BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4885371 H1 histone family, member 0 [Homo sapiens] (194 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4885371 H1 histone family, member 0 [Homo sapiens] 372 e-104 gi|4885381 histone cluster 1, H1b [Homo sapiens] 119 2e-27 gi|4885379 histone cluster 1, H1e [Homo sapiens] 118 3e-27 gi|4885375 histone cluster 1, H1c [Homo sapiens] 116 1e-26 gi|4885373 histone cluster 1, H1a [Homo sapiens] 112 2e-25 gi|4885377 histone cluster 1, H1d [Homo sapiens] 108 2e-24 gi|20544168 histone cluster 1, H1t [Homo sapiens] 86 2e-17 gi|5174449 H1 histone family, member X [Homo sapiens] 75 5e-14 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 57 8e-09 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 57 1e-08 gi|24475863 H1 histone family, member O, oocyte-specific [Homo s... 55 4e-08 gi|56676330 HP1-BP74 [Homo sapiens] 54 6e-08 gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Ho... 52 2e-07 gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Hom... 52 2e-07 gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 49 4e-06 gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 47 1e-05 gi|4557509 cylicin 2 [Homo sapiens] 46 2e-05 gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 46 2e-05 gi|11067749 bromodomain containing protein 3 [Homo sapiens] 46 2e-05 gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 45 3e-05 gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 45 5e-05 gi|125656165 THO complex 2 [Homo sapiens] 44 9e-05 gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens] 43 1e-04 gi|153791662 coiled-coil domain containing 71 [Homo sapiens] 42 3e-04 gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 42 3e-04 gi|11225260 DNA topoisomerase I [Homo sapiens] 42 4e-04 gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] 41 6e-04 gi|104526627 triadin [Homo sapiens] 41 7e-04 gi|109637759 calpastatin isoform f [Homo sapiens] 40 0.001 gi|56118310 nuclear casein kinase and cyclin-dependent kinase su... 40 0.001 >gi|4885371 H1 histone family, member 0 [Homo sapiens] Length = 194 Score = 372 bits (956), Expect = e-104 Identities = 194/194 (100%), Positives = 194/194 (100%) Query: 1 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKV 60 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKV Sbjct: 1 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKV 60 Query: 61 GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATP 120 GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATP Sbjct: 61 GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATP 120 Query: 121 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVK 180 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVK Sbjct: 121 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVK 180 Query: 181 PKAKSSAKRAGKKK 194 PKAKSSAKRAGKKK Sbjct: 181 PKAKSSAKRAGKKK 194 >gi|4885381 histone cluster 1, H1b [Homo sapiens] Length = 226 Score = 119 bits (298), Expect = 2e-27 Identities = 97/221 (43%), Positives = 116/221 (52%), Gaps = 31/221 (14%) Query: 3 ENSTSAPAAK-PKRAKASKKSTDH---------PKYSDMIVAAIQAEKNRAGSSRQSIQK 52 E +T AP K P + KA+KK+ P S++I A+ A K R G S +++K Sbjct: 8 ETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGLSLAALKK 67 Query: 53 YIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRL---AKSDEPK---KSVA 106 + + E +S+IKL +K LV+ G L QTKG GASGSF+L A S E K K Sbjct: 68 ALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKAKKAG 127 Query: 107 FKKTKKEIKKVATPKKASK---PKKAASKAP--TKKPKATPVKKA-----KKKLAATPKK 