Guide to the Human Genome
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Search of human proteins with 5031561

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031561 transmembrane glycoprotein A33 precursor [Homo
sapiens]
         (319 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]    650   0.0  
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho...   137   2e-32
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom...   128   8e-30
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s...   124   1e-28
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom...   123   2e-28
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s...   117   1e-26
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]       114   1e-25
gi|148664205 endothelial cell adhesion molecule [Homo sapiens]        106   2e-23
gi|8393638 F11 receptor precursor [Homo sapiens]                       97   2e-20
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s...    89   5e-18
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]    85   7e-17
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]    80   2e-15
gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]          67   2e-11
gi|67188443 CD276 antigen isoform a [Homo sapiens]                     65   1e-10
gi|13376852 CD276 antigen isoform b [Homo sapiens]                     62   5e-10
gi|6005958 V-set and immunoglobulin domain containing 4 isoform ...    62   7e-10
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...    58   1e-08
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         58   1e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    58   1e-08
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ...    58   1e-08
gi|221316762 neurotrimin isoform 4 [Homo sapiens]                      57   2e-08
gi|221316757 neurotrimin isoform 3 [Homo sapiens]                      57   2e-08
gi|115298665 neurotrimin isoform 2 [Homo sapiens]                      57   2e-08
gi|7705413 neurotrimin isoform 1 [Homo sapiens]                        57   2e-08
gi|66346706 neuronal growth regulator 1 [Homo sapiens]                 56   4e-08
gi|222136611 poliovirus receptor-related 4 [Homo sapiens]              56   5e-08
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42...    55   6e-08
gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]               55   8e-08
gi|98986445 carcinoembryonic antigen-related cell adhesion molec...    54   1e-07
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...    54   1e-07

>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score =  650 bits (1678), Expect = 0.0
 Identities = 319/319 (100%), Positives = 319/319 (100%)

Query: 1   MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDK 60
           MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDK
Sbjct: 1   MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDK 60

Query: 61  LLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS 120
           LLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS
Sbjct: 61  LLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS 120

Query: 121 LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI 180
           LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI
Sbjct: 121 LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI 180

Query: 181 LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVG 240
           LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVG
Sbjct: 181 LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVG 240

Query: 241 IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD 300
           IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD
Sbjct: 241 IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD 300

Query: 301 YRQEEQRSTGRESPDHLDQ 319
           YRQEEQRSTGRESPDHLDQ
Sbjct: 301 YRQEEQRSTGRESPDHLDQ 319


>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
           sapiens]
          Length = 365

 Score =  137 bits (344), Expect = 2e-32
 Identities = 95/319 (29%), Positives = 161/319 (50%), Gaps = 29/319 (9%)

Query: 12  LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQWDKLLLT-----H 65
           LC V     ++S+ TP++++  ++G++  LPC +  S   +  L I+W   L++      
Sbjct: 10  LCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEW---LISPADNQK 66

Query: 66  TERVVIWPFSNKNYIHGELY---KNRVSI-SNNAEQSDASITIDQLTMADNGTYECSVSL 121
            ++V+I    +K  I+ + Y   K RV   SN+ +  DASI +  L ++D GTY+C V  
Sbjct: 67  VDQVIILYSGDK--IYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVK- 123

Query: 122 MSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNIL 181
                G    ++ L+VLV PS   C ++G   IG++ ++ C+ KEGS   QY W++ +  
Sbjct: 124 --KAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD- 180

Query: 182 NQEQPLAQPA--SGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYV 239
           +Q+ P +  A  +   +S+KN S++ SG Y CT  N  G+  C + + V  PS    L  
Sbjct: 181 SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIA 240

Query: 240 GIAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEED 299
           G  +G + AL +IG+II+CC    +    E+K +   + +  E+ P      S  R    
Sbjct: 241 GAIIGTLLALALIGLIIFCC----RKKRREEKYEKEVHHDIREDVPPPKSRTSTAR---- 292

Query: 300 DYRQEEQRSTGRESPDHLD 318
            Y      S G  SP +++
Sbjct: 293 SYIGSNHSSLGSMSPSNME 311


>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
           sapiens]
          Length = 430

 Score =  128 bits (321), Expect = 8e-30
 Identities = 88/285 (30%), Positives = 141/285 (49%), Gaps = 9/285 (3%)

Query: 8   VLWTLCAVRVTVDA-ISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHT 66
           +LW  C  R  V A + V      ++ ++G+   LPCT+ TS +     + W    L++ 
Sbjct: 7   LLWWNCFSRTGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNA 66

Query: 67  ---ERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMS 123
              E+V+++    + +     +  RV  +     ++ SI I+   ++D GTY+C V+ + 
Sbjct: 67  NQPEQVILYQ-GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLP 125

Query: 124 DLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY-NILN 182
           D+ G       L VLVPPS P C I+G   IG+++ L C S+EG P P Y W++  N L 
Sbjct: 126 DIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLK 185

Query: 183 QEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPS-MNVALYVGI 241
                 Q      V+++NIS  +SG Y C +SN  GT  C + + V SP   N+ L  G 
Sbjct: 186 LPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAG- 244

Query: 242 AVGVVAALIIIGI-IIYCCCCRGKDDNTEDKEDARPNREAYEEPP 285
           A+G  A +II  I +I       +  N E++E+  PN    ++ P
Sbjct: 245 AIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLP 289


>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
           sapiens]
          Length = 387

 Score =  124 bits (310), Expect = 1e-28
 Identities = 97/340 (28%), Positives = 156/340 (45%), Gaps = 34/340 (10%)

Query: 1   MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQWD 59
           MV   W V   L  +   V  + V  P   +  + G +VTL C Y T+ +SRE L IQW 
Sbjct: 1   MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWS 60

Query: 60  KLLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSV 119
                  E + I+       +    +K+R++ SN  +  +ASITI  +  AD+G Y C V
Sbjct: 61  FFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSN--DPGNASITISHMQPADSGIYICDV 118

Query: 120 SLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY- 178
           +   D  G  +  + + VLV PSKP C ++G    G+ I L+C S  G+P+P Y W +  
Sbjct: 119 NNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLE 178

Query: 179 --NILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVA 236
             +I+  ++    P +G  V + N++    GYY CT+ N  G   C I +    P   V 
Sbjct: 179 GRDIVPVKENF-NPTTGILV-IGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP--EVG 234

Query: 237 LYVGIAVG-VVAALIIIGIIIYC---CCCRGKDDNTE--------------DKEDARPNR 278
           + VG  +G +V A III ++ +       + K+ N++               + +A P  
Sbjct: 235 IIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPRE 294

Query: 279 EAYE---EPPEQLRELSREREEEDDYRQEEQRSTGRESPD 315
           +A +     P  + E   +  +E DY   E + T   +P+
Sbjct: 295 DATQLEVTLPSSIHETGPDTIQEPDY---EPKPTQEPAPE 331


>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
           sapiens]
          Length = 431

 Score =  123 bits (309), Expect = 2e-28
 Identities = 82/271 (30%), Positives = 135/271 (49%), Gaps = 8/271 (2%)

Query: 21  AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHT---ERVVIWPFSNK 77
           ++ V      ++ ++G+   LPCT+ TS +     + W    L++    E+V+++    +
Sbjct: 22  SLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQ-GGQ 80

Query: 78  NYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLV 137
            +     +  RV  +     ++ SI I+   ++D GTY+C V+ + D+ G       L V
Sbjct: 81  MFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTV 140

Query: 138 LVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY-NILNQEQPLAQPASGQPV 196
           LVPPS P C I+G   IG+++ L C S+EG P P Y W++  N L       Q      V
Sbjct: 141 LVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTV 200

Query: 197 SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPS-MNVALYVGIAVGVVAALIIIGI- 254
           +++NIS  +SG Y C +SN  GT  C + + V SP   N+ L  G A+G  A +II  I 
Sbjct: 201 TIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAG-AIGTGAVIIIFCIA 259

Query: 255 IIYCCCCRGKDDNTEDKEDARPNREAYEEPP 285
           +I       +  N E++E+  PN    ++ P
Sbjct: 260 LILGAFFYWRSKNKEEEEEEIPNEIREDDLP 290


