BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62243290 insulin-like growth factor binding protein 4 precursor [Homo sapiens] (258 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62243290 insulin-like growth factor binding protein 4 precurs... 559 e-160 gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 180 1e-45 gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 177 8e-45 gi|62243068 insulin-like growth factor binding protein 3 isoform... 152 2e-37 gi|62243248 insulin-like growth factor binding protein 3 isoform... 152 4e-37 gi|4504615 insulin-like growth factor binding protein 1 precurso... 144 6e-35 gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 124 1e-28 gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 52 7e-07 gi|144953895 nidogen 2 precursor [Homo sapiens] 50 1e-06 gi|208022668 endothelial cell-specific molecule 1 isoform b prec... 48 7e-06 gi|5901946 endothelial cell-specific molecule 1 isoform a precur... 48 1e-05 gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 46 4e-05 gi|56090548 insulin-like growth factor binding protein-like 1 [H... 44 1e-04 gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 44 1e-04 gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 44 2e-04 gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 43 3e-04 gi|115298674 nidogen 1 precursor [Homo sapiens] 43 3e-04 gi|93141003 testican 3 isoform 1 [Homo sapiens] 42 4e-04 gi|93141001 testican 3 isoform 2 [Homo sapiens] 42 4e-04 gi|55770862 thyroglobulin [Homo sapiens] 42 7e-04 gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 42 7e-04 gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 42 7e-04 gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 39 0.003 gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] 39 0.004 gi|4503123 connective tissue growth factor [Homo sapiens] 38 0.008 gi|68448544 CD74 antigen isoform a [Homo sapiens] 38 0.008 gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 37 0.017 gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 36 0.038 gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 35 0.050 gi|13128860 histone deacetylase 1 [Homo sapiens] 33 0.32 >gi|62243290 insulin-like growth factor binding protein 4 precursor [Homo sapiens] Length = 258 Score = 559 bits (1441), Expect = e-160 Identities = 258/258 (100%), Positives = 258/258 (100%) Query: 1 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA 60 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA Sbjct: 1 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA 60 Query: 61 LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE 120 LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE Sbjct: 61 LGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDE 120 Query: 121 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR 180 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR Sbjct: 121 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR 180 Query: 181 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG 240 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG Sbjct: 181 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG 240 Query: 241 LEPKGELDCHQLADSFRE 258 LEPKGELDCHQLADSFRE Sbjct: 241 LEPKGELDCHQLADSFRE 258 >gi|10834982 insulin-like growth factor binding protein 5 [Homo sapiens] Length = 272 Score = 180 bits (457), Expect = 1e-45 Identities = 109/275 (39%), Positives = 142/275 (51%), Gaps = 26/275 (9%) Query: 1 