BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] (319 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 650 0.0 gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 137 2e-32 gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 128 8e-30 gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 124 1e-28 gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 123 2e-28 gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 117 1e-26 gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 114 1e-25 gi|148664205 endothelial cell adhesion molecule [Homo sapiens] 106 2e-23 gi|8393638 F11 receptor precursor [Homo sapiens] 97 2e-20 gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 89 5e-18 gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 85 7e-17 gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 80 2e-15 gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] 67 2e-11 gi|67188443 CD276 antigen isoform a [Homo sapiens] 65 1e-10 gi|13376852 CD276 antigen isoform b [Homo sapiens] 62 5e-10 gi|6005958 V-set and immunoglobulin domain containing 4 isoform ... 62 7e-10 gi|40255013 carcinoembryonic antigen-related cell adhesion molec... 58 1e-08 gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 58 1e-08 gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 58 1e-08 gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 58 1e-08 gi|221316762 neurotrimin isoform 4 [Homo sapiens] 57 2e-08 gi|221316757 neurotrimin isoform 3 [Homo sapiens] 57 2e-08 gi|115298665 neurotrimin isoform 2 [Homo sapiens] 57 2e-08 gi|7705413 neurotrimin isoform 1 [Homo sapiens] 57 2e-08 gi|66346706 neuronal growth regulator 1 [Homo sapiens] 56 4e-08 gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 56 5e-08 gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 55 6e-08 gi|40254891 hypothetical protein FLJ20674 [Homo sapiens] 55 8e-08 gi|98986445 carcinoembryonic antigen-related cell adhesion molec... 54 1e-07 gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 54 1e-07 >gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] Length = 319 Score = 650 bits (1678), Expect = 0.0 Identities = 319/319 (100%), Positives = 319/319 (100%) Query: 1 MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDK 60 MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDK Sbjct: 1 MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDK 60 Query: 61 LLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS 120 LLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS Sbjct: 61 LLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS 120 Query: 121 LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI 180 LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI Sbjct: 121 LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI 180 Query: 181 LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVG 240 LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVG Sbjct: 181 LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVG 240 Query: 241 IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD 300 IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD Sbjct: 241 IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD 300 Query: 301 YRQEEQRSTGRESPDHLDQ 319 YRQEEQRSTGRESPDHLDQ Sbjct: 301 YRQEEQRSTGRESPDHLDQ 319 >gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo sapiens] Length = 365 Score = 137 bits (344), Expect = 2e-32 Identities = 95/319 (29%), Positives = 161/319 (50%), Gaps = 29/319 (9%) Query: 12 LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQWDKLLLT-----H 65 LC V ++S+ TP++++ ++G++ LPC + S + L I+W L++ Sbjct: 10 LCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEW---LISPADNQK 66 Query: 66 TERVVIWPFSNKNYIHGELY---KNRVSI-SNNAEQSDASITIDQLTMADNGTYECSVSL 121 ++V+I +K I+ + Y K RV SN+ + DASI + L ++D GTY+C V Sbjct: 67 VDQVIILYSGDK--IYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVK- 123 Query: 122 MSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNIL 181 G ++ L+VLV PS C ++G IG++ ++ C+ KEGS QY W++ + Sbjct: 124 --KAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD- 180 Query: 182 NQEQPLAQPA--SGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYV 239 +Q+ P + A + +S+KN S++ SG Y CT N G+ C + + V PS L Sbjct: 181 SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIA 240 Query: 240 GIAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEED 299 G +G + AL +IG+II+CC + E+K + + + E+ P S R Sbjct: 241 GAIIGTLLALALIGLIIFCC----RKKRREEKYEKEVHHDIREDVPPPKSRTSTAR---- 292 Query: 300 DYRQEEQRSTGRESPDHLD 318 Y S G SP +++ Sbjct: 293 SYIGSNHSSLGSMSPSNME 311 >gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo sapiens] Length = 430 Score = 128 bits (321), Expect = 8e-30 Identities = 88/285 (30%), Positives = 141/285 (49%), Gaps = 9/285 (3%) Query: 8 VLWTLCAVRVTVDA-ISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHT 66 +LW C R V A + V ++ ++G+ LPCT+ TS + + W L++ Sbjct: 7 LLWWNCFSRTGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNA 66 Query: 67 ---ERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMS 123 E+V+++ + + + RV + ++ SI I+ ++D GTY+C V+ + Sbjct: 67 NQPEQVILYQ-GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLP 125 Query: 124 DLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY-NILN 182 D+ G L VLVPPS P C I+G IG+++ L C S+EG P P Y W++ N L Sbjct: 126 DIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLK 185 Query: 183 QEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPS-MNVALYVGI 241 Q V+++NIS +SG Y C +SN GT C + + V SP N+ L G Sbjct: 186 LPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAG- 244 Query: 242 AVGVVAALIIIGI-IIYCCCCRGKDDNTEDKEDARPNREAYEEPP 285 A+G A +II I +I + N E++E+ PN ++ P Sbjct: 245 AIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLP 289 >gi|32699028 V-set and immunoglobulin domain containing 1 [Homo sapiens] Length = 387 Score = 124 bits (310), Expect = 1e-28 Identities = 97/340 (28%), Positives = 156/340 (45%), Gaps = 34/340 (10%) Query: 1 MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQWD 59 MV W V L + V + V P + + G +VTL C Y T+ +SRE L IQW Sbjct: 1 MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWS 60 Query: 60 KLLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSV 119 E + I+ + +K+R++ SN + +ASITI + AD+G Y C V Sbjct: 61 FFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSN--DPGNASITISHMQPADSGIYICDV 118 Query: 120 SLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY- 178 + D G + + + VLV PSKP C ++G G+ I L+C S G+P+P Y W + Sbjct: 119 NNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLE 178 Query: 179 --NILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVA 236 +I+ ++ P +G V + N++ GYY CT+ N G C I + P V Sbjct: 179 GRDIVPVKENF-NPTTGILV-IGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP--EVG 234 Query: 237 LYVGIAVG-VVAALIIIGIIIYC---CCCRGKDDNTE--------------DKEDARPNR 278 + VG +G +V A III ++ + + K+ N++ + +A P Sbjct: 235 IIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPRE 294 Query: 279 EAYE---EPPEQLRELSREREEEDDYRQEEQRSTGRESPD 315 +A + P + E + +E DY E + T +P+ Sbjct: 295 DATQLEVTLPSSIHETGPDTIQEPDY---EPKPTQEPAPE 331 >gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo sapiens] Length = 431 Score = 123 bits (309), Expect = 2e-28 Identities = 82/271 (30%), Positives = 135/271 (49%), Gaps = 8/271 (2%) Query: 21 AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHT---ERVVIWPFSNK 77 ++ V ++ ++G+ LPCT+ TS + + W L++ E+V+++ + Sbjct: 22 SLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQ-GGQ 80 Query: 78 NYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLV 137 + + RV + ++ SI I+ ++D GTY+C V+ + D+ G L V Sbjct: 81 MFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTV 140 Query: 138 LVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY-NILNQEQPLAQPASGQPV 196 LVPPS P C I+G IG+++ L C S+EG P P Y W++ N L Q V Sbjct: 141 LVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTV 200 Query: 197 SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPS-MNVALYVGIAVGVVAALIIIGI- 254 +++NIS +SG Y C +SN GT C + + V SP N+ L G A+G A +II I Sbjct: 201 TIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAG-AIGTGAVIIIFCIA 259 Query: 255 IIYCCCCRGKDDNTEDKEDARPNREAYEEPP 285 +I + N E++E+ PN ++ P Sbjct: 260 LILGAFFYWRSKNKEEEEEEIPNEIREDDLP 290 >gi|21361429 V-set and immunoglobulin domain containing 2 [Homo sapiens] Length = 327 Score = 117 bits (294), Expect = 1e-26 Identities = 78/258 (30%), Positives = 121/258 (46%), Gaps = 10/258 (3%) Query: 21 AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTH--TERVVIWPFSNKN 78 A+ V+ P + L GK+ L CTY TS L +W + +E I F+N + Sbjct: 23 AVEVKVPTEPLSTPLGKTAELTCTYSTSVGDSFAL-EWSFVQPGKPISESHPILYFTNGH 81 Query: 79 YIHGELYKNRVSISNNAEQSD-ASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLV 137 RVS+ N A++ + + +D GTY C V+ D N + L V Sbjct: 82 LYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPPDFYTNGLGLINLTV 141 Query: 138 LVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP---LAQPASGQ 194 LVPPS P C G+T +G + L C S EG+P P Y+W R P + SGQ Sbjct: 142 LVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPTPSPGSMVQDEVSGQ 201 Query: 195 PVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGI 254 + L N+S +SG Y C ++N+ G+ C +T++V PS G +GV+ ++++ + Sbjct: 202 LI-LTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ--GRVAGALIGVLLGVLLLSV 258 Query: 255 IIYCCCCRGKDDNTEDKE 272 +C K+ + KE Sbjct: 259 AAFCLVRFQKERGKKPKE 276 >gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] Length = 373 Score = 114 bits (285), Expect = 1e-25 Identities = 85/274 (31%), Positives = 135/274 (49%), Gaps = 19/274 (6%) Query: 26 TPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQWDKLLLTHTE--RVVIWPFSNKNYIHG 82 T ++ R ++ K VTLPC + ++ L I+W LLT E + V+ +S+++ + Sbjct: 19 THTEIKRVAEEK-VTLPCHHQLGLPEKDTLDIEW---LLTDNEGNQKVVITYSSRHVYNN 74 Query: 83 --ELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVP 140 E K RV+ ++N DAS+ I+ L +D G Y C V S V L VLV Sbjct: 75 LTEEQKGRVAFASNFLAGDASLQIEPLKPSDEGRYTCKVKNSGRY---VWSHVILKVLVR 131 Query: 141 PSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS----GQP- 195 PSKP+C +EGE G+++ L C+S G+ Y W+R E P S P Sbjct: 132 PSKPKCELEGELTEGSDLTLQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYNHPG 191 Query: 196 -VSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGI 254 V L+N++ SG Y CT+ NE G + C + V V+ ++ + G G+VA ++I + Sbjct: 192 RVLLQNLTMSYSGLYQCTAGNEAGKESCVVRVTVQY-VQSIGMVAGAVTGIVAGALLIFL 250 Query: 255 IIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQL 288 +++ R + E++E RE E P +L Sbjct: 251 LVWLLIRRKDKERYEEEERPNEIREDAEAPKARL 284 >gi|148664205 endothelial cell adhesion molecule [Homo sapiens] Length = 390 Score = 106 bits (265), Expect = 2e-23 Identities = 84/273 (30%), Positives = 129/273 (47%), Gaps = 34/273 (12%) Query: 22 ISVETPQDVLRASQGKSVTLPCTY--HTSTSSREGLIQWDKLLLTHTERVVIWPFSNK-- 77 + + P + L+A +G V LP Y H SS + W+ V+W F K Sbjct: 31 LQLHLPANRLQAVEGGEVVLPAWYTLHGEVSSSQ---PWEVPF-------VMWFFKQKEK 80 Query: 78 -----NYIHG-ELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKS 131 +YI+G K VS+ + + S+ ++ L D+G Y CSV++ D +G ++ Sbjct: 81 EDQVLSYINGVTTSKPGVSLVYSMPSRNLSLRLEGLQEKDSGPYSCSVNVQ-DKQGKSRG 139 Query: 132 R----VRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPL 187 + L VLVPP+ P C ++G +G N+ L+CQS P QY W R L Q Sbjct: 140 HSIKTLELNVLVPPAPPSCRLQGVPHVGANVTLSCQSPRSKPAVQYQWDRQ--LPSFQTF 197 Query: 188 AQPASG---QPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVG 244 PA +SL N+S+ +G Y+C + NE GT CN+T+ V S A+ G VG Sbjct: 198 FAPALDVIRGSLSLTNLSSSMAGVYVCKAHNEVGTAQCNVTLEV-STGPGAAVVAGAVVG 256 Query: 245 VVAALIIIGIIIYCCCCRGK---DDNTEDKEDA 274 + L ++ ++ RGK + + KEDA Sbjct: 257 TLVGLGLLAGLVLLYHRRGKALEEPANDIKEDA 289 >gi|8393638 F11 receptor precursor [Homo sapiens] Length = 299 Score = 96.7 bits (239), Expect = 2e-20 Identities = 79/291 (27%), Positives = 126/291 (43%), Gaps = 46/291 (15%) Query: 12 LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVI 71 LC++ + +++V + + +R + V L C Y +S R V Sbjct: 21 LCSL--ALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPR-----------------VE 61 Query: 72 WPFSNKNYIHGELYKNRVSISNNAEQS--DASITIDQLTMADNGTYECSVSLMSDLEGNT 129 W F + Y N+++ S + IT +T D GTY C VS + GN+ Sbjct: 62 WKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVS---EEGGNS 118 Query: 130 --KSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP- 186 + +V+L+VLVPPSKP I IGN LTC ++GSP +Y+W + I+ P Sbjct: 119 YGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPK 178 Query: 187 ----------LAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVA 236 + P +G+ V +S +G Y C + N GT + V + + NV Sbjct: 179 STRAFSNSSYVLNPTTGELV-FDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVG 237 Query: 237 LYVGIAVGVVAALIIIGII---IYCCCCRGKDDNTEDKEDARPNREAYEEP 284 + I V+ LI++GI+ I+ RG D T K+ + Y +P Sbjct: 238 V---IVAAVLVTLILLGILVFGIWFAYSRGHFDRT--KKGTSSKKVIYSQP 283 >gi|61966777 V-set and immunoglobulin domain containing 8 [Homo sapiens] Length = 414 Score = 89.0 bits (219), Expect = 5e-18 Identities = 81/286 (28%), Positives = 122/286 (42%), Gaps = 45/286 (15%) Query: 12 LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSR--EGL-IQWDKLLL--THT 66 L AVR+ D Q+VL ++G +V L C Y GL I+W ++ H Sbjct: 19 LSAVRINGDG------QEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNSDPAHH 72 Query: 67 ERVVIWPFSNKNYIHGEL--YKNRVSIS-NNAEQSDASITIDQLTMADNGTYECSVSLMS 123 V + +K HG L + RV + ++ Q DASI + L ++D TYEC V + Sbjct: 73 RENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRVKKTT 132 Query: 124 DLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYN---- 179 +V + V P+ P C EG GN++ L C + GS Y W + + Sbjct: 133 ----MATRKVIVTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYKWAKISGHHY 188 Query: 180 ----------------ILNQE---QPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220 + QE + Q + + LK+IS G Y CT +N G Sbjct: 189 PYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVANNVGYS 248 Query: 221 FCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIY---CCCCRG 263 C + V V S S + + +GI +G + AL + + I+ CCCC G Sbjct: 249 VCVVEVKV-SDSRRIGVIIGIVLGSLLALGCLAVGIWGLVCCCCGG 293 >gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] Length = 298 Score = 85.1 bits (209), Expect = 7e-17 Identities = 71/249 (28%), Positives = 113/249 (45%), Gaps = 36/249 (14%) Query: 23 SVETPQDVLRASQGKSVTLPC-TYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIH 81 S Q V+ A + + L C T + SSR ++W KL R V + + + + Sbjct: 30 SAPKDQQVVTAVEYQEAILACKTPKKTVSSR---LEWKKL-----GRSVSFVYYQQT-LQ 80 Query: 82 GELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKS-RVRLLVLVP 140 G+ +KNR AE D +I I +T +D G Y C VS S+ N + V L VLV Sbjct: 81 GD-FKNR------AEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVA 133 Query: 141 PSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKN 200 P+ P C + + G ++L CQ KEG+P P+Y+W + I E P S N Sbjct: 134 PAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMN 193 Query: 201 