Search of human proteins with 53988383

Search of human proteins with 53988383

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53988383 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A4 [Homo sapiens]
         (140 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32698882 family with sequence similarity 19 (chemokine (C-C m...   304   2e-83
gi|53988383 family with sequence similarity 19 (chemokine (C-C m...   304   2e-83
gi|30425496 family with sequence similarity 19 (chemokine (C-C m...   190   4e-49
gi|33300649 family with sequence similarity 19 (chemokine (C-C m...   179   7e-46
gi|50962799 family with sequence similarity 19 (chemokine (C-C m...   172   1e-43
gi|53933210 family with sequence similarity 19 (chemokine (C-C m...   102   8e-23
gi|131887988 family with sequence similarity 19 (chemokine (C-C ...   101   2e-22
gi|52486734 family with sequence similarity 19 (chemokine (C-C m...    95   2e-20
gi|56237021 fibrillin 3 precursor [Homo sapiens]                       32   0.17 
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    32   0.17 
gi|54873613 agrin [Homo sapiens]                                       32   0.22 
gi|40317628 thrombospondin 2 precursor [Homo sapiens]                  31   0.38 
gi|6005902 thrombospondin 3 precursor [Homo sapiens]                   31   0.38 
gi|24308352 DMRT-like family B with proline-rich C-terminal, 1 [...    30   0.49 
gi|4557733 latent transforming growth factor beta binding protei...    30   0.84 
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]            30   0.84 
gi|40317626 thrombospondin 1 precursor [Homo sapiens]                  29   1.1  
gi|112420992 crumbs homolog 2 [Homo sapiens]                           29   1.4  
gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]           28   1.9  
gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]           28   1.9  
gi|21704279 jagged 2 isoform b precursor [Homo sapiens]                28   1.9  
gi|21704277 jagged 2 isoform a precursor [Homo sapiens]                28   1.9  
gi|148833508 notch1 preproprotein [Homo sapiens]                       28   2.5  
gi|41327708 crumbs homolog 1 precursor [Homo sapiens]                  28   2.5  
gi|110347437 latent transforming growth factor beta binding prot...    28   2.5  
gi|110347412 latent transforming growth factor beta binding prot...    28   2.5  
gi|110347431 latent transforming growth factor beta binding prot...    28   2.5  
gi|134244285 Notch homolog 3 [Homo sapiens]                            28   3.2  
gi|93102379 low density lipoprotein-related protein 1B precursor...    27   4.2  
gi|55770876 notch4 preproprotein [Homo sapiens]                        27   4.2  

>gi|32698882 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A4 [Homo sapiens]
          Length = 140

 Score =  304 bits (778), Expect = 2e-83
 Identities = 140/140 (100%), Positives = 140/140 (100%)

Query: 1   MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHR 60
           MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHR
Sbjct: 1   MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHR 60

Query: 61  CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP 120
           CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP
Sbjct: 61  CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP 120

Query: 121 DYSGWSCSSGNKVKTTKVTR 140
           DYSGWSCSSGNKVKTTKVTR
Sbjct: 121 DYSGWSCSSGNKVKTTKVTR 140


>gi|53988383 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A4 [Homo sapiens]
          Length = 140

 Score =  304 bits (778), Expect = 2e-83
 Identities = 140/140 (100%), Positives = 140/140 (100%)

Query: 1   MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHR 60
           MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHR
Sbjct: 1   MRSPRMRVCAKSVLLSHWLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHR 60

Query: 61  CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP 120
           CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP
Sbjct: 61  CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP 120

Query: 121 DYSGWSCSSGNKVKTTKVTR 140
           DYSGWSCSSGNKVKTTKVTR
Sbjct: 121 DYSGWSCSSGNKVKTTKVTR 140


>gi|30425496 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A2 [Homo sapiens]
          Length = 131

 Score =  190 bits (482), Expect = 4e-49
 Identities = 85/121 (70%), Positives = 101/121 (83%), Gaps = 5/121 (4%)

Query: 19  LFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSC 78
           L + +++ +  K++S+++ H       H +K GTCEVVA+HRCCNKN+IEERSQTVKCSC
Sbjct: 15  LIIIFIVTLWGKVVSSANHHKA-----HHVKTGTCEVVALHRCCNKNKIEERSQTVKCSC 69

Query: 79  FPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTKV 138
           FPGQVAGTTRA PSCV+ASIV QKWWCHM PCLEGE+CKVLPD  GWSCSSGNKVKTT+V
Sbjct: 70  FPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRV 129

