPASSPPPAGPGPG 88
V P P PPG +G PG GP P P G GPG
Sbjct: 1418 GVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPG 1461
Score = 33.1 bits (74), Expect = 0.86
Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 23/84 (27%)
Query: 63 PGPASASG----PGAAGP----------ASSPPPAGPGPGPALPAVRLS---------LV 99
PGP G PG GP A P P GP P LP + S L
Sbjct: 465 PGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLG 524
Query: 100 RLGEPDSAGAGEPPATPAGLGSGG 123
G+P GA PP P G+ G
Sbjct: 525 TKGDPGPPGAEGPPGLPGKHGASG 548
Score = 33.1 bits (74), Expect = 0.86
Identities = 37/128 (28%), Positives = 40/128 (31%), Gaps = 19/128 (14%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
G G GP G F +G L DG R G TP + P PP
Sbjct: 677 GPPGFDGPPGPKG--------FPGPQGAPGLSGSDGHKGRPG-----TPGTAEIPGPPGF 723
Query: 65 PASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEP-----PATPAGL 119
PG G S P PGP P P V G+P G P P
Sbjct: 724 RGDMGDPGFGGEKGSSPVGPPGP-PGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782
Query: 120 GSGGDRVC 127
G GD C
Sbjct: 783 GPRGDPGC 790
Score = 33.1 bits (74), Expect = 0.86
Identities = 33/106 (31%), Positives = 38/106 (35%), Gaps = 15/106 (14%)
Query: 411 GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTP 470
G G +P+ P GS G GQ + D + H R L G PG
Sbjct: 734 GEKGSSPVGPPGPPGSP----GVNGQK------GIPGDPAFGHLGPPGKRGLSGVPGIKG 783
Query: 471 PAASSSRGGEPGPGPLPRSLSRSNSLPHPAG-GGKAGGPGVAAEPG 515
P G GP +P L L P G G AG PGV PG
Sbjct: 784 PRGDPGCPGAEGPAGIPGFL----GLKGPKGREGHAGFPGVPGPPG 825
Score = 33.1 bits (74), Expect = 0.86
Identities = 47/168 (27%), Positives = 51/168 (30%), Gaps = 51/168 (30%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTRE-GFYKLLPGDGAARRSGPASAQTPVPPQPPQPP- 62
G G G GD Q R E G Y G R P P PP PP PP
Sbjct: 978 GPPGDDGFPGERGDKGTPGMQGRRGEPGRY----GPPGFHRGEPGEKGQPGPPGPPGPPG 1033
Query: 63 ----------------------PGPASASG-PGAAGPASS---------PP-----PAGP 85
PGP SG GA GP + PP P P
Sbjct: 1034 STGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093
Query: 86 G-PG-------PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125
G PG LP ++ G P G+ PP P G G R
Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLR 1141
Score = 32.7 bits (73), Expect = 1.1
Identities = 29/99 (29%), Positives = 33/99 (33%), Gaps = 19/99 (19%)
Query: 36 LPGDGAARRSGPASAQTPVPPQPPQPPPGPASASG----------PGAAGPASSPPPAGP 85
+P G+ GP Q P+ P PGP SG PGAAG P G
Sbjct: 58 VPEKGSRGPPGPPGPQGPIGPLGA---PGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGV 114
Query: 86 GPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124
P L + G P G P GS GD
Sbjct: 115 PGFPGLDGIP------GHPGPPGPRGKPGMSGHNGSRGD 147
Score = 32.3 bits (72), Expect = 1.5
Identities = 23/68 (33%), Positives = 27/68 (39%), Gaps = 6/68 (8%)
Query: 62 PPGPASASGPGAAGPASSPPPAGP--GPG----PALPAVRLSLVRLGEPDSAGAGEPPAT 115
PPG SG GA G P GP PG P P ++ L +G+P G P
Sbjct: 286 PPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGD 345
Query: 116 PAGLGSGG 123
P G G
Sbjct: 346 PGNRGHPG 353
Score = 32.3 bits (72), Expect = 1.5
Identities = 21/54 (38%), Positives = 21/54 (38%), Gaps = 2/54 (3%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG-GGKAGGPGVAAEPG 515
PG PG P G PGP PR L P G G G PG EPG
Sbjct: 884 PGLPGIPGPFGDDGLPGPPGPKG-PRGLPGFPGFPGERGKPGAEGCPGAKGEPG 936
Score = 32.3 bits (72), Expect = 1.5
Identities = 26/77 (33%), Positives = 28/77 (36%), Gaps = 14/77 (18%)
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLP-HPAGGGKAG--- 506
+P PP + LPG PG P GEPGP R LP P G G
Sbjct: 1338 FPGPP--GEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMG 1395
Query: 507 --------GPGVAAEPG 515
GPG EPG
Sbjct: 1396 LPGMRGPSGPGCKGEPG 1412
Score = 32.0 bits (71), Expect = 1.9
Identities = 37/126 (29%), Positives = 40/126 (31%), Gaps = 18/126 (14%)
Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA-----AEPGT 516
LPG PG S GG GP P P G G PGV +PG
Sbjct: 194 LPGLPG------SWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGE 247
Query: 517 PFSIGRFATLTLQERRDRGAEKEHKRYHSL-------GNISRGGSGGSGSGGEKPSGPVP 569
G L E D K K + G R G G G+ GEK P
Sbjct: 248 VGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFP 307
Query: 570 RSRLDP 575
R DP
Sbjct: 308 GPRGDP 313
Score = 31.2 bits (69), Expect = 3.3
Identities = 37/139 (26%), Positives = 43/139 (30%), Gaps = 13/139 (9%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG----DGAARRSGPASAQTPVPPQPPQ 60
GA G G A GD + + E PG G+ R G A + P
Sbjct: 545 GASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDH 604
Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
P PG GP P GP PG P G P G P G
Sbjct: 605 EDATPGGKGFPGPLGPPGKAGPVGP-PGLGFPGPPGERGHPGVPGHPGVRGPDGLK---G 660
Query: 121 SGGDRVCFNLGRELYFYPG 139
GD + N+ YPG
Sbjct: 661 QKGDTISCNV-----TYPG 674
Score = 30.8 bits (68), Expect = 4.3
Identities = 28/96 (29%), Positives = 32/96 (33%), Gaps = 10/96 (10%)
Query: 40 GAARRSGPASAQTPVPPQPPQPP-----PGPASASG-----PGAAGPASSPPPAGPGPGP 89
G R G A A PP P P PG A G PG G SP G
Sbjct: 391 GLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQ 450
Query: 90 ALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125
LP + +G P G P G G G++
Sbjct: 451 GLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEK 486
Score = 30.8 bits (68), Expect = 4.3
Identities = 32/112 (28%), Positives = 39/112 (34%), Gaps = 10/112 (8%)
Query: 459 TRTLPGTPGTT-PPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515
T+ PG PG PP G G PG + S H G G PG +PG
Sbjct: 525 TKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPG 584
Query: 516 TPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567
+ G E+ D G +H+ G G G G G P GP
Sbjct: 585 SHGRDGHAG-----EKGDPGPPGDHEDATPGGKGFPGPLGPPGKAG--PVGP 629
Score = 30.8 bits (68), Expect = 4.3
Identities = 21/62 (33%), Positives = 24/62 (38%), Gaps = 5/62 (8%)
Query: 462 LPGTPGTTPPAASSSRGGEPG-PGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSI 520
+PG G P G PG PGP S R P G+ G PG PG P
Sbjct: 799 IPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGA----PGIPGQPGLPGYPGSPGAPGGK 854
Query: 521 GR 522
G+
Sbjct: 855 GQ 856
Score = 30.8 bits (68), Expect = 4.3
Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 7/60 (11%)
Query: 463 PGTPGTTPPAASSSRG-----GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG PG PP S RG G+PG P S P G G G+ PG P
Sbjct: 818 PGVPG--PPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLP 875
Score = 30.8 bits (68), Expect = 4.3
Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 18/78 (23%)
Query: 463 PGTPGTT-PPAASSSRG-----------GEPGPGPLPRSLSRSNSLPHPAG-----GGKA 505
PG PG PP ++ RG GEPG P P S + P G
Sbjct: 1023 PGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPG-SPGPPGFSGIDGARGPKGNKGDPASHF 1081
Query: 506 GGPGVAAEPGTPFSIGRF 523
G PG EPG+P G F
Sbjct: 1082 GPPGPKGEPGSPGCPGHF 1099
Score = 30.0 bits (66), Expect = 7.3
Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 4/66 (6%)
Query: 59 PQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSA-GAGEPPATPA 117
P PPG G AG P P G P LP + G PDSA G P +P
Sbjct: 386 PPGPPGLLGRPGEACAGMIGPPGPQG---FPGLPGLPGEAGIPGRPDSAPGKPGKPGSPG 442
Query: 118 GLGSGG 123
G+ G
Sbjct: 443 LPGAPG 448
Score = 30.0 bits (66), Expect = 7.3
Identities = 30/94 (31%), Positives = 34/94 (36%), Gaps = 8/94 (8%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQP----PPGPASASGP-GAAGPASSPPPAGPGPGPAL 91
PGD GPA + +P P +P PPG GP G G P P GP P
Sbjct: 857 PGDVGP--PGPAGMKG-LPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGF 913
Query: 92 PAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125
P + G GA P G GDR
Sbjct: 914 PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDR 947
Score = 29.6 bits (65), Expect = 9.5
Identities = 42/138 (30%), Positives = 47/138 (34%), Gaps = 30/138 (21%)
Query: 452 PHPPLAR-TRTLPGTPGTT----PPAASSSRGGEPGPG-------PLPRSLSRSNSLPHP 499
P PP + R LPG PG P A G + PG P R L + P
Sbjct: 899 PGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGP 958
Query: 500 AGG----------GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI 549
G G G PG + G P G T +Q RR E RY G
Sbjct: 959 PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRG-----EPGRYGPPG-F 1012
Query: 550 SRGGSGGSGSGGEKPSGP 567
RG G G G P GP
Sbjct: 1013 HRGEPGEKGQPG--PPGP 1028
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 50.1 bits (118), Expect = 7e-06
Identities = 44/127 (34%), Positives = 45/127 (35%), Gaps = 33/127 (25%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62
A GA G +GP A G GAA R GP P P P
Sbjct: 861 AKGARGSAGPPGATGF--------------------PGAAGRVGPPGPSGNAGPPGPPGP 900
Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEP---PATPAG 118
G GP G GPA P GP PGP PA GE S GA P P TP
Sbjct: 901 AGKEGGKGPRGETGPAGRPGEVGP-PGPPGPA--------GEKGSPGADGPAGAPGTPGP 951
Query: 119 LGSGGDR 125
G G R
Sbjct: 952 QGIAGQR 958
Score = 44.7 bits (104), Expect = 3e-04
Identities = 45/142 (31%), Positives = 49/142 (34%), Gaps = 22/142 (15%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPVPPQPPQP-- 61
G G GP A GD E + PGD G GPA P P QP
Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP-PGADGQPGA 825
Query: 62 --PPGPASASG----PGAAGPASSPPPAGPGPGPALPAVRLS------------LVRLGE 103
PG A A G PG AGPA P P G P R S R+G
Sbjct: 826 KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 885
Query: 104 PDSAGAGEPPATPAGLGSGGDR 125
P +G PP P G G +
Sbjct: 886 PGPSGNAGPPGPPGPAGKEGGK 907
Score = 43.9 bits (102), Expect = 5e-04
Identities = 38/111 (34%), Positives = 43/111 (38%), Gaps = 24/111 (21%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQ----FRTREGFYKLL--PGD-GAARRSGPASAQTPVPPQ 57
GA G +GP GD E Q + GF L PG G+ GP+ A P P+
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141
Query: 58 PPQPP------------PGPASASGP----GAAGPASSPPPAGPGPGPALP 92
P PGP GP G AGP P P GP PGP P
Sbjct: 1142 GPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGP-PGPPGP 1191
Score = 43.1 bits (100), Expect = 8e-04
Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 23/127 (18%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
GA G +GP G GF + G A GP ++ P + PPG
Sbjct: 326 GATGAAGPPGPTGPAGP--------PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPG 377
Query: 65 PASASGPGAAGPASSPPPAGPG----PG----PALPAVRLSLVRLGEPDSAGAGEPPATP 116
PA A+GP A P + P G PG P P R G G G PP
Sbjct: 378 PAGAAGP-AGNPGADGQPGAKGANGAPGIAGAPGFPGAR------GPSGPQGPGGPPGPK 430
Query: 117 AGLGSGG 123
G G
Sbjct: 431 GNSGEPG 437
Score = 42.7 bits (99), Expect = 0.001
Identities = 55/187 (29%), Positives = 70/187 (37%), Gaps = 27/187 (14%)
Query: 391 GADGERSGEEEEEEPEAAGT----GSAG--GAPLSPLPKAGSITYRFGSAGQDTQFCLWD 444
G GER G P A G G AG G+P PK G AG+
Sbjct: 482 GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSP-----GEAGRPG------ 530
Query: 445 LTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGK 504
E L L + PG G T P + + G PGP P + ++ + P G
Sbjct: 531 --EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGA 588
Query: 505 AGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK- 563
AG PG A E G P G A + + GA+ G RG G +GS G +
Sbjct: 589 AGEPGKAGERGVPGPPG--AVGPAGKDGEAGAQGPPGPAGPAG--ERGEQGPAGSPGFQG 644
Query: 564 ---PSGP 567
P+GP
Sbjct: 645 LPGPAGP 651
Score = 41.6 bits (96), Expect = 0.002
Identities = 37/137 (27%), Positives = 46/137 (33%), Gaps = 16/137 (11%)
Query: 381 TRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQF 440
T A+ G G EE + A G G P P + G + F A
Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA------ 498
Query: 441 CLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA 500
+ V P P G+PG P S G PG LP + + S P
Sbjct: 499 ------DGVAGPKGPAGER----GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548
Query: 501 GGGKAGGPGVAAEPGTP 517
GK G PG A + G P
Sbjct: 549 PDGKTGPPGPAGQDGRP 565
Score = 41.6 bits (96), Expect = 0.002
Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 6/125 (4%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQPPP 63
GA G GP G + + E + LPG G + GP+ A P P PP
Sbjct: 944 GAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003
Query: 64 GPASASGPGAAGPASSPPPAG-PG--PGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
G A PG +G +P G PG P R G P + GA P G
Sbjct: 1004 GLAGP--PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAG 1061
Query: 121 SGGDR 125
GDR
Sbjct: 1062 KSGDR 1066
Score = 41.2 bits (95), Expect = 0.003
Identities = 43/142 (30%), Positives = 48/142 (33%), Gaps = 28/142 (19%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-------------DGAARRSGPASAQ 51
GA+G +G A G Q E LPG DG+ + G
Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766
Query: 52 TPVPPQPPQPPPGPASASGP----------GAAGPASSPPPAGPGPGPALPAVRLSLVRL 101
P+ P P PG SGP GA G P P GP P
Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826
Query: 102 GEPDSAG----AGEP-PATPAG 118
GEP AG AG P PA PAG
Sbjct: 827 GEPGDAGAKGDAGPPGPAGPAG 848
Score = 40.4 bits (93), Expect = 0.005
Identities = 43/129 (33%), Positives = 49/129 (37%), Gaps = 18/129 (13%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRG---GEPGP-GPL-------PRSLSRSNSLPHPAG- 501
P A R +PG PG PA G PGP GP P LP PAG
Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651
Query: 502 GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNIS-RGGSGGSGSG 560
G+AG PG E G P +G A R +RG E G RG +G G+
Sbjct: 652 PGEAGKPG---EQGVPGDLG--APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGND 706
Query: 561 GEKPSGPVP 569
G K P
Sbjct: 707 GAKGDAGAP 715
Score = 39.3 bits (90), Expect = 0.012
Identities = 33/116 (28%), Positives = 36/116 (31%), Gaps = 37/116 (31%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPP---------------------------PGPASAS 69
P R P P PP PP PP PGP S
Sbjct: 125 PAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS 184
Query: 70 GP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124
GP G GP +P P G P P GEP ++G P P G GD
Sbjct: 185 GPRGLPGPPGAPGPQGFQGPPGEP---------GEPGASGPMGPRGPPGPPGKNGD 231
Score = 39.3 bits (90), Expect = 0.012
Identities = 36/130 (27%), Positives = 44/130 (33%), Gaps = 20/130 (15%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQ----------TP 53
GA+G +GP G+ + + LPG+ G GPA A+ P
Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334
Query: 54 VPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113
P P PP P + G AGP GP P G P AGA P
Sbjct: 335 GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEP---------GPPGPAGAAGPA 385
Query: 114 ATPAGLGSGG 123
P G G
Sbjct: 386 GNPGADGQPG 395
Score = 39.3 bits (90), Expect = 0.012
Identities = 40/129 (31%), Positives = 48/129 (37%), Gaps = 29/129 (22%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
G G +GP G +EG G G +GPA V P P PG
Sbjct: 887 GPSGNAGPPGPPGPAG--------KEG------GKGPRGETGPAGRPGEVGPPGP---PG 929
Query: 65 PASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRL-------GEPDSAGAGEPPATP 116
PA G PGA GPA +P PGP A + +V L G P G P
Sbjct: 930 PAGEKGSPGADGPAGAPGT----PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985
Query: 117 AGLGSGGDR 125
G+ G+R
Sbjct: 986 GPSGASGER 994
Score = 38.9 bits (89), Expect = 0.016
Identities = 41/132 (31%), Positives = 46/132 (34%), Gaps = 21/132 (15%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQ-------TPVP- 55
G +G GP G+ E + + K PG G GPA + P P
Sbjct: 419 GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPT 478
Query: 56 --PQPPQPPPGPASASGPGAAGPASSPPPAGP--GPGPALPAVRLSLVRLGEPDSAGAGE 111
P PP GP S PGA G A PAG PGPA P G P AG
Sbjct: 479 GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPK--------GSPGEAGRPG 530
Query: 112 PPATPAGLGSGG 123
P G G
Sbjct: 531 EAGLPGAKGLTG 542
Score = 38.1 bits (87), Expect = 0.027
Identities = 39/117 (33%), Positives = 42/117 (35%), Gaps = 30/117 (25%)
Query: 37 PG-DGAARRSGPASAQTPVPPQPPQPP-----------PGPASASG-------------P 71
PG DG GPA P PP PP PGP A+G P
Sbjct: 547 PGPDGKTGPPGPAGQDGR--PGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604
Query: 72 GAAGPASSPPPAGP--GPGPALPA-VRLSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125
GA GPA AG PGPA PA R G P G P P G G++
Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661
Score = 37.7 bits (86), Expect = 0.035
Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 7/88 (7%)
Query: 43 RRSGPASAQTPVPPQPPQPPPGPASASGP-GAAGPASSPP------PAGPGPGPALPAVR 95
+ +G S P+ P P+ PGP A GP G GP P P GP P P
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKN 229
Query: 96 LSLVRLGEPDSAGAGEPPATPAGLGSGG 123
G+P G PP G G
Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGARGLPG 257
Score = 37.7 bits (86), Expect = 0.035
Identities = 39/125 (31%), Positives = 45/125 (36%), Gaps = 17/125 (13%)
Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62
G G GP A G A + + GF L DGA +GPA P P
Sbjct: 242 GERGPPGPQGARGLPGTAGLPGM-KGHRGFSGL---DGAKGDAGPAG--------PKGEP 289
Query: 63 PGPASASGPGAAGPASSPPPAG-PG-PGPALPAVRLSLV-RLGEPDSAGAGEPPATPAGL 119
P PG GP P G PG PGPA G P G PP P +
Sbjct: 290 GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349
Query: 120 GSGGD 124
G+ G+
Sbjct: 350 GAKGE 354
Score = 37.7 bits (86), Expect = 0.035
Identities = 40/118 (33%), Positives = 43/118 (36%), Gaps = 7/118 (5%)
Query: 5 GAEGGSGPGAAMGD---CAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61
