Guide to the Human Genome
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Search of human proteins with 55749504

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55749504 syntenin isoform 2 [Homo sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55749504 syntenin isoform 2 [Homo sapiens]                         574   e-164
gi|55749490 syntenin isoform 1 [Homo sapiens]                         568   e-162
gi|56243522 syntenin isoform 1 [Homo sapiens]                         568   e-162
gi|55749523 syntenin isoform 3 [Homo sapiens]                         561   e-160
gi|55749515 syntenin isoform 3 [Homo sapiens]                         561   e-160
gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens]      333   1e-91
gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens]       298   3e-81
gi|22035548 amyloid beta A4 precursor protein-binding, family A,...    62   5e-10
gi|194353992 amyloid beta A4 precursor protein-binding, family A...    61   1e-09
gi|22035550 amyloid beta A4 precursor protein-binding, family A,...    61   1e-09
gi|11342678 amyloid beta (A4) precursor protein-binding, family ...    57   2e-08
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           49   7e-06
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           49   7e-06
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi...    47   2e-05
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi...    47   2e-05
gi|45827729 scribble isoform b [Homo sapiens]                          45   1e-04
gi|45827731 scribble isoform a [Homo sapiens]                          45   1e-04
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]                      44   1e-04
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]                      44   1e-04
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]                       44   1e-04
gi|11993943 Tax1 binding protein 3 [Homo sapiens]                      44   2e-04
gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo...    43   3e-04
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi...    43   4e-04
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa...    43   4e-04
gi|21361142 PDZ domain containing 1 [Homo sapiens]                     43   4e-04
gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchan...    42   5e-04
gi|148833504 interleukin 16 isoform 2 [Homo sapiens]                   42   5e-04
gi|9507163 syntrophin, gamma 1 [Homo sapiens]                          42   5e-04
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]     42   5e-04
gi|95089461 discs large homolog 5 [Homo sapiens]                       42   8e-04

>gi|55749504 syntenin isoform 2 [Homo sapiens]
          Length = 292

 Score =  574 bits (1480), Expect = e-164
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MSLYPSLEDLKAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEI 60
           MSLYPSLEDLKAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEI
Sbjct: 1   MSLYPSLEDLKAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEI 60

Query: 61  RANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIG 120
           RANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIG
Sbjct: 61  RANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIG 120

Query: 121 LRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKI 180
           LRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKI
Sbjct: 121 LRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKI 180

Query: 181 TMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNV 240
           TMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNV
Sbjct: 181 TMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNV 240

Query: 241 IGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 292
           IGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 241 IGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 292


>gi|55749490 syntenin isoform 1 [Homo sapiens]
          Length = 298

 Score =  568 bits (1463), Expect = e-162
 Identities = 292/298 (97%), Positives = 292/298 (97%), Gaps = 6/298 (2%)

Query: 1   MSLYPSLEDLK------AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 54
           MSLYPSLEDLK      AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1   MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60

Query: 55  LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 114
           LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61  LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120

Query: 115 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 174
           QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180

Query: 175 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 234
           AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240

Query: 235 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 292
           INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298


>gi|56243522 syntenin isoform 1 [Homo sapiens]
          Length = 298

 Score =  568 bits (1463), Expect = e-162
 Identities = 292/298 (97%), Positives = 292/298 (97%), Gaps = 6/298 (2%)

Query: 1   MSLYPSLEDLK------AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 54
           MSLYPSLEDLK      AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1   MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60

Query: 55  LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 114
           LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61  LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 120

Query: 115 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 174
           QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 121 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 180

Query: 175 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 234
           AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 181 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 240

Query: 235 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 292
           INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 241 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 298


>gi|55749523 syntenin isoform 3 [Homo sapiens]
          Length = 297

 Score =  561 bits (1446), Expect = e-160
 Identities = 291/298 (97%), Positives = 291/298 (97%), Gaps = 7/298 (2%)

Query: 1   MSLYPSLEDLK------AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 54
           MSLYPSLEDLK      AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1   MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60

