BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55925576 insulin-like growth factor binding protein 2, 36kDa [Homo sapiens] (328 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 699 0.0 gi|62243290 insulin-like growth factor binding protein 4 precurs... 177 1e-44 gi|62243068 insulin-like growth factor binding protein 3 isoform... 151 7e-37 gi|4504615 insulin-like growth factor binding protein 1 precurso... 151 9e-37 gi|62243248 insulin-like growth factor binding protein 3 isoform... 149 3e-36 gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 142 3e-34 gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 115 7e-26 gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 57 2e-08 gi|56090548 insulin-like growth factor binding protein-like 1 [H... 51 1e-06 gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 45 1e-04 gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 44 2e-04 gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 44 2e-04 gi|115298674 nidogen 1 precursor [Homo sapiens] 43 3e-04 gi|5901946 endothelial cell-specific molecule 1 isoform a precur... 43 4e-04 gi|208022668 endothelial cell-specific molecule 1 isoform b prec... 43 4e-04 gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 43 4e-04 gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 42 6e-04 gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 42 0.001 gi|93141003 testican 3 isoform 1 [Homo sapiens] 42 0.001 gi|93141001 testican 3 isoform 2 [Homo sapiens] 42 0.001 gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] 41 0.002 gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 41 0.002 gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 41 0.002 gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens] 40 0.002 gi|39812378 RAN binding protein 9 [Homo sapiens] 40 0.003 gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 40 0.003 gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 40 0.003 gi|169218303 PREDICTED: hypothetical protein [Homo sapiens] 40 0.004 gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 39 0.005 gi|68448544 CD74 antigen isoform a [Homo sapiens] 39 0.006 >gi|55925576 insulin-like growth factor binding protein 2, 36kDa [Homo sapiens] Length = 328 Score = 699 bits (1805), Expect = 0.0 Identities = 328/328 (100%), Positives = 328/328 (100%) Query: 1 MLPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPP 60 MLPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPP Sbjct: 1 MLPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPP 60 Query: 61 VAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGS 120 VAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGS Sbjct: 61 VAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGS 120 Query: 121 ELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAG 180 ELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAG Sbjct: 121 ELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAG 180 Query: 181 RKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER 240 RKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER Sbjct: 181 RKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER 240 Query: 241 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA 300 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA Sbjct: 241 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA 300 Query: 301 PTIRGDPECHLFYNEQQEARGVHTQRMQ 328 PTIRGDPECHLFYNEQQEARGVHTQRMQ Sbjct: 301 PTIRGDPECHLFYNEQQEARGVHTQRMQ 328 >gi|62243290 