GA+G GP G E + E LPG R GP S P
Sbjct: 446 GAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP-PGERGGPGSRGFP-GADGVAG 503
Query: 62 PPGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAG 118
P GPA G PG AGP SP AG LP + G P G PP PAG
Sbjct: 504 PKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG-PAG 560
Score = 35.0 bits (79), Expect = 0.23
Identities = 33/111 (29%), Positives = 41/111 (36%), Gaps = 8/111 (7%)
Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519
R LPG PG P GEPG P + P GK G G A +PG P
Sbjct: 187 RGLPGPPGAPGPQGFQGPPGEPGE---PGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE 243
Query: 520 ---IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567
G L K H+ + L ++G +G +G GE P P
Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDG-AKGDAGPAGPKGE-PGSP 292
Score = 35.0 bits (79), Expect = 0.23
Identities = 46/132 (34%), Positives = 49/132 (37%), Gaps = 36/132 (27%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQ-TPVPPQP--PQ 60
G G GP A G + GF PG GAA G A + P PP P
Sbjct: 563 GRPGPPGPPGARGQAGVM--------GF----PGPKGAAGEPGKAGERGVPGPPGAVGPA 610
Query: 61 PPPGPASASGP-GAAGPASS---PPPAG-PG----PGPALPAVRLSLVRLGEPDSAGAGE 111
G A A GP G AGPA PAG PG PGPA G P AG
Sbjct: 611 GKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA-----------GPPGEAGKPG 659
Query: 112 PPATPAGLGSGG 123
P LG+ G
Sbjct: 660 EQGVPGDLGAPG 671
Score = 34.7 bits (78), Expect = 0.30
Identities = 43/140 (30%), Positives = 51/140 (36%), Gaps = 34/140 (24%)
Query: 391 GADGERSGEEEEEEPEAAGT----GSAGGA-PLSPLPKAGSITYRF--GSAGQDTQFCLW 443
GADG+ + E + A G G AG A P P+ G+ + GSAG
Sbjct: 818 GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAG-------- 869
Query: 444 DLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGP-GPLPRSLSRSNSLPHPAGG 502
PP A PG G P S G PGP GP + + P G
Sbjct: 870 ----------PPGATG--FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG-----PRGE 912
Query: 503 -GKAGGPGVAAEPGTPFSIG 521
G AG PG PG P G
Sbjct: 913 TGPAGRPGEVGPPGPPGPAG 932
Score = 33.9 bits (76), Expect = 0.50
Identities = 36/106 (33%), Positives = 41/106 (38%), Gaps = 25/106 (23%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG-GKAGGPGVAAEPGTPFSIG 521
PG PG PA S GE GP PAG G G G A G G
Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPA-------------GPAGPVGPVGARGPAGPQGPRGDKG 1097
Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK-PSG 566
E+ DRG K H+ + L +G G GS GE+ PSG
Sbjct: 1098 ETG-----EQGDRGI-KGHRGFSGL----QGPPGPPGSPGEQGPSG 1133
Score = 33.1 bits (74), Expect = 0.86
Identities = 30/104 (28%), Positives = 33/104 (31%), Gaps = 26/104 (25%)
Query: 46 GPASAQTPVPPQPPQPPPG----PASASGPGAAGPASSPPPAGPG--------------- 86
GP P P+ P PPG P PG GP P P G G
Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171
Query: 87 ------PGPALPAVRLSLV-RLGEPDSAGAGEPPATPAGLGSGG 123
PGP P+ L G P G PP P G+ G
Sbjct: 172 TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASG 215
Score = 33.1 bits (74), Expect = 0.86
Identities = 39/133 (29%), Positives = 44/133 (33%), Gaps = 32/133 (24%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG----PASAQTPVPPQPPQ 60
GA+G +GP G+ R G G A R G P + P P
Sbjct: 497 GADGVAGPKGPAGE--------RGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548
Query: 61 P-----PPGPASASGPGAAGPASSPPPAGPG-----PGPALPAVRLSLVRLGEPDSAGAG 110
P PPGPA G GP P G PGP A GEP AG
Sbjct: 549 PDGKTGPPGPAGQDG--RPGPPGPPGARGQAGVMGFPGPKGAA--------GEPGKAGER 598
Query: 111 EPPATPAGLGSGG 123
P P +G G
Sbjct: 599 GVPGPPGAVGPAG 611
Score = 32.7 bits (73), Expect = 1.1
Identities = 19/53 (35%), Positives = 21/53 (39%), Gaps = 9/53 (16%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515
PG PG P+ GG PGP + NS P G G G EPG
Sbjct: 409 PGFPGARGPSGPQGPGGPPGP--------KGNS-GEPGAPGSKGDTGAKGEPG 452
Score = 32.7 bits (73), Expect = 1.1
Identities = 35/110 (31%), Positives = 42/110 (38%), Gaps = 16/110 (14%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG-GGKAGGPGVAAEPGTPFSIGR 522
G PG P+ +S G PGP P L P G G+ G PG PG S G
Sbjct: 980 GEPGKQGPSGASGERGPPGPMGPP-------GLAGPPGESGREGAPGAEGSPGRDGSPG- 1031
Query: 523 FATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK----PSGPV 568
A E G + G + G +G SG GE P+GPV
Sbjct: 1032 -AKGDRGETGPAGPPGAPGAPGAPGPV--GPAGKSGDRGETGPAGPAGPV 1078
Score = 32.0 bits (71), Expect = 1.9
Identities = 25/93 (26%), Positives = 33/93 (35%), Gaps = 7/93 (7%)
Query: 39 DGAARRSGPASAQTPVPPQPPQPPPGPASASG-------PGAAGPASSPPPAGPGPGPAL 91
DG A + G + P PQ + PG A G G G PAGP P
Sbjct: 232 DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291
Query: 92 PAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124
P + ++G G P P G+ G+
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGN 324
Score = 32.0 bits (71), Expect = 1.9
Identities = 17/58 (29%), Positives = 21/58 (36%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
G G+ P G PGP + P G G PG+A PG P + G
Sbjct: 359 GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416
Score = 32.0 bits (71), Expect = 1.9
Identities = 35/129 (27%), Positives = 43/129 (33%), Gaps = 26/129 (20%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPVPPQPPQPPP 63
G +G GP G+ + Q +PGD GA SG + + Q PP
Sbjct: 641 GFQGLPGPAGPPGEAGKPGEQG---------VPGDLGAPGPSGARGERGFPGERGVQGPP 691
Query: 64 GPASASGP-------GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATP 116
GPA G GA G A +P G P L G P GA P
Sbjct: 692 GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ---------GMPGERGAAGLPGPK 742
Query: 117 AGLGSGGDR 125
G G +
Sbjct: 743 GDRGDAGPK 751
Score = 32.0 bits (71), Expect = 1.9
Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 12/67 (17%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRS--NSLPHPAG----------GGKAGGPGV 510
PG+PG P+ +S G GP + + N LP P G G G PG
Sbjct: 1123 PGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGP 1182
Query: 511 AAEPGTP 517
PG P
Sbjct: 1183 PGPPGPP 1189
Score = 31.6 bits (70), Expect = 2.5
Identities = 30/114 (26%), Positives = 33/114 (28%), Gaps = 2/114 (1%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522
PG PG A G+PG P P G AG PG G P + G
Sbjct: 805 PGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG- 863
Query: 523 FATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPA 576
A + G R G G G K G PR PA
Sbjct: 864 -ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/101 (34%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRT-REGF--YKLLPG-DGAARRSGPASAQTPV-PPQPP 59
GA G GP MG + REG + PG DG+ G P PP P
Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048
Query: 60 QPP--PGPASASGP----GAAGPASSPPPAGP--GPGPALP 92
P PGP +G G GPA P GP GPA P
Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP 1089
Score = 30.8 bits (68), Expect = 4.3
Identities = 58/214 (27%), Positives = 69/214 (32%), Gaps = 49/214 (22%)
Query: 391 GADGERSGEEEEEEPEAAGT-GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDV 449
G++G + E P AG G AG P A G AG
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGA------------- 408
Query: 450 LYPHPPLARTRTLPGTPGTTP--------PAASSSRG-----GEPG-------PGPLPRS 489
P P AR + P PG P P A S+G GEPG PGP
Sbjct: 409 --PGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466
Query: 490 LSR-SNSLPHPAG----GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYH 544
R + P P G G+ GGPG PG G +RG+
Sbjct: 467 GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG-----PKGPAGERGSPGPAGPKG 521
Query: 545 SLGNISRGGSGG-SGSGG--EKPSGPVPRSRLDP 575
S G R G G G+ G P P P + P
Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGP 555
Score = 30.4 bits (67), Expect = 5.6
Identities = 36/124 (29%), Positives = 45/124 (36%), Gaps = 37/124 (29%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG-------GKAGGP---GVAA 512
PG+PG + G+ GP LP R + P PAG G AG P G A
Sbjct: 289 PGSPG------ENGAPGQMGPRGLPGERGRPGA-PGPAGARGNDGATGAAGPPGPTGPAG 341
Query: 513 EPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSR 572
PG P ++G + + G + RG G G GE P P P
Sbjct: 342 PPGFPGAVG--------AKGEAGPQG-----------PRGSEGPQGVRGE-PGPPGPAGA 381
Query: 573 LDPA 576
PA
Sbjct: 382 AGPA 385
Score = 30.4 bits (67), Expect = 5.6
Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 23/120 (19%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG-GKAGGPGVAAEPGTPFSIG 521
PG G PA G+PG +P L P P+G G+ G PG G P G
Sbjct: 640 PGFQGLPGPAGPPGEAGKPGEQGVPGDL----GAPGPSGARGERGFPGERGVQGPPGPAG 695
Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNI-------SRGGSGGSGSGGEKPSGPVPRSRLD 574
RGA + G+ S+G G G GE+ + +P + D
Sbjct: 696 -----------PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744
Score = 30.4 bits (67), Expect = 5.6
Identities = 18/58 (31%), Positives = 20/58 (34%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
G+PG + G PGP P S G G PG EPG P G
Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812
Score = 30.4 bits (67), Expect = 5.6
Identities = 36/131 (27%), Positives = 38/131 (29%), Gaps = 55/131 (41%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62
A GA G GP GD E +GPA PV P + P
Sbjct: 1050 APGAPGPVGPAGKSGDRGE-----------------------TGPAGPAGPVGPVGARGP 1086
Query: 63 PGPASASG----------------------PGAAGPASSPPPAGP--GPGPALPAVRLSL 98
GP G G GP SP GP GPA P
Sbjct: 1087 AGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR----- 1141
Query: 99 VRLGEPDSAGA 109
G P SAGA
Sbjct: 1142 ---GPPGSAGA 1149
Score = 30.4 bits (67), Expect = 5.6
Identities = 21/64 (32%), Positives = 23/64 (35%), Gaps = 9/64 (14%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRS-----NSLPHPAG----GGKAGGPGVAAE 513
PG PG+ S G GP P S N LP P G G+ G G
Sbjct: 1120 PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP 1179
Query: 514 PGTP 517
PG P
Sbjct: 1180 PGPP 1183
Score = 29.6 bits (65), Expect = 9.5
Identities = 24/76 (31%), Positives = 25/76 (32%), Gaps = 16/76 (21%)
Query: 462 LPGTPGTTPPAASSSRGGEPGPG---------------PLPRSLSRSNSLPHPAGG-GKA 505
LPG PG P GG P P P S LP P G G
Sbjct: 140 LPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQ 199
Query: 506 GGPGVAAEPGTPFSIG 521
G G EPG P + G
Sbjct: 200 GFQGPPGEPGEPGASG 215
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 50.1 bits (118), Expect = 7e-06
Identities = 28/66 (42%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 47 PASAQTPVPPQPPQPPPGPASASGPGAAGP-----ASSPPPAGPGPGPALPAVRLSLVRL 101
P T PP PP PPP PASA+ P + P A+ P PAG P PAL A +
Sbjct: 74 PPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPF 133
Query: 102 GEPDSA 107
DSA
Sbjct: 134 PHGDSA 139
Score = 34.3 bits (77), Expect = 0.39
Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 17/70 (24%)
Query: 57 QPPQPPPGPASASGPGAAGPASSPPPAGPGP--GPALPAVRLSLVRLGEPDSAGAGEPPA 114
QPP PPP S PPPA P G LPA P + AG PA
Sbjct: 4 QPPPPPPQQQQQQ-----QQLSPPPPAALAPVSGVVLPA----------PPAVSAGSSPA 48
Query: 115 TPAGLGSGGD 124
G G+GG+
Sbjct: 49 GSPGGGAGGE 58
Score = 33.5 bits (75), Expect = 0.66
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 449 VLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGP 508
+L+P PP P P PP +S+ GP P P L+ P PAGG
Sbjct: 68 LLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGP-PAPPGLAAG---PGPAGGAPTPAL 123
Query: 509 GVAAEPGTPFSIGRFATLTLQER 531
+ PF G A L QE+
Sbjct: 124 VAGSSAAAPFPHGDSA-LNEQEK 145
Score = 32.7 bits (73), Expect = 1.1
Identities = 28/85 (32%), Positives = 29/85 (34%), Gaps = 24/85 (28%)
Query: 53 PVPP------QPPQPPPGPASASGPGAAG------PASSPPPAGPGPGPALPAVRLSLVR 100
P PP P P G A G GAA P PPPA P P P
Sbjct: 36 PAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPP------- 88
Query: 101 LGEPDSAGAGEP---PATPAGLGSG 122
P A A P P P GL +G
Sbjct: 89 --PPPPASAAAPASGPPAPPGLAAG 111
Score = 30.4 bits (67), Expect = 5.6
Identities = 25/82 (30%), Positives = 27/82 (32%), Gaps = 20/82 (24%)
Query: 55 PPQPPQ----------PPPG----------PASASGPGAAGPASSPPPAGPGPGPALPAV 94
PP PPQ PPP PA + + PA SP G G A
Sbjct: 6 PPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAA 65
Query: 95 RLSLVRLGEPDSAGAGEPPATP 116
L L P A A PP P
Sbjct: 66 ALLLHPPPPPPPATAAPPPPPP 87
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 50.1 bits (118), Expect = 7e-06
Identities = 36/90 (40%), Positives = 39/90 (43%), Gaps = 11/90 (12%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG------PGPGPA 90
P A R PA+A PP P PPP PA + AA PA +P A P PGPA
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVA---AAAPARAPRAAAAAATAPPSPGPA 165
Query: 91 LPAVRLS-LVRLGEPDSAGAGEPP-ATPAG 118
P R L P A A P A PAG
Sbjct: 166 QPGPRAQRAAPLAAPPPAPAAPPAVAPPAG 195
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/82 (36%), Positives = 36/82 (43%), Gaps = 15/82 (18%)
Query: 42 ARRSGPASAQTPVPPQPPQPPP-----GPASASGPGAAGPASSPPPAGP--GPGPALPAV 94
A R+ A+A P P P QP P P +A P A P + PPAGP P PA+ A
Sbjct: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAA- 206
Query: 95 RLSLVRLGEPDSAGAGEPPATP 116
EP +PPA P
Sbjct: 207 -------REPPLPPPPQPPAPP 221
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/106 (32%), Positives = 43/106 (40%), Gaps = 7/106 (6%)
Query: 27 RTREGFYKLLPGDGAARRS--GPASAQTPVPPQPPQ----PPPGPASASGPGAAGPASSP 80
RTR KL+ R S G S + QPP+ PP P + G AA A++P
Sbjct: 68 RTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAP 127
Query: 81 PPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT-PAGLGSGGDR 125
PP P P P + R +A A PP+ PA G R
Sbjct: 128 PPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQR 173
Score = 39.3 bits (90), Expect = 0.012
Identities = 25/75 (33%), Positives = 30/75 (40%), Gaps = 7/75 (9%)
Query: 42 ARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRL 101
AR A+A PP P PGP + A P ++PPPA P P R
Sbjct: 146 ARAPRAAAAAATAPPSPGPAQPGPRAQ----RAAPLAAPPPAPAAPPAVAPPAG---PRR 198
Query: 102 GEPDSAGAGEPPATP 116
P + A EPP P
Sbjct: 199 APPPAVAAREPPLPP 213
Score = 33.9 bits (76), Expect = 0.50
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALP 92
P G A+ GP + + PP P P + + P AGP +PPPA P LP
Sbjct: 160 PSPGPAQ-PGPRAQRAAPLAAPPPAPAAPPAVAPP--AGPRRAPPPAVAAREPPLP 212
Score = 33.1 bits (74), Expect = 0.86
Identities = 27/76 (35%), Positives = 28/76 (36%), Gaps = 6/76 (7%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAG---PGPGPALPA 93
P G R PA A P PP PP P P P PPP G G A P
Sbjct: 192 PPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQP--PPPQPQPPPEGGAVRAGGAARPV 249
Query: 94 VRLSLVR-LGEPDSAG 108
+VR LG AG
Sbjct: 250 SLREVVRYLGGSGGAG 265
Score = 31.2 bits (69), Expect = 3.3
Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 9/64 (14%)
Query: 41 AARRSGPASAQTPVPPQPPQPPPGPASAS---------GPGAAGPASSPPPAGPGPGPAL 91
AA PA+ PP P+ P PA A+ P A PPP P P P
Sbjct: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEG 237
Query: 92 PAVR 95
AVR
Sbjct: 238 GAVR 241
>gi|134142824 forkhead box D2 [Homo sapiens]
Length = 495
Score = 49.7 bits (117), Expect = 9e-06
Identities = 37/85 (43%), Positives = 45/85 (52%), Gaps = 7/85 (8%)
Query: 42 ARRSGPASAQTPVPP-QPPQPPPGPASASGPGAAGPASSPPPA---GPGPGPA-LPAVRL 96
A + A Q VPP + PPPGP +AS AG A +P PA GPGPGPA LPA
Sbjct: 298 AAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAFLG 357
Query: 97 SLVRLGEPDSAGAGEPPA--TPAGL 119
+ + + A + PPA T AGL
Sbjct: 358 AELGCAKAFYAASLSPPAAGTAAGL 382
Score = 35.8 bits (81), Expect = 0.13
Identities = 45/172 (26%), Positives = 55/172 (31%), Gaps = 19/172 (11%)
Query: 407 AAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTP 466
A G G AP P P + + +A Q + P PP A G
Sbjct: 276 AYGAPPPGPAP-HPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASV--FAGAG 332
Query: 467 GTTPPAASSSRGGEPGPGPLPRSLSR---------SNSLPHPAGGGKAGGPGVAAEPGTP 517
PA +S G PGP LP L + SL PA G AG P G
Sbjct: 333 SAPAPAPASGSGPGPGPAGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLK 392
Query: 518 FSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569
G A GA + S+ +I G GG+ G P P
Sbjct: 393 TDAGGGA-------GGGGAGAGQRPSFSIDHIMGHGGGGAAPPGAGEGSPGP 437
Score = 34.7 bits (78), Expect = 0.30
Identities = 34/121 (28%), Positives = 41/121 (33%), Gaps = 38/121 (31%)
Query: 39 DGAARRSGPASAQTPVPPQPPQPPPGP--------ASASGPGA----------------- 73
+G+ R + P+PP P P P P A+A PGA
Sbjct: 213 NGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGL 272
Query: 74 AGPASSPPPAGPGPGP--------ALPAVRLSLVRLGEPDSAGAGEPPATP-----AGLG 120
A PA PP GP P P A + +L P A PP P AG G
Sbjct: 273 ALPAYGAPPPGPAPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAG 332
Query: 121 S 121
S
Sbjct: 333 S 333
Score = 33.9 bits (76), Expect = 0.50
Identities = 35/121 (28%), Positives = 41/121 (33%), Gaps = 23/121 (19%)
Query: 4 GGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPP 63
GGA PGA + A + G+ LP GA P P P P P
Sbjct: 245 GGAAAAGDPGAFLPGFAAYGAY---GYGYGLALPAYGAP---------PPGPAPHPHPHP 292
Query: 64 GPASASGPGAAGPA--SSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGS 121
+ + AA P S PP P P P + AGAG PA GS
Sbjct: 293 HAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASV---------FAGAGSAPAPAPASGS 343
Query: 122 G 122
G
Sbjct: 344 G 344
Score = 31.2 bits (69), Expect = 3.3
Identities = 12/22 (54%), Positives = 14/22 (63%)
Query: 63 PGPASASGPGAAGPASSPPPAG 84
PGP +A+ GAAGP PP G
Sbjct: 97 PGPGAAAARGAAGPGPGPPSGG 118
Score = 30.0 bits (66), Expect = 7.3
