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Search of human proteins with 62243068
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62243068 insulin-like growth factor binding protein 3
isoform b precursor [Homo sapiens]
(291 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62243068 insulin-like growth factor binding protein 3 isoform... 612 e-175
gi|62243248 insulin-like growth factor binding protein 3 isoform... 605 e-173
gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 234 7e-62
gi|62243290 insulin-like growth factor binding protein 4 precurs... 152 3e-37
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 151 6e-37
gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 134 9e-32
gi|4504615 insulin-like growth factor binding protein 1 precurso... 124 1e-28
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 60 2e-09
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 55 7e-08
gi|93141003 testican 3 isoform 1 [Homo sapiens] 52 5e-07
gi|93141001 testican 3 isoform 2 [Homo sapiens] 52 5e-07
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 52 5e-07
gi|56090548 insulin-like growth factor binding protein-like 1 [H... 51 1e-06
gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 49 5e-06
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 48 9e-06
gi|144953895 nidogen 2 precursor [Homo sapiens] 48 1e-05
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 47 3e-05
gi|115298674 nidogen 1 precursor [Homo sapiens] 46 4e-05
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] 45 6e-05
gi|5901946 endothelial cell-specific molecule 1 isoform a precur... 45 1e-04
gi|208022668 endothelial cell-specific molecule 1 isoform b prec... 45 1e-04
gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 43 3e-04
gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 43 3e-04
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 41 0.001
gi|55770862 thyroglobulin [Homo sapiens] 41 0.001
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 40 0.002
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 38 0.009
gi|218505670 epithelial cell adhesion molecule precursor [Homo s... 36 0.035
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens] 35 0.078
gi|68448544 CD74 antigen isoform a [Homo sapiens] 35 0.10
>gi|62243068 insulin-like growth factor binding protein 3 isoform b
precursor [Homo sapiens]
Length = 291
Score = 612 bits (1577), Expect = e-175
Identities = 291/291 (100%), Positives = 291/291 (100%)
Query: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
Sbjct: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
Query: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
Sbjct: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
Query: 121 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHA 180
SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHA
Sbjct: 121 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHA 180
Query: 181 KDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNC 240
KDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNC
Sbjct: 181 KDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNC 240
Query: 241 DKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 291
DKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
Sbjct: 241 DKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 291
>gi|62243248 insulin-like growth factor binding protein 3 isoform a
precursor [Homo sapiens]
Length = 297
Score = 605 bits (1560), Expect = e-173
Identities = 291/297 (97%), Positives = 291/297 (97%), Gaps = 6/297 (2%)
Query: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE
Sbjct: 1 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 60
Query: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV
Sbjct: 61 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 120
Query: 121 SRLRAYLLPAPPAPG------NASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII 174
SRLRAYLLPAPPAPG NASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII
