Guide to the Human Genome
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Search of human proteins with 55925576

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55925576 insulin-like growth factor binding protein 2, 36kDa
[Homo sapiens]
         (328 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55925576 insulin-like growth factor binding protein 2, 36kDa ...   699   0.0  
gi|62243290 insulin-like growth factor binding protein 4 precurs...   177   1e-44
gi|62243068 insulin-like growth factor binding protein 3 isoform...   151   7e-37
gi|4504615 insulin-like growth factor binding protein 1 precurso...   151   9e-37
gi|62243248 insulin-like growth factor binding protein 3 isoform...   149   3e-36
gi|10834982 insulin-like growth factor binding protein 5 [Homo s...   142   3e-34
gi|11321593 insulin-like growth factor binding protein 6 [Homo s...   115   7e-26
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]            57   2e-08
gi|56090548 insulin-like growth factor binding protein-like 1 [H...    51   1e-06
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]              45   1e-04
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ...    44   2e-04
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu...    44   2e-04
gi|115298674 nidogen 1 precursor [Homo sapiens]                        43   3e-04
gi|5901946 endothelial cell-specific molecule 1 isoform a precur...    43   4e-04
gi|208022668 endothelial cell-specific molecule 1 isoform b prec...    43   4e-04
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa...    43   4e-04
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo...    42   6e-04
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo...    42   0.001
gi|93141003 testican 3 isoform 1 [Homo sapiens]                        42   0.001
gi|93141001 testican 3 isoform 2 [Homo sapiens]                        42   0.001
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]       41   0.002
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]                41   0.002
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]     41   0.002
gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens]           40   0.002
gi|39812378 RAN binding protein 9 [Homo sapiens]                       40   0.003
gi|78190498 secreted modular calcium-binding protein 1 isoform 1...    40   0.003
gi|11545873 secreted modular calcium-binding protein 1 isoform 2...    40   0.003
gi|169218303 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004
gi|22129776 HtrA serine peptidase 3 [Homo sapiens]                     39   0.005
gi|68448544 CD74 antigen isoform a [Homo sapiens]                      39   0.006

>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
           [Homo sapiens]
          Length = 328

 Score =  699 bits (1805), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MLPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPP 60
           MLPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPP
Sbjct: 1   MLPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPP 60

Query: 61  VAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGS 120
           VAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGS
Sbjct: 61  VAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGS 120

Query: 121 ELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAG 180
           ELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAG
Sbjct: 121 ELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAG 180

Query: 181 RKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER 240
           RKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER
Sbjct: 181 RKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER 240

Query: 241 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA 300
           ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA
Sbjct: 241 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA 300

Query: 301 PTIRGDPECHLFYNEQQEARGVHTQRMQ 328
           PTIRGDPECHLFYNEQQEARGVHTQRMQ
Sbjct: 301 PTIRGDPECHLFYNEQQEARGVHTQRMQ 328


>gi|62243290 insulin-like growth factor binding protein 4 precursor
           [Homo sapiens]
          Length = 258

 Score =  177 bits (449), Expect = 1e-44
 Identities = 112/294 (38%), Positives = 150/294 (51%), Gaps = 44/294 (14%)

Query: 17  LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76
           +LPL  +  LLL A  G G +  +    CPPC+ E+LA C PP                +
Sbjct: 1   MLPLCLVAALLLAA--GPGPSLGDEAIHCPPCSEEKLARCRPP----------------V 42

Query: 77  PCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEK 136
            C ELVREPGCGCC+ CA   G  CGVYTPRCG GLRCYP  G E PL  L+ G+G C +
Sbjct: 43  GCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCME 102

Query: 137 RRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFRE 196
              AE  A  E +  +  D  EG       D   N      +  R+ L+   K  A  R+
Sbjct: 103 L--AEIEAIQESLQPS--DKDEG-------DHPNNSFSPCSAHDRRCLQ---KHFAKIRD 148