Identities = 13/26 (50%), Positives = 17/26 (65%)
Query: 64 GPASASGPGAAGPASSPPPAGPGPGP 89
G A+A+G G A++ AGPGPGP
Sbjct: 89 GAAAAAGSPGPGAAAARGAAGPGPGP 114
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 49.7 bits (117), Expect = 9e-06
Identities = 38/117 (32%), Positives = 50/117 (42%), Gaps = 15/117 (12%)
Query: 20 AEIKSQFRTREGFYKLLPGDGAARRSGPASAQTP----VPPQPPQPPPGPASASGPGAAG 75
AE +SQ + +E + ++++ P + P PP P PP GP A G
Sbjct: 366 AEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPG 425
Query: 76 PASSPPPAGPGPG-------PALPAVRLSLVRL---GEPDSAGAGEPPATPAGLGSG 122
P + PP GP PG P +P +R L RL G P G PP P GL G
Sbjct: 426 PPTGLPP-GPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPG 481
Score = 40.8 bits (94), Expect = 0.004
Identities = 27/68 (39%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 53 PVPPQPPQPPPGPASASGPGA---AGPASSPPPAGPGPGPALPA-VRLSLVRLGEPDSAG 108
P P +PP PPPGP PG P PPPA PG P P +R LV P G
Sbjct: 462 PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPG 521
Query: 109 AGEPPATP 116
P P
Sbjct: 522 LFPPAPLP 529
Score = 34.3 bits (77), Expect = 0.39
Identities = 24/66 (36%), Positives = 27/66 (40%), Gaps = 4/66 (6%)
Query: 37 PGDGAARRSGPASAQTPVPPQPPQ-PPPGPASASGPGAAGPASSPPPAGPGPG-PALPAV 94
PG R P PP P PPPGP PG P PPP P P P +P
Sbjct: 445 PGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGP--PPRGPPPRLPPPAPPGIPPP 502
Query: 95 RLSLVR 100
R ++R
Sbjct: 503 RPGMMR 508
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/65 (35%), Positives = 25/65 (38%), Gaps = 5/65 (7%)
Query: 64 GPASASGPGAAGPASSPP-----PAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAG 118
G ++AS A P S PP P PGP P P L G P G PP P
Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPF 441
Query: 119 LGSGG 123
L G
Sbjct: 442 LRPPG 446
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 49.7 bits (117), Expect = 9e-06
Identities = 31/120 (25%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
Query: 274 RNPLAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVC 333
R +++ P+ FS DG+ LA S+D ++V+ + + + C
Sbjct: 92 RGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVRCAK 151
Query: 334 WSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGAD 393
+SPDGR +V+ ED + +W T + V + N V F+P T +AG+D
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGT----CIASAGSD 207
Score = 48.1 bits (113), Expect = 3e-05
Identities = 27/87 (31%), Positives = 41/87 (47%)
Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVT 351
FSP G LA S+D +R++ D K++ + V +S DG+++ T ED +
Sbjct: 68 FSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIK 127
Query: 352 VWSFTEGRVVARGHGHKSWVNAVAFDP 378
VWS R + + H WV F P
Sbjct: 128 VWSMYRQRFLYSLYRHTHWVRCAKFSP 154
Score = 48.1 bits (113), Expect = 3e-05
Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 8/161 (4%)
Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVT 351
FSPDGR + S+D ++++ + G V ++P G + + G D V
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVK 211
Query: 352 VWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGE-RSGEEEEEEPEAAGT 410
VW +++ H VN ++F P + A +DG + + E
Sbjct: 212 VWDVRVNKLLQHYQVHSGGVNCISFHP----SGNYLITASSDGTLKILDLLEGRLIYTLQ 267
Query: 411 GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLY 451
G G K G + F S G DTQ LW D L+
Sbjct: 268 GHTGPVFTVSFSKGGEL---FASGGADTQVLLWRTNFDELH 305
Score = 47.4 bits (111), Expect = 4e-05
Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 4/109 (3%)
Query: 285 GPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTG 344
G N F+P G +A D ++V+ L + + GG+ C+ + P G Y++T
Sbjct: 187 GFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITA 246
Query: 345 GEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGAD 393
D + + EGR++ GH V V+F ++ E + GAD
Sbjct: 247 SSDGTLKILDLLEGRLIYTLQGHTGPVFTVSF----SKGGELFASGGAD 291
Score = 40.4 bits (93), Expect = 0.005
Identities = 22/77 (28%), Positives = 35/77 (45%)
Query: 277 LAKWAVGEGPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSP 336
L + V G +N +F P G +L S DG L++ L ++ + G + V +S
Sbjct: 221 LQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSFSK 280
Query: 337 DGRYVVTGGEDDLVTVW 353
G +GG D V +W
Sbjct: 281 GGELFASGGADTQVLLW 297
Score = 33.9 bits (76), Expect = 0.50
Identities = 17/63 (26%), Positives = 29/63 (46%)
Query: 317 LLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAF 376
+L K + + + SP+G+ + T D + +W+F R GHK V +V F
Sbjct: 9 VLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQF 68
Query: 377 DPY 379
P+
Sbjct: 69 SPH 71
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 49.3 bits (116), Expect = 1e-05
Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 4/115 (3%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPVPPQPPQPPP 63
G+ G GP GD E + ++ PG+ GA GPA Q + P P
Sbjct: 1080 GSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR 1139
Query: 64 GPASASG-PGAAGPASSPPPAGPGPGP-ALPAVRLSLVRLGEPDSAGAGEPPATP 116
GP SG PG G + P P GP PGP R S G P G PP P
Sbjct: 1140 GPVGPSGPPGKDGTSGHPGPIGP-PGPRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193
Score = 47.8 bits (112), Expect = 3e-05
Identities = 40/127 (31%), Positives = 48/127 (37%), Gaps = 12/127 (9%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG-PASAQTPVPPQPPQPPP 63
G+ G GP C + + Y + G +G P A P PP PP
Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG 189
Query: 64 GPASASGPGAAGPASSPPPAGP-GP-------GPALPAVR-LSLVRLGEPDSAGAGEPPA 114
P S PG GP P AGP GP GP+ PA + R G P G PP
Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG 249
Query: 115 T--PAGL 119
PAG+
Sbjct: 250 IKGPAGI 256
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/122 (34%), Positives = 48/122 (39%), Gaps = 16/122 (13%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
G GGSGP G +K + R G G GAA P + P PP P
Sbjct: 843 GPPGGSGPAGPPGPQG-VKGE-RGSPG------GPGAA--GFPGARGLPGPPGSNGNPGP 892
Query: 65 PASASGPGAAGPASSPPPAGPGPGPALPAV---RLSLVRLGEPDSAGAGEPPATPAGLGS 121
P + PG GP P PAG P P V + + GE S GA PP P LG
Sbjct: 893 PGPSGSPGKDGP---PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949
Query: 122 GG 123
G
Sbjct: 950 AG 951
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/154 (30%), Positives = 51/154 (33%), Gaps = 47/154 (30%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPA--SAQTPVPPQPPQPP 62
GA G GP A G+ R R G LPG AR + A S P PP PP
Sbjct: 294 GAPGPMGPRGAPGE--------RGRPG----LPGAAGARGNDGARGSDGQPGPPGPPGTA 341
Query: 63 PGPASASGPGAAGPASSP----------------------PPAGPG----------PGPA 90
P S G GPA SP PP PG GPA
Sbjct: 342 GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA 401
Query: 91 -LPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
+P + G P AGA P G G G
Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435
Score = 40.8 bits (94), Expect = 0.004
Identities = 58/200 (29%), Positives = 67/200 (33%), Gaps = 31/200 (15%)
Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSP-LPKAGSITYRFGSAGQDTQFCLWDLTE 447
A G GE E P G A G P LP A G+ G D Q
Sbjct: 280 APGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQ-------- 331
Query: 448 DVLYPHPP-LARTRTLPGTPGT---TPPAASSSRGGEPGP--GPLPRSLSRSNSLPHPAG 501
P PP T PG+PG PA S G PG P P+ + + P P G
Sbjct: 332 ----PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387
Query: 502 -GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSG 560
G GG G G P + G RG + G RGG+G G
Sbjct: 388 INGSPGGKGEMGPAGIPGAPGLMGA--------RGPPGPAGANGAPG--LRGGAGEPGKN 437
Query: 561 GEKPSGPVPRSRLDPAKVLG 580
G K P PR A + G
Sbjct: 438 GAK-GEPGPRGERGEAGIPG 456
Score = 40.8 bits (94), Expect = 0.004
Identities = 38/134 (28%), Positives = 49/134 (36%), Gaps = 27/134 (20%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGF-----YKLLPGD----GAARRSGPASAQ---- 51
GA G +GP A G+ R+G + +PG G+ + GP +Q
Sbjct: 510 GAPGPAGPRGAAGEPG--------RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESG 561
Query: 52 TPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111
P PP P P P PG G +P G GP P + G P G
Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ------GPPGKNGETG 615
Query: 112 PPATPAGLGSGGDR 125
P P G GGD+
Sbjct: 616 PQGPPGPTGPGGDK 629
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 17/121 (14%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP-PP 63
G G +GPG GD Q + LPG G GP +P +P P
Sbjct: 618 GPPGPTGPGGDKGDTGPPGPQG------LQGLPGTG-----GPPGENG----KPGEPGPK 662
Query: 64 GPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122
G A A G PG G A +P GP P +R G GA PP P G+
Sbjct: 663 GDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTP 722
Query: 123 G 123
G
Sbjct: 723 G 723
Score = 40.4 bits (93), Expect = 0.005
Identities = 31/95 (32%), Positives = 34/95 (35%), Gaps = 10/95 (10%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGP-------ASASGPGAAGPASS---PPPAGPGPGP 89
G GP P P PPGP S GPGAAG + P P G P
Sbjct: 831 GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890
Query: 90 ALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGGD 124
P S + G P AG P +P G GD
Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD 925
Score = 39.7 bits (91), Expect = 0.009
Identities = 32/91 (35%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 38 GDGAARRSG-PASAQTPVPPQPPQPPPGPASASGP----GAAGPASSPPPAGPGPGPALP 92
G G +G P + P P PP P GPA SG G AGPA +P PAG P
Sbjct: 1030 GKGDRGENGSPGAPGAPGHPGPPGPV-GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ 1088
Query: 93 AVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
R GE +AG P G+ G
Sbjct: 1089 GPRGDKGETGERGAAGIKGHRGFPGNPGAPG 1119
Score = 39.3 bits (90), Expect = 0.012
Identities = 45/146 (30%), Positives = 53/146 (36%), Gaps = 24/146 (16%)
Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448
A G +GE G+ E P G GG P P GS G AG + +
Sbjct: 814 APGQNGEPGGKGERGAP---GEKGEGGPPGVAGPPGGS-----GPAGPPGP---QGVKGE 862
Query: 449 VLYPHPPLAR----TRTLPGTPGTT----PPAASSSRGGEPGPGP-----LPRSLSRSNS 495
P P A R LPG PG+ PP S S G + PGP P S S
Sbjct: 863 RGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922
Query: 496 LPHPAGGGKAGGPGVAAEPGTPFSIG 521
G+ G PG PG P +G
Sbjct: 923 KGDAGQPGEKGSPGAQGPPGAPGPLG 948
Score = 38.9 bits (89), Expect = 0.016
Identities = 57/204 (27%), Positives = 67/204 (32%), Gaps = 51/204 (25%)
Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445
A A G G+ E P AG G P P+ G G+AG
Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK-----GAAGP--------- 712
Query: 446 TEDVLYPHPP-LARTRTLPGTPGTT----PPAASSSRGGEPGPGPL-------PRSLSRS 493
P PP A T L G PG P +G GPG PR +
Sbjct: 713 ------PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGP 766
Query: 494 NSLPHPAG-------GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSL 546
P PAG GG G PG+A G+P ER + G +
Sbjct: 767 IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP-----------GERGETGPPGPAGFPGAP 815
Query: 547 G-NISRGGSGGSGSGGEKPSGPVP 569
G N GG G G+ GEK G P
Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPP 839
Score = 38.9 bits (89), Expect = 0.016
Identities = 34/121 (28%), Positives = 40/121 (33%), Gaps = 9/121 (7%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
GA G GP A G ++ R G P GP + P G
Sbjct: 708 GAAGPPGPPGAAGTPG-LQGMPGERGGLGSPGPKGDKGEPGGPGADGVP-------GKDG 759
Query: 65 PASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P +GP G GPA P G G P LP + GE G P P G G
Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819
Query: 124 D 124
+
Sbjct: 820 E 820
Score = 38.9 bits (89), Expect = 0.016
Identities = 32/119 (26%), Positives = 38/119 (31%), Gaps = 1/119 (0%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
G +G GP +G EG LPG A R P PP P P
Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI-AGPRGSPGERGETGPPGPAGFPGA 814
Query: 65 PASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P PG G +P G G P + G P G +P G G+ G
Sbjct: 815 PGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG 873
Score = 38.9 bits (89), Expect = 0.016
Identities = 44/147 (29%), Positives = 56/147 (38%), Gaps = 40/147 (27%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP 62
A GA G GP +G KS R G G A GPA ++ PQ P+
Sbjct: 1042 APGAPGHPGPPGPVGPAG--KSGDRGESG------PAGPAGAPGPAGSRGAPGPQGPRGD 1093
Query: 63 PG----------------PASASGPGAAGPA------SSPPPAGP-GP-GPALPAVRLSL 98
G P + PG+ GPA SP PAGP GP GP+ P
Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP----- 1148
Query: 99 VRLGEPDSAGAGEPPATPAGLGSGGDR 125
G+ ++G P P G+ G+R
Sbjct: 1149 ---GKDGTSGHPGPIGPPGPRGNRGER 1172
Score = 38.5 bits (88), Expect = 0.020
Identities = 52/203 (25%), Positives = 66/203 (32%), Gaps = 35/203 (17%)
Query: 387 ATAAGADGERSGEEEEEEPEAAGT----GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCL 442
A A GA G R G E + A G G G A + +P A + GS G+ L
Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGL 478
Query: 443 WDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG 502
P A R PG G P G G P + P
Sbjct: 479 -----------PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527
Query: 503 GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNIS------------ 550
G GGPG+ PG+P G + G++ E R G
Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDG-----KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582
Query: 551 -RGGSGGSGSGGEK--PSGPVPR 570
+G G G GE+ P GP P+
Sbjct: 583 PKGNDGAPGKNGERGGPGGPGPQ 605
Score = 38.1 bits (87), Expect = 0.027
Identities = 39/140 (27%), Positives = 46/140 (32%), Gaps = 35/140 (25%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-GAARRSGPASAQTPV--------- 54
GA G G GD + PG+ G+ GP A P+
Sbjct: 912 GAPGSPGVSGPKGDAGQ---------------PGEKGSPGAQGPPGAPGPLGIAGITGAR 956
Query: 55 ----PPQPPQP--PPGPASASG----PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEP 104
PP P P PGP G PGA G + P GP P L R G P
Sbjct: 957 GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP 1016
Query: 105 DSAGAGEPPATPAGLGSGGD 124
S G +P G G G+
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGE 1036
Score = 37.4 bits (85), Expect = 0.046
Identities = 27/90 (30%), Positives = 27/90 (30%), Gaps = 13/90 (14%)
Query: 38 GDGAARRSGPASAQTPVPPQPPQPPPGPASASG----PGAAGPASSPPPAGPGPGPALPA 93
G G GP PQ P P GP G PG G P GP P
Sbjct: 598 GPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP- 656
Query: 94 VRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
GEP G P P G G G
Sbjct: 657 --------GEPGPKGDAGAPGAPGGKGDAG 678
Score = 37.0 bits (84), Expect = 0.059
Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 30/118 (25%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPG 509
P PP A TR PP +G G+PGP +P G+ G PG
Sbjct: 89 PQPPTAPTR---------PPNGQGPQGPKGDPGPPGIP---------------GRNGDPG 124
Query: 510 VAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567
+ +PG+P S G + E G + +Y S ++ G + G +G P+GP
Sbjct: 125 IPGQPGSPGSPG---PPGICESCPTGPQNYSPQYDSY-DVKSGVAVGGLAGYPGPAGP 178
Score = 36.6 bits (83), Expect = 0.078
Identities = 53/203 (26%), Positives = 71/203 (34%), Gaps = 43/203 (21%)
Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAP-----LSPLPKAGSITYRFGSAGQDTQF 440
AA A G DG R + + P GT G+P + P GS G+ GQ +
Sbjct: 316 AAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS----NGAPGQRGE- 370
Query: 441 CLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPH 498
P G PG PP + S G GE GP +P + +
Sbjct: 371 -------------PGPQGHAGAQGPPG--PPGINGSPGGKGEMGPAGIPGAPGLMGARGP 415
Query: 499 PAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDR-------GAEKEHKRYHSLGNISR 551
P G G PG+ G P G + R GA+ E + S G
Sbjct: 416 PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPG--EP 473
Query: 552 GGSGGSGSGGEK-------PSGP 567
G +G G+ GE+ P+GP
Sbjct: 474 GANGLPGAAGERGAPGFRGPAGP 496
Score = 36.2 bits (82), Expect = 0.10
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 6/54 (11%)
Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515
L G PGT P + + GEPGP + + P G G AG PG PG
Sbjct: 640 LQGLPGTGGPPGENGKPGEPGPK------GDAGAPGAPGGKGDAGAPGERGPPG 687
Score = 35.4 bits (80), Expect = 0.17
Identities = 24/63 (38%), Positives = 28/63 (44%), Gaps = 14/63 (22%)
Query: 54 VPPQPPQPPPGPASASGPGAAGPASSP-PPAGPGPG--PALPAVRLSLVRLGEPDSAGAG 110
V PQPP P P + GP GP P PP PG P +P G+P S G+
Sbjct: 87 VCPQPPTAPTRPPNGQGP--QGPKGDPGPPGIPGRNGDPGIP---------GQPGSPGSP 135
Query: 111 EPP 113
PP
Sbjct: 136 GPP 138
Score = 35.4 bits (80), Expect = 0.17
Identities = 36/127 (28%), Positives = 43/127 (33%), Gaps = 8/127 (6%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD-------GAARRSGPASAQTPVPPQ 57
GA+G GP G+ E PG+ GAA G + P P
Sbjct: 438 GAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497
Query: 58 PPQPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATP 116
GPA G PG AGP + G P P +R G P S G PP +
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557
Query: 117 AGLGSGG 123
G G
Sbjct: 558 GESGRPG 564
Score = 35.0 bits (79), Expect = 0.23
Identities = 37/125 (29%), Positives = 44/125 (35%), Gaps = 13/125 (10%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVL 450
G+ G + + E P A G G P P G G AGQ D E
Sbjct: 735 GSPGPKGDKGEPGGPGADGVPGKDG-PRGPTGPIGPP----GPAGQPG-----DKGEGGA 784
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
P +A R PG G T P + G PG P + P G+ G PGV
Sbjct: 785 PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGA---PGEKGEGGPPGV 841
