Guide to the Human Genome
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Name: HTRA4 Sequence: fasta or formatted (476aa) NCBI GI: 24308541
Description:

HtrA serine peptidase 4 precursor

Referenced in:

Growth Hormone and Related Hormones
Serine Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.8         37           2
 C cysteine            3.8         18           2
 D aspartate           5.0         24           1
 E glutamate           3.8         18           2
 F phenylalanine       2.1         10           1
 G glycine             9.5         45           2
 H histidine           1.7          8           1
 I isoleucine          4.2         20           2
 K lysine              3.8         18           2
 L leucine            11.3         54           5
 M methionine          1.9          9           1
 N asparagine          3.8         18           1
 P proline             6.5         31           1
 Q glutamine           4.0         19           2
 R arginine            6.1         29           2
 S serine              6.5         31           2
 T threonine           5.3         25           4
 V valine             10.1         48           2
 W tryptophan          0.8          4           1
 Y tyrosine            2.1         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   HtrA serine peptidase 4 precursor 
HTRA1                 0.479   HtrA serine peptidase 1 precursor 
HTRA3                 0.426   HtrA serine peptidase 3 
HTRA2                 0.287   HtrA serine peptidase 2 isoform 1 preproprotein [Homo...
HTRA2                 0.072   HtrA serine peptidase 2 isoform 2 
IGFBP7                0.069   insulin-like growth factor binding protein 7 
IGFBPL1               0.063   insulin-like growth factor binding protein-like 1 [H...
ESM1                  0.032   endothelial cell-specific molecule 1 isoform a precur...
ESM1                  0.032   endothelial cell-specific molecule 1 isoform b prec...
NOV                   0.027   nephroblastoma overexpressed precursor 
WISP2                 0.022   WNT1 inducible signaling pathway protein 2 precursor ...
CTGF                  0.019   connective tissue growth factor 
CYR61                 0.018   cysteine-rich, angiogenic inducer, 61 
KAZALD1               0.017   Kazal-type serine peptidase inhibitor domain 1 precu...
CRIM1                 0.016   cysteine-rich motor neuron 1 
AGRN                  0.015   agrin 
IGFBP2                0.013   insulin-like growth factor binding protein 2, 36kDa ...
SYNPO2                0.013   synaptopodin 2 isoform c 
SYNPO2                0.013   synaptopodin 2 isoform b 
SYNPO2                0.013   synaptopodin 2 isoform a 
PDZD7                 0.013   PDZ domain containing 7 
LCE1B                 0.013   late cornified envelope 1B 
PDZRN3                0.013   PDZ domain containing ring finger 3 
KRTAP2-2              0.013   keratin associated protein 2-2 
WISP3                 0.013   WNT1 inducible signaling pathway protein 3 isoform 3...
WISP3                 0.013   WNT1 inducible signaling pathway protein 3 isoform 1 ...
LOC100131696          0.013   PREDICTED: keratin associated protein 
LOC100288060          0.013   PREDICTED: hypothetical protein XP_002343557 
IGFBP5                0.012   insulin-like growth factor binding protein 5 
LOC100292632          0.012   PREDICTED: hypothetical protein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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