ISTDT----------SGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALI 250 T T +G Y C + N G + C ++ +N++ G++AA++ Sbjct: 194 TKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCP-GKRMQVDDLNIS-------GIIAAVV 245 Query: 251 IIGIIIYCC 259 ++ ++I C Sbjct: 246 VVALVISVC 254 >gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] Length = 355 Score = 80.1 bits (196), Expect = 2e-15 Identities = 78/296 (26%), Positives = 122/296 (41%), Gaps = 29/296 (9%) Query: 19 VDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKN 78 + A+++++ + +SV L C T + + + I+W K+ T V F NK Sbjct: 74 IGAVNLKSSNRTPVVQEFESVELSCII-TDSQTSDPRIEWKKIQDEQTTYVF---FDNK- 128 Query: 79 YIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL 138 I G+L R I S+ I +T D+ Y C V +D + + + L V Sbjct: 129 -IQGDL-AGRAEILGKT-----SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQ 181 Query: 139 VPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSL 198 V P P C + +G L CQ EG P P YSW R ++ A P Sbjct: 182 VKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFH 241 Query: 199 KNIST----------DTSGYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAA 248 N T D SG Y C +SN+ G+ C + +N+ +G + V+A Sbjct: 242 LNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCE-EQEMEVYDLNIGGIIGGVLVVLAV 300 Query: 249 LIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDDYRQE 304 L +I + I C RG N +K+D E+Y+ P + +EE D+R + Sbjct: 301 LALITLGICCAYRRGYFIN--NKQDG----ESYKNPGKPDGVNYIRTDEEGDFRHK 350 >gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] Length = 416 Score = 67.0 bits (162), Expect = 2e-11 Identities = 71/309 (22%), Positives = 136/309 (44%), Gaps = 35/309 (11%) Query: 4 KMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLL 63 ++ P ++ L ++ +++ +P ++ + GKS L Y +STSS +++W Sbjct: 16 RLAPFVYLLLIQTDPLEGVNITSPVRLIHGTVGKSALLSVQY-SSTSSDRPVVKWQ---- 70 Query: 64 THTERVVIWPFSNKNYIHGEL---YKNRVSISNNAEQSDASITIDQLTMADNGTYECSVS 120 ++ V S + G L Y++R+ + N S+ + L +AD GTYE +S Sbjct: 71 LKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENG-----SLLLSDLQLADEGTYEVEIS 125 Query: 121 LMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI--IGNNIQLTCQSKEGSPTPQYSWKRY 178 + D K+ + L V VP S+P+ + T+ + L C S E P Y+W + Sbjct: 126 ITDDTFTGEKT-INLTVDVPISRPQVLVASTTVLELSEAFTLNC-SHENGTKPSYTWLKD 183 Query: 179 N--ILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSN--EEGTQF-CNITVAVRSPSM 233 +LN + L P + +++ + + Y C N +G ITV RS Sbjct: 184 GKPLLNDSRMLLSP-DQKVLTITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRS--- 239 Query: 234 NVALYVGIAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLR---- 289 +LY+ ++ G + L+ ++ C C + K + + + E ++ ++L+ Sbjct: 240 --SLYIILSTGGIFLLV---TLVTVCACWKPSKRKQKKLEKQNSLEYMDQNDDRLKPEAD 294 Query: 290 ELSREREEE 298 L R E+E Sbjct: 295 TLPRSGEQE 303 >gi|67188443 CD276 antigen isoform a [Homo sapiens] Length = 534 Score = 64.7 bits (156), Expect = 1e-10 Identities = 77/309 (24%), Positives = 132/309 (42%), Gaps = 34/309 (11%) Query: 11 TLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLL-LTHTERV 69 T+ R A+ V+ P+D + A G TL C++ S L Q + + LT T+++ Sbjct: 236 TITPQRSPTGAVEVQVPEDPVVALVGTDATLRCSF--SPEPGFSLAQLNLIWQLTDTKQL 293 Query: 70 VIWPFSNKNYIHGELYKNRVSISNNA-EQSDASITIDQLTMADNGTYECSVSLMSDLEGN 128 V ++ G Y NR ++ + Q +AS+ + ++ +AD G++ C VS + Sbjct: 294 VHSFTEGRD--QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS----IRDF 347 Query: 129 TKSRVRLLVLVPPSKPECGIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP 186 + V L V P SKP +E + G+ + +TC S G P + W+ Q P Sbjct: 348 GSAAVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD----GQGVP 403 Query: 187 L------AQPASGQPV----SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNV- 235 L +Q A+ Q + S+ + +G Y C N Q + +V + M Sbjct: 404 LTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFP 463 Query: 236 --ALY--VGIAVGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLREL 291 AL+ VG++V ++A L+ + + C + K E+ A E L+ L Sbjct: 464 PEALWVTVGLSVCLIALLVALAFV---CWRKIKQSCEEENAGAEDQDGEGEGSKTALQPL 520 Query: 292 SREREEEDD 300 +EDD Sbjct: 521 KHSDSKEDD 529 Score = 55.5 bits (132), Expect = 6e-08 Identities = 59/235 (25%), Positives = 104/235 (44%), Gaps = 27/235 (11%) Query: 21 AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYI 80 A+ V+ P+D + A G TL C++ S L Q + + + ++ F+ + Sbjct: 28 ALEVQVPEDPVVALVGTDATLCCSF--SPEPGFSLAQLNLIWQLTDTKQLVHSFA-EGQD 84 Query: 81 HGELYKNRVSISNNA-EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLV 139 G Y NR ++ + Q +AS+ + ++ +AD G++ C VS + + V L V Sbjct: 85 QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS----IRDFGSAAVSLQVAA 140 Query: 140 PPSKPECGIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPL------AQPA 191 P SKP +E + G+ + +TC S +G P + W+ Q PL +Q A Sbjct: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD----GQGVPLTGNVTTSQMA 196 Query: 192 SGQPV----SLKNISTDTSGYYICTSSNEEGTQFCNITVAV---RSPSMNVALYV 239 + Q + S+ + +G Y C N Q + +V + RSP+ V + V Sbjct: 197 NEQGLFDVHSILRVVLGANGTYSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQV 251 >gi|13376852 CD276 antigen isoform b [Homo sapiens] Length = 316 Score = 62.4 bits (150), Expect = 5e-10 Identities = 72/298 (24%), Positives = 126/298 (42%), Gaps = 32/298 (10%) Query: 21 AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYI 80 A+ V+ P+D + A G TL C++ S L Q + + + ++ F+ + Sbjct: 28 ALEVQVPEDPVVALVGTDATLCCSF--SPEPGFSLAQLNLIWQLTDTKQLVHSFA-EGQD 84 Query: 81 HGELYKNRVSISNNA-EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLV 139 G Y NR ++ + Q +AS+ + ++ +AD G++ C VS + + V L V Sbjct: 85 QGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS----IRDFGSAAVSLQVAA 140 Query: 140 PPSKPECGIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPL------AQPA 191 P SKP +E + G+ + +TC S G P + W+ Q PL +Q A Sbjct: 141 PYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD----GQGVPLTGNVTTSQMA 196 Query: 192 SGQPV----SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNV---ALY--VGIA 242 + Q + S+ + +G Y C N Q + +V + M AL+ VG++ Sbjct: 197 NEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWVTVGLS 256 Query: 243 VGVVAALIIIGIIIYCCCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDD 300 V ++A L+ + + C + K E+ A E L+ L +EDD Sbjct: 257 VCLIALLVALAFV---CWRKIKQSCEEENAGAEDQDGEGEGSKTALQPLKHSDSKEDD 311 >gi|6005958 V-set and immunoglobulin domain containing 4 isoform 1 [Homo sapiens] Length = 399 Score = 62.0 bits (149), Expect = 7e-10 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 20/225 (8%) Query: 8 VLWTLCAVRVTVDAIS---VETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLT 64 +L L +TVD +E P+ V +G V LPCTY + L++W L+ Sbjct: 4 LLGLLLLGHLTVDTYGRPILEVPESVTGPWKG-DVNLPCTYDPLQGYTQVLVKW--LVQR 60 Query: 65 HTERVVIW-PFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMS 123 ++ V I+ S+ ++I Y+ R+ +S+ D S+ + L M D Y C V+ + Sbjct: 61 GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKV-PGDVSLQLSTLEMDDRSHYTCEVTWQT 119 Query: 124 DLEGN-------TKSRVRLLVLVPPSKPECGIEGETI-IGNNIQLTCQSKEGSPTPQYSW 175 +GN T+ RV+ L + P+ G T+ G I L CQ++ GSP Y W Sbjct: 120 P-DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQAR-GSPPISYIW 177 Query: 176 KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220 + NQE + A+ + K SG Y CT+ + G++ Sbjct: 178 YKQQTNNQEP--IKVATLSTLLFKPAVIADSGSYFCTAKGQVGSE 220 >gi|40255013 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) [Homo sapiens] Length = 344 Score = 58.2 bits (139), Expect = 1e-08 Identities = 47/169 (27%), Positives = 76/169 (44%), Gaps = 18/169 (10%) Query: 91 