Query: 511 AAEPG 515
A PG
Sbjct: 842 AGPPG 846
Score = 35.0 bits (79), Expect = 0.23
Identities = 34/109 (31%), Positives = 38/109 (34%), Gaps = 10/109 (9%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PG P + G PGP P + P G G PG E G P G F
Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAG-F 811
Query: 524 ATLTLQE-----RRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGP 567
Q + +RGA E G G GGSG G P GP
Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPG--VAGPPGGSGPAG--PPGP 856
Score = 35.0 bits (79), Expect = 0.23
Identities = 52/184 (28%), Positives = 60/184 (32%), Gaps = 35/184 (19%)
Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTED 448
A G GER + P AGT G +P + + R GS G D E+
Sbjct: 985 ANGLSGERGPPGPQGLPGLAGTAGEPGRDGNP--GSDGLPGRDGSPGGKG-----DRGEN 1037
Query: 449 VLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGP 508
P P A PG PG PA S GE GP G AG P
Sbjct: 1038 GS-PGAPGAPGH--PGPPGPVGPAGKSGDRGESGP------------------AGPAGAP 1076
Query: 509 GVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGS-----GGEK 563
G A G P G R K H+ + GN GS G G
Sbjct: 1077 GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP--GNPGAPGSPGPAGQQGAIGSPG 1134
Query: 564 PSGP 567
P+GP
Sbjct: 1135 PAGP 1138
Score = 34.7 bits (78), Expect = 0.30
Identities = 36/120 (30%), Positives = 47/120 (39%), Gaps = 18/120 (15%)
Query: 415 GAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDV----LYPHPPLARTRTLPGTPGTT- 469
G+P SP P + G Q+ +D+ V L +P A PG PGT+
Sbjct: 130 GSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSG 189
Query: 470 PPAASSSRG-----GEPG-------PGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
P + S G GEPG PGP P ++ S G+ G PG PG P
Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPSGPAGKDGESGRPGRPGERGLPGPP 248
Score = 34.7 bits (78), Expect = 0.30
Identities = 34/118 (28%), Positives = 40/118 (33%), Gaps = 10/118 (8%)
Query: 463 PGTPGTTPPAASSSRGGEPGP-GPL-PRSLSRSNSLPHPAGG-------GKAGGPGVAAE 513
PG+ G P S G PGP GP PR P P G G+ GGPG
Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604
Query: 514 PGTPFSIGRFATLTLQERRDRGAEK-EHKRYHSLGNISRGGSGGSGSGGEKPSGPVPR 570
G P G G +K + G G+GG KP P P+
Sbjct: 605 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662
Score = 34.3 bits (77), Expect = 0.39
Identities = 34/130 (26%), Positives = 45/130 (34%), Gaps = 17/130 (13%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAP----LSPLPKAGSITYRFGSAGQDTQFCLWDLT 446
G GE+ E P AG A G P + P + G G D +
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK------- 550
Query: 447 EDVLYPHPPLARTRT-LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKA 505
P PP ++ + PG PG + P G PGP + ++ P G G
Sbjct: 551 -----PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605
Query: 506 GGPGVAAEPG 515
G PG E G
Sbjct: 606 GPPGKNGETG 615
Score = 33.5 bits (75), Expect = 0.66
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 8/61 (13%)
Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122
PGPA G GP P +G P P + GEP AG PP P +G
Sbjct: 173 PGPA-----GPPGPPGPPGTSGHPGSPGSPGYQ---GPPGEPGQAGPSGPPGPPGAIGPS 224
Query: 123 G 123
G
Sbjct: 225 G 225
Score = 33.5 bits (75), Expect = 0.66
Identities = 36/113 (31%), Positives = 37/113 (32%), Gaps = 13/113 (11%)
Query: 457 ARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGT 516
A R PG G A R G PG GP R + S P GK G PG E G
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPG-GPGMRGMPGSPG--GPGSDGKPGPPGSQGESGR 562
Query: 517 PFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGG--SGSGGEKPSGP 567
P G RG GN G G G GG P GP
Sbjct: 563 PGPPG--------PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP 607
Score = 33.5 bits (75), Expect = 0.66
Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 18/73 (24%)
Query: 463 PGTPGTTPPAASSSRGGEPGP----GPL----PRSLSRSNSLPHPAGG----------GK 504
PG PG+ PA G PGP GP+ P ++ P P G G
Sbjct: 1115 PGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGS 1174
Query: 505 AGGPGVAAEPGTP 517
G PG +PG P
Sbjct: 1175 EGSPGHPGQPGPP 1187
Score = 32.0 bits (71), Expect = 1.9
Identities = 58/224 (25%), Positives = 71/224 (31%), Gaps = 47/224 (20%)
Query: 378 PYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQD 437
P + A+ AG+ G + EP G A G P P I G G
Sbjct: 344 PGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP-----GINGSPGGKG-- 396
Query: 438 TQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPG-----PLPRSLSR 492
++ + P L R PG G GEPG P PR
Sbjct: 397 ------EMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450
Query: 493 SNSLPHPAGG----GKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGN 548
+P G GK G PG G P + G +RGA
Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAG-----------ERGAPG---------- 489
Query: 549 ISRGGSGGSGSGGEK-PSGPVPRSRLDPAKVLGTALCPRIHEVP 591
RG +G +G GEK P+G R PA G A P VP
Sbjct: 490 -FRGPAGPNGIPGEKGPAG--ERGAPGPAGPRGAAGEPGRDGVP 530
Score = 32.0 bits (71), Expect = 1.9
Identities = 49/187 (26%), Positives = 61/187 (32%), Gaps = 51/187 (27%)
Query: 389 AAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKA-GSITYRFGSAGQDTQFCLWDLTE 447
A G+ G + + +P G+ A G P +P P IT G AG
Sbjct: 913 APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGP----------- 961
Query: 448 DVLYPHPPLARTRTLPGTPGTT----PPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAG 501
P + R PG G P A+ G G PGP LP + + P
Sbjct: 962 ------PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP---GLAGTAGEPGR 1012
Query: 502 GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGG 561
G G G+ G+P G DRG N S G G G G
Sbjct: 1013 DGNPGSDGLPGRDGSPGGKG-----------DRGE-----------NGSPGAPGAPGHPG 1050
Query: 562 EKPSGPV 568
P GPV
Sbjct: 1051 --PPGPV 1055
Score = 31.6 bits (70), Expect = 2.5
Identities = 35/117 (29%), Positives = 42/117 (35%), Gaps = 31/117 (26%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASG-PGAAGPASSPPPAG----PGPG------ 88
G GPA + PPGPA A+G PG G A P G PGP
Sbjct: 393 GGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA 452
Query: 89 --PALPAVRLSLVRLGEPDSAGA----------GEP----PATPAGL----GSGGDR 125
P +P + + G P GA G P PA P G+ G G+R
Sbjct: 453 GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER 509
Score = 31.6 bits (70), Expect = 2.5
Identities = 23/62 (37%), Positives = 24/62 (38%), Gaps = 5/62 (8%)
Query: 62 PPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGS 121
PPGP G GAAGP P P G P L + LG P G P P G
Sbjct: 700 PPGPEG--GKGAAGP---PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV 754
Query: 122 GG 123
G
Sbjct: 755 PG 756
Score = 30.0 bits (66), Expect = 7.3
Identities = 28/95 (29%), Positives = 31/95 (32%), Gaps = 18/95 (18%)
Query: 47 PASAQTPVPPQPPQPPPG-PASASGPGAAGPASSPPPAGP---------GPGPALPAVRL 96
P + Q P P+ PPG P PG G SP GP GP P
Sbjct: 98 PPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDS 157
Query: 97 SLVR--------LGEPDSAGAGEPPATPAGLGSGG 123
V+ G P AG PP P G G
Sbjct: 158 YDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPG 192
Score = 30.0 bits (66), Expect = 7.3
Identities = 24/74 (32%), Positives = 26/74 (35%), Gaps = 10/74 (13%)
Query: 454 PPLARTRTLP-GTPGTTPPAASSSRGGEPGPGPL--------PRSLSRSNSLPHPAG-GG 503
PP T P G PG T P G PGP L P + P P G G
Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666
Query: 504 KAGGPGVAAEPGTP 517
G PG + G P
Sbjct: 667 APGAPGGKGDAGAP 680
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/90 (30%), Positives = 48/90 (53%), Gaps = 6/90 (6%)
Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFG---GLLCVCWSPDGRYVVTGGEDD 348
F P G +A SQD ++++ + +G + Y G + C+ +SPDG+++ + +D
Sbjct: 113 FHPYGEFVASGSQDTNIKLW---DIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDH 169
Query: 349 LVTVWSFTEGRVVARGHGHKSWVNAVAFDP 378
V +W T G++++ GH VN V F P
Sbjct: 170 TVKLWDLTAGKMMSEFPGHTGPVNVVEFHP 199
Score = 38.5 bits (88), Expect = 0.020
Identities = 18/76 (23%), Positives = 34/76 (44%)
Query: 303 SQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVA 362
SQ G +RV+ ++ + + + + + + P G +V +G +D + +W V
Sbjct: 82 SQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVF 141
Query: 363 RGHGHKSWVNAVAFDP 378
R GH V + F P
Sbjct: 142 RYRGHSQAVRCLRFSP 157
Score = 37.7 bits (86), Expect = 0.035
Identities = 21/87 (24%), Positives = 41/87 (47%)
Query: 292 FSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVT 351
FSPDG+ LA + D ++++ + + + G + V + P+ + +G D +
Sbjct: 155 FSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
Query: 352 VWSFTEGRVVARGHGHKSWVNAVAFDP 378
W + +VV+ G V +V F+P
Sbjct: 215 FWDLEKFQVVSCIEGEPGPVRSVLFNP 241
Score = 31.6 bits (70), Expect = 2.5
Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 18/114 (15%)
Query: 338 GRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERS 397
GR + TGG+D V +WS + + GH S V +V + EE A G +S
Sbjct: 33 GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLN----TPEELIVA----GSQS 84
Query: 398 GEEEEEEPEAAGT------GSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445
G + EAA A L P + S QDT LWD+
Sbjct: 85 GSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFV----ASGSQDTNIKLWDI 134
Score = 31.2 bits (69), Expect = 3.3
Identities = 18/65 (27%), Positives = 32/65 (49%)
Query: 285 GPLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTG 344
GP+N F P+ LA S D +R + + + ++ G + V ++PDG + +G
Sbjct: 190 GPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
Query: 345 GEDDL 349
+D L
Sbjct: 250 CQDSL 254
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 48.9 bits (115), Expect = 2e-05
Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62
G+ G +GP G + + + +G G A G S TPVP P PP PP
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664
Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119
PGP G PG+ G P GP P +P + G P G P T L
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720
Query: 120 GSGG 123
G G
Sbjct: 721 GCPG 724
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%)
Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84
K LPG G SG Q P P P P PGPA +GP GP P P
Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635
Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124
PG PG A P LS+ G P G PP P LG GD
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511
P + +LPG+PG PP G GEPGP P +L P GK G PG A
Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405
Query: 512 AEPGTPFSIG 521
E G S G
Sbjct: 1406 GEKGNKGSKG 1415
Score = 39.3 bits (90), Expect = 0.012
Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505
+P PP +PG G P S G PGP P S S+ HP G
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279
Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564
G PG A + G P +G T L R D G + GN GS G G P
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338
Query: 565 SGPVPRSRLDP 575
GP P R DP
Sbjct: 1339 KGP-PGVRGDP 1348
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%)
Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504
PG+PG PA G GEPG PGP PR LS S +P P G G
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663
Query: 505 AGGPGVAAEPGTPFSIGR 522
G PG PG P S+G+
Sbjct: 664 PGHPGPQGPPGIPGSLGK 681
Score = 37.0 bits (84), Expect = 0.059
Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56
G +G G MG+ IK Q FR +Y G GP + P
Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370
Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112
Q P PPG P S PG++ P P PG G R +G P S G AG P
Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427
Query: 113 -PATPAGLGSGGDRV 126
P +P G GD V
Sbjct: 428 LPGSPGPPGPPGDIV 442
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47
A G +G SGP G + R G+ L G R G P
Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426
Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88
+P PP PP + PPG G PG GP P P PGP
Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486
Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P LP + G +AG P +P G G
Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523
Score = 35.0 bits (79), Expect = 0.23
Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522
PG PG PA G PG LP L G G PG+ PG P G
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147
Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569
+ ++ + R EK RG G G+ G++ + P
Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200
Score = 34.3 bits (77), Expect = 0.39
Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%)
Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61
A G G G A GD R GF L GA +GP P +
Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225
Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPG A PG G P S P PG PG + ++ +G P G PP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282
Query: 114 ATPAGLGSGG 123
T +G G
Sbjct: 1283 GTAGDMGPPG 1292
Score = 33.9 bits (76), Expect = 0.50
Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%)
Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95
R P + P P P Q PG G PG G P P GP GP P VR
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349
Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125
L ++ L GEP G PP P LG G R
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390
Score = 33.5 bits (75), Expect = 0.66
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118
PGP + G G GP P P GP P LP + S VR G P +G+ P TP
Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113
Query: 119 LGSGG 123
G G
Sbjct: 114 TGPYG 118
Score = 33.5 bits (75), Expect = 0.66
Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%)
Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457
G + EP GT GAP P G AG P L+
Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649
Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
+ +PG PG P G GP +P SL + P G+ G PG+ PG P
Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705
Score = 33.1 bits (74), Expect = 0.86
Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%)
Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
P L + LPG G P S+ GEPG +P S+ G G PG
Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 511 AAEPGTP 517
A PG P
Sbjct: 1038 AGRPGLP 1044
Score = 33.1 bits (74), Expect = 0.86
Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%)
Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78
++PG R P S +P P PP PP PGP PG AG
Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289
Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P G P LP R G P G P +G G
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334
Score = 33.1 bits (74), Expect = 0.86
Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 9/80 (11%)
Query: 55 PPQP--PQPPPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPD 105
PP P P+ PPG G PG+ GP +P G P P +L G
Sbjct: 1332 PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG 1391
Query: 106 SAGAGEPPATPAGLGSGGDR 125
G P TP G G++
Sbjct: 1392 KPGKDGKPGTPGPAGEKGNK 1411
Score = 31.6 bits (70), Expect = 2.5
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%)
Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54
G G +GP +G C+ K + +GF Y +PG + A A+
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164
Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89
+ PG A GP G GP P P GP PGP
Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199
Score = 31.6 bits (70), Expect = 2.5
Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509
P P AR P P P + SSR G G PG P + P G G PG
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421
Query: 510 VAAEPGTPFSIG 521
A PG P S G
Sbjct: 422 CAGSPGLPGSPG 433
Score = 31.6 bits (70), Expect = 2.5
Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%)
Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
R PG PG PP G G PGP P + + S P G+ G PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932
Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569
E G D+G + H +G+ G G +G+ GEK + VP
Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975
Score = 31.6 bits (70), Expect = 2.5
Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%)
Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519
R +PG PG G PGP P S +P G G PG G P S
Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569
G+ TL R R H L +G G G S G +P P P
Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069
Score = 31.2 bits (69), Expect = 3.3
Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%)
Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435
G+ GER G++ P + G + G P SP P G I +R G G
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460
Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485
+ C T+ P PP LPG PG R G G
Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515
P S + P G G PG+ E G
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541
Score = 31.2 bits (69), Expect = 3.3
Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%)
Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
+PG+ G R G PG P L P + G + G PG +PG P +G
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581
+ +G + LG G+ GS P P P L + G
Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129
Query: 582 ALCPRIHEVP 591
P I P
Sbjct: 1130 LGPPGIRGPP 1139
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PGT R G PG LP P G+ G PG G P IG