insulin-like growth factor binding protein 4 precursor [Homo sapiens] Length = 258 Score = 177 bits (449), Expect = 1e-44 Identities = 112/294 (38%), Positives = 150/294 (51%), Gaps = 44/294 (14%) Query: 17 LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76 +LPL + LLL A G G + + CPPC+ E+LA C PP + Sbjct: 1 MLPLCLVAALLLAA--GPGPSLGDEAIHCPPCSEEKLARCRPP----------------V 42 Query: 77 PCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEK 136 C ELVREPGCGCC+ CA G CGVYTPRCG GLRCYP G E PL L+ G+G C + Sbjct: 43 GCEELVREPGCGCCATCALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCME 102 Query: 137 RRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFRE 196 AE A E + + D EG D N + R+ L+ K A R+ Sbjct: 103 L--AEIEAIQESLQPS--DKDEG-------DHPNNSFSPCSAHDRRCLQ---KHFAKIRD 148 Query: 197 KVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHL 256 + T GGK + + RP P + CQ EL + LER++ + E L Sbjct: 149 RST-------SGGKMKVNGAPREDARPVP-QGSCQSELHRALERLAA----SQSRTHEDL 196 Query: 257 YSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECH 310 Y + IPNCD++G ++ KQC +L+GQRG+CWCV+ TG + G +G+ +CH Sbjct: 197 YIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRKTGVKLPGGLEPKGELDCH 250 >gi|62243068 insulin-like growth factor binding protein 3 isoform b precursor [Homo sapiens] Length = 291 Score = 151 bits (382), Expect = 7e-37 Identities = 99/306 (32%), Positives = 138/306 (45%), Gaps = 46/306 (15%) Query: 21 LPLLLLLLG---ASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMP 77 L LL+LL G A G A + RC PC LA C PPP Sbjct: 13 LTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAV--------------- 57 Query: 78 CAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKR 137 CAELVREPGCGCC CA EG+ CG+YT RCG GLRC P P PLQAL+ G G C Sbjct: 58 CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117 Query: 138 RDAE--------YGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMK 189 +P +++ +D S G + V ST + PL S + Sbjct: 118 SAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRV----SDPKFHPLHSKII 173 Query: 190 ELAVFREKVTEQHR---QMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRL 246 + K +++++ + + E ++ PC++E++ L + + + Sbjct: 174 IIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETE----YGPCRREMEDTLNHLKFLNV 229 Query: 247 PDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGD 306 RG +HIPNCDK G Y KQC+ S +RG CWCV+ G+ + G T +G Sbjct: 230 LSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPGY-TTKGK 280 Query: 307 PECHLF 312 + H + Sbjct: 281 EDVHCY 286 >gi|4504615 insulin-like growth factor binding protein 1 precursor [Homo sapiens] Length = 259 Score = 151 bits (381), Expect = 9e-37 Identities = 93/294 (31%), Positives = 146/294 (49%), Gaps = 46/294 (15%) Query: 23 LLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELV 82 L+LLLL G A ++C PC+ E+LA C PPV+ C+E+ Sbjct: 11 LVLLLLTVQVG---VTAGAPWQCAPCSAEKLALC--PPVSAS-------------CSEVT 52 Query: 83 REPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEY 142 R GCGCC +CA G ACGV T RC +GL C PG + PL AL G+G C + DA Sbjct: 53 RSAGCGCCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASA 112 Query: 143 GASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQH 202 + E + + +E + E + +++ ++ ++ + ++ Sbjct: 113 PHAAEAGSPESPESTE--ITEEELLDNFHLMA-----------PSEEDHSILWDAISTYD 159 Query: 203 RQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIP 262 G H +++ K+ PC+ EL +V+E S + + G E + ++P Sbjct: 160 ---GSKALHVTNIKKWKE--------PCRIELYRVVE--SLAKAQETSG--EEISKFYLP 204 Query: 263 NCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQ 316 NC+K+G Y+ +QC+ S++G+ G CWCV P GK I G+P IRGDP C +++N Q Sbjct: 205 NCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQ 258 >gi|62243248 insulin-like growth factor binding protein 3 isoform a precursor [Homo sapiens] Length = 297 Score = 149 bits (376), Expect = 3e-36 Identities = 99/312 (31%), Positives = 138/312 (44%), Gaps = 52/312 (16%) Query: 21 LPLLLLLLG---ASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMP 77 L LL+LL G A G A + RC PC LA C PPP Sbjct: 13 LTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAV--------------- 57 Query: 78 CAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKR 137 CAELVREPGCGCC CA EG+ CG+YT RCG GLRC P P PLQAL+ G G C Sbjct: 58 CAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117 Query: 138 RDAE--------------YGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKP 183 +P +++ +D S G + V ST + P Sbjct: 118 SAVSRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRV----SDPKFHP 173 Query: 184 LKSGMKELAVFREKVTEQHR---QMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLER 240 L S + + K +++++ + + E ++ PC++E++ L Sbjct: 174 LHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETE----YGPCRREMEDTLNH 229 Query: 241 ISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGA 300 + + + RG +HIPNCDK G Y KQC+ S +RG CWCV+ G+ + G Sbjct: 230 LKFLNVLSPRG-------VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVD-KYGQPLPGY 281 Query: 301 PTIRGDPECHLF 312 T +G + H + Sbjct: 282 -TTKGKEDVHCY 292 >gi|10834982 insulin-like growth factor binding protein 5 [Homo sapiens] Length = 272 Score = 142 bits (359), Expect = 3e-34 Identities = 90/305 (29%), Positives = 136/305 (44%), Gaps = 41/305 (13%) Query: 20 LLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCA 79 LL +LLLL A G + + C PC + L+ C P P+ Sbjct: 3 LLTAVLLLLAAYAGPAQSLGSFV-HCEPCDEKALSMCPPSPLG----------------C 45 Query: 80 ELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRD 139 ELV+EPGCGCC CA EG++CGVYT RC QGLRC P E PL AL+ G G C + Sbjct: 46 ELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKS 105 Query: 140 AEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAV------ 193 E+ + ++ + + E + +P + + EL Sbjct: 106 YREQVKIERDSREHEEPTTSEMAEETYSPKI----------FRPKHTRISELKAEAVKKD 155 Query: 194 FREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPL 253 R+K+T+ G H + ++R + PC++ ++ L+ + + P Sbjct: 156 RRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQEL-------KASPR 208 Query: 254 EHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFY 313 ++++PNCD+ G Y KQCK S +RG CWCV+ G + G + GD +CH F Sbjct: 209 MVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFD 267 Query: 314 NEQQE 318 + E Sbjct: 268 SSNVE 272 >gi|11321593 insulin-like growth factor binding protein 6 [Homo sapiens] Length = 240 Score = 115 bits (287), Expect = 7e-26 Identities = 93/298 (31%), Positives = 123/298 (41%), Gaps = 75/298 (25%) Query: 17 LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76 L PLL LL LLL AS GG L RCP C A C P V GG+ Sbjct: 7 LPPLLLLLALLLAASPGGA------LARCPGCGQGVQAGC------PGGCVEEEDGGSPA 54 Query: 77 PCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEK 136 GC C R EG+ CGVYTP C GL+C+P E PL+AL++G G C Sbjct: 55 E--------GCAEAEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLP 106 Query: 137 RRDAEYGASPEQVADN-GDDHSEGGLVE----NHVDSTMNMLGGGGSAGRKPLKSGMKEL 191 R +P +N + + G N D N G + +P +G+ Sbjct: 107 AR------APAVAEENPKESKPQAGTARPQDVNRRDQQRN--PGTSTTPSQPNSAGV--- 