Query: 139 T 139
           T
Sbjct: 130 T 130


>gi|33300649 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A3 isoform 1 [Homo sapiens]
          Length = 133

 Score =  179 bits (454), Expect = 7e-46
 Identities = 77/93 (82%), Positives = 87/93 (93%)

Query: 48  IKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHM 107
           ++QGTCEV+A HRCCN+NRIEERSQTVKCSCF GQVAGTTRA+PSCV+ASIV+Q+WWC M
Sbjct: 41  VQQGTCEVIAAHRCCNRNRIEERSQTVKCSCFSGQVAGTTRAKPSCVDASIVLQRWWCQM 100

Query: 108 NPCLEGEDCKVLPDYSGWSCSSGNKVKTTKVTR 140
            PCL GE+CKVLPD SGWSCSSG+KVKTTKVTR
Sbjct: 101 EPCLPGEECKVLPDLSGWSCSSGHKVKTTKVTR 133


>gi|50962799 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A1 [Homo sapiens]
          Length = 133

 Score =  172 bits (435), Expect = 1e-43
 Identities = 75/121 (61%), Positives = 90/121 (74%)

Query: 18  WLFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCS 77
           W+   ++      L   S QH       H+ + GTCEV+A HRCCNKNRIEERSQTVKCS
Sbjct: 9   WVLYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCS 68

Query: 78  CFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTK 137
           C PG+VAGTTR +PSCV+ASIVI KWWC M PCLEGE+CK LPD SGW C++GNK+KTT+
Sbjct: 69  CLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTR 128

Query: 138 V 138
           +
Sbjct: 129 I 129


>gi|53933210 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A5 isoform 2 [Homo sapiens]
          Length = 125

 Score =  102 bits (255), Expect = 8e-23
 Identities = 51/120 (42%), Positives = 75/120 (62%), Gaps = 5/120 (4%)

Query: 21  LAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFP 80
           LA   + C  ++   +Q L+      Q+  GTCE+V + R  ++ R     QT +C+C  
Sbjct: 10  LAGAALCCFLVLVIHAQFLK----EGQLAAGTCEIVTLDRDSSQPRRTIARQTARCACRK 65

Query: 81  GQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSS-GNKVKTTKVT 139
           GQ+AGTTRA+P+CV+A I+  K WC M PCLEGE C +L + SGW+C+  G ++KTT V+
Sbjct: 66  GQIAGTTRARPACVDARIIKTKQWCDMLPCLEGEGCDLLINRSGWTCTQPGGRIKTTTVS 125


>gi|131887988 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A5 isoform 1 [Homo sapiens]
          Length = 132

 Score =  101 bits (252), Expect = 2e-22
 Identities = 46/94 (48%), Positives = 65/94 (69%), Gaps = 1/94 (1%)

Query: 47  QIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCH 106
           Q+  GTCE+V + R  ++ R     QT +C+C  GQ+AGTTRA+P+CV+A I+  K WC 
Sbjct: 39  QLAAGTCEIVTLDRDSSQPRRTIARQTARCACRKGQIAGTTRARPACVDARIIKTKQWCD 98

Query: 107 MNPCLEGEDCKVLPDYSGWSCSS-GNKVKTTKVT 139
           M PCLEGE C +L + SGW+C+  G ++KTT V+
Sbjct: 99  MLPCLEGEGCDLLINRSGWTCTQPGGRIKTTTVS 132


>gi|52486734 family with sequence similarity 19 (chemokine (C-C
          motif)-like), member A3 isoform 2 [Homo sapiens]
          Length = 169

 Score = 95.1 bits (235), Expect = 2e-20
 Identities = 40/48 (83%), Positives = 46/48 (95%)

Query: 48 IKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVE 95
          ++QGTCEV+A HRCCN+NRIEERSQTVKCSCF GQVAGTTRA+PSCV+
Sbjct: 41 VQQGTCEVIAAHRCCNRNRIEERSQTVKCSCFSGQVAGTTRAKPSCVD 88


>gi|56237021 fibrillin 3 precursor [Homo sapiens]
          Length = 2809

 Score = 32.0 bits (71), Expect = 0.17
 Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 9/89 (10%)

Query: 31  LMSASSQHLRGHAGHHQIKQGTCEVVAVHRC----CNKNRIEERSQTVKCSCFPGQVAGT 86
           L + SS     + G+ Q  +G C  + V  C    C+         T  C C+PG  A  
Sbjct: 425 LPTPSSYRCECNVGYTQDVRGEC--IDVDECTSSPCHHGDCVNIPGTYHCRCYPGFQATP 482