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339
Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575
+ R D G K S G G G G GE P P P L P
Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386
Score = 30.8 bits (68), Expect = 4.3
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG PG+ + RG PG R +++ P G AG PG+ PG P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435
Score = 30.8 bits (68), Expect = 4.3
Identities = 20/61 (32%), Positives = 24/61 (39%), Gaps = 1/61 (1%)
Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGA-GE 111
P P PP P P PG GP + P GP P + GE + G+ GE
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416
Query: 112 P 112
P
Sbjct: 1417 P 1417
Score = 30.4 bits (67), Expect = 5.6
Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
PG PG A + GG PG P R NS H G+ G PG+ PGTP + G
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786
Score = 29.6 bits (65), Expect = 9.5
Identities = 18/55 (32%), Positives = 22/55 (40%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG G+ P G PG P +L + P G G PG+ EPG P
Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 48.9 bits (115), Expect = 2e-05
Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62
G+ G +GP G + + + +G G A G S TPVP P PP PP
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664
Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119
PGP G PG+ G P GP P +P + G P G P T L
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720
Query: 120 GSGG 123
G G
Sbjct: 721 GCPG 724
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%)
Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84
K LPG G SG Q P P P P PGPA +GP GP P P
Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635
Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124
PG PG A P LS+ G P G PP P LG GD
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511
P + +LPG+PG PP G GEPGP P +L P GK G PG A
Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405
Query: 512 AEPGTPFSIG 521
E G S G
Sbjct: 1406 GEKGNKGSKG 1415
Score = 39.3 bits (90), Expect = 0.012
Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505
+P PP +PG G P S G PGP P S S+ HP G
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279
Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564
G PG A + G P +G T L R D G + GN GS G G P
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338
Query: 565 SGPVPRSRLDP 575
GP P R DP
Sbjct: 1339 KGP-PGVRGDP 1348
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%)
Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504
PG+PG PA G GEPG PGP PR LS S +P P G G
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663
Query: 505 AGGPGVAAEPGTPFSIGR 522
G PG PG P S+G+
Sbjct: 664 PGHPGPQGPPGIPGSLGK 681
Score = 37.0 bits (84), Expect = 0.059
Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56
G +G G MG+ IK Q FR +Y G GP + P
Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370
Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112
Q P PPG P S PG++ P P PG G R +G P S G AG P
Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427
Query: 113 -PATPAGLGSGGDRV 126
P +P G GD V
Sbjct: 428 LPGSPGPPGPPGDIV 442
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47
A G +G SGP G + R G+ L G R G P
Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426
Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88
+P PP PP + PPG G PG GP P P PGP
Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486
Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P LP + G +AG P +P G G
Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523
Score = 35.0 bits (79), Expect = 0.23
Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522
PG PG PA G PG LP L G G PG+ PG P G
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147
Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569
+ ++ + R EK RG G G+ G++ + P
Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200
Score = 34.3 bits (77), Expect = 0.39
Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%)
Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61
A G G G A GD R GF L GA +GP P +
Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225
Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPG A PG G P S P PG PG + ++ +G P G PP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282
Query: 114 ATPAGLGSGG 123
T +G G
Sbjct: 1283 GTAGDMGPPG 1292
Score = 33.9 bits (76), Expect = 0.50
Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%)
Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95
R P + P P P Q PG G PG G P P GP GP P VR
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349
Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125
L ++ L GEP G PP P LG G R
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390
Score = 33.5 bits (75), Expect = 0.66
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118
PGP + G G GP P P GP P LP + S VR G P +G+ P TP
Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113
Query: 119 LGSGG 123
G G
Sbjct: 114 TGPYG 118
Score = 33.5 bits (75), Expect = 0.66
Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%)
Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457
G + EP GT GAP P G AG P L+
Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649
Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
+ +PG PG P G GP +P SL + P G+ G PG+ PG P
Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705
Score = 33.1 bits (74), Expect = 0.86
Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%)
Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
P L + LPG G P S+ GEPG +P S+ G G PG
Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 511 AAEPGTP 517
A PG P
Sbjct: 1038 AGRPGLP 1044
Score = 33.1 bits (74), Expect = 0.86
Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%)
Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78
++PG R P S +P P PP PP PGP PG AG
Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289
Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P G P LP R G P G P +G G
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334
Score = 33.1 bits (74), Expect = 0.86
Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 13/82 (15%)
Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPG-----------PGPALPAVRLSLVRL 101
P P PP P P PG GP + P GP PGPA + +
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKGNKGSK 1414
Query: 102 GEPDSAGAGEPPATPAGLGSGG 123
GEP AG+ P G G
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSG 1436
Score = 31.6 bits (70), Expect = 2.5
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%)
Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54
G G +GP +G C+ K + +GF Y +PG + A A+
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164
Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89
+ PG A GP G GP P P GP PGP
Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199
Score = 31.6 bits (70), Expect = 2.5
Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509
P P AR P P P + SSR G G PG P + P G G PG
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421
Query: 510 VAAEPGTPFSIG 521
A PG P S G
Sbjct: 422 CAGSPGLPGSPG 433
Score = 31.6 bits (70), Expect = 2.5
Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%)
Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
R PG PG PP G G PGP P + + S P G+ G PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932
Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569
E G D+G + H +G+ G G +G+ GEK + VP
Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975
Score = 31.6 bits (70), Expect = 2.5
Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%)
Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519
R +PG PG G PGP P S +P G G PG G P S
Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569
G+ TL R R H L +G G G S G +P P P
Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069
Score = 31.2 bits (69), Expect = 3.3
Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%)
Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435
G+ GER G++ P + G + G P SP P G I +R G G
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460
Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485
+ C T+ P PP LPG PG R G G
Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515
P S + P G G PG+ E G
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541
Score = 31.2 bits (69), Expect = 3.3
Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%)
Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
+PG+ G R G PG P L P + G + G PG +PG P +G
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581
+ +G + LG G+ GS P P P L + G
Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129
Query: 582 ALCPRIHEVP 591
P I P
Sbjct: 1130 LGPPGIRGPP 1139
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PGT R G PG LP P G+ G PG G P IG
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339
Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575
+ R D G K S G G G G GE P P P L P
Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386
Score = 30.8 bits (68), Expect = 4.3
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG PG+ + RG PG R +++ P G AG PG+ PG P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435
Score = 30.4 bits (67), Expect = 5.6
Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
PG PG A + GG PG P R NS H G+ G PG+ PGTP + G
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786
Score = 29.6 bits (65), Expect = 9.5
Identities = 18/55 (32%), Positives = 22/55 (40%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG G+ P G PG P +L + P G G PG+ EPG P
Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 48.9 bits (115), Expect = 2e-05
Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62
G+ G +GP G + + + +G G A G S TPVP P PP PP
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664
Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119
PGP G PG+ G P GP P +P + G P G P T L
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720
Query: 120 GSGG 123
G G
Sbjct: 721 GCPG 724
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%)
Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84
K LPG G SG Q P P P P PGPA +GP GP P P
Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635
Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124
PG PG A P LS+ G P G PP P LG GD
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511
P + +LPG+PG PP G GEPGP P +L P GK G PG A
Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405
Query: 512 AEPGTPFSIG 521
E G S G
Sbjct: 1406 GEKGNKGSKG 1415
Score = 39.3 bits (90), Expect = 0.012
Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505
+P PP +PG G P S G PGP P S S+ HP G
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279
Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564
G PG A + G P +G T L R D G + GN GS G G P
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338
Query: 565 SGPVPRSRLDP 575
GP P R DP
Sbjct: 1339 KGP-PGVRGDP 1348
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%)
Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504
PG+PG PA G GEPG PGP PR LS S +P P G G
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663
Query: 505 AGGPGVAAEPGTPFSIGR 522
G PG PG P S+G+
Sbjct: 664 PGHPGPQGPPGIPGSLGK 681
Score = 37.0 bits (84), Expect = 0.059
Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56
G +G G MG+ IK Q FR +Y G GP + P
Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370
Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112
Q P PPG P S PG++ P P PG G R +G P S G AG P
Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427
Query: 113 -PATPAGLGSGGDRV 126
P +P G GD V
Sbjct: 428 LPGSPGPPGPPGDIV 442
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47
A G +G SGP G + R G+ L G R G P
Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426
Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88
+P PP PP + PPG G PG GP P P PGP
Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486
Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P LP + G +AG P +P G G
Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523
Score = 35.0 bits (79), Expect = 0.23
Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522
PG PG PA G PG LP L G G PG+ PG P G
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147
Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569
+ ++ + R EK RG G G+ G++ + P
Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200
Score = 34.3 bits (77), Expect = 0.39
Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%)
Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61
A G G G A GD R GF L GA +GP P +
Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225
Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPG A PG G P S P PG PG + ++ +G P G PP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282
Query: 114 ATPAGLGSGG 123
T +G G
Sbjct: 1283 GTAGDMGPPG 1292
Score = 33.9 bits (76), Expect = 0.50
Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%)
Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95
R P + P P P Q PG G PG G P P GP GP P VR
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349
Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125
L ++ L GEP G PP P LG G R
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390
Score = 33.5 bits (75), Expect = 0.66
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118
PGP + G G GP P P GP P LP + S VR G P +G+ P TP
Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113
Query: 119 LGSGG 123
G G
Sbjct: 114 TGPYG 118
Score = 33.5 bits (75), Expect = 0.66
Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%)
Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457
G + EP GT GAP P G AG P L+
Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649
Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
+ +PG PG P G GP +P SL + P G+ G PG+ PG P
Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705
Score = 33.1 bits (74), Expect = 0.86
Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%)
Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
P L + LPG G P S+ GEPG +P S+ G G PG
Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 511 AAEPGTP 517
A PG P
Sbjct: 1038 AGRPGLP 1044
Score = 33.1 bits (74), Expect = 0.86
Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%)
Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78
++PG R P S +P P PP PP PGP PG AG
Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289
Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P G P LP R G P G P +G G
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334
Score = 33.1 bits (74), Expect = 0.86
Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 13/82 (15%)
Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPG-----------PGPALPAVRLSLVRL 101
P P PP P P PG GP + P GP PGPA + +
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKGNKGSK 1414
Query: 102 GEPDSAGAGEPPATPAGLGSGG 123
GEP AG+ P G G
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSG 1436
Score = 31.6 bits (70), Expect = 2.5
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%)
Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54
G G +GP +G C+ K + +GF Y +PG + A A+
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164
Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89
+ PG A GP G GP P P GP PGP
Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199
Score = 31.6 bits (70), Expect = 2.5
Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509
P P AR P P P + SSR G G PG P + P G G PG
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421
Query: 510 VAAEPGTPFSIG 521
A PG P S G
Sbjct: 422 CAGSPGLPGSPG 433
Score = 31.6 bits (70), Expect = 2.5
Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%)
Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
R PG PG PP G G PGP P + + S P G+ G PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932
Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569
E G D+G + H +G+ G G +G+ GEK + VP
Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975
Score = 31.6 bits (70), Expect = 2.5
Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%)
Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519
R +PG PG G PGP P S +P G G PG G P S
Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569
G+ TL R R H L +G G G S G +P P P
Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069
Score = 31.2 bits (69), Expect = 3.3
Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%)
Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435
G+ GER G++ P + G + G P SP P G I +R G G
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460
Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485
+ C T+ P PP LPG PG R G G
Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515
P S + P G G PG+ E G
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541
Score = 31.2 bits (69), Expect = 3.3
Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%)
Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
+PG+ G R G PG P L P + G + G PG +PG P +G
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581