MLPLCLVAALLLA-AGPGPSLGDEAIHCPPCSEEKLARCRP-PVGCEELVREPGCGCCAT 58 M+ L V LL A AGP SLG +HC PC E+ L+ C P P+GCE LV+EPGCGCC T Sbjct: 1 MVLLTAVLLLLAAYAGPAQSLGS-FVHCEPCDEKALSMCPPSPLGCE-LVKEPGCGCCMT 58 Query: 59 CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCME----LAEIEAIQESLQ 114 CAL G CGVYT RC GLRC P + EKPLH L+HG+GVC+ +++ ++S + Sbjct: 59 CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSRE 118 Query: 115 PSDKDEGDHPNNSFSP---CSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARP--- 168 + + ++SP H R K A +DR + K G A P Sbjct: 119 HEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRII 178 Query: 169 --------VPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALD 220 QG C+ + +L+ L AS +Y +PNCDR G + KQC P+ Sbjct: 179 SAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVY---LPNCDRKGFYKRKQCKPSRG 235 Query: 221 GQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADS 255 +RG CWCVD K G+KLPG G+ CH S Sbjct: 236 RKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFDSS 269 >gi|55925576 insulin-like growth factor binding protein 2, 36kDa [Homo sapiens] Length = 328 Score = 177 bits (449), Expect = 8e-45 Identities = 112/294 (38%), Positives = 150/294 (51%), Gaps = 44/294 (14%) Query: 1 MLPLCLVAALLLAA--GPGPSLGDEAIHCPPCSEEKLARCRPP----------------V 42 +LPL + LLL A G G + + CPPC+ E+LA C PP + Sbjct: 17 LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76 Query: 43 GCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCME 102 C ELVREPGCGCC+ CA G CGVYTPRCG GLRCYP G E PL L+ G+G C + Sbjct: 77 PCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEK 136 Query: 103 L--AEIEAIQESLQPS--DKDEG-------DHPNNSFSPCSAHDRRCLQ---KHFAKIRD 148 AE A E + + D EG D N + R+ L+ K A R+ Sbjct: 137 RRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFRE 196 Query: 149 RST-------SGGKMKVNGAPREDARPVP-QGSCQSELHRALERLAA----SQSRTHEDL 196 + T GGK + + RP P + CQ EL + LER++ + E L Sbjct: 197 KVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHL 256 Query: 197 YIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCH 250 Y + IPNCD++G ++ KQC +L+GQRG+CWCV+ TG + G +G+ +CH Sbjct: 257 YSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECH 310 >gi|62243068 insulin-like growth factor binding protein 3 isoform b precursor [Homo sapiens] Length = 291 Score = 152 bits (385), Expect = 2e-37 Identities = 92/264 (34%), Positives = 124/264 (46%), Gaps = 36/264 (13%) Query: 13 AAGPGPSLGDEAIHCPPCSEEKLARCRPPVG-CEELVREPGCGCCATCALGLGMPCGVYT 71 +AG GP + C PC LA+C PP C ELVREPGCGCC TCAL G PCG+YT Sbjct: 31 SAGLGP-----VVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYT 85 Query: 72 PRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQP--------SDKDEGDH 123 RCGSGLRC P +PL L+ G+G+C+ + + ++ L P S+ +E Sbjct: 86 ERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRS 145 Query: 124 PNNSFSPCSAHDRRCLQKHFAKIRDR--------STSGGKMKVN---------GAPREDA 166 + SP + R F + + + + KV+ E Sbjct: 146 AGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESK 205 Query: 167 RPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKC 226 R G C+ E+ L L + ++ IPNCD+ G + KQC P+ +RG C Sbjct: 206 RETEYGPCRREMEDTLNHLKFLNVLSPRGVH---IPNCDKKGFYKKKQCRPSKGRKRGFC 262 Query: 227 WCVDRKTGVKLPGGLEPKGELDCH 250 WCVD K G LP G KG+ D H Sbjct: 263 WCVD-KYGQPLP-GYTTKGKEDVH 284 >gi|62243248 insulin-like growth factor binding protein 3 isoform a precursor [Homo sapiens] Length = 297 Score = 152 bits (383), Expect = 4e-37 Identities = 93/270 (34%), Positives = 121/270 (44%), Gaps = 42/270 (15%) Query: 13 AAGPGPSLGDEAIHCPPCSEEKLARCRPPVG-CEELVREPGCGCCATCALGLGMPCGVYT 71 +AG GP + C PC LA+C PP C ELVREPGCGCC TCAL G PCG+YT Sbjct: 31 SAGLGP-----VVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYT 85 Query: 72 PRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPC 131 RCGSGLRC P +PL L+ G+G+C+ + + ++ L P+ G+ P + Sbjct: 86 ERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGEPPAPGNASE 145 Query: 132 SAHDRRC----------------------------LQKHFAKIRDR---STSGGKMKVNG 160 S DR ++K AK R Sbjct: 146 SEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQN 205 Query: 161 APREDARPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALD 220 E R G C+ E+ L L + ++ IPNCD+ G + KQC P+ Sbjct: 206 FSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVH---IPNCDKKGFYKKKQCRPSKG 262 Query: 221 GQRGKCWCVDRKTGVKLPGGLEPKGELDCH 250 +RG CWCVD K G LP G KG+ D H Sbjct: 263 RKRGFCWCVD-KYGQPLP-GYTTKGKEDVH 290 >gi|4504615 insulin-like growth factor binding protein 1 precursor [Homo sapiens] Length = 259 Score = 144 bits (364), Expect = 6e-35 Identities = 86/249 (34%), Positives = 126/249 (50%), Gaps = 20/249 (8%) Query: 10 LLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVG--CEELVREPGCGCCATCALGLGMPC 67 LLL G + G C PCS EKLA C PPV C E+ R GCGCC CAL LG C Sbjct: 14 LLLTVQVGVTAG-APWQCAPCSAEKLALC-PPVSASCSEVTRSAGCGCCPMCALPLGAAC 71 Query: 68 GVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEA-------IQESLQPSDKDE 120 GV T RC GL C G ++PLH L GQG C++ ++ A ES + ++ E Sbjct: 72 GVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGSPESPESTEITE 131 Query: 121 GDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHR 180 + +N + + + D S + + V + + C+ EL+R Sbjct: 132 EELLDNFHLMAPSEEDHSILWDAISTYDGSKA---LHVTNIKKW------KEPCRIELYR 182 Query: 181 ALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGG 240 +E LA +Q + E++ +PNC++NG +H +QC ++DG+ G CWCV G ++PG Sbjct: 183 VVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGS 242 Query: 241 LEPKGELDC 249 E +G+ +C Sbjct: 243 PEIRGDPNC 251 >gi|11321593 insulin-like growth factor binding protein 6 [Homo sapiens] Length = 240 Score = 124 bits (310), Expect = 1e-28 Identities = 89/251 (35%), Positives = 114/251 (45%), Gaps = 29/251 (11%) Query: 3 PLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGC--EELVREPGCGCCAT-- 58 PL L+ ALLLAA PG +L CP C + A C P GC EE P GC Sbjct: 9 PLLLLLALLLAASPGGALA----RCPGCGQGVQAGC--PGGCVEEEDGGSPAEGCAEAEG 62 Query: 59 CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQPSDK 118 C G CGVYTP C GL+C+PP+ E PL L+ G+G C+ A A+ E K Sbjct: 63 CLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLP-ARAPAVAEENPKESK 121 Query: 119 DEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSEL 178 P + +RR Q R+ TS + N A +D G C+ L Sbjct: 122 -----PQAGTARPQDVNRRDQQ------RNPGTSTTPSQPNSAGVQDTE---MGPCRRHL 167 Query: 179 HRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLP 238 L++L R + LY +PNCD G + +QC + +RG CWCVDR G LP Sbjct: 168 DSVLQQLQTEVYRGAQTLY---VPNCDHRGFYRKRQCRSSQGQRRGPCWCVDR-MGKSLP 223 Query: 239 GGLEPKGELDC 249 G + G C Sbjct: 224 GSPDGNGSSSC 234 >gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] Length = 480 Score = 51.6 bits (122), Expect = 7e-07 Identities = 40/109 (36%), Positives = 45/109 (41%), Gaps = 13/109 (11%) Query: 1 MLPLCLVAALLLAAGPGPSLGDE------AIHCPPCSEEKLARCRP-PVGCEELVREPGC 53 +LPL L LLLAA L A CP E ARC P P CE C Sbjct: 8 LLPLLL---LLLAAPASAQLSRAGRSAPLAAGCPDRCEP--ARCPPQPEHCEGGRARDAC 