156 K KK ATPKKA K KKA K P KKP A VKK K K AA PKK Sbjct: 128 AAKAKKPAG--ATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAKPKK 185 Query: 157 A-KKPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK 194 A K P KA KA+KPK AKP KPKA + K A KKK Sbjct: 186 ATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK 226 >gi|4885379 histone cluster 1, H1e [Homo sapiens] Length = 219 Score = 118 bits (296), Expect = 3e-27 Identities = 91/221 (41%), Positives = 113/221 (51%), Gaps = 29/221 (13%) Query: 1 MTENSTSAPAAKP------------KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQ 48 M+E + +APAA K A A+K+ P S++I A+ A K R+G S Sbjct: 1 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA 60 Query: 49 SIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRL---AKSDEPK--- 102 +++K + + E +S+IKL +K LV+ G L QTKG GASGSF+L A S E K Sbjct: 61 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA 120 Query: 103 KSVAFKKTKKEIKKVATPKK---ASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAK- 158 K K KK PKK A+ PKK+A K P K K P A K A +PKKAK Sbjct: 121 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKK--PAAAAGAKKAKSPKKAKA 178 Query: 159 -KPKTVKAKPVKAS--KPKKAKP--VKPKAKSSAKRAGKKK 194 KPK P KA KPK AKP KPKA K A KKK Sbjct: 179 AKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK 219 >gi|4885375 histone cluster 1, H1c [Homo sapiens] Length = 213 Score = 116 bits (291), Expect = 1e-26 Identities = 89/219 (40%), Positives = 114/219 (52%), Gaps = 31/219 (14%) Query: 1 MTENSTSAPAAKP------------KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQ 48 M+E + +APAA P K+A + + P S++I A+ A K R+G S Sbjct: 1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA 60 Query: 49 SIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRL---AKSDEPK--- 102 +++K + + E +S+IKL +K LV+ G L QTKG GASGSF+L A S E K Sbjct: 61 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV 120 Query: 103 KSVAFKKTKKEIKKVATPKKA---SKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAK- 158 K K KK + PKKA + PKK+A K P KK K KK+A +PKKAK Sbjct: 121 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTP-KKAKKPAAATVTKKVAKSPKKAKV 179 Query: 159 -KPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK 194 KPK KA KPK AKP VKPK K A KKK Sbjct: 180 AKPKKAAKSAAKAVKPKAAKPKVVKPK-----KAAPKKK 213 >gi|4885373 histone cluster 1, H1a [Homo sapiens] Length = 215 Score = 112 bits (281), Expect = 2e-25 Identities = 85/198 (42%), Positives = 103/198 (52%), Gaps = 19/198 (9%) Query: 10 AAKP-KRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQI 68 A KP K A ASKK P S++IV A + K R G S +++K + + E +S+I Sbjct: 24 AKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAAAGYDVEKNNSRI 83 Query: 69 KLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKK 128 KL IK LV+ G L QTKG GASGSF+L K + +TK KVAT KA+ K Sbjct: 84 KLGIKSLVSKGTLVQTKGTGASGSFKL------NKKASSVETKPGASKVATKTKATGASK 137 Query: 129 AASKAPTKKPKATPVKKAKKKLAATPKKA---KKPKTVKAKPV-------KASKPK--KA 176 KA K+ K KK AAT K + KKPKTVK K V KA KPK KA Sbjct: 138 KLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPAKAKAVKPKAAKA 197 Query: 177 KPVKPKAKSSAKRAGKKK 194 + KPK K A KKK Sbjct: 198 RVTKPKTAKPKKAAPKKK 215 Score = 28.1 bits (61), Expect = 4.9 Identities = 22/65 (33%), Positives = 25/65 (38%) Query: 126 PKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKS 185 P AAS AP K KK K AA+ KK P + AS K+ V A Sbjct: 7 PAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALK 66 Query: 186 SAKRA 190 A A Sbjct: 67 KALAA 71 >gi|4885377 histone cluster 1, H1d [Homo