>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
           sapiens]
          Length = 327

 Score =  117 bits (294), Expect = 1e-26
 Identities = 78/258 (30%), Positives = 121/258 (46%), Gaps = 10/258 (3%)

Query: 21  AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTH--TERVVIWPFSNKN 78
           A+ V+ P + L    GK+  L CTY TS      L +W  +      +E   I  F+N +
Sbjct: 23  AVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFAL-EWSFVQPGKPISESHPILYFTNGH 81

Query: 79  YIHGELYKNRVSISNNAEQSD-ASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLV 137
                    RVS+  N      A++ +  +  +D GTY C V+   D   N    + L V
Sbjct: 82  LYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTV 141

Query: 138 LVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP---LAQPASGQ 194
           LVPPS P C   G+T +G +  L C S EG+P P Y+W R        P   +    SGQ
Sbjct: 142 LVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ 201

Query: 195 PVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGI 254
            + L N+S  +SG Y C ++N+ G+  C +T++V  PS       G  +GV+  ++++ +
Sbjct: 202 LI-LTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ--GRVAGALIGVLLGVLLLSV 258

Query: 255 IIYCCCCRGKDDNTEDKE 272
             +C     K+   + KE
Sbjct: 259 AAFCLVRFQKERGKKPKE 276


>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
          Length = 373

 Score =  114 bits (285), Expect = 1e-25
 Identities = 85/274 (31%), Positives = 135/274 (49%), Gaps = 19/274 (6%)

Query: 26  TPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQWDKLLLTHTE--RVVIWPFSNKNYIHG 82
           T  ++ R ++ K VTLPC +      ++ L I+W   LLT  E  + V+  +S+++  + 
Sbjct: 19  THTEIKRVAEEK-VTLPCHHQLGLPEKDTLDIEW---LLTDNEGNQKVVITYSSRHVYNN 74

Query: 83  --ELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVP 140
             E  K RV+ ++N    DAS+ I+ L  +D G Y C V           S V L VLV 
Sbjct: 75  LTEEQKGRVAFASNFLAGDASLQIEPLKPSDEGRYTCKVKNSGRY---VWSHVILKVLVR 131

Query: 141 PSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS----GQP- 195
           PSKP+C +EGE   G+++ L C+S  G+    Y W+R      E     P S      P 
Sbjct: 132 PSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYNHPG 191

Query: 196 -VSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGI 254
            V L+N++   SG Y CT+ NE G + C + V V+    ++ +  G   G+VA  ++I +
Sbjct: 192 RVLLQNLTMSYSGLYQCTAGNEAGKESCVVRVTVQY-VQSIGMVAGAVTGIVAGALLIFL 250

Query: 255 IIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQL 288
           +++    R   +  E++E     RE  E P  +L
Sbjct: 251 LVWLLIRRKDKERYEEEERPNEIREDAEAPKARL 284


>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
          Length = 390

 Score =  106 bits (265), Expect = 2e-23
 Identities = 84/273 (30%), Positives = 129/273 (47%), Gaps = 34/273 (12%)

Query: 22  ISVETPQDVLRASQGKSVTLPCTY--HTSTSSREGLIQWDKLLLTHTERVVIWPFSNK-- 77
           + +  P + L+A +G  V LP  Y  H   SS +    W+          V+W F  K  
Sbjct: 31  LQLHLPANRLQAVEGGEVVLPAWYTLHGEVSSSQ---PWEVPF-------VMWFFKQKEK 80

Query: 78  -----NYIHG-ELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKS 131
                +YI+G    K  VS+  +    + S+ ++ L   D+G Y CSV++  D +G ++ 
Sbjct: 81  EDQVLSYINGVTTSKPGVSLVYSMPSRNLSLRLEGLQEKDSGPYSCSVNVQ-DKQGKSRG 139

Query: 132 R----VRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPL 187
                + L VLVPP+ P C ++G   +G N+ L+CQS    P  QY W R   L   Q  
Sbjct: 140 HSIKTLELNVLVPPAPPSCRLQGVPHVGANVTLSCQSPRSKPAVQYQWDRQ--LPSFQTF 197

Query: 188 AQPASG---QPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVG 244
             PA       +SL N+S+  +G Y+C + NE GT  CN+T+ V S     A+  G  VG
Sbjct: 198 FAPALDVIRGSLSLTNLSSSMAGVYVCKAHNEVGTAQCNVTLEV-STGPGAAVVAGAVVG 256

Query: 245 VVAALIIIGIIIYCCCCRGK---DDNTEDKEDA 274
            +  L ++  ++     RGK   +   + KEDA
Sbjct: 257 TLVGLGLLAGLVLLYHRRGKALEEPANDIKEDA 289


>gi|8393638 F11 receptor precursor [Homo sapiens]
          Length = 299

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 79/291 (27%), Positives = 126/291 (43%), Gaps = 46/291 (15%)

Query: 12  LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVI 71
           LC++   + +++V + +  +R  +   V L C Y   +S R                 V 
Sbjct: 21  LCSL--ALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPR-----------------VE 61

Query: 72  WPFSNKNYIHGELYKNRVSISNNAEQS--DASITIDQLTMADNGTYECSVSLMSDLEGNT 129
           W F   +      Y N+++ S     +     IT   +T  D GTY C VS   +  GN+
Sbjct: 62  WKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVS---EEGGNS 118

Query: 130 --KSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP- 186
             + +V+L+VLVPPSKP   I     IGN   LTC  ++GSP  +Y+W +  I+    P 
Sbjct: 119 YGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPK 178

Query: 187 ----------LAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVA 236
                     +  P +G+ V    +S   +G Y C + N  GT   +  V + +   NV 
Sbjct: 179 STRAFSNSSYVLNPTTGELV-FDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVG 237

Query: 237 LYVGIAVGVVAALIIIGII---IYCCCCRGKDDNTEDKEDARPNREAYEEP 284
           +   I   V+  LI++GI+   I+    RG  D T  K+     +  Y +P
Sbjct: 238 V---IVAAVLVTLILLGILVFGIWFAYSRGHFDRT--KKGTSSKKVIYSQP 283


>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
           sapiens]
          Length = 414

 Score = 89.0 bits (219), Expect = 5e-18
 Identities = 81/286 (28%), Positives = 122/286 (42%), Gaps = 45/286 (15%)

Query: 12  LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSR--EGL-IQWDKLLL--THT 66
           L AVR+  D       Q+VL  ++G +V L C Y          GL I+W ++     H 
Sbjct: 19  LSAVRINGDG------QEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDPAHH 72

Query: 67  ERVVIWPFSNKNYIHGEL--YKNRVSIS-NNAEQSDASITIDQLTMADNGTYECSVSLMS 123
              V   + +K   HG L   + RV  + ++  Q DASI +  L ++D  TYEC V   +
Sbjct: 73  RENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTT 132

Query: 124 DLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYN---- 179
                   +V + V   P+ P C  EG    GN++ L C +  GS    Y W + +    
Sbjct: 133 ----MATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHY 188

Query: 180 ----------------ILNQE---QPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220
                           +  QE     + Q  +   + LK+IS    G Y CT +N  G  
Sbjct: 189 PYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYS 248

Query: 221 FCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIY---CCCCRG 263
            C + V V S S  + + +GI +G + AL  + + I+   CCCC G
Sbjct: 249 VCVVEVKV-SDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGG 293


>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
          Length = 298

 Score = 85.1 bits (209), Expect = 7e-17
 Identities = 71/249 (28%), Positives = 113/249 (45%), Gaps = 36/249 (14%)

Query: 23  SVETPQDVLRASQGKSVTLPC-TYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIH 81
           S    Q V+ A + +   L C T   + SSR   ++W KL      R V + +  +  + 
Sbjct: 30  SAPKDQQVVTAVEYQEAILACKTPKKTVSSR---LEWKKL-----GRSVSFVYYQQT-LQ 80

Query: 82  GELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKS-RVRLLVLVP 140
           G+ +KNR      AE  D +I I  +T +D G Y C VS  S+   N +   V L VLV 
Sbjct: 81  GD-FKNR------AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVA 133