Sbjct: 121 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII 180
Query: 175 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG 234
IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG
Sbjct: 181 IKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG 240
Query: 235 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 291
VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
Sbjct: 241 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK 297
>gi|10834982 insulin-like growth factor binding protein 5 [Homo
sapiens]
Length = 272
Score = 234 bits (597), Expect = 7e-62
Identities = 123/276 (44%), Positives = 157/276 (56%), Gaps = 34/276 (12%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67
L A L LL GP + LG V CEPCD +AL+ C P P C ELV+EPGC
Sbjct: 3 LLTAVLLLLAAYAGP--------AQSLGSFVHCEPCDEKALSMCPPSPLGC-ELVKEPGC 53
Query: 68 GCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYL 127
GCC+TCAL+EGQ CG+YTERC GLRC P DE +PL ALL GRG+C+N +
Sbjct: 54 GCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYRE----- 108
Query: 128 LPAPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKGHAKDSQR 185
+ + +R + E P+ S PK F P H++I +K K +R
Sbjct: 109 -----------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRR 157
Query: 186 YKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIP 238
K+ +N + E ++E+E GPCRR ME +L LK + PR V++P
Sbjct: 158 KKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLP 217
Query: 239 NCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 274
NCD+KGFYK+KQC+PS+GRKRG CWCVDKYG LPG
Sbjct: 218 NCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
>gi|62243290 insulin-like growth factor binding protein 4 precursor
[Homo sapiens]
Length = 258
Score = 152 bits (385), Expect = 3e-37
Identities = 92/264 (34%), Positives = 124/264 (46%), Gaps = 36/264 (13%)
Query: 31 SAGLGP-----VVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYT 85
+AG GP + C PC LA+C PP C ELVREPGCGCC TCAL G PCG+YT
Sbjct: 13 AAGPGPSLGDEAIHCPPCSEEKLARCRPPVG-CEELVREPGCGCCATCALGLGMPCGVYT 71
Query: 86 ERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRS 145
RCGSGLRC P +PL L+ G+G+C+ + + ++ L P S+ +E
Sbjct: 72 PRCGSGLRCYPPRGVEKPLHTLMHGQGVCMELAEIEAIQESLQP--------SDKDEGDH 123
Query: 146 AGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESK 205
+ SP + R F + + + + KV+ E
Sbjct: 124 PNNSFSPCSAHDRRCLQKHFAKIRDR--------STSGGKMKVN---------GAPREDA 166
Query: 206 RETEYGPCRREMEDTLNHLKFLNVLSPRGVH---IPNCDKKGFYKKKQCRPSKGRKRGFC 262
R G C+ E+ L L + ++ IPNCD+ G + KQC P+ +RG C
Sbjct: 167 RPVPQGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKC 226
Query: 263 WCVD-KYGQPLP-GYTTKGKEDVH 284
WCVD K G LP G KG+ D H
Sbjct: 227 WCVDRKTGVKLPGGLEPKGELDCH 250
>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
[Homo sapiens]
Length = 328
Score = 151 bits (382), Expect = 6e-37
Identities = 99/306 (32%), Positives = 138/306 (45%), Gaps = 46/306 (15%)
Query: 13 LTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAV--------------- 57
L LL+LL G A G A + RC PC LA C PPP
Sbjct: 21 LPLLLLLLG---ASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMP 77
Query: 58 CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117
CAELVREPGCGCC CA EG+ CG+YT RCG GLRC P P PLQAL+ G G C
Sbjct: 78 CAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKR 137
Query: 118 SAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRV----SDPKFHPLHSKII 173
+P +++ +D S G + V ST + PL S +
Sbjct: 138 RDAE--------YGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMK 189
Query: 174 IIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETE----YGPCRREMEDTLNHLKFLNV 229
+ K +++++ + + E ++ PC++E++ L + + +
Sbjct: 190 ELAVFREKVTEQHR---QMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRL 246
Query: 230 LSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPGY-TTKGK 280
RG +HIPNCDK G Y KQC+ S +RG CWCV+ G+ + G T +G
Sbjct: 247 PDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGD 306
