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Search of human proteins with 55750053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55750053 atrophin-1 [Homo sapiens]
(1190 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55750053 atrophin-1 [Homo sapiens] 2481 0.0
gi|55750041 atrophin-1 [Homo sapiens] 2481 0.0
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 709 0.0
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 709 0.0
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 709 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 162 1e-39
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 155 3e-37
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 129 2e-29
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 125 2e-28
gi|160707881 formin 2 [Homo sapiens] 124 5e-28
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 122 2e-27
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 119 1e-26
gi|47132519 Ras association and pleckstrin homology domains 1 is... 119 2e-26
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 117 7e-26
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 117 7e-26
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 117 7e-26
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 117 7e-26
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 116 1e-25
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 115 2e-25
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 114 6e-25
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 111 5e-24
gi|150170670 piccolo isoform 2 [Homo sapiens] 108 4e-23
gi|150378539 piccolo isoform 1 [Homo sapiens] 108 4e-23
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 107 5e-23
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 102 2e-21
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 102 2e-21
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 102 3e-21
gi|112421108 capicua homolog [Homo sapiens] 101 5e-21
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 100 8e-21
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 100 8e-21
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 2481 bits (6429), Expect = 0.0
Identities = 1190/1190 (100%), Positives = 1190/1190 (100%)
Query: 1 MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE 60
MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE
Sbjct: 1 MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE 60
Query: 61 EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD 120
EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD
Sbjct: 61 EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD 120
Query: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPE 180
PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPE
Sbjct: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPE 180
Query: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGA 240
ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGA
Sbjct: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGA 240
Query: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN 300
ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN
Sbjct: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN 300
Query: 301 LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP 360
LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP
Sbjct: 301 LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP 360
Query: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420
PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420
Query: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH 480
SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH 480
Query: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660
FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG
Sbjct: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660
Query: 661 SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP
Sbjct: 661 SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Query: 721 LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARS 780
LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARS
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARS 780
Query: 781 DLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVK 840
DLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVK
Sbjct: 781 DLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVK 840
Query: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
Query: 901 NHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPL 960
NHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPL
Sbjct: 901 NHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPL 960
Query: 961 HGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER 1020
HGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER
Sbjct: 961 HGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER 1020
Query: 1021 LAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLI 1080
LAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLI
Sbjct: 1021 LAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLI 1080
Query: 1081 DPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQL 1140
DPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQL
Sbjct: 1081 DPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQL 1140
Query: 1141 QAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190
QAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL
Sbjct: 1141 QAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 2481 bits (6429), Expect = 0.0
Identities = 1190/1190 (100%), Positives = 1190/1190 (100%)
Query: 1 MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE 60
MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE
Sbjct: 1 MKTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVE 60
Query: 61 EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD 120
EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD
Sbjct: 61 EASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSD 120
Query: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPE 180
PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPE
Sbjct: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPE 180
Query: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGA 240
ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGA
Sbjct: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGA 240
Query: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN 300
ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN
Sbjct: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN 300
Query: 301 LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP 360
LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP
Sbjct: 301 LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP 360
Query: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420
PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420
Query: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH 480
SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH
Sbjct: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH 480
Query: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660
FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG
Sbjct: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660
Query: 661 SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP
Sbjct: 661 SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPP 720
Query: 721 LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARS 780
LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARS
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARS 780
Query: 781 DLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVK 840
DLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVK
Sbjct: 781 DLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVK 840
Query: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNR 900
Query: 901 NHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPL 960
NHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPL
Sbjct: 901 NHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPL 960
Query: 961 HGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER 1020
HGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER
Sbjct: 961 HGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERERLALAAGPALRPDMSYAER 1020
Query: 1021 LAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLI 1080
LAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLI
Sbjct: 1021 LAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLI 1080
Query: 1081 DPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQL 1140
DPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQL
Sbjct: 1081 DPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQL 1140
Query: 1141 QAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190
QAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL
Sbjct: 1141 QAMHAQSAELQRLALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 709 bits (1830), Expect = 0.0
Identities = 451/937 (48%), Positives = 531/937 (56%), Gaps = 126/937 (13%)
Query: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
+P++P P +++SA L AQP L +P + PPG + PT P+P
Sbjct: 158 SPSIPSPQDNESDSDSSAQQQMLQAQPPA--LQAPTGVTPAPSSAPPGTPQLPTPGPTP- 214
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
S+ PP P +S + + A ++ + P PH P P
Sbjct: 215 ------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP-- 266
Query: 418 LSVSNQPPKYT------QPSLPSQA---VWSQGPPPPPPY--GRLLANSNAHPGP----- 461
S PP QPS PS A + QGPP P G LL HPGP
Sbjct: 267 ---SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ----HPGPPQPFG 319
Query: 462 FPP--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519
PP S G P + + H Q Q Q QQ ++Q PP P A PH
Sbjct: 320 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPH-- 373
Query: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGP-AHLPPPH--SQVSYSQAGPNGPPVSSSSNSSS 576
+ P + P P P AH PPH +S PP + SS
Sbjct: 374 ------------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 421
Query: 577 STSQGSYPCSHPSPSQ-GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG 635
ST P +HP P Q PQ P P P + P G +
Sbjct: 422 STHHP--PSAHPPPLQLMPQSQPLPSSP-------------------AQPPGLTQSQNLP 460
Query: 636 PPPYGKRAPSPGAYKTATPPGYK-----PGSPPSFRTGTPPGYRGTS-PPAGPGTFKPGS 689
PPP P G ++ A P + PG PP TPP TS PPAGPGT
Sbjct: 461 PPPASH--PPTGLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPAGPGTS---- 511
Query: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
P A SG A S PL QIK+E ++ E PESP PP RSPSP
Sbjct: 512 ---AQPPCSGAAASG------GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562
Query: 750 PPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQ 809
P VVD PSHASQSARF KHLDRG+NSCAR+DLYF+PL GSKLAKKR + +EK +REAEQ
Sbjct: 563 EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQ 622
Query: 810 RAREEKEREREREREKEREREKERELERSVKL---AQEGRAPVECPSL-GPVPHRPPFE- 864
+AREE+ERE+E+E+E+ERERE+ERE ER+ K A EGR + P L GP RP FE
Sbjct: 623 KAREEREREKEKEKEREREREREREAERAAKASSSAHEGR--LSDPQLSGPGHMRPSFEP 680
Query: 865 PGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALY 924
P + +A VPPY+GPDTPALRTLSEYARPHVMSP NRNHPFY+PL DP LL Y++P LY
Sbjct: 681 PPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDP-LLAYHMPGLY 739
Query: 925 SSDPAARE--------REREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG 976
+ DP RE RERE RER+LR+R+KPGFEVKP EL+PLH P ++ F RH
Sbjct: 740 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANP-MEHFARHSA 798
Query: 977 LALQPGPPGLHPF-PFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALG 1035
L + P G HPF FHP L PLERERLAL AGP LRP+MSY +RLAAER HAER+A+L
Sbjct: 799 LTIPP-TAGPHPFASFHPGLNPLERERLAL-AGPQLRPEMSYPDRLAAERIHAERMASLT 856
Query: 1036 NDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASAS-VHPLIDPLASGSHLTRIPY 1094
+DPLARLQM NVTPHHHQHSHIHSHLHLHQQD +H SA VHPL+DPL +G HL R PY
Sbjct: 857 SDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPY 916
Query: 1095 PAGTLPNPLLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRL 1153
P GTLPNPLL P HE+E+LRH +F PY RDLP ++ PMSAAHQLQAMHAQSAELQRL
Sbjct: 917 PPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRL 976
Query: 1154 ALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190
A+E QQWLH H +H LP+QEDYYS LKKE DK L
Sbjct: 977 AME-QQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1012
Score = 219 bits (559), Expect = 9e-57
Identities = 199/583 (34%), Positives = 260/583 (44%), Gaps = 103/583 (17%)
Query: 1 MKTRQNKDSMS-MRSGRKKEAPGP-------REELRSRGRASPGGVSTSSSDGKAEKSRQ 52
M+TR+++ SMS +RSGRKK+ P E++RS GR SP STSS+D KAE ++
Sbjct: 18 MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 77
Query: 53 TAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLD--SLDG 110
+AKK + E +S K NK+ R + S++E + + KKTKT QE+ RP SPS+ + S D
Sbjct: 78 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDS 136
Query: 111 RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARP---YHPPPLFPP 167
RS+ND+GSSDP+DIDQDNRSTSPSI SP E+DSDSS+ A+P P + P
Sbjct: 137 RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA 196
Query: 168 SPQPPDSTPRQPEASFEPH-----PSVTPTGYHAPMEP-------PTSRMFQA------- 208
P TP+ P P P +PT AP +P P + + QA
Sbjct: 197 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR 256
Query: 209 -----PPGAPPPHPQLYP-GGTGGVLSG-----PPMGPKG-GGAASSVGGPNGGKQHPPP 256
PP P PHP L P G+ G S PP+ +G G S GP QHP P
Sbjct: 257 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL--LQHPGP 314
Query: 257 TTPISVSSSGASGAPP--TKPPTT--------PVGGGNLPSAPPPANFPHVTPNLPPPPA 306
P + + G P T P P L S PP P LPP P
Sbjct: 315 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-----LPPAPL 369
Query: 307 LRP-LNNASASP----PGLGAQPLPGHL--PSPHAMGQGMGGLPPGPEKGPTLAPSPHSL 359
P + +P P A P HL PSP +M LPP P P + S H
Sbjct: 370 AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN---ANLPPPPALKPLSSLSTHHP 426
Query: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSL- 418
P SA PP++ S S+ A + S + P PAS PPT L
Sbjct: 427 P----SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH----------PPTGLH 472
Query: 419 SVSNQPPKYTQPSLPSQAVWSQGPPP-PPPYGRLLANSNAHPGPF--PPSTGAQSTAHPP 475
V+ QPP P +P GPPP PP + A PG PP +GA ++
Sbjct: 473 QVAPQPPFAQHPFVPG------GPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI 526
Query: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Q +++ ++ + PPPP P P
Sbjct: 527 AGGSSCPLPTVQIKEEALDDAEEPE-------SPPPPPRSPSP 562
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 709 bits (1830), Expect = 0.0
Identities = 451/937 (48%), Positives = 531/937 (56%), Gaps = 126/937 (13%)
Query: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
+P++P P +++SA L AQP L +P + PPG + PT P+P
Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPA--LQAPTGVTPAPSSAPPGTPQLPTPGPTP- 768
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
S+ PP P +S + + A ++ + P PH P P
Sbjct: 769 ------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP-- 820
Query: 418 LSVSNQPPKYT------QPSLPSQA---VWSQGPPPPPPY--GRLLANSNAHPGP----- 461
S PP QPS PS A + QGPP P G LL HPGP
Sbjct: 821 ---SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ----HPGPPQPFG 873
Query: 462 FPP--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519
PP S G P + + H Q Q Q QQ ++Q PP P A PH
Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPH-- 927
Query: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGP-AHLPPPH--SQVSYSQAGPNGPPVSSSSNSSS 576
+ P + P P P AH PPH +S PP + SS
Sbjct: 928 ------------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975
Query: 577 STSQGSYPCSHPSPSQ-GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG 635
ST P +HP P Q PQ P P P + P G +
Sbjct: 976 STHHP--PSAHPPPLQLMPQSQPLPSSP-------------------AQPPGLTQSQNLP 1014
Query: 636 PPPYGKRAPSPGAYKTATPPGYK-----PGSPPSFRTGTPPGYRGTS-PPAGPGTFKPGS 689
PPP P G ++ A P + PG PP TPP TS PPAGPGT
Sbjct: 1015 PPPASH--PPTGLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPAGPGTS---- 1065
Query: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
P A SG A S PL QIK+E ++ E PESP PP RSPSP
Sbjct: 1066 ---AQPPCSGAAASG------GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 1116
Query: 750 PPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQ 809
P VVD PSHASQSARF KHLDRG+NSCAR+DLYF+PL GSKLAKKR + +EK +REAEQ
Sbjct: 1117 EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQ 1176
Query: 810 RAREEKEREREREREKEREREKERELERSVKL---AQEGRAPVECPSL-GPVPHRPPFE- 864
+AREE+ERE+E+E+E+ERERE+ERE ER+ K A EGR + P L GP RP FE
Sbjct: 1177 KAREEREREKEKEKEREREREREREAERAAKASSSAHEGR--LSDPQLSGPGHMRPSFEP 1234
Query: 865 PGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALY 924
P + +A VPPY+GPDTPALRTLSEYARPHVMSP NRNHPFY+PL DP LL Y++P LY
Sbjct: 1235 PPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDP-LLAYHMPGLY 1293
Query: 925 SSDPAARE--------REREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG 976
+ DP RE RERE RER+LR+R+KPGFEVKP EL+PLH P ++ F RH
Sbjct: 1294 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANP-MEHFARHSA 1352
Query: 977 LALQPGPPGLHPF-PFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALG 1035
L + P G HPF FHP L PLERERLAL AGP LRP+MSY +RLAAER HAER+A+L
Sbjct: 1353 LTIPP-TAGPHPFASFHPGLNPLERERLAL-AGPQLRPEMSYPDRLAAERIHAERMASLT 1410
Query: 1036 NDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASAS-VHPLIDPLASGSHLTRIPY 1094
+DPLARLQM NVTPHHHQHSHIHSHLHLHQQD +H SA VHPL+DPL +G HL R PY
Sbjct: 1411 SDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPY 1470
Query: 1095 PAGTLPNPLLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRL 1153
P GTLPNPLL P HE+E+LRH +F PY RDLP ++ PMSAAHQLQAMHAQSAELQRL
Sbjct: 1471 PPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRL 1530
Query: 1154 ALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190
A+E QQWLH H +H LP+QEDYYS LKKE DK L
Sbjct: 1531 AME-QQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1566
Score = 219 bits (559), Expect = 9e-57
Identities = 199/583 (34%), Positives = 260/583 (44%), Gaps = 103/583 (17%)
Query: 1 MKTRQNKDSMS-MRSGRKKEAPGP-------REELRSRGRASPGGVSTSSSDGKAEKSRQ 52
M+TR+++ SMS +RSGRKK+ P E++RS GR SP STSS+D KAE ++
Sbjct: 572 MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 631
Query: 53 TAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLD--SLDG 110
+AKK + E +S K NK+ R + S++E + + KKTKT QE+ RP SPS+ + S D
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDS 690
Query: 111 RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARP---YHPPPLFPP 167
RS+ND+GSSDP+DIDQDNRSTSPSI SP E+DSDSS+ A+P P + P
Sbjct: 691 RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA 750
Query: 168 SPQPPDSTPRQPEASFEPH-----PSVTPTGYHAPMEP-------PTSRMFQA------- 208
P TP+ P P P +PT AP +P P + + QA
Sbjct: 751 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR 810
Query: 209 -----PPGAPPPHPQLYP-GGTGGVLSG-----PPMGPKG-GGAASSVGGPNGGKQHPPP 256
PP P PHP L P G+ G S PP+ +G G S GP QHP P
Sbjct: 811 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL--LQHPGP 868
Query: 257 TTPISVSSSGASGAPP--TKPPTT--------PVGGGNLPSAPPPANFPHVTPNLPPPPA 306
P + + G P T P P L S PP P LPP P
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-----LPPAPL 923
Query: 307 LRP-LNNASASP----PGLGAQPLPGHL--PSPHAMGQGMGGLPPGPEKGPTLAPSPHSL 359
P + +P P A P HL PSP +M LPP P P + S H
Sbjct: 924 AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN---ANLPPPPALKPLSSLSTHHP 980
Query: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSL- 418
P SA PP++ S S+ A + S + P PAS PPT L
Sbjct: 981 P----SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH----------PPTGLH 1026
Query: 419 SVSNQPPKYTQPSLPSQAVWSQGPPP-PPPYGRLLANSNAHPGPF--PPSTGAQSTAHPP 475
V+ QPP P +P GPPP PP + A PG PP +GA ++
Sbjct: 1027 QVAPQPPFAQHPFVPG------GPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI 1080
Query: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Q +++ ++ + PPPP P P
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPE-------SPPPPPRSPSP 1116
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/33 (45%), Positives = 26/33 (78%), Gaps = 1/33 (3%)
Query: 807 AEQRAREEKEREREREREKERE-REKERELERS 838
A++ ++KE++R+R+R++ERE R+K RE E S
Sbjct: 3 ADKDKDKDKEKDRDRDRDREREKRDKARESENS 35
Score = 31.2 bits (69), Expect = 6.1
Identities = 9/38 (23%), Positives = 26/38 (68%)
Query: 814 EKEREREREREKEREREKERELERSVKLAQEGRAPVEC 851
+K++++++E++++R+R++ERE + ++ R C
Sbjct: 4 DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSC 41
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 709 bits (1830), Expect = 0.0
Identities = 451/937 (48%), Positives = 531/937 (56%), Gaps = 126/937 (13%)
Query: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
+P++P P +++SA L AQP L +P + PPG + PT P+P
Sbjct: 712 SPSIPSPQDNESDSDSSAQQQMLQAQPPA--LQAPTGVTPAPSSAPPGTPQLPTPGPTP- 768
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
S+ PP P +S + + A ++ + P PH P P
Sbjct: 769 ------SATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHP-- 820
Query: 418 LSVSNQPPKYT------QPSLPSQA---VWSQGPPPPPPY--GRLLANSNAHPGP----- 461
S PP QPS PS A + QGPP P G LL HPGP
Sbjct: 821 ---SPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ----HPGPPQPFG 873
Query: 462 FPP--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL 519
PP S G P + + H Q Q Q QQ ++Q PP P A PH
Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPL----PPAPLAMPH-- 927
Query: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGP-AHLPPPH--SQVSYSQAGPNGPPVSSSSNSSS 576
+ P + P P P AH PPH +S PP + SS
Sbjct: 928 ------------IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975
Query: 577 STSQGSYPCSHPSPSQ-GPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG 635
ST P +HP P Q PQ P P P + P G +
Sbjct: 976 STHHP--PSAHPPPLQLMPQSQPLPSSP-------------------AQPPGLTQSQNLP 1014
Query: 636 PPPYGKRAPSPGAYKTATPPGYK-----PGSPPSFRTGTPPGYRGTS-PPAGPGTFKPGS 689
PPP P G ++ A P + PG PP TPP TS PPAGPGT
Sbjct: 1015 PPPASH--PPTGLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPPAGPGTS---- 1065
Query: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749
P A SG A S PL QIK+E ++ E PESP PP RSPSP
Sbjct: 1066 ---AQPPCSGAAASG------GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 1116
Query: 750 PPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQ 809
P VVD PSHASQSARF KHLDRG+NSCAR+DLYF+PL GSKLAKKR + +EK +REAEQ
Sbjct: 1117 EPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQ 1176
Query: 810 RAREEKEREREREREKEREREKERELERSVKL---AQEGRAPVECPSL-GPVPHRPPFE- 864
+AREE+ERE+E+E+E+ERERE+ERE ER+ K A EGR + P L GP RP FE
Sbjct: 1177 KAREEREREKEKEKEREREREREREAERAAKASSSAHEGR--LSDPQLSGPGHMRPSFEP 1234
Query: 865 PGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALY 924
P + +A VPPY+GPDTPALRTLSEYARPHVMSP NRNHPFY+PL DP LL Y++P LY
Sbjct: 1235 PPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDP-LLAYHMPGLY 1293
Query: 925 SSDPAARE--------REREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG 976
+ DP RE RERE RER+LR+R+KPGFEVKP EL+PLH P ++ F RH
Sbjct: 1294 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANP-MEHFARHSA 1352
Query: 977 LALQPGPPGLHPF-PFHPSLGPLERERLALAAGPALRPDMSYAERLAAERQHAERVAALG 1035
L + P G HPF FHP L PLERERLAL AGP LRP+MSY +RLAAER HAER+A+L
Sbjct: 1353 LTIPP-TAGPHPFASFHPGLNPLERERLAL-AGPQLRPEMSYPDRLAAERIHAERMASLT 1410
Query: 1036 NDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDAIHAASAS-VHPLIDPLASGSHLTRIPY 1094
+DPLARLQM NVTPHHHQHSHIHSHLHLHQQD +H SA VHPL+DPL +G HL R PY
Sbjct: 1411 SDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPY 1470
Query: 1095 PAGTLPNPLLPHPLHENEVLRHQLFAAPY-RDLPASLSAPMSAAHQLQAMHAQSAELQRL 1153
P GTLPNPLL P HE+E+LRH +F PY RDLP ++ PMSAAHQLQAMHAQSAELQRL
Sbjct: 1471 PPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRL 1530
Query: 1154 ALEQQQWLHAHHPLHSVPLPAQEDYYSHLKKESDKPL 1190
A+E QQWLH H +H LP+QEDYYS LKKE DK L
Sbjct: 1531 AME-QQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL 1566
Score = 219 bits (559), Expect = 9e-57
Identities = 199/583 (34%), Positives = 260/583 (44%), Gaps = 103/583 (17%)
Query: 1 MKTRQNKDSMS-MRSGRKKEAPGP-------REELRSRGRASPGGVSTSSSDGKAEKSRQ 52
M+TR+++ SMS +RSGRKK+ P E++RS GR SP STSS+D KAE ++
Sbjct: 572 MRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKK 631
Query: 53 TAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLD--SLDG 110
+AKK + E +S K NK+ R + S++E + + KKTKT QE+ RP SPS+ + S D
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKT-QEISRPNSPSEGEGESSDS 690
Query: 111 RSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARP---YHPPPLFPP 167
RS+ND+GSSDP+DIDQDNRSTSPSI SP E+DSDSS+ A+P P + P
Sbjct: 691 RSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPA 750
Query: 168 SPQPPDSTPRQPEASFEPH-----PSVTPTGYHAPMEP-------PTSRMFQA------- 208
P TP+ P P P +PT AP +P P + + QA
Sbjct: 751 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR 810
Query: 209 -----PPGAPPPHPQLYP-GGTGGVLSG-----PPMGPKG-GGAASSVGGPNGGKQHPPP 256
PP P PHP L P G+ G S PP+ +G G S GP QHP P
Sbjct: 811 PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL--LQHPGP 868
Query: 257 TTPISVSSSGASGAPP--TKPPTT--------PVGGGNLPSAPPPANFPHVTPNLPPPPA 306
P + + G P T P P L S PP P LPP P
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-----LPPAPL 923
Query: 307 LRP-LNNASASP----PGLGAQPLPGHL--PSPHAMGQGMGGLPPGPEKGPTLAPSPHSL 359
P + +P P A P HL PSP +M LPP P P + S H
Sbjct: 924 AMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN---ANLPPPPALKPLSSLSTHHP 980
Query: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSL- 418
P SA PP++ S S+ A + S + P PAS PPT L
Sbjct: 981 P----SAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASH----------PPTGLH 1026
Query: 419 SVSNQPPKYTQPSLPSQAVWSQGPPP-PPPYGRLLANSNAHPGPF--PPSTGAQSTAHPP 475
V+ QPP P +P GPPP PP + A PG PP +GA ++
Sbjct: 1027 QVAPQPPFAQHPFVPG------GPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSI 1080
Query: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Q +++ ++ + PPPP P P
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPE-------SPPPPPRSPSP 1116
Score = 32.7 bits (73), Expect = 2.1
Identities = 15/33 (45%), Positives = 26/33 (78%), Gaps = 1/33 (3%)
Query: 807 AEQRAREEKEREREREREKERE-REKERELERS 838
A++ ++KE++R+R+R++ERE R+K RE E S
Sbjct: 3 ADKDKDKDKEKDRDRDRDREREKRDKARESENS 35
Score = 31.2 bits (69), Expect = 6.1
Identities = 9/38 (23%), Positives = 26/38 (68%)
Query: 814 EKEREREREREKEREREKERELERSVKLAQEGRAPVEC 851
+K++++++E++++R+R++ERE + ++ R C
Sbjct: 4 DKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSC 41
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 162 bits (411), Expect = 1e-39
Identities = 206/724 (28%), Positives = 269/724 (37%), Gaps = 130/724 (17%)
Query: 89 KTKTEQELPRPQSPSDLDSLDGRSLND---DGSSDPRDIDQDNRSTSPSIYSPGSVE--N 143
K+ LP +P +DG S +S P++ ++ S + S G++
Sbjct: 732 KSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLA 791
Query: 144 DSDSSSGLSQGPARPYHPPPLFPPSPQPPD---STPRQP-EASFEPHPSV-------TPT 192
DS S G+S P P P P S+P P EASF P S+ +P
Sbjct: 792 DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851
Query: 193 GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252
H+P P +P GAP P + P GV P P + ++ P G
Sbjct: 852 TTHSPTPP-------SPKGAPTP-SAVTPLSPKGVTLPPKETPT--PSVVNLPFPKEGPA 901
Query: 253 HPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPP------- 305
P P ++S + +S P K TP G +P++P P P PP P
Sbjct: 902 TPAPKQAPALSMTSSS---PKKARATPAPKG-IPASPSPKGAPTPPAATPPSPKGGPATP 957
Query: 306 ----ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLP- 360
A P SP G A P P P+P A PP P+ GP PSP P
Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA------ATPPSPKGGPA-TPSPKGAPT 1010
Query: 361 PASSSAPAP---PMRFPYSSSSSSSAAASSSSSSSSSSASPFP------ASQALPSYPHS 411
P + + P+P P P+ +S+ AA+ S S +A+P P + LPS P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKG 1069
Query: 412 FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-----FPPST 466
P SL + PP T PS GP P P G + + P P PP
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKG------GPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123
Query: 467 GAQST--AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSS 524
GA +T A PP G + PPP GA P
Sbjct: 1124 GAPTTPAATPP-------------------------SPKGGLATPPPKGAPTTPA----- 1153
Query: 525 HHAHPYAMSPSLGSLRPYPPGPAHLP---PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG 581
A P SP G P P G P PP + + P G P + ++ S
Sbjct: 1154 --ATP--PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG-- 1207
Query: 582 SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641
+ PSP P P PP P ++ + T A++P K P PPP G
Sbjct: 1208 --GLATPSPKGAPT-TPAATPPSPKGGLATPSPKGAPTTPAATPPSPK-GGPATPPPKG- 1262
Query: 642 RAPSPGAYKTATPPGYKPG--SPPSFRTGTPPGYRGTSPPAGPGTFKP-GSPTVGPGPLP 698
AP+P A ATPP K G +PP P SP GP T P G+PT P
Sbjct: 1263 -APTPPA---ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT--PPAAT 1316
Query: 699 PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES---PVPPARSPSPPPKVVD 755
P P G P PPP AP + P ++ K P TP S P P+ P P
Sbjct: 1317 PPSPKGSPGTPPPKGAP-TPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA- 1374
Query: 756 VPSH 759
PSH
Sbjct: 1375 TPSH 1378
Score = 137 bits (346), Expect = 5e-32
Identities = 204/792 (25%), Positives = 286/792 (36%), Gaps = 139/792 (17%)
Query: 155 PARPYHPPP-----LFPPSPQ----PPDSTPRQPEASFE-PHPSVTPTGYHA-PMEPPTS 203
P P PP L PSP+ P +TP P+ P P PT A P P
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254
Query: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGP-----------PMGPKGGGAASSVGGPNGGKQ 252
P GAP P P GG+ + P P PKGG A S P G
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS----PPKGAP 1310
Query: 253 HPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN 312
PP TP S G+ G PP K TP P+ PP+ P TP LP A P +
Sbjct: 1311 TPPAATP--PSPKGSPGTPPPKGAPTP------PAVTPPS--PKGTPTLP---ATTPSSK 1357
Query: 313 ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR 372
+ P P P H G M PP P++GP + PSP P + + P P +
Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAM--TPPSPKRGPAI-PSPKGDPTSPAVIPLSPKK 1414
Query: 373 FPYSSSSSSSAAASSSSSSSSSSASPF-----PASQAL---PSYPHSFPPPTSLSVSNQP 424
P + + AA S + + +P PA+ A P+ P S PT +V+ P
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT--P 1472
Query: 425 PKYTQPSLPSQAVWS----QGPPPPPPYGR--LLANSNAHPGPFPPSTGAQSTAHPPVST 478
P +P P Q S + P P P G L A + P P + ++ P +T
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 479 HHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG----GSSHHAHPYAMSP 534
++ ++ P A P P E S + P A++P
Sbjct: 1533 -----LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Query: 535 SLGSLRPYP-----------------PGPAHLPPPHSQVSYSQAGPNG----PPVSSSSN 573
S P P P P + PP + + P G PPV+ SS
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSL 1647
Query: 574 SSSSTSQGSYPCSHPSP-SQGPQGAPYPFPP--VPTVTTSSATLSTVIATVAS--SPAGY 628
S TS S C + Q +G P P + V + A ST I T + P
Sbjct: 1648 KDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTK 1707
Query: 629 KTA--SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG-------------TPPGY 673
K++ SPP P + S G T P P S +T PP
Sbjct: 1708 KSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPES 1767
Query: 674 RGTSPPAGPGTFK----PGSPTVGPGPLPPAG----PSGLPSLPPP----PAAPASGPPL 721
+ ++P K P S +V P PP PS +P+LPP P++P G L
Sbjct: 1768 KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP--GLVL 1825
Query: 722 SATQIKQEPAEEYE----TPESPVP---PARS---PSPPPKVVDVPSHASQSARFNKHLD 771
+ PA+E E P P+ P +S P PK +P + + +
Sbjct: 1826 ESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNN 1885
Query: 772 RGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREK 831
+G + + SD LE D + ++A+ A E + E + ++ R +K
Sbjct: 1886 KGSGTESDSDESVPELE-------EQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKK 1938
Query: 832 ERELERSVKLAQ 843
R+ + L Q
Sbjct: 1939 ARKAMSKLGLRQ 1950
Score = 136 bits (342), Expect = 1e-31
Identities = 198/820 (24%), Positives = 273/820 (33%), Gaps = 120/820 (14%)
Query: 30 RGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKK 89
+G +P V+ S G ++T + V PK + + + + S +++PKK
Sbjct: 862 KGAPTPSAVTPLSPKGVTLPPKETPTPS-VVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920
Query: 90 TK-TEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSS 148
+ T P SPS G+ P + P+ SP ++
Sbjct: 921 ARATPAPKGIPASPSP-----------KGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 149 SGLSQG-PARPYH-----PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPT 202
+G PA P PP PPSP+ +TP P+ + P P+ +P P
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP-SPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 203 SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPM------GPKGGGAASSVGG---------- 246
+ PP A PP P+ P T P PKGG A S+ G
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 247 -PNGG------KQHPPPTTPISVSSSGASGAPPTK-PPTTPVGGGNLP----SAPPPANF 294
P GG K P P S G PP K PTTP P + PPP
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 295 PHVTPNLPPPP----ALRPLNNASASPPGLGAQPLPG-HLPSPHAMGQGMGGLPPGPEKG 349
P PP P A P A +P P G PSP PP P KG
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP-KG 1207
Query: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYP 409
PSP P ++ P P + S + +++ S P + P+ P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 410 HSFPPPTSLSVSNQPPKYT-QPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-----FP 463
+ PP ++ P K P++ + GP PP G + P P P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 464 PSTGA-----------QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPP 512
P GA + T P +T ++ H G PP
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 513 G-----AFPHPLEGGSSHHAHPY--------------AMSPSLGSLRPYPPGPAHLPPPH 553
A P P +S P A +PS G L P PA P
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP----PAVTPVSL 1443
Query: 554 SQVSYSQAGPNGPPVSSSSNSSSSTS-QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSA 612
+ + A GP SS + + P P+P Q + P +
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503
Query: 613 TLSTVIAT----VASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT-PPGYKPGSP----- 662
TL VI + V ++P+ + P K+ P+ A K A PP SP
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563
Query: 663 ---PSFRTGTPPGYRGTSPPA-GPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASG 718
P TP +SPPA P T+K G+P+ +PPA S P P P PA
Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYK-GAPSPKELLIPPAVTSPSPKEAPTP--PAVT 1620
Query: 719 PPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPS 758
PP P + TP P P P + D P+
Sbjct: 1621 PP--------SPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Score = 107 bits (267), Expect = 7e-23
Identities = 167/690 (24%), Positives = 234/690 (33%), Gaps = 136/690 (19%)
Query: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASF------EPHP-------SVTPTGYHAPMEPPT 202
A P + P S P P PEA+ EP P +P G ++
Sbjct: 565 AAPKNSPSFQSTSSSP--EIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIK 622
Query: 203 SRMFQAPPGAPP--------PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP--NGGKQ 252
+ + P A P P +P + P KG ++ P G
Sbjct: 623 TDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVS 682
Query: 253 HPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANF----------PHV----- 297
P P+ + T P P N P AP P N P +
Sbjct: 683 LAPKNHPVKEGTL-------TTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP 735
Query: 298 TPNLPP---PP------------ALRPL-----------NNASASPPGLGAQPLPGHLPS 331
+P+LPP PP AL P+ + ASA+ G PS
Sbjct: 736 SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS 795
Query: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
P + P +KG + P + P + S+P P+ + +S S S S +
Sbjct: 796 PLGVSVSPQTKRPPTKKG---SAGPDT-PIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851
Query: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP---- 447
++ S +P P+ + P+ P + P + V+ P + PS+ + +GP P P
Sbjct: 852 TTHSPTP-PSPKGAPT-PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 448 ------YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQ 501
A + P P S + PP +T +
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT--------------PPSPKGGPA 955
Query: 502 QHHGNSGPPPPGAFPHPLEGGSSHHA-----HPYAMSPSLGSLRPYPPGPAHLPPPHSQV 556
P PP A P +GG + + P A +P P P P P P
Sbjct: 956 TPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP---P 1012
Query: 557 SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP--FPPVPTVTTSSATL 614
+ + P G P ++ +ST + P PSP P P P P P T S
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATP---PSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 615 STVIATVASSPAGYKTASPPGP-----PPYGKRAPSPGAYKTATPPGYKPG--SPPSFRT 667
++ +P A+PP P P K AP P A ATPP K G +PP
Sbjct: 1070 GPATPSLKGAPTP-PAATPPSPKGGPATPSPKGAPMPPA---ATPPSPKGGLATPPHKGA 1125
Query: 668 GTPPGYRGTSPPAGPGTFKP-GSPTVGPGPLPPAGPSGLPSLPP--PPAAPASGPP---- 720
T P SP G T P G+PT P PP+ GL + PP P PA+ PP
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184
Query: 721 -LSATQIKQEPAEEYETPESPVPPARSPSP 749
L+ K P TP SP +PSP
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSP 1214
Score = 100 bits (248), Expect = 1e-20
Identities = 188/719 (26%), Positives = 243/719 (33%), Gaps = 160/719 (22%)
Query: 137 SPGSVEN-DSDSSSGLSQGPARPYHPP---------PLFPPSPQPPD----------STP 176
S G + N + S + L P P P P+ PP P P D P
Sbjct: 468 SSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFP 527
Query: 177 RQPE-----ASFEPHP-SVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSG 230
Q + AS E P S G +P + QA P P S
Sbjct: 528 TQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQS--------TSSS 579
Query: 231 P--PMGPKGGGAASSVGGPNG-GKQHPPPTTPISVSSSGA-----------SGAPPTKPP 276
P P+ P+ A S+G P GK T+P+ V+SS + S P K
Sbjct: 580 PEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSS 639
Query: 277 --TTPVGGGNLPSAPPPANFPHV-----------TPNLPPPPALRPLNNA--SASPPGLG 321
T V L SA P P +P L +L P N+ + L
Sbjct: 640 LITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP 699
Query: 322 AQPLPGH----LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377
P PSP + L PE P PSP SLPPA + PP
Sbjct: 700 LVPTASENCPVAPSPQNTCAPLATLVLAPEI-PKSVPSP-SLPPAGT----PPGTKKVDG 753
Query: 378 SSSSSAAASSSSS-----SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
S +SA A +SS + S AS +S+ +Y P P +SVS Q +
Sbjct: 754 ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR------ 807
Query: 433 PSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP--STGAQSTAHPPVSTHHHHHQQQQQQQ 490
P S GP P G L + + F P S Q + P +TH
Sbjct: 808 PPTKKGSAGPDTP--IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH----------- 854
Query: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP-PGPAHL 549
+ PP P P P + +SP +L P P P+ +
Sbjct: 855 ---------------SPTPPSPKGAPTP--------SAVTPLSPKGVTLPPKETPTPSVV 891
Query: 550 PPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP---FPPVPT 606
P + + P P S ++SS ++ + S P+GAP P PP P
Sbjct: 892 NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK 951
Query: 607 ---VTTSSATLSTVIATVASSP-AGYKTASPPGPP----------------PYGKRAPSP 646
T S T A SP G T SP G P P K AP+P
Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Query: 647 GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGT--FKPGSPTVGPGPLP-PAGPS 703
A +P G +P TPP SP P G+PT LP P G
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
Query: 704 GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE---SPVPPARSPSPPPKVVDVPSH 759
PSL P PA+ PP K PA TP +P+PPA +P P + P H
Sbjct: 1072 ATPSLKGAPTPPAATPPSP----KGGPA----TPSPKGAPMPPAATPPSPKGGLATPPH 1122
Score = 69.7 bits (169), Expect = 2e-11
Identities = 170/713 (23%), Positives = 240/713 (33%), Gaps = 148/713 (20%)
Query: 92 TEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGL 151
TEQELP+PQ+ + + + S + ++ PG
Sbjct: 12 TEQELPQPQAETAVLPMSSA-----------------LSVTAALGQPG------------ 42
Query: 152 SQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPS-VTPTGYHAPMEPPTSRMFQAPP 210
P PPP P Q P S Q AS P PS + T P P +S P
Sbjct: 43 ------PTLPPPCSPAPQQCPLSAANQ--ASPFPSPSTIASTPLEVPF-PQSSSGTALPL 93
Query: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV------SS 264
G P P P L GPP+ P AS + P K P + P+++ S
Sbjct: 94 GTAPEAPTFLPN-----LIGPPISPAALALASPMIAPT-LKGTPSSSAPLALVALAPHSV 147
Query: 265 SGASGAPP---TKPPTTPV---GGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPP 318
+S PP T PP+ V G SAP + P N P + P + SPP
Sbjct: 148 QKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVV-PNPKGTPSPP 206
Query: 319 GLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSS 378
+ +P H +P A Q +A P + P + + +P ++ +
Sbjct: 207 CI-VSTVPYHCVTPMASIQS------------GVASLPQTTPTTTLAIASPQVK----DT 249
Query: 379 SSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP--SQA 436
+ SS S + S S P PP +LS+S Q SLP + +
Sbjct: 250 TISSVLISPQNPGSLSLKGP-------------VSPPAALSLSTQ-------SLPVVTSS 289
Query: 437 VWSQGPPPPPPYGRLLANSNA--HPGPFPP-----STGAQSTAHPPVSTHHHHHQQQQQQ 489
+ GP PP + L + A H F TG + + P V T H
Sbjct: 290 QKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGAS 349
Query: 490 QQQQQQQQQQQQQHHGNSGPPPPGAFPHPL----------------EGGSSHHAHPYAMS 533
Q+ + P AFP GS + A +++S
Sbjct: 350 YPSQRSVIPPLPSRN-EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408
Query: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN--SSSSTSQGSYPCSHPSPS 591
P+ + P + P +Q+ S G V++ ++ +T+ C P S
Sbjct: 409 PTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMS 468
Query: 592 QGPQGAPYPFPPVPTVTTSSATL--STVIATVASSPAGYKTASPPGPPPYG-KRAPSPGA 648
GP P P V A ST +AT P SPP P P K PS
Sbjct: 469 SGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIP-----VSPPLPDPEDLKNLPSSVL 523
Query: 649 YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708
K T + + P+ G P PA G PTV PL A P PS
Sbjct: 524 VKFPTQKDLQ--TVPASLEGAP------FSPAQAGLTTKKDPTV--LPLVQAAPKNSPSF 573
Query: 709 PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
++P AT K+ E P+P + S + V S AS
Sbjct: 574 QSTSSSPEIPLSPEATLAKKSLGE-------PLPIGKPASSMTSPLGVNSSAS 619
Score = 63.5 bits (153), Expect = 1e-09
Identities = 138/620 (22%), Positives = 205/620 (33%), Gaps = 106/620 (17%)
Query: 18 KEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEIS 77
K AP P + +P +T+ S K + ++K+ A+TP S
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388
Query: 78 ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYS 137
+PK T + P SP + + +G++ P D +P +
Sbjct: 1389 PKRGPAIPSPKGDPTSPAVI-PLSPKKAPATP---VTREGAATPSKGD-----LTPPAVT 1439
Query: 138 PGSVENDSDSSSGLSQGPARPYHP-----PPLFPPSPQPPDSTPRQPEASFEPHPS-VTP 191
P S++ + ++S GPA P P + PPSP+ P + P+Q S P + TP
Sbjct: 1440 PVSLKK-APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA-PKQVATSSSPKKAPATP 1497
Query: 192 TGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGK 251
APM PT P P P+ P P+ P + K
Sbjct: 1498 ----APMGAPTL------PAVIPSSPKEVPATPSS--RRDPIAPTATLLSKKTPATLAPK 1545
Query: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
+ P ++V S + A PT P P + ++ PPA P P P L
Sbjct: 1546 EALIPPA-MTVPSPKKTPAIPT-PKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL---- 1599
Query: 312 NASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGP------------TLAPSPHSL 359
PP + P P P+P A+ PP PEKGP + PS