Query: 141 PSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKN 200
           P+ P C +    + G  ++L CQ KEG+P P+Y+W +  I   E P     S       N
Sbjct: 134 PAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMN 193

Query: 201 ISTDT----------SGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALI 250
             T T          +G Y C + N  G + C     ++   +N++       G++AA++
Sbjct: 194 TKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCP-GKRMQVDDLNIS-------GIIAAVV 245

Query: 251 IIGIIIYCC 259
           ++ ++I  C
Sbjct: 246 VVALVISVC 254


>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
          Length = 355

 Score = 80.1 bits (196), Expect = 2e-15
 Identities = 78/296 (26%), Positives = 122/296 (41%), Gaps = 29/296 (9%)

Query: 19  VDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKN 78
           + A+++++        + +SV L C   T + + +  I+W K+    T  V    F NK 
Sbjct: 74  IGAVNLKSSNRTPVVQEFESVELSCII-TDSQTSDPRIEWKKIQDEQTTYVF---FDNK- 128

Query: 79  YIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL 138
            I G+L   R  I         S+ I  +T  D+  Y C V   +D +   +  + L V 
Sbjct: 129 -IQGDL-AGRAEILGKT-----SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQ 181

Query: 139 VPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSL 198
           V P  P C +     +G    L CQ  EG P P YSW R ++       A P        
Sbjct: 182 VKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFH 241

Query: 199 KNIST----------DTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAA 248
            N  T          D SG Y C +SN+ G+  C     +    +N+   +G  + V+A 
Sbjct: 242 LNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCE-EQEMEVYDLNIGGIIGGVLVVLAV 300

Query: 249 LIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDDYRQE 304
           L +I + I C   RG   N  +K+D     E+Y+ P +         +EE D+R +
Sbjct: 301 LALITLGICCAYRRGYFIN--NKQDG----ESYKNPGKPDGVNYIRTDEEGDFRHK 350


>gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]
          Length = 416

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 71/309 (22%), Positives = 136/309 (44%), Gaps = 35/309 (11%)

Query: 4   KMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLL 63
           ++ P ++ L      ++ +++ +P  ++  + GKS  L   Y +STSS   +++W     
Sbjct: 16  RLAPFVYLLLIQTDPLEGVNITSPVRLIHGTVGKSALLSVQY-SSTSSDRPVVKWQ---- 70

Query: 64  THTERVVIWPFSNKNYIHGEL---YKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS 120
              ++ V    S    + G L   Y++R+ +  N      S+ +  L +AD GTYE  +S
Sbjct: 71  LKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENG-----SLLLSDLQLADEGTYEVEIS 125

Query: 121 LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI--IGNNIQLTCQSKEGSPTPQYSWKRY 178
           +  D     K+ + L V VP S+P+  +   T+  +     L C S E    P Y+W + 
Sbjct: 126 ITDDTFTGEKT-INLTVDVPISRPQVLVASTTVLELSEAFTLNC-SHENGTKPSYTWLKD 183

Query: 179 N--ILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSN--EEGTQF-CNITVAVRSPSM 233
              +LN  + L  P   + +++  +  +    Y C   N   +G      ITV  RS   
Sbjct: 184 GKPLLNDSRMLLSP-DQKVLTITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRS--- 239

Query: 234 NVALYVGIAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLR---- 289
             +LY+ ++ G +  L+    ++  C C       + K + + + E  ++  ++L+    
Sbjct: 240 --SLYIILSTGGIFLLV---TLVTVCACWKPSKRKQKKLEKQNSLEYMDQNDDRLKPEAD 294

Query: 290 ELSREREEE 298
            L R  E+E
Sbjct: 295 TLPRSGEQE 303


>gi|67188443 CD276 antigen isoform a [Homo sapiens]
          Length = 534

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 77/309 (24%), Positives = 132/309 (42%), Gaps = 34/309 (11%)

Query: 11  TLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLL-LTHTERV 69
           T+   R    A+ V+ P+D + A  G   TL C++  S      L Q + +  LT T+++
Sbjct: 236 TITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSF--SPEPGFSLAQLNLIWQLTDTKQL 293

Query: 70  VIWPFSNKNYIHGELYKNRVSISNNA-EQSDASITIDQLTMADNGTYECSVSLMSDLEGN 128
           V      ++   G  Y NR ++  +   Q +AS+ + ++ +AD G++ C VS    +   
Sbjct: 294 VHSFTEGRD--QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS----IRDF 347

Query: 129 TKSRVRLLVLVPPSKPECGIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP 186
             + V L V  P SKP   +E    +  G+ + +TC S  G P  +  W+      Q  P
Sbjct: 348 GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD----GQGVP 403

Query: 187 L------AQPASGQPV----SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNV- 235
           L      +Q A+ Q +    S+  +    +G Y C   N    Q  + +V +    M   
Sbjct: 404 LTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFP 463

Query: 236 --ALY--VGIAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLREL 291
             AL+  VG++V ++A L+ +  +   C  + K    E+   A       E     L+ L
Sbjct: 464 PEALWVTVGLSVCLIALLVALAFV---CWRKIKQSCEEENAGAEDQDGEGEGSKTALQPL 520

Query: 292 SREREEEDD 300
                +EDD
Sbjct: 521 KHSDSKEDD 529



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 59/235 (25%), Positives = 104/235 (44%), Gaps = 27/235 (11%)

Query: 21  AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYI 80
           A+ V+ P+D + A  G   TL C++  S      L Q + +      + ++  F+ +   
Sbjct: 28  ALEVQVPEDPVVALVGTDATLCCSF--SPEPGFSLAQLNLIWQLTDTKQLVHSFA-EGQD 84

Query: 81  HGELYKNRVSISNNA-EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLV 139
            G  Y NR ++  +   Q +AS+ + ++ +AD G++ C VS    +     + V L V  
Sbjct: 85  QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS----IRDFGSAAVSLQVAA 140

Query: 140 PPSKPECGIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPL------AQPA 191
           P SKP   +E    +  G+ + +TC S +G P  +  W+      Q  PL      +Q A
Sbjct: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD----GQGVPLTGNVTTSQMA 196

Query: 192 SGQPV----SLKNISTDTSGYYICTSSNEEGTQFCNITVAV---RSPSMNVALYV 239
           + Q +    S+  +    +G Y C   N    Q  + +V +   RSP+  V + V
Sbjct: 197 NEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQV 251


>gi|13376852 CD276 antigen isoform b [Homo sapiens]
          Length = 316

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 72/298 (24%), Positives = 126/298 (42%), Gaps = 32/298 (10%)

Query: 21  AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYI 80
           A+ V+ P+D + A  G   TL C++  S      L Q + +      + ++  F+ +   
Sbjct: 28  ALEVQVPEDPVVALVGTDATLCCSF--SPEPGFSLAQLNLIWQLTDTKQLVHSFA-EGQD 84

Query: 81  HGELYKNRVSISNNA-EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLV 139
            G  Y NR ++  +   Q +AS+ + ++ +AD G++ C VS    +     + V L V  
Sbjct: 85  QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS----IRDFGSAAVSLQVAA 140

Query: 140 PPSKPECGIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPL------AQPA 191
           P SKP   +E    +  G+ + +TC S  G P  +  W+      Q  PL      +Q A
Sbjct: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD----GQGVPLTGNVTTSQMA 196

Query: 192 SGQPV----SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNV---ALY--VGIA 242
           + Q +    S+  +    +G Y C   N    Q  + +V +    M     AL+  VG++
Sbjct: 197 NEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLS 256

Query: 243 VGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD 300
           V ++A L+ +  +   C  + K    E+   A       E     L+ L     +EDD
Sbjct: 257 VCLIALLVALAFV---CWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDD 311


>gi|6005958 V-set and immunoglobulin domain containing 4 isoform 1
           [Homo sapiens]
          Length = 399

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 20/225 (8%)

