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Search of human proteins with 56243522
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56243522 syntenin isoform 1 [Homo sapiens]
(298 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749490 syntenin isoform 1 [Homo sapiens] 585 e-167
gi|56243522 syntenin isoform 1 [Homo sapiens] 585 e-167
gi|55749523 syntenin isoform 3 [Homo sapiens] 578 e-165
gi|55749515 syntenin isoform 3 [Homo sapiens] 578 e-165
gi|55749504 syntenin isoform 2 [Homo sapiens] 568 e-162
gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens] 343 1e-94
gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens] 298 3e-81
gi|22035548 amyloid beta A4 precursor protein-binding, family A,... 62 5e-10
gi|194353992 amyloid beta A4 precursor protein-binding, family A... 61 1e-09
gi|22035550 amyloid beta A4 precursor protein-binding, family A,... 61 1e-09
gi|11342678 amyloid beta (A4) precursor protein-binding, family ... 57 2e-08
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 49 7e-06
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 49 7e-06
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 47 2e-05
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 47 2e-05
gi|45827729 scribble isoform b [Homo sapiens] 45 1e-04
gi|45827731 scribble isoform a [Homo sapiens] 45 1e-04
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 44 1e-04
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 44 1e-04
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 44 1e-04
gi|11993943 Tax1 binding protein 3 [Homo sapiens] 44 2e-04
gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo... 43 3e-04
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 43 4e-04
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 43 4e-04
gi|21361142 PDZ domain containing 1 [Homo sapiens] 43 4e-04
gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchan... 42 5e-04
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 42 5e-04
gi|9507163 syntrophin, gamma 1 [Homo sapiens] 42 5e-04
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens] 42 5e-04
gi|95089461 discs large homolog 5 [Homo sapiens] 42 9e-04
>gi|55749490 syntenin isoform 1 [Homo sapiens]
Length = 298
Score = 585 bits (1508), Expect = e-167
Identities = 298/298 (100%), Positives = 298/298 (100%)
Query: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
Query: 61 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120
LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120
Query: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180
QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180
Query: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240
AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240
Query: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298
INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298
>gi|56243522 syntenin isoform 1 [Homo sapiens]
Length = 298
Score = 585 bits (1508), Expect = e-167
Identities = 298/298 (100%), Positives = 298/298 (100%)
Query: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
Query: 61 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120
LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120
Query: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180
QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180
Query: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240
AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240
Query: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298
INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298
>gi|55749523 syntenin isoform 3 [Homo sapiens]
Length = 297
Score = 578 bits (1491), Expect = e-165
Identities = 297/298 (99%), Positives = 297/298 (99%), Gaps = 1/298 (0%)
Query: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
Query: 61 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120
LNEEEIRANVAVVSGAPLQG LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61 LNEEEIRANVAVVSGAPLQG-LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 119
Query: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180
QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 120 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 179