155 Query: 192 AVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERG 251 Q +MG PC++ LD VL+++ T RG Sbjct: 156 ---------QDTEMG----------------------PCRRHLDSVLQQLQT---EVYRG 181 Query: 252 PLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPEC 309 +L++PNCD G Y +QC+ S +RG CWCV+ GK + G+P G C Sbjct: 182 ----AQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVD-RMGKSLPGSPDGNGSSSC 234 >gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] Length = 480 Score = 57.0 bits (136), Expect = 2e-08 Identities = 39/104 (37%), Positives = 43/104 (41%), Gaps = 23/104 (22%) Query: 16 PLLPLLPLLLLLLGASGGG----GGARAEVLFRCPP-CTPERLAACGPPPVAPPAAVAAV 70 P LLPLLLLLL A G A + CP C P R PP Sbjct: 4 PRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPAR---------CPPQPEHCE 54 Query: 71 AGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRC 114 G AR CGCC VC EG ACG+ CG+GL+C Sbjct: 55 GGRAR---------DACGCCEVCGAPEGAACGLQEGPCGEGLQC 89 >gi|56090548 insulin-like growth factor binding protein-like 1 [Homo sapiens] Length = 278 Score = 51.2 bits (121), Expect = 1e-06 Identities = 44/134 (32%), Positives = 52/134 (38%), Gaps = 29/134 (21%) Query: 2 LPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPV 61 +PR+ LPL LLPLLP L LG GG +C PC PE C P Sbjct: 1 MPRLSL-LLPLLLLLLLPLLPPLSPSLGIRDVGGRRP-----KCGPCRPE---GCPAPAP 51 Query: 62 APPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYT-PRCGQGLRCYPHPGS 120 P ++A+ CGCC+ C EG +CG RCG GL C Sbjct: 52 CPAPGISAL--------------DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAG 97 Query: 121 ELPLQALVMGEGTC 134 P G G C Sbjct: 98 AAP-----EGTGLC 106 >gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] Length = 422 Score = 44.7 bits (104), Expect = 1e-04 Identities = 44/124 (35%), Positives = 52/124 (41%), Gaps = 14/124 (11%) Query: 14 PPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCT---PERLAAC---GPPPVAPPAAV 67 PPPLLPLL LLL +LGA G GA V+ P LA C G PP A + Sbjct: 16 PPPLLPLL-LLLCVLGAPRAGSGAHTAVISPQDPTLLIGSSLLATCSVHGDPPGATAEGL 74 Query: 68 AAVAGGARMPCAELVREPGCGCCSVC-ARLEGEACGVYTPRCGQGLRCYPHPGSELPLQA 126 G R+P EL R ++ A L G R G L C+ GS L Sbjct: 75 YWTLNGRRLP-PELSRVLNASTLALALANLNGS-----RQRSGDNLVCHARDGSILAGSC 128 Query: 127 LVMG 130 L +G Sbjct: 129 LYVG 132 >gi|4507923 WNT1 inducible signaling pathway protein 2 precursor [Homo sapiens] Length = 250 Score = 43.9 bits (102), Expect = 2e-04 Identities = 34/95 (35%), Positives = 38/95 (40%), Gaps = 23/95 (24%) Query: 45 CP-PCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACG- 102 CP PCT C PP P V V G CGCC VCAR GE C Sbjct: 26 CPTPCT------CPWPPPRCPLGVPLVLDG-------------CGCCRVCARRLGEPCDQ 66 Query: 103 VYTPRCGQGLRCYP--HPGSELPLQALVMGEGTCE 135 ++ QGL C P PG L L + +CE Sbjct: 67 LHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCE 101 >gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precursor [Homo sapiens] Length = 304 Score = 43.9 bits (102), Expect = 2e-04 Identities = 40/134 (29%), Positives = 49/134 (36%), Gaps = 40/134 (29%) Query: 10 LPLPPPPLLPLLPLLLLLLGA-----SGGGGGARAEVLFR-----------CPPCTPERL 53 LP P P LP+LLLLL +G + L R C PC PE Sbjct: 2 LPPPRPAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEEC 61 Query: 54 AACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGV-----YTPRC 108 AA +AG R CGCC CA LEG+ C + + C Sbjct: 62 AA----------PRGCLAGRVR---------DACGCCWECANLEGQLCDLDPSAHFYGHC 102 Query: 109 GQGLRCYPHPGSEL 122 G+ L C G +L Sbjct: 103 GEQLECRLDTGGDL 116 >gi|115298674 nidogen 1 precursor [Homo sapiens] Length = 1247 Score = 43.1 bits (100), Expect = 3e-04 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 11/84 (13%) Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286 +T CQ E + +L D + P+ L +P CD HG Y QC +G G C Sbjct: 846 KTRCQHEREHILGAAGAT---DPQRPIPP--GLFVPECDAHGHYAPTQC----HGSTGYC 896 Query: 287 WCVNPNTGKLIQGAPTIRG-DPEC 309 WCV+ G+ ++G T G P C Sbjct: 897 WCVD-RDGREVEGTRTRPGMTPPC 919 >gi|5901946 endothelial cell-specific molecule 1 isoform a precursor [Homo sapiens] Length = 184 Score = 42.7 bits (99), Expect = 4e-04 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Query: 87 CGCCSVCARLEGEAC-----GVYTPRCGQGLRCYPHPGSE 121 CGCC VCA GE C G+ +CG GLRC P G + Sbjct: 51 CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90 >gi|208022668 endothelial cell-specific molecule 1 isoform b precursor [Homo sapiens] Length = 134 Score = 42.7 bits (99), Expect = 4e-04 Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%) Query: 87 CGCCSVCARLEGEAC-----GVYTPRCGQGLRCYPHPGSE 121 CGCC VCA GE C G+ +CG GLRC P G + Sbjct: 51 CGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGED 90 >gi|4504619 insulin-like growth factor binding protein 7 [Homo sapiens] Length = 282 Score = 42.7 bits (99), Expect = 4e-04 Identities = 35/101 (34%), Positives = 41/101 (40%), Gaps = 26/101 (25%) Query: 17 LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76 LL LLLLLL S C PC P A+C PP+ P + + G R Sbjct: 10 LLGAAGLLLLLLPLSSSSSSDT------CGPCEP---ASC--PPLPP---LGCLLGETR- 54 Query: 77 PCAELVREPGCGCCSVCARLEGEAC---GVYTPRCGQGLRC 114 CGCC +CAR EGE C G C G+ C Sbjct: 55 --------DACGCCPMCARGEGEPCGGGGAGRGYCAPGMEC 87 >gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 isoform 2 [Homo sapiens] Length = 424 Score = 42.4 bits (98), Expect = 6e-04 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 16/83 (19%) Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286 + PC EL+++ + + + P + IP+CD+ G Y QC S G+C Sbjct: 310 KPPCLAELERIQIQEAAKKKP----------GIFIPSCDEDGYYRKMQCDQS----SGDC 355 Query: 287 WCVNPNTGKLIQGAPTIRGDPEC 309 WCV+ G + G T G P+C Sbjct: 356 WCVD-QLGLELTGTRT-HGSPDC 376 >gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 precursor [Homo sapiens] Length = 439 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 18/88 (20%) Query: 225 PARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRG 284 P PCQ E++++ +++S + L IP C++ G Y QC +G G Sbjct: 308 PGGLPCQNEMNRI-QKLSKGK---------SLLGAFIPRCNEEGYYKATQC----HGSTG 353 Query: 285 ECWCV----NPNTGKLIQGAPTIRGDPE 308 +CWCV N G QGA + + E Sbjct: 354 QCWCVDKYGNELAGSRKQGAVSCEEEQE 381 >gi|93141003 testican 3 isoform 1 [Homo sapiens] Length = 433 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 16/81 (19%) Query: 229 PCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWC 288 PCQ EL + +R +L + +IP CD+ G Y QC +G G+CWC Sbjct: 313 PCQTELSNIQKRQGVKKLLGQ----------YIPLCDEDGYYKPTQC----HGSVGQCWC 358 Query: 289 VNPNTGKLIQGAPTIRGDPEC 309 V+ G + G+ I G +C Sbjct: 359 VD-RYGNEVMGS-RINGVADC 377 >gi|93141001 testican 3 isoform 2 [Homo sapiens] Length = 436 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 16/81 (19%) Query: 229 PCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWC 288 PCQ EL + +R +L + +IP CD+ G Y QC +G G+CWC Sbjct: 316 PCQTELSNIQKRQGVKKLLGQ----------YIPLCDEDGYYKPTQC----HGSVGQCWC 361 Query: 289 VNPNTGKLIQGAPTIRGDPEC 309 V+ G + G+ I G +C Sbjct: 362 VD-RYGNEVMGS-RINGVADC 380 >gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] Length = 357 Score = 40.8 bits (94), Expect = 0.002 