Query: 87  TRAQPSCVEA-SIVIQKWWCHMNPCLEGE 114
           TR   +CV+    ++    CH+  C+  E
Sbjct: 483 TR--QACVDVDECIVSGGLCHLGRCVNTE 509


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 32.0 bits (71), Expect = 0.17
 Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 15/57 (26%)

Query: 72   QTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDY-SGWSC 127
            QT  C+C PG         P CV+A        C +NPC     C+ LP    G++C
Sbjct: 1966 QTFSCTCQPGYYG------PGCVDA--------CLLNPCQNQGSCRHLPGAPHGYTC 2008


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 31.6 bits (70), Expect = 0.22
 Identities = 28/116 (24%), Positives = 40/116 (34%), Gaps = 32/116 (27%)

Query: 20   FLAYVLMVCCKLMSASSQHLR--------------GHAGHHQIKQGTCEVVAVHRCCNKN 65
            F+   L  C +L+  ++Q L               G  G H      C   A  +     
Sbjct: 1511 FVGAGLRGCIRLLDVNNQRLELGIGPGAATRGSGVGECGDHPCLPNPCHGGAPCQNLEAG 1570

Query: 66   RIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPD 121
            R         C C PG+V       P+C +     +K  C  NPC     C+VLP+
Sbjct: 1571 RFH-------CQCPPGRVG------PTCAD-----EKSPCQPNPCHGAAPCRVLPE 1608


>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
          Length = 1172

 Score = 30.8 bits (68), Expect = 0.38
 Identities = 13/25 (52%), Positives = 13/25 (52%), Gaps = 1/25 (4%)

Query: 105 CHMNPCLEGEDCKVLPDYSGWSCSS 129
           C  NPC  G  C   PD S WSC S
Sbjct: 553 CLSNPCFPGAQCSSFPDGS-WSCGS 576


>gi|6005902 thrombospondin 3 precursor [Homo sapiens]
          Length = 956

 Score = 30.8 bits (68), Expect = 0.38
 Identities = 11/27 (40%), Positives = 15/27 (55%)

Query: 101 QKWWCHMNPCLEGEDCKVLPDYSGWSC 127
           Q+  C  NPC  G DC  + +Y G+ C
Sbjct: 274 QRSHCSPNPCFRGVDCMEVYEYPGYRC 300


>gi|24308352 DMRT-like family B with proline-rich C-terminal, 1
          [Homo sapiens]
          Length = 342

 Score = 30.4 bits (67), Expect = 0.49
 Identities = 18/66 (27%), Positives = 28/66 (42%), Gaps = 10/66 (15%)

Query: 39 LRGHAGHHQIKQGTCE----------VVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTR 88
          ++GHAG  + KQ  CE          ++A  +       EE  +   C+  P Q +G   
Sbjct: 23 VKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQEAALCAQGPKQASGAAA 82

Query: 89 AQPSCV 94
          A P+ V
Sbjct: 83 AAPAPV 88


>gi|4557733 latent transforming growth factor beta binding protein 2
           [Homo sapiens]
          Length = 1821

 Score = 29.6 bits (65), Expect = 0.84
 Identities = 15/54 (27%), Positives = 20/54 (37%)

Query: 61  CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGE 114
           C  K R   R  +  C C+PG    T+ A   C + +   Q   C    C   E
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTE 949


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score = 29.6 bits (65), Expect = 0.84
 Identities = 23/90 (25%), Positives = 31/90 (34%), Gaps = 24/90 (26%)

Query: 44  GHHQIKQGTC--------EVVAVHRCCNKNRIEERSQTVKCSCFPGQVA---------GT 86
           G  + + G C        E   V  C    R   R ++ +C C+PG            G 
Sbjct: 441 GRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGD 500

Query: 87  TRAQPSCVEASIVIQKWWCHMNPCLEGEDC 116
            R +  CV+         C  NP   GEDC
Sbjct: 501 CRGRGRCVDGR-------CVCNPGFTGEDC 523


>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
          Length = 1170

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 16/40 (40%), Positives = 18/40 (45%), Gaps = 7/40 (17%)

Query: 105 CHMNPCLEGEDCKVLPDYSGWSCS------SGNKVKTTKV 138
           C  NPC  G  C   PD S W C       SGN ++ T V
Sbjct: 551 CLSNPCFAGVKCTSYPDGS-WKCGACPPGYSGNGIQCTDV 589


