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Search of human proteins with 50301232
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
(753 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 1525 0.0
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 1460 0.0
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 345 7e-95
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 338 1e-92
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 337 2e-92
gi|158303333 synaptopodin isoform B [Homo sapiens] 154 2e-37
gi|40353727 synaptopodin isoform A [Homo sapiens] 147 5e-35
gi|163965366 nascent polypeptide-associated complex alpha subuni... 107 3e-23
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 99 1e-20
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 99 1e-20
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 99 1e-20
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 99 1e-20
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 96 1e-19
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 94 4e-19
gi|160707881 formin 2 [Homo sapiens] 92 1e-18
gi|47132519 Ras association and pleckstrin homology domains 1 is... 88 3e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 88 3e-17
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 86 2e-16
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 83 8e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 82 2e-15
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 79 2e-14
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 79 2e-14
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 79 2e-14
gi|118402590 myosin XV [Homo sapiens] 78 3e-14
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 78 3e-14
gi|116284392 mucin 2 precursor [Homo sapiens] 77 8e-14
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 72 1e-12
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 72 1e-12
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 72 2e-12
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 72 2e-12
>gi|50301232 synaptopodin 2-like isoform b [Homo sapiens]
Length = 753
Score = 1525 bits (3949), Expect = 0.0
Identities = 753/753 (100%), Positives = 753/753 (100%)
Query: 1 METFEPISQEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLL 60
METFEPISQEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLL
Sbjct: 1 METFEPISQEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLL 60
Query: 61 TAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDAR 120
TAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDAR
Sbjct: 61 TAAPNPHSKGVLMFKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDAR 120
Query: 121 SLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQE 180
SLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQE
Sbjct: 121 SLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQE 180
Query: 181 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 240
LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF
Sbjct: 181 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 240
Query: 241 NRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG 300
NRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG
Sbjct: 241 NRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG 300
Query: 301 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFL 360
VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFL
Sbjct: 301 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFL 360
Query: 361 SAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEET 420
SAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEET
Sbjct: 361 SAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEET 420
Query: 421 KNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPK 480
KNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPK
Sbjct: 421 KNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPK 480
Query: 481 TPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAK 540
TPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAK
Sbjct: 481 TPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAK 540
Query: 541 RQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQA 600
RQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQA
Sbjct: 541 RQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQA 600
Query: 601 ARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARV 660
ARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARV
Sbjct: 601 ARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARV 660
Query: 661 QEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA 720
QEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA
Sbjct: 661 QEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA 720
Query: 721 SPSSCGFQVARPRFSATRTGLQAHVWRPGAGHQ 753
SPSSCGFQVARPRFSATRTGLQAHVWRPGAGHQ
Sbjct: 721 SPSSCGFQVARPRFSATRTGLQAHVWRPGAGHQ 753
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 1460 bits (3780), Expect = 0.0
Identities = 725/739 (98%), Positives = 727/739 (98%), Gaps = 6/739 (0%)
Query: 21 PDPVPE------LQDSFYAELQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF 74
P PV E Q + A+LQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF
Sbjct: 239 PHPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHSKGVLMF 298
Query: 75 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 134
KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD
Sbjct: 299 KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYLD 358
Query: 135 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 194
MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG
Sbjct: 359 MELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG 418
Query: 195 LQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254
LQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ
Sbjct: 419 LQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 478
Query: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314
RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP
Sbjct: 479 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 538
Query: 315 RSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA 374
RSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA
Sbjct: 539 RSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA 598
Query: 375 PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQN 434
PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQN
Sbjct: 599 PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQN 658
Query: 435 LDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMT 494
LDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMT
Sbjct: 659 LDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMT 718
Query: 495 PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTP 554
PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTP
Sbjct: 719 PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTP 778
Query: 555 GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRA 614
GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRA
Sbjct: 779 GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRA 838
Query: 615 TPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPT 674
TPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPT
Sbjct: 839 TPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPT 898
Query: 675 AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRF 734
AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRF
Sbjct: 899 AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRF 958
Query: 735 SATRTGLQAHVWRPGAGHQ 753
SATRTGLQAHVWRPGAGHQ
Sbjct: 959 SATRTGLQAHVWRPGAGHQ 977
Score = 59.7 bits (143), Expect = 1e-08
Identities = 148/609 (24%), Positives = 210/609 (34%), Gaps = 118/609 (19%)
Query: 199 PRAQSAPPEAAVLPP----SPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254
P +P E VL P SP P P+P QPG P + G
Sbjct: 92 PVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADG---- 147
Query: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314
P T +P P+R G P PP G P + S +P +P+ P
Sbjct: 148 -PATQE---KPRRPRRR----GPTRPTPP------GAPPDEVYL----SDSPAEPAPTIP 189
Query: 315 RSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPA 374
GP + S S P GA P P A + PLRP P
Sbjct: 190 ---GPPSQGDS----RVSSPSWEDGAALQPPPAEALLLP-------HGPLRPGPH-LIPM 234
Query: 375 PGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN-------SPNPE 427
GP P P + A+ LQ R +++ + K + + +PNP
Sbjct: 235 VGP-VPHPVAEDLTTTYTQKAKQAKLQ--RAESLQEKSIKEAKTKCRTIASLLTAAPNPH 291
Query: 428 LLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAP 487
++ + RA + +S GA A GA +P + A
Sbjct: 292 SKGVLMFKKRRQRA------KKYTLVSFGAAA-----GTGAEEEDGVPPTSESELDEEAF 340
Query: 488 KTPPPMTPKT---PPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 544
+T ++ P + + G G+ + E + GRG +LF +++ R
Sbjct: 341 SDARSLTNQSDWDSPYLDMELARAGSRASEGQGSGLGGQLSE---VSGRGVQLFEQQRQR 397
Query: 545 ADRYVVE--------GTPGPGLGPRPRSPSPTPS---LPPSWKYSPNIRAPPPI-----A 588
AD E G GL PR+ S P LPPS +P + +P P A
Sbjct: 398 ADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAP-VASPRPFQPGGGA 456
Query: 589 YNPLLSPFFPQAARTLPKAQSQGPRAT--------PKQGIKALDFMRHQP-----YQLKT 635
P S F A P Q Q P T PK+ +L + P Q T
Sbjct: 457 PTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPT 516
Query: 636 AMFCFDEVPPTPGPIASGSPKTAR------------VQEIRRFSTP--APQPTAEPLAPT 681
+ F P+ P+ SGSP T R + R TP AP+P A P A
Sbjct: 517 PLPSFTSGVPSHAPV-SGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSA-A 574
Query: 682 VLAPRAATTLDEPIWRTELASAPVPSP-APPPEAPRGLGASPSSCGFQVARPRFSATRTG 740
+ A+ L P+ + AP P P AP P + R S + + + A R G
Sbjct: 575 AMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQ---EARRRG 631
Query: 741 LQAHVWRPG 749
+ ++RPG
Sbjct: 632 TRKQMFRPG 640
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 345 bits (886), Expect = 7e-95
Identities = 291/843 (34%), Positives = 391/843 (46%), Gaps = 194/843 (23%)
Query: 9 QEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHS 68
++P S+ + + P + +A L+R+ESL EK +KEAK+KC++IA LLT APNP+S
Sbjct: 337 EDPRSEKDHSR-----PHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNS 391
Query: 69 KGVLMFKKRRQRAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFS 117
KGVLMFKKRR+RA+KYTLVS+G EEE+G SESE+DEE S
Sbjct: 392 KGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLS 451
Query: 118 DARSLTN--QSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRAD 175
D T DWDS +D+E + + G + L + +G+G +F ++R+R D
Sbjct: 452 DVDDNTQVVNFDWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMD 503
Query: 176 SSTQEL---------ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-- 224
T + +R + AA +GL++ Q E+ S + +
Sbjct: 504 QITAQKEEDKVGGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGL 561
Query: 225 ---PFQPGGGAPTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG 276
P Q G + +I NR+A+PF PG Q T P +P R S
Sbjct: 562 GHVPQQNGFSGTSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPI 613
Query: 277 GLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVT 336
PAPPP+ S+ P P +F+ GV S P++G P P P
Sbjct: 614 ADFPAPPPY-SAVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ---- 651
Query: 337 PGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 396
PAP S A ++ E ++R++RISVPA R
Sbjct: 652 -------PAPWSQPAFYDSS------------------------ERIASRDERISVPAKR 680
Query: 397 TGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSL 455
TGILQEA+RR T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSL
Sbjct: 681 TGILQEAKRRSTTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
Query: 456 GAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK-- 504
GAEACNFMQ A+ KTPPP+APK + P+TP +P P VAP
Sbjct: 739 GAEACNFMQSSSAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789
Query: 505 ------------------------PPSR--------GLLDGLVNGAASSAGIPEP----- 527
PP+R G G AS P+P
Sbjct: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
Query: 528 ----------------PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSL 571
P + GRG +LFAKRQSR ++YVV+ R+ SPTPSL
Sbjct: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSL 907
Query: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRH 628
P SWKYS N+RAPPP+AYNP+ SP +P AA + +Q + K+G + ALD M+H
Sbjct: 908 PASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKH 967
Query: 629 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 688
QPYQL ++F F G S K +++ P P A P + +
Sbjct: 968 QPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSV 1027
Query: 689 TTLDEPIWRTELASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHV 745
P AS+PV P P P +P+ S SS F RP+FSA ++G+ V
Sbjct: 1028 PAYTSPPSFFAEASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGVTIQV 1085
Query: 746 WRP 748
W+P
Sbjct: 1086 WKP 1088
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 338 bits (866), Expect = 1e-92
Identities = 289/840 (34%), Positives = 388/840 (46%), Gaps = 194/840 (23%)
Query: 9 QEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHS 68
++P S+ + + P + +A L+R+ESL EK +KEAK+KC++IA LLT APNP+S
Sbjct: 337 EDPRSEKDHSR-----PHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNS 391
Query: 69 KGVLMFKKRRQRAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFS 117
KGVLMFKKRR+RA+KYTLVS+G EEE+G SESE+DEE S
Sbjct: 392 KGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLS 451
Query: 118 DARSLTN--QSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRAD 175
D T DWDS +D+E + + G + L + +G+G +F ++R+R D
Sbjct: 452 DVDDNTQVVNFDWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMD 503
Query: 176 SSTQEL---------ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-- 224
T + +R + AA +GL++ Q E+ S + +
Sbjct: 504 QITAQKEEDKVGGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGL 561
Query: 225 ---PFQPGGGAPTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG 276
P Q G + +I NR+A+PF PG Q T P +P R S
Sbjct: 562 GHVPQQNGFSGTSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPI 613
Query: 277 GLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVT 336
PAPPP+ S+ P P +F+ GV S P++G P P P
Sbjct: 614 ADFPAPPPY-SAVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ---- 651
Query: 337 PGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 396
PAP S A ++ E ++R++RISVPA R
Sbjct: 652 -------PAPWSQPAFYDSS------------------------ERIASRDERISVPAKR 680
Query: 397 TGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSL 455
TGILQEA+RR T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSL
Sbjct: 681 TGILQEAKRRSTTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
Query: 456 GAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK-- 504
GAEACNFMQ A+ KTPPP+APK + P+TP +P P VAP
Sbjct: 739 GAEACNFMQSSSAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789
Query: 505 ------------------------PPSR--------GLLDGLVNGAASSAGIPEP----- 527
PP+R G G AS P+P
Sbjct: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
Query: 528 ----------------PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSL 571
P + GRG +LFAKRQSR ++YVV+ R+ SPTPSL
Sbjct: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSL 907
Query: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRH 628
P SWKYS N+RAPPP+AYNP+ SP +P AA + +Q + K+G + ALD M+H
Sbjct: 908 PASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKH 967
Query: 629 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 688
QPYQL ++F F G S K +++ P P A P + +
Sbjct: 968 QPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSV 1027
Query: 689 TTLDEPIWRTELASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHV 745
P AS+PV P P P +P+ S SS F RP+FSA ++G+ V
Sbjct: 1028 PAYTSPPSFFAEASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGVTIQV 1085
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 337 bits (864), Expect = 2e-92
Identities = 288/836 (34%), Positives = 387/836 (46%), Gaps = 194/836 (23%)
Query: 9 QEPLSQASYDKAPDPVPELQDSFYAELQRAESLQEKSIKEAKTKCRTIASLLTAAPNPHS 68
++P S+ + + P + +A L+R+ESL EK +KEAK+KC++IA LLT APNP+S
Sbjct: 337 EDPRSEKDHSR-----PHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNS 391
Query: 69 KGVLMFKKRRQRAKKYTLVSFGAA--AGTGAEEEDGVPP---------TSESELDEEAFS 117
KGVLMFKKRR+RA+KYTLVS+G EEE+G SESE+DEE S
Sbjct: 392 KGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLS 451
Query: 118 DARSLTN--QSDWDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRAD 175
D T DWDS +D+E + + G + L + +G+G +F ++R+R D
Sbjct: 452 DVDDNTQVVNFDWDSGLVDIE-----KKLNRGDKMEM---LPDTTGKGALMFAKRRERMD 503
Query: 176 SSTQEL---------ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPR-- 224
T + +R + AA +GL++ Q E+ S + +
Sbjct: 504 QITAQKEEDKVGGTPSREQDAAQT--DGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGL 561
Query: 225 ---PFQPGGGAPTPAPSI-----FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG 276
P Q G + +I NR+A+PF PG Q T P +P R S
Sbjct: 562 GHVPQQNGFSGTSETANIQRMVPMNRTAKPF-PGSVNQPAT-------PFSPTRNMTSPI 613
Query: 277 GLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVT 336
PAPPP+ S+ P P +F+ GV S P++G P P P
Sbjct: 614 ADFPAPPPY-SAVTPPP-DAFSRGVSS--PIAGPAQPP--------------PWPQ---- 651
Query: 337 PGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 396
PAP S A ++ E ++R++RISVPA R
Sbjct: 652 -------PAPWSQPAFYDSS------------------------ERIASRDERISVPAKR 680
Query: 397 TGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG-GAESGPEEDALSL 455
TGILQEA+RR T K MF +E K SPNPELLSL+QN + K G G +SGPEED LSL
Sbjct: 681 TGILQEAKRRSTTKPMFT--FKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSL 738
Query: 456 GAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK------TPPPMTPKTP---PPVAPK-- 504
GAEACNFMQ A+ KTPPP+APK + P+TP +P P VAP
Sbjct: 739 GAEACNFMQSSSAKQ---------KTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789
Query: 505 ------------------------PPSR--------GLLDGLVNGAASSAGIPEP----- 527
PP+R G G AS P+P
Sbjct: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTP 849
Query: 528 ----------------PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSL 571
P + GRG +LFAKRQSR ++YVV+ R+ SPTPSL
Sbjct: 850 TVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQ--AHAARAQSPTPSL 907
Query: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQG---IKALDFMRH 628
P SWKYS N+RAPPP+AYNP+ SP +P AA + +Q + K+G + ALD M+H
Sbjct: 908 PASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKH 967
Query: 629 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 688
QPYQL ++F F G S K +++ P P A P + +
Sbjct: 968 QPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSV 1027
Query: 689 TTLDEPIWRTELASAPV---PSPAPPPEAPRGLGASPSSCGFQVARPRFSATRTGL 741
P AS+PV P P P +P+ S SS F RP+FSA ++G+
Sbjct: 1028 PAYTSPPSFFAEASSPVSASPVPVGIPTSPK--QESASSSYFVAPRPKFSAKKSGV 1081
>gi|158303333 synaptopodin isoform B [Homo sapiens]
Length = 685
Score = 154 bits (390), Expect = 2e-37
Identities = 156/518 (30%), Positives = 216/518 (41%), Gaps = 76/518 (14%)
Query: 237 PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP-PPFLSSQGPTPLP 295
PS+ NR+ARPF G+Q P TS + R +P G +PAP PP L + P P
Sbjct: 233 PSVVNRTARPF--GIQA--PGGTSQMER--SPMLERRHFGEKAPAPQPPSLPDRSPRPQR 286
Query: 296 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 355
S P +P S RP+ G PP +
Sbjct: 287 HIMSRSPMVERRMMGQRSPASE--------------RRPL--GNFTAPPTYTETLSTAPL 330
Query: 356 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA-RRRGTRKQMFR 414
AS S P P + +P S+ + +VPA++TGIL+E+ RRG+RK MF
Sbjct: 331 ASWVRSPPSYSVLYPSS--------DPKSSHLKGQAVPASKTGILEESMARRGSRKSMF- 381
Query: 415 PGKEETKNSPNPELLSLVQNLDEKPR-AGGAESGPEEDALSLGAEACNFMQPVGARSYKT 473
E+ K +PNP+LL LVQ DEK R E G EE+ +LGAEA NF Q R +
Sbjct: 382 TFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD-RA 440
Query: 474 LPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 533
P + P A P P P P++ L + G+
Sbjct: 441 SPAAAEEVVPEWASCLKSPRIQAKPKP----KPNQNLSEA-----------------SGK 479
Query: 534 GGELFAKRQSRADRYVVEGTP-GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPL 592
G EL+A+RQSR ++YV+E + P L R PSPT SLP SWKY N +A
Sbjct: 480 GAELYARRQSRMEKYVIESSSHTPELA---RCPSPTMSLPSSWKYPTNAPGAFRVASR-- 534
Query: 593 LSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEV--PPTPGPI 650
SP ART P + G P+ G+ + + PYQL+ ++F + P P
Sbjct: 535 -SP-----ARTPPASLYHG--YLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPR 586
Query: 651 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 710
A+ K + + + A P+ P+ +P T+ + + S P
Sbjct: 587 AASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS 646
Query: 711 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQAHVWRP 748
P R S Q RP FS G++A VW+P
Sbjct: 647 PVSPSRAW----SPRAKQAPRPSFSTRNAGIEAQVWKP 680
Score = 36.6 bits (83), Expect = 0.088
Identities = 61/221 (27%), Positives = 82/221 (37%), Gaps = 21/221 (9%)
Query: 156 LSEVSGRGVQLFEQQRQR-------ADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEA 208
LSE SG+G +L+ +++ R + S T ELAR M + P +AP
Sbjct: 473 LSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYP---TNAPGAF 529
Query: 209 AVLPPSPLPAPVAS-PRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLA 267
V SP P AS + P G P P+ + P L P P A
Sbjct: 530 RVASRSPARTPPASLYHGYLPENGVLRPEPT--KQPPYQLRPSLFVLSPIKEPAKVSPRA 587
Query: 268 PKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLY 327
A S L P P +G P PS PS + S + S TA S Y
Sbjct: 588 ASPAKPSSLDLVPNLP-----KGALP-PSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPY 641
Query: 328 IPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPL-RPS 367
PV+P A P A + ST + + A + +PS
Sbjct: 642 -GGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPS 681
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 147 bits (370), Expect = 5e-35
Identities = 157/530 (29%), Positives = 216/530 (40%), Gaps = 86/530 (16%)
Query: 237 PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP-PPFLSSQGPTPLP 295
PS+ NR+ARPF G+Q P TS + R +P G +PAP PP L + P P
Sbjct: 233 PSVVNRTARPF--GIQA--PGGTSQMER--SPMLERRHFGEKAPAPQPPSLPDRSPRPQR 286
Query: 296 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 355
S P +P S RP+ G PP +
Sbjct: 287 HIMSRSPMVERRMMGQRSPASE--------------RRPL--GNFTAPPTYTETLSTAPL 330
Query: 356 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA-RRRGTRKQMFR 414
AS S P P + +P S+ + +VPA++TGIL+E+ RRG+RK MF
Sbjct: 331 ASWVRSPPSYSVLYPSS--------DPKSSHLKGQAVPASKTGILEESMARRGSRKSMF- 381
Query: 415 PGKEETKNSPNPELLSLVQNLDEKPR-AGGAESGPEEDALSLGAEACNFMQPVGARSYKT 473
E+ K +PNP+LL LVQ DEK R E G EE+ +LGAEA NF Q R +
Sbjct: 382 TFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD-RA 440
Query: 474 LPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 533
P + P A P P P P++ L + G+
Sbjct: 441 SPAAAEEVVPEWASCLKSPRIQAKPKP----KPNQNLSEA-----------------SGK 479
Query: 534 GGELFAKRQSRADRYVVEGTP-GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPL 592
G EL+A+RQSR ++YV+E + P L R PSPT SLP SWKY N +A
Sbjct: 480 GAELYARRQSRMEKYVIESSSHTPELA---RCPSPTMSLPSSWKYPTNAPGAFRVASR-- 534
Query: 593 LSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEV--PPTPGPI 650
SP ART P + G P+ G+ + + PYQL+ ++F + P P
Sbjct: 535 -SP-----ARTPPASLYHG--YLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPR 586
Query: 651 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 710
A+ K + + + A P+ P+ +P T+ + + S P
Sbjct: 587 AASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS 646
Query: 711 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQAH----------VWRPGA 750
P R S Q RP FS G++A W PGA
Sbjct: 647 PVSPSRAW----SPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGA 692
Score = 69.3 bits (168), Expect = 1e-11
Identities = 115/449 (25%), Positives = 153/449 (34%), Gaps = 82/449 (18%)
Query: 156 LSEVSGRGVQLFEQQRQRAD-------SSTQELARVEPAAMLNGEGLQSPPRAQSAPPEA 208
LSE SG+G +L+ +++ R + S T ELAR M + P +AP
Sbjct: 473 LSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPT---NAPGAF 529
Query: 209 AVLPPSPLPAPVASP-RPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLA 267
V SP P AS + P G P P+ + P L P P A
Sbjct: 530 RVASRSPARTPPASLYHGYLPENGVLRPEPT--KQPPYQLRPSLFVLSPIKEPAKVSPRA 587
Query: 268 PKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLY 327
A S L P P +G P PS PS + S + S TA S Y
Sbjct: 588 ASPAKPSSLDLVPNLP-----KGALP-PSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPY 641
Query: 328 IPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSARE 387
PV+P A P A + ST + + A R + P +P PGA PPS+ +
Sbjct: 642 -GGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLD 700
Query: 388 QRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESG 447
+S + PG+ + +SP P L P + S
Sbjct: 701 GWVSPGP------------------WEPGRGSSMSSPPP--------LPPPPPMSPSWSE 734
Query: 448 PEEDALSLGAEA---CNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 504
L EA +Q + AR+ +P + P P +P PP P
Sbjct: 735 RSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPP 794
Query: 505 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 564
PP P PPR+ R + R PG P PRS
Sbjct: 795 PP------------------PPPPRM----------RSPQPARPGSAAVPGAAFAPIPRS 826
Query: 565 PSPTPSLPPSWKYSPNIRAPPPIAYNPLL 593
P P PS SP R+P P P L
Sbjct: 827 PLPA---GPSSCTSP--RSPLPAPPRPFL 850
Score = 45.4 bits (106), Expect = 2e-04
Identities = 138/623 (22%), Positives = 207/623 (33%), Gaps = 159/623 (25%)
Query: 218 APVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 277
+P+ R F AP P PS+ +RS RP + + P + +P LG
Sbjct: 257 SPMLERRHFGEKAPAPQP-PSLPDRSPRP-QRHIMSRSPMVERRMMGQRSPASERRPLGN 314
Query: 278 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPV--SGSPSTPRSSG---PVTATS-------- 324
+ APP + + PL S+ PS++ + S P + G P + T
Sbjct: 315 FT-APPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMAR 373
Query: 325 -----SLYIPAPSRPVTPG----------------------GAPEPPAPPSAAAMTSTAS 357
S++ VTP G E P A+ + AS
Sbjct: 374 RGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPF-----ALGAEAS 428
Query: 358 IFLSAPLRPSARPEAPAPGPGAPE-------------PPSAREQRISVPAARTGILQEAR 404
F P P R A PE P Q +S + + L R
Sbjct: 429 NFQQEPA-PRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARR 487
Query: 405 RRGTRKQMFRPGKE--ETKNSPNPELLSLVQNLDEKPRAGGA-ESGPEEDALSLGAEACN 461
+ K + E P+P + SL + A GA A + A +
Sbjct: 488 QSRMEKYVIESSSHTPELARCPSPTM-SLPSSWKYPTNAPGAFRVASRSPARTPPASLYH 546
Query: 462 FMQPVGARSYKTLPHVTPKTPPPMAP--------KTPPPMTPKTPPPVAPKPPSRGLLDG 513
P P T + P + P K P ++P+ P KP S L+
Sbjct: 547 GYLPENG---VLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPA--KPSSLDLVPN 601
Query: 514 LVNGAAS-SAGIPEPPR-------------LQGR------GGELFAKRQSRADRYVVEGT 553
L GA S +P P R LQ GG++ SRA +
Sbjct: 602 LPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQA 661
Query: 554 PGPGLGPR-------------PRSPSPTP--SLPPS----------WK--YSPNIRAPPP 586
P P R P SP TP S PPS W+ ++ +PPP
Sbjct: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP 721
Query: 587 IAYNPLLSPFFPQAARTLPKAQSQG-PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 645
+ P +SP + + + + + +++ P + Q + A + + +
Sbjct: 722 LPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRK------------- 768
Query: 646 TPGPIASGSPKTARVQEIRRFS---TPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS 702
S SP++A + R FS P P P P P + +P+ A R A+
Sbjct: 769 ------SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA--------RPGSAA 814
Query: 703 APVPSPAPPPEAPRGLGASPSSC 725
P + AP P +P L A PSSC
Sbjct: 815 VPGAAFAPIPRSP--LPAGPSSC 835
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 107 bits (268), Expect = 3e-23
Identities = 183/727 (25%), Positives = 248/727 (34%), Gaps = 139/727 (19%)
Query: 105 PTSESELDEEAFSDARSLTNQSDWDSPYLDMELARAGSRASEGQGSG-----LGGQLSEV 159
PT +S A S +LT +D SP L + ++ R +GS +G S V
Sbjct: 771 PTEDSGASATASSKG-TLTYLADSPSP-LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPV 828
Query: 160 SGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAP 219
S + S A + +G +P P+ LPP P P
Sbjct: 829 SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTP 888
Query: 220 VASPRPFQ---PGGGAPTPAPSIFNRSARP----FTPGLQGQRPTTTSVIFRPLAPKRAN 272
PF P AP AP++ S+ P TP +G P + S P P
Sbjct: 889 SVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI-PASPSPKGAPTPPAATP 947
Query: 273 DSLGG--LSPAP-----PPFLSSQGP-----TPLPSFTSGVPSHAPVS--GSPSTPRSSG 318
S G +P+P PP + P TP P P+ P S G P+TP G
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 319 ---PVTATSSLYIPAPSRPVTPGGAPEPPA--PPSAAAMTSTASIFLSAPLRPSARPEAP 373
P T +P+ P GA PPA PPS + + AP P+A +P
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 374 APGP------GAPEPPSAREQR-----------------ISVPAARTGILQEARRRG--T 408
GP GAP PP+A + P + G L +G T
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Query: 409 RKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGA 468
P + +P P+ GG + P + A + A P G
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT--TPAATPPSPKGG 1185
Query: 469 RSYKTLPHVTPKTP--PPMAPK----TPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS- 521
+ + P P TP P +PK TP P T P P P GL GA ++
Sbjct: 1186 LATPS-PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244
Query: 522 ----------------AGIPEPPRLQG---RGGELFAKRQSRADRYVVEGTP-----GPG 557
G P PP +GG + + VV TP GP
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV--TPPSPKGGPA 1302
Query: 558 LGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKA--QSQGPRAT 615
P +P+P + PPS K SP P P ++P P+ TLP S+G T
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362
Query: 616 P--KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQP 673
P K+G PP P G P A + P P
Sbjct: 1363 PSSKEG----------------------PTPPAATPSHKGGP--AMTPPSPKRGPAIPSP 1398
Query: 674 TAEPLAPTV--LAPRAATTLDEPIWRTELA-------SAPVPSP-----APPPEAPRGLG 719
+P +P V L+P+ A P+ R A + P +P AP AP+G
Sbjct: 1399 KGDPTSPAVIPLSPKKAPA--TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456
Query: 720 ASPSSCG 726
A+PSS G
Sbjct: 1457 ATPSSKG 1463
Score = 90.9 bits (224), Expect = 4e-18
Identities = 137/563 (24%), Positives = 193/563 (34%), Gaps = 55/563 (9%)
Query: 193 EGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARP------ 246
+G + P + AP A PPSP P P P A TP PS+ A P
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP-PSLKGGLATPPHKGAP 1287
Query: 247 ----FTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPT---PLPSFTS 299
TP P T+ P P S G PPP + P P P T
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347
Query: 300 GVPSHAPVS-GSPSTPRSSG---PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 355
+P+ P S G P+TP S P AT S P +P P P+P TS
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP--TSP 1405
Query: 356 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRP 415
A I PL P P P GA P ++ PA L++A K P
Sbjct: 1406 AVI----PLSPKKAPATPVTREGAATPSKG---DLTPPAVTPVSLKKAPATSAPKG--GP 1456
Query: 416 GKEETKNSPN-PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTL 474
+K P P + P+ S P++ + + V S K +
Sbjct: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV 1516
Query: 475 PHVTPKTPPPMAPKTPPPMTPKTPPPVAPK----PPSRGLLDGLVNGAASSAGIPEPPRL 530
P P+AP T ++ KTP +APK PP+ V + IP P
Sbjct: 1517 PATPSSRRDPIAP-TATLLSKKTPATLAPKEALIPPAM-----TVPSPKKTPAIPTPKEA 1570
Query: 531 QGRGGELFAKRQSRADRYVVEGTPGPG--------LGPRPR-SPSPTPSLPPSWKYSPNI 581
A +G P P P P+ +P+P PPS + P
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 582 RAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFD 641
AP +P ++P + + T P + + AT Q K L + P LK +
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLP-AKKGPTALKEVL---- 1685
Query: 642 EVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELA 701
V P P + T + + ++ S +P +P A +T P+ +
Sbjct: 1686 -VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKD 1744
Query: 702 SAPVPSPAPPPEAPRGLGASPSS 724
S+ +P+G A P S
Sbjct: 1745 SSKTAKGKDASHSPKGPLAPPES 1767