Query: 197 KVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHL 256
           + T        GGK  +     +  RP P +  CQ EL + LER++      +    E L
Sbjct: 149 RST-------SGGKMKVNGAPREDARPVP-QGSCQSELHRALERLAA----SQSRTHEDL 196

Query: 257 YSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECH 310
           Y + IPNCD++G ++ KQC  +L+GQRG+CWCV+  TG  + G    +G+ +CH
Sbjct: 197 YIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCH 250


>gi|62243068 insulin-like growth factor binding protein 3 isoform b
           precursor [Homo sapiens]
          Length = 291

 Score =  151 bits (382), Expect = 7e-37
 Identities = 99/306 (32%), Positives = 138/306 (45%), Gaps = 46/306 (15%)

Query: 21  LPLLLLLLG---ASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMP 77
           L LL+LL G   A  G   A    + RC PC    LA C PPP                 
Sbjct: 13  LTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAV--------------- 57

Query: 78  CAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKR 137
           CAELVREPGCGCC  CA  EG+ CG+YT RCG GLRC P P    PLQAL+ G G C   
Sbjct: 58  CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117

Query: 138 RDAE--------YGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMK 189
                          +P   +++ +D S G +    V ST  +          PL S + 
Sbjct: 118 SAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRV----SDPKFHPLHSKII 173

Query: 190 ELAVFREKVTEQHR---QMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRL 246
            +     K +++++   +       +   E  ++        PC++E++  L  +  + +
Sbjct: 174 IIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETE----YGPCRREMEDTLNHLKFLNV 229

Query: 247 PDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGD 306
              RG       +HIPNCDK G Y  KQC+ S   +RG CWCV+   G+ + G  T +G 
Sbjct: 230 LSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPGY-TTKGK 280

Query: 307 PECHLF 312
            + H +
Sbjct: 281 EDVHCY 286


>gi|4504615 insulin-like growth factor binding protein 1 precursor
           [Homo sapiens]
          Length = 259

 Score =  151 bits (381), Expect = 9e-37
 Identities = 93/294 (31%), Positives = 146/294 (49%), Gaps = 46/294 (15%)

Query: 23  LLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELV 82
           L+LLLL    G     A   ++C PC+ E+LA C  PPV+               C+E+ 
Sbjct: 11  LVLLLLTVQVG---VTAGAPWQCAPCSAEKLALC--PPVSAS-------------CSEVT 52

Query: 83  REPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEY 142
           R  GCGCC +CA   G ACGV T RC +GL C   PG + PL AL  G+G C +  DA  
Sbjct: 53  RSAGCGCCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASA 112

Query: 143 GASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQH 202
             + E  +    + +E  + E  +    +++               ++ ++  + ++   
Sbjct: 113 PHAAEAGSPESPESTE--ITEEELLDNFHLMA-----------PSEEDHSILWDAISTYD 159

Query: 203 RQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIP 262
              G    H   +++ K+        PC+ EL +V+E  S  +  +  G  E +   ++P
Sbjct: 160 ---GSKALHVTNIKKWKE--------PCRIELYRVVE--SLAKAQETSG--EEISKFYLP 204

Query: 263 NCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQ 316
           NC+K+G Y+ +QC+ S++G+ G CWCV P  GK I G+P IRGDP C +++N Q
Sbjct: 205 NCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQ 258


>gi|62243248 insulin-like growth factor binding protein 3 isoform a
           precursor [Homo sapiens]
          Length = 297

 Score =  149 bits (376), Expect = 3e-36
 Identities = 99/312 (31%), Positives = 138/312 (44%), Gaps = 52/312 (16%)

Query: 21  LPLLLLLLG---ASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMP 77
           L LL+LL G   A  G   A    + RC PC    LA C PPP                 
Sbjct: 13  LTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAV--------------- 57

Query: 78  CAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKR 137
           CAELVREPGCGCC  CA  EG+ CG+YT RCG GLRC P P    PLQAL+ G G C   
Sbjct: 58  CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117