Query: 55  LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 114
           LNEEEIRANVAVVSGAPLQG LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61  LNEEEIRANVAVVSGAPLQG-LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 119

Query: 115 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 174
           QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 120 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 179

Query: 175 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 234
           AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 180 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 239

Query: 235 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 292
           INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 240 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 297


>gi|55749515 syntenin isoform 3 [Homo sapiens]
          Length = 297

 Score =  561 bits (1446), Expect = e-160
 Identities = 291/298 (97%), Positives = 291/298 (97%), Gaps = 7/298 (2%)

Query: 1   MSLYPSLEDLK------AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 54
           MSLYPSLEDLK      AQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS
Sbjct: 1   MSLYPSLEDLKVDKVIQAQTAFSANPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLS 60

Query: 55  LNEEEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 114
           LNEEEIRANVAVVSGAPLQG LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD
Sbjct: 61  LNEEEIRANVAVVSGAPLQG-LVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKD 119

Query: 115 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 174
           QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ
Sbjct: 120 QDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ 179

Query: 175 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 234
           AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE
Sbjct: 180 AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICE 239

Query: 235 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 292
           INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV
Sbjct: 240 INGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPEV 297


>gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens]
          Length = 292

 Score =  333 bits (853), Expect = 1e-91
 Identities = 169/294 (57%), Positives = 222/294 (75%), Gaps = 9/294 (3%)

Query: 2   SLYPSLEDLKAQTAFSA----NPANPAILSEASAPIPHDGNLYPRLYPELSQYMGLSLNE 57
           SLYPSLEDLK   A  A    +P  PA+  +A+A  P    LYP L  EL  YMGLSL+ 
Sbjct: 3   SLYPSLEDLKVDQAIQAQVRASPKMPALPVQATAISPPPV-LYPNL-AELENYMGLSLSS 60

Query: 58  EEIRANVAVVSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDG 117
           +E++ ++  +         V+ P     MVAPVTG  +G+RRAEIK G+RE+ LCKD+ G
Sbjct: 61  QEVQESLLQIPEG--DSTAVSGPGP-GQMVAPVTGYSLGVRRAEIKPGVREIHLCKDERG 117

Query: 118 KIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFG 177
           K GLRL+ +D G+FVQLVQAN+PASLVGLRFGDQ+LQI+G +CAGWSS KAH+V+K+A G
Sbjct: 118 KTGLRLRKVDQGLFVQLVQANTPASLVGLRFGDQLLQIDGRDCAGWSSHKAHQVVKKASG 177

Query: 178 EKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEING 237
           +KI + +RDRPF+RT+TMHKDS GHVGF+ K GKI S+VK SSAARNGLLT H +CE++G
Sbjct: 178 DKIVVVVRDRPFQRTVTMHKDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEVDG 237

Query: 238 QNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMDHTIPE 291
           QNVIGLKD +I +IL+T+G VVT+TI+P+ I+EH++K++ P ++   MDH+IP+
Sbjct: 238 QNVIGLKDKKIMEILATAGNVVTLTIIPSVIYEHMVKKLPPVLLHHTMDHSIPD 291


>gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens]
          Length = 207

 Score =  298 bits (764), Expect = 3e-81
 Identities = 136/206 (66%), Positives = 177/206 (85%)

Query: 86  MVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVG 145
           MVAPVTG  +G+RRAEIK G+RE+ LCKD+ GK GLRL+ +D G+FVQLVQAN+PASLVG
Sbjct: 1   MVAPVTGYSLGVRRAEIKPGVREIHLCKDERGKTGLRLRKVDQGLFVQLVQANTPASLVG 60

Query: 146 LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFERTITMHKDSTGHVGF 205
           LRFGDQ+LQI+G +CAGWSS KAH+V+K+A G+KI + +RDRPF+RT+TMHKDS GHVGF
Sbjct: 61  LRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVVVVRDRPFQRTVTMHKDSMGHVGF 120

Query: 206 IFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMP 265
           + K GKI S+VK SSAARNGLLT H +CE++GQNVIGLKD +I +IL+T+G VVT+TI+P
Sbjct: 121 VIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAGNVVTLTIIP 180