Query: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240
AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 180 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 239
Query: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298
INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 240 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 297
>gi|55749515 syntenin isoform 3 [Homo sapiens]
Length = 297
Score = 578 bits (1491), Expect = e-165
Identities = 297/298 (99%), Positives = 297/298 (99%), Gaps = 1/298 (0%)
Query: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
Query: 61 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120
LNEEEIRANVAVVSGAPLQG LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61 LNEEEIRANVAVVSGAPLQG-LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 119
Query: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180
QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 120 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 179
Query: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240
AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 180 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 239
Query: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298
INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 240 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 297
>gi|55749504 syntenin isoform 2 [Homo sapiens]
Length = 292
Score = 568 bits (1463), Expect = e-162
Identities = 292/298 (97%), Positives = 292/298 (97%), Gaps = 6/298 (2%)
Query: 1 MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60
MSLYPSLEDLK AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1 MSLYPSLEDLK------AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 54
Query: 61 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120
LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 55 LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 114
Query: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180
QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 115 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 174
Query: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240
AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 175 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 234
Query: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298
INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 235 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 292
>gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens]
Length = 292
Score = 343 bits (880), Expect = 1e-94
Identities = 174/296 (58%), Positives = 228/296 (77%), Gaps = 7/296 (2%)
Query: 2 SLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSL 61
SLYPSLEDLKVD+ IQAQ A+P PA+ +A+A P LYP L EL YMGLSL
Sbjct: 3 SLYPSLEDLKVDQAIQAQVR--ASPKMPALPVQATAISPPPV-LYPNL-AELENYMGLSL 58
Query: 62 NEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQ 121
+ +E++ ++ + V+ P MVAPVTG +G+RRAEIK G+RE+ LCKD+
Sbjct: 59 SSQEVQESLLQIPEG--DSTAVSGPGP-GQMVAPVTGYSLGVRRAEIKPGVREIHLCKDE 115
Query: 122 DGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQA 181
GK GLRL+ +D G+FVQLVQAN+PASLVGLRFGDQ+LQI+G +CAGWSS KAH+V+K+A
Sbjct: 116 RGKTGLRLRKVDQGLFVQLVQANTPASLVGLRFGDQLLQIDGRDCAGWSSHKAHQVVKKA 175
Query: 182 FGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEI 241
G+KI + +RDRPF+RT+TMHKDS GHVGF+ K GKI S+VK SSAARNGLLT H +CE+
Sbjct: 176 SGDKIVVVVRDRPFQRTVTMHKDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEV 235
Query: 242 NGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPE 297
+GQNVIGLKD +I +IL+T+G VVT+TI+P+ I+EH++K++ P ++ MDH+IP+
Sbjct: 236 DGQNVIGLKDKKIMEILATAGNVVTLTIIPSVIYEHMVKKLPPVLLHHTMDHSIPD 291
>gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens]
Length = 207
Score = 298 bits (764), Expect = 3e-81
Identities = 136/206 (66%), Positives = 177/206 (85%)
Query: 92 MVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVG 151
MVAPVTG +G+RRAEIK G+RE+ LCKD+ GK GLRL+ +D G+FVQLVQAN+PASLVG
Sbjct: 1 MVAPVTGYSLGVRRAEIKPGVREIHLCKDERGKTGLRLRKVDQGLFVQLVQANTPASLVG 60
Query: 152 LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVGF 211