Score = 69.3 bits (168), Expect = 1e-11
Identities = 110/435 (25%), Positives = 150/435 (34%), Gaps = 71/435 (16%)
Query: 186 PAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSAR 245
PA + EG +P + PP AV P S AP S P GG TP +
Sbjct: 1416 PATPVTREGAATPSKGDLTPP--AVTPVSLKKAPATS----APKGGPATP-----SSKGD 1464
Query: 246 PFTPGLQGQRPTTTSVIFRPLAPKR-ANDSLGGLSPA-PPPFLSSQGPTPLPSFTSGVPS 303
P P + P P APK+ A S +PA P P + P +PS VP+
Sbjct: 1465 PTLPAVTPPSPK------EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA 1518
Query: 304 HAPVSGSPSTPRSS-----GPVT-ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTAS 357
P P ++ P T A IP +P P P P A A S+
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE 1578
Query: 358 IFLSAPLRPSARPEAPAPG----PGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMF 413
+ PS AP+P P A PS +E P A T E K
Sbjct: 1579 ASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE--APTPPAVTPPSPE-------KGPA 1629
Query: 414 RPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKT 473
P + T SP P S +++ P + + G S G A P +
Sbjct: 1630 TPAPKGTPTSP-PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK--GPTALKEVLV 1686
Query: 474 LPHVTPKTPPPMAPKTPPPMTPK---TPPPVAPKPPSRGLLDGLVNGAASSAGIP----- 525
P TP AP P T K T PP+ P P ++ G ++ A + +P
Sbjct: 1687 AP-APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745
Query: 526 -----------------EPPRLQGR---GGELFAKRQSRADRYVVEGTPGPGLGPRPRSP 565
PP + F K + + V P P + P +P
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVS-LPLAP 1804
Query: 566 SPTPSLPPSWKYSPN 580
SP P+LPP ++ P+
Sbjct: 1805 SPVPTLPPKQQFLPS 1819
Score = 66.6 bits (161), Expect = 8e-11
Identities = 147/584 (25%), Positives = 200/584 (34%), Gaps = 120/584 (20%)
Query: 193 EGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA---------------- 236
+G P + AP AV PPSP P GG TP+
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 237 -PSIFNRSAR--PFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTP 293
P++ S + P P +G PT+ +VI PL+PK+A + A P P
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGD-PTSPAVI--PLSPKKAPATPVTREGAATPSKGDLTPPA 1437
Query: 294 L-PSFTSGVPSHAPVSGSPSTPRSSGPVT------------------ATSSLYIPAPSRP 334
+ P P+ + G P+TP S G T ATSS AP+ P
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497
Query: 335 VTPGGAPEPPAP-PSAAAMTSTASIFLSAPLRPSARPEAPAPGP---GAPEPPSAREQRI 390
P GAP PA PS+ P PS+R + AP P + +
Sbjct: 1498 -APMGAPTLPAVIPSSPK---------EVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 391 SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEE 450
+P A T + + P +K + +P ++ P P+E
Sbjct: 1548 LIPPAMT-VPSPKKTPAIPTPKEAPATPSSKEASSPPAVT--------PSTYKGAPSPKE 1598
Query: 451 DALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGL 510
L A P + T P VTP + P P TP P T PPV P L
Sbjct: 1599 ---LLIPPAVTSPSP---KEAPTPPAVTPPS-PEKGPATPAPKGTPTSPPVTPS----SL 1647
Query: 511 LDGLVNGAASSA--GIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPT 568
D + A+ + G P +G L AK+ A + V+ P P +PT
Sbjct: 1648 KDSPTSPASVTCKMGATVPQASKG----LPAKKGPTALKEVL---VAPAPESTPIITAPT 1700
Query: 569 PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRH 628
P + K S PPI +P K S+GP +T + +
Sbjct: 1701 RKGPQTKKSS---ATSPPICPDP------------SAKNGSKGPLST----VAPAPLLPV 1741
Query: 629 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 688
Q KTA G AS SPK + STP E + P P +A
Sbjct: 1742 QKDSSKTA----------KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP---KPESA 1788
Query: 689 TTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARP 732
+ P L AP P P PP+ PSS G + P
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQ----FLPSSPGLVLESP 1828
Score = 63.9 bits (154), Expect = 5e-10
Identities = 139/609 (22%), Positives = 211/609 (34%), Gaps = 116/609 (19%)
Query: 195 LQSPPRAQSAPPEAAVLPPSPL---PAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPG- 250
L+S P A P A +P S + P V +P APT + + P + G
Sbjct: 415 LKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTI---AAAPTTTFEVATCVSPPMSSGP 471
Query: 251 LQGQRPTT-TSVIFRPLAPKRANDSLGGLS--PAPPPFLSSQGPTPLPSFT--------- 298
+ PT+ +++ P+APK + + P PP + LPS
Sbjct: 472 ISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKD 531
Query: 299 -SGVPSHAPVSGSPSTPRSSGPVTATSSLYIP--------APSRPVTPGGAPEPPAPPSA 349
VP A + G+P +P +G T +P +PS T +PE P P A
Sbjct: 532 LQTVP--ASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST-SSSPEIPLSPEA 588
Query: 350 AAMTSTASIFLSAPLRPSARPEAPAPGP-GAPEPPSA-REQRISVPAARTGILQEARRRG 407
+ A L PL P +P + P G S + + P + +L+ +
Sbjct: 589 ----TLAKKSLGEPL-PIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITP 643
Query: 408 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAES-GPEEDALSLGAEACNFMQPV 466
T + +P + P G S P+ + G + P
Sbjct: 644 TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPT 703
Query: 467 GARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP----PVAPKPPSRGLLDGLVNGAASSA 522
+ + P T P+A P PK+ P P A PP +DG+ + +A +
Sbjct: 704 ASENCPVAPS-PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762
Query: 523 GIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSP--- 579
P A S+ + +P P LG S SP PP+ K S
Sbjct: 763 VASSPKECPTEDSGASATASSKGTLTYLADSPSP-LGV---SVSPQTKRPPTKKGSAGPD 818
Query: 580 ----NIRAP----------------------PPIAYNPLLSPFFPQAART-------LPK 606
N+ +P P ++P +P P+ A T PK
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP--TPPSPKGAPTPSAVTPLSPK 876
Query: 607 AQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGP-------IASGSPKTAR 659
+ P+ TP + L F + E P TP P + S SPK AR
Sbjct: 877 GVTLPPKETPTPSVVNLPFPK--------------EGPATPAPKQAPALSMTSSSPKKAR 922
Query: 660 VQEIRRF--STPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRG 717
+ ++P+P+ P A T +P+ P W AP P PA P +P+G
Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW------APTP-PAATPPSPKG 975
Query: 718 LGASPSSCG 726
A+PS G
Sbjct: 976 GPATPSPKG 984
Score = 48.5 bits (114), Expect = 2e-05
Identities = 60/216 (27%), Positives = 79/216 (36%), Gaps = 36/216 (16%)
Query: 192 GEGLQSPPRAQSAPP----EAAVLPPSP---LPAPVASPRPFQPGGGAPTP--APSIFNR 242
GE ++ P + P E AVLP S + A + P P P +P P P
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
Query: 243 SARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLG-----GLSPAPPPFLSSQGPTPLPSF 297
A PF P+ +++ PL S G G +P P FL + P+
Sbjct: 63 QASPF--------PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPA 114
Query: 298 TSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEP--PAPPSAAAMTST 355
+ S TP SS P+ +L AP P +PPS A S
Sbjct: 115 ALALASPMIAPTLKGTPSSSAPL----ALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG 170
Query: 356 ASIFLSAPLRPSAR-------PEAPAPGP-GAPEPP 383
+ I LSAP+ PS P P P G P PP
Sbjct: 171 SVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPP 206
Score = 44.3 bits (103), Expect = 4e-04
Identities = 83/335 (24%), Positives = 117/335 (34%), Gaps = 84/335 (25%)
Query: 199 PRAQSAPPEAAVLPPSP-----LPAPVASPR------------PFQPGG----------- 230
P + AP AV PPSP PAP +P P P
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 231 ---GAPT-------------PAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 274
G P PAP P G Q ++ + TS P P N S
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP-DPSAKNGS 1726
Query: 275 LGGLSP-APPPFLSSQGPTPLPSFTSGVPSHAPVSG-SPSTPRSSGPVTAT--------- 323
G LS AP P L Q + + SH+P +P ++S P+TA
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAKGKDA-SHSPKGPLAPPESKASTPLTAAAFEKVLPKP 1785
Query: 324 -SSLYIPAPSRPVTPGGAPEP--PAPPSAAAMTSTASIFLSAPLRPSARPE--------A 372
S+ APS PV+ AP P PP + S+ + L +P +P A +
Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIP 1845
Query: 373 PAPGPGA----------PEPPSAREQRISVPAARTGILQEARRRGTRKQMFR--PGKEE- 419
P P G P P SA + P+A+ + + + GT P EE
Sbjct: 1846 PEPISGGVPFQSVLVNMPTPKSAGIP-VPTPSAKQPVTKNNKGSGTESDSDESVPELEEQ 1904
Query: 420 --TKNSPNPELLSLVQNLDEKPRAGGAESGPEEDA 452
T+ + L+ +DE+P + +S E+ A
Sbjct: 1905 DSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKA 1939
Score = 38.5 bits (88), Expect = 0.023
Identities = 123/559 (22%), Positives = 184/559 (32%), Gaps = 88/559 (15%)
Query: 181 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 240
L +V + N +G SPP S P V P + + + VAS P P+
Sbjct: 188 LNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVAS---------LPQTTPTTT 238
Query: 241 NRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSG 300
A P Q + T +SV+ P P SL P PP S LP TS
Sbjct: 239 LAIASP-----QVKDTTISSVLISPQNP----GSLSLKGPVSPPAALSLSTQSLPVVTSS 289
Query: 301 VPSHAPVSGSPSTPRSSGPVTA---TSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTAS 357
+ P + P P S G A SS P +P + +ST +
Sbjct: 290 QKTAGP-NTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA 348
Query: 358 IFLS----APLRPSARPEAPAP-------GPGAPEPPSAREQRISVPAARTGILQEARRR 406
+ S P PS PA P + PS P+ +
Sbjct: 349 SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLS 408
Query: 407 GTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPV 466
T + + T + P LV + S+G P
Sbjct: 409 PTTSLILKSSPNATYHYP------LVAQM---------------PVSSVGTTPLVVTNPC 447
Query: 467 G-ARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP-----PPVAPKPPSRGLLDGLVNGAAS 520
A + T V PPM+ + P +P PVAPK PS + L
Sbjct: 448 TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL--RIPV 505
Query: 521 SAGIPEPPRLQGRGGELFAKRQSRADRYVV----EGTP----GPGLGPRPRSPSPTPSLP 572
S +P+P L+ + K ++ D V EG P GL + + P+ P +
Sbjct: 506 SPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTK-KDPTVLPLVQ 564
Query: 573 PSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQ 632
+ K SP+ ++ + +P + P P+A P P + + +
Sbjct: 565 AAPKNSPSFQS---TSSSPEI-PLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620
Query: 633 LKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEP--LAPTVLAPRAA-T 689
+KT + P + GP+ S T V P +A+P +APT + T
Sbjct: 621 IKTDSYA---GPDSAGPLLKSSLITPTVAAF-------PLESADPAGVAPTTAKGTSTYT 670
Query: 690 TLDEPIWRTELASAPVPSP 708
T P ++ AP P
Sbjct: 671 TTASPFLEGTVSLAPKNHP 689
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 99.0 bits (245), Expect = 1e-20
Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%)
Query: 154 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 208
G+ S + Q E+ + + T + LA+ P A G L +P P+ A
Sbjct: 166 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 225
Query: 209 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 268
+ P P P + S P P APT S P TP + PTTT P P
Sbjct: 226 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 275
Query: 269 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 328
K PAP + P P+ T P+ P +P+TP+ P T
Sbjct: 276 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 316
Query: 329 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 384
PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P +
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376
Query: 385 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 444
+E + P P TK++P ++P
Sbjct: 377 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 408
Query: 445 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 504
+S P +P + + P TPK P P PK P P TPK P P PK
Sbjct: 409 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 456
Query: 505 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 564
P A ++ P P + + + + TP P
Sbjct: 457 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 565 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 622
P+PT L P+ P P A P P+AA P + TPK+
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 555
Query: 623 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 681
P K + P TP A +PK ++ + P+ P + LAPT
Sbjct: 556 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602
Query: 682 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 716
+TT D+P T +AP P P P+
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637
Score = 90.1 bits (222), Expect = 7e-18
Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%)
Query: 171 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 227
++ A ++T+E A EPA E +P +SAP P P P P P
Sbjct: 260 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 313
Query: 228 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 287
P APT + + P + PTT P APK+ + +P P +
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 368
Query: 288 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 347
+ P P T+ PS P+TP+ P T S+ P T AP P P
Sbjct: 369 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
S T+T + P P+ P+ PAP P P P + +E + +
Sbjct: 419 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 463
T K+ P + PE L EKP A + PEE A + E
Sbjct: 476 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 528
Query: 464 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 523
+P P+ TPK P P PK P P TPK P P PK + G A ++
Sbjct: 529 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 584
Query: 524 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 578
P P + + A ++ P P G P P+ P+PT P+ +
Sbjct: 585 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 643
Query: 579 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 638
P AP + +P P A + L ++GP +T + P K
Sbjct: 644 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 690
Query: 639 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 696
+ P TP A +PK PAP T E PT TT EP I
Sbjct: 691 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 697 RTELASAPVPSPAPPPEA 714
++ S P S P P+A
Sbjct: 737 KSPDESTPELSAEPTPKA 754
Score = 61.2 bits (147), Expect = 3e-09
Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%)
Query: 233 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 289
PTP P + + + G + P T++ ++ + ++P P PP +
Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137
Query: 290 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 347
T L + + + G TS+ + + AP A P
Sbjct: 138 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 197
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
+ A T+T L+ P P+ P+ PA P P P + + S P
Sbjct: 198 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 242
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 465
T K+ P TK++P E A + P+E A + E P
Sbjct: 243 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 288
Query: 466 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 521
+S T P TPK P P PK P P TPK P P PK P+ +
Sbjct: 289 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 338
Query: 522 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 581
P P+ + A + TP P+ P+PT + PS +P
Sbjct: 339 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 387
Query: 582 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 637
AP P + P ++A T PK S P
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 428
Query: 638 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 697
P P P P +E PAP EP APT A TT EP
Sbjct: 429 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 477
Query: 698 TELASAPVPSPAPPPEAPRGL 718
T +AP P P L
Sbjct: 478 TPKETAPTTPKKLTPTTPEKL 498
Score = 60.5 bits (145), Expect = 6e-09
Identities = 64/245 (26%), Positives = 88/245 (35%), Gaps = 28/245 (11%)
Query: 197 SPPRAQSAPPEAAV--LPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254
+P P+AA P P P P P P APT + P TP +G
Sbjct: 526 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-----KETAPTTP--KGT 578
Query: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314
PTT K A L + P S+ P P+ G P +P+TP
Sbjct: 579 APTTLKEPAPTTPKKPAPKELAPTTTKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTP 636
Query: 315 RSSGPVT----ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLS-------AP 363
+ P T A ++L PAP+ P P AP+ AP + TST S + AP
Sbjct: 637 KEPAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAP 694
Query: 364 LRPS----ARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEE 419
P P+ PAP PP+ E + ++ T + P +
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754
Query: 420 TKNSP 424
+NSP
Sbjct: 755 LENSP 759
Score = 37.0 bits (84), Expect = 0.068
Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Query: 641 DEVPPTPGPIASGSPKTARVQEIRRFSTPA--PQPTAEPLAPTVLAPRAATTLDEPIWRT 698
+ P TP AS +PK I+ T P PT APT A TT EP T
Sbjct: 215 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274
Query: 699 ELASAPVPSPAPPPEAPRGLGASP 722
AP + P P + +P
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTP 298
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 99.0 bits (245), Expect = 1e-20
Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%)
Query: 154 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 208
G+ S + Q E+ + + T + LA+ P A G L +P P+ A
Sbjct: 207 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 266
Query: 209 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 268
+ P P P + S P P APT S P TP + PTTT P P
Sbjct: 267 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 316
Query: 269 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 328
K PAP + P P+ T P+ P +P+TP+ P T
Sbjct: 317 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 357
Query: 329 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 384
PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P +
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417
Query: 385 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 444
+E + P P TK++P ++P
Sbjct: 418 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 449
Query: 445 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 504
+S P +P + + P TPK P P PK P P TPK P P PK
Sbjct: 450 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 497
Query: 505 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 564
P A ++ P P + + + + TP P
Sbjct: 498 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 565 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 622
P+PT L P+ P P A P P+AA P + TPK+
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 596
Query: 623 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 681
P K + P TP A +PK ++ + P+ P + LAPT
Sbjct: 597 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643
Query: 682 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 716
+TT D+P T +AP P P P+
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678
Score = 90.1 bits (222), Expect = 7e-18
Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%)
Query: 171 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 227
++ A ++T+E A EPA E +P +SAP P P P P P
Sbjct: 301 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 354
Query: 228 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 287
P APT + + P + PTT P APK+ + +P P +
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 409
Query: 288 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 347
+ P P T+ PS P+TP+ P T S+ P T AP P P
Sbjct: 410 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
S T+T + P P+ P+ PAP P P P + +E + +
Sbjct: 460 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 463
T K+ P + PE L EKP A + PEE A + E
Sbjct: 517 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 569
Query: 464 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 523
+P P+ TPK P P PK P P TPK P P PK + G A ++
Sbjct: 570 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 625
Query: 524 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 578
P P + + A ++ P P G P P+ P+PT P+ +
Sbjct: 626 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 684
Query: 579 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 638
P AP + +P P A + L ++GP +T + P K
Sbjct: 685 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 731
Query: 639 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 696
+ P TP A +PK PAP T E PT TT EP I
Sbjct: 732 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 697 RTELASAPVPSPAPPPEA 714
++ S P S P P+A
Sbjct: 778 KSPDESTPELSAEPTPKA 795
Score = 61.2 bits (147), Expect = 3e-09
Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%)
Query: 233 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 289
PTP P + + + G + P T++ ++ + ++P P PP +
Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178
Query: 290 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 347
T L + + + G TS+ + + AP A P
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
+ A T+T L+ P P+ P+ PA P P P + + S P
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 283
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 465
T K+ P TK++P E A + P+E A + E P
Sbjct: 284 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 329
Query: 466 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 521
+S T P TPK P P PK P P TPK P P PK P+ +
Sbjct: 330 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 379
Query: 522 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 581
P P+ + A + TP P+ P+PT + PS +P
Sbjct: 380 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 428
Query: 582 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 637
AP P + P ++A T PK S P
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 469
Query: 638 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 697
P P P P +E PAP EP APT A TT EP
Sbjct: 470 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 518
Query: 698 TELASAPVPSPAPPPEAPRGL 718
T +AP P P L
Sbjct: 519 TPKETAPTTPKKLTPTTPEKL 539
Score = 60.5 bits (145), Expect = 6e-09
Identities = 64/245 (26%), Positives = 88/245 (35%), Gaps = 28/245 (11%)
Query: 197 SPPRAQSAPPEAAV--LPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254
+P P+AA P P P P P P APT + P TP +G
Sbjct: 567 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-----KETAPTTP--KGT 619
Query: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314
PTT K A L + P S+ P P+ G P +P+TP
Sbjct: 620 APTTLKEPAPTTPKKPAPKELAPTTTKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTP 677
Query: 315 RSSGPVT----ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLS-------AP 363
+ P T A ++L PAP+ P P AP+ AP + TST S + AP
Sbjct: 678 KEPAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAP 735
Query: 364 LRPS----ARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEE 419
P P+ PAP PP+ E + ++ T + P +
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795
Query: 420 TKNSP 424
+NSP
Sbjct: 796 LENSP 800
Score = 37.0 bits (84), Expect = 0.068
Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Query: 641 DEVPPTPGPIASGSPKTARVQEIRRFSTPA--PQPTAEPLAPTVLAPRAATTLDEPIWRT 698
+ P TP AS +PK I+ T P PT APT A TT EP T
Sbjct: 256 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315
Query: 699 ELASAPVPSPAPPPEAPRGLGASP 722
AP + P P + +P
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTP 339
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 99.0 bits (245), Expect = 1e-20
Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%)
Query: 154 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 208
G+ S + Q E+ + + T + LA+ P A G L +P P+ A
Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 318
Query: 209 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 268
+ P P P + S P P APT S P TP + PTTT P P
Sbjct: 319 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 368
Query: 269 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 328
K PAP + P P+ T P+ P +P+TP+ P T
Sbjct: 369 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 409
Query: 329 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 384
PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P +
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469
Query: 385 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 444
+E + P P TK++P ++P
Sbjct: 470 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 501
Query: 445 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 504
+S P +P + + P TPK P P PK P P TPK P P PK
Sbjct: 502 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 549
Query: 505 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 564
P A ++ P P + + + + TP P
Sbjct: 550 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598
Query: 565 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 622
P+PT L P+ P P A P P+AA P + TPK+
Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 648
Query: 623 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 681
P K + P TP A +PK ++ + P+ P + LAPT
Sbjct: 649 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695
Query: 682 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 716
+TT D+P T +AP P P P+
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730
Score = 90.1 bits (222), Expect = 7e-18
Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%)
Query: 171 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 227
++ A ++T+E A EPA E +P +SAP P P P P P
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 406
Query: 228 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 287
P APT + + P + PTT P APK+ + +P P +
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 461
Query: 288 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 347
+ P P T+ PS P+TP+ P T S+ P T AP P P
Sbjct: 462 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
S T+T + P P+ P+ PAP P P P + +E + +
Sbjct: 512 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 463
T K+ P + PE L EKP A + PEE A + E
Sbjct: 569 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 621
Query: 464 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 523
+P P+ TPK P P PK P P TPK P P PK + G A ++
Sbjct: 622 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 677
Query: 524 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 578
P P + + A ++ P P G P P+ P+PT P+ +
Sbjct: 678 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 736
Query: 579 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 638
P AP + +P P A + L ++GP +T + P K
Sbjct: 737 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 783
Query: 639 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 696
+ P TP A +PK PAP T E PT TT EP I
Sbjct: 784 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 697 RTELASAPVPSPAPPPEA 714
++ S P S P P+A
Sbjct: 830 KSPDESTPELSAEPTPKA 847
Score = 61.2 bits (147), Expect = 3e-09
Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%)
Query: 233 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 289
PTP P + + + G + P T++ ++ + ++P P PP +
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230
Query: 290 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 347
T L + + + G TS+ + + AP A P
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
+ A T+T L+ P P+ P+ PA P P P + + S P
Sbjct: 291 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 335
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 465
T K+ P TK++P E A + P+E A + E P
Sbjct: 336 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 381
Query: 466 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 521
+S T P TPK P P PK P P TPK P P PK P+ +
Sbjct: 382 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 431
Query: 522 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 581
P P+ + A + TP P+ P+PT + PS +P
Sbjct: 432 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 480
Query: 582 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 637
AP P + P ++A T PK S P
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 521
Query: 638 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 697
P P P P +E PAP EP APT A TT EP
Sbjct: 522 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 570
Query: 698 TELASAPVPSPAPPPEAPRGL 718
T +AP P P L
Sbjct: 571 TPKETAPTTPKKLTPTTPEKL 591
Score = 60.5 bits (145), Expect = 6e-09
Identities = 64/245 (26%), Positives = 88/245 (35%), Gaps = 28/245 (11%)
Query: 197 SPPRAQSAPPEAAV--LPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254
+P P+AA P P P P P P APT + P TP +G
Sbjct: 619 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-----KETAPTTP--KGT 671
Query: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314
PTT K A L + P S+ P P+ G P +P+TP
Sbjct: 672 APTTLKEPAPTTPKKPAPKELAPTTTKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTP 729
Query: 315 RSSGPVT----ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLS-------AP 363
+ P T A ++L PAP+ P P AP+ AP + TST S + AP
Sbjct: 730 KEPAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAP 787
Query: 364 LRPS----ARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEE 419
P P+ PAP PP+ E + ++ T + P +
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847
Query: 420 TKNSP 424
+NSP
Sbjct: 848 LENSP 852
Score = 37.0 bits (84), Expect = 0.068
Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Query: 641 DEVPPTPGPIASGSPKTARVQEIRRFSTPA--PQPTAEPLAPTVLAPRAATTLDEPIWRT 698
+ P TP AS +PK I+ T P PT APT A TT EP T
Sbjct: 308 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367
Query: 699 ELASAPVPSPAPPPEAPRGLGASP 722
AP + P P + +P
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTP 391
Score = 30.8 bits (68), Expect = 4.8
Identities = 78/395 (19%), Positives = 116/395 (29%), Gaps = 31/395 (7%)
Query: 334 PVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVP 393
P +P + + P PPS A+ T ++ S + + E S E + S
Sbjct: 69 PTSPPSSKKAP-PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127
Query: 394 AARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDAL 453
++ + R+ + K N + L + N + + P D
Sbjct: 128 SSSSSSSSSTIRK------IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 181
Query: 454 SLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP-PPVAPKPPSRGLLD 512
G + +F V T H T P + T P+ P+ PP + L
Sbjct: 182 GSGLDNGDFK--VTTPDTSTTQHNKVSTSPKIT--TAKPINPRPSLPPNSDTSKETSLTV 237
Query: 513 GLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS-PSPTPSL 571
+ + G E K S + +E T L P + PTP
Sbjct: 238 NKETTVETKETTTTNKQTSTDGKE---KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 294
Query: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPY 631
+ K P + P P P P TPK+ P
Sbjct: 295 ETTTK-GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA---------PT 343
Query: 632 QLKTAMFCFDEVPPT----PGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRA 687
K+A E PT P P P +E +T + T + APT A
Sbjct: 344 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403
Query: 688 ATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASP 722
TT EP T P P P +P
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 99.0 bits (245), Expect = 1e-20
Identities = 142/575 (24%), Positives = 201/575 (34%), Gaps = 115/575 (20%)
Query: 154 GQLSEVSGRGVQLFEQQRQRADSSTQE-LARVEPAA--MLNGEGLQSPPRAQSAPPE--A 208
G+ S + Q E+ + + T + LA+ P A G L +P P+ A
Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 359
Query: 209 AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 268
+ P P P + S P P APT S P TP + PTTT P P
Sbjct: 360 STTPKEPTPTTIKSA-PTTPKEPAPTTTKSA------PTTP--KEPAPTTTKEP-APTTP 409
Query: 269 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 328
K PAP + P P+ T P+ P +P+TP+ P T
Sbjct: 410 KE---------PAP-----TTTKEPAPTTTKSAPT-TPKEPAPTTPKKPAPTTPKE---- 450
Query: 329 PAPSRPVTPGGA-PEPPAPPSAA-AMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPS 384
PAP+ P P P+ PAP + A T+ +AP +P+ P+ PAP P P P +
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510
Query: 385 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 444
+E + P P TK++P ++P
Sbjct: 511 TKEPSPTTPK-------------------EPAPTTTKSAPTTT---------KEPAPTTT 542
Query: 445 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 504
+S P +P + + P TPK P P PK P P TPK P P PK
Sbjct: 543 KSAPTTPK-----------EPSPTTTKEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPK 590
Query: 505 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 564
P A ++ P P + + + + TP P
Sbjct: 591 EP-----------APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639
Query: 565 PSPTP--SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKA 622