Query: 266 AFIFEHIIKRMAPSIMKSLMDHTIPE 291
           + I+EH++K++ P ++   MDH+IP+
Sbjct: 181 SVIYEHMVKKLPPVLLHHTMDHSIPD 206


>gi|22035548 amyloid beta A4 precursor protein-binding, family A,
           member 1 [Homo sapiens]
          Length = 837

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 41/152 (26%), Positives = 70/152 (46%), Gaps = 3/152 (1%)

Query: 130 IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTI-RD 186
           + +  +    PA   G L  GDQ++ ING +  G        ++K    + ++ + I R 
Sbjct: 683 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRC 742

Query: 187 RPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDS 246
            P    +    D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     
Sbjct: 743 PPVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHE 802

Query: 247 QIADILSTSGTVVTITIMPAFIFEHIIKRMAP 278
           +I  ILS +   + +  MPA ++  +  +  P
Sbjct: 803 KIVHILSNAVGEIHMKTMPAAMYRLLTAQEQP 834


>gi|194353992 amyloid beta A4 precursor protein-binding, family A,
           member 2 isoform b [Homo sapiens]
          Length = 737

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)

Query: 140 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 197
           PA+  G L  GDQ++ ING +  G        ++K    + ++ + I   P   T+ + +
Sbjct: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652

Query: 198 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 256
            D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     +I   LS S 
Sbjct: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712

Query: 257 TVVTITIMPAFIFEHIIKRMAP 278
             + +  MPA +F  +  +  P
Sbjct: 713 GEIHMKTMPAAMFRLLTGQETP 734


>gi|22035550 amyloid beta A4 precursor protein-binding, family A,
           member 2 isoform a [Homo sapiens]
          Length = 749

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)

Query: 140 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 197
           PA+  G L  GDQ++ ING +  G        ++K    + ++ + I   P   T+ + +
Sbjct: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664

Query: 198 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 256
            D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     +I   LS S 
Sbjct: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724

Query: 257 TVVTITIMPAFIFEHIIKRMAP 278
             + +  MPA +F  +  +  P
Sbjct: 725 GEIHMKTMPAAMFRLLTGQETP 746


>gi|11342678 amyloid beta (A4) precursor protein-binding, family A,
           member 3 [Homo sapiens]
          Length = 575

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 44/180 (24%), Positives = 81/180 (45%), Gaps = 8/180 (4%)

Query: 107 REVILCKDQDGKIGLRLKS------IDNGIFVQLVQANSPASLVGLRFGDQVLQINGENC 160
           REV L K +   +G+ L        +   +   L+          L  GD++  ING + 
Sbjct: 393 REVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSL 452

Query: 161 AGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHKD-STGHVGFIFKNGKITSIVKD 218
            G         +++   +  +T++I   P   T  +H+  +   +GF  ++G I S+++ 
Sbjct: 453 VGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRG 512

Query: 219 SSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIKRMAP 278
             A R G+   H I EINGQ+V+    ++I ++L+ +   V I  MPA  +  +  +  P
Sbjct: 513 GIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQP 572


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 11/127 (8%)

Query: 67  VSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSI 126
           VS +   GQ  A P+  + +   V G+D      EI +  R+V+L +   G +G  +   
Sbjct: 431 VSPSSFLGQTPASPARYSPVSKAVLGDD------EITREPRKVVLHRGSTG-LGFNIVGG 483

Query: 127 DNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMT 183
           ++G  IF+  + A  PA L G LR GD+++ +N  +    S ++A   LK A G+ +T+ 
Sbjct: 484 EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNA-GQAVTIV 542

Query: 184 IRDRPFE 190
            + RP E
Sbjct: 543 AQYRPEE 549


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 11/127 (8%)

Query: 67  VSGAPLQGQLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLKSI 126
           VS +   GQ  A P+  + +   V G+D      EI +  R+V+L +   G +G  +   
Sbjct: 431 VSPSSFLGQTPASPARYSPVSKAVLGDD------EITREPRKVVLHRGSTG-LGFNIVGG 483