Sbjct: 1600 ---LIPPAV-TSPSPKEAPTPPAV------TPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
Query: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS 419
P S ++ M +S A ++ +P P S + + P P T S
Sbjct: 1650 SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709
Query: 420 VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTH 479
+ PP PS + S+GP S P P P
Sbjct: 1710 SATSPPICPDPSAKN---GSKGP-----------LSTVAPAPLLP--------------- 1740
Query: 480 HHHHQQQQQQQQQQQQQQQQQQQHHGNSGP--PPPGAFPHPLEGGSSHHAHPYAMSPSLG 537
Q+ + + + H GP PP PL + P S S+
Sbjct: 1741 ---------VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV- 1790
Query: 538 SLRPYPP-----GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592
S P PP P+ +P + + + P S S + + P P P
Sbjct: 1791 SAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS 1850
Query: 593 GPQGAPYPFPPVPTVTTSSA 612
G G P+ V T SA
Sbjct: 1851 G--GVPFQSVLVNMPTPKSA 1868
Score = 45.1 bits (105), Expect = 4e-04
Identities = 134/546 (24%), Positives = 189/546 (34%), Gaps = 76/546 (13%)
Query: 299 PNLPPP----PALRPLNNASA-----SPPGLGAQPLPGHLP-SPHAMGQGMGGLPPGPEK 348
P LPPP P PL+ A+ SP + + PL P S +G P P
Sbjct: 43 PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF 102
Query: 349 GPTLAPSPHSLPPASSSAP--APPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP 406
P L P S + ++P AP ++ SSS+ + A + S SSA P + P
Sbjct: 103 LPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP 162
Query: 407 SYPHSFPPPT---SLSVSNQPPKYTQPSLPSQAVWS-QGPPPPPPYGRLLANSNAHPGPF 462
S + S ++ PK +PS+ V + +G P PP + P
Sbjct: 163 SVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMAS 222
Query: 463 PPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP-PPPGAFPHPLEG 521
S A P +T Q + Q GP PP A +
Sbjct: 223 IQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQS 282
Query: 522 GSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYS-----QAGPNG---PPVSSSSN 573
+ P+ P G +HL P H S Q GP+ P V + S
Sbjct: 283 LPVVTSSQKTAGPNTPPDFPISLG-SHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISV 341
Query: 574 SSSSTSQGSYPCSH----PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAG-- 627
SST SYP P PS+ + P P V S + I+++ SP+G
Sbjct: 342 DHSSTG-ASYPSQRSVIPPLPSRN-EVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSL 399
Query: 628 -YKTASPPGPPPYGKRAPSPGAYK----TATPPGYKPGSPPSFRTGTPPGYRGTSPPAGP 682
T+ P SP A A P G+ P T T A
Sbjct: 400 NVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPC-----TIAAAPT 454
Query: 683 GTFKPG---SPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES 739
TF+ SP + GP+ P+ +L P AP K+ + T
Sbjct: 455 TTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAP-----------KEPSTQVATTLRI 503
Query: 740 PVPPARSPSPPPK-VVDVPSHASQSARFNKHLDRGFNSCARSDLYFVP--LEGSKLAKKR 796
PV P P P P+ + ++PS S +F + DL VP LEG+ + +
Sbjct: 504 PVSP---PLPDPEDLKNLPS--SVLVKFP----------TQKDLQTVPASLEGAPFSPAQ 548
Query: 797 ADLVEK 802
A L K
Sbjct: 549 AGLTTK 554
Score = 43.5 bits (101), Expect = 0.001
Identities = 77/360 (21%), Positives = 126/360 (35%), Gaps = 73/360 (20%)
Query: 86 APKKTK---TEQELPRPQSPSDLDSLDGRSLND-DGSSDPRDIDQDNRSTSPS---IYSP 138
+PKKT T +E P S + S + + G+ P+++ TSPS +P
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616
Query: 139 GSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ---------PEAS------- 182
+V S + P PP+ P S + ++P P+AS
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676
Query: 183 ---------FEPHPSVTPTGYHAPMEPPTSRMFQA--PPGAPPPHPQLYPGGTGGVLSGP 231
P P TP + P ++ A PP P P + G ++
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736
Query: 232 PMGP---------KGGGAASSVGGPNGGKQHPPPTTPISVSS---------SGASGAPPT 273
P+ P KG A+ S GP + +TP++ ++ S + A P+
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKA-STPLTAAAFEKVLPKPESASVSAAPS 1795
Query: 274 KPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP--PGLGAQPLPGHLPS 331
P + P+ +P+ PP F +P L +PL A P + +P+ G +P
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
+ P+P S A P P + P + ++ S S S S
Sbjct: 1856 QSVL---------------VNMPTPKS---AGIPVPTPSAKQPVTKNNKGSGTESDSDES 1897
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 155 bits (391), Expect = 3e-37
Identities = 186/718 (25%), Positives = 258/718 (35%), Gaps = 86/718 (11%)
Query: 77 SESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIY 136
+ S + + P + E+ P + S GR+ G++ P + Q S
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA---SGTTRPGPLGQKGLRISAEET 141
Query: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFE-----PHPSVTP 191
++ S LS G R P PSP R A E P PS P
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPA---MARRSRAAGTEVGLPRPAPSARP 198
Query: 192 TGYHAPMEPPTSRMFQAPPGA---PPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
P E P + A + P P + P GG+ S +
Sbjct: 199 ---RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 249 GGKQHPPPTTPISVSSSGASGAPPTKPP-TTPVGGGNLPSAPPPANFPHVTPNLPPPPAL 307
G P P S G +PP TP P+ P ++ P TP+ P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS-PSGTKA 314
Query: 308 RPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA--PSPHSLPPASS- 364
RP+ PP A PLP LP + + PP P P+L PSP + PP+ +
Sbjct: 315 RPV-----PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369
Query: 365 -SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPT---SLSV 420
S PPM+ P S + S +S S A P P + + S PT + S
Sbjct: 370 PSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP-----GPFPPSTGAQSTAHP- 474
P+ TQ SL S + + PP PP L+ + P P + T HP
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL 489
Query: 475 -PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP-----------PGAFPHPLEGG 522
+S+ H Q + Q + PP P P PL+
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
Query: 523 SSHHAHPYAMSPSLGSLRPY--PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
S+ P+ +P + P PP P PPP + S + P PP +S S
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 581 GSYPCSHPSPSQGPQGA--PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPP 638
P + P P P A P PP P + + L+T ++ A + +P PPP
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS---PTVGPG 695
+PP P SPP+ +PP SP A P + P S P +
Sbjct: 670 --------------SPPVQAPFSPPA----SPP----VSPSATPPSQAPPSLAAPPLQVP 707
Query: 696 PLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKV 753
P PPA P PS PPP AP PPL+A ++ P+ P SP S +PPP+V
Sbjct: 708 PSPPASPPMSPSATPPPQAP---PPLAAPPLQVPPSPPASPPMSP-----SATPPPRV 757
Score = 139 bits (351), Expect = 1e-32
Identities = 219/840 (26%), Positives = 289/840 (34%), Gaps = 146/840 (17%)
Query: 16 RKKEAPGPREELRSRG--RASPGGVSTSSSDGKAEKSRQTAKKA---RVEEASTPKVNKQ 70
R K P+ S G R + G + S A +SR + R ++ P+ +
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 71 GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130
G + +S + T P RP + L RSL+ S
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLS---------------S 244
Query: 131 TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP-----LFPPSPQPP--DSTPRQPEASF 183
++ + SP S+ G + PA P P P L PP PP D+ P S
Sbjct: 245 SATPLSSPA---RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 184 EPHPSVTPTGYHA-PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAAS 242
P + +P+G A P+ PP + P PP P P P+ P A
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP---------LPLAPPSPSAPP 352
Query: 243 SVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH--VTPN 300
S+ PP TP S + + P PP+ PP PH +P+
Sbjct: 353 SLQ-----TLPSPPATPPSQAPPSMTTPPMQAPPSL--------QTIPPIQVPHSLTSPS 399
Query: 301 LPPPPALRPLNNASASPPGLGAQPLPG--------------HLPSPHAMGQGMGGLPP-- 344
L PP+ L++ A+ LG+ L L SP PP
Sbjct: 400 LQAPPSPLALSSLQATT-SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
Query: 345 GPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404
P P P SL PA S +P P + SS A+ S + SS P +Q+
Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS--LASHSPQAPLSSLIMPPLETQS 516
Query: 405 LPSYPHSFPPPTSLSV-------SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457
+ P PP SL+ S PP S P + PP P P A
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP-----CPLQA 571
Query: 458 HPGPF--PPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAF 515
P P PP S A PP Q Q PPP A
Sbjct: 572 PPSPLTTPPPETPSSIATPP---------PQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 516 PH----PLEGGSSHHAHPYAMSPSLGSLRPYPPGP--AHL------PPPHSQVSYSQAGP 563
P PL+ S A P +SP L + P P HL PPP V + P
Sbjct: 623 PXLALPPLQAPPSPPASP-PLSP-LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680
Query: 564 NGPPVSSSSNSSSST-------------SQGSYPCSHPSPSQGPQGAPY---------PF 601
PPVS S+ S S + P PS + PQ P P
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-PSPGAYKT-ATPPGYKP 659
PP + SAT + + ++P SPP P A P P A ATPP
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQAL 800
Query: 660 GSPPSFRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPL--PPAGPSGLPSLPPPPAAPA 716
SPP+ G P S P P T P +P V PL P P P+L P P
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Query: 717 SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNS 776
GP S + + A P P PP+RSPS D+ H+S + + L RG++S
Sbjct: 861 PGPDTSVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 916
Score = 122 bits (305), Expect = 3e-27
Identities = 170/639 (26%), Positives = 227/639 (35%), Gaps = 126/639 (19%)
Query: 73 SEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTS 132
S +S S T P + + PQ+P L SL L S P + S +
Sbjct: 474 SPAVSPLSSPLTIHPLQALSSLASHSPQAP--LSSLIMPPLETQSSLAPPSLQTPPASLT 531
Query: 133 -------PSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP--QPPDSTPRQPEASF 183
PS+ P + ++ + P P P PPSP PP P P +
Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP---PETPSSIA 588
Query: 184 EPHPSVTPTGYHAPME----PPTSRMFQAPPGAPP----PHPQLYPGGTGGVLSGPPMGP 235
P P P P++ PP S + PP APP P Q P + PP+ P
Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP----ASPPLSP 644
Query: 236 KGGGAASSVGGPNGGKQH-------PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288
A S PN H PPP+ P+ S PP PP +P SA
Sbjct: 645 L---ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-----PPASPPVSP-------SA 689
Query: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
PP+ P P+L PP P + ++ P A P P +P + +PP P
Sbjct: 690 TPPSQAP---PSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQVPPSPPA 743
Query: 349 GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSY 408
P ++PS P APP++ P S +S + + + A P QALPS
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803
Query: 409 PHSFP------PPTSLSVS--NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG 460
P SFP P SL +S PP P L + + Q PP PP L A
Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL--QVPPSPPASPTLQAPRR---- 857
Query: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
PP+ G ++ P T PPPP P
Sbjct: 858 --PPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPSSTL 892
Query: 521 GGSSHHAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576
G H + + + LR Y GP A PPP +++ ++ +
Sbjct: 893 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL--------------AACHPA 938
Query: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTASPPG 635
+ S+G P P +G GAP P+PP T S+ L T+ T S A PG
Sbjct: 939 AWSRGPAP---PLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGALDPG 994
Query: 636 PPP---YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
P P GK A GA G SP R G P
Sbjct: 995 PSPGTSGGKAAAGAGA-------GASSRSPKQARLGELP 1026
Score = 117 bits (294), Expect = 5e-26
Identities = 169/672 (25%), Positives = 224/672 (33%), Gaps = 87/672 (12%)
Query: 92 TEQELPRPQSPSDLDSLDGRSLNDDGSSDPRD--IDQDNRSTSPSIYSPGSVENDSDSSS 149
T L P SP L SL + + + R T S+ SP + S
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Query: 150 GLSQGPARPYHPP------PLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTS 203
L + P PP P P P P Q +S H P M P +
Sbjct: 456 PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS-SLIMPPLET 514
Query: 204 RMFQAPPG--APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPIS 261
+ APP PP P L+ PP+ A++ + P+ + PP P
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT----ASAPLTTPH--LETPPCPAPCP 568
Query: 262 VSSSGASGAPP----TKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP 317
+ APP T PP TP P PPA LP PP +P
Sbjct: 569 LQ------APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 318 PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP--------HSLPPASSSAPAP 369
P L PL PSP P P P PSP H L S P+P
Sbjct: 623 PXLALPPLQAP-PSP----------PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS-------FPPPTSLSVSN 422
P++ P+S +S + S++ S + + P Q PS P S PPP +
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 423 QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST-AHPPVSTHHH 481
PP PS P+ S PPP LLA P PP++ S A PP
Sbjct: 732 APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP------ 785
Query: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH--PLEGGSSHHAHPYAMSPSLGSL 539
Q + P PP +FP P +S P A P
Sbjct: 786 ------------PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP- 832
Query: 540 RPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST--SQGSYPCSHPSPSQGPQGA 597
P P PP S + P PP S S + P P PS+ P
Sbjct: 833 -PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
Query: 598 PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGY 657
P + ++S+ + + S P G ASPP P+ + A P +
Sbjct: 892 -LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950
Query: 658 K--PGSP----PSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
+ PG+P P+ G+ G GP + P + PGP P G SG +
Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP--GTSGGKAAAGA 1008
Query: 712 PAAPASGPPLSA 723
A +S P A
Sbjct: 1009 GAGASSRSPKQA 1020
Score = 95.1 bits (235), Expect = 3e-19
Identities = 179/686 (26%), Positives = 237/686 (34%), Gaps = 177/686 (25%)
Query: 209 PPGAPPPHPQLYPG-----GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263
PPG+P P P + P G G + P+ + GG +GG T P S
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG----IGG---------ATIPESAP 75
Query: 264 SSG---ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG- 319
+G ++G P + P G APP N P P P + + PG
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-------AKNTSPGPVSSPGRASGTTRPGP 128
Query: 320 LGAQPL------------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH---------- 357
LG + L P A+ G GP G PSP
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG---TPSPAMARRSRAAGT 185
Query: 358 --SLP-PASSSAPAPPMRFPYSSSSSSSAAASS-------------------SSSSSSSS 395
LP PA S+ P PP P S SS+S +++ +S S SSS
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 396 ASPF-------PASQALPSYP--HSFPPPTSLSVSNQPPKYTQP---------------- 430
A+P P+++ P P S P P L + +PP+ T P
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ-ALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 431 SLPSQAVWSQGPPPPPPYGRLLANSNAHPGP--------FPPSTGA----QSTAHPPVST 478
+ PS + P PPP + P P PPS A Q+ PP +
Sbjct: 305 ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Query: 479 HHHHHQQQQQQQQQQQQQQQQ----QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534
Q Q Q H S P A P PL SS A SP
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS--PSLQAPPSPL-ALSSLQATTSLGSP 421
Query: 535 SLGSLRPY--------------PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
+L + + P PA PP + + P PP+ +S S + S
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS--LSPAVSP 479
Query: 581 GSYPCS-HP------SPSQGPQG--APYPFPPV--------PTVTTSSATLST--VIATV 621
S P + HP S PQ + PP+ P++ T A+L+T +
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG 681
+ +P +TAS P P+ + P P PP PP TP P A
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPE----TPSSIATPPPQAP 595
Query: 682 PGTFKP---GSPTVGPGPL---PPAGPS--GLPSLPPPPAAPASGPPLS--ATQIKQEP- 730
P P G P+ PL PP P LP L PP+ PAS PPLS AT Q P
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS-PPLSPLATPSPQAPN 654
Query: 731 ---AEEYETPES--PVPPARSPSPPP 751
+ P S P PP ++P PP
Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPP 680
Score = 94.4 bits (233), Expect = 6e-19
Identities = 144/573 (25%), Positives = 199/573 (34%), Gaps = 75/573 (13%)
Query: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKP---PTTPVGGGNLPSAPPPANFPHVTPNLPP 303
P G + PPP TP ++ GA+GA KP +GG +P + P A
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 304 PPALRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGLPPGP--EKG------PTLAP 354
PA RP AS G A P P P + G+ G PGP +KG T+A
Sbjct: 89 NPASRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 355 SPHSLPPASSSAPAPPMRFPY--SSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
+ P S+ A R + + S A A S ++ + P PA A P P
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
Query: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
P + S S T+PS ++ S G P R L +S+A P P +G +
Sbjct: 205 PRKSVSSASEH--STTEPSPAARRRPSAGGGLQRPASRSL-SSSATPLSSPARSGPSARG 261
Query: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP--- 529
P H + + Q + Q ++ GP P G+ P
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 530 YAMSPSLGSLRPYPP--GPAHLPPPHSQVSYS----QAGPNGPPVSSSSNSSSSTSQGSY 583
A +P +L P PP P L PP S + P PP + + ++ Q
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP 381
Query: 584 PCSHPSPSQGPQGAPYP---FPPVP--------TVTTSSATLSTVIATVASSP------- 625
P Q P P PP P T + S TL + + SP
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
Query: 626 --AGYKTASPPGPPPYGK--RAPSPGAYKTATPPGYKPGSPP-------------SFRTG 668
++PP PP P+ +T+ P P S P S
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
P P + P S P L LPSL PPP AS PL+ ++
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA-PLTTPHLET 560
Query: 729 EPAE---EYETPESPV--PPARSPS----PPPK 752
P + P SP+ PP +PS PPP+
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/223 (27%), Positives = 77/223 (34%), Gaps = 20/223 (8%)
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG-----PPVSSSSNSSSSTSQGSY 583
P A +P L L P PPG PPP + + G G P + +T S
Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 584 PCSHPSPSQGPQGA-PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
P + P+ S G P PP + SSP + PG P G++
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PLGQK 132
Query: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
A +T K P + R TS P PGT SP +
Sbjct: 133 GLRISAEETVARG--KATEAPKRSALSAGARRDTSGPT-PGT---PSPAMARRSRAAGTE 186
Query: 703 SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745
GLP P P A P PP + A E+ T E P P AR
Sbjct: 187 VGLPR-PAPSARPR--PPTEGPRKSVSSASEHSTTE-PSPAAR 225
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 129 bits (324), Expect = 2e-29
Identities = 208/822 (25%), Positives = 286/822 (34%), Gaps = 153/822 (18%)
Query: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196
SPG +S P P PPPL PP P PP P P + P +T G +
Sbjct: 224 SPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWS 283
Query: 197 PMEPPT---SRMFQAPPGAPP-----PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
+ R APP PHP YP + P G + AA GP
Sbjct: 284 TLHGDAWGPERKGSAPPERQEQRHSLPHPYPYP---APAYTAHPPGHRLVPAAPPGPGPR 340
Query: 249 GGKQHPPPTTPISVSSSGASGAPPTKPP-----TTPVGGGNLPSAPPPANFPHVTPNLPP 303
P S G P T+PP + V + S+ PA P P
Sbjct: 341 ----------PPGAESHGC--LPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPS 388
Query: 304 -PPAL----RPLNNASASPPGL-GAQPLPG-----HLPSPHAMGQGMGGLPPG--PEKGP 350
PP L +++S+S GL G +P PG H +P G L P + P
Sbjct: 389 RPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKP 448
Query: 351 TL---APSPH-SLPPASSSAPAPP----MRFPYSSSSSSSAAASSSSSSSSSSASPF--- 399
L A +PH SLPP SS P PP +R P + A ++ F
Sbjct: 449 FLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGT 508
Query: 400 --PASQALPSYPHS----FPPPTSLSVSNQ-------PPKYTQPSLPSQAVWSQGPP--- 443
P A P PH PP + SV Q PP T S S + P
Sbjct: 509 EGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
Query: 444 ---PPPPYGRLLANSNAHPGPFPPSTGAQ---------STAHPPVSTHHHHHQQQQQQQQ 491
PPPPY LA S P P PPS + A PP H ++
Sbjct: 569 VSFPPPPY---LARS-IDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRR 624
Query: 492 QQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP 551
+ + + GP PP P PL P + P +G L P PP
Sbjct: 625 PESPRPRVSFPKTPEVGPGPP---PGPLSKA------PQPVPPGVGELPARGPRLFDFPP 675
Query: 552 PHSQVSYSQAG-----PNG-----PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQG---AP 598
+ + + P+G + S Q + P + P +P
Sbjct: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
Query: 599 YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP----GPPPYGKRAPSPGAYKTATP 654
+P PT T + ++T T ++ A + P PPP + P P + P
Sbjct: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
Query: 655 PGYKPG----SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP-----PAGPSGL 705
P P S S G YRGT + + PGPLP P PSG
Sbjct: 796 PPPSPASLLKSLASVLEGQKYCYRGTG----------AAVSTRPGPLPTTQYSPGPPSGA 845
Query: 706 PSLPPPPAAPAS--GPPLSATQIKQEP------AEEYETPESPVPPARSPSPPPKVVDVP 757
+LPP AAP++ P SA+ Q A E E PVP +P+ PP + +P
Sbjct: 846 TALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
Query: 758 SHASQS---ARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814
S+S ++ + RS P + A+ E++ A+ A+EE
Sbjct: 906 PARSESEVLEEISRACETLVERVGRSAT--DPADPVDTAEPADSGTERLLPPAQ--AKEE 961
Query: 815 KE---------REREREREKEREREKERELERSVKLAQEGRA 847
+ R++E +KE R + + + +EGRA
Sbjct: 962 AGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRA 1003
Score = 88.6 bits (218), Expect = 3e-17
Identities = 171/704 (24%), Positives = 228/704 (32%), Gaps = 140/704 (19%)
Query: 132 SPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTP 191
+P +P + +S G Q R P L+ Q +S EA+ H ++
Sbjct: 77 APGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRY 136
Query: 192 TGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP-------------KGG 238
G A + P R+ QA QL+ TG + P K
Sbjct: 137 GGSFAELGPRIGRLQQA---------QLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRN 187
Query: 239 GAASSVGGPNGGKQHPPPTTPISVSS-SGASGAPPTKPPTTPVGGGNLPSAPPPANFPHV 297
A G P PP P+ ++ SG SG P G N P P
Sbjct: 188 YGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLP 247
Query: 298 TPNL-----PPPPALRPLNNASASP------PGL--------------GAQP-------- 324
P L PPPP PL + SP PGL G+ P
Sbjct: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRH 307
Query: 325 -LPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA 383
LP P P PPG P P P PP + S P P S S
Sbjct: 308 SLPHPYPYP---APAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESR 364
Query: 384 AASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPK------YTQPSLPSQAV 437
S SS S A+ PS P P T+ S S+ P +P
Sbjct: 365 VQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADH 424
Query: 438 WSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497
+ +GRL ++++ PF GA P +T H +
Sbjct: 425 YQTPALEVSHHGRLGPSAHSSRKPF---LGA------PAATPHLSLPPGPSSPPPPPCPR 475
Query: 498 QQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH------PYAMSPSLGSLRPYPPGPAH--- 548
+ PPPP A+ L+G + A + G RP PP H
Sbjct: 476 LLR--------PPPPPAW---LKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREG 524
Query: 549 -LPPPHSQVSYSQAGPNGPPV-------SSSSNSSSSTSQGSYPCSHPSPSQGPQGA-PY 599
L PP S+ S + PP SS+SNS S +S + P S P P + P
Sbjct: 525 FLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPL 584
Query: 600 PFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP 659
P PP P L V T+A PA PP + G+++ P +
Sbjct: 585 PRPPSPAQNPQDPPL--VPLTLALPPA----------PPSSCHQNTSGSFRRPESPRPRV 632
Query: 660 GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGP 719
P + G PG PP GP + P G G LP GP L PP P
Sbjct: 633 SFPKTPEVG--PG-----PPPGPLSKAPQPVPPGVGELPARGPR-LFDFPPTPLEDQFEE 684
Query: 720 P----------------LSATQIKQEPAEEYETPESPVPPARSP 747
P L + K+E +++E +P PP + P
Sbjct: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEP 728
Score = 61.2 bits (147), Expect = 6e-09
Identities = 91/377 (24%), Positives = 132/377 (35%), Gaps = 78/377 (20%)
Query: 131 TSPSIYSPGSVENDSDSSSGLSQGPARP--YHPPPLFPPSPQPPDSTPRQPEASFEPH-P 187
T P+ +P + ++S+S S S PA P + PPP S P PR P + P P
Sbjct: 542 TPPTPPTPTTSSSNSNSGSH-SSSPAGPVSFPPPPYLARSIDP---LPRPPSPAQNPQDP 597
Query: 188 SVTPTGYHAPMEPP------TSRMFQAPPG-----APPPHPQLYPGGTGGVLSGPPMGPK 236
+ P P PP TS F+ P + P P++ PG G LS P
Sbjct: 598 PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVP 657
Query: 237 GGGAASSVGGPNGGKQHPPPTTPI----------------------------------SV 262
G GP + P TP+
Sbjct: 658 PGVGELPARGP---RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQ 714
Query: 263 SSSGASGAPPTKPP----TTPVGGGNLPSAPPPANFPHVTPNL------------PPPPA 306
+G + PP K P +P P+ PA T PPPA
Sbjct: 715 HEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPA 774
Query: 307 LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPE---KGPTLAPSPHSLP-PA 362
L P + PP QP P PSP ++ + + + G + +G A S P P
Sbjct: 775 LPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPT 834
Query: 363 SSSAPAPP---MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS 419
+ +P PP P +S++ S+ + S+SSSS S A P P ++
Sbjct: 835 TQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMT 894
Query: 420 VSNQPPKYTQPSLPSQA 436
+ PP + P S++
Sbjct: 895 PTQPPPPLSLPPARSES 911
Score = 57.8 bits (138), Expect = 6e-08
Identities = 155/706 (21%), Positives = 220/706 (31%), Gaps = 213/706 (30%)
Query: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP---- 354
P+ PP A P SAS +G PLP LP H G P PT P
Sbjct: 33 PHPPPRSAWLPGGRCSAS---IGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGK 89
Query: 355 --SPHSLPPASSSAPAPPMRFP-----YSSSSSSSAAA---------------------- 385
S H A PA P + Y S S A
Sbjct: 90 LESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGR 149
Query: 386 -------SSSSSSSSSSASPFPASQALPSYPH----------SFPPPTSLSVSNQPPKYT 428
+ + S A P + + + H PP + P
Sbjct: 150 LQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAE---PPVV 206
Query: 429 QPSLPSQAVWSQGPPPPPPYGRLLANSNAH-----------PGPFPPSTGAQSTAHPPV- 476
QP P+ G P G+ N+ P P PP PP+
Sbjct: 207 QPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLP 266
Query: 477 ----------------STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520
ST H +++ ++Q+Q+ +S P P +P+P
Sbjct: 267 GLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQR-----HSLPHP---YPYPAP 318
Query: 521 GGSSH---HAHPYAMSPSLGSLRPYPPG-------PAHLPP------------------- 551
++H H A P G P PPG PA PP
Sbjct: 319 AYTAHPPGHRLVPAAPPGPG---PRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVS 375
Query: 552 ---PHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV- 607
+ V Y+ + P G P +++S+SSSS+S P+P G GA + P V
Sbjct: 376 PAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNP--GIPGADHYQTPALEVS 433
Query: 608 ----------TTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAY-------- 649
++ L AT S ++ PP P P R P P A+
Sbjct: 434 HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRA 493
Query: 650 -------------------KTATPP---------------------GYKPGSPPSFRTGT 669
+ A PP + P +PP+ T +
Sbjct: 494 AREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSS 553
Query: 670 PPGYRG--TSPPAGPGTFKPG---SPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSAT 724
G +S PAGP +F P + ++ P P PP+ P+ P PP + PP +
Sbjct: 554 SNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPS-PAQNPQDPPLVPLTLALPPAPPS 612
Query: 725 QIKQEPAEEYETPESPVP-------PARSPSPPPKVVD------VPSHASQSARFNKHLD 771
Q + + PESP P P P PPP + P AR + D
Sbjct: 613 SCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFD 672
Query: 772 RGFNSCARSDLYFVPLEGSKLAKKRADLV----EKVRREAEQRARE 813
F D + P E L A+++ E +R+E EQ+ E
Sbjct: 673 --FPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHE 716
Score = 42.0 bits (97), Expect = 0.003
Identities = 47/195 (24%), Positives = 65/195 (33%), Gaps = 15/195 (7%)
Query: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPA 156
P+P SL D + +T+ + + + E + L P
Sbjct: 721 PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPP 780
Query: 157 RPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPH 216
PPP P P PP P P + + SV + T PG P P
Sbjct: 781 LAKFPPPSQPQPPPPP---PPSPASLLKSLASVLEGQKYC--YRGTGAAVSTRPG-PLPT 834
Query: 217 PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP 276
Q PG G + PP A S+ G P P ++ S+SG A +
Sbjct: 835 TQYSPGPPSGATALPPT----SAAPSAQGSP-----QPSASSSSQFSTSGGPWARERRAG 885
Query: 277 TTPVGGGNLPSAPPP 291
PV G P+ PPP
Sbjct: 886 EEPVPGPMTPTQPPP 900
Score = 35.4 bits (80), Expect = 0.33
Identities = 84/382 (21%), Positives = 106/382 (27%), Gaps = 110/382 (28%)
Query: 432 LPSQAVWSQGPPPPPPYGRLLANSNAH--------PGPFPPSTGAQSTAH-------PPV 476
L WS PP PPP L P P PPS G+ S+ H P
Sbjct: 22 LSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGS-SSGHPSKPYYAPGA 80
Query: 477 STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL 536
T H + + Q ++ P PG + + S H A
Sbjct: 81 PTPRPLHGKLESLHGCVQALLRE---------PAQPGLWEQLGQLYESEHDSEEATRCYH 131
Query: 537 GSLRPYPPGPAHLPPPHSQVSYSQA-----------GPNGPPVSSSSNSSSSTSQGSYPC 585
+LR Y A L P ++ +Q PP+ N + +Y
Sbjct: 132 SALR-YGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGA 190
Query: 586 SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPS 645
P P PVP S P G+ S
Sbjct: 191 KRGGPPVKRAAEPPVVQPVPPAALSG--------------------------PSGEEGLS 224
Query: 646 PGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGL 705
PG G + S +TG PPG PP P P P PP P L
Sbjct: 225 PG--------GKRRRGCNSEQTGLPPGLPLPPPPLPP-----------PPPPPPPPPPPL 265
Query: 706 PSLPPPPAAPASGPPL---------------SATQIKQE-------------PAEEYETP 737
P L P + P L SA +QE PA P
Sbjct: 266 PGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPP 325
Query: 738 ESPVPPARSPSPPPKVVDVPSH 759
+ PA P P P+ SH
Sbjct: 326 GHRLVPAAPPGPGPRPPGAESH 347
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 125 bits (315), Expect = 2e-28
Identities = 176/702 (25%), Positives = 240/702 (34%), Gaps = 164/702 (23%)
Query: 16 RKKEAPGPREELRSRG--RASPGGVSTSSSDGKAEKSRQTAKKA---RVEEASTPKVNKQ 70
R K P+ S G R + G + S A +SR + R ++ P+ +
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194
Query: 71 GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130
G + +S + T P RP + L RSL+ S
Sbjct: 195 GPRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLS---------------S 235
Query: 131 TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP-----LFPPSPQPP--DSTPRQPEASF 183
++ + SP S+ G + PA P P P L PP PP D+ P S
Sbjct: 236 SATPLSSPA---RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292
Query: 184 EPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG-----TGGVLSGPPMGPKGG 238
P + +P+ +P PP+ + +PP PP G T L PP+ P
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352
Query: 239 GAASSVGGPNGGKQHPPPTTP--ISVSSSGASGAPPTKPPTTPVGGGNLPSAP------- 289
PPP P +++ A +PP PP +P+ + P AP
Sbjct: 353 ---------------PPPQAPPALALPPLQAPPSPPASPPLSPLATPS-PQAPNALAVHL 396
Query: 290 ------PPANFPHVTPNLPP--PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341
PP + P P PP PP S +PP L A PL PSP A
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSPS 455
Query: 342 LPPGPEKGPTLAPSPHSL----PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397
P P+ P LA P L P A + PP++ A S +S +
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ------------ALPSPPASFPGQA 503
Query: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457
PF S +LP P + PPP + PP P L Q PP PP L A
Sbjct: 504 PFSPSASLPMSPLATPPPQA------PPVLAAPLL-------QVPPSPPASPTLQAPRR- 549
Query: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH 517
PP+ G ++ P T PPPP P
Sbjct: 550 -----PPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPS 581
Query: 518 PLEGGSSHHAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQVSYSQAGPNGPPVSSSSN 573
G H + + + LR Y GP A PPP +++ ++
Sbjct: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL--------------AAC 627
Query: 574 SSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTAS 632
++ S+G P P +G GAP P+PP T S+ L T+ T S A
Sbjct: 628 HPAAWSRGPAP---PLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGAL 683
Query: 633 PPGPPP---YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
PGP P GK A GA G SP R G P
Sbjct: 684 DPGPSPGTSGGKAAAGAGA-------GASSRSPKQARLGELP 718
Score = 116 bits (291), Expect = 1e-25
Identities = 166/655 (25%), Positives = 226/655 (34%), Gaps = 109/655 (16%)
Query: 155 PARPYHPPPLFPPSPQ---PPDSTPRQPEASF----------EPHPSVTPTGYHAPMEPP 201
P P PPP+ P + + + R+P A E P PT P P
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP--PA 87
Query: 202 TSRMFQAPPGA-PPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPI 260
+ R +APP P P PG G P+G KG ++ G P + +
Sbjct: 88 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147
Query: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL-PPPPALRPLNNASASPPG 319
S + + P P +P +A P P+ P PP P + S++
Sbjct: 148 SAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206
Query: 320 LGAQPLPG-----------HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA 368
+P P P+ ++ L GP+ +P + PA S P
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA--PAHPSQPK 264
Query: 369 P----PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
P +R P + AA + SSS A+P P++ PS P SL P
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS------APPSLQTLPSP 318
Query: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQ 484
P + PSQA S G P L + P PP + A PP+
Sbjct: 319 P----ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL-------- 366
Query: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544
PP P A P PL S A P +P+ +L +
Sbjct: 367 ----------------------QAPPSPPASP-PL----SPLATPSPQAPN--ALAVHLL 397
Query: 545 GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPV 604
PPP V + P PPVS S+ S + PS + P P P PP
Sbjct: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ--------APPSLAAPPLQVP-PSPPA 448
Query: 605 PTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPS 664
+ SAT ++P PP PP ATPP SPP+
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP-----------ALATPPLQALPSPPA 497
Query: 665 FRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPL 721
G P S P P T P +P V PL P P P+L P P GP
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 557
Query: 722 SATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNS 776
S + + A P P PP+RSPS D+ H+S + + L RG++S
Sbjct: 558 SVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 608
Score = 115 bits (287), Expect = 3e-25
Identities = 151/580 (26%), Positives = 202/580 (34%), Gaps = 65/580 (11%)
Query: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220
P P P+PP PR+ +S H + P+ P R A G P +
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPS-------PAARRRPSAGGGLQRPASRSL 233
Query: 221 PGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ------HPPPTTPISVSSSGASGAPPTK 274
+ S GP G + P+ K PP TP ++ A G +
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293
Query: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHA 334
P TP PSAPP + P LP PPA P + A+ S Q LPSP
Sbjct: 294 PLATPS-----PSAPPSPSAPPSLQTLPSPPATPP-SQATTSLGSPTLQATHSFLPSPPL 347
Query: 335 MGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSA-AASSSSSSSS 393
P P+ P LA P PP S PA P P ++ S + A + +
Sbjct: 348 SPLAT----PPPQAPPALALPPLQAPP---SPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 394 SSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453
S P P QA P P + PP +S S PP PSL + + Q PP PP A
Sbjct: 401 FSPPPSPPVQA-PFSPPASPP---VSPSATPPSQAPPSLAAPPL--QVPPSPP------A 448
Query: 454 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513
+ P PP A PP+ Q + Q + P PP
Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPL-----------QLAKPPPQAPPALATPPLQALPSPPA 497
Query: 514 AFPH--PLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
+FP P +S P A P P P PP S + P PP
Sbjct: 498 SFPGQAPFSPSASLPMSPLATPPPQAP--PVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 555
Query: 572 SNSSSST--SQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK 629
S S + P P PS+ P P + ++S+ + + S P G
Sbjct: 556 DTSVSGPRLTLALAPGPPPPPSRSPSST-LSGPDLAGHSSSATSTPEELRGYDSGPEGGA 614
Query: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYK--PGSP----PSFRTGTPPGYRGTSPPAGPG 683
ASPP P+ + A P ++ PG+P P+ G+ G GP
Sbjct: 615 AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE 674
Query: 684 TFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSA 723
+ P + PGP P G SG + A +S P A
Sbjct: 675 SATPAPGALDPGPSP--GTSGGKAAAGAGAGASSRSPKQA 712
Score = 112 bits (281), Expect = 2e-24
Identities = 148/525 (28%), Positives = 189/525 (36%), Gaps = 78/525 (14%)
Query: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA 306
P G + PPP TP ++ GA+GA KP GG A P P P
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG------GATIPESAPRAGPTRT 82
Query: 307 LRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGLPPGP--EKG------PTLAPSPH 357
RP AS G A P P P + G+ G PGP +KG T+A
Sbjct: 83 SRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138
Query: 358 SLPPASSSAPAPPMRFPYSSS--SSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPP 415
+ P S+ A R + + S A A S ++ + P PA A P P P
Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198
Query: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475
+ S S T+PS ++ S G P R L++S A P P +G + P
Sbjct: 199 SVSSASEHST--TEPSPAARRRPSAGGGLQRPASRSLSSS-ATPLSSPARSGPSARGTPR 255
Query: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535
H + + Q + Q PP A P SS A P SPS
Sbjct: 256 APAHPSQPKPKGLQALRPPQVT-----------PPRKDAAPALGPLSSSPLATP---SPS 301
Query: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQ 595
PP LP P P PP ++++ S T Q ++ PSP P
Sbjct: 302 APPSPSAPPSLQTLPSP----------PATPPSQATTSLGSPTLQATHSFL-PSPPLSPL 350
Query: 596 GAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-PSPGAYKTAT- 653
P P P + P SPP PP A PSP A
Sbjct: 351 ATPPPQAP----------------PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 654 ----PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS---PTVGPGPLPPAGPSGLP 706
P P SPP +PP SP A P + P S P + P PPA P P
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454
Query: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS-PSPP 750
S PPP AP PPL+A ++ P PP ++ PSPP
Sbjct: 455 SATPPPQAP---PPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 124 bits (311), Expect = 5e-28
Identities = 180/706 (25%), Positives = 234/706 (33%), Gaps = 126/706 (17%)
Query: 41 SSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQ 100
+ ++ ++ S K++ + + +G++ I + E +T +TK EL R
Sbjct: 641 AETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLE--QTIEDLRTKIA-ELERQY 697
Query: 101 SPSDLDSLDGRSLNDDGSSDPRDIDQDN-RSTSPSIYSPGSVENDSDSSSGLSQGPARPY 159
D + G ++G + D+ + R + +E S +S +G
Sbjct: 698 PALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTL 757
Query: 160 HPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQL 219
P P P P P+ F S+ + ++ + + Q+ PPP L
Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLL 817
Query: 220 YPGGTGGVLSGPPMGPKGGGAAS-----SVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274
+ G G S PP S S N PP P + SSS G
Sbjct: 818 WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVP 877
Query: 275 PPTTPVGGGNLPSAPPPANFPHVTP-----NLPPPPALRPLNNASASPPGLGAQPLPGH- 328
PP P+ G +P+ P A P P LPPPP PL A PP PLPG
Sbjct: 878 PPPPPLPGMTVPTLPSTA-IPQPPPLQGTEMLPPPPP--PLPGAGIPPP----PPLPGAG 930
Query: 329 -LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASS 387
LP P G G+PP P P P LP A P PP+
Sbjct: 931 ILPLPPLPG---AGIPPPPPLPGAAIPPPPPLPGAGIPLP-PPL---------------- 970
Query: 388 SSSSSSSSASPFPASQALPSYP---HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP 444
+ P P + P P PPP L + PP P LP + PPP
Sbjct: 971 -PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPPLPGAGI----PPP 1022
Query: 445 PPPYGRLLANSNAHPG----PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQ 500
PP G + PG P PP GA PP+
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP----------------------- 1059
Query: 501 QQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQ 560
G PPPP PL G P P G P P A +PPP
Sbjct: 1060 ----GAGIPPPP-----PLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGVGI 1107
Query: 561 AGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIAT 620
P PP+ + G+ P P P P PP+P V
Sbjct: 1108 PPP--PPLPGAGIPPPPPLPGA---GIPPPPPLPGAGIPPPPPLPRV------------G 1150
Query: 621 VASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPA 680
+ P PP PP G P P P P PP G PP PP
Sbjct: 1151 IPPPPPLPGAGIPPPPPLPGAGIPPP----PPLPGVGIPPPPPLPGVGIPP------PPP 1200
Query: 681 GPGTFKPGSPT-----VGPGPLPPAGPSGLPSLPPPPAAPASGPPL 721
PG P P + P P PP P G +PPPP P SGPPL
Sbjct: 1201 LPGAGIPPPPPLPGMGIPPAPAPPLPPPG-TGIPPPPLLPVSGPPL 1245
Score = 92.8 bits (229), Expect = 2e-18
Identities = 141/529 (26%), Positives = 174/529 (32%), Gaps = 126/529 (23%)
Query: 94 QELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRST-----------SPSIYSPGSVE 142
Q + +P P L L GS P I + +++ S +I SP +
Sbjct: 805 QSISQPPPPPSL--LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
Query: 143 NDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPT 202
SSS G P PP P P + P P + P + T P PP
Sbjct: 863 CTESSSSMPGLGMVPP-------PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 203 SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTT---- 258
PGA P P PG G+L PP+ G G P PPP
Sbjct: 916 -------PGAGIPPPPPLPGA--GILPLPPL--PGAGIPPPPPLPGAAIPPPPPLPGAGI 964
Query: 259 PISVSSSGASGAPPTK------PPTTPVGGGNLPSAPP--PANFPHVTP----NLPPPPA 306
P+ GA PP PP P+ G +P PP A P P +PPPP
Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP- 1023
Query: 307 LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSA 366
PL A PP PLPG P G G PP P G + P P P +
Sbjct: 1024 --PLPGAGIPPP----PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIP 1075
Query: 367 PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPH---SFPPPTSLSVSNQ 423
P PP+ + P P + P P PPP L +
Sbjct: 1076 PPPPL-----------------PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118
Query: 424 PPKYTQPSL---PSQAVWSQGPPPPPPYGRL-LANSNAHPG----PFPPSTGAQSTAHPP 475
PP P P + G PPPPP R+ + PG P PP GA PP
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Query: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG------AFPHPLEGGSSHHAHP 529
+ G PPPP P PL G P
Sbjct: 1179 LP---------------------------GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPP 1211
Query: 530 YAMSPSLGSLRPYPPGPA-HLPPPHSQVSYSQAGP-NGPPVSSSSNSSS 576
P +G PP PA LPPP + + P +GPP+ SS+
Sbjct: 1212 L---PGMG----IPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSST 1253
Score = 92.4 bits (228), Expect = 2e-18
Identities = 145/523 (27%), Positives = 179/523 (34%), Gaps = 116/523 (22%)
Query: 277 TTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASA------SPPGLGAQPLPGHLP 330
T+P G + + PP P P PP P + SP + Q L H P
Sbjct: 746 TSPTEEGGVLTLPPVDGLPG-RPPCPPGAESGPQTKFCSEISLIVSPRRISVQ-LDSHQP 803
Query: 331 SPHAMGQGMGGLPPGPEKGPTLAPS-PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS 389
+ Q + PP P + P S PP S S + +S S +++ +
Sbjct: 804 T-----QSISQPPPPPSLLWSAGQGQPGSQPPHSISTE-------FQTSHEHSVSSAFKN 851
Query: 390 SSSSSSASPFPASQALPSYPHSF---PPPTSLSVSNQPPKYTQPSLPSQAVWS----QG- 441
S + S P P +++ S P PPP L P T P+LPS A+ QG
Sbjct: 852 SCNIPSPPPLPCTESSSSMPGLGMVPPPPPPL------PGMTVPTLPSTAIPQPPPLQGT 905
Query: 442 ---PPPPPPY-GRLLANSNAHPG----PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
PPPPPP G + PG P PP GA PP+
Sbjct: 906 EMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP---------------- 949