LRFGDQ+LQI+G +CAGWSS KAH+V+K+A G+KI + +RDRPF+RT+TMHKDS GHVGF
Sbjct: 61 LRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVVVVRDRPFQRTVTMHKDSMGHVGF 120
Query: 212 IFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMP 271
+ K GKI S+VK SSAARNGLLT H +CE++GQNVIGLKD +I +IL+T+G VVT+TI+P
Sbjct: 121 VIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAGNVVTLTIIP 180
Query: 272 AFIFEHIIKRMAPSIMKSLMDHTIPE 297
+ I+EH++K++ P ++ MDH+IP+
Sbjct: 181 SVIYEHMVKKLPPVLLHHTMDHSIPD 206
>gi|22035548 amyloid beta A4 precursor protein-binding, family A,
member 1 [Homo sapiens]
Length = 837
Score = 62.4 bits (150), Expect = 5e-10
Identities = 41/152 (26%), Positives = 70/152 (46%), Gaps = 3/152 (1%)
Query: 136 IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTI-RD 192
+ + + PA G L GDQ++ ING + G ++K + ++ + I R
Sbjct: 683 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRC 742
Query: 193 RPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDS 252
P + D +GF +NG I S+++ A R G+ H I EINGQ+V+
Sbjct: 743 PPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHE 802
Query: 253 QIADILSTSGTVVTITIMPAFIFEHIIKRMAP 284
+I ILS + + + MPA ++ + + P
Sbjct: 803 KIVHILSNAVGEIHMKTMPAAMYRLLTAQEQP 834
>gi|194353992 amyloid beta A4 precursor protein-binding, family A,
member 2 isoform b [Homo sapiens]
Length = 737
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 146 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 203
PA+ G L GDQ++ ING + G ++K + ++ + I P T+ + +
Sbjct: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
Query: 204 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 262
D +GF +NG I S+++ A R G+ H I EINGQ+V+ +I LS S
Sbjct: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
Query: 263 TVVTITIMPAFIFEHIIKRMAP 284
+ + MPA +F + + P
Sbjct: 713 GEIHMKTMPAAMFRLLTGQETP 734
>gi|22035550 amyloid beta A4 precursor protein-binding, family A,
member 2 isoform a [Homo sapiens]
Length = 749
Score = 60.8 bits (146), Expect = 1e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 146 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 203
PA+ G L GDQ++ ING + G ++K + ++ + I P T+ + +
Sbjct: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
Query: 204 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 262
D +GF +NG I S+++ A R G+ H I EINGQ+V+ +I LS S
Sbjct: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
Query: 263 TVVTITIMPAFIFEHIIKRMAP 284
+ + MPA +F + + P
Sbjct: 725 GEIHMKTMPAAMFRLLTGQETP 746
>gi|11342678 amyloid beta (A4) precursor protein-binding, family A,
member 3 [Homo sapiens]
Length = 575
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 8/180 (4%)
Query: 113 REVILCKDQDGKIGLRLKS------IDNGIFVQLVQANSPASLVGLRFGDQVLQINGENC 166
REV L K + +G+ L + + L+ L GD++ ING +
Sbjct: 393 REVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSL 452
Query: 167 AGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHKD-STGHVGFIFKNGKITSIVKD 224
G +++ + +T++I P T +H+ + +GF ++G I S+++
Sbjct: 453 VGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRG 512
Query: 225 SSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAP 284
A R G+ H I EINGQ+V+ ++I ++L+ + V I MPA + + + P
Sbjct: 513 GIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQP 572
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 48.5 bits (114), Expect = 7e-06
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 11/127 (8%)
Query: 73 VSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSI 132
VS + GQ A P+ + + V G+D EI + R+V+L + G +G +
Sbjct: 431 VSPSSFLGQTPASPARYSPVSKAVLGDD------EITREPRKVVLHRGSTG-LGFNIVGG 483
Query: 133 DNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMT 189
++G IF+ + A PA L G LR GD+++ +N + S ++A LK A G+ +T+
Sbjct: 484 EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNA-GQAVTIV 542
Query: 190 IRDRPFE 196
+ RP E
Sbjct: 543 AQYRPEE 549
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 48.5 bits (114), Expect = 7e-06
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 11/127 (8%)
Query: 73 VSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSI 132
VS + GQ A P+ + + V G+D EI + R+V+L + G +G +
Sbjct: 431 VSPSSFLGQTPASPARYSPVSKAVLGDD------EITREPRKVVLHRGSTG-LGFNIVGG 483
