Search of human proteins with 5902108

Search of human proteins with 5902108

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5902108 SRY-box 21 [Homo sapiens]
         (276 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5902108 SRY-box 21 [Homo sapiens]                                  558   e-159
gi|4759162 SRY-box 14 [Homo sapiens]                                  290   1e-78
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]       206   2e-53
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]             182   4e-46
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]       182   4e-46
gi|5902106 SRY-box 15 [Homo sapiens]                                  144   1e-34
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]        139   3e-33
gi|4507161 SRY-box 11 [Homo sapiens]                                  134   9e-32
gi|4507225 sex determining region Y [Homo sapiens]                    125   3e-29
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]      125   3e-29
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]       123   2e-28
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]       122   3e-28
gi|4557853 transcription factor SOX9 [Homo sapiens]                   122   4e-28
gi|11967991 SRY-box 17 [Homo sapiens]                                 120   1e-27
gi|8924248 SRY-box 18 [Homo sapiens]                                  113   2e-25
gi|13899269 SRY-box 7 [Homo sapiens]                                  112   4e-25
gi|41406089 SRY-box 13 [Homo sapiens]                                 103   2e-22
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo...   102   3e-22
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo...   102   3e-22
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo...   102   3e-22
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...    99   3e-21
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...    99   3e-21
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...    99   3e-21
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...    99   3e-21
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...    91   1e-18
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...    91   1e-18
gi|112421108 capicua homolog [Homo sapiens]                            79   3e-15
gi|24497554 homeobox A13 [Homo sapiens]                                65   6e-11
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]          61   9e-10
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa...    59   4e-09

>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score =  558 bits (1438), Expect = e-159
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE 60
           MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE
Sbjct: 1   MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE 60

Query: 61  AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG 120
           AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG
Sbjct: 61  AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG 120

Query: 121 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMA 180
           AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMA
Sbjct: 121 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMA 180

Query: 181 EISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNC 240
           EISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNC
Sbjct: 181 EISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNC 240

Query: 241 SAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL 276
           SAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL
Sbjct: 241 SAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL 276


>gi|4759162 SRY-box 14 [Homo sapiens]
          Length = 240

 Score =  290 bits (741), Expect = 1e-78
 Identities = 162/285 (56%), Positives = 190/285 (66%), Gaps = 54/285 (18%)

Query: 1   MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE 60
           MSKP DH+KRPMNAFMVWSR QRRKMAQENPKMHNSEISKRLGAEWKLL+E+EKRP+IDE
Sbjct: 1   MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE 60

Query: 61  AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG 120
           AKRLRA HMKEHPDYKYRPRRKPK LLKKD++ FP+PY LG     +   LKA AGL  G
Sbjct: 61  AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPY-LG-----DTDPLKA-AGLPVG 113

Query: 121 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLG---- 176
           A  G     LL+ PEK         AR F P ++A             PYSLLD      
Sbjct: 114 ASDG-----LLSAPEK---------ARAFLPPASA-------------PYSLLDPAQFSS 146

Query: 177 ---SKMAEI--SSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGN 231
               KM E+  + ++  LPYAS+LGY     GAF         + +    HTH+HPSP N
Sbjct: 147 SAIQKMGEVPHTLATGALPYASTLGYQN---GAF--------GSLSCPSQHTHTHPSPTN 195

Query: 232 PGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL 276
           PGY++PCNC+AW +  LQPP+AYIL PGM K  +DPY +A+A A+
Sbjct: 196 PGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM 240


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score =  206 bits (523), Expect = 2e-53
 Identities = 149/323 (46%), Positives = 172/323 (53%), Gaps = 60/323 (18%)

Query: 6   DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65
           D VKRPMNAFMVWSR QRRKMAQENPKMHNSEISKRLGAEWK+++E+EKRPFIDEAKRLR
Sbjct: 49  DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLR 108

Query: 66  AMHMKEHPDYKYRPRRKPKTLLKKDKFAFP---VPYGLGGVADAEHPALKAGAGLHA--- 119
           A+HMKEHPDYKYRPRRK KTLLKKDK++     +  G GG   A    +  G G  A   
Sbjct: 109 ALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQ 168

Query: 120 -------GAGGGLVPESLLAN---PEKAAAAAAAAA----ARVFFPQSAAAAAAAAAAAA 165
                   AGGG    +  AN   P   AAAAAAAA    A++ + Q   A  A   A  
Sbjct: 169 RLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQLAYGQHPGAGGAHPHAHP 228