Query: 281 EDVHCY 286
+ H +
Sbjct: 307 PECHLF 312
>gi|11321593 insulin-like growth factor binding protein 6 [Homo
sapiens]
Length = 240
Score = 134 bits (337), Expect = 9e-32
Identities = 83/248 (33%), Positives = 113/248 (45%), Gaps = 44/248 (17%)
Query: 29 ASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLT--CALSEGQPCGIYTE 86
A+S G G + RC C A C P V E P GC C EGQ CG+YT
Sbjct: 19 AASPG-GALARCPGCGQGVQAGC-PGGCVEEEDGGSPAEGCAEAEGCLRREGQECGVYTP 76
Query: 87 RCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSA 146
C GL+C P D+ PL+ALL GRG C+ A A PA + E A
Sbjct: 77 NCAPGLQCHPPKDDEAPLRALLLGRGRCLPARA------------PAVAEENPKESKPQA 124
Query: 147 GSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKR 206
G+ V+ + +P ST +S +
Sbjct: 125 GTARPQDVNRRDQQRNP----------------------------GTSTTPSQPNSAGVQ 156
Query: 207 ETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD 266
+TE GPCRR ++ L L+ + +++PNCD +GFY+K+QCR S+G++RG CWCVD
Sbjct: 157 DTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVD 216
Query: 267 KYGQPLPG 274
+ G+ LPG
Sbjct: 217 RMGKSLPG 224
>gi|4504615 insulin-like growth factor binding protein 1 precursor
[Homo sapiens]
Length = 259
Score = 124 bits (310), Expect = 1e-28
Identities = 82/242 (33%), Positives = 109/242 (45%), Gaps = 35/242 (14%)
Query: 39 RCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSP 98
+C PC A LA C P A C+E+ R GCGCC CAL G CG+ T RC GL C+ P
Sbjct: 29 QCAPCSAEKLALCPPVSASCSEVTRSAGCGCCPMCALPLGAACGVATARCARGLSCRALP 88
Query: 99 DEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESP-SVSST 157
E +PL AL G+G CV S S AP A AGS ESP S T
Sbjct: 89 GEQQPLHALTRGQGACVQESDAS--------APHAA----------EAGSPESPESTEIT 130
Query: 158 HRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQST-DTQNFSSESKRETEYGPCRRE 216
FH + A + + + +++ ST D + + PCR E
Sbjct: 131 EEELLDNFHLM-----------APSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIE 179
Query: 217 MEDTLNHLKFLNVLSPRGV---HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKY-GQPL 272
+ + L S + ++PNC+K GFY +QC S + G CWCV + G+ +
Sbjct: 180 LYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRI 239
Query: 273 PG 274
PG
Sbjct: 240 PG 241
>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
Length = 480
Score = 60.5 bits (145), Expect = 2e-09
Identities = 46/121 (38%), Positives = 54/121 (44%), Gaps = 22/121 (18%)
Query: 10 AAALTLLVLLRGPP----VARAGASSA-GLGPVVRCEPCDARALAQCAPPPAVCAELVRE 64
AA L LL+LL P ++RAG S+ G RCEP A+C P P C
Sbjct: 6 AALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEP------ARCPPQPEHCEGGRAR 59
Query: 65 PGCGCCLTCALSEGQPCGIYTERCGSGLRC------QPSPDEARPLQALLDGRGLCVNAS 118
CGCC C EG CG+ CG GL+C S R QA GLCV AS
Sbjct: 60 DACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQA-----GLCVCAS 114
Query: 119 A 119
+
Sbjct: 115 S 115
>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan 1 precursor [Homo sapiens]
Length = 439
Score = 55.1 bits (131), Expect = 7e-08
Identities = 28/68 (41%), Positives = 37/68 (54%), Gaps = 7/68 (10%)
Query: 212 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 271
PC+ EM K ++L G IP C+++G+YK QC S G+ CWCVDKYG
Sbjct: 312 PCQNEMNRIQKLSKGKSLL---GAFIPRCNEEGYYKATQCHGSTGQ----CWCVDKYGNE 364
Query: 272 LPGYTTKG 279
L G +G
Sbjct: 365 LAGSRKQG 372
>gi|93141003 testican 3 isoform 1 [Homo sapiens]
Length = 433
Score = 52.4 bits (124), Expect = 5e-07
Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 212 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 271
PC+ E+ N K V G +IP CD+ G+YK QC S G+ CWCVD+YG
Sbjct: 313 PCQTELS---NIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQ----CWCVDRYGNE 365
Query: 272 LPGYTTKGKED 282
+ G G D
Sbjct: 366 VMGSRINGVAD 376
>gi|93141001 testican 3 isoform 2 [Homo sapiens]
Length = 436
Score = 52.4 bits (124), Expect = 5e-07
Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 212 PCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 271
PC+ E+ N K V G +IP CD+ G+YK QC S G+ CWCVD+YG