ISNNAEQSDASITIDQLTMADN--GTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG- 147 +S + S+ ++T+ L++ N G+YEC + + N V L VL P P Sbjct: 187 VSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQ--NPASANRSDPVTLNVLYGPDGPTISP 244 Query: 148 IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSG 207 + G N+ L+C + P QYSW Q S Q + + NI+ + SG Sbjct: 245 SKANYRPGENLNLSCHAASNPPA-QYSWFINGTFQQ--------STQELFIPNITVNNSG 295 Query: 208 YYICTSSNE----EGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIII 252 Y+C + N T ITV+ +P ++ VGI +GV+A + +I Sbjct: 296 SYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI 344 >gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] Length = 1215 Score = 57.8 bits (138), Expect = 1e-08 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%) Query: 95 AEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII 154 A+ +D S+ I + D G Y+C + S+ G T++ V LLV P Sbjct: 448 AQLADLSLEISGIIPTDGGRYQC---VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQ 504 Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSS 214 G ++++C S G PTP SW R + QE + + ++ ++ + +G Y C ++ Sbjct: 505 GVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 563 Query: 215 NEEGTQFCNITVAVRSPSMNVAL--YVGIAVGVVAALI 250 NE GT +T+ P A+ V +AVG A L+ Sbjct: 564 NEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 601 Score = 43.9 bits (102), Expect = 2e-04 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 5/128 (3%) Query: 92 SNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGE 151 S ++ ++D S+ +D+ G Y C + ++ G+ V L+V VPP Sbjct: 813 SRHSIRADGSLHLDRALQEHAGRYSC---VATNTAGSQHRDVELVVQVPPRIHPTATHHI 869 Query: 152 TIIGNNIQLTCQSKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYI 210 T G L C + G P P +W K N L P + + + S +G Y+ Sbjct: 870 TNEGVPASLPCVAS-GVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYV 928 Query: 211 CTSSNEEG 218 CT++N G Sbjct: 929 CTATNTVG 936 Score = 37.0 bits (84), Expect = 0.023 Identities = 32/131 (24%), Positives = 54/131 (41%), Gaps = 16/131 (12%) Query: 99 DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI----- 153 + ++ I Q + D G Y C+ + + G + +RL V P G + Sbjct: 911 EGTLLIAQPSAQDAGAYVCTAT---NTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVT 967 Query: 154 --IGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQP---VSLKNISTDTSGY 208 G + L C++K GSP P +W + + P+ P + L + SG+ Sbjct: 968 AKAGEEVTLDCEAK-GSPPPLVTWTKDS--RPVPPITNRYGLLPSGSLRLAQVQVGDSGH 1024 Query: 209 YICTSSNEEGT 219 Y CT+SN G+ Sbjct: 1025 YECTASNPAGS 1035 Score = 35.4 bits (80), Expect = 0.068 Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 20/149 (13%) Query: 96 EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIG 155 E ++S I + + A+ GTYEC+ + G +++ +++V PP + G Sbjct: 358 ESGNSSWEILRASKAEEGTYECTAVSRA---GTGRAKAQIVVTDPPPQLVPAPNVTVSPG 414 Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGY------ 208 L+C+ +P YN+ PAS G+ L ++S + SG Sbjct: 415 ETAVLSCRVLGEAP--------YNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGG 466 Query: 209 -YICTSSNEEGTQFCNITVAVR-SPSMNV 235 Y C +SN G ++ + VR +P +++ Sbjct: 467 RYQCVASNANGVTRASVWLLVREAPQVSI 495 Score = 35.0 bits (79), Expect = 0.088 Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 18/148 (12%) Query: 93 NNAEQSDASITI-DQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL--VPPSKPECGIE 149 + + Q D+ + + + D Y C ++ G ++ RL+V PP Sbjct: 720 SRSRQPDSGVLFFESVAPEDQAPYVCEAR---NVFGKVQAEARLIVTGHAPPQIASSAPT 776 Query: 150 GETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVS------LKNIST 203 + G + L C G P P+ W L +PL P S + L Sbjct: 777 VRVLEGQPVSLPCIVLAGRPLPERHW-----LKDGRPLP-PGSRHSIRADGSLHLDRALQ 830 Query: 204 DTSGYYICTSSNEEGTQFCNITVAVRSP 231 + +G Y C ++N G+Q ++ + V+ P Sbjct: 831 EHAGRYSCVATNTAGSQHRDVELVVQVP 858 >gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] Length = 5065 Score = 57.8 bits (138), Expect = 1e-08 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%) Query: 95 AEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII 154 A+ +D S+ I + D G Y+C + S+ G T++ V LLV P Sbjct: 565 AQLADLSLEISGIIPTDGGRYQC---VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQ 621 Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSS 214 G ++++C S G PTP SW R + QE + + ++ ++ + +G Y C ++ Sbjct: 622 GVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 680 Query: 215 NEEGTQFCNITVAVRSPSMNVAL--YVGIAVGVVAALI 250 NE GT +T+ P A+ V +AVG A L+ Sbjct: 681 NEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 718 Score = 52.8 bits (125), Expect = 4e-07 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 9/131 (6%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160 S+ + Q+ + D+G YEC+ S + G+ R L V VPP + ++G + L Sbjct: 1083 SLRLAQVQVGDSGHYECTAS---NPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDL 1139 Query: 161 TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220 C + EG+P PQ SW + ++ Q + V I T +G Y C +SN G Sbjct: 1140 NCVA-EGNPEPQLSWSKDGVVLQGR-----GPQGSVHFAAIRTSDAGRYRCEASNSAGVD 1193 Query: 221 FCNITVAVRSP 231 + + V P Sbjct: 1194 AWEVELRVLEP 1204 Score = 50.4 bits (119), Expect = 2e-06 Identities = 39/142 (27%), Positives = 64/142 (45%), Gaps = 7/142 (4%) Query: 90 SISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIE 149 S + E + + ++ A +G Y C + S G + + V VPP Sbjct: 1640 SNESRLETDGSVLRLESPGEASSGLYSC---VASSPAGEAVLQYSVEVQVPPQLLVAEGL 1696 Query: 150 GE--TIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTS 206 G+ TI+G ++L CQ+ GSP P W + +E Q AS G + + ++ D S Sbjct: 1697 GQVTTIVGQPLELPCQAS-GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHS 1755 Query: 207 GYYICTSSNEEGTQFCNITVAV 228 G + C ++NE GT + V+V Sbjct: 1756 GLFACQATNEAGTAGAEVEVSV 1777 Score = 48.5 bits (114), Expect = 8e-06 Identities = 40/156 (25%), Positives = 64/156 (41%), Gaps = 32/156 (20%) Query: 99 DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGET--IIGN 156 + S+ + ++ AD+G YEC + + G+T R +L+V VPPS E G + + G Sbjct: 1260 EGSLFLASVSPADSGDYECQAT---NEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQ 1316 Query: 157 NIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS---------------------GQP 195 ++ L C + G P P+ W L Q + P GQ Sbjct: 1317 SLTLECDAN-GFPVPEIVW-----LKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS 1370 Query: 196 VSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSP 231 + I SG Y C + N+ GT + + V +P Sbjct: 1371 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP 1406 Score = 48.5 bits (114), Expect = 8e-06 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 5/131 (3%) Query: 102 ITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLT 161 + I+++ + D G Y C+ + +L G +K V L VLVPP+ + + ++ L Sbjct: 1850 LQIEKVDLRDEGIYTCAAT---NLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLE 1906 Query: 162 CQSKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220 C + G P P SW K + ++ + G+ + ++ +G Y C +SN G+ Sbjct: 1907 CLA-SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGST 1965 Query: 221 FCNITVAVRSP 231 + V P Sbjct: 1966 ELRYGLRVNVP 1976 Score = 46.2 bits (108), Expect = 4e-05 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 8/135 (5%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI--IGNNI 158 S+ ++ D+G Y C + G + LLVL PPS G E + G ++ Sbjct: 1370 SLHFPRIQEGDSGLYSCRAENQA---GTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADV 1426 Query: 159 QLTCQSKEGSPTPQYSWK--RYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNE 216 +L C + G PTPQ W R +L L GQ + + G Y C + + Sbjct: 1427 