Query: 127 DNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMT 183
           ++G  IF+  + A  PA L G LR GD+++ +N  +    S ++A   LK A G+ +T+ 
Sbjct: 484 EDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAALKNA-GQAVTIV 542

Query: 184 IRDRPFE 190
            + RP E
Sbjct: 543 AQYRPEE 549


>gi|119943108 synapse-associated protein 102 isoform b [Homo
           sapiens]
          Length = 512

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 107 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 163
           R++IL K   G +G  +   ++G  IFV  + A  PA L G LR GD++L +NG N    
Sbjct: 48  RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 106

Query: 164 SSDKAHKVLKQAFGEKITMTIRDRPFE 190
           + ++A   LK+A G+ +T+  + RP E
Sbjct: 107 THEQAAAALKRA-GQSVTIVAQYRPEE 132



 Score = 28.5 bits (62), Expect = 7.3
 Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 8/78 (10%)

Query: 191 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 243
           R I +HK STG +GF    G+      ++ I+    A  +G L   + I  +NG N+   
Sbjct: 48  RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 106

Query: 244 KDSQIADILSTSGTVVTI 261
              Q A  L  +G  VTI
Sbjct: 107 THEQAAAALKRAGQSVTI 124


>gi|119943106 synapse-associated protein 102 isoform a [Homo
           sapiens]
          Length = 817

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/87 (36%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 107 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 163
           R++IL K   G +G  +   ++G  IFV  + A  PA L G LR GD++L +NG N    
Sbjct: 385 RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 443

Query: 164 SSDKAHKVLKQAFGEKITMTIRDRPFE 190
           + ++A   LK+A G+ +T+  + RP E
Sbjct: 444 THEQAAAALKRA-GQSVTIVAQYRPEE 469



 Score = 28.5 bits (62), Expect = 7.3
 Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 8/78 (10%)

Query: 191 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 243
           R I +HK STG +GF    G+      ++ I+    A  +G L   + I  +NG N+   
Sbjct: 385 RKIILHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNA 443

Query: 244 KDSQIADILSTSGTVVTI 261
              Q A  L  +G  VTI
Sbjct: 444 THEQAAAALKRAGQSVTI 461


>gi|45827729 scribble isoform b [Homo sapiens]
          Length = 1630

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 36/158 (22%), Positives = 67/158 (42%), Gaps = 19/158 (12%)

Query: 129  GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRD-- 186
            G+F+  V     A+  GLR GD++L +NG++    +  +A   L +   E   +  RD  
Sbjct: 1035 GVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVRRDPA 1094

Query: 187  RPFERTITMHKDSTGHVGFIFKNGK----------------ITSIVKDSSAARNG-LLTE 229
             P  R + + K     +G   + G                 I+ +    +A R+G L   
Sbjct: 1095 PPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRDGRLRVG 1154

Query: 230  HNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAF 267
              + E+N Q+++GL   +   +L + G  +T+ +   F
Sbjct: 1155 LRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGF 1192



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 2/75 (2%)

Query: 117 GKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAF 176
           GK     K  D GIF+  V    PA+  G+R GD++L++NG    G    +A + L+ A 
Sbjct: 745 GKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGA- 803

Query: 177 GEKITMTI-RDRPFE 190
           G  + M + R+R  E
Sbjct: 804 GTAVQMRVWRERMVE 818



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)

Query: 117 GKIGLRLKSIDNGIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQA 175
           GK     ++ D GIFV  +     A   G L+ GD+VL ING +      D A  +L  A
Sbjct: 879 GKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAA 938



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 14/87 (16%)

Query: 190 ERTITMHKDSTGHVGFIFKNGK-------------ITSIVKDSSAARNGLLTEHNICEIN 236
           E T+T+ +  TG +G     GK             I+ + ++  AAR G+     + E+N
Sbjct: 726 ELTLTILRQ-TGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVN 784

Query: 237 GQNVIGLKDSQIADILSTSGTVVTITI 263
           G  + G +  +  + L  +GT V + +
Sbjct: 785 GVALQGAEHHEAVEALRGAGTAVQMRV 811