P+PT L P+ P P A P P+AA P + TPK+
Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPA------PTTPKAAA--PNTPKEPAPTTPKEPA-- 689
Query: 623 LDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ-PTAEPLAPT 681
P K + P TP A +PK ++ + P+ P + LAPT
Sbjct: 690 -------PTTPK------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736
Query: 682 VLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPR 716
+TT D+P T +AP P P P+
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771
Score = 90.1 bits (222), Expect = 7e-18
Identities = 144/558 (25%), Positives = 200/558 (35%), Gaps = 77/558 (13%)
Query: 171 RQRADSSTQELARV---EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQ 227
++ A ++T+E A EPA E +P +SAP P P P P P
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKE--PAPTTTKSAP----TTPKEPAPTTPKKPAPTT 447
Query: 228 PGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS 287
P APT + + P + PTT P APK+ + +P P +
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTAPKKPAPT----TPKEPAPTT 502
Query: 288 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 347
+ P P T+ PS P+TP+ P T S+ P T AP P P
Sbjct: 503 PKEPAPT---TTKEPS-------PTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
S T+T + P P+ P+ PAP P P P + +E + +
Sbjct: 553 SP---TTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM-- 463
T K+ P + PE L EKP A + PEE A + E
Sbjct: 610 PTTPKET-APTTPKKLTPTTPE--KLAPTTPEKP----APTTPEELAPTTPEEPTPTTPE 662
Query: 464 QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG 523
+P P+ TPK P P PK P P TPK P P PK + G A ++
Sbjct: 663 EPAPTTPKAAAPN-TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT---APTTLK 718
Query: 524 IPEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----GLGP-RPRSPSPTPSLPPSWKYS 578
P P + + A ++ P P G P P+ P+PT P+ +
Sbjct: 719 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-PTT 777
Query: 579 PNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF 638
P AP + +P P A + L ++GP +T + P K
Sbjct: 778 PKGTAPTTLKEPAPTTPKKP-APKELAPTTTKGPTSTTSD--------KPAPTTPK---- 824
Query: 639 CFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP--IW 696
+ P TP A +PK PAP T E PT TT EP I
Sbjct: 825 --ETAPTTPKEPAPTTPK-----------KPAP-TTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 697 RTELASAPVPSPAPPPEA 714
++ S P S P P+A
Sbjct: 871 KSPDESTPELSAEPTPKA 888
Score = 61.2 bits (147), Expect = 3e-09
Identities = 113/501 (22%), Positives = 159/501 (31%), Gaps = 95/501 (18%)
Query: 233 PTPAPSIFNRSARPFTPG-LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP--PPFLSSQ 289
PTP P + + + G + P T++ ++ + ++P P PP +
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271
Query: 290 GPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP--APP 347
T L + + + G TS+ + + AP A P
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331
Query: 348 SAAAMTSTASIFLSAPLRPS-ARPEAPAPG-PGAPEPPSAREQRISVPAARTGILQEARR 405
+ A T+T L+ P P+ P+ PA P P P + + S P
Sbjct: 332 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIK----SAPT----------- 376
Query: 406 RGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQP 465
T K+ P TK++P E A + P+E A + E P
Sbjct: 377 --TPKE---PAPTTTKSAPTTPKEPAPTTTKEP-----APTTPKEPAPTTTKEPA----P 422
Query: 466 VGARSYKTLPH----VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASS 521
+S T P TPK P P PK P P TPK P P PK P+ +
Sbjct: 423 TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA----------PTTK 472
Query: 522 AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNI 581
P P+ + A + TP P+ P+PT + PS +P
Sbjct: 473 EPAPTTPK----------EPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPS-PTTPKE 521
Query: 582 RAPPPIAYNPLLS----PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAM 637
AP P + P ++A T PK S P
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP------------------- 562
Query: 638 FCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR 697
P P P P +E PAP EP APT A TT EP
Sbjct: 563 ----TTPKEPAPTTPKKPAPTTPKE------PAPTTPKEP-APTTTKKPAPTTPKEPAPT 611
Query: 698 TELASAPVPSPAPPPEAPRGL 718
T +AP P P L
Sbjct: 612 TPKETAPTTPKKLTPTTPEKL 632
Score = 60.5 bits (145), Expect = 6e-09
Identities = 64/245 (26%), Positives = 88/245 (35%), Gaps = 28/245 (11%)
Query: 197 SPPRAQSAPPEAAV--LPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQ 254
+P P+AA P P P P P P APT + P TP +G
Sbjct: 660 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-----KETAPTTP--KGT 712
Query: 255 RPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTP 314
PTT K A L + P S+ P P+ G P +P+TP
Sbjct: 713 APTTLKEPAPTTPKKPAPKELAPTTTKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTP 770
Query: 315 RSSGPVT----ATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLS-------AP 363
+ P T A ++L PAP+ P P AP+ AP + TST S + AP
Sbjct: 771 KEPAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTTKGPTSTTSDKPAPTTPKETAP 828
Query: 364 LRPS----ARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEE 419
P P+ PAP PP+ E + ++ T + P +
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888
Query: 420 TKNSP 424
+NSP
Sbjct: 889 LENSP 893
Score = 37.0 bits (84), Expect = 0.068
Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 2/84 (2%)
Query: 641 DEVPPTPGPIASGSPKTARVQEIRRFSTPA--PQPTAEPLAPTVLAPRAATTLDEPIWRT 698
+ P TP AS +PK I+ T P PT APT A TT EP T
Sbjct: 349 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408
Query: 699 ELASAPVPSPAPPPEAPRGLGASP 722
AP + P P + +P
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTP 432
Score = 30.8 bits (68), Expect = 4.8
Identities = 78/395 (19%), Positives = 116/395 (29%), Gaps = 31/395 (7%)
Query: 334 PVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVP 393
P +P + + P PPS A+ T ++ S + + E S E + S
Sbjct: 110 PTSPPSSKKAP-PPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168
Query: 394 AARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDAL 453
++ + R+ + K N + L + N + + P D
Sbjct: 169 SSSSSSSSSTIRK------IKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 222
Query: 454 SLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTP-PPVAPKPPSRGLLD 512
G + +F V T H T P + T P+ P+ PP + L
Sbjct: 223 GSGLDNGDFK--VTTPDTSTTQHNKVSTSPKIT--TAKPINPRPSLPPNSDTSKETSLTV 278
Query: 513 GLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS-PSPTPSL 571
+ + G E K S + +E T L P + PTP
Sbjct: 279 NKETTVETKETTTTNKQTSTDGKE---KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 335
Query: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPY 631
+ K P + P P P P TPK+ P
Sbjct: 336 ETTTK-GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAP-TTPKEPA---------PT 384
Query: 632 QLKTAMFCFDEVPPT----PGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRA 687
K+A E PT P P P +E +T + T + APT A
Sbjct: 385 TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444
Query: 688 ATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASP 722
TT EP T P P P +P
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 95.9 bits (237), Expect = 1e-19
Identities = 163/619 (26%), Positives = 220/619 (35%), Gaps = 106/619 (17%)
Query: 198 PPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPT 257
PP +A P A LPPSP P+A+P P P +P+ PS+ + P TP Q
Sbjct: 318 PPPDNAATPLPATLPPSP---PLATPLPLAPP--SPSAPPSLQTLPSPPATPPSQAPPSM 372
Query: 258 TTSVIFRP-----LAPKRANDSLGGLS----PAPPPFLSSQGPTPLPSFTSGVPSHAPVS 308
TT + P + P + SL S P+P S Q T L S T +H+ ++
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA-THSFLT 431
Query: 309 GSP--------------STPRSSGPVTATSSLYIPAP-----SRPVTPGGAPEPPAPPSA 349
SP STP S P+ A SL P S V+P +P P
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP--L 489
Query: 350 AAMTSTASIFLSAPLR----PSARPEAPAPGPGAPEPPSA--REQRISVPAARTGILQEA 403
A++S AS APL P ++ P PP++ ++P+ LQ A
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA 549
Query: 404 RRRGTRKQMFRP---------GKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALS 454
T + P +P PE S + P+A A + P L
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT--PPPQAPPALASPPLQGLP 607
Query: 455 LGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL 514
+ P A LP P PP P +PP TP P AP + LL
Sbjct: 608 SPPLSPLATPPPQAPPXLALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-- 662
Query: 515 VNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPS 574
A + P PP +Q + S + + P P PSP S P S
Sbjct: 663 ----APFSPPPSPP-VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 575 WKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLK 634
+P +APPP+A PL P P A+ + + + PR P L P L
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 635 TAMFCFDEVPPTPGPIASGSPKTARVQE------------------IRRFSTPAPQ---- 672
+ PP P A +P + + +TP PQ
Sbjct: 778 MSPLA---KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 834
Query: 673 --------PTAEPLAPTVLAPRAATT--LDEPIWRTELASAPVPSPAPPPEAPRGLGASP 722
P + P +PT+ APR T D + L A P P PPP SP
Sbjct: 835 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP------SRSP 888
Query: 723 SS--CGFQVARPRFSATRT 739
SS G +A SAT T
Sbjct: 889 SSTLSGPDLAGHSSSATST 907
Score = 90.5 bits (223), Expect = 5e-18
Identities = 154/603 (25%), Positives = 217/603 (35%), Gaps = 96/603 (15%)
Query: 170 QRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPG 229
+R RA + L R P+A + P ++ S+ E + PSP A+ R G
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSSASEHSTTEPSP-----AARRRPSAG 231
Query: 230 GGAPTPAPSIFNRSARPFT------PGLQGQRPTTTSVIFRP-------LAPKRANDSLG 276
GG PA + SA P + P +G P + +P L P +
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 277 GLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS---PSTPRSSGPVTATSSLYIPAPSR 333
+PA P SS TP PS T P P + + P+T S P+ L P+PS
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 334 PVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAP--------APGPGAPEPPSA 385
P + P PPA P + A S + + AP PS + P +P AP P A
Sbjct: 351 PPSLQTLPSPPATPPSQAPPSMTTPPMQAP--PSLQTIPPIQVPHSLTSPSLQAPPSPLA 408
Query: 386 REQRISVPAARTGILQEARR------RGTRKQMFRPGKEETKNSPNPEL---LSLVQNLD 436
+ + + LQ R T+ + P + + +P L LSL +
Sbjct: 409 LSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP 468
Query: 437 EKPRAGGAES--------GPEEDALSLGAEACN------FMQPVGARSYKTLPHVTPKTP 482
+ A S P + SL + + M P+ +S P + +TP
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL--QTP 526
Query: 483 PPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQ 542
P A T PP+ + P +AP PP + L + P P LQ L
Sbjct: 527 P--ASLTTPPL--ENLPSLAP-PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP 581
Query: 543 SRADRYVVEGTPGPGLGPRPRSP--SPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQA 600
TP P P SP PS P S +P +APP +A PL +P P A
Sbjct: 582 ETPSSI---ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638
Query: 601 ARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARV 660
+ L + P+A + L A F PP P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQ-----------APFSPPPSPPVQAP----------- 676
Query: 661 QEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPV-PSPAPPPEAPRGLG 719
FS PA P + P AP + + + AS P+ PS PPP+AP L
Sbjct: 677 -----FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 720 ASP 722
A P
Sbjct: 732 APP 734
Score = 78.2 bits (191), Expect = 3e-14
Identities = 132/542 (24%), Positives = 189/542 (34%), Gaps = 97/542 (17%)
Query: 200 RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT 259
+ A AA P+ + +PRP G+P P P P TP
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRP----PGSPRPPP--------PVTPAALRVLGAAG 51
Query: 260 SVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS--S 317
+V +PLA + GG+ A P P P+ ++G S P S P++ R +
Sbjct: 52 AVGRKPLAERA-----GGIGGATIP---ESAPRAGPTRSAGTSSRNPASRPPASGRGERA 103
Query: 318 GPVTATSSLYIPAPSRP---VTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPS----ARP 370
P TS + +P R PG + SA + AP R + AR
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA-TEAPKRSALSAGARR 162
Query: 371 EAPAPGPGAPEPPSAREQR-----ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 425
+ P PG P P AR R + +P G RK + E + P+
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV-SSASEHSTTEPS 221
Query: 426 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485
P +P AGG P +LS A + G + TP+ P
Sbjct: 222 PA-------ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-----RGTPRAPAHP 269
Query: 486 APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRA 545
+ P + PP V PP + L ++S P P
Sbjct: 270 SQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSP------------------ 309
Query: 546 DRYVVEGTPGPGLGPRPRSPSPTP-SLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTL 604
GT + P + +P P +LPP SP + P P+A SP P + +TL
Sbjct: 310 -----SGTKARPVPPPDNAATPLPATLPP----SPPLATPLPLAPP---SPSAPPSLQTL 357
Query: 605 PKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIR 664
P P ATP +A M P Q ++ +PP P + SP
Sbjct: 358 P-----SPPATPPS--QAPPSMTTPPMQAPPSL---QTIPPIQVPHSLTSPSLQAPPSPL 407
Query: 665 RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS----APVPSPAPPPEAPRGLGA 720
S + Q T +PT+ A + T+ + L S A P +PP +AP L A
Sbjct: 408 ALS--SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465
Query: 721 SP 722
SP
Sbjct: 466 SP 467
Score = 75.5 bits (184), Expect = 2e-13
Identities = 115/475 (24%), Positives = 159/475 (33%), Gaps = 78/475 (16%)
Query: 187 AAMLNGEGLQSPPRAQ----SAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNR 242
+A L L++PP APP PP P+ +A+P P P A P + +
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 243 SARPFT------------PGLQGQRPTTTSVIFRPLA---PKRANDSLGGLSPAPPPFLS 287
P P LQ S PLA P+ N L AP
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP----F 665
Query: 288 SQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAP---SRPVTPGGAPEPP 344
S P+P P+ PVS S + P + P A L +P S P++P P P
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 345 APPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEAR 404
APP AA P P++ P +P+ P PP + VP + L +
Sbjct: 726 APPPLAAPPLQVP-----PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS- 779
Query: 405 RRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLG----AEAC 460
+ +P + P L +L P A P + SL A
Sbjct: 780 ------PLAKPPPQAPPALATPPLQAL-----PSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 461 NFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKT---------------PPPVAPKP 505
PV A +P P +P AP+ PP P T PPP + P
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Query: 506 PSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP 565
S L ++S+ PE R G E A D + P R P
Sbjct: 889 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW----SRGP 944
Query: 566 SPTPSLPPSWKYSPNIRAPPPIAYNP--------LLSPFFPQAARTLPKAQSQGP 612
+P P +++ +P P P A P + P++A P A GP
Sbjct: 945 AP----PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 995
Score = 65.5 bits (158), Expect = 2e-10
Identities = 113/443 (25%), Positives = 160/443 (36%), Gaps = 89/443 (20%)
Query: 317 SGPVTATSSLYIPAPSRPVTPGGA-PEPPAPPSAAAMTSTASIFLSAPLRPSAR------ 369
+G T + P P PG P PP P+A + A PL A
Sbjct: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 370 -PE-APAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNP- 426
PE AP GP S+R PA+ G + + + PG+ P P
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
Query: 427 ELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPP-M 485
L + +E G A P+ ALS GA + TP TP P M
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGAR-------------RDTSGPTPGTPSPAM 176
Query: 486 APKTPPPMT----PKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKR 541
A ++ T P+ P P+PP+ G + + + S P P A+R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA----------ARR 226
Query: 542 QSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAA 601
+ A G GL RP S S + S P S R+ P +A
Sbjct: 227 RPSA---------GGGL-QRPASRSLSSSATP---LSSPARSGP--------------SA 259
Query: 602 RTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQ 661
R P+A + + PK G++AL +P Q+ + P GP++S SP
Sbjct: 260 RGTPRAPAHPSQPKPK-GLQAL-----RPPQVTPPR---KDAAPALGPLSS-SP------ 303
Query: 662 EIRRFSTPAPQPT-AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA 720
+TP+P T A P+ P AAT L + + + P+P P P AP L
Sbjct: 304 ----LATPSPSGTKARPVPPP---DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356
Query: 721 SPSSCGFQVARPRFSATRTGLQA 743
PS ++ S T +QA
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQA 379
Score = 52.4 bits (124), Expect = 2e-06
Identities = 63/210 (30%), Positives = 72/210 (34%), Gaps = 22/210 (10%)
Query: 186 PAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVAS---PRPFQPGGGAPTPAPSIFNR 242
P A L L PP APP A P LP+P AS PF P P +
Sbjct: 772 PPASLPMSPLAKPP--PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Query: 243 SARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVP 302
A P Q P + AP+R P P P S GP + G P
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRP--------PTPGPDTSVSGPRLTLALAPGPP 881
Query: 303 SHAPVSGSPSTPRSSGPVTATSSLYIPAP-------SRPVTPGGAPEPPAPPSAAAMTST 355
P S SPS+ S + SS P S P A PP AA +
Sbjct: 882 P--PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 939
Query: 356 ASIFLSAPLRPSARPEAPAPGPGAPEPPSA 385
S + PL P AP P P A P SA
Sbjct: 940 WSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 94.4 bits (233), Expect = 4e-19
Identities = 145/551 (26%), Positives = 191/551 (34%), Gaps = 117/551 (21%)
Query: 187 AAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASP---RPFQPGGGAPTPAPSIFNRS 243
A L G+Q P+ ++ E L P P +P++ P P P A +P
Sbjct: 416 AKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELP 475
Query: 244 ARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPS 303
A P L RP S PL+P L +PPP S +PL P
Sbjct: 476 ASPLPEALHLSRPLEES----PLSPPPEESPL-----SPPP--ESSPFSPLEESPLSPPE 524
Query: 304 HAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAP 363
+P S + TP S P S L P P++P P +PP A+ LS P
Sbjct: 525 ESPPSPALETPLS--PPPEASPLSPPFEESPLSPPPEELPTSPPPEASR-------LSPP 575
Query: 364 LRPSARPEAPAPGPGAPEPPSAR------EQRISVPAARTGIL--QEARRRG--TRKQMF 413
S P P +P P ++R E +S P + + EA R
Sbjct: 576 PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM 635
Query: 414 RPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKT 473
P EE+ SP PE V L P PEE LS
Sbjct: 636 SPPPEESPMSPPPE----VSRLSPLPVVSRLSPPPEESPLS------------------P 673
Query: 474 LPHVTPKTPPPMAPKTPPPM--TPKTPPP--VAPKPPSRGLLDGLVNGAASSAGIPEPPR 529
P +P +PPP A + PP +P +PPP PP L L + +PE P+
Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQ 733
Query: 530 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP--SPTPSLPPSWKYSPNIRAP--P 585
L R + GP L PRP P SP P P SP P
Sbjct: 734 LCPR-------------------SEGPHLSPRPEEPHLSPRPEEP---HLSPQAEEPHLS 771
Query: 586 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 645
P P L P+ P Q++GP +P QP +L + P
Sbjct: 772 PQPEEPCLCA-VPEEPHLSP--QAEGPHLSP------------QPEELHLS-------PQ 809
Query: 646 TPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPV 705
T P S P+ + +PQP L+P P + +E EL P+
Sbjct: 810 TEEPHLSPVPEEPCL---------SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPL 860
Query: 706 -PSPAPPPEAP 715
P P PPE P
Sbjct: 861 SPRPEKPPEEP 871
Score = 88.6 bits (218), Expect = 2e-17
Identities = 145/598 (24%), Positives = 205/598 (34%), Gaps = 126/598 (21%)
Query: 198 PPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNR--SARPFTPGLQG-- 253
PP A P LP SPLP + RP + +P P S + + PF+P +
Sbjct: 461 PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPL 520
Query: 254 ---QRPTTTSVIFRPLAPKRANDSLGGLSP-------APPPFLSSQGPTPLPSFTSGVPS 303
+ + + PL+P LSP +PPP P P S S P
Sbjct: 521 SPPEESPPSPALETPLSPP---PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 304 HAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAP 363
+P+S P S P A S L+ P P++P P +PP A+ LS P
Sbjct: 578 ESPMSPPPEESPMSPPPEA-SRLFPPFEESPLSPPPEESPLSPPPEASR-------LSPP 629
Query: 364 LRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS 423
S P P +P P +R + V + + +E+ P EE+ S
Sbjct: 630 PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP--------LSPPPEESPTS 681
Query: 424 PNPELLSLVQNLDEKPRAGGAESGP-----EEDALSLGAEACNFMQ-----PVGARSYKT 473
P PE L ++ P + E P E+ +SL E + + RS
Sbjct: 682 PPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG- 740
Query: 474 LPHVTPKTPPPMAPKTP--PPMTPKTPPP-VAPKPPSRGLLDGLVNGAASSAGIPEPPRL 530
PH++P+ P P P ++P+ P ++P+P L +PE P L
Sbjct: 741 -PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCL-----------CAVPEEPHL 788
Query: 531 --QGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP--SPTPS---------------L 571
Q G L + + + ++ T P L P P P SP P
Sbjct: 789 SPQAEGPHLSPQPE---ELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR 845
Query: 572 PPSWKYSPNIRAPP--PIAYNPLLSPFFPQAARTLPKAQSQG-PRATPKQGIKALDFMRH 628
P SP + PP P P P A LP G P +P G AL
Sbjct: 846 PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905
Query: 629 QPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLA---- 684
P +E+P +P S SP+ P P PL+P + A
Sbjct: 906 PPLSPLP-----EELPLSPSGEPSLSPQLM-----------PPDPLPPPLSPIITAAAPP 949
Query: 685 ----------------------PRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA 720
P AA L+ PI A+ P P PP P G+
Sbjct: 950 ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007
Score = 86.7 bits (213), Expect = 7e-17
Identities = 131/551 (23%), Positives = 190/551 (34%), Gaps = 82/551 (14%)
Query: 195 LQSPPRAQ--SAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQ 252
L PP A S P E + L P P P + P P +P P +P
Sbjct: 536 LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP--- 592
Query: 253 GQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPS 312
P S +F P + +PPP S P P S S P +P+S P
Sbjct: 593 ---PPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649
Query: 313 TPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA 372
R S P+ S L P P++P P +PP A+ LS P P P +
Sbjct: 650 VSRLS-PLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR-------LSPP--PEDSPTS 699
Query: 373 PAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLV 432
P P +P P + +S+P + +L P EE + P E
Sbjct: 700 PPP-EDSPASPPPEDSLMSLPLEESPLL--------------PLPEEPQLCPRSE----G 740
Query: 433 QNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTP-- 490
+L +P PEE LS AE PH++P+ P P
Sbjct: 741 PHLSPRPEEPHLSPRPEEPHLSPQAEE---------------PHLSPQPEEPCLCAVPEE 785
Query: 491 PPMTPKTP-PPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR----- 544
P ++P+ P ++P+P L S +PE P L + E QS
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP--VPEEPCLSPQPEESHLSPQSEEPCLS 843
Query: 545 ---ADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAA 601
+ ++ P L PRP P P P+ + P PPP P LSP + A
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF--PPP--GEPSLSPLLGEPA 899
Query: 602 RTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPI--ASGSPKTAR 659
+ P P P++ L L + D +PP PI A+ P +
Sbjct: 900 LSEPGEPPLSP--LPEE----LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSP 953
Query: 660 VQEIR-----RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEA 714
+ E+ + + P A P+ T ++P +P + P P P +
Sbjct: 954 LGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPAS 1013
Query: 715 PRGLGASPSSC 725
P + P C
Sbjct: 1014 PILMEPLPPQC 1024
Score = 85.1 bits (209), Expect = 2e-16
Identities = 144/564 (25%), Positives = 190/564 (33%), Gaps = 94/564 (16%)
Query: 197 SPPRAQSA---PPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 253
SPP +S PPEA+ L P P +P++ P P +P P + S P L
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPP----PEESPMSPPPEVSRLSPLPVVSRLSP 664
Query: 254 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPST 313
P S PL+P +PPP S P P S TS P +P S P
Sbjct: 665 --PPEES----PLSPPPEESPT-----SPPPEASRLSPPPEDSPTSPPPEDSPASPPPED 713
Query: 314 PRSSGPVTATSSLYIPAPS-------------RPVTPGGAPEPPAP---PSAA----AMT 353
S P+ + L +P RP P +P P P P A +
Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQ 773
Query: 354 STASIFLSAPLRPSARPEAPAPGPGAPEP------PSAREQRISVPAARTGILQEARRRG 407
+ P P P+A P +P+P P E +S P L
Sbjct: 774 PEEPCLCAVPEEPHLSPQAEGPHL-SPQPEELHLSPQTEEPHLS-PVPEEPCLSPQ---- 827
Query: 408 TRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVG 467
+ P EE SP PE L L++ P + E PEE E P G
Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPG 887
Query: 468 ARSYKTL---PHVT-PKTPP--------PMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLV 515
S L P ++ P PP P++P P ++P+ PP PP ++
Sbjct: 888 EPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAA 947
Query: 516 NGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSW 575
A S G E P G G+ + A +P P P P LPPS
Sbjct: 948 PPALSPLGELEYPF--GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS- 1004
Query: 576 KYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKT 635
SP + PI PL P +L S + +P AL
Sbjct: 1005 PGSP-VGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP----ALPL---------- 1049
Query: 636 AMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPI 695
VP PI K V + + +EP P L P A + L P+
Sbjct: 1050 ------SVPSPLSPIG----KVVGVSDEAELHEMETEKVSEPECPA-LEPSATSPLPSPM 1098
Query: 696 WRTELASAPVPSPAPPPEAPRGLG 719
S P PSPAP + GLG
Sbjct: 1099 GDL---SCPAPSPAPALDDFSGLG 1119
Score = 61.2 bits (147), Expect = 3e-09
Identities = 112/469 (23%), Positives = 150/469 (31%), Gaps = 109/469 (23%)
Query: 199 PRAQSAPPEAAVLPPSPLPAPVASPRPF-----QPGGGAP----------------TPAP 237
PR +APP PP P P + P +PG G P TP P
Sbjct: 2187 PRFPTAPP---TYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDP 2243
Query: 238 SIFNRS------ARPFTPGLQGQRPTTTSVIFRPLAPKRA-----NDSLGGLSPA-PPPF 285
+ R A P +PG+ G + + + P R + LG SP+ PP
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPN 2303
Query: 286 LSSQGPTPLPSFTSGVPSHAP-VSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPP 344
L + G+ P V +P TPR+S + L + P AP PP
Sbjct: 2304 LGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPP 2363
Query: 345 APPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEAR 404
+ P S + PL P RP+ P P PP + S P +R
Sbjct: 2364 SHPDIFRPGSYTDPYAQPPLTP--RPQPPPPESCCALPPRSLP---SDPFSRV------- 2411
Query: 405 RRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQ 464
P ++++S L PR AE A F
Sbjct: 2412 ----------PASPQSQSSSQSPL---------TPRPLSAE------AFCPSPVTPRFQS 2446
Query: 465 PVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI 524
P P + PP P++ P P PP P+PP G + + AG
Sbjct: 2447 P------------DPYSRPPSRPQSRDPFAPLHKPP-RPQPPEVAFKAGSLAHTSLGAGG 2493
Query: 525 PEPPRLQGRGGELFAKRQSRADRYVVE--------GTPGP-------GLG-PRPRSPSPT 568
G GEL AK S V GTP P +G P + P P
Sbjct: 2494 FPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ 2553
Query: 569 PSLPP------SWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQG 611
P LPP + P + P Y F P + P + S G
Sbjct: 2554 PGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602
Score = 56.2 bits (134), Expect = 1e-07
Identities = 137/553 (24%), Positives = 187/553 (33%), Gaps = 100/553 (18%)
Query: 211 LPPSP----LPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSV--IFR 264
+PP P P P A+P F G+PT P+ + SA F G P S +F
Sbjct: 2106 IPPQPGALGSPPPAAAPTIFI---GSPT-TPAGLSTSADGFLKPPAGSVPGPDSPGELFL 2161
Query: 265 PLAPKRA----NDSLGGLSPAPP--PFLSSQGPT--PLPSFTSGVPSHAPVSGSPSTPRS 316
L P+ + GL+PA P P + PT P PS T G P+ P+ G+ S P +
Sbjct: 2162 KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPMLGASSRPGA 2220
Query: 317 SGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPG 376
P + P P P+P P ++ + A PE+P G
Sbjct: 2221 GQP----GEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV------------PESPGVG 2264
Query: 377 PGAP-----EPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSL 431
G PP E R ++ + + + G F + EL +
Sbjct: 2265 GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTP 2324
Query: 432 -VQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTP 490
V PRA E P+ L L + +P A++ P P P + P
Sbjct: 2325 DVFKAPLTPRASQVE--PQSPGLGLRPQ-----EPPPAQALAPSPPSHPDIFRPGSYTDP 2377
Query: 491 PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVV 550
P TP P P P S L + + +P P+ Q R A+ +
Sbjct: 2378 YAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF-- 2435
Query: 551 EGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQ 610
P P + PR +SP P S PPS P R P + PL P PQ KA S
Sbjct: 2436 --CPSP-VTPRFQSPDPY-SRPPS---RPQSRDP----FAPLHKPPRPQPPEVAFKAGSL 2484
Query: 611 GPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPA 670
+ G A A +VP P SP T TP+
Sbjct: 2485 AHTSLGAGGFPA-------ALPAGPAGELHAKVPSGQPPNFVRSPGTGAF-----VGTPS 2532
Query: 671 PQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGA---------S 721
P P A + EP + PVP P PP P G+ +
Sbjct: 2533 PMRFTFPQA-----------VGEPSLK-----PPVPQPGLPP--PHGINSHFGPGPTLGK 2574
Query: 722 PSSCGFQVARPRF 734
P S + VA F
Sbjct: 2575 PQSTNYTVATGNF 2587
Score = 55.1 bits (131), Expect = 2e-07
Identities = 99/388 (25%), Positives = 135/388 (34%), Gaps = 57/388 (14%)
Query: 178 TQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGA-PTPA 236
T ++VEP + G Q PP AQ+ P+P + P F+PG P
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQAL-----------APSPPSHPDIFRPGSYTDPYAQ 2380
Query: 237 PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA--NDSLGGLSPAPPPFLSSQGP-TP 293
P P TP Q P + + P R+ +D + +P SSQ P TP
Sbjct: 2381 P--------PLTPRPQPPPPESCCAL-----PPRSLPSDPFSRVPASPQSQSSSQSPLTP 2427
Query: 294 LPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMT 353
P S SP TPR P + P P P P P PP A
Sbjct: 2428 RPL------SAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKA 2481
Query: 354 -STASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQM 412
S A L A P+A P PA A P + P + + R T Q
Sbjct: 2482 GSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQA 2541
Query: 413 FRPGKEETKNS-PNPELLSLVQNLDEKPRAGGAESGPEEDALSLG-AEACNFMQPVGARS 470
G+ K P P L P + GP +LG ++ N+ G
Sbjct: 2542 V--GEPSLKPPVPQPGL--------PPPHGINSHFGP---GPTLGKPQSTNYTVATG--- 2585
Query: 471 YKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRL 530
P +P P + ++P PP V P P G L L +GA+ +GI P
Sbjct: 2586 -NFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEK 2644
Query: 531 QGRGGELFAKRQSRADRYVVEGTPGPGL 558
+ G + A+ + GT PG+
Sbjct: 2645 REDPGTGMGSSLATAE---LPGTQDPGM 2669
Score = 49.3 bits (116), Expect = 1e-05
Identities = 115/477 (24%), Positives = 165/477 (34%), Gaps = 114/477 (23%)
Query: 192 GEGLQSPPRAQSAPPEAAVLPPSPLPA-PVASPRPFQPGGGAPTPAPSIFNRSARPFTPG 250
G L P P+ SP+P P SP+P + + P + S RP
Sbjct: 794 GPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCL---SPRPEESH 850
Query: 251 LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTP--LPSFTS-GVPSHAPV 307
L + PL+P+ P PP Q P P LP F G PS +P+
Sbjct: 851 LSPELEKP------PLSPR----------PEKPPEEPGQCPAPEELPLFPPPGEPSLSPL 894
Query: 308 SGSPSTPRSSGPVTATSSLYIPAPSR-PVTPGGAP---------EPPAPPSAAAMTSTAS 357
G P+ P + P P P++P G P +P PP + +T+ A
Sbjct: 895 LGEPALSEPGEPPLS------PLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948
Query: 358 IFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGK 417
LS P E P G +P E ++ P T I P
Sbjct: 949 PALS----PLGELEYPFGAKGDSDP----ESPLAAPILETPI--------------SPPP 986
Query: 418 EETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPH- 476
E P P ++ P + G+ GP L M+P+ + L H
Sbjct: 987 EANCTDPEPVPPMIL------PPSPGSPVGPASPIL---------MEPLPPQCSPLLQHS 1031
Query: 477 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLD--GLVNGAASSAGIPEPPRLQGRG 534
+ P+ PP + +PP + P P++P G+ D L PE P L+
Sbjct: 1032 LVPQNSPP-SQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSA 1090
Query: 535 --------GELFAKRQSRA-----------DRYVVEGTPGPGLGPRPRSPSPTP-SLPPS 574
G+L S A D ++G PG P P TP SL
Sbjct: 1091 TSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP---EPGQTPGSLASE 1147
Query: 575 WKYSPNIRAPPPIA-YNPLLSPFFPQAARTL----PKAQSQGPRA----TPKQGIKA 622
K SP + P +A P+ +P+ +T P + + PRA TP IK+