ELQCWTS-GVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSP 1485 Query: 217 EGTQFCNITVAVRSP 231 G Q + + V +P Sbjct: 1486 AGQQARDFQLRVHAP 1500 Score = 45.1 bits (105), Expect = 9e-05 Identities = 41/144 (28%), Positives = 62/144 (43%), Gaps = 19/144 (13%) Query: 107 LTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII----GNNIQLTC 162 L + D G Y C L G + R+ V PP+ G G + + L C Sbjct: 3549 LRVRDAGLYTC---LAESPAGAIEKSFRVRVQAPPNI--VGPRGPRFVVGLAPGQLVLEC 3603 Query: 163 QSKEGSPTPQYSWKRYNILNQEQPLAQ-PASGQPVSLKNISTDTSGYYICTSSNEEGTQF 221 S E P P+ +W R I+ QE Q P G+ + L+ +ST SG Y CT+ N G+ Sbjct: 3604 -SVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTS 3662 Query: 222 CNITVAVRS--------PSMNVAL 237 V + + P++NV++ Sbjct: 3663 VAFRVEIHTVPTIRSGPPAVNVSV 3686 Score = 43.9 bits (102), Expect = 2e-04 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 5/128 (3%) Query: 92 SNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGE 151 S ++ ++D S+ +D+ G Y C + ++ G+ V L+V VPP Sbjct: 930 SRHSIRADGSLHLDRALQEHAGRYSC---VATNTAGSQHRDVELVVQVPPRIHPTATHHI 986 Query: 152 TIIGNNIQLTCQSKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYI 210 T G L C + G P P +W K N L P + + + S +G Y+ Sbjct: 987 TNEGVPASLPCVAS-GVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYV 1045 Query: 211 CTSSNEEG 218 CT++N G Sbjct: 1046 CTATNTVG 1053 Score = 42.7 bits (99), Expect = 4e-04 Identities = 37/145 (25%), Positives = 61/145 (42%), Gaps = 11/145 (7%) Query: 110 ADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEG---ETIIGNNIQLTCQSKE 166 +D G Y C S + G + RL V VPP+ G + + G + L C ++ Sbjct: 1566 SDAGVYTCKAS---NAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVAR- 1621 Query: 167 GSPTPQYSWKRYNILNQEQPLAQ-PASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNIT 225 G P+P SW + E ++ G + L++ +SG Y C +S+ G + Sbjct: 1622 GHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYS 1681 Query: 226 VAVRSPSMNVALYVGIAVGVVAALI 250 V V+ P L V +G V ++ Sbjct: 1682 VEVQVPPQ---LLVAEGLGQVTTIV 1703 Score = 42.4 bits (98), Expect = 6e-04 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%) Query: 111 DNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPT 170 D G Y C + + G+ + RL+V VPP + T G++ L C+++ GSP Sbjct: 4011 DAGNYLC---IAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKAR-GSPE 4066 Query: 171 PQYSWKRYN--ILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEG 218 P +W + + E SG+ + +KN+ +G Y CT+ N G Sbjct: 4067 PNITWDKDGQPVSGAEGKFTIQPSGE-LLVKNLEGQDAGTYTCTAENAVG 4115 Score = 42.0 bits (97), Expect = 7e-04 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 20/139 (14%) Query: 99 DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII---G 155 + S+TI + D G Y+C +++ E +V +LVL S P +E + + G Sbjct: 4270 NGSLTIHRTERDDAGRYQC----LAENEMGVAKKVVILVL--QSAPVFQVEPQDMTVRSG 4323 Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVS-----LKNISTDTSGYYI 210 +++ L CQ+ G PTP W L QPL + + L+N+ T +G Y Sbjct: 4324 DDVALRCQAT-GEPTPTIEW-----LQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYD 4377 Query: 211 CTSSNEEGTQFCNITVAVR 229 C + N G+ + VR Sbjct: 4378 CVAHNLLGSATARAFLVVR 4396 Score = 41.6 bits (96), Expect = 0.001 Identities = 51/230 (22%), Positives = 88/230 (38%), Gaps = 44/230 (19%) Query: 12 LCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQW--DKLLLTHTERV 69 L +RV V + + A SV+LPC H + + W D L+ E V Sbjct: 2928 LFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPE---VTWYKDSQALSLGEEV 2984 Query: 70 VIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNT 129 + P ++ ++ + + ++D+G Y C + G Sbjct: 2985 FLLPGTH------------------------TLQLGRARLSDSGMYTCEAL---NAAGRD 3017 Query: 130 KSRVRLLVLVPPSKPEC--GIEGETII--GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQ 185 + V+L VLVPP+ + G + ++ G+ L+C++ + P P +W + Q Sbjct: 3018 QKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCET-DALPEPTVTWYKDG---QPL 3073 Query: 186 PLAQPAS----GQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSP 231 LAQ GQ + ++ G Y C SN G T+ V+ P Sbjct: 3074 VLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP 3123 Score = 41.2 bits (95), Expect = 0.001 Identities = 38/142 (26%), Positives = 58/142 (40%), Gaps = 22/142 (15%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPS-----KPECGIEGETIIG 155 S+ +++ A G Y C + +L G + + L VLVPP P I + Sbjct: 2313 SLHVERAQAAHTGRYSC---VAENLAGRAERKFELSVLVPPELIGDLDPLTNITAA--LH 2367 Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQP------ASGQPVSLKNISTDTSGYY 209 + + L C++ G P P W R E+P++ A G + + SG Y Sbjct: 2368 SPLTLLCEAM-GIPPPAIRWFR-----GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLY 2421 Query: 210 ICTSSNEEGTQFCNITVAVRSP 231 C +SNE G N +V V P Sbjct: 2422 SCLASNEAGEARRNFSVEVLVP 2443 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/119 (21%), Positives = 53/119 (44%), Gaps = 5/119 (4%) Query: 102 ITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLT 161 + + L+ AD+G Y C+ + G+T R+ + P+ + L Sbjct: 3637 LQLQALSTADSGDYSCTAR---NAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLP 3693 Query: 162 CQSKEGSPTPQYSWKRYNI-LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGT 219 CQ+ +G P P SW++ + L+ P + + ++ + +G+Y+C +SN G+ Sbjct: 3694 CQA-DGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGS 3751 Score = 38.1 bits (87), Expect = 0.010 Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 7/113 (6%) Query: 109 MADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNN--IQLTCQSKE 166 + D G Y+C + G +L V PP+ GE + + +QL C+++ Sbjct: 1472 VGDEGRYQC---VAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEAR- 1527 Query: 167 GSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEG 218 G PTP +W K +L + G+ + L + +G Y C +SN G Sbjct: 1528 GVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 1580 Score = 37.4 bits (85), Expect = 0.018 Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 14/158 (8%) Query: 107 LTMADN-GTYECSVSLMSDLEGNTKSRVRLLVLVPP---SKPECGIEGETI-IGNNIQLT 161 L A+N G Y C S + G LLVL PP E +E T+ + + L Sbjct: 2810 LVRAENAGRYSCKAS---NEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ 2866 Query: 162 CQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGYYICTSSNEEGTQ 220 C + G+P P SW + + P Q GQ + + + Y+C + N+ G+ Sbjct: 2867 CPAL-GNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSA 2925 Query: 221 FCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIYC 258 T+ V+ P G+ + V A++ + + C Sbjct: 2926 EKLFTLRVQVPPR----IAGLDLEQVTAILNSSVSLPC 2959 Score = 36.6 bits (83), Expect = 0.030 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 12/131 (9%) Query: 111 DNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKP------ECGI-EGETIIGNNIQLTCQ 163 D G Y C V+ ++L G + VL+PPS E G+ E +T + + + L C+ Sbjct: 2606 DAGQYTCVVT--NEL-GEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECE 2662 Query: 164 SKEGSPTPQYSW-KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFC 222 S P P W K + L G+ + ++ SG Y+C ++N G Sbjct: 2663 SW-AVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQ 2721 Query: 223 NITVAVRSPSM 233 + V ++ P M Sbjct: 2722 DFNVLIQVPPM 2732 Score = 36.6 bits (83), Expect = 0.030 Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 8/135 (5%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII---GNN 157 S+ + L +D G Y C + + G + VLVPP+ + T++ G Sbjct: 3274 SLVLKGLRASDAGAYTC---VAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGEL 3330 Query: 158 IQLTCQSKEGSPTPQYSWKRYNI-LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNE 216 + + C + GSP SW + + L Q SG + + + +G + C +++ Sbjct: 