>gi|45827731 scribble isoform a [Homo sapiens]
          Length = 1655

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 36/158 (22%), Positives = 67/158 (42%), Gaps = 19/158 (12%)

Query: 129  GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRD-- 186
            G+F+  V     A+  GLR GD++L +NG++    +  +A   L +   E   +  RD  
Sbjct: 1035 GVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATHQEAVSALLRPCLELSLLVRRDPA 1094

Query: 187  RPFERTITMHKDSTGHVGFIFKNGK----------------ITSIVKDSSAARNG-LLTE 229
             P  R + + K     +G   + G                 I+ +    +A R+G L   
Sbjct: 1095 PPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRDGRLRVG 1154

Query: 230  HNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAF 267
              + E+N Q+++GL   +   +L + G  +T+ +   F
Sbjct: 1155 LRLLEVNQQSLLGLTHGEAVQLLRSVGDTLTVLVCDGF 1192



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 2/75 (2%)

Query: 117 GKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAF 176
           GK     K  D GIF+  V    PA+  G+R GD++L++NG    G    +A + L+ A 
Sbjct: 745 GKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGA- 803

Query: 177 GEKITMTI-RDRPFE 190
           G  + M + R+R  E
Sbjct: 804 GTAVQMRVWRERMVE 818



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)

Query: 117 GKIGLRLKSIDNGIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQA 175
           GK     ++ D GIFV  +     A   G L+ GD+VL ING +      D A  +L  A
Sbjct: 879 GKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAA 938



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 14/87 (16%)

Query: 190 ERTITMHKDSTGHVGFIFKNGK-------------ITSIVKDSSAARNGLLTEHNICEIN 236
           E T+T+ +  TG +G     GK             I+ + ++  AAR G+     + E+N
Sbjct: 726 ELTLTILRQ-TGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVN 784

Query: 237 GQNVIGLKDSQIADILSTSGTVVTITI 263
           G  + G +  +  + L  +GT V + +
Sbjct: 785 GVALQGAEHHEAVEALRGAGTAVQMRV 811


>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
          Length = 749

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 5/85 (5%)

Query: 107 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 163
           R+V+L K   G +G  +   ++G  IFV  + A  PA L G L+ GDQ+L +NG +  G 
Sbjct: 317 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 375

Query: 164 SSDKAHKVLKQAFGEKITMTIRDRP 188
           S ++A   LK A G+ +T+  + +P
Sbjct: 376 SHEQAAAALKGA-GQTVTIIAQYQP 399



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 8/78 (10%)

Query: 191 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 243
           R + +HK STG +GF    G+      ++ I+    A  +G L   + I  +NG ++ G 
Sbjct: 317 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 375

Query: 244 KDSQIADILSTSGTVVTI 261
              Q A  L  +G  VTI
Sbjct: 376 SHEQAAAALKGAGQTVTI 393


>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
          Length = 975

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 5/85 (5%)

Query: 107 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 163
           R+V+L K   G +G  +   ++G  IFV  + A  PA L G L+ GDQ+L +NG +  G 
Sbjct: 525 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 583

Query: 164 SSDKAHKVLKQAFGEKITMTIRDRP 188
           S ++A   LK A G+ +T+  + +P
Sbjct: 584 SHEQAAAALKGA-GQTVTIIAQYQP 607



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 8/78 (10%)

Query: 191 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 243
           R + +HK STG +GF    G+      ++ I+    A  +G L   + I  +NG ++ G 
Sbjct: 525 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 583

Query: 244 KDSQIADILSTSGTVVTI 261
              Q A  L  +G  VTI
Sbjct: 584 SHEQAAAALKGAGQTVTI 601


>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
          Length = 870

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 5/85 (5%)

Query: 107 REVILCKDQDGKIGLRLKSIDNG--IFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 163
           R+V+L K   G +G  +   ++G  IFV  + A  PA L G L+ GDQ+L +NG +  G 
Sbjct: 420 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 478

Query: 164 SSDKAHKVLKQAFGEKITMTIRDRP 188
           S ++A   LK A G+ +T+  + +P
Sbjct: 479 SHEQAAAALKGA-GQTVTIIAQYQP 502



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 8/78 (10%)

