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Search of human proteins with 62912479
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62912479 major histocompatibility complex, class I, E
precursor [Homo sapiens]
(358 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62912479 major histocompatibility complex, class I, E precurs... 745 0.0
gi|24797067 major histocompatibility complex, class I, A precurs... 583 e-167
gi|17986001 major histocompatibility complex, class I, B precurs... 575 e-164
gi|52630342 major histocompatibility complex, class I, C precurs... 558 e-159
gi|4504415 major histocompatibility complex, class I, G precurso... 549 e-156
gi|149158702 major histocompatibility complex, class I, F isofor... 520 e-148
gi|149158698 major histocompatibility complex, class I, F isofor... 520 e-148
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 482 e-136
gi|149158700 major histocompatibility complex, class I, F isofor... 273 2e-73
gi|4504417 major histocompatibility complex, class I-related [Ho... 225 4e-59
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 201 6e-52
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 188 6e-48
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 184 1e-46
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 178 6e-45
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 155 5e-38
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 144 9e-35
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 144 9e-35
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 142 4e-34
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 141 8e-34
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 138 9e-33
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 110 1e-24
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 110 2e-24
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 100 2e-21
gi|110618224 CD1A antigen precursor [Homo sapiens] 86 7e-17
gi|169168591 PREDICTED: similar to major histocompatibility comp... 72 1e-12
gi|239740920 PREDICTED: similar to major histocompatibility comp... 70 2e-12
gi|239740918 PREDICTED: similar to major histocompatibility comp... 70 2e-12
gi|4504399 major histocompatibility complex, class II, DM beta p... 69 6e-12
gi|24797076 major histocompatibility complex, class II, DP beta ... 67 3e-11
gi|150418002 major histocompatibility complex, class II, DQ beta... 67 3e-11
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 745 bits (1923), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND
Sbjct: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH
Sbjct: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY
Sbjct: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ
Sbjct: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ
Sbjct: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL 358
PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL
Sbjct: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL 358
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 583 bits (1504), Expect = e-167
Identities = 279/354 (78%), Positives = 314/354 (88%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
M TLLLLLS ALALTQTWAGSHS++YF TSVSRPGRGEPRFI+VGYVDDTQFVRFD+D
Sbjct: 4 MAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD 63
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
AAS RM PRAPW+EQEG EYWD+ETR+ + +Q RV+L TLRGYYNQSEAGSHT+Q M+
Sbjct: 64 AASQRMEPRAPWIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMY 123
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GC++G DGRFLRGY Q AYDGKDY+ LNEDLRSWTA D AAQI+++K A EAE RAY
Sbjct: 124 GCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAHEAEQLRAY 183
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
L+ TCVEWL +YLE GKETL +PPKTH+THHPISDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
DGE TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP+P+TLRW+ +SQ
Sbjct: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQ 303
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSE 354
PTIPIVGIIAGLVLLG+V++GAVVAAV+WR+KSS KGGSY++A SDSAQGS+
Sbjct: 304 PTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSD 357
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 575 bits (1482), Expect = e-164
Identities = 274/354 (77%), Positives = 310/354 (87%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
M T+LLLLS ALALT+TWAGSHS++YF+TSVSRPGRGEPRFISVGYVDDTQFVRFD+D
Sbjct: 4 MAPRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSD 63
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
AASPR PRAPW+EQEG EYWDR T+ + AQ R +LR LRGYYNQSEAGSHTLQ M+
Sbjct: 64 AASPREEPRAPWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY 123
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GC++GPDGR LRG++Q+AYDGKDY+ LNEDLRSWTA DTAAQI+++K A EAE +RAY
Sbjct: 124 GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAREAEQRRAY 183