62 Query: 54 GCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQ-GVCM 101 GCC C G CG+ CG GL+C P GV Q G+C+ Sbjct: 63 GCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCV 111 >gi|144953895 nidogen 2 precursor [Homo sapiens] Length = 1375 Score = 50.4 bits (119), Expect = 1e-06 Identities = 29/77 (37%), Positives = 35/77 (45%), Gaps = 12/77 (15%) Query: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKT 233 C+ + A + A +R H IP CD GNF P QCH G G CWCVD Sbjct: 940 CEQQQRHAQAQYAYPGARFH-------IPQCDEQGNFLPLQCH----GSTGFCWCVD-PD 987 Query: 234 GVKLPGGLEPKGELDCH 250 G ++PG P G H Sbjct: 988 GHEVPGTQTPPGSTPPH 1004 Score = 39.7 bits (91), Expect = 0.003 Identities = 28/109 (25%), Positives = 41/109 (37%), Gaps = 14/109 (12%) Query: 127 SFSPCSAHDRR----CLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHRAL 182 +F P H C+ ++ T G + P + P C+ L Sbjct: 968 NFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICERWRENLL 1027 Query: 183 ERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDR 231 E + +D Y+ P CD G+F P QCH G+ CWCVD+ Sbjct: 1028 EHYGGTP---RDDQYV---PQCDDLGHFIPLQCH----GKSDFCWCVDK 1066 >gi|208022668 endothelial cell-specific molecule 1 isoform b precursor [Homo sapiens] Length = 134 Score = 48.1 bits (113), Expect = 7e-06 Identities = 36/107 (33%), Positives = 48/107 (44%), Gaps = 16/107 (14%) Query: 1 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA 60 +L LV A L+AA + A+ CP + + C+ C+ V + CGCC CA Sbjct: 6 LLTTLLVPAHLVAAWSN----NYAVDCPQHCDS--SECKSSPRCKRTVLDD-CGCCRVCA 58 Query: 61 LGLGMPC-----GVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCME 102 G G C G+ +CG GLRC P G E P G+C E Sbjct: 59 AGRGETCYRTVSGMDGMKCGPGLRCQPSNG-EDPFGEEF---GICKE 101 >gi|5901946 endothelial cell-specific molecule 1 isoform a precursor [Homo sapiens] Length = 184 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 12/90 (13%) Query: 1 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA 60 +L LV A L+AA + A+ CP + + C+ C+ V + CGCC CA Sbjct: 6 LLTTLLVPAHLVAAWSN----NYAVDCPQHCDS--SECKSSPRCKRTVLDD-CGCCRVCA 58 Query: 61 LGLGMPC-----GVYTPRCGSGLRCYPPRG 85 G G C G+ +CG GLRC P G Sbjct: 59 AGRGETCYRTVSGMDGMKCGPGLRCQPSNG 88 >gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] Length = 1036 Score = 45.8 bits (107), Expect = 4e-05 Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 12/83 (14%) Query: 2 LPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCAL 61 L + L+ LLL A G A+ C PC E K C P C + + CGCC TCA Sbjct: 16 LLVSLLGLLLLLARSGT----RALVCLPCDESK---CEEPRNCPGSIVQGVCGCCYTCAS 68 Query: 62 GLGMPC----GVYTPRCGSGLRC 80 C G+Y C GLRC Sbjct: 69 QRNESCGGTFGIY-GTCDRGLRC 90 >gi|56090548 insulin-like growth factor binding protein-like 1 [Homo sapiens] Length = 278 Score = 44.3 bits (103), Expect = 1e-04 Identities = 38/113 (33%), Positives = 43/113 (38%), Gaps = 24/113 (21%) Query: 1 MLPLCLVAALLLAAGPGPSLGDEAI-----HCPPCSEEKLARCRPPVGCEELVREPG--- 52 +LPL L+ L L PSLG + C PC E C P C PG Sbjct: 7 LLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEG---CPAPAPCPA----PGISA 59 Query: 53 ---CGCCATCALGLGMPCGVYT-PRCGSGLRCYPPRGVEKPLHTLMHGQGVCM 101 CGCCA C G CG RCG GL C P G G+C+ Sbjct: 60 LDECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAP-----EGTGLCV 107 >gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] Length = 457 Score = 43.9 bits (102), Expect = 1e-04 Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 10/67 (14%) Query: 173 SCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRK 232 SC E ALE A Q + + IP C G + P QCHP+ G CWCV Sbjct: 226 SCDQEHQSALEE--AKQPKNDN----VVIPECAHGGLYKPVQCHPS----TGYCWCVLVD 275 Query: 233 TGVKLPG 239 TG +PG Sbjct: 276 TGRPIPG 282 Score = 35.4 bits (80), Expect = 0.050 Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 5/59 (8%) Query: 171 QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCV 229 +G+C+ ++ R + +Q + ++ + IP C+ +G + QCH G CWCV Sbjct: 81 RGNCK-DVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCH----SYTGYCWCV 134 >gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 precursor [Homo sapiens] Length = 439 Score = 43.5 bits (101), Expect = 2e-04 Identities = 27/78 (34%), Positives = 42/78 (53%), Gaps = 12/78 (15%) Query: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKT 233 CQ+E++R +++L+ +S L IP C+ G + QCH G G+CWCVD K Sbjct: 313 CQNEMNR-IQKLSKGKS-----LLGAFIPRCNEEGYYKATQCH----GSTGQCWCVD-KY 361 Query: 234 GVKLPGGLEPKGELDCHQ 251 G +L G +G + C + Sbjct: 362 GNELAGS-RKQGAVSCEE 378 >gi|4504619 insulin-like growth factor binding protein 7 [Homo sapiens] Length = 282 Score = 42.7 bits (99), Expect = 3e-04 Identities = 28/78 (35%), Positives = 30/78 (38%), Gaps = 7/78 (8%) Query: 10 LLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGLGMPC-- 67 LLL S D C P S L PP+GC CGCC CA G G PC Sbjct: 18 LLLLPLSSSSSSDTCGPCEPASCPPL----PPLGCLLGETRDACGCCPMCARGEGEPCGG 73 Query: 68 -GVYTPRCGSGLRCYPPR 84 G C G+ C R Sbjct: 74 GGAGRGYCAPGMECVKSR 91 >gi|115298674 nidogen 1 precursor [Homo sapiens] Length = 1247 Score = 42.7 bits (99), Expect = 3e-04 Identities = 16/31 (51%), Positives = 20/31 (64%), Gaps = 4/31 (12%) Query: 201 IPNCDRNGNFHPKQCHPALDGQRGKCWCVDR 231 +P CD +G++ P QCH G G CWCVDR Sbjct: 875 VPECDAHGHYAPTQCH----GSTGYCWCVDR 901 >gi|93141003 testican 3 isoform 1 [Homo sapiens] Length = 433 Score = 42.4 bits (98), Expect = 4e-04 Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 10/58 (17%) Query: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDR 231 CQ+EL +R + L IP CD +G + P QCH G G+CWCVDR Sbjct: 314 CQTELSNIQKRQGVKK------LLGQYIPLCDEDGYYKPTQCH----GSVGQCWCVDR 361 >gi|93141001 testican 3 isoform 2 [Homo sapiens] Length = 436 Score = 42.4 bits (98), Expect = 4e-04 Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 10/58 (17%) Query: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDR 231 CQ+EL +R + L IP CD +G + P QCH G G+CWCVDR Sbjct: 317 CQTELSNIQKRQGVKK------LLGQYIPLCDEDGYYKPTQCH----GSVGQCWCVDR 364 >gi|55770862 thyroglobulin [Homo sapiens] Length = 2768 Score = 41.6 bits (96), Expect = 7e-04 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 5/41 (12%) Query: 201 IPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGL 241 +P CD G++ P QCH G CWCVD K G +PG L Sbjct: 1028 MPQCDAFGSWEPVQCHAG----TGHCWCVDEKGGF-IPGSL 1063 Score = 37.0 bits (84), Expect = 0.017 Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 16/81 (19%) Query: 177 ELHRALERLAASQS--RTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTG 234 +L +E + +SQ+ +T E L++ P+C G++ QC G+CWCV+ G Sbjct: 594 DLGDVMETVLSSQTCEQTPERLFV---PSCTTEGSYEDVQCFS------GECWCVN-SWG 643 Query: 235 VKLPG----GLEPKGELDCHQ 251 +LPG G +P+ DC + Sbjct: 644 KELPGSRVRGGQPRCPTDCEK 664 Score = 35.0 bits (79), Expect = 0.065 Identities = 40/151 (26%), Positives = 63/151 (41%), Gaps = 21/151 (13%) Query: 102 ELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDRRCLQK-HFAKIRDRSTSGGKMKVNG 160 E + + S + + E P + F P CL+ +A+++ ++ G V+ Sbjct: 1078 