Sbjct: 1148 LKGSPVLLDPEELAPVTPM--EVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKS 1202
Score = 39.7 bits (91), Expect = 0.010
Identities = 106/461 (22%), Positives = 157/461 (34%), Gaps = 83/461 (18%)
Query: 155 QLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAP----PEAAV 210
Q ++ + QL +QQ+Q+ Q+ + + + L SP + Q P
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPA 4003
Query: 211 LPPSPLPAPVA-SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPK 269
P +P A P G T P++ + + + G T+ P
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPG 4063
Query: 270 RANDSLGG------LSPAPPPFLSS---QGPTPLPS---------FTSGVPSHAPVSGSP 311
SL G + P P P SS Q P LP T+G SH +
Sbjct: 4064 EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGS 4123
Query: 312 STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPE 371
S+ SS P L P+ S PG + P L P++ + P+
Sbjct: 4124 SSEASSVP----HLLAQPSVSLGDQPGSMTQNLLGPQQP--------MLERPMQNNTGPQ 4171
Query: 372 APAPGP---------GAPEPPSAREQRISV-------PAAR----------TGILQEARR 405
P PGP G P+ + R + P R +L + +
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231
Query: 406 RGTRKQMFRPGKEE--TKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM 463
+ ++ P +E T+ SP LL L P G ++GP ++ LGA
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFP---GPQTGPLQE---LGAGP---- 4281
Query: 464 QPVGARSYKTLPHVTPKTPPPMAP--KTPPPMTPKTP--PPVAPKPPSRGLLDGLVNGAA 519
+P G P T P + P TPPP +P+ P P P P S+ L A
Sbjct: 4282 RPQGPPRLPAPPGAL-STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQ-----LPTEAQ 4335
Query: 520 SSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGP 560
P P+ QG E R S A + + GLGP
Sbjct: 4336 LPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGP 4376
Score = 38.1 bits (87), Expect = 0.030
Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 18/130 (13%)
Query: 268 PKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPV-------SGSPSTPRSSGPV 320
P L G SP P Q LP +T + S + S +P P
Sbjct: 4838 PGGKEKGLEGKSPDTGPDWLKQFDAVLPGYT--LKSQLDILSLLKQESPAPEPPTQHSYT 4895
Query: 321 TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTAS----IFLSAPLRPSARPEAPAPG 376
S+L + S P PE P+PP + S AS + P P A P P+P
Sbjct: 4896 YNVSNLDVRQLSAP-----PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPL 4950
Query: 377 PGAPEPPSAR 386
P A P SAR
Sbjct: 4951 PLASSPESAR 4960
Score = 37.7 bits (86), Expect = 0.040
Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 662 EIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR--TE-LASAPVPSPAPPPEAPRGL 718
++R+ S P P+ + P P+ LAP A+ EP+ TE LA PVPSP P +P
Sbjct: 4902 DVRQLSAPPPEEPSPP--PSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959
Query: 719 GASP 722
P
Sbjct: 4960 RPKP 4963
Score = 35.4 bits (80), Expect = 0.20
Identities = 81/347 (23%), Positives = 106/347 (30%), Gaps = 48/347 (13%)
Query: 135 MELARAGSRASEGQ-GSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAA----M 189
+ L S GQ GSG + S V Q + S TQ L + M
Sbjct: 4105 VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPM 4164
Query: 190 LNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTP 249
N G Q PP+ LP + V R G A P + +
Sbjct: 4165 QNNTGPQ-PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ 4223
Query: 250 GLQGQRPTTTSVIFRPLAPKRA----NDSLGGLSPAPPPFLSSQGPT--PLPSFTSGVPS 303
L QR S R P + L GL P GP PL +G
Sbjct: 4224 ALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP 4283
Query: 304 HAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAP 363
P PR P A S+ + P P P +P+ P PS S+
Sbjct: 4284 QGP-------PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS-------- 4328
Query: 364 LRPSARPEAPAPGPGAP-------EPPSAREQRISVPAARTGILQE----------ARRR 406
+ + P PG P EPP R + A T + A +
Sbjct: 4329 -QLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
Query: 407 GTRKQMFRPGKEETKNS---PNPELLSLVQNLDEKPRAGGAESGPEE 450
+ PG + N P LS+ Q E+P A GA+S E
Sbjct: 4388 KPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKRE 4434
Score = 33.5 bits (75), Expect = 0.75
Identities = 72/352 (20%), Positives = 121/352 (34%), Gaps = 43/352 (12%)
Query: 199 PRAQSAPPEAAVLPPS----PLP-APVASPRPFQPGGGAPTPAPSIFNRSARPFTPG--- 250
P S P A LPP+ P P P P P + A A ++F++ P+ P
Sbjct: 4324 PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNL 4383
Query: 251 LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS 310
+ Q+P +S++ P + G + P Q P P +G
Sbjct: 4384 AETQKPEQSSLV-----PGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGE 4438
Query: 311 P------------STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASI 358
P + PRS L + T G+ A + + A +
Sbjct: 4439 PIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGL 4498
Query: 359 FLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKE 418
PS + +A A P P+P ++ + ++R + +E R + + + + K+
Sbjct: 4499 EQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRAS-EALLKQLKQ 4557
Query: 419 ETKNSPNPE-LLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHV 477
E P E ++ +L +G +G + + G+ A P G Y L
Sbjct: 4558 ELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGAL----PTGPDYYSQLLTK 4613
Query: 478 TPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPR 529
+ PP TPP P P + +VNG S + E P+
Sbjct: 4614 NNLSNPP------------TPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPK 4653
Score = 33.1 bits (74), Expect = 0.97
Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 29/138 (21%)
Query: 138 ARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQEL---ARVEPAAMLNGEG 194
ARAG+ +G+ G GG+ + G+ ++ D+ ++++ ++L E
Sbjct: 4824 ARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQES 4883
Query: 195 LQSPPRAQSA----------------PPEAAVLPPSPL-PAPVASPR------PFQPGGG 231
P Q + PPE PPSPL P+P + P P +P
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE 4943
Query: 232 APTPAP---SIFNRSARP 246
P P+P + SARP
Sbjct: 4944 PPVPSPLPLASSPESARP 4961
Score = 32.3 bits (72), Expect = 1.7
Identities = 65/303 (21%), Positives = 89/303 (29%), Gaps = 66/303 (21%)
Query: 127 DWDSPYLDMELARAGSRAS-----EGQGSGLGGQLSE----------VSGRGVQLFEQQR 171
D PYL ++ S E G+G+G L+ +SG E+QR
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681
Query: 172 QRA--------DSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAV------------- 210
QR + R E G PP + A P +
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAG 2741
Query: 211 ---------LPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSV 261
LPPS L P+ P F P P A P + + ++ S
Sbjct: 2742 TQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPP-----PATPSSMDVNSRQLVGGSQ 2796
Query: 262 IFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSS-GPV 320
F AP + L Q T S + + P + P R + G
Sbjct: 2797 AFYQRAPYPGSLP---LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSP 2853
Query: 321 TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAP 380
A S +P P PV P P P + + L P P PG G P
Sbjct: 2854 LAGISTRLPGPGEPV-----PGPAGPAQFIELRHN----VQKGLGPGG---TPFPGQGPP 2901
Query: 381 EPP 383
+ P
Sbjct: 2902 QRP 2904
Score = 31.6 bits (70), Expect = 2.8
Identities = 23/69 (33%), Positives = 28/69 (40%), Gaps = 10/69 (14%)
Query: 552 GTPGP--------GLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAART 603
G PGP G GPRP+ P P+ P + P + P P SP P+
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP--PPSSPQEPKRPSQ 4322
Query: 604 LPKAQSQGP 612
LP SQ P
Sbjct: 4323 LPSPSSQLP 4331
Score = 30.4 bits (67), Expect = 6.3
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 16/78 (20%)
Query: 560 PRPRSPSPTPS----LPPSWKYSPNIRAP-PPIAYNPLLSPF----FPQAARTLPKAQ-- 608
P P PSP PS P S P + P P+A P+ SP P++AR P+A+
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
Query: 609 -----SQGPRATPKQGIK 621
S+ PR +G++
Sbjct: 4969 EEGEDSRPPRLKKWKGVR 4986
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 92.4 bits (228), Expect = 1e-18
Identities = 120/431 (27%), Positives = 142/431 (32%), Gaps = 71/431 (16%)
Query: 185 EPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSA 244
+P + E L PP P A + PP PLP P P PG G P P P +A
Sbjct: 898 QPPPLQGTEMLPPPPPPL---PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPP--LPGAA 952
Query: 245 RPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSH 304
P P L G + P P G P PPP + P P P +G+P
Sbjct: 953 IPPPPPLPG-----AGIPLPPPLP-------GAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1000
Query: 305 APVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPL 364
P+ G+ P P IP P P+ G P PP P A P
Sbjct: 1001 PPLPGAGIPPPPPLPGAG-----IPPPP-PLPGAGIPPPPPLPGAG--------IPPPPP 1046
Query: 365 RPSA--RPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN 422
P A P P PG G P PP I P G G PG
Sbjct: 1047 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-------AGIPPPPPLPGAGIPPP 1099
Query: 423 SPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTP 482
P P + + P GA P G + G LP V P
Sbjct: 1100 PPLPGV-----GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
Query: 483 PPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGRGGELFAKR 541
PP+ PP P + P PP G+ G+ GIP PP L G G
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGV--GIPPPPPLPGVGIPPPPPLPGAG------- 1205
Query: 542 QSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQ-A 600
+ P PG+G P+P P LPP P PPP P PQ
Sbjct: 1206 -------IPPPPPLPGMG---IPPAPAPPLPP-----PGTGIPPPPLLPVSGPPLLPQVG 1250
Query: 601 ARTLPKAQSQG 611
+ TLP Q G
Sbjct: 1251 SSTLPTPQVCG 1261
Score = 80.9 bits (198), Expect = 4e-15
Identities = 137/514 (26%), Positives = 164/514 (31%), Gaps = 106/514 (20%)
Query: 213 PSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRAN 272
PSP P P PG G P P P PG+ +T++ P P
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPP--------PPLPGMTVPTLPSTAI---PQPP---- 900
Query: 273 DSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPS 332
L G PPP P PLP +G+P P+ G+ P P IP P
Sbjct: 901 -PLQGTEMLPPP------PPPLPG--AGIPPPPPLPGAGILPLPPLPGAG-----IPPP- 945
Query: 333 RPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSA--RPEAPAPGPGAPEPPSAREQRI 390
P PG A PP P A I L PL P A P P PG G P PP I
Sbjct: 946 -PPLPGAAIPPPPP------LPGAGIPLPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGI 997
Query: 391 SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEE 450
P G G PG P P + P GA P
Sbjct: 998 PPPPPLPG-------AGIPPPPPLPGAGIPPPPPLPG-----AGIPPPPPLPGAGIPPPP 1045
Query: 451 DALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGL 510
G + G LP PPP+ PP P + P PP G+
Sbjct: 1046 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1105
Query: 511 LDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPS 570
GIP PP L G G + P PG G P P P
Sbjct: 1106 ------------GIPPPPPLPGAG--------------IPPPPPLPGAGIPPPPPLPGAG 1139
Query: 571 LPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQP 630
+PP P + PPP PL P LP A P P GI P
Sbjct: 1140 IPPP-PPLPRVGIPPP---PPLPGAGIPPPP-PLPGAGIPPPPPLPGVGIP-------PP 1187
Query: 631 YQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAP--TVLAPRAA 688
L +PP P +G P + + PAP PL P T + P
Sbjct: 1188 PPLPGV-----GIPPPPPLPGAGIPPPPPLPGMGIPPAPAP-----PLPPPGTGIPPPPL 1237
Query: 689 TTLDEPIWRTELASAPVPSPAP----PPEAPRGL 718
+ P ++ S+ +P+P PP P GL
Sbjct: 1238 LPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGL 1271
Score = 62.4 bits (150), Expect = 2e-09
Identities = 133/528 (25%), Positives = 164/528 (31%), Gaps = 80/528 (15%)
Query: 230 GGAPTPAPSIFNRSARPFTPGLQ-GQRPTTTSVIFRPLAPKRANDSLGGLSPA------P 282
GG T P P PG + G + S I ++P+R + L P P
Sbjct: 752 GGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPP 811
Query: 283 PPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATS----SLYIPAP------- 331
PP P+ L S G P P + ++S + +S S IP+P
Sbjct: 812 PP------PSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865
Query: 332 SRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR-------PEAPAPGPGAPEPPS 384
S PG PP PP MT + P P + P P PG G P PP
Sbjct: 866 SSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP- 924
Query: 385 AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGA 444
+P A L G PG P P + P GA
Sbjct: 925 ------PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-----AGIPLPPPLPGA 973
Query: 445 ESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM--APKTPPPMTPKTPPPVA 502
P G + G LP PPP+ A PPP P P
Sbjct: 974 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1033
Query: 503 PKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRP 562
P P G+ AGIP PP L G G + P PG G P
Sbjct: 1034 PPLPGAGIPP---PPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPP 1087
Query: 563 RSPSPTPSLPPSWKYSPNIRAPPP-------IAYNPLLSPFFPQAARTLPKAQSQGPRAT 615
P P +PP P + PPP I P L LP A P
Sbjct: 1088 PPPLPGAGIPPP-PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Query: 616 PKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQP-T 674
P+ GI P L A +PP P +G P + + P P P
Sbjct: 1147 PRVGIP-------PPPPLPGA-----GIPPPPPLPGAGIPPPPPLPGV---GIPPPPPLP 1191
Query: 675 AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASP 722
+ P P A P+ + AP P P PPP G G P
Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP-PLPPP----GTGIPP 1234
Score = 47.4 bits (111), Expect = 5e-05
Identities = 43/135 (31%), Positives = 47/135 (34%), Gaps = 15/135 (11%)
Query: 184 VEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRS 243
+ P L G G+ PP P A + PP PLP P P PG G P P P +
Sbjct: 1151 IPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP--LPGA 1204
Query: 244 ARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPS 303
P P L G PL P G PPP L GP LP S
Sbjct: 1205 GIPPPPPLPGMGIPPAPA--PPLPPP-------GTGIPPPPLLPVSGPPLLPQVGSSTLP 1255
Query: 304 HAPVSGSPSTPRSSG 318
V G P SG
Sbjct: 1256 TPQVCGFLPPPLPSG 1270
Score = 43.9 bits (102), Expect = 6e-04
Identities = 91/362 (25%), Positives = 115/362 (31%), Gaps = 65/362 (17%)
Query: 377 PGAPE-PPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLV--- 432
PG P PP A + + ++ RR + +P + ++ P P LL
Sbjct: 764 PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQG 823
Query: 433 QNLDEKPRAGGAE--SGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTP 490
Q + P + E + E S +CN P LP + P P
Sbjct: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSP------PPLPCTESSSSMPGLGMVP 877
Query: 491 PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVV 550
PP PPP L G+ S IP+PP LQG L +
Sbjct: 878 PP-----PPP----------LPGMTVPTLPSTAIPQPPPLQGT-EMLPPPPPPLPGAGIP 921
Query: 551 EGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQ 610
P PG G P P P +PP P PPP PL P LP A
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPP-PPLPGAAIPPP---PPLPGAGIP-LPPPLPGAGIP 976
Query: 611 GPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPA 670
P P GI P L A +PP P +G P P
Sbjct: 977 PPPPLPGAGIP-------PPPPLPGA-----GIPPPPPLPGAGIP------------PPP 1012
Query: 671 PQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 730
P P A + P P A P L A +P P P P A G+ P G +
Sbjct: 1013 PLPGA-GIPPPPPLPGAGIPPPPP-----LPGAGIPPPPPLPGA--GIPPPPPLPGAGIP 1064
Query: 731 RP 732
P
Sbjct: 1065 PP 1066
Score = 37.4 bits (85), Expect = 0.052
Identities = 70/268 (26%), Positives = 95/268 (35%), Gaps = 55/268 (20%)
Query: 276 GGLSPAPPPFLSSQGPTPLPSFT------SGVPSHAPVSGSPSTPRSSGPVTATSSLYIP 329
G PA PP S P SG AP GSP T ++ ++
Sbjct: 228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAP--GSPDTEQALSALSDLPESLAA 285
Query: 330 AP---SRPVTPGGAP--EPPAPPSA--AAMTSTASIFLSAPLRPSARPEAPAPGPGAPEP 382
P +P +PGG P E P+ P+A AA S +S P A AP GA +
Sbjct: 286 EPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDT 345
Query: 383 PSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG 442
E+ A R PG+E PE+ ++ P+
Sbjct: 346 DEEGEEDAFEDAPRGS----------------PGEEWA-----PEV------GEDAPQRL 378
Query: 443 GAESGPEEDALSLGAEACNFMQPVGA---RSYKTLPHVTP-----KTPPPMAPKTPPPMT 494
G E PEE+A A A + A R +K P +TP T +P P +
Sbjct: 379 GEE--PEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQS 436
Query: 495 PKTPPPVAPKPP---SRGLLDGLVNGAA 519
P P + +P SRG L + AA
Sbjct: 437 PNQSPRIKRRPEPSLSRGSRTALASVAA 464
Score = 32.3 bits (72), Expect = 1.7
Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 182 ARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFN 241
A + P L G G+ P PP + PP PL PV+ P G + P P +
Sbjct: 1204 AGIPPPPPLPGMGIPPAPAPPLPPPGTGI-PPPPL-LPVSGPPLLPQVGSSTLPTPQVCG 1261
Query: 242 RSARPFTPGLQG 253
P GL G
Sbjct: 1262 FLPPPLPSGLFG 1273
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 88.2 bits (217), Expect = 3e-17
Identities = 115/465 (24%), Positives = 166/465 (35%), Gaps = 65/465 (13%)
Query: 157 SEVSGRGVQLFEQQRQRADSS----TQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLP 212
SE RG QL E + R +S T + + P + S P PP P
Sbjct: 578 SEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP 637
Query: 213 PSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRAN 272
P P P P P P Q A + AP S LQ + ++ P P +
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST---ITRLQNASQHSGALFKPPTPPVMQS 694
Query: 273 DSL--------GGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGP----- 319
S+ G+ P PPP P P P+ S + P +PS P+ S P
Sbjct: 695 QSVKPQILVPPNGVVPPPPP------PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK 748
Query: 320 ---VTATSSLYIPAPSRPVTPGGAPEPP-APP----SAAAMTSTASIFLSAPLRPSARPE 371
V + + P P P P AP PP APP + A TST ++ AP+ A P
Sbjct: 749 IHQVQHITQVAPPTPPPP-PPIPAPLPPQAPPKPLVTIPAPTSTKTV---APVVTQAAPP 804
Query: 372 APAPGPGAPEPPSAREQRISV----PAARTGILQEARRRGTRKQMFRPGKEETKNSPNPE 427
P P P PP+ ++ P+ T + ++Q F + SP P
Sbjct: 805 TPTP----PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPS 860
Query: 428 LLS-LVQNLDEKPRAGGAESGPEEDA-LSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485
++ + P ES P + ++ ++ ++ ++P +P PPP
Sbjct: 861 VVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP 920
Query: 486 A---------PKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR--- 533
P +P P P PPP A P + G SS G +PP R
Sbjct: 921 PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS 980
Query: 534 -----GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPP 573
G E ++ D V + TP G + P P+ PP
Sbjct: 981 IKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
Score = 71.6 bits (174), Expect = 2e-12
Identities = 102/409 (24%), Positives = 137/409 (33%), Gaps = 86/409 (21%)
Query: 343 PPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI--- 399
PP P +T + S PL P P P P P P PP Q S P+A +
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQ--SAPSAGSAAPMF 664
Query: 400 --------LQEARRRGTRKQMFRPGKEETKNSPN--PELLSLVQNLDEKPRAGGAESGPE 449
LQ A + +F+P S + P++L + P P
Sbjct: 665 VKYSTITRLQNASQHSGA--LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG 722
Query: 450 EDALSLGAEAC-----NFMQPVGARSYKTLPHVT---PKTPPPMAPKTPPPMTPKTPPP- 500
L C F P + H+T P TPPP P P P+ P+ PP
Sbjct: 723 SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP-PPPIPAPLPPQAPPKP 781
Query: 501 --VAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGL 558
P P S + +V AA P P AK+Q + +P
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP---------AKKQPAFPASYIPPSP---- 828
Query: 559 GPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQ 618
P P P P P+LP + PPP +P+ S Q A P P TP
Sbjct: 829 -PTPPVPVPPPTLPKQQSFCAK---PPPSPLSPVPS-VVKQIASQFP------PPPTPPA 877
Query: 619 GIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPL 678
M QP + P P +A SP + + P QP++ P+
Sbjct: 878 -------MESQPLK------------PVPANVAPQSPPAVKAK-------PKWQPSSIPV 911
Query: 679 -APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCG 726
+P P ++L P P P PAPPP P +P G
Sbjct: 912 PSPDFPPPPPESSLVFP------PPPPSPVPAPPPPPPPTASPTPDKSG 954
Score = 65.9 bits (159), Expect = 1e-10
Identities = 93/374 (24%), Positives = 130/374 (34%), Gaps = 85/374 (22%)
Query: 174 ADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPF------- 226
A +ST+ +A V A PP + A+ +PPSP PV P P
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSF 846
Query: 227 --QPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRAN------------ 272
+P +P PS+ + A F P PT ++ +PL P AN
Sbjct: 847 CAKPPPSPLSPVPSVVKQIASQFPPP-----PTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Query: 273 -----DSLGGLSP---APPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATS 324
S+ SP PPP S P P PS P P + SP+ +S P T
Sbjct: 902 PKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT- 960
Query: 325 SLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPS-----------ARPEAP 373
S+ +PGG PP P +++ S++ P RPS A +P
Sbjct: 961 -------SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSP 1013
Query: 374 A----PGPGA-PEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPEL 428
+ P P A P+P +++P G+LQ+ + GK+ P+P
Sbjct: 1014 SKETLPPPAAPPKPGKLNLSGVNLP----GVLQQGCVSAKAPVLSGRGKDSVVEFPSP-- 1067
Query: 429 LSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM--- 485
P P E L L ++ S T P V P P
Sbjct: 1068 ----------PSDSDFPPPPPETELPLPP-----IEIPAVFSGNTSPKVAVVNPQPQQWS 1112
Query: 486 ---APKTPPPMTPK 496
K PPP PK
Sbjct: 1113 KMSVKKAPPPTRPK 1126
Score = 65.1 bits (157), Expect = 2e-10
Identities = 130/548 (23%), Positives = 186/548 (33%), Gaps = 132/548 (24%)
Query: 202 QSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSV 261
Q APP PP P+PAP+ P +P P P + ++ P Q PT T
Sbjct: 757 QVAPPTPP--PPPPIPAPLPPQAPPKPLVTIPAPTST---KTVAPVVT--QAAPPTPTPP 809
Query: 262 IFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS--GVPSHAPVSGSPSTPR---S 316
+ P A K+ + P+PP P LP S P +P+S PS + S
Sbjct: 810 V--PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867
Query: 317 SGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA---- 372
P T P +PV AP+ P A +SI + +P P PE+
Sbjct: 868 QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF 927
Query: 373 ------PAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS--- 423
P P P P PP+A T + PGK+ +K S
Sbjct: 928 PPPPPSPVPAPPPPPPPTASP--------------------TPDKSGSPGKKTSKTSSPG 967
Query: 424 -----PNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVT 478
P P+ S +++ + GAE PE S+ + F P + S
Sbjct: 968 GKKPPPTPQRNSSIKS------SSGAEH-PEPKRPSVDSLVSKFTPPAESGS-------- 1012
Query: 479 PKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI--PEPPRLQGRGGE 536
P PPP AP P + L G+ G + P L GRG +
Sbjct: 1013 -------------PSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKD 1059
Query: 537 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYS-PNIRAPPPIAYN--PLL 593
VVE P P S S P PP + P I P + N P +
Sbjct: 1060 -----------SVVE-------FPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKV 1101
Query: 594 SPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG 653
+ PQ + + + P T + + + + + T +VP +P S
Sbjct: 1102 AVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSV 1161
Query: 654 SP-------KTARVQEIRRF-STPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPV 705
P +T + + I R S + AEP A T+D+ +
Sbjct: 1162 QPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTA----------TMDD-----------M 1200
Query: 706 PSPAPPPE 713
P PPPE
Sbjct: 1201 ALPPPPPE 1208
Score = 56.2 bits (134), Expect = 1e-07
Identities = 96/393 (24%), Positives = 135/393 (34%), Gaps = 119/393 (30%)
Query: 397 TGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLG 456
+ + EA +RGT+ + + E+ N P SLV L +P+
Sbjct: 574 SSVFSEAWKRGTQLEESSKARMESMNRP---YTSLVPPLSPQPK---------------- 614
Query: 457 AEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAP--KPPSRG----- 509
+ P T +P PPP P PPP P PPP P PS G
Sbjct: 615 -----IVTPY------TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPM 663
Query: 510 -----LLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGP----- 556
+ L N + S + P PP +Q + K Q V P P
Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQS----VKPQILVPPNGVVPPPPPPPPPP 719
Query: 557 -------GLGPRPRSPS------PTPSL------------PPSWKYSPNIRA--PPPIAY 589
L P P +PS P P L PP+ P I A PP
Sbjct: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP 779
Query: 590 NPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTP-- 647
PL++ P + +T+ +Q TP + P K F +PP+P
Sbjct: 780 KPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV---------PPAKKQPAFPASYIPPSPPT 830
Query: 648 -------------------GPIASGSPKTARVQEIRRFSTPAPQPTA---EPL--APTVL 683
P + SP + V++I P P P A +PL P +
Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV 890
Query: 684 APRAATTLD-EPIWRTELASAPVPSPAPPPEAP 715
AP++ + +P W+ +S PVPSP PP P
Sbjct: 891 APQSPPAVKAKPKWQP--SSIPVPSPDFPPPPP 921
Score = 41.6 bits (96), Expect = 0.003
Identities = 48/198 (24%), Positives = 70/198 (35%), Gaps = 29/198 (14%)
Query: 556 PGLGPRPR------SPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLP---- 605
P L P+P+ + P+P LPP P PPP PL S P A P
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666
Query: 606 -----KAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARV 660
+ Q+ + M+ Q + + + VPP P P +P +A
Sbjct: 667 YSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMA 726
Query: 661 QEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASA------PVPSPAPPPEA 714
Q PAP P P AP + + T++A P+P+P PP
Sbjct: 727 Q-----LKPAP---CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778
Query: 715 PRGLGASPSSCGFQVARP 732
P+ L P+ + P
Sbjct: 779 PKPLVTIPAPTSTKTVAP 796
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 87.8 bits (216), Expect = 3e-17
Identities = 138/571 (24%), Positives = 196/571 (34%), Gaps = 97/571 (16%)
Query: 200 RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT 259
+ A AA P+ + +PRP G+P P P P TP
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRP----PGSPRPPP--------PVTPAALRVLGAAG 51
Query: 260 SVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS--S 317
+V +PLA + GG+ A P P P+ ++G S P S P++ R +
Sbjct: 52 AVGRKPLAERA-----GGIGGATIP---ESAPRAGPTRSAGTSSRNPASRPPASGRGERA 103
Query: 318 GPVTATSSLYIPAPSRP---VTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPS----ARP 370
P TS + +P R PG + SA + AP R + AR
Sbjct: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA-TEAPKRSALSAGARR 162
Query: 371 EAPAPGPGAPEPPSAREQR-----ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 425
+ P PG P P AR R + +P G RK + E + P+
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV-SSASEHSTTEPS 221
Query: 426 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485
P +P AGG P +LS A + G + TP+ P
Sbjct: 222 PA-------ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-----RGTPRAPAHP 269
Query: 486 APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEP-PRLQGRGGELFAKRQSR 544
+ P + PP V PP + L ++S P P LQ +
Sbjct: 270 SQPKPKGLQALRPPQVT--PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHS 327
Query: 545 ADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTL 604
+ TP P L P P+PS PPS + P+ A PP L QA +
Sbjct: 328 SSLTCQLATPLP-LAP------PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSF 380
Query: 605 PKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTP------GPIASGSPKTA 658
+ P ATP +A + P Q PP+P P+A+ SP+
Sbjct: 381 LPSPPLSPLATPPP--QAPPALALPPLQ----------APPSPPASPPLSPLATPSPQAP 428
Query: 659 RVQEIR----RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPV--------- 705
+ FS P P P +P P + + LA+ P+
Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
Query: 706 ----PSPAPPPEAPRGLGASPSSCGFQVARP 732
PS PPP+AP L A P Q+A+P
Sbjct: 489 PPMSPSATPPPQAPPPLAAPP----LQLAKP 515
Score = 84.0 bits (206), Expect = 5e-16
Identities = 159/608 (26%), Positives = 217/608 (35%), Gaps = 109/608 (17%)
Query: 170 QRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPG 229
+R RA + L R P+A + P ++ S+ E + PSP A+ R G
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSSASEHSTTEPSP-----AARRRPSAG 231
Query: 230 GGAPTPAPSIFNRSARPFT------PGLQGQRPTTTSVIFRP-------LAPKRANDSLG 276
GG PA + SA P + P +G P + +P L P +
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 277 GLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSS---LYIPAPSR 333
+PA P SS TP PS + + S AP + P+TP SS ++ L P+PS
Sbjct: 291 DAAPALGPLSSSPLATPSPS--AALQSQAPPT-LPATPHSSSLTCQLATPLPLAPPSPSA 347
Query: 334 PVTPGGAPEPPAPPSAAAMTS--------TASIFLSAPLRPSARPEAPAPGPGAPEPPSA 385
P + P PPA P + A TS T S S PL P A P AP P PP
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALPP-- 404
Query: 386 REQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ---NLDEKPRAG 442
+ S PA+ P + +PN + L+Q + P
Sbjct: 405 LQAPPSPPAS---------------PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
Query: 443 GAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVA 502
S P +S A + P A P PP P +PP TPPP A
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLA--------APPLQVPPSPPASPPMSPSATPPPQA 501
Query: 503 PKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRP 562
P P + L + + PP ++ P P
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPP---------------------LQALPSPPASFPG 540
Query: 563 RSP-SPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIK 621
++P SP+ SLP S +P +APP +A L P P A+ TL Q PR P G
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL-----QAPRRPPTPG-- 593
Query: 622 ALDFMRHQPYQLKTAMFCFDEVPPTPGPIAS---------GSPKTARVQEIRRF-STPAP 671
D P +L A+ PP+ P ++ S T+ +E+R + S P
Sbjct: 594 -PDTSVSGP-RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
Query: 672 QPTAEPLAPTVLAP-RAATTLDEPIWRTELASAP-VPSPAPPPEAPRGLGASPSSCGFQV 729
A P LA A P AP P P PP P G++ C
Sbjct: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP---GSADGLCTIYE 708
Query: 730 ARPRFSAT 737
SAT
Sbjct: 709 TEGPESAT 716
Score = 49.3 bits (116), Expect = 1e-05
Identities = 67/271 (24%), Positives = 93/271 (34%), Gaps = 33/271 (12%)
Query: 480 KTPPPMAPK--TP-PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG-IPEPPRLQGRGG 535
+TP AP TP PP +P+ PPPV P V GAA + G P R G GG
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALR-------VLGAAGAVGRKPLAERAGGIGG 67
Query: 536 ELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSP 595
+ RA GT RP + PP+ SP P+ SP
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP----------GPVSSP 117
Query: 596 FFPQAARTLPKAQSQGPRATPKQGI---KALDFMRHQPYQLKTAMFCFDEVPPTPGPIAS 652
+G R + ++ + KA + + P TP P +
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
Query: 653 GSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPP 712
+ A + P P P+A P PT ++ ++ E + P P+ P
Sbjct: 178 RRSRAAGTE----VGLPRPAPSARPRPPTEGPRKSVSSASE-----HSTTEPSPAARRRP 228
Query: 713 EAPRGLGASPSSCGFQVARPRFSATRTGLQA 743
A GL S A P S R+G A
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSA 259
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 85.5 bits (210), Expect = 2e-16
Identities = 154/594 (25%), Positives = 207/594 (34%), Gaps = 111/594 (18%)
Query: 170 QRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPG 229
+R RA + L R P+A + P ++ S+ E + PSP A+ R G
Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSSASEHSTTEPSP-----AARRRPSAG 222
Query: 230 GGAPTPAPSIFNRSARPFT-PGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSS 288
GG PA + SA P + P G T P AP + P P +
Sbjct: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGT-----PRAPAHPSQ------PKPKGLQAL 271
Query: 289 QGPTPLPSFTSGVPSHAPVSGSP-STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPP 347
+ P P P+ P+S SP +TP S P P+PS P + P PPA P
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAP---------PSPSAPPSLQTLPSPPATP 322
Query: 348 SAAAMTS--------TASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI 399
+ A TS T S S PL P A P AP P PP + S PA+
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP-PALALPP--LQAPPSPPAS---- 375
Query: 400 LQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ---NLDEKPRAGGAESGPEEDALSLG 456
P + +PN + L+Q + P S P +S
Sbjct: 376 -----------PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 457 AEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVN 516
A + P A P PP P +PP TPPP AP P + L