3331 VTMVCPVR-GSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASP 3389 Query: 217 EGTQFCNITVAVRSP 231 G N T+ V+ P Sbjct: 3390 AGVADRNFTLQVQVP 3404 Score = 35.8 bits (81), Expect = 0.052 Identities = 32/155 (20%), Positives = 59/155 (38%), Gaps = 33/155 (21%) Query: 102 ITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG-------------- 147 + I ++D+G Y C + +++ G +L+ VPP + G Sbjct: 2695 LQIQPTQVSDSGRYLC---VATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEE 2751 Query: 148 -----IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQP------ASGQPV 196 E I+ NN P P +W R ++QPL+ G+ + Sbjct: 2752 ARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYR-----EDQPLSAGDEVSVLQGGRVL 2806 Query: 197 SLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSP 231 + + + +G Y C +SNE G + + + V +P Sbjct: 2807 QIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTP 2841 Score = 35.4 bits (80), Expect = 0.068 Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 20/149 (13%) Query: 96 EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIG 155 E ++S I + + A+ GTYEC+ + G +++ +++V PP + G Sbjct: 475 ESGNSSWEILRASKAEEGTYECTAVSRA---GTGRAKAQIVVTDPPPQLVPAPNVTVSPG 531 Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGY------ 208 L+C+ +P YN+ PAS G+ L ++S + SG Sbjct: 532 ETAVLSCRVLGEAP--------YNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGG 583 Query: 209 -YICTSSNEEGTQFCNITVAVR-SPSMNV 235 Y C +SN G ++ + VR +P +++ Sbjct: 584 RYQCVASNANGVTRASVWLLVREAPQVSI 612 Score = 35.4 bits (80), Expect = 0.068 Identities = 29/136 (21%), Positives = 53/136 (38%), Gaps = 17/136 (12%) Query: 91 ISNNAEQSDASITIDQLTMA--DNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148 ++ + D T+ + ++ D+GTY C N R + + V + + Sbjct: 4169 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAE-------NRVGRTQAVSFVHVKEAPV-L 4220 Query: 149 EGETI------IGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNIS 202 +GE +G +IQL C + G P P W + + + L +++ Sbjct: 4221 QGEAFSYLVEPVGGSIQLDCVVR-GDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTE 4279 Query: 203 TDTSGYYICTSSNEEG 218 D +G Y C + NE G Sbjct: 4280 RDDAGRYQCLAENEMG 4295 Score = 35.0 bits (79), Expect = 0.088 Identities = 32/148 (21%), Positives = 57/148 (38%), Gaps = 18/148 (12%) Query: 93 NNAEQSDASITI-DQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL--VPPSKPECGIE 149 + + Q D+ + + + D Y C ++ G ++ RL+V PP Sbjct: 837 SRSRQPDSGVLFFESVAPEDQAPYVCEAR---NVFGKVQAEARLIVTGHAPPQIASSAPT 893 Query: 150 GETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVS------LKNIST 203 + G + L C G P P+ W L +PL P S + L Sbjct: 894 VRVLEGQPVSLPCIVLAGRPLPERHW-----LKDGRPLP-PGSRHSIRADGSLHLDRALQ 947 Query: 204 DTSGYYICTSSNEEGTQFCNITVAVRSP 231 + +G Y C ++N G+Q ++ + V+ P Sbjct: 948 EHAGRYSCVATNTAGSQHRDVELVVQVP 975 Score = 34.3 bits (77), Expect = 0.15 Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 5/118 (4%) Query: 102 ITIDQLTMADNGTYEC-SVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160 +T+ +D+G Y C +VS + G + V L V +PPS + + ++ L Sbjct: 2035 LTLASARASDSGRYSCVAVSAV----GEDRQDVVLQVHMPPSILGEELNVSVVANESVAL 2090 Query: 161 TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEG 218 CQS P WK L + A + + +G+Y C + N+ G Sbjct: 2091 ECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEALNQAG 2148 Score = 33.9 bits (76), Expect = 0.20 Identities = 27/131 (20%), Positives = 48/131 (36%), Gaps = 4/131 (3%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160 ++ I Q G Y CS + G V L V P + + L Sbjct: 3911 ALEIGQALPIHAGRYTCSAR---NSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLL 3967 Query: 161 TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220 C++ G P P +W++ + Q G + + + S + +G Y+C + N G+ Sbjct: 3968 PCEAS-GIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSA 4026 Query: 221 FCNITVAVRSP 231 + V+ P Sbjct: 4027 MGKTRLVVQVP 4037 Score = 33.1 bits (74), Expect = 0.34 Identities = 30/132 (22%), Positives = 51/132 (38%), Gaps = 10/132 (7%) Query: 106 QLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPS-----KPECGIEGETIIGNNIQL 160 Q ++ G Y C + ++ G +L VL+ P+ + E + N I L Sbjct: 2505 QANLSSAGHYSC---IAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPISL 2561 Query: 161 TCQSKEGSPTPQYSWKRYNILNQEQPLAQPASG-QPVSLKNISTDTSGYYICTSSNEEGT 219 C++ P+P +W + + Q G + + N + +G Y C +NE G Sbjct: 2562 ICEAL-AFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGE 2620 Query: 220 QFCNITVAVRSP 231 N V V P Sbjct: 2621 AVKNYHVEVLIP 2632 >gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo sapiens] Length = 790 Score = 57.8 bits (138), Expect = 1e-08 Identities = 44/158 (27%), Positives = 73/158 (46%), Gaps = 6/158 (3%) Query: 95 AEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETII 154 A+ +D S+ I + D G Y+C + S+ G T++ V LLV P Sbjct: 564 AQLADLSLEISGIIPTDGGRYQC---VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQ 620 Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSS 214 G ++++C S G PTP SW R + QE + + ++ ++ + +G Y C ++ Sbjct: 621 GVEVKVSC-SASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 679 Query: 215 NEEGTQFCNITVAVRSPSMNVAL--YVGIAVGVVAALI 250 NE GT +T+ P A+ V +AVG A L+ Sbjct: 680 NEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 717 Score = 35.4 bits (80), Expect = 0.068 Identities = 35/149 (23%), Positives = 65/149 (43%), Gaps = 20/149 (13%) Query: 96 EQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIG 155 E ++S I + + A+ GTYEC+ + G +++ +++V PP + G Sbjct: 474 ESGNSSWEILRASKAEEGTYECTAVSRA---GTGRAKAQIVVTDPPPQLVPAPNVTVSPG 530 Query: 156 NNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS-GQPVSLKNISTDTSGY------ 208 L+C+ +P YN+ PAS G+ L ++S + SG Sbjct: 531 ETAVLSCRVLGEAP--------YNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGG 582 Query: 209 -YICTSSNEEGTQFCNITVAVR-SPSMNV 235 Y C +SN G ++ + VR +P +++ Sbjct: 583 RYQCVASNANGVTRASVWLLVREAPQVSI 611 >gi|221316762 neurotrimin isoform 4 [Homo sapiens] Length = 316 Score = 57.4 bits (137), Expect = 2e-08 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%) Query: 29 DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88 D + QG+S TL CT + R + +L ++ + P R Sbjct: 43 DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87 Query: 89 VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148 V + +N Q+ SI I + + D G Y CSV +D T SRV L+V V P E Sbjct: 88 VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143 Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208 + GNNI LTC + G P P +W+ + + + + + + ++ I+ + SG Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198 Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244 Y C++SN+ + V V P ++ A G+ VG Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%) Query: 99 DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158 D + I +T +G YECS S +D+ RV++ V PP E G + G Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239 Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214 L C++ P+ ++ W + + E +P K N+S G Y C +S Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298 Query: 215 NEEG 218 N+ G Sbjct: 299 NKLG 302 >gi|221316757 neurotrimin isoform 3 [Homo sapiens] Length = 355 Score = 57.4 bits (137), Expect = 2e-08 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%) Query: 29 DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88 D + QG+S TL CT + R + +L ++ + P R Sbjct: 43 DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87 Query: 89 VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148 V + +N Q+ SI I + + D G Y CSV +D