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Search of human proteins with 61966703
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61966703 NHS-like 2 [Homo sapiens]
(709 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61966703 NHS-like 2 [Homo sapiens] 1418 0.0
gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens] 176 5e-44
gi|209862849 Nance-Horan syndrome protein isoform 2 [Homo sapiens] 176 5e-44
gi|221139926 NHS-like 1 [Homo sapiens] 79 2e-14
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 4e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 68 3e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 5e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 62 2e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 62 2e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 59 2e-08
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 59 2e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 55 2e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 55 3e-07
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 54 5e-07
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 54 7e-07
gi|91982772 mucin 17 [Homo sapiens] 53 9e-07
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 53 9e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 52 2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 2e-06
gi|119943102 CREB binding protein isoform b [Homo sapiens] 52 2e-06
gi|119943104 CREB binding protein isoform a [Homo sapiens] 52 2e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 2e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 3e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 51 3e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 51 3e-06
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 51 4e-06
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 51 4e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 50 6e-06
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 50 7e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 7e-06
>gi|61966703 NHS-like 2 [Homo sapiens]
Length = 709
Score = 1418 bits (3671), Expect = 0.0
Identities = 709/709 (100%), Positives = 709/709 (100%)
Query: 1 MESMGMVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVS 60
MESMGMVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVS
Sbjct: 1 MESMGMVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVS 60
Query: 61 LNKVPPLVPKEAATLLVARDNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLET 120
LNKVPPLVPKEAATLLVARDNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLET
Sbjct: 61 LNKVPPLVPKEAATLLVARDNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLET 120
Query: 121 GPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQ 180
GPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQ
Sbjct: 121 GPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQ 180
Query: 181 QEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLE 240
QEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLE
Sbjct: 181 QEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLE 240
Query: 241 HQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIEC 300
HQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIEC
Sbjct: 241 HQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIEC 300
Query: 301 TQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTV 360
TQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTV
Sbjct: 301 TQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTV 360
Query: 361 SMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGM 420
SMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGM
Sbjct: 361 SMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGM 420
Query: 421 SISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE 480
SISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE
Sbjct: 421 SISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE 480
Query: 481 SPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPP 540
SPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPP
Sbjct: 481 SPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPP 540
Query: 541 RSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQP 600
RSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQP
Sbjct: 541 RSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQP 600
Query: 601 PQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYV 660
PQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYV
Sbjct: 601 PQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYV 660
Query: 661 AEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQADSEREASPLG 709
AEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQADSEREASPLG
Sbjct: 661 AEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQADSEREASPLG 709
>gi|38093637 Nance-Horan syndrome protein isoform 1 [Homo sapiens]
Length = 1630
Score = 176 bits (447), Expect = 5e-44
Identities = 158/467 (33%), Positives = 209/467 (44%), Gaps = 69/467 (14%)
Query: 97 QQRHMPERPSKIGL-------LTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEE 149
+Q PERP L + + S LE P + SV T+ T + +D
Sbjct: 714 RQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSH-FSVDTEGYYTSMHFDCG 772
Query: 150 QKANEACALPFASTSSE---GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPT 206
K N++ +A+ E G ++ + + Q H+RQ SIS RK K KP+PP
Sbjct: 773 LKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSISFRKPKAKPTPPK 832
Query: 207 RSVSLVKD----------EPGLLPEGGSALPKDQRPKSLCLSLEH--------------- 241
RS SL K EP + G LP R L L +
Sbjct: 833 RSSSLRKSDGNADISEKKEPKI--SSGQHLPHSSREMKLPLDFANTPSRMENANLPTKQE 890
Query: 242 --------QGHHSSHPDAQGHPAIPNHKDP--ESTQFSHHWYLTDWKSGDTYQSLSSSST 291
QG DA IP KD EST ++ W L D K+ D Y+SLS+SST
Sbjct: 891 PSWINQSEQGIKEPQLDASD---IPPFKDEVAESTHYADLWLLNDLKTNDPYRSLSNSST 947
Query: 292 ATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSS 351
ATGTTVIEC + SSES S S SRATTPS S++ E + ++SP + GL SPSSGYSS
Sbjct: 948 ATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFK-LASPEKLAGLASPSSGYSS 1006
Query: 352 QSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTS 411
QSETPT + + G L P S + +P VPERKSSL S + +LP+
Sbjct: 1007 QSETPTSSFPTAFFSGPLSPGGS--KRKPKVPERKSSLQQPSLKDGTISLSKDLELPIIP 1064
Query: 412 SPNLDLSGMSISI------RSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSV 465
+LDLS + + R V H+ + G L P+ I P + L+SV
Sbjct: 1065 PTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTI----LKSV 1120
Query: 466 RLRSVSKSE----PEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEK 508
LRS++KSE E++ Y EE P K +P A K
Sbjct: 1121 NLRSINKSEEVKQKEENNTDLPYLEESTLTTAALSPS-KIRPHTANK 1166
>gi|209862849 Nance-Horan syndrome protein isoform 2 [Homo sapiens]
Length = 1474
Score = 176 bits (447), Expect = 5e-44
Identities = 158/467 (33%), Positives = 209/467 (44%), Gaps = 69/467 (14%)
Query: 97 QQRHMPERPSKIGL-------LTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEE 149
+Q PERP L + + S LE P + SV T+ T + +D
Sbjct: 558 RQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSH-FSVDTEGYYTSMHFDCG 616
Query: 150 QKANEACALPFASTSSE---GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPT 206
K N++ +A+ E G ++ + + Q H+RQ SIS RK K KP+PP
Sbjct: 617 LKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSISFRKPKAKPTPPK 676
Query: 207 RSVSLVKD----------EPGLLPEGGSALPKDQRPKSLCLSLEH--------------- 241
RS SL K EP + G LP R L L +
Sbjct: 677 RSSSLRKSDGNADISEKKEPKI--SSGQHLPHSSREMKLPLDFANTPSRMENANLPTKQE 734
Query: 242 --------QGHHSSHPDAQGHPAIPNHKDP--ESTQFSHHWYLTDWKSGDTYQSLSSSST 291
QG DA IP KD EST ++ W L D K+ D Y+SLS+SST
Sbjct: 735 PSWINQSEQGIKEPQLDASD---IPPFKDEVAESTHYADLWLLNDLKTNDPYRSLSNSST 791
Query: 292 ATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSS 351
ATGTTVIEC + SSES S S SRATTPS S++ E + ++SP + GL SPSSGYSS
Sbjct: 792 ATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFK-LASPEKLAGLASPSSGYSS 850
Query: 352 QSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTS 411
QSETPT + + G L P S + +P VPERKSSL S + +LP+
Sbjct: 851 QSETPTSSFPTAFFSGPLSPGGS--KRKPKVPERKSSLQQPSLKDGTISLSKDLELPIIP 908
Query: 412 SPNLDLSGMSISI------RSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSV 465
+LDLS + + R V H+ + G L P+ I P + L+SV
Sbjct: 909 PTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTI----LKSV 964
Query: 466 RLRSVSKSE----PEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEK 508
LRS++KSE E++ Y EE P K +P A K
Sbjct: 965 NLRSINKSEEVKQKEENNTDLPYLEESTLTTAALSPS-KIRPHTANK 1010
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 78.6 bits (192), Expect = 2e-14
Identities = 139/568 (24%), Positives = 209/568 (36%), Gaps = 107/568 (18%)
Query: 190 SKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQ------G 243
S++ISL+KAKK P PP+R+ SL + +P+ S +SL +L+H G
Sbjct: 660 SRNISLKKAKKPPLPPSRTDSLRR-----IPKKSSQCNGQVLNESLIATLQHSLQLSLPG 714
Query: 244 HHSSHPDAQG-----HPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTT-- 296
S P P +P + + +T + + Y ++ + + T+
Sbjct: 715 KSGSSPSQSPCSDLEEPWLPRSRSQSTVSAGSS--MTSATTPNVYSLCGATPSQSDTSSV 772
Query: 297 ----------VIECTQVQ--------GSSESLASPST----------SRATTPSQLSIEV 328
I+ T +Q G S S P+ SRAT P V
Sbjct: 773 KSEYTDPWGYYIDYTGMQEDPGNPAGGCSTSSGVPTGNGPVRHVQEGSRATMPQVPGGSV 832
Query: 329 EAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSS 388
+ + I SP + ++SPSSGYSSQS TPT + + L + P + + +P VPERKSS
Sbjct: 833 KPK-IMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLKSVSPANGKGKPKPKVPERKSS 891
Query: 389 LPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTN 448
L SS ++ S S+S + T+ S + + V +
Sbjct: 892 --------------------LISSVSISSSSTSLSSSTSTEGSGTMKKLDPAV-----GS 926
Query: 449 PNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEK 508
P P P V RS P + + + P + VF P + P
Sbjct: 927 PPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHS-PVFPPPPPEALIPFCSP 985
Query: 509 PPVARRPPSLVHKP--PSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSF 566
P PP P P P L P L P S A PL R P +S
Sbjct: 986 PDWCLSPPRPALSPILPDSPVSLPLPPPLL---PSSEPPPAPPLDPKFMKDTRPPFTNSG 1042
Query: 567 PDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEG-PKVRVLPER------I 619
S G PS+ T +PP + E V++ P R
Sbjct: 1043 QPESSRGSLRPPSTK-------------EETSRPPMPLITTEALQMVQLRPVRKNSGAEA 1089
Query: 620 SLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKC 679
+ S+ A++++ + P KPS +L + T +ME+ P S +L K
Sbjct: 1090 AQLSERTAQEQRTPVAPQYHLKPSA-FLKSRNSTNEMES----ESQPASVTSSLPTPAKS 1144
Query: 680 PATGD--DLQSLGQRVTSTPQADSEREA 705
+ GD G V+ +P A S EA
Sbjct: 1145 SSQGDHGSAAERGGPVSRSPGAPSAGEA 1172
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 70.9 bits (172), Expect = 4e-12
Identities = 166/712 (23%), Positives = 238/712 (33%), Gaps = 135/712 (18%)
Query: 34 MTPSATSQSNQVNENGKNPSCGNSW-VSLNKVPPLVPKEAATLLVARD--NPAGCSGSAG 90
+TP+A G+ P + + +P P+ T NPA ++G
Sbjct: 39 VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASG 98
Query: 91 YPERLIQQRHMPERPSKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQ 150
ER ++ P SGT+R GP G R + +E
Sbjct: 99 RGERAPPAKNTSPGPVSSPGRASGTTR--PGPLGQKGLR--------------ISAEETV 142
Query: 151 KANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPS----PPT 206
+A P S S G+ + + A RR R+ + + PS PPT
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 207 ----RSVSLVKD----EPGLL----PEGGSALPKDQRPKSLCLSLEHQGHHS---SHPDA 251
+SVS + EP P G L QRP S LS S S P A
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGL---QRPASRSLSSSATPLSSPARSGPSA 259
Query: 252 QGHPAIPNHKD---PESTQFSHHWYLTDWK--SGDTYQSLSSSSTATGTTVIECTQVQGS 306
+G P P H P+ Q +T + + LSSS AT + Q Q
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA-ALQSQAP 318
Query: 307 SESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTL 366
A+P +S T + + S+P L SP + SQ+ T + ++ T
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
Query: 367 GHLP-PPSSSVRVRPVVPERKSSLPPT----SPMEKFPKSRLSFDLPLTSSPNLDLSGMS 421
LP PP S + P +LPP SP P S L+ P +PN
Sbjct: 379 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA--TPSPQAPNA------ 430
Query: 422 ISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIES 481
++ H + F P+ P+ + V + S+ + +
Sbjct: 431 --------LAVHLLQAPFSPP------PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
Query: 482 PEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPR 541
P P + T PP A PP+A P L PP P P LA PP
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAP-PPLAAPPLQLAKPPPQAP-------PALATPPL 528
Query: 542 SSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPP 601
++ P P P+SFP G++P +A SL +P A+ PP
Sbjct: 529 QAL----PSP-----------PASFP-GQAPFSPSA--SLPMSPLATP----------PP 560
Query: 602 QGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVA 661
Q P ++V PP P L P PT + V+
Sbjct: 561 QAPPVLAAPLLQV---------------------PPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 662 EPRLPLS----PIITLEEDTKCPATGDDLQSLGQRVTSTPQADSEREASPLG 709
PRL L+ P +G DL TSTP+ ++ P G
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 68.2 bits (165), Expect = 3e-11
Identities = 122/473 (25%), Positives = 180/473 (38%), Gaps = 99/473 (20%)
Query: 148 EEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRS-KSISLRKAKKKPSPPT 206
E A+ + P S GS S + A S + Q S +S+SLRK K+ P PP
Sbjct: 443 ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPR 502
Query: 207 RSVSLVKDEPGL-LPEGGSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPES 265
R+ SL + GL +P+G LP PK P+ + P +P P +
Sbjct: 503 RTHSL--HQRGLAVPDGPLGLP----PK---------------PERKQQPQLPR---PPT 538
Query: 266 TQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLS 325
T S +G+ + P+ + + P LS
Sbjct: 539 TGGS----------------------------------EGAGAAPCPPNPANSWVPG-LS 563
Query: 326 IEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPER 385
R SP R +SPSSGYSSQS TPT G PP+S + +P PER
Sbjct: 564 PGGSRRPPRSPERT---LSPSSGYSSQSGTPTLPPK-----GLAGPPASPGKAQPPKPER 615
Query: 386 KSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSI--SIRSKTKVSRHHS-ETNFGVK 442
+SL SP S S + D SG I + + + H F
Sbjct: 616 VTSL--RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPP 673
Query: 443 LAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERK-- 500
++ +PN P P + + + S + + P+ +P+ P E ++
Sbjct: 674 PSKPRSPN-PAAPALAAPAVVPGPV-STTDASPQSP-PTPQTTLTPLQESPVISKDQSPP 730
Query: 501 -TKPPVAEKPPVARRPPSLVHKPPSVPE--EYALTSPTLAMPPRSSIQHAR------PLP 551
+ PP PP + P +V + PS E E L P PP + + P P
Sbjct: 731 PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPP 790
Query: 552 QDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGS 604
++++ V P+P+ G S +P LV +P ASSS A + Q P GS
Sbjct: 791 EEAFFSVASPEPA--------GPSGSP-ELVSSPAASSSSA--TALQIQPPGS 832
Score = 38.1 bits (87), Expect = 0.028
Identities = 62/244 (25%), Positives = 96/244 (39%), Gaps = 64/244 (26%)
Query: 320 TPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSS----S 375
TPS L + V R + +PG P +P+ G S+ + +S + +P PSS +
Sbjct: 880 TPSLLQM-VRLRSVGAPGGAP---TPALGPSAPQKPLRRALSGRAS--PVPAPSSGLHAA 933
Query: 376 VRVRP---VVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSR 432
VR++ E SS P P E P+ S P +++ + G
Sbjct: 934 VRLKACSLAASEGLSSAQPNGPPEAEPRPPQS---PASTASFIFSKG------------- 977
Query: 433 HHSETNFGVKLAQKTNPNQPIMPMVTQSDLRS---VRLRSVSKSEPEDDIESPEYAEEPR 489
++K +P+ P TQ+DL+ LRS+S+ P P+
Sbjct: 978 -----------SRKLQLERPVSPE-TQADLQRNLVAELRSISEQRP------------PQ 1013
Query: 490 AEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARP 549
A + K PPVA KP V PP+ PS P LT+P P + + R
Sbjct: 1014 APK----KSPKAPPPVARKPSVGVPPPA----SPSYPRAEPLTAPPTNGLPHTQDRTKRE 1065
Query: 550 LPQD 553
L ++
Sbjct: 1066 LAEN 1069
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.9 bits (154), Expect = 5e-10
Identities = 117/464 (25%), Positives = 163/464 (35%), Gaps = 103/464 (22%)
Query: 304 QGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETP--TPTVS 361
+G +S++S S T PS AR S G GL P+S S S TP +P S
Sbjct: 194 EGPRKSVSSASEHSTTEPSPA-----ARRRPSAGG--GLQRPASRSLSSSATPLSSPARS 246
Query: 362 MSLTLG--------HLPPPSSSVRVRP--VVPERKSSLPPTSPMEKFPKSRLSFDLPLTS 411
G P P +RP V P RK + P P+ P + S P
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP--P 304
Query: 412 SPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTN---PNQPIMPMVTQSDLRSVRLR 468
SP+ S ++ T S+ + T+ G Q T+ P+ P+ P+ T L
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQ--ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362
Query: 469 SVSKSEPEDDIESPEYA-------EEPRAEEVFTLPERKTKPPVAE---------KPPVA 512
P SP + + P A V L + PP PPV+
Sbjct: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422
Query: 513 -------RRPPSLVHKPPSVPEEY--------ALTSPTLAMPPRSS--IQHARPLPQDSY 555
+ PPSL P VP + T P A PP ++ +Q A+P PQ
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482
Query: 556 TVVRKP------KPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEG 609
+ P P+SFP G++P +A SL +P A+ PPQ
Sbjct: 483 ALATPPLQALPSPPASFP-GQAPFSPSA--SLPMSPLATP----------PPQAPPVLAA 529
Query: 610 PKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLS- 668
P ++V PP P L P PT + V+ PRL L+
Sbjct: 530 PLLQV---------------------PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568
Query: 669 ---PIITLEEDTKCPATGDDLQSLGQRVTSTPQADSEREASPLG 709
P +G DL TSTP+ ++ P G
Sbjct: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612
Score = 53.5 bits (127), Expect = 7e-07
Identities = 136/583 (23%), Positives = 193/583 (33%), Gaps = 84/583 (14%)
Query: 79 RDNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLETGPGGAS---RFRERSLSV 135
R P G G E + + E P + L++G R +GP + RS +
Sbjct: 116 RPGPLGQKGLRISAEETVARGKATEAPKR-SALSAGARRDTSGPTPGTPSPAMARRSRAA 174
Query: 136 PTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISL 195
T+ G + S++SE S + + A+ + A QR S SL
Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA-RRRPSAGGGLQRPASRSL 233
Query: 196 RKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQ------------G 243
+ S P RS + P A P +PK L Q G
Sbjct: 234 SSSATPLSSPARSGPSARGTPR-----APAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288
Query: 244 HHSSHPDAQGHP-AIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQ 302
SS P A P A P+ P S Q T S ++ + TT +
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQ--------------TLPSPPATPPSQATTSLGSPT 334
Query: 303 VQGSSESLASPSTSR-ATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVS 361
+Q + L SP S AT P Q + + +P PP +S S TP+P
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP-----ASPPLSPLATPSPQAP 389
Query: 362 MSLTLGHL-----PPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLD 416
+L + L PPPS V+ P P +P + P S + L + SP
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP--- 446
Query: 417 LSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPE 476
+ S + + Q P P + L++ L S S P
Sbjct: 447 ---PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA--LPSPPASFPG 501
Query: 477 DDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTL 536
SP +LP P + PPV P L+ PPS P SPTL
Sbjct: 502 QAPFSPS----------ASLPMSPLATPPPQAPPVLAAP--LLQVPPSPP-----ASPTL 544
Query: 537 AMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSG 596
P R P P +V + G P S +PSS + P + + S
Sbjct: 545 QAPRRP------PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS--SA 596
Query: 597 TQQPPQGSVEDEGPK---VRVLPERISLQSQEEAEKKKGKIPP 636
T P + D GP+ P L + A +G PP
Sbjct: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 639
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 61.6 bits (148), Expect = 2e-09
Identities = 124/604 (20%), Positives = 215/604 (35%), Gaps = 96/604 (15%)
Query: 115 TSRLETGPGGASRF----RERSLSVPTDSGTTDVDYDEE-QKANEACALPFASTSSEGSN 169
+S+ P GAS+ +RS P T V EE + + +S+SS S+
Sbjct: 74 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 133
Query: 170 SADNIASLSAQQEAQHRRQRSKSISLR-----KAKKKPSPPTRSVSLVKDEPGLLPEGGS 224
S+ I + + + + R+ K + ++ + KKKP+P +P ++ E GS
Sbjct: 134 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP----------KPPVVDEAGS 183
Query: 225 ALPKDQRPKSL--CLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLT------- 275
L + + +H +S P P P ++ S LT
Sbjct: 184 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 243
Query: 276 DWKSGDTYQSLSSSSTATGTTVIECTQV--QGSSESLASPSTSRATTPSQLSIEVEAREI 333
+ K T +S+ TT + TQ + S++ LA S A + + +
Sbjct: 244 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 303
Query: 334 SSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTS 393
++P + P +P S+ + PTPT S P ++ + P P+ + PT+
Sbjct: 304 TTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA---PTT 359
Query: 394 PMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPI 453
E P + P +P + +S + + T +K P P
Sbjct: 360 TKEPAPTT------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-----PKKPAPTTPK 408
Query: 454 MPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVAR 513
P T + EP +P +EP P K P K P
Sbjct: 409 EPAPT------------TPKEP-----TPTTPKEP-------APTTKEPAPTTPKEPA-- 442
Query: 514 RPPSLVHKP-PSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSP 572
P+ KP P+ P+E A T+P P + + S T ++P P++ +
Sbjct: 443 --PTAPKKPAPTTPKEPAPTTPKEPAPTTTK--------EPSPTTPKEPAPTTTKSAPTT 492
Query: 573 GESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLP------ERISLQSQEE 626
+ AP++ P + + + T++P + ++ P P E +E
Sbjct: 493 TKEPAPTTTKSAP-TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551
Query: 627 AEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPR-----LPLSPIITLEEDTKCPA 681
A K P PK+P+ T+PT + P P P T E+ P
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-APT 610
Query: 682 TGDD 685
T ++
Sbjct: 611 TPEE 614
Score = 41.6 bits (96), Expect = 0.003
Identities = 71/376 (18%), Positives = 118/376 (31%), Gaps = 34/376 (9%)
Query: 312 SPSTSRATTPSQ-LSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLP 370
+P TTP + + ++P P + S+ +++ PT T S T P
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-P 511
Query: 371 PPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKV 430
P+++ P P+ + P P PK P +P + +
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 431 SRHHSETNFGVKLA----QKTNPNQPIMPM-VTQSDLRSVRLRSVSKSEPEDDIESPEYA 485
+ + KL +K P P P T +L + + PE+ + A
Sbjct: 571 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 630
Query: 486 EEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQ 545
P + K P K P P P L P P + + +
Sbjct: 631 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 690
Query: 546 HARP--LPQDSYTVVRKPKPSSFPDGRSP------------------GESTAPSSL---- 581
P + + T KP P++ P G +P + TAP++L
Sbjct: 691 ELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 749
Query: 582 VFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKK 641
TP + T + P + D+ P E +E A K P P+
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 808
Query: 642 PSVLYLPLTSPTAQME 657
P +++PT E
Sbjct: 809 PPPTTSEVSTPTTTKE 824
Score = 41.2 bits (95), Expect = 0.003
Identities = 67/360 (18%), Positives = 118/360 (32%), Gaps = 34/360 (9%)
Query: 312 SPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPP 371
+P+T + P +L+ S+ P +P + + P PT P
Sbjct: 680 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE------PA 733
Query: 372 PSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVS 431
P++ P + + PT+P + PK +S D + +
Sbjct: 734 PTTPKGTAPTTLKEPA---PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 790
Query: 432 RHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRS-VRLRSVSKSEPEDDIESPEYAEEPRA 490
+ + T +K P P P T S++ + + + D +PE + EP
Sbjct: 791 KEPAPTT-----PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 845
Query: 491 EEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSP--TLAMPP--RSSIQH 546