EKSRTSGLLSSWKQARSQENPSPKDLFVPA------CLETGEYARLQ--ASGAGTWCVDP 1129 Query: 161 APREDARPVPQGSCQS-ELHRALERLAASQSRTHEDLYIIPIPNCD-RNGNFHPKQCHPA 218 A E+ RP S Q L L+ + SR Y+ P C +G F P QC Sbjct: 1130 ASGEELRPGSSSSAQCPSLCNVLK--SGVLSRRVSPGYV---PACRAEDGGFSPVQC--- 1181 Query: 219 LDGQRGKCWCVDRKTGVKLPGGLEPKGELDC 249 D +G CWCV +G ++PG G+ C Sbjct: 1182 -DQAQGSCWCV-MDSGEEVPGTRVTGGQPAC 1210 Score = 34.3 bits (77), Expect = 0.11 Identities = 13/30 (43%), Positives = 17/30 (56%), Gaps = 5/30 (16%) Query: 201 IPNCDRNGNFHPKQCHPALDGQRGKCWCVD 230 +P+C RNG++ QC G CWCVD Sbjct: 316 VPSCRRNGDYQAVQCQ-----TEGPCWCVD 340 Score = 33.5 bits (75), Expect = 0.19 Identities = 13/30 (43%), Positives = 19/30 (63%), Gaps = 4/30 (13%) Query: 201 IPNCDRNGNFHPKQCHPALDGQRGKCWCVD 230 +P C +G++ P QC D Q+ +CWCVD Sbjct: 117 LPQCQDSGDYAPVQC----DVQQVQCWCVD 142 Score = 29.6 bits (65), Expect = 2.7 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 201 IPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDC 249 +P C +G+F QC DG+ CWCV G ++ G +P + C Sbjct: 49 VPQCAEDGSFQTVQCQN--DGR--SCWCVG-ANGSEVLGSRQPGRPVAC 92 Score = 28.9 bits (63), Expect = 4.6 Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 7/39 (17%) Query: 201 IPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPG 239 +P C G+F P QC +C+CVD + G +PG Sbjct: 684 VPACTSEGHFLPVQCF------NSECYCVDAE-GQAIPG 715 >gi|78190498 secreted modular calcium-binding protein 1 isoform 1 [Homo sapiens] Length = 435 Score = 41.6 bits (96), Expect = 7e-04 Identities = 27/67 (40%), Positives = 30/67 (44%), Gaps = 10/67 (14%) Query: 173 SCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRK 232 SC E ALE +Q E I IP C G + P QCH + G CWCV Sbjct: 226 SCDQERQSALEE---AQQNPREG---IVIPECAPGGLYKPVQCHQST----GYCWCVLVD 275 Query: 233 TGVKLPG 239 TG LPG Sbjct: 276 TGRPLPG 282 Score = 34.7 bits (78), Expect = 0.085 Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 11/59 (18%) Query: 171 QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCV 229 Q C+ E +ALE+ Q +P C +G+F QCH G CWCV Sbjct: 92 QSKCRLERAQALEQAKKPQEAVF-------VPECGEDGSFTQVQCHT----YTGYCWCV 139 >gi|11545873 secreted modular calcium-binding protein 1 isoform 2 [Homo sapiens] Length = 434 Score = 41.6 bits (96), Expect = 7e-04 Identities = 27/67 (40%), Positives = 30/67 (44%), Gaps = 10/67 (14%) Query: 173 SCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRK 232 SC E ALE +Q E I IP C G + P QCH + G CWCV Sbjct: 226 SCDQERQSALEE---AQQNPREG---IVIPECAPGGLYKPVQCHQST----GYCWCVLVD 275 Query: 233 TGVKLPG 239 TG LPG Sbjct: 276 TGRPLPG 282 Score = 34.7 bits (78), Expect = 0.085 Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 11/59 (18%) Query: 171 QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCV 229 Q C+ E +ALE+ Q +P C +G+F QCH G CWCV Sbjct: 92 QSKCRLERAQALEQAKKPQEAVF-------VPECGEDGSFTQVQCHT----YTGYCWCV 139 >gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 isoform 2 [Homo sapiens] Length = 424 Score = 39.3 bits (90), Expect = 0.003 Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 12/79 (15%) Query: 174 CQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKT 233 C +EL R + AA + I IP+CD +G + QC D G CWCVD + Sbjct: 313 CLAELERIQIQEAAKKKPG------IFIPSCDEDGYYRKMQC----DQSSGDCWCVD-QL 361 Query: 234 GVKLPGGLEPKGELDCHQL 252 G++L G G DC + Sbjct: 362 GLELT-GTRTHGSPDCDDI 379 >gi|31542331 cysteine-rich, angiogenic inducer, 61 [Homo sapiens] Length = 381 Score = 38.9 bits (89), Expect = 0.004 Identities = 31/79 (39%), Positives = 34/79 (43%), Gaps = 11/79 (13%) Query: 4 LCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGL 63 L LV LL S A HCP + +C P VG LVR+ GCGCC CA L Sbjct: 9 LALVVTLLHLTRLALSTCPAACHCPL----EAPKCAPGVG---LVRD-GCGCCKVCAKQL 60 Query: 64 GMPCGVYTPRCG--SGLRC 80 C P C GL C Sbjct: 61 NEDCSKTQP-CDHTKGLEC 78 >gi|4503123 connective tissue growth factor [Homo sapiens] Length = 349 Score = 38.1 bits (87), Expect = 0.008 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 11/86 (12%) Query: 1 MLPLCLVAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCA 60 M P+ + +LLA P++G C +E RC P G ++ GCGCC CA Sbjct: 6 MGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRC--PAGVSLVL--DGCGCCRVCA 61 Query: 61 LGLGMPCGVYTPRCGSGLRCYPPRGV 86 LG C P C P +G+ Sbjct: 62 KQLGELCTERDP-------CDPHKGL 80 >gi|68448544 CD74 antigen isoform a [Homo sapiens] Length = 296 Score = 38.1 bits (87), Expect = 0.008 Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 6/50 (12%) Query: 202 PNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQ 251 P CD NGN+ P QC+ G G CWCV G ++P +G +C + Sbjct: 230 PKCDENGNYLPLQCY----GSIGYCWCV-FPNGTEVP-NTRSRGHHNCSE 273 >gi|22129776 HtrA serine peptidase 3 [Homo sapiens] Length = 453 Score = 37.0 bits (84), Expect = 0.017 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 14/79 (17%) Query: 9 ALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPG------CGCCATCALG 62 ALLLAA +L E P + ++RC P R PG C CC CA Sbjct: 5 ALLLAALAALALAREPPAAPCPARCDVSRCPSP-------RCPGGYVPDLCNCCLVCAAS 57 Query: 63 LGMPC-GVYTPRCGSGLRC 80 G PC G CG L C Sbjct: 58 EGEPCGGPLDSPCGESLEC 76 >gi|4507923 WNT1 inducible signaling pathway protein 2 precursor [Homo sapiens] Length = 250 Score = 35.8 bits (81), Expect = 0.038 Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 52 GCGCCATCALGLGMPCG-VYTPRCGSGLRCYPPRG 85 GCGCC CA LG PC ++ GL C P G Sbjct: 49 GCGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAG 83 >gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precursor [Homo sapiens] Length = 304 Score = 35.4 bits (80), Expect = 0.050 Identities = 25/75 (33%), Positives = 28/75 (37%), Gaps = 17/75 (22%) Query: 11 LLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGCGCCATCALGLGMPCGV- 69 LLA G G C PC E+ C P GC CGCC CA G C + Sbjct: 46 LLAEGEG---------CAPCRPEE---CAAPRGCLAGRVRDACGCCWECANLEGQLCDLD 93 Query: 70 ----YTPRCGSGLRC 80 + CG L C Sbjct: 94 PSAHFYGHCGEQLEC 108 >gi|13128860 histone deacetylase 1 [Homo sapiens] Length = 482 Score = 32.7 bits (73), Expect = 0.32 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Query: 90 LHTLMHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDR 149 L L H GV M+ +AI E + D+DE D P+ S CS+ R ++ F+ + Sbjct: 370 LRMLPHAPGVQMQAIPEDAIPE--ESGDEDEDD-PDKRISICSSDKRIACEEEFSDSEEE 426 Query: 150 STSGGKMKVN 159 G K N Sbjct: 427 GEGGRKNSSN 436 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.139 0.461 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,436,094 Number of Sequences: 37866 Number of extensions: 771975 Number of successful extensions: 1978 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 83 Number of HSP's that attempted gapping in prelim test: 1894 Number of HSP's gapped (non-prelim): 135 length of query: 258 length of database: 18,247,518 effective HSP length: 100 effective length of query: 158 effective length of database: 14,460,918 effective search space: 2284825044 effective search space used: 2284825044 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.