T SRV L+V V P E Sbjct: 88 VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143 Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208 + GNNI LTC + G P P +W+ + + + + + + ++ I+ + SG Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198 Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244 Y C++SN+ + V V P ++ A G+ VG Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%) Query: 99 DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158 D + I +T +G YECS S +D+ RV++ V PP E G + G Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239 Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214 L C++ P+ ++ W + + E +P K N+S G Y C +S Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298 Query: 215 NEEG 218 N+ G Sbjct: 299 NKLG 302 >gi|115298665 neurotrimin isoform 2 [Homo sapiens] Length = 344 Score = 57.4 bits (137), Expect = 2e-08 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%) Query: 29 DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88 D + QG+S TL CT + R + +L ++ + P R Sbjct: 43 DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87 Query: 89 VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148 V + +N Q+ SI I + + D G Y CSV +D T SRV L+V V P E Sbjct: 88 VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143 Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208 + GNNI LTC + G P P +W+ + + + + + + ++ I+ + SG Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198 Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244 Y C++SN+ + V V P ++ A G+ VG Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%) Query: 99 DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158 D + I +T +G YECS S +D+ RV++ V PP E G + G Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239 Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214 L C++ P+ ++ W + + E +P K N+S G Y C +S Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298 Query: 215 NEEG 218 N+ G Sbjct: 299 NKLG 302 >gi|7705413 neurotrimin isoform 1 [Homo sapiens] Length = 344 Score = 57.4 bits (137), Expect = 2e-08 Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 26/218 (11%) Query: 29 DVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNR 88 D + QG+S TL CT + R + +L ++ + P R Sbjct: 43 DNVTVRQGESATLRCTIDNRVT-RVAWLNRSTILYAGNDKWCLDP--------------R 87 Query: 89 VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148 V + +N Q+ SI I + + D G Y CSV +D T SRV L+V V P E Sbjct: 88 VVLLSNT-QTQYSIEIQNVDVYDEGPYTCSVQ--TDNHPKT-SRVHLIVQVSPKIVEISS 143 Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGY 208 + GNNI LTC + G P P +W+ + + + + + + ++ I+ + SG Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHIS----PKAVGFVSEDEYLEIQGITREQSGD 198 Query: 209 YICTSSNEEGTQFC-NITVAVR-SPSMNVALYVGIAVG 244 Y C++SN+ + V V P ++ A G+ VG Sbjct: 199 YECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVG 236 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 8/124 (6%) Query: 99 DASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNI 158 D + I +T +G YECS S +D+ RV++ V PP E G + G Sbjct: 183 DEYLEIQGITREQSGDYECSAS--NDVAAPVVRRVKVTVNYPPYISEAKGTGVPV-GQKG 239 Query: 159 QLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLK----NISTDTSGYYICTSS 214 L C++ P+ ++ W + + E +P K N+S G Y C +S Sbjct: 240 TLQCEAS-AVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVAS 298 Query: 215 NEEG 218 N+ G Sbjct: 299 NKLG 302 >gi|66346706 neuronal growth regulator 1 [Homo sapiens] Length = 354 Score = 56.2 bits (134), Expect = 4e-08 Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 12/130 (9%) Query: 88 RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147 RVSIS + D S+ I + + D+G Y CSV +V L V VPP + Sbjct: 90 RVSIST-LNKRDYSLQIQNVDVTDDGPYTCSVQTQ---HTPRTMQVHLTVQVPPKIYDIS 145 Query: 148 IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQP-ASGQPVSLKNISTDTS 206 + G N+ LTC + G P P SW+ + P A+P +GQ + + I+ D + Sbjct: 146 NDMTVNEGTNVTLTCLA-TGKPEPSISWRHIS------PSAKPFENGQYLDIYGITRDQA 198 Query: 207 GYYICTSSNE 216 G Y C++ N+ Sbjct: 199 GEYECSAEND 208 >gi|222136611 poliovirus receptor-related 4 [Homo sapiens] Length = 510 Score = 55.8 bits (133), Expect = 5e-08 Identities = 45/167 (26%), Positives = 70/167 (41%), Gaps = 17/167 (10%) Query: 160 LTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGT 219 L C S EG P P Y+W R L+ P G + ++T+ SG Y+C SNE + Sbjct: 268 LKCLS-EGQPPPSYNWTR---LDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSS 323 Query: 220 QFCNITVAVRSPSMNVALYVG------IAVGVVAALIIIGIIIYCCCCRGKDDNTEDKED 273 + +TV V P + V + VGV+AAL+ +++ + + Sbjct: 324 RDSQVTVDVLDPQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLM-----SRYHRRK 378 Query: 274 ARPNREAYEEPPEQLRE--LSREREEEDDYRQEEQRSTGRESPDHLD 318 A+ + YEE RE + R D R + + S G + H D Sbjct: 379 AQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPD 425 Score = 53.5 bits (127), Expect = 2e-07 Identities = 50/180 (27%), Positives = 74/180 (41%), Gaps = 12/180 (6%) Query: 4 KMW-PVLWTLCAVRVT-----VDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQ 57 +MW P W L + + A +ET DV+ G+ LPC Y + + G + Sbjct: 8 EMWGPEAWLLLLLLLASFTGRCPAGELET-SDVVTVVLGQDAKLPCFYRGDSGEQVGQVA 66 Query: 58 WDKLLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQS-DASITIDQLTMADNGTYE 116 W ++ + + S Y+ RV D S+ + AD G YE Sbjct: 67 WARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYE 126 Query: 117 CSVSLMSDLEGNTKSRVRLLVLVPP-SKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSW 175 C VS G+ ++R+RL VLVPP G E G + +C + EGSP P +W Sbjct: 127 CRVSTFP--AGSFQARLRLRVLVPPLPSLNPGPALEEGQGLTLAASC-TAEGSPAPSVTW 183 >gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42 precursor [Homo sapiens] Length = 2012 Score = 55.5 bits (132), Expect = 6e-08 Identities = 59/235 (25%), Positives = 96/235 (40%), Gaps = 34/235 (14%) Query: 7 PVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHT 66 P L T +V VTV P + R S G+ V +PC + I W K Sbjct: 581 PQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCV--VVSGDLPITITWQK------ 632 Query: 67 ERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLE 126 G + ++ + +S+ I L++ NG Y C + + Sbjct: 633 --------------DGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTC---IARNEA 675 Query: 127 GNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWK--RYNILNQE 184 + + +L+V VPP + + I G + L C S EG P P WK + + Q Sbjct: 676 AAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNC-SAEGYPVPTIVWKFSKGAGVPQF 734 Query: 185 QPLA-----QPASGQPVSLKNISTDTSGYYICTSSNEEGTQFC-NITVAVRSPSM 233 QP+A Q S + +K++ + SGYY+C SN+ G ++ + V+ P+M Sbjct: 735 QPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAM 789 Score = 38.9 bits (89), Expect = 0.006 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 8/110 (7%) Query: 115 YECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEG----ETIIGNNIQLTCQSKEGSPT 170 Y C E + RL V P + ++G + + G ++L C++ G P Sbjct: 195 YRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKAL-GHPE 253 Query: 171 PQYSWKRYNI-LNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGT 219 P Y W + N+ L + +G + ++NI SG Y+C SN GT Sbjct: 254 PDYRWLKDNMPLELSGRFQKTVTG--LLIENIRPSDSGSYVCEVSNRYGT 301 Score = 33.9 bits (76), Expect = 0.20 Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 27/148 (18%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPEC-GIEGETIIG--NN 157 ++ +D + +D G Y+C V + ++ + V++ P+ E ++ Sbjct: 369 NLIMDHMVKSDGGAYQCFVR-----KDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEP 423 Query: 158 IQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS----------GQPVSLKNISTDT-- 