Query: 191 RTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVIGL 243
           R + +HK STG +GF    G+      ++ I+    A  +G L   + I  +NG ++ G 
Sbjct: 420 RKVVLHKGSTG-LGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGA 478

Query: 244 KDSQIADILSTSGTVVTI 261
              Q A  L  +G  VTI
Sbjct: 479 SHEQAAAALKGAGQTVTI 496


>gi|11993943 Tax1 binding protein 3 [Homo sapiens]
          Length = 124

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 19/67 (28%), Positives = 37/67 (55%)

Query: 127 DNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRD 186
           D GI+V  V    PA + GL+ GD+++Q+NG +    + D+A K L +   E + + +  
Sbjct: 52  DKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTR 111

Query: 187 RPFERTI 193
           +  ++ +
Sbjct: 112 QSLQKAV 118


>gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo
           sapiens]
          Length = 1544

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 24/90 (26%), Positives = 49/90 (54%), Gaps = 3/90 (3%)

Query: 99  RAEIKQGIREVILCKDQDGKIGLRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGE 158
           R+EI   ++  ++ +  D   GL +   DN +FVQ V+ +  A   G++ GD+++++NG 
Sbjct: 62  RSEIYGLVQRCVIIQKDDNGFGLTVSG-DNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT 120

Query: 159 NCAGWSSDKAHKVLKQAFGEKITMTIRDRP 188
                +  +  K++K   G  + +T++ RP
Sbjct: 121 LVTHSNHLEVVKLIKS--GSYVALTVQGRP 148


>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
           sapiens]
          Length = 767

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%)

Query: 129 GIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDR 187
           GIF+  + A  PA L G LR GDQ+L +NG +    S ++A   LK A G+ +T+  + +
Sbjct: 378 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA-GQTVTIIAQYK 436

Query: 188 PFE 190
           P E
Sbjct: 437 PEE 439


>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
           sapiens]
          Length = 721

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%)

Query: 129 GIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDR 187
           GIF+  + A  PA L G LR GDQ+L +NG +    S ++A   LK A G+ +T+  + +
Sbjct: 332 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA-GQTVTIIAQYK 390

Query: 188 PFE 190
           P E
Sbjct: 391 PEE 393


>gi|21361142 PDZ domain containing 1 [Homo sapiens]
          Length = 519

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 49/206 (23%)

Query: 107 REVILCKDQDGKIG--LRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWS 164
           RE  L K +    G  LR++    G  V++V+  SPA   GL+ GD+VL+ING       
Sbjct: 8   RECKLSKQEGQNYGFFLRIEKDTEGHLVRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEE 67

Query: 165 SDKAHKVLKQAFGEKITMTIRD-RPFERTITMHKD------------------------- 198
             +   +++++ G  +T+ + D   +E+ +    D                         
Sbjct: 68  HMQVVDLVRKS-GNSVTLLVLDGDSYEKAVKTRVDLKELGQSQKEQGLSDNILSPVMNGG 126

Query: 199 --------------STGHVGFIFK--NGK----ITSIVKDSSAARNGLLTEHNICEINGQ 238
                           G  GF  K   GK    +T I     A R G+L + ++ E+NG+
Sbjct: 127 VQTWTQPRLCYLVKEGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGE 186

Query: 239 NVIGLKDSQIADILSTSGTVVTITIM 264
           NV      ++ + +  SG+ V   ++
Sbjct: 187 NVEDASHEEVVEKVKKSGSRVMFLLV 212



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 35/182 (19%), Positives = 73/182 (40%), Gaps = 34/182 (18%)

Query: 115 QDGKIGLRLKSIDN--GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVL 172
           + G  G  LK++    G+++  +     A   G+   D ++++NGEN    S ++  + +
Sbjct: 141 EGGSYGFSLKTVQGKKGVYMTDITPQGVAMRAGVLADDHLIEVNGENVEDASHEEVVEKV 200