+ + P+ P K P A +P E T+P T A P + +
Sbjct: 846 KALENSPKEPGVPTT--KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 903
Query: 547 ARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQ--QPPQGS 604
+ T S+ +P + T + P +++ + T+ P+
Sbjct: 904 TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE-- 961
Query: 605 VEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPR 664
E PK R + +A K + P PKKP+ P T P + PR
Sbjct: 962 -ETAKPKDRA--------TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1012
Score = 38.9 bits (89), Expect = 0.017
Identities = 86/440 (19%), Positives = 149/440 (33%), Gaps = 51/440 (11%)
Query: 275 TDWKSGDTYQSLSSSSTA---TGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAR 331
T KS T S +T TT E + +P TTP + + +
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 332 EISSPGRPPGLMSPSSGYSSQSETPTPTVSMSL--TLGHLPPPSSSVRVRPVVPERKSSL 389
+ + P +P + + TPT L T P P++ + P PE +
Sbjct: 559 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 618
Query: 390 PPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNP 449
P P PK+ ++PN + + T K T P
Sbjct: 619 TPEEPAPTTPKA---------AAPN---------------TPKEPAPTT--PKEPAPTTP 652
Query: 450 NQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKP 509
+P T + + + + ++ +P ++P +E+ ++ +KP
Sbjct: 653 KEP--APTTPKETAPTTPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708
Query: 510 PVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDG 569
P + P+ P+E A T+P P L + + T +KP P
Sbjct: 709 ----APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL--- 761
Query: 570 RSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEK 629
+P + P+S A ++ + T + P PE + E +
Sbjct: 762 -APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP-APTTPETPPPTTSEVSTP 819
Query: 630 KKGKIPPPVPKKPSVLYLPLTS-PTAQ-MEAYVAEPRLPL--SPIITLEEDT---KCPAT 682
K P + K P L++ PT + +E EP +P +P T E T K T
Sbjct: 820 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 879
Query: 683 GDDLQSLGQRVTSTPQADSE 702
DL++ + T+ P+ E
Sbjct: 880 ERDLRTTPETTTAAPKMTKE 899
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 61.6 bits (148), Expect = 2e-09
Identities = 124/604 (20%), Positives = 215/604 (35%), Gaps = 96/604 (15%)
Query: 115 TSRLETGPGGASRF----RERSLSVPTDSGTTDVDYDEE-QKANEACALPFASTSSEGSN 169
+S+ P GAS+ +RS P T V EE + + +S+SS S+
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 174
Query: 170 SADNIASLSAQQEAQHRRQRSKSISLR-----KAKKKPSPPTRSVSLVKDEPGLLPEGGS 224
S+ I + + + + R+ K + ++ + KKKP+P +P ++ E GS
Sbjct: 175 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP----------KPPVVDEAGS 224
Query: 225 ALPKDQRPKSL--CLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLT------- 275
L + + +H +S P P P ++ S LT
Sbjct: 225 GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTV 284
Query: 276 DWKSGDTYQSLSSSSTATGTTVIECTQV--QGSSESLASPSTSRATTPSQLSIEVEAREI 333
+ K T +S+ TT + TQ + S++ LA S A + + +
Sbjct: 285 ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPAL 344
Query: 334 SSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTS 393
++P + P +P S+ + PTPT S P ++ + P P+ + PT+
Sbjct: 345 TTP-KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA---PTT 400
Query: 394 PMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPI 453
E P + P +P + +S + + T +K P P
Sbjct: 401 TKEPAPTT------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT-----PKKPAPTTPK 449
Query: 454 MPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVAR 513
P T + EP +P +EP P K P K P
Sbjct: 450 EPAPT------------TPKEP-----TPTTPKEP-------APTTKEPAPTTPKEPA-- 483
Query: 514 RPPSLVHKP-PSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSP 572
P+ KP P+ P+E A T+P P + + S T ++P P++ +
Sbjct: 484 --PTAPKKPAPTTPKEPAPTTPKEPAPTTTK--------EPSPTTPKEPAPTTTKSAPTT 533
Query: 573 GESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLP------ERISLQSQEE 626
+ AP++ P + + + T++P + ++ P P E +E
Sbjct: 534 TKEPAPTTTKSAP-TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592
Query: 627 AEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPR-----LPLSPIITLEEDTKCPA 681
A K P PK+P+ T+PT + P P P T E+ P
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL-APT 651
Query: 682 TGDD 685
T ++
Sbjct: 652 TPEE 655
Score = 41.6 bits (96), Expect = 0.003
Identities = 71/376 (18%), Positives = 118/376 (31%), Gaps = 34/376 (9%)
Query: 312 SPSTSRATTPSQ-LSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLP 370
+P TTP + + ++P P + S+ +++ PT T S T P
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-P 552
Query: 371 PPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKV 430
P+++ P P+ + P P PK P +P + +
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 431 SRHHSETNFGVKLA----QKTNPNQPIMPM-VTQSDLRSVRLRSVSKSEPEDDIESPEYA 485
+ + KL +K P P P T +L + + PE+ + A
Sbjct: 612 TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 671
Query: 486 EEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQ 545
P + K P K P P P L P P + + +
Sbjct: 672 AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 731
Query: 546 HARP--LPQDSYTVVRKPKPSSFPDGRSP------------------GESTAPSSL---- 581
P + + T KP P++ P G +P + TAP++L
Sbjct: 732 ELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 790
Query: 582 VFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKK 641
TP + T + P + D+ P E +E A K P P+
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDK-PAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 849
Query: 642 PSVLYLPLTSPTAQME 657
P +++PT E
Sbjct: 850 PPPTTSEVSTPTTTKE 865
Score = 41.2 bits (95), Expect = 0.003
Identities = 67/360 (18%), Positives = 118/360 (32%), Gaps = 34/360 (9%)
Query: 312 SPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPP 371
+P+T + P +L+ S+ P +P + + P PT P
Sbjct: 721 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE------PA 774
Query: 372 PSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVS 431
P++ P + + PT+P + PK +S D + +
Sbjct: 775 PTTPKGTAPTTLKEPA---PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP 831
Query: 432 RHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRS-VRLRSVSKSEPEDDIESPEYAEEPRA 490
+ + T +K P P P T S++ + + + D +PE + EP
Sbjct: 832 KEPAPTT-----PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 886
Query: 491 EEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSP--TLAMPP--RSSIQH 546
+ + P+ P K P A +P E T+P T A P + +
Sbjct: 887 KALENSPKEPGVPTT--KTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATT 944
Query: 547 ARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQ--QPPQGS 604
+ T S+ +P + T + P +++ + T+ P+
Sbjct: 945 TEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPE-- 1002
Query: 605 VEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPR 664
E PK R + +A K + P PKKP+ P T P + PR
Sbjct: 1003 -ETAKPKDRA--------TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1053
Score = 38.9 bits (89), Expect = 0.017
Identities = 86/440 (19%), Positives = 149/440 (33%), Gaps = 51/440 (11%)
Query: 275 TDWKSGDTYQSLSSSSTA---TGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAR 331
T KS T S +T TT E + +P TTP + + +
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 332 EISSPGRPPGLMSPSSGYSSQSETPTPTVSMSL--TLGHLPPPSSSVRVRPVVPERKSSL 389
+ + P +P + + TPT L T P P++ + P PE +
Sbjct: 600 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 659
Query: 390 PPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNP 449
P P PK+ ++PN + + T K T P
Sbjct: 660 TPEEPAPTTPKA---------AAPN---------------TPKEPAPTT--PKEPAPTTP 693
Query: 450 NQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKP 509
+P T + + + + ++ +P ++P +E+ ++ +KP
Sbjct: 694 KEP--APTTPKETAPTTPKGTAPTTLKE--PAPTTPKKPAPKELAPTTTKEPTSTTCDKP 749
Query: 510 PVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDG 569
P + P+ P+E A T+P P L + + T +KP P
Sbjct: 750 ----APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL--- 802
Query: 570 RSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEK 629
+P + P+S A ++ + T + P PE + E +
Sbjct: 803 -APTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP-APTTPETPPPTTSEVSTP 860
Query: 630 KKGKIPPPVPKKPSVLYLPLTS-PTAQ-MEAYVAEPRLPL--SPIITLEEDT---KCPAT 682
K P + K P L++ PT + +E EP +P +P T E T K T
Sbjct: 861 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 920
Query: 683 GDDLQSLGQRVTSTPQADSE 702
DL++ + T+ P+ E
Sbjct: 921 ERDLRTTPETTTAAPKMTKE 940
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 58.9 bits (141), Expect = 2e-08
Identities = 103/468 (22%), Positives = 161/468 (34%), Gaps = 82/468 (17%)
Query: 306 SSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLT 365
SS SL+ S+S +++ S+ + + SSP R +SPS+ + P+P +
Sbjct: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410
Query: 366 LGHLPPPSSSVRVRP------------VVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSP 413
H P P S R R V + K + SP PK R +L +
Sbjct: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP-SPAPKPR-KVELSESEED 468
Query: 414 NLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKS 473
+ S++ + + R + +++ + + +P V ++ R S S+S
Sbjct: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
Query: 474 ------------------------EPEDDIESPEYAEEPRAEEVFTLPERKTKP------ 503
P SP A PR T P R+ P
Sbjct: 529 ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
Query: 504 ----PVAEKPPVARR------PPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQD 553
P PP+ RR P PP P+ A SP PP+ + H+ P Q
Sbjct: 589 RSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP----PPKRRVSHSPPPKQR 644
Query: 554 SYTVVRKPKP---SSFPDGRSPGEST------------APSSLVFTPFASSS-DAFFSGT 597
S V ++ P S G SP ST +PS P SSS G
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
Query: 598 QQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLT-SPTAQM 656
PQ + P P R ++ E + KK P P SV + + S +
Sbjct: 705 SSSPQ---RRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP----QSVRRVSSSRSVSGSP 757
Query: 657 EAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQADSERE 704
E +P P SP+ + T ++ + +P +S++E
Sbjct: 758 EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQE 805
Score = 40.8 bits (94), Expect = 0.004
Identities = 79/334 (23%), Positives = 119/334 (35%), Gaps = 55/334 (16%)
Query: 316 SRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSS 375
SR+ +P + S V S R P + ++S +P+P LP PS
Sbjct: 177 SRSPSPRRRSSPVRRERKRSHSRSPR-------HRTKSRSPSPAPEKKEKTPELPEPSVK 229
Query: 376 VRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKV---SR 432
V+ P V E S TS + K PK +P P+ + + + KT+ SR
Sbjct: 230 VK-EPSVQEATS----TSDILKVPKPE---PIPEPKEPSPEKNSKKEKEKEKTRPRSRSR 281
Query: 433 HHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEE 492
S + + T P + R RS S+S SP PR
Sbjct: 282 SKSRSRTRSRSPSHTRPRR--------------RHRSRSRSY------SPRRRPSPRRRP 321
Query: 493 VFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQ 552
P R+T P PP RR S V + + +S + SS +R P+
Sbjct: 322 S---PRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS------SSSSRSRSPPK 372
Query: 553 DSYTVVRKPKPSSFPDGRSP--GESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGP 610
+ PK +S P ++ S +P P ++ + PQ S
Sbjct: 373 ------KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426
Query: 611 KVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSV 644
+V V P R S + + +K + P P PK V
Sbjct: 427 RVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460
Score = 30.8 bits (68), Expect = 4.5
Identities = 73/406 (17%), Positives = 133/406 (32%), Gaps = 55/406 (13%)
Query: 127 RFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHR 186
++R ++ +DSG++ DE K + + + + + Q+E R
Sbjct: 484 QYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR 543
Query: 187 RQRSKSIS----LRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQ 242
+R +S S R+ P+PP R P S P+ + P S Q
Sbjct: 544 GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTP--SPPPRRRSPSPRRYSPPIQ 601
Query: 243 GHHSSHPDAQGHPAIP--------NHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATG 294
+S P + A P + P + SH + SS T
Sbjct: 602 RRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSH---------SPPPKQRSSPVTKRR 652
Query: 295 TTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSE 354
+ + +GSS S ++ + S R + PP + +S + +
Sbjct: 653 SPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQ 712
Query: 355 TPTPTVSMSLTLGHLPPP-------------------SSSVRVRPVVPERKSSLPPTSPM 395
+P+P+ + P P S SV P +K PP+
Sbjct: 713 SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ 772
Query: 396 EKFPKSRLSFDLPL------TSSP----NLDLSGMSISIRSKTKVSRHHSETNFGVKLAQ 445
+ P + S +P+ T SP N D G + K K +H + K +
Sbjct: 773 SQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGG-KKKKKKKDKKHKKDKKH--KKHK 829
Query: 446 KTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAE 491
K + + + + + + E+ + +PE +E +E
Sbjct: 830 KHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESE 875
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 58.5 bits (140), Expect = 2e-08
Identities = 92/420 (21%), Positives = 145/420 (34%), Gaps = 28/420 (6%)
Query: 274 LTDWKSGDTYQSLSSSSTATGTTVIECTQVQGS-SESLASPSTSRATTPSQLSIEVEARE 332
L D S D Y+ + T +G + E T G +L + +T +P L + +
Sbjct: 925 LPDTGSKDGYKLPWTWDTPSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDT-- 982
Query: 333 ISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVP------ERK 386
SP +P P ++++ PTP+ S + G P +S R + P E
Sbjct: 983 -GSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEAT 1041
Query: 387 SSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISI-------RSKTKVSRHHSETNF 439
S P TSP P SR + DL LT SP+ LS S+ S T + E
Sbjct: 1042 SDAPDTSPPTPDPASRTNPDLILT-SPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTS 1100
Query: 440 GVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPR---AEEVFTL 496
+ P V +SD + S + SP+ + P +
Sbjct: 1101 DPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMA 1160
Query: 497 PERKT--KPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDS 554
P+ T P V P P + H P ++ + PT P ++I H+ +P +
Sbjct: 1161 PDPITTLNPTVTPHFPTTPHPTTTPH-PTTITHSTMIPDPTTTPQPFTTITHSTMIPDPT 1219
Query: 555 YT--VVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKV 612
T +P++ P +P +T P T D + T QP P
Sbjct: 1220 TTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDP--TTTPQPFTTMQPTTMPHP 1277
Query: 613 RVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIIT 672
P + P + P+ P T+P + P +P+IT
Sbjct: 1278 TTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVIT 1337
Score = 35.0 bits (79), Expect = 0.24
Identities = 79/408 (19%), Positives = 132/408 (32%), Gaps = 41/408 (10%)
Query: 309 SLASPSTSRATTPSQL-SIEVEAREISSPGRPPGLMSP--SSGYSSQSETPTPTVSMSLT 365
+L TS +TPS++ S+ + ++ P L + SS S S +P P+ S T
Sbjct: 1093 TLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPT 1152
Query: 366 LGHLPPPSSSVRVRPVVPERKSSLP--PTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSIS 423
P ++ P+ + P PT+P T++P+ S
Sbjct: 1153 T----TPDPTMAPDPITTLNPTVTPHFPTTPHP-------------TTTPHPTTITHSTM 1195
Query: 424 IRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPE 483
I T + + + T QP M + S + P S
Sbjct: 1196 IPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTM 1255
Query: 484 YAEEPRAEEVFTLPERKTKP-------PVAEKPPVARRPPSLVHKPPSVPEEYALTSPTL 536
+ + FT + T P P P P+ P P+ PT
Sbjct: 1256 IPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTT 1315
Query: 537 AMPPRSSIQHARPLPQDSYTVVRKPKPSSF-PDGRSPGESTAPSSLVFTPFASSSDAFFS 595
P ++ P P + + P+S + SP + + ++ A +
Sbjct: 1316 TPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHT 1375
Query: 596 GTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQ 655
T Q P + P + P R S + + + PP + P++ P +P +
Sbjct: 1376 STSQIP---TLEPSPALESSPSRSSTATSMDPLSTE-DFKPPRSQSPNLTPPPTHTPHSA 1431
Query: 656 MEAYVAEPRLPLSPII------TLEEDTKCPATGDDLQSLGQRVTSTP 697
+ V+ L LSP L+ T P G G V TP
Sbjct: 1432 SDLTVSPDPL-LSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTP 1478
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 55.1 bits (131), Expect = 2e-07
Identities = 127/602 (21%), Positives = 191/602 (31%), Gaps = 69/602 (11%)
Query: 105 PSKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTS 164
PS L + + PG + S + Q A LP ST+
Sbjct: 3512 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 3571
Query: 165 SE--GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEG 222
S G ++ I+S S + A + +S + SP + + +L
Sbjct: 3572 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 3631
Query: 223 GSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIP-----NHKDPESTQF--------- 268
+ RP S H ++ PD+ P + +H P ST
Sbjct: 3632 EESTTSHSRPGST--------HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 3683
Query: 269 ---SHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLS 325
S + SG T +LS ST + E T S S + +TT S +
Sbjct: 3684 SGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI- 3742
Query: 326 IEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPER 385
+E R SS G P +SP+S S + + H P S PV
Sbjct: 3743 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 3802
Query: 386 K-SSLPPTSPMEKFP----------KSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSR-- 432
P ++P FP KS + P S + + S R ++ SR
Sbjct: 3803 TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 3862
Query: 433 ---------HHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPE 483
S T G+ A T + P P T L + S+ E ES
Sbjct: 3863 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT---LSPASMTSLGVGE-----ESTT 3914
Query: 484 YAEEPRAEEVFTLPERKTKPPVAEK-PPVARRPPSLVHK---PPSVPEEYALTSPTLAMP 539
+P + P T P ++E+ V P P S PT
Sbjct: 3915 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPT-TFH 3973
Query: 540 PRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFS---- 595
R + H +DS T + ++FP + ++ P++L S F S
Sbjct: 3974 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 4033
Query: 596 -GTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTA 654
GT+ P S G P R+S S E P + +K + Y SP A
Sbjct: 4034 TGTKLSPARST-TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 4092
Query: 655 QM 656
+
Sbjct: 4093 TL 4094
Score = 54.7 bits (130), Expect = 3e-07
Identities = 126/602 (20%), Positives = 191/602 (31%), Gaps = 69/602 (11%)
Query: 105 PSKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTS 164
PS L + + PG + S + Q A LP ST+
Sbjct: 872 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 931
Query: 165 SE--GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEG 222
S G ++ I+S S + A + +S R SP + + +L
Sbjct: 932 SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 991
Query: 223 GSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIP-----NHKDPESTQF--------- 268
+ RP S H ++ PD+ P + +H P ST
Sbjct: 992 EESTTSRSRPGST--------HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 1043
Query: 269 ---SHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLS 325
S + SG T +LS ST + E T + S + +TT S +
Sbjct: 1044 SGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGI- 1102
Query: 326 IEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPER 385
+E R SS G P +SP+S S + + H P S PV
Sbjct: 1103 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 1162
Query: 386 K-SSLPPTSPMEKFP----------KSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSR-- 432
P ++P FP KS + P S + + S R ++ SR
Sbjct: 1163 TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 1222
Query: 433 ---------HHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPE 483
S T G+ A T + P P T L + S+ E ES
Sbjct: 1223 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT---LSPASMTSLGVGE-----ESTT 1274
Query: 484 YAEEPRAEEVFTLPERKTKPPVAEKPPV----ARRPPSLVHKPPSVPEEYALTSPTLAMP 539
+P + P T P ++E+ +R P S PT
Sbjct: 1275 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPT-TFH 1333
Query: 540 PRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFS---- 595
R + H +DS T + ++FP + ++ P++L S F S
Sbjct: 1334 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 1393
Query: 596 -GTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTA 654
GT+ P S G P R+S S E P + +K + Y SP A
Sbjct: 1394 TGTKLSPARST-TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 1452
Query: 655 QM 656
+
Sbjct: 1453 TL 1454
Score = 53.9 bits (128), Expect = 5e-07
Identities = 132/649 (20%), Positives = 206/649 (31%), Gaps = 86/649 (13%)
Query: 105 PSKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTS 164
PS L + + PG + S + Q A LP ST+
Sbjct: 1955 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 2014
Query: 165 SE--GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEG 222
S G ++ I+S S + A + +S + SP + + +L
Sbjct: 2015 SVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 2074
Query: 223 GSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIP-----NHKDPESTQFSHHWYLTDW 277
+ RP S H ++ PD+ P + +H P ST + T
Sbjct: 2075 EESTTSHSRPGST--------HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT- 2125
Query: 278 KSGDTYQSLSS----SSTATGTTVIECTQVQGSSESL---ASPSTSRAT-----TPSQLS 325
SG + +S +S ST T + T + ES +SP ++ T T S
Sbjct: 2126 TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 2185
Query: 326 IEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPER 385
+E R SS G P +SP+S S + + H P S PV
Sbjct: 2186 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 2245
Query: 386 K-SSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLA 444
P ++P FP S + S + S T S H + + G
Sbjct: 2246 TYHRSPGSTPTTHFPASSTTSG----HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 2301
Query: 445 QKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPP 504
+ +P + S + P S + PR+ P T
Sbjct: 2302 SRISPGS-----------TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2350
Query: 505 VAEKPPVARRPPSLVHK--------PPSVPEEYAL-------TSPTLAMP--PRSSIQ-- 545
V E+ +R P H P + EE ++ T P P +S++
Sbjct: 2351 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGE 2410
Query: 546 -----HARP-------LPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAF 593
H+RP +DS T + ++FP + ++ P++L S F
Sbjct: 2411 EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF 2470
Query: 594 FS-----GTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLP 648
S GT P S G P R+S S E P + +K + Y
Sbjct: 2471 PSSSGSTGTTLSPARST-TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 2529
Query: 649 LTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTP 697
SP A + P S ++ E T G + T+TP
Sbjct: 2530 PRSPDATL-----SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTP 2573
Score = 53.5 bits (127), Expect = 7e-07
Identities = 133/621 (21%), Positives = 192/621 (30%), Gaps = 73/621 (11%)
Query: 130 ERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQR 189
E S + P+ SG+T + L ST S S S+ +L ++
Sbjct: 2465 EESTTFPSSSGSTGTTLSPARSTTSG--LVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 2522
Query: 190 SKSI--SLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLC---LSLEHQGH 244
S + S R SP T + S V +E + P S LS
Sbjct: 2523 STTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTS 2582
Query: 245 HSS--HPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQ 302
HSS D PA P + H G T +LS ST + E T
Sbjct: 2583 HSSPGSTDTTLLPASTTTSGPSQESTTSHS-----SPGSTDTALSPGSTTALSFGQESTT 2637
Query: 303 VQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSM 362
S S + +TT S + +E R SS G P +SP+S S + + T
Sbjct: 2638 FHSSPGSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQT 2696
Query: 363 SLTLGHLPPPSSSVRVRPVVPERK-SSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMS 421
H P S PV P ++P FP S + S + S
Sbjct: 2697 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG----HSEKSTIFHSS 2752