sapiens] Length = 221 Score = 108 bits (271), Expect = 2e-24 Identities = 81/205 (39%), Positives = 104/205 (50%), Gaps = 28/205 (13%) Query: 11 AKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKL 70 AK A A K+ P S++I A+ A K R+G S +++K + + E +S+IKL Sbjct: 24 AKKAGATAGKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKL 83 Query: 71 SIKRLVTTGVLKQTKGVGASGSFRLAK---------------SDEPKKSVAFKKTKKEIK 115 +K LV+ G L QTKG GASGSF+L K + +P+K K K++ Sbjct: 84 GLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPKAKKAGAAKPRKPAGAAKKPKKVA 143 Query: 116 KVATPKKA-----SKPKKAASKAPTKKPKATPVKKAKKKLAATPKK-AKKPKTVKAKPVK 169 ATPKK+ K KK A+ A TKK K AKK PKK AK P KA K Sbjct: 144 GAATPKKSIKKTPKKVKKPATAAGTKK----VAKSAKKVKTPQPKKAAKSPAKAKAPKPK 199 Query: 170 ASKPKKAKPVKPKAKSSAKRAGKKK 194 A+KPK KP KAK K A KKK Sbjct: 200 AAKPKSGKPKVTKAK---KAAPKKK 221 >gi|20544168 histone cluster 1, H1t [Homo sapiens] Length = 207 Score = 86.3 bits (212), Expect = 2e-17 Identities = 62/195 (31%), Positives = 95/195 (48%), Gaps = 6/195 (3%) Query: 1 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKV 60 M + T KP ++ + + S +I A+ + R G S +++K + + Sbjct: 17 MEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVGMSLVALKKALAAAGYD 76 Query: 61 GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPK--KSVAFKKTKKEIKKVA 118 E +S+IKLS+K LV G+L QT+G GASGSF+L+K PK +S A K + KK+ Sbjct: 77 VEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKSTRSKAKKSVSAKTKKLV 136 Query: 119 TPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKP 178 + + PK A + KKP+AT K + A K K K + PVKA + K+K Sbjct: 137 LSRDSKSPKTAKTNKRAKKPRATTPKTVRSGRKA---KGAKGKQQQKSPVKA-RASKSKL 192 Query: 179 VKPKAKSSAKRAGKK 193 + + K KK Sbjct: 193 TQHHEVNVRKATSKK 207 >gi|5174449 H1 histone family, member X [Homo sapiens] Length = 213 Score = 74.7 bits (182), Expect = 5e-14 Identities = 67/203 (33%), Positives = 88/203 (43%), Gaps = 25/203 (12%) Query: 1 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKS-HYK 59 +T+ SA + K+ K SKK KYS ++V I+ R GSS I K + Sbjct: 21 VTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRRLGERNGSSLAKIYTEAKKVPWF 80 Query: 60 VGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVAT 119 +N + +K SIK LV L Q KG GA+GSF+L + KK + ++ Sbjct: 81 DQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLNR----------KKLEGGGERRGA 130 Query: 120 PKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKK----------AKKPKTVKAKPVK 169 P A+ P A KA P A ++A KK A K AKK K KAK Sbjct: 131 PAAATAPAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQRSHKKGAGAKKDKGGKAKKTA 190 Query: 170 ASKPKK----AKPVKPKAKSSAK 188 A+ KK AKP PK K Sbjct: 191 AAGGKKVKKAAKPSVPKVPKGRK 213 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 57.4 bits (137), Expect = 8e-09 Identities = 66/210 (31%), Positives = 95/210 (45%), Gaps = 23/210 (10%) Query: 8 APAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKS--HYKVGENAD 65 +P AK KS K + A AE ++ ++ KS K E A Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605 Query: 66 SQIKLSIKRLVT--TGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVA-TPKK 122 S +K K + V ++ K S AKS +++ + +K K K+ A +P+K Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665 Query: 123 ASKPKKAASKAPTK-----KPKATPVKKAK---KKLAATPKKAKKPKTVKAK-------P 167 A P KA +K+P K K +A +KAK K+ A +P+KAK P +AK P Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725 Query: 168 VK--ASKPKKAK-PVKPKAKSSAKRAGKKK 194 VK A P+KAK PVK +AKS K +K Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755 Score = 57.0 bits (136), Expect = 1e-08 Identities = 62/220 (28%), Positives = 96/220 (43%), Gaps = 30/220 (13%) Query: 3 ENSTSAPAAK-PKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVG 61 E + S P AK P++ +A + A +A+ S + + +K K Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSP 615 Query: 62 ENADSQIKLSIKRLVTTGVLKQTKGVGA--SGSFRLAKSDEPKKSVAFKKTKKEIKKVA- 118 A S +K K ++ K + S AKS E +++ + +K K +K A Sbjct: 616 AEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675 Query: 119 TPKKASKPKKAASKAPTK-------------------KPKATPVKKAK---KKLAATPKK 156 +P+KA P KA +K+P K K +A +KAK K+ A TP+K Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK 735 Query: 157 AKKPKTVKAK-PVKASKPKKAKPV---KPKAKSSAKRAGK 192 AK P +AK P KA P+KAK + P+AK+ AK + Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775 Score = 54.7 bits (130), Expect = 5e-08 Identities = 55/199 (27%), Positives = 89/199 (44%), Gaps = 17/199 (8%) Query: 3 ENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGE 62 E +P + ++ A KS + K A +++ + +++ + ++ E Sbjct: 513 EKEAKSPVKEEAKSPAEAKSPE--KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE 570 Query: 63 NADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSD--EPKKSVAFKKT--KKEIK--- 115 A S ++ + ++ K + S AKS E KS A K+ K+E K Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630 Query: 116 KVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAK-PVKASKPK 174 +V +P+KA P K +K+P K K +K+ A +P+KAK P +AK P KA P Sbjct: 631 EVKSPEKAKSPTKEEAKSPEK------AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684 Query: 175 KAKPVKP-KAKSSAKRAGK 192 KA+ P KAKS K K Sbjct: 685 KAEAKSPEKAKSPVKEEAK 703 Score = 52.4 bits (124), Expect = 2e-07 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 21/206 (10%) Query: 10 AAKPKRAKASKKS-TDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQI 68 A P++AK+ +K+ T K + A + ++ A + + +K K E A S + Sbjct: 744 AKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL 803 Query: 69 K---------LSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFK-KTKKEIKKVA 118 K + K V + V ++ K K++E K K + KK+ KK Sbjct: 804 KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE 863 Query: 119 TPKK-ASKPKKAASKAPT-KKPKATPVKKAK-----KKLAATPKK---AKKPKTVKAKPV 168 PKK A KPK K P +KPK + V+ K KK TP+K AK AKP Sbjct: 864 APKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPK 923 Query: 169 KASKPKKAKPVKPKAKSSAKRAGKKK 194 + ++ K +P KAK +K A KK+ Sbjct: 924 EKTEVAKKEPDDAKAKEPSKPAEKKE 949 Score = 48.9 bits (115), Expect = 3e-06 Identities = 55/222 (24%), Positives = 87/222 (39%), Gaps = 36/222 (16%) Query: 3 ENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGE 62 ++ A A P++AK+ K + K + + ++ E S + + +K K E Sbjct: 681 KSPVKAEAKSPEKAKSPVK--EEAKSPEKAKSPVKEE----AKSPEKAKSPVKEEAKTPE 734 Query: 63 NADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFK---KTKKEIKK-VA 118 A S +K K ++ K + + E +S A K K K +K+ V Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794 Query: 119 TPKKASKPKKAASKAPTK---------------------KPKATPVKKAKKKLAATPKKA 157 +P+KA P K +KAP K K K P K ++K ATPK Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTE 854 Query: 158 KKPKTVKAKPVKASKPK-----KAKPVKPKAKSSAKRAGKKK 194 +K + K + K PK K +P K K S A K++ Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896 Score = 48.1 bits (113), Expect = 5e-06 Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 5/119 (4%) Query: 80 VLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVA-TPKKASKPKKAASKAPTKKP 138 V ++ K + S ++ P + + +K K K+ A +P +A P+K +K+P + Sbjct: 520 VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK 579 Query: 139 