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
LE CVEWL +YLE GK+ L +PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
DGE TQDTELVETRPAGD TFQKWAAVVVPSGEEQRYTCHVQHEGLP+P+TLRW+P+SQ
Sbjct: 244 DGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQ 303
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSE 354
T+PIVGI+AGL +L VV GAVVAAV+ R+KSSGGKGGSYS+A SDSAQGS+
Sbjct: 304 STVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDSAQGSD 357
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 558 bits (1437), Expect = e-159
Identities = 271/355 (76%), Positives = 303/355 (85%), Gaps = 1/355 (0%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
M LLLLLS LALT+TWA SHS++YF T+VSRPGRGEPRFISVGYVDDTQFVRFD+D
Sbjct: 4 MAPRALLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVRFDSD 63
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
AASPR PRAPW+EQEG EYWDRET+ + AQ RV+LR LRGYYNQSE GSHTLQ M
Sbjct: 64 AASPRGEPRAPWVEQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHTLQRMS 123
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GC+LGPDGR LRGY+Q AYDGKDY+ LNEDLRSWTA DTAAQI+++K A AE RAY
Sbjct: 124 GCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARAAEQLRAY 183
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
LE TCVEWL +YLE GKETL EPPKTHVTHHP+SDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 184 LEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEITLTWQR 243
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
DGE TQDTELVETRPAGDGTFQKWAAVVVPSG+EQRYTCH+QHEGL EP+TL W+P+SQ
Sbjct: 244 DGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWEPSSQ 303
Query: 301 PTIPIVGIIAGL-VLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQGSE 354
PTIPI+GI+AGL VL+ V GAVV A++ R+KSSGGKGGS S+A S+SAQGS+
Sbjct: 304 PTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSNSAQGSD 358
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 549 bits (1415), Expect = e-156
Identities = 257/334 (76%), Positives = 290/334 (86%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
M TL LLLS AL LT+TWAGSHS++YF +VSRPGRGEPRFI++GYVDDTQFVRFD+D
Sbjct: 4 MAPRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSD 63
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
+A PRM PRAPW+EQEG EYW+ ETR+ + AQ R+NL+TLRGYYNQSEA SHTLQWM
Sbjct: 64 SACPRMEPRAPWVEQEGPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMI 123
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GC+LG DGR LRGYEQ+AYDGKDYL LNEDLRSWTA DTAAQIS++K A+ AE +RAY
Sbjct: 124 GCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAEQRRAY 183
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
LE TCVEWLH+YLE GKE L +PPKTHVTHHP+ D+EATLRCWALGFYPAEI LTWQ+
Sbjct: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
DGE TQD ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP+ LRWK +S
Sbjct: 244 DGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSSL 303
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSS 334
PTIPI+GI+AGLV+L +VV+GA VAAV+WRKKSS
Sbjct: 304 PTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 520 bits (1340), Expect = e-148
Identities = 251/344 (72%), Positives = 284/344 (82%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
M +LLLLLS ALALT TWAGSHSL+YF T+VSRPGRGEPR+I+V YVDDTQF+RFD+D
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
AA PRM PR PW+EQEG +YW+ T A+ AQ RV LR L YNQSEAGSHTLQ M+
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GC++GPDGR LRGY Q AYDGKDY++LNEDLRSWTA DT AQI+++ AE R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
LE C+E L +YLE GKETL +PPK HV HHPISDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
DGE TQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+P+ LRW+ + Q
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKA 344
PTIPIVGI+AGLV+LG+VV+GAVVAAV+WRKKSS GSYS+A
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQA 344
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 520 bits (1340), Expect = e-148
Identities = 251/344 (72%), Positives = 284/344 (82%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
M +LLLLLS ALALT TWAGSHSL+YF T+VSRPGRGEPR+I+V YVDDTQF+RFD+D
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
AA PRM PR PW+EQEG +YW+ T A+ AQ RV LR L YNQSEAGSHTLQ M+
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GC++GPDGR LRGY Q AYDGKDY++LNEDLRSWTA DT AQI+++ AE R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
LE C+E L +YLE GKETL +PPK HV HHPISDHEATLRCWALGFYPAEITLTWQ+
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
DGE TQDTELVETRPAGDGTFQKWAAVVVP GEEQRYTCHVQHEGLP+P+ LRW+ + Q
Sbjct: 241 DGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQ 300
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKA 344
PTIPIVGI+AGLV+LG+VV+GAVVAAV+WRKKSS GSYS+A
Sbjct: 301 PTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQA 344
