Guide to the Human Genome
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Name: ARHGEF12 Sequence: fasta or formatted (1544aa) NCBI GI: 7662088
Description:

Rho guanine nucleotide exchange factor (GEF) 12

Referenced in:

Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.2         81           3
 C cysteine            1.1         17           1
 D aspartate           6.5        100           3
 E glutamate           9.0        139           3
 F phenylalanine       2.7         42           2
 G glycine             5.4         84           2
 H histidine           3.2         49           2
 I isoleucine          4.8         74           2
 K lysine              6.5        100           2
 L leucine             9.1        141           3
 M methionine          2.1         32           1
 N asparagine          3.0         47           2
 P proline             5.8         89           4
 Q glutamine           6.3         98           3
 R arginine            5.6         87           2
 S serine              9.5        146           3
 T threonine           5.9         91           1
 V valine              5.8         90           2
 W tryptophan          0.5          8           1
 Y tyrosine            1.9         29           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho guanine nucleotide exchange factor (GEF) 12 [Homo... 
ARHGEF11              0.220   Rho guanine nucleotide exchange factor (GEF) 11 isof...
ARHGEF11              0.209   Rho guanine nucleotide exchange factor (GEF) 11 isofo...
ARHGEF1               0.164   Rho guanine nucleotide exchange factor 1 isoform 1 [...
ARHGEF1               0.164   Rho guanine nucleotide exchange factor 1 isoform 2 [...
ARHGEF1               0.150   Rho guanine nucleotide exchange factor 1 isoform 3 [...
ARHGEF18              0.052   Rho/Rac guanine nucleotide exchange factor 18 isofo...
ARHGEF18              0.052   Rho/Rac guanine nucleotide exchange factor 18 isofor...
ARHGEF2               0.048   Rho/Rac guanine nucleotide exchange factor 2 isofor...
ARHGEF2               0.048   Rho/Rac guanine nucleotide exchange factor 2 isoofor...
ARHGEF2               0.048   Rho/Rac guanine nucleotide exchange factor 2 isofor...
AKAP13                0.047   A-kinase anchor protein 13 isoform 1 
AKAP13                0.047   A-kinase anchor protein 13 isoform 3 
AKAP13                0.047   A-kinase anchor protein 13 isoform 2 
RGNEF                 0.047   Rho-guanine nucleotide exchange factor 
PLEKHG5               0.039   pleckstrin homology domain containing family G membe...
PLEKHG5               0.039   pleckstrin homology domain containing family G memb...
PLEKHG5               0.039   pleckstrin homology domain containing family G memb...
PLEKHG5               0.039   pleckstrin homology domain containing family G memb...
PLEKHG5               0.039   pleckstrin homology domain containing family G memb...
ITSN2                 0.033   intersectin 2 isoform 3 
ITSN2                 0.033   intersectin 2 isoform 1 
ITSN1                 0.031   intersectin 1 isoform ITSN-l 
NET1                  0.021   neuroepithelial cell transforming gene 1 isoform 1 ...
NET1                  0.021   neuroepithelial cell transforming gene 1 isoform 2 [...
ARHGEF3               0.021   Rho guanine nucleotide exchange factor 3 isoform 2 ...
ARHGEF3               0.021   Rho guanine nucleotide exchange factor 3 isoform 1 ...
ARHGEF3               0.021   Rho guanine nucleotide exchange factor 3 isoform 3 [H...
PLEKHG6               0.020   pleckstrin homology domain-containing family G memb...
PLEKHG6               0.020   pleckstrin homology domain-containing family G memb...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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