Query: 173 KQAFGEKITMTIRDRPFE------------------------RTITMHKDSTGHVGFIFK 208
           K++ G ++   + D+  +                        R + M K S G+ GF  +
Sbjct: 201 KKS-GSRVMFLLVDKETDKRHVEQKIQFKRETASLKLLPHQPRIVEMKKGSNGY-GFYLR 258

Query: 209 NGK------ITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTIT 262
            G       I  I   S A   GL     +  +NG++V  L    + +++   G   ++ 
Sbjct: 259 AGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKGGDQTSLL 318

Query: 263 IM 264
           ++
Sbjct: 319 VV 320



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 45/222 (20%), Positives = 82/222 (36%), Gaps = 58/222 (26%)

Query: 121 LRLKSIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKI 180
           LR  S   G  ++ + + SPA   GL+  D V+ +NGE+      D   +++++  G++ 
Sbjct: 257 LRAGSEQKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESVETLDHDSVVEMIRKG-GDQT 315

Query: 181 TMTIRDR----------------------------------PFERTITMHKDST------ 200
           ++ + D+                                  P    ++   D+T      
Sbjct: 316 SLLVVDKETDNMYRLAHFSPFLYYQSQELPNGSVKEAPAPTPTSLEVSSPPDTTEEVDHK 375

Query: 201 --------GHVGFIFKNGKI--------TSIVKDSSAARNGLLTEHNICEINGQNVIGLK 244
                   G  G+ F    I          + K   A   GL  E  I E+NG NV+   
Sbjct: 376 PKLCRLAKGENGYGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEP 435

Query: 245 DSQIADILSTSGTVVTITIMPAFIFEHIIKRMAPSIMKSLMD 286
             ++ D + +SG  VT+ +     +++   +  P I+ SL D
Sbjct: 436 YEKVVDRIQSSGKNVTLLVCGKKAYDYFQAKKIP-IVSSLAD 476



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 4/76 (5%)

Query: 111 LCKDQDGKIGLRLKSIDN--GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKA 168
           L K ++G  G  L +I    G F++ VQ   PA L GL   D ++++NG N      +K 
Sbjct: 381 LAKGENG-YGFHLNAIRGLPGSFIKEVQKGGPADLAGLEDEDVIIEVNGVNVLDEPYEKV 439

Query: 169 HKVLKQAFGEKITMTI 184
              + Q+ G+ +T+ +
Sbjct: 440 VDRI-QSSGKNVTLLV 454



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 8/82 (9%)

Query: 193 ITMHKDSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADIL 252
           + + KD+ GH+        +  + K S A + GL     +  ING  V   +  Q+ D++
Sbjct: 24  LRIEKDTEGHL--------VRVVEKCSPAEKAGLQDGDRVLRINGVFVDKEEHMQVVDLV 75

Query: 253 STSGTVVTITIMPAFIFEHIIK 274
             SG  VT+ ++    +E  +K
Sbjct: 76  RKSGNSVTLLVLDGDSYEKAVK 97


>gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchange
           factor 2, partial [Homo sapiens]
          Length = 803

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 23/66 (34%), Positives = 36/66 (54%)

Query: 129 GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRP 188
           GIFV  V + S A+  GL+ GDQ+L++NG+N       KA ++L+      IT+      
Sbjct: 410 GIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFV 469

Query: 189 FERTIT 194
           F+  +T
Sbjct: 470 FKELLT 475



 Score = 32.7 bits (73), Expect = 0.39
 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 212 ITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMP-AFIFE 270
           + S+   S A   GL     I E+NGQN   ++ S+  +IL  + T ++IT+    F+F+
Sbjct: 413 VDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEIL-RNNTHLSITVKTNLFVFK 471

Query: 271 HIIKRMA 277
            ++ R++
Sbjct: 472 ELLTRLS 478


>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
          Length = 1332

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 7/89 (7%)

Query: 106 IREVILCKDQDGKIGLRLKSIDN------GIFVQLVQANSPASLVG-LRFGDQVLQINGE 158
           I  ++L K Q   +G  +    +      GI+V+ + A   A+  G L+ GD++L++NGE
Sbjct: 214 ISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILELNGE 273