Sbjct: 425 ATPPSQAPPSLA--------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476
Query: 517 GAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP-SPTPSLPPSW 575
+ + PP ++ P P ++P SP+ SLP S
Sbjct: 477 PPQAPPALATPP---------------------LQALPSPPASFPGQAPFSPSASLPMSP 515
Query: 576 KYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKT 635
+P +APP +A L P P A+ TL Q PR P G D P +L
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTL-----QAPRRPPTPG---PDTSVSGP-RLTL 566
Query: 636 AMFCFDEVPPTPGPIAS---------GSPKTARVQEIRRF-STPAPQPTAEPLAPTVLAP 685
A+ PP+ P ++ S T+ +E+R + S P A P LA
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626
Query: 686 -RAATTLDEPIWRTELASAP-VPSPAPPPEAPRGLGASPSSCGFQVARPRFSAT 737
A P AP P P PP P G++ C SAT
Sbjct: 627 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP---GSADGLCTIYETEGPESAT 677
Score = 80.5 bits (197), Expect = 5e-15
Identities = 133/552 (24%), Positives = 183/552 (33%), Gaps = 96/552 (17%)
Query: 200 RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTT 259
+ A AA P+ + +PRP G+P P P P TP
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRP----PGSPRPPP--------PVTPAALRVLGAAG 51
Query: 260 SVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSS-G 318
+V +PLA + GG+ A P P P+ TS P+ +P +S G
Sbjct: 52 AVGRKPLAERA-----GGIGGATIP---ESAPRAGPTRTSRPPASGRGERAPPAKNTSPG 103
Query: 319 PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPG 378
PV++ P+ G A + A +T + SA L AR + P PG
Sbjct: 104 PVSSPGRASGTTRPGPLGQKGL-RISAEETVARGKATEAPKRSA-LSAGARRDTSGPTPG 161
Query: 379 APEPPSAREQR-----ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ 433
P P AR R + +P G RK + E + P+P
Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV-SSASEHSTTEPSPA------ 214
Query: 434 NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVG--ARSYKTLP-HVTPKTPPPMAPKTP 490
+P AGG P +LS A + G AR P H + P + P
Sbjct: 215 -ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 273
Query: 491 PPMTP-----------------KTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 533
P +TP TP P AP PS S +P PP
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS---------APPSLQTLPSPPATP-- 322
Query: 534 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLL 593
+ S + P P L P +P P PP+ P ++APP +P L
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSP---LATPPPQAPPALALPP-LQAPPSPPASPPL 378
Query: 594 SPF---FPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPI 650
SP PQA L Q P + P P Q + V P+ P
Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPS----------PPVQAPFSPPASPPVSPSATPP 428
Query: 651 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 710
+ P A P P + P++P+ P A LA+ P+ P
Sbjct: 429 SQAPPSLAAPP----LQVPPSPPASPPMSPSATPPPQAP--------PPLAAPPLQLAKP 476
Query: 711 PPEAPRGLGASP 722
PP+AP L P
Sbjct: 477 PPQAPPALATPP 488
Score = 47.0 bits (110), Expect = 7e-05
Identities = 72/273 (26%), Positives = 94/273 (34%), Gaps = 46/273 (16%)
Query: 480 KTPPPMAPK--TP-PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAG-IPEPPRLQGRGG 535
+TP AP TP PP +P+ PPPV P V GAA + G P R G GG
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALR-------VLGAAGAVGRKPLAERAGGIGG 67
Query: 536 ELFAKRQSRADRYVVEGTPGPGLGPR-PRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLS 594
+ RA P G G R P + + +P S + P P+ L
Sbjct: 68 ATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 127
Query: 595 PFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGS 654
AR KA R+ G + D PTP G+
Sbjct: 128 SAEETVAR--GKATEAPKRSALSAGARR------------------DTSGPTP-----GT 162
Query: 655 PKTARVQEIRRFST----PAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 710
P A + R T P P P+A P PT ++ ++ E + P P+
Sbjct: 163 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE-----HSTTEPSPAARR 217
Query: 711 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQA 743
P A GL S A P S R+G A
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 83.2 bits (204), Expect = 8e-16
Identities = 138/582 (23%), Positives = 204/582 (35%), Gaps = 89/582 (15%)
Query: 202 QSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPA----PSIFNRSARPFTPGLQGQRPT 257
Q+ P P S LP+ S P G P A P++ N + Q R
Sbjct: 1261 QAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDG 1320
Query: 258 TTSVIFRPLAPKRANDSLG---GLSPAP---------PPFLSSQGPTPLPSFTSGVPS-- 303
T V PLAP S G L+P P P +++ P P P+ +
Sbjct: 1321 LTPV--PPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLV 1378
Query: 304 HAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAP 363
H+P ++ + P+T +S L++P+ P P + P A+ ++ST S+ LS+
Sbjct: 1379 HSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSS 1438
Query: 364 LRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS 423
L S PAP P + ++V A+ +L S
Sbjct: 1439 LPISVPTTLPAPASAPLTIPISAP--LTVSASGPALL---------------------TS 1475
Query: 424 PNPELLSLVQNLDEKPRAGGAESGPEEDALSLG---AEACNFMQPVG-----ARSYKTLP 475
P L +V P + + P AL+LG A + + Q G A + +P
Sbjct: 1476 VTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP 1535
Query: 476 HVTPKTPPPMAPKTPPPMTPKTPPPVAPKP-------------PSRGLLDGLVNGAASSA 522
+ P +P P +P P AP P S+ L L AA
Sbjct: 1536 GLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQT 1595
Query: 523 GI----PEPPRL-------QGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSL 571
I P PP + A Q+ TPG L P+PTP L
Sbjct: 1596 AILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVL 1655
Query: 572 PPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPY 631
PS S P P+ +PL SP Q P ++P Q + P+
Sbjct: 1656 APS---STQTMLPAPVP-SPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711
Query: 632 QLKT-AMFCFDEVPPTPGPIAS--GSPKTARVQEIRRFSTPAPQPTAEPLAPT-----VL 683
+T ++ + PTP S P Q + P P A P+ P L
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP-PLAPASPVGPAPAHTLTL 1770
Query: 684 APRAAT-TLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSS 724
AP +++ +L P L +P P P P A + L +P+S
Sbjct: 1771 APASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAS 1812
Score = 77.8 bits (190), Expect = 3e-14
Identities = 143/601 (23%), Positives = 203/601 (33%), Gaps = 84/601 (13%)
Query: 183 RVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPL-PAPVASPRPFQPGGGAPTPA----- 236
R +P M LQ P+ + P +PL P PV P P PTP
Sbjct: 986 RPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPP-PGPELSAQPTPGPVPQV 1044
Query: 237 -PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLP 295
P+ SA P P L V+ PL P + SL + P+P LS P P
Sbjct: 1045 LPASLMVSASPAGPPLIPASRPPGPVLLPPLQPN--SGSLPQVLPSPLGVLSGTSRPPTP 1102
Query: 296 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 355
+ + APV SP+ P S SSL P V PG PP+AA TST
Sbjct: 1103 TLSLKPTPPAPVRLSPAPPPGS------SSLLKPL---TVPPGYT----FPPAAATTTST 1149
Query: 356 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRP 415
+ + PAP P + + + +P+ + + R
Sbjct: 1150 TT-------ATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAG 1202
Query: 416 GKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDA---LSLGAEACNFMQPVGARSYK 472
G + L+L + A G + + +S G + QP ++
Sbjct: 1203 GSKPLTFQIQGNKLTLT-GAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQP----AHV 1257
Query: 473 TLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQG 532
L TP P TP + P + P P P L +A P +
Sbjct: 1258 ALIQAVAPTPGP----TPVSVLPSSTPSTTPAPTGLSL--------PLAANQVPPTMVNN 1305
Query: 533 RGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS--------PTPSLPPSWKYSPNI--- 581
G RQ+ D TP P L P PR PS P P+L P +P +
Sbjct: 1306 TGVVKIVVRQAPRDGL----TPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTA 1361
Query: 582 RAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFD 641
RAP P L+ P P+ + P A P L P + M +
Sbjct: 1362 RAPMPTP--TLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPN 1419
Query: 642 EVP-------PTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEP 694
P P++S P + S P P + PL + P T++ P
Sbjct: 1420 SSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPP 1479
Query: 695 IWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQV---ARPRFSATRTGLQAHVWRPGAG 751
+ APV AP P + GASPS+ + P S+++T + P +
Sbjct: 1480 L-------APVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSS 1532
Query: 752 H 752
H
Sbjct: 1533 H 1533
Score = 76.3 bits (186), Expect = 1e-13
Identities = 135/549 (24%), Positives = 185/549 (33%), Gaps = 77/549 (14%)
Query: 198 PPRAQSAPPEA----AVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 253
PP A + P + AVL P P P P P AP P P++ RP +
Sbjct: 1325 PPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTL----VRPLLKLVHS 1380
Query: 254 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPST 313
P S AP + L S P P + P P+P+ + P +PVS + S
Sbjct: 1381 PSPEV-SASAPGAAPLTISSPLHVPSSLPGP---ASSPMPIPNSS---PLASPVSSTVSV 1433
Query: 314 PRSSG-PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA 372
P SS P++ ++L PA + P AP + A +TS ++ PL P P A
Sbjct: 1434 PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTS-----VTPPLAPVV-PAA 1487
Query: 373 PAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLV 432
P P AP S +++ A L ++ G P +S P L S V
Sbjct: 1488 PGPPSLAPSGASPSASALTLGLATAPSLSSSQTPG------HPLLLAPTSSHVPGLNSTV 1541
Query: 433 QNLDEKPRA-GGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPP 491
A + P A + + + P + S + P P A P
Sbjct: 1542 APACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPS 1601
Query: 492 PMTPKTPPPV-APKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVV 550
P P P PV AP P + +L A+S +P G L + A
Sbjct: 1602 PAPPLAPLPVLAPSPGAAPVL------ASSQTPVPVMAPSSTPGTSLASASPVPA----- 1650
Query: 551 EGTPGPGLGPRPRS---PSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKA 607
P P L P P+P PS PS + + P +A P L P +L
Sbjct: 1651 ---PTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALA--PTLGGSSPSQTLSLGTG 1705
Query: 608 QSQGPRATPKQGIKALDFMRHQPYQL----------KTAMFCFDEVPP------------ 645
QGP T + + P Q T PP
Sbjct: 1706 NPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPA 1765
Query: 646 ---TPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTEL-- 700
T P +S + A +PAP PT P A LA A+T + L
Sbjct: 1766 HTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVV 1825
Query: 701 -ASAPVPSP 708
AS P P
Sbjct: 1826 SASGAAPLP 1834
Score = 66.2 bits (160), Expect = 1e-10
Identities = 127/556 (22%), Positives = 186/556 (33%), Gaps = 94/556 (16%)
Query: 199 PRAQSAPPEAAVLP-------PSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGL 251
P ++ P AA L PS LP P +SP P +P S + P + L
Sbjct: 1383 PEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTV---SVPLSSSL 1439
Query: 252 QGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSP 311
PTT P A+ L + + P +S+ GP L S T + P + P
Sbjct: 1440 PISVPTT--------LPAPASAPL-TIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGP 1490
Query: 312 STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARP- 370
+ SG + S+L + + P + + P P A TS+ L++ + P+ P
Sbjct: 1491 PSLAPSGASPSASALTLGLATAPSL--SSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPV 1548
Query: 371 -----EAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN 425
+P P AP P A+ ++ ++ + L M P SP
Sbjct: 1549 LVPASALASPFPSAPNPAPAQASLLAPASSASQALAT-----PLAPMAAPQTAILAPSPA 1603
Query: 426 PELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485
P L L L P A + + + + A P P +
Sbjct: 1604 PPLAPL-PVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASP-------VPAPTPVL 1655
Query: 486 APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRA 545
AP + M P P P P S L L A + G P + G Q
Sbjct: 1656 APSSTQTMLPAPVPSPLPSPASTQTL-ALAPALAPTLGGSSPSQTLSLG---TGNPQGPF 1711
Query: 546 DRYVVEGTPGPGLGPRPR---SPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAAR 602
+ TP L P P S +P P L P+ S + PP+A SP P A
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLS--LAPAPPLA---PASPVGPAPAH 1766
Query: 603 TLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQE 662
TL A A+ + A P ++T +P P+ + P A+
Sbjct: 1767 TLTLAP-----ASSSASLLA-------PASVQTLTL-------SPAPVPTLGPAAAQTLA 1807
Query: 663 IRRFSTPAPQPTAEPLA---------PTVLAPRAATTLDEPIWRTELASAPVP------- 706
+ ST +P A L P + R + DEP T + P P
Sbjct: 1808 LAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSF 1867
Query: 707 -------SPAPPPEAP 715
P PPP +P
Sbjct: 1868 GGPRPRRQPPPPPRSP 1883
Score = 64.3 bits (155), Expect = 4e-10
Identities = 133/496 (26%), Positives = 164/496 (33%), Gaps = 139/496 (28%)
Query: 199 PRAQSAPPEAAVLPPSP----LPAPVASPRPFQPGGGAP------TPAPSIFNRSARPFT 248
P A A P+ A+L PSP P PV +P P G AP TP P + A T
Sbjct: 1586 PLAPMAAPQTAILAPSPAPPLAPLPVLAPSP----GAAPVLASSQTPVPVM----APSST 1637
Query: 249 PGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGV---PSHA 305
PG + LAP L PAP P P P P+ T + P+ A
Sbjct: 1638 PGTSLASASPVPAPTPVLAPSSTQTML----PAPVP-----SPLPSPASTQTLALAPALA 1688
Query: 306 PVSG--SPS------TPRSSGPVTATSSLYIPAPSRPVTPGG----APEPPAPPSAAAMT 353
P G SPS T GP + PA S TP AP PP P T
Sbjct: 1689 PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGP-----T 1743
Query: 354 STASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMF 413
T S+ + PL P A P PAP P++ + PA+ +
Sbjct: 1744 QTLSLAPAPPLAP-ASPVGPAPAHTLTLAPASSSASLLAPAS------------VQTLTL 1790
Query: 414 RPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKT 473
P T + L+L A + P A SL A P+
Sbjct: 1791 SPAPVPTLGPAAAQTLAL---------APASTQSPASQASSLVVSASG-AAPLPVTMVSR 1840
Query: 474 LPHVTPKTPPPMAPKTPPPMTPKTP-------PPVAPKPPSRG--LLDGLVNGAASSAGI 524
LP V+ P + ++ PP P T P P PP R LD L
Sbjct: 1841 LP-VSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSL---------- 1889
Query: 525 PEPPRLQGRGGEL---FAKRQSRADRYVVEGT--------PGPGLGP-RPRSPSPTPSLP 572
E R + R L F ++ V GT P P P PRSP PS P
Sbjct: 1890 -EEKRKRQRSERLERIFQLSEAHGALAPVYGTEVLDFCTLPQPVASPIGPRSPG--PSHP 1946
Query: 573 PSWKYS----------------------------PNIRAPPPIAY----NPLLSPFFPQA 600
W Y+ P + APPP + P L+P QA
Sbjct: 1947 TFWTYTEAAHRAVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLHACHPPPWLAP--RQA 2004
Query: 601 ARTLPKAQSQGPRATP 616
A A PRA P
Sbjct: 2005 AFQEQLASELWPRARP 2020
Score = 50.8 bits (120), Expect = 5e-06
Identities = 144/607 (23%), Positives = 201/607 (33%), Gaps = 134/607 (22%)
Query: 183 RVEPAAMLNGEGLQSP---PRAQSAPPEAAVLP------------PSPLPAP---VASP- 223
R+ PA L P P + PP AA P+P PAP + SP
Sbjct: 1115 RLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPD 1174
Query: 224 -RPFQPGG--------GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLA-----PK 269
+ P G + P ++P T +QG + T T R LA P
Sbjct: 1175 MQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPL 1234
Query: 270 RAND----SLGGL-----SPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPV 320
+ N S GG PA + + PTP P+ PVS PS+ S+ P
Sbjct: 1235 QRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPT---------PVSVLPSSTPSTTP- 1284
Query: 321 TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPE---APAPGP 377
A + L +P + V PP+ T I + R P APAP P
Sbjct: 1285 -APTGLSLPLAANQV----------PPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRP 1333
Query: 378 GAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDE 437
+ P+ R P G L R M P P L+ + L
Sbjct: 1334 PSSGLPAVLNPR---PTLTPGRLPTPTLGTARAPM-----------PTPTLVRPLLKLVH 1379
Query: 438 KPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKT 497
P PE A + GA P+ S +LP P + P P + P +P +
Sbjct: 1380 SP-------SPEVSASAPGAAPLTISSPLHVPS--SLPG--PASSPMPIPNSSPLASPVS 1428
Query: 498 PPPVAPKPPSRGLLDGLVNGAASSAGIPEP---PRLQGRGGELFAKRQSRADRYVVEGTP 554
P S + A +SA + P P G + VV P
Sbjct: 1429 STVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP 1488
Query: 555 GP-GLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQ-GP 612
GP L P SPS + +L +P++ + + LL+P + +P S P
Sbjct: 1489 GPPSLAPSGASPSAS-ALTLGLATAPSLSSSQTPGHPLLLAP----TSSHVPGLNSTVAP 1543
Query: 613 RATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ 672
+P L A P P P + + A ++ A Q
Sbjct: 1544 ACSPV---------------LVPASALASPFPSAPNPAPAQASLLAP-------ASSASQ 1581
Query: 673 PTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARP 732
A PLAP + AP+ A LA +P P AP P GA+P Q P
Sbjct: 1582 ALATPLAP-MAAPQTAI----------LAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVP 1630
Query: 733 RFSATRT 739
+ + T
Sbjct: 1631 VMAPSST 1637
Score = 48.5 bits (114), Expect = 2e-05
Identities = 97/432 (22%), Positives = 156/432 (36%), Gaps = 60/432 (13%)
Query: 146 EGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAP 205
E +G G G + S +G G ++ + + ++ A +G P +
Sbjct: 2360 EEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQ 2419
Query: 206 PEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRP 265
+ PP PA PRP AP P P+ SA P L P S
Sbjct: 2420 TRSTTTPPRCSPARERVPRP------APRPRPT--PASAPAAIPALV---PVPVSAPVPI 2468
Query: 266 LAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSS 325
AP + P+PPP P+ +P +S P+ P P + P T
Sbjct: 2469 SAPNPITILPVHILPSPPP------PSQIPPCSS--PACTPPPACTPPPAHTPPPAQTC- 2519
Query: 326 LYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSA 385
+ PS P+ G PP+ P +A++T+ L RPEA P S
Sbjct: 2520 --LVTPSSPLLLG----PPSVPISASVTN---------LPLGLRPEAELCAQALASPESL 2564
Query: 386 REQRISVPAARTGILQEARRRG---TRKQMFRPGKEETKNSPNPELLSL----VQNLDEK 438
+ SV ++ T L + ++ ++ +P+ L+L + N E+
Sbjct: 2565 --ELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQ 2622
Query: 439 PRAGGAESG-----PEEDALSLGAEACNFMQ-PVGARSYKTLPHVTPKTPPPMAPKTPPP 492
AE PE + L L N ++ P A S + P P A +T
Sbjct: 2623 EAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDE------PLQEPLEADRTSEE 2676
Query: 493 MTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYV-VE 551
+T P +P+ P + + + SS+ P +G +R++ AD + +
Sbjct: 2677 LTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSP---EGPSPARPPRRRTSADVEIRGQ 2733
Query: 552 GTPGPGLGPRPR 563
GT PG P P+
Sbjct: 2734 GTGRPGQPPGPK 2745
Score = 42.7 bits (99), Expect = 0.001
Identities = 71/277 (25%), Positives = 100/277 (36%), Gaps = 51/277 (18%)
Query: 296 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRP-----------VTPGGAPEPP 344
S + G PS +SG S+P GP A S +P P + VT GG+PE
Sbjct: 2785 SASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPE-- 2842
Query: 345 APPSAAAMTSTASIFLSAPLRPSARPEAPA-PGPGAPEPPSAREQRIS-----VPAARTG 398
A + T RP + +PA G G E PS+ + + VP T
Sbjct: 2843 -NGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETL 2901
Query: 399 ILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAE 458
I+ + +P + + PNP LLS V EK R G P+ L +
Sbjct: 2902 IVADPVLEPQLIPGPQPLGPQPVHRPNP-LLSPV----EKRRRG---RPPKARDLPIPGT 2953
Query: 459 ACNFMQPVGARSYKTLPHVTPKTP-PPM--------------------APKTPPPMTPKT 497
+ + PH +P TP PP+ PK PK
Sbjct: 2954 ISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKN 3013
Query: 498 PPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRG 534
PP +P+P +LD S G+ + QG+G
Sbjct: 3014 PP--SPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQG 3048
Score = 35.8 bits (81), Expect = 0.15
Identities = 96/434 (22%), Positives = 132/434 (30%), Gaps = 119/434 (27%)
Query: 184 VEPAAMLNGEGLQSPPRAQSAP----PEAAVLPPS-------PLPAPVASPRPFQPGGGA 232
+E ++ NG+ ++P A+ PE LP LP AS P Q
Sbjct: 2611 LEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQE---- 2666
Query: 233 PTPAPSIFNRSARPFTPGLQGQRPT--TTSVIFRPLAPKRANDSLGGLSPAPPPFLSS-- 288
P A TP ++P T+ + P A S G SPA PP +
Sbjct: 2667 PLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSA 2726
Query: 289 -------------QGPTP-----LP------------------------SFTSGVPSHAP 306
Q P P LP + GV +
Sbjct: 2727 DVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSA 2786
Query: 307 VSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRP 366
GSPS SGP SS I P P PP P A
Sbjct: 2787 SPGSPSVRSMSGP---ESSPPIGGPCEAAPSSSLPTPPQQPFIA---------------- 2827
Query: 367 SARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNP 426
E G G+PE I+ PA + RRRG RP K+ +
Sbjct: 2828 RRHIELGVTGGGSPENGDGALLAITPPAVK-------RRRG------RPPKKNRSPADAG 2874
Query: 427 ELLSLVQNLDEKPRAGGAESGPEEDAL-----SLGAEACNFMQPVGARS-YKTLPHVTP- 479
+ + K + GA+ P + L L + QP+G + ++ P ++P
Sbjct: 2875 RGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPV 2934
Query: 480 ----KTPPPMAPKTPPPMT---------------PKTPPPVAPKPPSRGLLDGLVNGAAS 520
+ PP A P P T P P P+ P PP V +
Sbjct: 2935 EKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVT 2994
Query: 521 SAGIPEPPRLQGRG 534
+ I P + RG
Sbjct: 2995 TVTISTSPPKRKRG 3008
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 81.6 bits (200), Expect = 2e-15
Identities = 106/436 (24%), Positives = 141/436 (32%), Gaps = 83/436 (19%)
Query: 193 EGLQSPP-RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGL 251
+G SPP + Q PP+ P P P P P GG P P +P P
Sbjct: 48 QGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPPP 103
Query: 252 QGQRPTTTSVIFRPLAPKRANDSLGGLSP--APPPFLSSQGPTPLPSFTSGVPSHAPVSG 309
QG + + P + GG P PPP QGP P P P G
Sbjct: 104 QGDKSRSPR---SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ---GGNKPQGPPPPG 157
Query: 310 SPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSAR 369
P P G + SS P + P G +P PP P + +
Sbjct: 158 KPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ------GPPPQGGNK 211
Query: 370 PEAPAPGPGAPE-PPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPEL 428
P+ P P PG P+ PP + + + G Q +G + P P P+
Sbjct: 212 PQGPPP-PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ- 269
Query: 429 LSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK 488
N + P G GP G+++ + P G P+ PPP
Sbjct: 270 ---GGNKPQGPPPPGKPQGPPPQG---GSKSRSSRSPPG----------KPQGPPPQGGN 313
Query: 489 -----TPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQS 543
PPP P+ PPP G G P P + QG + +K +S
Sbjct: 314 QPQGPPPPPGKPQGPPP---------------QGGNKPQGPPPPGKPQGPPPQGGSKSRS 358
Query: 544 RADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAART 603
RSP P PP + + PPP N PQ +
Sbjct: 359 ------------------ARSPPGKPQGPPQQEGNNPQGPPPPAGGN-------PQQPQA 393
Query: 604 LPKAQSQGPRATPKQG 619
P Q QGP P+ G
Sbjct: 394 PPAGQPQGPPRPPQGG 409
Score = 65.1 bits (157), Expect = 2e-10
Identities = 104/428 (24%), Positives = 135/428 (31%), Gaps = 92/428 (21%)
Query: 295 PSFTSGVPSHAPVSGS------PSTP------------RSSGPVTATSSLYIPAPSRPVT 336
PS +G P AP G PS P + GP P P
Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88
Query: 337 PGGAPEPPAPPSAAAMTSTASIFLSAPLRPSA-------RPEAPAPGPGAPEPP----SA 385
P G P P P + S P +P +P+ P P PG P+ P
Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148
Query: 386 REQRISVPAARTGILQEARRRGTRKQMFRPGKEETK-----NSPNPELLSLVQNLDEKPR 440
+ Q P G + + +R PGK + N P + P+
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNK-SRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207
Query: 441 AGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK-----TPPPMTP 495
G GP G + ARS P P+ PPP PPP P
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARS----PPGKPQGPPPQGGNQPQGPPPPPGKP 263
Query: 496 KTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQG---RGGELFAKRQSRADRYVVEG 552
+ PPP G G P P + QG +GG R SR+ +G
Sbjct: 264 QGPPP---------------QGGNKPQGPPPPGKPQGPPPQGGS--KSRSSRSPPGKPQG 306
Query: 553 TPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGP 612
P G G +P+ P P P P + PPP N P P + QGP
Sbjct: 307 PPPQG-GNQPQGPPPPPGKP---------QGPPPQGGNKPQGP--------PPPGKPQGP 348
Query: 613 RATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQ 672
P QG R P + + P P P A G+P+ + + PA Q
Sbjct: 349 ---PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ-------APPAGQ 398
Query: 673 PTAEPLAP 680
P P P
Sbjct: 399 PQGPPRPP 406
Score = 37.7 bits (86), Expect = 0.040
Identities = 36/124 (29%), Positives = 47/124 (37%), Gaps = 12/124 (9%)
Query: 196 QSPP-RAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG- 253
+SPP + Q PP+ P P P P P GG P P +P P QG
Sbjct: 298 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPPPQGG 353
Query: 254 -QRPTTTSVIFRPLAP--KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS 310
+ + S +P P + N+ G P PP + Q P P+ P P G
Sbjct: 354 SKSRSARSPPGKPQGPPQQEGNNPQG---PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGR 410
Query: 311 PSTP 314
PS P
Sbjct: 411 PSRP 414
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 79.0 bits (193), Expect = 2e-14
Identities = 107/395 (27%), Positives = 131/395 (33%), Gaps = 103/395 (26%)
Query: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 271
PP P PAP +P GG+P P+P S P P L
Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPP----STAPPPPPLL------------------- 177
Query: 272 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAP 331
L P PPP S P P P + P H SPS P + L AP
Sbjct: 178 ------LEPPPPP---SMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAP 226
Query: 332 SRPVTPGGAPEPPAPP------------------SAAAMTSTASIFLSAPLRPSARPEAP 373
P P AP PA P A A ++P R A P+
Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286
Query: 374 APGPGAPEPPSAREQRISVP---AARTGIL--QEARRRGTRKQMFRPGKEETKNSPNPEL 428
A GP PEP + VP RT + QEA+ P KEE P
Sbjct: 287 ALGPN-PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQE--------APRKEEGATKKAPSR 337
Query: 429 LSLVQNLDEKPRAG-GAESGPEEDAL-SLGAEACNFMQPVGARSYKTLPHVTPK--TPPP 484
L L + +P + + PE D L A A P R ++ + TPPP
Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATA-----PASPRLGQSQSQADERAGTPPP 392
Query: 485 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 544
AP PPP P PPP P PP+ L A AG + P+
Sbjct: 393 -APPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK--------------- 435
Query: 545 ADRYVVEGTPGPGLGPRPRSPSP---TPSLPPSWK 576
+ P L P+P PSP S P W+
Sbjct: 436 --------SSSPALKPKPNPPSPENTASSAPVDWR 462
Score = 75.5 bits (184), Expect = 2e-13
Identities = 155/618 (25%), Positives = 211/618 (34%), Gaps = 130/618 (21%)
Query: 181 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 240
L + P L+ + +PP P A L P P P P +P P PA S
Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---------PAPA-SPH 243
Query: 241 NRSARPFTPG----------LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFL---- 286
R F PG L G++ T P +P S L P P P L
Sbjct: 244 TVGTRLFPPGGVTKWKSDVALNGRQAEATRA-SPPRSPAEPKGS--ALGPNPEPHLTFPR 300
Query: 287 SSQGPTPLPSFTSGVP----SHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPE 342
S + P P P TS +P AP +T ++ + S +I P+ V P APE
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQVYPDRAPE 359
Query: 343 PPAPPSAAAMTSTASIFLS-------------APLRPSARPEAPAPGPGAPEPPSAREQR 389
P P A T+ AS L P P P P P P P PP+A
Sbjct: 360 PDCPGELKA-TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--- 415
Query: 390 ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPE 449
+P A+ A T K P + N P+PE + +D + S E
Sbjct: 416 -PLPCAQKAAHPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAPVDWRD-----PSQME 468
Query: 450 EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP----PMAPK-----------TPPPMT 494
+ L A C + S++ P V P++ P P+ TPP +
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 495 PKT----------------------PPPVAPKPPSRGL---LDGLVNGAASSAGIPE--- 526
K+ P +P P R + L+ ++ AA P
Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
Query: 527 -PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPP 585
PP+ + GG + ++ AD + L P+ + PT SL P P I PP
Sbjct: 589 LPPKPRLEGGRIC---ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI--PP 643
Query: 586 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 645
P + P T PKA + GP ATP LK +
Sbjct: 644 KATPEPAIPPKATLWPATPPKA-TLGP-ATP----------------LKATSGPTTPLKA 685
Query: 646 TPGP----IASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELA 701
T GP A+ P T + S PA QP +P + V P A P T L
Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLP 744
Query: 702 SAPVPSPA--PPPEAPRG 717
+ S A PP +P G
Sbjct: 745 TQGARSSAAFPPKTSPGG 762
Score = 52.4 bits (124), Expect = 2e-06
Identities = 75/297 (25%), Positives = 103/297 (34%), Gaps = 53/297 (17%)
Query: 475 PHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGR 533
P +P PP PPP+ + PPP + PP +L+ L SS IP PP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPP----- 212
Query: 534 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLP-PSWKYSPNIRAPPP------ 586
++ P L P P P P P+ P P+ ++ R PP
Sbjct: 213 -------------DFIPPAPPLAFLAP-PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
Query: 587 ---IAYN---PLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 640
+A N + P + PK + GP P F P ++T+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPV 317
Query: 641 DEVPPTPGPIASGSPKTARVQ-------EIRRFSTPAPQPTAEPLAPTVL------APRA 687
E P G+ K A + IR S P EP P L +PR
Sbjct: 318 QEAQEAPRK-EEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 688 ATTLDEPIWR--TELASAPVPSPA---PPPEAPRGLGASPSSCGFQVARPRFSATRT 739
+ + R T + P+P PA PPP P A P C + A P T+T
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKT 433
Score = 41.6 bits (96), Expect = 0.003
Identities = 128/548 (23%), Positives = 174/548 (31%), Gaps = 136/548 (24%)
Query: 240 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 299
FN + T L+ + + F PL + N L +P+ P + + T S +
Sbjct: 58 FNTVSESGTATLKARPRVRPLLTFLPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVN 116
Query: 300 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 359
G + + S R P L IP P PG + PP + + S S
Sbjct: 117 G---NLRLYSSVGDLR---PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS-- 168
Query: 360 LSAPLRPSARPEAPAPGPGAPEPPSAREQRI----------------------------- 390
+AP P E P P AP PP E
Sbjct: 169 -TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227
Query: 391 --SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 448
VPA GTR +F PG S ++L E RA S
Sbjct: 228 PPPVPAPAPPAPASPHTVGTR--LFPPGGVTKWKSD----VALNGRQAEATRASPPRSPA 281
Query: 449 EEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPS 507
E +LG P+ P P + K PPP +T PV +
Sbjct: 282 EPKGSALG------------------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
Query: 508 RGLLDGLVNGAASSAGIPEPPRLQGR-GGELFAKRQSRAD---RYVVEGTPGPGLG---- 559
+G A S +P PP R +++ R D P LG
Sbjct: 324 PRKEEGATKKAPSR--LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381
Query: 560 ---PRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQS-----QG 611
R +P P P LPP P PPP +P P AA LP AQ G
Sbjct: 382 QADERAGTPPPAPPLPP-----PAPPLPPP-------APPLPPAAPPLPCAQKAAHPPAG 429
Query: 612 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSP----KTARVQEIR--- 664
TPK AL + +P PP+P AS +P ++++++R
Sbjct: 430 FTKTPKSSSPAL---KPKPN------------PPSPENTASSAPVDWRDPSQMEKLRNEL 474
Query: 665 -----------RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 713
RF + P PT +AP + L E + L S P PP
Sbjct: 475 AAYLCGSRREDRFLSHRPGPT---VAPQSKEGKKGPRLPE---KETLLSLPA-KDTPPGV 527
Query: 714 APRGLGAS 721
+ LG S
Sbjct: 528 PEKSLGGS 535
Score = 39.3 bits (90), Expect = 0.014
Identities = 101/446 (22%), Positives = 145/446 (32%), Gaps = 67/446 (15%)
Query: 197 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 256
S R + +P EA LP + A P PGGG P ++ Q
Sbjct: 729 SQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG---EVPCLYKPHCH------QSSLS 779
Query: 257 TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS 316
+V+ LA GG + P + P G+P+ P S P+
Sbjct: 780 REVAVVMPTLA-------RGGAAGPGEPVEVKEPP--------GLPAKPPASAQPTDELL 824
Query: 317 SGPVT-------ATSSLYIPAPSR---------PVTPGGAPEPPAPPSAAAMTSTASIFL 360
PVT + +L + A R + P S A S+ SIF
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 361 SA------PLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFR 414
S + P EA P E P+ R+ A T + R T+ +
Sbjct: 885 SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL--SRRHNWTKPEPQA 942
Query: 415 P-GKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEE----DALSLGAEACNFMQPVGAR 469
P E S P+ L ++ P EE + + E N +P
Sbjct: 943 PVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPA-- 1000
Query: 470 SYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPR 529
L ++ ++ PP + P P PP+ G A AG R