+ +G + LG G+ GS P P P L + G
Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129
Query: 582 ALCPRIHEVP 591
P I P
Sbjct: 1130 LGPPGIRGPP 1139
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PGT R G PG LP P G+ G PG G P IG
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339
Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575
+ R D G K S G G G G GE P P P L P
Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386
Score = 30.8 bits (68), Expect = 4.3
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG PG+ + RG PG R +++ P G AG PG+ PG P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435
Score = 30.4 bits (67), Expect = 5.6
Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
PG PG A + GG PG P R NS H G+ G PG+ PGTP + G
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786
Score = 29.6 bits (65), Expect = 9.5
Identities = 18/55 (32%), Positives = 22/55 (40%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG G+ P G PG P +L + P G G PG+ EPG P
Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 48.9 bits (115), Expect = 2e-05
Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 9/124 (7%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVP--PQPPQPP 62
G+ G +GP G + + + +G G A G S TPVP P PP PP
Sbjct: 605 GSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664
Query: 63 --PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGL 119
PGP G PG+ G P GP P +P + G P G P T L
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFP----GPPGPKGDQGFPGTKGSL 720
Query: 120 GSGG 123
G G
Sbjct: 721 GCPG 724
Score = 43.9 bits (102), Expect = 5e-04
Identities = 40/109 (36%), Positives = 42/109 (38%), Gaps = 19/109 (17%)
Query: 34 KLLPGD-GAARRSGPASAQTPVPPQPPQP-PPGPASASGPGAAGPASSP-------PPAG 84
K LPG G SG Q P P P P PGPA +GP GP P P
Sbjct: 577 KGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635
Query: 85 PG-PGPALPAVRLSLVR--------LGEPDSAGAGEPPATPAGLGSGGD 124
PG PG A P LS+ G P G PP P LG GD
Sbjct: 636 PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD 684
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVA 511
P + +LPG+PG PP G GEPGP P +L P GK G PG A
Sbjct: 1348 PGTLKIISLPGSPG--PPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405
Query: 512 AEPGTPFSIG 521
E G S G
Sbjct: 1406 GEKGNKGSKG 1415
Score = 39.3 bits (90), Expect = 0.012
Identities = 43/131 (32%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRS-----LSRSNSLPHPAGGGKA 505
+P PP +PG G P S G PGP P S S+ HP G
Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHP---GPK 1279
Query: 506 GGPGVAAEPGTPFSIGRFATLTLQ-ERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKP 564
G PG A + G P +G T L R D G + GN GS G G P
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGP-PGPIGP 1338
Query: 565 SGPVPRSRLDP 575
GP P R DP
Sbjct: 1339 KGP-PGVRGDP 1348
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 18/78 (23%)
Query: 463 PGTPGTTPPAASSSRG--GEPG----------PGPL----PRS-LSRSNSLPHPAGG-GK 504
PG+PG PA G GEPG PGP PR LS S +P P G G
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663
Query: 505 AGGPGVAAEPGTPFSIGR 522
G PG PG P S+G+
Sbjct: 664 PGHPGPQGPPGIPGSLGK 681
Score = 37.0 bits (84), Expect = 0.059
Identities = 43/135 (31%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQ--------FRTREGFYKLLPGDGAARRSGPASAQTPVPP 56
G +G G MG+ IK Q FR +Y G GP + P
Sbjct: 312 GVKGNRGFPGLMGEDG-IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGP 370
Query: 57 QPPQPPPG-PASASGPGAAGPASSPPPAGPG-PGPALPAVRLSLVRLGEPDSAG-AGEP- 112
Q P PPG P S PG++ P P PG G R +G P S G AG P
Sbjct: 371 QGPSGPPGVPGS---PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPG 427
Query: 113 -PATPAGLGSGGDRV 126
P +P G GD V
Sbjct: 428 LPGSPGPPGPPGDIV 442
Score = 36.2 bits (82), Expect = 0.10
Identities = 42/157 (26%), Positives = 50/157 (31%), Gaps = 36/157 (22%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSG---------------P 47
A G +G SGP G + R G+ L G R G P
Sbjct: 367 ARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSP 426
Query: 48 ASAQTPVPPQPP------QPPPGPASASG-------PGAAGPASSPP------PAGPGPG 88
+P PP PP + PPG G PG GP P P PGP
Sbjct: 427 GLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPP 486
Query: 89 --PALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P LP + G +AG P +P G G
Sbjct: 487 GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG 523
Score = 35.0 bits (79), Expect = 0.23
Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 6/113 (5%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGR 522
PG PG PA G PG LP L G G PG+ PG P G
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147
Query: 523 FATLTLQERRDR------GAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVP 569
+ ++ + R EK RG G G+ G++ + P
Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200
Score = 34.3 bits (77), Expect = 0.39
Identities = 38/130 (29%), Positives = 45/130 (34%), Gaps = 22/130 (16%)
Query: 2 AAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61
A G G G A GD R GF L GA +GP P +
Sbjct: 1177 APPGPRGNPGAQGAKGD--------RGAPGFPGLPGRKGAMGDAGPRG---PTGIEGFPG 1225
Query: 62 PPGPASASGPGAAG----PASSPPPAGPG----PGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPG A PG G P S P PG PG + ++ +G P G PP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKG---PP 1282
Query: 114 ATPAGLGSGG 123
T +G G
Sbjct: 1283 GTAGDMGPPG 1292
Score = 33.9 bits (76), Expect = 0.50
Identities = 34/101 (33%), Positives = 37/101 (36%), Gaps = 21/101 (20%)
Query: 43 RRSGPASAQTPVPPQPP--QPPPGPASASG-PGAAGPASSPPPAGPGPGPALPAVR---- 95
R P + P P P Q PG G PG G P P GP GP P VR
Sbjct: 1293 RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP-KGP--PGVRGDPG 1349
Query: 96 -LSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125
L ++ L GEP G PP P LG G R
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPR 1390
Score = 33.5 bits (75), Expect = 0.66
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Query: 63 PGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSL-VR--LGEPDSAGAGEPPATPAG 118
PGP + G G GP P P GP P LP + S VR G P +G+ P TP
Sbjct: 54 PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGN 113
Query: 119 LGSGG 123
G G
Sbjct: 114 TGPYG 118
Score = 33.5 bits (75), Expect = 0.66
Identities = 33/120 (27%), Positives = 41/120 (34%), Gaps = 31/120 (25%)
Query: 398 GEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLA 457
G + EP GT GAP P G AG P L+
Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPP-----------GEAG----------------PRGELS 649
Query: 458 RTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
+ +PG PG P G GP +P SL + P G+ G PG+ PG P
Sbjct: 650 VSTPVPGPPG---PPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGF-PGPP 705
Score = 33.1 bits (74), Expect = 0.86
Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 3/67 (4%)
Query: 454 PPLARTRTLPGTPGTTPPAA---SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
P L + LPG G P S+ GEPG +P S+ G G PG
Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 511 AAEPGTP 517
A PG P
Sbjct: 1038 AGRPGLP 1044
Score = 33.1 bits (74), Expect = 0.86
Identities = 30/105 (28%), Positives = 34/105 (32%), Gaps = 19/105 (18%)
Query: 35 LLPGDGAARRSGPASAQTPVPPQPPQPP----------------PGPASASGPGAAGPAS 78
++PG R P S +P P PP PP PGP PG AG
Sbjct: 1233 IIPGQ-TGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGP--PGTAGDMG 1289
Query: 79 SPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
P G P LP R G P G P +G G
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334
Score = 33.1 bits (74), Expect = 0.86
Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 13/82 (15%)
Query: 53 PVPPQPPQPPPGPASASGPGAAGPASSPPPAGPG-----------PGPALPAVRLSLVRL 101
P P PP P P PG GP + P GP PGPA + +
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKGNKGSK 1414
Query: 102 GEPDSAGAGEPPATPAGLGSGG 123
GEP AG+ P G G
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSG 1436
Score = 31.6 bits (70), Expect = 2.5
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%)
Query: 5 GAEGGSGPGAAMG--DCAEIKSQFRTREGF--------YKLLPGDGAARRSGPASAQTPV 54
G G +GP +G C+ K + +GF Y +PG + A A+
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGE----QGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164
Query: 55 PPQPPQPPPGPASASGP-GAAGPASSPPPAGPGPGP 89
+ PG A GP G GP P P GP PGP
Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP-PGP 199
Score = 31.6 bits (70), Expect = 2.5
Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 452 PHPPLARTRTLPGTPGTTPPAASSSRGGEPG-PG-PLPRSLSRSNSLPHPAGGGKAGGPG 509
P P AR P P P + SSR G G PG P + P G G PG
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421
Query: 510 VAAEPGTPFSIG 521
A PG P S G
Sbjct: 422 CAGSPGLPGSPG 433
Score = 31.6 bits (70), Expect = 2.5
Identities = 33/120 (27%), Positives = 43/120 (35%), Gaps = 27/120 (22%)
Query: 460 RTLPGTPGTT-PPAASSSRG--------GEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGV 510
R PG PG PP G G PGP P + + S P G+ G PG
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932
Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGG-SGGSGSGGEKPSGPVP 569
E G D+G + H +G+ G G +G+ GEK + VP
Sbjct: 933 KGEQG-----------------DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975
Score = 31.6 bits (70), Expect = 2.5
Identities = 34/111 (30%), Positives = 39/111 (35%), Gaps = 14/111 (12%)
Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519
R +PG PG G PGP P S +P G G PG G P S
Sbjct: 972 RGVPGMPGL------KGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSG-SGGEKPSGPVP 569
G+ TL R R H L +G G G S G +P P P
Sbjct: 1026 KGKRGTLGFPGRAGRPG---LPGIHGL----QGDKGEPGYSEGTRPGPPGP 1069
Score = 31.2 bits (69), Expect = 3.3
Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 34/150 (22%)
Query: 391 GADGERS--GEEEEEEPEAAGTGSAGGAPLSPLPKA--GSITYRFGSAG----------- 435
G+ GER G++ P + G + G P SP P G I +R G G
Sbjct: 401 GSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSP 460
Query: 436 ----------QDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGP 485
+ C T+ P PP LPG PG R G G
Sbjct: 461 GIPGVDGPKGEPGLLC----TQCPYIPGPP-----GLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 486 LPRSLSRSNSLPHPAGGGKAGGPGVAAEPG 515
P S + P G G PG+ E G
Sbjct: 512 SPGSPGNTGLPGFPGFPGAQGDPGLKGEKG 541
Score = 31.2 bits (69), Expect = 3.3
Identities = 32/130 (24%), Positives = 43/130 (33%), Gaps = 12/130 (9%)
Query: 462 LPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
+PG+ G R G PG P L P + G + G PG +PG P +G
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGL-PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080
Query: 522 RFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDPAKVLGT 581
+ +G + LG G+ GS P P P L + G
Sbjct: 1081 K-----------KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL 1129
Query: 582 ALCPRIHEVP 591
P I P
Sbjct: 1130 LGPPGIRGPP 1139
Score = 31.2 bits (69), Expect = 3.3
Identities = 35/112 (31%), Positives = 37/112 (33%), Gaps = 5/112 (4%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PGT R G PG LP P G+ G PG G P IG
Sbjct: 1280 GPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339
Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSRLDP 575
+ R D G K S G G G G GE P P P L P
Sbjct: 1340 GPPGV--RGDPGTLKIISLPGSPG--PPGTPGEPGMQGE-PGPPGPPGNLGP 1386
Score = 30.8 bits (68), Expect = 4.3
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPL----PRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG PG+ + RG PG R +++ P G AG PG+ PG P
Sbjct: 377 PGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP 435
Score = 30.4 bits (67), Expect = 5.6
Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 7/59 (11%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIG 521
PG PG A + GG PG P R NS H G+ G PG+ PGTP + G
Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPG-FPGE--RGNSGEH----GEIGLPGLPGLPGTPGNEG 786
Score = 29.6 bits (65), Expect = 9.5
Identities = 18/55 (32%), Positives = 22/55 (40%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PG G+ P G PG P +L + P G G PG+ EPG P
Sbjct: 1324 PGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPP 1378
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 23/132 (17%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQ-FRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61
A G +G GP G+ E + + GF L G SG A P P P+
Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1164
Query: 62 PPGPASASG-------------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAG 108
PPGP SG PG G + PAGP P P G P G
Sbjct: 1165 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP---------GPPGPPG 1215
Query: 109 AGEPPATPAGLG 120
G + AGLG
Sbjct: 1216 PGIDMSAFAGLG 1227
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLV 99
G A + G A A P P P GP +GP A A PP A PG A
Sbjct: 852 GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA--------G 903
Query: 100 RLGEPDSAGAGEPPATPAGLGSGGDR 125
R+G P S G PP P G G +
Sbjct: 904 RVGPPGSNGNPGPPGPPGPSGKDGPK 929
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/141 (31%), Positives = 49/141 (34%), Gaps = 24/141 (17%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ--TPVPPQP-PQ 60
G G GP A G E + PG DG G A A P P P+
Sbjct: 378 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 437
Query: 61 PPPGPASASGP----------------GAAGPASSPPPAGP--GPGPALPAVRLSLVRLG 102
PPGP A+GP G GP P PAGP PGPA + G
Sbjct: 438 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--ARG 495
Query: 103 EPDSAGAGEPPATPAGLGSGG 123
EP G PP G+ G
Sbjct: 496 EPGGVGPIGPPGERGAPGNRG 516
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 7/80 (8%)
Query: 51 QTPVPPQPPQPPPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGE 103
Q P+ P P+ PPGPA A G PG G P GP P P G+
Sbjct: 200 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259
Query: 104 PDSAGAGEPPATPAGLGSGG 123
P AG PP G G
Sbjct: 260 PGKAGERGPPGPQGARGFPG 279
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/123 (26%), Positives = 43/123 (34%), Gaps = 2/123 (1%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGA--ARRSGPASAQTPVPPQPPQPP 62
GAEG GP G + + E + LPG ++ P ++ PP P PP
Sbjct: 966 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025
Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122
A PG G + P G + R +G P + G P G
Sbjct: 1026 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1085
Query: 123 GDR 125
GDR
Sbjct: 1086 GDR 1088
Score = 40.8 bits (94), Expect = 0.004
Identities = 43/120 (35%), Positives = 45/120 (37%), Gaps = 33/120 (27%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
GA G GP A G PG A R P S P PP PP G
Sbjct: 885 GARGAQGPPGATG------------------FPG-AAGRVGPPGSNGNPGPPGPP----G 921
Query: 65 PASASGP-GAAGPASSPPPAG-PG-PGPALPAVRLSLVRLGEP--DSAGAGEPPATPAGL 119
P+ GP GA G + P AG PG GPA P GEP D E P P GL
Sbjct: 922 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-----GEKGEPGDDGPSGAEGPPGPQGL 976
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/113 (33%), Positives = 43/113 (38%), Gaps = 24/113 (21%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG----GGKAGGPGVAAEPGTPFS 519
G PG PA G PGP S LP P G GGK G GV E G P
Sbjct: 642 GPPGPAGPAGERGEQGAPGP-------SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 694
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLG-NISRGGSGGSGSGGEK----PSGP 567
+G R +RG E + G RG G G+ G K P+GP
Sbjct: 695 VG--------PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739
Score = 38.5 bits (88), Expect = 0.020
Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 20/130 (15%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP-- 61
GA G +GP GD E + EG PG DG +GP P +
Sbjct: 756 GAAGIAGPKGDRGDVGE-----KGPEG----APGKDGGRGLTGPIGPPGPAGANGEKGEV 806
Query: 62 -PPGPASASG----PGAAGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPGPA ++G PG G P P AGP P + G+ AGA P
Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866
Query: 114 ATPAGLGSGG 123
G G
Sbjct: 867 GPSGAPGPQG 876
Score = 38.1 bits (87), Expect = 0.027
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 463 PGTPGTTPPAASSSRGGEPGP-GPL-PRSLSRSNSLPHPAGG----------GKAGGPGV 510
PG PG A + GE GP GP R + LP G G+AG PGV
Sbjct: 248 PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 307
Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-SRGGSGGSGSGGEKPSGPV 568
E G+P G + RG E R G +RG G G G P GPV
Sbjct: 308 KGESGSPGENGSPGPM-----GPRGLPGERGRTGPAGAAGARGNDGQPGPAG--PPGPV 359
Score = 38.1 bits (87), Expect = 0.027
Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 19/104 (18%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP----------GAAGPASSPPPAGPGPGP 89
G SG P P+ PG +GP G GPA P P GP GP
Sbjct: 306 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 365
Query: 90 ALPAVRLSLVRLGEPDSAG-------AGEP--PATPAGLGSGGD 124
P + G + G GEP P +P G+ G+
Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409
Score = 37.7 bits (86), Expect = 0.035
Identities = 35/123 (28%), Positives = 38/123 (30%), Gaps = 13/123 (10%)
Query: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60
M G G GP A G +GF G SGP + P P PP
Sbjct: 203 MGPMGPRGPPGPAGAPGP-----------QGFQGNPGEPGEPGVSGPMGPRGP--PGPPG 249
Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
P A PG AG P P G P P + G P GA P G
Sbjct: 250 KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309
Query: 121 SGG 123
G
Sbjct: 310 ESG 312
Score = 37.7 bits (86), Expect = 0.035
Identities = 39/128 (30%), Positives = 42/128 (32%), Gaps = 31/128 (24%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
G+ G GP G+ R R G P A R PP P P G
Sbjct: 318 GSPGPMGPRGLPGE--------RGRTG-----PAGAAGARGNDGQPGPAGPPGPVGPAGG 364
Query: 65 PASASGPGA---AGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT--- 115
P PGA AGP + P GP P P G P AGA P T
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP---------GSPGPAGASGNPGTDGI 415
Query: 116 PAGLGSGG 123
P GS G
Sbjct: 416 PGAKGSAG 423
Score = 37.7 bits (86), Expect = 0.035
Identities = 42/127 (33%), Positives = 48/127 (37%), Gaps = 22/127 (17%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPP-----QPP 59
G G +GP A GD R G L G R G A Q V P +
Sbjct: 534 GPSGLAGPKGANGDPG--------RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 585
Query: 60 QP-PPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111
+P PPGP A G PG G P AG P P +R + GE +AG
Sbjct: 586 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP-P 644
Query: 112 PPATPAG 118
PA PAG
Sbjct: 645 GPAGPAG 651
Score = 37.7 bits (86), Expect = 0.035
Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 4/109 (3%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PG T PA R G PG P + G G PG PG+P G
Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG-- 1080
Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSR 572
T +R + GA+ G +RG G G G+K P R
Sbjct: 1081 PTGKQGDRGEAGAQGPMGPSGPAG--ARGIQGPQGPRGDKGEAGEPGER 1127
Score = 37.4 bits (85), Expect = 0.046
Identities = 56/200 (28%), Positives = 67/200 (33%), Gaps = 28/200 (14%)
Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGG----APLSPLPKAGSITYRFGSAGQDTQFC 441
AA AG G+R G+ E+ PE A G GG P+ P AG+ G G+
Sbjct: 757 AAGIAGPKGDR-GDVGEKGPEGA-PGKDGGRGLTGPIGPPGPAGAN----GEKGE----- 805
Query: 442 LWDLTEDVLYPHPP-LARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA 500
V P P A R PG G T P + G PG P +
Sbjct: 806 -------VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK- 857
Query: 501 GGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSG 560
G AG PG G P G T + RGA+ G R G GS
Sbjct: 858 --GDAGAPGPQGPSGAPGPQG--PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN 913
Query: 561 GEKPSGPVPRSRLDPAKVLG 580
P P P + P G
Sbjct: 914 PGPPGPPGPSGKDGPKGARG 933
Score = 37.0 bits (84), Expect = 0.059
Identities = 34/114 (29%), Positives = 41/114 (35%), Gaps = 20/114 (17%)
Query: 12 PGAAMGDCAEI-KSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPGPASASG 70
P G+C I + T G PG ++ P + V P+ P P GPA G
Sbjct: 78 PEIPFGECCPICPTDLATASG----QPGP-KGQKGEPGDIKDIVGPKGPPGPQGPAGEQG 132
Query: 71 P----GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
P G G +P P G P P G P G PP P GLG
Sbjct: 133 PRGDRGDKGEKGAPGPRGRDGEPGTP---------GNPGPPGPPGPPG-PPGLG 176
Score = 36.6 bits (83), Expect = 0.078
Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 15/55 (27%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PGTPG+ PA +S G PG + P G AG PG+A PG P
Sbjct: 395 PGTPGSPGPAGAS---GNPGTDGI------------PGAKGSAGAPGIAGAPGFP 434
Score = 36.2 bits (82), Expect = 0.10
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 23/112 (20%)
Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519
R LPGTPGT P +S G PG P +P G+ G G+A G
Sbjct: 719 RGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP-----GERGAAGIAGPKGDRGD 769
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK----PSGP 567
+G E+ GA + G I G G +G+ GEK P GP
Sbjct: 770 VG--------EKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGP 811
Score = 35.8 bits (81), Expect = 0.13
Identities = 49/161 (30%), Positives = 56/161 (34%), Gaps = 50/161 (31%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP 61
A G +G GP G GF PG GA +GP A+ P Q P+
Sbjct: 343 ARGNDGQPGPAGPPGPVGPAGGP-----GF----PGAPGAKGEAGPTGARGPEGAQGPRG 393
Query: 62 PPG------PASASG-------PGAAGPASSPPPAG----------PGP----GPALPAV 94
PG PA ASG PGA G A +P AG PGP GP P
Sbjct: 394 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 453
Query: 95 RLSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125
+ + GEP AG P P G G R
Sbjct: 454 QTGEPGIAGFKGEQGPKGEPGPAG---PQGAPGPAGEEGKR 491
Score = 35.8 bits (81), Expect = 0.13
Identities = 58/193 (30%), Positives = 62/193 (32%), Gaps = 44/193 (22%)
Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445
+A A GA GER E P AG GA P K G AGQ
Sbjct: 814 SAGARGAPGERG---ETGPPGPAGFAGPPGADGQPGAKGEQ-----GEAGQKG------- 858
Query: 446 TEDVLYPHPPLARTRTLP-GTPGTTPPAASSSRGGEPGPGPLPRSLSR-----SNSLPHP 499
D P P P G G T P + G PG P + R SN P P
Sbjct: 859 --DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916
Query: 500 AG----GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSG 555
G GK G G + G P GR LQ EK G G
Sbjct: 917 PGPPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEK-------------GEPG 960
Query: 556 GSG-SGGEKPSGP 567
G SG E P GP
Sbjct: 961 DDGPSGAEGPPGP 973
Score = 35.8 bits (81), Expect = 0.13
Identities = 46/176 (26%), Positives = 60/176 (34%), Gaps = 16/176 (9%)
Query: 357 EGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGA 416
EG A G + V D T A A A G G + G A G
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQG- 1095
Query: 417 PLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSS 476
P+ P AG+ + + + + E L H + LPG PG + +S
Sbjct: 1096 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1155
Query: 477 RGGEPGP----GPL-PRSLSRSNSLPHPAGG----------GKAGGPGVAAEPGTP 517
G GP GP+ P +N +P P G G AG PG PG P
Sbjct: 1156 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1211
Score = 35.4 bits (80), Expect = 0.17
Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 15/77 (19%)
Query: 460 RTLPGTPGTTPPA-ASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAG--------GP 508
R LPG G T PA A+ +RG G+PGP P + + P G G GP
Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385
Query: 509 ----GVAAEPGTPFSIG 521
G EPGTP S G
Sbjct: 386 EGAQGPRGEPGTPGSPG 402
Score = 35.4 bits (80), Expect = 0.17
Identities = 21/68 (30%), Positives = 25/68 (36%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PG P+ G PGP P RS G G PG PG + F
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1223
Query: 524 ATLTLQER 531
A L +E+
Sbjct: 1224 AGLGPREK 1231
Score = 35.0 bits (79), Expect = 0.23
Identities = 39/134 (29%), Positives = 43/134 (32%), Gaps = 15/134 (11%)
Query: 383 AEEAATAAGADGERSGEEEEEEPEAAGT-GSAGGAPLSPLPKAGSITYRFGSAGQDTQFC 441
A A AG G R E + GT GS G A S P I GSAG
Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG--- 426
Query: 442 LWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG 501
+ P R PG G T P + GEPG + P
Sbjct: 427 --------IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG---IAGFKGEQGPKGEPGP 475
Query: 502 GGKAGGPGVAAEPG 515
G G PG A E G
Sbjct: 476 AGPQGAPGPAGEEG 489
Score = 33.9 bits (76), Expect = 0.50
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 5/67 (7%)
Query: 453 HPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG----GKAGGP 508
+P L + G PG + S G PGP PR L PAG G G P
Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-PRGLPGERGRTGPAGAAGARGNDGQP 350
Query: 509 GVAAEPG 515
G A PG
Sbjct: 351 GPAGPPG 357
Score = 33.9 bits (76), Expect = 0.50
Identities = 37/138 (26%), Positives = 45/138 (32%), Gaps = 23/138 (16%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD----GAARRSGPASAQ-------TP 53
G G GP A G+ + + + LPG GAA GPA P
Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659
Query: 54 VP------PQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSA 107
P P PP PP G G A +P GP P R G P +
Sbjct: 660 GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER------GSPGAQ 713
Query: 108 GAGEPPATPAGLGSGGDR 125
G P P G+ G +
Sbjct: 714 GLQGPRGLPGTPGTDGPK 731
Score = 33.1 bits (74), Expect = 0.86
Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 6/74 (8%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRGGEPG----PGPLPRSLSRSNS--LPHPAGGGKAGG 507
P L R L G PG P G PG PGP +R + P G G
Sbjct: 554 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 613
Query: 508 PGVAAEPGTPFSIG 521
PG A E G P + G
Sbjct: 614 PGKAGEKGLPGAPG 627
Score = 32.7 bits (73), Expect = 1.1
Identities = 32/124 (25%), Positives = 43/124 (34%), Gaps = 14/124 (11%)
Query: 6 AEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPP--- 62
A G GP G+ +IK ++ G GPA Q P + +
Sbjct: 96 ASGQPGPKGQKGEPGDIKD----------IVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145
Query: 63 PGPASASG-PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGS 121
PGP G PG G P P GP P L + + G + AG + +G
Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP 205
Query: 122 GGDR 125
G R
Sbjct: 206 MGPR 209
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/97 (30%), Positives = 32/97 (32%), Gaps = 13/97 (13%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPG----PASASGPGAAGPASSPPPA---GPGPGPALP 92
G GP A P P Q PPG P G AGP GP P
Sbjct: 723 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 782
Query: 93 AVRLSLVRLGEPDSAGA-GE-----PPATPAGLGSGG 123
R +G P AGA GE PP G+ G
Sbjct: 783 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 819
Score = 32.0 bits (71), Expect = 1.9
Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 24/82 (29%)
Query: 464 GTPGTTPPAASSSRGGEPG----------PGP-----------LPRSLSRSN--SLPHPA 500
G PG PA GEPG PGP LP LP P+
Sbjct: 942 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001
Query: 501 GG-GKAGGPGVAAEPGTPFSIG 521
G GK G PG + + G P +G
Sbjct: 1002 GEPGKQGAPGASGDRGPPGPVG 1023
Score = 31.6 bits (70), Expect = 2.5
Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 14/139 (10%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP----LPKAGSITYRFGSAGQDTQFCLWDLT 446
G G + E AG A G P P LP A +T R G AG +
Sbjct: 522 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 581
Query: 447 EDVLYPHPPLAR-TRTLPGTPGTTPPAASSSRGGEPG----PGP-----LPRSLSRSNSL 496
+ P PP + R PG G P ++ G+ G PG LP + +
Sbjct: 582 GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 641
Query: 497 PHPAGGGKAGGPGVAAEPG 515
P G AG G PG
Sbjct: 642 GPPGPAGPAGERGEQGAPG 660
Score = 31.6 bits (70), Expect = 2.5
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 10/68 (14%)
Query: 57 QPPQPPPGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT 115
Q P+ PG GP GA+GPA P GP +P GE +AG P
Sbjct: 716 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP---------GERGAAGIAGPKGD 766
Query: 116 PAGLGSGG 123
+G G
Sbjct: 767 RGDVGEKG 774
Score = 31.2 bits (69), Expect = 3.3
Identities = 54/216 (25%), Positives = 64/216 (29%), Gaps = 43/216 (19%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVL 450
GA G R + E P G G P P G + + + +
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPG-------------PGPLPRSLSRSNSLP 497
P P R PG G P GEPG PGP P
Sbjct: 204 GPMGP----RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-PGKPGDDGEAG 258
Query: 498 HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-----SRG 552
P G+ G PG G P + G K H+ Y L + G
Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPG------------LPGVKGHRGYPGLDGAKGEAGAPG 306
Query: 553 GSGGSGSGGEK----PSGP--VP--RSRLDPAKVLG 580
G SGS GE P GP +P R R PA G
Sbjct: 307 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG 342
Score = 30.4 bits (67), Expect = 5.6
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP-GAAGPASSPPPAGP-GP 87
GA GP + P P Q G A A GP G +GPA + GP GP
Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114
Score = 30.0 bits (66), Expect = 7.3
Identities = 41/136 (30%), Positives = 51/136 (37%), Gaps = 14/136 (10%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP--LPKAGSITYRFGSAGQDTQFCLWDLTED 448
GA GE + E + G + G P+ P LP T G+AG D
Sbjct: 297 GAKGEAGAPGVKGESGSPGENGSPG-PMGPRGLPGERGRTGPAGAAGARGN----DGQPG 351
Query: 449 VLYPHPPL--ARTRTLPGTPGTTPPAA-SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKA 505
P P+ A PG PG A + +RG E GP R + P PAG +
Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP--RGEPGTPGSPGPAGA--S 407
Query: 506 GGPGVAAEPGTPFSIG 521
G PG PG S G
Sbjct: 408 GNPGTDGIPGAKGSAG 423
Score = 30.0 bits (66), Expect = 7.3
Identities = 41/149 (27%), Positives = 49/149 (32%), Gaps = 31/149 (20%)
Query: 5 GAEGGSGPGAAMGDCAEIK-SQFRTREGFYKLLPGD-------GAARRSGPASAQTPVPP 56
G +G +GP G E + F+ +G K PG G A G A+
Sbjct: 441 GPQGATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 499
Query: 57 QPPQPPPGPASASG-------PGAAGPASSPPPAGPG-----------PG----PALPAV 94
P PPG A G G AGP +P GP PG P LP
Sbjct: 500 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 559
Query: 95 RLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
R R G+ G P P G G
Sbjct: 560 RGLTGRPGDAGPQGKVGPSGAPGEDGRPG 588
Score = 29.6 bits (65), Expect = 9.5
Identities = 34/98 (34%), Positives = 37/98 (37%), Gaps = 23/98 (23%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ----------TP 53
G G GP G E REG PG DG R G A + P
Sbjct: 1017 GPPGPVGPPGLTGPAGE-----PGREGS----PGADGPPGRDGAAGVKGDRGETGAVGAP 1067
Query: 54 VPPQPPQPPPGPASASG-PGAAGPASSPPPAGPGPGPA 90
P PP PGPA +G G G A + P GP GPA
Sbjct: 1068 GAPGPP-GSPGPAGPTGKQGDRGEAGAQGPMGPS-GPA 1103
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 48.5 bits (114), Expect = 2e-05
Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 23/132 (17%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQ-FRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQP 61
A G +G GP G+ E + + GF L G SG A P P P+
Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRG 1095
Query: 62 PPGPASASG-------------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAG 108
PPGP SG PG G + PAGP P P G P G
Sbjct: 1096 PPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP---------GPPGPPG 1146
Query: 109 AGEPPATPAGLG 120
G + AGLG
Sbjct: 1147 PGIDMSAFAGLG 1158
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLV 99
G A + G A A P P P GP +GP A A PP A PG A
Sbjct: 783 GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA--------G 834
Query: 100 RLGEPDSAGAGEPPATPAGLGSGGDR 125
R+G P S G PP P G G +
Sbjct: 835 RVGPPGSNGNPGPPGPPGPSGKDGPK 860
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/141 (31%), Positives = 49/141 (34%), Gaps = 24/141 (17%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ--TPVPPQP-PQ 60
G G GP A G E + PG DG G A A P P P+
Sbjct: 309 GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR 368
Query: 61 PPPGPASASGP----------------GAAGPASSPPPAGP--GPGPALPAVRLSLVRLG 102
PPGP A+GP G GP P PAGP PGPA + G
Sbjct: 369 GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG--ARG 426
Query: 103 EPDSAGAGEPPATPAGLGSGG 123
EP G PP G+ G
Sbjct: 427 EPGGVGPIGPPGERGAPGNRG 447
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/80 (33%), Positives = 30/80 (37%), Gaps = 7/80 (8%)
Query: 51 QTPVPPQPPQPPPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGE 103
Q P+ P P+ PPGPA A G PG G P GP P P G+
Sbjct: 131 QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190
Query: 104 PDSAGAGEPPATPAGLGSGG 123
P AG PP G G
Sbjct: 191 PGKAGERGPPGPQGARGFPG 210
Score = 41.2 bits (95), Expect = 0.003
Identities = 32/123 (26%), Positives = 43/123 (34%), Gaps = 2/123 (1%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGA--ARRSGPASAQTPVPPQPPQPP 62
GAEG GP G + + E + LPG ++ P ++ PP P PP
Sbjct: 897 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 956
Query: 63 PGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLGSG 122
A PG G + P G + R +G P + G P G
Sbjct: 957 GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQ 1016
Query: 123 GDR 125
GDR
Sbjct: 1017 GDR 1019
Score = 40.8 bits (94), Expect = 0.004
Identities = 43/120 (35%), Positives = 45/120 (37%), Gaps = 33/120 (27%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
GA G GP A G PG A R P S P PP PP G
Sbjct: 816 GARGAQGPPGATG------------------FPG-AAGRVGPPGSNGNPGPPGPP----G 852
Query: 65 PASASGP-GAAGPASSPPPAG-PG-PGPALPAVRLSLVRLGEP--DSAGAGEPPATPAGL 119
P+ GP GA G + P AG PG GPA P GEP D E P P GL
Sbjct: 853 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP-----GEKGEPGDDGPSGAEGPPGPQGL 907
Score = 40.4 bits (93), Expect = 0.005
Identities = 38/113 (33%), Positives = 43/113 (38%), Gaps = 24/113 (21%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG----GGKAGGPGVAAEPGTPFS 519
G PG PA G PGP S LP P G GGK G GV E G P
Sbjct: 573 GPPGPAGPAGERGEQGAPGP-------SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLG-NISRGGSGGSGSGGEK----PSGP 567
+G R +RG E + G RG G G+ G K P+GP
Sbjct: 626 VG--------PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670
Score = 38.5 bits (88), Expect = 0.020
Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 20/130 (15%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP-- 61
GA G +GP GD E + EG PG DG +GP P +
Sbjct: 687 GAAGIAGPKGDRGDVGE-----KGPEG----APGKDGGRGLTGPIGPPGPAGANGEKGEV 737
Query: 62 -PPGPASASG----PGAAGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPP 113
PPGPA ++G PG G P P AGP P + G+ AGA P
Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797