Query: 494 QQQQQQQQQHHGNSGPPPP---GA---FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA 547
G + PPPP GA P PL G P P G P P A
Sbjct: 950 -----------GAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL---PGAGIPPPPPLPGA 995
Query: 548 HLPPPHSQVSYSQAG-PNGPPVSSSSNSSSSTSQGS-YPCSHPSPSQG-PQGAPYP---F 601
+PPP AG P PP+ + G+ P P P G P P P
Sbjct: 996 GIPPPPPLPG---AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1052
Query: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTA--TPPGYKP 659
PP P + A + P PP PP G P P A PP P
Sbjct: 1053 PPPPPLPG---------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1103
Query: 660 G-----SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714
G PP G PP PP PG P P + +PP P +PPPP
Sbjct: 1104 GVGIPPPPPLPGAGIPP------PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 715 PASG----PPLSATQIKQEPAEEYE--TPESPVPPARSPSPPP 751
P +G PPL I P P P+P P PPP
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
Score = 53.5 bits (127), Expect = 1e-06
Identities = 66/237 (27%), Positives = 84/237 (35%), Gaps = 46/237 (19%)
Query: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP------GAPP 214
PPP P + PP P P A P P + G P PP R+ PP G PP
Sbjct: 1109 PPPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPP--PPLPRVGIPPPPPLPGAGIPP 1164
Query: 215 PHPQLYPGG-------TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267
P P PG GV PP G G P G PPP + + + A
Sbjct: 1165 PPP--LPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA 1222
Query: 268 SGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG 327
PP PP T + PPP P + PP L + +++ P + G
Sbjct: 1223 ---PPLPPPGTGI--------PPPPLLP-----VSGPPLLPQVGSSTLPTP-----QVCG 1261
Query: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAA 384
LP P + G+ GL +KG P + P P R S SS +
Sbjct: 1262 FLPPP--LPSGLFGLGMNQDKGSRKQP----IEPCRPMKPLYWTRIQLHSKRDSSTS 1312
Score = 52.4 bits (124), Expect = 3e-06
Identities = 68/258 (26%), Positives = 89/258 (34%), Gaps = 28/258 (10%)
Query: 484 QQQQQQQQQQQQQQQQQQQHHGNSGP--PPPGAFPHPLEGGSSHHAHPYAMSPSLGS-LR 540
QQQQQQ Q Q QQQQQQQQ G P PP P P G+ + + PS G+
Sbjct: 207 QQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQP---GAFLGLDRFLLGPSGGAGEA 263
Query: 541 PYPPGPAHLPPPHSQVSYSQAG-PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPY 599
P P S + S A P P S + S P + P+ P +
Sbjct: 264 PGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAF 323
Query: 600 PFPPV-PTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYK 658
PFP P + A + T +P G P + AP +
Sbjct: 324 PFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPG-EEWAP-------------E 369
Query: 659 PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGP---GPLPPAGPSGLPSLPPPPAAP 715
G R G P P A PGSP P P P + + ++P
Sbjct: 370 VGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSP 429
Query: 716 ASGP---PLSATQIKQEP 730
P P + +IK+ P
Sbjct: 430 NHSPSQSPNQSPRIKRRP 447
Score = 47.8 bits (112), Expect = 6e-05
Identities = 65/275 (23%), Positives = 87/275 (31%), Gaps = 85/275 (30%)
Query: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544
QQQQQQQ Q Q QQQQQQ L+G A P A+S
Sbjct: 206 QQQQQQQLQLQLQQQQQQQQ--------------LQGAEEPAAPPTAVS----------- 240
Query: 545 GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPV 604
P P + + + GP G P
Sbjct: 241 -----PQPGAFLGLDRF-----------------------------LLGPSGGAGEAPGS 266
Query: 605 PTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPS 664
P + + LS + ++A+ P P P PSPG + P P +
Sbjct: 267 PDTEQALSALSDLPESLAAEP-----REPQQP-------PSPGGLPVSEAPSLPAAQPAA 314
Query: 665 FRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG--------PSGLPSLPPPPAAPA 716
+P P AGPG G+P G G G P G P P
Sbjct: 315 --KDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGE 372
Query: 717 SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
P ++ +EP EE + P++P + SP P
Sbjct: 373 DAP----QRLGEEPEEEAQGPDAPAAASLPGSPAP 403
Score = 35.8 bits (81), Expect = 0.25
Identities = 45/159 (28%), Positives = 53/159 (33%), Gaps = 36/159 (22%)
Query: 852 PSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAV 911
P LG VP PP PG V T+P P P L+ P PG P PL
Sbjct: 871 PGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG-AGIPPPPPLPGA 929
Query: 912 D----PGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGV---- 963
P L G +P P PG + P P G+
Sbjct: 930 GILPLPPLPGAGIP---PPPPL------------------PGAAIPPPPPLPGAGIPLPP 968
Query: 964 --PGPGLDPFPRHGGLALQPGPP----GLHPFPFHPSLG 996
PG G+ P P G + P PP G+ P P P G
Sbjct: 969 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007
Score = 32.0 bits (71), Expect = 3.6
Identities = 33/125 (26%), Positives = 46/125 (36%), Gaps = 32/125 (25%)
Query: 282 GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341
G P+APP A P P A L+ P G G G
Sbjct: 228 GAEEPAAPPTAVSPQ-------PGAFLGLDRFLLGPSG------------------GAGE 262
Query: 342 LPPGPEKGPTLAPSPHSLPPASSSAPAPPMR------FPYSSSSSSSAAASSSSSSSSSS 395
P P+ L+ + LP + ++ P P + P S + S AA ++ S SS+
Sbjct: 263 APGSPDTEQALS-ALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSST 321
Query: 396 ASPFP 400
A PFP
Sbjct: 322 AFPFP 326
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 122 bits (306), Expect = 2e-27
Identities = 147/533 (27%), Positives = 194/533 (36%), Gaps = 55/533 (10%)
Query: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTP---VGGGNLPSAPPPANFPHVTPNLPP 303
P G + PPP TP ++ GA+GA KP +GG +P + P A
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 304 PPALRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGLPPGP--EKG------PTLAP 354
PA RP AS G A P P P + G+ G PGP +KG T+A
Sbjct: 89 NPASRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
Query: 355 SPHSLPPASSSAPAPPMRFPYSSS--SSSSAAASSSSSSSSSSASPFPASQALPSYPHSF 412
+ P S+ A R + + S A A S ++ + P PA A P P
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
Query: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
P + S S T+PS ++ S G P R L++S A P P +G +
Sbjct: 205 PRKSVSSASEHST--TEPSPAARRRPSAGGGLQRPASRSLSSS-ATPLSSPARSGPSARG 261
Query: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP--PPPGAFPHPLEGGSSHHAHPY 530
P H + + Q + Q ++ GP P A P P S
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321
Query: 531 AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSH--- 587
+P SL P L PP S PP + S +++S + +H
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381
Query: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-PSP 646
PSP P P P P + P SPP PP A PSP
Sbjct: 382 PSPPLSPLATPPPQAP----------------PALALPPLQAPPSPPASPPLSPLATPSP 425
Query: 647 GAYKTAT-----PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS---PTVGPGPLP 698
A P P SPP +PP SP A P + P S P + P P
Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485
Query: 699 PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS-PSPP 750
PA P PS PPP AP PPL+A ++ P PP ++ PSPP
Sbjct: 486 PASPPMSPSATPPPQAP---PPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
Score = 117 bits (292), Expect = 8e-26
Identities = 167/649 (25%), Positives = 225/649 (34%), Gaps = 111/649 (17%)
Query: 209 PPGAPPPHPQLYPG-----GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263
PPG+P P P + P G G + P+ + GG +GG T P S
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG----IGGA---------TIPESAP 75
Query: 264 SSG---ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG- 319
+G ++G P + P G APP N P P P + + PG
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-------AKNTSPGPVSSPGRASGTTRPGP 128
Query: 320 LGAQPL------------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH---------- 357
LG + L P A+ G GP G PSP
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG---TPSPAMARRSRAAGT 185
Query: 358 --SLP-PASSSAPAPPMRFPYSSSSSSSAAASSSSSS------SSSSASPFPASQALPSY 408
LP PA S+ P PP P S SS+S +++ S S+ PAS++L S
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 409 --PHSFPPPTSLSVSNQPPKYTQPSLPS----QAVWSQGPPPP-----PPYGRLLANSNA 457
P S P + S P PS P QA+ PP P G L ++ A
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 458 HPGPFPPSTGAQSTAHPPV-STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFP 516
P P S QS A P + +T H Q + P PP P
Sbjct: 306 TPSP---SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPP 362
Query: 517 HP----LEGGSSHHAHPYAMSPSLGSLRPYPPG--PA-HLPPPHSQVSYSQAGPNGPPVS 569
L + H + SP L L PP PA LPP + S + P P +
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 422
Query: 570 SSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK 629
S + ++ + P P AP+ P P V+ S+ S ++A+ P
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482
Query: 630 TASPPGPPPYGKRAPSPGA--------YKTATPPGYKP---GSPPSFRTGTPPGYRGTSP 678
+ P PP P P A + A PP P +PP +PP
Sbjct: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 542
Query: 679 PAGPGTFKPGSPTVGPGPLPPA-----------GPSGLPSLPPPPAAPASGPPLSATQIK 727
P P P SP P P P P P+L P P GP S + +
Sbjct: 543 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 602
Query: 728 QEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNS 776
A P P PP+RSPS D+ H+S + + L RG++S
Sbjct: 603 LTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 647
Score = 116 bits (291), Expect = 1e-25
Identities = 180/720 (25%), Positives = 242/720 (33%), Gaps = 170/720 (23%)
Query: 16 RKKEAPGPREELRSRG--RASPGGVSTSSSDGKAEKSRQTAKKA---RVEEASTPKVNKQ 70
R K P+ S G R + G + S A +SR + R ++ P+ +
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
Query: 71 GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130
G + +S + T P RP + L RSL+ S
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLS---------------S 244
Query: 131 TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP-----LFPPSPQPP--DSTPRQPEASF 183
++ + SP S+ G + PA P P P L PP PP D+ P S
Sbjct: 245 SATPLSSPA---RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 184 EPHPSVTPTGYHAPMEPPT----------SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPM 233
P + +P+ PPT + P PP P P L PP
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ--TLPSPPA 359
Query: 234 GPKGGGAASSVGGPNGGKQH-------------PPPTTP--ISVSSSGASGAPPTKPPTT 278
P A +S+G P H PPP P +++ A +PP PP +
Sbjct: 360 TPPSQ-ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418
Query: 279 PVGGGNLPSAP-------------PPANFPHVTPNLPP--PPALRPLNNASASPPGLGAQ 323
P+ + P AP PP + P P PP PP S +PP L A
Sbjct: 419 PLATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477
Query: 324 PLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSL----PPASSSAPAPPMRFPYSSSS 379
PL PSP A P P+ P LA P L P A + PP++
Sbjct: 478 PLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ------- 529
Query: 380 SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS 439
A S +S +PF S +LP P + PPP + PP P L
Sbjct: 530 -----ALPSPPASFPGQAPFSPSASLPMSPLATPPPQA------PPVLAAPLL------- 571
Query: 440 QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499
Q PP PP L A PP+ G ++ P T
Sbjct: 572 QVPPSPPASPTLQAPRR------PPTPGPDTSVSGPRLT--------------------- 604
Query: 500 QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQ 555
PPPP P G H + + + LR Y GP A PPP ++
Sbjct: 605 --LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 662
Query: 556 VSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615
+ ++ ++ S+G P P +G GAP P+PP T S+ L
Sbjct: 663 L--------------AACHPAAWSRGPAP---PLAFRGAPGAPLPWPPA-TGPGSADGLC 704
Query: 616 TVIATVA-SSPAGYKTASPPGPPP---YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
T+ T S A PGP P GK A GA G SP R G P
Sbjct: 705 TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA-------GASSRSPKQARLGELP 757
Score = 42.4 bits (98), Expect = 0.003
Identities = 61/223 (27%), Positives = 77/223 (34%), Gaps = 20/223 (8%)
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG-----PPVSSSSNSSSSTSQGSY 583
P A +P L L P PPG PPP + + G G P + +T S
Sbjct: 17 PAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 584 PCSHPSPSQGPQGA-PYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
P + P+ S G P PP + SSP + PG P G++
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PLGQK 132
Query: 643 APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
A +T K P + R TS P PGT SP +
Sbjct: 133 GLRISAEETVARG--KATEAPKRSALSAGARRDTSGPT-PGT---PSPAMARRSRAAGTE 186
Query: 703 SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR 745
GLP P P A P PP + A E+ T E P P AR
Sbjct: 187 VGLPR-PAPSARPR--PPTEGPRKSVSSASEHSTTE-PSPAAR 225
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 119 bits (299), Expect = 1e-26
Identities = 159/551 (28%), Positives = 207/551 (37%), Gaps = 90/551 (16%)
Query: 221 PGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA--PPTKPPTT 278
P G+ + P G G A S +GG + P TP + ++ A GA P T
Sbjct: 1487 PTNIPGLGAAGPTGMFFGSAPSPMGGIS------PAMTPWNQGATPAYGAWSPSVGSGMT 1540
Query: 279 PVGGGNLPSAPPPAN--FPHVTPNLPPPPALRPLNNASASP--PGLGAQPLPGHLP-SPH 333
P G PSA A+ P +P P P P + +SP P G P + P SP
Sbjct: 1541 PGAAGFSPSAASDASGFSPGYSPAWSPTPG-SPGSPGPSSPYIPSPGGAMSPSYSPTSPA 1599
Query: 334 AMGQGMGGLPP-GPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392
+ GG P P PT SP P + S +P P P S S S ++ + S +S S
Sbjct: 1600 YEPRSPGGYTPQSPSYSPT---SPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPS 1656
Query: 393 SSSASPFPASQALPSYPHSFPP--PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGR 450
S SP S PSY + P PTS S S P Y+ P+ PS + P P Y
Sbjct: 1657 YSPTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-PTSPSYS------PTSPSYS- 1707
Query: 451 LLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
P PS S ++ P S + P
Sbjct: 1708 ----------PTSPSYSPTSPSYSPTSPSY---------------------------SPT 1730
Query: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSS 570
P P +S P + + S S P P++ P + SYS PN P S
Sbjct: 1731 SPSYSP------TSPSYSPTSPNYSPTSPNYTPTSPSYSP---TSPSYSPTSPNYTPTSP 1781
Query: 571 SSNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK 629
+ + +S + + P P SPS P Y P PT T SS + S SSP+ Y
Sbjct: 1782 NYSPTSPSYSPTSPSYSPTSPSYSPSSPRYT-PQSPTYTPSSPSYSP------SSPS-YS 1833
Query: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGT--FKP 687
SP P +PS Y T T P Y P SP + T P Y TSP P T + P
Sbjct: 1834 PTSPKYTPTSPSYSPSSPEY-TPTSPKYSPTSPKY--SPTSPKYSPTSPTYSPTTPKYSP 1890
Query: 688 GSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSP 747
SPT P P P+ P P + P S T P + SP P SP
Sbjct: 1891 TSPTYSPTS-PVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSP 1949
Query: 748 SPPPKVVDVPS 758
+ P + P+
Sbjct: 1950 TSPTYSLTSPA 1960
Score = 84.7 bits (208), Expect = 5e-16
Identities = 81/282 (28%), Positives = 120/282 (42%), Gaps = 32/282 (11%)
Query: 505 GNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPG------PAHLP--PPHSQV 556
G+ G P P + P GG+ ++ SP+ + P PG P++ P P +S
Sbjct: 1570 GSPGSPGPSSPYIPSPGGAMSPSY----SPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPT 1625
Query: 557 S--YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPVPTVTTSSAT 613
S YS PN P S S + +S + + P P SPS P Y P P+ + +S +
Sbjct: 1626 SPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-PTSPSYSPTSPS 1684
Query: 614 LSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSP------PSFRT 667
S + + + Y SP P +P+ +Y + T P Y P SP PS+ +
Sbjct: 1685 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY-SPTSPSYSPTSPSYSPTSPSY-S 1742
Query: 668 GTPPGYRGTSP---PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSAT 724
T P Y TSP P P ++ P SP+ P P P+ P P+ + P S T
Sbjct: 1743 PTSPNYSPTSPNYTPTSP-SYSPTSPSYSPTS-PNYTPTSPNYSPTSPSYSPTSPSYSPT 1800
Query: 725 QIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARF 766
P+ TP+SP SPS P PS++ S ++
Sbjct: 1801 SPSYSPSSPRYTPQSPTYTPSSPSYSP---SSPSYSPTSPKY 1839
Score = 81.6 bits (200), Expect = 4e-15
Identities = 121/481 (25%), Positives = 170/481 (35%), Gaps = 63/481 (13%)
Query: 132 SPSIYS---PGSV---ENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEP 185
SPS+ S PG+ + + +SG S G + + P P P SP P S+P P
Sbjct: 1532 SPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGP--SSPYIPSPGGAM 1589
Query: 186 HPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG 245
PS +PT +P P S P G P P P + P P
Sbjct: 1590 SPSYSPT---SPAYEPRS-----PGGYTPQSPSYSPTSPSYSPTSPSYSPT--------- 1632
Query: 246 GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP--PANFPHVTPNLPP 303
PN + P + S +S S P+ PT+P PS P P+ P P
Sbjct: 1633 SPN----YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1688
Query: 304 PPALRPLNNASASPPGLGAQPL-PGHLP-SPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361
P+ P + S SP P P + P SP P P PT SP P
Sbjct: 1689 SPSYSP-TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT---SPSYSPT 1744
Query: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP--PPTSLS 419
+ + +P P P S S S ++ + S +S + + SP S PSY + P PTS S
Sbjct: 1745 SPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSP-NYSPTSPSYSPTSPSYSPTSPS 1803
Query: 420 VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTH 479
S P+YT P ++ P P + ++ P PS S + P S
Sbjct: 1804 YSPSSPRYT----PQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPK 1859
Query: 480 HHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL 539
+ + + P P P + + + SP+
Sbjct: 1860 YSPTSPKYSPTSPKY-------------SPTSPTYSPTTPKYSPTSPTY----SPTSPVY 1902
Query: 540 RPYPPGPAHLPPPHSQVS--YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGA 597
P P + P +S S YS P P S ++ S TS G P S P +
Sbjct: 1903 TPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAIS 1962
Query: 598 P 598
P
Sbjct: 1963 P 1963
Score = 73.6 bits (179), Expect = 1e-12
Identities = 102/389 (26%), Positives = 135/389 (34%), Gaps = 47/389 (12%)
Query: 99 PQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARP 158
PQSPS + S S N S + YSP S S S + S P P
Sbjct: 1610 PQSPSYSPTSPSYSPTSPSYSPT----SPNYSPTSPSYSPTS---PSYSPTSPSYSPTSP 1662
Query: 159 YHPPPLFPPSPQPPDSTPRQPEASFEP-HPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP 217
+ P SP P +P P S+ P PS +PT +P PTS P P P
Sbjct: 1663 SYSPTSPSYSPTSPSYSPTSP--SYSPTSPSYSPT---SPSYSPTS------PSYSPTSP 1711
Query: 218 QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT 277
P + P P + P + S +S S P PT
Sbjct: 1712 SYSPTSPSYSPTSPSYSPT-------------SPSYSPTSPSYSPTSPNYSPTSPNYTPT 1758
Query: 278 TPVGGGNLPS-APPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHLP-SPHA 334
+P PS +P N+ +PN P + S SP P P + P SP
Sbjct: 1759 SPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTY 1818
Query: 335 MGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394
P P PT SP P + S +P+ P P S S ++ S +S S
Sbjct: 1819 TPSSPSYSPSSPSYSPT---SPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYS 1875
Query: 395 SASPFPASQALPSYPHSFP--PPTSLSVSNQPPKYT------QPSLPSQAVWSQGPPPPP 446
SP S P Y + P PTS + PKY+ P+ P + S P
Sbjct: 1876 PTSP-TYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTS 1934
Query: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHPP 475
P G + ++ P P+ S A P
Sbjct: 1935 PKGSTYSPTSPGYSPTSPTYSLTSPAISP 1963
Score = 51.6 bits (122), Expect = 4e-06
Identities = 60/220 (27%), Positives = 81/220 (36%), Gaps = 42/220 (19%)
Query: 561 AGPNG-------PPVSSSSNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPVPTVTTSSA 612
AGP G P+ S + + +QG+ P SPS G P P+ + ++
Sbjct: 1496 AGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDAS 1555
Query: 613 TLSTVIATVASSPAGYKTASPPGPP-PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671
S SPA T PG P P PSPG A P Y P T P
Sbjct: 1556 GFSP-----GYSPAWSPTPGSPGSPGPSSPYIPSPGG---AMSPSYSP---------TSP 1598
Query: 672 GYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPA 731
Y P PG + P SP+ P PS P+ P+ + P S T P
Sbjct: 1599 AYE----PRSPGGYTPQSPSYSP-----TSPSYSPT---SPSYSPTSPNYSPTSPSYSPT 1646
Query: 732 EEYETPE----SPVPPARSPSPPPKVVDVPSHASQSARFN 767
+P SP P+ SP+ P PS++ S ++
Sbjct: 1647 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1686
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 119 bits (297), Expect = 2e-26
Identities = 183/744 (24%), Positives = 246/744 (33%), Gaps = 135/744 (18%)
Query: 93 EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPS-----IYSPGSVENDS-- 145
++ L R +S D SL S+ SS Q N S G V + S
Sbjct: 514 QEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIV 573
Query: 146 ---------------DSSSGLSQGPARPYHPPPLFPP-SPQPPDSTPRQPEASFEPHPSV 189
+SS + RPY L PP SPQP TP P P
Sbjct: 574 SSVFSEAWKRGTQLEESSKARMESMNRPY--TSLVPPLSPQPKIVTPYTASQPSPPLPPP 631
Query: 190 TPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG 249
P P PP PP PPP P L S PM K S++
Sbjct: 632 PP-----PPPPP-------PPPPPPPPPPLPSQSAPSAGSAAPMFVK----YSTITRLQN 675
Query: 250 GKQHP-----PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPP 304
QH PPT P+ S S KP G +P PPP PPP
Sbjct: 676 ASQHSGALFKPPTPPVMQSQS-------VKPQILVPPNGVVPPPPPP----------PPP 718
Query: 305 P----ALRPLNNASASP--PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
P A+ L A +P P A P P + + Q PP P P P
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP------PIPAP 772
Query: 359 LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSL 418
LPP AP P+ + +S+ + A + ++ + P P ++ P++P S+ PP
Sbjct: 773 LPP---QAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP--- 826
Query: 419 SVSNQPPKYTQPSLPSQAVWSQGPPPPP--PYGRLLAN--SNAHPGPFPPSTGAQSTAHP 474
S P P+LP Q + PPP P P ++ S P P PP+ +Q
Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPV 886
Query: 475 PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP 534
P + Q + + + +S P P FP P S P P
Sbjct: 887 PANV-----------APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP---PP 932
Query: 535 SLGSLRPYPPGPAHLPPPHSQVS-------YSQAGPNGPPVSSSSNSSSSTSQGSYPCSH 587
S P PP P P P S S G PP + NSS +S G+ H
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA---EH 989
Query: 588 PSPSQGPQGAPYP--FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG---KR 642
P P + + PP + + S TL A + PG G +
Sbjct: 990 PEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049
Query: 643 AP------SPGAYKTATPPGYK--PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGP 694
AP + +PP P PP PP P G P V P
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPI---EIPAVFSGNTSPKVAVVNP 1106
Query: 695 GPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVV 754
P + S + PP L+ +I ++P P+ P P S S P +
Sbjct: 1107 QPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFL 1166
Query: 755 ----------DVPSHASQSARFNK 768
+ H S S+R ++
Sbjct: 1167 ADLNRTLQRKSITRHGSLSSRMSR 1190
Score = 30.8 bits (68), Expect = 8.0
Identities = 33/116 (28%), Positives = 38/116 (32%), Gaps = 33/116 (28%)
Query: 673 YRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAE 732
Y PP P K +P P PP LPPPP P PP
Sbjct: 602 YTSLVPPLSPQP-KIVTPYTASQPSPP--------LPPPPPPP---PP------------ 637
Query: 733 EYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKH--LDRGFNSCARSDLYFVP 786
P PP P PP PS S + F K+ + R N+ S F P
Sbjct: 638 -------PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP 686
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 117 bits (293), Expect = 7e-26
Identities = 172/785 (21%), Positives = 273/785 (34%), Gaps = 77/785 (9%)
Query: 49 KSRQTAKKARVEEASTPKVN---KQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDL 105
K + T K V+EA + N K + + ++ + +PK T + PRP P +
Sbjct: 75 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 134
Query: 106 DSLDGRSL--NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP 163
D+ SL N + + + ++ N+ TS + ++ S S P
Sbjct: 135 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV- 193
Query: 164 LFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG 223
L P+P+ ++T + P + P TPT P EP ++ P P P
Sbjct: 194 LAKPTPKA-ETTTKGPALTTPKEP--TPT---TPKEPASTT-----PKEPTPT------- 235
Query: 224 TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT---KPPTTPV 280
+ P PK ++ P K+ P TT ++ AP T PTT
Sbjct: 236 ---TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292
Query: 281 GGGNLPSAPPPANFPHVTPNLPPPPA----LRPLNNASASPPGLGAQPLPGHLPSPHAMG 336
P P P P P PA P P +P P P
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP---- 348
Query: 337 QGMGGLPPGPEK-GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395
P P+K PT +P P + PAP S ++ A +++ S+ +++
Sbjct: 349 -----APTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400
Query: 396 ASPFP-ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA- 453
P P +++ P+ P P T+ + PK P+ P + + P P + A
Sbjct: 401 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 454 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513
+ P P P A +T T ++ ++ P P
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 520
Query: 514 AFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573
P P P A +P+ P P P P + P P ++
Sbjct: 521 E-PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEP------APTTPKEPAPTTPKE 569
Query: 574 SSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP 633
++ +T +G+ P + P+ P P PT TT T +T ++P G +P
Sbjct: 570 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-TTKEPTSTTCDKPAPTTPKGTAPTTP 628
Query: 634 PGPPPYGKRAPSPGAYKTATPPGYKPGSP-----PSFRTGTPPGYRG----TSPPAGPGT 684
P P + P+P K P K +P P+ + P +G TS P T
Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688
Query: 685 FKPGSPTV--GPGPLPPAGPS-GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE-SP 740
K +PT P P P P+ P PPP + S P + + + TPE S
Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 748
Query: 741 VPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVP---LEGSKLAKKRA 797
P ++ PK VP+ + +A + + DL P K+ K+ A
Sbjct: 749 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 808
Query: 798 DLVEK 802
EK
Sbjct: 809 TTTEK 813
Score = 82.0 bits (201), Expect = 3e-15
Identities = 162/804 (20%), Positives = 254/804 (31%), Gaps = 99/804 (12%)
Query: 35 PGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES--ESEETNAPKKTKT 92
P +T S+ ++ T K +TPK ++E + + +S T + T
Sbjct: 247 PAPTTTKSAPTTPKEPAPTTTKEPAP--TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304
Query: 93 EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS 152
+ P P +P + + +P ++ T+P +P + + +
Sbjct: 305 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA------- 357
Query: 153 QGPARPYHPPPLFPPSPQP---------------PDSTPRQPEASFEPHPSVTPTGYHAP 197
P P P P P P P P +T P + EP P+ T + P
Sbjct: 358 --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 198 MEP-PTSRMFQAP--PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254
EP PT+ AP P P P P T P + + P K+ P
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-P 474
Query: 255 PPTTPISVSSSGASGAPPTKP----PTTPVGGGNLPSAPPPANFPHVTPNLPPP--PALR 308
PTTP + + PT P PTTP P+ P TP P P P
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEP 530
Query: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGP-EKGPT----LAPSPHSLP-PA 362
A+ P +P P P A P P E PT AP+ P P
Sbjct: 531 APTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 589
Query: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN 422
+ PAP P ++ +S + ++ +P + P+ P P T +
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649
Query: 423 QPPKYTQPSLPSQ-------AVWSQGP-------PPPPPYGRLLANSNAHPGPFPPSTGA 468
K P+ P + ++GP P P + P P P A
Sbjct: 650 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 709
Query: 469 QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
+T P T ++ + + ++ P P P E G
Sbjct: 710 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 769
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
P A P + + L + + A P ++++ ++ S+ + +
Sbjct: 770 PAATKPEMTTTAKDKTTERDL---RTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826
Query: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGA 648
+ + P+ + T TT + ++T T+ ++ K P +
Sbjct: 827 TSTTTQDTTPFKITTLKT-TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS----- 880
Query: 649 YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708
K TP KP P T T P P KP + P P S +P L
Sbjct: 881 -KATTPKPQKPTKAPKKPTST------KKPKTMPRVRKPKTT-----PTPRKMTSTMPEL 928
Query: 709 PP----------PPAAPASGPPLSATQI--KQEPA--EEYETPESPV-PPARSPSPPPKV 753
P P P ++ K E A E ETP + P P P +
Sbjct: 929 NPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDM 988
Query: 754 VDVPSHASQSARFNKHLDRGFNSC 777
+P +Q N L N C
Sbjct: 989 DYLPRVPNQGIIINPMLSDETNIC 1012
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 117 bits (293), Expect = 7e-26
Identities = 172/785 (21%), Positives = 273/785 (34%), Gaps = 77/785 (9%)
Query: 49 KSRQTAKKARVEEASTPKVN---KQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDL 105
K + T K V+EA + N K + + ++ + +PK T + PRP P +
Sbjct: 116 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 175
Query: 106 DSLDGRSL--NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP 163
D+ SL N + + + ++ N+ TS + ++ S S P
Sbjct: 176 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV- 234
Query: 164 LFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG 223
L P+P+ ++T + P + P TPT P EP ++ P P P
Sbjct: 235 LAKPTPKA-ETTTKGPALTTPKEP--TPT---TPKEPASTT-----PKEPTPT------- 276
Query: 224 TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT---KPPTTPV 280
+ P PK ++ P K+ P TT ++ AP T PTT
Sbjct: 277 ---TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333
Query: 281 GGGNLPSAPPPANFPHVTPNLPPPPA----LRPLNNASASPPGLGAQPLPGHLPSPHAMG 336
P P P P P PA P P +P P P
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP---- 389
Query: 337 QGMGGLPPGPEK-GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395
P P+K PT +P P + PAP S ++ A +++ S+ +++
Sbjct: 390 -----APTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441
Query: 396 ASPFP-ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA- 453
P P +++ P+ P P T+ + PK P+ P + + P P + A
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 454 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513
+ P P P A +T T ++ ++ P P
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 561
Query: 514 AFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573
P P P A +P+ P P P P + P P ++
Sbjct: 562 E-PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEP------APTTPKEPAPTTPKE 610
Query: 574 SSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP 633
++ +T +G+ P + P+ P P PT TT T +T ++P G +P
Sbjct: 611 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-TTKEPTSTTCDKPAPTTPKGTAPTTP 669
Query: 634 PGPPPYGKRAPSPGAYKTATPPGYKPGSP-----PSFRTGTPPGYRG----TSPPAGPGT 684
P P + P+P K P K +P P+ + P +G TS P T
Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729
Query: 685 FKPGSPTV--GPGPLPPAGPS-GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE-SP 740
K +PT P P P P+ P PPP + S P + + + TPE S
Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 789
Query: 741 VPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVP---LEGSKLAKKRA 797
P ++ PK VP+ + +A + + DL P K+ K+ A
Sbjct: 790 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 849
Query: 798 DLVEK 802
EK
Sbjct: 850 TTTEK 854
Score = 82.0 bits (201), Expect = 3e-15
Identities = 162/804 (20%), Positives = 254/804 (31%), Gaps = 99/804 (12%)
Query: 35 PGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES--ESEETNAPKKTKT 92
P +T S+ ++ T K +TPK ++E + + +S T + T
Sbjct: 288 PAPTTTKSAPTTPKEPAPTTTKEPAP--TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345
Query: 93 EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS 152
+ P P +P + + +P ++ T+P +P + + +
Sbjct: 346 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA------- 398
Query: 153 QGPARPYHPPPLFPPSPQP---------------PDSTPRQPEASFEPHPSVTPTGYHAP 197
P P P P P P P P +T P + EP P+ T + P
Sbjct: 399 --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
Query: 198 MEP-PTSRMFQAP--PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254
EP PT+ AP P P P P T P + + P K+ P
Sbjct: 457 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-P 515
Query: 255 PPTTPISVSSSGASGAPPTKP----PTTPVGGGNLPSAPPPANFPHVTPNLPPP--PALR 308
PTTP + + PT P PTTP P+ P TP P P P
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEP 571
Query: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGP-EKGPT----LAPSPHSLP-PA 362
A+ P +P P P A P P E PT AP+ P P
Sbjct: 572 APTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 630
Query: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN 422
+ PAP P ++ +S + ++ +P + P+ P P T +
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690
Query: 423 QPPKYTQPSLPSQ-------AVWSQGP-------PPPPPYGRLLANSNAHPGPFPPSTGA 468
K P+ P + ++GP P P + P P P A
Sbjct: 691 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 750
Query: 469 QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
+T P T ++ + + ++ P P P E G
Sbjct: 751 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 810
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
P A P + + L + + A P ++++ ++ S+ + +
Sbjct: 811 PAATKPEMTTTAKDKTTERDL---RTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867
Query: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGA 648
+ + P+ + T TT + ++T T+ ++ K P +
Sbjct: 868 TSTTTQDTTPFKITTLKT-TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS----- 921
Query: 649 YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708
K TP KP P T T P P KP + P P S +P L
Sbjct: 922 -KATTPKPQKPTKAPKKPTST------KKPKTMPRVRKPKTT-----PTPRKMTSTMPEL 969
Query: 709 PP----------PPAAPASGPPLSATQI--KQEPA--EEYETPESPV-PPARSPSPPPKV 753
P P P ++ K E A E ETP + P P P +
Sbjct: 970 NPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDM 1029
Query: 754 VDVPSHASQSARFNKHLDRGFNSC 777
+P +Q N L N C
Sbjct: 1030 DYLPRVPNQGIIINPMLSDETNIC 1053
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 117 bits (293), Expect = 7e-26
Identities = 172/785 (21%), Positives = 273/785 (34%), Gaps = 77/785 (9%)
Query: 49 KSRQTAKKARVEEASTPKVN---KQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDL 105
K + T K V+EA + N K + + ++ + +PK T + PRP P +
Sbjct: 168 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 227
Query: 106 DSLDGRSL--NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP 163
D+ SL N + + + ++ N+ TS + ++ S S P
Sbjct: 228 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV- 286
Query: 164 LFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG 223
L P+P+ ++T + P + P TPT P EP ++ P P P
Sbjct: 287 LAKPTPKA-ETTTKGPALTTPKEP--TPT---TPKEPASTT-----PKEPTPT------- 328
Query: 224 TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT---KPPTTPV 280
+ P PK ++ P K+ P TT ++ AP T PTT
Sbjct: 329 ---TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385
Query: 281 GGGNLPSAPPPANFPHVTPNLPPPPA----LRPLNNASASPPGLGAQPLPGHLPSPHAMG 336
P P P P P PA P P +P P P
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP---- 441
Query: 337 QGMGGLPPGPEK-GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395
P P+K PT +P P + PAP S ++ A +++ S+ +++
Sbjct: 442 -----APTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 396 ASPFP-ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA- 453
P P +++ P+ P P T+ + PK P+ P + + P P + A
Sbjct: 494 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 454 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513
+ P P P A +T T ++ ++ P P
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 613
Query: 514 AFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573
P P P A +P+ P P P P + P P ++
Sbjct: 614 E-PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEP------APTTPKEPAPTTPKE 662
Query: 574 SSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP 633
++ +T +G+ P + P+ P P PT TT T +T ++P G +P
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-TTKEPTSTTCDKPAPTTPKGTAPTTP 721
Query: 634 PGPPPYGKRAPSPGAYKTATPPGYKPGSP-----PSFRTGTPPGYRG----TSPPAGPGT 684
P P + P+P K P K +P P+ + P +G TS P T
Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781
Query: 685 FKPGSPTV--GPGPLPPAGPS-GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE-SP 740
K +PT P P P P+ P PPP + S P + + + TPE S
Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 841
Query: 741 VPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVP---LEGSKLAKKRA 797
P ++ PK VP+ + +A + + DL P K+ K+ A
Sbjct: 842 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 901
Query: 798 DLVEK 802
EK
Sbjct: 902 TTTEK 906
Score = 82.0 bits (201), Expect = 3e-15
Identities = 162/804 (20%), Positives = 254/804 (31%), Gaps = 99/804 (12%)
Query: 35 PGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES--ESEETNAPKKTKT 92
P +T S+ ++ T K +TPK ++E + + +S T + T
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAP--TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 93 EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS 152
+ P P +P + + +P ++ T+P +P + + +
Sbjct: 398 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA------- 450
Query: 153 QGPARPYHPPPLFPPSPQP---------------PDSTPRQPEASFEPHPSVTPTGYHAP 197
P P P P P P P P +T P + EP P+ T + P
Sbjct: 451 --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508
Query: 198 MEP-PTSRMFQAP--PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254
EP PT+ AP P P P P T P + + P K+ P
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-P 567
Query: 255 PPTTPISVSSSGASGAPPTKP----PTTPVGGGNLPSAPPPANFPHVTPNLPPP--PALR 308
PTTP + + PT P PTTP P+ P TP P P P
Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEP 623
Query: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGP-EKGPT----LAPSPHSLP-PA 362
A+ P +P P P A P P E PT AP+ P P
Sbjct: 624 APTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 682
Query: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN 422
+ PAP P ++ +S + ++ +P + P+ P P T +
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742
Query: 423 QPPKYTQPSLPSQ-------AVWSQGP-------PPPPPYGRLLANSNAHPGPFPPSTGA 468
K P+ P + ++GP P P + P P P A
Sbjct: 743 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 802
Query: 469 QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
+T P T ++ + + ++ P P P E G
Sbjct: 803 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 862
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
P A P + + L + + A P ++++ ++ S+ + +
Sbjct: 863 PAATKPEMTTTAKDKTTERDL---RTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 919
Query: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGA 648
+ + P+ + T TT + ++T T+ ++ K P +
Sbjct: 920 TSTTTQDTTPFKITTLKT-TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS----- 973
Query: 649 YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708
K TP KP P T T P P KP + P P S +P L
Sbjct: 974 -KATTPKPQKPTKAPKKPTST------KKPKTMPRVRKPKTT-----PTPRKMTSTMPEL 1021
Query: 709 PP----------PPAAPASGPPLSATQI--KQEPA--EEYETPESPV-PPARSPSPPPKV 753
P P P ++ K E A E ETP + P P P +
Sbjct: 1022 NPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDM 1081
Query: 754 VDVPSHASQSARFNKHLDRGFNSC 777
+P +Q N L N C
Sbjct: 1082 DYLPRVPNQGIIINPMLSDETNIC 1105
Score = 49.7 bits (117), Expect = 2e-05
Identities = 84/427 (19%), Positives = 146/427 (34%), Gaps = 79/427 (18%)
Query: 387 SSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446
+S SS + P ASQ + S P P + K T+ + S+ + +
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPN-------KKKTKKVIESEEITEEHS---- 118
Query: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN 506
+ N S+ + ST S+ + ++ Q++ + + ++ + +
Sbjct: 119 ------VSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 172
Query: 507 SGPPPPGAFPHPLEGG---------SSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVS 557
PP L+ G S+ + + SP + + +P P P+ PP+S S
Sbjct: 173 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL--PPNSDTS 230
Query: 558 YS---------------------QAGPNGPPVSSSSNSSSSTSQGSYP--------CSHP 588
Q +G ++S+ + S + S + P
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290
Query: 589 SP-----SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP-----PP 638
+P ++GP P P PT A+ + T + + T P P P
Sbjct: 291 TPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP 698
+ P+P K P K +P + + P T+ + P T K +PT P P
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-----TTTKSAPTTPKEPAPTTPKKPAP 404
Query: 699 PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPA-RSPSPPPKVVDVP 757
P+ P P P T +EPA TP+ P P A + P+P P
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTT---KEPAP--TTPKEPAPTAPKKPAPTTPKEPAP 459
Query: 758 SHASQSA 764
+ + A
Sbjct: 460 TTPKEPA 466
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 117 bits (293), Expect = 7e-26
Identities = 172/785 (21%), Positives = 273/785 (34%), Gaps = 77/785 (9%)
Query: 49 KSRQTAKKARVEEASTPKVN---KQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDL 105
K + T K V+EA + N K + + ++ + +PK T + PRP P +
Sbjct: 209 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNS 268
Query: 106 DSLDGRSL--NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP 163
D+ SL N + + + ++ N+ TS + ++ S S P
Sbjct: 269 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV- 327
Query: 164 LFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG 223
L P+P+ ++T + P + P TPT P EP ++ P P P
Sbjct: 328 LAKPTPKA-ETTTKGPALTTPKEP--TPT---TPKEPASTT-----PKEPTPT------- 369
Query: 224 TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT---KPPTTPV 280
+ P PK ++ P K+ P TT ++ AP T PTT
Sbjct: 370 ---TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426
Query: 281 GGGNLPSAPPPANFPHVTPNLPPPPA----LRPLNNASASPPGLGAQPLPGHLPSPHAMG 336
P P P P P PA P P +P P P
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP---- 482
Query: 337 QGMGGLPPGPEK-GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395
P P+K PT +P P + PAP S ++ A +++ S+ +++
Sbjct: 483 -----APTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 396 ASPFP-ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA- 453
P P +++ P+ P P T+ + PK P+ P + + P P + A
Sbjct: 535 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 454 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513
+ P P P A +T T ++ ++ P P
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 654
Query: 514 AFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573
P P P A +P+ P P P P + P P ++
Sbjct: 655 E-PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEP------APTTPKEPAPTTPKE 703
Query: 574 SSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASP 633
++ +T +G+ P + P+ P P PT TT T +T ++P G +P
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-TTKEPTSTTCDKPAPTTPKGTAPTTP 762
Query: 634 PGPPPYGKRAPSPGAYKTATPPGYKPGSP-----PSFRTGTPPGYRG----TSPPAGPGT 684
P P + P+P K P K +P P+ + P +G TS P T
Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822
Query: 685 FKPGSPTV--GPGPLPPAGPS-GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE-SP 740
K +PT P P P P+ P PPP + S P + + + TPE S
Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA 882
Query: 741 VPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVP---LEGSKLAKKRA 797
P ++ PK VP+ + +A + + DL P K+ K+ A
Sbjct: 883 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 942
Query: 798 DLVEK 802
EK
Sbjct: 943 TTTEK 947
Score = 82.0 bits (201), Expect = 3e-15
Identities = 162/804 (20%), Positives = 254/804 (31%), Gaps = 99/804 (12%)
Query: 35 PGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES--ESEETNAPKKTKT 92
P +T S+ ++ T K +TPK ++E + + +S T + T
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAP--TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 93 EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS 152
+ P P +P + + +P ++ T+P +P + + +