Query: 422 ISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIES 481
T S H + + G + +P + S + P S
Sbjct: 2753 PDASGTTPSSAHSTTSGRGESTTSRISPGS-----------TEITTLPGSTTTPGLSEAS 2801
Query: 482 PEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHK--------PPSVPEEYALT- 532
+ PR+ P T V E+ +R P H P + EE
Sbjct: 2802 TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVY 2861
Query: 533 -----SPTLAMPPRSSIQ----------HARP-------LPQDSYTVVRKPKPSSFPDGR 570
S + PRS+ H+RP +DS T + ++FP
Sbjct: 2862 SSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 2921
Query: 571 SPGESTAPSSLVFTPFASSSDAFFS-----GTQQPPQGSVEDEGPKVRVLPERISLQSQE 625
+ ++ P++L S F S GT P S G P R+S S E
Sbjct: 2922 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARST-TSGLVGESTPSRLSPSSTE 2980
Query: 626 EAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDD 685
P + +K + Y SP A + P S ++ E T G
Sbjct: 2981 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATL-----SPATTTSSGVSEESSTSHSQPGST 3035
Query: 686 LQSLGQRVTSTPQADSEREAS 706
+ T+T E AS
Sbjct: 3036 HTTAFPDSTTTSGLSQEPTAS 3056
Score = 48.9 bits (115), Expect = 2e-05
Identities = 91/383 (23%), Positives = 134/383 (34%), Gaps = 63/383 (16%)
Query: 263 PESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQ-----VQGSSESLASPSTSR 317
P STQ LT G+ + SSS +TGTT+ V S+ S SPS++
Sbjct: 2447 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE 2506
Query: 318 ATT----PSQLSI-EVEAREISSPGRPPGLMSP----SSGYSSQS--------------- 353
TT P+ S+ E +SP P +SP SSG S +S
Sbjct: 2507 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAF 2566
Query: 354 --ETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTS 411
T TP +S T H P S+ ++P ++ P+ S S D L+
Sbjct: 2567 PDSTTTPGLSRHSTTSHSSPGSTDT---TLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2623
Query: 412 SPNLDLS-GMSISIRSKTKVSRH-----HSETNFGVKLAQKTNPNQPIMPMVTQSDLRSV 465
LS G + + S H S T+ G+ A + P T
Sbjct: 2624 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT------- 2676
Query: 466 RLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSV 525
L S + P ES + P + P PV E R P S +
Sbjct: 2677 -LSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS------TP 2729
Query: 526 PEEYALTSPTLAMPPRSSIQHARP-----LPQDSYTVVRKPKPSSFPDGRSPGE---STA 577
+ +S T +S+I H+ P P +++ + S SPG +T
Sbjct: 2730 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT-SGRGESTTSRISPGSTEITTL 2788
Query: 578 PSSLVFTPFASSSDAFFSGTQQP 600
P S + +S F+S + P
Sbjct: 2789 PGSTTTPGLSEASTTFYSSPRSP 2811
Score = 47.0 bits (110), Expect = 6e-05
Identities = 128/574 (22%), Positives = 189/574 (32%), Gaps = 80/574 (13%)
Query: 162 STSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSP-PTRSVS--LVKDE--- 215
ST+S GS S+ SA R + S ++ +P P RS + LV++
Sbjct: 1856 STTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAY 1915
Query: 216 ---PGL-----LPEGGSALPKDQRPKSLCLSLEHQ-GHHSSHPDAQGHPAIPNHKDPEST 266
PG PE +A + + ++ S H S A H P ST
Sbjct: 1916 HSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGST 1975
Query: 267 QFSHHWYLTDWKSGDTYQSLSSSST--ATGTTVIECTQVQGSSESLASPSTSRATTPSQL 324
+H + + SG + +S +S S+ ATGT V+ + S S +TT
Sbjct: 1976 ATTH-FPDSSTTSGRSEESTASHSSQDATGTIVLP-------ARSTTSVLLGESTTSPIS 2027
Query: 325 SIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPE 384
S +E + PGL S+ + S +P T+S + T SS V
Sbjct: 2028 SGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAST------TSSGVSEESTT-- 2079
Query: 385 RKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHS----ETNFG 440
S P ++ FP S T++P L S+ + H S +T
Sbjct: 2080 -SHSRPGSTHTTAFPDS--------TTTPGL----------SRHSTTSHSSPGSTDTTLL 2120
Query: 441 VKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERK 500
+ P+Q + L S + ES + P + P+
Sbjct: 2121 PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 2180
Query: 501 TKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTL-----AMPPRSSIQHARPLPQDSY 555
T + E + R S P + + TSP L A + H P P +
Sbjct: 2181 TSSGIVE---ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 2237
Query: 556 T------VVRKPKPSSFPDGRSPGESTAPS-SLVFTPFASSSDAFFSGTQQPPQGSVEDE 608
T P S P P ST S T F SS DA SGT P +
Sbjct: 2238 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA--SGT--TPSSAHSTT 2293
Query: 609 GPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLS 668
+ RIS S E P + + + Y SPT + P S
Sbjct: 2294 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL-----SPASMTS 2348
Query: 669 PIITLEEDTKCPATGDDLQSLGQRVTSTPQADSE 702
+ E T G ++ T+TP E
Sbjct: 2349 LGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 2382
Score = 44.3 bits (103), Expect = 4e-04
Identities = 158/725 (21%), Positives = 234/725 (32%), Gaps = 101/725 (13%)
Query: 19 ESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVSLNKVPPLVPKEAATLLVA 78
EST S S G T P +T+ E+ + S S + L P +
Sbjct: 3275 ESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT-----LSPGSTTASSLG 3329
Query: 79 RDNPAGCSGSAGYPERLIQQRHMPERPSKIGLL--------TSGTSRLETGPGGASRFRE 130
++ SG L+ P+ + GLL ++G+ P G++ +
Sbjct: 3330 PESTTFHSGPGSTETTLL-----PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG 3384
Query: 131 RSL---SVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRR 187
S S P TT A ST+S GS S+ SA R
Sbjct: 3385 ESTTFQSWPNSKDTTPAP------PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 3438
Query: 188 QRSKSISLRKAKKKPSP-PTRSVS--LVKDE------PGL-----LPEGGSALPKDQRPK 233
+ S ++ +P P RS + LV++ PG PE + + +
Sbjct: 3439 EESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEEST 3498
Query: 234 SLCLSLEHQ-GHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSST- 291
+ S H S A H P ST +H + + SG + +S +S S+
Sbjct: 3499 TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH-FPDSSTTSGRSEESTASHSSQ 3557
Query: 292 -ATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYS 350
ATGT V+ + S S +TT S +E + PGL S+ +
Sbjct: 3558 DATGTIVLP-------ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH 3610
Query: 351 SQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLT 410
S +P T+S + T SS V S P ++ FP S T
Sbjct: 3611 SSPRSPATTLSPAST------TSSGVSEESTT---SHSRPGSTHTTAFPDS--------T 3653
Query: 411 SSPNLDL-SGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRS 469
++P L S S S T + + T + T + + S L
Sbjct: 3654 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSH-------SSSGSTDTALSP 3706
Query: 470 VSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEY 529
S + ES + P + P+ T + E + R S P +
Sbjct: 3707 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE---ASTRVHSSTGSPRTTLSPA 3763
Query: 530 ALTSPTL-----AMPPRSSIQHARPLPQDSYT------VVRKPKPSSFPDGRSPGESTAP 578
+ TSP L A + H P P + T P S P P ST
Sbjct: 3764 SSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 3823
Query: 579 S-SLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPP 637
S T F SS DA SGT P + + RIS S E P
Sbjct: 3824 GHSEKSTIFHSSPDA--SGT--TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG 3879
Query: 638 VPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTP 697
+ + + Y SPT + P S + E T G ++ T+TP
Sbjct: 3880 LSEASTTFYSSPRSPTTTL-----SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 3934
Query: 698 QADSE 702
E
Sbjct: 3935 GLSEE 3939
Score = 38.9 bits (89), Expect = 0.017
Identities = 82/379 (21%), Positives = 137/379 (36%), Gaps = 50/379 (13%)
Query: 259 NHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRA 318
+H P ST + T + T LS TA+ ++ QGS+E+ SP ++ A
Sbjct: 3028 SHSQPGST------HTTAFPDSTTTSGLSQEPTASHSS-------QGSTEATLSPGSTTA 3074
Query: 319 TTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQS-ETPTPTVSMSLTL-GHLPPPSSSV 376
++ Q S SSPG + P +S E TPT S + +L L P SS+
Sbjct: 3075 SSLGQQSTTFH----SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS 3130
Query: 377 RVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPL--------TSSPNLDLSGMSISI-RSK 427
S P +S P + + + +S+P S S ++ RS+
Sbjct: 3131 AGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 3190
Query: 428 TKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSV----SKSEPEDDIESPE 483
+ H S G L + ++ T S + S + S + +S
Sbjct: 3191 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 3250
Query: 484 YAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSS 543
+ PR+ + P T V+E+ + P H + + T P ++ S+
Sbjct: 3251 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH---TTAFPGSTTMPGVSQ--EST 3305
Query: 544 IQHARP-------LPQDSYTVVRKPKPSSFPDGRSPGEST-APSSLVFTPFASSSDAFFS 595
H+ P P + P+ ++F G E+T P + + +S S
Sbjct: 3306 ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 3365
Query: 596 GTQQP-----PQGSVEDEG 609
T P P GS +G
Sbjct: 3366 STGSPHTTLSPAGSTTRQG 3384
Score = 38.1 bits (87), Expect = 0.028
Identities = 88/393 (22%), Positives = 138/393 (35%), Gaps = 47/393 (11%)
Query: 249 PDAQGHPAIPNHKD-PESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECT---QVQ 304
PDA PA E + SH + G T+ + ST T E T Q
Sbjct: 1450 PDATLSPATTTSSGVSEESSTSHS------QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQ 1503
Query: 305 GSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQS-ETPTPTVSMS 363
GS+E+ SP ++ A++ Q S SSPG + P +S E TPT S +
Sbjct: 1504 GSTEATLSPGSTTASSLGQQSTTFH----SSPGDTETTLLPDDTITSGLVEASTPTHSST 1559
Query: 364 LTL-GHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPL--------TSSPN 414
+L L P SS+ S P +S P + + + +S+P
Sbjct: 1560 GSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPT 1619
Query: 415 LDLSGMSISI-RSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSV--- 470
S S ++ RS+ + H S G L + ++ T S + S +
Sbjct: 1620 THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 1679
Query: 471 -SKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEY 529
S + +S + PR+ + P T V+E+ + P H +
Sbjct: 1680 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH---TTAFPG 1736
Query: 530 ALTSPTLAMPPRSSIQHARPLPQDS-----YTVVRKPKPSSFPDGRSPGESTA---PSSL 581
+ T P ++ S+ H+ P D+ T P S SPG + P +
Sbjct: 1737 STTMPGVSQ--ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNT 1794
Query: 582 VFTPFASSSDAFFSGTQQP-----PQGSVEDEG 609
+ +S S T P P GS +G
Sbjct: 1795 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG 1827
Score = 36.2 bits (82), Expect = 0.11
Identities = 134/623 (21%), Positives = 209/623 (33%), Gaps = 98/623 (15%)
Query: 20 STFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVSLNKVPPLVPKEAATLLVAR 79
ST + S G T +TP++++ + E+ + SW S + P P A
Sbjct: 4192 STPTHSSTGSLHTTLTPASSTSTGLQEES----TTFQSWPSSSDTTPSPPSTTAV----- 4242
Query: 80 DNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLETGPG--GASRFRERSL-SVP 136
P S + H + +G T+ + + PG G + F RS SV
Sbjct: 4243 --PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT-VHSSPGATGTALFPTRSATSVL 4299
Query: 137 TDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLR 196
TT + E ALP ++T+ A LS + + RS +L
Sbjct: 4300 VGEPTTS---PISSGSTETTALPGSTTT----------AGLSEKSTTFYSSPRSPDTTLS 4346
Query: 197 KAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPA 256
A S + + PG + +A P + S E HSS P +
Sbjct: 4347 PASTTSSGVSEESTTSHSRPGSMHT--TAFPSSTTMPGV--SQESTASHSS-PGSTDTTL 4401
Query: 257 IPNHKD-----PESTQF------SHHWYLTDWKSGDTYQSLSS---SSTATGTTVIE--- 299
P PEST F + L D + S+ SST + T +
Sbjct: 4402 SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG 4461
Query: 300 CTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSS------QS 353
T QG S + S S+ TTP+ + E+S+ +P++ +S+ +S
Sbjct: 4462 STTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 4521
Query: 354 ETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKS--SLPPTSPMEKFPKSRLSFDLPLTS 411
E T S + P P+ S +V E + S P ++ FP+S + S
Sbjct: 4522 EESTTVHSSPVATATTPSPARST-TSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEES 4580
Query: 412 SPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVS 471
+ + + +IS T + T++ ++P S S R +
Sbjct: 4581 TTSHSSTTHTISSAPSTTSALVEEPTSY------HSSPGSTATTHFPDSSTTSGRSEEST 4634
Query: 472 KSEPEDDI-----------------ESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARR 514
S D ES + E LP T P ++EK
Sbjct: 4635 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 4694
Query: 515 PPSLVHKPPSVP-EEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPG 573
PS S P ++ +S TL S+ H+ P+ P P+
Sbjct: 4695 SPS------STPTTHFSASSTTLGRSEESTTVHSSPV-----ATATTPSPARSTTSGLVE 4743
Query: 574 ESTA----PSSLVFTPFASSSDA 592
ESTA P S F SS A
Sbjct: 4744 ESTAYHSSPGSTQTMHFPESSTA 4766
Score = 33.1 bits (74), Expect = 0.91
Identities = 79/362 (21%), Positives = 122/362 (33%), Gaps = 72/362 (19%)
Query: 260 HKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLAS-PSTSRA 318
H P ST +H S+SST G + E T V S + A+ PS +R+
Sbjct: 4693 HSSPSSTPTTH---------------FSASSTTLGRSE-ESTTVHSSPVATATTPSPARS 4736
Query: 319 TTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRV 378
TT +E SSPG + P S +S + T S S T + P S+
Sbjct: 4737 TTSGL--VEESTAYHSSPGSTQTMHFPESSTASGRSEESRT-SHSSTTHTISSPPSTTSA 4793
Query: 379 RPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETN 438
P S P + FP+S + S RS+ + H S
Sbjct: 4794 LVEEPTSYHSSPGSIATTHFPES------------------STTSGRSEESTASHSS--- 4832
Query: 439 FGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPE 498
TN P+ T S + ES + P + E TL
Sbjct: 4833 ------PDTNGITPLPAHFTTSGRIA---------------ESTTFYISPGSMET-TLAS 4870
Query: 499 RKTKPPVAEKPPV---ARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSY 555
T P ++ K + + R P P S+ PT ++ ++ H P +
Sbjct: 4871 TATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPT-SLYSQAESTHTTAFPASTT 4929
Query: 556 TVVRKPKPSSFPDGRSPGEST-APSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRV 614
T + ++F E+T +P S+ + FA F+ P ++ P
Sbjct: 4930 TSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQE----FTTPHSQPGSALSTVSPASTT 4985
Query: 615 LP 616
+P
Sbjct: 4986 VP 4987
Score = 32.7 bits (73), Expect = 1.2
Identities = 37/139 (26%), Positives = 52/139 (37%), Gaps = 7/139 (5%)
Query: 280 GDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRP 339
G T +LS +T + E T S + TT S L +E SS G P
Sbjct: 344 GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGL-LEASTPVHSSTGSP 402
Query: 340 PGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFP 399
+SPSS + + E PT S + P PS + + S P ++P F
Sbjct: 403 HTTLSPSSSTTHEGE-PTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFS 461
Query: 400 KSRLSF-----DLPLTSSP 413
S + P+ SSP
Sbjct: 462 ASSTTLGHSEESTPVHSSP 480
Score = 31.6 bits (70), Expect = 2.7
Identities = 117/527 (22%), Positives = 170/527 (32%), Gaps = 99/527 (18%)
Query: 130 ERSLSVPTDSGTTDVDYDEEQKANEACA-------LPFASTSSEGSNSADNIASLSAQQE 182
E S + P+ SG+T + L +ST + + SLS +
Sbjct: 4022 EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 4081
Query: 183 AQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPG-----LLPEGGSALPKDQRPKSLCL 237
+ RS +L A S + S +PG P+ + Q P +
Sbjct: 4082 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTT--- 4138
Query: 238 SLEHQGHH-------SSHPDAQGHPAIPNHKDPESTQFSHHWYLTD--------WKSGDT 282
S QG S+ + G + H P T+ + L D S T
Sbjct: 4139 SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT---LLPDDTITSGLVEASTPT 4195
Query: 283 YQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGL 342
+ S S T T +Q S + S +S TTPS S E+S
Sbjct: 4196 HSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVS-------- 4247
Query: 343 MSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRP------VVPERKSSL-----PP 391
++ +S S TPT S S T S++V P + P R ++ P
Sbjct: 4248 ---TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT 4304
Query: 392 TSPMEK-------FPKSRLSFDLPLTS--------SPNLDLSGMS-----ISIRSKTKVS 431
TSP+ P S + L S SP+ LS S +S S T S
Sbjct: 4305 TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 4364
Query: 432 RHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRS--------VRLRSVSKSEPEDDIESPE 483
R S + P+ MP V+Q S L S + ES
Sbjct: 4365 RPGS-------MHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTT 4417
Query: 484 YAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSS 543
+ P + E LP+ T + E A P VH P + SP + +
Sbjct: 4418 FHSSPGSTETTLLPDNTTASGLLE----ASTP---VHSSTGSP--HTTLSPAGSTTRQGE 4468
Query: 544 IQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSS 590
+ P T P +S S +PSS T F++SS
Sbjct: 4469 STTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS 4515
Score = 30.4 bits (67), Expect = 5.9
Identities = 80/373 (21%), Positives = 121/373 (32%), Gaps = 45/373 (12%)
Query: 9 SVPSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVSLNKVPPLV 68
++P S P S ST++ + T ++ S + + ++ + +S V+ P
Sbjct: 4675 ALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS-- 4732
Query: 69 PKEAATLLVARDNPAGCSGSAGYPERLIQQRHMPERPSKIGLL-------TSGTSRLETG 121
P + T + ++ A S Q H PE + G +S T + +
Sbjct: 4733 PARSTTSGLVEESTAYHSSPGS-----TQTMHFPESSTASGRSEESRTSHSSTTHTISSP 4787
Query: 122 PGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQ 181
P S E S + G+ + E + ST+S S + I L A
Sbjct: 4788 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEE--STASHSSPDTNGITPLPAHF 4845
Query: 182 EAQHRRQRSKSI---------SLRKAKKKPSPPTRSVSLVKD----EPGLLPEGGSALPK 228
R S + +L P +S L + L P ++
Sbjct: 4846 TTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSI 4905
Query: 229 DQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSS 288
P SL E S+H A + EST F K G T +LS
Sbjct: 4906 SGEPTSLYSQAE-----STHTTAFPASTTTSGLSQESTTFHS-------KPGSTETTLSP 4953
Query: 289 SSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLM---SP 345
S T + E T S S + +TT LS E SSPG S
Sbjct: 4954 GSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLS-EESTTFYSSPGSTETTAFSHSN 5012
Query: 346 SSGYSSQSETPTP 358
+ SQ TP P
Sbjct: 5013 TMSIHSQQSTPFP 5025
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 54.7 bits (130), Expect = 3e-07
Identities = 126/602 (20%), Positives = 191/602 (31%), Gaps = 69/602 (11%)
Query: 105 PSKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTS 164
PS L + + PG + S + Q A LP ST+
Sbjct: 359 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 418
Query: 165 SE--GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEG 222
S G ++ I+S S + A + +S R SP + + +L
Sbjct: 419 SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 478
Query: 223 GSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIP-----NHKDPESTQF--------- 268
+ RP S H ++ PD+ P + +H P ST
Sbjct: 479 EESTTSRSRPGST--------HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT 530
Query: 269 ---SHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLS 325
S + SG T +LS ST + E T + S + +TT S +
Sbjct: 531 SGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGI- 589
Query: 326 IEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPER 385
+E R SS G P +SP+S S + + H P S PV
Sbjct: 590 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEEST 649
Query: 386 K-SSLPPTSPMEKFP----------KSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSR-- 432
P ++P FP KS + P S + + S R ++ SR
Sbjct: 650 TYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 709
Query: 433 ---------HHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPE 483
S T G+ A T + P P T L + S+ E ES
Sbjct: 710 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT---LSPASMTSLGVGE-----ESTT 761
Query: 484 YAEEPRAEEVFTLPERKTKPPVAEKPPV----ARRPPSLVHKPPSVPEEYALTSPTLAMP 539
+P + P T P ++E+ +R P S PT
Sbjct: 762 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPT-TFH 820
Query: 540 PRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFS---- 595
R + H +DS T + ++FP + ++ P++L S F S
Sbjct: 821 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 880
Query: 596 -GTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTA 654
GT+ P S G P R+S S E P + +K + Y SP A
Sbjct: 881 TGTKLSPARST-TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 939
Query: 655 QM 656
+
Sbjct: 940 TL 941
Score = 38.1 bits (87), Expect = 0.028
Identities = 88/393 (22%), Positives = 138/393 (35%), Gaps = 47/393 (11%)
Query: 249 PDAQGHPAIPNHKD-PESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECT---QVQ 304
PDA PA E + SH + G T+ + ST T E T Q
Sbjct: 937 PDATLSPATTTSSGVSEESSTSHS------QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQ 990
Query: 305 GSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQS-ETPTPTVSMS 363
GS+E+ SP ++ A++ Q S SSPG + P +S E TPT S +
Sbjct: 991 GSTEATLSPGSTTASSLGQQSTTFH----SSPGDTETTLLPDDTITSGLVEASTPTHSST 1046
Query: 364 LTL-GHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPL--------TSSPN 414
+L L P SS+ S P +S P + + + +S+P
Sbjct: 1047 GSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPT 1106
Query: 415 LDLSGMSISI-RSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSV--- 470
S S ++ RS+ + H S G L + ++ T S + S +
Sbjct: 1107 THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 1166
Query: 471 -SKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEY 529
S + +S + PR+ + P T V+E+ + P H +
Sbjct: 1167 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTH---TTAFPG 1223
Query: 530 ALTSPTLAMPPRSSIQHARPLPQDS-----YTVVRKPKPSSFPDGRSPGESTA---PSSL 581
+ T P ++ S+ H+ P D+ T P S SPG + P +
Sbjct: 1224 STTMPGVSQ--ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNT 1281
Query: 582 VFTPFASSSDAFFSGTQQP-----PQGSVEDEG 609
+ +S S T P P GS +G
Sbjct: 1282 TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG 1314
Score = 31.6 bits (70), Expect = 2.7
Identities = 126/624 (20%), Positives = 210/624 (33%), Gaps = 76/624 (12%)
Query: 20 STFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVSLNKVPPLVPKEAATLLVAR 79
ST + S G T +TP++++ + E+ + SW S + P P A
Sbjct: 1039 STPTHSSTGSLHTTLTPASSTSAGLQEES----TTFQSWPSSSDTTPSPPGTTAA----- 1089
Query: 80 DNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLETGPG--GASRFRERSL-SVP 136
P S + H + +G T+ + + PG G + F RS SV
Sbjct: 1090 --PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT-VHSSPGATGTALFPTRSATSVL 1146
Query: 137 TDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLR 196
TT + E ALP ++T+ A LS + + RS +L
Sbjct: 1147 VGEPTTS---PISSGSTETTALPGSTTT----------AGLSEKSTTFYSSPRSPDTTLS 1193
Query: 197 KAKKKPSPPTRSVSLVKDEPGLLPE----GGSALPKDQRPKSLCLSLEHQGHHSSHPDAQ 252
A S + + PG G + +P + + S + P +
Sbjct: 1194 PASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST 1253
Query: 253 -----GHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSS---SSTATGTTVIE---CT 301
G + H P ST+ + L D + S+ SST + T + T
Sbjct: 1254 TASSLGPESTTFHSSPGSTETT---LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGST 1310
Query: 302 QVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVS 361
QG S + S +S+ T P+ + E+S+ +P++ +S+ S T S
Sbjct: 1311 TRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR--S 1368
Query: 362 MSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMS 421
T H P +++ P + ++ P S + P +S+ SG S
Sbjct: 1369 EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESST----ASGRS 1424
Query: 422 ISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPED--DI 479
R+ HS T + T P S S+ +S
Sbjct: 1425 EESRTS------HSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSE 1478
Query: 480 ESPEYAEEPRAEEVFTLPER-KTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAM 538
ES P + LP T +AE + P S+ A T+ T +
Sbjct: 1479 ESTASHSSPDTNGITPLPAHFTTSGRIAES-------TTFYISPGSMETTLASTATTPGL 1531
Query: 539 PPRSSIQHARPLPQDSYTVVRKPKP--------SSFPDGRSPGESTAPSSLVFTPFASSS 590
+S+I + L + T P P SS G + +T +S FT S+
Sbjct: 1532 SAKSTILYTSDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVST 1591
Query: 591 DAFFSGTQQPPQGSVEDEGPKVRV 614
++ + + P+ G V+V
Sbjct: 1592 ESLETLAPETPEKLNATLGMTVKV 1615
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 53.9 bits (128), Expect = 5e-07