Query: 8   VLWTLCAVRVTVDAIS---VETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLT 64
           +L  L    +TVD      +E P+ V    +G  V LPCTY       + L++W  L+  
Sbjct: 4   LLGLLLLGHLTVDTYGRPILEVPESVTGPWKG-DVNLPCTYDPLQGYTQVLVKW--LVQR 60

Query: 65  HTERVVIW-PFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMS 123
            ++ V I+   S+ ++I    Y+ R+ +S+     D S+ +  L M D   Y C V+  +
Sbjct: 61  GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKV-PGDVSLQLSTLEMDDRSHYTCEVTWQT 119

Query: 124 DLEGN-------TKSRVRLLVLVPPSKPECGIEGETI-IGNNIQLTCQSKEGSPTPQYSW 175
             +GN       T+ RV+ L +  P+       G T+  G  I L CQ++ GSP   Y W
Sbjct: 120 P-DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQAR-GSPPISYIW 177

Query: 176 KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220
            +    NQE    + A+   +  K      SG Y CT+  + G++
Sbjct: 178 YKQQTNNQEP--IKVATLSTLLFKPAVIADSGSYFCTAKGQVGSE 220


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 18/169 (10%)

Query: 91  ISNNAEQSDASITIDQLTMADN--GTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG- 147
           +S   + S+ ++T+  L++  N  G+YEC +   +    N    V L VL  P  P    
Sbjct: 187 VSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQ--NPASANRSDPVTLNVLYGPDGPTISP 244

Query: 148 IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSG 207
            +     G N+ L+C +    P  QYSW       Q        S Q + + NI+ + SG
Sbjct: 245 SKANYRPGENLNLSCHAASNPPA-QYSWFINGTFQQ--------STQELFIPNITVNNSG 295

Query: 208 YYICTSSNE----EGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIII 252
            Y+C + N       T    ITV+  +P ++    VGI +GV+A + +I
Sbjct: 296 SYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI 344


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 95  AEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII 154
           A+ +D S+ I  +   D G Y+C   + S+  G T++ V LLV   P             
Sbjct: 448 AQLADLSLEISGIIPTDGGRYQC---VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQ 504

Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSS 214
           G  ++++C S  G PTP  SW R +   QE       +   + ++ ++ + +G Y C ++
Sbjct: 505 GVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 563

Query: 215 NEEGTQFCNITVAVRSPSMNVAL--YVGIAVGVVAALI 250
           NE GT    +T+    P    A+   V +AVG  A L+
Sbjct: 564 NEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 601



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 5/128 (3%)

Query: 92  SNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGE 151
           S ++ ++D S+ +D+      G Y C   + ++  G+    V L+V VPP          
Sbjct: 813 SRHSIRADGSLHLDRALQEHAGRYSC---VATNTAGSQHRDVELVVQVPPRIHPTATHHI 869

Query: 152 TIIGNNIQLTCQSKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYI 210
           T  G    L C +  G P P  +W K  N L    P    +    + +   S   +G Y+
Sbjct: 870 TNEGVPASLPCVAS-GVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYV 928

Query: 211 CTSSNEEG 218
           CT++N  G
Sbjct: 929 CTATNTVG 936



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 16/131 (12%)

Query: 99   DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI----- 153
            + ++ I Q +  D G Y C+ +   +  G +   +RL V   P     G     +     
Sbjct: 911  EGTLLIAQPSAQDAGAYVCTAT---NTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVT 967

Query: 154  --IGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQP---VSLKNISTDTSGY 208
               G  + L C++K GSP P  +W + +      P+       P   + L  +    SG+
Sbjct: 968  AKAGEEVTLDCEAK-GSPPPLVTWTKDS--RPVPPITNRYGLLPSGSLRLAQVQVGDSGH 1024

Query: 209  YICTSSNEEGT 219
            Y CT+SN  G+
Sbjct: 1025 YECTASNPAGS 1035



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 20/149 (13%)

Query: 96  EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIG 155
           E  ++S  I + + A+ GTYEC+    +   G  +++ +++V  PP +           G
Sbjct: 358 ESGNSSWEILRASKAEEGTYECTAVSRA---GTGRAKAQIVVTDPPPQLVPAPNVTVSPG 414

Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGY------ 208
               L+C+    +P        YN+         PAS G+   L ++S + SG       
Sbjct: 415 ETAVLSCRVLGEAP--------YNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGG 466

Query: 209 -YICTSSNEEGTQFCNITVAVR-SPSMNV 235
            Y C +SN  G    ++ + VR +P +++
Sbjct: 467 RYQCVASNANGVTRASVWLLVREAPQVSI 495



 Score = 35.0 bits (79), Expect = 0.088
 Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 18/148 (12%)

Query: 93  NNAEQSDASITI-DQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL--VPPSKPECGIE 149
           + + Q D+ +   + +   D   Y C      ++ G  ++  RL+V    PP        
Sbjct: 720 SRSRQPDSGVLFFESVAPEDQAPYVCEAR---NVFGKVQAEARLIVTGHAPPQIASSAPT 776

Query: 150 GETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVS------LKNIST 203
              + G  + L C    G P P+  W     L   +PL  P S   +       L     
Sbjct: 777 VRVLEGQPVSLPCIVLAGRPLPERHW-----LKDGRPLP-PGSRHSIRADGSLHLDRALQ 830

Query: 204 DTSGYYICTSSNEEGTQFCNITVAVRSP 231
           + +G Y C ++N  G+Q  ++ + V+ P
Sbjct: 831 EHAGRYSCVATNTAGSQHRDVELVVQVP 858


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 95  AEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII 154
           A+ +D S+ I  +   D G Y+C   + S+  G T++ V LLV   P             
Sbjct: 565 AQLADLSLEISGIIPTDGGRYQC---VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQ 621

Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSS 214
           G  ++++C S  G PTP  SW R +   QE       +   + ++ ++ + +G Y C ++
Sbjct: 622 GVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 680

Query: 215 NEEGTQFCNITVAVRSPSMNVAL--YVGIAVGVVAALI 250
           NE GT    +T+    P    A+   V +AVG  A L+
Sbjct: 681 NEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 718



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 9/131 (6%)

Query: 101  SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160
            S+ + Q+ + D+G YEC+ S   +  G+   R  L V VPP         + ++G  + L
Sbjct: 1083 SLRLAQVQVGDSGHYECTAS---NPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDL 1139

Query: 161  TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220
             C + EG+P PQ SW +  ++ Q +          V    I T  +G Y C +SN  G  
Sbjct: 1140 NCVA-EGNPEPQLSWSKDGVVLQGR-----GPQGSVHFAAIRTSDAGRYRCEASNSAGVD 1193

Query: 221  FCNITVAVRSP 231
               + + V  P
Sbjct: 1194 AWEVELRVLEP 1204



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 39/142 (27%), Positives = 64/142 (45%), Gaps = 7/142 (4%)

Query: 90   SISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIE 149
            S  +  E   + + ++    A +G Y C   + S   G    +  + V VPP        
Sbjct: 1640 SNESRLETDGSVLRLESPGEASSGLYSC---VASSPAGEAVLQYSVEVQVPPQLLVAEGL 1696

Query: 150  GE--TIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTS 206
            G+  TI+G  ++L CQ+  GSP P   W +     +E    Q AS G  + + ++  D S
Sbjct: 1697 GQVTTIVGQPLELPCQAS-GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHS 1755

Query: 207  GYYICTSSNEEGTQFCNITVAV 228
            G + C ++NE GT    + V+V
Sbjct: 1756 GLFACQATNEAGTAGAEVEVSV 1777



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 40/156 (25%), Positives = 64/156 (41%), Gaps = 32/156 (20%)

Query: 99   DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGET--IIGN 156
            + S+ +  ++ AD+G YEC  +   +  G+T  R +L+V VPPS  E G +     + G 
Sbjct: 1260 EGSLFLASVSPADSGDYECQAT---NEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQ 1316

Query: 157  NIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS---------------------GQP 195
            ++ L C +  G P P+  W     L   Q +  P                       GQ 
Sbjct: 1317 SLTLECDAN-GFPVPEIVW-----LKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS 1370

Query: 196  VSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSP 231
            +    I    SG Y C + N+ GT   +  + V +P
Sbjct: 1371 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP 1406