Query: 159 NCAGWSSDKAHKVLKQAFGEKITMTIRDR 187
           + AG +   A +  KQA    +T+T+R R
Sbjct: 274 SMAGLTHQDALQKFKQAKKGLLTLTVRTR 302



 Score = 32.3 bits (72), Expect = 0.51
 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 7/83 (8%)

Query: 100  AEIKQ--GIREVILCKDQDGKIGLRLKS---IDNGIF-VQLVQANSPASLVG-LRFGDQV 152
            A +KQ  GI   IL K++   +G  L     ++N +  V  V  N  AS  G ++ G++V
Sbjct: 1103 ATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEV 1162

Query: 153  LQINGENCAGWSSDKAHKVLKQA 175
            L ING++  G +   A  +L+QA
Sbjct: 1163 LSINGKSLKGTTHHDALAILRQA 1185


>gi|9507163 syntrophin, gamma 1 [Homo sapiens]
          Length = 517

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 16/107 (14%)

Query: 178 EKITMTIRDRPF---ERTITMHKDSTGHVGFIFKNGK-------ITSIVKDSSAARNGLL 227
           E+  + +   PF   ERT+T+ + + G  G   K G        ++ I K+  A  +GLL
Sbjct: 40  EQDVICVSGEPFYSGERTVTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLL 99

Query: 228 TEHN-ICEINGQNVIGLKDSQIADILSTSGTVVTITI-----MPAFI 268
              + I +ING NV   +  ++  +L  +G  VT+T+      PAF+
Sbjct: 100 FIGDAILQINGINVRKCRHEEVVQVLRNAGEEVTLTVSFLKRAPAFL 146



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 28/84 (33%), Positives = 43/84 (51%), Gaps = 5/84 (5%)

Query: 105 GIREVILCKDQDGKIGLRLKS---IDNGIFVQLVQANSPASLVGLRF-GDQVLQINGENC 160
           G R V + +   G  GL +K     +  + V  +     A L GL F GD +LQING N 
Sbjct: 54  GERTVTIRRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINV 113

Query: 161 AGWSSDKAHKVLKQAFGEKITMTI 184
                ++  +VL+ A GE++T+T+
Sbjct: 114 RKCRHEEVVQVLRNA-GEEVTLTV 136


>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
          Length = 1499

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 23/66 (34%), Positives = 36/66 (54%)

Query: 129 GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRP 188
           GIFV  V + S A+  GL+ GDQ+L++NG+N       KA ++L+      IT+      
Sbjct: 410 GIFVDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEILRNNTHLSITVKTNLFV 469

Query: 189 FERTIT 194
           F+  +T
Sbjct: 470 FKELLT 475



 Score = 32.7 bits (73), Expect = 0.39
 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 2/67 (2%)

Query: 212 ITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMP-AFIFE 270
           + S+   S A   GL     I E+NGQN   ++ S+  +IL  + T ++IT+    F+F+
Sbjct: 413 VDSVDSGSKATEAGLKRGDQILEVNGQNFENIQLSKAMEIL-RNNTHLSITVKTNLFVFK 471

Query: 271 HIIKRMA 277
            ++ R++
Sbjct: 472 ELLTRLS 478


>gi|95089461 discs large homolog 5 [Homo sapiens]
          Length = 1919

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 129  GIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDRP 188
            GI+V  V   S A   GL +GDQ+L+ NG N    +  +A  ++ Q   + IT+  +  P
Sbjct: 1371 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQC-DTITILAQYNP 1429

Query: 189  FERTITMHKDSTGHV 203
                ++ H  S+ H+
Sbjct: 1430 HVHQLSSHSRSSSHL 1444



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 125 SIDNGIFVQLVQANSPASLVG-LRFGDQVLQING 157
           S++NG++   V   SPA+  G L  GD+++ ING
Sbjct: 733 SLENGVYAAAVLPGSPAAKEGSLAVGDRIVAING 766


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,127,793
Number of Sequences: 37866
Number of extensions: 420819
Number of successful extensions: 1324
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 1071
Number of HSP's gapped (non-prelim): 312
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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