Identities = 79/368 (21%), Positives = 136/368 (36%), Gaps = 70/368 (19%)
Query: 338 RPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEK 397
RPPG PS + Q P T + ++L + P S + V P ++ ++
Sbjct: 789 RPPG---PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNH 845
Query: 398 FPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMV 457
F +SF+ P + +PN G +S N G + + P++ +
Sbjct: 846 FSGHGMSFNAPFSGAPN----GNQMSCGQ-----------NPGFPVNKDVTLTSPLLVNL 890
Query: 458 TQSDLRSVRLRSVSKSEPEDDIESPEYAEEPR-----AEEVFTLPERKTKPPVAEKPPV- 511
QSD+ + V+ + + P+ + PR +++ T R A++PP+
Sbjct: 891 LQSDISAGHF-GVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLP 949
Query: 512 ----------ARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKP 561
+ P ++PP P + P MPP+ +QH P PQ ++P
Sbjct: 950 GEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQ-LMQHVAPPPQPPQ---QQP 1005
Query: 562 KPSSFPDGRSPGESTAPSS-------------LVFTPFASSSDAFFSGTQQPPQGSVEDE 608
+P P + P + P S L+ S S PP+G + +
Sbjct: 1006 QP-QLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPD 1064
Query: 609 GPKVRV-----LPERISLQSQEEAEKKKGKIPPPVPKK---PSVLYLPLTSPTAQMEAYV 660
++ + +P +SLQ PP P K P + PL S + +M Y
Sbjct: 1065 SQRMPMQQSGSVPVMVSLQGPASV--------PPSPDKQRMPMPVNTPLGSNSRKM-VYQ 1115
Query: 661 AEPRLPLS 668
P+ P S
Sbjct: 1116 ESPQNPSS 1123
Score = 42.0 bits (97), Expect = 0.002
Identities = 80/377 (21%), Positives = 136/377 (36%), Gaps = 70/377 (18%)
Query: 304 QGSSESLASPSTSRA--------TTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSET 355
+ S + L +P T A P + I ++ +S + P + GY SQ
Sbjct: 924 KNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLD----NSGPKLPEFSNRPPGYPSQPVE 979
Query: 356 PTPTVSMSLTL-GHLPPPSS--SVRVRPVVPERKSSLPPTSP-----------------M 395
P M L H+ PP + +P +P+++ PP+ P M
Sbjct: 980 QRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMM 1039
Query: 396 EKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKL----AQKTNPNQ 451
++ PKS + L S N+ ++ S+ + V L + +P++
Sbjct: 1040 QQDPKS-----VRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDK 1094
Query: 452 PIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPV 511
MPM + L S + V + P++ SP E+ +LPE +E P V
Sbjct: 1095 QRMPMPVNTPLGSNSRKMVYQESPQNPSSSP-------LAEMASLPEASG----SEAPSV 1143
Query: 512 ARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRS 571
P ++ + +T P P S+ Q A P Q + FP+ +
Sbjct: 1144 PGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATP-QQPPVNSLPSSHGHHFPNVAA 1202
Query: 572 PGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKK 631
P +++ P TP +S ++ T S E P ISL +
Sbjct: 1203 PTQTSRPK----TPNRASPRPYYPQTPNNRPPSTE---------PSEISLSPERLNASIA 1249
Query: 632 GKIPP----PVPKKPSV 644
G PP P+P +P++
Sbjct: 1250 GLFPPQINIPLPPRPNL 1266
Score = 30.8 bits (68), Expect = 4.5
Identities = 35/154 (22%), Positives = 53/154 (34%), Gaps = 16/154 (10%)
Query: 494 FTLPERKTKPPVAEKPPVARRPPSLVHK-PPSVPEEYALTSPTLAMPPRSSIQHARPLPQ 552
FT P+ K+ + P + P L +K P S P + SP + + Q P P
Sbjct: 399 FTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPP 458
Query: 553 DSYTVVRKPKPSSFPDG-RSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPK 611
+ P P F SPG + P F QQPP + P
Sbjct: 459 QN-----NPLPQGFQQPVSSPGRNPMVQQGNVPP------NFMVMQQQPPNQGPQSLHPG 507
Query: 612 VRVLPERIS---LQSQEEAEKKKGKIPPPVPKKP 642
+ +P+R+ Q +G++P P
Sbjct: 508 LGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTP 541
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 53.5 bits (127), Expect = 7e-07
Identities = 94/430 (21%), Positives = 149/430 (34%), Gaps = 47/430 (10%)
Query: 282 TYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPP- 340
T ++S+ AT V V + ++A+ S+ T P+ + + + G P
Sbjct: 897 TAAAVSAPERATVPAVT--VSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPE 954
Query: 341 -GLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFP 399
++ + + + TP V+ + T+ H P + VR PE +S P + P
Sbjct: 955 WAALAITVPITEEDGTPEGPVTPATTV-HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013
Query: 400 KSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQ 459
S + +P P + V T+ + P P + T
Sbjct: 1014 TSPAAA-VPTPEEPTSPAAA----------VPPPEEPTSPAAAVPTPEEPTSPAAAVPTP 1062
Query: 460 SDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFT-LPERKTKPPVAEKPPVARRPPSL 518
+ S + EP + EEP + PE T P A P P+
Sbjct: 1063 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122
Query: 519 VHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTV-VRKPKPSSFPDGRSPGESTA 577
P P A PT P + A P P++S + V P P ES +
Sbjct: 1123 AVPTPEEPASPAAAVPTPEEPAFPA--PAVPTPEESASAAVAVPTPE---------ESAS 1171
Query: 578 PSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPP 637
P++ V TP S+S A T + P P V + + EE +P
Sbjct: 1172 PAAAVPTPAESASFAAVVATLEEPTS------PAASVPTPAAMVATLEEFTSPAASVP-- 1223
Query: 638 VPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTP 697
++P+ L +++P EP P + + TLEE T A + L S P
Sbjct: 1224 TSEEPASLAAAVSNPE--------EPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVP 1275
Query: 698 QADSEREASP 707
E ASP
Sbjct: 1276 --TPEEPASP 1283
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 53.1 bits (126), Expect = 9e-07
Identities = 99/401 (24%), Positives = 142/401 (35%), Gaps = 54/401 (13%)
Query: 284 QSLSSSSTATGTTVIECTQVQGSSESLASPSTSR----------ATTPSQLSIEV--EAR 331
Q+ SSS+TA GT++ T +GS+ + P ++R +TTP SI V
Sbjct: 1078 QASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTE 1137
Query: 332 EISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTL------GHLPPPSSSVRVRPVVPER 385
SSP G P+S S+ TP ++ +S TL L + +
Sbjct: 1138 ASSSPTTAEGTSIPTSP-PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196
Query: 386 KSSLPPTSPMEKFPKSRL-SFDLPLTSSP--NLDLSGMSISIRSKTKVSRHHSETNFGVK 442
SS PPT+ + P S PLTS P + ++ S S + V T
Sbjct: 1197 ASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAET 1256
Query: 443 LAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTK 502
+ T +P T S+ S L S+ S P A + T P TK
Sbjct: 1257 SSSPTTAEGTSLPTSTTSE-GSTLLTSIP--------VSTTLVTSPEASTLLTTPV-DTK 1306
Query: 503 PPVAEKPPVARRP--------PSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDS 554
PV V+ P P+ + P + TL SI P+ +S
Sbjct: 1307 GPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPV-DNS 1365
Query: 555 YTVVRKPKPSSFP---DGRS-----PGESTAPSSLV---FTPFASSSDAFFSGT--QQPP 601
V + S P +G S P E T P + + TP SS + S T
Sbjct: 1366 TPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTST 1425
Query: 602 QGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKP 642
G+ E E IS+ + +E K PV P
Sbjct: 1426 PGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTP 1466
Score = 53.1 bits (126), Expect = 9e-07
Identities = 161/734 (21%), Positives = 252/734 (34%), Gaps = 135/734 (18%)
Query: 1 MESMGMVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSA-------TSQSNQVNENGKNPS 53
+ SM + + +S T ST TY S+ TS G P
Sbjct: 3283 LTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPL 3342
Query: 54 CGNSWVSLNKVPPLVPKEAATLL---VARDNPAGCSGSAGYPERLIQQRHMPERPSKIGL 110
S+ P+V EA+TL V P S A + +P G
Sbjct: 3343 TNMSF----STTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGT 3398
Query: 111 LTSGTSRLETGPGGASRFRERSLSVPTDSGT---TDVDYDEEQKANEACALPFASTSSEG 167
+ + T P +S S + P DS T T + E +LP ST+SEG
Sbjct: 3399 TPLASMPVSTTPVVSSEVNTLS-TTPVDSNTLVTTSTEASSSPTIAEGTSLP-TSTTSEG 3456
Query: 168 SNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALP 227
S +I LS A S++ +L S P + S P
Sbjct: 3457 STPL-SIMPLSTTPVAS-----SEASTLSTTPVDTSTPVTTSS----------------P 3494
Query: 228 KDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLS 287
+ P + ++ P ST LT+ T + S
Sbjct: 3495 TNSSPTTAEVT----------------------SMPTSTAGEGSTPLTNMPVSTTPVASS 3532
Query: 288 SSSTATGTTVIECTQVQGSSESLASPSTSRATT-----PSQLSIEVEAREISSPGRPPGL 342
+ST + T V T V SS++ +SP+T + TT PS+ S +
Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT------------ 3580
Query: 343 MSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSR 402
M SS Y + SE TP+ S R PV +S+ PT P
Sbjct: 3581 MLLSSTYVTSSEASTPST------------PSVDRSTPVTTSTQSNSTPTPPE------- 3621
Query: 403 LSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDL 462
LP+ S+P+ + ++I S T V+ + T T P P++T + +
Sbjct: 3622 -VITLPM-STPSEVSTPLTIMPVSTTSVTISEAGT-------ASTLPVDTSTPVITSTQV 3672
Query: 463 RSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKP 522
S + + P I +P P + T+P T+ +E ++ PS+V
Sbjct: 3673 SSSPVTPEGTTMP---IWTPSEGSTP----LTTMPVSTTRVTSSEGSTLS--TPSVVTST 3723
Query: 523 PSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKP-SSFPDGRSPGESTAPSSL 581
P A++S S+ + T++ P + FP+ +P + +S+
Sbjct: 3724 PVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSM 3783
Query: 582 VFTPFA--SSSDAFFSGTQQPPQGSVEDEGPKV-RVLPERISLQSQEEAEKKKGKIPPPV 638
T + SSS GT P + + + VL IS+ S EA PP
Sbjct: 3784 SMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTL--STPPGD 3841
Query: 639 PKKPSVLYLPLTSPTAQMEAYVAEPRLPL-----SPIITLEEDTKCPATGDDLQSLGQRV 693
P L + + + A V R+ + +P+ TL T P + G +
Sbjct: 3842 TSTP--LLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFP-----GASI 3894
Query: 694 TSTPQADSEREASP 707
STP D+ +P
Sbjct: 3895 ASTPPLDTSTTFTP 3908
Score = 47.4 bits (111), Expect = 5e-05
Identities = 105/452 (23%), Positives = 161/452 (35%), Gaps = 63/452 (13%)
Query: 287 SSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPS 346
S ST + T V S+ S S + +TP S E + +S G +PS
Sbjct: 3101 SEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS 3160
Query: 347 SGYSSQSETPTPTV----SMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSR 402
G + + P T+ S TL P +S+ PV +++ T+ P S
Sbjct: 3161 EGSTPLTYMPVSTMLVVSSEDSTLSATPVDTST----PVTTSTEATSSTTAEGTSIPTST 3216
Query: 403 LSFDL-PLTSSP--NLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQ 459
S + PLTS P N ++ SI S T V + T + MP T
Sbjct: 3217 PSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTP 3276
Query: 460 SD----LRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRP 515
S+ L S+ + + + + E S A+ + V T + + PP+A+ +
Sbjct: 3277 SEGSTPLTSMPVSTTTVASSETSTLSTTPAD--TSTPVTTYSQASSSPPIADGTSM---- 3330
Query: 516 PSLVHKPPSVPEEYALTSPTLAMPP--RSSIQHARPLPQDSYTVVRKPKPSSFP------ 567
P+ + S P LT+ + + P S P D+ T V +S
Sbjct: 3331 PTSTYSEGSTP----LTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEG 3386
Query: 568 ---DGRSPGESTAPSS---LVFTPFASSSDAFFSGTQQPPQGSV--EDEGPKVRVLPERI 619
SP E T P + + TP SS S T V E + E
Sbjct: 3387 TSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT 3446
Query: 620 SLQSQEEAEKKKGKIPPPVPKKPSVLYLPL-TSPTAQMEAYV--AEPRLPLSPIITLEED 676
SL + +E G P + +PL T+P A EA P +P+ T
Sbjct: 3447 SLPTSTTSE---GSTPLSI--------MPLSTTPVASSEASTLSTTPVDTSTPVTTSSPT 3495
Query: 677 TKCPATGDDLQSLGQRVTSTPQADSEREASPL 708
P T + VTS P + + ++PL
Sbjct: 3496 NSSPTTAE--------VTSMPTSTAGEGSTPL 3519
Score = 46.6 bits (109), Expect = 8e-05
Identities = 156/729 (21%), Positives = 252/729 (34%), Gaps = 93/729 (12%)
Query: 18 TESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVSLNKVPPLVPKEAATLLV 77
TE++ ST+ +G + T TPS S P +L+ P T
Sbjct: 1608 TEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTE 1667
Query: 78 ARDNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLETGPGGASRFRERSLSVPT 137
+P G++ P + P LTS T R T P +S S + P
Sbjct: 1668 VSSSPTPAEGTS-MPTSTYTEGRTP--------LTSITVR--TTPVASSAISTLS-TTPV 1715
Query: 138 DSG---TTDVDYDEEQKANEACALPFASTSSEGSNSADNI-----ASLSAQQEAQHRRQR 189
D+ TT + +E ++P ST SEG+ +I LS++
Sbjct: 1716 DNSTPVTTSTEARSSPTTSEGTSMP-NSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPI 1774
Query: 190 SKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQGHHSSHP 249
S + + + S PT + L EG + L +L + E S+ P
Sbjct: 1775 DTSTPVTTSTEATSSPTTAEG-TSIPTSTLSEGMTPLTSTPVSHTLVANSE-ASTLSTTP 1832
Query: 250 DAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSES 309
P + ST S + S T + S STA + + T V S +
Sbjct: 1833 VDSNSPVV------TSTAVSSSPTPAEGTSIAT-STPSEGSTALTSIPVSTTTVASSETN 1885
Query: 310 LASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSM-SLTLGH 368
S + + +TP +V + ++ G +P G + P T ++ S +
Sbjct: 1886 TLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINT 1945
Query: 369 LPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLS-FDLPLTSSP------------NL 415
L + R + SS P T+ P S PLTS P L
Sbjct: 1946 LSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTL 2005
Query: 416 DLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMP---------MVTQSDLRSVR 466
+ + S + T S T G Q + P++ P +V S+ ++
Sbjct: 2006 STTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLS 2065
Query: 467 LRSV-SKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSV 525
V SK++ + E+ A + + P +E P+ P L P +
Sbjct: 2066 TTPVDSKTQVTNSTEASSSATAEGSSMTISAP--------SEGSPLLTSIP-LSTTPVAS 2116
Query: 526 PEEYAL-TSPTLAMPP--RSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLV 582
PE L T+P + P S+ + P+P + ++ + S++ D R+P S S+
Sbjct: 2117 PEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSM----QTSTYSDRRTPLTSMPVST-- 2170
Query: 583 FTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIP---PPVP 639
T ASS+ + S T V + + R P S + +G P PV
Sbjct: 2171 -TVVASSAISTLSTTPVDTSTPVTN-STEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVS 2228
Query: 640 KKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQA 699
P V T++ A P +P+ T E T P T + TS P +
Sbjct: 2229 TMPVV--------TSEASTLSATPVDTSTPVTTSTEATSSPTTAEG--------TSIPTS 2272
Query: 700 DSEREASPL 708
+PL
Sbjct: 2273 TLSEGTTPL 2281
Score = 44.7 bits (104), Expect = 3e-04
Identities = 104/427 (24%), Positives = 159/427 (37%), Gaps = 44/427 (10%)
Query: 285 SLSSSSTATGTTVIECTQVQGSSESLASPSTSR-ATTP-SQLSIEVEAREISSPGRP-PG 341
SL +S+T+ G+T++ T + S+ + SP S TTP V + E+SS P G
Sbjct: 1267 SLPTSTTSEGSTLL--TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEG 1324
Query: 342 LMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKS----------SLPP 391
P+S Y S+ TP ++ ++ TL SS++ + P S S P
Sbjct: 1325 TSMPTSTY-SEGRTPLTSIPVNTTL----VASSAISILSTTPVDNSTPVTTSTEACSSPT 1379
Query: 392 TSPMEKFPKSRLS-FDLPLTSSP--NLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTN 448
TS P S S PLTS P + S S T V T + T
Sbjct: 1380 TSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTT 1439
Query: 449 PNQPIMPMVTQSD----LRSVRLRS--VSKSEPEDDIESPEYAEEPRAEEVFTLPERKTK 502
+P T S+ L+S+ + + V+ SE +P + P V T +
Sbjct: 1440 AEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSP----VVTSTAVSSS 1495
Query: 503 PPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPK 562
P AE +A PS + + +++ T+A +S+ + T +
Sbjct: 1496 PTPAEGTSIAISTPS---EGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQAS 1552
Query: 563 PS-SFPDGRSPGEST-APSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERIS 620
S + DG S ST + S T S+ S + D +V E
Sbjct: 1553 SSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTE--- 1609
Query: 621 LQSQEEAEKKKGKIPPPVPKKPSVLYLPL-TSPTAQMEAYV--AEPRLPLSPIITLEEDT 677
S AE I P P + +P+ T+P A EA P SP+IT E +
Sbjct: 1610 ASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVS 1669
Query: 678 KCPATGD 684
P +
Sbjct: 1670 SSPTPAE 1676
Score = 43.5 bits (101), Expect = 7e-04
Identities = 92/406 (22%), Positives = 146/406 (35%), Gaps = 76/406 (18%)
Query: 284 QSLSSSSTATGTTVIECTQVQGSSESLASP----------STSRATTPSQLS--IEVEAR 331
++ SSS+TA GT++ T +GS+ + P +++ +TTP S +
Sbjct: 665 EATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTE 724
Query: 332 EISSPGRPPGLMSPSSGYSSQSETPTPTVSMSL-----------TLGHLP-------PPS 373
SSP G P+ S+ SE TP SM + TL P S
Sbjct: 725 ASSSPTTADGASMPT---STPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTS 781
Query: 374 SSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSIS---------I 424
+ P E +S+P ++P E P L +P++ +P ++S +
Sbjct: 782 TEASCSPTTTE-GTSMPISTPSEGSP---LLTSIPVSITPVTSPEASTLSTTPVDSNSPV 837
Query: 425 RSKTKVSRHHSETNFGVKLAQKT--NPNQPIMPMVTQSDLRSVRLRSVSKSEPEDD---- 478
+ T+VS + G + T P+ M + L + S + P D
Sbjct: 838 TTSTEVSSSPTPAE-GTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPV 896
Query: 479 IESPEYAEEPRAEEVFTLPERK--------TKPPVAEKPPVARRPPSLVHKP-----PSV 525
S E P E ++P T P + P V+ +L P P
Sbjct: 897 TNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVT 956
Query: 526 PEEYALTSPTLA----MPPRSSIQHARPLPQD--SYTVVRKPKPSSFPDGRSPGESTAPS 579
A +SPT A +P + + PL S+T+V + S+ +P +S P
Sbjct: 957 TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTL--STTPVDSNTP- 1013
Query: 580 SLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQE 625
L + ASS GT P E P R+ + S E
Sbjct: 1014 -LTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSE 1058
Score = 42.7 bits (99), Expect = 0.001
Identities = 118/504 (23%), Positives = 179/504 (35%), Gaps = 65/504 (12%)
Query: 110 LLTSGTSRLETGPGG----ASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFAST-- 163
+++S S L T P A+ E S S T GT+ ++ +P ++T
Sbjct: 1997 VVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLV 2056
Query: 164 -SSEGSNSA----DNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGL 218
SSEG+ + D+ ++ EA S A + SP S+ L P
Sbjct: 2057 VSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPL-STTPVA 2115
Query: 219 LPEGGSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWK 278
PE + S+ P P I ST+ S T+
Sbjct: 2116 SPEASTL--------------------STTPVDSNSPVIT------STEVSSSPIPTEGT 2149
Query: 279 SGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGR 338
S T + S T + + T V S+ S S + +TP S E + +S G
Sbjct: 2150 SMQT-STYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGT 2208
Query: 339 PPGLMSPSSGYSSQSETPTPTV----SMSLTLGHLPPPSSSVRVRPVVPERK-SSLPPTS 393
+PS G + + P T+ S + TL P +S+ PV + +S P T+
Sbjct: 2209 SMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST----PVTTSTEATSSPTTA 2264
Query: 394 PMEKFPKSRLS-FDLPLTSSP--NLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPN 450
P S LS PLTS P + ++ +S S T V + T +
Sbjct: 2265 EGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAE 2324
Query: 451 QPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEP--RAEEVFTLPERKTKPPVAEK 508
MP T S+ + R + E+ + P + V T + + P A+
Sbjct: 2325 GTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADD 2384
Query: 509 PPVARRPPSLVHKPPSVPEEYALTS-PTLAMPPRSSIQHAR-PLPQDSYTVVRKPKPSSF 566
+ P+ + S P LTS P MP SS P D+ T V +S
Sbjct: 2385 TSM----PTSTYSEGSTP----LTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASS 2436
Query: 567 PDGRSPGES--TAPSSLVFTPFAS 588
+ G S T+P S TP AS
Sbjct: 2437 SPTTAEGTSIPTSPPSEGTTPLAS 2460
Score = 41.6 bits (96), Expect = 0.003
Identities = 104/506 (20%), Positives = 188/506 (37%), Gaps = 67/506 (13%)
Query: 141 TTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKK 200
TT E+ +P ST+SEGS L++ + + S++I+L
Sbjct: 189 TTSTQASSSPTTPESTTIP-KSTNSEGSTP------LTSMPASTMKVASSEAITLLTTPV 241
Query: 201 KPSPPTRSVSLVKDEP---------GLLPEGGSALPKDQRPKSLCLSLEHQGHH-SSHPD 250
+ S P + P P GGS P + P S+ L + + S+ P
Sbjct: 242 EISTPVTISAQASSSPTTAEGPSLSNSAPSGGST-PLTRMPLSVMLVVSSEASTLSTTPA 300
Query: 251 AQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESL 310
A P I ST+ S SS +TA GT++ T +GS+
Sbjct: 301 ATNIPVIT------STEAS-----------------SSPTTAEGTSIPTSTYTEGSTPLT 337
Query: 311 ASPSTSRATTPSQLS-IEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHL 369
++P+++ S++S + + + S+ L++ S+ SS T T ++ TL
Sbjct: 338 STPASTMPVATSEMSTLSITPVDTST------LVTTSTEPSSLPTTAEATSMLTSTLSEG 391
Query: 370 PPPSSSVRVRPV-VPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKT 428
P +++ V + V ++S T P++ K+ ++ +SSP + SI + T
Sbjct: 392 STPLTNMPVSTILVASSEASTTSTIPVDS--KTFVTTASEASSSPT---TAEDTSIATST 446
Query: 429 KVSRHHSETNFGVK---LAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYA 485
T+ V +A N P+ +++ + + S S P ++ S +
Sbjct: 447 PSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT--STEASSSPPTAEVNSMPTS 504
Query: 486 EEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQ 545
T T P + + P P + E + +S T P +SI
Sbjct: 505 TPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTT---PEGTSIP 561
Query: 546 HARP----LPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPP 601
+ P P + V + SS S + + + + + ASSS GT P
Sbjct: 562 TSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSM-P 620
Query: 602 QGSVEDEGPKVRVLPERISLQSQEEA 627
+ + G + + +L + EA
Sbjct: 621 TSTYSERGTTITSMSVSTTLVASSEA 646
Score = 41.6 bits (96), Expect = 0.003
Identities = 70/322 (21%), Positives = 118/322 (36%), Gaps = 46/322 (14%)
Query: 287 SSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPS 346
S +T +T + T V S S S + + TP S E + ++ G +PS
Sbjct: 979 SEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPS 1038
Query: 347 SGYSSQSETPTPTV----SMSLTLGHLPPPSSSVRVRPVVP-ERKSSLPPTSPMEKFPKS 401
G + + P T S + TL P +S+ PV + SS T+ P S
Sbjct: 1039 EGSTPLTRMPVSTTMVASSETSTLSTTPADTST----PVTTYSQASSSSTTADGTSMPTS 1094
Query: 402 RLS-FDLPLTSSP------------NLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTN 448
S PLTS P L + + SI T S T +
Sbjct: 1095 TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSP 1154
Query: 449 PNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEK 508
P++ P+ + ++ + S + + ++S +V T E + PP AE
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDS--------KTQVATSTEASSPPPTAE- 1205
Query: 509 PPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPD 568
+ P S P E ++P +MP ++H ++ T+ P +S P
Sbjct: 1206 ---------VTSMPTSTPGE--RSTPLTSMP----VRHTPVASSEASTLSTSPVDTSTPV 1250
Query: 569 GRSPGESTAPSSLVFTPFASSS 590
S S++P++ T +S+
Sbjct: 1251 TTSAETSSSPTTAEGTSLPTST 1272
Score = 40.8 bits (94), Expect = 0.004
Identities = 87/444 (19%), Positives = 164/444 (36%), Gaps = 65/444 (14%)
Query: 284 QSLSSSSTATGTTVIECTQVQGSSE----------SLASPSTSRATTP----SQLSIEVE 329
Q+ SS +TA GT++ T +GS+ ++S + + +TTP +Q++ E
Sbjct: 1550 QASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTE 1609
Query: 330 A-REISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSS 388
A ++ G + +PS G + P T ++ P +S++ PV + S
Sbjct: 1610 ASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVA------SPEASTLSTTPV--DSNSP 1661
Query: 389 LPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTN 448
+ ++ + P +P ++ SI++R+ S S + T
Sbjct: 1662 VITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLS--------TT 1713
Query: 449 PNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAE-EVFTLPERKTKPPVAE 507
P P+ T ++ RS S S P +P P V T P ++
Sbjct: 1714 PVDNSTPVTTSTEARSSPTTSEGTSMPN---STPSEGTTPLTSIPVSTTPVLSSEASTLS 1770
Query: 508 KPPVARRPP----SLVHKPPSVPEEYALTSPTLA--MPPRSS--IQHARPLPQDSYTVVR 559
P+ P + P+ E ++ + TL+ M P +S + H ++ T+
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLST 1830
Query: 560 KPKPSSFPDGRSPGESTAPSSLVFTPFASSSDA----------FFSGTQQPPQGSVEDEG 609
P S+ P S S++P+ T A+S+ + + T + +
Sbjct: 1831 TPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTT 1890
Query: 610 PKVRVLPERISLQSQEEAEKKKGKIPP---PVPKKPSVLYLPLTSPTA------QMEAYV 660
P V P Q G P P +P + +P+++ T + +
Sbjct: 1891 PAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTL 1950
Query: 661 AEPRLPLSPIITLEEDTKCPATGD 684
A+ R +P+ T + + P T D
Sbjct: 1951 ADTR---TPVTTYSQASSSPTTAD 1971
Score = 40.4 bits (93), Expect = 0.006
Identities = 99/437 (22%), Positives = 155/437 (35%), Gaps = 50/437 (11%)
Query: 290 STATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGY 349
ST ++ T + S S S + +TP S E + ++ G + +PS G
Sbjct: 2691 STPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDG- 2749
Query: 350 SSQSETPTPTVSMSLTLGHLPPPSSSVRVRPV-------VPERKSSLPPTSPMEKFPKSR 402
TP ++ +S TL +S+V V SS P T+ + P S
Sbjct: 2750 ----STPLTSILVS-TLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTST 2804
Query: 403 LS-FDLPLTSSP--NLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQ 459
S PLTS P + ++ S T V T + T ++P+ T