KATPVKKAKKKLAATPKKAKKPKTVKAKPVK--ASKPKKAK-PVKPKAKSSAKRAGKKK 194 K K+ A +P +AK P+ K+ PVK A P +AK PVK +AKS A+ +K Sbjct: 580 SPEKAKSPAKEEAKSPAEAKSPEKAKS-PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637 Score = 45.4 bits (106), Expect = 3e-05 Identities = 34/106 (32%), Positives = 54/106 (50%), Gaps = 10/106 (9%) Query: 99 DEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPV-----KKAK---KKL 150 +E KS ++ K+ +P K A +K+P K+ +P +KAK K+ Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557 Query: 151 AATPKKAKKPKTVKAK-PVKASKPKKAK-PVKPKAKSSAKRAGKKK 194 A +P +AK P+ +AK P + P+KAK P K +AKS A+ +K Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEK 603 Score = 43.9 bits (102), Expect = 9e-05 Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 16/109 (14%) Query: 96 AKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTK-------KPKATPVKKAKK 148 A S E + K+ K + +P+K A K+P K + K+ P K+ + Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568 Query: 149 KLAA-------TPKKAKKPKTVKAK-PVKASKPKKAK-PVKPKAKSSAK 188 K A +P+KAK P +AK P +A P+KAK PVK +AKS A+ Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617 Score = 42.7 bits (99), Expect = 2e-04 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 24/114 (21%) Query: 99 DEPKKSV--AFKKTKKEIKKVATPKKAS----------KPKK---AASKAPTKKPKATPV 143 ++PK+S A K+ ++ KKV TP+K + KPK+ A K P P Sbjct: 883 EKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS 942 Query: 144 KKAKKKLAATPK------KAKKPK---TVKAKPVKASKPKKAKPVKPKAKSSAK 188 K A+KK AA K KAKKP+ +AK + K +P KPKA+ + K Sbjct: 943 KPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996 Score = 39.7 bits (91), Expect = 0.002 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 15/116 (12%) Query: 89 ASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAA----------SKAPTKKP 138 A + + +PK+ K + + K P K ++ K+AA +K P +KP Sbjct: 910 APAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKP 969 Query: 139 KATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK 194 K KAK+ K+ KPK KA+ ++ K +KP + K++ +A K K Sbjct: 970 KTE--AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE---KATEDKAAKGK 1020 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 56.6 bits (135), Expect = 1e-08 Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 24/181 (13%) Query: 10 AAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIK 69 AAK K K K K + EK + +++ + IK K + ++K Sbjct: 632 AAKEKTVKKETKVKPEDKKEEK-------EKPKKEVAKKEDKTPIKKEEKPKKE---EVK 681 Query: 70 LSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKA 129 +K+ + K+ K + K + P K V K+ KKE KK K+ +PKK Sbjct: 682 KEVKKEIKKEEKKEPK--------KEVKKETPPKEVK-KEVKKEEKK-EVKKEEKEPKKE 731 Query: 130 ASKAPTK-KPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPK---KAKPVKPKAKS 185 K P K +TP+ +AKK A PK KK ++VK V A KPK K K +K + K+ Sbjct: 732 IKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKA 791 Query: 186 S 186 + Sbjct: 792 A 792 Score = 53.9 bits (128), Expect = 8e-08 Identities = 59/199 (29%), Positives = 81/199 (40%), Gaps = 36/199 (18%) Query: 12 KPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLS 71 KP + S + P VA QA + ++++ K +K KV + K Sbjct: 599 KPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKE---KTVKKETKVKPEDKKEEKEK 655 Query: 72 IKRLVT-----TGVLKQTKGVGASGSFRLAKSDEPKKSVAF-------KKTKKEIKKVAT 119 K+ V T + K+ K K +E KK V K+ KKE+KK Sbjct: 656 PKKEVAKKEDKTPIKKEEK----------PKKEEVKKEVKKEIKKEEKKEPKKEVKKETP 705 Query: 120 PKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPV 179 PK+ K K K KK + P K+ KK PK AKK T ++ A