Sbjct: 439 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA------- 491
Query: 153 QGPARPYHPPPLFPPSPQP---------------PDSTPRQPEASFEPHPSVTPTGYHAP 197
P P P P P P P P +T P + EP P+ T + P
Sbjct: 492 --PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549
Query: 198 MEP-PTSRMFQAP--PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254
EP PT+ AP P P P P T P + + P K+ P
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-P 608
Query: 255 PPTTPISVSSSGASGAPPTKP----PTTPVGGGNLPSAPPPANFPHVTPNLPPP--PALR 308
PTTP + + PT P PTTP P+ P TP P P P
Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTP----EKPAPTTPEELAPTTPEEPTPTTPEEP 664
Query: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGP-EKGPT----LAPSPHSLP-PA 362
A+ P +P P P A P P E PT AP+ P P
Sbjct: 665 APTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT 723
Query: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN 422
+ PAP P ++ +S + ++ +P + P+ P P T +
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783
Query: 423 QPPKYTQPSLPSQ-------AVWSQGP-------PPPPPYGRLLANSNAHPGPFPPSTGA 468
K P+ P + ++GP P P + P P P A
Sbjct: 784 TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 843
Query: 469 QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
+T P T ++ + + ++ P P P E G
Sbjct: 844 PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 903
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
P A P + + L + + A P ++++ ++ S+ + +
Sbjct: 904 PAATKPEMTTTAKDKTTERDL---RTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 960
Query: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGA 648
+ + P+ + T TT + ++T T+ ++ K P +
Sbjct: 961 TSTTTQDTTPFKITTLKT-TTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNS----- 1014
Query: 649 YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708
K TP KP P T T P P KP + P P S +P L
Sbjct: 1015 -KATTPKPQKPTKAPKKPTST------KKPKTMPRVRKPKTT-----PTPRKMTSTMPEL 1062
Query: 709 PP----------PPAAPASGPPLSATQI--KQEPA--EEYETPESPV-PPARSPSPPPKV 753
P P P ++ K E A E ETP + P P P +
Sbjct: 1063 NPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDM 1122
Query: 754 VDVPSHASQSARFNKHLDRGFNSC 777
+P +Q N L N C
Sbjct: 1123 DYLPRVPNQGIIINPMLSDETNIC 1146
Score = 49.7 bits (117), Expect = 2e-05
Identities = 84/427 (19%), Positives = 146/427 (34%), Gaps = 79/427 (18%)
Query: 387 SSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446
+S SS + P ASQ + S P P + K T+ + S+ + +
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPN-------KKKTKKVIESEEITEEHS---- 159
Query: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN 506
+ N S+ + ST S+ + ++ Q++ + + ++ + +
Sbjct: 160 ------VSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 213
Query: 507 SGPPPPGAFPHPLEGG---------SSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVS 557
PP L+ G S+ + + SP + + +P P P+ PP+S S
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSL--PPNSDTS 271
Query: 558 YS---------------------QAGPNGPPVSSSSNSSSSTSQGSYP--------CSHP 588
Q +G ++S+ + S + S + P
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331
Query: 589 SP-----SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGP-----PP 638
+P ++GP P P PT A+ + T + + T P P P
Sbjct: 332 TPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP 698
+ P+P K P K +P + + P T+ + P T K +PT P P
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP-----TTTKSAPTTPKEPAPTTPKKPAP 445
Query: 699 PAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPA-RSPSPPPKVVDVP 757
P+ P P P T +EPA TP+ P P A + P+P P
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTT---KEPAP--TTPKEPAPTAPKKPAPTTPKEPAP 500
Query: 758 SHASQSA 764
+ + A
Sbjct: 501 TTPKEPA 507
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 116 bits (290), Expect = 1e-25
Identities = 222/851 (26%), Positives = 287/851 (33%), Gaps = 175/851 (20%)
Query: 131 TSPSIYSPGSVENDSDSSSGLSQGPARP--YHPPPLFPPSPQPPDSTPR------QPEAS 182
T+P PGS+ + S S A P PP L P P S+PR P +
Sbjct: 154 TTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPA 213
Query: 183 FEPHPSV-----------------------TPTGYHA----PMEPPTSRMFQA--PPGAP 213
P P++ +P HA P +PP A PP P
Sbjct: 214 PPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLP 273
Query: 214 P-------PHPQLYPGGTGGVLSGP-PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSS 265
P P P P + + P +GP GG A +V GP PP +S++
Sbjct: 274 PSNNLPAHPGPASQPPVSSATMHLPLVLGPLGG--APTVEGPGA----PPFLASSLLSAA 327
Query: 266 GASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN----LPPPPALRPLNNASASPPGLG 321
+ PP PP+T G AP ++ + P+ PP R L P
Sbjct: 328 AKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRS 387
Query: 322 AQPLPGHLPSPHAMGQ----------GMGGLP-PGPEKGP----TLAPSPHSLPPASSSA 366
P +P P ++ + + GLP PGP L H PP + S+
Sbjct: 388 RPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSS 447
Query: 367 PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF--PPPTSLSVSNQP 424
+PP P S +S S SS A PA+ P P P L + P
Sbjct: 448 GSPPQ--PRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGP 505
Query: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGA----QSTAHPPVSTHH 480
LP A P P P G L+ + FP GA S PP S
Sbjct: 506 ----ACPLPPLAGGEAFPFPSPEQGLALSGAG-----FPGMLGALPLPLSLGQPPPSPLL 556
Query: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL--GS 538
+H G G PPP P G A PSL S
Sbjct: 557 NHSLFGVLT---------------GGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVAS 601
Query: 539 LRPYPPG----PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP 594
L P PP P PP + S+ GP ++ + S P P G
Sbjct: 602 LLPPPPSDLLPPPSAPPSNLLASFLPLLALGP---TAGDGEGSAEGAGGPSGEPFSGLGD 658
Query: 595 QGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSP--GAYKTA 652
+P FPP+ T A S ++A P+G +PP P P P + TA
Sbjct: 659 L-SPLLFPPLSAPPTLIALNSALLAATLDPPSG----TPPQPCVLSAPQPGPPTSSVTTA 713
Query: 653 T--PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP-GSPTVGPGPLP----PAGP--- 702
T P G PS +G PP + SP G S T PG LP P GP
Sbjct: 714 TTDPGASSLGKAPS-NSGRPP--QLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLS 770
Query: 703 --SGLPSLP----PPPAAPASGPPLSATQIKQEPAEEYET----PESP------------ 740
GL LP PPP + AS P Q Q P E+ E PESP
Sbjct: 771 GQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPP 830
Query: 741 ----VPPARSPSPP-PKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKK 795
PP SP PP P+++ + R L RG N AR P G K
Sbjct: 831 LSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGL-RGINGEAR------PARGRKPGS- 882
Query: 796 RADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLG 855
RRE + A + R + ER + + + +LA+ G P + P G
Sbjct: 883 --------RREPGRLALKWGTR-GGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPG 933
Query: 856 PVPHRPPFEPG 866
P PG
Sbjct: 934 PHSEDLKVPPG 944
Score = 107 bits (267), Expect = 7e-23
Identities = 146/511 (28%), Positives = 197/511 (38%), Gaps = 81/511 (15%)
Query: 261 SVSSSGASGAPPTK-PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG 319
+VS S PP + PPTTP+ GG P P + P L P L P A P G
Sbjct: 137 TVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSG 196
Query: 320 LGAQP--LP-GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH-------SLPPASSSAPAP 369
+ P LP G+ PSP PP P APS + SL P+ +P
Sbjct: 197 GSSSPRFLPRGNAPSP---------APPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPA 247
Query: 370 PMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429
P +SSS + S + + P P S LP++P P S + P
Sbjct: 248 P-----HASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLG 302
Query: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNA-HPGPFPPST--GAQSTAHPPVSTHHHHHQQQ 486
P + V G PP L A + A HP PPST G + A P ++H +
Sbjct: 303 PLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPS 362
Query: 487 QQQQQQQ----QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPY 542
Q++ ++ + + + Q S P P P P S + PS+ SL
Sbjct: 363 QRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPF----SLPEPSQPILPSVLSLLGL 418
Query: 543 P-PGP-------------AHLPPPHSQVSYSQAGPNGP-----PVSSSSNSSSSTSQGSY 583
P PGP AHLPPP + S S P P P ++S + SS +
Sbjct: 419 PTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAP 478
Query: 584 PCSH----------PSPSQGPQGAPYPFPPVPTVTTSSA-TLSTVIATVASSPAGY--KT 630
P + SPS+G P P+P + A + +A S AG+
Sbjct: 479 PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML 538
Query: 631 ASPPGPPPYGKRAPSP----GAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFK 686
+ P P G+ PSP + T G G PP PPG G PP PG +
Sbjct: 539 GALPLPLSLGQPPPSPLLNHSLFGVLTGGG---GQPPPEPLLPPPG--GPGPPLAPG--E 591
Query: 687 PGSPTVGPGPLPPAGPSGLPSLPPPPAAPAS 717
P P++ L P PS L LPPP A P++
Sbjct: 592 PEGPSLLVASLLPPPPSDL--LPPPSAPPSN 620
Score = 72.0 bits (175), Expect = 3e-12
Identities = 165/643 (25%), Positives = 212/643 (32%), Gaps = 91/643 (14%)
Query: 156 ARPYHPPPLFPPSPQPPDSTPRQPEA-SFEPHPSVTPT---------GYHAPMEPPTSRM 205
+RP P P+ P P S P P S P+ P+ G A + PP +
Sbjct: 387 SRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLS 446
Query: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSS 265
+PP P PG T G LS P P A+ + P+ Q P S
Sbjct: 447 SGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP--------SEG 498
Query: 266 GASGAPPTKPPTTPVGGGNLPSAPPP--------ANFPHVTPNLP-------PPPALRPL 310
GA P P P+ GG P P A FP + LP PPP+ PL
Sbjct: 499 LGMGAGPA-CPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS--PL 555
Query: 311 NNAS--ASPPGLGAQPLPGH-LPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAP 367
N S G G QP P LP P G L PG +GP+L + PP S P
Sbjct: 556 LNHSLFGVLTGGGGQPPPEPLLPPPGGPGP---PLAPGEPEGPSLLVASLLPPPPSDLLP 612
Query: 368 ---APPMRFPYS----SSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420
APP S + +A S+ + S P S P FPP ++
Sbjct: 613 PPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSA--- 669
Query: 421 SNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHH 480
PP + A P PP +L S PGP P S+ +T P S+
Sbjct: 670 ---PPTLIALNSALLAATLDPPSGTPPQPCVL--SAPQPGP-PTSSVTTATTDPGASSLG 723
Query: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
+ Q +S PGA P L+ +S LG L+
Sbjct: 724 KAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGP------LLSGQLG-LQ 776
Query: 541 PYPPGPAHLPPPHSQVSYS--------QAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPS 591
P G A PPP S+ S Q P P S +++ P P S
Sbjct: 777 LLPGGGA--PPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSAL 834
Query: 592 QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP-GPPPYGKRAPSPGAYK 650
P G+ P PPVP + T + A P G P +R P A K
Sbjct: 835 APPHGS--PDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALK 892
Query: 651 TATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPP 710
T G+ S R + G G +P P PP GP P
Sbjct: 893 WGTRGGFNGQMERSPRRTHHWQHNGELAEGGA---EPKDP-------PPPGPHSEDLKVP 942
Query: 711 PPAAPAS--GPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
P S G + + + P P AR+ P P
Sbjct: 943 PGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLP 985
Score = 41.2 bits (95), Expect = 0.006
Identities = 60/227 (26%), Positives = 78/227 (34%), Gaps = 44/227 (19%)
Query: 563 PNGPPVSSSSNSSSST-SQGSYPCSHPSPSQGPQGAPYPFPPVPTVT------------- 608
P+G +SS + S S G+ C P P+ + F P+ VT
Sbjct: 39 PSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPK--VFNFDPLAPVTPGGAGVGPASEED 96
Query: 609 -----------TSSATLSTVIATVASSPAGYKTASP-------PGPPPYGKRAPSPGAYK 650
+ ATL + T S + + ASP PGPP P
Sbjct: 97 MTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTP 156
Query: 651 TATPPGYKPGSPPSFRTGTPP--GYRGTSPP--AGPGTFKPGSPTVGPGPLPPAGPSGLP 706
PG P PPS P G G PP A P P + P LP G + P
Sbjct: 157 LNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADP---VPSGGSSSPRFLP-RGNAPSP 212
Query: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS--PSPPP 751
+ PPPPA + P + + + P P A S PS PP
Sbjct: 213 APPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPP 259
Score = 33.5 bits (75), Expect = 1.2
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 11/77 (14%)
Query: 691 TVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750
TV PGP PS P PP P +G P S ++ + T P P
Sbjct: 137 TVSPGP-----PSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGP-----GGLFP 186
Query: 751 PKVVD-VPSHASQSARF 766
P++ D VPS S S RF
Sbjct: 187 PRLADPVPSGGSSSPRF 203
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 115 bits (289), Expect = 2e-25
Identities = 171/654 (26%), Positives = 218/654 (33%), Gaps = 135/654 (20%)
Query: 158 PYHPPPLFPPSPQPPDSTPRQ--PEAS-FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
P PPP P PP+ +P PEAS P P P P SR + P +PP
Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS-PLPEALHLSRPLEESPLSPP 497
Query: 215 PHPQLYPGGTGGVLSGPP-MGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273
P LS PP P S + P P TP+S + +PP
Sbjct: 498 PEE--------SPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF 549
Query: 274 KPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN----NASASPPGLGAQPLPGHL 329
+ LP++PPP L PPP P++ + SPP ++ P
Sbjct: 550 EESPLSPPPEELPTSPPPE-----ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604
Query: 330 PSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS 389
SP L P PE+ SP S PP +S PP P S S S
Sbjct: 605 ESP---------LSPPPEE------SPLSPPPEASRLSPPPEDSPMSPPPEES---PMSP 646
Query: 390 SSSSSSASPFPASQALPSYPHSFP--PPTSLSVSNQPPKYTQPSLPSQAVWSQGPP---- 443
S SP P L P P PP S ++ PP+ ++ S P + + PP
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Query: 444 -PPPPYGRL----LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQ 498
PPP L L S P P P +S P +S + + ++
Sbjct: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLSP--RPEEPHLSPRPEEPHLSP 763
Query: 499 QQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSY 558
Q ++ H + P P P E H P A P L P HL P +
Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEE----PHLSPQAEGPHLSP----QPEELHLSPQTEEPHL 815
Query: 559 SQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVI 618
S P P +S S + Q PC P P + PP+
Sbjct: 816 SPV-PEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL-------------- 860
Query: 619 ATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP 678
SP K PG P +P PPG SP
Sbjct: 861 -----SPRPEKPPEEPGQCP----------------------APEELPLFPPPGEPSLSP 893
Query: 679 PAG-PGTFKPGSPTVGPGPLP-PAGPSGLPSLP---------PPPAAP----ASGPPLSA 723
G P +PG P + P P P PSG PSL PPP +P A+ P LS
Sbjct: 894 LLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP 953
Query: 724 TQIKQEP--------------AEEYETPESPVPPAR--SPSPPPKVVDVPSHAS 761
+ P A ETP SP P A P P P ++ PS S
Sbjct: 954 LGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007
Score = 110 bits (276), Expect = 6e-24
Identities = 168/649 (25%), Positives = 219/649 (33%), Gaps = 90/649 (13%)
Query: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP 215
+RP PL PP P+ +P P P + + P E P S + P PP
Sbjct: 486 SRPLEESPLSPP----PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541
Query: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP-TTPISVSSSGASGAPPTK 274
L P LS PP + P + PPP +P+S + +PP +
Sbjct: 542 ASPLSPPFEESPLSPPP------EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR---PLNNASASPPGLGAQPLPGHLPS 331
P +PPP +P PPP A R P ++ SPP + P S
Sbjct: 596 ASRLFPPFEESPLSPPPEE----SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
Query: 332 PHAMGQGMGGLPPGPEKGPTLAP---SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSS 388
+ + L P PE+ P P SP S PP +S PP P S S A+
Sbjct: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711
Query: 389 SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP------PKYTQPSLPSQAVWSQGP 442
S S LP P P +S +P P+ +P L QA +
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQA--EEPH 769
Query: 443 PPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQ---QQQ 499
P P L P P + G + P H Q ++ ++ Q
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP--EELHLSPQTEEPHLSPVPEEPCLSPQ 827
Query: 500 QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP-GPAHLPPPHSQVSY 558
++ H + P P P E H P P L PP P P P +
Sbjct: 828 PEESHLSPQSEEPCLSPRPEES----HLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF 883
Query: 559 SQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ---GPQGAPYPFPPVPTVTTSSATLS 615
P G P S + S+ P P P + P G P P + LS
Sbjct: 884 P---PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLS 940
Query: 616 TVIATVASSPAGYKTASPPG--PPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGY 673
+I T A+ PA SP G P+G + S A P P SP PP
Sbjct: 941 PII-TAAAPPA----LSPLGELEYPFGAKGDSDPESPLAAPILETPISP-------PPEA 988
Query: 674 RGTSPPAGPGTFKPGSP--TVGPG------PLPP----------AGPSGLPSLPPPPAAP 715
T P P P SP VGP PLPP + PS PPA P
Sbjct: 989 NCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALP 1048
Query: 716 ASGP-PLS----------ATQIKQEPAEEYETPESPV--PPARSPSPPP 751
S P PLS ++ + E+ PE P P A SP P P
Sbjct: 1049 LSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097
Score = 92.0 bits (227), Expect = 3e-18
Identities = 200/803 (24%), Positives = 259/803 (32%), Gaps = 169/803 (21%)
Query: 81 SEETNAPKKTKTEQELPRPQSPSDLD---SLDGRSLNDDGSSDPRDIDQDNRSTSPSIYS 137
S A + + +ELP P L L+ L+ P ++ SP S
Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518
Query: 138 PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ-------PEAS-FEPHPS- 188
P S +S S L + P PL PP + P S P + PEAS P P
Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578
Query: 189 --VTPTGYHAPMEPP--TSRMF----QAPPGAPPPHPQLYPGGTGGVLSGPP----MGPK 236
++P +PM PP SR+F ++P PP L P LS PP M P
Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
Query: 237 GGGAASSVGG--------PNGGKQHPPPT-TPISVSSSGASGAPPTKPPTTPVGGGNLPS 287
+ S P + PPP +P+S + +PP + + P+
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPT 698
Query: 288 APPPANFPHVTPN----------------LPPPPALRPLNNAS-ASP----PGLGAQPLP 326
+PPP + P P LP P L P + SP P L +P
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758
Query: 327 GHLPSPHAMGQGMGGLPPGP--------------EKGPTLAPSPHSL-------PPASSS 365
HL SP A + P P +GP L+P P L P S
Sbjct: 759 PHL-SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817
Query: 366 APAPPMRFPYSSSSSSSAAASS---SSSSSSSSASP-------FPASQALPSYPHSFPPP 415
P P P S S + S S SP P + P P P P
Sbjct: 818 VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAP 877
Query: 416 TSLSVSNQPPKYT-QPSLPSQAVWSQGPPPPPPYGRLLANSNAH----------PGPFPP 464
L + P + + P L A+ G PP P L S + P P PP
Sbjct: 878 EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPP 937
Query: 465 STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSS 524
TA P + + + G+S P P A P LE
Sbjct: 938 PLSPIITAAAPPAL-------------SPLGELEYPFGAKGDSDPESPLAAPI-LET--- 980
Query: 525 HHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP-------PVSSSSNSSSS 577
P + P P P P LPP S GP P P S S
Sbjct: 981 ----PISPPPEANCTDPEPVPPMILPPSPG----SPVGPASPILMEPLPPQCSPLLQHSL 1032
Query: 578 TSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT-----LSTVIATVASSPAGYKTAS 632
Q S P S SP P P P P+ V S + T + PA +A+
Sbjct: 1033 VPQNSPP-SQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSAT 1091
Query: 633 PPGPPPYGKR---APSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGP--GTFKP 687
P P P G APSP P+ + G P G P
Sbjct: 1092 SPLPSPMGDLSCPAPSPA---------------PAL-----DDFSGLGEDTAPLDGIDAP 1131
Query: 688 GSPTVGPGPLPPAGPSGLPSLP----PPPAAPASG----PPLSATQIKQEPAEEYETPES 739
GS PG P + S L P P AP + P T + P EE E P +
Sbjct: 1132 GSQPE-PGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRA 1190
Query: 740 PVPPARSPSPPPKVVDVPSHASQ 762
PV P +V+ S+ SQ
Sbjct: 1191 PVAPTPPTLIKSDIVNEISNLSQ 1213
Score = 92.0 bits (227), Expect = 3e-18
Identities = 154/603 (25%), Positives = 193/603 (32%), Gaps = 87/603 (14%)
Query: 154 GPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
G P P +F SP P + +P P G + P + PP P
Sbjct: 2114 GSPPPAAAPTIFIGSPTTPAGLSTSADGFLKP-----PAGSVPGPDSPGELFLKLPPQVP 2168
Query: 214 PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT 273
P P G P P P G PP S +G G T
Sbjct: 2169 AQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHT 2228
Query: 274 KPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333
PP TP + PS P P P P+L N A PG+G L SP
Sbjct: 2229 TPPGTP---RHQPSTPDPFLKPR-CPSLD--------NLAVPESPGVGGGKASEPLLSP- 2275
Query: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS 393
PP E L L +S S P + F S SS + +
Sbjct: 2276 ---------PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDV 2326
Query: 394 SSASPFP-ASQALPSYP----HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY 448
A P ASQ P P PP + +++ PP + P PP P
Sbjct: 2327 FKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP- 2385
Query: 449 GRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508
P P PP + A PP S + Q Q Q
Sbjct: 2386 ---------RPQPPPPES---CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR----- 2428
Query: 509 PPPPGAF-PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP 567
P AF P P+ PY+ PS R P P H PP P P
Sbjct: 2429 PLSAEAFCPSPVT-PRFQSPDPYSRPPSRPQSRD-PFAPLHKPP----------RPQPPE 2476
Query: 568 VSSSSNSSSSTS--QGSYPCSHPSPSQG------PQGAPYPFPPVPTVTTSSATLSTVIA 619
V+ + S + TS G +P + P+ G P G P F P T S +
Sbjct: 2477 VAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRF 2536
Query: 620 TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPG-YRGTSP 678
T + G + PP P P P P + PG G P S G + +
Sbjct: 2537 TFPQA-VGEPSLKPPVPQP---GLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGS 2592
Query: 679 PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLS--ATQIK--QEPAEEY 734
P GP + G + G PL P PS+ PPPA S P LS A+Q P E+
Sbjct: 2593 PLGPSSGSTGE-SYGLSPLRP------PSVLPPPAPDGSLPYLSHGASQRSGITSPVEKR 2645
Query: 735 ETP 737
E P
Sbjct: 2646 EDP 2648
Score = 89.4 bits (220), Expect = 2e-17
Identities = 165/688 (23%), Positives = 241/688 (35%), Gaps = 147/688 (21%)
Query: 288 APPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPE 347
+PPPA P + P PA S S G +P G +P P + G+ LPP
Sbjct: 2115 SPPPAAAPTIFIGSPTTPA-----GLSTSADGF-LKPPAGSVPGPDSPGELFLKLPP--- 2165
Query: 348 KGPTLAPS--PHSLPPASSSAP----APPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
+ P PS P L PA P APP PY S + + A +SS A
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQ--- 2222
Query: 402 SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP-------------PPPY 448
P H+ PP T + P + +P PS + P PPP+
Sbjct: 2223 ----PGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPF 2278
Query: 449 GRL----------LANSNAHPGP------FPPSTGAQ----STAHPPVSTHHHHHQQQQQ 488
G L S+ GP PS+G P V + Q
Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV 2338
Query: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH 548
+ Q + Q+ + P P + P GS + PYA P +P PP
Sbjct: 2339 EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGS--YTDPYAQPPLTPRPQPPPPESCC 2396
Query: 549 LPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS-----------------QGSYPCSHPSPS 591
PP S S + P S SS+ S T Q P S P PS
Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP-PS 2455
Query: 592 QGPQGAPY------PFPPVPTVTTSSATLSTVI-------ATVASSPAGYKTAS-PPGPP 637
+ P+ P P P V + +L+ A + + PAG A P G P
Sbjct: 2456 RPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP 2515
Query: 638 PYGKRAPSPGAYKTATPP---------GYKPGSPPSFRTGTPPGYRGTSPPAGPGTF--K 686
P R+P GA+ P G PP + G PP + G + GPG K
Sbjct: 2516 PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPH-GINSHFGPGPTLGK 2574
Query: 687 PGSP--TVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPA 744
P S TV G P+G P P++ ++G + ++ P S +PP
Sbjct: 2575 PQSTNYTVATGNFHPSGS------PLGPSSGSTGESYGLSPLR---------PPSVLPP- 2618
Query: 745 RSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVR 804
P+P + + ASQ + +++ R D G+ + A
Sbjct: 2619 --PAPDGSLPYLSHGASQRSGITSPVEK------RED------PGTGMGSSLATAELPGT 2664
Query: 805 REAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFE 864
++ + E E++R+R++ RE ++++R+ ++ A ++GP
Sbjct: 2665 QDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGP-------- 2716
Query: 865 PGSAVATVPPYLGPDTPALRTLSEYARP 892
PGS A P +PA LS P
Sbjct: 2717 PGSWGAE------PSSPAFEQLSRGQTP 2738
Score = 87.0 bits (214), Expect = 9e-17
Identities = 138/531 (25%), Positives = 172/531 (32%), Gaps = 95/531 (17%)
Query: 510 PPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP-GPAHLPPPHSQVSYSQAGPNGPPV 568
PPP P + H + P SP L P P P PP S S + P PP
Sbjct: 469 PPPEELPASPLPEALHLSRPLEESP----LSPPPEESPLSPPPESSPFSPLEESPLSPPE 524
Query: 569 SSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY 628
S + + T P S P P P P+ P+ T A+ S P
Sbjct: 525 ESPPSPALET-----PLS-PPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE 578
Query: 629 KTASPP------GPPPYGKRAPSPGAYKTATPPGYK-PGSPP--SFRTGTPPGYRGTSPP 679
SPP PPP R P +PP + P SPP + R PP SPP
Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP 638
Query: 680 AGPGTFKPGSPTVGPGPLPPAG-----PSGLPSLPPPPAAPASGPPLSATQIKQEPAEEY 734
P PLP P P PPP +P S PP A+++ P +
Sbjct: 639 PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP-EASRLSPPPED-- 695
Query: 735 ETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAK 794
+P SP P SPPP+ L +PLE S L
Sbjct: 696 -SPTSPPPEDSPASPPPE---------------------------DSLMSLPLEESPLLP 727
Query: 795 KRADLVEKVRREAEQRAREEKEREREREREKERE-REKERELERSVKLAQEGRAPVECPS 853
+ E + R E R E R +E L + P E P
Sbjct: 728 --------LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE-PC 778
Query: 854 LGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDP 913
L VP P P + P+L P L + PH +SP VP +P
Sbjct: 779 LCAVPEEPHLSPQAE----GPHLSPQPEELHLSPQTEEPH-LSP--------VP---EEP 822
Query: 914 GLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPR 973
L P S + + E R L P E P P PG P P
Sbjct: 823 CLS----PQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE 878
Query: 974 HGGLALQPGPPGLHPF--------PFHPSLGPLERE-RLALAAGPALRPDM 1015
L PG P L P P P L PL E L+ + P+L P +
Sbjct: 879 ELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929
Score = 82.0 bits (201), Expect = 3e-15
Identities = 282/1222 (23%), Positives = 390/1222 (31%), Gaps = 235/1222 (19%)
Query: 71 GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130
G S + E + EE A + L SPS L G L + D R+
Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELK---TPDVFKAPLTPRA 2335
Query: 131 TSPSIYSPGSVENDSDSSSGLSQGPARPYHP--------------PPLFP-PSPQPPDST 175
+ SPG + + P+ P HP PPL P P P PP+S
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395
Query: 176 PRQPEASFEPHP----SVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGP 231
P S P +P + P T R A P P + + S P
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ--SPDPYSRP 2453
Query: 232 PMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP- 290
P P+ P PP P V+ S A T +G G P+A P
Sbjct: 2454 PSRPQSRD-------PFAPLHKPPRPQPPEVAFKAGSLAH------TSLGAGGFPAALPA 2500
Query: 291 -PANFPHV-TPNLPPPPALRPLNNASASPPGLGA---QPLPGHLPSPHAMGQGMGGLPPG 345
PA H P+ PP +R PG GA P P P A+G+ PP
Sbjct: 2501 GPAGELHAKVPSGQPPNFVRS--------PGTGAFVGTPSPMRFTFPQAVGEP-SLKPPV 2551
Query: 346 PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSS----------SSSSAAASSSSSSSSSS 395
P+ G P PH + S P P + P S++ S S SS S+ S
Sbjct: 2552 PQPG---LPPPHGIN--SHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYG 2606
Query: 396 ASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANS 455
SP LP PP S+ +Q S + V + P G LA +
Sbjct: 2607 LSPLRPPSVLP------PPAPDGSLPYLSHGASQRSGITSPV-EKREDPGTGMGSSLATA 2659
Query: 456 NAHPGPFPPSTGAQSTAHPPVSTHHHHHQ---QQQQQQQQQQQQQQQQQQHHGNSGPPPP 512
P +G T + +QQ Q+ +Q+++ G GPP
Sbjct: 2660 ELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGS 2719
Query: 513 -GAFPH-PLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP--PPHSQVSYSQAGPNGPPV 568
GA P P S P+A + SL PP P P S S + PP
Sbjct: 2720 WGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPA 2779
Query: 569 SSSS----------NSSSSTSQGSYPCSHPSPSQGPQ-----------------GAPYPF 601
+ SS S + + YP S P Q Q A +P
Sbjct: 2780 TPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPS 2839
Query: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASP-PGPPPYGKRAPSP----------GAYK 650
P P + + + S AG T P PG P G P+ G
Sbjct: 2840 TPGPELGRQA---------LGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGP 2890
Query: 651 TATP-PGYKPGSPPSFRTGT-------PPGYRGTS----PPAGPGTFKPGSPTVGPG--P 696
TP PG P P F + P G RG + PP P P +P + P
Sbjct: 2891 GGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSA--PPAPELNNSLHP 2948
Query: 697 LP----PAGPSGLPSLPPPPAAPASGPPLS-ATQIKQEPAEEYETPESPVPPARSPSPPP 751
P P P+GL + PP++ G P A + + P E+ E +
Sbjct: 2949 TPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDD------------- 2995
Query: 752 KVVDVPSH-ASQSARFNKHLDRGFNSCARSDLYFVPLEGSK---------LAKKRADLVE 801
D +H A + HL G + A+ D LE + L DL+
Sbjct: 2996 ---DFDAHKALEDDEELAHLGLGVD-VAKGDDELGTLENLETNDPHLDDLLNGDEFDLLA 3051
Query: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861
E + +++ E R E E+ + L R V+ P P P
Sbjct: 3052 YTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRGVE---------------PGPLGP 3096
Query: 862 PFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHP--FYVPLGAVDPGLLGYN 919
P PP P L ++ +P V G P F + V+P
Sbjct: 3097 EERP-------PPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEP------ 3143
Query: 920 VPALYSSDPAAREREREARERDLRDRLKP----GFEVKPSELEPLHGVPGPGLDPFPRHG 975
PA S + + RD R P G + + G P L P P G
Sbjct: 3144 APAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSG 3203
Query: 976 GLALQPGPPGLHPFPFHPSLGPLERERLALAAGPAL---RPDMSYAERLAAERQ-HAERV 1031
PG L LE L L GPA D + +A+E E +
Sbjct: 3204 -----PGGSSL------LEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDL 3252
Query: 1032 AALGNDPLARLQMLN--VTPHHHQHSHIHSHLHLHQQDAIHAASASVHPLIDPLASGSHL 1089
L + Q L+ + P Q H L A S H P +GS
Sbjct: 3253 LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLP-HEGSSPSLAGSQ- 3310
Query: 1090 TRIPYPAGTLPNPLLPHPLHENEVLRHQLFAAPYRDLPASLSAPMSAAHQLQAMHAQSAE 1149
++ P LP PL + H L + L S++ + H L H A
Sbjct: 3311 QQLSLGLAGARQPGLPQPLMPTQPPAHAL----QQRLAPSMAMVSNQGHMLSGQHGGQAG 3366
Query: 1150 LQRLALEQQQWLHAHHPLHSVP 1171
L + + Q + + P+ ++P
Sbjct: 3367 L--VPQQSSQPVLSQKPMGTMP 3386
Score = 81.3 bits (199), Expect = 5e-15
Identities = 183/792 (23%), Positives = 244/792 (30%), Gaps = 149/792 (18%)
Query: 236 KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFP 295
+GG SV +QH P + S G + P +P V P
Sbjct: 353 QGGQTIRSVA-----EQHTPVCSRFSPPEPGDT--PTDEPDALYVACQGQPKGG------ 399
Query: 296 HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP- 354
HVT P P PL A P G L L +P + + M LPP PE+ P P
Sbjct: 400 HVTSMQPKEPG--PLQ-CEAKPLGKAGVQLEPQLEAP--LNEEMPLLPP-PEESPLSPPP 453
Query: 355 --SPHSLPPASSSAPAPPMRFPYS------------SSSSSSAAASSSSSSSSSSASPF- 399
SP S PP +S PP P S S S S S +SPF
Sbjct: 454 EESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS 513
Query: 400 PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP-------PPPPYGRLL 452
P ++ S P PP +L PP P P PP PPP RL
Sbjct: 514 PLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS 573
Query: 453 ANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPP 512
P PP S PP ++ ++ ++ PPP
Sbjct: 574 PPPEESPMSPPPEESPMSP--PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPE 631
Query: 513 GA--FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSS 570
+ P P E P + P + L P P PPP + P PP
Sbjct: 632 DSPMSPPPEES-------PMSPPPEVSRLSPLPVVSRLSPPP-------EESPLSPPPEE 677
Query: 571 SSNSSSSTSQGSYPCSHPSP-SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK 629
S S + P SP S P+ +P PP ++ + S ++
Sbjct: 678 SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL--------- 728
Query: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS 689
P P R+ P P P R P P +
Sbjct: 729 ----PEEPQLCPRSEGPHLSPRPEEPHLSP--------------RPEEPHLSP---QAEE 767
Query: 690 PTVGPGPLPPAGPSGLPSLPPPP--AAPASGPPLSATQIKQEPAEEYETPE-SPVPPARS 746
P + P P P L ++P P + A GP LS + + + E P SPVP
Sbjct: 768 PHLSPQPEEPC----LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823
Query: 747 PSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRRE 806
SP P+ SH S + R S +L PL
Sbjct: 824 LSPQPE----ESHLSPQSEEPCLSPRPEESHLSPELEKPPLS------------------ 861
Query: 807 AEQRAREEKEREREREREKERER---EKERELERSVKLAQEGRAPVECPSLGPVPHRPPF 863
R EK E + E E S L + + P L P+P P
Sbjct: 862 ----PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPL 917
Query: 864 EPGSAVATVPPYLGPD--TPALRTLSEYARPHVMSP-GNRNHPFYVPLGAVDPGLLGYNV 920
P + P + PD P L + A P +SP G +PF G G +
Sbjct: 918 SPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPF---------GAKGDSD 968
Query: 921 PALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQ 980
P + P E + D P + P+ P PG P + ++
Sbjct: 969 PESPLAAPILETPISPPPEANCTD---------PEPVPPMILPPSPG-SPVGPASPILME 1018
Query: 981 PGPPGLHPFPFH 992
P PP P H
Sbjct: 1019 PLPPQCSPLLQH 1030
Score = 68.2 bits (165), Expect = 5e-11
Identities = 129/514 (25%), Positives = 164/514 (31%), Gaps = 62/514 (12%)
Query: 517 HPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSS 576
H +GG + + +P P PG P + Q P G V+S
Sbjct: 350 HKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP 409
Query: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP-- 634
Q + P G Q P P+ L + S P SPP
Sbjct: 410 GPLQCE---AKPLGKAGVQLEPQLEAPL---NEEMPLLPPPEESPLSPPPEESPTSPPPE 463
Query: 635 ----GPPPYGKRA-PSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP-- 687
PPP A P P A + P P SPP P SPP F P
Sbjct: 464 ASRLSPPPEELPASPLPEALHLSRPLEESPLSPP-------PEESPLSPPPESSPFSPLE 516
Query: 688 GSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSP 747
SP P PP+ P PPP A+P S PP + + P E P SP P A
Sbjct: 517 ESPLSPPEESPPSPALETPLSPPPEASPLS-PPFEESPLSPPPEE---LPTSPPPEASRL 572
Query: 748 SPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREA 807
SPPP+ + +S + + F P E S L+ + EA
Sbjct: 573 SPPPEESPMSPPPEESP---------MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623
Query: 808 EQRAREEKEREREREREKEREREKERELERSVKLAQEGRA--PVECPSLGPVPHRPPFEP 865
+ + ++ E E E+ R L R P E L P P P P
Sbjct: 624 SRLSPPPEDSPMSPPPE-ESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682
Query: 866 GSAVATV--PPYLGPDTPALRTLSEYARPH--VMSPGNRNHPFYVPLGAVDPGLLGYNVP 921
+ + PP P +P P +MS P +PL +P L P
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL-LPLPE-EPQLC----P 736
Query: 922 ALYSSDPAAREREREARERDLRDRLKPGFE---VKPSELEP-LHGVP----------GPG 967
+ R E R L P E + P EP L VP GP
Sbjct: 737 RSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPH 796
Query: 968 LDPFPRHGGLALQPGPPGLHPFPFHPSLGPLERE 1001
L P P L+ Q P L P P P L P E
Sbjct: 797 LSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830
Score = 65.1 bits (157), Expect = 4e-10
Identities = 116/447 (25%), Positives = 141/447 (31%), Gaps = 122/447 (27%)
Query: 331 SPHAMGQGMGGLPPGPE-KGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS 389
+P +M G + P L P P SS PP+R P S ++
Sbjct: 4054 TPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
Query: 390 SSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP------P 443
S S +S S PH P S+S+ +QP TQ L Q + P P
Sbjct: 4114 GSHGQLGSG--SSSEASSVPHLLAQP-SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGP 4170
Query: 444 PPPPYGRLLANSNAHPGP-FPPSTG---AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499
PP G +L + PG P+ G AQ + H QQQQQ Q Q+Q
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230
Query: 500 QQQHHGNSGPPP---PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQV 556
QQ PP PG PL+G P LG PGP
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQG-------LLGCQPQLGGF----PGP---------- 4269
Query: 557 SYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLST 616
Q GP G P QGP P P P ++ L
Sbjct: 4270 ---QTGP-----------LQELGAGPRP-------QGPPRLPAP----PGALSTGPVLGP 4304
Query: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT 676
V P PPP + P +P PS + P
Sbjct: 4305 V---------------HPTPPPSSPQEPK------------RPSQLPSPSSQLPT--EAQ 4335
Query: 677 SPPAGPGTFKPGSPTVGPGP--LPPA-------------GPSGLP------------SLP 709
PP PGT KP PT+ P P + PA GP P SL
Sbjct: 4336 LPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLV 4395
Query: 710 PPPAAPASG---PPLSATQIKQEPAEE 733
P +G P S IKQEP EE
Sbjct: 4396 PGHLDQVNGQVVPEASQLSIKQEPREE 4422
Score = 58.5 bits (140), Expect = 4e-08
Identities = 105/397 (26%), Positives = 124/397 (31%), Gaps = 146/397 (36%)
Query: 484 QQQQQQQQQQQQQQ-------------QQQQQHHGNSGP----------PPPGAFPHPL- 519
QQQQQ QQQQQQQQ QQQQQ GP PGA L
Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLL 4020
Query: 520 ------------------EGGSSHHAHPYAMS--------------PSLGS------LRP 541
EG S+H P A+ PSL ++P
Sbjct: 4021 LTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQP 4080
Query: 542 YP---PGPAHLPPP-------HSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS 591
P P L PP QVS G S SSS S + + PS S
Sbjct: 4081 QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVS 4140
Query: 592 QGPQGAPY---------------------PFPP-----------------VPTVTTSSAT 613
G Q P PP +PTV A
Sbjct: 4141 LGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ 4200
Query: 614 LSTVIATVASSPAGYKTASPPGPPPYG----KRAPSPGAYKTATPPGYKPGSPPSFRTGT 669
L V+A +P + SP +R TPP +PG+ +T
Sbjct: 4201 LQGVLA---KNPQ-LRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGT----QTSP 4252
Query: 670 PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG----PSGLPSLPPPPAAPASGPPLSATQ 725
G G P G G P GPL G P G P LP PP A ++GP L
Sbjct: 4253 LQGLLGCQPQLG------GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG--- 4303
Query: 726 IKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQ 762
P P PP SP P + +PS +SQ
Sbjct: 4304 -----------PVHPTPPPSSPQEPKRPSQLPSPSSQ 4329
Score = 53.1 bits (126), Expect = 2e-06
Identities = 218/993 (21%), Positives = 321/993 (32%), Gaps = 204/993 (20%)
Query: 246 GPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPP 305
GP G ++ PPP S AS P KP GG PS P F TP + P P
Sbjct: 3092 GPLGPEERPPPAADASEPRL-ASVLPEVKPKVEE--GGRHPS---PCQFTIATPKVEPAP 3145
Query: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
A L GLG +P GQ M G S
Sbjct: 3146 AANSL--------GLGLKP-----------GQSMMG-----------------------S 3163
Query: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPP 425
P+SSS ++ AS ++ P + L P S P +SL +
Sbjct: 3164 RDTRMGTGPFSSSGHTAEKASFGATGG-------PPAHLLTPSPLSGPGGSSLLEKFE-- 3214
Query: 426 KYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485
L S A+ G P A S S A P + H++
Sbjct: 3215 ------LESGALTLPGGP---------AASGDELDKMESSLVASEL--PLLIEDLLEHEK 3257
Query: 486 QQQQQQQQ--------QQQQQQQQQHHGNSGPPPPGAFPHPLEGGS-SHHAHPYAMSPSL 536
++ Q++QQ QQQQQQQQQH S P P A P EG S S +S L
Sbjct: 3258 KELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGL 3317
Query: 537 -GSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGS-----YPCSHPSP 590
G+ +P P P P + + P+ VS+ + S G S P
Sbjct: 3318 AGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVL 3377
Query: 591 SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPPYGKRAPSPGAY 649
SQ P G PP + + +A K A+ P K
Sbjct: 3378 SQKPMGT---MPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKA------- 3427
Query: 650 KTATPPGYKPGSPPSFRTGTPPGYR-------GTSPPAGPGTFKPGSPTVGPGPLPPAGP 702
K G K G PG GP + G G AG
Sbjct: 3428 KMVALKGIKKVMAQG-SIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAG- 3485
Query: 703 SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD--VPSHA 760
P+ P PP A + E A++ + E + KV++ + H
Sbjct: 3486 --------DPSQPRPNPPTFAQGVINE-ADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHR 3536
Query: 761 SQ------SARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREE 814
R K R F L V + SK+ +K+ D V K ++E E
Sbjct: 3537 KSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKI-QKQLDQVRKQQKEHTNLMAEY 3595
Query: 815 KEREREREREKEREREKERELERSVKLAQEGRAPVECP-------SLGPVPHRPPFEPGS 867
+ +++++++++++++++ + ++ +Q R + P L P P PP
Sbjct: 3596 RNKQQQQQQQQQQQQQQHSAV-LALSPSQSPRLLTKLPGQLLPGHGLQP-PQGPPGGQAG 3653
Query: 868 AVATVPPYLG----PDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPAL 923
+ P + P P L T + S G + P G PG L AL
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGS--LAGPSGGFFPGNL-----AL 3706
Query: 924 YSSDPAAR---EREREARER--DLRDRLKPGFEVKPSELEPLHGV-------PGPGLDPF 971
S P +R ER+ + +++ L +L+ + + + L V GPG+
Sbjct: 3707 RSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQT- 3765
Query: 972 PRHGGLALQPGPPGLHPFPFHPS-----------------LGPLERERLALAAGPALRPD 1014
AL P P GL P H LGP + L AL P
Sbjct: 3766 ----NQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQ 3821
Query: 1015 MSYAE------RLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHLHQQDA 1068
+ + R+ + Q A++ L L Q H Q + HL Q
Sbjct: 3822 GPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLM 3881
Query: 1069 IHAASASVHPLIDPLASGSHLTRIPYPAGTLPNPLLPHPLHENEVL--RHQLFAAPYRDL 1126
H+ + P G+L L + + L + Q + L
Sbjct: 3882 SHSGQPKLS---------------AQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQL 3926
Query: 1127 PASLSAPMSAAHQLQAMHAQSAELQRLALEQQQ 1159
QLQ Q + Q+ L+QQQ
Sbjct: 3927 QQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQ 3959
Score = 53.1 bits (126), Expect = 2e-06
Identities = 189/872 (21%), Positives = 265/872 (30%), Gaps = 176/872 (20%)
Query: 10 MSMRSGRKKEAPGPREELRSRGRASPG-GVSTSSSDGKAEKSRQTAKKARVEEASTPKVN 68
M +G + PGP + G+ PG G+ + +A+ AK ++ S +
Sbjct: 4164 MQNNTGPQPPKPGP---VLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQ-- 4218
Query: 69 KQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDN 128
+Q + + + +++ A ++T QE SP L L G G P+
Sbjct: 4219 QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP--LQGLLGCQPQLGGFPGPQTGPLQE 4276
Query: 129 RSTSPSIYSPGSVENDSDS-SSGLSQGPARPYHPPPLFPPSPQPPDSTPRQP-----EAS 182
P P + + S+G GP P PPP P P+ P P EA
Sbjct: 4277 LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPT-PPPSSPQEPKRPSQLPSPSSQLPTEAQ 4335
Query: 183 FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTG--------GVLSGPPMG 234
P TP +EPP R+ P A L+ G G P
Sbjct: 4336 LPPTHPGTPKPQGPTLEPPPGRV---SPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQS 4392
Query: 235 PKGGGAASSVGG---PNGGK---QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288
G V G P + + P P ++ + +P P +L A
Sbjct: 4393 SLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLA 4452
Query: 289 PPPANFPHVTPNLPPPPALRPLN---NASASPPGLGAQPLPGHLPSPHA-MGQGMGGLPP 344
P + H L LR N + GL A+ + GH+ S A + Q + G P
Sbjct: 4453 GPRSEAGH----LLLQKLLRAKNVQLSTGRGSEGLRAE-INGHIDSKLAGLEQKLQGTPS 4507
Query: 345 GPEKGPT---LAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
E L P P + AS + + A+ + S P
Sbjct: 4508 NKEDAAARKPLTPKPKRVQKASDRLVSSRKKL---RKEDGVRASEALLKQLKQELSLLPL 4564
Query: 402 SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP 461
++ + S P + + S A+ P P Y +LL +N P
Sbjct: 4565 TEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGAL----PTGPDYYSQLLTKNNLSNPP 4620
Query: 462 FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521
PPS+ + PP S QQ N P HP +
Sbjct: 4621 TPPSSLPPT---PPPSV----------------------QQKMVNGVTPSEELGEHPKDA 4655
Query: 522 GSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG 581
S+ + S ++ A PPH+Q V S+ S +
Sbjct: 4656 ASARDSERALRDTS--EVKSLDLLAALPTPPHNQTE---------DVRMESDEDSDSPDS 4704
Query: 582 SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA---------SSPAGYKTAS 632
P S P G + +P LS VI + + P G
Sbjct: 4705 IVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLE 4764
Query: 633 PPGPPPY-----GKRAP-------SPGAYKTAT--------------PPGYKPGSPPS-F 665