Sbjct: 1001 --PALQYLGRQSSPPRNNYSDLRQLPNAGPGA---PPALGF--SRFPAGARYAGAGGLER 1053
Query: 530 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS---PTPSLPPSWKYSPNIRAPPP 586
G G L KR + + G P G G SP+ P P P + + RAPP
Sbjct: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPG 1113
Query: 587 IAYNPLLSPFFPQAARTLPKAQSQGP 612
+ P LS AAR +A+ + P
Sbjct: 1114 GLHAPRLS--LEGAARGAAEAKHKAP 1137
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 79.0 bits (193), Expect = 2e-14
Identities = 107/395 (27%), Positives = 131/395 (33%), Gaps = 103/395 (26%)
Query: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 271
PP P PAP +P GG+P P+P S P P L
Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPP----STAPPPPPLL------------------- 177
Query: 272 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAP 331
L P PPP S P P P + P H SPS P + L AP
Sbjct: 178 ------LEPPPPP---SMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAP 226
Query: 332 SRPVTPGGAPEPPAPP------------------SAAAMTSTASIFLSAPLRPSARPEAP 373
P P AP PA P A A ++P R A P+
Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286
Query: 374 APGPGAPEPPSAREQRISVP---AARTGIL--QEARRRGTRKQMFRPGKEETKNSPNPEL 428
A GP PEP + VP RT + QEA+ P KEE P
Sbjct: 287 ALGPN-PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQE--------APRKEEGATKKAPSR 337
Query: 429 LSLVQNLDEKPRAG-GAESGPEEDAL-SLGAEACNFMQPVGARSYKTLPHVTPK--TPPP 484
L L + +P + + PE D L A A P R ++ + TPPP
Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATA-----PASPRLGQSQSQADERAGTPPP 392
Query: 485 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 544
AP PPP P PPP P PP+ L A AG + P+
Sbjct: 393 -APPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK--------------- 435
Query: 545 ADRYVVEGTPGPGLGPRPRSPSP---TPSLPPSWK 576
+ P L P+P PSP S P W+
Sbjct: 436 --------SSSPALKPKPNPPSPENTASSAPVDWR 462
Score = 75.5 bits (184), Expect = 2e-13
Identities = 155/618 (25%), Positives = 211/618 (34%), Gaps = 130/618 (21%)
Query: 181 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 240
L + P L+ + +PP P A L P P P P +P P PA S
Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---------PAPA-SPH 243
Query: 241 NRSARPFTPG----------LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFL---- 286
R F PG L G++ T P +P S L P P P L
Sbjct: 244 TVGTRLFPPGGVTKWKSDVALNGRQAEATRA-SPPRSPAEPKGS--ALGPNPEPHLTFPR 300
Query: 287 SSQGPTPLPSFTSGVP----SHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPE 342
S + P P P TS +P AP +T ++ + S +I P+ V P APE
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQVYPDRAPE 359
Query: 343 PPAPPSAAAMTSTASIFLS-------------APLRPSARPEAPAPGPGAPEPPSAREQR 389
P P A T+ AS L P P P P P P P PP+A
Sbjct: 360 PDCPGELKA-TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--- 415
Query: 390 ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPE 449
+P A+ A T K P + N P+PE + +D + S E
Sbjct: 416 -PLPCAQKAAHPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAPVDWRD-----PSQME 468
Query: 450 EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP----PMAPK-----------TPPPMT 494
+ L A C + S++ P V P++ P P+ TPP +
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 495 PKT----------------------PPPVAPKPPSRGL---LDGLVNGAASSAGIPE--- 526
K+ P +P P R + L+ ++ AA P
Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
Query: 527 -PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPP 585
PP+ + GG + ++ AD + L P+ + PT SL P P I PP
Sbjct: 589 LPPKPRLEGGRIC---ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI--PP 643
Query: 586 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 645
P + P T PKA + GP ATP LK +
Sbjct: 644 KATPEPAIPPKATLWPATPPKA-TLGP-ATP----------------LKATSGPTTPLKA 685
Query: 646 TPGP----IASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELA 701
T GP A+ P T + S PA QP +P + V P A P T L
Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLP 744
Query: 702 SAPVPSPA--PPPEAPRG 717
+ S A PP +P G
Sbjct: 745 TQGARSSAAFPPKTSPGG 762
Score = 52.4 bits (124), Expect = 2e-06
Identities = 75/297 (25%), Positives = 103/297 (34%), Gaps = 53/297 (17%)
Query: 475 PHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGR 533
P +P PP PPP+ + PPP + PP +L+ L SS IP PP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPP----- 212
Query: 534 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLP-PSWKYSPNIRAPPP------ 586
++ P L P P P P P+ P P+ ++ R PP
Sbjct: 213 -------------DFIPPAPPLAFLAP-PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
Query: 587 ---IAYN---PLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 640
+A N + P + PK + GP P F P ++T+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPV 317
Query: 641 DEVPPTPGPIASGSPKTARVQ-------EIRRFSTPAPQPTAEPLAPTVL------APRA 687
E P G+ K A + IR S P EP P L +PR
Sbjct: 318 QEAQEAPRK-EEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 688 ATTLDEPIWR--TELASAPVPSPA---PPPEAPRGLGASPSSCGFQVARPRFSATRT 739
+ + R T + P+P PA PPP P A P C + A P T+T
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKT 433
Score = 41.6 bits (96), Expect = 0.003
Identities = 128/548 (23%), Positives = 174/548 (31%), Gaps = 136/548 (24%)
Query: 240 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 299
FN + T L+ + + F PL + N L +P+ P + + T S +
Sbjct: 58 FNTVSESGTATLKARPRVRPLLTFLPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVN 116
Query: 300 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 359
G + + S R P L IP P PG + PP + + S S
Sbjct: 117 G---NLRLYSSVGDLR---PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS-- 168
Query: 360 LSAPLRPSARPEAPAPGPGAPEPPSAREQRI----------------------------- 390
+AP P E P P AP PP E
Sbjct: 169 -TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227
Query: 391 --SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 448
VPA GTR +F PG S ++L E RA S
Sbjct: 228 PPPVPAPAPPAPASPHTVGTR--LFPPGGVTKWKSD----VALNGRQAEATRASPPRSPA 281
Query: 449 EEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPS 507
E +LG P+ P P + K PPP +T PV +
Sbjct: 282 EPKGSALG------------------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
Query: 508 RGLLDGLVNGAASSAGIPEPPRLQGR-GGELFAKRQSRAD---RYVVEGTPGPGLG---- 559
+G A S +P PP R +++ R D P LG
Sbjct: 324 PRKEEGATKKAPSR--LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381
Query: 560 ---PRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQS-----QG 611
R +P P P LPP P PPP +P P AA LP AQ G
Sbjct: 382 QADERAGTPPPAPPLPP-----PAPPLPPP-------APPLPPAAPPLPCAQKAAHPPAG 429
Query: 612 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSP----KTARVQEIR--- 664
TPK AL + +P PP+P AS +P ++++++R
Sbjct: 430 FTKTPKSSSPAL---KPKPN------------PPSPENTASSAPVDWRDPSQMEKLRNEL 474
Query: 665 -----------RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 713
RF + P PT +AP + L E + L S P PP
Sbjct: 475 AAYLCGSRREDRFLSHRPGPT---VAPQSKEGKKGPRLPE---KETLLSLPA-KDTPPGV 527
Query: 714 APRGLGAS 721
+ LG S
Sbjct: 528 PEKSLGGS 535
Score = 39.3 bits (90), Expect = 0.014
Identities = 101/446 (22%), Positives = 145/446 (32%), Gaps = 67/446 (15%)
Query: 197 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 256
S R + +P EA LP + A P PGGG P ++ Q
Sbjct: 729 SQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG---EVPCLYKPHCH------QSSLS 779
Query: 257 TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS 316
+V+ LA GG + P + P G+P+ P S P+
Sbjct: 780 REVAVVMPTLA-------RGGAAGPGEPVEVKEPP--------GLPAKPPASAQPTDELL 824
Query: 317 SGPVT-------ATSSLYIPAPSR---------PVTPGGAPEPPAPPSAAAMTSTASIFL 360
PVT + +L + A R + P S A S+ SIF
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 361 SA------PLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFR 414
S + P EA P E P+ R+ A T + R T+ +
Sbjct: 885 SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL--SRRHNWTKPEPQA 942
Query: 415 P-GKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEE----DALSLGAEACNFMQPVGAR 469
P E S P+ L ++ P EE + + E N +P
Sbjct: 943 PVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPA-- 1000
Query: 470 SYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPR 529
L ++ ++ PP + P P PP+ G A AG R
Sbjct: 1001 --PALQYLGRQSSPPRNNYSDLRQLPNAGPGA---PPALGF--SRFPAGARYAGAGGLER 1053
Query: 530 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS---PTPSLPPSWKYSPNIRAPPP 586
G G L KR + + G P G G SP+ P P P + + RAPP
Sbjct: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPG 1113
Query: 587 IAYNPLLSPFFPQAARTLPKAQSQGP 612
+ P LS AAR +A+ + P
Sbjct: 1114 GLHAPRLS--LEGAARGAAEAKHKAP 1137
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 79.0 bits (193), Expect = 2e-14
Identities = 107/395 (27%), Positives = 131/395 (33%), Gaps = 103/395 (26%)
Query: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 271
PP P PAP +P GG+P P+P S P P L
Sbjct: 141 PPPPGPAPGPPQDISEPPGGSPLPSPP----STAPPPPPLL------------------- 177
Query: 272 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAP 331
L P PPP S P P P + P H SPS P + L AP
Sbjct: 178 ------LEPPPPP---SMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAP 226
Query: 332 SRPVTPGGAPEPPAPP------------------SAAAMTSTASIFLSAPLRPSARPEAP 373
P P AP PA P A A ++P R A P+
Sbjct: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286
Query: 374 APGPGAPEPPSAREQRISVP---AARTGIL--QEARRRGTRKQMFRPGKEETKNSPNPEL 428
A GP PEP + VP RT + QEA+ P KEE P
Sbjct: 287 ALGPN-PEPHLTFPRSFKVPPPTPVRTSSIPVQEAQE--------APRKEEGATKKAPSR 337
Query: 429 LSLVQNLDEKPRAG-GAESGPEEDAL-SLGAEACNFMQPVGARSYKTLPHVTPK--TPPP 484
L L + +P + + PE D L A A P R ++ + TPPP
Sbjct: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATA-----PASPRLGQSQSQADERAGTPPP 392
Query: 485 MAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSR 544
AP PPP P PPP P PP+ L A AG + P+
Sbjct: 393 -APPLPPP-APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK--------------- 435
Query: 545 ADRYVVEGTPGPGLGPRPRSPSP---TPSLPPSWK 576
+ P L P+P PSP S P W+
Sbjct: 436 --------SSSPALKPKPNPPSPENTASSAPVDWR 462
Score = 75.5 bits (184), Expect = 2e-13
Identities = 155/618 (25%), Positives = 211/618 (34%), Gaps = 130/618 (21%)
Query: 181 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIF 240
L + P L+ + +PP P A L P P P P +P P PA S
Sbjct: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---------PAPA-SPH 243
Query: 241 NRSARPFTPG----------LQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFL---- 286
R F PG L G++ T P +P S L P P P L
Sbjct: 244 TVGTRLFPPGGVTKWKSDVALNGRQAEATRA-SPPRSPAEPKGS--ALGPNPEPHLTFPR 300
Query: 287 SSQGPTPLPSFTSGVP----SHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPE 342
S + P P P TS +P AP +T ++ + S +I P+ V P APE
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RPASQVYPDRAPE 359
Query: 343 PPAPPSAAAMTSTASIFLS-------------APLRPSARPEAPAPGPGAPEPPSAREQR 389
P P A T+ AS L P P P P P P P PP+A
Sbjct: 360 PDCPGELKA-TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--- 415
Query: 390 ISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPE 449
+P A+ A T K P + N P+PE + +D + S E
Sbjct: 416 -PLPCAQKAAHPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAPVDWRD-----PSQME 468
Query: 450 EDALSLGAEACNFMQPVGARSYKTLPHVTPKTPP----PMAPK-----------TPPPMT 494
+ L A C + S++ P V P++ P P+ TPP +
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 495 PKT----------------------PPPVAPKPPSRGL---LDGLVNGAASSAGIPE--- 526
K+ P +P P R + L+ ++ AA P
Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
Query: 527 -PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPP 585
PP+ + GG + ++ AD + L P+ + PT SL P P I PP
Sbjct: 589 LPPKPRLEGGRIC---ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI--PP 643
Query: 586 PIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 645
P + P T PKA + GP ATP LK +
Sbjct: 644 KATPEPAIPPKATLWPATPPKA-TLGP-ATP----------------LKATSGPTTPLKA 685
Query: 646 TPGP----IASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELA 701
T GP A+ P T + S PA QP +P + V P A P T L
Sbjct: 686 TSGPAIASTATTLPTTTSQLMAEKDSGPAGQP-EKPASQEVSTPSQARGEGSPSEATRLP 744
Query: 702 SAPVPSPA--PPPEAPRG 717
+ S A PP +P G
Sbjct: 745 TQGARSSAAFPPKTSPGG 762
Score = 52.4 bits (124), Expect = 2e-06
Identities = 75/297 (25%), Positives = 103/297 (34%), Gaps = 53/297 (17%)
Query: 475 PHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGL-VNGAASSAGIPEPPRLQGR 533
P +P PP PPP+ + PPP + PP +L+ L SS IP PP
Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPP----- 212
Query: 534 GGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLP-PSWKYSPNIRAPPP------ 586
++ P L P P P P P+ P P+ ++ R PP
Sbjct: 213 -------------DFIPPAPPLAFLAP-PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
Query: 587 ---IAYN---PLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 640
+A N + P + PK + GP P F P ++T+
Sbjct: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPV 317
Query: 641 DEVPPTPGPIASGSPKTARVQ-------EIRRFSTPAPQPTAEPLAPTVL------APRA 687
E P G+ K A + IR S P EP P L +PR
Sbjct: 318 QEAQEAPRK-EEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRL 376
Query: 688 ATTLDEPIWR--TELASAPVPSPA---PPPEAPRGLGASPSSCGFQVARPRFSATRT 739
+ + R T + P+P PA PPP P A P C + A P T+T
Sbjct: 377 GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKT 433
Score = 41.6 bits (96), Expect = 0.003
Identities = 128/548 (23%), Positives = 174/548 (31%), Gaps = 136/548 (24%)
Query: 240 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 299
FN + T L+ + + F PL + N L +P+ P + + T S +
Sbjct: 58 FNTVSESGTATLKARPRVRPLLTFLPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVN 116
Query: 300 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 359
G + + S R P L IP P PG + PP + + S S
Sbjct: 117 G---NLRLYSSVGDLR---PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPS-- 168
Query: 360 LSAPLRPSARPEAPAPGPGAPEPPSAREQRI----------------------------- 390
+AP P E P P AP PP E
Sbjct: 169 -TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227
Query: 391 --SVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 448
VPA GTR +F PG S ++L E RA S
Sbjct: 228 PPPVPAPAPPAPASPHTVGTR--LFPPGGVTKWKSD----VALNGRQAEATRASPPRSPA 281
Query: 449 EEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPS 507
E +LG P+ P P + K PPP +T PV +
Sbjct: 282 EPKGSALG------------------PNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
Query: 508 RGLLDGLVNGAASSAGIPEPPRLQGR-GGELFAKRQSRAD---RYVVEGTPGPGLG---- 559
+G A S +P PP R +++ R D P LG
Sbjct: 324 PRKEEGATKKAPSR--LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS 381
Query: 560 ---PRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQS-----QG 611
R +P P P LPP P PPP +P P AA LP AQ G
Sbjct: 382 QADERAGTPPPAPPLPP-----PAPPLPPP-------APPLPPAAPPLPCAQKAAHPPAG 429
Query: 612 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSP----KTARVQEIR--- 664
TPK AL + +P PP+P AS +P ++++++R
Sbjct: 430 FTKTPKSSSPAL---KPKPN------------PPSPENTASSAPVDWRDPSQMEKLRNEL 474
Query: 665 -----------RFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 713
RF + P PT +AP + L E + L S P PP
Sbjct: 475 AAYLCGSRREDRFLSHRPGPT---VAPQSKEGKKGPRLPE---KETLLSLPA-KDTPPGV 527
Query: 714 APRGLGAS 721
+ LG S
Sbjct: 528 PEKSLGGS 535
Score = 39.3 bits (90), Expect = 0.014
Identities = 101/446 (22%), Positives = 145/446 (32%), Gaps = 67/446 (15%)
Query: 197 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 256
S R + +P EA LP + A P PGGG P ++ Q
Sbjct: 729 SQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGG---EVPCLYKPHCH------QSSLS 779
Query: 257 TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRS 316
+V+ LA GG + P + P G+P+ P S P+
Sbjct: 780 REVAVVMPTLA-------RGGAAGPGEPVEVKEPP--------GLPAKPPASAQPTDELL 824
Query: 317 SGPVT-------ATSSLYIPAPSR---------PVTPGGAPEPPAPPSAAAMTSTASIFL 360
PVT + +L + A R + P S A S+ SIF
Sbjct: 825 RHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFH 884
Query: 361 SA------PLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFR 414
S + P EA P E P+ R+ A T + R T+ +
Sbjct: 885 SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL--SRRHNWTKPEPQA 942
Query: 415 P-GKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEE----DALSLGAEACNFMQPVGAR 469
P E S P+ L ++ P EE + + E N +P
Sbjct: 943 PVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPA-- 1000
Query: 470 SYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPR 529
L ++ ++ PP + P P PP+ G A AG R
Sbjct: 1001 --PALQYLGRQSSPPRNNYSDLRQLPNAGPGA---PPALGF--SRFPAGARYAGAGGLER 1053
Query: 530 LQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS---PTPSLPPSWKYSPNIRAPPP 586
G G L KR + + G P G G SP+ P P P + + RAPP
Sbjct: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPG 1113
Query: 587 IAYNPLLSPFFPQAARTLPKAQSQGP 612
+ P LS AAR +A+ + P
Sbjct: 1114 GLHAPRLS--LEGAARGAAEAKHKAP 1137
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 78.2 bits (191), Expect = 3e-14
Identities = 181/721 (25%), Positives = 232/721 (32%), Gaps = 158/721 (21%)
Query: 74 FKKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAFSDARSLTNQSDWDSPYL 133
F RQR + L +FGA G G E G P + A S AR L P
Sbjct: 534 FLTPRQRNLQRALSAFGAHRGLGFGPEFGRP------VPRPATSLARFLKKTLSEKKPIA 587
Query: 134 DM---ELARAGSRASEGQ-----GSGLGGQLSEVSGRGVQLFEQQ---RQRADSSTQELA 182
+ + ARAG A G L G E G + L Q R D+
Sbjct: 588 RLRGSQKARAGGPAVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAP 647
Query: 183 RVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPL-PAPVASPRPFQPGGGAPTPAPSIFN 241
+ P + + L SPP PP + P PL PA PRP P G
Sbjct: 648 QPAPRTLSHWSALLSPP-VPPRPPSSGPPPAPPLSPALSGLPRPASPYG----------- 695
Query: 242 RSARPFTPGLQGQRPTTTSVIFRPLAPKR---ANDSLGGLSPAPPPFLSSQGPTPLPSFT 298
L+ P + P AP+ A +SP PP L + P P PSF
Sbjct: 696 --------SLRRHPPPWAAPAHVPPAPQASWWAFVEPPAVSPEVPPDLLA-FPGPRPSFR 746
Query: 299 SGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPG-GAPEPPAPPSAAAMTSTAS 357
A ++PR+S A S L P PS +PG G P APPS T
Sbjct: 747 GSRRRGAAFGFPGASPRASRR-RAWSPLASPQPSLRSSPGLGYCSPLAPPSPQLSLRTGP 805
Query: 358 I---FLSAPLRPSARPEAPAP--------GPGAPEPPSAREQRISVPAARTGILQEARRR 406
FL RP + E+PAP PG+P P S R P+ G+ RR
Sbjct: 806 FQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRP-----PSPPLGLCHSPRRS 860
Query: 407 GTRKQMFRPGKEETKNSPNPELLSLVQNLD-EKPRAGGAESGPEEDALSLGAEACNFMQP 465
P + P + L +P GA P E S +P
Sbjct: 861 SLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLEHRESP-------REP 913
Query: 466 VGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIP 525
+ TP T PP+AP M P PP +P P G G + +P
Sbjct: 914 EDSE--------TPWTVPPLAPSWDVDMPPTQRPP-SPWPGGAGSR----RGFSRPPPVP 960
Query: 526 EPPRLQGRG---GELFAKRQSRADRYVV----EGTPGPG-----LGPRPRSPS------- 566
E P LQ G AD V PGPG GP P P
Sbjct: 961 ENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGD 1020
Query: 567 ---------PTPS-----LPPSWKYSPNIRAPPPIAYNPLLSPFFPQAA----------- 601
PTP+ PP P P P LS +P AA
Sbjct: 1021 PQLPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLS--YPLAACDQTRATWPPW 1078
Query: 602 ---RTLPKAQS-----QGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG 653
TLP+A + + P PK G + PG A
Sbjct: 1079 HRWGTLPQAAAPLAPIRAPEPLPKGG---------------------ERRQAAPGRFAVV 1117
Query: 654 SPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 713
P+ ++ +R +P +P+ PRA + +W A P P P+
Sbjct: 1118 MPRVQKLSSFQRVGPATLKPQVQPIQDP--KPRACSLRWSCLWLRADAYGPWPRVHTHPQ 1175
Query: 714 A 714
+
Sbjct: 1176 S 1176
Score = 60.5 bits (145), Expect = 6e-09
Identities = 147/615 (23%), Positives = 203/615 (33%), Gaps = 158/615 (25%)
Query: 226 FQPGGGAPTPAPSI----FNRSA----RPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 277
F P G P P P+ F + +P Q+ R A KR L G
Sbjct: 557 FGPEFGRPVPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGPAVREAAYKRFGYKLAG 616
Query: 278 LSPAPP--PFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPV 335
+ P P P + + P S + P + P+ PR+ +A S P P RP
Sbjct: 617 MDPEKPGTPIVLRRAQ---PRARSSNDARRPPAPQPA-PRTLSHWSALLSP--PVPPRPP 670
Query: 336 TPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAP--------EPPSARE 387
+ G P PP P+ + + AS + S P APA P AP EPP+
Sbjct: 671 SSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPW-AAPAHVPPAPQASWWAFVEPPAVSP 729
Query: 388 Q----RISVPAARTGILQEARR-----------RGTRKQMFRPGKEETKNSPNPELLSLV 432
+ ++ P R RR R +R++ + P SP P L S
Sbjct: 730 EVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSP-----LASPQPSLRS-- 782
Query: 433 QNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGAR-SYKTLPHVTPKTPPPMAPK--- 488
S G C+ + P + S +T P P PP P+
Sbjct: 783 ---------------------SPGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQ 821
Query: 489 -TPPPM-------TPKTPPPVAPKPPSRGLLDGLVNG-AASSAGIP-----------EPP 528
+P P P +P P +P+PPS L GL + SS +P EPP
Sbjct: 822 ESPAPRRAAGRLGPPGSPLPGSPRPPSPPL--GLCHSPRRSSLNLPSRLPHTWRRLSEPP 879
Query: 529 ------------RLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPS------PTPS 570
R G A + R E + P P P +PS PT
Sbjct: 880 TRAVKPQVRLPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVP-PLAPSWDVDMPPTQR 938
Query: 571 LPPSWKYSPNIR----APPPIAYNPLLSPFFPQAARTLPKAQSQGPRAT----------- 615
P W R PPP+ NP L P + TL Q + P A
Sbjct: 939 PPSPWPGGAGSRRGFSRPPPVPENPFLQLLGPVPSPTL---QPEDPAADMTRVFLGRHHE 995
Query: 616 --PKQGIKALDFMRHQPYQ---LKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPA 670
P Q K+ +P + L + PPTP P +P + TP
Sbjct: 996 PGPGQLTKSAGPTPEKPEEEATLGDPQLPAETKPPTPAPPKDVTPP--------KDITPP 1047
Query: 671 PQ--PTAEPLAPTVLAPRAATTLDEPIW----------RTELASAPVPSPAPPPEAPRGL 718
P + L P++ P AA W + AP+ +P P P+
Sbjct: 1048 KDVLPEQKTLRPSLSYPLAACDQTRATWPPWHRWGTLPQAAAPLAPIRAPEPLPKGGERR 1107
Query: 719 GASPSSCGFQVARPR 733
A+P F V PR
Sbjct: 1108 QAAPGR--FAVVMPR 1120
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/183 (22%), Positives = 62/183 (33%), Gaps = 30/183 (16%)
Query: 340 APEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGI 399
A +PPAP + T LR + +P APAP AP P P A +
Sbjct: 2490 AEKPPAPEAQPTSVGTGPPAKPVLLRATPKPLAPAPLAKAPRLPIK-------PVAAPVL 2542
Query: 400 LQEARRRGTRKQMFRPGKEETKNS-----PNPELLSLVQNLDEKPRAGGAES-------- 446
Q+ T + T NS P ++ ++V+ + R G E+
Sbjct: 2543 AQDQASPETTSPSPELVRYSTLNSEHFPQPTQQIKNIVRQYQQPFRGGRPEALRKDGGKV 2602
Query: 447 -----GPEEDALSLGAEACNFM-----QPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPK 496
P E+AL + + V + + VT P MAP + P
Sbjct: 2603 FMKRPDPHEEALMILKGQMTHLAAAPGTQVSREAVALVKPVTSAPRPSMAPTSALPSRSL 2662
Query: 497 TPP 499
PP
Sbjct: 2663 EPP 2665
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 78.2 bits (191), Expect = 3e-14
Identities = 138/585 (23%), Positives = 196/585 (33%), Gaps = 157/585 (26%)
Query: 154 GQLSEVSGRGVQLFEQQRQRADSSTQEL---ARVEPAAMLNGEGLQSPPRAQSAPPEAAV 210
G+ S VS Q R R SS+ + ++ + +G L S ++ P E++
Sbjct: 394 GRFSSVSS------PQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQP-ESST 446
Query: 211 LPPSPLPAPVASPRPFQPGGGAPTPAPSIFN-RSARPFTPGLQGQRPTTTSVIFRPLAPK 269
S +P P P GG+ A + RS+ G R + + RP P
Sbjct: 447 ASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSS-----GQLSGRSVSLRKLKRPPPPP 501
Query: 270 RANDSL---------GGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPV 320
R SL G L P P Q P P T G A + P P +S
Sbjct: 502 RRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEG-AGAAPCPPNPANS--- 557
Query: 321 TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTA-SIFLSAPLRPSARPEAPAPGPGA 379
++P ++PGG+ PP P S+ S P P P PG
Sbjct: 558 ------WVPG----LSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGK 607
Query: 380 PEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNL--DE 437
+PP +P + + SP + S + +L
Sbjct: 608 AQPP------------------------------KPERVTSLRSPGASVSSSLTSLCSSS 637
Query: 438 KPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKT 497
A SGP+ + P+G R + PH PK P AP +PPP P++
Sbjct: 638 SDPAPSDRSGPQ------------ILTPLGDR-FVIPPH--PKVP---APFSPPPSKPRS 679
Query: 498 PPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 557
P P AP + ++ G V + + A PP TP
Sbjct: 680 PNPAAPALAAPAVVPGPV--STTDASPQSPP------------------------TPQTT 713
Query: 558 LGPRPRSP------SPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQG 611
L P SP SP PS PPS Y P PPP P + P A+ T + Q
Sbjct: 714 LTPLQESPVISKDQSPPPSPPPS--YHP----PPPPTKKPEVVVEAPSASET-AEEPLQD 766
Query: 612 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG-SPKTARVQEIRRFSTPA 670
P P PP P P S E FS +
Sbjct: 767 PNWPP---------------------------PPPPAPEEQDLSMADFPPPEEAFFSVAS 799
Query: 671 PQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAP 715
P+P +P +++ AA++ + + +P P PAPP AP
Sbjct: 800 PEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844
Score = 72.4 bits (176), Expect = 1e-12
Identities = 104/440 (23%), Positives = 148/440 (33%), Gaps = 55/440 (12%)
Query: 205 PPEAAVLPP-SPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIF 263
PP V P SP P+ SP P P AP P + T Q P T
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVS------TTDASPQSPPTPQTTL 714
Query: 264 RPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGS--------PSTPR 315
PL P+PPP S P P P+ V AP + P+ P
Sbjct: 715 TPLQESPVISKDQSPPPSPPP---SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPP 771
Query: 316 SSGPVTATSSLYI---PAPSR---------PVTPGGAPEPPAPPSAAAMTSTASIFLSAP 363
P L + P P P P G+PE + P+A++ ++TA
Sbjct: 772 PPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATA-----LQ 826
Query: 364 LRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNS 423
++P P+ P P P AP P S+ ++ L + G K P ++
Sbjct: 827 IQPPGSPDPP-PAPPAPAPASSAPGHVAK-------LPQKEPVGCSKGGGPPREDVGAPL 878
Query: 424 PNPELLSLVQNLDEKPRAGGAES---GPEEDALSLGAEACNFMQPVGARSYKTLPHVTPK 480
P LL +V+ L GGA + GP L PV A S V K
Sbjct: 879 VTPSLLQMVR-LRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLK 937
Query: 481 TPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAK 540
A + P PP P+PP + +S + R + +
Sbjct: 938 ACSLAASEGLSSAQPNGPPEAEPRPPQSP-------ASTASFIFSKGSRKLQLERPVSPE 990
Query: 541 RQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYN-PLLSPFFPQ 599
Q+ R +V P++P +P PP P++ PPP + + P P
Sbjct: 991 TQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAP 1050
Query: 600 AARTLPKAQSQGPRATPKQG 619
LP Q + R + G
Sbjct: 1051 PTNGLPHTQDRTKRELAENG 1070
Score = 60.5 bits (145), Expect = 6e-09
Identities = 92/364 (25%), Positives = 124/364 (34%), Gaps = 93/364 (25%)
Query: 196 QSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQR 255
QSPP Q+ L SP+ + SP P P P P P+ ++
Sbjct: 705 QSPPTPQTT---LTPLQESPVISKDQSPPPSPPPSYHPPPPPT---------------KK 746
Query: 256 PTTTSVIFRPLAPKRANDSLGGLS--PAPPPFLSSQG------PTPLPSFTSGVPSHAPV 307
P V+ P A + A + L + P PPP Q P P +F S V S P
Sbjct: 747 PEV--VVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS-VASPEPA 803
Query: 308 SGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTA----------- 356
S S S P ++SS A + + P G+P+PP P A A S+A
Sbjct: 804 GPSGSPELVSSPAASSSS----ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKE 859
Query: 357 ----------------------SIFLSAPLRPSARP---EAPAPGPGAPEPPSARE---Q 388
S+ LR P PA GP AP+ P R +
Sbjct: 860 PVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGR 919
Query: 389 RISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGP 448
VPA +G+ R + N P PE +PR + +
Sbjct: 920 ASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGP-PEA---------EPRPPQSPAST 969
Query: 449 EEDALSLGAEACNFMQPVGARSYKTLPH-------VTPKTPPPMAPKTPPPMTPKTPPPV 501
S G+ +PV + L + PP APK +PK PPPV
Sbjct: 970 ASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK----SPKAPPPV 1025
Query: 502 APKP 505
A KP
Sbjct: 1026 ARKP 1029
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 76.6 bits (187), Expect = 8e-14
Identities = 99/444 (22%), Positives = 136/444 (30%), Gaps = 81/444 (18%)
Query: 279 SPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPG 338
+P+PP + P+P P+ T+ +P S P+T ++ P T T PS P+T
Sbjct: 1398 TPSPP----TTTPSPPPTSTTTLPPTTTPS-PPTTTTTTPPPTTT-------PSPPITTT 1445
Query: 339 GAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTG 398
P P PS T+T + P P+ P P P P + + P+ T
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPT- 1504
Query: 399 ILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAE 458
T +P +L P + P S
Sbjct: 1505 --------------------TTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544
Query: 459 ACNFMQPVGA-RSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPKPPSRGLLDGLVN 516
P+ S TLP T +PPP TPPP T +PP P PP+ +
Sbjct: 1545 T-----PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT------ITT 1593
Query: 517 GAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWK 576
P PP TP P P P P+ TP PP
Sbjct: 1594 TTPPPTTTPSPPT-------------------TTTTTPPPTTTPSP--PTTTPITPP--- 1629
Query: 577 YSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTA 636
+ PP +P P T P + P T P ++
Sbjct: 1630 -TSTTTLPPTTTPSPP-----PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683
Query: 637 MFCFDEVPP-----TPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTL 691
PP TP P + S +TP+P PT P TT
Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743
Query: 692 DEPIWRTELASAPVPSPAPPPEAP 715
+ T +S +P PP P
Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITP 1767
Score = 72.4 bits (176), Expect = 1e-12
Identities = 80/315 (25%), Positives = 108/315 (34%), Gaps = 27/315 (8%)
Query: 198 PPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPT 257
PP +PP + P P P SP P TP+P + P P PT
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTP--SPPTTTPSPPTTTPSPPTTTTTTPP--PTTTPSPPT 1504
Query: 258 TTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSS 317
TT P+ P + +L + PP ++ TP P+ T P+ P+ +P T ++
Sbjct: 1505 TT-----PITPPASTTTLPPTTTPSPPTTTT--TTPPPTTTPSPPTTTPI--TPPTSTTT 1555
Query: 318 GPVTATSSLYIPAPSRPVTPGGAPEPPAP----PSAAAMTSTASIFLSAPLRPSARPEAP 373
P T T S P P+ TP P P PS +T+T + P P+ P
Sbjct: 1556 LPPTTTPS---PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP 1612
Query: 374 APGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ 433
P P PP+ I+ P + T + P T + P S
Sbjct: 1613 PP-TTTPSPPTTTP--ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPI 1669
Query: 434 NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPM 493
P S P S P S P T TP +PPP
Sbjct: 1670 TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS---SPITTTTTPSSTTTPSPPPT 1726
Query: 494 TPKTP-PPVAPKPPS 507
T TP P P PP+
Sbjct: 1727 TMTTPSPTTTPSPPT 1741
Score = 70.9 bits (172), Expect = 4e-12
Identities = 115/501 (22%), Positives = 146/501 (29%), Gaps = 116/501 (23%)
Query: 215 PLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDS 274
P+ + +P P PT PS S P PTTT+ P
Sbjct: 1391 PMDKCITTPSP-------PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT------- 1436
Query: 275 LGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRP 334
+P+PP ++ TP P+ T P + P+T S P T T S PS P
Sbjct: 1437 ----TPSPPITTTT---TPPPTTTPSPPISTTTTPPPTTTPS--PPTTTPSPPTTTPSPP 1487
Query: 335 VTPGGAPEP---PAPPSAAAMTSTASIFLSAPLRPSARPEAPA------PGPGAPEPPSA 385
T P P P+PP+ +T AS + L P+ P P P P PP+
Sbjct: 1488 TTTTTTPPPTTTPSPPTTTPITPPAS---TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544
Query: 386 REQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAE 445
I+ P + T + P T + P S P
Sbjct: 1545 TP--ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602
Query: 446 SGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKP 505
S P + T P T +PP P TPP T PP P P
Sbjct: 1603 SPP-------------------TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1643
Query: 506 PSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSP 565
P ++ P P TP P P P
Sbjct: 1644 P------------PTTTTTPPPTT-----------------------TPSPPTTTTPSPP 1668
Query: 566 SPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDF 625
T + PP P PI P SP P T P P TP
Sbjct: 1669 ITTTTTPP-----PTTTPSSPITTTP--SP--PTTTMTTP-----SPTTTPS-------- 1706