Identities = 27/73 (36%), Positives = 30/73 (41%), Gaps = 19/73 (26%) Query: 44 RCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGV 103 RCPP P R A PP P A + GC CC VCAR GE+C Sbjct: 34 RCPPQCPGRCPAT--PPTCAPGVRAVL--------------DGCSCCLVCARQRGESCSD 77 Query: 104 YTPRCGQ--GLRC 114 P C + GL C Sbjct: 78 LEP-CDESSGLYC 89 >gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] Length = 1036 Score = 40.8 bits (94), Expect = 0.002 Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 39/126 (30%) Query: 17 LLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARM 76 L+ LL LLLLL + G RA V C PC + C P P + V V Sbjct: 17 LVSLLGLLLLLARS-----GTRALV---CLPCDESK---CEEPRNCPGSIVQGV------ 59 Query: 77 PCAELVREPGCGCCSVCARLEGEAC----GVYTPRCGQGLRCYPHPGSELPLQALVMGE- 131 CGCC CA E+C G+Y C +GLRC P PL + E Sbjct: 60 ----------CGCCYTCASQRNESCGGTFGIY-GTCDRGLRCVIRP----PLNGDSLTEY 104 Query: 132 --GTCE 135 G CE Sbjct: 105 EAGVCE 110 >gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] Length = 457 Score = 40.8 bits (94), Expect = 0.002 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 261 IPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEAR 320 IP C+ G Y+ QC + G CWCV PN G+ I G P C NE+ R Sbjct: 110 IPECNDDGTYSQVQC----HSYTGYCWCVTPN-GRPISGTAVAHKTPRCPGSVNEKLPQR 164 Score = 40.0 bits (92), Expect = 0.003 Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 261 IPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPEC 309 IP C GLY QC S G CWCV +TG+ I G T P+C Sbjct: 248 IPECAHGGLYKPVQCHPST----GYCWCVLVDTGRPIPGTSTRYEQPKC 292 >gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens] Length = 666 Score = 40.4 bits (93), Expect = 0.002 Identities = 22/31 (70%), Positives = 22/31 (70%), Gaps = 2/31 (6%) Query: 8 PALPLPPPPLLPLLPLLLLLLGASGGGGGAR 38 P P PPPPLLPLLPLLLLLL G GAR Sbjct: 24 PPPPPPPPPLLPLLPLLLLLL--LGAAEGAR 52 Score = 35.0 bits (79), Expect = 0.091 Identities = 20/35 (57%), Positives = 22/35 (62%), Gaps = 4/35 (11%) Query: 3 PRVGCPALPLPPPPLLPLLP----LLLLLLGASGG 33 P + P P PPPP PLLP LLLLLLGA+ G Sbjct: 16 PALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEG 50 >gi|39812378 RAN binding protein 9 [Homo sapiens] Length = 729 Score = 40.0 bits (92), Expect = 0.003 Identities = 49/158 (31%), Positives = 56/158 (35%), Gaps = 36/158 (22%) Query: 12 LPPPPLLPLLPLLLLLL------------------GASGGGGGARAEVLFRCPPCTPERL 53 L PPP L P+ ++L GA G G GA A L PP P Sbjct: 19 LSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPA 78 Query: 54 AACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLR 113 A PPP PP A+ A A P A PG A G A G TP G Sbjct: 79 TAAPPPPPPPPPPPASAAAPASGPPA----PPG------LAAGPGPAGGAPTPALVAGSS 128 Query: 114 C---YPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQ 148 +PH S L Q E ++R Y A EQ Sbjct: 129 AAAPFPHGDSALNEQ-----EKELQRRLKRLYPAVDEQ 161 Score = 29.6 bits (65), Expect = 3.8 Identities = 25/71 (35%), Positives = 26/71 (36%), Gaps = 14/71 (19%) Query: 8 PALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAP-PAA 66 PA PPPP P P ASG PP P A GP AP PA Sbjct: 77 PATAAPPPPPPPPPPPASAAAPASG-------------PPAPPGLAAGPGPAGGAPTPAL 123 Query: 67 VAAVAGGARMP 77 VA + A P Sbjct: 124 VAGSSAAAPFP 134 >gi|78190498 secreted modular calcium-binding protein 1 isoform 1 [Homo sapiens] Length = 435 Score = 40.0 bits (92), Expect = 0.003 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 14/80 (17%) Query: 230 CQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCV 289 C QE LE ++ P E + IP C GLY QC S G CWCV Sbjct: 227 