PG P GK + S A K P Y+ P S
Sbjct: 4765 VPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPA 4824
Query: 666 RTGTPP-------------GYRGTSPPAGPGTFK------PG------------SPTVGP 694
R GT P G G SP GP K PG P
Sbjct: 4825 RAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESP 4884
Query: 695 GPLPP------------------AGPSGLPSLPPPPAA--PASGPPLSATQIKQEPAEEY 734
P PP A P PS PP P A PAS P ++ EP E
Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944
Query: 735 ETPESPVPPARSP-SPPPKVVDVPSHASQSAR 765
P SP+P A SP S PK P + +R
Sbjct: 4945 PVP-SPLPLASSPESARPKPRARPPEEGEDSR 4975
Score = 45.8 bits (107), Expect = 2e-04
Identities = 77/333 (23%), Positives = 97/333 (29%), Gaps = 59/333 (17%)
Query: 178 QPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKG 237
QP S P P +P R Q G PP P G VL G G
Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKP-------GPVLQS-GQGLPG 4187
Query: 238 GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHV 297
G +VG + G P +P L +
Sbjct: 4188 VGIMPTVG-------------QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQS 4234
Query: 298 TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
PP P S LG QP +GG PGP+ GP
Sbjct: 4235 QAVRQTPPYQEPGTQTSPLQGLLGCQP-------------QLGGF-PGPQTGPLQELGAG 4280
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
P PAPP A S+ +P P+S P P P P+S
Sbjct: 4281 PRPQGPPRLPAPP------------GALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Query: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL------LANS--NAHPGPFPPSTGAQ 469
+ T P P QGP PP GR+ LA++ + GP+ P
Sbjct: 4329 QLPTEAQLPPTHPGTPK----PQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
Query: 470 STAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQ 502
T P S+ H Q Q + Q +Q
Sbjct: 4385 ETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQ 4417
Score = 41.2 bits (95), Expect = 0.006
Identities = 73/340 (21%), Positives = 111/340 (32%), Gaps = 56/340 (16%)
Query: 31 GRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKT 90
G PG S ++ + ++ RQ ++ + + +Q +E + + + P
Sbjct: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQ--EKETAAAAAGAVGPPGSW 2720
Query: 91 KTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRD-IDQDNRSTSPSIYSPGSVENDSDSSS 149
E P SP+ + L G+ D + S I PGS +D S
Sbjct: 2721 GAE-----PSSPA-FEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLS- 2773
Query: 150 GLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP 209
PPP P +P D RQ + P P++ +++Q
Sbjct: 2774 ----------RPPP--PATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQ 2821
Query: 210 PGAPPPHPQL-----YPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTP---IS 261
+ +P G L +G G ++ + GP G+ P P P I
Sbjct: 2822 QATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGP--GEPVPGPAGPAQFIE 2879
Query: 262 VSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLG 321
+ + G P GG P PP P P P L P GL
Sbjct: 2880 LRHNVQKGLGP--------GGTPFPGQGPPQR-PRFYPVSEDPHRLAP-----EGLRGLA 2925
Query: 322 AQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361
LP PS PP PE +L P+PH+ P
Sbjct: 2926 VSGLPPQKPSA----------PPAPELNNSLHPTPHTKGP 2955
Score = 37.7 bits (86), Expect = 0.066
Identities = 43/149 (28%), Positives = 52/149 (34%), Gaps = 23/149 (15%)
Query: 861 PPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVP------------- 907
PP P +T P+L P P+L L+ P V G + P P
Sbjct: 2230 PPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV-GGGKASEPLLSPPPFGESRKALEVK 2288
Query: 908 ---LGAVDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVP 964
LGA P Y P L D + E D K + S++EP P
Sbjct: 2289 KEELGASSP---SYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQS--P 2343
Query: 965 GPGLDPFPRHGGLALQPGPPGLHPFPFHP 993
G GL P AL P PP HP F P
Sbjct: 2344 GLGLRPQEPPPAQALAPSPPS-HPDIFRP 2371
Score = 36.6 bits (83), Expect = 0.15
Identities = 65/263 (24%), Positives = 87/263 (33%), Gaps = 42/263 (15%)
Query: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP 543
QQQQQQ QQQQQQ QQQQQ L S P +L P
Sbjct: 3942 QQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM 4001
Query: 544 PGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP---QGAPYP 600
P P H +S G GP + + ++ P ++GP QG P
Sbjct: 4002 PAK---PLQH----FSSPGALGPTLLLTGKEQNTVD----PAVSSEATEGPSTHQGGPL- 4049
Query: 601 FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATP---PGY 657
+ T+ +++T V S +G P P P P + + P PG
Sbjct: 4050 -----AIGTTPESMATEPGEVKPSLSGDSQLLLVQPQP----QPQPSSLQLQPPLRLPGQ 4100
Query: 658 KPGSPPSFRTGTPPGY----RGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGL-----PSL 708
+ T + G+S A P+V G P + L P L
Sbjct: 4101 QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPML 4160
Query: 709 PPP------PAAPASGPPLSATQ 725
P P P GP L + Q
Sbjct: 4161 ERPMQNNTGPQPPKPGPVLQSGQ 4183
Score = 36.6 bits (83), Expect = 0.15
Identities = 44/174 (25%), Positives = 60/174 (34%), Gaps = 32/174 (18%)
Query: 316 SPPGLGAQPLPGHLPSPHAMGQGMGGLPP--GPE---------KGPTLAPSPH--SLPPA 362
SP G +P G P +G+ G P GP+ G TL SL
Sbjct: 4822 SPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQ 4881
Query: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN 422
S AP PP + Y+ + S+ S+ P PPP+ L+ S
Sbjct: 4882 ESPAPEPPTQHSYTYNVSNLDVRQLSA----------------PPPEEPSPPPSPLAPSP 4925
Query: 423 -QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475
PP LP++ + P P P ++ P PP G S PP
Sbjct: 4926 ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDS--RPP 4977
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/95 (33%), Positives = 33/95 (34%), Gaps = 16/95 (16%)
Query: 671 PGYRGTSPPAGPGTFKPGSPTVGPG--------PLPPAGPSGLPSLPP------PPAAPA 716
PG G+ PPA T GSPT G PPAG P P PP PA
Sbjct: 2110 PGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPA 2169
Query: 717 SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
P S PA E PP P P P
Sbjct: 2170 QVP--SQDPFGLAPAYPLEPRFPTAPPTYPPYPSP 2202
Score = 32.3 bits (72), Expect = 2.8
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 10/70 (14%)
Query: 255 PPTTPISVSSSGASGAPPTKP----PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL 310
PP +P++ S + +PPT+P PT P+ +PS P A+ P P P A P
Sbjct: 4916 PPPSPLAPSPA----SPPTEPLVELPTEPLAEPPVPSPLPLASSPESA--RPKPRARPPE 4969
Query: 311 NNASASPPGL 320
+ PP L
Sbjct: 4970 EGEDSRPPRL 4979
Score = 30.8 bits (68), Expect = 8.0
Identities = 21/64 (32%), Positives = 25/64 (39%), Gaps = 1/64 (1%)
Query: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736
SPP P P SP P P P P + P P AS P + + + P EE E
Sbjct: 4915 SPPPSPLAPSPASPPTEPLVELPTEPLAEPPV-PSPLPLASSPESARPKPRARPPEEGED 4973
Query: 737 PESP 740
P
Sbjct: 4974 SRPP 4977
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 114 bits (285), Expect = 6e-25
Identities = 138/480 (28%), Positives = 160/480 (33%), Gaps = 99/480 (20%)
Query: 134 SIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTG 193
++ S ++ D S P PP PQ P S P +P+ P G
Sbjct: 12 ALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP-------PPQG 64
Query: 194 YHAPMEPPTSRMFQAPPGAPP-PHPQLYPGGTGGVLSGPPMGPKGGGAAS-SVGGPNGGK 251
+ P PP PPG P P PQ G G P GP G S S P G
Sbjct: 65 GNQPQGPP------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 118
Query: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
Q PPP + PP KP P GGN P PPP P PPP +
Sbjct: 119 QGPPPQ---GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ-----GPPPQGDNKS 170
Query: 312 NASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPM 371
+S SPPG P P QG G P GP P P PP + P P
Sbjct: 171 RSSRSPPGKPQGPPP----------QG-GNQPQGPPPPP---GKPQGPPPQGGNKPQGP- 215
Query: 372 RFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS 431
+ S S+ SP P P PPP NQP
Sbjct: 216 ----PPPGKPQGPPPQGDNKSQSARSP-------PGKPQG-PPPQG---GNQP------- 253
Query: 432 LPSQAVWSQGPPPPP--PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
QGPPPPP P G N GP PP G P + + +
Sbjct: 254 --------QGPPPPPGKPQGPPPQGGNKPQGPPPP--GKPQGPPPQGGSKSRSSRSPPGK 303
Query: 490 QQQQQQQQQQQQQHHGNSGPPPPGAFPH--PLEGGSSHHAHPYAMSPSLGSLRPYPPGPA 547
Q Q Q Q GPPPP P P +GG+ P PPG
Sbjct: 304 PQGPPPQGGNQPQ-----GPPPPPGKPQGPPPQGGNKPQGPP-------------PPGKP 345
Query: 548 HLPPPH----SQVSYSQAG-PNGPPVSSSSN-SSSSTSQGSYPCSHPSPSQG-PQGAPYP 600
PPP S+ + S G P GPP +N G P +P G PQG P P
Sbjct: 346 QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405
Score = 107 bits (267), Expect = 7e-23
Identities = 147/508 (28%), Positives = 164/508 (32%), Gaps = 137/508 (26%)
Query: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA 322
S S +G P PP GGN P PP P P PPP N PP
Sbjct: 28 SPSLIAGNPQGAPPQ----GGNKPQGPPS---PPGKPQGPPPQG----GNQPQGPP---- 72
Query: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS 382
P PG P G G P GP PP P P
Sbjct: 73 -PPPGKPQGPPPQG---GNKPQGPP------------PPGKPQGPPP------------- 103
Query: 383 AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGP 442
S S SP P P PPP NQP QGP
Sbjct: 104 -----QGDKSRSPRSP-------PGKPQG-PPPQG---GNQP---------------QGP 132
Query: 443 PPPP--PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQ 500
PPPP P G N GP PP + PP + + + Q Q
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189
Query: 501 QQHHGNSGPPPPGAFPH--PLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH----S 554
Q GPPPP P P +GG+ P PPG PPP S
Sbjct: 190 QPQ----GPPPPPGKPQGPPPQGGNKPQGPP-------------PPGKPQGPPPQGDNKS 232
Query: 555 QVSYSQAG-PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQG--PQGAPYPFPPV-PTVTTS 610
Q + S G P GPP + P P P G PQG P P P P
Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKP-QGPPPQGGNKPQGPPPPGKPQGPPPQGG 291
Query: 611 SATLSTVIATVASSPAGYKTASPPGPPPYG---KRAPSPGAYKTATPP---GYKPGSPPS 664
S + S+ SP G P GPPP G + P P K PP G KP PP
Sbjct: 292 SKSRSS------RSPPG----KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP- 340
Query: 665 FRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSAT 724
PPG PP G + G PP P PPP PA G P
Sbjct: 341 -----PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP---PAGGNP---Q 389
Query: 725 QIKQEPAEEYETPESPVPPARSPSPPPK 752
Q + PA + + P P P PS PP+
Sbjct: 390 QPQAPPAGQPQGPPRP-PQGGRPSRPPQ 416
Score = 105 bits (263), Expect = 2e-22
Identities = 128/475 (26%), Positives = 159/475 (33%), Gaps = 115/475 (24%)
Query: 119 SDPRDIDQD-NRSTSPSIYS---PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDS 174
S +++++D ++ SPS+ + G+ + G P +P PPP PQ P
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP 73
Query: 175 TPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPG---------APPPHPQLYPGGTG 225
P +P+ P G + P PP Q PP +PP PQ P G
Sbjct: 74 PPGKPQGP-------PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 126
Query: 226 GVLSGPP------MGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP---- 275
GPP GP G G P GK PP P + S +S +PP KP
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP--PQGDNKSRSSRSPPGKPQGPP 184
Query: 276 -------------PTTPVG----GGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPP 318
P P G GGN P PPP P PPP + ++ SPP
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ-----GPPPQGDNKSQSARSPP 239
Query: 319 GLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSS 378
G P P QG G P GP P P PP + P P
Sbjct: 240 GKPQGPPP----------QG-GNQPQGPPPPP---GKPQGPPPQGGNKPQGP-----PPP 280
Query: 379 SSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVW 438
S S SS SP P P PPP NQP
Sbjct: 281 GKPQGPPPQGGSKSRSSRSP-------PGKPQG-PPPQG---GNQP-------------- 315
Query: 439 SQGPPPPP--PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQ 496
QGPPPPP P G N GP PP + PP + + + + Q
Sbjct: 316 -QGPPPPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPP----QGGSKSRSARSPPGKPQ 367
Query: 497 QQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPP 551
QQ+ + GPPPP GG+ G RP G PP
Sbjct: 368 GPPQQEGNNPQGPPPPA-------GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 105 bits (261), Expect = 3e-22
Identities = 111/396 (28%), Positives = 131/396 (33%), Gaps = 74/396 (18%)
Query: 380 SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN--QPPKYTQPSLPSQAV 437
S + A SS+ + + S + + P PP PP Q P
Sbjct: 7 SVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGN 66
Query: 438 WSQGPPPPP--PYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQ 495
QGPPPPP P G N GP PP + PP + + Q
Sbjct: 67 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGDKSRSPRSPPGKPQGPPP 123
Query: 496 QQQQQQQHHGNSGPPPPGAFPH--PLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH 553
Q Q Q GPPPP P P +GG+ P PPG PPP
Sbjct: 124 QGGNQPQ-----GPPPPPGKPQGPPPQGGNKPQGPP-------------PPGKPQGPPPQ 165
Query: 554 ----SQVSYSQAG-PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF------P 602
S+ S S G P GPP G+ P P P PQG P P
Sbjct: 166 GDNKSRSSRSPPGKPQGPPPQG----------GNQPQGPPPPPGKPQGPPPQGGNKPQGP 215
Query: 603 PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG---KRAPSPGAYKTATPP---G 656
P P + A SP G P GPPP G + P P K PP G
Sbjct: 216 PPPGKPQGPPPQGDNKSQSARSPPG----KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 271
Query: 657 YKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPA 716
KP PP PPG PP G + G PP P PPPP
Sbjct: 272 NKPQGPP------PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325
Query: 717 SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPK 752
GP P + P+ P PP + PPP+
Sbjct: 326 QGP----------PPQGGNKPQGPPPPGKPQGPPPQ 351
Score = 75.1 bits (183), Expect = 4e-13
Identities = 71/233 (30%), Positives = 81/233 (34%), Gaps = 55/233 (23%)
Query: 541 PYPPGPAHLPPPHSQVSYSQAG--PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAP 598
P PPG PPP Q G P GPP G+ P P P + PQG P
Sbjct: 51 PSPPGKPQGPPP-------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPP 102
Query: 599 YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYG---KRAPSPGAYKTATPP 655
P S + SP G P GPPP G + P P K PP
Sbjct: 103 ------PQGDKSRSP---------RSPPG----KPQGPPPQGGNQPQGPPPPPGKPQGPP 143
Query: 656 ---GYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPP 712
G KP PP PPG PP G + G PP P PPPP
Sbjct: 144 PQGGNKPQGPP------PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 197
Query: 713 AAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSAR 765
GP P + P+ P PP + PPP+ + SQSAR
Sbjct: 198 PGKPQGP----------PPQGGNKPQGPPPPGKPQGPPPQ----GDNKSQSAR 236
Score = 69.3 bits (168), Expect = 2e-11
Identities = 63/204 (30%), Positives = 75/204 (36%), Gaps = 49/204 (24%)
Query: 568 VSSSSNSSSSTSQGSYPCSHPSPSQG--PQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625
+SS+ N + SQ P QG PQG P P SP
Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGP-------------------PSP 53
Query: 626 AGYKTASPPGPPPYG---KRAPSPGAYKTATPP---GYKPGSPPSFRTGTPPGYRGTSPP 679
G P GPPP G + P P K PP G KP PP PPG PP
Sbjct: 54 PG----KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP------PPGKPQGPPP 103
Query: 680 AGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES 739
G + P SP P PP G + PPPP P PP + P+
Sbjct: 104 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK-----------PQG 152
Query: 740 PVPPARSPSPPPKVVDVPSHASQS 763
P PP + PPP+ D S +S+S
Sbjct: 153 PPPPGKPQGPPPQ-GDNKSRSSRS 175
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 111 bits (277), Expect = 5e-24
Identities = 215/899 (23%), Positives = 297/899 (33%), Gaps = 218/899 (24%)
Query: 25 EELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEE-----ASTPKVNKQGRSEEISES 79
E+L + + D K +K + +K VEE A P K ++ + +
Sbjct: 523 EQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSN 582
Query: 80 ESEETNAPKKTK-------TEQELPRPQS-------PSDLDSLDGRSLN----------- 114
S++ AP K+K E++ +P S D++ L G L
Sbjct: 583 VSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREP 642
Query: 115 DDGSSDPRDIDQDNRSTSPSIY---------------SPGSVENDSDSSSGLSQGPARPY 159
+S+P +I+ D + PS P + + D + S +G +
Sbjct: 643 SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSE 702
Query: 160 HPPPLFPPSPQPPDS-TPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPP 215
S DS T P++ + HP +H +M QAP P PPP
Sbjct: 703 SESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHH---HHHHQQMQQAPAPVPQQPPP 759
Query: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
PQ P PP P+ +Q PPP P PP+ P
Sbjct: 760 PPQQPP---------PPPPPQ-------------QQQQPPPPPP-----------PPSMP 786
Query: 276 PTTPVGGGNLPSAPPP---ANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332
+ S+PPP P + P LP + P G QP+ HLP P
Sbjct: 787 QQAAPA---MKSSPPPFIATQVPVLEPQLP---------GSVFDPIGHFTQPIL-HLPQP 833
Query: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYS-SSSSSSAAASSSSSS 391
LPP + P + PH A S PA P S S+ AAA +
Sbjct: 834 E--------LPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA 885
Query: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
+ SP L P PP L +PP S+ Q Q P
Sbjct: 886 RPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP----- 940
Query: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQ-----QQQQQQQQQQQHHGN 506
P P PS QS PP+ H QQQ QQQ Q Q QQQH
Sbjct: 941 -------PTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ-- 991
Query: 507 SGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH----SQVSYSQAG 562
PPP P++ S+H P P G P+PP PPP QV
Sbjct: 992 --PPPRPVHLQPMQ-FSTHIQQP---PPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHS 1045
Query: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP-QGAPYPFPPVPTVTTSSATLSTVIATV 621
P S S+ + P SP Q + PP V L
Sbjct: 1046 PRHH--KSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL------- 1096
Query: 622 ASSPAGYKTASPPGPPPY----GKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
+ AS P P ++ SP P +P P + P +
Sbjct: 1097 -------RAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQR 1149
Query: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
P P G P + P P A PPP AP + KQEP
Sbjct: 1150 PEMKP--VDVGRPVIRP-PEQNA---------PPPGAP------DKDKQKQEP------- 1184
Query: 738 ESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRA 797
++P P K + + + S ++ KH P S AK +
Sbjct: 1185 -------KTPVAPKKDLKIKNMGSWASLVQKH----------------PTTPSSTAKSSS 1221
Query: 798 DLVEKVRREAEQRAREEK---------ERERERER-EKEREREKERELERSVKLAQEGR 846
D E+ RR A ++ EK E+E+ER R E+ R RE E LE++ + +E R
Sbjct: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEAR 1280
Score = 96.7 bits (239), Expect = 1e-19
Identities = 197/901 (21%), Positives = 294/901 (32%), Gaps = 187/901 (20%)
Query: 4 RQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEAS 63
++ K + S S K+ P P ++ P S + K + K+ + +
Sbjct: 571 KKTKKNNSSNSNVSKKEPAPM-------KSKPPPTYESEEEDKCKPMSYEEKRQLSLDIN 623
Query: 64 TPKVNKQGRSEEISESE--SEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDP 121
K GR I +S S + + P + + + E +P + +L+ L
Sbjct: 624 KLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 683
Query: 122 RDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEA 181
+D S+ +S E+ S+SSS S+ T P++
Sbjct: 684 EKVDVIAGSSKMKGFSSSESESSSESSSSDSED------------------SETEMAPKS 725
Query: 182 SFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPPHPQLYPGGTGGVLSGPPMGPKGG 238
+ HP +H +M QAP P PPP PQ P PP P+
Sbjct: 726 KKKGHPGREQKKHHHHHH---QQMQQAPAPVPQQPPPPPQQPP---------PPPPPQQ- 772
Query: 239 GAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPP---ANFP 295
+Q PPP P PP+ P + S+PPP P
Sbjct: 773 ------------QQQPPPPPP-----------PPSMPQQAAPA---MKSSPPPFIATQVP 806
Query: 296 HVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS 355
+ P LP + P G QP+ HLP P LPP + P +
Sbjct: 807 VLEPQLP---------GSVFDPIGHFTQPIL-HLPQPE--------LPPHLPQPPEHSTP 848
Query: 356 PHSLPPASSSAPAPPMRFPYSSSSSSS-AAASSSSSSSSSSASPFPASQALPSYPHSFPP 414
PH A S PA P S S+ AAA + + SP L P P
Sbjct: 849 PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQP 908
Query: 415 PTSLSVSNQPPK----------YTQ---------PSLPSQAVWSQGPPP--PPPYGRLLA 453
P L +PP Y Q P LPS V SQ PPP PPP+ +
Sbjct: 909 PQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQ 968
Query: 454 NSNAHPGPFPP---STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
P P PP Q PP H Q QQ Q QQ H P
Sbjct: 969 QLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPH------P 1022
Query: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSS 570
PPG P P + + SP PY G P + Q
Sbjct: 1023 PPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQM--------- 1073
Query: 571 SSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKT 630
S S T Q S P + P + A P P V + + I + S P +
Sbjct: 1074 -SQFQSLTHQ-SPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPI--IRSEP--FSP 1127
Query: 631 ASPPGPPPYGKRAPSPGAYKTATPPGYKP---GSP---PSFRTGTPPGYRGTSPPAGPGT 684
+ P PP + + +P P KP G P P + PPG +P
Sbjct: 1128 SLRPEPPKHPESIKAP--VHLPQRPEMKPVDVGRPVIRPPEQNAPPPG----APDKDKQK 1181
Query: 685 FKPGSPTVGPGPLPPAGPSGLPSL----PPPPAAPASGPPLSATQIKQEPAEEYETPESP 740
+P +P L SL P P++ A S Q ++ E+ E ++
Sbjct: 1182 QEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKAL 1241
Query: 741 VPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLV 800
A + + R D AR + A++R +
Sbjct: 1242 KAQAEH-------AEKEKERLRQERMRSREDEDALEQAR--------RAHEEARRRQEQQ 1286
Query: 801 EKVRREAEQRAREEK--------------------EREREREREKEREREKERELERSVK 840
++ R+E +Q+ +++ +++RE R++E+ER + + ++
Sbjct: 1287 QQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATID 1346
Query: 841 L 841
+
Sbjct: 1347 M 1347
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 37/196 (18%)
Query: 560 QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP---QGAPYPFPPVPTVTTSSATLST 616
+ G P VS+ N T+Q S P +P P Q P+PFP V T + T
Sbjct: 185 ETGTAKPGVSTVPN----TTQASTPPQTQTPQPNPPPVQATPHPFPAV----TPDLIVQT 236
Query: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT 676
+ TV P +T P P P AP+P ++ P P + G T
Sbjct: 237 PVMTVVP-PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
Query: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736
+P T+ P PP SLPP P G ++E + +
Sbjct: 296 TPT-----------TIDPIHEPP-------SLPPEPKTTKLGQ-------RRESSRPVKP 330
Query: 737 PESPVPPARSPSPPPK 752
P+ VP ++ P K
Sbjct: 331 PKKDVPDSQQHPAPEK 346
Score = 41.6 bits (96), Expect = 0.005
Identities = 39/136 (28%), Positives = 52/136 (38%), Gaps = 10/136 (7%)
Query: 166 PPSPQPPDSTPRQPEASFEPHPSVTP--TGYHAPMEPPTSRMFQAPPGAPP-PHPQLYPG 222
PP Q P P +A+ P P+VTP M + Q PP PP P P P
Sbjct: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP- 263
Query: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVG- 281
V S PP+ V G K+ TTP ++ + P +P TT +G
Sbjct: 264 APQPVQSHPPI---IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQ 320
Query: 282 --GGNLPSAPPPANFP 295
+ P PP + P
Sbjct: 321 RRESSRPVKPPKKDVP 336
Score = 40.8 bits (94), Expect = 0.008
Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 8/85 (9%)
Query: 683 GTFKPGSPTVG---PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPE- 738
GT KPG TV PP + P+ PP A P P ++ I Q P P+
Sbjct: 187 GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
Query: 739 ----SPVPPARSPSPPPKVVDVPSH 759
PVPP P P P V SH
Sbjct: 247 LQTPPPVPPQPQPPPAPAPQPVQSH 271
Score = 40.4 bits (93), Expect = 0.010
Identities = 35/118 (29%), Positives = 40/118 (33%), Gaps = 18/118 (15%)
Query: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA---------PMEPPTSRM 205
P +P PP PP PQPP + QP S P + TP P T
Sbjct: 243 PPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
Query: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263
PP PP P+ G S P PK S +QHP P VS
Sbjct: 303 IHEPPSL-PPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEKSSKVS 351
Score = 38.5 bits (88), Expect = 0.038
Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 20/115 (17%)
Query: 735 ETPESPVPPARSPS--PPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKL 792
+ PE PV SP+ PP KVV PS + S+ + D + +
Sbjct: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDD-----------SEEER 507
Query: 793 AKKRADLVEKVRREAEQRA-------REEKEREREREREKEREREKERELERSVK 840
A++ A+L E+++ EQ A + K++E++++ +K+ + +++ E+E + K
Sbjct: 508 AQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKK 562
Score = 35.4 bits (80), Expect = 0.33
Identities = 26/96 (27%), Positives = 37/96 (38%), Gaps = 15/96 (15%)
Query: 381 SSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQ 440
S+ ++ +S+ + +P P + + PH FP T + P P P Q
Sbjct: 194 STVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT---- 249
Query: 441 GPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476
PPP PP P P P QS HPP+
Sbjct: 250 -PPPVPP--------QPQPPPAPAPQPVQS--HPPI 274
Score = 35.0 bits (79), Expect = 0.42
Identities = 40/172 (23%), Positives = 63/172 (36%), Gaps = 18/172 (10%)
Query: 274 KPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333
KP + V S PP P PN PPP P + +P + P+ +P P
Sbjct: 190 KPGVSTVPNTTQASTPPQTQTPQ--PN-PPPVQATPHPFPAVTPDLIVQTPVMTVVP-PQ 245
Query: 334 AMGQGMGGLPPGPEKGPTLAPSP-HSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392
+ Q +PP P+ P AP P S PP ++ P P + + +++
Sbjct: 246 PL-QTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQP--------VKTKKGVKRKADTTT 296
Query: 393 SSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP 444
++ P +LP P + T L + + +P Q P P
Sbjct: 297 PTTIDPIHEPPSLPPEPKT----TKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
Score = 32.3 bits (72), Expect = 2.8
Identities = 33/114 (28%), Positives = 38/114 (33%), Gaps = 25/114 (21%)
Query: 471 TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPY 530
TA P VST + Q Q Q Q PPP A PHP
Sbjct: 188 TAKPGVSTVPNTTQASTPPQTQTPQPN-----------PPPVQATPHPFP---------- 226
Query: 531 AMSPSLGSLRPY----PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
A++P L P PP P PPP P PV S ++T Q
Sbjct: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ 280
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 108 bits (269), Expect = 4e-23
Identities = 205/847 (24%), Positives = 271/847 (31%), Gaps = 157/847 (18%)
Query: 24 REELRSRGRASPGGVSTSSSDGKAEKSRQTAK--------KARVEEASTPKVNKQGRSEE 75
R E + GR SP +S S + + + + A + VNK +
Sbjct: 120 RSEQKLPGR-SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 76 ISESESEETNAPKKTKT---EQELP----------RPQSPSDLDSLDGRS-LNDDG---- 117
IS+SE+ + KK K EQ P +P P GR L DG
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 118 --SSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYH--------------- 160
S P I T I P + L + +RP
Sbjct: 239 ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL 298
Query: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPP--TSRMFQAPPGAPPPHPQ 218
P P PP QP TP +P A H P P +P T + Q P PP
Sbjct: 299 PSPSKPPIQQP---TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP--- 352
Query: 219 LYPGGTGGVLSGPPMGPKGGGA--ASSVGGPNGGKQHPPPTT---PISVSSSGASGAPPT 273
+ P GT + PP P G A G + P P P V + A P
Sbjct: 353 VQPPGT----TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 274 KPPTTPVGGGNLPSAPPPANFPHV-TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332
KPPT VG + P A P + +P P P P+ QP PG +P+
Sbjct: 409 KPPTQQVG-----TPKPLAQQPGLQSPAKAPGPTKTPVQ-----------QPGPGKIPAQ 452
Query: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392
A GP K P+ P P PP PP + P S+ + S+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----GSAKPPSQQPGSTK 508
Query: 393 SSSASPFPASQALPSYPHSFPPPTSLSVSNQP-PKYTQPSLPSQAVWSQGPPPPPPYGRL 451
P PA + P P S PP+ S +P + P+ PS A S P G+
Sbjct: 509 PPPQQPGPAKPS-PQQPGSTKPPSQQPGSAKPSAQQPSPAKPS-AQQSTKPVSQTGSGKP 566
Query: 452 LANSNAHP-GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
L P PPS G T P +T ++ + Q P
Sbjct: 567 LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN 626
Query: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSS 570
PH E + G L P P P Q PV++
Sbjct: 627 -----PHLTEVKEWLCLNCQMKRALGGDLAPVPSSP-------------QPKLKTAPVTT 668
Query: 571 SS--NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY 628
+S + SS Q + P +P Q AP P P P V TL + A P
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV--KQPTLHGSPSAKAKQPPEA 726
Query: 629 KTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT------------------- 669
+ S P PP K P A KP P + T
Sbjct: 727 DSLSKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 670 -PPGYRGTSPPAGPGTFKPGS--PTVGPGPLP--------PAGPSGLPSLPPPPAAPASG 718
T+PP + KP P G P PA S + S P P +
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ 843
Query: 719 PPLSATQIKQEPAEEYETPESPVPPAR-----SPSPP----------PKVVDVPSHASQS 763
+ Q K+EP ++ +T SP P A+ SP+PP P P QS
Sbjct: 844 KQVDPVQKKEEP-KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Query: 764 ARFNKHL 770
RF+ +L
Sbjct: 903 RRFSLNL 909
Score = 96.7 bits (239), Expect = 1e-19
Identities = 188/860 (21%), Positives = 285/860 (33%), Gaps = 144/860 (16%)
Query: 37 GVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQ----GRSEEISESESEETNAPKKTKT 92
G+ S A +S +K ++ + PK + + GR + S+S T+ ++
Sbjct: 65 GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDT---FRS 121
Query: 93 EQELPRPQSPSDLDSLDGRSLND-----DGSSDPRDIDQDNRSTSPSI----YSPGSVEN 143
EQ+LP +SPS + + +S D S P + + N ++ S ++P + +
Sbjct: 122 EQKLPG-RSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 144 DSDSSS------------------GLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEP 185
DS++S G+ + P + P P+ P Q P P Q + + +
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPI--PKQQGPGRDPLQQDGTPKS 238
Query: 186 HPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG 245
S P + P T + Q P P P G +
Sbjct: 239 ISSQQPEKIKS-QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 246 GPNGGK---QHPPPTTPISVSSSGASGAP-PTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301
P+ K Q P P P + P P KPP P G + P P V P
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357
Query: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361
P +PL A G++ P P A+ Q PPG K P P P P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQ-----PPGVGKTPAQQPGPAKPPT 412
Query: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVS 421
P P + P S + A + + PA QA P S
Sbjct: 413 QQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG-----------KTS 460
Query: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481
Q T+P PSQ GP PPP PGP P +A PP
Sbjct: 461 AQQTGPTKP--PSQL---PGPAKPPPQ---------QPGPAKPPPQQPGSAKPP-----S 501
Query: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPP--------PPGAFPHPLEGGSSHHAHPYAMS 533
+ QQ + Q G++ PP P P P + + P + +
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Query: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP-----VSSSSNSSSSTSQGSYPCS-- 586
S L+P P+ PP + + V +N ++ T + CS
Sbjct: 562 GSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 587 --HPSP-----------------SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAG 627
+P+P + G AP P P P + T A ++T A SSP
Sbjct: 622 GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT--APVTTTSAVSKSSPQP 679
Query: 628 YKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT---PPGYRGTSPPAGPGT 684
+T+ K+ +P + P KP PP + T P + PP
Sbjct: 680 QQTSP--------KKDAAPKQDLSKAPEPKKP--PPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 685 FKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL-------SATQIKQEPAEEYET- 736
KP P P P+ P P P P SAT P+ + ++
Sbjct: 730 SKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
Query: 737 -PESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKK 795
E PP ++ S P P+ S +K + R SD + G K
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR-----PASDSKIISHPGPSSESK 841
Query: 796 RADLVEKVRREAEQRAREEK 815
V+ V+++ E + + K
Sbjct: 842 GQKQVDPVQKKEEPKKAQTK 861
Score = 85.1 bits (209), Expect = 4e-16
Identities = 186/811 (22%), Positives = 252/811 (31%), Gaps = 139/811 (17%)
Query: 11 SMRSGRKKEAPGP-REELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNK 69
+ + G +K PGP + + G P + + T A+ + P +
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 70 QGRSEEISESESEETNA--PKKTKTEQELPRPQSPSDLDSLDGRSL-NDDGSSDPRDIDQ 126
G + SE + A P KT + P P P + L G P
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435
Query: 127 DNRSTSPSIYSPGSV---ENDSDSSSGLSQGPARPYH--PPPLFPPSPQP-PDSTPRQPE 180
+ T PG + + +S GP +P P P PP QP P P Q
Sbjct: 436 PTK-TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP 494
Query: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGP-PMGPKGGG 239
S +P + P +P ++ PG+ P P PG P P P
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAKPSAQQ 553
Query: 240 AASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP---TTPVGGGNLPSAPPPANF-- 294
+ V GK PPT S + G P T P TT + L P ANF
Sbjct: 554 STKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL----LLHVPEKANFNT 609
Query: 295 -----------------PHVT-----------------------PNLPPPP-ALRPLNNA 313
PH+T P+ P P P+
Sbjct: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTT 669
Query: 314 SASPPGLGAQPLPGHL-PSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR 372
SA + P P P A + P P+K P L P S+ A PP
Sbjct: 670 SAVSK---SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP-- 724
Query: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
+ S S A S S P + P P P T L S+ T+P +
Sbjct: 725 ----EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT--TKPDI 778
Query: 433 PSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ-----STAHP------PVSTHHH 481
PS V SQ P L +A P P TG + S A P + +H
Sbjct: 779 PSSKVQSQAEEKTTP---PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
Query: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRP 541
+ + Q+Q Q++++ + P P A P P GS P
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP--KGS-----------------P 876
Query: 542 YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF 601
PPGP P V Q P P S S + S P S P+
Sbjct: 877 TPPGPR--PTAGQTVPTPQQSPK-PQEQSRRFSLNLGSITDAPKSQPT------------ 921
Query: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
P TVT I + AS+ TA PGP PGA P P
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNL--ISTAGQPGP----HSQSGPGAPMKQAP---APSQ 972
Query: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL 721
PP+ + PP G +PPA + T PA P P +
Sbjct: 973 PPT--SQGPPKSTGQAPPAPAKSIPVKKETKA-----PAAEKLEPKAEQAPTVKRTETEK 1025
Query: 722 SATQIKQEPAEEYETPESPVPPARSPSPPPK 752
IK + E ++ +P SP P+
Sbjct: 1026 KPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
Score = 76.3 bits (186), Expect = 2e-13
Identities = 136/590 (23%), Positives = 193/590 (32%), Gaps = 101/590 (17%)
Query: 235 PKGGGAASSVGGPNGGKQHPPPTT------------------PISVSSSGASGAPPTKPP 276
P+G AA++ GG G P T I+ S A G P
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK---- 68
Query: 277 TTPVGGGNLPSAPPPANFPHVTPNL----PPPPALRPLNNASASPPGLGA---------- 322
G++P A + H L PP + RP + + PGL
Sbjct: 69 ------GSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE 122
Query: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF-PYSSSSSS 381
Q LPG PS ++ + E ++ P S A S+ + +F P+ S S
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDS 182
Query: 382 SAAASSSSSSSSSSASPFPASQALPSYPHSFPPP------------------TSLSVSNQ 423
A+ ++ + + P PP T S+S+Q
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ 242
Query: 424 PPKYTQPSLPSQAVWSQGPPPPPP--YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481
P+ + P QGP P + +L +A P + A V
Sbjct: 243 QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR---PQTKQADIVRGESVKPSLP 299
Query: 482 HHQQQQQQQQQQQQQQQQQQQHHGNS-GPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
+ QQ + QQ H + GP P A P L P A P G+++
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL-------TKPLAQQP--GTVK 350
Query: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
P P PP + GP PP + + S+ Q P G A P
Sbjct: 351 PPVQPPGTTKPPAQPL-----GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 601 FPPVPTV----TTSSATLSTVIATVASSPAGYKT-ASPPGPPPYGKRAPSPG---AYKTA 652
P P T + + A +P KT PGP + PG A +T
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 653 T--PPGYKPG--SPPSFRTGT---PPGYRGTSPPAG--PGTFKPGSPTVGPGPLPPAGPS 703
PP PG PP + G PP G++ P PG+ KP P PGP P+ P
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP--PPQQPGPAKPS-PQ 522
Query: 704 GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKV 753
S PP P S P + +P+ + T + P PP V
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572
Score = 52.4 bits (124), Expect = 3e-06
Identities = 93/441 (21%), Positives = 144/441 (32%), Gaps = 58/441 (13%)
Query: 38 VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELP 97
VS+SS+ K + + ++ EE +TP + S + E +P +K +P
Sbjct: 767 VSSSSATTKPDIPSSKVQ-SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKA---IP 822
Query: 98 RPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPAR 157
RP S S + S G S G + +D + P + P
Sbjct: 823 RPASDSKIISHPGPSSESKGQ---KQVDPVQKKEEPK-------------KAQTKMSPKP 866
Query: 158 PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP 217
P P P+P P T Q PT +P SR F G+ P
Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQ----------TVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 218 QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT 277
+ P ++G G GA+ N +S++G G P
Sbjct: 917 KSQPTTPQETVTGKLFG---FGASIFSQASN------------LISTAGQPGPHSQSGPG 961
Query: 278 TPVGGGNLPSAPPPANFP-HVTPNLPPPPALR-PLNNASASPPGLGAQPLPGHLPSPHAM 335
P+ PS PP + P T PP PA P+ + +P +P P+
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395
P K T P LP +P P P + + + + ++ +
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 396 ASPFPASQA-LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454
+ PH L ++ Q TQ ++ Q + PP P +
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQ----TQRAISGQLGDIRKMPPAP------SG 1131
Query: 455 SNAHPGPFPPSTGAQSTAHPP 475
A P P P + +Q TA PP
Sbjct: 1132 PKASPMPVPTESSSQKTAVPP 1152
Score = 50.1 bits (118), Expect = 1e-05
Identities = 37/115 (32%), Positives = 48/115 (41%), Gaps = 18/115 (15%)
Query: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS 419
PP SS A PM+ S++ +S +S S P+ +LP+ P F +SL
Sbjct: 2343 PP--SSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
Query: 420 VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474
+S QPP P P PPPPPP P P PP T + T P
Sbjct: 2401 ISAQPPPPPPPPPPPPP-----PPPPPP-----------PPPLPPPTSPKPTILP 2439
Score = 45.1 bits (105), Expect = 4e-04
Identities = 87/426 (20%), Positives = 143/426 (33%), Gaps = 53/426 (12%)
Query: 46 KAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDL 105
KA+K V EA K + + S SE+ + P LP + S
Sbjct: 2303 KAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIA---LPMKEQLSTT 2359
Query: 106 DSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF 165
G + + + + S+ P+ P + D S+ P P PPP
Sbjct: 2360 YFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP 2419
Query: 166 PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP-------------------PTSRMF 206
PP P PP P P+ + P +T P P +R+
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRIC 2479
Query: 207 QAPPGAPPPHPQLYPGGT----GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT----- 257
P PP P P G S PP+ PK HP PT
Sbjct: 2480 TTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLT 2539
Query: 258 --TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASA 315
+++ +S P P +P + P +V LP P ++AS
Sbjct: 2540 SSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599
Query: 316 S----PPG------LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
+ P G + +P+ +P A+ +P E+ ++ + + +
Sbjct: 2600 AITSWPLGSPSKDLVSVEPVFSVVPPVTAV-----EIPISSEQTFYISGALQTFSATPVT 2654
Query: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP-PTSL-SVSNQ 423
AP+ P S + + S + S++ S +P S L S + PP P +L ++ +
Sbjct: 2655 APSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP---SVGLSSISITIPPEPLALDNIHLE 2711
Query: 424 PPKYTQ 429
P+Y +
Sbjct: 2712 KPQYKE 2717
Score = 38.9 bits (89), Expect = 0.029
Identities = 64/243 (26%), Positives = 82/243 (33%), Gaps = 32/243 (13%)
Query: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610
PP S ++ P +S++ +S T P S PS P + P P P +S
Sbjct: 2343 PPSSVIAL----PMKEQLSTTYFTSGETFGQEKPASQ-LPSGSPSVSSLPAKPRPFFRSS 2397
Query: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
S +S P PP PPP P P + K P K T TP
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPP---PLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 671 PGYRGTSPPAGPGTFKPGSP-----TVGPGPLPP---AGPSGL-----PSLPPPPAAPAS 717
T+ G P T P P+PP + PSGL P PP AP
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Query: 718 GPPLSATQIKQEPAEEYETPE----------SPVPPARSPSPPPKVVDVPSHASQSARFN 767
P T Q+P + + P + V A P P P S RF+
Sbjct: 2515 VIPQLPT-TTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFS 2573
Query: 768 KHL 770
K L
Sbjct: 2574 KSL 2576
Score = 35.4 bits (80), Expect = 0.33
Identities = 66/271 (24%), Positives = 82/271 (30%), Gaps = 60/271 (22%)
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
P+ S SL PP P PPP P PP S P
Sbjct: 2392 PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS------------------P 2433
Query: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK-----TASPPGPPPYGKRA 643
P+ P+ PV T T ++T+ T G T +PP PP
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
Query: 644 PSPGAYKTATPPGYKPGSP----PSFRTGT---------PPGYRGTSPP----AGPGTFK 686
PS + P P +P P T T P G TS +K
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYK 2553
Query: 687 PGSPTVGPGPLPPAGPSGLP-------------SLPPPPAAPASGPPLSATQ-IKQEPAE 732
SPT PL P P +LP P P SA+Q I P
Sbjct: 2554 LPSPT---SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDS---SASQAITSWPLG 2607
Query: 733 EYETPESPVPPARSPSPPPKVVDVPSHASQS 763
V P S PP V++P + Q+
Sbjct: 2608 SPSKDLVSVEPVFSVVPPVTAVEIPISSEQT 2638
Score = 35.0 bits (79), Expect = 0.42
Identities = 85/423 (20%), Positives = 140/423 (33%), Gaps = 54/423 (12%)
Query: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS-------------PFPASQALPS 407
P+ S+ PP P +SS SS + SSS ++ S F S+ + S
Sbjct: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISS 2228
Query: 408 ---YPHS---FPPPTSLSVSNQPPKYTQPS----------LPSQAVWSQGPPPPPPYGRL 451
+P S +P S+S+ P + S + S + S P P P
Sbjct: 2229 STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADT 2288
Query: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511
++ P + T + + ++ +++ + ++ + + PP
Sbjct: 2289 VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDH----PP 2344
Query: 512 PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
P++ S + + G +P + LP VS A P P SS
Sbjct: 2345 SSVIALPMKEQLS--TTYFTSGETFGQEKP----ASQLPSGSPSVSSLPAKPR-PFFRSS 2397
Query: 572 SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPP--VPTVTTSSATLSTVIATVASSPAGYK 629
S S+ P P P P P P PP P T TV + V ++ +
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD 2457
Query: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS 689
+ + P T P P P S P G T P +P
Sbjct: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI----PSGLVFTHRP------EPSK 2507
Query: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYE--TPESPVPPARSP 747
P + P P+ P P+ P S+ + + +Y+ +P SP+ P +
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNK 2567
Query: 748 SPP 750
S P
Sbjct: 2568 SSP 2570
Score = 34.7 bits (78), Expect = 0.55
Identities = 68/299 (22%), Positives = 108/299 (36%), Gaps = 53/299 (17%)
Query: 632 SPPGPPP--YGKRAP-SPG-AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP 687
SPP P Y +P SPG A ++A P KP PPA P T K
Sbjct: 3615 SPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKM 3674
Query: 688 GSPTVG-PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS 746
++ P PL P A +S P T+ + T +