205 + L C K G+P P +W + P+ + S G VS NIS+ Sbjct: 424 VSLMCNVK-GTPLPTITWTL-----DDDPILKGGSHRISQMITSEGNVVSYLNISSSQVR 477 Query: 206 -SGYYICTSSNEEGTQFCNITVAVRSPS 232 G Y CT++N G + VR P+ Sbjct: 478 DGGVYRCTANNSAGVVLYQARINVRGPA 505 Score = 32.7 bits (73), Expect = 0.44 Identities = 22/89 (24%), Positives = 43/89 (48%), Gaps = 4/89 (4%) Query: 89 VSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGI 148 + +S +++ + I+ + +D+G+Y C V S+ G K RL V P Sbjct: 265 LELSGRFQKTVTGLLIENIRPSDSGSYVCEV---SNRYGTAKVIGRLYVKQPLKATISPR 321 Query: 149 EGETIIGNNIQLTCQSKEGSPTPQYSWKR 177 + ++ +G+ + L+C S G+ + SW R Sbjct: 322 KVKSSVGSQVSLSC-SVTGTEDQELSWYR 349 >gi|40254891 hypothetical protein FLJ20674 [Homo sapiens] Length = 540 Score = 55.1 bits (131), Expect = 8e-08 Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 33/178 (18%) Query: 155 GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPAS---------GQPVSLKNISTDT 205 G N+ LTCQ P + W R L Q + + QP+S +++ N S D Sbjct: 324 GGNVTLTCQVSGAYPPAKILWLRN--LTQPEVIIQPSSRHLITQDGQNSTLTIHNCSQDL 381 Query: 206 S-GYYICTSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIIIGIIIYC------ 258 GYYIC + + G + I ++V+ P L +G VG + +L+++G+ I Sbjct: 382 DEGYYICRADSPVGVREMEIWLSVKEP-----LNIGGIVGTIVSLLLLGLAIISGLLLHY 436 Query: 259 ----CCCRGKDDNTEDKEDARPNREAYEEPPEQLRELSREREEEDDYRQEEQRSTGRE 312 C G ++ +D ++ EE E+ E EEED E++ + RE Sbjct: 437 SPVFCWKVGNTSRGQNMDDVMVLVDSEEEEEEE------EEEEEDAAVGEQEGARERE 488 Score = 30.0 bits (66), Expect = 2.8 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 5/65 (7%) Query: 113 GTYECSVSLMSDLEGNTKSRVRLLVLVPP-SKPECGIEGETIIGN-NIQLTCQSKEGSPT 170 G Y C ++L + + K LLV PP S P+C + + G+ +QLTC+ G P Sbjct: 197 GNYTC-LALNQLSKRHRKVTTELLVYYPPPSAPQCWAQMAS--GSFMLQLTCRWDGGYPD 253 Query: 171 PQYSW 175 P + W Sbjct: 254 PDFLW 258 >gi|98986445 carcinoembryonic antigen-related cell adhesion molecule 5 preproprotein [Homo sapiens] Length = 702 Score = 54.3 bits (129), Expect = 1e-07 Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 22/172 (12%) Query: 88 RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147 R+ +SN + ++T+ +T D Y C + + + N V L VL P P Sbjct: 546 RLQLSNG----NRTLTLFNVTRNDARAYVCGIQ--NSVSANRSDPVTLDVLYGPDTPIIS 599 Query: 148 IEGETII-GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTS 206 + + G N+ L+C S +P+PQYSW+ I Q Q + + I+ + + Sbjct: 600 PPDSSYLSGANLNLSCHSAS-NPSPQYSWRINGIPQQHT--------QVLFIAKITPNNN 650 Query: 207 GYYIC------TSSNEEGTQFCNITVAVRSPSMNVALYVGIAVGVVAALIII 252 G Y C T N + ++ + SP ++ VGI +GV+ + +I Sbjct: 651 GTYACFVSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 702 Score = 42.4 bits (98), Expect = 6e-04 Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 20/149 (13%) Query: 88 RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147 R+ +SN + ++T+ +T D +Y+C + + V L VL P P Sbjct: 190 RLQLSNG----NRTLTLFNVTRNDTASYKCETQ--NPVSARRSDSVILNVLYGPDAPTIS 243 Query: 148 -IEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTS 206 + G N+ L+C + P QYSW Q S Q + + NI+ + S Sbjct: 244 PLNTSYRSGENLNLSCHAASNPPA-QYSWFVNGTFQQ--------STQELFIPNITVNNS 294 Query: 207 GYYICTSSNEE----GTQFCNITVAVRSP 231 G Y C + N + T ITV P Sbjct: 295 GSYTCQAHNSDTGLNRTTVTTITVYAEPP 323 Score = 41.6 bits (96), Expect = 0.001 Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 20/154 (12%) Query: 88 RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECG 147 R+ +SN+ + ++T+ +T D G YEC + + L + V L VL P P Sbjct: 368 RLQLSND----NRTLTLLSVTRNDVGPYECGIQ--NKLSVDHSDPVILNVLYGPDDPTIS 421 Query: 148 IEGETII-GNNIQLTCQSKEGSPTPQYSWKRYNILNQEQPLAQPASGQPVSLKNISTDTS 206 G N+ L+C + P QYSW + Q Q + + NI+ S Sbjct: 422 PSYTYYRPGVNLSLSCHAASNPPA-QYSWLIDGNIQQHT--------QELFISNITEKNS 472 Query: 207 GYYICTSSNEEG----TQFCNITVAVRSPSMNVA 236 G Y C ++N T ITV+ P +++ Sbjct: 473 GLYTCQANNSASGHSRTTVKTITVSAELPKPSIS 506 >gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF isoform a [Homo sapiens] Length = 6620 Score = 54.3 bits (129), Expect = 1e-07 Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 9/138 (6%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQL 160 ++ +D LT D+G Y C + GN + ++LV VPP + G + Q Sbjct: 6071 ALILDSLTGVDSGQYMC---FAASAAGNCSTLGKILVQVPPRFVNKVRASPFVEGEDAQF 6127 Query: 161 TCQSKEGSPTPQYSWKRYNIL----NQEQPLAQPASGQPV-SLKNISTDTSGYYICTSSN 215 TC + EG+P PQ W + L N+ Q L++P SG V ++ S + G Y C N Sbjct: 6128 TC-TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVN 6186 Query: 216 EEGTQFCNITVAVRSPSM 233 G+ + + ++SP + Sbjct: 6187 RLGSARASAELRIQSPML 6204 Score = 38.5 bits (88), Expect = 0.008 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 14/83 (16%) Query: 154 IGNNIQLTCQSKEGSPTPQYSWKRYNILNQEQP--------LAQPASGQPVSLKNISTDT 205 +G + L+CQ G+PTPQ SW++ +QP LAQ +++ +++ Sbjct: 23 VGKDATLSCQIV-GNPTPQVSWEK-----DQQPVAAGARFRLAQDGDLYRLTILDLALGD 76 Query: 206 SGYYICTSSNEEGTQFCNITVAV 228 SG Y+C + N G F + + V Sbjct: 77 SGQYVCRARNAIGEAFAAVGLQV 99 Score = 36.6 bits (83), Expect = 0.030 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 140 PPSKPECGIEGETII-GNNIQLTCQSKEGSPTPQYSWKRYNILNQE--QPLAQPASGQPV 196 P S P G T+ G + +L+C G P P+ WK+ L E + + + + Sbjct: 236 PASPPSTGTRTCTVTEGKHARLSCYVT-GEPKPETVWKKDGQLVTEGRRHVVYEDAQENF 294 Query: 197 SLKNISTDTS--GYYICTSSNEEGTQFCNITVAVRSPSM 233 LK + S G Y CT+SN G + ++ V VR P++ Sbjct: 295 VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAV 333 Score = 33.5 bits (75), Expect = 0.26 Identities = 37/154 (24%), Positives = 59/154 (38%), Gaps = 30/154 (19%) Query: 101 SITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLV-----------------LVPPSK 143 ++ I +T D+G Y + +S+ G S RLLV LVPP Sbjct: 5317 TLEIISVTREDSGQY---AAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRM 5373 Query: 144 PECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRYNI------LNQEQP---LAQPASGQ 194 E + G++I + + EG P P W R + + P +A A Sbjct: 5374 LERFTPKKVKKGSSITFSVKV-EGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQH 5432 Query: 195 PVSLKNISTDTSGYYICTSSNEEGTQFCNITVAV 228 + L ++ G Y C +SN G C+ ++ V Sbjct: 5433 SLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466 Score = 32.3 bits (72), Expect = 0.57 Identities = 37/181 (20%), Positives = 74/181 (40%), Gaps = 29/181 (16%) Query: 34 SQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKNYIHGELYKNRVSISN 93 ++GK L C Y T E + + D L+T R V++ + +N++ L+ + Sbjct: 250 TEGKHARLSC-YVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ----- 303 Query: 94 NAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETI 153 +D G Y C+ S +L G T S V L+V+ P+ P + Sbjct: 304 ----------------SDRGLYTCTAS---NLVGQTYSSV-LVVVREPAVPFKKRLQDLE 343 Query: 154 IGNNIQLTCQSKEGSPTPQYSWKRYNI---LNQEQPLAQPASGQPVSLKNISTDTSGYYI 210 + T + P+ + +W + + + + + + + ++++N+S D YI Sbjct: 344 VREKESATFLCEVPQPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYI 403 Query: 211 C 211 C Sbjct: 404 C 404 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,133,620 Number of Sequences: 37866 Number of extensions: 615707 Number of successful extensions: 5614 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 175 Number of HSP's successfully gapped in prelim test: 333 Number of HSP's that attempted gapping in prelim test: 3913 Number of HSP's gapped (non-prelim): 1621 length of query: 319 length of database: 18,247,518 effective HSP length: 102 effective length of query: 217 effective length of database: 14,385,186 effective search space: 3121585362 effective search space used: 3121585362 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.