CDQERQSALEEA-------QQNPREGIV---IPECAPGGLYKPVQCHQST----GYCWCV 272 Query: 290 NPNTGKLIQGAPTIRGDPEC 309 +TG+ + G T P C Sbjct: 273 LVDTGRPLPGTSTRYVMPSC 292 Score = 35.4 bits (80), Expect = 0.070 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 16/83 (19%) Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286 ++ C+ E Q LE+ + P E ++ +P C + G + QC + G C Sbjct: 92 QSKCRLERAQALEQA---KKPQE--------AVFVPECGEDGSFTQVQC----HTYTGYC 136 Query: 287 WCVNPNTGKLIQGAPTIRGDPEC 309 WCV P+ GK I G+ P C Sbjct: 137 WCVTPD-GKPISGSSVQNKTPVC 158 >gi|11545873 secreted modular calcium-binding protein 1 isoform 2 [Homo sapiens] Length = 434 Score = 40.0 bits (92), Expect = 0.003 Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 14/80 (17%) Query: 230 CQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCV 289 C QE LE ++ P E + IP C GLY QC S G CWCV Sbjct: 227 CDQERQSALEEA-------QQNPREGIV---IPECAPGGLYKPVQCHQST----GYCWCV 272 Query: 290 NPNTGKLIQGAPTIRGDPEC 309 +TG+ + G T P C Sbjct: 273 LVDTGRPLPGTSTRYVMPSC 292 Score = 35.4 bits (80), Expect = 0.070 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 16/83 (19%) Query: 227 RTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGEC 286 ++ C+ E Q LE+ + P E ++ +P C + G + QC + G C Sbjct: 92 QSKCRLERAQALEQA---KKPQE--------AVFVPECGEDGSFTQVQC----HTYTGYC 136 Query: 287 WCVNPNTGKLIQGAPTIRGDPEC 309 WCV P+ GK I G+ P C Sbjct: 137 WCVTPD-GKPISGSSVQNKTPVC 158 >gi|169218303 PREDICTED: hypothetical protein [Homo sapiens] Length = 421 Score = 39.7 bits (91), Expect = 0.004 Identities = 35/104 (33%), Positives = 45/104 (43%), Gaps = 14/104 (13%) Query: 41 VLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEA 100 VLF+ C+P + A A + + GA C L GCGCCS RL Sbjct: 283 VLFQAVRCSPVGVGA------ASGCQMLTWSVGAAPGCQMLAW--GCGCCS---RLSDAH 331 Query: 101 CGVYTPRCGQGLRCYPHPGSELP-LQALVMGEGTCEKRRDAEYG 143 GV+ Q LRC P +P Q L G G+C + DA +G Sbjct: 332 LGVWV--LLQALRCSPGCVGAIPGYQMLTWGCGSCSRLSDAHFG 373 >gi|22129776 HtrA serine peptidase 3 [Homo sapiens] Length = 453 Score = 39.3 bits (90), Expect = 0.005 Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 53 LAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEAC-GVYTPRCGQG 111 LA PP AP A V+ C C CC VCA EGE C G CG+ Sbjct: 14 LALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGGPLDSPCGES 73 Query: 112 LRC 114 L C Sbjct: 74 LEC 76 >gi|68448544 CD74 antigen isoform a [Homo sapiens] Length = 296 Score = 38.9 bits (89), Expect = 0.006 Identities = 26/78 (33%), Positives = 33/78 (42%), Gaps = 19/78 (24%) Query: 215 LEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQ 274 LE+ PP T CQ+E+ + P H S P CD++G Y Q Sbjct: 198 LEQKPTDAPPKVLTKCQEEVSHI--------------PAVHPGSFR-PKCDENGNYLPLQ 242 Query: 275 CKMSLNGQRGECWCVNPN 292 C S+ G CWCV PN Sbjct: 243 CYGSI----GYCWCVFPN 256 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.140 0.451 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,748,461 Number of Sequences: 37866 Number of extensions: 1057831 Number of successful extensions: 6932 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 79 Number of HSP's successfully gapped in prelim test: 214 Number of HSP's that attempted gapping in prelim test: 6267 Number of HSP's gapped (non-prelim): 688 length of query: 328 length of database: 18,247,518 effective HSP length: 103 effective length of query: 225 effective length of database: 14,347,320 effective search space: 3228147000 effective search space used: 3228147000 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.