Query: 133 DNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMT 189
++G IF+ + A PA L G LR GD+++ +N + S ++A LK A G+ +T+
Sbjct: 484 EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNA-GQAVTIV 542
Query: 190 IRDRPFE 196
+ RP E
Sbjct: 543 AQYRPEE 549
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 5/87 (5%)
Query: 113 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 169
R++IL K G +G + ++G IFV + A PA L G LR GD++L +NG N
Sbjct: 48 RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 106
Query: 170 SSDKAHKVLKQAFGEKITMTIRDRPFE 196
+ ++A LK+A G+ +T+ + RP E
Sbjct: 107 THEQAAAALKRA-GQSVTIVAQYRPEE 132
Score = 28.5 bits (62), Expect = 7.5
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 8/78 (10%)
Query: 197 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 249
R I +HK STG +GF G+ ++ I+ A +G L + I +NG N+
Sbjct: 48 RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 106
Query: 250 KDSQIADILSTSGTVVTI 267
Q A L +G VTI
Sbjct: 107 THEQAAAALKRAGQSVTI 124
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 5/87 (5%)
Query: 113 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 169
R++IL K G +G + ++G IFV + A PA L G LR GD++L +NG N
Sbjct: 385 RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 443
Query: 170 SSDKAHKVLKQAFGEKITMTIRDRPFE 196
+ ++A LK+A G+ +T+ + RP E
Sbjct: 444 THEQAAAALKRA-GQSVTIVAQYRPEE 469
Score = 28.5 bits (62), Expect = 7.5
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 8/78 (10%)
Query: 197 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 249
R I +HK STG +GF G+ ++ I+ A +G L + I +NG N+
Sbjct: 385 RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 443
Query: 250 KDSQIADILSTSGTVVTI 267
Q A L +G VTI
Sbjct: 444 THEQAAAALKRAGQSVTI 461
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 44.7 bits (104), Expect = 1e-04
Identities = 36/158 (22%), Positives = 67/158 (42%), Gaps = 19/158 (12%)
Query: 135 GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRD-- 192
G+F+ V A+ GLR GD++L +NG++ + +A L + E + RD
Sbjct: 1035 GVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVRRDPA 1094
Query: 193 RPFERTITMHKDSTGHVGFIFKNGK----------------ITSIVKDSSAARNG-LLTE 235
P R + + K +G + G I+ + +A R+G L
Sbjct: 1095 PPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRDGRLRVG 1154
Query: 236 HNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAF 273
+ E+N Q+++GL + +L + G +T+ + F
Sbjct: 1155 LRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGF 1192
Score = 41.6 bits (96), Expect = 9e-04
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 123 GKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAF 182
GK K D GIF+ V PA+ G+R GD++L++NG G +A + L+ A
Sbjct: 745 GKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGA- 803
Query: 183 GEKITMTI-RDRPFE 196
G + M + R+R E
Sbjct: 804 GTAVQMRVWRERMVE 818
Score = 29.3 bits (64), Expect = 4.4
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 123 GKIGLRLKSIDNGIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQA 181
GK ++ D GIFV + A G L+ GD+VL ING + D A +L A
Sbjct: 879 GKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAA 938
Score = 28.9 bits (63), Expect = 5.7
Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 14/87 (16%)
Query: 196 ERTITMHKDSTGHVGFIFKNGK-------------ITSIVKDSSAARNGLLTEHNICEIN 242
E T+T+ + TG +G GK I+ + ++ AAR G+ + E+N
Sbjct: 726 ELTLTILRQ-TGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVN 784
Query: 243 GQNVIGLKDSQIADILSTSGTVVTITI 269
G + G + + + L +GT V + +
Sbjct: 785 GVALQGAEHHEAVEALRGAGTAVQMRV 811
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 44.7 bits (104), Expect = 1e-04
Identities = 36/158 (22%), Positives = 67/158 (42%), Gaps = 19/158 (12%)
Query: 135 GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRD-- 192
G+F+ V A+ GLR GD++L +NG++ + +A L + E + RD
Sbjct: 1035 GVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVRRDPA 1094
Query: 193 RPFERTITMHKDSTGHVGFIFKNGK----------------ITSIVKDSSAARNG-LLTE 235
P R + + K +G + G I+ + +A R+G L
Sbjct: 1095 PPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRDGRLRVG 1154
Query: 236 HNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAF 273
+ E+N Q+++GL + +L + G +T+ + F