Sbjct: 2805 PSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTA 2864
Query: 460 SDLRSVRLRSVSKSEPEDDIESPEYAEEP--RAEEVFTLPERKTKPPVAEKPPVARRPPS 517
S+ ++ + P E+ + P + V T E + P AE + PS
Sbjct: 2865 SEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPS 2924
Query: 518 LVHKPPS--------VPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFP-D 568
V P + V A T T + R+ + + T P S P +
Sbjct: 2925 EVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGE 2984
Query: 569 GRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAE 628
R+P S + S++ P ASS + S T P P S ++
Sbjct: 2985 RRTPLTSMSVSTM---PVASSEASTLSRT------------PADTSTPVTTSTEASSSPT 3029
Query: 629 KKKGK-IPPPVPKKPS--VLYLPL-TSPTAQMEAYV--AEPRLPLSPIITLEE--DTKCP 680
+G IP P + S + +P+ T+P A EA P SP++T E + P
Sbjct: 3030 TAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTP 3089
Query: 681 ATGDDLQSLGQRVTSTP 697
A G + STP
Sbjct: 3090 AEGTSMPISTYSEGSTP 3106
Score = 39.7 bits (91), Expect = 0.010
Identities = 96/439 (21%), Positives = 149/439 (33%), Gaps = 98/439 (22%)
Query: 284 QSLSSSSTATGTTV----------------IECTQVQGSSESLASPSTSRATTPSQLSIE 327
++ SS +TA GT++ + V S S S + + +TP S E
Sbjct: 2964 EASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTE 3023
Query: 328 VEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSL----TLGHLPPPSSSVRVRPVVP 383
+ ++ G + +PS G + + P T +++ TL P S+S PVV
Sbjct: 3024 ASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNS----PVVT 3079
Query: 384 ERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKL 443
+ S PT P S + S + L+G+ +S
Sbjct: 3080 STEVSSSPT------PAEGTSMPISTYSEGSTPLTGVPVS-------------------- 3113
Query: 444 AQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKP 503
T P VT S + ++ V S P S E P E ++P T
Sbjct: 3114 ---TTP-------VTSSAISTLSTTPVDTSTPV--TTSTEAHSSPTTSEGTSMP---TST 3158
Query: 504 PVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKP 563
P P+ P S + S + T + P +S + + ++ P
Sbjct: 3159 PSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSI-----P 3213
Query: 564 SSFP-DGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQ 622
+S P +G +P S S+ TP ASS + S T P P S +
Sbjct: 3214 TSTPSEGMTPLTSVPVSN---TPVASSEASILSTT------------PVDSNTPLTTSTE 3258
Query: 623 SQEEAEKKKG-KIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPA 681
+ +G +P P + S PLTS + LS T DT P
Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGST---PLTSMPVSTTTVASSETSTLS---TTPADTSTPV 3312
Query: 682 TGDDLQSLGQRVTSTPQAD 700
T + Q +S P AD
Sbjct: 3313 T-----TYSQASSSPPIAD 3326
Score = 38.1 bits (87), Expect = 0.028
Identities = 47/197 (23%), Positives = 80/197 (40%), Gaps = 27/197 (13%)
Query: 279 SGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGR 338
+ T +++ A T VI T++ S S +S +TS +TT +E ++P
Sbjct: 3947 TSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT----------KEFTTPAM 3996
Query: 339 PPGLMSPSSGYSSQSETPTPTV------SMSLTLGHLPPPSSSVRVRPVVPERKSSLPPT 392
S+ TP T + +L+ P S+SV RPV P +SS P T
Sbjct: 3997 TTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPST 4056
Query: 393 SPMEKFPKS---RLSFDLPLTSSPNLDLSGMSI-SIRSKTKVSRHHSE------TNFGVK 442
P + S P TS+ + ++ ++ ++ ++TK S + T
Sbjct: 4057 ITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTN 4116
Query: 443 LAQKTNP-NQPIMPMVT 458
K+NP + P +P T
Sbjct: 4117 TTIKSNPTSTPTVPRTT 4133
Score = 35.0 bits (79), Expect = 0.24
Identities = 111/447 (24%), Positives = 160/447 (35%), Gaps = 66/447 (14%)
Query: 289 SSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSG 348
SS + T + T++ + S STS +TT S E + SSP P G P S
Sbjct: 96 SSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTE----DTSSPTTPEGTDVPMST 151
Query: 349 YSSQSETPTPTVSMSLTLGHLPPPSSSV----RVRPVVPERKSSLPPTSP-MEKFPKSRL 403
S +S + T + L +S P+ ++S PT+P PKS
Sbjct: 152 PSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTN 211
Query: 404 S-FDLPLTSSP----------NLDLSGMSISIRSKTKVSRHHSE---TNFGVKLAQKTNP 449
S PLTS P + L + I + +S S T G L+ P
Sbjct: 212 SEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSA-P 270
Query: 450 NQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKP 509
+ P+ T+ L SV L V SE +P P V T E + P AE
Sbjct: 271 SGGSTPL-TRMPL-SVML--VVSSEASTLSTTPAATNIP----VITSTEASSSPTTAEGT 322
Query: 510 PVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPL-PQDSYTVV-RKPKPSSFP 567
+ P+ + S P ++P MP +S + P D+ T+V +PSS P
Sbjct: 323 SI----PTSTYTEGSTP---LTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLP 375
Query: 568 ----------DGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPE 617
S G + + V T +SS+A S T P S K V
Sbjct: 376 TTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEA--STTSTIPVDS------KTFVTTA 427
Query: 618 RISLQSQEEAEKKKGKIPPPVPKKPSVLYLPL-TSPTAQMEA--YVAEPRLPLSPIITLE 674
+ S AE P + +P+ T+P A EA P + + T
Sbjct: 428 SEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTST 487
Query: 675 EDTKCPATGDDLQSLGQRVTSTPQADS 701
E + P T + + TSTP S
Sbjct: 488 EASSSPPTAE----VNSMPTSTPSEGS 510
Score = 34.3 bits (77), Expect = 0.41
Identities = 102/459 (22%), Positives = 159/459 (34%), Gaps = 79/459 (17%)
Query: 285 SLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMS 344
S+ +S+ + GTT + V + + + ST T + + E SSP PP
Sbjct: 2268 SIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSP--PPTAEG 2325
Query: 345 PSSGYSSQSETPTPTVSMSL-----------TLGHLPPPSSSVRVRPVVP-ERKSSLPPT 392
S S+ SE TP M + TL P +S+ PV + S P T
Sbjct: 2326 TSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTST----PVTTYSQAGSSPTT 2381
Query: 393 SPMEKFPKSRLS-FDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQ 451
+ P S S PLTS P +S M + ++ S H T P
Sbjct: 2382 ADDTSMPTSTYSEGSTPLTSVP---VSTMPV---VSSEASTH------------STTPVD 2423
Query: 452 PIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPV 511
P+ T ++ S + S P P P A PV+ P V
Sbjct: 2424 TSTPVTTSTEASSSPTTAEGTSIP---TSPPSEGTTPLA-----------SMPVSTTPVV 2469
Query: 512 ARRPPSLVHKP-----PSVPEEYALTSPTLA---MPPRSSIQHARPLPQD---SYTVVRK 560
+ +L P P A +SPT A + P S+ L S T V
Sbjct: 2470 SSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVAS 2529
Query: 561 PKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERIS 620
P+ S+ +P +S +P +V + SSS GT P E P +
Sbjct: 2530 PEASTL--STTPVDSNSP--VVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKP 2585
Query: 621 LQSQEEAEKKKGKIPPPVPKKPSV-----------LYLPLTSPTAQMEAYVAEPRLPLSP 669
L S E + + +P S +P+++P +++ + + P
Sbjct: 2586 LASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTP-SEVSTSLTSILVSTMP 2644
Query: 670 IITLEEDTKCPATGDDLQSLGQRVTSTPQADSEREASPL 708
+ + E T T D ++L T T + + E S +
Sbjct: 2645 VASSEAST-LSTTPVDTRTLVTTSTGTSSSPTTAEGSSM 2682
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 53.1 bits (126), Expect = 9e-07
Identities = 99/442 (22%), Positives = 154/442 (34%), Gaps = 53/442 (11%)
Query: 306 SSESLASPSTSRATTPSQLSIEVEAREI---SSPGRPPGLMSPSSGYSSQSETPTPTVSM 362
SS +SP++SR+ TP + + ++ E+ SS P S G + TP +
Sbjct: 168 SSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADRESQGEKAADTTPRKKQNS 227
Query: 363 SLTLGHLPPPSSSVRVRPV--VPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGM 420
+ P SS R R V +P R+ P + S + DL L +L
Sbjct: 228 N---SQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQ 284
Query: 421 SISIRSKTKVSRHHSET--------NFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSK 472
++ +S S +ET F + A +P ++ T L S++
Sbjct: 285 ALEDKSDA-ASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPP 343
Query: 473 SEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVA---EKPPVARRPPSLVHKPPS----- 524
S P PE A E + PP+ PP PS KPP+
Sbjct: 344 SLP----PCPESAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGL 399
Query: 525 ------VPEEYALTSPTL----AMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGE 574
VP PTL A P+++ P P+ S+ + S P +P
Sbjct: 400 IPAPSMVPATDTKAPPTLQAETATKPQAT-SAPSPAPKQSFLFGTQNTSPSSP--AAPAA 456
Query: 575 STAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKI 634
S+AP +F P ++ PP SV P LP S +
Sbjct: 457 SSAPP--MFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMG 514
Query: 635 PPPVPKKPSVLYLPLTSP------TAQMEAYVAEPRLPLSPIITLEEDTKC---PATGDD 685
PP P+ + T+P TA + +A ++PI + T PA G
Sbjct: 515 PPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFG 574
Query: 686 LQSLGQRVTSTPQADSEREASP 707
+ S+ ST + + + P
Sbjct: 575 INSVSSSSVSTTTSTATAASQP 596
Score = 36.2 bits (82), Expect = 0.11
Identities = 113/561 (20%), Positives = 184/561 (32%), Gaps = 125/561 (22%)
Query: 76 LVARDNPAGCSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLETGPGG-ASRFRERSLS 134
LVA PA G +R + + + +K S +S + + G AS S +
Sbjct: 91 LVANGVPASFVPKPGSLKRGLNSQSSDDHLNK----RSRSSSMSSLTGAYASGIPSSSRN 146
Query: 135 VPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSIS 194
T S ++ + K N + PF+S +S S + + A ++E H S ++
Sbjct: 147 AITSSYSSTRGISQLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLA 206
Query: 195 LRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQGHHSSHPDAQ-- 252
+ + + ++ G S QR + + L +G + P
Sbjct: 207 ADRESQGEKAADTTPRKKQNSNSQSTPGSSG----QRKRKVQLLPSRRGEQLTLPPPPQL 262
Query: 253 GHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLAS 312
G+ D E + S W+ Q+L S A +V E + S +
Sbjct: 263 GYSITAEDLDLEK-KASLQWF---------NQALEDKSDAASNSVTETPPITQPSFTFTL 312
Query: 313 PSTSRATTPSQL--------------------------SIEVEAREISSPGRPPGLMSPS 346
P+ + A+ P+ L S E SP + P L+ P
Sbjct: 313 PAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLLPPL 372
Query: 347 SGYSSQSETPTPTVSM-----SLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKS 401
S P+ S + LG +P PS +VP + PPT E K
Sbjct: 373 GLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPS-------MVPATDTKAPPTLQAETATKP 425
Query: 402 RLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSD 461
+ TS+P+ FG Q T+P+ P P + +
Sbjct: 426 Q------ATSAPS----------------PAPKQSFLFG---TQNTSPSSPAAPAASSA- 459
Query: 462 LRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKP-PVAEKPPVARRPPSLVH 520
P + +FT P + K P P V PS
Sbjct: 460 -------------------------PPMFKPIFTAPPKSEKEGPTPPGPSVTATAPS--- 491
Query: 521 KPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSS 580
S+P + T+PT P SS+ +P + + P++ P +TAP
Sbjct: 492 -SSSLPTTTSTTAPTF-QPVFSSMGPPASVPLPAPFFKQTTTPATAP------TTTAP-- 541
Query: 581 LVFTPFASSSDAFFSGTQQPP 601
+FT AS++ A T P
Sbjct: 542 -LFTGLASATSAVAPITSASP 561
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/231 (23%), Positives = 97/231 (41%), Gaps = 35/231 (15%)
Query: 454 MPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLP-ERKTKPPVAEKPPVA 512
+P V + + ++ E + PE E+P EEV +P +K +PP + P V
Sbjct: 9261 VPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVP 9320
Query: 513 RRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTV-VRKPK---PSSFPD 568
++P KP VP++ P + P+ +P+P++ V V K K P+ P+
Sbjct: 9321 KKPVPEEKKPVPVPKKEPAAPPKVPEVPK------KPVPEEKIPVPVAKKKEAPPAKVPE 9374
Query: 569 GRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAE 628
+ G T + T + PP P V +P++ + ++
Sbjct: 9375 VQK-GVVTEEKITIVT----------QREESPP--------PAVPEIPKKKVPEERKPVP 9415
Query: 629 KKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAE----PRLPLSPIITLEE 675
+K+ ++PPP PK P++ P+ + VA+ PR +S +EE
Sbjct: 9416 RKEEEVPPP-PKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEE 9465
Score = 51.2 bits (121), Expect = 3e-06
Identities = 83/389 (21%), Positives = 138/389 (35%), Gaps = 75/389 (19%)
Query: 313 PSTSRATTPSQLSIEVEAREISSPGRPPGLMS---PSSGYSSQSETPTPTVSMSLTLGHL 369
P P ++ +E + R P PP + P + + P P
Sbjct: 10465 PPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKP----EA 10520
Query: 370 PPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTK 429
PPP + VVPE+K +PP PK ++P T P + + +
Sbjct: 10521 PPPKVPEAPKEVVPEKKVPVPP-------PKKP---EVPPTKVPEVPKAAV--------- 10561
Query: 430 VSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPE-DDIESPEYAEEP 488
E + K P +P + + ++ + +PE ++ PE +E
Sbjct: 10562 -----PEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKE- 10615
Query: 489 RAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPP--SVPEEYA--LTSPTLAMPPRSSI 544
+PE+K P +KP V PP+ V + P +VPE+ P PP
Sbjct: 10616 ------VVPEKKVPVPPPKKPEV---PPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVF 10666
Query: 545 QHAR--PLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQ 602
+ L + VV +P+P++ P P + P + A + + P
Sbjct: 10667 EEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPE--------KKAPAVVAKKPELPP 10718
Query: 603 GSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPP-----------PVPKKPSVLYLPLTS 651
V E PK V +++ L ++ E K+P VPKKP V
Sbjct: 10719 VKV-PEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEV------- 10770
Query: 652 PTAQMEAYVAEPRLPLSPIITLEEDTKCP 680
P A++ +P L P + + E + P
Sbjct: 10771 PPAKVPEVPKKPVLEEKPAVPVPERAESP 10799
Score = 47.8 bits (112), Expect = 4e-05
Identities = 83/356 (23%), Positives = 130/356 (36%), Gaps = 63/356 (17%)
Query: 371 PPSSSVRV-RPVVPERKSSLP-----PTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISI 424
PP+ V + VVPE+K ++P P + + + PK + + P P S
Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVY 10804
Query: 425 RSKTKVSRHHS---ETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIES 481
+++ E V +A++ P P P V + + + + V I+
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVP-PPAVPEEPKKIIPEKKVPV------IKK 10857
Query: 482 PEYA--EEPRAEEVFTLPERKTKPPVAEKPP-----------VARRPPSLVHKPPSVPEE 528
PE +EP E+V P+ K +PP P + P V + P VPE+
Sbjct: 10858 PEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEK 10917
Query: 529 YALTS---PTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTP 585
LT P R + +P P++ VV K P+ P V P
Sbjct: 10918 VELTPLKVPGGEKKVRKLLPERKPEPKEE--VVLKSVLRKRPEEEEPKVEPKKLEKVKKP 10975
Query: 586 FASSSDAFFSGTQQPPQGSVEDEGPKV----RVLPE---------RISLQSQEEAEKKKG 632
PP+ E E P V R +PE I L + E K +
Sbjct: 10976 AVPEPP--------PPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA 11027
Query: 633 KI----PPPVPKKPSVLYLPLTSPT----AQMEAYVAEPRLPLSPIITLEEDTKCP 680
++ PPPV +P+ + P+T P A+ +A E P PI + + T P
Sbjct: 11028 EVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSP 11083
Score = 43.5 bits (101), Expect = 7e-04
Identities = 110/514 (21%), Positives = 180/514 (35%), Gaps = 85/514 (16%)
Query: 149 EQKANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRS 208
E+K EA S E + +A E + + + KKP P ++
Sbjct: 10647 EKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKA 10706
Query: 209 VSLVKDEPGLLPEGGSALPKDQRP-KSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQ 267
++V +P L P +PK+ P K + L + + P A+ P +P PE
Sbjct: 10707 PAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKK---PEAPPAKV-PEVPKEVVPEKKV 10762
Query: 268 FSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIE 327
++ V E + E A P RA +P E
Sbjct: 10763 -----------------AVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYE 10805
Query: 328 VEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERK- 386
P ++P + + E P P +PPP+ + ++PE+K
Sbjct: 10806 -----------EPEEIAPEEEIAPEEEKPVPVAEEEEP--EVPPPAVPEEPKKIIPEKKV 10852
Query: 387 ------SSLPPTSP-----MEKFPKSRLSFDLPLTSSPNLDLSGMSISIRS--KTKVSRH 433
+ PP P +EK PK + P + P D+ +++ K KV
Sbjct: 10853 PVIKKPEAPPPKEPEPEKVIEK-PKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVP-E 10910
Query: 434 HSETNFGVKLAQKTNPN-----QPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEP 488
+ V+L P + ++P V L+SV + PE+ EEP
Sbjct: 10911 KPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEE--------EEP 10962
Query: 489 RAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHAR 548
+ E E+ KP V E PP +P V P E + PT I+ A
Sbjct: 10963 KVEP--KKLEKVKKPAVPEPPP--PKPVEEVEVPTVTKRERKIPEPTKV----PEIKPAI 11014
Query: 549 PLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDE 608
PLP KPKP + P + + P + + P + + + +
Sbjct: 11015 PLPAPE----PKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK 11070
Query: 609 GPKVRVLPERISLQSQEEAEKKK------GKIPP 636
GP ++ +P++ S EAE++K G+ PP
Sbjct: 11071 GP-IKGVPKK--TPSPIEAERRKLRPGSGGEKPP 11101
Score = 42.4 bits (98), Expect = 0.002
Identities = 79/348 (22%), Positives = 130/348 (37%), Gaps = 46/348 (13%)
Query: 368 HLPPPSSSVRVRPVVPE---RKSSLPPTSPMEK-FPKSRLSFDLPLTSSPNL-------- 415
++ P + V+PV E K PP ++K P+ ++ +P P
Sbjct: 9785 YITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPK 9844
Query: 416 ----DLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVS 471
+ +SI+ R K +V+ ++ V + K + +P+ + VR+ V
Sbjct: 9845 KVFEEKIRISITKREKEQVTEPAAK----VPMKPKRVVAEEKVPVPRKEVAPPVRVPEVP 9900
Query: 472 KS-EPEDDIESPEYA-----------EEPRAEEVFTLPERKTKPPVAEK-PPVARRPPSL 518
K EPE+ E EE EE + E + P + K P V R+P
Sbjct: 9901 KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960
Query: 519 VHKPPSVP---EEYALTSPTLAMPPRSSI-----QHARPLPQDSYTVVRKPKPSSFPDGR 570
KP VP E P + P + + +P P V +KP P
Sbjct: 9961 EKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP 10020
Query: 571 SPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAE-K 629
P + AP + V P P VE KV +P+++ + ++
Sbjct: 10021 VPKKVEAPPAKV--PEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVP 10078
Query: 630 KKGKIPPP-VPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEED 676
KK + PPP VPKK + +P+ P + E E +P ++ EE+
Sbjct: 10079 KKVEAPPPKVPKKREPVPVPVALPQEE-EVLFEEEIVPEEEVLPEEEE 10125
Score = 38.5 bits (88), Expect = 0.022
Identities = 55/247 (22%), Positives = 97/247 (39%), Gaps = 44/247 (17%)
Query: 370 PPPSSSVRVRPVVPERKSSLP-PTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKT 428
PPP + VPE K ++P P + P++ +S + + +S ++ +
Sbjct: 9423 PPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRV 9482
Query: 429 KVSRH---------HSETNFGVKLA--QKTNPNQPIMPMVTQSDLRSV--------RLRS 469
+V+RH +SE GV ++ ++ + VT+ ++ +L
Sbjct: 9483 EVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHI 9542
Query: 470 VSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPV------ARRPPSLVHK-- 521
+SK + E E E+ + +P + +PP A+ P ++ P+ V K
Sbjct: 9543 ISKRVEAEPAEVTERQEKKIVLKP-KIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKE 9601
Query: 522 ---PPSVPEEYALTSPTLAMPPRSSIQHARPLP-----------QDSYTVVRKPKPSSFP 567
PP VPEE P +PP+ I+ PLP Q+ +V K + P
Sbjct: 9602 KVPPPKVPEEPKKPVPEKKVPPK-VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPP 9660
Query: 568 DGRSPGE 574
R P E
Sbjct: 9661 KARVPEE 9667
Score = 37.7 bits (86), Expect = 0.037
Identities = 69/347 (19%), Positives = 123/347 (35%), Gaps = 36/347 (10%)
Query: 344 SPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRV-RPVVPERKSSLP-------PTSPM 395
+P + + P V + + PPP+ V + VPE K +P P + +
Sbjct: 9973 APPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKV 10032
Query: 396 EKFPKSRL-SFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKL------AQKTN 448
+ PK + +P+ + ++ + K + T K+ K
Sbjct: 10033 PEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKR 10092
Query: 449 PNQPIMPMVTQSDLRSVRLRSVSKSE--PEDDIESPEYAEEPRAEEVFTLPERKTKPPVA 506
P+ + Q + V + E PE++ PE EE EE LPE + PP
Sbjct: 10093 EPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPE-EEEVLPEEEEVLPEEEEIPPEE 10151
Query: 507 EK-PPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSS 565
E+ PP P + VPEE L +P + + + + V+ PK
Sbjct: 10152 EEVPPEEEYVPE---EEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI--PKKEE 10206
Query: 566 FPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEG-----PKVRVLPERIS 620
P + P T++P + + +E P + + E
Sbjct: 10207 APPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAP 10266
Query: 621 LQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPL 667
+ E +K + P PVPKK + +P A++ + E ++P+
Sbjct: 10267 PRVPEVIKKAVPEAPTPVPKK-------VEAPPAKVSKKIPEEKVPV 10306
Score = 36.2 bits (82), Expect = 0.11
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 470 VSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEY 529
+ K+ PE P+ E P A+ +PE K PV +K + P + P VPE+
Sbjct: 10273 IKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEV---PKKVPEKK 10329
Query: 530 ALTSPTLAMPP 540
L A+PP
Sbjct: 10330 VLVPKKEAVPP 10340
Score = 31.2 bits (69), Expect = 3.5
Identities = 39/169 (23%), Positives = 61/169 (36%), Gaps = 34/169 (20%)
Query: 477 DDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTL 536
++ E EY EE T PE+ P+ KP VPEE T P
Sbjct: 9769 EEYEEREYERYEEHEEYITEPEK----PIPVKP---------------VPEEPVPTKP-- 9807
Query: 537 AMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSG 596
PP ++ A P + + +K KP P + P E P +
Sbjct: 9808 KAPPAKVLKKAVPEEKVPVPIPKKLKP---PPPKVPEE----------PKKVFEEKIRIS 9854
Query: 597 TQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVL 645
+ + V + KV + P+R+ + + +K+ P VP+ P L
Sbjct: 9855 ITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL 9903
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 51.6 bits (122), Expect = 2e-06
Identities = 153/675 (22%), Positives = 219/675 (32%), Gaps = 85/675 (12%)
Query: 34 MTPSATSQSNQVNENGKNPSCGNSW-VSLNKVPPLVPKEAATLLVARD--NPAGCSGSAG 90
+TP+A G+ P + + +P P+ T NPA ++G
Sbjct: 39 VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASG 98
Query: 91 YPERLIQQRHMPERPSKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQ 150
ER ++ P SGT+R GP G R + +E
Sbjct: 99 RGERAPPAKNTSPGPVSSPGRASGTTR--PGPLGQKGLR--------------ISAEETV 142
Query: 151 KANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPS----PPT 206
+A P S S G+ + + A RR R+ + + PS PPT
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 207 ----RSVSLVKD----EPGLL----PEGGSALPKDQRPKSLCLSLEHQGHHS---SHPDA 251
+SVS + EP P G L QRP S LS S S P A
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGL---QRPASRSLSSSATPLSSPARSGPSA 259
Query: 252 QGHPAIPNHKD---PESTQFSHHWYLTDWK--SGDTYQSLSSSSTATGTTVIECTQVQGS 306
+G P P H P+ Q +T + + LSSS AT + +
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319
Query: 307 SESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTL 366
++ A+P + L+ + SP PP L + S TP S+T
Sbjct: 320 PDNAATPLPATLPPSPPLATPLPLAP-PSPSAPPSLQT----LPSPPATPPSQAPPSMTT 374
Query: 367 GHLPPPSSSVRVRPV-VPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDL--SGMSIS 423
+ P S + P+ VP +S +P S L L SP L S +++S
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL-GSPTLQATHSFLTMS 433
Query: 424 IR----SKTKVSRHHSETNFGVKL-AQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDD 478
R S T SR S L A + P P P+ T L S P
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP--PLQTSLSPAVSPLSSPLTIHPLQA 491
Query: 479 IESPEYAEEPRAEEVFTLPERKTK----PPVAEKPPVARRPPSLVHKPPSVPEEYALTSP 534
+ S +P +T+ PP + PP + P L + P P S
Sbjct: 492 LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
Query: 535 TLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFF 594
L P + P P + P P + P +P P AS
Sbjct: 552 PLTTPHLETPPCPAPCPLQA-----PPSPLTTPPPETPSSIATPPPQAPPALASPP---L 603
Query: 595 SGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTA 654
G PP + P+ P ++L + PP P P + L SP A
Sbjct: 604 QGLPSPPLSPLATPPPQA---PPXLALPPLQ--------APPSPPASPPLSPLATPSPQA 652
Query: 655 QMEAYVAEPRLPLSP 669
V + P SP
Sbjct: 653 PNALAVHLLQAPFSP 667
Score = 51.6 bits (122), Expect = 2e-06
Identities = 102/436 (23%), Positives = 148/436 (33%), Gaps = 90/436 (20%)
Query: 303 VQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSM 362
+Q +S L +P P+ ++ +++P PP +PSS + + P S
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP--PPE--TPSSIATPPPQAPPALASP 601
Query: 363 SLTLGHLPPPSSSVRVRPVVPERKSSLPPT----SPMEKFPKSRLSFDLPLTSSPNLDLS 418
L G PP S + P +LPP SP P S L+ P +PN
Sbjct: 602 PLQ-GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA--TPSPQAPNA--- 655
Query: 419 GMSISIRSKTKVSRHHSETNFG------VKLAQKTNPNQPIMPMVTQSDLRSVRLRS--- 469