Sbjct: 316 PCQTELS---NIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQ----CWCVDRYGNE 368
Query: 272 LPGYTTKGKED 282
+ G G D
Sbjct: 369 VMGSRINGVAD 379
>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 2 [Homo sapiens]
Length = 424
Score = 52.4 bits (124), Expect = 5e-07
Identities = 23/49 (46%), Positives = 29/49 (59%), Gaps = 4/49 (8%)
Query: 234 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKED 282
G+ IP+CD+ G+Y+K QC S G CWCVD+ G L G T G D
Sbjct: 331 GIFIPSCDEDGYYRKMQCDQSSGD----CWCVDQLGLELTGTRTHGSPD 375
>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
sapiens]
Length = 278
Score = 51.2 bits (121), Expect = 1e-06
Identities = 42/115 (36%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 5 RPTLWAAALTLLVLLRGPPVARA-GASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVR 63
R +L L LL+L PP++ + G G G +C PC AP PA +
Sbjct: 3 RLSLLLPLLLLLLLPLLPPLSPSLGIRDVG-GRRPKCGPCRPEGCPAPAPCPAPGISALD 61
Query: 64 EPGCGCCLTCALSEGQPCGIYT-ERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117
E CGCC C +EG CG RCG GL C A P +G GLCV A
Sbjct: 62 E--CGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAP-----EGTGLCVCA 109
>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
Length = 453
Score = 48.9 bits (115), Expect = 5e-06
Identities = 33/88 (37%), Positives = 35/88 (39%), Gaps = 18/88 (20%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67
L AAL L L R PP A PC AR P P V + C
Sbjct: 6 LLLAALAALALAREPPAA----------------PCPARCDVSRCPSPRCPGGYVPDL-C 48
Query: 68 GCCLTCALSEGQPC-GIYTERCGSGLRC 94
CCL CA SEG+PC G CG L C
Sbjct: 49 NCCLVCAASEGEPCGGPLDSPCGESLEC 76
>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
Length = 457
Score = 48.1 bits (113), Expect = 9e-06
Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 22/153 (14%)
Query: 131 PPAPGNASESEEDRSA-GSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKD-SQRYKV 188
P PG+ +E R G S + S D L ++ +G +D + RY
Sbjct: 151 PRCPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAAAPALETQ----PQGDEEDIASRYPT 206
Query: 189 DYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG--VHIPNCDKKGFY 246
+ Q QN ++++ + C +E + L K P+ V IP C G Y
Sbjct: 207 LWTEQVKSRQNKTNKNSVSS----CDQEHQSALEEAK-----QPKNDNVVIPECAHGGLY 257
Query: 247 KKKQCRPSKGRKRGFCWCV-DKYGQPLPGYTTK 278
K QC PS G+CWCV G+P+PG +T+
Sbjct: 258 KPVQCHPS----TGYCWCVLVDTGRPIPGTSTR 286
Score = 37.7 bits (86), Expect = 0.012
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 235 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 274
V IP C+ G Y + QC G +CWCV G+P+ G
Sbjct: 108 VFIPECNDDGTYSQVQCHSYTG----YCWCVTPNGRPISG 143
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 47.8 bits (112), Expect = 1e-05
Identities = 23/51 (45%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 236 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG-YTTKGKEDVHC 285
HIP CD++G + QC S G FCWCVD G +PG T G HC
Sbjct: 959 HIPQCDEQGNFLPLQCHGSTG----FCWCVDPDGHEVPGTQTPPGSTPPHC 1005
Score = 38.9 bits (89), Expect = 0.005
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 9/63 (14%)
Query: 213 CRREMEDTLNHLKFLNVLSPRG-VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQP 271
C R E+ L H +PR ++P CD G + QC K FCWCVDK G+
Sbjct: 1019 CERWRENLLEHYGG----TPRDDQYVPQCDDLGHFIPLQCHG----KSDFCWCVDKDGRE 1070
Query: 272 LPG 274
+ G
Sbjct: 1071 VQG 1073
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 46.6 bits (109), Expect = 3e-05
Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 18/94 (19%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAP-PPAVCAELVREPG 66
L AA L LL+L P++ + +S C PC+ A C P PP C
Sbjct: 11 LGAAGLLLLLL----PLSSSSSSDT-------CGPCEP---ASCPPLPPLGCLLGETRDA 56
Query: 67 CGCCLTCALSEGQPC---GIYTERCGSGLRCQPS 97
CGCC CA EG+PC G C G+ C S
Sbjct: 57 CGCCPMCARGEGEPCGGGGAGRGYCAPGMECVKS 90
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 45.8 bits (107), Expect = 4e-05
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 232 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYS 287