Query: 626 MRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAP 685
P T P P + + SP T +T P T+ PL T L P
Sbjct: 1707 ---SPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP 1763
Query: 686 RAATTLDEPIWRTELASAPVP 706
P T + VP
Sbjct: 1764 SITPPTFSPFSTTTPTTPCVP 1784
Score = 66.6 bits (161), Expect = 8e-11
Identities = 96/410 (23%), Positives = 127/410 (30%), Gaps = 62/410 (15%)
Query: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRA 271
PP+ P+P + P P+P + TP TT P P
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIST 1460
Query: 272 NDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIP-- 329
+ + PP + PT PS + + P + +PS P ++ S+ +P
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPT 1520
Query: 330 -APSRPVTPGGAPEP---PAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSA 385
PS P T P P P+PP+ +T S + L P+ P P P P +
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS---TTTLPPTTTPSPPPTTTTTPPPTTT 1577
Query: 386 REQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAE 445
S P T P T P S P
Sbjct: 1578 P----SPPTTTTP---------------SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP 1618
Query: 446 SGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPP-PVAPK 504
S P ++ S TLP T +PPP TPPP T +PP P
Sbjct: 1619 SPPTTTPIT------------PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666
Query: 505 PPSRGLLDGLVNGAASS--AGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRP 562
PP SS P PP + + + TP P P
Sbjct: 1667 PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP---SPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 563 -------RSPSPTPS--------LPPSWKYSPNIRAP-PPIAYNPLLSPF 596
SP+ TPS LPP+ SP P PP P SPF
Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPF 1773
Score = 63.9 bits (154), Expect = 5e-10
Identities = 117/571 (20%), Positives = 178/571 (31%), Gaps = 70/571 (12%)
Query: 212 PPSPLP---APVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP 268
PP+ P +P P G PT P + P Q PTTT +
Sbjct: 1895 PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI------- 1947
Query: 269 KRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYI 328
+ ++P P P +Q PT P T+ + P TP ++ P+T T+++
Sbjct: 1948 ----TTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-T 2000
Query: 329 PAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEP 382
P P TP G P P T T + + P+ P P P P +
Sbjct: 2001 PTP----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2056
Query: 383 PSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLV 432
P+ + T + GT+ P T +P P ++
Sbjct: 2057 PTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2111
Query: 433 QNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAP 487
+ P G ++ P ++ P G ++ T P VTP TP P
Sbjct: 2112 TTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGT 2169
Query: 488 KTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSR 544
+TP T V P P G ++ + P P Q +
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2229
Query: 545 ADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAART 603
GT P P + + TP+ P+ +P P +P Q T
Sbjct: 2230 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289
Query: 604 LPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEI 663
P + TP T + V PTP P + +P T +
Sbjct: 2290 TPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2341
Query: 664 RRFS-TPAP----QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRG 717
+ TP P PT P+ T + P T + T + + +P P P +
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2401
Query: 718 LGASPSSCGFQVARPRFSATRTGLQAHVWRP 748
+P + V + T TG Q P
Sbjct: 2402 PTTTPITTTTTVTP---TPTPTGTQTPTTTP 2429
Score = 63.5 bits (153), Expect = 7e-10
Identities = 78/321 (24%), Positives = 107/321 (33%), Gaps = 51/321 (15%)
Query: 197 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 256
SPP + P P P P+ P TP+P + P P P
Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP--PTTTPSPP 1542
Query: 257 TTTSVIFRPLAPKRANDSL-GGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPR 315
TTT P+ P + +L +P+PPP ++ TP P+ T PS P + +PS P
Sbjct: 1543 TTT-----PITPPTSTTTLPPTTTPSPPPTTTT---TPPPTTT---PS-PPTTTTPSPP- 1589
Query: 316 SSGPVTATSSLYIPAPSRPVTPGGAPEP---PAPPSAAAMTSTASIFLSAPLRPSARPEA 372
+T T+ PS P T P P P+PP+ +T S + L P+ P
Sbjct: 1590 ---TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS---TTTLPPTTTPSP 1643
Query: 373 P------APGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNP 426
P P P PP+ + T P T +SP
Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTTPSPPITTTTT-----------------PPPTTTPSSPIT 1686
Query: 427 ELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMA 486
S P S P + + P + T T +PP
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPT---TMTTPSPTTTPSPPTTT 1743
Query: 487 PKTPPPMTPKTPPPVAPKPPS 507
T PP T +P P PPS
Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPS 1764
Score = 62.0 bits (149), Expect = 2e-09
Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%)
Query: 222 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 281
+P P G PT P + P Q PTTT + + ++P
Sbjct: 2299 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 2347
Query: 282 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 341
P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G
Sbjct: 2348 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 2400
Query: 342 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 395
P P T T + + P+ P P P P + P+ +
Sbjct: 2401 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 2455
Query: 396 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 445
T + GT+ P T +P P ++ + P G +
Sbjct: 2456 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2515
Query: 446 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 500
+ P ++ P G ++ T P VTP TP P +TP T
Sbjct: 2516 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 2573
Query: 501 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 557
V P P G ++ + P P Q + GT P
Sbjct: 2574 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2633
Query: 558 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 616
P + + TP+ P+ +P P +P Q T P + TP
Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2693
Query: 617 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 671
T + V PTP P + +P T + + TP P
Sbjct: 2694 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2745
Query: 672 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 730
PT P+ T + P T + T + + +P P P + +P + V
Sbjct: 2746 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2805
Query: 731 RPRFSATRTGLQAHVWRP 748
+ T TG Q P
Sbjct: 2806 P---TPTPTGTQTPTTTP 2820
Score = 62.0 bits (149), Expect = 2e-09
Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%)
Query: 222 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 281
+P P G PT P + P Q PTTT + + ++P
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 2784
Query: 282 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 341
P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G
Sbjct: 2785 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 2837
Query: 342 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 395
P P T T + + P+ P P P P + P+ +
Sbjct: 2838 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 2892
Query: 396 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 445
T + GT+ P T +P P ++ + P G +
Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2952
Query: 446 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 500
+ P ++ P G ++ T P VTP TP P +TP T
Sbjct: 2953 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 3010
Query: 501 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 557
V P P G ++ + P P Q + GT P
Sbjct: 3011 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3070
Query: 558 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 616
P + + TP+ P+ +P P +P Q T P + TP
Sbjct: 3071 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130
Query: 617 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 671
T + V PTP P + +P T + + TP P
Sbjct: 3131 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3182
Query: 672 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 730
PT P+ T + P T + T + + +P P P + +P + V
Sbjct: 3183 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3242
Query: 731 RPRFSATRTGLQAHVWRP 748
+ T TG Q P
Sbjct: 3243 P---TPTPTGTQTPTTTP 3257
Score = 62.0 bits (149), Expect = 2e-09
Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%)
Query: 222 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 281
+P P G PT P + P Q PTTT + + ++P
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 3221
Query: 282 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 341
P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G
Sbjct: 3222 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 3274
Query: 342 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 395
P P T T + + P+ P P P P + P+ +
Sbjct: 3275 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 3329
Query: 396 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 445
T + GT+ P T +P P ++ + P G +
Sbjct: 3330 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3389
Query: 446 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 500
+ P ++ P G ++ T P VTP TP P +TP T
Sbjct: 3390 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 3447
Query: 501 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 557
V P P G ++ + P P Q + GT P
Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507
Query: 558 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 616
P + + TP+ P+ +P P +P Q T P + TP
Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567
Query: 617 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 671
T + V PTP P + +P T + + TP P
Sbjct: 3568 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3619
Query: 672 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 730
PT P+ T + P T + T + + +P P P + +P + V
Sbjct: 3620 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3679
Query: 731 RPRFSATRTGLQAHVWRP 748
+ T TG Q P
Sbjct: 3680 P---TPTPTGTQTPTTTP 3694
Score = 62.0 bits (149), Expect = 2e-09
Identities = 114/558 (20%), Positives = 174/558 (31%), Gaps = 67/558 (12%)
Query: 222 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 281
+P P G PT P + P Q PTTT + + ++P
Sbjct: 3610 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 3658
Query: 282 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 341
P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G
Sbjct: 3659 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 3711
Query: 342 EPPAPPSAAAMTSTASIFLSAPLRPSARP------EAPAPGPGAPEPPSAREQRISVPAA 395
P P T T + + P+ P P P P + P+ +
Sbjct: 3712 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITT 3766
Query: 396 RTGILQEARRRGTRKQMFRPGKEETKNSPNP----------ELLSLVQNLDEKPRAGGAE 445
T + GT+ P T +P P ++ + P G +
Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3826
Query: 446 SGPEEDALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPP 500
+ P ++ P G ++ T P VTP TP P +TP T
Sbjct: 3827 T-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTT 3884
Query: 501 VAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFAKRQSRADRYVVEGTPGPG 557
V P P G ++ + P P Q + GT P
Sbjct: 3885 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3944
Query: 558 LGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 616
P + + TP+ P+ +P P +P Q T P + TP
Sbjct: 3945 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4004
Query: 617 KQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFS-TPAP---- 671
T + V PTP P + +P T + + TP P
Sbjct: 4005 TP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4056
Query: 672 QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 730
PT P+ T + P T + T + + +P P P + +P + V
Sbjct: 4057 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4116
Query: 731 RPRFSATRTGLQAHVWRP 748
+ T TG Q P
Sbjct: 4117 P---TPTPTGTQTPTTTP 4131
Score = 60.5 bits (145), Expect = 6e-09
Identities = 135/636 (21%), Positives = 203/636 (31%), Gaps = 101/636 (15%)
Query: 198 PPRAQSAPPEAAVL--PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQR 255
PP +PP PP+ P+P + P P TP P+ + P T
Sbjct: 1557 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT---TPSPPTTTTTTPP 1613
Query: 256 PTTTSV--IFRPLAPKRANDSLGGLS-PAPPPFLSSQGP-----------TPLPSFTSGV 301
PTTT P+ P + +L + P+PPP ++ P TP P T+
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673
Query: 302 ------------------PSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEP 343
P+ + SP+T SS T T+ PS P T P P
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP 1733
Query: 344 ---PAPPSAAAMT----STASIFLSAPLRPSARPEAPAP----GPGAPEPP--------S 384
P+PP+ T +T+S + PL PS P +P P P P
Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLD 1793
Query: 385 AREQRISVPAARTGILQE------ARRRGTRKQMFRP---GKEETKNSPNPELLSLVQNL 435
+ + P T ++ + A R M+ G+ + + + +N
Sbjct: 1794 SGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNE 1853
Query: 436 DEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKT-----P 490
D+KP GG + + C + + T + TP T P+ T P
Sbjct: 1854 DQKP--GGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTP 1911
Query: 491 PPM---TPKTPP-----PVAPKPPSRGLLDGLVNGAASSAGI---PEPPRLQGRGGELFA 539
P TP T P V P P G ++ + P P Q
Sbjct: 1912 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1971
Query: 540 KRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIR-APPPIAYNPLLSPFFP 598
+ GT P P + + TP+ P+ +P P +P
Sbjct: 1972 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2031
Query: 599 QAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTA 658
Q T P + TP T + V PTP P + +P T
Sbjct: 2032 QTPTTTPITTTTTVTPTPTP--------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2083
Query: 659 RVQEIRRFS-TPAP----QPTAEPL-APTVLAPRAATTLDEPIWRTELASAPVPSPAPPP 712
+ + TP P PT P+ T + P T + T + + +P P P
Sbjct: 2084 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2143
Query: 713 EAPRGLGASPSSCGFQVARPRFSATRTGLQAHVWRP 748
+ +P + V + T TG Q P
Sbjct: 2144 TGTQTPTTTPITTTTTVTP---TPTPTGTQTPTTTP 2176
Score = 59.3 bits (142), Expect = 1e-08
Identities = 70/289 (24%), Positives = 87/289 (30%), Gaps = 63/289 (21%)
Query: 475 PHVTPKTPPPMAPKTPPPMTPKTPPPVA-PKPP-SRGLLDGLVNGAASSAGIPEPPRLQG 532
P T TPPP +PP T TPPP P PP S + P PP
Sbjct: 1425 PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTT-- 1482
Query: 533 RGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSP------TPSLPPSWKYSP---NIRA 583
+ + TP P P P + +P T +LPP+ SP
Sbjct: 1483 ----------TPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTT 1532
Query: 584 PPPIAYN--PLLSPFFPQAART-LPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCF 640
PPP P +P P + T LP + P T
Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT------------------------- 1567
Query: 641 DEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVL----------APRAATT 690
TP P + SP T +T P PT P PT +P T
Sbjct: 1568 --TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625
Query: 691 LDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVARPRFSATRT 739
+ P T L PSP P +PS P + T T
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT 1674
Score = 55.8 bits (133), Expect = 1e-07
Identities = 63/246 (25%), Positives = 79/246 (32%), Gaps = 23/246 (9%)
Query: 477 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGE 536
+T +PP P PP T PP P PP+ P PP
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPT------TTTTTPPPTTTPSPPITTTTTP- 1448
Query: 537 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSP---NIRAPPPIA--YNP 591
+ + TP P P P P+ TPS PP+ SP PPP P
Sbjct: 1449 --PPTTTPSPPISTTTTPPPTTTPSP--PTTTPS-PPTTTPSPPTTTTTTPPPTTTPSPP 1503
Query: 592 LLSPFFPQAA-RTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPI 650
+P P A+ TLP + P T T +PPT P
Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP- 1562
Query: 651 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPR-AATTLDEPIWRTELASAPVPSPA 709
SP +TP+P T P PT+ TT P T P +P+
Sbjct: 1563 ---SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619
Query: 710 PPPEAP 715
PP P
Sbjct: 1620 PPTTTP 1625
Score = 55.1 bits (131), Expect = 2e-07
Identities = 83/395 (21%), Positives = 128/395 (32%), Gaps = 42/395 (10%)
Query: 222 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 281
+P P G PT P + P Q PTTT + + ++P
Sbjct: 3909 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----------TTTTVTPT 3957
Query: 282 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 341
P P +Q PT P T+ + P TP ++ P+T T+++ P P TP G
Sbjct: 3958 PTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTV-TPTP----TPTGTQ 4010
Query: 342 EPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVP-AARTGIL 400
P P T T + + P+ P P+ + + P T +
Sbjct: 4011 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4070
Query: 401 QEARRRGTRKQMFRPGKEETKNSPNPEL----------LSLVQNLDEKPRAGGAESGPEE 450
GT+ P T +P P ++ + P G ++ P
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTT 4129
Query: 451 DALSLGAEACNFMQPVGARSYKTLP-----HVTPKTPPPMAPKTPPPMTPKTPPPVAPKP 505
++ P G ++ T P VTP TP P +TP T V P P
Sbjct: 4130 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTP 4188
Query: 506 PSRGLLDGLVNGAASSAGIPE-----PPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGP 560
G G S+A I E PP + + + T P +
Sbjct: 4189 TPTGTQTGPPT-HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247
Query: 561 RPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSP 595
+P TP+ P + + PP +P +P
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTP 4282
Score = 54.7 bits (130), Expect = 3e-07
Identities = 78/313 (24%), Positives = 113/313 (36%), Gaps = 46/313 (14%)
Query: 222 SPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPA 281
+P P G PT P + P TP G + TT+ I G +P
Sbjct: 4116 TPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174
Query: 282 PPPFLSSQGPTPLPSFT---SGVPSHA--------------PVSGSPSTPRS-SGPVTAT 323
P ++ TP P+ T +G P+H P S +P T RS S P+T +
Sbjct: 4175 TTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 4234
Query: 324 SSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGP--GAPE 381
++L P P + PP+ P+A TS P ++ P P G G+
Sbjct: 4235 TTLLSTLP--PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSS 4292
Query: 382 PPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKN-SPNPELLSLVQNLDEKPR 440
P+ + + +A T T + P T P P + + L++
Sbjct: 4293 APTPSTVQTTTTSAWTP---------TPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYY 4343
Query: 441 AGGAE--SGPEED-------ALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK-TP 490
A G E +G D +LS E N+ P + P + TP P P TP
Sbjct: 4344 APGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCP---STPSPTPTPSKSTPTPSKPSSTP 4400
Query: 491 PPMTPKTPPPVAP 503
TP T PP P
Sbjct: 4401 SKPTPGTKPPECP 4413
Score = 43.9 bits (102), Expect = 6e-04
Identities = 59/242 (24%), Positives = 79/242 (32%), Gaps = 72/242 (29%)
Query: 197 SPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 256
+P Q+ PP AP+A P + TP S S + L P
Sbjct: 4189 TPTGTQTGPPTHTST------APIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242
Query: 257 -----TTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSP 311
T+T+ P AP + GG + +PPP ++ P G P+ +GS
Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTS---GGHTLSPPPSTTTSPP--------GTPTRGTTTGSS 4291
Query: 312 STPRSSGPVTATSSLYIPAPSRPVTP------GGAPEPP-------------AP------ 346
S P S T T+S + P P+ TP G P P AP
Sbjct: 4292 SAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYN 4351
Query: 347 -------------------------PSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPE 381
PS + T T S P +PS+ P P PG PE
Sbjct: 4352 GTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPE 4411
Query: 382 PP 383
P
Sbjct: 4412 CP 4413
Score = 35.8 bits (81), Expect = 0.15
Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 3/81 (3%)
Query: 645 PTPGPIASGS--PKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS 702
P+P P ++ + P T +TP P T P T P TT PI T
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI-STTTTP 1464
Query: 703 APVPSPAPPPEAPRGLGASPS 723
P +P+PP P +PS
Sbjct: 1465 PPTTTPSPPTTTPSPPTTTPS 1485
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 72.4 bits (176), Expect = 1e-12
Identities = 123/493 (24%), Positives = 164/493 (33%), Gaps = 124/493 (25%)
Query: 255 RPTTTSVIFRPLAPKR-------ANDSLGGLSPAPPPFLSSQGPTPLPSFT-SGVPSHAP 306
RPT +PL P+R A D L PP ++ GP +F S P H P
Sbjct: 719 RPTAP----KPLLPRREESEAVEAGDPPEELRSLPPDMVA--GPRLPDTFLGSATPLHFP 772
Query: 307 VSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRP 366
S PS S+GP Y+ P P T G + L P P
Sbjct: 773 PSPFPS---STGP----GPHYLSGPLPPGTYSGPTQ-----------------LIQPRAP 808
Query: 367 SARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNP 426
APGP P+ + VP ++SP
Sbjct: 809 GPHAMPVAPGPALYPAPAYTPELGLVP---------------------------RSSPQH 841
Query: 427 ELLSLVQ-NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPM 485
++S + P G S P G E ++P T+ + P
Sbjct: 842 GVVSSPYVGVGPAPPVAGLPSAPPPQFS--GPELAMAVRPATT----TVDSIQAPIPSHT 895
Query: 486 APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRA 545
AP+ P TP PPP P PP + L A + IP Q
Sbjct: 896 APRPNP--TPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPA---------------QHHF 938
Query: 546 DRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLP 605
+ G P P +GP+P+ P P PS + P P +P L P PQA LP
Sbjct: 939 SSGIPAGFPAPRIGPQPQ---PHPQPHPSQAFGPQPPQQPLPLQHPHLFP--PQAPGLLP 993
Query: 606 KAQSQGPRATPKQGIKALDFMRHQPYQLKTAMF---CFDEVP--------PTPGPIASGS 654
QS P A P+ G+ + P L T ++ D +P P+PGP
Sbjct: 994 P-QSPYPYA-PQPGV-----LGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPH 1046
Query: 655 PKTARVQEIRRFSTPAPQPTAEPLAPTV--LAPRAATTLDEPIWRTELASAPVPSPAPPP 712
P A P P+ P+ P L R ++ + L +P PSP P P
Sbjct: 1047 PPLAY----------GPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGP 1096
Query: 713 EAPRGLGASPSSC 725
PR A P C
Sbjct: 1097 VPPRPPAAEPPPC 1109
Score = 65.1 bits (157), Expect = 2e-10
Identities = 85/303 (28%), Positives = 118/303 (38%), Gaps = 56/303 (18%)
Query: 177 STQELARVEPAAMLNGEGLQSPPRAQSAP---PEAAVLPPS-PLPAPVASPRPFQPGGGA 232
S ELA A + +Q+P + +AP P A PP P+P P P P+ GA
Sbjct: 869 SGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGA 928
Query: 233 PTPAPSIFNRS--------ARPFTPGLQGQRPTTTSVIFRP-------------LAPKRA 271
P P+ + S A P Q S F P L P +A
Sbjct: 929 KQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQA 988
Query: 272 NDSLGGLSP---APPPFLSSQGPTPLPSFTSGVPSHAPVSG--------SPSTPRSSGPV 320
L SP AP P + Q P PL + P+ P+ SP P+ P
Sbjct: 989 PGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPP 1048
Query: 321 TATSSLYIPAPS-RPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGA 379
A Y PAPS RP+ P AP PS+A ++ S L PS P +P PGP
Sbjct: 1049 LA----YGPAPSTRPMGPQAAPLTIRGPSSAGQSTP-----SPHLVPSPAP-SPGPGPVP 1098
Query: 380 PEPPSARE----QRISVPAARTGILQEARRRGTR-----KQMFRPGKEETKNSPNPELLS 430
P PP+A +R + A E++ GT+ + + +P K + P+ L
Sbjct: 1099 PRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALR 1158
Query: 431 LVQ 433
L++
Sbjct: 1159 LIE 1161
Score = 52.8 bits (125), Expect = 1e-06
Identities = 86/363 (23%), Positives = 119/363 (32%), Gaps = 62/363 (17%)
Query: 211 LPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTP--GLQGQRPTTTSVIFRPLAP 268
LPP P +P PG A AP A +TP GL + V+ P
Sbjct: 791 LPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVG 850
Query: 269 KRANDSLGGLSPAPPPFLSSQ--------GPTPLPSFTSGVPSH-AP-VSGSPSTPRSSG 318
+ GL APPP S T + S + +PSH AP + +P+ P
Sbjct: 851 VGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCF 910
Query: 319 PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEA-PAP-- 375
PV P P+ P GA +P P + + F + + P +P P P
Sbjct: 911 PVPPPQ----PLPTPYTYPAGAKQP-IPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQ 965
Query: 376 --GPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQ 433
GP P+ P + P G+L P + +P P +L
Sbjct: 966 AFGPQPPQQPLPLQHPHLFPPQAPGLL--------------PPQSPYPYAPQPGVLGQ-- 1009
Query: 434 NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGAR------SYKTLPHVTPKTPP---- 483
P GP +D L + A F P + +Y P P P
Sbjct: 1010 --PPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPL 1067
Query: 484 ------------PMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQ 531
P P P P PV P+PP+ L GAA++ + P Q
Sbjct: 1068 TIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQ 1127
Query: 532 GRG 534
G
Sbjct: 1128 HGG 1130
Score = 37.7 bits (86), Expect = 0.040
Identities = 64/246 (26%), Positives = 85/246 (34%), Gaps = 64/246 (26%)
Query: 480 KTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFA 539
K PP P P P+ P+ A AG P P L+ ++ A
Sbjct: 713 KKKPPPRPTAPKPLLPRRE-----------------ESEAVEAGDP-PEELRSLPPDMVA 754
Query: 540 KRQSRADRYVVEGTP---GPGLGPRPRSPSP---TPSLPPSWKYSP----NIRAPPPIAY 589
+ D ++ TP P P P P + LPP P RAP P A
Sbjct: 755 GPR-LPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAM 813
Query: 590 NPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGP 649
P A P+ PR++P+ G+ + PY V P P
Sbjct: 814 PVAPGPALYPAPAYTPEL-GLVPRSSPQHGVVS------SPY-----------VGVGPAP 855
Query: 650 IASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWR---TELASAPVP 706
+G P S P PQ + LA +A R ATT + I + A P P
Sbjct: 856 PVAGLP-----------SAPPPQFSGPELA---MAVRPATTTVDSIQAPIPSHTAPRPNP 901
Query: 707 SPAPPP 712
+PAPPP
Sbjct: 902 TPAPPP 907
Score = 35.0 bits (79), Expect = 0.26
Identities = 34/116 (29%), Positives = 42/116 (36%), Gaps = 20/116 (17%)
Query: 282 PPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAP 341
PPP PL S + +H P P+++ + RP PGG
Sbjct: 1463 PPPC------KPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRP--PGGLE 1514
Query: 342 ----------EPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAP--GPGAPEPPSA 385
EPP P A+ ST S P S PEAP P P PE PS+
Sbjct: 1515 SPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSS 1570
Score = 34.3 bits (77), Expect = 0.44
Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 14/108 (12%)
Query: 473 TLPHVTP---KTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPR 529
+LP TP +PPP++ P PK PPV P+ PS G + AS PE
Sbjct: 1533 SLPESTPIPSSSPPPLSSPLPEAPQPKEEPPV-PEAPSSGPPSSSLELLASLT--PEAFS 1589
Query: 530 LQG--RGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSW 575
L RG + +K ++ G GL S P L P W
Sbjct: 1590 LDSSLRGKQRMSKHN------FLQAHNGQGLRATRPSDDPLSLLDPLW 1631
Score = 33.1 bits (74), Expect = 0.97
Identities = 27/85 (31%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Query: 286 LSSQGPTPLPSFTSGVPSHAPVSGSP--STPRSSGPVTATSSLYIPAPSRPVTPGGAPEP 343
LS + P L S + +P A G P S P S+ P+ ++S + +P P P EP
Sbjct: 1505 LSIRPPGGLESPVASLPGPAEPPGLPPASLPEST-PIPSSSPPPLSSPL-PEAPQPKEEP 1562
Query: 344 PAPPSAAAMTSTASIFLSAPLRPSA 368
P P + ++ ++S+ L A L P A
Sbjct: 1563 PVPEAPSSGPPSSSLELLASLTPEA 1587
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 72.4 bits (176), Expect = 1e-12
Identities = 137/572 (23%), Positives = 202/572 (35%), Gaps = 131/572 (22%)
Query: 177 STQELARVEPAAMLNGEGLQSPPR----AQSAPPEAA---VLPP---SPLPAPVASPRPF 226
S + RV P LNG PP +Q+ P A + PP P+P+ +S F
Sbjct: 144 SARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRF 203
Query: 227 QPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFL 286
P G AP+PAP P P + P+ + A R++ L P P
Sbjct: 204 LPRGNAPSPAP--------PPPPAISLNAPS-----YNWGAALRSSLVPSDLGSPPAPHA 250
Query: 287 SSQGPTPLPSF-TSGVPSHAPVSGSPSTPRSSGPVT----ATSSLYIPAPSRPVTPGGAP 341
SS P+ P F S + P+ S + P GP + +++++++P P+ GGAP
Sbjct: 251 SSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPL--GGAP 308
Query: 342 E---PPAPP-SAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAART 397
P APP A+++ S A+ PL P + + P AP A+ +
Sbjct: 309 TVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS------------ASHS 356
Query: 398 GILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGA 457
L+ ++RR R P + L++ GP+
Sbjct: 357 SSLRPSQRRPRRP---------------PTVFRLLEG-----------RGPQTPR----- 385
Query: 458 EACNFMQPVGARSYKTLPHVTPKTPPPMA-PKTPPPMTPKTPPPVAPKPPSRGLLDGLVN 516
++ P P P + P+ P+ P + P DG N
Sbjct: 386 --------------RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFN 431
Query: 517 GAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWK 576
S A +P PP L G+P P+PR P PSLP +
Sbjct: 432 LLGSDAHLPPPPTLS-------------------SGSP-----PQPRHPI-QPSLPGTTS 466
Query: 577 YS----PNIRAPPPIAYNPLL-SPFFPQAARTLPKAQSQGPRATPKQGIKALDF-MRHQP 630
S P APP + P++ SP + L P G +A F Q
Sbjct: 467 GSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQG 526
Query: 631 YQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFST---PAPQPTAEPLAPTVLAPRA 687
L A F + P P++ G P + + F QP EPL P P
Sbjct: 527 LALSGAGFP-GMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGP 585
Query: 688 ATTLDEPIWRTELASAPVPSP----APPPEAP 715
EP + L ++ +P P PPP AP
Sbjct: 586 PLAPGEPEGPSLLVASLLPPPPSDLLPPPSAP 617
Score = 61.6 bits (148), Expect = 3e-09
Identities = 149/602 (24%), Positives = 202/602 (33%), Gaps = 145/602 (24%)
Query: 193 EGLQSPPRAQSAPPEAAVL---PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTP 249
EG +PP S+ AA PP P P+ + RP A P+ S + S RP
Sbjct: 311 EGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRP-----RAQAPSAS-HSSSLRP--- 361
Query: 250 GLQGQRPTTTSVIFR------PLAPKRANDSLGGLSPAP-----------PPFLSSQG-P 291
+RP +FR P P+R+ P P P LS G P
Sbjct: 362 --SQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLP 419
Query: 292 TPLPSFTSGV------PSHAPV-----SGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGA 340
TP PS + G +H P SGSP PR P+ PS P T G+
Sbjct: 420 TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRH--PIQ---------PSLPGTTSGS 468
Query: 341 ----PEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAAR 396
P PAPP+A S A + S L+ + GP P PP A + P+
Sbjct: 469 LSSVPGAPAPPAA----SKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPE 524
Query: 397 TGI-LQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSL 455
G+ L A G + P + P P L L +L GG + PE
Sbjct: 525 QGLALSGAGFPGMLGALPLP---LSLGQPPPSPL-LNHSLFGVLTGGGGQPPPEP----- 575
Query: 456 GAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKP---------- 505
+ P G P +A PPP + PPP AP
Sbjct: 576 ------LLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLL 629
Query: 506 ---PSRGLLDGLVNGAASSAGIP----------------EPPRLQGRGGELFAKRQSRAD 546
P+ G +G GA +G P PP L L A A
Sbjct: 630 ALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLA-----AT 684
Query: 547 RYVVEGTP-------GPGLGPRPRSPSPTPSLPP---SWKYSPNIRAPPPIAYNPLLSPF 596
GTP P GP P S T + P S +P+ PP +PLL
Sbjct: 685 LDPPSGTPPQPCVLSAPQPGP-PTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLG-- 741
Query: 597 FPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVP--PTPGPIA-SG 653
A G ++ AL + P L + +P P P++ +
Sbjct: 742 ----------ASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEAS 791
Query: 654 SPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPE 713
SP +Q ++ P +P AP + A+ L+ R L++ P +P P
Sbjct: 792 SPLACLLQSLQ-------IPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPP 844
Query: 714 AP 715
P
Sbjct: 845 VP 846
Score = 56.6 bits (135), Expect = 8e-08
Identities = 121/501 (24%), Positives = 165/501 (32%), Gaps = 109/501 (21%)
Query: 184 VEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRS 243
++P+ G S APP A+ P P P + G G P P +
Sbjct: 457 IQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGE 516
Query: 244 ARPFT-------------PGLQGQRPTTTSVIFRPLAPKRANDSL------GGLSPAPPP 284
A PF PG+ G P S+ P +P N SL GG P P P
Sbjct: 517 AFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPL-LNHSLFGVLTGGGGQPPPEP 575
Query: 285 FL---SSQGPTPLPSFTSG----VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTP 337
L GP P G V S P S P S P + + ++P + T