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 482 bits (1240), Expect = e-136
Identities = 231/317 (72%), Positives = 262/317 (82%), Gaps = 4/317 (1%)
Query: 22 GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQEGSEYW 81
GSHSL+YF+T+VSRPG GEPRFISVGYVDDTQFVRFD+D+A+PR PRAPWMEQEG EYW
Sbjct: 38 GSHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQEGPEYW 97
Query: 82 DRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDG 141
D +TR +DTAQ FRV L TLRGYYNQSEAGSHTLQ M+GC++GPDGRFLRG+ Q AYDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 142 KDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLL 201
+DY+ LNEDLRSWTA DTAAQI+++K A AE QR YLE CVE L +YLE GK+ LL
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQRNYLEGRCVEGLRRYLETGKDALL 217
Query: 202 HLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGT 261
+PPK HVTHHPIS+ E TLRCWALGFYP EI+LTWQ++GE TQD ELVETRP+GDGT
Sbjct: 218 RADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGT 277
Query: 262 FQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSG 321
FQKWAA+VVPSGEEQRYTC VQHEGL EP+TLRW+P Q + I+GII GLVLL V
Sbjct: 278 FQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPP-QTSFLIMGIIVGLVLL---VVA 333
Query: 322 AVVAAVIWRKKSSGGKG 338
V AVIWRKK SG +G
Sbjct: 334 LVAGAVIWRKKRSGREG 350
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 273 bits (698), Expect = 2e-73
Identities = 135/204 (66%), Positives = 156/204 (76%)
Query: 1 MVDGTLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDND 60
M +LLLLLS ALALT TWAGSHSL+YF T+VSRPGRGEPR+I+V YVDDTQF+RFD+D
Sbjct: 1 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSD 60
Query: 61 AASPRMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
AA PRM PR PW+EQEG +YW+ T A+ AQ RV LR L YNQSEAGSHTLQ M+
Sbjct: 61 AAIPRMEPREPWVEQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMN 120
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GC++GPDGR LRGY Q AYDGKDY++LNEDLRSWTA DT AQI+++ AE R Y
Sbjct: 121 GCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEFRTY 180
Query: 181 LEDTCVEWLHKYLEKGKETLLHLE 204
LE C+E L +YLE GKETL E
Sbjct: 181 LEGECLELLRRYLENGKETLQRAE 204
Score = 72.4 bits (176), Expect = 6e-13
Identities = 36/51 (70%), Positives = 44/51 (86%)
Query: 294 RWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKA 344
R + + QPTIPIVGI+AGLV+LG+VV+GAVVAAV+WRKKSS GSYS+A
Sbjct: 202 RAEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQA 252
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 225 bits (574), Expect = 4e-59
Identities = 130/338 (38%), Positives = 190/338 (56%), Gaps = 13/338 (3%)
Query: 7 LLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRM 66
LL L L + + + +HSL+YF VS P G P FISVGYVD +D+ + +
Sbjct: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS--VTRQK 65
Query: 67 VPRAPWM-EQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCELG 125
PRAPWM E ++W+R T+ R Q+F+V L+ L+ +YN S GSHT Q M GCEL
Sbjct: 66 EPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS--GSHTYQRMIGCELL 123
Query: 126 PDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLEDT 184
DG G+ Q+AYDG+D+L N+D SW AVD A +Q + E +Q+ +LE+
Sbjct: 124 EDGS-TTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEE 182
Query: 185 CVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEG 244
C+ WL ++LE GK+TL EPP V L C A GFYP EI +TW ++GE
Sbjct: 183 CIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEE 242
Query: 245 HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIP 304
Q+ + + P+GDGT+Q WA++ + Y+CHV+H G+ + + P TIP
Sbjct: 243 IVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQV---PQESETIP 299
Query: 305 IV-GIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSY 341
+V ++G ++L V++G V ++WR++ G Y
Sbjct: 300 LVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIY 335
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 201 bits (512), Expect = 6e-52
Identities = 120/343 (34%), Positives = 184/343 (53%), Gaps = 9/343 (2%)
Query: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65
LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R
Sbjct: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
Query: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCEL 124
+ PR PW+ S+ W + ++S + +F V+ T+ +N S+ SHTLQ + GCE+
Sbjct: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEM 126
Query: 125 GPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLED 183
D GY ++ YDG+D+L D W A + A ++ + A RAYLE
Sbjct: 127 QEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLER 185
Query: 184 TCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGE 243
C L + LE G+ L PP VTHH ++ TLRC AL +YP IT+ W +D +
Sbjct: 186 DCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQ 244
Query: 244 G-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT 302
++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P+ + W+P+ T
Sbjct: 245 PMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGT 304