P G+ +P CD G Y QC S G+CWCVD+ G+ + G T+ C S
Sbjct: 870 PPGLFVPECDAHGHYAPTQCHGS----TGYCWCVDRDGREVEGTRTRPGMTPPCLS 921
>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
Length = 357
Score = 45.4 bits (106), Expect = 6e-05
Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 34 LGPVVRCEPCDARALAQCAPPPAVCAELVRE--PGCGCCLTCALSEGQPCGIYTERC--G 89
LG V + C + +C P CA VR GC CCL CA G+ C E C
Sbjct: 26 LGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCS-DLEPCDES 84
Query: 90 SGLRCQPSPD 99
SGL C S D
Sbjct: 85 SGLYCDRSAD 94
>gi|5901946 endothelial cell-specific molecule 1 isoform a precursor
[Homo sapiens]
Length = 184
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 10/63 (15%)
Query: 43 CDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPC-----GIYTERCGSGLRCQPS 97
CD+ ++C P C V + CGCC CA G+ C G+ +CG GLRCQPS
Sbjct: 32 CDS---SECKSSPR-CKRTVLDD-CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
Query: 98 PDE 100
E
Sbjct: 87 NGE 89
>gi|208022668 endothelial cell-specific molecule 1 isoform b
precursor [Homo sapiens]
Length = 134
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 10/63 (15%)
Query: 43 CDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPC-----GIYTERCGSGLRCQPS 97
CD+ ++C P C V + CGCC CA G+ C G+ +CG GLRCQPS
Sbjct: 32 CDS---SECKSSPR-CKRTVLDD-CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPS 86
Query: 98 PDE 100
E
Sbjct: 87 NGE 89
>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
[Homo sapiens]
Length = 435
Score = 43.1 bits (100), Expect = 3e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 10/68 (14%)
Query: 213 CRREMEDTLNHLKFLNVLSPR-GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCV-DKYGQ 270
C +E + L + +PR G+ IP C G YK QC S G+CWCV G+
Sbjct: 227 CDQERQSALEEAQ----QNPREGIVIPECAPGGLYKPVQCHQS----TGYCWCVLVDTGR 278
Query: 271 PLPGYTTK 278
PLPG +T+
Sbjct: 279 PLPGTSTR 286
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
Query: 213 CRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPL 272
CR E L K V +P C + G + + QC G +CWCV G+P+
Sbjct: 95 CRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTG----YCWCVTPDGKPI 146
Query: 273 PGYTTKGKEDVHCYSMQSK 291
G + + K V S+ K
Sbjct: 147 SGSSVQNKTPVCSGSVTDK 165
>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
[Homo sapiens]
Length = 434
Score = 43.1 bits (100), Expect = 3e-04
Identities = 26/68 (38%), Positives = 35/68 (51%), Gaps = 10/68 (14%)
Query: 213 CRREMEDTLNHLKFLNVLSPR-GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCV-DKYGQ 270
C +E + L + +PR G+ IP C G YK QC S G+CWCV G+
Sbjct: 227 CDQERQSALEEAQ----QNPREGIVIPECAPGGLYKPVQCHQS----TGYCWCVLVDTGR 278
Query: 271 PLPGYTTK 278
PLPG +T+
Sbjct: 279 PLPGTSTR 286
Score = 40.0 bits (92), Expect = 0.002
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 8/79 (10%)
Query: 213 CRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPL 272
CR E L K V +P C + G + + QC G +CWCV G+P+
Sbjct: 95 CRLERAQALEQAK----KPQEAVFVPECGEDGSFTQVQCHTYTG----YCWCVTPDGKPI 146
Query: 273 PGYTTKGKEDVHCYSMQSK 291
G + + K V S+ K
Sbjct: 147 SGSSVQNKTPVCSGSVTDK 165
>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
precursor [Homo sapiens]
Length = 304
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 18/97 (18%)
Query: 13 LTLLVLLRGPPVARAGASSAG---------LGPVVRCEPCDARALAQCAPPPAVCAELVR 63
L LLV+L PP + L C PC +CA P A VR
Sbjct: 17 LLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPE---ECAAPRGCLAGRVR 73
Query: 64 EPGCGCCLTCALSEGQPCGI-----YTERCGSGLRCQ 95
+ CGCC CA EGQ C + + CG L C+
Sbjct: 74 D-ACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECR 109
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 40.8 bits (94), Expect = 0.001
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 6/49 (12%)
Query: 231 SPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKG 279
+P + +P+C +G Y+ QC G CWCV+ +G+ LPG +G
Sbjct: 611 TPERLFVPSCTTEGSYEDVQCFS------GECWCVNSWGKELPGSRVRG 653
Score = 38.1 bits (87), Expect = 0.009