Query: 138 RDAE--------------YGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKP 183
                                +P   +++ +D S G +    V ST  +          P
Sbjct: 118 SAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRV----SDPKFHP 173

Query: 184 LKSGMKELAVFREKVTEQHR---QMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER 240
           L S +  +     K +++++   +       +   E  ++        PC++E++  L  
Sbjct: 174 LHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETE----YGPCRREMEDTLNH 229

Query: 241 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA 300
           +  + +   RG       +HIPNCDK G Y  KQC+ S   +RG CWCV+   G+ + G 
Sbjct: 230 LKFLNVLSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPGY 281

Query: 301 PTIRGDPECHLF 312
            T +G  + H +
Sbjct: 282 -TTKGKEDVHCY 292


>gi|10834982 insulin-like growth factor binding protein 5 [Homo
           sapiens]
          Length = 272

 Score =  142 bits (359), Expect = 3e-34
 Identities = 90/305 (29%), Positives = 136/305 (44%), Gaps = 41/305 (13%)

Query: 20  LLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCA 79
           LL  +LLLL A  G   +    +  C PC  + L+ C P P+                  
Sbjct: 3   LLTAVLLLLAAYAGPAQSLGSFV-HCEPCDEKALSMCPPSPLG----------------C 45

Query: 80  ELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRD 139
           ELV+EPGCGCC  CA  EG++CGVYT RC QGLRC P    E PL AL+ G G C   + 
Sbjct: 46  ELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKS 105

Query: 140 AEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAV------ 193
                  E+ +   ++ +   + E      +           +P  + + EL        
Sbjct: 106 YREQVKIERDSREHEEPTTSEMAEETYSPKI----------FRPKHTRISELKAEAVKKD 155

Query: 194 FREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPL 253
            R+K+T+     G     H  +    ++R    + PC++ ++  L+ +       +  P 
Sbjct: 156 RRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQEL-------KASPR 208

Query: 254 EHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFY 313
               ++++PNCD+ G Y  KQCK S   +RG CWCV+   G  + G   + GD +CH F 
Sbjct: 209 MVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFD 267

Query: 314 NEQQE 318
           +   E
Sbjct: 268 SSNVE 272


>gi|11321593 insulin-like growth factor binding protein 6 [Homo
           sapiens]
          Length = 240

 Score =  115 bits (287), Expect = 7e-26
 Identities = 93/298 (31%), Positives = 123/298 (41%), Gaps = 75/298 (25%)

Query: 17  LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76
           L PLL LL LLL AS GG       L RCP C     A C      P   V    GG+  
Sbjct: 7   LPPLLLLLALLLAASPGGA------LARCPGCGQGVQAGC------PGGCVEEEDGGSPA 54

Query: 77  PCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEK 136
                    GC     C R EG+ CGVYTP C  GL+C+P    E PL+AL++G G C  
Sbjct: 55  E--------GCAEAEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLP 106

Query: 137 RRDAEYGASPEQVADN-GDDHSEGGLVE----NHVDSTMNMLGGGGSAGRKPLKSGMKEL 191
            R      +P    +N  +   + G       N  D   N   G  +   +P  +G+   
Sbjct: 107 AR------APAVAEENPKESKPQAGTARPQDVNRRDQQRN--PGTSTTPSQPNSAGV--- 155

Query: 192 AVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERG 251
                    Q  +MG                      PC++ LD VL+++ T      RG
Sbjct: 156 ---------QDTEMG----------------------PCRRHLDSVLQQLQT---EVYRG 181

Query: 252 PLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPEC 309
                 +L++PNCD  G Y  +QC+ S   +RG CWCV+   GK + G+P   G   C
Sbjct: 182 ----AQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVD-RMGKSLPGSPDGNGSSSC 234


>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
          Length = 480

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 39/104 (37%), Positives = 43/104 (41%), Gaps = 23/104 (22%)