++ H + F V+ + P+ P T L +
Sbjct: 656 -----------LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704
Query: 470 -VSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEE 528
V S P SP P+A P + P PP++ PS PP VP
Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS---PSAT-PPPRVPP- 759
Query: 529 YALTSPTLAMPPRSSIQH-----ARPLPQDSYTVVRKP------KPSSFPDGRSPGESTA 577
L +P L +PP A+P PQ + P P+SFP G++P +A
Sbjct: 760 -LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPSA 817
Query: 578 PSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPP 637
SL +P A+ PPQ P ++V PP
Sbjct: 818 --SLPMSPLATP----------PPQAPPVLAAPLLQV---------------------PP 844
Query: 638 VPKKPSVLYLPLTSPTAQMEAYVAEPRLPLS----PIITLEEDTKCPATGDDLQSLGQRV 693
P L P PT + V+ PRL L+ P +G DL
Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904
Query: 694 TSTPQADSEREASPLG 709
TSTP+ ++ P G
Sbjct: 905 TSTPEELRGYDSGPEG 920
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/212 (25%), Positives = 85/212 (40%), Gaps = 25/212 (11%)
Query: 306 SSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSM--S 363
+S + PS T P +P +P PS+ SS +TPTPT S
Sbjct: 822 ASTAAGMPSLQHTTPPGM-----------TPPQPAAPTQPSTPVSSSGQTPTPTPGSVPS 870
Query: 364 LTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSP---NLDLSGM 420
T P + V P+ ++ + P P P+S P+ + P L +
Sbjct: 871 ATQTQSTPTVQAAAQAQVTPQPQTPVQP--PSVATPQSSQQQPTPVHAQPPGTPLSQAAA 928
Query: 421 SISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRL-RSVSKSEPEDDI 479
SI R T S +ETN +Q+ P+ P++ M T++ SK EP ++
Sbjct: 929 SIDNRVPTPSSVASAETN-----SQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 983
Query: 480 ESPEYAEEPRAEEVFTLPERKTKP-PVAEKPP 510
+ + +E + E+K++P V EK P
Sbjct: 984 MEEDLQGASQVKEETDIAEQKSEPMEVDEKKP 1015
Score = 47.8 bits (112), Expect = 4e-05
Identities = 98/483 (20%), Positives = 169/483 (34%), Gaps = 68/483 (14%)
Query: 171 ADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQ 230
A+ I + + E + R + K L P+P + + + +P P G +LP ++
Sbjct: 617 AEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNR 676
Query: 231 RPKSLCLSLEHQGHHSSHPDAQGHPAIPNHK-DPESTQFSHHWYLTDWKSGDTYQSLSSS 289
S QG +S +P + G+ +P P + +H ++S
Sbjct: 677 MQVS-------QGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSV-----------QMNSM 718
Query: 290 STATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGY 349
+ G + Q + A + A P+Q + + SS G M
Sbjct: 719 GSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQ 778
Query: 350 SSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPL 409
+ S+ P ++ L L P +S + P P +S L PT P
Sbjct: 779 TGVSQGQVPGAALPNPLNMLGPQASQL---PCPPVTQSPLHPTPP--------------- 820
Query: 410 TSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRS 469
P +GM S H+ T G+ Q P QP P+ + + S
Sbjct: 821 ---PASTAAGMP---------SLQHT-TPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGS 867
Query: 470 VSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVH-KPPSVPEE 528
V + + + A + +V P+ +PP P +++ P+ VH +PP P
Sbjct: 868 VPSATQTQSTPTVQAAAQ---AQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLS 924
Query: 529 YALTSPTLAMPPRSSIQHARPLPQ----DSYTVVRKPKPSSFPDGRSPGESTA-PSSLVF 583
A S +P SS+ A Q D + K + + PGES P S +
Sbjct: 925 QAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMM 984
Query: 584 TPFASSSDAFFSGTQQPPQGS----VEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVP 639
+ T Q S V+++ P+V+V ++ +EE+ P
Sbjct: 985 EEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKV-----EVKEEEESSSNGTASQSTSP 1039
Query: 640 KKP 642
+P
Sbjct: 1040 SQP 1042
Score = 42.0 bits (97), Expect = 0.002
Identities = 65/274 (23%), Positives = 110/274 (40%), Gaps = 57/274 (20%)
Query: 451 QPIMPMVTQSDLRSVRLRSVS-KSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKP 509
Q I + Q+ L R+ +++ ++ P+ + SP A + + P+ P +
Sbjct: 1815 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS 1874
Query: 510 PVARRP---PSLVH-KPPSV-----PEEYALTSPTLAMPPRSSIQHARPLPQDSYT---V 557
PV+ P PS+ +PP+ P P A PP ++++ AR + +++ +
Sbjct: 1875 PVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHL 1934
Query: 558 VRKPKPSSFPDGRS----PGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVR 613
R +S P GR+ PG AP SL +P Q S GP
Sbjct: 1935 YRVNINNSMPPGRTGMGTPGSQMAPVSL--------------NVPRPNQVS----GP--- 1973
Query: 614 VLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLP------- 666
V+P Q Q+ P+P++ + LP + Q +A VA PR+P
Sbjct: 1974 VMPSMPPGQWQQA----------PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRS 2023
Query: 667 LSP--IITLEEDTKCPATGDDLQSLGQRVTSTPQ 698
+SP + L K P++ Q + + S PQ
Sbjct: 2024 ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQ 2057
Score = 35.0 bits (79), Expect = 0.24
Identities = 67/345 (19%), Positives = 129/345 (37%), Gaps = 24/345 (6%)
Query: 366 LGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIR 425
LG+ P + PV+P+ + PP P+ P +R+ + S + L ++ +
Sbjct: 641 LGNQPALPAPGAQPPVIPQAQPVRPPNGPL-SLPVNRMQVSQGMNSFNPMSLG--NVQLP 697
Query: 426 SKTKVSRHHSETNFGVKL-AQKTNPNQPIMP--MVTQSDLRSVRLRSVSKSEPEDDIESP 482
R S N V++ + + P I P M ++ ++ P P
Sbjct: 698 QAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLP 757
Query: 483 EYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSV--PEEYALTSPTLAMPP 540
+ + P + ++ +PP + P + + P ++ P+ L P + P
Sbjct: 758 Q-NQFPSSSGAMSV--GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP 814
Query: 541 RSSIQHARPLPQDSYTVVRKPK-PSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQ 599
P P + T P + P G +P + AP+ TP +SS
Sbjct: 815 ------LHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQ-PSTPVSSSGQTPTPTPGS 867
Query: 600 PPQGSVEDEGPKVRVLPE-RISLQSQEEAEKKKGKIPPPVPKKPSVLYL-PLTSPTAQME 657
P + P V+ + +++ Q Q + P ++P+ ++ P +P +Q
Sbjct: 868 VPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAA 927
Query: 658 AYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQADSE 702
A + + R+P +P +T G D+ L + T T D+E
Sbjct: 928 ASI-DNRVP-TPSSVASAETNSQQPGPDVPVLEMK-TETQAEDTE 969
Score = 31.6 bits (70), Expect = 2.7
Identities = 65/308 (21%), Positives = 113/308 (36%), Gaps = 24/308 (7%)
Query: 107 KIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSE 166
++GLL SG P AS+ ++ S + SG++ A+ +
Sbjct: 50 ELGLLNSGN----LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQG 105
Query: 167 GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEG--GS 224
NSA N+ASLSA ++ + S + SL K S PT + S + G S
Sbjct: 106 QPNSA-NMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATS 164
Query: 225 ALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWK---SGD 281
+ Q +C++ H ++ ++ N Q + + +G
Sbjct: 165 SPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGM 224
Query: 282 TYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSP----- 336
Y + + ++ TQV A +T++A +++ I P
Sbjct: 225 PYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAG 284
Query: 337 GRP-------PGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSL 389
G+P P L S S +S PT + S+T ++P S +VP + +
Sbjct: 285 GQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVT--NVPNMSQMQTSVGIVPTQAIAT 342
Query: 390 PPTSPMEK 397
PT+ EK
Sbjct: 343 GPTADPEK 350
Score = 30.8 bits (68), Expect = 4.5
Identities = 54/286 (18%), Positives = 108/286 (37%), Gaps = 23/286 (8%)
Query: 308 ESLASPSTSRATTPSQL-SIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTL 366
+SL SP+++ TP+Q S + + P P MSP+ S P TVS
Sbjct: 1842 QSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1901
Query: 367 GHLPPPSSSVRVRPVVPERKSSLPPTSPMEK-FPKSRLSFDLPL----TSSPNLDLSGMS 421
+P P + P E + + ++ + ++ +P +P ++ +S
Sbjct: 1902 SQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVS 1961
Query: 422 ISIRSKTKVSRHHSETNFGVKLAQKTNPNQ--------PIMPMVTQSDLRSVRL------ 467
+++ +VS + + Q P Q P++ M Q+ + R+
Sbjct: 1962 LNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPP 2021
Query: 468 RSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPE 527
RS+S S +D + + + P+ ++ L K+ P + R + ++P P+
Sbjct: 2022 RSISPSALQDLLRTLKSPSSPQQQQQ-VLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQ 2080
Query: 528 EYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPG 573
+ P M P+ + L + P+P P ++ G
Sbjct: 2081 PGLQSQP--GMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMG 2124
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/212 (25%), Positives = 85/212 (40%), Gaps = 25/212 (11%)
Query: 306 SSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSM--S 363
+S + PS T P +P +P PS+ SS +TPTPT S
Sbjct: 860 ASTAAGMPSLQHTTPPGM-----------TPPQPAAPTQPSTPVSSSGQTPTPTPGSVPS 908
Query: 364 LTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSP---NLDLSGM 420
T P + V P+ ++ + P P P+S P+ + P L +
Sbjct: 909 ATQTQSTPTVQAAAQAQVTPQPQTPVQP--PSVATPQSSQQQPTPVHAQPPGTPLSQAAA 966
Query: 421 SISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRL-RSVSKSEPEDDI 479
SI R T S +ETN +Q+ P+ P++ M T++ SK EP ++
Sbjct: 967 SIDNRVPTPSSVASAETN-----SQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 1021
Query: 480 ESPEYAEEPRAEEVFTLPERKTKP-PVAEKPP 510
+ + +E + E+K++P V EK P
Sbjct: 1022 MEEDLQGASQVKEETDIAEQKSEPMEVDEKKP 1053
Score = 47.8 bits (112), Expect = 4e-05
Identities = 98/483 (20%), Positives = 169/483 (34%), Gaps = 68/483 (14%)
Query: 171 ADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQ 230
A+ I + + E + R + K L P+P + + + +P P G +LP ++
Sbjct: 655 AEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNR 714
Query: 231 RPKSLCLSLEHQGHHSSHPDAQGHPAIPNHK-DPESTQFSHHWYLTDWKSGDTYQSLSSS 289
S QG +S +P + G+ +P P + +H ++S
Sbjct: 715 MQVS-------QGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSV-----------QMNSM 756
Query: 290 STATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGY 349
+ G + Q + A + A P+Q + + SS G M
Sbjct: 757 GSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQ 816
Query: 350 SSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPL 409
+ S+ P ++ L L P +S + P P +S L PT P
Sbjct: 817 TGVSQGQVPGAALPNPLNMLGPQASQL---PCPPVTQSPLHPTPP--------------- 858
Query: 410 TSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRS 469
P +GM S H+ T G+ Q P QP P+ + + S
Sbjct: 859 ---PASTAAGMP---------SLQHT-TPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGS 905
Query: 470 VSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVH-KPPSVPEE 528
V + + + A + +V P+ +PP P +++ P+ VH +PP P
Sbjct: 906 VPSATQTQSTPTVQAAAQ---AQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLS 962
Query: 529 YALTSPTLAMPPRSSIQHARPLPQ----DSYTVVRKPKPSSFPDGRSPGESTA-PSSLVF 583
A S +P SS+ A Q D + K + + PGES P S +
Sbjct: 963 QAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMM 1022
Query: 584 TPFASSSDAFFSGTQQPPQGS----VEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVP 639
+ T Q S V+++ P+V+V ++ +EE+ P
Sbjct: 1023 EEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKV-----EVKEEEESSSNGTASQSTSP 1077
Query: 640 KKP 642
+P
Sbjct: 1078 SQP 1080
Score = 42.0 bits (97), Expect = 0.002
Identities = 65/274 (23%), Positives = 110/274 (40%), Gaps = 57/274 (20%)
Query: 451 QPIMPMVTQSDLRSVRLRSVS-KSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKP 509
Q I + Q+ L R+ +++ ++ P+ + SP A + + P+ P +
Sbjct: 1853 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS 1912
Query: 510 PVARRP---PSLVH-KPPSV-----PEEYALTSPTLAMPPRSSIQHARPLPQDSYT---V 557
PV+ P PS+ +PP+ P P A PP ++++ AR + +++ +
Sbjct: 1913 PVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHL 1972
Query: 558 VRKPKPSSFPDGRS----PGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVR 613
R +S P GR+ PG AP SL +P Q S GP
Sbjct: 1973 YRVNINNSMPPGRTGMGTPGSQMAPVSL--------------NVPRPNQVS----GP--- 2011
Query: 614 VLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLP------- 666
V+P Q Q+ P+P++ + LP + Q +A VA PR+P
Sbjct: 2012 VMPSMPPGQWQQA----------PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRS 2061
Query: 667 LSP--IITLEEDTKCPATGDDLQSLGQRVTSTPQ 698
+SP + L K P++ Q + + S PQ
Sbjct: 2062 ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQ 2095
Score = 35.0 bits (79), Expect = 0.24
Identities = 67/345 (19%), Positives = 129/345 (37%), Gaps = 24/345 (6%)
Query: 366 LGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIR 425
LG+ P + PV+P+ + PP P+ P +R+ + S + L ++ +
Sbjct: 679 LGNQPALPAPGAQPPVIPQAQPVRPPNGPL-SLPVNRMQVSQGMNSFNPMSLG--NVQLP 735
Query: 426 SKTKVSRHHSETNFGVKL-AQKTNPNQPIMP--MVTQSDLRSVRLRSVSKSEPEDDIESP 482
R S N V++ + + P I P M ++ ++ P P
Sbjct: 736 QAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLP 795
Query: 483 EYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSV--PEEYALTSPTLAMPP 540
+ + P + ++ +PP + P + + P ++ P+ L P + P
Sbjct: 796 Q-NQFPSSSGAMSV--GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP 852
Query: 541 RSSIQHARPLPQDSYTVVRKPK-PSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQ 599
P P + T P + P G +P + AP+ TP +SS
Sbjct: 853 ------LHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQ-PSTPVSSSGQTPTPTPGS 905
Query: 600 PPQGSVEDEGPKVRVLPE-RISLQSQEEAEKKKGKIPPPVPKKPSVLYL-PLTSPTAQME 657
P + P V+ + +++ Q Q + P ++P+ ++ P +P +Q
Sbjct: 906 VPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAA 965
Query: 658 AYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQADSE 702
A + + R+P +P +T G D+ L + T T D+E
Sbjct: 966 ASI-DNRVP-TPSSVASAETNSQQPGPDVPVLEMK-TETQAEDTE 1007
Score = 31.6 bits (70), Expect = 2.7
Identities = 65/308 (21%), Positives = 113/308 (36%), Gaps = 24/308 (7%)
Query: 107 KIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSE 166
++GLL SG P AS+ ++ S + SG++ A+ +
Sbjct: 50 ELGLLNSGN----LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQG 105
Query: 167 GSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEG--GS 224
NSA N+ASLSA ++ + S + SL K S PT + S + G S
Sbjct: 106 QPNSA-NMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATS 164
Query: 225 ALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWK---SGD 281
+ Q +C++ H ++ ++ N Q + + +G
Sbjct: 165 SPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGM 224
Query: 282 TYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSP----- 336
Y + + ++ TQV A +T++A +++ I P
Sbjct: 225 PYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAG 284
Query: 337 GRP-------PGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSL 389
G+P P L S S +S PT + S+T ++P S +VP + +
Sbjct: 285 GQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVT--NVPNMSQMQTSVGIVPTQAIAT 342
Query: 390 PPTSPMEK 397
PT+ EK
Sbjct: 343 GPTADPEK 350
Score = 30.8 bits (68), Expect = 4.5
Identities = 54/286 (18%), Positives = 108/286 (37%), Gaps = 23/286 (8%)
Query: 308 ESLASPSTSRATTPSQL-SIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTL 366
+SL SP+++ TP+Q S + + P P MSP+ S P TVS
Sbjct: 1880 QSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1939
Query: 367 GHLPPPSSSVRVRPVVPERKSSLPPTSPMEK-FPKSRLSFDLPL----TSSPNLDLSGMS 421
+P P + P E + + ++ + ++ +P +P ++ +S
Sbjct: 1940 SQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVS 1999
Query: 422 ISIRSKTKVSRHHSETNFGVKLAQKTNPNQ--------PIMPMVTQSDLRSVRL------ 467
+++ +VS + + Q P Q P++ M Q+ + R+
Sbjct: 2000 LNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPP 2059
Query: 468 RSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPE 527
RS+S S +D + + + P+ ++ L K+ P + R + ++P P+
Sbjct: 2060 RSISPSALQDLLRTLKSPSSPQQQQQ-VLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQ 2118
Query: 528 EYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPG 573
+ P M P+ + L + P+P P ++ G
Sbjct: 2119 PGLQSQP--GMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMG 2162
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 51.6 bits (122), Expect = 2e-06
Identities = 104/406 (25%), Positives = 142/406 (34%), Gaps = 69/406 (16%)
Query: 322 SQLSIEVEAREIS-----SPGRPPGLMSPSSGYSSQSE-TPTPTVSMSLTLGHLPPPSSS 375
S LS EA +S SP PP SP S S +P P VS L PP
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS------RLSPPPEE 668
Query: 376 VRVRPVVPERKSSLPP-----TSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKV 430
+ P E +S PP + P E P S D P +SP + S MS+ + +
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP--ASPPPEDSLMSLPLEESPLL 726
Query: 431 SRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKS-EPEDDIESPEYAE--- 486
P +P + ++ S R S PE+ SP+ E
Sbjct: 727 PL----------------PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL 770
Query: 487 EPRAEE--VFTLPERKTKPPVAEKPPVARRPPSLVHKPPS-------VPEEYALT--SPT 535
P+ EE + +PE P AE P ++ +P L P + VPEE L+
Sbjct: 771 SPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830
Query: 536 LAMPPRSSIQHARPLPQDSYTVVRKPKPSSFP----DGRSPGESTAPSSLVFTPFASSSD 591
+ P+S P P++S+ KP P PG+ AP L F +
Sbjct: 831 SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPL--FPPPGE 888
Query: 592 AFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLTS 651
S P S E P + LPE + L E +PP PL
Sbjct: 889 PSLSPLLGEPALSEPGE-PPLSPLPEELPLSPSGEPSLSPQLMPPD----------PLPP 937
Query: 652 PTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTP 697
P + + A P LSP+ LE D L + TP
Sbjct: 938 PLSPIITAAAPP--ALSPLGELEYPFGAKGDSDPESPLAAPILETP 981
Score = 44.3 bits (103), Expect = 4e-04
Identities = 95/394 (24%), Positives = 137/394 (34%), Gaps = 35/394 (8%)
Query: 336 PGRPPGLMSPSSGYSSQSETPTPTVSMSLT-----LGHLPPPSSSVRVRPVVPERKSSLP 390
P PP SP S +S T P + L+ L P P + RP+ S P
Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPP 498
Query: 391 PTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKT--- 447
SP+ P+S S PL SP S +T +S + +
Sbjct: 499 EESPLSPPPES--SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP 556
Query: 448 NPNQ-PIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVA 506
P + P P S L S PE+ SP P A +F E P
Sbjct: 557 PPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP----PEASRLFPPFEESPLSPPP 612
Query: 507 EKPPVARRPPSLVHKPPSVPEEYALTSPTLAMP--PRSSIQHARPLPQDSYTVVRKPKPS 564
E+ P++ P + PP PE+ ++ P P P + PLP VV + P
Sbjct: 613 EESPLSPPPEASRLSPP--PEDSPMSPPPEESPMSPPPEVSRLSPLP-----VVSRLSPP 665
Query: 565 SFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRV----LPERIS 620
SP +P+S S S T PP+ S P+ + L E
Sbjct: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
Query: 621 LQSQEEAE---KKKGKIPPPVPKKPSVL---YLPLTSPTAQMEAYVAEPRLPLSPIITLE 674
L EE + + +G P P++P + P SP A+ +P P + E
Sbjct: 726 LPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
Query: 675 EDTKCPATGDDLQSLGQRVTSTPQADSEREASPL 708
A G L + + +PQ + E SP+
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTE-EPHLSPV 818
Score = 34.3 bits (77), Expect = 0.41
Identities = 37/109 (33%), Positives = 46/109 (42%), Gaps = 18/109 (16%)
Query: 480 ESPEYAEEPRAEEVFT-----LPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSP 534
ESP A EP + +T L R+ P E+P + P L P S P E + P
Sbjct: 4882 ESP--APEPPTQHSYTYNVSNLDVRQLSAPPPEEP--SPPPSPLAPSPASPPTEPLVELP 4937
Query: 535 T--LAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSL 581
T LA PP S PLP S +PKP + P GE + P L
Sbjct: 4938 TEPLAEPPVPS-----PLPLASSPESARPKPRARPP--EEGEDSRPPRL 4979
Score = 32.3 bits (72), Expect = 1.6
Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 30/104 (28%)
Query: 571 SPGESTAPSSLVFTP-----FASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQE 625
SP + AP+ + +P ++S+D F +PP GSV GP P + L
Sbjct: 2115 SPPPAAAPTIFIGSPTTPAGLSTSADGFL----KPPAGSVP--GPDS---PGELFL---- 2161
Query: 626 EAEKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSP 669
K+PP VP + +P P AY EPR P +P
Sbjct: 2162 -------KLPPQVPAQ-----VPSQDPFGLAPAYPLEPRFPTAP 2193
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 51.2 bits (121), Expect = 3e-06
Identities = 91/437 (20%), Positives = 156/437 (35%), Gaps = 68/437 (15%)
Query: 302 QVQGSSESLASPSTSRATTP---SQLSIEVEAR-----------------EISSPGR--- 338
+ +G E SP A +P ++ ++ EA+ E+ SP +
Sbjct: 493 EAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS 552
Query: 339 --------PPGLMSPSSGYS-SQSETPTPTVSMSLTLGHLPPP----SSSVRVRPVVPER 385
PP SP + S +E +P + S P S PV E
Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 386 KSSLPPTSPMEKFPKSRLSFDLP-LTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLA 444
KS SP+++ KS P SP + + +S K E A
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 445 QKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPP 504
+ +P + P+ ++ + +KS +++ +SPE A+ P EE + PE K K P
Sbjct: 673 EAKSPEKAKSPVKAEA-----KSPEKAKSPVKEEAKSPEKAKSPVKEEAKS-PE-KAKSP 725
Query: 505 VAEKPPVARRPPSLVHKPPSVPE-----EYALTSPTLAMPPRSSIQHARPLPQDSY---- 555
V E+ + S V + PE E A T + ++ + P D +
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 556 -----TVVRKPKPSSFP---DGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVED 607
V+ P+ + P D ++P + V +P ++PP+ + E+
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 608 EGPKVRVLPERISLQSQEEAEKKKGKIP------PPVPKKPSVLYLPLTSPTAQMEAYVA 661
+ P E+ +EEA KK+ P P +KP + A+ + V
Sbjct: 846 KAPATPKTEEKKD-SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVP 904
Query: 662 EPRLPLSPIITLEEDTK 678
P + ++ED K
Sbjct: 905 TPEKEAPAKVEVKEDAK 921
Score = 43.9 bits (102), Expect = 5e-04
Identities = 69/300 (23%), Positives = 120/300 (40%), Gaps = 34/300 (11%)
Query: 403 LSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDL 462
+ F LP P + I ++S+ K+ V + ++T Q + VT+ +
Sbjct: 418 IPFSLP-EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQ-VTEEVTEEEE 475
Query: 463 RSVRLRSVSKSEPEDDIESPEYAEE---PRAEEVFTLPERKTKPPV---AEKPPVARRPP 516
+ + + E ++ E+ EE P AEE + PE++ K PV A+ P A+ P
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAAS-PEKEAKSPVKEEAKSPAEAKSPE 534
Query: 517 SLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQD-------SYTVVRKPKPSSFP-- 567
K P+ + SP A P + P + S V+ P+ + P
Sbjct: 535 KEEAKSPA-----EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAK 589
Query: 568 -DGRSPGESTAP---SSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQS 623
+ +SP E+ +P S V S ++A S ++ + E + P+ P + +S
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEA-KSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 624 QEEA---EKKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCP 680
E+A EK++ K P K S + SP AE + P ++E+ K P
Sbjct: 649 PEKAKSPEKEEAKSP---EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Score = 36.6 bits (83), Expect = 0.082
Identities = 54/267 (20%), Positives = 99/267 (37%), Gaps = 20/267 (7%)
Query: 445 QKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPED--DIESPEYAEEPRAEEVFTLPERKTK 502
+ +P + V + +S K E + +++SPE A+ P EE + PE K+
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP 567
Query: 503 PPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPP---RSSIQHARPLPQDSYTVVR 559
K P + P P EE SP A P +S ++ P ++ + V
Sbjct: 568 EKEEAKSPAEVKSPEKAKSP--AKEE--AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPV- 622
Query: 560 KPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQQPPQG----SVEDEGPKVRVL 615
K + S + +SP ++ +P+ + + P + E + P+
Sbjct: 623 KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKS 682
Query: 616 PERISLQSQEEAE---KKKGKIPPPVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIIT 672
P + +S E+A+ K++ K P K S + SP E + P
Sbjct: 683 PVKAEAKSPEKAKSPVKEEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSP 739
Query: 673 LEEDTKCPATGDDLQSLGQRVTSTPQA 699
++E+ K P + +P+A
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEA 766
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 51.2 bits (121), Expect = 3e-06
Identities = 92/382 (24%), Positives = 141/382 (36%), Gaps = 78/382 (20%)
Query: 336 PGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPP---SSSVRVRPV--VPERKSSLP 390
P + PG PS ++ P+ + P P S+ +PV K P