Query: 166 A-------------GSPYSLLDLGS-----------KMAEISSSSSGLPYASSLGYPTAG 201
           A               P    D+G+            M+   S   GLPY ++     A 
Sbjct: 229 AHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAA 288

Query: 202 AGAFHGAAAAAAAAAAAA--------GGHTHSHPSPGNPGYMIPCNCSAWPSPG-LQPPL 252
            GA   +A AAAAAAAAA        G    S PS   P    P +  A P PG L+  +
Sbjct: 289 GGAHQNSAVAAAAAAAAASSGALGALGSLVKSEPSGSPPA---PAHSRA-PCPGDLREMI 344

Query: 253 AYILLPGMGKPQLDPYPAAYAAA 275
           +  L  G G    DP  AA AAA
Sbjct: 345 SMYLPAGEGG---DPAAAAAAAA 364



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 43/104 (41%), Positives = 50/104 (48%), Gaps = 25/104 (24%)

Query: 138 AAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLG- 196
           AAAAAAAAA      SA AAAAAAAAA++G+      LG+  + + S  SG P A +   
Sbjct: 280 AAAAAAAAAGGAHQNSAVAAAAAAAAASSGA------LGALGSLVKSEPSGSPPAPAHSR 333

Query: 197 -------------YPTAGAGAFHGAAAAAAAAAAAAGGHTHSHP 227
                        Y  AG G        AAAAAAAA    HS P
Sbjct: 334 APCPGDLREMISMYLPAGEGG-----DPAAAAAAAAQSRLHSLP 372


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score =  182 bits (461), Expect = 4e-46
 Identities = 88/120 (73%), Positives = 99/120 (82%), Gaps = 5/120 (4%)

Query: 6   DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65
           D VKRPMNAFMVWSR QRRKMAQENPKMHNSEISKRLGAEWKLL+E+EKRPFIDEAKRLR
Sbjct: 39  DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR 98

Query: 66  AMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGL 125
           A+HMKEHPDYKYRPRRK KTL+KKDK+  P     GG+      ++ +G G+ AG G G+
Sbjct: 99  ALHMKEHPDYKYRPRRKTKTLMKKDKYTLP-----GGLLAPGGNSMASGVGVGAGLGAGV 153


>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
          Length = 446

 Score =  182 bits (461), Expect = 4e-46
 Identities = 120/249 (48%), Positives = 147/249 (59%), Gaps = 24/249 (9%)

Query: 6   DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65
           D VKRPMNAFMVWSR QRRKMA ENPKMHNSEISKRLGA+WKLLT++EKRPFIDEAKRLR
Sbjct: 137 DRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLR 196

Query: 66  AMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGL 125
           A+HMKE+PDYKYRPRRK KTLLKKDK++ P      G A A   A  A A   +  G G 
Sbjct: 197 AVHMKEYPDYKYRPRRKTKTLLKKDKYSLPSGLLPPGAAAAAAAAAAAAAAASSPVGVGQ 256

Query: 126 VPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAA--------AAGSPYS-LLDLG 176
             ++       A  A +    ++ + Q  + ++     A         AG  YS ++  G
Sbjct: 257 RLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPPMHRYDMAGLQYSPMMPPG 316

Query: 177 SK----MAEISSSSSGLPYASSLGYPTAGAGAFHG---AAAAAAAAAAAA------GGHT 223
           ++    +A  ++++SG  Y       TA A A +G   A AAAAAAAAAA      G   
Sbjct: 317 AQSYMNVAAAAAAASG--YGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVV 374

Query: 224 HSHPSPGNP 232
            S PS   P
Sbjct: 375 KSEPSSPPP 383



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 35/117 (29%), Positives = 41/117 (35%), Gaps = 9/117 (7%)

Query: 113 AGAGLHAGAGGGLVPESLLA-------NPEKAAAAAAAAAARVFFPQ-SAAAAAAAAAAA 164
           A A   A   GG+ P +  A        P  AAAAAAAAAA    P  S   +  ++   
Sbjct: 324 AAAAAAASGYGGMAPSATAAAAAAYGQQPATAAAAAAAAAAMSLGPMGSVVKSEPSSPPP 383

Query: 165 AAGSPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGG 221
           A  S      LG     IS        A+    P  G G  HG       A  A  G
Sbjct: 384 AIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPG-GRLHGVHQHYQGAGTAVNG 439


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score =  144 bits (362), Expect = 1e-34
 Identities = 64/82 (78%), Positives = 76/82 (92%)