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 5/131 (3%)

Query: 102  ITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLT 161
            + I+++ + D G Y C+ +   +L G +K  V L VLVPP+     +    +   ++ L 
Sbjct: 1850 LQIEKVDLRDEGIYTCAAT---NLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLE 1906

Query: 162  CQSKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220
            C +  G P P  SW K +  ++    +     G+ + ++      +G Y C +SN  G+ 
Sbjct: 1907 CLA-SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST 1965

Query: 221  FCNITVAVRSP 231
                 + V  P
Sbjct: 1966 ELRYGLRVNVP 1976



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 8/135 (5%)

Query: 101  SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI--IGNNI 158
            S+   ++   D+G Y C     +   G  +    LLVL PPS    G   E +   G ++
Sbjct: 1370 SLHFPRIQEGDSGLYSCRAENQA---GTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADV 1426

Query: 159  QLTCQSKEGSPTPQYSWK--RYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNE 216
            +L C +  G PTPQ  W   R  +L     L     GQ + +        G Y C + + 
Sbjct: 1427 ELQCWTS-GVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSP 1485

Query: 217  EGTQFCNITVAVRSP 231
             G Q  +  + V +P
Sbjct: 1486 AGQQARDFQLRVHAP 1500



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 19/144 (13%)

Query: 107  LTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII----GNNIQLTC 162
            L + D G Y C   L     G  +   R+ V  PP+    G  G   +       + L C
Sbjct: 3549 LRVRDAGLYTC---LAESPAGAIEKSFRVRVQAPPNI--VGPRGPRFVVGLAPGQLVLEC 3603

Query: 163  QSKEGSPTPQYSWKRYNILNQEQPLAQ-PASGQPVSLKNISTDTSGYYICTSSNEEGTQF 221
             S E  P P+ +W R  I+ QE    Q P  G+ + L+ +ST  SG Y CT+ N  G+  
Sbjct: 3604 -SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTS 3662

Query: 222  CNITVAVRS--------PSMNVAL 237
                V + +        P++NV++
Sbjct: 3663 VAFRVEIHTVPTIRSGPPAVNVSV 3686



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 5/128 (3%)

Query: 92   SNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGE 151
            S ++ ++D S+ +D+      G Y C   + ++  G+    V L+V VPP          
Sbjct: 930  SRHSIRADGSLHLDRALQEHAGRYSC---VATNTAGSQHRDVELVVQVPPRIHPTATHHI 986

Query: 152  TIIGNNIQLTCQSKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYI 210
            T  G    L C +  G P P  +W K  N L    P    +    + +   S   +G Y+
Sbjct: 987  TNEGVPASLPCVAS-GVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYV 1045

Query: 211  CTSSNEEG 218
            CT++N  G
Sbjct: 1046 CTATNTVG 1053



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 11/145 (7%)

Query: 110  ADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEG---ETIIGNNIQLTCQSKE 166
            +D G Y C  S   +  G  +   RL V VPP+    G      + + G  + L C ++ 
Sbjct: 1566 SDAGVYTCKAS---NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVAR- 1621

Query: 167  GSPTPQYSWKRYNILNQEQPLAQ-PASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNIT 225
            G P+P  SW    +   E   ++    G  + L++    +SG Y C +S+  G      +
Sbjct: 1622 GHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYS 1681

Query: 226  VAVRSPSMNVALYVGIAVGVVAALI 250
            V V+ P     L V   +G V  ++
Sbjct: 1682 VEVQVPPQ---LLVAEGLGQVTTIV 1703



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 111  DNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPT 170
            D G Y C   +  +  G+   + RL+V VPP       +  T  G++  L C+++ GSP 
Sbjct: 4011 DAGNYLC---IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKAR-GSPE 4066

Query: 171  PQYSWKRYN--ILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEG 218
            P  +W +    +   E       SG+ + +KN+    +G Y CT+ N  G
Sbjct: 4067 PNITWDKDGQPVSGAEGKFTIQPSGE-LLVKNLEGQDAGTYTCTAENAVG 4115



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 20/139 (14%)

Query: 99   DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII---G 155
            + S+TI +    D G Y+C    +++ E     +V +LVL   S P   +E + +    G
Sbjct: 4270 NGSLTIHRTERDDAGRYQC----LAENEMGVAKKVVILVL--QSAPVFQVEPQDMTVRSG 4323

Query: 156  NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVS-----LKNISTDTSGYYI 210
            +++ L CQ+  G PTP   W     L   QPL      + +      L+N+ T  +G Y 
Sbjct: 4324 DDVALRCQAT-GEPTPTIEW-----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 4377

Query: 211  CTSSNEEGTQFCNITVAVR 229
            C + N  G+      + VR
Sbjct: 4378 CVAHNLLGSATARAFLVVR 4396



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 51/230 (22%), Positives = 88/230 (38%), Gaps = 44/230 (19%)

Query: 12   LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQW--DKLLLTHTERV 69
            L  +RV V         + + A    SV+LPC  H   +     + W  D   L+  E V
Sbjct: 2928 LFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE---VTWYKDSQALSLGEEV 2984

Query: 70   VIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNT 129
             + P ++                        ++ + +  ++D+G Y C      +  G  
Sbjct: 2985 FLLPGTH------------------------TLQLGRARLSDSGMYTCEAL---NAAGRD 3017

Query: 130  KSRVRLLVLVPPSKPEC--GIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQ 185
            +  V+L VLVPP+  +   G +   ++  G+   L+C++ +  P P  +W +     Q  
Sbjct: 3018 QKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET-DALPEPTVTWYKDG---QPL 3073

Query: 186  PLAQPAS----GQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSP 231
             LAQ       GQ + ++       G Y C  SN  G      T+ V+ P
Sbjct: 3074 VLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP 3123



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/142 (26%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 101  SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPS-----KPECGIEGETIIG 155
            S+ +++   A  G Y C   +  +L G  + +  L VLVPP       P   I     + 
Sbjct: 2313 SLHVERAQAAHTGRYSC---VAENLAGRAERKFELSVLVPPELIGDLDPLTNITAA--LH 2367

Query: 156  NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQP------ASGQPVSLKNISTDTSGYY 209
            + + L C++  G P P   W R      E+P++        A G  + +       SG Y
Sbjct: 2368 SPLTLLCEAM-GIPPPAIRWFR-----GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLY 2421

Query: 210  ICTSSNEEGTQFCNITVAVRSP 231
             C +SNE G    N +V V  P
Sbjct: 2422 SCLASNEAGEARRNFSVEVLVP 2443



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 26/119 (21%), Positives = 53/119 (44%), Gaps = 5/119 (4%)

Query: 102  ITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLT 161
            + +  L+ AD+G Y C+     +  G+T    R+ +   P+           +     L 
Sbjct: 3637 LQLQALSTADSGDYSCTAR---NAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLP 3693

Query: 162  CQSKEGSPTPQYSWKRYNI-LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGT 219
            CQ+ +G P P  SW++  + L+   P  +      + ++ +    +G+Y+C +SN  G+
Sbjct: 3694 CQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGS 3751



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 7/113 (6%)

Query: 109  MADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNN--IQLTCQSKE 166
            + D G Y+C   +     G      +L V  PP+       GE  +  +  +QL C+++ 
Sbjct: 1472 VGDEGRYQC---VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEAR- 1527

Query: 167  GSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEG 218
            G PTP  +W K   +L     +     G+ + L    +  +G Y C +SN  G
Sbjct: 1528 GVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 1580



 Score = 37.4 bits (85), Expect = 0.018
 Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 14/158 (8%)

Query: 107  LTMADN-GTYECSVSLMSDLEGNTKSRVRLLVLVPP---SKPECGIEGETI-IGNNIQLT 161
            L  A+N G Y C  S   +  G       LLVL PP      E  +E  T+   + + L 
Sbjct: 2810 LVRAENAGRYSCKAS---NEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ 2866

Query: 162  CQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGYYICTSSNEEGTQ 220
            C +  G+P P  SW +  +     P  Q    GQ + +       +  Y+C + N+ G+ 
Sbjct: 2867 CPAL-GNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 2925