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Query: 391 PT-SPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNP 449
PT SP K P S+ LP T P + + + + + K + +E V NP
Sbjct: 570 PTVSPSAKQPPSQ---GLPKTICPLCNTTELLLHVPEKANFNTC-TECQTTVCSLCGFNP 625
Query: 450 NQPI-----------------------MPMVTQSDLRSVRLRS---VSKSEPEDDIESPE 483
N + +P Q L++ + + VSKS P+ SP+
Sbjct: 626 NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPK 685
Query: 484 YAEEPRAEEVFTLPERKTKPPVAEKPPV-------ARRPPSL--VHKP-----PSVPEEY 529
P+ +++ PE K PP+ ++P + A++PP + KP PSVP E
Sbjct: 686 KDAAPK-QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Query: 530 -------------ALTSPTLAMPPRSSIQHARPLPQDSY--TVVRKPKPSSFPDGRSPGE 574
+ PT + SS +P K P D P +
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ 804
Query: 575 STAPSSLVFTPFASSS---DAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKK 631
S P+ +PF S + A S P S E +G K +V P +Q +EE +K +
Sbjct: 805 SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK-QVDP----VQKKEEPKKAQ 859
Query: 632 GKIPPPVPKKPSVLYLPLTSPT 653
K+ P KP +P SPT
Sbjct: 860 TKMSP----KPDAKPMPKGSPT 877
Score = 43.9 bits (102), Expect = 5e-04
Identities = 103/430 (23%), Positives = 149/430 (34%), Gaps = 104/430 (24%)
Query: 305 GSSESLASPSTSRATTPSQLSIEVEAREISS-----PGRPPGLMSPSSGYSSQSETPTPT 359
GS A P+ A SQLS E E R+I++ G P G + P++ +E+P+
Sbjct: 30 GSPSHTAIPAGMEADL-SQLS-EEERRQIAAVMSRAQGLPKGSVPPAA-----AESPSMH 82
Query: 360 VSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSG 419
L H P S RP P R + P S R LP S + L
Sbjct: 83 RKQELDSSHPPKQSG----RPPDPGRPAQ-PGLSKSRTTDTFRSEQKLPGRSPSTISLK- 136
Query: 420 MSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMP-MVTQSDLRSVRLRSVSKSEPEDD 478
+S+T + H + +MP +++ + S V+K P D
Sbjct: 137 ---ESKSRTDLKEEHKSS---------------MMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 479 IESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHK--------------PPS 524
I E ++E ++ + + + KP KPP+ ++PP + K P S
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 525 V----PEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSP----GEST 576
+ PE+ P P IQ PQ + + + +S P + GES
Sbjct: 239 ISSQQPEKIKSQPPGTGKP----IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 577 APSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPP 636
PS P S QQP G + P E+++
Sbjct: 295 KPS----LPSPSKPP-----IQQPTPGKPPAQQP------------GHEKSQ-------- 325
Query: 637 PVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTST 696
P P KP LT P AQ V P P TK PA Q LG
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQP-------PGTTKPPA-----QPLGPAKPPA 373
Query: 697 PQADSEREAS 706
Q SE+ +S
Sbjct: 374 QQTGSEKPSS 383
Score = 38.9 bits (89), Expect = 0.017
Identities = 73/312 (23%), Positives = 111/312 (35%), Gaps = 74/312 (23%)
Query: 307 SESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTV-SMSLT 365
S +A P + +T S E +E + P G SPS SS P P S SL
Sbjct: 2345 SSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSG--SPS--VSSLPAKPRPFFRSSSLD 2400
Query: 366 LGHLPPPSSSVRVRPVVPERKSSLPPTSPMEK-----FPKSRLSFDLPLTSS-PNLDLSG 419
+ PPP P P PP P PK +L+ P+T++ P D
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD--- 2457
Query: 420 MSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDI 479
+++ T V R + ++ P P P S L
Sbjct: 2458 -AVTTLETTAVLRSNGLPV--TRICTTAPPPVPPKPSSIPSGL----------------- 2497
Query: 480 ESPEYAEEPRAEEVFTLPERKTKPPVAEKP-----PVARRPPSLVHKPPS---------- 524
VFT +KPP+A KP P + P+ +H P+
Sbjct: 2498 -------------VFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTL 2544
Query: 525 ---VPEEYALTSPTLAMPP---RSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAP 578
+Y L SPT + P +SS + ++ L ++Y V+ P + +P +S+A
Sbjct: 2545 NLVTSADYKLPSPTSPLSPHSNKSSPRFSKSL-TETYVVITLPS-----EPGTPTDSSAS 2598
Query: 579 SSLVFTPFASSS 590
++ P S S
Sbjct: 2599 QAITSWPLGSPS 2610
Score = 38.1 bits (87), Expect = 0.028
Identities = 108/535 (20%), Positives = 191/535 (35%), Gaps = 87/535 (16%)
Query: 162 STSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPE 221
+T+S S S+ S +++A ++ SK+ KKP P + +L
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA----PEPKKPPPLVKQPTL---------H 713
Query: 222 GGSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGD 281
G + Q P++ LS S P Q + + K + K
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP------------KMVK 761
Query: 282 TYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPG 341
L SSS+AT I ++VQ +E +P ++ ++ + S P G
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP-----------LKTDSAKPSQSFPPTG 810
Query: 342 LMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPK- 400
S + S++ P P S S + H P S S + V P +K P + + PK
Sbjct: 811 --EKVSPFDSKA-IPRPA-SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866
Query: 401 --SRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNP--NQPIMPM 456
+ P P +G ++ ++ + S F + L T+ +QP P
Sbjct: 867 DAKPMPKGSPTPPGPR-PTAGQTVPTPQQSPKPQEQSR-RFSLNLGSITDAPKSQPTTPQ 924
Query: 457 VTQSDLRSVRLRSVSKS--EPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARR 514
T + +L S ++ S P ++ P ++ P +PP ++
Sbjct: 925 ETVTG----KLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA--PAPSQPPTSQG 978
Query: 515 PPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVR---KPKPSSFPDGRS 571
PP + P P A + P + + P + + TV R + KP D +S
Sbjct: 979 PPKSTGQAPPAP---AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS 1035
Query: 572 ----PGESTAPSSLVFTPFASSSDAFFS-----GTQQPPQGSVEDE-------------G 609
P ++ P+ L +P S+ G++ PP + E
Sbjct: 1036 LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPT 1095
Query: 610 PKVRVLPERISL--QSQEEAEKKKGKI--PPPVPKKPSVLYLPLTSPTAQMEAYV 660
P + + E + L Q+Q + G I PP P P +P+ + ++ + V
Sbjct: 1096 PHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAV 1150
Score = 34.3 bits (77), Expect = 0.41
Identities = 67/270 (24%), Positives = 103/270 (38%), Gaps = 44/270 (16%)
Query: 247 SHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGS 306
S P P IP P +TQ TD T SL+SS T V S
Sbjct: 2506 SKPPIAPKPVIPQL--PTTTQKP-----TDIHPKPTGLSLTSSMTLN--LVTSADYKLPS 2556
Query: 307 SESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTL 366
S SP +++++ S+ I+ P P +P+ +SQ+ T P S
Sbjct: 2557 PTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG---TPTDSSASQAITSWPLGS----- 2608
Query: 367 GHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRS 426
P V V PV S +PP + +E +P++S +SG ++ S
Sbjct: 2609 ----PSKDLVSVEPVF----SVVPPVTAVE----------IPISSEQTFYISG-ALQTFS 2649
Query: 427 KTKVSRHHSETNFGVKLAQ-KTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDI------ 479
T V+ S + Q T T+S SV L S+S + P + +
Sbjct: 2650 ATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIH 2709
Query: 480 -ESPEYAEEPRAEEVFTLPERKTKPPVAEK 508
E P+Y E+ + + V + + +T P V K
Sbjct: 2710 LEKPQYKEDGKLQLVGDVIDLRTVPKVEVK 2739
Score = 32.3 bits (72), Expect = 1.6
Identities = 43/201 (21%), Positives = 78/201 (38%), Gaps = 36/201 (17%)
Query: 523 PSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFP--DGRSPGESTAPSS 580
PS P+ T+P S++ + P PQ + PK + P D E P
Sbjct: 654 PSSPQPKLKTAPVTTT---SAVSKSSPQPQQT-----SPKKDAAPKQDLSKAPEPKKPPP 705
Query: 581 LVFTPFASSSDAFFSGTQQPPQG-SVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVP 639
LV P S + + +QPP+ S+ P P+ S+ S+++ K + P
Sbjct: 706 LVKQPTLHGSPS--AKAKQPPEADSLSKPAP-----PKEPSVPSEQD----KAPVADDKP 754
Query: 640 KKPSVLYLPLTS-------------PTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDL 686
K+P ++ P T P++++++ E P + + P TG+ +
Sbjct: 755 KQPKMVK-PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 687 QSLGQRVTSTPQADSEREASP 707
+ P +DS+ + P
Sbjct: 814 SPFDSKAIPRPASDSKIISHP 834
Score = 31.6 bits (70), Expect = 2.7
Identities = 37/112 (33%), Positives = 46/112 (41%), Gaps = 9/112 (8%)
Query: 595 SGTQQPPQ-GSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLT--S 651
S TQ P + K R P I S A+ P P PK P VLY P++ S
Sbjct: 3573 SDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP-PKSPKVLYSPISPLS 3631
Query: 652 PTAQME-AYVA-EPRLP--LSPIITLEED-TKCPATGDDLQSLGQRVTSTPQ 698
P +E A+V E LP +SP L D K P + QR S P+
Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK 3683
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 51.2 bits (121), Expect = 3e-06
Identities = 92/382 (24%), Positives = 141/382 (36%), Gaps = 78/382 (20%)
Query: 336 PGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPP---SSSVRVRPV--VPERKSSLP 390
P + PG PS ++ P+ + P P S+ +PV K P
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Query: 391 PT-SPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNP 449
PT SP K P S+ LP T P + + + + + K + +E V NP
Sbjct: 570 PTVSPSAKQPPSQ---GLPKTICPLCNTTELLLHVPEKANFNTC-TECQTTVCSLCGFNP 625
Query: 450 NQPI-----------------------MPMVTQSDLRSVRLRS---VSKSEPEDDIESPE 483
N + +P Q L++ + + VSKS P+ SP+
Sbjct: 626 NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPK 685
Query: 484 YAEEPRAEEVFTLPERKTKPPVAEKPPV-------ARRPPSL--VHKP-----PSVPEEY 529
P+ +++ PE K PP+ ++P + A++PP + KP PSVP E
Sbjct: 686 KDAAPK-QDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Query: 530 -------------ALTSPTLAMPPRSSIQHARPLPQDSY--TVVRKPKPSSFPDGRSPGE 574
+ PT + SS +P K P D P +
Sbjct: 745 DKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ 804
Query: 575 STAPSSLVFTPFASSS---DAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKK 631
S P+ +PF S + A S P S E +G K +V P +Q +EE +K +
Sbjct: 805 SFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK-QVDP----VQKKEEPKKAQ 859
Query: 632 GKIPPPVPKKPSVLYLPLTSPT 653
K+ P KP +P SPT
Sbjct: 860 TKMSP----KPDAKPMPKGSPT 877
Score = 43.9 bits (102), Expect = 5e-04
Identities = 103/430 (23%), Positives = 149/430 (34%), Gaps = 104/430 (24%)
Query: 305 GSSESLASPSTSRATTPSQLSIEVEAREISS-----PGRPPGLMSPSSGYSSQSETPTPT 359
GS A P+ A SQLS E E R+I++ G P G + P++ +E+P+
Sbjct: 30 GSPSHTAIPAGMEADL-SQLS-EEERRQIAAVMSRAQGLPKGSVPPAA-----AESPSMH 82
Query: 360 VSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSG 419
L H P S RP P R + P S R LP S + L
Sbjct: 83 RKQELDSSHPPKQSG----RPPDPGRPAQ-PGLSKSRTTDTFRSEQKLPGRSPSTISLK- 136
Query: 420 MSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMP-MVTQSDLRSVRLRSVSKSEPEDD 478
+S+T + H + +MP +++ + S V+K P D
Sbjct: 137 ---ESKSRTDLKEEHKSS---------------MMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 479 IESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHK--------------PPS 524
I E ++E ++ + + + KP KPP+ ++PP + K P S
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 525 V----PEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSP----GEST 576
+ PE+ P P IQ PQ + + + +S P + GES
Sbjct: 239 ISSQQPEKIKSQPPGTGKP----IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 577 APSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPP 636
PS P S QQP G + P E+++
Sbjct: 295 KPS----LPSPSKPP-----IQQPTPGKPPAQQP------------GHEKSQ-------- 325
Query: 637 PVPKKPSVLYLPLTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTST 696
P P KP LT P AQ V P P TK PA Q LG
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQP-------PGTTKPPA-----QPLGPAKPPA 373
Query: 697 PQADSEREAS 706
Q SE+ +S
Sbjct: 374 QQTGSEKPSS 383
Score = 38.9 bits (89), Expect = 0.017
Identities = 73/312 (23%), Positives = 111/312 (35%), Gaps = 74/312 (23%)
Query: 307 SESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTV-SMSLT 365
S +A P + +T S E +E + P G SPS SS P P S SL
Sbjct: 2345 SSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSG--SPS--VSSLPAKPRPFFRSSSLD 2400
Query: 366 LGHLPPPSSSVRVRPVVPERKSSLPPTSPMEK-----FPKSRLSFDLPLTSS-PNLDLSG 419
+ PPP P P PP P PK +L+ P+T++ P D
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD--- 2457
Query: 420 MSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDI 479
+++ T V R + ++ P P P S L
Sbjct: 2458 -AVTTLETTAVLRSNGLPV--TRICTTAPPPVPPKPSSIPSGL----------------- 2497
Query: 480 ESPEYAEEPRAEEVFTLPERKTKPPVAEKP-----PVARRPPSLVHKPPS---------- 524
VFT +KPP+A KP P + P+ +H P+
Sbjct: 2498 -------------VFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTL 2544
Query: 525 ---VPEEYALTSPTLAMPP---RSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAP 578
+Y L SPT + P +SS + ++ L ++Y V+ P + +P +S+A
Sbjct: 2545 NLVTSADYKLPSPTSPLSPHSNKSSPRFSKSL-TETYVVITLPS-----EPGTPTDSSAS 2598
Query: 579 SSLVFTPFASSS 590
++ P S S
Sbjct: 2599 QAITSWPLGSPS 2610
Score = 38.1 bits (87), Expect = 0.028
Identities = 108/535 (20%), Positives = 191/535 (35%), Gaps = 87/535 (16%)
Query: 162 STSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPE 221
+T+S S S+ S +++A ++ SK+ KKP P + +L
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKA----PEPKKPPPLVKQPTL---------H 713
Query: 222 GGSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGD 281
G + Q P++ LS S P Q + + K + K
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP------------KMVK 761
Query: 282 TYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPG 341
L SSS+AT I ++VQ +E +P ++ ++ + S P G
Sbjct: 762 PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP-----------LKTDSAKPSQSFPPTG 810
Query: 342 LMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPK- 400
S + S++ P P S S + H P S S + V P +K P + + PK
Sbjct: 811 --EKVSPFDSKA-IPRPA-SDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866
Query: 401 --SRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNP--NQPIMPM 456
+ P P +G ++ ++ + S F + L T+ +QP P
Sbjct: 867 DAKPMPKGSPTPPGPR-PTAGQTVPTPQQSPKPQEQSR-RFSLNLGSITDAPKSQPTTPQ 924
Query: 457 VTQSDLRSVRLRSVSKS--EPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARR 514
T + +L S ++ S P ++ P ++ P +PP ++
Sbjct: 925 ETVTG----KLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA--PAPSQPPTSQG 978
Query: 515 PPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVR---KPKPSSFPDGRS 571
PP + P P A + P + + P + + TV R + KP D +S
Sbjct: 979 PPKSTGQAPPAP---AKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS 1035
Query: 572 ----PGESTAPSSLVFTPFASSSDAFFS-----GTQQPPQGSVEDE-------------G 609
P ++ P+ L +P S+ G++ PP + E
Sbjct: 1036 LTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPT 1095
Query: 610 PKVRVLPERISL--QSQEEAEKKKGKI--PPPVPKKPSVLYLPLTSPTAQMEAYV 660
P + + E + L Q+Q + G I PP P P +P+ + ++ + V
Sbjct: 1096 PHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAV 1150
Score = 34.3 bits (77), Expect = 0.41
Identities = 67/270 (24%), Positives = 103/270 (38%), Gaps = 44/270 (16%)
Query: 247 SHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGS 306
S P P IP P +TQ TD T SL+SS T V S
Sbjct: 2506 SKPPIAPKPVIPQL--PTTTQKP-----TDIHPKPTGLSLTSSMTLN--LVTSADYKLPS 2556
Query: 307 SESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTL 366
S SP +++++ S+ I+ P P +P+ +SQ+ T P S
Sbjct: 2557 PTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG---TPTDSSASQAITSWPLGS----- 2608
Query: 367 GHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRS 426
P V V PV S +PP + +E +P++S +SG ++ S
Sbjct: 2609 ----PSKDLVSVEPVF----SVVPPVTAVE----------IPISSEQTFYISG-ALQTFS 2649
Query: 427 KTKVSRHHSETNFGVKLAQ-KTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDI------ 479
T V+ S + Q T T+S SV L S+S + P + +
Sbjct: 2650 ATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIH 2709
Query: 480 -ESPEYAEEPRAEEVFTLPERKTKPPVAEK 508
E P+Y E+ + + V + + +T P V K
Sbjct: 2710 LEKPQYKEDGKLQLVGDVIDLRTVPKVEVK 2739
Score = 32.3 bits (72), Expect = 1.6
Identities = 43/201 (21%), Positives = 78/201 (38%), Gaps = 36/201 (17%)
Query: 523 PSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFP--DGRSPGESTAPSS 580
PS P+ T+P S++ + P PQ + PK + P D E P
Sbjct: 654 PSSPQPKLKTAPVTTT---SAVSKSSPQPQQT-----SPKKDAAPKQDLSKAPEPKKPPP 705
Query: 581 LVFTPFASSSDAFFSGTQQPPQG-SVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVP 639
LV P S + + +QPP+ S+ P P+ S+ S+++ K + P
Sbjct: 706 LVKQPTLHGSPS--AKAKQPPEADSLSKPAP-----PKEPSVPSEQD----KAPVADDKP 754
Query: 640 KKPSVLYLPLTS-------------PTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDDL 686
K+P ++ P T P++++++ E P + + P TG+ +
Sbjct: 755 KQPKMVK-PTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKV 813
Query: 687 QSLGQRVTSTPQADSEREASP 707
+ P +DS+ + P
Sbjct: 814 SPFDSKAIPRPASDSKIISHP 834
Score = 31.6 bits (70), Expect = 2.7
Identities = 37/112 (33%), Positives = 46/112 (41%), Gaps = 9/112 (8%)
Query: 595 SGTQQPPQ-GSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLPLT--S 651
S TQ P + K R P I S A+ P P PK P VLY P++ S
Sbjct: 3573 SDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP-PKSPKVLYSPISPLS 3631
Query: 652 PTAQME-AYVA-EPRLP--LSPIITLEED-TKCPATGDDLQSLGQRVTSTPQ 698
P +E A+V E LP +SP L D K P + QR S P+
Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK 3683
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 50.8 bits (120), Expect = 4e-06
Identities = 77/371 (20%), Positives = 131/371 (35%), Gaps = 34/371 (9%)
Query: 336 PGRPPGLMSPSSGYSSQSE-TPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSP 394
P PP S+G S + T PT+S + PS + +P VP+ K ++P P
Sbjct: 540 PELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTE-KPTVPKEKPTIPTEKP 598
Query: 395 MEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIM 454
K + + P S + +I ++ T K T +P +
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTE--KPTV 656
Query: 455 PMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEE----PRAEEVFTLPERKTKPPVAEKPP 510
P T+ + S EP E P E P + ++ E EKP
Sbjct: 657 P--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS---TEKPT 711
Query: 511 VARRPPSLVHKPPSVPEEYALTSPTLAMPP--RSSIQHARPLPQDSYTVVRKPKPSSFPD 568
++ P++ + P++P E + SP P + +I +P KP+ P+
Sbjct: 712 ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPE 771
Query: 569 GRS-PGES-TAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRV----LPERISLQ 622
+ P E T P+ P + + T + ++ E P + + LP +
Sbjct: 772 KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTT 831
Query: 623 SQEEAEKKKGKIPPPVPK-------------KPSVLYLPLTSPTAQMEAYVAEPRLPLSP 669
S EE K+ P+ K KP++ LT PT ++ +P +P+
Sbjct: 832 SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
Query: 670 IITLEEDTKCP 680
E P
Sbjct: 892 TTISTEKLTIP 902
Score = 38.9 bits (89), Expect = 0.017
Identities = 87/444 (19%), Positives = 159/444 (35%), Gaps = 53/444 (11%)
Query: 11 PSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVSLNKVPPLVPK 70
P S GP+E+T +T + T + + + + PS ++ K P +P
Sbjct: 547 PVSSTGPSETTG-----------LTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT 595
Query: 71 EAATLLVARDNPAGCSGSAGYPERLIQQRHMP-ERPSKIGLLTSGTSRLETGPGGASRFR 129
E T ++ + P S P ++ +P E+P+ + + S T P
Sbjct: 596 EKPT--ISTEKPTIPSEKPNMPS---EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650
Query: 130 ERSLSVPTDSGTTDVD-----YDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQ 184
+VPT+ TT + +E E ++P S ++ E
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
Query: 185 HRRQRSKSISLRK----------AKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQ---R 231
+I K + +KP+ PT ++ ++P + PE + P ++
Sbjct: 711 TISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT-PTEKPTIS 769
Query: 232 PKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSST 291
P+ L + E + P P E T + ++ K + + +
Sbjct: 770 PEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPTTPTEETTISTEKPSIPMEKPTLPTE 827
Query: 292 ATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSS 351
T T+V E T S+E L P + + +I E IS P L P+ +
Sbjct: 828 ETTTSVEETTI---STEKLTIPMEKPTISTEKPTIPTEKPTIS----PEKLTIPTEKLTI 880
Query: 352 QSETPT-PTVSMSLTLGHLPPPSSSVRV---RPVVPERKSSLP---PTSPMEKFPKSRLS 404
+E PT P +++ L P+ + +P + K ++P PT P E+ S
Sbjct: 881 PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEK 940
Query: 405 FDLPLTSSPNLDLSGMSISIRSKT 428
+P T P + ++I T
Sbjct: 941 LTIP-TEKPTISPEKLTIPTEKPT 963
Score = 38.9 bits (89), Expect = 0.017
Identities = 77/368 (20%), Positives = 138/368 (37%), Gaps = 71/368 (19%)
Query: 296 TVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSET 355
T+I + S E P T + T P++ S + + ++P P + + S + T
Sbjct: 703 TIISTEKPTISPEKPTIP-TEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPTISPEKPT 760
Query: 356 PTPTVSMSLTLGHLPPPSSSVRV---RPVVPERKSSLP---PTSPMEKFPKSRLSFDLPL 409
TPT +++ L P+ + +P +P K ++ PT+P E+ S +P+
Sbjct: 761 -TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPM 819
Query: 410 TSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKT-NPNQPIMPMVTQSDLRSVRLR 468
P L + S+ T S + + + T + +P +P T+ S
Sbjct: 820 -EKPTLPTEETTTSVEETTI-----STEKLTIPMEKPTISTEKPTIP--TEKPTISPEKL 871
Query: 469 SVSKSEPEDDIESPEYAEEPR--AEEVFTLPERKTKPPVA-EKPPVARRPPSLVHKPPSV 525
++ + E P E + E T+P K P ++ EKP ++ P++ + P++
Sbjct: 872 TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEK--PTISPEKPTISTEKPTIPTEKPTI 929
Query: 526 PEEYA------LTSPT---LAMPPRSSIQHARP--------------------------- 549
P E LT PT P + +I +P
Sbjct: 930 PTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEK 989
Query: 550 --LPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSS--DAFFSGTQQPPQGSV 605
+P + T +R P PS +T ++LV +P A S+ + GT + S
Sbjct: 990 PTIPTEKLTALRPPHPSP--------TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
Query: 606 EDEGPKVR 613
E P R
Sbjct: 1042 ERCPPNAR 1049
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 50.8 bits (120), Expect = 4e-06
Identities = 77/371 (20%), Positives = 131/371 (35%), Gaps = 34/371 (9%)
Query: 336 PGRPPGLMSPSSGYSSQSE-TPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSP 394
P PP S+G S + T PT+S + PS + +P VP+ K ++P P
Sbjct: 540 PELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTE-KPTVPKEKPTIPTEKP 598
Query: 395 MEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIM 454
K + + P S + +I ++ T K T +P +
Sbjct: 599 TISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTE--KPTV 656
Query: 455 PMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEE----PRAEEVFTLPERKTKPPVAEKPP 510
P T+ + S EP E P E P + ++ E EKP
Sbjct: 657 P--TEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIIS---TEKPT 711
Query: 511 VARRPPSLVHKPPSVPEEYALTSPTLAMPP--RSSIQHARPLPQDSYTVVRKPKPSSFPD 568
++ P++ + P++P E + SP P + +I +P KP+ P+
Sbjct: 712 ISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPE 771
Query: 569 GRS-PGES-TAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRV----LPERISLQ 622
+ P E T P+ P + + T + ++ E P + + LP +
Sbjct: 772 KLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTT 831
Query: 623 SQEEAEKKKGKIPPPVPK-------------KPSVLYLPLTSPTAQMEAYVAEPRLPLSP 669
S EE K+ P+ K KP++ LT PT ++ +P +P+
Sbjct: 832 SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891
Query: 670 IITLEEDTKCP 680
E P
Sbjct: 892 TTISTEKLTIP 902
Score = 38.9 bits (89), Expect = 0.017
Identities = 87/444 (19%), Positives = 159/444 (35%), Gaps = 53/444 (11%)
Query: 11 PSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNSWVSLNKVPPLVPK 70
P S GP+E+T +T + T + + + + PS ++ K P +P
Sbjct: 547 PVSSTGPSETTG-----------LTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT 595
Query: 71 EAATLLVARDNPAGCSGSAGYPERLIQQRHMP-ERPSKIGLLTSGTSRLETGPGGASRFR 129
E T ++ + P S P ++ +P E+P+ + + S T P
Sbjct: 596 EKPT--ISTEKPTIPSEKPNMPS---EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTIS 650
Query: 130 ERSLSVPTDSGTTDVD-----YDEEQKANEACALPFASTSSEGSNSADNIASLSAQQEAQ 184
+VPT+ TT + +E E ++P S ++ E
Sbjct: 651 TEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKP 710
Query: 185 HRRQRSKSISLRK----------AKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQ---R 231
+I K + +KP+ PT ++ ++P + PE + P ++
Sbjct: 711 TISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT-PTEKPTIS 769
Query: 232 PKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSST 291