Query: 4   PVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKR 63
           P++ VKRPMNAFMVWS AQRR+MAQ+NPKMHNSEISKRLGA+WKLL E EKRPF++EAKR
Sbjct: 45  PLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKR 104

Query: 64  LRAMHMKEHPDYKYRPRRKPKT 85
           LRA H++++PDYKYRPRRK K+
Sbjct: 105 LRARHLRDYPDYKYRPRRKAKS 126


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score =  139 bits (350), Expect = 3e-33
 Identities = 90/239 (37%), Positives = 121/239 (50%), Gaps = 26/239 (10%)

Query: 4   PVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKR 63
           P  H+KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WKLL +S+K PFI EA+R
Sbjct: 55  PSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAER 114

Query: 64  LRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGG 123
           LR  HM ++PDYKYRPR+K K+       +       G   D       +G G H G GG
Sbjct: 115 LRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGD---KVGGSGGGGHGGGGG 171

Query: 124 GLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDL-----GSK 178
           G    S  A      A+   A ++    +S  +  A  A      P++ L L     G K
Sbjct: 172 G---GSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGK 228

Query: 179 MAEISSSSSGLPYASSLGYPTAGAGAFH---------------GAAAAAAAAAAAAGGH 222
            A  +++S     A +      GA A H                +AA+A+AA AA G H
Sbjct: 229 AAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKH 287



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 5/89 (5%)

Query: 99  GLGGVADAEHPALKAGAGLHAGAGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAA 158
           G+G  AD   P      GL+   G G  P++   +   +AA++ AA       +  A+  
Sbjct: 311 GVGAGADPSDPL-----GLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLR 365

Query: 159 AAAAAAAAGSPYSLLDLGSKMAEISSSSS 187
           AA+ A ++   ++     S  +  SSS S
Sbjct: 366 AASPAPSSAPSHASSSASSHSSSSSSSGS 394


>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score =  134 bits (337), Expect = 9e-32
 Identities = 73/161 (45%), Positives = 97/161 (60%), Gaps = 19/161 (11%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WK+L +SEK PFI EA+RLR 
Sbjct: 48  HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107

Query: 67  MHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV 126
            HM ++PDYKYRPR+KP    K D  A P        + ++ P   A  G    AGGG  
Sbjct: 108 KHMADYPDYKYRPRKKP----KMDPSAKP--------SASQSPEKSAAGGGGGSAGGG-- 153

Query: 127 PESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAG 167
                A   K +  ++    ++  P +A A A A  AA +G
Sbjct: 154 -----AGGAKTSKGSSKKCGKLKAPAAAGAKAGAGKAAQSG 189


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score =  125 bits (315), Expect = 3e-29
 Identities = 58/83 (69%), Positives = 71/83 (85%)

Query: 6   DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65
           D VKRPMNAF+VWSR QRRKMA ENP+M NSEISK+LG +WK+LTE+EK PF  EA++L+
Sbjct: 58  DRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQ 117

Query: 66  AMHMKEHPDYKYRPRRKPKTLLK 88
           AMH +++P+YKYRPRRK K L K
Sbjct: 118 AMHREKYPNYKYRPRRKAKMLPK 140


>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
          Length = 315

 Score =  125 bits (315), Expect = 3e-29
 Identities = 80/184 (43%), Positives = 97/184 (52%), Gaps = 25/184 (13%)

Query: 4   PVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKR 63
           P  H+KRPMNAFMVWS+ +RRK+  + P MHN+EISKRLG  W+LL +SEK PF+ EA+R
Sbjct: 36  PSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAER 95

Query: 64  LRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG--- 120
           LR  HM ++PDYKYRPR+K K    K +   P   G GG      P L    G  A    
Sbjct: 96  LRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGSG-GGSRLKPGPQLPGRGGRRAAGGP 154

Query: 121 -AGGGLVPES-------------LLANPEK-------AAAAAAAAAARVFFPQSAAAAAA 159
             GG   PE              L+  P +       A  AA   A R   P    AAAA
Sbjct: 155 LGGGAAAPEDDDEDDDEELLEVRLVETPGRELWRMVPAGRAARGQAERAQGPSGEGAAAA 214

Query: 160 AAAA 163
           AAA+
Sbjct: 215 AAAS 218


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score =  123 bits (309), Expect = 2e-28
 Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 20/251 (7%)

Query: 2   SKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEA 61
           SK   HVKRPMNAFMVW++A RRK+A + P +HN+E+SK LG  W+LL ES+KRPFI+EA
Sbjct: 98  SKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEA 157