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 234 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTT 277
G ++P CD G ++ QC G CWCVD+ G +PG T
Sbjct: 1025 GPYMPQCDAFGSWEPVQCHAGTGH----CWCVDEKGGFIPGSLT 1064
Score = 37.0 bits (84), Expect = 0.020
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 236 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQS 290
++P+C + G Y+ QC+ G CWCVD G+ + G +G E C QS
Sbjct: 315 YVPSCRRNGDYQAVQCQTE-----GPCWCVDAQGKEMHGTRQQG-EPPSCAEGQS 363
Score = 32.3 bits (72), Expect = 0.50
Identities = 19/64 (29%), Positives = 29/64 (45%), Gaps = 8/64 (12%)
Query: 213 CRREMEDTLNHLKFLNVLSPRG--VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQ 270
C + E ++ L P G + +P C +G + QC S+ C+CVD GQ
Sbjct: 658 CPTDCEKQRARMQSLMGSQPAGSTLFVPACTSEGHFLPVQCFNSE------CYCVDAEGQ 711
Query: 271 PLPG 274
+PG
Sbjct: 712 AIPG 715
Score = 30.0 bits (66), Expect = 2.5
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 5/52 (9%)
Query: 236 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYS 287
++P C + G ++ QC+ + GR CWCV G + G G+ V C S
Sbjct: 48 YVPQCAEDGSFQTVQCQ-NDGRS---CWCVGANGSEVLGSRQPGR-PVACLS 94
Score = 30.0 bits (66), Expect = 2.5
Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%)
Query: 236 HIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGK 280
++P C G Y QC + + CWCVD G + G G+
Sbjct: 116 YLPQCQDSGDYAPVQCDVQQVQ----CWCVDAEGMEVYGTRQLGR 156
Score = 28.1 bits (61), Expect = 9.5
Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 5/45 (11%)
Query: 236 HIPNCDKK-GFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKG 279
++P C + G + QC ++G CWCV G+ +PG G
Sbjct: 1165 YVPACRAEDGGFSPVQCDQAQGS----CWCVMDSGEEVPGTRVTG 1205
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/95 (33%), Positives = 41/95 (43%), Gaps = 20/95 (21%)
Query: 8 LWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGC 67
L + L LL+LL AR+G + + C PCD + P C + + C
Sbjct: 16 LLVSLLGLLLLL-----ARSGTRA------LVCLPCDESKCEE----PRNCPGSIVQGVC 60
Query: 68 GCCLTCALSEGQPC----GIYTERCGSGLRCQPSP 98
GCC TCA + C GIY C GLRC P
Sbjct: 61 GCCYTCASQRNESCGGTFGIY-GTCDRGLRCVIRP 94
>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
[Homo sapiens]
Length = 250
Score = 38.1 bits (87), Expect = 0.009
Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 1/60 (1%)
Query: 38 VRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCG-IYTERCGSGLRCQP 96
VR + C PP + GCGCC CA G+PC ++ GL CQP
Sbjct: 21 VRTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVCQP 80
>gi|218505670 epithelial cell adhesion molecule precursor [Homo
sapiens]
Length = 314
Score = 36.2 bits (82), Expect = 0.035
Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 5/36 (13%)
Query: 234 GVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYG 269
G++ P+CD+ G +K KQC + CWCV+ G
Sbjct: 93 GLYDPDCDESGLFKAKQCNGT-----SMCWCVNTAG 123
>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
Length = 476
Score = 35.0 bits (79), Expect = 0.078
Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 16/99 (16%)
Query: 5 RPTLWAAALT------LLVLLRGPPVARAGASSAGLGPVVR--CEPCDARALAQCAPPPA 56
RP L A L LL+LL PV AGA P C+P AL CA
Sbjct: 3 RPQLRTAGLGRCLLPGLLLLL--VPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTT 60
Query: 57 VCAELVREPGCGCCLTCALSEGQPC-GIYTERCGSGLRC 94
+L C CC C +E + C G + C GL+C
Sbjct: 61 PVFDL-----CRCCRVCPAAEREVCGGAQGQPCAPGLQC 94
>gi|68448544 CD74 antigen isoform a [Homo sapiens]
Length = 296
Score = 34.7 bits (78), Expect = 0.10
Identities = 16/42 (38%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 238 PNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKG 279
P CD+ G Y QC S G +CWCV G +P ++G
Sbjct: 230 PKCDENGNYLPLQCYGSIG----YCWCVFPNGTEVPNTRSRG 267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,787,671
Number of Sequences: 37866
Number of extensions: 732400
Number of successful extensions: 3099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 2980
Number of HSP's gapped (non-prelim): 166
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.