Sbjct: 576 LLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTA 635
Query: 338 G---------GAPE---------------PP--APPSAAAMTSTASIFLSAPLRP-SARP 370
G G P PP APP+ A+ S L+A L P S P
Sbjct: 636 GDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSA---LLAATLDPPSGTP 692
Query: 371 EAP----APGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRP-------GKEE 419
P AP PG PP++ + + + + G Q+ P G
Sbjct: 693 PQPCVLSAPQPG---PPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLS 749
Query: 420 TKNSPNPELLSLVQ--------NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSY 471
+ S L SL+Q L + GG P +A S AC
Sbjct: 750 SLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASS--PLACLLQSLQIPPEQ 807
Query: 472 KTLPHVTPKTPPPMAPKTP--PPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPR 529
P + P++P P PP++ PP +P PP LL G +G G
Sbjct: 808 PEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRG---GGG 864
Query: 530 LQGRGGELFAKR------QSRADRYVVE-GTPGPGLGPRPRSPSPT-------------- 568
L+G GE R + R ++ GT G G RSP T
Sbjct: 865 LRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGA 924
Query: 569 --PSLPPSWKYSPNIRAPPPI 587
PP +S +++ PP +
Sbjct: 925 EPKDPPPPGPHSEDLKVPPGV 945
Score = 45.8 bits (107), Expect = 1e-04
Identities = 75/276 (27%), Positives = 95/276 (34%), Gaps = 71/276 (25%)
Query: 460 CNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKT--PPPVAPKPPSRGLLDGLVNG 517
C+ P S + V+P P P PP TP P + P+PPS V+
Sbjct: 121 CSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPS-------VSQ 173
Query: 518 AASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKY 577
A P L G GG LF R AD G+ P PR +PSP P PP
Sbjct: 174 AF--------PTLAGPGG-LFPPR--LADPVPSGGSSSPRFLPRGNAPSPAPPPPP---- 218
Query: 578 SPNIRAPPPIAYN---PLLSPFFPQ--AARTLPKAQSQGPRATPKQGIKALDFMRHQPYQ 632
+ ++ AP +YN L S P + P A S P P
Sbjct: 219 AISLNAP---SYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPP---------------- 259
Query: 633 LKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQP---TAEPLAPTVLAPRAAT 689
C D + P P P ++ P PA QP +A P VL P
Sbjct: 260 ---LFHCSDALTPPPLPPSNNLP---------AHPGPASQPPVSSATMHLPLVLGPLGGA 307
Query: 690 TLDE-----PIWRTELASAPVPS---PAPPPEAPRG 717
E P + L SA + P PPP +G
Sbjct: 308 PTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQG 343
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 71.6 bits (174), Expect = 2e-12
Identities = 141/563 (25%), Positives = 188/563 (33%), Gaps = 91/563 (16%)
Query: 194 GLQSPPRAQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 253
GLQ P PP ++PP P + P P+ P G P P +R R P G
Sbjct: 234 GLQ-PSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSG 292
Query: 254 QRPTTTSVIFRPLAPKRAN------------DSLGGLSPA---PPPFLSSQGPTPLPSFT 298
+ RP K N D G S S
Sbjct: 293 PPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDE 352
Query: 299 SGVPSHAP---VSGSPSTPRSSG------------PVTATSSLYIPAPSRPVTPGGAPEP 343
G H SG P + G P TA + P + P P AP+P
Sbjct: 353 EGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPP--APKP 410
Query: 344 PAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA 403
P PP P R + PAP E + R++R + + ++ A
Sbjct: 411 PLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAP---EDEDEAWRQRRKQSSSEISLAVERA 467
Query: 404 RRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFM 463
RRR R++ R +EE + + +L + LDEK A E A
Sbjct: 468 RRR--REEEERRMQEERRAACAEKL----KRLDEKFGAPDKRLKAEPAA----------- 510
Query: 464 QPVGARSYKTLPHVTPKTPPPMAPKTPPPM---TPKTPPPV-APKPPSRGLLDGLVNGAA 519
P A S P PK P AP PPP TP+T P A PP++ +
Sbjct: 511 -PPAAPSTPAPPPAVPKELP--APPAPPPASAPTPETEPEEPAQAPPAQ---------ST 558
Query: 520 SSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSP 579
+ G+ P L GG + + VE GP P P P+ PP K P
Sbjct: 559 PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEP 618
Query: 580 NIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFC 639
P P +P+ ++LP + R +Q +K + Q +Q +A
Sbjct: 619 KGDGIGPTRQPPSQGLGYPKYQKSLP---PRFQRQQQEQLLKQQQQHQWQQHQQGSA--- 672
Query: 640 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 699
PPTP P + P T + PAPQ A P P L P A L P
Sbjct: 673 ----PPTPVPPSPPQPVTLG-------AVPAPQ--APPPPPKALYPGA---LGRPPPMPP 716
Query: 700 LASAPVPSPAPPPEAPRGLGASP 722
+ P PP PR L P
Sbjct: 717 MNFDPRWMMIPPYVDPRLLQGRP 739
Score = 62.8 bits (151), Expect = 1e-09
Identities = 148/624 (23%), Positives = 207/624 (33%), Gaps = 131/624 (20%)
Query: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIF-----NRSARPFTPG------LQGQRP---- 256
PP P P P + P P GAP P S F P+ PG +Q P
Sbjct: 826 PPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEP 885
Query: 257 --TTTSVIFRPLAPKRANDSLGGLSPAPPP------FLSSQGPTPLPSFTSGVPSHAPVS 308
T+ + P A ++ +G PPP + GP P S G+P P
Sbjct: 886 PKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRP-GSSRRGIPPEEP-- 942
Query: 309 GSPSTPRSSGPV--TATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRP 366
G+P PR +GP+ + P +P+ G E P PP + T +
Sbjct: 943 GAP--PRRAGPIKKPPPPTKVEELPPKPLEQG--DETPKPPKPDPLKITKG-------KL 991
Query: 367 SARPEAPAPGPGAPEPPSARE---QRISVPAARTGILQE--ARRRGTRKQMFRPGKEETK 421
E P G +P P R+ +R+ + R E AR RG R G +
Sbjct: 992 GGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRG----R 1047
Query: 422 NSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLG-------AEACNFMQPVGARSYKTL 474
+ + E S + + R GG GP G +E + + R +
Sbjct: 1048 GARSREFRSYREFRGDDGRGGGT-GGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGS 1106
Query: 475 PHVTPKTPPPMAPKTPPPMTPK----TPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRL 530
+ +AP TPK T P+AP PP GA S P P R
Sbjct: 1107 ETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPP----------GAPPS---PAPARF 1153
Query: 531 QGRGGELFAKRQSRADRYVVEGTPGPGLGP--RPRSPSPTPSLPPSWKYSPNIRAPPPIA 588
RGG +F R + R G P P + P P + S P PP+ P P +
Sbjct: 1154 TARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPT--------GPLPPS 1205
Query: 589 YNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPG 648
PL P + + S G + + RH Q + + PP
Sbjct: 1206 KEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQ-------DKPPRFR 1258
Query: 649 PIASGSPKTARVQEIR-RFSTPAPQPTAEPLAPTVL---APRAATTLDEPI--------- 695
+ AR E + + PA P E TV APR A +
Sbjct: 1259 RLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQAN 1318
Query: 696 --WRTELASAPVPS------PAPPPE--APRGLGASPSSCGFQV---------------- 729
W T S+ S APPP P+ +G G V
Sbjct: 1319 EEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAK 1378
Query: 730 --ARPRFSATRTGLQAHVWRPGAG 751
++ FS+ R G++ RPG G
Sbjct: 1379 DLSKRSFSSQRPGMERQNRRPGPG 1402
Score = 55.8 bits (133), Expect = 1e-07
Identities = 124/543 (22%), Positives = 177/543 (32%), Gaps = 113/543 (20%)
Query: 170 QRQRADSSTQELARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPS---PLPAPVASP--- 223
Q +R + ++L R++ + L++ P A A P PP+ LPAP A P
Sbjct: 479 QEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPAS 538
Query: 224 ------RPFQPGGGAP---TPAPSIFNRSARPFTPGLQGQRPTTTSVIFR--PLAPKRAN 272
P +P P TP P + +A P G +T+S F P+ P+ +
Sbjct: 539 APTPETEPEEPAQAPPAQSTPTPGV---AAAPTLVSGGGSTSSTSSGSFEASPVEPQLPS 595
Query: 273 DSLGGLSPAPPPFLSSQGPTPLPSFT---SGV-PSHAPVS---GSPSTPRSSGP------ 319
P PP + P+P G+ P+ P S G P +S P
Sbjct: 596 KE----GPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQ 651
Query: 320 ------------------VTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLS 361
+A + P+P +PVT G P P APP ++
Sbjct: 652 QEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRP 711
Query: 362 APLRP-------------------SARPEAPAPGPGA-PEPPSAREQRISVPAARTGILQ 401
P+ P RP PG P RE+ S ++ +
Sbjct: 712 PPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDR 771
Query: 402 EA----RRRGT-----RKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDA 452
A R RGT + T P P L Q DE + +E+ P
Sbjct: 772 HAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPP 831
Query: 453 LSLGAEACNFMQ-----PVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPS 507
A F + P +R P P PP + + TP PP P
Sbjct: 832 PPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTP--PPKKEPPKEE 889
Query: 508 RGLLDGLVNGAASSAGI------PEPPRLQGRGGELFAKRQSRADRYV---VEGTPGPGL 558
L G G + G+ P PPR + R + R + R + G P
Sbjct: 890 TAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRA 949
Query: 559 GPRPRSPSPT--PSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATP 616
GP + P PT LPP P P +PL + K + GP+ TP
Sbjct: 950 GPIKKPPPPTKVEELPPK-PLEQGDETPKPPKPDPL----------KITKGKLGGPKETP 998
Query: 617 KQG 619
G
Sbjct: 999 PNG 1001
Score = 55.1 bits (131), Expect = 2e-07
Identities = 147/625 (23%), Positives = 194/625 (31%), Gaps = 159/625 (25%)
Query: 212 PPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRP----LA 267
PP+P+P P P QP PAP + PG G+ P + F P +
Sbjct: 673 PPTPVP-----PSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIP 727
Query: 268 PKRANDSLGGLSPAP--PPFLSSQGPTPLPSFTSGVPS------HAPV----SGSP---- 311
P L G P PP + G P SG S HAP G+P
Sbjct: 728 PYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDP 787
Query: 312 ----------STPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLS 361
+TP P+T+ + + P PP PP A+
Sbjct: 788 KLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPE--NG 845
Query: 362 APLRPSARPEAPAPGP-GAPEPPSARE-QRISVPAARTGILQEARRRGTRKQMFRPGKEE 419
AP P +R PGP P PP + E +I P + P KEE
Sbjct: 846 APGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKK----------------EPPKEE 889
Query: 420 TKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTP 479
T PE KP G G + P S + +P P
Sbjct: 890 TAQLTGPE-------AGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEP 942
Query: 480 KTPP----PMAPKTPPPMTPKTPP---------PVAPKPPSRGLLDGLVNG---AASSAG 523
PP P+ PP + PP P PKP + G + G +
Sbjct: 943 GAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGN 1002
Query: 524 IPEPPRL--------------QGRG-GELFAK-----------------------RQSRA 545
+ PRL +GRG GE FA+ R+ R
Sbjct: 1003 LSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRG 1062
Query: 546 DRYVVEGTPGPGLGPRP--RSPSPTPSLPPSWKYSPNIR-----APPPIAYNPLLSPFFP 598
D GT GP P P R+ S T S ++ P R + L+P
Sbjct: 1063 DDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDK 1122
Query: 599 QAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGP---IASG-- 653
+A +Q P A P G PP+P P A G
Sbjct: 1123 EAPTPKEGTLTQVPLAPPPPG-----------------------APPSPAPARFTARGGR 1159
Query: 654 --SPKTARVQEIRRFSTPAPQ--PTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPA 709
+P+ + R P PQ P P A + LAP+ T P + L +P P
Sbjct: 1160 VFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKS-LAPKKPPTGPLPPSKEPLKEKLIPGPL 1218
Query: 710 PPPEAPRGLGASPSSCGFQVA-RPR 733
P RG S+ G + RPR
Sbjct: 1219 SP--VARGGSNGGSNVGMEDGERPR 1241
Score = 52.8 bits (125), Expect = 1e-06
Identities = 144/655 (21%), Positives = 209/655 (31%), Gaps = 126/655 (19%)
Query: 143 RASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSP--PR 200
R +G+G G GG + RG E + + ++ R + + E +S P
Sbjct: 1061 RGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPS 1120
Query: 201 AQSAP-PEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFN-RSARPFTP-------GL 251
+ AP P+ L PL P P G P+PAP+ F R R FTP G
Sbjct: 1121 DKEAPTPKEGTLTQVPLAPP--------PPGAPPSPAPARFTARGGRVFTPRGVPSRRGR 1172
Query: 252 QGQRPTTT-----SVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPS--- 303
G RP S + LAPK+ G L P+ P P PL G +
Sbjct: 1173 GGGRPPPQVCPGWSPPAKSLAPKKP--PTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGS 1230
Query: 304 --------------HAPVSGSPSTPR--------------SSGPVTATSSLYIPAPSRPV 335
H PR S G + T P P +
Sbjct: 1231 NVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEAL 1290
Query: 336 TPGGAPEPPAPPSAAAMTSTAS-------------IFLSAPLRPSARPEAPAPGPGAPEP 382
T PAP AAA + S S+ R + AP P P
Sbjct: 1291 TT--VTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTP 1348
Query: 383 PSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAG 442
+ A GI A RG Q + + + +S P + + + +P G
Sbjct: 1349 KAVGTPGGGGGGAVPGI--SAMSRGDLSQRAKDLSKRSFSSQRPGM----ERQNRRPGPG 1402
Query: 443 GAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVA 502
G ++G + G G ++ P ++ PP + PP P PPP +
Sbjct: 1403 G-KAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPP---EERPPGLPLPPPPPS 1458
Query: 503 PKPPSRGLLDGLVNGAASSAGIPEP-PRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPR 561
R LD +++ ++ AGI + +L R G + A + PGL
Sbjct: 1459 SSAVFR--LDQVIH--SNPAGIQQALAQLSSRQGSVTAPGGHPRHK--------PGLPQA 1506
Query: 562 PRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQ--G 619
P+ PSP P P P + P F + P +G TP+ G
Sbjct: 1507 PQGPSPRP---------PTRYEPQRVNSGLSSDPHFEE-----PGPMVRGVGGTPRDSAG 1552
Query: 620 IKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLA 679
+ R + K + + +PP GS P PQ +
Sbjct: 1553 VSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEG----------PGPQAESRDTG 1602
Query: 680 PTVLAP----RAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSCGFQVA 730
L P R T +R + P P P E G S S G ++
Sbjct: 1603 TEALTPHIWNRLHTATSRKSYRPS-SMEPWMEPLSPFEDVAGTEMSQSDSGVDLS 1656
Score = 52.4 bits (124), Expect = 2e-06
Identities = 164/741 (22%), Positives = 235/741 (31%), Gaps = 161/741 (21%)
Query: 140 AGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEG-LQSP 198
AG + + G GSG GQ R + + R SS + + EP A G ++ P
Sbjct: 898 AGRKPARGVGSG--GQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKP 955
Query: 199 PRAQSAPPEAAVLPPSPLPAPVASPRPFQP----------GG-------GAPTPAPSI-- 239
P P + LPP PL +P+P +P GG G +PAP +
Sbjct: 956 P----PPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRR 1011
Query: 240 -------------------FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSP 280
+ R F G+ S FR R +D GG +
Sbjct: 1012 DYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTG 1071
Query: 281 APPPFLSSQGPTPLPSFTSG-----VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPV 335
P + +G T + + G +P GS + + A S P P
Sbjct: 1072 GPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGT 1131
Query: 336 ---TPGGAPEPPAPPSAAAMTSTA---SIFL--SAPLR-----------------PSARP 370
P P P APPS A TA +F P R P A+
Sbjct: 1132 LTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKS 1191
Query: 371 EAPAPGPGAPEPPSAREQRISV------PAAR---TGILQEARRRGTRKQMFRPGKEETK 421
AP P P PPS + + P AR G G R + R G+ + +
Sbjct: 1192 LAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQ 1251
Query: 422 NSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKT 481
+ P P L Q + R G+E P +L+L A A + + + P
Sbjct: 1252 DKP-PRFRRLKQERENAAR--GSEGKP---SLTLPASAPGPEEALTTVTVAPAPRRAAAK 1305
Query: 482 PPPMAPKTPPPMT-------------------PKTPPPVAPKPPSRGLLDGLVNGAASSA 522
P ++ + + PPPV P + G G GA
Sbjct: 1306 SPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGI 1365
Query: 523 GIPEPPRLQGRGGELFAKRQSRADRYVVE---------------------------GTPG 555
L R +L +KR + R +E G G
Sbjct: 1366 SAMSRGDLSQRAKDL-SKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTG 1424
Query: 556 PGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFF--PQAARTLPKAQSQG-P 612
PG G + PSP P + P + PPP P S F Q + P Q
Sbjct: 1425 PGRGDKRSWPSPKNRSRPPEERPPGLPLPPP---PPSSSAVFRLDQVIHSNPAGIQQALA 1481
Query: 613 RATPKQGIKAL--DFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPK--TARVQEIRRFST 668
+ + +QG RH+P + P+P P P+ + + F
Sbjct: 1482 QLSSRQGSVTAPGGHPRHKPGLPQAPQ------GPSPRPPTRYEPQRVNSGLSSDPHFEE 1535
Query: 669 PAPQPT---AEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAPPPEAPRGLGASPSSC 725
P P P ++P + P + EL PPP + LG+ P
Sbjct: 1536 PGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQ---EESLPPPHSSGFLGSKPEGP 1592
Query: 726 GFQVARPRFSATRTGLQAHVW 746
G Q A R + T L H+W
Sbjct: 1593 GPQ-AESRDTGTE-ALTPHIW 1611
Score = 51.6 bits (122), Expect = 3e-06
Identities = 148/644 (22%), Positives = 197/644 (30%), Gaps = 159/644 (24%)
Query: 196 QSPPRAQSA----PPEAAVLPPSPLPA------PVASPR--PFQPGG------------- 230
QS P++ A PPE+ LP S PA P A+P P P G
Sbjct: 92 QSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGA 151
Query: 231 -GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSS- 288
G A S+ +R +R P LQ + R A + G P+ P S+
Sbjct: 152 HGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESA-----EQSSGPGPSLRPQNSTT 206
Query: 289 ------QGPTPLPSFTSGV-PSHAPVSG-SPSTPRSSGPVTATSSLYIPAPSRPVTPGGA 340
+GP L S + H P G PS P P ++ P P P
Sbjct: 207 WRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYG 266
Query: 341 PEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAP-GPGAPEPPSAREQRISVPAARTGI 399
P+ P P PS P P G G P R+ P R I
Sbjct: 267 PQGP-------------YRYPTPDGPSRFPRVAGPRGSGPP-------MRLVEPVGRPSI 306
Query: 400 LQE-------------------ARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPR 440
L+E A + + EE + E + +
Sbjct: 307 LKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEE---GAEGHRDSQS 363
Query: 441 AGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPP-------- 492
A G E PE D + P A + + P T PP P PPP
Sbjct: 364 ASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNW 423
Query: 493 -----MTPKTPPPVAPKPPSRGLLDGLVNGAASSAGI------------PEPPRLQGRGG 535
+ PP P P SS+ I E R+Q
Sbjct: 424 GPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERR 483
Query: 536 ELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSP 595
A++ R D G P L P +P PS P APPP L +P
Sbjct: 484 AACAEKLKRLDEKF--GAPDKRLKAEPAAPPAAPSTP----------APPPAVPKELPAP 531
Query: 596 FFPQAA-----RTLPKAQSQGP--RATPKQGIKALDFM---------------RHQPYQ- 632
P A T P+ +Q P ++TP G+ A + P +
Sbjct: 532 PAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEP 591
Query: 633 ---LKTAMFCFDEV-PPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAA 688
K +EV PPT P+ PK + R+ P Q P L PR
Sbjct: 592 QLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQ---PPSQGLGYPKYQKSLPPRFQ 648
Query: 689 TTLDEPI--------WRTELASAPVPSPAPP-PEAPRGLGASPS 723
E + W+ + P+P PP P P LGA P+
Sbjct: 649 RQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPA 692
Score = 43.1 bits (100), Expect = 0.001
Identities = 127/566 (22%), Positives = 179/566 (31%), Gaps = 110/566 (19%)
Query: 185 EPAAMLNGEG---------LQSPPRAQSAPP-EAAVLPPSPLPAPVAS----PRPFQPGG 230
EP M+ G G PP+ + PP + +L LP P +S +P PG
Sbjct: 1535 EPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGP 1594
Query: 231 -------GAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAP------KRANDSLGG 277
G P I+NR + RP++ PL+P + S G
Sbjct: 1595 QAESRDTGTEALTPHIWNRLHT--ATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSG 1652
Query: 278 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTP 337
+ + +SS GP S G A G P P S P+ A P P P
Sbjct: 1653 VDLSGDSQVSS-GPCSQRSSPDGGLKGA-AEGPPKRPGGSSPLNAVPCEGPPGSEPPRRP 1710
Query: 338 GGAPE-------------PPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPS 384
AP PP P T P+RPS RP P + +
Sbjct: 1711 PPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSD 1770
Query: 385 AR-------EQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPN----PELLSLVQ 433
R + + A+ T + +R + ++KN + PE S Q
Sbjct: 1771 LRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQ 1830
Query: 434 NLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGA--------RSYKTLPHVTPKTP-PP 484
L P +GP +S GA G Y++ P P P PP
Sbjct: 1831 RL--YPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPLYLPPGPAPP 1888
Query: 485 MA----------------------PKTP------PPMTPKTPPPVAPKP-PSRGLLDGLV 515
A K P PP + P P P P LL
Sbjct: 1889 SALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQ 1948
Query: 516 NGAASSAGIPEPPRLQGRGGEL--FAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPP 573
+ + S P + G+ G L A Q V P G P +P P P
Sbjct: 1949 DLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLS 2008
Query: 574 SWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQL 633
P ++ PP +A P +P A R LP P + + + ++ Q YQ
Sbjct: 2009 LLPVGPALQ-PPSLAVRPPPAP----ATRVLPSPARPFPASLGRAELHPVELKPFQDYQK 2063
Query: 634 KTAMFCFDEVPPTPGPIASGSPKTAR 659
++ GP +S +P T R
Sbjct: 2064 LSSNL--------GGPGSSRTPPTGR 2081
Score = 33.9 bits (76), Expect = 0.57
Identities = 49/205 (23%), Positives = 72/205 (35%), Gaps = 29/205 (14%)
Query: 520 SSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSP 579
S++G PP G+ G E + P P P P+P P LPP +
Sbjct: 363 SASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGP--PAPKPPLPPPHRGPA 420
Query: 580 NIRAPPPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFC 639
PP + P P A +A Q + + + A++ R + + + M
Sbjct: 421 GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRM-- 478
Query: 640 FDEVPPTPGPIASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTE 699
A+ + K R+ E +F P + AEP AP P A +T
Sbjct: 479 ------QEERRAACAEKLKRLDE--KFGAPDKRLKAEPAAP----PAAPST--------- 517
Query: 700 LASAPVPSPAPPPEAPRGLGASPSS 724
P P PA P E P P+S
Sbjct: 518 ----PAPPPAVPKELPAPPAPPPAS 538
Score = 33.1 bits (74), Expect = 0.97
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 16/112 (14%)
Query: 198 PPRAQSAPPEAAVLPPSP-LPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRP 256
PP APP ++LP P L P + RP P PA + ARPF L R
Sbjct: 1997 PPAPPPAPPPLSLLPVGPALQPPSLAVRP------PPAPATRVLPSPARPFPASL--GRA 2048
Query: 257 TTTSVIFRPLAP-KRANDSLG--GLSPAPPPFLSSQGPT----PLPSFTSGV 301
V +P ++ + +LG G S PP S G PS SGV
Sbjct: 2049 ELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGV 2100
Score = 32.3 bits (72), Expect = 1.7
Identities = 64/261 (24%), Positives = 91/261 (34%), Gaps = 49/261 (18%)
Query: 266 LAPKRANDSLGGLS-------PAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSG 318
+AP+ SLG ++ PA P L ++ P+ S VP +G S S
Sbjct: 38 VAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPN-VSLVPKDG--TGWASKQEQSD 94
Query: 319 PVTATSSLYIPAPSRPVTPGGAP---EPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAP 375
P ++ +S P S+P+ P +P PP+A T + + + S A
Sbjct: 95 PKSSDASTAQPPESQPLPASQTPASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGD 154
Query: 376 GPGAPEPPSAREQRISVPAARTGILQE--ARRRGTRKQMFRPGKEETKNSPNPELLSLVQ 433
G G +R R P + Q+ A+ R + +Q PG SL
Sbjct: 155 G-GRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGP------------SLRP 201
Query: 434 NLDEKPRAGGAESGPEE-----DALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPK 488
R GG GP+E L G + +QP G PP P
Sbjct: 202 QNSTTWRDGGGR-GPDELEGPDSKLHHGHDPRGGLQPSG---------------PPQFPP 245
Query: 489 TPPPMTPKTPPPVAPKPPSRG 509
M P PP P PP G
Sbjct: 246 YRGMMPPFMYPPYLPFPPPYG 266
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 71.6 bits (174), Expect = 2e-12
Identities = 127/517 (24%), Positives = 173/517 (33%), Gaps = 116/517 (22%)
Query: 149 GSGLGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRA------Q 202
GSG GG +++Q Q+ D +E E + EG + RA
Sbjct: 345 GSGQGGS---------PCWKKQEQKLDDEEEEKKEEEEK---DKEGEEKEERAVAEEMMP 392
Query: 203 SAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVI 262
+A E A LPP PL P SP P P + +P P + P +P P +
Sbjct: 393 AAEKEEAKLPPPPLTPPAPSPPPPLP-PPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE 451
Query: 263 FRPLAPKRANDSLGGLSPAPPPFLSSQ---------------GPTPLPS-FTSGVPSHAP 306
+ +P + PP SQ PTP PS T G P +P
Sbjct: 452 EQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSP 511
Query: 307 VSGSPSTPRSSG-------PVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 359
ST V+A SS I P R + +PP PP S
Sbjct: 512 TVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMD----EDPPKPPKV-----EVSPV 562
Query: 360 LSAPLRPSAR-PEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKE 418
L P+ S P+ PAP P P P+ + +P R IL+E R T
Sbjct: 563 LRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWT---------- 612
Query: 419 ETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLP--- 475
SL + L P A P A A + +P+ R+ + P
Sbjct: 613 -----------SLTRELPPPPPAPPPPPAPSPPP----APATSSRRPLLLRAPQFTPSEA 657
Query: 476 ----HVTPKTPPPM-APKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRL 530
+ + TPPP+ AP+ P P PPP P PE PR
Sbjct: 658 HLKIYESVLTPPPLGAPEAPEP----EPPPADDSPAE-----------------PE-PRA 695
Query: 531 QGRGGELFAKRQSRADRYVVE------GTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAP 584
GR L R + V+ G P GP+ ++ P + P P
Sbjct: 696 VGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPP 755
Query: 585 PPIAYNPLLSPFFPQAARTLPKAQSQGPRATPKQGIK 621
P P P PQ L KA+ G + P G++
Sbjct: 756 PQPQLQP---PPSPQQMPPLEKARIAGVGSLPLSGVE 789
Score = 67.8 bits (164), Expect = 4e-11
Identities = 128/576 (22%), Positives = 197/576 (34%), Gaps = 128/576 (22%)
Query: 242 RSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLS-SQGPTPLPSFTSG 300
RS R P +G++ TT PL P R D ++P PP + +G
Sbjct: 142 RSQRGRAPRGRGRKHKTT-----PLPPPRLAD----VAPTPPKTPARKRGEEGTERMVQA 192
Query: 301 VPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFL 360
+ + +P PRS +T P SR PG P A + + A++ +
Sbjct: 193 LTELLRRAQAPQAPRSRACEPST-----PRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTI 247
Query: 361 SAPLRPSAR------------PEAPAPGPGAPEPPS------------------------ 384
P P E P PGPG P
Sbjct: 248 PKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKF 307
Query: 385 -AREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSP---NPELLSLVQNLDEKPR 440
+R +++ + G L+ + +G ++ ++ + S +P Q LD++
Sbjct: 308 VSRAKKVKMGQLSLG-LESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEE 366
Query: 441 AGGAES-----GPEEDALSLGAEACNFMQPVGARSYKTLPHV-----TPKTPPPMAPKT- 489
E G E++ ++ E M P + LP P PPP+ P +
Sbjct: 367 EKKEEEEKDKEGEEKEERAVAEE----MMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPST 422
Query: 490 --PPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPP--------RLQGRGGELFA 539
PPP+ P PPPV+P P L A PP R +GR +
Sbjct: 423 SPPPPLCPPPPPPVSPPP-----LPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPS 477
Query: 540 KRQSR-ADRYVVEGTPGPGLGPR-----PRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLL 593
+R R A R EGT P P P SPT + P S + NIR P++
Sbjct: 478 QRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVA-PKSTTFLKNIRQ----FIMPVV 532
Query: 594 SPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASG 653
S + +T + + P PK + + L+ + VP P P+ S
Sbjct: 533 SARSSRVIKTPRRFMDEDPPKPPKVEVSPV---------LRPPITTSPPVPQEPAPVPS- 582
Query: 654 SPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPI--WRTELASAPVPSPAPP 711
P+ P P L + + L EP W + P P PAPP
Sbjct: 583 ----------------PPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626
Query: 712 P---EAPRGLGASPSSCGFQVARPRFSATRTGLQAH 744
P +P A+ S + P+F+ + L+ +
Sbjct: 627 PPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIY 662
Score = 61.2 bits (147), Expect = 3e-09
Identities = 129/561 (22%), Positives = 179/561 (31%), Gaps = 106/561 (18%)
Query: 198 PPRAQSAPPEAAVLPPSPLP--APVAS-PRPFQP-GGGAPTPAPSIFNRSARPFTPGLQG 253
PP + P + VL P +P+ + P +P G AP PAP F+ AR P
Sbjct: 1814 PPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFS-GARIKVPNYSP 1872
Query: 254 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPST 313
R RPL GG+S GP P P S + H P G P
Sbjct: 1873 SR--------RPL---------GGVS---------FGPLPSPGSPSSLTHHIPTVGDPDF 1906
Query: 314 PRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAP 373
P S L AP P + +P P T+ + P P P
Sbjct: 1907 PAPPRRSRRPSPL---APRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGP 1963
Query: 374 APGPGAPEP--PSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSL 431
AP P PE P + + + + A GT P +EE
Sbjct: 1964 APSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGT-----EPFQEE------------ 2006
Query: 432 VQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPHVTPKTPPPMAPKTPP 491
+ G + GP + + + ++ P VT + P +AP
Sbjct: 2007 ---IVAAGAMGSSHGGPGDSSEEESSPTSRYIH---------FP-VTVVSAPGLAPS--- 2050
Query: 492 PMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVE 551
P P LDG+ +G S A + PR QG V
Sbjct: 2051 ---------ATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQG--------TPPSGPGVVRA 2093
Query: 552 GTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLLSPFFPQAARTLPKAQSQG 611
G G G R R P PS + N+ P P P SQG
Sbjct: 2094 GVLG-AAGDRARPPEDLPSEIVDFVLK-NLGGPGDGGAGPREESLPPAPPLANGSQPSQG 2151
Query: 612 PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPPTPGPIASGSPKTARVQEIRRF----- 666
A+P + ++ P ++ P P P + K V ++ +
Sbjct: 2152 LTASPADPTRTFAWLPGAPGVRVLSL------GPAPEPPKPATSKIILVNKLGQVFVKMA 2205
Query: 667 --STPAPQPTAEPLAPTVLAPRAAT--TLDEPIWRTELASAPVPSPAPPPEAP---RGLG 719
P P P +P P ++P A T TL L V PAPPP P L
Sbjct: 2206 GEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLS 2265
Query: 720 ASPSSCGFQVARPRFSATRTG 740
+ P+S Q R + +T +G
Sbjct: 2266 SGPASPPRQAIRVKRVSTFSG 2286
Score = 51.2 bits (121), Expect = 3e-06
Identities = 74/288 (25%), Positives = 103/288 (35%), Gaps = 59/288 (20%)
Query: 159 VSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPRAQS-----APPEAAVLPP 213
VS R ++ + R+ D + +VE + +L SPP Q +PP A P
Sbjct: 532 VSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPS 591
Query: 214 SPLPAP--------------------VASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQG 253
+P+P P + P P P AP+P P+ S RP L
Sbjct: 592 TPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRP----LLL 647
Query: 254 QRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPST 313
+ P T P A+ + PPP + + P P P P SP+
Sbjct: 648 RAPQFT--------PSEAHLKIYESVLTPPPLGAPEAPEPEPP---------PADDSPAE 690
Query: 314 PRSSGPVTATSSLYIP--AP--SRP----VTPGGAPEPPAPPSAAAMTSTASIFLSAPLR 365
P V T+ L +P AP + P V+P GAP P A L L
Sbjct: 691 PEPRA-VGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLL 749
Query: 366 PSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMF 413
P A P P P PPS +Q + AR + G ++MF
Sbjct: 750 PQA---LPPPQPQLQPPPSP-QQMPPLEKARIAGVGSLPLSGVEEKMF 793
Score = 42.4 bits (98), Expect = 0.002
Identities = 94/396 (23%), Positives = 128/396 (32%), Gaps = 103/396 (26%)
Query: 179 QELARVEPAAMLNGEGLQSPPRAQSAPPE------AAVL--------PPSPLPAPVAS-- 222
++L V+ E +Q P R Q PP A VL PP LP+ +
Sbjct: 2059 EQLDGVDDGTDSEAEAVQQP-RGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFV 2117
Query: 223 -PRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG---- 277
PG G P S P P G +P+ + P P R L G
Sbjct: 2118 LKNLGGPGDGGAGPR----EESLPPAPPLANGSQPSQ-GLTASPADPTRTFAWLPGAPGV 2172
Query: 278 ----LSPAPPP---------FLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATS 324
L PAP P ++ G + G P PV P P S P TS
Sbjct: 2173 RVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTIS-PTAPTS 2231
Query: 325 SLYIPAPSRPVTP-----GGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGA 379
P P V P AP PP PP ++S GP +
Sbjct: 2232 WTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSS---------------------GPAS 2270
Query: 380 PEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKP 439
P + R +R+S + R+ P +P LDE
Sbjct: 2271 PPRQAIRVKRVSTFSGRS-----------------PPAPPPYKAPR---------LDEDG 2304
Query: 440 RAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPH----VTPKTPPPMAPKTPPPMTP 495
A +E P+ L G + M+ R L ++P P+ ++P P
Sbjct: 2305 EA--SEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLP 2362
Query: 496 KTPPPVAPKPPSRGLLDGL---VNGAASSAGIPEPP 528
+ PP P P LL+ +G ASS+ EPP
Sbjct: 2363 EDGPPQVPDGPPDLLLESQWHHYSGEASSSE-EEPP 2397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.130 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,081,842
Number of Sequences: 37866
Number of extensions: 3259486
Number of successful extensions: 59910
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 587
Number of HSP's successfully gapped in prelim test: 2320
Number of HSP's that attempted gapping in prelim test: 19969
Number of HSP's gapped (non-prelim): 21532
length of query: 753
length of database: 18,247,518
effective HSP length: 110
effective length of query: 643
effective length of database: 14,082,258
effective search space: 9054891894
effective search space used: 9054891894
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.