Query: 303 IPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 305 L-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 346
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 188 bits (478), Expect = 6e-48
Identities = 108/307 (35%), Positives = 170/307 (55%), Gaps = 9/307 (2%)
Query: 42 RFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLR 100
R + +GYVDD FV +D++ S R+ PR PW+ S+ W + ++S + +F V+
Sbjct: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
Query: 101 TLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTA 160
T+ +N S+ SHTLQ + GCE+ D GY ++ YDG+D+L D W A +
Sbjct: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
Query: 161 AQISEQK-SNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHE 219
A ++ + A RAYLE C L + LE G+ L PP VTHH ++
Sbjct: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
Query: 220 ATLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY 278
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRY
Sbjct: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
Query: 279 TCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKG 338
TC V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G
Sbjct: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
Query: 339 GSYSKAE 345
G Y AE
Sbjct: 317 GHYVLAE 323
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 184 bits (467), Expect = 1e-46
Identities = 114/343 (33%), Positives = 176/343 (51%), Gaps = 23/343 (6%)
Query: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65
LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R
Sbjct: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
Query: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCEL 124
+ PR PW+ S+ W + ++S + +F V+ T+ +N S+ SHTLQ + GCE+
Sbjct: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEM 126
Query: 125 GPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLED 183
D GY ++ YDG+D+L D W A + A ++ + A RAYLE
Sbjct: 127 QEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLER 185
Query: 184 TCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGE 243
C L + LE G+ L TLRC AL +YP IT+ W +D +
Sbjct: 186 DCPAQLQQLLELGRGVL---------------DQQVTTLRCRALNYYPQNITMKWLKDKQ 230
Query: 244 G-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT 302
++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P+ + W+P+ T
Sbjct: 231 PMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGT 290
Query: 303 IPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 291 L-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 332
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 178 bits (452), Expect = 6e-45
Identities = 102/294 (34%), Positives = 158/294 (53%), Gaps = 9/294 (3%)
Query: 5 TLLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASP 64
+LLLLL A+ + G +SL Y +T +S+ P F ++G ++D QF R+++
Sbjct: 10 SLLLLLGPAVP-QENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYNSKDRKS 68
Query: 65 RMVPRAPWMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCEL 124
+ P W + EG E W ++++ + IF L+ + YYN S GSH LQ GCE+
Sbjct: 69 Q--PMGLWRQVEGMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSN-GSHVLQGRFGCEI 125
Query: 125 GPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLED 183
+ R + ++ YDGKDY+ N+++ +W D AAQI++QK + + +AYLE+
Sbjct: 126 -ENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAYLEE 184
Query: 184 TCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGE 243
C L KYL+ K L +PP VT H + L+C A FYP +I + W + GE
Sbjct: 185 ECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTRAGE 244
Query: 244 GHTQDTEL-VETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWK 296
Q+ EL + G+GT+Q W V VP + Y+CHVQH L +P+ + W+
Sbjct: 245 --VQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 155 bits (392), Expect = 5e-38
Identities = 85/235 (36%), Positives = 130/235 (55%), Gaps = 5/235 (2%)
Query: 113 SHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDA 171
SHTLQ + GCE+ D GY ++ YDG+D+L D W A + A ++ +
Sbjct: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 172 SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYP 231
A RAYLE C L + LE G+ L PP VTHH ++ TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYP 144
Query: 232 AEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 290
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 145 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 204
Query: 291 VTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 205 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 258
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 144 bits (364), Expect = 9e-35
Identities = 103/335 (30%), Positives = 167/335 (49%), Gaps = 22/335 (6%)
Query: 4 GTLLLLLSEALALTQTWAGSH-SLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAA 62
G LL LL +L A SH SL Y T+VS P G P F G++ Q++ +++
Sbjct: 12 GLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG 66