Query: 16  PLLPLLPLLLLLLGASGGG----GGARAEVLFRCPP-CTPERLAACGPPPVAPPAAVAAV 70
           P   LLPLLLLLL A         G  A +   CP  C P R          PP      
Sbjct: 4   PRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPAR---------CPPQPEHCE 54

Query: 71  AGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRC 114
            G AR           CGCC VC   EG ACG+    CG+GL+C
Sbjct: 55  GGRAR---------DACGCCEVCGAPEGAACGLQEGPCGEGLQC 89


>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
           sapiens]
          Length = 278

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 44/134 (32%), Positives = 52/134 (38%), Gaps = 29/134 (21%)

Query: 2   LPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPV 61
           +PR+    LPL    LLPLLP L   LG    GG        +C PC PE    C  P  
Sbjct: 1   MPRLSL-LLPLLLLLLLPLLPPLSPSLGIRDVGGRRP-----KCGPCRPE---GCPAPAP 51

Query: 62  APPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYT-PRCGQGLRCYPHPGS 120
            P   ++A+                CGCC+ C   EG +CG     RCG GL C      
Sbjct: 52  CPAPGISAL--------------DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAG 97

Query: 121 ELPLQALVMGEGTC 134
             P      G G C
Sbjct: 98  AAP-----EGTGLC 106


>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
          Length = 422

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 44/124 (35%), Positives = 52/124 (41%), Gaps = 14/124 (11%)

Query: 14  PPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCT---PERLAAC---GPPPVAPPAAV 67
           PPPLLPLL LLL +LGA   G GA   V+    P        LA C   G PP A    +
Sbjct: 16  PPPLLPLL-LLLCVLGAPRAGSGAHTAVISPQDPTLLIGSSLLATCSVHGDPPGATAEGL 74

Query: 68  AAVAGGARMPCAELVREPGCGCCSVC-ARLEGEACGVYTPRCGQGLRCYPHPGSELPLQA 126
                G R+P  EL R       ++  A L G        R G  L C+   GS L    
Sbjct: 75  YWTLNGRRLP-PELSRVLNASTLALALANLNGS-----RQRSGDNLVCHARDGSILAGSC 128

Query: 127 LVMG 130
           L +G
Sbjct: 129 LYVG 132


>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
           [Homo sapiens]
          Length = 250

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 23/95 (24%)

Query: 45  CP-PCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACG- 102
           CP PCT      C  PP   P  V  V  G             CGCC VCAR  GE C  
Sbjct: 26  CPTPCT------CPWPPPRCPLGVPLVLDG-------------CGCCRVCARRLGEPCDQ 66

Query: 103 VYTPRCGQGLRCYP--HPGSELPLQALVMGEGTCE 135
           ++     QGL C P   PG    L  L   + +CE
Sbjct: 67  LHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCE 101


>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
           precursor [Homo sapiens]
          Length = 304

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 40/134 (29%), Positives = 49/134 (36%), Gaps = 40/134 (29%)

Query: 10  LPLPPPPLLPLLPLLLLLLGA-----SGGGGGARAEVLFR-----------CPPCTPERL 53
           LP P P     LP+LLLLL       +G       + L R           C PC PE  
Sbjct: 2   LPPPRPAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEEC 61

Query: 54  AACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGV-----YTPRC 108
           AA              +AG  R           CGCC  CA LEG+ C +     +   C
Sbjct: 62  AA----------PRGCLAGRVR---------DACGCCWECANLEGQLCDLDPSAHFYGHC 102

Query: 109 GQGLRCYPHPGSEL 122
           G+ L C    G +L
Sbjct: 103 GEQLECRLDTGGDL 116


>gi|115298674 nidogen 1 precursor [Homo sapiens]
          Length = 1247

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 11/84 (13%)

Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286
           +T CQ E + +L         D + P+     L +P CD HG Y   QC    +G  G C
Sbjct: 846 KTRCQHEREHILGAAGAT---DPQRPIPP--GLFVPECDAHGHYAPTQC----HGSTGYC 896

