Guide to the Human Genome
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Name: RAPGEF2 Sequence: fasta or formatted (1499aa) NCBI GI: 7657261
Description:

Rap guanine nucleotide exchange factor 2

Referenced in:

PDZ Domain
Ras

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6         84           2
 C cysteine            1.0         15           1
 D aspartate           6.2         93           4
 E glutamate           7.2        108           3
 F phenylalanine       3.1         46           1
 G glycine             5.5         82           2
 H histidine           2.7         40           2
 I isoleucine          5.1         76           2
 K lysine              6.3         95           3
 L leucine             8.9        133           2
 M methionine          2.7         40           1
 N asparagine          4.1         61           2
 P proline             5.9         88           3
 Q glutamine           5.1         76           3
 R arginine            5.9         89           2
 S serine             10.5        158           3
 T threonine           5.7         86           2
 V valine              5.9         89           2
 W tryptophan          0.8         12           1
 Y tyrosine            1.9         28           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rap guanine nucleotide exchange factor 2 
RAPGEF6               0.591   PDZ domain-containing guanine nucleotide exchange fa...
LOC100133567          0.529   PREDICTED: similar to Rap guanine nucleotide exchan...
RAPGEF5               0.048   Rap guanine nucleotide exchange factor (GEF) 5 [Hom...
RAPGEF4               0.048   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEF4               0.048   Rap guanine nucleotide exchange factor (GEF) 4 isof...
RAPGEFL1              0.045   Rap guanine nucleotide exchange factor (GEF)-like 1 [...
RAPGEF3               0.044   Rap guanine nucleotide exchange factor 3 isoform b ...
RAPGEF3               0.044   Rap guanine nucleotide exchange factor 3 isoform b [...
RAPGEF3               0.044   Rap guanine nucleotide exchange factor 3 isoform a ...
RAPGEF1               0.026   guanine nucleotide-releasing factor 2 isoform b [Hom...
RAPGEF1               0.026   guanine nucleotide-releasing factor 2 isoform a [Hom...
RASGEF1B              0.026   RasGEF domain family, member 1B 
RASGEF1C              0.026   RasGEF domain family, member 1C 
RASGEF1A              0.024   RasGEF domain family, member 1A 
RASGRF1               0.023   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.023   Ras protein-specific guanine nucleotide-releasing fa...
RASGRF1               0.023   Ras protein-specific guanine nucleotide-releasing fa...
RALGPS2               0.022   Ral GEF with PH domain and SH3 binding motif 2 [Homo...
RASGRF2               0.022   Ras protein-specific guanine nucleotide-releasing fa...
SOS1                  0.021   son of sevenless homolog 1 
RALGPS1               0.021   Ral GEF with PH domain and SH3 binding motif 1 
SOS2                  0.018   son of sevenless homolog 2 
RGL1                  0.017   ral guanine nucleotide dissociation stimulator-like ...
RALGDS                0.017   ral guanine nucleotide dissociation stimulator isofo...
RALGDS                0.017   ral guanine nucleotide dissociation stimulator isof...
RASGRP1               0.016   RAS guanyl releasing protein 1 isoform b 
RASGRP1               0.016   RAS guanyl releasing protein 1 isoform a 
PDZD7                 0.016   PDZ domain containing 7 
RASGRP4               0.015   RAS guanyl releasing protein 4 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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