>gi|112420992 crumbs homolog 2 [Homo sapiens]
          Length = 1285

 Score = 28.9 bits (63), Expect = 1.4
 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 11/69 (15%)

Query: 61   CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP 120
            C + +  E  S    CSC  G +AG     P+            C  NPCL G  C+   
Sbjct: 1144 CLDGSPCEGGSPAANCSCLEG-LAGQRCQVPTLP----------CEANPCLNGGTCRAAG 1192

Query: 121  DYSGWSCSS 129
              S   C++
Sbjct: 1193 GVSECICNA 1201



 Score = 27.7 bits (60), Expect = 3.2
 Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 14/52 (26%)

Query: 76  CSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSC 127
           C+C P    G     P+C       Q+ WC   PCL    C+ +PD  G+ C
Sbjct: 831 CTC-PANFTG-----PTCA------QQLWCPGQPCLPPATCEEVPD--GFVC 868


>gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]
          Length = 195

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 9/21 (42%), Positives = 12/21 (57%)

Query: 110 CLEGEDCKVLPDYSGWSCSSG 130
           C+ G  C  LP + GW+C  G
Sbjct: 108 CMLGSFCACLPSFYGWNCEHG 128


>gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]
          Length = 195

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 9/21 (42%), Positives = 12/21 (57%)

Query: 110 CLEGEDCKVLPDYSGWSCSSG 130
           C+ G  C  LP + GW+C  G
Sbjct: 108 CMLGSFCACLPSFYGWNCEHG 128


>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
          Length = 1200

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/89 (24%), Positives = 31/89 (34%), Gaps = 17/89 (19%)

Query: 59  HRCCNKNRIEERSQTVKCSCFPG------QVAGTTRAQPS-CVEASIVIQKWWCHMNPCL 111
           + C N     +   T +C+C PG       VA  +   P+ CV     +         C 
Sbjct: 681 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICR 740

Query: 112 EG----------EDCKVLPDYSGWSCSSG 130
           +G           DC  LP Y+G  C  G
Sbjct: 741 DGWEGRTCTHNTNDCNPLPCYNGGICVDG 769


>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
          Length = 1238

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 22/89 (24%), Positives = 31/89 (34%), Gaps = 17/89 (19%)

Query: 59  HRCCNKNRIEERSQTVKCSCFPG------QVAGTTRAQPS-CVEASIVIQKWWCHMNPCL 111
           + C N     +   T +C+C PG       VA  +   P+ CV     +         C 
Sbjct: 719 YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICR 778

Query: 112 EG----------EDCKVLPDYSGWSCSSG 130
           +G           DC  LP Y+G  C  G
Sbjct: 779 DGWEGRTCTHNTNDCNPLPCYNGGICVDG 807


>gi|148833508 notch1 preproprotein [Homo sapiens]
          Length = 2555

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 17/71 (23%), Positives = 27/71 (38%), Gaps = 11/71 (15%)

Query: 57  AVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDC 116
           A + C N+    +     KC+C       T           +V+    C  +PC  G +C
Sbjct: 796 ASNPCLNQGTCIDDVAGYKCNCLLPYTGAT---------CEVVLAP--CAPSPCRNGGEC 844

Query: 117 KVLPDYSGWSC 127
           +   DY  +SC
Sbjct: 845 RQSEDYESFSC 855



 Score = 26.6 bits (57), Expect = 7.1
 Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 13/54 (24%)

Query: 75  KCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCS 128
           KC C PG  +GT          +  I    C  NPC+ G  CK +   SG+ C+
Sbjct: 738 KCDCDPGW-SGT----------NCDINNNECESNPCVNGGTCKDMT--SGYVCT 778


>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
          Length = 1406

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 23/88 (26%), Positives = 30/88 (34%), Gaps = 22/88 (25%)

Query: 40  RGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIV 99
           +G AG +  K   C         N      R     CSC P   +G      +C E    
Sbjct: 883 QGCAGDNSCKSNPCH--------NGGVCHSRWDDFSCSC-PALTSGK-----ACEEVQ-- 926

Query: 100 IQKWWCHMNPCLEGEDCKVLPDYSGWSC 127
               WC  +PC  G  C+  P   G+ C
Sbjct: 927 ----WCGFSPCPHGAQCQ--PVLQGFEC 948