Query: 221  FCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIYC 258
                T+ V+ P        G+ +  V A++   + + C
Sbjct: 2926 EKLFTLRVQVPPR----IAGLDLEQVTAILNSSVSLPC 2959



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 12/131 (9%)

Query: 111  DNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKP------ECGI-EGETIIGNNIQLTCQ 163
            D G Y C V+  ++L G       + VL+PPS        E G+ E +T + + + L C+
Sbjct: 2606 DAGQYTCVVT--NEL-GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECE 2662

Query: 164  SKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFC 222
            S    P P   W K    +     L     G+ + ++      SG Y+C ++N  G    
Sbjct: 2663 SW-AVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQ 2721

Query: 223  NITVAVRSPSM 233
            +  V ++ P M
Sbjct: 2722 DFNVLIQVPPM 2732



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 8/135 (5%)

Query: 101  SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII---GNN 157
            S+ +  L  +D G Y C   +  +  G       + VLVPP+  +      T++   G  
Sbjct: 3274 SLVLKGLRASDAGAYTC---VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL 3330

Query: 158  IQLTCQSKEGSPTPQYSWKRYNI-LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNE 216
            + + C  + GSP    SW +  + L   Q      SG  + +  +    +G + C +++ 
Sbjct: 3331 VTMVCPVR-GSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASP 3389

Query: 217  EGTQFCNITVAVRSP 231
             G    N T+ V+ P
Sbjct: 3390 AGVADRNFTLQVQVP 3404



 Score = 35.8 bits (81), Expect = 0.052
 Identities = 32/155 (20%), Positives = 59/155 (38%), Gaps = 33/155 (21%)

Query: 102  ITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG-------------- 147
            + I    ++D+G Y C   + +++ G       +L+ VPP   + G              
Sbjct: 2695 LQIQPTQVSDSGRYLC---VATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEE 2751

Query: 148  -----IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQP------ASGQPV 196
                  E   I+ NN           P P  +W R     ++QPL+          G+ +
Sbjct: 2752 ARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR-----EDQPLSAGDEVSVLQGGRVL 2806

Query: 197  SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSP 231
             +  +  + +G Y C +SNE G  + +  + V +P
Sbjct: 2807 QIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTP 2841



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 20/149 (13%)

Query: 96  EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIG 155
           E  ++S  I + + A+ GTYEC+    +   G  +++ +++V  PP +           G
Sbjct: 475 ESGNSSWEILRASKAEEGTYECTAVSRA---GTGRAKAQIVVTDPPPQLVPAPNVTVSPG 531

Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGY------ 208
               L+C+    +P        YN+         PAS G+   L ++S + SG       
Sbjct: 532 ETAVLSCRVLGEAP--------YNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGG 583

Query: 209 -YICTSSNEEGTQFCNITVAVR-SPSMNV 235
            Y C +SN  G    ++ + VR +P +++
Sbjct: 584 RYQCVASNANGVTRASVWLLVREAPQVSI 612



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 29/136 (21%), Positives = 53/136 (38%), Gaps = 17/136 (12%)

Query: 91   ISNNAEQSDASITIDQLTMA--DNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148
            ++    + D   T+ +  ++  D+GTY C          N   R + +  V   +    +
Sbjct: 4169 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAE-------NRVGRTQAVSFVHVKEAPV-L 4220

Query: 149  EGETI------IGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNIS 202
            +GE        +G +IQL C  + G P P   W +  +  +   L        +++    
Sbjct: 4221 QGEAFSYLVEPVGGSIQLDCVVR-GDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTE 4279

Query: 203  TDTSGYYICTSSNEEG 218
             D +G Y C + NE G
Sbjct: 4280 RDDAGRYQCLAENEMG 4295



 Score = 35.0 bits (79), Expect = 0.088
 Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 18/148 (12%)

Query: 93  NNAEQSDASITI-DQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL--VPPSKPECGIE 149
           + + Q D+ +   + +   D   Y C      ++ G  ++  RL+V    PP        
Sbjct: 837 SRSRQPDSGVLFFESVAPEDQAPYVCEAR---NVFGKVQAEARLIVTGHAPPQIASSAPT 893

Query: 150 GETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVS------LKNIST 203
              + G  + L C    G P P+  W     L   +PL  P S   +       L     
Sbjct: 894 VRVLEGQPVSLPCIVLAGRPLPERHW-----LKDGRPLP-PGSRHSIRADGSLHLDRALQ 947

Query: 204 DTSGYYICTSSNEEGTQFCNITVAVRSP 231
           + +G Y C ++N  G+Q  ++ + V+ P
Sbjct: 948 EHAGRYSCVATNTAGSQHRDVELVVQVP 975



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 5/118 (4%)

Query: 102  ITIDQLTMADNGTYEC-SVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160
            +T+     +D+G Y C +VS +    G  +  V L V +PPS     +    +   ++ L
Sbjct: 2035 LTLASARASDSGRYSCVAVSAV----GEDRQDVVLQVHMPPSILGEELNVSVVANESVAL 2090

Query: 161  TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEG 218
             CQS    P     WK    L     +   A    + +       +G+Y C + N+ G
Sbjct: 2091 ECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAG 2148



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/131 (20%), Positives = 48/131 (36%), Gaps = 4/131 (3%)

Query: 101  SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160
            ++ I Q      G Y CS     +  G     V L V   P           +    + L
Sbjct: 3911 ALEIGQALPIHAGRYTCSAR---NSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLL 3967

Query: 161  TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220
             C++  G P P  +W++  +        Q   G  + + + S + +G Y+C + N  G+ 
Sbjct: 3968 PCEAS-GIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSA 4026

Query: 221  FCNITVAVRSP 231
                 + V+ P
Sbjct: 4027 MGKTRLVVQVP 4037



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 30/132 (22%), Positives = 51/132 (38%), Gaps = 10/132 (7%)

Query: 106  QLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPS-----KPECGIEGETIIGNNIQL 160
            Q  ++  G Y C   + ++  G      +L VL+ P+     +     E    + N I L
Sbjct: 2505 QANLSSAGHYSC---IAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISL 2561

Query: 161  TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASG-QPVSLKNISTDTSGYYICTSSNEEGT 219
             C++    P+P  +W +     +     Q   G   + + N   + +G Y C  +NE G 
Sbjct: 2562 ICEAL-AFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGE 2620

Query: 220  QFCNITVAVRSP 231
               N  V V  P
Sbjct: 2621 AVKNYHVEVLIP 2632


>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
           sapiens]
          Length = 790

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%)

Query: 95  AEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII 154
           A+ +D S+ I  +   D G Y+C   + S+  G T++ V LLV   P             
Sbjct: 564 AQLADLSLEISGIIPTDGGRYQC---VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQ 620

Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSS 214
           G  ++++C S  G PTP  SW R +   QE       +   + ++ ++ + +G Y C ++
Sbjct: 621 GVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 679

Query: 215 NEEGTQFCNITVAVRSPSMNVAL--YVGIAVGVVAALI 250
           NE GT    +T+    P    A+   V +AVG  A L+
Sbjct: 680 NEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 717



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 20/149 (13%)

Query: 96  EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIG 155
           E  ++S  I + + A+ GTYEC+    +   G  +++ +++V  PP +           G
Sbjct: 474 ESGNSSWEILRASKAEEGTYECTAVSRA---GTGRAKAQIVVTDPPPQLVPAPNVTVSPG 530

Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGY------ 208
               L+C+    +P        YN+         PAS G+   L ++S + SG       
Sbjct: 531 ETAVLSCRVLGEAP--------YNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGG 582

Query: 209 -YICTSSNEEGTQFCNITVAVR-SPSMNV 235
            Y C +SN  G    ++ + VR +P +++
Sbjct: 583 RYQCVASNANGVTRASVWLLVREAPQVSI 611


>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
          Length = 316

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)

Query: 29  DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88
           D +   QG+S TL CT     + R   +    +L    ++  + P              R
Sbjct: 43  DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87

Query: 89  VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148
           V + +N  Q+  SI I  + + D G Y CSV   +D    T SRV L+V V P   E   
Sbjct: 88  VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143

Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208
           +     GNNI LTC +  G P P  +W+  +     + +   +  + + ++ I+ + SG 
Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198

Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244
           Y C++SN+        + V V   P ++ A   G+ VG
Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%)

Query: 99  DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158
           D  + I  +T   +G YECS S  +D+      RV++ V  PP   E    G  + G   
Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239

Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214
            L C++    P+ ++ W + +    E         +P   K    N+S    G Y C +S
Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298

Query: 215 NEEG 218
           N+ G
Sbjct: 299 NKLG 302


>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
          Length = 355

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)

Query: 29  DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88
           D +   QG+S TL CT     + R   +    +L    ++  + P              R
Sbjct: 43  DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87

Query: 89  VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148
           V + +N  Q+  SI I  + + D G Y CSV   +D    T SRV L+V V P   E   
Sbjct: 88  VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143

Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208
           +     GNNI LTC +  G P P  +W+  +     + +   +  + + ++ I+ + SG 
Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198

Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244
           Y C++SN+        + V V   P ++ A   G+ VG
Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%)

Query: 99  DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158
           D  + I  +T   +G YECS S  +D+      RV++ V  PP   E    G  + G   
Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239

Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214
            L C++    P+ ++ W + +    E         +P   K    N+S    G Y C +S
Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298

Query: 215 NEEG 218
           N+ G
Sbjct: 299 NKLG 302


>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
          Length = 344

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)

Query: 29  DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88
           D +   QG+S TL CT     + R   +    +L    ++  + P              R
Sbjct: 43  DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87

Query: 89  VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148
           V + +N  Q+  SI I  + + D G Y CSV   +D    T SRV L+V V P   E   
Sbjct: 88  VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143

Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208
           +     GNNI LTC +  G P P  +W+  +     + +   +  + + ++ I+ + SG 
Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198

Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244
           Y C++SN+        + V V   P ++ A   G+ VG
Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%)

Query: 99  DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158
           D  + I  +T   +G YECS S  +D+      RV++ V  PP   E    G  + G   
Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239

Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214
            L C++    P+ ++ W + +    E         +P   K    N+S    G Y C +S
Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298

Query: 215 NEEG 218
           N+ G
Sbjct: 299 NKLG 302


>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
          Length = 344

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%)

Query: 29  DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88
           D +   QG+S TL CT     + R   +    +L    ++  + P              R
Sbjct: 43  DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87

Query: 89  VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148
           V + +N  Q+  SI I  + + D G Y CSV   +D    T SRV L+V V P   E   
Sbjct: 88  VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143

Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208
           +     GNNI LTC +  G P P  +W+  +     + +   +  + + ++ I+ + SG 
Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198

Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244
           Y C++SN+        + V V   P ++ A   G+ VG
Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%)

Query: 99  DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158
           D  + I  +T   +G YECS S  +D+      RV++ V  PP   E    G  + G   
Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239

Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214
            L C++    P+ ++ W + +    E         +P   K    N+S    G Y C +S
Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298

Query: 215 NEEG 218
           N+ G
Sbjct: 299 NKLG 302


>gi|66346706 neuronal growth regulator 1 [Homo sapiens]
          Length = 354

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 12/130 (9%)

Query: 88  RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147
           RVSIS    + D S+ I  + + D+G Y CSV            +V L V VPP   +  
Sbjct: 90  RVSIST-LNKRDYSLQIQNVDVTDDGPYTCSVQTQ---HTPRTMQVHLTVQVPPKIYDIS 145

Query: 148 IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQP-ASGQPVSLKNISTDTS 206
            +     G N+ LTC +  G P P  SW+  +      P A+P  +GQ + +  I+ D +
Sbjct: 146 NDMTVNEGTNVTLTCLA-TGKPEPSISWRHIS------PSAKPFENGQYLDIYGITRDQA 198

Query: 207 GYYICTSSNE 216
           G Y C++ N+
Sbjct: 199 GEYECSAEND 208


>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
          Length = 510

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 45/167 (26%), Positives = 70/167 (41%), Gaps = 17/167 (10%)

Query: 160 LTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGT 219
           L C S EG P P Y+W R   L+   P      G  +    ++T+ SG Y+C  SNE  +
Sbjct: 268 LKCLS-EGQPPPSYNWTR---LDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSS 323

Query: 220 QFCNITVAVRSPSMNVALYVG------IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKED 273
           +   +TV V  P  +    V       + VGV+AAL+   +++          +   +  
Sbjct: 324 RDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLM-----SRYHRRK 378

Query: 274 ARPNREAYEEPPEQLRE--LSREREEEDDYRQEEQRSTGRESPDHLD 318
           A+   + YEE     RE  + R      D R + + S G  +  H D
Sbjct: 379 AQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPD 425



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 50/180 (27%), Positives = 74/180 (41%), Gaps = 12/180 (6%)

Query: 4   KMW-PVLWTLCAVRVT-----VDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQ 57
           +MW P  W L  + +        A  +ET  DV+    G+   LPC Y   +  + G + 
Sbjct: 8   EMWGPEAWLLLLLLLASFTGRCPAGELET-SDVVTVVLGQDAKLPCFYRGDSGEQVGQVA 66

Query: 58  WDKLLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQS-DASITIDQLTMADNGTYE 116
           W ++      + +    S         Y+ RV          D S+ +     AD G YE
Sbjct: 67  WARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYE 126

Query: 117 CSVSLMSDLEGNTKSRVRLLVLVPP-SKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSW 175
           C VS      G+ ++R+RL VLVPP      G   E   G  +  +C + EGSP P  +W
Sbjct: 127 CRVSTFP--AGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASC-TAEGSPAPSVTW 183


>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
           precursor [Homo sapiens]
          Length = 2012

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 59/235 (25%), Positives = 96/235 (40%), Gaps = 34/235 (14%)

Query: 7   PVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHT 66
           P L T  +V VTV       P +  R S G+ V +PC     +      I W K      
Sbjct: 581 PQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCV--VVSGDLPITITWQK------ 632

Query: 67  ERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLE 126
                          G      + ++ +     +S+ I  L++  NG Y C   +  +  
Sbjct: 633 --------------DGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC---IARNEA 675

Query: 127 GNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWK--RYNILNQE 184
              + + +L+V VPP       + + I G  + L C S EG P P   WK  +   + Q 
Sbjct: 676 AAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNC-SAEGYPVPTIVWKFSKGAGVPQF 734

Query: 185 QPLA-----QPASGQPVSLKNISTDTSGYYICTSSNEEGTQFC-NITVAVRSPSM 233
           QP+A     Q  S   + +K++  + SGYY+C  SN+ G     ++ + V+ P+M
Sbjct: 735 QPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAM 789



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 8/110 (7%)

Query: 115 YECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEG----ETIIGNNIQLTCQSKEGSPT 170
           Y C        E    +  RL V  P +     ++G    + + G  ++L C++  G P 
Sbjct: 195 YRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKAL-GHPE 253

Query: 171 PQYSWKRYNI-LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGT 219
           P Y W + N+ L       +  +G  + ++NI    SG Y+C  SN  GT
Sbjct: 254 PDYRWLKDNMPLELSGRFQKTVTG--LLIENIRPSDSGSYVCEVSNRYGT 301



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 27/148 (18%)

Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPEC-GIEGETIIG--NN 157
           ++ +D +  +D G Y+C V      +    ++  + V++    P+      E ++     
Sbjct: 369 NLIMDHMVKSDGGAYQCFVR-----KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEP 423

Query: 158 IQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS----------GQPVSLKNISTDT-- 205
           + L C  K G+P P  +W        + P+ +  S          G  VS  NIS+    
Sbjct: 424 VSLMCNVK-GTPLPTITWTL-----DDDPILKGGSHRISQMITSEGNVVSYLNISSSQVR 477

Query: 206 -SGYYICTSSNEEGTQFCNITVAVRSPS 232
             G Y CT++N  G       + VR P+
Sbjct: 478 DGGVYRCTANNSAGVVLYQARINVRGPA 505



 Score = 32.7 bits (73), Expect = 0.44
 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 4/89 (4%)