Query: 63 SPRMVPRAPWM-EQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG 121
P W+ E + S YW++ET R ++F + L G G +TLQ + G
Sbjct: 67 EAE--PCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLG 118
Query: 122 CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAV-DTAAQISEQKSNDASEAEHQRAY 180
CELGPD + +FA +G++++ + +W A IS++ A + +
Sbjct: 119 CELGPDNTSVPT-AKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
L +C L ++LE+G+ L EPP + P S + L C A FYP E+ L + +
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
+G T + P DG+F +++ V SG+E Y C VQH GL +P+ + + ++
Sbjct: 238 NGLA--AGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSG 335
++ +VGI+ G++LL + AV A++WR+ SG
Sbjct: 296 SSVLVVGIVIGVLLL---TAAAVGGALLWRRMRSG 327
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 144 bits (364), Expect = 9e-35
Identities = 103/335 (30%), Positives = 167/335 (49%), Gaps = 22/335 (6%)
Query: 4 GTLLLLLSEALALTQTWAGSH-SLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAA 62
G LL LL +L A SH SL Y T+VS P G P F G++ Q++ +++
Sbjct: 12 GLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRG 66
Query: 63 SPRMVPRAPWM-EQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG 121
P W+ E + S YW++ET R ++F + L G G +TLQ + G
Sbjct: 67 EAE--PCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------KGPYTLQGLLG 118
Query: 122 CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAV-DTAAQISEQKSNDASEAEHQRAY 180
CELGPD + +FA +G++++ + +W A IS++ A + +
Sbjct: 119 CELGPDNTSVPT-AKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTF 177
Query: 181 LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQ 240
L +C L ++LE+G+ L EPP + P S + L C A FYP E+ L + +
Sbjct: 178 LLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLR 237
Query: 241 DGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQ 300
+G T + P DG+F +++ V SG+E Y C VQH GL +P+ + + ++
Sbjct: 238 NGLA--AGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAK 295
Query: 301 PTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSG 335
++ +VGI+ G++LL + AV A++WR+ SG
Sbjct: 296 SSVLVVGIVIGVLLL---TAAAVGGALLWRRMRSG 327
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 142 bits (359), Expect = 4e-34
Identities = 93/293 (31%), Positives = 144/293 (49%), Gaps = 18/293 (6%)
Query: 4 GTLLLLLSEALALTQTWAGS--HSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDA 61
G + LLL+ A + HSL+Y T +S G + F++ ++D F+R D
Sbjct: 4 GPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQK 63
Query: 62 ASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
R P+ W E G++ WDRETR + R+ L ++ + G H+LQ +
Sbjct: 64 C--RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIK----DQKEGLHSLQEIR 117
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT------AVDTAAQISEQKSNDASEA 174
CE+ D R + F YDG+ +L+ N + + WT A A + DA +
Sbjct: 118 VCEIHEDNS-TRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKT 176
Query: 175 EHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEI 234
+ + C++ L +YL+ G L PP +VT S+ T+ C A GFYP I
Sbjct: 177 KTHYHAMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNI 235
Query: 235 TLTWQQDGEGHTQDT-ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 286
TL+W+QDG + DT + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 236 TLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSG 288
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 141 bits (356), Expect = 8e-34
Identities = 94/293 (32%), Positives = 148/293 (50%), Gaps = 18/293 (6%)
Query: 4 GTLLLLLSEALALTQTWAGS--HSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDA 61
G +LL L+ A A + HSL+Y +S+ G + F++ G++D F+R+D
Sbjct: 4 GRVLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQK 63
Query: 62 ASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH 120
R P+ W E G++ WD ET + Q R RTL +Q + G H+LQ +
Sbjct: 64 R--RAKPQGQWAENVLGAKTWDTETEDLTENGQDLR---RTLTHIKDQ-KGGLHSLQEIR 117
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWT------AVDTAAQISEQKSNDASEA 174
CE+ D RG F YDG+ +L+ N + + T A A ++ DA +
Sbjct: 118 VCEIHEDSS-TRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKT 176
Query: 175 EHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEI 234
+ ++ C++ L +YL+ G + PP +VT +S+ T+ C A FYP I
Sbjct: 177 KTHYRAMQADCLQKLQRYLKSGV-AIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNI 235
Query: 235 TLTWQQDGEGHTQDT-ELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 286
TLTW+QDG + +T + + P G+GT+Q W A + GEEQR+TC+++H G
Sbjct: 236 TLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSG 288
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 138 bits (347), Expect = 9e-33
Identities = 79/235 (33%), Positives = 122/235 (51%), Gaps = 19/235 (8%)
Query: 113 SHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDA 171
SHTLQ + GCE+ D GY ++ YDG+D+L D W A + A ++ +
Sbjct: 27 SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 172 SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYP 231