Sbjct: 1155 LRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGF 1192
Score = 41.6 bits (96), Expect = 9e-04
Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 123 GKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAF 182
GK K D GIF+ V PA+ G+R GD++L++NG G +A + L+ A
Sbjct: 745 GKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGA- 803
Query: 183 GEKITMTI-RDRPFE 196
G + M + R+R E
Sbjct: 804 GTAVQMRVWRERMVE 818
Score = 29.3 bits (64), Expect = 4.4
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 123 GKIGLRLKSIDNGIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQA 181
GK ++ D GIFV + A G L+ GD+VL ING + D A +L A
Sbjct: 879 GKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAA 938
Score = 28.9 bits (63), Expect = 5.7
Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 14/87 (16%)
Query: 196 ERTITMHKDSTGHVGFIFKNGK-------------ITSIVKDSSAARNGLLTEHNICEIN 242
E T+T+ + TG +G GK I+ + ++ AAR G+ + E+N
Sbjct: 726 ELTLTILRQ-TGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVN 784
Query: 243 GQNVIGLKDSQIADILSTSGTVVTITI 269
G + G + + + L +GT V + +
Sbjct: 785 GVALQGAEHHEAVEALRGAGTAVQMRV 811
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 5/85 (5%)
Query: 113 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 169
R+V+L K G +G + ++G IFV + A PA L G L+ GDQ+L +NG + G
Sbjct: 317 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 375
Query: 170 SSDKAHKVLKQAFGEKITMTIRDRP 194
S ++A LK A G+ +T+ + +P
Sbjct: 376 SHEQAAAALKGA-GQTVTIIAQYQP 399
Score = 29.3 bits (64), Expect = 4.4
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 8/78 (10%)
Query: 197 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 249
R + +HK STG +GF G+ ++ I+ A +G L + I +NG ++ G
Sbjct: 317 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 375
Query: 250 KDSQIADILSTSGTVVTI 267
Q A L +G VTI
Sbjct: 376 SHEQAAAALKGAGQTVTI 393
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 5/85 (5%)
Query: 113 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 169
R+V+L K G +G + ++G IFV + A PA L G L+ GDQ+L +NG + G
Sbjct: 525 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 583
Query: 170 SSDKAHKVLKQAFGEKITMTIRDRP 194
S ++A LK A G+ +T+ + +P
Sbjct: 584 SHEQAAAALKGA-GQTVTIIAQYQP 607
Score = 29.3 bits (64), Expect = 4.4
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 8/78 (10%)
Query: 197 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 249
R + +HK STG +GF G+ ++ I+ A +G L + I +NG ++ G
Sbjct: 525 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 583
Query: 250 KDSQIADILSTSGTVVTI 267
Q A L +G VTI
Sbjct: 584 SHEQAAAALKGAGQTVTI 601
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 5/85 (5%)
Query: 113 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 169
R+V+L K G +G + ++G IFV + A PA L G L+ GDQ+L +NG + G
Sbjct: 420 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 478
Query: 170 SSDKAHKVLKQAFGEKITMTIRDRP 194
S ++A LK A G+ +T+ + +P
Sbjct: 479 SHEQAAAALKGA-GQTVTIIAQYQP 502
Score = 29.3 bits (64), Expect = 4.4
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 8/78 (10%)
Query: 197 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 249
R + +HK STG +GF G+ ++ I+ A +G L + I +NG ++ G
Sbjct: 420 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 478
Query: 250 KDSQIADILSTSGTVVTI 267
Q A L +G VTI
Sbjct: 479 SHEQAAAALKGAGQTVTI 496
>gi|11993943 Tax1 binding protein 3 [Homo sapiens]
Length = 124
Score = 43.5 bits (101), Expect = 2e-04
Identities = 19/67 (28%), Positives = 37/67 (55%)
Query: 133 DNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRD 192
D GI+V V PA + GL+ GD+++Q+NG + + D+A K L + E + + +
Sbjct: 52 DKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTR 111
Query: 193 RPFERTI 199
+ ++ +
Sbjct: 112 QSLQKAV 118
>gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo
sapiens]
Length = 1544
Score = 43.1 bits (100), Expect = 3e-04
Identities = 24/90 (26%), Positives = 49/90 (54%), Gaps = 3/90 (3%)
Query: 105 RAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGE 164
R+EI ++ ++ + D GL + DN +FVQ V+ + A G++ GD+++++NG
Sbjct: 62 RSEIYGLVQRCVIIQKDDNGFGLTVSG-DNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT 120
Query: 165 NCAGWSSDKAHKVLKQAFGEKITMTIRDRP 194
+ + K++K G + +T++ RP