Query: 62  KRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGA 121
           +RLR  H K+HPDYKY+PRR+      + +   P      G   A     K+    H   
Sbjct: 158 ERLRMQHKKDHPDYKYQPRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHP 217

Query: 122 GGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAA------AAAAAAGSP---YSL 172
           G G        NPE  +  +         P++   +  A       +    G P   +  
Sbjct: 218 GEGSPMSD--GNPEHPSGQSHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGKPHIDFGN 275

Query: 173 LDLGSKMAEISSSSSGL------PYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSH 226
           +D+G    E+ S+           Y    G+P     ++  A     +A A A GH+   
Sbjct: 276 VDIGEISHEVMSNMETFDVAELDQYLPPNGHP-GHVSSYSAAGYGLGSALAVASGHSAWI 334

Query: 227 PSPGNPGYMIP 237
             P  PG  +P
Sbjct: 335 SKP--PGVALP 343


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score =  122 bits (307), Expect = 3e-28
 Identities = 62/124 (50%), Positives = 78/124 (62%), Gaps = 19/124 (15%)

Query: 3   KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAK 62
           K   HVKRPMNAFMVW++A RRK+A + P +HN+E+SK LG  W+LL+ESEKRPF++EA+
Sbjct: 97  KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156

Query: 63  RLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAG 122
           RLR  H K+HPDYKY+PRR+                     A A H    +GA L    G
Sbjct: 157 RLRVQHKKDHPDYKYQPRRRKS-------------------AKAGHSDSDSGAELGPHPG 197

Query: 123 GGLV 126
           GG V
Sbjct: 198 GGAV 201


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score =  122 bits (305), Expect = 4e-28
 Identities = 53/81 (65%), Positives = 67/81 (82%)

Query: 2   SKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEA 61
           SK   HVKRPMNAFMVW++A RRK+A + P +HN+E+SK LG  W+LL ESEKRPF++EA
Sbjct: 99  SKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEA 158

Query: 62  KRLRAMHMKEHPDYKYRPRRK 82
           +RLR  H K+HPDYKY+PRR+
Sbjct: 159 ERLRVQHKKDHPDYKYQPRRR 179


>gi|11967991 SRY-box 17 [Homo sapiens]
          Length = 414

 Score =  120 bits (302), Expect = 1e-27
 Identities = 60/125 (48%), Positives = 87/125 (69%), Gaps = 6/125 (4%)

Query: 2   SKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEA 61
           +K    ++RPMNAFMVW++ +R+++AQ+NP +HN+E+SK LG  WK LT +EKRPF++EA
Sbjct: 62  AKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEA 121

Query: 62  KRLRAMHMKEHPDYKYRPRRKPKT-LLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG 120
           +RLR  HM++HP+YKYRPRR+ +   LK+ +  F     L G+A+ +  AL    G  A 
Sbjct: 122 ERLRVQHMQDHPNYKYRPRRRKQVKRLKRVEGGF-----LHGLAEPQAAALGPEGGRVAM 176

Query: 121 AGGGL 125
            G GL
Sbjct: 177 DGLGL 181


>gi|8924248 SRY-box 18 [Homo sapiens]
          Length = 384

 Score =  113 bits (282), Expect = 2e-25
 Identities = 77/212 (36%), Positives = 112/212 (52%), Gaps = 26/212 (12%)

Query: 8   VKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAM 67
           ++RPMNAFMVW++ +R+++AQ+NP +HN+ +SK LG  WK L  +EKRPF++EA+RLR  
Sbjct: 85  IRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQ 144

Query: 68  HMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYG--LGGVADAEHP--ALKAGAGLHAGAGG 123
           H+++HP+YKYRPRRK     K+ + A  +  G  L G+A  + P     A +G  A A  
Sbjct: 145 HLRDHPNYKYRPRRK-----KQARKARRLEPGLLLPGLAPPQPPPEPFPAASG-SARAFR 198

Query: 124 GLVPESL------LANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDL-- 175
            L P         L  PE++           FFP  AA    A     A  PY+  +L  
Sbjct: 199 ELPPLGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAPEDCALRPFRA--PYAPTELSR 256

Query: 176 ------GSKMAEISSSSSGLPYASSLGYPTAG 201
                 G+ +AE   ++      + L Y T G
Sbjct: 257 DPGGCYGAPLAEALRTAPPAAPLAGLYYGTLG 288


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score =  112 bits (280), Expect = 4e-25
 Identities = 45/75 (60%), Positives = 65/75 (86%)