Sbjct: 3675 MQRSMSDPKPLSPT------------ADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKR 3722
Query: 747 --PSPPPKVVDVPSHASQSARFNKHLDR--GFNSCARS--------DLYFVPLEGSKLAK 794
P+PPP+ + + ++ S R N+ AR+ +L V E +KL K
Sbjct: 3723 TLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRK 3782
Query: 795 KRADLVEKV----------------RREAEQRAREEKEREREREREKEREREKERELERS 838
K+A+L E+ R+EA + RE++ER + ++R+ + E+ +
Sbjct: 3783 KQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSST 3842
Query: 839 VKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSP 897
E + +E P P F +PP ++ + S Y + SP
Sbjct: 3843 RPTRIESQHGIERPRTAPQTEFSQF--------IPPQTQTESQLVPPTSPYTQYQYSSP 3893
Score = 33.5 bits (75), Expect = 1.2
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 23/136 (16%)
Query: 374 PYSSSSSSSAAASSSS-----------SSSSSSASPFPASQALP-SYPHSFPP----PTS 417
PYSS S S ++ SS SSSSS ++AL S+ H+ PTS
Sbjct: 4282 PYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTS 4341
Query: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
L +S ++ +P A S+ P P G+ + + A GP PP + T S
Sbjct: 4342 LPISQ-----SRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISA--DTRDQFGS 4394
Query: 478 THHHHHQQQQQQQQQQ 493
+H QQ +++ +
Sbjct: 4395 SHSLPEVQQHMREESR 4410
Score = 33.1 bits (74), Expect = 1.6
Identities = 25/102 (24%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 48 EKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDS 107
EK V+E P+ +G +S +E + K TKT +E P+P + D
Sbjct: 1274 EKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD--KTTKTIKEQPQPPCTAKPDQ 1331
Query: 108 LDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSS 149
++ + D D + SP S +D SSS
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSS 1373
Score = 33.1 bits (74), Expect = 1.6
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 19/121 (15%)
Query: 360 PPASSSAPAPPMRFPYSS---SSSSSAAASSSSSSSS---SSASPFPASQALPS--YPHS 411
PP P P + YSS + S+ A S S S SP +AL S P+
Sbjct: 3586 PPKDKKRPTP-LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYE 3644
Query: 412 FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST 471
P P +S P K P + ++ PP P +++ S + P P P+ S
Sbjct: 3645 KPLPDDIS----PQKVLHPDM------AKVPPASPKTAKMMQRSMSDPKPLSPTADESSR 3694
Query: 472 A 472
A
Sbjct: 3695 A 3695
Score = 32.3 bits (72), Expect = 2.8
Identities = 38/166 (22%), Positives = 59/166 (35%), Gaps = 19/166 (11%)
Query: 822 EREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPF-EPGSAVATVPPYLGPDT 880
+R+ R + K+ ++ R + +P + P P P +PP +PG + P P
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ 334
Query: 881 PALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARER 940
P S +P PG P P G P PA ++ E+
Sbjct: 335 P-----SGLTKPLAQQPGTVKPPVQPP---------GTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 941 DLRDRLKPGFEVKPSELEPLHG-VPGPGLDPFPRHG---GLALQPG 982
++ P +P + PGP P + G LA QPG
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 108 bits (269), Expect = 4e-23
Identities = 205/847 (24%), Positives = 271/847 (31%), Gaps = 157/847 (18%)
Query: 24 REELRSRGRASPGGVSTSSSDGKAEKSRQTAK--------KARVEEASTPKVNKQGRSEE 75
R E + GR SP +S S + + + + A + VNK +
Sbjct: 120 RSEQKLPGR-SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDL 178
Query: 76 ISESESEETNAPKKTKT---EQELP----------RPQSPSDLDSLDGRS-LNDDG---- 117
IS+SE+ + KK K EQ P +P P GR L DG
Sbjct: 179 ISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKS 238
Query: 118 --SSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYH--------------- 160
S P I T I P + L + +RP
Sbjct: 239 ISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL 298
Query: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPP--TSRMFQAPPGAPPPHPQ 218
P P PP QP TP +P A H P P +P T + Q P PP
Sbjct: 299 PSPSKPPIQQP---TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP--- 352
Query: 219 LYPGGTGGVLSGPPMGPKGGGA--ASSVGGPNGGKQHPPPTT---PISVSSSGASGAPPT 273
+ P GT + PP P G A G + P P P V + A P
Sbjct: 353 VQPPGT----TKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 274 KPPTTPVGGGNLPSAPPPANFPHV-TPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332
KPPT VG + P A P + +P P P P+ QP PG +P+
Sbjct: 409 KPPTQQVG-----TPKPLAQQPGLQSPAKAPGPTKTPVQ-----------QPGPGKIPAQ 452
Query: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSS 392
A GP K P+ P P PP PP + P S+ + S+
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP----GSAKPPSQQPGSTK 508
Query: 393 SSSASPFPASQALPSYPHSFPPPTSLSVSNQP-PKYTQPSLPSQAVWSQGPPPPPPYGRL 451
P PA + P P S PP+ S +P + P+ PS A S P G+
Sbjct: 509 PPPQQPGPAKPS-PQQPGSTKPPSQQPGSAKPSAQQPSPAKPS-AQQSTKPVSQTGSGKP 566
Query: 452 LANSNAHP-GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
L P PPS G T P +T ++ + Q P
Sbjct: 567 LQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPN 626
Query: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSS 570
PH E + G L P P P Q PV++
Sbjct: 627 -----PHLTEVKEWLCLNCQMKRALGGDLAPVPSSP-------------QPKLKTAPVTT 668
Query: 571 SS--NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY 628
+S + SS Q + P +P Q AP P P P V TL + A P
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV--KQPTLHGSPSAKAKQPPEA 726
Query: 629 KTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT------------------- 669
+ S P PP K P A KP P + T
Sbjct: 727 DSLSKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783
Query: 670 -PPGYRGTSPPAGPGTFKPGS--PTVGPGPLP--------PAGPSGLPSLPPPPAAPASG 718
T+PP + KP P G P PA S + S P P +
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQ 843
Query: 719 PPLSATQIKQEPAEEYETPESPVPPAR-----SPSPP----------PKVVDVPSHASQS 763
+ Q K+EP ++ +T SP P A+ SP+PP P P QS
Sbjct: 844 KQVDPVQKKEEP-KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQS 902
Query: 764 ARFNKHL 770
RF+ +L
Sbjct: 903 RRFSLNL 909
Score = 96.7 bits (239), Expect = 1e-19
Identities = 188/860 (21%), Positives = 285/860 (33%), Gaps = 144/860 (16%)
Query: 37 GVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQ----GRSEEISESESEETNAPKKTKT 92
G+ S A +S +K ++ + PK + + GR + S+S T+ ++
Sbjct: 65 GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDT---FRS 121
Query: 93 EQELPRPQSPSDLDSLDGRSLND-----DGSSDPRDIDQDNRSTSPSI----YSPGSVEN 143
EQ+LP +SPS + + +S D S P + + N ++ S ++P + +
Sbjct: 122 EQKLPG-RSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180
Query: 144 DSDSSS------------------GLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEP 185
DS++S G+ + P + P P+ P Q P P Q + + +
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPI--PKQQGPGRDPLQQDGTPKS 238
Query: 186 HPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG 245
S P + P T + Q P P P G +
Sbjct: 239 ISSQQPEKIKS-QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 246 GPNGGK---QHPPPTTPISVSSSGASGAP-PTKPPTTPVGGGNLPSAPPPANFPHVTPNL 301
P+ K Q P P P + P P KPP P G + P P V P
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357
Query: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361
P +PL A G++ P P A+ Q PPG K P P P P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQ-----PPGVGKTPAQQPGPAKPPT 412
Query: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVS 421
P P + P S + A + + PA QA P S
Sbjct: 413 QQVGTPKPLAQQP-GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG-----------KTS 460
Query: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481
Q T+P PSQ GP PPP PGP P +A PP
Sbjct: 461 AQQTGPTKP--PSQL---PGPAKPPPQ---------QPGPAKPPPQQPGSAKPP-----S 501
Query: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPP--------PPGAFPHPLEGGSSHHAHPYAMS 533
+ QQ + Q G++ PP P P P + + P + +
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQT 561
Query: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP-----VSSSSNSSSSTSQGSYPCS-- 586
S L+P P+ PP + + V +N ++ T + CS
Sbjct: 562 GSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 587 --HPSP-----------------SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAG 627
+P+P + G AP P P P + T A ++T A SSP
Sbjct: 622 GFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT--APVTTTSAVSKSSPQP 679
Query: 628 YKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT---PPGYRGTSPPAGPGT 684
+T+ K+ +P + P KP PP + T P + PP
Sbjct: 680 QQTSP--------KKDAAPKQDLSKAPEPKKP--PPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 685 FKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL-------SATQIKQEPAEEYET- 736
KP P P P+ P P P P SAT P+ + ++
Sbjct: 730 SKPAPP---KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQ 786
Query: 737 -PESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKK 795
E PP ++ S P P+ S +K + R SD + G K
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR-----PASDSKIISHPGPSSESK 841
Query: 796 RADLVEKVRREAEQRAREEK 815
V+ V+++ E + + K
Sbjct: 842 GQKQVDPVQKKEEPKKAQTK 861
Score = 85.1 bits (209), Expect = 4e-16
Identities = 186/811 (22%), Positives = 252/811 (31%), Gaps = 139/811 (17%)
Query: 11 SMRSGRKKEAPGP-REELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNK 69
+ + G +K PGP + + G P + + T A+ + P +
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 70 QGRSEEISESESEETNA--PKKTKTEQELPRPQSPSDLDSLDGRSL-NDDGSSDPRDIDQ 126
G + SE + A P KT + P P P + L G P
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435
Query: 127 DNRSTSPSIYSPGSV---ENDSDSSSGLSQGPARPYH--PPPLFPPSPQP-PDSTPRQPE 180
+ T PG + + +S GP +P P P PP QP P P Q
Sbjct: 436 PTK-TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP 494
Query: 181 ASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGP-PMGPKGGG 239
S +P + P +P ++ PG+ P P PG P P P
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGSAKPSAQQPSPAKPSAQQ 553
Query: 240 AASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP---TTPVGGGNLPSAPPPANF-- 294
+ V GK PPT S + G P T P TT + L P ANF
Sbjct: 554 STKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL----LLHVPEKANFNT 609
Query: 295 -----------------PHVT-----------------------PNLPPPP-ALRPLNNA 313
PH+T P+ P P P+
Sbjct: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTT 669
Query: 314 SASPPGLGAQPLPGHL-PSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR 372
SA + P P P A + P P+K P L P S+ A PP
Sbjct: 670 SAVSK---SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP-- 724
Query: 373 FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
+ S S A S S P + P P P T L S+ T+P +
Sbjct: 725 ----EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT--TKPDI 778
Query: 433 PSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ-----STAHP------PVSTHHH 481
PS V SQ P L +A P P TG + S A P + +H
Sbjct: 779 PSSKVQSQAEEKTTP---PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
Query: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRP 541
+ + Q+Q Q++++ + P P A P P GS P
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP--KGS-----------------P 876
Query: 542 YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF 601
PPGP P V Q P P S S + S P S P+
Sbjct: 877 TPPGPR--PTAGQTVPTPQQSPK-PQEQSRRFSLNLGSITDAPKSQPT------------ 921
Query: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
P TVT I + AS+ TA PGP PGA P P
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNL--ISTAGQPGP----HSQSGPGAPMKQAP---APSQ 972
Query: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPL 721
PP+ + PP G +PPA + T PA P P +
Sbjct: 973 PPT--SQGPPKSTGQAPPAPAKSIPVKKETKA-----PAAEKLEPKAEQAPTVKRTETEK 1025
Query: 722 SATQIKQEPAEEYETPESPVPPARSPSPPPK 752
IK + E ++ +P SP P+
Sbjct: 1026 KPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
Score = 76.3 bits (186), Expect = 2e-13
Identities = 136/590 (23%), Positives = 193/590 (32%), Gaps = 101/590 (17%)
Query: 235 PKGGGAASSVGGPNGGKQHPPPTT------------------PISVSSSGASGAPPTKPP 276
P+G AA++ GG G P T I+ S A G P
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK---- 68
Query: 277 TTPVGGGNLPSAPPPANFPHVTPNL----PPPPALRPLNNASASPPGLGA---------- 322
G++P A + H L PP + RP + + PGL
Sbjct: 69 ------GSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSE 122
Query: 323 QPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF-PYSSSSSS 381
Q LPG PS ++ + E ++ P S A S+ + +F P+ S S
Sbjct: 123 QKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDS 182
Query: 382 SAAASSSSSSSSSSASPFPASQALPSYPHSFPPP------------------TSLSVSNQ 423
A+ ++ + + P PP T S+S+Q
Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQ 242
Query: 424 PPKYTQPSLPSQAVWSQGPPPPPP--YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481
P+ + P QGP P + +L +A P + A V
Sbjct: 243 QPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR---PQTKQADIVRGESVKPSLP 299
Query: 482 HHQQQQQQQQQQQQQQQQQQQHHGNS-GPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
+ QQ + QQ H + GP P A P L P A P G+++
Sbjct: 300 SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL-------TKPLAQQP--GTVK 350
Query: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
P P PP + GP PP + + S+ Q P G A P
Sbjct: 351 PPVQPPGTTKPPAQPL-----GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 601 FPPVPTV----TTSSATLSTVIATVASSPAGYKT-ASPPGPPPYGKRAPSPG---AYKTA 652
P P T + + A +P KT PGP + PG A +T
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG 465
Query: 653 T--PPGYKPG--SPPSFRTGT---PPGYRGTSPPAG--PGTFKPGSPTVGPGPLPPAGPS 703
PP PG PP + G PP G++ P PG+ KP P PGP P+ P
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP--PPQQPGPAKPS-PQ 522
Query: 704 GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKV 753
S PP P S P + +P+ + T + P PP V
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTV 572
Score = 52.4 bits (124), Expect = 3e-06
Identities = 93/441 (21%), Positives = 144/441 (32%), Gaps = 58/441 (13%)
Query: 38 VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELP 97
VS+SS+ K + + ++ EE +TP + S + E +P +K +P
Sbjct: 767 VSSSSATTKPDIPSSKVQ-SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKA---IP 822
Query: 98 RPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPAR 157
RP S S + S G S G + +D + P + P
Sbjct: 823 RPASDSKIISHPGPSSESKGQ---KQVDPVQKKEEPK-------------KAQTKMSPKP 866
Query: 158 PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP 217
P P P+P P T Q PT +P SR F G+ P
Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQ----------TVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 218 QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT 277
+ P ++G G GA+ N +S++G G P
Sbjct: 917 KSQPTTPQETVTGKLFG---FGASIFSQASN------------LISTAGQPGPHSQSGPG 961
Query: 278 TPVGGGNLPSAPPPANFP-HVTPNLPPPPALR-PLNNASASPPGLGAQPLPGHLPSPHAM 335
P+ PS PP + P T PP PA P+ + +P +P P+
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSS 395
P K T P LP +P P P + + + + ++ +
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 396 ASPFPASQA-LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454
+ PH L ++ Q TQ ++ Q + PP P +
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQ----TQRAISGQLGDIRKMPPAP------SG 1131
Query: 455 SNAHPGPFPPSTGAQSTAHPP 475
A P P P + +Q TA PP
Sbjct: 1132 PKASPMPVPTESSSQKTAVPP 1152
Score = 50.1 bits (118), Expect = 1e-05
Identities = 37/115 (32%), Positives = 48/115 (41%), Gaps = 18/115 (15%)
Query: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS 419
PP SS A PM+ S++ +S +S S P+ +LP+ P F +SL
Sbjct: 2343 PP--SSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLD 2400
Query: 420 VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHP 474
+S QPP P P PPPPPP P P PP T + T P
Sbjct: 2401 ISAQPPPPPPPPPPPPP-----PPPPPP-----------PPPLPPPTSPKPTILP 2439
Score = 45.1 bits (105), Expect = 4e-04
Identities = 87/426 (20%), Positives = 143/426 (33%), Gaps = 53/426 (12%)
Query: 46 KAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDL 105
KA+K V EA K + + S SE+ + P LP + S
Sbjct: 2303 KAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIA---LPMKEQLSTT 2359
Query: 106 DSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF 165
G + + + + S+ P+ P + D S+ P P PPP
Sbjct: 2360 YFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP 2419
Query: 166 PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP-------------------PTSRMF 206
PP P PP P P+ + P +T P P +R+
Sbjct: 2420 PPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRIC 2479
Query: 207 QAPPGAPPPHPQLYPGGT----GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT----- 257
P PP P P G S PP+ PK HP PT
Sbjct: 2480 TTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLT 2539
Query: 258 --TPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASA 315
+++ +S P P +P + P +V LP P ++AS
Sbjct: 2540 SSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQ 2599
Query: 316 S----PPG------LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
+ P G + +P+ +P A+ +P E+ ++ + + +
Sbjct: 2600 AITSWPLGSPSKDLVSVEPVFSVVPPVTAV-----EIPISSEQTFYISGALQTFSATPVT 2654
Query: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP-PTSL-SVSNQ 423
AP+ P S + + S + S++ S +P S L S + PP P +L ++ +
Sbjct: 2655 APSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP---SVGLSSISITIPPEPLALDNIHLE 2711
Query: 424 PPKYTQ 429
P+Y +
Sbjct: 2712 KPQYKE 2717
Score = 38.9 bits (89), Expect = 0.029
Identities = 64/243 (26%), Positives = 82/243 (33%), Gaps = 32/243 (13%)
Query: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610
PP S ++ P +S++ +S T P S PS P + P P P +S
Sbjct: 2343 PPSSVIAL----PMKEQLSTTYFTSGETFGQEKPASQ-LPSGSPSVSSLPAKPRPFFRSS 2397
Query: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
S +S P PP PPP P P + K P K T TP
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPP---PLPPPTSPKPTILPKKKLTVASPVTTATP 2454
Query: 671 PGYRGTSPPAGPGTFKPGSP-----TVGPGPLPP---AGPSGL-----PSLPPPPAAPAS 717
T+ G P T P P+PP + PSGL P PP AP
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Query: 718 GPPLSATQIKQEPAEEYETPE----------SPVPPARSPSPPPKVVDVPSHASQSARFN 767
P T Q+P + + P + V A P P P S RF+
Sbjct: 2515 VIPQLPT-TTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFS 2573
Query: 768 KHL 770
K L
Sbjct: 2574 KSL 2576
Score = 35.4 bits (80), Expect = 0.33
Identities = 66/271 (24%), Positives = 82/271 (30%), Gaps = 60/271 (22%)
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
P+ S SL PP P PPP P PP S P
Sbjct: 2392 PFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTS------------------P 2433
Query: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK-----TASPPGPPPYGKRA 643
P+ P+ PV T T ++T+ T G T +PP PP
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
Query: 644 PSPGAYKTATPPGYKPGSP----PSFRTGT---------PPGYRGTSPP----AGPGTFK 686
PS + P P +P P T T P G TS +K
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYK 2553
Query: 687 PGSPTVGPGPLPPAGPSGLP-------------SLPPPPAAPASGPPLSATQ-IKQEPAE 732
SPT PL P P +LP P P SA+Q I P
Sbjct: 2554 LPSPT---SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDS---SASQAITSWPLG 2607
Query: 733 EYETPESPVPPARSPSPPPKVVDVPSHASQS 763
V P S PP V++P + Q+
Sbjct: 2608 SPSKDLVSVEPVFSVVPPVTAVEIPISSEQT 2638
Score = 35.0 bits (79), Expect = 0.42
Identities = 85/423 (20%), Positives = 140/423 (33%), Gaps = 54/423 (12%)
Query: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS-------------PFPASQALPS 407
P+ S+ PP P +SS SS + SSS ++ S F S+ + S
Sbjct: 2169 PSESATSVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFEDSEEISS 2228
Query: 408 ---YPHS---FPPPTSLSVSNQPPKYTQPS----------LPSQAVWSQGPPPPPPYGRL 451
+P S +P S+S+ P + S + S + S P P P
Sbjct: 2229 STYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPEGPVADT 2288
Query: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP 511
++ P + T + + ++ +++ + ++ + + PP
Sbjct: 2289 VSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDH----PP 2344
Query: 512 PGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571
P++ S + + G +P + LP VS A P P SS
Sbjct: 2345 SSVIALPMKEQLS--TTYFTSGETFGQEKP----ASQLPSGSPSVSSLPAKPR-PFFRSS 2397
Query: 572 SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPP--VPTVTTSSATLSTVIATVASSPAGYK 629
S S+ P P P P P P PP P T TV + V ++ +
Sbjct: 2398 SLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFD 2457
Query: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS 689
+ + P T P P P S P G T P +P
Sbjct: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI----PSGLVFTHRP------EPSK 2507
Query: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYE--TPESPVPPARSP 747
P + P P+ P P+ P S+ + + +Y+ +P SP+ P +
Sbjct: 2508 PPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNK 2567
Query: 748 SPP 750
S P
Sbjct: 2568 SSP 2570
Score = 34.7 bits (78), Expect = 0.55
Identities = 68/299 (22%), Positives = 108/299 (36%), Gaps = 53/299 (17%)
Query: 632 SPPGPPP--YGKRAP-SPG-AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKP 687
SPP P Y +P SPG A ++A P KP PPA P T K
Sbjct: 3615 SPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKM 3674
Query: 688 GSPTVG-PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS 746
++ P PL P A +S P T+ + T +
Sbjct: 3675 MQRSMSDPKPLSPT------------ADESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKR 3722
Query: 747 --PSPPPKVVDVPSHASQSARFNKHLDR--GFNSCARS--------DLYFVPLEGSKLAK 794
P+PPP+ + + ++ S R N+ AR+ +L V E +KL K
Sbjct: 3723 TLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMARAKILQDIDRELDLVERESAKLRK 3782
Query: 795 KRADLVEKV----------------RREAEQRAREEKEREREREREKEREREKERELERS 838
K+A+L E+ R+EA + RE++ER + ++R+ + E+ +
Sbjct: 3783 KQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYLQGVAEDRDYMSDSEVSST 3842
Query: 839 VKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSP 897
E + +E P P F +PP ++ + S Y + SP
Sbjct: 3843 RPTRIESQHGIERPRTAPQTEFSQF--------IPPQTQTESQLVPPTSPYTQYQYSSP 3893
Score = 33.5 bits (75), Expect = 1.2
Identities = 38/136 (27%), Positives = 58/136 (42%), Gaps = 23/136 (16%)
Query: 374 PYSSSSSSSAAASSSS-----------SSSSSSASPFPASQALP-SYPHSFPP----PTS 417
PYSS S S ++ SS SSSSS ++AL S+ H+ PTS
Sbjct: 4282 PYSSGSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTS 4341
Query: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
L +S ++ +P A S+ P P G+ + + A GP PP + T S
Sbjct: 4342 LPISQ-----SRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISA--DTRDQFGS 4394
Query: 478 THHHHHQQQQQQQQQQ 493
+H QQ +++ +
Sbjct: 4395 SHSLPEVQQHMREESR 4410
Score = 33.1 bits (74), Expect = 1.6
Identities = 25/102 (24%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 48 EKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDS 107
EK V+E P+ +G +S +E + K TKT +E P+P + D
Sbjct: 1274 EKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD--KTTKTIKEQPQPPCTAKPDQ 1331
Query: 108 LDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSS 149
++ + D D + SP S +D SSS
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSS 1373
Score = 33.1 bits (74), Expect = 1.6
Identities = 33/121 (27%), Positives = 47/121 (38%), Gaps = 19/121 (15%)
Query: 360 PPASSSAPAPPMRFPYSS---SSSSSAAASSSSSSSS---SSASPFPASQALPS--YPHS 411
PP P P + YSS + S+ A S S S SP +AL S P+
Sbjct: 3586 PPKDKKRPTP-LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYE 3644
Query: 412 FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST 471
P P +S P K P + ++ PP P +++ S + P P P+ S
Sbjct: 3645 KPLPDDIS----PQKVLHPDM------AKVPPASPKTAKMMQRSMSDPKPLSPTADESSR 3694
Query: 472 A 472
A
Sbjct: 3695 A 3695
Score = 32.3 bits (72), Expect = 2.8
Identities = 38/166 (22%), Positives = 59/166 (35%), Gaps = 19/166 (11%)
Query: 822 EREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPF-EPGSAVATVPPYLGPDT 880
+R+ R + K+ ++ R + +P + P P P +PP +PG + P P
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ 334
Query: 881 PALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAAREREREARER 940
P S +P PG P P G P PA ++ E+
Sbjct: 335 P-----SGLTKPLAQQPGTVKPPVQPP---------GTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 941 DLRDRLKPGFEVKPSELEPLHG-VPGPGLDPFPRHG---GLALQPG 982
++ P +P + PGP P + G LA QPG
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
sapiens]
Length = 2231
Score = 107 bits (268), Expect = 5e-23
Identities = 167/687 (24%), Positives = 228/687 (33%), Gaps = 128/687 (18%)
Query: 152 SQGPARP-YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210
S G + P Y P PP P P S A+ + G M + A
Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433
Query: 211 GAPP-PHPQLYPGGTG---GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
A HP + PG G G G PM P G + P ++P S G
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493
Query: 267 ASGAPPTKPPTTPVG-GGNLPSAPPPANFPHVTPNLPPPPALRPLNN--ASASPPGLGAQ 323
G P P+G G P A +P +PP + ++ P Q
Sbjct: 494 PPG-----PQRYPIGIQGRTPGAMAGMQYPQ--QQMPPQYGQQGVSGYCQQGQQPYYSQQ 546
Query: 324 PLPGHLPSPHAM------------GQGMGGLPPGPEKGPTLAPS--------------PH 357
P P HLP P A Q M G P LAP P
Sbjct: 547 PQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 605
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
SLP S S P + SS+ SA+ S+SS S+ + P S PH+ P +S
Sbjct: 606 SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS------PHASPHLSS 659
Query: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST--GAQSTAHPP 475
+ G P P P G + ++ + GP P++ G+Q PP
Sbjct: 660 IP---------------------GGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 698
Query: 476 ----VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--PGAFPHPLEGGSSHHA-H 528
S+ H Q Q++ Q+ GP P PHP GG H
Sbjct: 699 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 758
Query: 529 PYAMSPSLGSLRPY-----PPGPAHLPPPHSQV-SYSQAGPNGPPVSSSSNSSSSTSQGS 582
+ S S G+ P P G PP +S V S S +GP GP + S+N+ S
Sbjct: 759 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP-GPGMGISANNQMHGQGPS 817
Query: 583 YPC-------------------------SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV 617
PC + SP QG P PP+PTV + +
Sbjct: 818 QPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAA 877
Query: 618 IATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
+ A++ A + S PG G A S P S P + + +
Sbjct: 878 VMQAAANSAQSRQGSFPGMNQSGLMASS------------SPYSQPMNNSSSLMNTQAPP 925
Query: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
P + +VG + G S LP LP G P Q + + + Y +
Sbjct: 926 YSMAPAMVNSSAASVGLADMMSPGESKLP-LPLKADGKEEGTP----QPESKSKDSYSSQ 980
Query: 738 ESPVPPARSPSPPPKVVDVPSHASQSA 764
PP P P + PS AS S+
Sbjct: 981 GISQPPTPGNLPVPSPMS-PSSASISS 1006
Score = 81.6 bits (200), Expect = 4e-15
Identities = 156/668 (23%), Positives = 200/668 (29%), Gaps = 112/668 (16%)
Query: 146 DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR--QPEASFEPHPSVTPTGYHAPMEPPTS 203
DS++G G A P PP L P + D+ P+ +P HP + G P
Sbjct: 106 DSAAG---GQADPPGPPLLSKPGDED-DAPPKMGEPAGGRYEHPGLGALGTQQP------ 155
Query: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG---------GKQHP 254
P PGG GG + P G AA + GGP G G Q
Sbjct: 156 -------------PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202
Query: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA-------- 306
P + +S+ A+GAP + P N P + H P P A
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQ-----NSHEGYPNSQCNHY-PGYSRPGAGGGGGGGG 256
Query: 307 --------LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
A A G GA + A G G GG G G + SP
Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGY-GGSSAGYGVLSSPRQ 315
Query: 359 LPPASSSAPAPPMRFPYSSSSSSSAAAS----SSSSSSSSSASPFPASQALPSYPHSFPP 414
P S +++ SAA + + S A+P +Q L S P
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATP-TLNQLLTS-----PS 369
Query: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-------FPPSTG 467
P S P+Y+ PS P PPP P + A A G G
Sbjct: 370 PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
Query: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEG-GSSH 525
AQ A P QQ+ P P P L G GS+
Sbjct: 423 AQYAAASPAWA-----AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
Query: 526 HAHPYAMSPSLGSLRPYPPGPAHLP------PPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
H+ P SP G PPGP P P + PP S
Sbjct: 478 HSQPQQSSPYPGGSYG-PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQ 536
Query: 580 QGSYP--CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
QG P P P P A Y S + S GY T S P
Sbjct: 537 QGQQPYYSQQPQPPHLPPQAQY---------LPSQSQQRYQPQQDMSQEGYGTRSQPPLA 587
Query: 638 PYGKRAPSPGAYKTATPPGYK--PGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG 695
P + P GS TGT +G + +
Sbjct: 588 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 647
Query: 696 PLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755
P P L S+P P+ G P+ + Q + P P S +P P PP +
Sbjct: 648 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP----PQPPGSQSE 703
Query: 756 VPSHASQS 763
SH + S
Sbjct: 704 SSSHPALS 711
Score = 80.9 bits (198), Expect = 7e-15
Identities = 144/602 (23%), Positives = 196/602 (32%), Gaps = 97/602 (16%)
Query: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPV- 280
GG GG G G GGG + GG G + + G G V
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310
Query: 281 -----GGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHLPSPHA 334
GG + P ++ A A + GA P L L SP
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
Query: 335 MGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAP---------------APPMRFPYSSSS 379
M + GG P P+ P P S P + ++A M Y+++S
Sbjct: 371 MMRSYGGSYP-EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAAS 429
Query: 380 SSSAAASSSSSSSSSSASPFPA---SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQA 436
+ AAA S + S +P P SQ P P P + + P Q S P
Sbjct: 430 PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489
Query: 437 VWSQGPPPPPPY-----GR---LLANSNAHPGPFPPSTGAQSTA---------------H 473
S GPP P Y GR +A PP G Q +
Sbjct: 490 -GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQ 548
Query: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
PP + Q QQ+ Q QQ Q+ + S PP P+ + P ++
Sbjct: 549 PPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608
Query: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPSQ 592
GS+ P G ++ + S A S+S S+SS S P P SP
Sbjct: 609 DLSGSIDDLPTG--------TEATLSSA-------VSASGSTSSQGDQSNPAQSPFSPHA 653
Query: 593 GPQ-----GAPYPFP---PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
P G P P P PV + + S +S AS P PPG P
Sbjct: 654 SPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP-----ASIPGSQMPPQPPGSQSESSSHP 708
Query: 645 SPGAYKTATPPGYKPG---SPPSFRTGTPPGYRGTSPPAGPG--------TFKPGSPTVG 693
+ G+ G +P + G SP PG +F+ + +
Sbjct: 709 ALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGT 768
Query: 694 PGP-LPPAGPSGLPSLPPP----PAAPAS--GPPLSATQIKQEPAEEYETPESPVPPARS 746
GP + GP G S PP P+A S GP + + Q + P VP R
Sbjct: 769 YGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRM 828
Query: 747 PS 748
PS
Sbjct: 829 PS 830
Score = 77.0 bits (188), Expect = 1e-13
Identities = 188/849 (22%), Positives = 278/849 (32%), Gaps = 186/849 (21%)
Query: 6 NKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTP 65
N SM+ S + GP G P V+ + + A + A A+ + S P
Sbjct: 841 NMSSMTPSSPGMSQQGGP-----GMGPPMPT-VNRKAQEAAAAVMQAAANSAQSRQGSFP 894
Query: 66 KVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGR-----SLNDDGSSD 120
+N+ G S S+ N Q P +P+ ++S ++ S
Sbjct: 895 GMNQSGLMAS-SSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKL 953
Query: 121 PRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDS------ 174
P + D + P S DS SS G+SQ P P L PSP P S
Sbjct: 954 PLPLKADGKEEGTP--QPESKSKDSYSSQGISQPPT----PGNLPVPSPMSPSSASISSF 1007
Query: 175 ---------------TPRQPEASFEPHPSVTPTG------YHAPMEPPTSRM------FQ 207
TP P++S S T TG Y EP F
Sbjct: 1008 HGDESDSISSPGWPKTPSSPKSS-----SSTTTGEKITKVYELGNEPERKLWVDRYLTFM 1062
Query: 208 APPGAPPPHPQLYPGGTGGVLSGPPMGPKGGG------AASSVGG---PNGGKQHPPPTT 258
G+P V S P +G K +GG N K+ T
Sbjct: 1063 EERGSP-------------VSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELAT 1109
Query: 259 PISVSSSGASGAPPTKPPTTPVGGGNLP----SAPPPANFPHVTPNLPPPPALRPLNNAS 314
++V +S ++ + K + PPP F T + P L+P
Sbjct: 1110 NLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFS--TGDTKKQPKLQP----- 1162
Query: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS--LPPASSSAPAPPMR 372
SP G+ P +P + G PG K PT A +PH P + +
Sbjct: 1163 PSPANSGSLQGP---QTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVH 1219
Query: 373 FPYSSSSSSSAAASSSSSSSSS------------------SASPFPASQALPSYPHSFPP 414
P+S S SS +S + ++ + PF + +P F
Sbjct: 1220 DPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMT 1279
Query: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-----RLLANSNAHPGPFPPST--- 466
+ S+ Y Q + + G PYG R +PG PPS
Sbjct: 1280 QGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPP 1339
Query: 467 --GAQSTAHPPVSTHHHH-----------HQQQQQQQQQQQQQQQQQQQHHGN-SGP--- 509
G Q +P + H H+ Q QQQ+ Q+ G+ SGP
Sbjct: 1340 YGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRR 1399
Query: 510 PPPGAFPHP-----LEGGSSHHAH---------PYAMSPSLGSLRPYPPGPAHLPPPHSQ 555
P G +P+P ++G H P S S G + +P P+
Sbjct: 1400 PIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQ- 1458
Query: 556 VSYSQAGPNGP---PVSSSSNSSSSTSQGSYPCSHPS--PSQGPQGAPYPFPPVPTVTTS 610
++ GP GP P N + +H S PS Q PY +S
Sbjct: 1459 ---NRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPY--------MSS 1507
Query: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
SA++ + + P +PP P + RAPSP +++ + P P +
Sbjct: 1508 SASMQPI-----TRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKM 1562
Query: 671 PGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP 730
T P S GP P PP P PP + AS P L Q ++
Sbjct: 1563 QKVMPTVPT---------SQVTGPPPQPP--PIRREITFPPGSVEASQPVLK--QRRKIT 1609
Query: 731 AEEYETPES 739
+++ TPE+
Sbjct: 1610 SKDIVTPEA 1618
Score = 64.7 bits (156), Expect = 5e-10
Identities = 74/277 (26%), Positives = 94/277 (33%), Gaps = 60/277 (21%)
Query: 460 GPFPPSTGAQSTAHPPVSTHHHHHQ----------------QQQQQQQQQQQQQQQQQQH 503
G P + Q H + HHHHH QQQQQQQQQQQQQQQQQQH
Sbjct: 15 GEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQH 74
Query: 504 HGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGP 563
++ GA GG + P P G + G QA P
Sbjct: 75 PISNNNSLGGA------GGGAPQPGPDMEQPQHGGAKDSAAG-------------GQADP 115
Query: 564 NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV-----I 618
GPP+ S P P G Y P + + T ++
Sbjct: 116 PGPPLLSKPGDEDDA---------PPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166
Query: 619 ATVASSPAGYKTASPPGPPPYGKRAP---------SPGAYKTATPPGYKPGSPPSF--RT 667
A V Y +A+P P G+ P SPG + G+P S
Sbjct: 167 AAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQ 226
Query: 668 GTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
+ GY + PG +PG+ G G G SG
Sbjct: 227 NSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263
Score = 52.0 bits (123), Expect = 3e-06
Identities = 160/726 (22%), Positives = 241/726 (33%), Gaps = 150/726 (20%)
Query: 77 SESESEETN------APKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130
+ S+ +++N +P + +P SPS + S G + + G P I
Sbjct: 635 TSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP 694
Query: 131 TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPP--SPQPPDSTPRQPEASFEPHPS 188
P PGS +++S S LSQ P P + +PQ P+Q S PHPS
Sbjct: 695 PQP----PGS-QSESSSHPALSQSPM-PQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPS 748
Query: 189 V---TPTGYHAPMEPPTS-----RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP----- 235
G + + +S +M Q P P Y G SGP G
Sbjct: 749 PGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISAN 808
Query: 236 ---KGGGAASSVGG------PNGGKQHPP---PTTPISVSSSGAS--GAPPTKPPTTPVG 281
G G + G P+ G Q+ P + ++ SS G S G P PP V
Sbjct: 809 NQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVN 868
Query: 282 ----------------------------------GGNLPSAPPPANFPHVTPNLPPPPAL 307
+ P + P N + PP ++
Sbjct: 869 RKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSM 928
Query: 308 RP-LNNASASPPGLGAQPLPGH--LPSP-HAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS 363
P + N+SA+ GL PG LP P A G+ G P + + + S PP
Sbjct: 929 APAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTP 988
Query: 364 SSAPAPPMRFPYSSSSSSSAAASSSS----------SSSSSSASPFPASQALPSYPHSFP 413
+ P P P S+S SS S S SS SS+S + Y
Sbjct: 989 GNLPVPSPMSPSSASISSFHGDESDSISSPGWPKTPSSPKSSSSTTTGEKITKVYELGNE 1048
Query: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY----------GRLLANSNAHPGPFP 463
P L V + P ++ + G P + G N N
Sbjct: 1049 PERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELA 1108
Query: 464 P--STGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521
+ G S+A + + + + + ++ ++ + G++ P P P
Sbjct: 1109 TNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANS 1168
Query: 522 GS------SHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG-----PPVSS 570
GS +M+ G L+ PP PA PH Q++ Q G + P S
Sbjct: 1169 GSLQGPQTPQSTGSNSMAEVPGDLK--PPTPA--STPHGQMTPMQGGRSSTISVHDPFSD 1224
Query: 571 SSNSS-----SSTSQGSYP--CSHP--------SPSQGPQGA--PYPFPPVPTVTTSSAT 613
S+SS S T Y S P P++ P G P P +T
Sbjct: 1225 VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMP 1284
Query: 614 LSTVIATVASSPAG--------------YKTASPPGPPPYGKRAPSPGAYKTATPP--GY 657
S++ SP+G Y + PYG++ P G + PP G+
Sbjct: 1285 NSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGP-PSGQPPYGGH 1343
Query: 658 KPGSPP 663
+PG P
Sbjct: 1344 QPGLYP 1349
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 102 bits (254), Expect = 2e-21
Identities = 179/729 (24%), Positives = 232/729 (31%), Gaps = 109/729 (14%)
Query: 97 PRPQSPSDLDSLDGRSLNDDG-SSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP 155
P PQ P+ L G SS P Q SP + SP S S Q
Sbjct: 758 PAPQIPA------AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSR-PQSV 810
Query: 156 ARPYHPPPLFP-PSPQPPDSTPR----QPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210
+RP PPL P P PQ P + P Q + P S P +PP Q P
Sbjct: 811 SRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPE 870
Query: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA 270
G PP P L P T +S+V + P TP
Sbjct: 871 GPLPPAPHLPPSST----------------SSAVASSSETSSRLPAPTPSDFQLQFPPSQ 914
Query: 271 PPTKPPTTP-----VGGGNLPSAPPPANFPHVT---PNLPPPPALRP-----------LN 311
P K PT P V P PPP F VT P LP P AL N
Sbjct: 915 GPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQN 974
Query: 312 NASASPPGLGAQPLPGHLPSPHA----MGQGMGGLPPGPEKGPTLAP-SPHSLPP----- 361
A +P G L SP A GQ G P P P AP + LPP
Sbjct: 975 KAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAE 1034
Query: 362 ---------------ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS----SASPFPAS 402
A+SS P P Y S S + S + S
Sbjct: 1035 NKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGS 1094
Query: 403 QALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-RLLANSNAHPGP 461
P Y +FP P Q +LPS + + + +LL + A
Sbjct: 1095 VLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNK 1154
Query: 462 FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521
+ +S P + + Q+++ +Q + + + P+
Sbjct: 1155 YRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAA 1214
Query: 522 GSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH--SQVSYSQAGPNGPPVSSSSNSSSSTS 579
S H P G L PG + PPPH +++ G G P + + +SSS S
Sbjct: 1215 SSEGH-----RLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLS 1269
Query: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGY-KTASPPGPPP 638
S S S + P P P + T A + AG K P
Sbjct: 1270 SSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDP 1329
Query: 639 YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGP-----GTFKPGSPTV- 692
+ P P K A PP P PP TG G PPA P GT P P +
Sbjct: 1330 VHQPPPPPATLKVAEPPPRPPPPPPP--TGQMNGTVDHPPPAAPERKPLGT-APHCPRLP 1386
Query: 693 ----------GPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVP 742
GPG P P+G P PA ++ I++ A E E + +
Sbjct: 1387 LRKTYRENVGGPG-APEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRML- 1444
Query: 743 PARSPSPPP 751
+ P P P
Sbjct: 1445 --KGPPPEP 1451
Score = 100 bits (250), Expect = 6e-21
Identities = 151/572 (26%), Positives = 190/572 (33%), Gaps = 134/572 (23%)
Query: 196 APMEPPTSRMFQAP----PGAPPPHPQLYPGGTGG--VLSGPPMGPKGGGAASSVGGPNG 249
AP++ +FQ P G+ P Q P G VL G + P A + + P+G
Sbjct: 545 APIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS---AVAMLNTPDG 601
Query: 250 GKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309
Q P TP + + A P P P+ P P PP P
Sbjct: 602 LVQ---PATPAAATGEAAPVLTVQPAPQAP------PAVSTPLPLGLQQPQAQQPPQA-P 651
Query: 310 LNNASASPPGLGAQPLPGHLPSPH--AMGQGMGG--------------LPPGPEKGPTLA 353
A+A P QP PG SP +GQ LP + P A
Sbjct: 652 TPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSA 711
Query: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
PH PAS APP + ++ + A + S ASP PA Q + P P
Sbjct: 712 EGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP 771
Query: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAH 473
P+S PSLP QA P P P+ P PPS QS +
Sbjct: 772 GPSS-----------SPSLPHQAPLGDSPHLPSPH-------PTRPPSRPPSR-PQSVSR 812
Query: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
PP H Q Q Q G PPP + P P G
Sbjct: 813 PPSEPPLHPCPPPQAPPTLPGIFVIQNQ-----LGVPPPASNPAPTAPGPPQPPLRPQSQ 867
Query: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS---- 589
P G P PP P HLPP +SS+ +SSS + P PS
Sbjct: 868 PPEG---PLPPAP-HLPPSS---------------TSSAVASSSETSSRLPAPTPSDFQL 908
Query: 590 ---PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSP 646
PSQGP +P P P + V P PPP P P
Sbjct: 909 QFPPSQGPHKSPTPPPTLHLV-----------------------PEPAAPPP-----PPP 940
Query: 647 GAYKTATPPGYKPGSPPSFRT---GTPPGY----RGTSPPAGPGTFKPGSPTVGPGPLPP 699
++ T P P + P G + PA P T S ++GP P
Sbjct: 941 RTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQT----STSLGPLTSPA 996
Query: 700 A-------GPSGLPSLPPPPAAPASGPPLSAT 724
A PSG P+ P APA P++AT
Sbjct: 997 ASVLVSGQAPSGTPTAPSHAPAPA---PMAAT 1025
Score = 87.4 bits (215), Expect = 7e-17
Identities = 165/684 (24%), Positives = 233/684 (34%), Gaps = 150/684 (21%)
Query: 163 PLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPG 222
P PS QP P + P P+V P++P P G PP +LY
Sbjct: 316 PTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPK-------PAGVLPP--KLYQ- 365
Query: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASG---------APPT 273
L+ P P G + G P Q P ++ ++G +G AP
Sbjct: 366 -----LTPKPFAP-AGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPAL 419
Query: 274 K------PPTTPVGGGNLPSAPPPA------------------NFPHVTPN-----LPPP 304
+ PP T G P PP A H+ P LP
Sbjct: 420 QANVFKQPPATTTGAA--PPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGA 477
Query: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG-------LPPGPEKGPTLAPSPH 357
PA++ SA P +G Q L +PH GQ + L GP LAP H
Sbjct: 478 PAVQLPQQLSALPANVGGQILAA--AAPHTGGQLIANPILTNQNLAGPLSLGPVLAP--H 533
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP-PPT 416
S ++ A P++ + S ++ S + + P PA A + PP+
Sbjct: 534 SGAHSAHILSAAPIQV--GQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPS 591
Query: 417 SLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476
++++ N P QP+ P+ A P P P P P V
Sbjct: 592 AVAMLNTPDGLVQPATPAAATGEAAPV-----------LTVQPAPQAP---------PAV 631
Query: 477 STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHH-----AHPYA 531
ST QQ Q QQ Q Q + PP P P G +S P +
Sbjct: 632 STPLPLGLQQPQAQQPPQAPTPQ-------AAAPPQATTPQPSPGLASSPEKIVLGQPPS 684
Query: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS 591
+P+ ++ LP SQ S GP+ +S S+ +Q P + +
Sbjct: 685 ATPT--AILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKG 742
Query: 592 QG-------PQGAPYPFPPVPTVT-------TSSATL--STVIATVASSPAGYKT---AS 632