Sbjct: 121 LVTHSNHLEVVKLIKS--GSYVALTVQGRP 148
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 42.7 bits (99), Expect = 4e-04
Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 135 GIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDR 193
GIF+ + A PA L G LR GDQ+L +NG + S ++A LK A G+ +T+ + +
Sbjct: 378 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA-GQTVTIIAQYK 436
Query: 194 PFE 196
P E
Sbjct: 437 PEE 439
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 42.7 bits (99), Expect = 4e-04
Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 135 GIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDR 193
GIF+ + A PA L G LR GDQ+L +NG + S ++A LK A G+ +T+ + +
Sbjct: 332 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA-GQTVTIIAQYK 390
Query: 194 PFE 196
P E
Sbjct: 391 PEE 393
>gi|21361142 PDZ domain containing 1 [Homo sapiens]
Length = 519
Score = 42.7 bits (99), Expect = 4e-04
Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 49/206 (23%)
Query: 113 REVILCKDQDGKIG--LRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWS 170
RE L K + G LR++ G V++V+ SPA GL+ GD+VL+ING
Sbjct: 8 RECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEE 67
Query: 171 SDKAHKVLKQAFGEKITMTIRD-RPFERTITMHKD------------------------- 204
+ +++++ G +T+ + D +E+ + D
Sbjct: 68 HMQVVDLVRKS-GNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILSPVMNGG 126
Query: 205 --------------STGHVGFIFK--NGK----ITSIVKDSSAARNGLLTEHNICEINGQ 244
G GF K GK +T I A R G+L + ++ E+NG+
Sbjct: 127 VQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGE 186
Query: 245 NVIGLKDSQIADILSTSGTVVTITIM 270
NV ++ + + SG+ V ++
Sbjct: 187 NVEDASHEEVVEKVKKSGSRVMFLLV 212
Score = 39.3 bits (90), Expect = 0.004
Identities = 35/182 (19%), Positives = 73/182 (40%), Gaps = 34/182 (18%)
Query: 121 QDGKIGLRLKSIDN--GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVL 178
+ G G LK++ G+++ + A G+ D ++++NGEN S ++ + +
Sbjct: 141 EGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKV 200
Query: 179 KQAFGEKITMTIRDRPFE------------------------RTITMHKDSTGHVGFIFK 214
K++ G ++ + D+ + R + M K S G+ GF +
Sbjct: 201 KKS-GSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGY-GFYLR 258
Query: 215 NGK------ITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTIT 268
G I I S A GL + +NG++V L + +++ G ++
Sbjct: 259 AGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKGGDQTSLL 318
Query: 269 IM 270
++
Sbjct: 319 VV 320
Score = 35.8 bits (81), Expect = 0.047
Identities = 45/222 (20%), Positives = 82/222 (36%), Gaps = 58/222 (26%)
Query: 127 LRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKI 186
LR S G ++ + + SPA GL+ D V+ +NGE+ D +++++ G++
Sbjct: 257 LRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKG-GDQT 315
Query: 187 TMTIRDR----------------------------------PFERTITMHKDST------ 206
++ + D+ P ++ D+T
Sbjct: 316 SLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEVDHK 375
Query: 207 --------GHVGFIFKNGKI--------TSIVKDSSAARNGLLTEHNICEINGQNVIGLK 250
G G+ F I + K A GL E I E+NG NV+
Sbjct: 376 PKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEP 435
Query: 251 DSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMD 292
++ D + +SG VT+ + +++ + P I+ SL D
Sbjct: 436 YEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIP-IVSSLAD 476
Score = 34.3 bits (77), Expect = 0.14
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 4/76 (5%)
Query: 117 LCKDQDGKIGLRLKSIDN--GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKA 174
L K ++G G L +I G F++ VQ PA L GL D ++++NG N +K
Sbjct: 381 LAKGENG-YGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKV 439
Query: 175 HKVLKQAFGEKITMTI 190
+ Q+ G+ +T+ +
Sbjct: 440 VDRI-QSSGKNVTLLV 454
Score = 33.9 bits (76), Expect = 0.18
Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 199 ITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADIL 258
+ + KD+ GH+ + + K S A + GL + ING V + Q+ D++
Sbjct: 24 LRIEKDTEGHL--------VRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLV 75
Query: 259 STSGTVVTITIMPAFIFEHIIK 280
SG VT+ ++ +E +K
Sbjct: 76 RKSGNSVTLLVLDGDSYEKAVK 97
>gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchange
factor 2, partial [Homo sapiens]
Length = 803