Query: 287 WCVNPNTGKLIQGAPTIRG-DPEC 309
           WCV+   G+ ++G  T  G  P C
Sbjct: 897 WCVD-RDGREVEGTRTRPGMTPPC 919


>gi|5901946 endothelial cell-specific molecule 1 isoform a precursor
           [Homo sapiens]
          Length = 184

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)

Query: 87  CGCCSVCARLEGEAC-----GVYTPRCGQGLRCYPHPGSE 121
           CGCC VCA   GE C     G+   +CG GLRC P  G +
Sbjct: 51  CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90


>gi|208022668 endothelial cell-specific molecule 1 isoform b
           precursor [Homo sapiens]
          Length = 134

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)

Query: 87  CGCCSVCARLEGEAC-----GVYTPRCGQGLRCYPHPGSE 121
           CGCC VCA   GE C     G+   +CG GLRC P  G +
Sbjct: 51  CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90


>gi|4504619 insulin-like growth factor binding protein 7 [Homo
           sapiens]
          Length = 282

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 35/101 (34%), Positives = 41/101 (40%), Gaps = 26/101 (25%)

Query: 17  LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76
           LL    LLLLLL  S             C PC P   A+C  PP+ P   +  + G  R 
Sbjct: 10  LLGAAGLLLLLLPLSSSSSSDT------CGPCEP---ASC--PPLPP---LGCLLGETR- 54

Query: 77  PCAELVREPGCGCCSVCARLEGEAC---GVYTPRCGQGLRC 114
                     CGCC +CAR EGE C   G     C  G+ C
Sbjct: 55  --------DACGCCPMCARGEGEPCGGGGAGRGYCAPGMEC 87


>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan (testican) 2 isoform 2 [Homo sapiens]
          Length = 424

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 16/83 (19%)

Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286
           + PC  EL+++  + +  + P           + IP+CD+ G Y   QC  S     G+C
Sbjct: 310 KPPCLAELERIQIQEAAKKKP----------GIFIPSCDEDGYYRKMQCDQS----SGDC 355

Query: 287 WCVNPNTGKLIQGAPTIRGDPEC 309
           WCV+   G  + G  T  G P+C
Sbjct: 356 WCVD-QLGLELTGTRT-HGSPDC 376


>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
           proteoglycan 1 precursor [Homo sapiens]
          Length = 439

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 18/88 (20%)

Query: 225 PARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRG 284
           P   PCQ E++++ +++S  +          L    IP C++ G Y   QC    +G  G
Sbjct: 308 PGGLPCQNEMNRI-QKLSKGK---------SLLGAFIPRCNEEGYYKATQC----HGSTG 353

Query: 285 ECWCV----NPNTGKLIQGAPTIRGDPE 308
           +CWCV    N   G   QGA +   + E
Sbjct: 354 QCWCVDKYGNELAGSRKQGAVSCEEEQE 381


>gi|93141003 testican 3 isoform 1 [Homo sapiens]
          Length = 433

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 16/81 (19%)

Query: 229 PCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWC 288
           PCQ EL  + +R    +L  +          +IP CD+ G Y   QC    +G  G+CWC
Sbjct: 313 PCQTELSNIQKRQGVKKLLGQ----------YIPLCDEDGYYKPTQC----HGSVGQCWC 358

Query: 289 VNPNTGKLIQGAPTIRGDPEC 309
           V+   G  + G+  I G  +C
Sbjct: 359 VD-RYGNEVMGS-RINGVADC 377


>gi|93141001 testican 3 isoform 2 [Homo sapiens]
          Length = 436

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 16/81 (19%)

Query: 229 PCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWC 288
           PCQ EL  + +R    +L  +          +IP CD+ G Y   QC    +G  G+CWC
Sbjct: 316 PCQTELSNIQKRQGVKKLLGQ----------YIPLCDEDGYYKPTQC----HGSVGQCWC 361

Query: 289 VNPNTGKLIQGAPTIRGDPEC 309
           V+   G  + G+  I G  +C
Sbjct: 362 VD-RYGNEVMGS-RINGVADC 380


>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
          Length = 357

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 19/73 (26%)