A RAYLE C L + LE G+ L TLRC AL +YP
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVL---------------DQQVTTLRCRALNYYP 130
Query: 232 AEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEP 290
IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P
Sbjct: 131 QNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQP 190
Query: 291 VTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 191 LIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 244
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 110 bits (276), Expect = 1e-24
Identities = 54/144 (37%), Positives = 87/144 (60%), Gaps = 3/144 (2%)
Query: 203 LEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGT 261
L PP VTHH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT
Sbjct: 25 LLPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 83
Query: 262 FQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSG 321
+Q W + VP GEEQRYTC V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++
Sbjct: 84 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFI 142
Query: 322 AVVAAVIWRKKSSGGKGGSYSKAE 345
++ ++ +++ S G G Y AE
Sbjct: 143 GILFIILRKRQGSRGAMGHYVLAE 166
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 110 bits (275), Expect = 2e-24
Identities = 53/142 (37%), Positives = 86/142 (60%), Gaps = 3/142 (2%)
Query: 205 PPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQ 263
PP VTHH ++ TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q
Sbjct: 115 PPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 173
Query: 264 KWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAV 323
W + VP GEEQRYTC V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++ +
Sbjct: 174 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGI 232
Query: 324 VAAVIWRKKSSGGKGGSYSKAE 345
+ ++ +++ S G G Y AE
Sbjct: 233 LFIILRKRQGSRGAMGHYVLAE 254
Score = 55.8 bits (133), Expect = 6e-08
Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65
LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R
Sbjct: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
Query: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSE 110
+ PR PW+ S+ W + ++S + +F V+ T+ +N S+
Sbjct: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 100 bits (250), Expect = 2e-21
Identities = 47/126 (37%), Positives = 78/126 (61%), Gaps = 2/126 (1%)
Query: 221 TLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYT 279
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRYT
Sbjct: 116 TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYT 175
Query: 280 CHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGG 339
C V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G G
Sbjct: 176 CQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 234
Query: 340 SYSKAE 345
Y AE
Sbjct: 235 HYVLAE 240
Score = 55.8 bits (133), Expect = 6e-08
Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 3/106 (2%)
Query: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65
LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R
Sbjct: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
Query: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSE 110
+ PR PW+ S+ W + ++S + +F V+ T+ +N S+
Sbjct: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 85.5 bits (210), Expect = 7e-17
Identities = 83/321 (25%), Positives = 141/321 (43%), Gaps = 42/321 (13%)
Query: 10 LSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPR 69
L E L+ TW S Y H+ + +S G++ D Q +D+++++ +V
Sbjct: 21 LKEPLSFHVTWIASF---YNHS-------WKQNLVS-GWLSDLQTHTWDSNSST--IVFL 67
Query: 70 APWMEQEGS-EYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMH-------- 120
PW S E W ++ +FR+ RT+R + +H LQ+ +
Sbjct: 68 CPWSRGNFSNEEW-------KELETLFRI--RTIRSFEGIRRY-AHELQFEYPFEIQVTG 117
Query: 121 GCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEAEHQRAY 180
GCEL G+ + Q AY G D+++ + SW A +++ ++ +H+
Sbjct: 118 GCELH-SGKVSGSFLQLAYQGSDFVSFQNN--SWLPYPVAGNMAKHFCKVLNQNQHENDI 174
Query: 181 ----LEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPI-SDHEATLRCWALGFYPAEIT 235
L DTC ++ L+ GK L P+ ++H P L C GFYP +
Sbjct: 175 THNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVW 234
Query: 236 LTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP-EPVTLR 294
+ W + GE Q T+ + P+ DGT+ A + V +GE +C V+H L + + L
Sbjct: 235 VMWMR-GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLY 293
Query: 295 WKPASQPTIPIVGIIAGLVLL 315
W+ S I+ +I L+LL
Sbjct: 294 WEHHSSVGFIILAVIVPLLLL 314
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 71.6 bits (174), Expect = 1e-12
Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 131 LRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEA-EHQRAYLEDTCVEWL 189
+RG ++ Y+ ++Y + D+ + AV + + N E E RA ++ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVC---R 112