Score = 42.4 bits (98), Expect = 5e-04
Identities = 23/66 (34%), Positives = 36/66 (54%)
Query: 135 GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRP 194
GIFV V + S A+ GL+ GDQ+L++NG+N KA ++L+ IT+
Sbjct: 410 GIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFV 469
Query: 195 FERTIT 200
F+ +T
Sbjct: 470 FKELLT 475
Score = 32.7 bits (73), Expect = 0.40
Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 218 ITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMP-AFIFE 276
+ S+ S A GL I E+NGQN ++ S+ +IL + T ++IT+ F+F+
Sbjct: 413 VDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEIL-RNNTHLSITVKTNLFVFK 471
Query: 277 HIIKRMA 283
++ R++
Sbjct: 472 ELLTRLS 478
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 42.4 bits (98), Expect = 5e-04
Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 7/89 (7%)
Query: 112 IREVILCKDQDGKIGLRLKSIDN------GIFVQLVQANSPASLVG-LRFGDQVLQINGE 164
I ++L K Q +G + + GI+V+ + A A+ G L+ GD++L++NGE
Sbjct: 214 ISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELNGE 273
Query: 165 NCAGWSSDKAHKVLKQAFGEKITMTIRDR 193
+ AG + A + KQA +T+T+R R
Sbjct: 274 SMAGLTHQDALQKFKQAKKGLLTLTVRTR 302
Score = 32.3 bits (72), Expect = 0.52
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 7/83 (8%)
Query: 106 AEIKQ--GIREVILCKDQDGKIGLRLKS---IDNGIF-VQLVQANSPASLVG-LRFGDQV 158
A +KQ GI IL K++ +G L ++N + V V N AS G ++ G++V
Sbjct: 1103 ATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEV 1162
Query: 159 LQINGENCAGWSSDKAHKVLKQA 181
L ING++ G + A +L+QA
Sbjct: 1163 LSINGKSLKGTTHHDALAILRQA 1185
>gi|9507163 syntrophin, gamma 1 [Homo sapiens]
Length = 517
Score = 42.4 bits (98), Expect = 5e-04
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 16/107 (14%)
Query: 184 EKITMTIRDRPF---ERTITMHKDSTGHVGFIFKNGK-------ITSIVKDSSAARNGLL 233
E+ + + PF ERT+T+ + + G G K G ++ I K+ A +GLL
Sbjct: 40 EQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLL 99
Query: 234 TEHN-ICEINGQNVIGLKDSQIADILSTSGTVVTITI-----MPAFI 274
+ I +ING NV + ++ +L +G VT+T+ PAF+
Sbjct: 100 FIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFL 146
Score = 37.4 bits (85), Expect = 0.016
Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 111 GIREVILCKDQDGKIGLRLKS---IDNGIFVQLVQANSPASLVGLRF-GDQVLQINGENC 166
G R V + + G GL +K + + V + A L GL F GD +LQING N
Sbjct: 54 GERTVTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINV 113
Query: 167 AGWSSDKAHKVLKQAFGEKITMTI 190
++ +VL+ A GE++T+T+
Sbjct: 114 RKCRHEEVVQVLRNA-GEEVTLTV 136
>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
Length = 1499
Score = 42.4 bits (98), Expect = 5e-04
Identities = 23/66 (34%), Positives = 36/66 (54%)
Query: 135 GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRP 194
GIFV V + S A+ GL+ GDQ+L++NG+N KA ++L+ IT+
Sbjct: 410 GIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFV 469
Query: 195 FERTIT 200
F+ +T
Sbjct: 470 FKELLT 475
Score = 32.7 bits (73), Expect = 0.40
Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 218 ITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMP-AFIFE 276
+ S+ S A GL I E+NGQN ++ S+ +IL + T ++IT+ F+F+
Sbjct: 413 VDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEIL-RNNTHLSITVKTNLFVFK 471
Query: 277 HIIKRMA 283
++ R++
Sbjct: 472 ELLTRLS 478
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 41.6 bits (96), Expect = 9e-04
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Query: 135 GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRP 194
GI+V V S A GL +GDQ+L+ NG N + +A ++ Q + IT+ + P
Sbjct: 1371 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQC-DTITILAQYNP 1429
Query: 195 FERTITMHKDSTGHV 209
++ H S+ H+
Sbjct: 1430 HVHQLSSHSRSSSHL 1444
Score = 29.6 bits (65), Expect = 3.4
Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 131 SIDNGIFVQLVQANSPASLVG-LRFGDQVLQING 163
S++NG++ V SPA+ G L GD+++ ING
Sbjct: 733 SLENGVYAAAVLPGSPAAKEGSLAVGDRIVAING 766
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,271,301
Number of Sequences: 37866
Number of extensions: 426737
Number of successful extensions: 1318
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 1069
Number of HSP's gapped (non-prelim): 311
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.