P+ L + E + P P E T + ++ K + + +
Sbjct: 770 PEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPTTPTEETTISTEKPSIPMEKPTLPTE 827
Query: 292 ATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSS 351
T T+V E T S+E L P + + +I E IS P L P+ +
Sbjct: 828 ETTTSVEETTI---STEKLTIPMEKPTISTEKPTIPTEKPTIS----PEKLTIPTEKLTI 880
Query: 352 QSETPT-PTVSMSLTLGHLPPPSSSVRV---RPVVPERKSSLP---PTSPMEKFPKSRLS 404
+E PT P +++ L P+ + +P + K ++P PT P E+ S
Sbjct: 881 PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEK 940
Query: 405 FDLPLTSSPNLDLSGMSISIRSKT 428
+P T P + ++I T
Sbjct: 941 LTIP-TEKPTISPEKLTIPTEKPT 963
Score = 38.9 bits (89), Expect = 0.017
Identities = 77/368 (20%), Positives = 138/368 (37%), Gaps = 71/368 (19%)
Query: 296 TVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSET 355
T+I + S E P T + T P++ S + + ++P P + + S + T
Sbjct: 703 TIISTEKPTISPEKPTIP-TEKPTIPTEKST-ISPEKPTTPTEKPTIPTEKPTISPEKPT 760
Query: 356 PTPTVSMSLTLGHLPPPSSSVRV---RPVVPERKSSLP---PTSPMEKFPKSRLSFDLPL 409
TPT +++ L P+ + +P +P K ++ PT+P E+ S +P+
Sbjct: 761 -TPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPM 819
Query: 410 TSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKT-NPNQPIMPMVTQSDLRSVRLR 468
P L + S+ T S + + + T + +P +P T+ S
Sbjct: 820 -EKPTLPTEETTTSVEETTI-----STEKLTIPMEKPTISTEKPTIP--TEKPTISPEKL 871
Query: 469 SVSKSEPEDDIESPEYAEEPR--AEEVFTLPERKTKPPVA-EKPPVARRPPSLVHKPPSV 525
++ + E P E + E T+P K P ++ EKP ++ P++ + P++
Sbjct: 872 TIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEK--PTISPEKPTISTEKPTIPTEKPTI 929
Query: 526 PEEYA------LTSPT---LAMPPRSSIQHARP--------------------------- 549
P E LT PT P + +I +P
Sbjct: 930 PTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEK 989
Query: 550 --LPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSS--DAFFSGTQQPPQGSV 605
+P + T +R P PS +T ++LV +P A S+ + GT + S
Sbjct: 990 PTIPTEKLTALRPPHPSP--------TATGLAALVMSPHAPSTPMTSVILGTTTTSRSST 1041
Query: 606 EDEGPKVR 613
E P R
Sbjct: 1042 ERCPPNAR 1049
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 50.4 bits (119), Expect = 6e-06
Identities = 80/321 (24%), Positives = 116/321 (36%), Gaps = 39/321 (12%)
Query: 344 SPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPT--SPMEKFPKS 401
S SG + TP S S+ L PP+ V P P PPT S M + +
Sbjct: 677 SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPP-----PPTPGSAMAQLKPA 731
Query: 402 RLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSD 461
+ LP S+P L + ++ L + P +P++ + +
Sbjct: 732 PCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP-KPLVTIPAPTS 790
Query: 462 LRSVRLRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPV--------AR 513
++V + P P ++P + P T PPV PP A+
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPT-PPVPVPPPTLPKQQSFCAK 849
Query: 514 RPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPL-----PQDSYTVVRKPK--PSSF 566
PPS + PSV ++ A P PP Q +P+ PQ V KPK PSS
Sbjct: 850 PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSI 909
Query: 567 PDGRSPGESTAP--SSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQ 624
P SP P SSLVF P S P P P++ +
Sbjct: 910 P-VPSPDFPPPPPESSLVFPPPPPS----------PVPAPPPPPPPTASPTPDKSGSPGK 958
Query: 625 EEAEKKK--GKIPPPVPKKPS 643
+ ++ GK PPP P++ S
Sbjct: 959 KTSKTSSPGGKKPPPTPQRNS 979
Score = 50.4 bits (119), Expect = 6e-06
Identities = 72/330 (21%), Positives = 113/330 (34%), Gaps = 25/330 (7%)
Query: 336 PGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSS------VRVRPVVPERKSSL 389
P PP P+ G + P P PPP +V P P +
Sbjct: 710 PPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPI 769
Query: 390 PPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNP 449
P P + PK ++ P ++ + + V + F + P
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP 829
Query: 450 NQPI-MPMVTQSDLRSVRLR-SVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAE 507
P+ +P T +S + S P + ++ P + + KP A
Sbjct: 830 TPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPAN 889
Query: 508 KPPVARRPPSLVHKPPSVPEEYALTSPTL-AMPPRSSIQHARPLPQDSYTVVRKPKPSSF 566
P + PP++ KP P + SP PP SS+ P P P P++
Sbjct: 890 VAP--QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS 947
Query: 567 P---DGRSPGESTAPSSLVF------TPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPE 617
P SPG+ T+ +S TP +SS SG + P E + P V L
Sbjct: 948 PTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP-----EPKRPSVDSLVS 1002
Query: 618 RISLQSQEEAEKKKGKIPPPVPKKPSVLYL 647
+ + ++ + K+ PP P KP L L
Sbjct: 1003 KFTPPAESGSPSKETLPPPAAPPKPGKLNL 1032
>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
sapiens]
Length = 834
Score = 50.1 bits (118), Expect = 7e-06
Identities = 95/438 (21%), Positives = 148/438 (33%), Gaps = 45/438 (10%)
Query: 306 SSESLASPSTSRATTPSQLSIEVEAREI---SSPGRPPGLMSPSSGYSSQSETPTPTVSM 362
SS +SP++SR+ TP + + ++ E+ SS P S G + TP +
Sbjct: 17 SSSPFSSPASSRSQTPERPAKKIREEEMCHHSSSSTPLAADKESQGEKAADTTPRKKQNS 76
Query: 363 SLTLGHLPPPSSSVRVRPV--VPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGM 420
+ P SS R R V +P R+ P + S + DL L +L
Sbjct: 77 N---SQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKKASLQWFNQ 133
Query: 421 SISIRSKTKVSRHHSET--------NFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSK 472
++ +S S +ET F + A +P ++ T L S++
Sbjct: 134 ALEDKSDA-ASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPSTNPLLESLKKMQTPP 192
Query: 473 SEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVA---EKPPVARRPPSLVHKPPS----- 524
S P PE A E + PP+ PP PS PP+
Sbjct: 193 SLP----PCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSFDSNPPTTLLGL 248
Query: 525 VPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSF--PDGRSPGESTAP---- 578
+P + + PP + PQ + PK S SP AP
Sbjct: 249 IPAPSMVPATDTKAPPTLQAE-TTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASS 307
Query: 579 SSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPV 638
+S +F P ++ PP SV P LP S + PP
Sbjct: 308 ASPMFKPIFTAPPKSEKEGPTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPAS 367
Query: 639 PKKPSVLYLPLTSP------TAQMEAYVAEPRLPLSPIITLEEDTKC---PATGDDLQSL 689
P+ + T+P TA + +A ++PI + T PA G + S+
Sbjct: 368 VPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV 427
Query: 690 GQRVTSTPQADSEREASP 707
ST + + + P
Sbjct: 428 SSSSVSTTTSTATAASQP 445
Score = 37.0 bits (84), Expect = 0.063
Identities = 107/545 (19%), Positives = 175/545 (32%), Gaps = 112/545 (20%)
Query: 151 KANEACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVS 210
K N + PF+S +S S + + A ++E H S ++ K + +
Sbjct: 12 KRNGPSSSPFSSPASSRSQTPERPAKKIREEEMCHHSSSSTPLAADKESQGEKAADTTPR 71
Query: 211 LVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQGHHSSHPDAQ--GHPAIPNHKDPESTQF 268
++ G S QR + + L +G + P G+ D E +
Sbjct: 72 KKQNSNSQSTPGSSG----QRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEK-KA 126
Query: 269 SHHWYLTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQL---- 324
S W+ Q+L S A +V E + S + P+ + A+ P+ L
Sbjct: 127 SLQWF---------NQALEDKSDAASNSVTETPPITQPSFTFTLPAAAPASPPTSLLAPS 177
Query: 325 ----------------------SIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSM 362
S E SP + P L+ P S P+ S
Sbjct: 178 TNPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPNLLPPLGLSQSGPPGLLPSPSF 237
Query: 363 -----SLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDL 417
+ LG +P PS +VP + PPT E K + TS+P+
Sbjct: 238 DSNPPTTLLGLIPAPS-------MVPATDTKAPPTLQAETTTKPQ------ATSAPS--- 281
Query: 418 SGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPED 477
FG Q T+P+ P P + + S + + + P+
Sbjct: 282 -------------PAPKQSFLFG---TQNTSPSSPAAPAASSA---SPMFKPIFTAPPKS 322
Query: 478 DIESPEYAEEPRAEEVFTLPERKTKPPVAEK-------------PPVARRPPSLVHKPPS 524
+ E P P T P + P PP + P+ K +
Sbjct: 323 EKEGP---TPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTT 379
Query: 525 VPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFT 584
P T+ L S+ P+ S + KP +F G + S++ S+ T
Sbjct: 380 TPATAPTTTAPLFTGLASATSAVAPITSASPSTDSASKP-AFGFGINSVSSSSVSTTTST 438
Query: 585 PFASSSDAFFSGTQ------QPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPV 638
A+S F Q P GS+ G K LP ++ + ++ +P V
Sbjct: 439 ATAASQPFLFGAPQASAASFTPAMGSIFQFG-KPPALPTTTTVTTFSQS------LPTAV 491
Query: 639 PKKPS 643
P S
Sbjct: 492 PTATS 496
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.1 bits (118), Expect = 7e-06
Identities = 67/291 (23%), Positives = 108/291 (37%), Gaps = 28/291 (9%)
Query: 287 SSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPS 346
S+ S + + + T V GS +SL+S + ATT S + +PG P
Sbjct: 2453 SAFSDQSRCLIAQTTPVAGS-QSLSSGAV--ATTTSSAGDHNGMLSVPAPGVP------- 2502
Query: 347 SGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFD 406
+S E P T + PS+ ++P R SS +S S S
Sbjct: 2503 --HSDVGEPPASTGAQQ--------PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552
Query: 407 LPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVR 466
+ S + D G S+ ++ + + R S T + ++ P +P + S
Sbjct: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612
Query: 467 LRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVP 526
S S S S + + + + P A+ P A P+ KPP P
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP--P 2670
Query: 527 EEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTA 577
E SP P S++ +R L SY+ V + +PS P R S++
Sbjct: 2671 GERRSRSPR---KPIDSLRDSRSL---SYSPVERRRPSPQPSPRDQQSSSS 2715
Score = 49.7 bits (117), Expect = 9e-06
Identities = 131/579 (22%), Positives = 206/579 (35%), Gaps = 107/579 (18%)
Query: 113 SGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSSEGSNSAD 172
SG+S S+ R RS S P E K + + S SS S +
Sbjct: 724 SGSSSERKNKSRTSQRRSRSNSSP------------EMKKSRISSRRSRSLSSPRSKAKS 771
Query: 173 NIA---SLSA-----QQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGS 224
++ SLS +Q++Q +RS+S S + K +PP RS + P+ S
Sbjct: 772 RLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRS----RSSSSPPPKQKS 827
Query: 225 ALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQ 284
P Q S S H S P QG P + T + +S +
Sbjct: 828 KTPSRQSHSS---SSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCF----ESSPDPE 880
Query: 285 SLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPG----RPP 340
S + + + +V+ S+ SPS S + P +I + R+ S G P
Sbjct: 881 LKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAI-ISPRQRSHSGSSSPSPS 939
Query: 341 GLMSPSSGYSSQSETPTPTVSMSL--TLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKF 398
+ S ++ S+S +P V L H S +V+P P R+S SP +
Sbjct: 940 RVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP---Y 996
Query: 399 PKSRLSFDLPLTSSPNLDLSGM-------------------SISIRSKTKVSRHHSETNF 439
PK + + P LSG S+S+ + K S E+ F
Sbjct: 997 PKVKAQ------TPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYF 1050
Query: 440 GVKLAQ-----KTNP---NQPIMPMVTQSDLRSVRLRSVSKSEPEDDIESPEYAEEPRAE 491
GV Q +T+P + P V QS S L+S S++ P+ + P E
Sbjct: 1051 GVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG---GRSRSSSPVTE 1107
Query: 492 EVFTLPERKTKPPVAEKP-------PVARRPPSLVHKPPSVPE---------EYALTSPT 535
P R+ + + P P R S P+V E A +
Sbjct: 1108 LASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEK 1167
Query: 536 LAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFS 595
+A+PP+ + P +D + S FP P SSLVF + S
Sbjct: 1168 MALPPQEDATASPPRQKDKF--------SPFPVQDRP-----ESSLVFKDTLRTPPRERS 1214
Query: 596 GTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKI 634
G P+ ++ E + ++ E++E+ G+I
Sbjct: 1215 GAGSSPETKEQNSALPTSSQDEEL-MEVVEKSEEPAGQI 1252
Score = 42.7 bits (99), Expect = 0.001
Identities = 88/356 (24%), Positives = 132/356 (37%), Gaps = 56/356 (15%)
Query: 36 PSATSQSNQVNENGKNPSCGNSWV-SLNKVPPLVPKEAATLLVARDNPAGCSGSA-GYPE 93
PSA SQS +E +PS S + +PP A+D P SA
Sbjct: 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPP-----------AQDQPRSPVPSAFSDQS 2459
Query: 94 RLIQQRHMPERPSKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKAN 153
R + + P S+ L+SG T G LSVP G D E
Sbjct: 2460 RCLIAQTTPVAGSQ--SLSSGAVATTTSSAGD---HNGMLSVPA-PGVPHSDVGE----- 2508
Query: 154 EACALPFASTSSEGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVK 213
P AST A ++L+A Q A+ RR S S S + S + S S
Sbjct: 2509 -----PPAST------GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSS--- 2554
Query: 214 DEPGLLPEGGSALPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWY 273
GS+ D SL + E P A+ + PE T
Sbjct: 2555 -------SSGSS-SSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKR--- 2603
Query: 274 LTDWKSGDTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEA-RE 332
+S + S SSSS+++ ++ + SS S +S S+S +++PS +A +
Sbjct: 2604 --KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
Query: 333 ISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSS 388
+SP +PP P S P ++ S +L + P +P +++SS
Sbjct: 2662 PASPKKPP----PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSS 2713
Score = 42.4 bits (98), Expect = 0.002
Identities = 85/366 (23%), Positives = 132/366 (36%), Gaps = 44/366 (12%)
Query: 307 SESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYS----------SQSETP 356
S + A SR+ TP++ S +R + GR +P G S S S TP
Sbjct: 660 SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRS-RTPRRGRSRSRSLVRRGRSHSRTP 718
Query: 357 ---------TPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDL 407
+ + S T +SS ++ + S +SP K KSRLS
Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK-AKSRLSLRR 777
Query: 408 PLT-SSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVR 466
L+ SSP + RS++ S+ +++ + ++ ++ P T S
Sbjct: 778 SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR----- 832
Query: 467 LRSVSKSEPEDDIESPEYAEE-----PRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHK 521
+S S S P ++S + P+A E P+R++ + P + R PS
Sbjct: 833 -QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSC 891
Query: 522 PPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSL 581
S P ++P P RSS PQ + P+ S SP S S
Sbjct: 892 SGSSPPRVKSSTPPRQSPSRSS------SPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT 945
Query: 582 VFTPFASSSDAFFSGTQQ---PPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPV 638
TP S S + S + P P +V PE QS + K+
Sbjct: 946 --TPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT 1003
Query: 639 PKKPSV 644
P PS+
Sbjct: 1004 PPGPSL 1009
Score = 42.4 bits (98), Expect = 0.002
Identities = 151/706 (21%), Positives = 231/706 (32%), Gaps = 117/706 (16%)
Query: 46 NENGKNPSCGNSWVSLNKVPPLVPKEAATLLVARDNPAGCSGSAGYPERLIQQRHMPERP 105
+ G+ PS S S P PK +R +P + S P R R PE
Sbjct: 1641 SSKGRGPSPEGS-SSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRR-SSRSSPELT 1698
Query: 106 SKIGLLTSGTSRLETGPGGASRFRERSLSVPTDSGTTDVDYDEEQKANEACALPFASTSS 165
K L S + P SR R P+ S + + + + P T+S
Sbjct: 1699 RKARLSRRSRSA-SSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTS 1757
Query: 166 EGSNSADNIASLSAQQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSA 225
S Q ++ R +R K+ + R+ + S + S + S
Sbjct: 1758 RRGRSPS--PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR------SRSR 1809
Query: 226 LPKDQRPKSLCLSLEHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQS 285
+ + +R S G+HS P Q ES++ S ++ T +
Sbjct: 1810 VTRRRRGGS--------GYHSRSPARQ-----------ESSRTSSRRRRGRSRTPPTSRK 1850
Query: 286 LSSSSTATGTTVIECTQVQGSSESLASPST---SRATTPSQLSIEVEAREISSP------ 336
S S T+ S S ASP+T SR+ TP L +R +SP
Sbjct: 1851 RSRSRTSPAPWK--------RSRSRASPATHRRSRSRTP--LISRRRSRSRTSPVSRRRS 1900
Query: 337 --------GRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSS 388
R SP S S+S TP T S + S R PV R S
Sbjct: 1901 RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRS 1960
Query: 389 LPP----------TSPM-EKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTK---VSRHH 434
P TSP+ + +SR S P+T + + RS+++ V+R
Sbjct: 1961 RTPPVTRRRSRSRTSPITRRRSRSRTS---PVTRRRSRSRTSPVTRRRSRSRTSPVTRRR 2017
Query: 435 SETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSE-------PEDDIESPEYAEE 487
S + + +++ P++P + +R S+S SP
Sbjct: 2018 SRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRR 2077
Query: 488 PRAEEVFTLPERKTKPPVAEKPPVARRPP--------SLVHKPPSVPEEY-ALTSPTLAM 538
A + R PP +R PP S +P P SP +
Sbjct: 2078 RSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLE 2137
Query: 539 PPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSGTQ 598
P SS L Q +++ P P PD + ++ P + + A + A GT
Sbjct: 2138 PLGSSRTPMSVLQQAGGSMMDGPGP-RIPDHQ---RTSVPENHAQSRIALALTAISLGTA 2193
Query: 599 QPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVP----KKPSVLYLPLTSPTA 654
+PP S+ G R+ ++P PVP + L P A
Sbjct: 2194 RPPP-SMSAAGLAARM-----------------SQVPAPVPLMSLRTAPAANLASRIPAA 2235
Query: 655 QMEAY-VAEPRLPLSPIITLEEDTKCPATGDDLQSLGQRVTSTPQA 699
A +A R P P D++ PA + R P A
Sbjct: 2236 SAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSA 2281
Score = 39.3 bits (90), Expect = 0.013
Identities = 76/309 (24%), Positives = 112/309 (36%), Gaps = 82/309 (26%)
Query: 180 QQEAQHRRQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALPKDQRPKSLCLSL 239
+++ ++++ +S S K +K SP +S KD+ + PK +R
Sbjct: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRR-------- 259
Query: 240 EHQGHHSSHPDAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGTTVIE 299
H S+ D+ S DT +S S S+ A T
Sbjct: 260 ---AHRSTSADSA-------------------------SSSDTSRSRSRSAAAKTHT--- 288
Query: 300 CTQVQGSSESLAS--------PSTSRATTPSQ--LSIEVEAREISSP---------GRPP 340
T + G S S AS P + TT +Q S E ++ SSP +
Sbjct: 289 -TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA 347
Query: 341 GLMSPSSGYSSQS-ETPTPTVSMSLTLGHLPPP--SSSVRVRPVVPERKSS-----LPPT 392
SPS SS E P PT ++ G P P ++ + PV P ++S PP
Sbjct: 348 TRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPK 407
Query: 393 SPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQP 452
SP EK P+S S P + P TKVSRH S + K A ++
Sbjct: 408 SP-EKLPQSSSSESSPPSPQP--------------TKVSRHASSSPESPKPAPAPGSHRE 452
Query: 453 IMPMVTQSD 461
I T +
Sbjct: 453 ISSSPTSKN 461
Score = 35.8 bits (81), Expect = 0.14
Identities = 84/382 (21%), Positives = 141/382 (36%), Gaps = 59/382 (15%)
Query: 285 SLSSSSTATGTTVIEC----TQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPP 340
+L+S+ T T + T ++ +LASP T A PS +++ + P P
Sbjct: 2241 NLASARTPAIPTAVNLADSRTPAAAAAMNLASPRT--AVAPSAVNL-------ADPRTPT 2291
Query: 341 GLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPK 400
+G + TP ++SLT PP +++ P+ +S P
Sbjct: 2292 APAVNLAG----ARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHA- 2346
Query: 401 SRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQS 460
T+ N+ S + ++ + S + G L T+P P+ S
Sbjct: 2347 ---------TAPVNIAGSRTAAALAPASLTSARMAPALSGANL---TSPRVPLSAYERVS 2394
Query: 461 DLRSVRL--RSVSKSEPEDDIES---PEYAEEPRAEEVFTLPERKTKPPVAEKP----PV 511
S L R+ S++ P +S E A P + + P + PP ++P P
Sbjct: 2395 GRTSPPLLDRARSRTPPSAPSQSRMTSERAPSP-SSRMGQAPSQSLLPPAQDQPRSPVPS 2453
Query: 512 ARRPPS--LVHKPPSVPEEYALTSPTLAMPPRSSIQH----ARPLPQDSYTVVRKPKPSS 565
A S L+ + V +L+S +A S+ H + P P ++ V +P S+
Sbjct: 2454 AFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 566 FPDGRS------PGESTAPSSLVFTPFASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERI 619
S P + SS + +SSS + S + GS + E
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS-------EGS 2566
Query: 620 SLQSQEEAEKKKGKIPPPVPKK 641
SL Q E K+ P P PK+
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPKE 2588
Score = 33.1 bits (74), Expect = 0.91
Identities = 67/356 (18%), Positives = 123/356 (34%), Gaps = 47/356 (13%)
Query: 309 SLASPSTSRATTPSQLSIE-----VEAREISSPGRPPGLMSPSSGYSS-------QSETP 356
++A T+ A P+ L+ + ++SP P SG +S +S TP
Sbjct: 2351 NIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP 2410
Query: 357 TPTVSMS-LTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFP---------KSRLSFD 406
S S +T P PSS + P +S LPP + P + ++
Sbjct: 2411 PSAPSQSRMTSERAPSPSSRMGQAP----SQSLLPPAQDQPRSPVPSAFSDQSRCLIAQT 2466
Query: 407 LPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVR 466
P+ S +L ++ + S H+ + ++ +P Q
Sbjct: 2467 TPVAGSQSLSSGAVATTTSS---AGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 467 LRSVSKSEPEDDIESPEYAEEPRAEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVP 526
L+ + S + + + + +E + +P + + PS
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPS-- 2581
Query: 527 EEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPF 586
PT A P+ +++ RP + RK + SS S S++ SS +
Sbjct: 2582 -------PTPA--PKEAVREGRP--PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 587 ASSSDAFFSGTQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKP 642
+SSS + S + S P + LP+ S + E++ P+KP
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS-----PRKP 2681
Score = 32.0 bits (71), Expect = 2.0
Identities = 79/357 (22%), Positives = 127/357 (35%), Gaps = 49/357 (13%)
Query: 155 ACALPFASTSS-------EGSNSADNIASLSAQQEAQHR-------RQRSK------SIS 194
A AL AS +S G+N LSA + R R RS+ S S
Sbjct: 2358 AAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQS 2417
Query: 195 LRKAKKKPSPPTR-----SVSLVKDEPGLLPEGGSALPKDQRPKSLCLSLEHQGHHSSHP 249
+++ PSP +R S SL+ P + S +P +S CL + S
Sbjct: 2418 RMTSERAPSPSSRMGQAPSQSLL---PPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQS 2474
Query: 250 DAQGHPAIPNHKDPESTQFSHHWYLTDWKSGDTYQSLSSSSTATGT------TVIECTQV 303
+ G A S+ H+ L+ G + + +TG ++ +
Sbjct: 2475 LSSGAVATTT-----SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE 2529
Query: 304 QGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMS 363
+ SS S +S S+S +++ S S + SS L + +PTP +
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589
Query: 364 LTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSIS 423
+ G P P+ + R R R SS +S S S +SS + S S S
Sbjct: 2590 VREGRPPEPTPAKRKR-----RSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 424 IRSKTKVSRHHSETNFGVKLAQKTNPNQ-----PIMPMVTQSDLRSVRLRSVSKSEP 475
S ++ + +K P + P P+ + D RS+ V + P
Sbjct: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRP 2701
Score = 30.4 bits (67), Expect = 5.9
Identities = 67/300 (22%), Positives = 109/300 (36%), Gaps = 51/300 (17%)
Query: 314 STSRATTPSQLSIEVEA-----REISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGH 368
S+SR+ TP Q + + E SSP R S + S+SE+
Sbjct: 178 SSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK-------HR 230
Query: 369 LPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGM-------- 420
P P S + + +R S T+P K ++ S SS + S
Sbjct: 231 SPTPKSKRKSKDKKRKRSRS---TTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTH 287
Query: 421 --SISIRSKTKVSRHHSE----------TNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLR 468
+++ RS + S E T+ + +T QP P + + +
Sbjct: 288 TTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA 347
Query: 469 SVSKSEPEDDIESPEY-AEEPR-AEEVFTLPERKTKPPVAEKP--PVARRPPSLVHKPPS 524
+ PE PE A P AE P+ P++++P P + P+ PP
Sbjct: 348 TRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPK 407
Query: 525 VPEEYALTSPTLAMPPRSS----IQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSS 580
PE+ +S + + PP +HA P+ PKP+ P G S++P+S
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPE-------SPKPAPAP-GSHREISSSPTS 459
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,147,624
Number of Sequences: 37866
Number of extensions: 1988020
Number of successful extensions: 11997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 844
Number of HSP's that attempted gapping in prelim test: 8999
Number of HSP's gapped (non-prelim): 3048
length of query: 709
length of database: 18,247,518
effective HSP length: 109
effective length of query: 600
effective length of database: 14,120,124
effective search space: 8472074400
effective search space used: 8472074400
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.