Query: 190 HKY-------LEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDG 242
H Y L++ E + + P +T +H L C FYPA+I + W ++
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPAQIKVRWFRND 167
Query: 243 EGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT 302
+ T GD TFQ + + YTCHV+H L P+T+ W+ S+
Sbjct: 168 QEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESA 227
Query: 303 -----IPIVGIIAGLVLLG 316
I G + GL+ LG
Sbjct: 228 QSKMLSGIGGFVLGLIFLG 246
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 70.5 bits (171), Expect = 2e-12
Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 21/199 (10%)
Query: 131 LRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEA-EHQRAYLEDTCVEWL 189
+RG ++ Y+ ++Y + D+ + AV + + N E E RA L+ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVC---R 112
Query: 190 HKY-------LEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDG 242
H Y L++ E + + P +T +H L C FYPA+I + W ++
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPAQIKVRWFRND 167
Query: 243 EGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT 302
+ T GD TFQ + + YTCHV+H L P+ + W+ S+
Sbjct: 168 QEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESA 227
Query: 303 -----IPIVGIIAGLVLLG 316
I G + GL+ LG
Sbjct: 228 QSKMLSGIGGFVLGLIFLG 246
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 70.5 bits (171), Expect = 2e-12
Identities = 51/199 (25%), Positives = 83/199 (41%), Gaps = 21/199 (10%)
Query: 131 LRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEA-EHQRAYLEDTCVEWL 189
+RG ++ Y+ ++Y + D+ + AV + + N E E RA L+ C
Sbjct: 56 VRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVC---R 112
Query: 190 HKY-------LEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDG 242
H Y L++ E + + P +T +H L C FYPA+I + W ++
Sbjct: 113 HNYQLELRTTLQRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPAQIKVRWFRND 167
Query: 243 EGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT 302
+ T GD TFQ + + YTCHV+H L P+ + W+ S+
Sbjct: 168 QEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESA 227
Query: 303 -----IPIVGIIAGLVLLG 316
I G + GL+ LG
Sbjct: 228 QSKMLSGIGGFVLGLIFLG 246
>gi|4504399 major histocompatibility complex, class II, DM beta
precursor [Homo sapiens]
Length = 263
Score = 68.9 bits (167), Expect = 6e-12
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 10/152 (6%)
Query: 205 PPKTHVTHH-PISDHEAT-LRCWALGFYPAEITLTWQQDGEGHTQDTELVET-RPAGDGT 261
PP V P + E L C+ GFYPAE+T+TW+++G+ + +T +P GD T
Sbjct: 114 PPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNGDWT 173
Query: 262 FQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPI-VGIIAGLVLLGSVVS 320
+Q + + + YTC V+H G PEP+ W P P + V + A + LG ++
Sbjct: 174 YQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLKVSVSAVTLGLGLIIF 233
Query: 321 GAVVAAVIWRKKSSGGKGGSYSKAEWSDSAQG 352
+ + WR+ SY+ S+ ++G
Sbjct: 234 S--LGVISWRRAGH----SSYTPLPGSNYSEG 259
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 66.6 bits (161), Expect = 3e-11
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 8/194 (4%)
Query: 132 RGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEA-EHQRAYLEDTCVEWLH 190
R E++ Y+ +++ + D+ + AV + + + N + E +RA + C H
Sbjct: 52 RFLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMC---RH 108
Query: 191 KYLEKGKETLLHLEPPKTHVTHH---PISDHEATLRCWALGFYPAEITLTWQQDGEGHTQ 247
Y G TL P+ +V+ P+ H L C FYP I + W +G+ T
Sbjct: 109 NYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNL-LVCHVTDFYPGSIQVRWFLNGQEETA 167
Query: 248 DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPTIPIVG 307
GD TFQ + + + YTC V+H L PVT+ WK S
Sbjct: 168 GVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTL 227
Query: 308 IIAGLVLLGSVVSG 321
AG +LG ++ G
Sbjct: 228 TGAGGFVLGLIICG 241
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 66.6 bits (161), Expect = 3e-11
Identities = 48/194 (24%), Positives = 80/194 (41%), Gaps = 21/194 (10%)
Query: 136 QFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDASEA-EHQRAYLEDTCVEWLHKY-- 192
++ Y+ ++Y + D+ + AV + + N E E RA L+ C H Y
Sbjct: 61 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVC---RHNYEV 117
Query: 193 -----LEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGEGHTQ 247
L++ E + + P +T +H L C FYP +I + W ++ + T
Sbjct: 118 AFRGILQRRVEPTVTISPSRTEALNH-----HNLLVCSVTDFYPGQIKVRWFRNDQEETA 172
Query: 248 DTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT----- 302
GD TFQ + + YTCHV+H L P+T+ W+ S+
Sbjct: 173 GVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKML 232
Query: 303 IPIVGIIAGLVLLG 316
+ G + GL+ LG
Sbjct: 233 SGVGGFVLGLIFLG 246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,536,696
Number of Sequences: 37866
Number of extensions: 753438
Number of successful extensions: 2136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 1909
Number of HSP's gapped (non-prelim): 185
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.