G Q +P P P +P +SS +L + P+ + T +
Sbjct: 743 AGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSR 802
Query: 633 PPGPPPYGKRAPSPGAYKTATPPGYKP------------GSPPSFRTGTPPGYRGTSPPA 680
PP P R PS PP P G PP P PP
Sbjct: 803 PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPL 862
Query: 681 GPGTFKPGSPTVGPGPLPPAGPSGLPSLPP--PPAAPASGPPLSATQIKQEPAE-EYETP 737
P + P GPLPPA P LPP +A AS S+ P++ + + P
Sbjct: 863 RPQSQPP------EGPLPPA-----PHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFP 911
Query: 738 ESPVPPARSPSPPPKVVDVPSHAS 761
S P +SP+PPP + VP A+
Sbjct: 912 PSQ-GPHKSPTPPPTLHLVPEPAA 934
Score = 75.5 bits (184), Expect = 3e-13
Identities = 98/344 (28%), Positives = 123/344 (35%), Gaps = 78/344 (22%)
Query: 153 QGPARPYHPPPLFPPSPQ--------------PPDSTPRQPEASFEPH---------PSV 189
Q P P PL PQ PP +T QP PS
Sbjct: 626 QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA 685
Query: 190 TPTGYHAPMEPPTSRMF------QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASS 243
TPT A + + +MF Q P A PH + P ++S PP A
Sbjct: 686 TPT---AILTQDSLQMFLPQERSQQPLSAEGPHLSV-PASV--IVSAPPPAQDPAPATPV 739
Query: 244 VGGPNGGKQHPPPTTPISVSSSGASGAP-PTKPPTTPVGGGNLPSAPPPANFPHV----- 297
G G Q P S AS AP P P P+ G S+P + PH
Sbjct: 740 AKGAGLGPQAP---------DSQASPAPAPQIPAAAPLKGPGPSSSP---SLPHQAPLGD 787
Query: 298 TPNLPPPPALRPLNNASASPPGLGAQP------------LPGHLPSPHAMGQGMGGLPPG 345
+P+LP P RP + + P + P P LP + +G PP
Sbjct: 788 SPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA 847
Query: 346 PEKGPTLAPSPHSLP--PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQ 403
PT AP P P P S P P+ SS+S+A +SSS +SS +P P+
Sbjct: 848 SNPAPT-APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906
Query: 404 ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
L FPP S PP T +P A PPPPPP
Sbjct: 907 QL-----QFPPSQGPHKSPTPPP-TLHLVPEPA----APPPPPP 940
Score = 71.2 bits (173), Expect = 5e-12
Identities = 148/604 (24%), Positives = 202/604 (33%), Gaps = 119/604 (19%)
Query: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPN-LPP------PPALRPLNNASA 315
++S +G P +P G G+ P P P H TP + P PP L L
Sbjct: 312 AASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPF 371
Query: 316 SPPG--LGAQPLPGHLPSPHAMGQGMGGLPPGPE---------KGPTLAPSPHSLPPASS 364
+P G L Q PG LP Q + + G P L + PPA++
Sbjct: 372 APAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATT 431
Query: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP-------PTS 417
+ APP P + S S + SS PA LP P P
Sbjct: 432 TGAAPPQP-PGALSKPMSVHLLNQGSS-----IVIPAQHMLPGQNQFLLPGAPAVQLPQQ 485
Query: 418 LS-----VSNQPPKYTQPSLPSQAV-----WSQGPPPPPPYGRLLA-NSNAHPGPF---- 462
LS V Q P Q + +Q P G +LA +S AH
Sbjct: 486 LSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAA 545
Query: 463 PPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAF---PHPL 519
P G + PVS Q Q Q G + PP A P L
Sbjct: 546 PIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQ---GVTLPPSAVAMLNTPDGL 602
Query: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPP---HSQVSYSQAGPNGPPVSSSSNSSS 576
++ A +P L +++P P P + P Q +Q P P +++ +
Sbjct: 603 VQPATPAAATGEAAPVL-TVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQA 661
Query: 577 STSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSAT------------------LSTVI 618
+T Q S P SP + G P P +T S LS
Sbjct: 662 TTPQPS-PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPA 720
Query: 619 ATVASSPAGYKTASPPGP----------PPYGKRAPSPGAYKTATPP--GYKPGSPPSFR 666
+ + S+P + +P P P + +P+P A P G P S PS
Sbjct: 721 SVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLP 780
Query: 667 TGTP-------PGYRGTSPPAGPG------TFKPGSPTVGPGPLPPAGPSGLPSL----- 708
P P T PP+ P + P P + P P PP P LP +
Sbjct: 781 HQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCP-PPQAPPTLPGIFVIQN 839
Query: 709 ----PPP---PAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761
PPP PA A GPP + + +P PE P+PPA P V S +
Sbjct: 840 QLGVPPPASNPAPTAPGPPQPPLRPQSQP------PEGPLPPAPHLPPSSTSSAVASSSE 893
Query: 762 QSAR 765
S+R
Sbjct: 894 TSSR 897
Score = 67.8 bits (164), Expect = 6e-11
Identities = 115/441 (26%), Positives = 153/441 (34%), Gaps = 74/441 (16%)
Query: 34 SPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEET---NAPKKT 90
+P VST G + Q +A +A+ P + S E+ P T
Sbjct: 627 APPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSAT 686
Query: 91 KT--------EQELPRPQSPSDLDSLDGRSLNDDGS---SDPRDIDQDNRSTSPSIYSPG 139
T + LP+ +S L S +G L+ S S P QD +P G
Sbjct: 687 PTAILTQDSLQMFLPQERSQQPL-SAEGPHLSVPASVIVSAPPPA-QDPAPATPVAKGAG 744
Query: 140 SVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPH-PSVTPTGYHAPM 198
DS + + P P PL P P S P Q PH PS PT P
Sbjct: 745 LGPQAPDSQASPAPAPQIPA-AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPT--RPPS 801
Query: 199 EPPT-----SRMFQAPPGAPPPHPQLYPGGTG-----GVLSGPPMGPKGGGAASSVGGPN 248
PP+ SR PP P P PQ P G L PP P A ++ G P
Sbjct: 802 RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP--PASNPAPTAPGPPQ 859
Query: 249 G----------GKQHPPPTTPISVSSSGASGAPPTK---PPTTPVGGGNLPSAPPPANFP 295
G P P P S +SS + + T P TP + PP+ P
Sbjct: 860 PPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTP---SDFQLQFPPSQGP 916
Query: 296 HVTPNLPPPPALRPLNNASASPPG------LGAQPLPGHLPSPHAMGQGMGGLPPGPEKG 349
H +P PPP L + +A PP + P P LP P A+ + +P G
Sbjct: 917 HKSPT--PPPTLHLVPEPAAPPPPPPRTFQMVTTPFPA-LPQPKALLERFHQVPSGI--- 970
Query: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAA------SSSSSSSSSSASPFPASQ 403
L + APA P +S AA+ + S + ++ S +P PA
Sbjct: 971 --------ILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPM 1022
Query: 404 ALPSYPHSFPPPTSLSVSNQP 424
A P P SN P
Sbjct: 1023 AATGLPPLLPAENKAFASNLP 1043
Score = 51.6 bits (122), Expect = 4e-06
Identities = 84/374 (22%), Positives = 125/374 (33%), Gaps = 69/374 (18%)
Query: 314 SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF 373
S+S PG QP P HLP+ + G G P S+ A +S
Sbjct: 1228 SSSAPGASTQP-PPHLPTKLVIRHGGAGGSP-------------SVTWARAS-------- 1265
Query: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433
SS SSSS+++S++SS + P P+ P + L + + +
Sbjct: 1266 --SSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVH 1323
Query: 434 SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ--STAHPPVSTHHHHHQQQQQQQQ 491
+ A+ PPPPP +A P P PP TG + HPP + +++
Sbjct: 1324 NTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAA----PERKPLGTA 1379
Query: 492 QQQQQQQQQQQHHGNSGPP--PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHL 549
+ ++ + N G P P G GGS + G +R L
Sbjct: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439
Query: 550 -------PPPHSQVSYSQA-------GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQ 595
PPP S +Q P PP + S Q S+ P
Sbjct: 1440 YQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDD---- 1495
Query: 596 GAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPP 655
TL+ + + S + A P P A S G + PP
Sbjct: 1496 -----------------TLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGT-PASPPP 1537
Query: 656 GYKPGS-PPSFRTG 668
++P + PPS G
Sbjct: 1538 LHRPEAYPPSSHNG 1551
Score = 47.8 bits (112), Expect = 6e-05
Identities = 71/287 (24%), Positives = 95/287 (33%), Gaps = 45/287 (15%)
Query: 112 SLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLS------QGPARPYHPPPLF 165
S + SS +D D PS P ++ S GL G ++ H L
Sbjct: 1269 SSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALD 1328
Query: 166 PP-SPQPPDSTPRQPEASFEPHPSVTPTGYHAPM--EPPTSRMFQAPPGAPPPHPQLYPG 222
P P PP +T + E P P PTG PP + + P G P P+L
Sbjct: 1329 PVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLR 1388
Query: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA--------------- 267
T G P P+G A G GG P P + ++SG
Sbjct: 1389 KTYRENVGGPGAPEGTPA----GRARGGSPAPLPAK-VDEATSGLIRELAAVEDELYQRM 1443
Query: 268 -SGAPPTKPPTTPVGGGN----LPSAPPPANFPHVTPNLP--------PPPALRPLNNAS 314
G PP + G G+ P PP +P++ P + S
Sbjct: 1444 LKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQS 1503
Query: 315 ASPPGLGAQPLPGHLPSP---HAMGQGMGGLPPGPEKGPTLAPSPHS 358
A L Q PG P+P HA G PP + PS H+
Sbjct: 1504 AIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHN 1550
Score = 47.0 bits (110), Expect = 1e-04
Identities = 66/246 (26%), Positives = 82/246 (33%), Gaps = 45/246 (18%)
Query: 195 HAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHP 254
H P PP + PP PPP P G V PP P+ P G H
Sbjct: 1331 HQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPE--------RKPLGTAPHC 1382
Query: 255 P--PTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN 312
P P + G GAP P GG AP PA T L +
Sbjct: 1383 PRLPLRKTYRENVGGPGAPEGTPAGRARGGS---PAPLPAKVDEATSGL--------IRE 1431
Query: 313 ASASPPGLGAQPLPGHLPSPHA-MGQGMG-------GLPPGPEKGPTLAPSPHSLPPASS 364
+A L + L G P P A QG G GLPP + + SP + AS
Sbjct: 1432 LAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRR---KSESP-DVDQASF 1487
Query: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
S+ +P + S+ S + P PSYPH+ T S P
Sbjct: 1488 SSDSP--------QDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPAS----P 1535
Query: 425 PKYTQP 430
P +P
Sbjct: 1536 PPLHRP 1541
Score = 41.6 bits (96), Expect = 0.005
Identities = 99/415 (23%), Positives = 130/415 (31%), Gaps = 134/415 (32%)
Query: 357 HSLP---PASSSAPA----PPMRFPYS----------SSSSSSAAASSS---SSSSSSSA 396
H LP P SSSAP PP P S S + A ASSS SSSSSS+A
Sbjct: 1219 HRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAA 1278
Query: 397 SPFPASQALPSYPHSFPPPTSLSVSNQ---PPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453
S A + P + PP + ++ K Q + S+ V + P
Sbjct: 1279 SSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDP--------- 1329
Query: 454 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513
H P PP+T A PP PPPP
Sbjct: 1330 ---VHQPPPPPAT--LKVAEPPPR-------------------------------PPPP- 1352
Query: 514 AFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQ--AGPNGPPVSSS 571
P P + HP +P L P H P + +Y + GP P + +
Sbjct: 1353 --PPPTGQMNGTVDHPPPAAPERKPLGTAP----HCPRLPLRKTYRENVGGPGAPEGTPA 1406
Query: 572 SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631
+ G+P P P TS +I +A+
Sbjct: 1407 GRARG-------------------GSPAPLPAKVDEATSG-----LIRELAAVEDELYQR 1442
Query: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691
GPPP + + G T P PG PP+ R + SP +F SP
Sbjct: 1443 MLKGPPPEPAASAAQG---TGDPDWEAPGLPPAKRR------KSESPDVDQASFSSDSPQ 1493
Query: 692 VG-----------------------PGP-LPPAGPSGLPSLPPPPAAPASGPPLS 722
P P P A +G P+ PPP P + PP S
Sbjct: 1494 DDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSS 1548
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 102 bits (254), Expect = 2e-21
Identities = 157/651 (24%), Positives = 215/651 (33%), Gaps = 123/651 (18%)
Query: 152 SQGPARP-YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPP 210
S G + P Y P PP P P S A+ + G M + A
Sbjct: 374 SYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWA 433
Query: 211 GAPP-PHPQLYPGGTG---GVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
A HP + PG G G G PM P G + P ++P S G
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYG 493
Query: 267 ASGAPPTKPPTTPVG-GGNLPSAPPPANFPHVTPNLPPPPALRPLNN--ASASPPGLGAQ 323
G P P+G G P A +P +PP + ++ P Q
Sbjct: 494 PPG-----PQRYPIGIQGRTPGAMAGMQYPQ--QQMPPQYGQQGVSGYCQQGQQPYYSQQ 546
Query: 324 PLPGHLPSPHAM------------GQGMGGLPPGPEKGPTLAPS--------------PH 357
P P HLP P A Q M G P LAP P
Sbjct: 547 PQPPHLP-PQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPS 605
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
SLP S S P + SS+ SA+ S+SS S+ + P S PH+ P +S
Sbjct: 606 SLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFS------PHASPHLSS 659
Query: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST--GAQSTAHPP 475
+ G P P P G + ++ + GP P++ G+Q PP
Sbjct: 660 IP---------------------GGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPP 698
Query: 476 ----VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP--PGAFPHPLEGGSSHHA-H 528
S+ H Q Q++ Q+ GP P PHP GG H
Sbjct: 699 GSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGIS 758
Query: 529 PYAMSPSLGSLRPY-----PPGPAHLPPPHSQV-SYSQAGPNGPPVSSSSNSSSSTSQGS 582
+ S S G+ P P G PP +S V S S +GP GP + S+N+ S
Sbjct: 759 SFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGP-GPGMGISANNQMHGQGPS 817
Query: 583 YPC-------------------------SHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV 617
PC + SP QG P PP+PTV + +
Sbjct: 818 QPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAA 877
Query: 618 IATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
+ A++ A + S PG G A S P S P + + +
Sbjct: 878 VMQAAANSAQSRQGSFPGMNQSGLMASS------------SPYSQPMNNSSSLMNTQAPP 925
Query: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
P + +VG + G S LP LP G P ++ K+
Sbjct: 926 YSMAPAMVNSSAASVGLADMMSPGESKLP-LPLKADGKEEGTPQPESKSKK 975
Score = 86.3 bits (212), Expect = 2e-16
Identities = 120/488 (24%), Positives = 171/488 (35%), Gaps = 91/488 (18%)
Query: 149 SGLSQGPARPYHP----PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSR 204
SG Q +PY+ PP PP Q P Q + ++P ++ GY +PP +
Sbjct: 532 SGYCQQGQQPYYSQQPQPPHLPPQAQ---YLPSQSQQRYQPQQDMSQEGYGTRSQPPLA- 587
Query: 205 MFQAPPGAP---------PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG--GKQH 253
PG P P P +G + P +A S G G Q
Sbjct: 588 -----PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 642
Query: 254 PPPTTPISVSSS----GASGAPPTKPPTTPVGGGNLPSAP-PPANFPHVTPNLPPPPALR 308
P +P S +S G P P +PVG S P PA+ P +PP P
Sbjct: 643 NPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPG--SQMPPQPP-- 698
Query: 309 PLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP-SPHSLPPASSSAP 367
+ S+S P L P+P G G ++ P +A P P+ S P
Sbjct: 699 GSQSESSSHPALSQSPMPQER-----------GFMAGTQRNPQMAQYGPQQTGPSMSPHP 747
Query: 368 APPMRFPYSSSSSSSAAASSSSSSSSSSASPF------PASQALPSYPHSFPPPTSLSVS 421
+P + SS + +S + S P PA +PS +S P P +
Sbjct: 748 SPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISA 807
Query: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHH 481
N PS P AV P GR+ ++ PFP + + + + P +S
Sbjct: 808 NNQMHGQGPSQPCGAV---------PLGRM-PSAGMQNRPFPGNMSSMTPSSPGMSQQGG 857
Query: 482 HHQQQQQQQQQQQQQQQQQ--QQHHGNSGPPPPGAFP---------------HPLEGGSS 524
++ Q+ Q NS G+FP P+ SS
Sbjct: 858 PGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSS 917
Query: 525 ---HHAHPYAMSP--------SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN 573
A PY+M+P S+G PG + LP P + P P S S
Sbjct: 918 LMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQ--PESKSKK 975
Query: 574 SSSSTSQG 581
SSSST+ G
Sbjct: 976 SSSSTTTG 983
Score = 81.6 bits (200), Expect = 4e-15
Identities = 156/668 (23%), Positives = 200/668 (29%), Gaps = 112/668 (16%)
Query: 146 DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPR--QPEASFEPHPSVTPTGYHAPMEPPTS 203
DS++G G A P PP L P + D+ P+ +P HP + G P
Sbjct: 106 DSAAG---GQADPPGPPLLSKPGDED-DAPPKMGEPAGGRYEHPGLGALGTQQP------ 155
Query: 204 RMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG---------GKQHP 254
P PGG GG + P G AA + GGP G G Q
Sbjct: 156 -------------PVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQS 202
Query: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNN-- 312
P + +S+ A+GAP + P N P + H P P A
Sbjct: 203 PGMGMMHSASAAAAGAPGSMDPLQ-----NSHEGYPNSQCNHY-PGYSRPGAGGGGGGGG 256
Query: 313 --------------ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS 358
A A G GA + A G G GG G G + SP
Sbjct: 257 GGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYG-GSSAGYGVLSSPRQ 315
Query: 359 LPPASSSAPAPPMRFPYSSSSSSSAAAS----SSSSSSSSSASPFPASQALPSYPHSFPP 414
P S +++ SAA + + S A+P +Q L S P
Sbjct: 316 QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATP-TLNQLLTS-----PS 369
Query: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGP-------FPPSTG 467
P S P+Y+ PS P PPP P + A A G G
Sbjct: 370 PMMRSYGGSYPEYSSPSAPP-------PPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG 422
Query: 468 AQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-LEG-GSSH 525
AQ A P QQ+ P P P L G GS+
Sbjct: 423 AQYAAASPAWA-----AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP 477
Query: 526 HAHPYAMSPSLGSLRPYPPGPAHLP------PPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
H+ P SP G PPGP P P + PP S
Sbjct: 478 HSQPQQSSPYPGGSYG-PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQ 536
Query: 580 QGSYP--CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
QG P P P P A Y S + S GY T S P
Sbjct: 537 QGQQPYYSQQPQPPHLPPQAQY---------LPSQSQQRYQPQQDMSQEGYGTRSQPPLA 587
Query: 638 PYGKRAPSPGAYKTATPPGYKP--GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG 695
P + P GS TGT +G + +
Sbjct: 588 PGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQS 647
Query: 696 PLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVD 755
P P L S+P P+ G P+ + Q + P P S +P P PP +
Sbjct: 648 PFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMP----PQPPGSQSE 703
Query: 756 VPSHASQS 763
SH + S
Sbjct: 704 SSSHPALS 711
Score = 80.9 bits (198), Expect = 7e-15
Identities = 144/602 (23%), Positives = 196/602 (32%), Gaps = 97/602 (16%)
Query: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPV- 280
GG GG G G GGG + GG G + + G G V
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVL 310
Query: 281 -----GGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHLPSPHA 334
GG + P ++ A A + GA P L L SP
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
Query: 335 MGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAP---------------APPMRFPYSSSS 379
M + GG P P+ P P S P + ++A M Y+++S
Sbjct: 371 MMRSYGGSYP-EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAAS 429
Query: 380 SSSAAASSSSSSSSSSASPFPA---SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQA 436
+ AAA S + S +P P SQ P P P + + P Q S P
Sbjct: 430 PAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPG 489
Query: 437 VWSQGPPPPPPY-----GR---LLANSNAHPGPFPPSTGAQSTA---------------H 473
S GPP P Y GR +A PP G Q +
Sbjct: 490 -GSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQ 548
Query: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
PP + Q QQ+ Q QQ Q+ + S PP P+ + P ++
Sbjct: 549 PPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLP 608
Query: 534 PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP-SPSQ 592
GS+ P G ++ + S A S+S S+SS S P P SP
Sbjct: 609 DLSGSIDDLPTG--------TEATLSSA-------VSASGSTSSQGDQSNPAQSPFSPHA 653
Query: 593 GPQ-----GAPYPFP---PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
P G P P P PV + + S +S AS P PPG P
Sbjct: 654 SPHLSSIPGGPSPSPVGSPVGSNQSRSGPISP-----ASIPGSQMPPQPPGSQSESSSHP 708
Query: 645 SPGAYKTATPPGYKPG---SPPSFRTGTPPGYRGTSPPAGPG--------TFKPGSPTVG 693
+ G+ G +P + G SP PG +F+ + +
Sbjct: 709 ALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGT 768
Query: 694 PGP-LPPAGPSGLPSLPPP----PAAPAS--GPPLSATQIKQEPAEEYETPESPVPPARS 746
GP + GP G S PP P+A S GP + + Q + P VP R
Sbjct: 769 YGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRM 828
Query: 747 PS 748
PS
Sbjct: 829 PS 830
Score = 70.9 bits (172), Expect = 7e-12
Identities = 118/515 (22%), Positives = 175/515 (33%), Gaps = 104/515 (20%)
Query: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
PPP F T + P L+P SP G+ P +P + G PG K
Sbjct: 1091 PPPEVFS--TGDTKKQPKLQP-----PSPANSGSLQGP---QTPQSTGSNSMAEVPGDLK 1140
Query: 349 GPTLAPSPHS--LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS------------ 394
PT A +PH P + + P+S S SS +S + ++
Sbjct: 1141 PPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMG 1200
Query: 395 ------SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPY 448
+ PF + +P F + S+ Y Q + + G PY
Sbjct: 1201 RMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPY 1260
Query: 449 G-----RLLANSNAHPGPFPPST-----GAQSTAHPPVSTHHHH-----------HQQQQ 487
G R +PG PPS G Q +P + H H+
Sbjct: 1261 GASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDM 1320
Query: 488 QQQQQQQQQQQQQQQHHGN-SGP---PPPGAFPHP-----LEGGSSHHAH---------P 529
Q QQQ+ Q+ G+ SGP P G +P+P ++G H P
Sbjct: 1321 YNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGP 1380
Query: 530 YAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP---PVSSSSNSSSSTSQGSYPCS 586
S S G + +P P+ ++ GP GP P N + +
Sbjct: 1381 LQSSSSEGPQQNMWAARNDMPYPYQ----NRQGPGGPTQAPPYPGMNRTDDMMVPDQRIN 1436
Query: 587 HPS--PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
H S PS Q PY +SSA++ + + P +PP P + RAP
Sbjct: 1437 HESQWPSHVSQRQPY--------MSSSASMQPI-----TRPPQPSYQTPPSLPNHISRAP 1483
Query: 645 SPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
SP +++ + P P + T P S GP P PP P
Sbjct: 1484 SPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPT---------SQVTGPPPQPP--PIR 1532
Query: 705 LPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES 739
PP + AS P L Q ++ +++ TPE+
Sbjct: 1533 REITFPPGSVEASQPVLK--QRRKITSKDIVTPEA 1565
Score = 64.7 bits (156), Expect = 5e-10
Identities = 74/277 (26%), Positives = 94/277 (33%), Gaps = 60/277 (21%)
Query: 460 GPFPPSTGAQSTAHPPVSTHHHHHQ----------------QQQQQQQQQQQQQQQQQQH 503
G P + Q H + HHHHH QQQQQQQQQQQQQQQQQQH
Sbjct: 15 GEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQH 74
Query: 504 HGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGP 563
++ GA GG + P P G + G QA P
Sbjct: 75 PISNNNSLGGA------GGGAPQPGPDMEQPQHGGAKDSAAG-------------GQADP 115
Query: 564 NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV-----I 618
GPP+ S P P G Y P + + T ++
Sbjct: 116 PGPPLLSKPGDEDDA---------PPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGP 166
Query: 619 ATVASSPAGYKTASPPGPPPYGKRAP---------SPGAYKTATPPGYKPGSPPSF--RT 667
A V Y +A+P P G+ P SPG + G+P S
Sbjct: 167 AAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQ 226
Query: 668 GTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
+ GY + PG +PG+ G G G SG
Sbjct: 227 NSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSG 263
Score = 59.7 bits (143), Expect = 2e-08
Identities = 109/462 (23%), Positives = 156/462 (33%), Gaps = 100/462 (21%)
Query: 60 EEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSS 119
E ST KQ + + S + S P+ ++ + P DL S G
Sbjct: 1094 EVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPAS-TPHGQM 1152
Query: 120 DPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHP----PPLFPPSPQPPDST 175
P Q RS++ S++ P S +DS S P PY P + P P+
Sbjct: 1153 TPM---QGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKD 1209
Query: 176 P------------------RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP---- 213
P + P +S + + +P+G + + + F P GA
Sbjct: 1210 PFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQF--PYGASYDRR 1267
Query: 214 -PPHPQLYPGGTGGVLSGPPMG--PKGGGA-------------ASSVGGPNGGKQHPPPT 257
P+ Q YPG GPP G P GG + GP K+H
Sbjct: 1268 HEPYGQQYPG------QGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGP-PAKRHEGDM 1320
Query: 258 TPISVSSS-----GASGAPPTKPPTTPVGGGNLPSAPPPANFPHV-------TPNLPPPP 305
+ SS G + P P+ G P P + + T +PP
Sbjct: 1321 YNMQYSSQQQEMYNQYGGSYSGPDRRPIQG----QYPYPYSRERMQGPGQIQTHGIPPQM 1376
Query: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
PL ++S+ P +P P+ QG G GPT AP P+ +
Sbjct: 1377 MGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPG--------GPTQAP-PYPGMNRTDD 1427
Query: 366 APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF-----PASQALPSYPHSF---PPPTS 417
P R + S S + SSS+S P P+ Q PS P+ P P S
Sbjct: 1428 MMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPAS 1487
Query: 418 L--SVSNQPPKYTQPSLPSQAVWS----------QGPPPPPP 447
S+ N+ P LPS + GPPP PP
Sbjct: 1488 FQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPP 1529
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 102 bits (253), Expect = 3e-21
Identities = 182/777 (23%), Positives = 249/777 (32%), Gaps = 187/777 (24%)
Query: 59 VEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGS 118
VE P + K+ +E + + E N +E+ + D DGR +++G+
Sbjct: 298 VEPVGRPSILKEDNLKEFDQLDQE--NDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGA 355
Query: 119 SDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ 178
RD + P ++D G S + P P + + +PP++ P
Sbjct: 356 EGHRDSQSASGEERPP---------EADGKKGNSPN-SEPPTPKTAWAETSRPPETEPGP 405
Query: 179 PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP--- 235
P P P + P P P PPG P GPP P
Sbjct: 406 PA----PKPPLPP-----PHRGPAGNW--GPPGDYPDR------------GGPPCKPPAP 442
Query: 236 -----------KGGGAASSVGGPNGGKQHPPPTTPISVSSSGAS-----------GAPPT 273
K + S+ ++ + A GAP
Sbjct: 443 EDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDK 502
Query: 274 KPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPH 333
+ P PS P P P V LP PPA P P P+P
Sbjct: 503 RLKAEPAAPPAAPSTPAPP--PAVPKELPAPPA-----------------PPPASAPTPE 543
Query: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS 393
PE+ P PPA S+ P S S +++SS S +
Sbjct: 544 TE----------PEE-------PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEA 586
Query: 394 SSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453
S P S+ P P PPPT+ V PK GP PP L
Sbjct: 587 SPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGD----------GIGPTRQPPSQGL-- 634
Query: 454 NSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPP- 512
+P + PP Q+QQQ+Q +QQQQ Q QQH S PP P
Sbjct: 635 ---GYP--------KYQKSLPP------RFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPV 677
Query: 513 ----------GAFPHPLEGGSSHHAHPYAMSP-SLGSLRPYPP---GPAHLP-PPHSQVS 557
GA P P + P A+ P +LG P PP P + PP+
Sbjct: 678 PPSPPQPVTLGAVPAP----QAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPR 733
Query: 558 YSQAGP----NGPPVSSSS----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPP----VP 605
Q P P V S S S S P +P+ + P P V
Sbjct: 734 LLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVG 793
Query: 606 TVTTSSAT-----LSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATP------ 654
V T++ S + G ++ +PP PPP A PG + P
Sbjct: 794 DVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISR 853
Query: 655 -----PG-----YKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG 704
PG + PGS + TPP + P T + P G P G G
Sbjct: 854 FPLEEPGPRPLPWPPGSDEVAKIQTPPPKK---EPPKEETAQLTGPEAGRKPARGVGSGG 910
Query: 705 LPSLPPPPAAPASGP----PLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVP 757
PPPP + P + + P EE P P + P PP KV ++P
Sbjct: 911 --QGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELP 965
Score = 94.0 bits (232), Expect = 8e-19
Identities = 165/696 (23%), Positives = 218/696 (31%), Gaps = 183/696 (26%)
Query: 162 PPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYP 221
PP P +P PP + P++ A P P+ PT P EP QAPP P P
Sbjct: 511 PPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPA-----QAPPAQSTPTP---- 561
Query: 222 GGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTT--- 278
GV + P + GGG+ SS + G P P S G PPTT
Sbjct: 562 ----GVAAAPTL-VSGGGSTSST---SSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPV 613
Query: 279 ----PVGGGNLPSAPPPA---NFPHVTPNLPP---------------------------P 304
P G G P+ PP+ +P +LPP P
Sbjct: 614 PKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAP 673
Query: 305 PALRPLNNASASPPGLGAQPLP-GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS 363
P P+ + P LGA P P P P A+ G G PP P P +PP
Sbjct: 674 PT--PVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPP-PMPPMNFDPRWMMIPPYV 730
Query: 364 SS---APAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF----PAS-------------- 402
PP+ F S S S SS+ PF PA
Sbjct: 731 DPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLA 790
Query: 403 ------QALPSYPHSFPPPTSLSV--------SNQPP-KYTQPSLPSQAVWSQGPPPPPP 447
A P+ P P + S PP P L S + + P PP
Sbjct: 791 WVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPP 850
Query: 448 YGRL-LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN 506
R L P P+PP + + P ++ Q + ++ + G
Sbjct: 851 ISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGG 910
Query: 507 SGPPPPGA--------FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSY 558
GPPPP P P GSS P P P GP PPP ++V
Sbjct: 911 QGPPPPRRESRTETRWGPRP---GSSRRGIP----PEEPGAPPRRAGPIKKPPPPTKVEE 963
Query: 559 SQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVI 618
P P + P P P P T
Sbjct: 964 LP---------------------------PKPLEQGDETPKPPKPDPLKITKG------- 989
Query: 619 ATVASSPAGYKTASPPGPPPYGKRAPSPG-----AYKTATPPGYK-PGSPPSFRTGTPPG 672
K P PP G +P+P +Y+ P + G F G G
Sbjct: 990 ----------KLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGR--G 1037
Query: 673 YRGTSPPAGPG-------TFKPGSPTVGPGPLPPAGPSGLPSLPPPP-AAPASGPPLSAT 724
+RGT G G +++ G G G +G P+ PP P AS +
Sbjct: 1038 FRGTYGGRGRGARSREFRSYREFRGDDGRG-----GGTGGPNHPPAPRGRTASETRSEGS 1092
Query: 725 QIKQEPAEE--------YETPESPVPPARSPSPPPK 752
+ ++ P ET ES + P+ +P PK
Sbjct: 1093 EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPK 1128
Score = 86.3 bits (212), Expect = 2e-16
Identities = 219/989 (22%), Positives = 300/989 (30%), Gaps = 211/989 (21%)
Query: 166 PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP-------PPHPQ 218
PP P PP P F + + P P+E P R PPG+ PP +
Sbjct: 826 PPVPPPPPYLASYP--GFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKK 883
Query: 219 LYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS-------SGASGAP 271
P L+GP G K A VG +GG+ PPP + S G P
Sbjct: 884 EPPKEETAQLTGPEAGRK---PARGVG--SGGQGPPPPRRESRTETRWGPRPGSSRRGIP 938
Query: 272 PTKPPTTPVGGGNLPSAPPPANFPHVTPN-------LPPPPALRPLNNASASPPGLGAQP 324
P +P P G + PPP + P P PP PL G P
Sbjct: 939 PEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETP 998
Query: 325 LPGHL-PSPH------------------------AMGQGMGGLPPGPEKG---------- 349
G+L P+P A G+G G G +G
Sbjct: 999 PNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYR 1058
Query: 350 --------------PTLAPSPHSLPPASSSAPAP-----PMRFPYSSSSSSSAAASSSSS 390
P P+P + + + P R S + S S +
Sbjct: 1059 EFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLA 1118
Query: 391 SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPS--------LPSQAVWSQGP 442
S A P P L P + PPP S P ++T +PS+ G
Sbjct: 1119 PSDKEA-PTPKEGTLTQVPLA-PPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGR 1176
Query: 443 PPPP------PYGRLLANSNAHPGPFPPSTG-------------------------AQST 471
PPP P + LA GP PPS
Sbjct: 1177 PPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMED 1236
Query: 472 AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP---PGAFPHPLEGGSSHHAH 528
P H QQQ + + ++ +Q+++ G+ G P P + P P E ++
Sbjct: 1237 GERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTV--- 1293
Query: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
++ P P A P S + QA S SS+ +S
Sbjct: 1294 ---------TVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSER---------- 1334
Query: 589 SPSQGPQGAPYPFPPVP-TVTTSSATLSTVIATVASSPAG--YKTASPPGPPPYGKRAPS 645
+G + AP P P V T + +++ G + A + + P
Sbjct: 1335 ---RGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPG 1391
Query: 646 PGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGL 705
PG K GS S G G G + P SP P P P GL
Sbjct: 1392 MERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRP-PEERPPGL 1450
Query: 706 PSLPPPPAAPA---------SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756
P PPPP++ A S P I+Q A+ S P P P +
Sbjct: 1451 PLPPPPPSSSAVFRLDQVIHSNP----AGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQA 1506
Query: 757 PSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKE 816
P S ++ + NS SD +F ++ +V V A
Sbjct: 1507 PQGPSPRPP-TRYEPQRVNSGLSSDPHF---------EEPGPMVRGVGGTPRDSAGVSPF 1556
Query: 817 REREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYL 876
+ RER R +L QE P PP G + + P
Sbjct: 1557 PPKRRERP-----------PRKPELLQEESLP------------PPHSSG-FLGSKPEGP 1592
Query: 877 GPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAARERERE 936
GP + T +E PH+ NR H + + P D A E +
Sbjct: 1593 GPQAESRDTGTEALTPHIW---NRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQS 1649
Query: 937 ARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG---LALQP--GPPGLHPFPF 991
DL + P G+ G P R GG L P GPPG P P
Sbjct: 1650 DSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEP-PR 1708
Query: 992 HPSLGPLERERLALAAGPALRPDMSYAER 1020
P P + +R L L P ER
Sbjct: 1709 RPPPAPHDGDRKELPREQPLPPGPIGTER 1737
Score = 78.2 bits (191), Expect = 4e-14
Identities = 205/846 (24%), Positives = 281/846 (33%), Gaps = 163/846 (19%)
Query: 13 RSGRKKEAPGP------REELRSRGRASPGGVSTS---SSDGKAEK--SRQTAKKARVEE 61
R GR ++ P ++E + R S G S + S+ G E + A R
Sbjct: 1244 RHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAA 1303
Query: 62 ASTPKVNKQG--RSEEISESESEETNAPKKTKTEQELPRPQ--SPSDLDS--------LD 109
A +P ++ Q ++ E E+ SE ++ + + ++E P P +P + + +
Sbjct: 1304 AKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVP 1363
Query: 110 GRSLNDDGSSDPRDIDQDNRSTS---PSIY------SPGSVENDSDSSSGLS-------Q 153
G S G R D RS S P + PG S SSSG
Sbjct: 1364 GISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRT 1423
Query: 154 GPAR---------------PYHPPPLFPPSPQPPDSTPRQPEASFEPHPSV--TPTGYHA 196
GP R P PP P P PP S+ A F + P G
Sbjct: 1424 GPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSS-----AVFRLDQVIHSNPAGIQQ 1478
Query: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
+ +SR Q AP HP+ PG L P GP PP
Sbjct: 1479 ALAQLSSR--QGSVTAPGGHPRHKPG-----LPQAPQGPS---------------PRPPT 1516
Query: 257 TTPISVSSSGASGAPPTKPPTTPVGG--GNLPSAPPPANFPHVTPNLPP-PPALRPLNNA 313
+SG S P + P V G G + + FP PP P L L
Sbjct: 1517 RYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPEL--LQEE 1574
Query: 314 SASPPG----LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAP 369
S PP LG++P G P + G L P A S S P+S
Sbjct: 1575 SLPPPHSSGFLGSKP-EGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWME 1633
Query: 370 PMR-FPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYT 428
P+ F + + S + S S S S P SQ S P + PPK
Sbjct: 1634 PLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQ------RSSPDGGLKGAAEGPPKRP 1687
Query: 429 QPSLPSQAVWSQGPP--------PPPPYG----RLLANSNAHPGPFPPSTGAQS---TAH 473
S P AV +GPP PP P+ L PGP ++ T
Sbjct: 1688 GGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEP 1747
Query: 474 PPVSTHHHHHQQQQQQQQQQQQQQQ--------QQQQHHGNSGPPPPGAFPHPLEGGSSH 525
P+ H Q + + +++ + P + L ++
Sbjct: 1748 GPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAA 1807
Query: 526 HAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSS-NSSSSTSQGSY- 583
A P + + G P P P +V Y AGP+ +S + +S + G +
Sbjct: 1808 SAEPQSKNLDSGHCVPEPSSSGQRLYP--EVFYGSAGPSSSQISGGAMDSQLHPNSGGFR 1865
Query: 584 ---PCSHPSPSQGPQGAPYPFPPVPTVTTSSAT-----LSTVIAT-VASSPAG------- 627
P HP SQ P P PP ++ + ST+ AT + PAG
Sbjct: 1866 PGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPP 1925
Query: 628 ---YKTASPPGPPP------YGKRAPSPGA-YKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
Y A P P P + PSP Y T PG + G PS P +
Sbjct: 1926 SFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPS----GAPAQQMLL 1981
Query: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEE-YET 736
P P V G LPPA P P L P PA PP A + PA +
Sbjct: 1982 PMVDSQL-----PVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPS 2036
Query: 737 PESPVP 742
P P P
Sbjct: 2037 PARPFP 2042
Score = 76.3 bits (186), Expect = 2e-13
Identities = 166/768 (21%), Positives = 249/768 (32%), Gaps = 169/768 (22%)
Query: 16 RKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEE 75
R+ P L++ + + VS DG S+Q + +AST + + S+
Sbjct: 54 RRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPE---SQP 110
Query: 76 ISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSL----NDDGSSDPRDIDQDNRST 131
+ S++ +N PK+ E P PS + S S+ + DG + + +R
Sbjct: 111 LPASQTPASNQPKRPPAAPE-NTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREE 169
Query: 132 SPSIYSPGSVENDSDS--SSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSV 189
P++ + G + + S+ S GP PS +P +ST + P
Sbjct: 170 FPTLQAAGDQDKAAKERESAEQSSGPG----------PSLRPQNSTTWRDGGGRGPDE-- 217
Query: 190 TPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG 249
+E P S++ P L P SGPP P P
Sbjct: 218 --------LEGPDSKLHHGHD----PRGGLQP-------SGPPQFP-----------PYR 247
Query: 250 GKQHP---PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA 306
G P PP P PP P G P+ P+ FP V P
Sbjct: 248 GMMPPFMYPPYLPFP-------------PPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPP 294
Query: 307 LRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSA 366
+R L P L L G G + L S
Sbjct: 295 MR-LVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEE-------- 345
Query: 367 PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP--PPTSLSVSNQP 424
S A S S+S P A + P+S P P T+ + +++P
Sbjct: 346 -------DGRDSDEEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRP 398
Query: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQ 484
P+ T+P P+ PP PPP+ R A + PG +P G P Q
Sbjct: 399 PE-TEPGPPAPK-----PPLPPPH-RGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQ 451
Query: 485 QQQQ------------QQQQQQQQQQQQQQHH---------------------------- 504
+++Q ++++++++++ Q++
Sbjct: 452 RRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAP 511
Query: 505 --GNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAG 562
S P PP A P L A P S + P PA PP S + A
Sbjct: 512 PAAPSTPAPPPAVPKELP------APPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAA 565
Query: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA 622
P + S S+SSTS GS+ S P + P P VP TT
Sbjct: 566 --APTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVP--------K 615
Query: 623 SSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF-----RTGTPPGYRGTS 677
P G PP G P Y+ + PP ++ + +G++
Sbjct: 616 VEPKGDGIGPTRQPPSQGLGYPK---YQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSA 672
Query: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP----PAAPASGPPL 721
PP P T+G P P A P PPP P A PP+
Sbjct: 673 PPTPVPPSPPQPVTLGAVPAPQAPP------PPPKALYPGALGRPPPM 714
Score = 57.4 bits (137), Expect = 8e-08
Identities = 186/828 (22%), Positives = 248/828 (29%), Gaps = 167/828 (20%)
Query: 2 KTRQNKDSMSMRSG--RKKEAPGPREELRSRGRASPGG---VSTSSSDGKAEKSRQTAKK 56
K + S R G R+ PGP + S G +S GG + G+ +K + K
Sbjct: 1378 KDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPK 1437
Query: 57 --ARVEEASTPKV---------------------NKQGRSEEISESESEETNA------P 87
+R E P + N G + +++ S + + P
Sbjct: 1438 NRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHP 1497
Query: 88 KKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147
+ + P+ SP + + +N SSDP P + G DS
Sbjct: 1498 RHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHF-----EEPGPMVRGVGGTPRDS-- 1550
Query: 148 SSGLSQGPARPYHPPPLFP--------PSPQPPDSTPRQPEASFEPHPSVTPTGYHA--- 196
+G+S P + PP P P P +PE P TG A
Sbjct: 1551 -AGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGP-GPQAESRDTGTEALTP 1608
Query: 197 ----PMEPPTSRMFQAPPGAPPPHPQLYP--GGTGGVLSGPPMGPKGGGAASSVGGPNGG 250
+ TSR P P L P G +S G G + GP
Sbjct: 1609 HIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQ 1668
Query: 251 KQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL 310
+ P GA+ PP +P GG + +A P P P PPPA
Sbjct: 1669 RSSPDG------GLKGAAEGPPKRP-----GGSSPLNAVPCEGPPGSEPPRRPPPA---- 1713
Query: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGP---EKGPTLAPSPHSLPPASSSAP 367
P + LP P LPPGP E+ P S P
Sbjct: 1714 ------PHDGDRKELPREQP-----------LPPGPIGTERSQRTDRGTEPGPIRPSHRP 1756
Query: 368 APPMRFPYSSSSSS-------SAAASSSSSSSSSSASPFPAS-QALPSYPHSFPPPTSLS 419
PP++F S S S A ++S + A P + LPS S P +
Sbjct: 1757 GPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNL 1816
Query: 420 VSN----QPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHP--GPFPPSTGA----- 468
S +P Q P S GP G + +S HP G F P T +
Sbjct: 1817 DSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAM-DSQLHPNSGGFRPGTPSLHPYR 1875
Query: 469 -------QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP-----PGAFP 516
A P + Q Q + + G PPP P P
Sbjct: 1876 SQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCP 1935
Query: 517 HPLEGGSSHHAHPYAMSPSLGSLRPYPPG----------PAH---LPPPHSQVSYSQAG- 562
PL S SPS P PG PA LP SQ+ G
Sbjct: 1936 SPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGS 1995
Query: 563 -PNGPPVSSSSNSSSSTSQGSYPCS---HPSPSQGPQGAPYPFPPVPTVTTSSATLSTVI 618
P PP + S P S P P+ + P P P P + +
Sbjct: 1996 LPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPVEL 2055
Query: 619 ATVASSPAGYKTASPPGP---PPYG----------KRAPSP--GAYKTATPPGYKPGSPP 663
PG PP G K PS G ++T Y+ SPP
Sbjct: 2056 KPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPP 2115
Query: 664 SFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
P + T PP G P PG + P LPPP
Sbjct: 2116 DALRWIPKPWERTGPPPREG---PSRRAEEPG----SRGDKEPGLPPP 2156
Score = 57.0 bits (136), Expect = 1e-07
Identities = 160/687 (23%), Positives = 219/687 (31%), Gaps = 141/687 (20%)
Query: 354 PSPHSLPP--ASSSAPAPPMRF-PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPH 410
P P +LP A + P + P + +S S SS +S + P SQ LP+
Sbjct: 57 PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPA--- 113
Query: 411 SFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQS 470
+Q P QP P A + P P + A ++ G + G
Sbjct: 114 -----------SQTPASNQPKRPPAA--PENTPLVPSGVKSWAQASVTHG----AHGDGG 156
Query: 471 TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPP-------------GAFPH 517
A +S Q Q + ++++ +SGP P G P
Sbjct: 157 RASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPD 216
Query: 518 PLEGGSS--HHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVS---YSQAGPNGPPVSSSS 572
LEG S HH H G L+P GP PP + Y P PP
Sbjct: 217 ELEGPDSKLHHGHD-----PRGGLQP--SGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQG 269
Query: 573 NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATV----------- 621
T G P P + GP+G+ P V V S +
Sbjct: 270 PYRYPTPDG--PSRFPRVA-GPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGW 326
Query: 622 --ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP--GYRGTS 677
A Y G+ + GA G++ S P G +G S
Sbjct: 327 AGAHEEVDYTEKLKFSDEEDGRDSDEEGA------EGHRDSQSASGEERPPEADGKKGNS 380
Query: 678 PPAGPGTFKPG-SPTVGPGPLPPAGPSGLPSLPPPPAAPAS--GPPLSATQIKQEPAEEY 734
P + P T K + T P P P+ P LPPP PA GPP
Sbjct: 381 PNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPP-------------G 427
Query: 735 ETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAK 794
+ P+ PP + P+P + QS+ S++ LA
Sbjct: 428 DYPDRGGPPCKPPAPEDEDEAWRQRRKQSS---------------SEI--------SLAV 464
Query: 795 KRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSL 854
+RA + RRE E+R +E+ R E+ K R E+ +L E AP PS
Sbjct: 465 ERA----RRRREEEERRMQEERRAACAEKLK---RLDEKFGAPDKRLKAEPAAPPAAPS- 516
Query: 855 GPVPHRPPFEPGSAVA-TVPPYLGPDTPALRTLSEYARPHVMS---PGNRNHPFYVPLGA 910
P PP P A PP TP P S PG P V G
Sbjct: 517 --TPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGG 574
Query: 911 VDPGLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDP 970
+S ++ E E L + P P E+ P P P ++P
Sbjct: 575 -------------STSSTSSGSFEASPVEPQLPSKEGP---EPPEEVPPPTTPPVPKVEP 618
Query: 971 FPRHGGLALQPGPPGLHPFPFHPSLGP 997
G QP GL + SL P
Sbjct: 619 KGDGIGPTRQPPSQGLGYPKYQKSLPP 645
Score = 48.1 bits (113), Expect = 5e-05
Identities = 93/377 (24%), Positives = 122/377 (32%), Gaps = 93/377 (24%)
Query: 656 GYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGP-GPLPPAGPSGLPSLPPPPAA 714
G +P PP F P YRG PP + P P GP GP P G PS P A