Query: 8   VKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAM 67
           ++RPMNAFMVW++ +R+++A +NP +HN+E+SK LG  WK LT S+KRP++DEA+RLR  
Sbjct: 45  IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQ 104

Query: 68  HMKEHPDYKYRPRRK 82
           HM+++P+YKYRPRRK
Sbjct: 105 HMQDYPNYKYRPRRK 119


>gi|41406089 SRY-box 13 [Homo sapiens]
          Length = 622

 Score =  103 bits (256), Expect = 2e-22
 Identities = 44/81 (54%), Positives = 60/81 (74%)

Query: 2   SKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEA 61
           S+   H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +T  EK+P+ +E 
Sbjct: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477

Query: 62  KRLRAMHMKEHPDYKYRPRRK 82
            RL   H++++PDYKY+PR K
Sbjct: 478 ARLSRQHLEKYPDYKYKPRPK 498


>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
           sapiens]
          Length = 377

 Score =  102 bits (255), Expect = 3e-22
 Identities = 45/85 (52%), Positives = 61/85 (71%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +T  EK+P+ +E  RL  
Sbjct: 169 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 228

Query: 67  MHMKEHPDYKYRPRRKPKTLLKKDK 91
            H++++PDYKY+PR K   L+   K
Sbjct: 229 QHLEKYPDYKYKPRPKRTCLVDGKK 253


>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
           sapiens]
          Length = 750

 Score =  102 bits (255), Expect = 3e-22
 Identities = 45/85 (52%), Positives = 61/85 (71%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +T  EK+P+ +E  RL  
Sbjct: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601

Query: 67  MHMKEHPDYKYRPRRKPKTLLKKDK 91
            H++++PDYKY+PR K   L+   K
Sbjct: 602 QHLEKYPDYKYKPRPKRTCLVDGKK 626


>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
           sapiens]
          Length = 763

 Score =  102 bits (255), Expect = 3e-22
 Identities = 45/85 (52%), Positives = 61/85 (71%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +T  EK+P+ +E  RL  
Sbjct: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614

Query: 67  MHMKEHPDYKYRPRRKPKTLLKKDK 91
            H++++PDYKY+PR K   L+   K
Sbjct: 615 QHLEKYPDYKYKPRPKRTCLVDGKK 639


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 41/76 (53%), Positives = 59/76 (77%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+P+ +E  RL  
Sbjct: 633 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 692

Query: 67  MHMKEHPDYKYRPRRK 82
           +H++++P+YKY+PR K
Sbjct: 693 IHLEKYPNYKYKPRPK 708


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 41/76 (53%), Positives = 59/76 (77%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+P+ +E  RL  
Sbjct: 593 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 652

Query: 67  MHMKEHPDYKYRPRRK 82
           +H++++P+YKY+PR K
Sbjct: 653 IHLEKYPNYKYKPRPK 668


>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 41/76 (53%), Positives = 59/76 (77%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+P+ +E  RL  
Sbjct: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655

Query: 67  MHMKEHPDYKYRPRRK 82
           +H++++P+YKY+PR K
Sbjct: 656 IHLEKYPNYKYKPRPK 671


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score = 99.4 bits (246), Expect = 3e-21
 Identities = 41/76 (53%), Positives = 59/76 (77%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           H+KRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+P+ +E  RL  
Sbjct: 600 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 659

Query: 67  MHMKEHPDYKYRPRRK 82
           +H++++P+YKY+PR K
Sbjct: 660 IHLEKYPNYKYKPRPK 675


>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 38/74 (51%), Positives = 55/74 (74%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           HVKRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  L+E +K+P+ DEA++++ 
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395

Query: 67  MHMKEHPDYKYRPR 80
            H +E P + Y+PR
Sbjct: 396 KHREEFPGWVYQPR 409


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 38/74 (51%), Positives = 55/74 (74%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           HVKRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  L+E +K+P+ DEA++++ 
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395

Query: 67  MHMKEHPDYKYRPR 80
            H +E P + Y+PR
Sbjct: 396 KHREEFPGWVYQPR 409


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 79.3 bits (194), Expect = 3e-15
 Identities = 66/225 (29%), Positives = 102/225 (45%), Gaps = 17/225 (7%)

Query: 6   DHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLR 65
           DH++RPMNAFM++S+  R  + Q +P   N  +SK LG  W  L   EK+ + D A +++
Sbjct: 198 DHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVK 257