Query: 44  RCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGV 103
           RCPP  P R  A   PP   P   A +               GC CC VCAR  GE+C  
Sbjct: 34  RCPPQCPGRCPAT--PPTCAPGVRAVL--------------DGCSCCLVCARQRGESCSD 77

Query: 104 YTPRCGQ--GLRC 114
             P C +  GL C
Sbjct: 78  LEP-CDESSGLYC 89


>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
          Length = 1036

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 39/126 (30%)

Query: 17  LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76
           L+ LL LLLLL  +     G RA V   C PC   +   C  P   P + V  V      
Sbjct: 17  LVSLLGLLLLLARS-----GTRALV---CLPCDESK---CEEPRNCPGSIVQGV------ 59

Query: 77  PCAELVREPGCGCCSVCARLEGEAC----GVYTPRCGQGLRCYPHPGSELPLQALVMGE- 131
                     CGCC  CA    E+C    G+Y   C +GLRC   P    PL    + E 
Sbjct: 60  ----------CGCCYTCASQRNESCGGTFGIY-GTCDRGLRCVIRP----PLNGDSLTEY 104

Query: 132 --GTCE 135
             G CE
Sbjct: 105 EAGVCE 110


>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
          Length = 457

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 261 IPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEAR 320
           IP C+  G Y+  QC    +   G CWCV PN G+ I G       P C    NE+   R
Sbjct: 110 IPECNDDGTYSQVQC----HSYTGYCWCVTPN-GRPISGTAVAHKTPRCPGSVNEKLPQR 164



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 4/49 (8%)

Query: 261 IPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPEC 309
           IP C   GLY   QC  S     G CWCV  +TG+ I G  T    P+C
Sbjct: 248 IPECAHGGLYKPVQCHPST----GYCWCVLVDTGRPIPGTSTRYEQPKC 292


>gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens]
          Length = 666

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 22/31 (70%), Positives = 22/31 (70%), Gaps = 2/31 (6%)

Query: 8  PALPLPPPPLLPLLPLLLLLLGASGGGGGAR 38
          P  P PPPPLLPLLPLLLLLL   G   GAR
Sbjct: 24 PPPPPPPPPLLPLLPLLLLLL--LGAAEGAR 52



 Score = 35.0 bits (79), Expect = 0.091
 Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 4/35 (11%)

Query: 3  PRVGCPALPLPPPPLLPLLP----LLLLLLGASGG 33
          P +  P  P PPPP  PLLP    LLLLLLGA+ G
Sbjct: 16 PALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEG 50


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 49/158 (31%), Positives = 56/158 (35%), Gaps = 36/158 (22%)

Query: 12  LPPPPLLPLLPLLLLLL------------------GASGGGGGARAEVLFRCPPCTPERL 53
           L PPP   L P+  ++L                  GA G G GA A  L   PP  P   
Sbjct: 19  LSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPA 78

Query: 54  AACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLR 113
            A  PPP  PP   A+ A  A  P A     PG       A   G A G  TP    G  
Sbjct: 79  TAAPPPPPPPPPPPASAAAPASGPPA----PPG------LAAGPGPAGGAPTPALVAGSS 128

Query: 114 C---YPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQ 148
               +PH  S L  Q     E   ++R    Y A  EQ
Sbjct: 129 AAAPFPHGDSALNEQ-----EKELQRRLKRLYPAVDEQ 161



 Score = 29.6 bits (65), Expect = 3.8
 Identities = 25/71 (35%), Positives = 26/71 (36%), Gaps = 14/71 (19%)

Query: 8   PALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAP-PAA 66
           PA   PPPP  P  P       ASG             PP  P   A  GP   AP PA 
Sbjct: 77  PATAAPPPPPPPPPPPASAAAPASG-------------PPAPPGLAAGPGPAGGAPTPAL 123

Query: 67  VAAVAGGARMP 77
           VA  +  A  P
Sbjct: 124 VAGSSAAAPFP 134


>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
           [Homo sapiens]
          Length = 435