Query: 114 ATPAGLGSGG 123
G G
Sbjct: 798 GPSGAPGPQG 807
Score = 38.1 bits (87), Expect = 0.027
Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 20/119 (16%)
Query: 463 PGTPGTTPPAASSSRGGEPGP-GPL-PRSLSRSNSLPHPAGG----------GKAGGPGV 510
PG PG A + GE GP GP R + LP G G+AG PGV
Sbjct: 179 PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 238
Query: 511 AAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-SRGGSGGSGSGGEKPSGPV 568
E G+P G + RG E R G +RG G G G P GPV
Sbjct: 239 KGESGSPGENGSPGPM-----GPRGLPGERGRTGPAGAAGARGNDGQPGPAG--PPGPV 290
Score = 38.1 bits (87), Expect = 0.027
Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 19/104 (18%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP----------GAAGPASSPPPAGPGPGP 89
G SG P P+ PG +GP G GPA P P GP GP
Sbjct: 237 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 296
Query: 90 ALPAVRLSLVRLGEPDSAG-------AGEP--PATPAGLGSGGD 124
P + G + G GEP P +P G+ G+
Sbjct: 297 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340
Score = 37.7 bits (86), Expect = 0.035
Identities = 35/123 (28%), Positives = 38/123 (30%), Gaps = 13/123 (10%)
Query: 1 MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQ 60
M G G GP A G +GF G SGP + P P PP
Sbjct: 134 MGPMGPRGPPGPAGAPGP-----------QGFQGNPGEPGEPGVSGPMGPRGP--PGPPG 180
Query: 61 PPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPATPAGLG 120
P A PG AG P P G P P + G P GA P G
Sbjct: 181 KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240
Query: 121 SGG 123
G
Sbjct: 241 ESG 243
Score = 37.7 bits (86), Expect = 0.035
Identities = 39/128 (30%), Positives = 42/128 (32%), Gaps = 31/128 (24%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
G+ G GP G+ R R G P A R PP P P G
Sbjct: 249 GSPGPMGPRGLPGE--------RGRTG-----PAGAAGARGNDGQPGPAGPPGPVGPAGG 295
Query: 65 PASASGPGA---AGPASSPPP---AGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT--- 115
P PGA AGP + P GP P P G P AGA P T
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP---------GSPGPAGASGNPGTDGI 346
Query: 116 PAGLGSGG 123
P GS G
Sbjct: 347 PGAKGSAG 354
Score = 37.7 bits (86), Expect = 0.035
Identities = 42/127 (33%), Positives = 48/127 (37%), Gaps = 22/127 (17%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPP-----QPP 59
G G +GP A GD R G L G R G A Q V P +
Sbjct: 465 GPSGLAGPKGANGDPG--------RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG 516
Query: 60 QP-PPGPASASG-------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGE 111
+P PPGP A G PG G P AG P P +R + GE +AG
Sbjct: 517 RPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP-P 575
Query: 112 PPATPAG 118
PA PAG
Sbjct: 576 GPAGPAG 582
Score = 37.7 bits (86), Expect = 0.035
Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 4/109 (3%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PG T PA R G PG P + G G PG PG+P G
Sbjct: 954 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAG-- 1011
Query: 524 ATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEKPSGPVPRSR 572
T +R + GA+ G +RG G G G+K P R
Sbjct: 1012 PTGKQGDRGEAGAQGPMGPSGPAG--ARGIQGPQGPRGDKGEAGEPGER 1058
Score = 37.4 bits (85), Expect = 0.046
Identities = 56/200 (28%), Positives = 67/200 (33%), Gaps = 28/200 (14%)
Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGG----APLSPLPKAGSITYRFGSAGQDTQFC 441
AA AG G+R G+ E+ PE A G GG P+ P AG+ G G+
Sbjct: 688 AAGIAGPKGDR-GDVGEKGPEGA-PGKDGGRGLTGPIGPPGPAGAN----GEKGE----- 736
Query: 442 LWDLTEDVLYPHPP-LARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPA 500
V P P A R PG G T P + G PG P +
Sbjct: 737 -------VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK- 788
Query: 501 GGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSG 560
G AG PG G P G T + RGA+ G R G GS
Sbjct: 789 --GDAGAPGPQGPSGAPGPQG--PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN 844
Query: 561 GEKPSGPVPRSRLDPAKVLG 580
P P P + P G
Sbjct: 845 PGPPGPPGPSGKDGPKGARG 864
Score = 36.6 bits (83), Expect = 0.078
Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 15/55 (27%)
Query: 463 PGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTP 517
PGTPG+ PA +S G PG + P G AG PG+A PG P
Sbjct: 326 PGTPGSPGPAGAS---GNPGTDGI------------PGAKGSAGAPGIAGAPGFP 365
Score = 36.2 bits (82), Expect = 0.10
Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 14/82 (17%)
Query: 43 RRSGPASAQTPVPPQPPQPPPGPASASGP----GAAGPASSPPPAGPGPGPALPAVRLSL 98
++ P + V P+ P P GPA GP G G +P P G P P
Sbjct: 36 QKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP------ 89
Query: 99 VRLGEPDSAGAGEPPATPAGLG 120
G P G PP P GLG
Sbjct: 90 ---GNPGPPGPPGPPG-PPGLG 107
Score = 36.2 bits (82), Expect = 0.10
Identities = 38/142 (26%), Positives = 42/142 (29%), Gaps = 36/142 (25%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRSGPASAQTPVPPQPPQPPPG 64
G G GP GD E K PG R P + P PP PP PPG
Sbjct: 57 GPAGEQGPRGDRGDKGE------------KGAPGP-RGRDGEPGTPGNPGPPGPPG-PPG 102
Query: 65 PASASG----------------------PGAAGPASSPPPAGPGPGPALPAVRLSLVRLG 102
P G G GP P GP P + + G
Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162
Query: 103 EPDSAGAGEPPATPAGLGSGGD 124
EP +G P P G GD
Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGD 184
Score = 36.2 bits (82), Expect = 0.10
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 23/112 (20%)
Query: 460 RTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFS 519
R LPGTPGT P +S G PG P +P G+ G G+A G
Sbjct: 650 RGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP-----GERGAAGIAGPKGDRGD 700
Query: 520 IGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSGGSGSGGEK----PSGP 567
+G E+ GA + G I G G +G+ GEK P GP
Sbjct: 701 VG--------EKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGP 742
Score = 35.8 bits (81), Expect = 0.13
Identities = 49/161 (30%), Positives = 56/161 (34%), Gaps = 50/161 (31%)
Query: 3 AGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQTPVPPQPPQP 61
A G +G GP G GF PG GA +GP A+ P Q P+
Sbjct: 274 ARGNDGQPGPAGPPGPVGPAGGP-----GF----PGAPGAKGEAGPTGARGPEGAQGPRG 324
Query: 62 PPG------PASASG-------PGAAGPASSPPPAG----------PGP----GPALPAV 94
PG PA ASG PGA G A +P AG PGP GP P
Sbjct: 325 EPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 384
Query: 95 RLSLVRL----------GEPDSAGAGEPPATPAGLGSGGDR 125
+ + GEP AG P P G G R
Sbjct: 385 QTGEPGIAGFKGEQGPKGEPGPAG---PQGAPGPAGEEGKR 422
Score = 35.8 bits (81), Expect = 0.13
Identities = 58/193 (30%), Positives = 62/193 (32%), Gaps = 44/193 (22%)
Query: 386 AATAAGADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDL 445
+A A GA GER E P AG GA P K G AGQ
Sbjct: 745 SAGARGAPGERG---ETGPPGPAGFAGPPGADGQPGAKGEQ-----GEAGQKG------- 789
Query: 446 TEDVLYPHPPLARTRTLP-GTPGTTPPAASSSRGGEPGPGPLPRSLSR-----SNSLPHP 499
D P P P G G T P + G PG P + R SN P P
Sbjct: 790 --DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847
Query: 500 AG----GGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNISRGGSG 555
G GK G G + G P GR LQ EK G G
Sbjct: 848 PGPPGPSGKDGPKGARGDSGPP---GRAGEPGLQGPAGPPGEK-------------GEPG 891
Query: 556 GSG-SGGEKPSGP 567
G SG E P GP
Sbjct: 892 DDGPSGAEGPPGP 904
Score = 35.8 bits (81), Expect = 0.13
Identities = 46/176 (26%), Positives = 60/176 (34%), Gaps = 16/176 (9%)
Query: 357 EGRVVARGHGHKSWVNAVAFDPYTTRAEEAATAAGADGERSGEEEEEEPEAAGTGSAGGA 416
EG A G + V D T A A A G G + G A G
Sbjct: 968 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQG- 1026
Query: 417 PLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSS 476
P+ P AG+ + + + + E L H + LPG PG + +S
Sbjct: 1027 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASG 1086
Query: 477 RGGEPGP----GPL-PRSLSRSNSLPHPAGG----------GKAGGPGVAAEPGTP 517
G GP GP+ P +N +P P G G AG PG PG P
Sbjct: 1087 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1142
Score = 35.4 bits (80), Expect = 0.17
Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 15/77 (19%)
Query: 460 RTLPGTPGTTPPA-ASSSRG--GEPGPGPLPRSLSRSNSLPHPAGGGKAG--------GP 508
R LPG G T PA A+ +RG G+PGP P + + P G G GP
Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316
Query: 509 ----GVAAEPGTPFSIG 521
G EPGTP S G
Sbjct: 317 EGAQGPRGEPGTPGSPG 333
Score = 35.4 bits (80), Expect = 0.17
Identities = 21/68 (30%), Positives = 25/68 (36%)
Query: 464 GTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKAGGPGVAAEPGTPFSIGRF 523
G PG P+ G PGP P RS G G PG PG + F
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1154
Query: 524 ATLTLQER 531
A L +E+
Sbjct: 1155 AGLGPREK 1162
Score = 35.0 bits (79), Expect = 0.23
Identities = 39/134 (29%), Positives = 43/134 (32%), Gaps = 15/134 (11%)
Query: 383 AEEAATAAGADGERSGEEEEEEPEAAGT-GSAGGAPLSPLPKAGSITYRFGSAGQDTQFC 441
A A AG G R E + GT GS G A S P I GSAG
Sbjct: 301 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG--- 357
Query: 442 LWDLTEDVLYPHPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAG 501
+ P R PG G T P + GEPG + P
Sbjct: 358 --------IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG---IAGFKGEQGPKGEPGP 406
Query: 502 GGKAGGPGVAAEPG 515
G G PG A E G
Sbjct: 407 AGPQGAPGPAGEEG 420
Score = 33.9 bits (76), Expect = 0.50
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 5/67 (7%)
Query: 453 HPPLARTRTLPGTPGTTPPAASSSRGGEPGPGPLPRSLSRSNSLPHPAGG----GKAGGP 508
+P L + G PG + S G PGP PR L PAG G G P
Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-PRGLPGERGRTGPAGAAGARGNDGQP 281
Query: 509 GVAAEPG 515
G A PG
Sbjct: 282 GPAGPPG 288
Score = 33.9 bits (76), Expect = 0.50
Identities = 37/138 (26%), Positives = 45/138 (32%), Gaps = 23/138 (16%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGD----GAARRSGPASAQ-------TP 53
G G GP A G+ + + + LPG GAA GPA P
Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 590
Query: 54 VP------PQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSA 107
P P PP PP G G A +P GP P R G P +
Sbjct: 591 GPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGER------GSPGAQ 644
Query: 108 GAGEPPATPAGLGSGGDR 125
G P P G+ G +
Sbjct: 645 GLQGPRGLPGTPGTDGPK 662
Score = 33.1 bits (74), Expect = 0.86
Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 6/74 (8%)
Query: 454 PPLARTRTLPGTPGTTPPAASSSRGGEPG----PGPLPRSLSRSNS--LPHPAGGGKAGG 507
P L R L G PG P G PG PGP +R + P G G
Sbjct: 485 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 544
Query: 508 PGVAAEPGTPFSIG 521
PG A E G P + G
Sbjct: 545 PGKAGEKGLPGAPG 558
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/97 (30%), Positives = 32/97 (32%), Gaps = 13/97 (13%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPG----PASASGPGAAGPASSPPPA---GPGPGPALP 92
G GP A P P Q PPG P G AGP GP P
Sbjct: 654 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 713
Query: 93 AVRLSLVRLGEPDSAGA-GE-----PPATPAGLGSGG 123
R +G P AGA GE PP G+ G
Sbjct: 714 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 750
Score = 32.0 bits (71), Expect = 1.9
Identities = 26/82 (31%), Positives = 30/82 (36%), Gaps = 24/82 (29%)
Query: 464 GTPGTTPPAASSSRGGEPG----------PGP-----------LPRSLSRSN--SLPHPA 500
G PG PA GEPG PGP LP LP P+
Sbjct: 873 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932
Query: 501 GG-GKAGGPGVAAEPGTPFSIG 521
G GK G PG + + G P +G
Sbjct: 933 GEPGKQGAPGASGDRGPPGPVG 954
Score = 31.6 bits (70), Expect = 2.5
Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 14/139 (10%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP----LPKAGSITYRFGSAGQDTQFCLWDLT 446
G G + E AG A G P P LP A +T R G AG +
Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 512
Query: 447 EDVLYPHPPLAR-TRTLPGTPGTTPPAASSSRGGEPG----PGP-----LPRSLSRSNSL 496
+ P PP + R PG G P ++ G+ G PG LP + +
Sbjct: 513 GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 572
Query: 497 PHPAGGGKAGGPGVAAEPG 515
P G AG G PG
Sbjct: 573 GPPGPAGPAGERGEQGAPG 591
Score = 31.6 bits (70), Expect = 2.5
Identities = 22/68 (32%), Positives = 27/68 (39%), Gaps = 10/68 (14%)
Query: 57 QPPQPPPGPASASGP-GAAGPASSPPPAGPGPGPALPAVRLSLVRLGEPDSAGAGEPPAT 115
Q P+ PG GP GA+GPA P GP +P GE +AG P
Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP---------GERGAAGIAGPKGD 697
Query: 116 PAGLGSGG 123
+G G
Sbjct: 698 RGDVGEKG 705
Score = 31.2 bits (69), Expect = 3.3
Identities = 54/216 (25%), Positives = 64/216 (29%), Gaps = 43/216 (19%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSPLPKAGSITYRFGSAGQDTQFCLWDLTEDVL 450
GA G R + E P G G P P G + + + +
Sbjct: 75 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 134
Query: 451 YPHPPLARTRTLPGTPGTTPPAASSSRGGEPG-------------PGPLPRSLSRSNSLP 497
P P R PG G P GEPG PGP P
Sbjct: 135 GPMGP----RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-PGKPGDDGEAG 189
Query: 498 HPAGGGKAGGPGVAAEPGTPFSIGRFATLTLQERRDRGAEKEHKRYHSLGNI-----SRG 552
P G+ G PG G P + G K H+ Y L + G
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPG------------LPGVKGHRGYPGLDGAKGEAGAPG 237
Query: 553 GSGGSGSGGEK----PSGP--VP--RSRLDPAKVLG 580
G SGS GE P GP +P R R PA G
Sbjct: 238 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAG 273
Score = 30.8 bits (68), Expect = 4.3
Identities = 25/90 (27%), Positives = 31/90 (34%), Gaps = 10/90 (11%)
Query: 46 GPASAQTPVPPQPPQPP---------PGPASASG-PGAAGPASSPPPAGPGPGPALPAVR 95
GP Q P Q P+ PGP G PG G P P GP P L
Sbjct: 51 GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF 110
Query: 96 LSLVRLGEPDSAGAGEPPATPAGLGSGGDR 125
+ + G + AG + +G G R
Sbjct: 111 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 140
Score = 30.4 bits (67), Expect = 5.6
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 40 GAARRSGPASAQTPVPPQPPQPPPGPASASGP-GAAGPASSPPPAGP-GP 87
GA GP + P P Q G A A GP G +GPA + GP GP
Sbjct: 996 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045
Score = 30.0 bits (66), Expect = 7.3
Identities = 41/136 (30%), Positives = 51/136 (37%), Gaps = 14/136 (10%)
Query: 391 GADGERSGEEEEEEPEAAGTGSAGGAPLSP--LPKAGSITYRFGSAGQDTQFCLWDLTED 448
GA GE + E + G + G P+ P LP T G+AG D
Sbjct: 228 GAKGEAGAPGVKGESGSPGENGSPG-PMGPRGLPGERGRTGPAGAAGARGN----DGQPG 282
Query: 449 VLYPHPPL--ARTRTLPGTPGTTPPAA-SSSRGGEPGPGPLPRSLSRSNSLPHPAGGGKA 505
P P+ A PG PG A + +RG E GP R + P PAG +
Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP--RGEPGTPGSPGPAGA--S 338
Query: 506 GGPGVAAEPGTPFSIG 521
G PG PG S G
Sbjct: 339 GNPGTDGIPGAKGSAG 354
Score = 30.0 bits (66), Expect = 7.3
Identities = 41/149 (27%), Positives = 49/149 (32%), Gaps = 31/149 (20%)
Query: 5 GAEGGSGPGAAMGDCAEIK-SQFRTREGFYKLLPGD-------GAARRSGPASAQTPVPP 56
G +G +GP G E + F+ +G K PG G A G A+
Sbjct: 372 GPQGATGPLGPKGQTGEPGIAGFKGEQG-PKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430
Query: 57 QPPQPPPGPASASG-------PGAAGPASSPPPAGPG-----------PG----PALPAV 94
P PPG A G G AGP +P GP PG P LP
Sbjct: 431 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 490
Query: 95 RLSLVRLGEPDSAGAGEPPATPAGLGSGG 123
R R G+ G P P G G
Sbjct: 491 RGLTGRPGDAGPQGKVGPSGAPGEDGRPG 519
Score = 29.6 bits (65), Expect = 9.5
Identities = 34/98 (34%), Positives = 37/98 (37%), Gaps = 23/98 (23%)
Query: 5 GAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPG-DGAARRSGPASAQ----------TP 53
G G GP G E REG PG DG R G A + P
Sbjct: 948 GPPGPVGPPGLTGPAGE-----PGREGS----PGADGPPGRDGAAGVKGDRGETGAVGAP 998
Query: 54 VPPQPPQPPPGPASASG-PGAAGPASSPPPAGPGPGPA 90
P PP PGPA +G G G A + P GP GPA
Sbjct: 999 GAPGPP-GSPGPAGPTGKQGDRGEAGAQGPMGPS-GPA 1034
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 46 GPASAQTPVPPQPPQPPPGPASASGPGAAGPA-----SSPPPAGPGPGPALPAVRLSLVR 100
GPA A +PP P PPP P ++GP P PPP P P P LPA L
Sbjct: 322 GPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLAS 381
Query: 101 LGE 103
+ E
Sbjct: 382 MSE 384
Score = 43.1 bits (100), Expect = 8e-04
Identities = 26/70 (37%), Positives = 30/70 (42%), Gaps = 21/70 (30%)
Query: 38 GDGAARRSGPASAQTPV--------------PPQPPQPPPGPASASGPGAAGPASSPPPA 83
GD +A G +A P PP PP PPGPA AS + PPP
Sbjct: 282 GDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS-------VALPPPP 334
Query: 84 GPGPGPALPA 93
GP P P LP+
Sbjct: 335 GPPPPPPLPS 344
Score = 33.5 bits (75), Expect = 0.66
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 18/84 (21%)
Query: 45 SGPASAQTP---VPPQPPQPPPGPASASGPGAA--------GPASSPPPAGPGPGPALPA 93
+ PAS +TP V PG +AS P GP + PPP PGPA +
Sbjct: 268 AAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQAS 327
Query: 94 VRLSLVRLGEPDSAGAGEPPATPA 117
V L P G PP P+
Sbjct: 328 VAL-------PPPPGPPPPPPLPS 344
Score = 32.0 bits (71), Expect = 1.9
Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 1/75 (1%)
Query: 36 LPGDGAARRSGPASAQTPVPPQPPQPPPGPASASGPGAAGPASSPPPAGPGPGPALPAVR 95
LP G P VPP PP PP P ASG A + P G A+ +
Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPL-TGLAAAIAGAK 400
Query: 96 LSLVRLGEPDSAGAG 110
L V E S +G
Sbjct: 401 LRKVSRMEDTSFPSG 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,002,893
Number of Sequences: 37866
Number of extensions: 2542840
Number of successful extensions: 55236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1052
Number of HSP's successfully gapped in prelim test: 1611
Number of HSP's that attempted gapping in prelim test: 20406
Number of HSP's gapped (non-prelim): 22035
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.