 Score = 28.1 bits (61), Expect = 2.5
 Identities = 11/24 (45%), Positives = 16/24 (66%), Gaps = 2/24 (8%)

Query: 105  CHMNPCLEGEDCKVLPDYSGWSCS 128
            C+ NPCL G +C+ +  YS + CS
Sbjct: 1143 CNSNPCLHGGNCEDI--YSSYHCS 1164


>gi|110347437 latent transforming growth factor beta binding protein
           4 isoform c [Homo sapiens]
          Length = 1557

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 18/79 (22%)

Query: 43  AGHHQIKQGTCEVV-----AVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEAS 97
           +GHH + +G C  V         C           + +CSC PG  A + R  P C +  
Sbjct: 756 SGHH-LHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD-- 811

Query: 98  IVIQKWWCHMNPCLEGEDC 116
                    +N CLEG+ C
Sbjct: 812 ---------VNECLEGDFC 821


>gi|110347412 latent transforming growth factor beta binding protein
           4 isoform b [Homo sapiens]
          Length = 1587

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 18/79 (22%)

Query: 43  AGHHQIKQGTCEVV-----AVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEAS 97
           +GHH + +G C  V         C           + +CSC PG  A + R  P C +  
Sbjct: 786 SGHH-LHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD-- 841

Query: 98  IVIQKWWCHMNPCLEGEDC 116
                    +N CLEG+ C
Sbjct: 842 ---------VNECLEGDFC 851


>gi|110347431 latent transforming growth factor beta binding protein
           4 isoform a [Homo sapiens]
          Length = 1624

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 18/79 (22%)

Query: 43  AGHHQIKQGTCEVV-----AVHRCCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEAS 97
           +GHH + +G C  V         C           + +CSC PG  A + R  P C +  
Sbjct: 823 SGHH-LHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD-- 878

Query: 98  IVIQKWWCHMNPCLEGEDC 116
                    +N CLEG+ C
Sbjct: 879 ---------VNECLEGDFC 888


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 27.7 bits (60), Expect = 3.2
 Identities = 19/69 (27%), Positives = 24/69 (34%), Gaps = 11/69 (15%)

Query: 62  CNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPD 121
           C+  R  +   +  C+C PG     TR +    E         C   PC  G  C  L D
Sbjct: 554 CHHGRCVDGIASFSCACAPGYTG--TRCESQVDE---------CRSQPCRHGGKCLDLVD 602

Query: 122 YSGWSCSSG 130
                C SG
Sbjct: 603 KYLCRCPSG 611


>gi|93102379 low density lipoprotein-related protein 1B precursor
            [Homo sapiens]
          Length = 4599

 Score = 27.3 bits (59), Expect = 4.2
 Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 4/33 (12%)

Query: 52   TCEVV---AVHRCCNKNRIEERSQTVKCSCFPG 81
            TCE+V   + H  C++   E+   TVKCSC+ G
Sbjct: 1211 TCEIVDYCSNHLKCSQV-CEQHKHTVKCSCYEG 1242


>gi|55770876 notch4 preproprotein [Homo sapiens]
          Length = 2003

 Score = 27.3 bits (59), Expect = 4.2
 Identities = 16/53 (30%), Positives = 20/53 (37%), Gaps = 13/53 (24%)

Query: 76  CSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCS 128
           C+C  G         P+C E         CH  PCL G  C   P   G+ C+
Sbjct: 715 CTCPTGYTG------PTCSEEMTA-----CHSGPCLNGGSCN--PSPGGYYCT 754



 Score = 26.9 bits (58), Expect = 5.5
 Identities = 19/70 (27%), Positives = 24/70 (34%), Gaps = 11/70 (15%)

Query: 61  CCNKNRIEERSQTVKCSCFPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLP 120
           C N  + +++     C C PG      R Q    E         C  +PC  G  C  LP
Sbjct: 560 CANGGQCQDQPGAFHCKCLPGFEG--PRCQTEVDE---------CLSDPCPVGASCLDLP 608

Query: 121 DYSGWSCSSG 130
                 C SG
Sbjct: 609 GAFFCLCPSG 618


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.131    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,601,661
Number of Sequences: 37866
Number of extensions: 224917
Number of successful extensions: 925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 869
Number of HSP's gapped (non-prelim): 91
length of query: 140
length of database: 18,247,518
effective HSP length: 92
effective length of query: 48
effective length of database: 14,763,846
effective search space: 708664608
effective search space used: 708664608
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.