Sbjct: 234 GLQPSGPPQF-----PPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDG-PSRFPRVAG 287
Query: 715 P-ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRG 773
P SGPP+ V P PS + + + + ++ D G
Sbjct: 288 PRGSGPPMRL-----------------VEPVGRPS-----ILKEDNLKEFDQLDQENDDG 325
Query: 774 FNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKER 833
+ A + D EK++ E+ R+ E E R+ + +ER
Sbjct: 326 WAG----------------AHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEER 369
Query: 834 ELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPH 893
E K +G +P P P P + A + PP P PA + PH
Sbjct: 370 PPEADGK---KGNSPNSEP---PTP-----KTAWAETSRPPETEPGPPAPK--PPLPPPH 416
Query: 894 VMSPGNRNHPFYVPLGAVDPGLLGYNVPALYSSDPAARE-----------------RERE 936
GN P P D G PA D A R+ R RE
Sbjct: 417 RGPAGNWGPPGDYP----DRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRRE 472
Query: 937 ARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPGLHPFPFHPSLG 996
ER +++ + K L+ G P L P PP P P
Sbjct: 473 EEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEP--------AAPPAAPSTPAPPPAV 524
Query: 997 PLERERLALAAGPALRP 1013
P E L A PA P
Sbjct: 525 PKE-----LPAPPAPPP 536
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 101 bits (251), Expect = 5e-21
Identities = 191/827 (23%), Positives = 266/827 (32%), Gaps = 187/827 (22%)
Query: 97 PRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPA 156
P P P D G+ SS + S + S +S G + GP
Sbjct: 512 PEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPL 571
Query: 157 RPYHPPPLFPPSPQPPDST---PRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
RP PPP P +T P P P +EPP + APP
Sbjct: 572 RP--PPPGAGGPATPSKATRFLPMDPATFRRKRPESV-----GGLEPPGPSVIAAPPSGG 624
Query: 214 ---------PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG----GKQHPPPTTPI 260
PP+ + GG V S P G A+ + P P +TP+
Sbjct: 625 GNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPV 684
Query: 261 SVSS-----SGASGAPPTK--------------PPTTPVGGGNLPSAPPPANFPHVTPNL 301
++S SG + A P P +P+G + S A P+L
Sbjct: 685 PIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHL 744
Query: 302 PPPPALRPLNNASAS-------PPGLGAQ------------------------------- 323
P L + A A+ PG GA
Sbjct: 745 VAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNG 804
Query: 324 PLPGHLPSPHAMGQGMGGLPPGPEKGPTL------APSPHSLPPASSSAPAPPMRFPYSS 377
P+P + P A+G+ GG+ PTL AP+P P ++AP+ P P +S
Sbjct: 805 PVPLGILQPGALGKA-GGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPA--PTTS 861
Query: 378 SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVS--NQPP---------- 425
+ +S++ ++ +P P L S P S PPP + SVS PP
Sbjct: 862 IRFTLPPGTSTNGKVLAATAPTPGIPILQSVP-SAPPPKAQSVSPVQAPPPGGSAQLLPG 920
Query: 426 KYTQP-SLPSQAVWSQGPPPP-----PPYGRLLANSNAHPG------PFPPSTGAQSTAH 473
K P + PS +V G P PP+ + N P P P ST S
Sbjct: 921 KVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVST--PSGLV 978
Query: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS 533
PP+S Q Q+ + P G P + G+ P S
Sbjct: 979 PPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGP-TSS 1037
Query: 534 PSLGSLRPYPPGPAHLPP--------------------PHSQVSYSQAGPNGPPVSSSSN 573
+LG P GPA + P P Q+ + A P GP +++ +
Sbjct: 1038 VALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYS 1097
Query: 574 SSSSTSQGSYPCSHPSP-SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTAS 632
S P+P S P P PP T +++T + P TA+
Sbjct: 1098 GS------------PAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATAT 1145
Query: 633 PPGPPPYGKRAPSPGAYKTATPPGYKPG--SPPSFR---TGTPPG--YRGTSPPAGPGTF 685
P P+ Y P +P +P + P G G S GP
Sbjct: 1146 PAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPR 1205
Query: 686 KPGSPTVGPGPLPPAGPSGLPSLPPPPAAP----------ASGPPLSATQIKQEPAEEYE 735
+P P GP P A S L P PPA P S PPL ++ A+ E
Sbjct: 1206 QPLEP--GPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPE 1263
Query: 736 TPESPVP------------------PARSPSPPPKVVDVPSHASQSA 764
T S P P PSP P P +S+S+
Sbjct: 1264 TMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESS 1310
Score = 80.5 bits (197), Expect = 9e-15
Identities = 180/759 (23%), Positives = 249/759 (32%), Gaps = 146/759 (19%)
Query: 79 SESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSP 138
S S+ + T E+ + + D D + DDG DID + S
Sbjct: 424 SRSQRAASEDMTSDEERMVICEEEGDDDVIA-----DDGFGTT-DIDLKCKERVTDSESG 477
Query: 139 GSVENDSDSSSGLSQGPARP-------YHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTP 191
S D + + G + P + PPL P P PPD P A + + S
Sbjct: 478 DSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPD----PPVAFGKGYGSAPS 533
Query: 192 TGYHAPMEPPTSRMFQAPPGAPPPHPQ-LYPGGTGGVLSGPPMGPKGGGAAS-------- 242
+ +P S G+ Q G T G L PP G G S
Sbjct: 534 SSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPM 593
Query: 243 -----------SVGGPNGGKQHPPPTTPISVSSSGASG------APPTKPPTTPVGGGNL 285
SVGG PP + I+ SG PP K GG +
Sbjct: 594 DPATFRRKRPESVGG-----LEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEG-GGARV 647
Query: 286 PSAPPPANFPHVTPNLPPPPALRP--------LNNASASPPGLGAQPLPGHLPSPHAMGQ 337
PSAP P+ + P P RP + S++P + ++P P
Sbjct: 648 PSAPAPS----LAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFP---------TS 694
Query: 338 GMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397
G P G S P S P+ S SAAA +S A
Sbjct: 695 GRAEASPNDTAGARTEMGTGSRVPGGS-----PLGVSLVYSDKKSAAA-------TSPAP 742
Query: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457
A L + + T+L V P Y P+ P+ +QG P A + +
Sbjct: 743 HLVAGPLLGTVGKAPATVTNLLVGT--PGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800
Query: 458 HP-GPFP---PSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPG 513
P GP P GA A + QQ Q + SGP P
Sbjct: 801 GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTT 860
Query: 514 AFPHPLEGGSSHHAHPYAM---SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSS 570
+ L G+S + A +P + L+ P P PP VS QA P G
Sbjct: 861 SIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAP---PPKAQSVSPVQAPPPG----- 912
Query: 571 SSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFP--------PVPTVTTSSATLSTVIATVA 622
++ + P + PS S GA P P PV + + +
Sbjct: 913 -GSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPV 971
Query: 623 SSPAG----YKTASPPGPPPYGKRAPSPGAYKT---------ATPPGYKPGSPPSFRTGT 669
S+P+G A+ PGP ++ P + + A P G SP S + GT
Sbjct: 972 STPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLG---TSPASSQAGT 1028
Query: 670 PPGYRGTSP---------PAGPGTFKP-----GSPTVGPGPLPPAGPSGLPSLPPPPAAP 715
Y TS P+GP +P +P + PG + G S +PS PPA
Sbjct: 1029 VTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQV---GVSPVPSPQLPPACA 1085
Query: 716 ASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVV 754
A G P+ PA P S P A+ PP +V
Sbjct: 1086 APGGPVITAFYSGSPA-----PTSSAPLAQPSQAPPSLV 1119
Score = 57.8 bits (138), Expect = 6e-08
Identities = 75/275 (27%), Positives = 93/275 (33%), Gaps = 79/275 (28%)
Query: 154 GPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAP 213
G P PL PS PP ++ P ++ P G PP AP A
Sbjct: 1098 GSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKG------PP------APATAT 1145
Query: 214 PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSS-------- 265
P +P T G ++ + PK Q P P P V ++
Sbjct: 1146 PAPTSPFPSATAGSMTYSLVAPKA--------------QRPSPKAPQKVKAAIASIPVGS 1191
Query: 266 ---GASGAP-----------PTKPPTTP---VGGGNLPSAPPP-----ANFPHVTPNLPP 303
GASG P P + PT P + G P APPP +P LPP
Sbjct: 1192 FEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPP 1251
Query: 304 PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMG--GLPPGPEKGPTLAPSPHSLPP 361
P R SA P A P GQG+ G PP P PSP
Sbjct: 1252 PAEER----TSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTP-------PSP----- 1295
Query: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSA 396
APAP + P SS SSS A+ + +A
Sbjct: 1296 ----APAPAVA-PGGSSESSSGRAAGDTPERKEAA 1325
Score = 51.6 bits (122), Expect = 4e-06
Identities = 108/442 (24%), Positives = 145/442 (32%), Gaps = 112/442 (25%)
Query: 378 SSSSSAAASSSSSSSSSSASPFPASQALPSYPHS-FPPPTSLSVSNQPPKYTQPSLPSQA 436
SS + A SSS + P S ++ HS V +Q + + A
Sbjct: 325 SSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPA 384
Query: 437 VWSQGPPPPPPYGRLLANSNAHPGPF--PPSTGA-QSTAHPPV-STHHHHHQQQQQQQQQ 492
+S GP P YG PGPF P GA +T PP+ T Q+ +
Sbjct: 385 SYS-GPKPSTQYGA--------PGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMT 435
Query: 493 QQQQQQQQQQHHGNSGPPPPGAFPHP------------LEGGSSHHAHPYA--------M 532
+++ + G+ F E G S P
Sbjct: 436 SDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVF 495
Query: 533 SPSLGS--------LRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584
SP + S L P PPGP P V++ + + P S+SS +SSS S
Sbjct: 496 SPVIRSSFTHCRPPLDPEPPGP-----PDPPVAFGKGYGSAPSSSASSPASSSAS----- 545
Query: 585 CSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644
+S +L + S G TA P PPP
Sbjct: 546 -----------------------AATSFSLGSGTFKAQESGQG-STAGPLRPPP------ 575
Query: 645 SPGAYKTATP---PGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPG------ 695
PGA ATP + P P +FR P G PP GP +P G G
Sbjct: 576 -PGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPP-GPSVI--AAPPSGGGNILQTL 631
Query: 696 PLPP------AGPSGLPSLPPP------PAAPASGPPLSATQIKQEPAEEYETPESPVPP 743
LPP G + +PS P P PAAP S P + P +PVP
Sbjct: 632 VLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVS-----STPVPI 686
Query: 744 ARSPSPPPKVVDVPSHASQSAR 765
A P P + + + AR
Sbjct: 687 ASKPFPTSGRAEASPNDTAGAR 708
Score = 46.6 bits (109), Expect = 1e-04
Identities = 48/163 (29%), Positives = 66/163 (40%), Gaps = 21/163 (12%)
Query: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS-PPAGPGTFKPGSP 690
S P P A P ++ A+ +P + PPG G++ P PG P SP
Sbjct: 47 SQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESP 106
Query: 691 TVGPGPLPPAGPSGLPSLPPPPA-APASGPPLSATQIKQEPAEEYE-------TPE--SP 740
GPGP P G PPP ASGPP ++ E +++ +PE P
Sbjct: 107 --GPGPPHPLGVVESGKGPPPTTEEEASGPP-GEPRLDSETESDHDDAFLSIMSPEIQLP 163
Query: 741 VPPAR----SPSPPPKVVDVPSH---ASQSARFNKHLDRGFNS 776
+PP + S S PK D S S + R H+ R N+
Sbjct: 164 LPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNA 206
Score = 39.7 bits (91), Expect = 0.017
Identities = 28/77 (36%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 207 QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
+ PPGA P P P GT P P GG +S +G Q PP P S G
Sbjct: 1526 EQPPGAEAPLPVPPPTGTAAA-PAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPG 1584
Query: 267 A---SGAP-PTKPPTTP 279
GAP P+ PP P
Sbjct: 1585 QPGWEGAPQPSPPPPGP 1601
Score = 39.3 bits (90), Expect = 0.023
Identities = 33/100 (33%), Positives = 36/100 (36%), Gaps = 20/100 (20%)
Query: 648 AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS 707
A T PPG + P TGT T PAG GP P P+ SG
Sbjct: 1522 ATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAG-----------GPDPTSPSSDSGTAQ 1570
Query: 708 LPPP-PAAPASGPPLSATQIKQEPAEEYETPESPVPPARS 746
PP P P SGP +P E SP PP S
Sbjct: 1571 AAPPLPPPPESGP--------GQPGWEGAPQPSPPPPGPS 1602
Score = 38.9 bits (89), Expect = 0.029
Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 14/100 (14%)
Query: 619 ATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSP 678
AT P G + P PP AP+P T +P G + PS +GT P
Sbjct: 1522 ATPTEQPPGAEAPLPVPPPTGTAAAPAP----TPSPAGGPDPTSPSSDSGTAQAAPPLPP 1577
Query: 679 PAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASG 718
P G +PG P P PP PP P+ A+G
Sbjct: 1578 PPESGPGQPGWEG-APQPSPP---------PPGPSTAATG 1607
Score = 37.4 bits (85), Expect = 0.086
Identities = 47/163 (28%), Positives = 58/163 (35%), Gaps = 27/163 (16%)
Query: 164 LFPPSPQPPDSTPRQPEASFEP----HPSVTPTGYHAPMEPPTSRMF---QAPPGAPPPH 216
+FP P P QP+ S +P P+ P + EP S + P G
Sbjct: 34 VFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSAD 93
Query: 217 PQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP 276
P+ PG T GP G +G GK PPPTT ASG PP
Sbjct: 94 PERPPGATCPESPGP-------GPPHPLGVVESGK-GPPPTT-----EEEASG-----PP 135
Query: 277 TTPVGGGNLPSAPPPANFPHVTP--NLPPPPALRPLNNASASP 317
P S A ++P LP PP R + SA P
Sbjct: 136 GEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALP 178
Score = 37.4 bits (85), Expect = 0.086
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 166 PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPT-SRMFQAPPGAPPPHPQLYPGGT 224
PP + P P + P P+ +P G P P + S QA P PPP P+ PG
Sbjct: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPP-PESGPGQP 1586
Query: 225 GGVLSGPPMGPKGGGAASSVG 245
G + P P G + ++ G
Sbjct: 1587 GWEGAPQPSPPPPGPSTAATG 1607
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/104 (26%), Positives = 36/104 (34%), Gaps = 23/104 (22%)
Query: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGA 648
+P++ P GA P P P P G A P P P G P+ +
Sbjct: 1523 TPTEQPPGAEAPLPVPP-------------------PTGTAAAPAPTPSPAGGPDPTSPS 1563
Query: 649 YKTATPPGYKPGSPPSFRTGTPPGYRG----TSPPAGPGTFKPG 688
+ T P PP PG+ G + PP GP T G
Sbjct: 1564 SDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATG 1607
Score = 36.6 bits (83), Expect = 0.15
Identities = 23/73 (31%), Positives = 27/73 (36%), Gaps = 13/73 (17%)
Query: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP------ 743
P PLP P+G + P P +PA GP T + P P PP
Sbjct: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSPAGGP--DPTSPSSDSGTAQAAPPLPPPPESGPGQ 1585
Query: 744 -----ARSPSPPP 751
A PSPPP
Sbjct: 1586 PGWEGAPQPSPPP 1598
Score = 35.4 bits (80), Expect = 0.33
Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 45/125 (36%)
Query: 343 PPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPAS 402
PPG E AP P P +++APAP + S A +S SS S + +
Sbjct: 1528 PPGAE-----APLPVPPPTGTAAAPAP---------TPSPAGGPDPTSPSSDSGT----A 1569
Query: 403 QALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPF 462
QA P P PPP S P P W P P PP PGP
Sbjct: 1570 QAAPPLP---PPPES-----------GPGQPG---WEGAPQPSPP----------PPGPS 1602
Query: 463 PPSTG 467
+TG
Sbjct: 1603 TAATG 1607
Score = 33.9 bits (76), Expect = 0.95
Identities = 29/101 (28%), Positives = 35/101 (34%), Gaps = 20/101 (19%)
Query: 251 KQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL 310
+Q P P+ V + A P P+ P GG + S + P LPPPP P
Sbjct: 1526 EQPPGAEAPLPVPPPTGTAAAPAPTPS-PAGGPDPTSPSSDSGTAQAAPPLPPPPESGP- 1583
Query: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT 351
PG P PSP PPGP T
Sbjct: 1584 -----GQPGWEGAP----QPSPP---------PPGPSTAAT 1606
Score = 33.5 bits (75), Expect = 1.2
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 21/133 (15%)
Query: 359 LPPASSSA-------------PAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL 405
L PASS+A P FP+ S A + S S A PAS +
Sbjct: 8 LMPASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQ-PASHPV 66
Query: 406 PSYPHSFPPPTSLSVSNQPPKYT---QPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPF 462
S P ++ +PP T P P A + P P PP+ + S G
Sbjct: 67 ASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVES----GKG 122
Query: 463 PPSTGAQSTAHPP 475
PP T + + PP
Sbjct: 123 PPPTTEEEASGPP 135
Score = 33.5 bits (75), Expect = 1.2
Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 20/81 (24%)
Query: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPG 647
P+P+ P G P P P SS +G A+PP PPP PG
Sbjct: 1547 PAPTPSPAGGPDPTSP-------------------SSDSGTAQAAPPLPPPPESGPGQPG 1587
Query: 648 AYKTATPPGYKPGSPPSFRTG 668
++ A P P P + TG
Sbjct: 1588 -WEGAPQPSPPPPGPSTAATG 1607
Score = 33.1 bits (74), Expect = 1.6
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 8/92 (8%)
Query: 174 STP-RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP 232
+TP QP + P P PTG A P S P G P P GT + PP
Sbjct: 1522 ATPTEQPPGAEAPLPVPPPTGTAAAPAPTPS-----PAGGPDPTSPSSDSGTAQ--AAPP 1574
Query: 233 MGPKGGGAASSVGGPNGGKQHPPPTTPISVSS 264
+ P G + PPP P + ++
Sbjct: 1575 LPPPPESGPGQPGWEGAPQPSPPPPGPSTAAT 1606
Score = 32.7 bits (73), Expect = 2.1
Identities = 23/72 (31%), Positives = 27/72 (37%), Gaps = 8/72 (11%)
Query: 409 PHSFPPPTSLSVSNQP-------PKYTQPSLPSQAVWSQGP-PPPPPYGRLLANSNAHPG 460
P PPPT + + P P T PS S + P PPPP G P
Sbjct: 1534 PLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQ 1593
Query: 461 PFPPSTGAQSTA 472
P PP G + A
Sbjct: 1594 PSPPPPGPSTAA 1605
Score = 32.3 bits (72), Expect = 2.8
Identities = 30/96 (31%), Positives = 33/96 (34%), Gaps = 20/96 (20%)
Query: 276 PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAM 335
PT G P PP P P PA P + +S G AQ P
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGT-AQAAP--------- 1573
Query: 336 GQGMGGLPPGPEKGPTL-----APSPHSLPPASSSA 366
LPP PE GP AP P PP S+A
Sbjct: 1574 -----PLPPPPESGPGQPGWEGAPQPSPPPPGPSTA 1604
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 100 bits (249), Expect = 8e-21
Identities = 172/705 (24%), Positives = 236/705 (33%), Gaps = 108/705 (15%)
Query: 114 NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF---PPSPQ 170
N +G++ PR +N T P PG S G A PPP + P +
Sbjct: 102 NSNGNAGPRPA-LNNNLTEP----PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGR 156
Query: 171 PPDSTPRQPEASFE--------PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP--QLY 220
P + A F P + +G +EP + P H Y
Sbjct: 157 SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYY 216
Query: 221 PGGTGG-------VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGAS----- 268
P + LS P G G GAA++ G PPP++ S SSS +S
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK------PPPSSSASASSSSSSFAQQR 270
Query: 269 -GAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG 327
GA P+ GG P+A P N +P+ P + S P GA P
Sbjct: 271 FGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPA 330
Query: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS-LPPASSSAPAPPM-RFPYSSSSSSSAAA 385
+ S G G S H+ + P SS P+ R P SS
Sbjct: 331 DMAS-QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGK 389
Query: 386 SSSSSSSSSSASPFPASQALPSYP---HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQG- 441
++ P+ Q PS P H +P +Q P+ ++ +A + G
Sbjct: 390 MRPQPYGGTN--PYSQQQGPPSGPQQGHGYP---GQPYGSQTPQRYPMTMQGRAQSAMGG 444
Query: 442 ---PPPPPPYGRLLANSNAHPG---------PFPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
PPYG+ + G P P + PP T H QQQ
Sbjct: 445 LSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP 504
Query: 490 QQQQQQQQQQQQQHHGNSGPPP----PGAFPHPLEGGSSH------HAHPYAMSPSLGSL 539
Q Q Q Q Q + PP P +P H ++ P A SP
Sbjct: 505 QSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP-YQQQ 563
Query: 540 RPYPPGPAHL------PPPHSQVS----YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589
+P P P+ L P P SQ S YSQ PP S S + S P S S
Sbjct: 564 QPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ--QRFPPPQELSQDSFGSQASSAP-SMTS 620
Query: 590 PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAY 649
G + P ++L + ++ P G + A PG G + S G
Sbjct: 621 SKGGQEDMNLSLQSRP------SSLPDLSGSIDDLPMGTEGALSPGVSTSG-ISSSQGEQ 673
Query: 650 KTATPPGYKPGSPPSFRTGTPPGYRGTSP-PAGPGTFKPGSPTVG-PGPLPPAGPSGLPS 707
+ P + P PG RG SP P G P S GPL PA G
Sbjct: 674 SNPAQSPFSPHTSPHL-----PGIRGPSPSPVG----SPASVAQSRSGPLSPAAVPGNQM 724
Query: 708 LPPPPAAPASG---PPLSATQIKQEPAEEYETPESPVPPARSPSP 749
P PP+ + P ++ + I Q+ P+ +P SP P
Sbjct: 725 PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ--MPQYSSPQP 767
Score = 97.8 bits (242), Expect = 5e-20
Identities = 178/712 (25%), Positives = 235/712 (33%), Gaps = 108/712 (15%)
Query: 21 PGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESE 80
P P L S +PG + +++ K S + + + + G +
Sbjct: 225 PAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284
Query: 81 SEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGS 140
T P T T +L SPS G D S P+D + G+
Sbjct: 285 G--TPQPTATPTLNQLLT--SPSSARGYQGYP-GGDYSGGPQDGGAGKGPADMASQCWGA 339
Query: 141 VENDSDSSSGLSQGPARPYHPPPLFPPSP----QPPDSTPRQPEASFEPHPSVTPTGYHA 196
+ +++ S G + H P+ P S QP TP QP + + + P Y
Sbjct: 340 AAAAA-AAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTP-QPSSPMDQMGKMRPQPYGG 397
Query: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
P S+ Q PP P YPG G + G A S G Q PP
Sbjct: 398 TN--PYSQQ-QGPPSGPQ-QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453
Query: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLP--SAPPPANFPHVTPNLPPPPALRPLNNAS 314
S G G P +P P S PP+ PH P+ P +P S
Sbjct: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513
Query: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374
+ PP P H SP P P + T P S PP S P + P
Sbjct: 514 SQPPYSQQPSQPPHQQSP----------APYPSQQSTTQQHPQSQPPYSQ----PQAQSP 559
Query: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS---FPPPTSLSVSNQPPKYTQPS 431
Y A S+ S + A P P SQ +S FPPP LS Q S
Sbjct: 560 YQQQQPQQPAPSTLSQQA---AYPQPQSQQSQQTAYSQQRFPPPQELS---------QDS 607
Query: 432 LPSQAVWSQGPPPPPPYGR---LLANSNAHPGPFPPSTGA--------QSTAHPPVSTHH 480
SQA S P G + + + P P +G+ + P VST
Sbjct: 608 FGSQA--SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSG 665
Query: 481 HHHQQQQQQQQQQQQQQQQQQQH-------------------HGNSGPPPPGAFP----- 516
Q +Q Q H SGP P A P
Sbjct: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMP 725
Query: 517 -HPLEGGSSHHAHPYAMSPSLGSLRPY----PPGPAH-LPPPHSQVSYSQAGPNGPPVSS 570
P G S HP S+ R Y P P + P P S +S Q P+G + +
Sbjct: 726 PRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQ--PSGGQIHT 783
Query: 571 SSNSSSSTSQGSYPCSHPSPSQ-GPQGAPYPFPP----VPTVTTSSATLSTVIATVASSP 625
S S GSY P Q GPQG YP P +P SA ++ I +
Sbjct: 784 GMGSYQQNSMGSY---GPQGGQYGPQGG-YPRQPNYNALPNANYPSAGMAGGINPMG--- 836
Query: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP---GSPPSFRTG--TPPG 672
AG + PG PPYG P ++ + Y P PP +G PPG
Sbjct: 837 AGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPG 888
Score = 67.8 bits (164), Expect = 6e-11
Identities = 150/640 (23%), Positives = 198/640 (30%), Gaps = 143/640 (22%)
Query: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220
PPP PPS ++ EA E + M+ + + P PP
Sbjct: 17 PPP--PPSELKKAEQQQREEAGGEA--AAAAAAERGEMKAAAGQESEGPAVGPPQ----- 67
Query: 221 PGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT--KPPTT 278
P G G GGG A S GGP P +S+G +G P T
Sbjct: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGA--------EPDLKNSNGNAGPRPALNNNLTE 119
Query: 279 PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA-------QPLPGHLPS 331
P GGG S+ PH PPPA SP + A Q G
Sbjct: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP 179
Query: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLP--------PASSSAPAPPMRFPYSS------ 377
A Q GG P GP H P P S+ P P + SS
Sbjct: 180 GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTP 239
Query: 378 -SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL---- 432
S +++AA S SSS+SAS +S A + S + P P+L
Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLL 299
Query: 433 --PSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ 490
PS A QG P Y + A GP ++ A +
Sbjct: 300 TSPSSARGYQGYPGGD-YSGGPQDGGAGKGPADMASQCWGAAAAAAAA------------ 346
Query: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP 550
QQ+ HH P G PL + P + +G +RP P G +
Sbjct: 347 -AAASGGAQQRSHHAPMSPGSSGGGGQPL----ARTPQPSSPMDQMGKMRPQPYGGTN-- 399
Query: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610
P+SQ Q P+GP QG P SQ PQ P
Sbjct: 400 -PYSQ---QQGPPSGP------------QQGHGYPGQPYGSQTPQRYPM----------- 432
Query: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
T+ S+ G PPYG++ PS GY + G
Sbjct: 433 -----TMQGRAQSAMGGLSYTQQI--PPYGQQGPS----------GYG-------QQGQT 468
Query: 671 PGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP 730
P Y SP PP P S P + +Q+P
Sbjct: 469 PYYNQQSPHPQQ------------------------QQPPYSQQPPSQTPHAQPSYQQQP 504
Query: 731 AEEYETPESPVPP-ARSPSPPPKVVDVPSHASQSARFNKH 769
+ +S PP ++ PS PP + SQ + +H
Sbjct: 505 QSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQH 544
Score = 63.9 bits (154), Expect = 9e-10
Identities = 131/585 (22%), Positives = 178/585 (30%), Gaps = 95/585 (16%)
Query: 65 PKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124
P +QG S + ++ N +Q+ P Q P S S P +
Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
Query: 125 DQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPP--DSTPRQPEAS 182
S P ++ + S S P PP P Q P P+QP
Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP--- 568
Query: 183 FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP--MGPKGGGA 240
P Y P + + + PPP +L G S P KGG
Sbjct: 569 -APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ-ELSQDSFGSQASSAPSMTSSKGGQE 626
Query: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN--FPHVT 298
++ + P + I G GA T+ + + P + PH +
Sbjct: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTS 686
Query: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG-LPPGPEKGPTLAPSPH 357
P+LP + S SP G SP ++ Q G L P G + P P
Sbjct: 687 PHLP------GIRGPSPSPVG-----------SPASVAQSRSGPLSPAAVPGNQMPPRPP 729
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
S S S P M SS + + +SP P S P P T
Sbjct: 730 S--GQSDSIMHPSMN---QSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784
Query: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
+ Y Q S+ S P Y R N NA P PS G +P
Sbjct: 785 MG------SYQQNSMGSYGPQGGQYGPQGGYPR-QPNYNALPNANYPSAGMAGGINP--- 834
Query: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYA-----M 532
Q HG G PP G P +S PY M
Sbjct: 835 -------------------MGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANM 875
Query: 533 SPSLGSLRPYPPGPAHLPPPHSQVSYSQAG---PNGPPVSSSSNSSSSTSQGSYPCSHPS 589
P +GS PPG + + V+ A N PP + N QG + P
Sbjct: 876 PPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMN------QGGMMGTGPP 929
Query: 590 PSQG---------PQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625
QG PQG PY + T++ A +A+SP
Sbjct: 930 YGQGINSMAGMINPQGPPY---------SMGGTMANNSAGMAASP 965
Score = 63.9 bits (154), Expect = 9e-10
Identities = 119/545 (21%), Positives = 172/545 (31%), Gaps = 100/545 (18%)
Query: 251 KQHPPPTTPISVSSSGASGAPPTKPPTTP--VGGGNLPSAPPPANFPHVTPNLPPPPALR 308
K+ P P S + SG+ P T T+ GG+L P PA+ PH +PP P +
Sbjct: 1124 KKSQPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDL-KPPTPASTPH--SQIPPLPGMS 1180
Query: 309 PLNNA-----------SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGP--TLAPS 355
N+ S P PG+ PS + MG + P K P ++ +
Sbjct: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDM-MGRMSYEPNKDPYGSMRKA 1239
Query: 356 PHSLPPASSS----------------------APAPPMRFPYSSSSSSSAAASSSSSSSS 393
P S P SS A P +PY +
Sbjct: 1240 PGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPGIGPEGN 1299
Query: 394 SSASPFPASQALPSYPHS-------FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446
S P +PS P S +PP + Y +Q S P P
Sbjct: 1300 MSTGA-PQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGN-QFSTQGTPSGSPFPSQ 1357
Query: 447 PYGRLLANSNAHPGPFPPSTGAQSTAHP------PVSTHHHHHQQQQ----------QQQ 490
+ P + G + H P ST QQQQ QQQ
Sbjct: 1358 QTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQQQ 1417
Query: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP 550
Q QQ +GN+ P A G + P+ S P ++P
Sbjct: 1418 AAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMP 1477
Query: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTS--QGSYPCSHPSPSQGPQGAPYPFPPVPTVT 608
P G P+ +S+ + + QG ++ ++ G+ P V
Sbjct: 1478 PQMM----------GGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVN 1527
Query: 609 TSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG 668
+ L T ++ G + PPYG AP P + P Y+P PPS +
Sbjct: 1528 RTDEMLHT---DQRANHEGSWPSHGTRQPPYGPSAPVPPMTR-PPPSNYQP--PPSMQNH 1581
Query: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLP-PAGPSGLPSLPPPPAAPASGPPLSATQIK 727
P + SP P P+ PS P L +GPP+ A+ I
Sbjct: 1582 IP---------------QVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIA 1626
Query: 728 QEPAE 732
P +
Sbjct: 1627 PAPVQ 1631
Score = 41.2 bits (95), Expect = 0.006
Identities = 81/374 (21%), Positives = 117/374 (31%), Gaps = 55/374 (14%)
Query: 127 DNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPH 186
D T P I G++ + + + P + P +PP Q +Q S+
Sbjct: 1286 DRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQ---QQQQQRHDSYGNQ 1342
Query: 187 PSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAAS---S 243
S T +P + M+Q Q Y G GPP G S S
Sbjct: 1343 FSTQGTPSGSPFPSQQTTMYQ-------QQQQNYKRPMDGTY-GPPAKRHEGEMYSVPYS 1394
Query: 244 VGGPNGGKQHPPPTTPISVSSSGASGAPPTK----------PPTTPVGGGNLPSAPPPAN 293
G +Q PP P S A+ P + P T P+ P
Sbjct: 1395 TGQGQPQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQ 1454
Query: 294 FPHV--TPNLPPPPALRPLNNASASPPGLGAQPL--PGHLPSPHAMGQGMGGLPPGPEKG 349
FP + PP N PP + P+ + M QG +
Sbjct: 1455 FPFQFGRDRVSAPPGTNAQQN---MPPQMMGGPIQASAEVAQQGTMWQGRNDMTYN---- 1507
Query: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSS---SSAAASSSSSSSSSSASPFPASQALP 406
++ ++ SAP P + + + A+ S S P + P
Sbjct: 1508 -------YANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAP 1560
Query: 407 SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPST 466
P + PPP++ QPP Q +P V S P P P R ++ PF S
Sbjct: 1561 VPPMTRPPPSNY----QPPPSMQNHIPQ--VSSPAPLPRPMENR----TSPSKSPFLHSG 1610
Query: 467 GAQSTAHPPVSTHH 480
A PPV H
Sbjct: 1611 MKMQKAGPPVPASH 1624
Score = 36.6 bits (83), Expect = 0.15
Identities = 84/382 (21%), Positives = 122/382 (31%), Gaps = 85/382 (22%)
Query: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475
+S + S+ +Y Q + +G PPP + + P PPS + P
Sbjct: 1085 SSSAASSLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAGSGSMQGP 1144
Query: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH----PLEGGSSHHAHPYA 531
Q Q G+ PP P + PH PL G S
Sbjct: 1145 ----------------QTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMS-------- 1180
Query: 532 MSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS 591
S S+G + G + ++ PN P S N+S + SY P+
Sbjct: 1181 RSNSVGIQDAFNDGSDSTFQKRNSMT-----PN-PGYQPSMNTSDMMGRMSY-----EPN 1229
Query: 592 QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG--PPPYGKRAPSPGAY 649
+ P G+ P S P P G PY RA PG
Sbjct: 1230 KDPYGSMRKAP-------------------GSDPFMSSGQGPNGGMGDPY-SRAAGPGLG 1269
Query: 650 KTAT-PPGYKPGSPPSFRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPLPPAGPSGLPS 707
A P + P P R T PG GP G G+P P +P SG+ S
Sbjct: 1270 NVAMGPRQHYPYGGPYDRVRTEPG-------IGPEGNMSTGAPQ--PNLMPSNPDSGMYS 1320
Query: 708 LPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFN 767
P+ PP Q +Q + P+ SP P + + Q +
Sbjct: 1321 -------PSRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTT---MYQQQQQNYK 1370
Query: 768 KHLDRGFNSCAR---SDLYFVP 786
+ +D + A+ ++Y VP
Sbjct: 1371 RPMDGTYGPPAKRHEGEMYSVP 1392
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 100 bits (249), Expect = 8e-21
Identities = 172/705 (24%), Positives = 236/705 (33%), Gaps = 108/705 (15%)
Query: 114 NDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLF---PPSPQ 170
N +G++ PR +N T P PG S G A PPP + P +
Sbjct: 102 NSNGNAGPRPA-LNNNLTEP----PGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGR 156
Query: 171 PPDSTPRQPEASFE--------PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHP--QLY 220
P + A F P + +G +EP + P H Y
Sbjct: 157 SPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYY 216
Query: 221 PGGTGG-------VLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGAS----- 268
P + LS P G G GAA++ G PPP++ S SSS +S
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSK------PPPSSSASASSSSSSFAQQR 270
Query: 269 -GAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG 327
GA P+ GG P+A P N +P+ P + S P GA P
Sbjct: 271 FGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPA 330
Query: 328 HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHS-LPPASSSAPAPPM-RFPYSSSSSSSAAA 385
+ S G G S H+ + P SS P+ R P SS
Sbjct: 331 DMAS-QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGK 389
Query: 386 SSSSSSSSSSASPFPASQALPSYP---HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQG- 441
++ P+ Q PS P H +P +Q P+ ++ +A + G
Sbjct: 390 MRPQPYGGTN--PYSQQQGPPSGPQQGHGYP---GQPYGSQTPQRYPMTMQGRAQSAMGG 444
Query: 442 ---PPPPPPYGRLLANSNAHPG---------PFPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
PPYG+ + G P P + PP T H QQQ
Sbjct: 445 LSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP 504
Query: 490 QQQQQQQQQQQQQHHGNSGPPP----PGAFPHPLEGGSSH------HAHPYAMSPSLGSL 539
Q Q Q Q Q + PP P +P H ++ P A SP
Sbjct: 505 QSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP-YQQQ 563
Query: 540 RPYPPGPAHL------PPPHSQVS----YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS 589
+P P P+ L P P SQ S YSQ PP S S + S P S S
Sbjct: 564 QPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQ--QRFPPPQELSQDSFGSQASSAP-SMTS 620
Query: 590 PSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAY 649
G + P ++L + ++ P G + A PG G + S G
Sbjct: 621 SKGGQEDMNLSLQSRP------SSLPDLSGSIDDLPMGTEGALSPGVSTSG-ISSSQGEQ 673
Query: 650 KTATPPGYKPGSPPSFRTGTPPGYRGTSP-PAGPGTFKPGSPTVG-PGPLPPAGPSGLPS 707
+ P + P PG RG SP P G P S GPL PA G
Sbjct: 674 SNPAQSPFSPHTSPHL-----PGIRGPSPSPVG----SPASVAQSRSGPLSPAAVPGNQM 724
Query: 708 LPPPPAAPASG---PPLSATQIKQEPAEEYETPESPVPPARSPSP 749
P PP+ + P ++ + I Q+ P+ +P SP P
Sbjct: 725 PPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ--MPQYSSPQP 767
Score = 97.8 bits (242), Expect = 5e-20
Identities = 178/712 (25%), Positives = 235/712 (33%), Gaps = 108/712 (15%)
Query: 21 PGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESE 80
P P L S +PG + +++ K S + + + + G +
Sbjct: 225 PAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGG 284
Query: 81 SEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGS 140
T P T T +L SPS G D S P+D + G+
Sbjct: 285 G--TPQPTATPTLNQLLT--SPSSARGYQGYP-GGDYSGGPQDGGAGKGPADMASQCWGA 339
Query: 141 VENDSDSSSGLSQGPARPYHPPPLFPPSP----QPPDSTPRQPEASFEPHPSVTPTGYHA 196
+ +++ S G + H P+ P S QP TP QP + + + P Y
Sbjct: 340 AAAAA-AAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTP-QPSSPMDQMGKMRPQPYGG 397
Query: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
P S+ Q PP P YPG G + G A S G Q PP
Sbjct: 398 TN--PYSQQ-QGPPSGPQ-QGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPP 453
Query: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLP--SAPPPANFPHVTPNLPPPPALRPLNNAS 314
S G G P +P P S PP+ PH P+ P +P S
Sbjct: 454 YGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQS 513
Query: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374
+ PP P H SP P P + T P S PP S P + P
Sbjct: 514 SQPPYSQQPSQPPHQQSP----------APYPSQQSTTQQHPQSQPPYSQ----PQAQSP 559
Query: 375 YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS---FPPPTSLSVSNQPPKYTQPS 431
Y A S+ S + A P P SQ +S FPPP LS Q S
Sbjct: 560 YQQQQPQQPAPSTLSQQA---AYPQPQSQQSQQTAYSQQRFPPPQELS---------QDS 607
Query: 432 LPSQAVWSQGPPPPPPYGR---LLANSNAHPGPFPPSTGA--------QSTAHPPVSTHH 480
SQA S P G + + + P P +G+ + P VST
Sbjct: 608 FGSQA--SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSG 665
Query: 481 HHHQQQQQQQQQQQQQQQQQQQH-------------------HGNSGPPPPGAFP----- 516
Q +Q Q H SGP P A P
Sbjct: 666 ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMP 725
Query: 517 -HPLEGGSSHHAHPYAMSPSLGSLRPY----PPGPAH-LPPPHSQVSYSQAGPNGPPVSS 570
P G S HP S+ R Y P P + P P S +S Q P+G + +
Sbjct: 726 PRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQ--PSGGQIHT 783
Query: 571 SSNSSSSTSQGSYPCSHPSPSQ-GPQGAPYPFPP----VPTVTTSSATLSTVIATVASSP 625
S S GSY P Q GPQG YP P +P SA ++ I +
Sbjct: 784 GMGSYQQNSMGSY---GPQGGQYGPQGG-YPRQPNYNALPNANYPSAGMAGGINPMG--- 836
Query: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP---GSPPSFRTG--TPPG 672
AG + PG PPYG P ++ + Y P PP +G PPG
Sbjct: 837 AGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPG 888
Score = 67.8 bits (164), Expect = 6e-11
Identities = 150/640 (23%), Positives = 198/640 (30%), Gaps = 143/640 (22%)
Query: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLY 220
PPP PPS ++ EA E + M+ + + P PP
Sbjct: 17 PPP--PPSELKKAEQQQREEAGGEA--AAAAAAERGEMKAAAGQESEGPAVGPPQ----- 67
Query: 221 PGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPT--KPPTT 278
P G G GGG A S GGP P +S+G +G P T
Sbjct: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGA--------EPDLKNSNGNAGPRPALNNNLTE 119
Query: 279 PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGA-------QPLPGHLPS 331
P GGG S+ PH PPPA SP + A Q G
Sbjct: 120 PPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSP 179
Query: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLP--------PASSSAPAPPMRFPYSS------ 377
A Q GG P GP H P P S+ P P + SS
Sbjct: 180 GLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGTP 239
Query: 378 -SSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL---- 432
S +++AA S SSS+SAS +S A + S + P P+L
Sbjct: 240 GSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLL 299
Query: 433 --PSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ 490
PS A QG P Y + A GP ++ A +
Sbjct: 300 TSPSSARGYQGYPGGD-YSGGPQDGGAGKGPADMASQCWGAAAAAAAA------------ 346
Query: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP 550
QQ+ HH P G PL + P + +G +RP P G +
Sbjct: 347 -AAASGGAQQRSHHAPMSPGSSGGGGQPL----ARTPQPSSPMDQMGKMRPQPYGGTN-- 399
Query: 551 PPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTS 610
P+SQ Q P+GP QG P SQ PQ P
Sbjct: 400 -PYSQ---QQGPPSGP------------QQGHGYPGQPYGSQTPQRYPM----------- 432
Query: 611 SATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTP 670
T+ S+ G PPYG++ PS GY + G
Sbjct: 433 -----TMQGRAQSAMGGLSYTQQI--PPYGQQGPS----------GYG-------QQGQT 468
Query: 671 PGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP 730
P Y SP PP P S P + +Q+P
Sbjct: 469 PYYNQQSPHPQQ------------------------QQPPYSQQPPSQTPHAQPSYQQQP 504
Query: 731 AEEYETPESPVPP-ARSPSPPPKVVDVPSHASQSARFNKH 769
+ +S PP ++ PS PP + SQ + +H
Sbjct: 505 QSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQH 544
Score = 63.9 bits (154), Expect = 9e-10
Identities = 131/585 (22%), Positives = 178/585 (30%), Gaps = 95/585 (16%)
Query: 65 PKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI 124
P +QG S + ++ N +Q+ P Q P S S P +
Sbjct: 452 PPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQL 511
Query: 125 DQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPP--DSTPRQPEAS 182
S P ++ + S S P PP P Q P P+QP
Sbjct: 512 QSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQP--- 568
Query: 183 FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP--MGPKGGGA 240
P Y P + + + PPP +L G S P KGG
Sbjct: 569 -APSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ-ELSQDSFGSQASSAPSMTSSKGGQE 626
Query: 241 ASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN--FPHVT 298
++ + P + I G GA T+ + + P + PH +
Sbjct: 627 DMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTS 686
Query: 299 PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG-LPPGPEKGPTLAPSPH 357
P+LP + S SP G SP ++ Q G L P G + P P
Sbjct: 687 PHLP------GIRGPSPSPVG-----------SPASVAQSRSGPLSPAAVPGNQMPPRPP 729
Query: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
S S S P M SS + + +SP P S P P T
Sbjct: 730 S--GQSDSIMHPSMN---QSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784
Query: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
+ Y Q S+ S P Y R N NA P PS G +P
Sbjct: 785 MG------SYQQNSMGSYGPQGGQYGPQGGYPR-QPNYNALPNANYPSAGMAGGINP--- 834
Query: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYA-----M 532
Q HG G PP G P +S PY M
Sbjct: 835 -------------------MGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANM 875
Query: 533 SPSLGSLRPYPPGPAHLPPPHSQVSYSQAG---PNGPPVSSSSNSSSSTSQGSYPCSHPS 589
P +GS PPG + + V+ A N PP + N QG + P
Sbjct: 876 PPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMN------QGGMMGTGPP 929
Query: 590 PSQG---------PQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625
QG PQG PY + T++ A +A+SP
Sbjct: 930 YGQGINSMAGMINPQGPPY---------SMGGTMANNSAGMAASP 965
Score = 58.5 bits (140), Expect = 4e-08
Identities = 186/869 (21%), Positives = 278/869 (31%), Gaps = 143/869 (16%)
Query: 60 EEASTPKVNKQGRSEEISESESEETN---APKKTKTEQELP--RPQSPSDLDSLDGRSLN 114
E A +P V+ G IS S+ E++N +P T LP R SPS + S + +
Sbjct: 654 EGALSPGVSTSG----ISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQS 709
Query: 115 DDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDS 174
G P + + P S+ + S + S ++Q R Y +PQ P
Sbjct: 710 RSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQD--RGY-----MQRNPQMPQY 762
Query: 175 TPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG 234
+ QP ++ P P+G + Q G+ P GG G G P
Sbjct: 763 SSPQPGSALSPRQ---PSG--GQIHTGMGSYQQNSMGSYGPQ-----GGQYGPQGGYPRQ 812
Query: 235 PKGGG-------AASSVGGPN----GGKQHPPPTTPISVSSSGASGAPP--TKPP--TTP 279
P +A GG N GG+ H P G PP T PP +
Sbjct: 813 PNYNALPNANYPSAGMAGGINPMGAGGQMHGQP------------GIPPYGTLPPGRMSH 860
Query: 280 VGGGNLPSAPPPANFPHVTPN--LPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQ 337
GN P P AN P + PPP + +A + A + P M Q
Sbjct: 861 ASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQ 920
Query: 338 GMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397
G G + GP G + + P PP + +++S+ A+S
Sbjct: 921 G-GMMGTGPPYGQGINSMAGMINPQG-----PPYSMGGTMANNSAGMAASPEMMGLGDVK 974
Query: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457
PA++ + + P S S + T + P R LA +
Sbjct: 975 LTPATK-MNNKADGTPKTESKSKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEE 1033
Query: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQ-----QQQQQQQQQQQQQQQHHGNSGPPPP 512
T + P+ + + ++ Q + ++ ++ + G S
Sbjct: 1034 KAMGM---TNLPAVGRKPLDLYRLYVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAAS 1090
Query: 513 G----------AFPHPLEGGSSHHAHPYAMSPSLGSL-RPYPPGPAHLPPPHSQVSYSQA 561
AF +E G +A + S S + PP PA S S
Sbjct: 1091 SLKKQYIQCLYAFECKIERGEDPPPDIFAAADSKKSQPKIQPPSPAG--------SGSMQ 1142
Query: 562 GPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATV 621
GP P +SSS + + P S P PP+P ++ S++
Sbjct: 1143 GPQTPQSTSSSMAEGGDLKPPTPASTPHSQ---------IPPLPGMSRSNSVGIQDAFND 1193
Query: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPG-----YRGT 676
S K S P Y PS Y+P P PG G
Sbjct: 1194 GSDSTFQKRNSMTPNPGY---QPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQ 1250
Query: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEP--AEEY 734
P G G P S GPG G ++ P P GP +++ EP E
Sbjct: 1251 GPNGGMG--DPYSRAAGPG-------LGNVAMGPRQHYPYGGP---YDRVRTEPGIGPEG 1298
Query: 735 ETPESPVPPARSPSPPPKVVDVPSH---ASQSARFNKHLDRGFNSCARSDLYFVPLEGSK 791
P PS P + PS Q + +H G + GS
Sbjct: 1299 NMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQG-----TPSGSP 1353
Query: 792 LAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVEC 851
++ + +Q+ + R E K L +K+ + G PV
Sbjct: 1354 FPSQQTTMY-------QQQQQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKAG-PPVPA 1405
Query: 852 PSLGPVPHRPP-------FEPGSAVATVP 873
+ P P +PP F PGS AT P
Sbjct: 1406 SHIAPAPVQPPMIRRDITFPPGSVEATQP 1434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.129 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,160,451
Number of Sequences: 37866
Number of extensions: 6356628
Number of successful extensions: 148920
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1474
Number of HSP's successfully gapped in prelim test: 3399
Number of HSP's that attempted gapping in prelim test: 36426
Number of HSP's gapped (non-prelim): 54527
length of query: 1190
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1076
effective length of database: 13,930,794
effective search space: 14989534344
effective search space used: 14989534344
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.