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 14/80 (17%)

Query: 230 CQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCV 289
           C QE    LE         ++ P E +    IP C   GLY   QC  S     G CWCV
Sbjct: 227 CDQERQSALEEA-------QQNPREGIV---IPECAPGGLYKPVQCHQST----GYCWCV 272

Query: 290 NPNTGKLIQGAPTIRGDPEC 309
             +TG+ + G  T    P C
Sbjct: 273 LVDTGRPLPGTSTRYVMPSC 292



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 16/83 (19%)

Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286
           ++ C+ E  Q LE+    + P E        ++ +P C + G +   QC    +   G C
Sbjct: 92  QSKCRLERAQALEQA---KKPQE--------AVFVPECGEDGSFTQVQC----HTYTGYC 136

Query: 287 WCVNPNTGKLIQGAPTIRGDPEC 309
           WCV P+ GK I G+      P C
Sbjct: 137 WCVTPD-GKPISGSSVQNKTPVC 158


>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
           [Homo sapiens]
          Length = 434

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 14/80 (17%)

Query: 230 CQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCV 289
           C QE    LE         ++ P E +    IP C   GLY   QC  S     G CWCV
Sbjct: 227 CDQERQSALEEA-------QQNPREGIV---IPECAPGGLYKPVQCHQST----GYCWCV 272

Query: 290 NPNTGKLIQGAPTIRGDPEC 309
             +TG+ + G  T    P C
Sbjct: 273 LVDTGRPLPGTSTRYVMPSC 292



 Score = 35.4 bits (80), Expect = 0.070
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 16/83 (19%)

Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286
           ++ C+ E  Q LE+    + P E        ++ +P C + G +   QC    +   G C
Sbjct: 92  QSKCRLERAQALEQA---KKPQE--------AVFVPECGEDGSFTQVQC----HTYTGYC 136

Query: 287 WCVNPNTGKLIQGAPTIRGDPEC 309
           WCV P+ GK I G+      P C
Sbjct: 137 WCVTPD-GKPISGSSVQNKTPVC 158


>gi|169218303 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 421

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 35/104 (33%), Positives = 45/104 (43%), Gaps = 14/104 (13%)

Query: 41  VLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEA 100
           VLF+   C+P  + A      A    +   + GA   C  L    GCGCCS   RL    
Sbjct: 283 VLFQAVRCSPVGVGA------ASGCQMLTWSVGAAPGCQMLAW--GCGCCS---RLSDAH 331

Query: 101 CGVYTPRCGQGLRCYPHPGSELP-LQALVMGEGTCEKRRDAEYG 143
            GV+     Q LRC P     +P  Q L  G G+C +  DA +G
Sbjct: 332 LGVWV--LLQALRCSPGCVGAIPGYQMLTWGCGSCSRLSDAHFG 373


>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
          Length = 453

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 1/63 (1%)

Query: 53  LAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEAC-GVYTPRCGQG 111
           LA    PP AP  A   V+      C        C CC VCA  EGE C G     CG+ 
Sbjct: 14  LALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGGPLDSPCGES 73

Query: 112 LRC 114
           L C
Sbjct: 74  LEC 76


>gi|68448544 CD74 antigen isoform a [Homo sapiens]
          Length = 296

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 19/78 (24%)

Query: 215 LEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQ 274
           LE+     PP   T CQ+E+  +              P  H  S   P CD++G Y   Q
Sbjct: 198 LEQKPTDAPPKVLTKCQEEVSHI--------------PAVHPGSFR-PKCDENGNYLPLQ 242

Query: 275 CKMSLNGQRGECWCVNPN 292
           C  S+    G CWCV PN
Sbjct: 243 CYGSI----GYCWCVFPN 256


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.140    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,748,461
Number of Sequences: 37866
Number of extensions: 1057831
Number of successful extensions: 6932
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 6267
Number of HSP's gapped (non-prelim): 688
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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