Query: 89  VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148
           + +S   +++   + I+ +  +D+G+Y C V   S+  G  K   RL V  P        
Sbjct: 265 LELSGRFQKTVTGLLIENIRPSDSGSYVCEV---SNRYGTAKVIGRLYVKQPLKATISPR 321

Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKR 177
           + ++ +G+ + L+C S  G+   + SW R
Sbjct: 322 KVKSSVGSQVSLSC-SVTGTEDQELSWYR 349


>gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]
          Length = 540

 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 33/178 (18%)

Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS---------GQPVSLKNISTDT 205
           G N+ LTCQ     P  +  W R   L Q + + QP+S            +++ N S D 
Sbjct: 324 GGNVTLTCQVSGAYPPAKILWLRN--LTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDL 381

Query: 206 S-GYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIYC------ 258
             GYYIC + +  G +   I ++V+ P     L +G  VG + +L+++G+ I        
Sbjct: 382 DEGYYICRADSPVGVREMEIWLSVKEP-----LNIGGIVGTIVSLLLLGLAIISGLLLHY 436

Query: 259 ----CCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDDYRQEEQRSTGRE 312
               C   G     ++ +D     ++ EE  E+      E EEED    E++ +  RE
Sbjct: 437 SPVFCWKVGNTSRGQNMDDVMVLVDSEEEEEEE------EEEEEDAAVGEQEGARERE 488



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 113 GTYECSVSLMSDLEGNTKSRVRLLVLVPP-SKPECGIEGETIIGN-NIQLTCQSKEGSPT 170
           G Y C ++L    + + K    LLV  PP S P+C  +  +  G+  +QLTC+   G P 
Sbjct: 197 GNYTC-LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMAS--GSFMLQLTCRWDGGYPD 253

Query: 171 PQYSW 175
           P + W
Sbjct: 254 PDFLW 258


>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 22/172 (12%)

Query: 88  RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147
           R+ +SN     + ++T+  +T  D   Y C +   + +  N    V L VL  P  P   
Sbjct: 546 RLQLSNG----NRTLTLFNVTRNDARAYVCGIQ--NSVSANRSDPVTLDVLYGPDTPIIS 599

Query: 148 IEGETII-GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTS 206
               + + G N+ L+C S   +P+PQYSW+   I  Q          Q + +  I+ + +
Sbjct: 600 PPDSSYLSGANLNLSCHSAS-NPSPQYSWRINGIPQQHT--------QVLFIAKITPNNN 650

Query: 207 GYYIC------TSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIII 252
           G Y C      T  N    +   ++ +  SP ++    VGI +GV+  + +I
Sbjct: 651 GTYACFVSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 702



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 20/149 (13%)

Query: 88  RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147
           R+ +SN     + ++T+  +T  D  +Y+C     + +       V L VL  P  P   
Sbjct: 190 RLQLSNG----NRTLTLFNVTRNDTASYKCETQ--NPVSARRSDSVILNVLYGPDAPTIS 243

Query: 148 -IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTS 206
            +      G N+ L+C +    P  QYSW       Q        S Q + + NI+ + S
Sbjct: 244 PLNTSYRSGENLNLSCHAASNPPA-QYSWFVNGTFQQ--------STQELFIPNITVNNS 294

Query: 207 GYYICTSSNEE----GTQFCNITVAVRSP 231
           G Y C + N +     T    ITV    P
Sbjct: 295 GSYTCQAHNSDTGLNRTTVTTITVYAEPP 323



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 20/154 (12%)

Query: 88  RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147
           R+ +SN+    + ++T+  +T  D G YEC +   + L  +    V L VL  P  P   
Sbjct: 368 RLQLSND----NRTLTLLSVTRNDVGPYECGIQ--NKLSVDHSDPVILNVLYGPDDPTIS 421

Query: 148 IEGETII-GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTS 206
                   G N+ L+C +    P  QYSW     + Q          Q + + NI+   S
Sbjct: 422 PSYTYYRPGVNLSLSCHAASNPPA-QYSWLIDGNIQQHT--------QELFISNITEKNS 472

Query: 207 GYYICTSSNEEG----TQFCNITVAVRSPSMNVA 236
           G Y C ++N       T    ITV+   P  +++
Sbjct: 473 GLYTCQANNSASGHSRTTVKTITVSAELPKPSIS 506


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 9/138 (6%)

Query: 101  SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160
            ++ +D LT  D+G Y C     +   GN  +  ++LV VPP           + G + Q 
Sbjct: 6071 ALILDSLTGVDSGQYMC---FAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDAQF 6127

Query: 161  TCQSKEGSPTPQYSWKRYNIL----NQEQPLAQPASGQPV-SLKNISTDTSGYYICTSSN 215
            TC + EG+P PQ  W +   L    N+ Q L++P SG  V  ++  S +  G Y C   N
Sbjct: 6128 TC-TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 6186

Query: 216  EEGTQFCNITVAVRSPSM 233
              G+   +  + ++SP +
Sbjct: 6187 RLGSARASAELRIQSPML 6204



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 14/83 (16%)

Query: 154 IGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP--------LAQPASGQPVSLKNISTDT 205
           +G +  L+CQ   G+PTPQ SW++      +QP        LAQ      +++ +++   
Sbjct: 23  VGKDATLSCQIV-GNPTPQVSWEK-----DQQPVAAGARFRLAQDGDLYRLTILDLALGD 76

Query: 206 SGYYICTSSNEEGTQFCNITVAV 228
           SG Y+C + N  G  F  + + V
Sbjct: 77  SGQYVCRARNAIGEAFAAVGLQV 99



 Score = 36.6 bits (83), Expect = 0.030
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 6/99 (6%)

Query: 140 PPSKPECGIEGETII-GNNIQLTCQSKEGSPTPQYSWKRYNILNQE--QPLAQPASGQPV 196
           P S P  G    T+  G + +L+C    G P P+  WK+   L  E  + +    + +  
Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVT-GEPKPETVWKKDGQLVTEGRRHVVYEDAQENF 294

Query: 197 SLKNISTDTS--GYYICTSSNEEGTQFCNITVAVRSPSM 233
            LK +    S  G Y CT+SN  G  + ++ V VR P++
Sbjct: 295 VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAV 333



 Score = 33.5 bits (75), Expect = 0.26
 Identities = 37/154 (24%), Positives = 59/154 (38%), Gaps = 30/154 (19%)

Query: 101  SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLV-----------------LVPPSK 143
            ++ I  +T  D+G Y    + +S+  G   S  RLLV                 LVPP  
Sbjct: 5317 TLEIISVTREDSGQY---AAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRM 5373

Query: 144  PECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI------LNQEQP---LAQPASGQ 194
             E     +   G++I  + +  EG P P   W R         +  + P   +A  A   
Sbjct: 5374 LERFTPKKVKKGSSITFSVKV-EGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432

Query: 195  PVSLKNISTDTSGYYICTSSNEEGTQFCNITVAV 228
             + L ++     G Y C +SN  G   C+ ++ V
Sbjct: 5433 SLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score = 32.3 bits (72), Expect = 0.57
 Identities = 37/181 (20%), Positives = 74/181 (40%), Gaps = 29/181 (16%)

Query: 34  SQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNRVSISN 93
           ++GK   L C Y T     E + + D  L+T   R V++  + +N++   L+  +     
Sbjct: 250 TEGKHARLSC-YVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ----- 303

Query: 94  NAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI 153
                           +D G Y C+ S   +L G T S V L+V+  P+ P      +  
Sbjct: 304 ----------------SDRGLYTCTAS---NLVGQTYSSV-LVVVREPAVPFKKRLQDLE 343

Query: 154 IGNNIQLTCQSKEGSPTPQYSWKRYNI---LNQEQPLAQPASGQPVSLKNISTDTSGYYI 210
           +      T   +   P+ + +W +       + +  + +  + + ++++N+S D    YI
Sbjct: 344 VREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYI 403

Query: 211 C 211
           C
Sbjct: 404 C 404


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,133,620
Number of Sequences: 37866
Number of extensions: 615707
Number of successful extensions: 5614
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 175
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 3913
Number of HSP's gapped (non-prelim): 1621
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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