Query: 66  AMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGG--VADAEHPALKAGAGLHAGAGG 123
             H K HPD+K+  + + K+       A P   GL G      E    + G     G   
Sbjct: 258 EAHFKAHPDWKWCNKDRKKS----SSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSS 313

Query: 124 GLV---PESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLG---- 176
            L+    ++LL++  KA  +++  A R+    +     +A   A + S    LD G    
Sbjct: 314 ELLSVAAQTLLSSDTKAPGSSSCGAERL---HTVGGPGSARPRAFSHSGVHSLDGGEVDS 370

Query: 177 SKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGG 221
             + E++   SG P + S   P+   GA    AA     A AA G
Sbjct: 371 QALQELTQMVSG-PASYSGPKPSTQYGAPGPFAAPGEGGALAATG 414


>gi|24497554 homeobox A13 [Homo sapiens]
          Length = 388

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 60/146 (41%), Positives = 73/146 (50%), Gaps = 23/146 (15%)

Query: 122 GGGLVPESLLANPE-KAAAAAAAAAARVF------FPQSAAAA-------AAAAAAAAAG 167
           GGGLV + L  N E  AAAAAAAAAA         FP  AAAA       AAAAAAAAA 
Sbjct: 23  GGGLVADELNKNMEGAAAAAAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAA 82

Query: 168 SPYSLLDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHP 227
           +     +L +  A ++  ++   Y+S+ G     A A   AAAAAAAAAAAA   +   P
Sbjct: 83  AANQCRNLMAHPAPLAPGAAS-AYSSAPGEAPPSAAA--AAAAAAAAAAAAAAASSSGGP 139

Query: 228 SPGNPG------YMIPCNCSAWPSPG 247
            P  P          PC+ +A  S G
Sbjct: 140 GPAGPAGAEAAKQCSPCSAAAQSSSG 165



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 59/164 (35%), Positives = 64/164 (39%), Gaps = 54/164 (32%)

Query: 110 ALKAGAGLHAGAGGGLVPESLLA----NPEKAAAAAAAAAARV------------FFPQS 153
           A  A A   AGAGGG  P    A    N   AAAAAAAAAA                P +
Sbjct: 42  AAAAAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGA 101

Query: 154 AAA------------AAAAAAAAAA----------GSPYSLLDLG----------SKMAE 181
           A+A            AAAAAAAAAA          G P      G          S  A+
Sbjct: 102 ASAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAAQ 161

Query: 182 ISSSSSGLPYA--SSLGYPTAGAG----AFHGAAAAAAAAAAAA 219
            SS  + LPY    S  YP A  G    A    A  A+AAAAAA
Sbjct: 162 SSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAAA 205


>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
          Length = 588

 Score = 61.2 bits (147), Expect = 9e-10
 Identities = 53/221 (23%), Positives = 92/221 (41%), Gaps = 26/221 (11%)

Query: 7   HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
           HVK+P+NAFM++ +  R K+  E     ++ I++ LG +W  L+  E+  + + A++ R 
Sbjct: 345 HVKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQ 404

Query: 67  MHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAGAGGGLV 126
           +H + +P +  R     K   K++K              ++    +A   L   A     
Sbjct: 405 LHSQLYPTWSARDNYGKKKKRKREKQL--------SQTQSQQQVQEAEGAL---ASKSKK 453

Query: 127 PESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSS 186
           P      PEK   + A++   +    +  +AA A+ AA A +                S 
Sbjct: 454 PCVQYLPPEKPCDSPASSHGSMLDSPATPSAALASPAAPAAT---------------HSE 498

Query: 187 SGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHP 227
              P + +    T    A H AA  +A AAA++ G   S P
Sbjct: 499 QAQPLSLTTKPETRAQLALHSAAFLSAKAAASSSGQMGSQP 539


>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
           sapiens]
          Length = 941

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 7/99 (7%)

Query: 4   PVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKR 63
           P    +RPMNAF+++ +  R  + QE+P++ N   +K L   W +L   EK+ + D AK 
Sbjct: 76  PEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKE 135

Query: 64  LRAMHMKEHPDYKYRPRRK-------PKTLLKKDKFAFP 95
            +   MK +P YK+ P          P    +K  +AFP
Sbjct: 136 YKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFP 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.128    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,312,248
Number of Sequences: 37866
Number of extensions: 688949
Number of successful extensions: 12341
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 352
Number of HSP's successfully gapped in prelim test: 321
Number of HSP's that attempted gapping in prelim test: 5914
Number of HSP's gapped (non-prelim): 2886
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.