KP KP Sbjct: 706 PKEVKKEVKKEEKKEVKKEEKEPKKEIKK----LPKDAKKSSTPLSE---AKKPAALKPK 758 Query: 180 KPKAKSSAKR----AGKKK 194 PK + S K+ AGK K Sbjct: 759 VPKKEESVKKDSVAAGKPK 777 Score = 46.6 bits (109), Expect = 1e-05 Identities = 44/136 (32%), Positives = 56/136 (41%), Gaps = 18/136 (13%) Query: 76 VTTGVLKQTK---GVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASK 132 V T V+KQTK + S + A P KSV K++K+E +V KP K SK Sbjct: 525 VPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVR-KESKEETPEVTKVNHVEKPPKVESK 583 Query: 133 APTKKPKATPVKKAKK----------KLAATPKKA----KKPKTVKAKPVKASKPKKAKP 178 K P+K K K +P KA K+ VK K K KK Sbjct: 584 EKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETK 643 Query: 179 VKPKAKSSAKRAGKKK 194 VKP+ K K KK+ Sbjct: 644 VKPEDKKEEKEKPKKE 659 Score = 43.1 bits (100), Expect = 1e-04 Identities = 50/190 (26%), Positives = 75/190 (39%), Gaps = 26/190 (13%) Query: 27 KYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQ--IKLSIKRLVTTGVLKQT 84 K+ D + + +K+ G + K K + + ADS+ +K + K L + V K++ Sbjct: 506 KHLDFLKQPLATQKDLTGQVPTPVVKQTK----LKQRADSRESLKPAAKPLPSKSVRKES 561 Query: 85 KG----VGASGSFRLAKSDEPKKSVAFKK-------TKKEIKKVATPKKAS----KPKKA 129 K V E K+ V KK TK + + P K K + A Sbjct: 562 KEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVA 621 Query: 130 ASKAPTKKPKATPVKKAKKKLAATPK-----KAKKPKTVKAKPVKASKPKKAKPVKPKAK 184 +A KPKA K KK+ P+ K K K V K K K+ KP K + K Sbjct: 622 EKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVK 681 Query: 185 SSAKRAGKKK 194 K+ KK+ Sbjct: 682 KEVKKEIKKE 691 Score = 40.4 bits (93), Expect = 0.001 Identities = 36/131 (27%), Positives = 55/131 (41%), Gaps = 14/131 (10%) Query: 60 VGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVA-------FKKTKK 112 + +N +K +K T + G S + KSD K +A K++ Sbjct: 2227 IEQNLGKALKKDLKEKTKT----KKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSD 2282 Query: 113 EIKKVATPKKASKPKKAASKAPTKKPKAT--PVKKAKKKLAATPKKAKKPKTVKAKPVKA 170 ++ +VA+PKK +KAA T + KA K + K AA +K KT A P Sbjct: 2283 KVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGP-GT 2341 Query: 171 SKPKKAKPVKP 181 +K K+ V P Sbjct: 2342 TKTTKSSAVPP 2352 >gi|24475863 H1 histone family, member O, oocyte-specific [Homo sapiens] Length = 346 Score = 55.1 bits (131), Expect = 4e-08 Identities = 44/177 (24%), Positives = 80/177 (45%), Gaps = 20/177 (11%) Query: 25 HPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLK-- 82 HP M++ A+QA + R G+S +I+ YI Y + + K +K+ + TG+ + Sbjct: 52 HPPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVL--RFKYLLKQALATGMRRGL 109 Query: 83 -----QTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKK 137 +K GA+GSF+L + K +++ P++A + K K P++ Sbjct: 110 LARPLNSKARGATGSFKLVPKHKKKIQ------PRKMAPATAPRRAGEAKGKGPKKPSEA 163 Query: 138 PKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK 194 + P KK A P K +KP P + +KA+ AK + ++G+ + Sbjct: 164 KEDPPNVGKVKKAAKRPAKVQKP-----PPKPGAATEKARKQGGAAKDTRAQSGEAR 215 Score = 41.6 bits (96), Expect = 4e-04 Identities = 56/205 (27%), Positives = 82/205 (40%), Gaps = 37/205 (18%) Query: 8 APAAKPKRA---------KASKKSTDHPKYSDMIVAA-----IQAEKNRAGSSRQSIQKY 53 APA P+RA K S+ D P + AA +Q + G++ + +K Sbjct: 141 APATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARK- 199 Query: 54 IKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSF-RLAKSDEPKKSV----AFK 108 + G D++ + R V K + ++G R AK+ + S A++ Sbjct: 200 -----QGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYR 254 Query: 109 KTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPV 168 KTK E K+SKP ASK K A+P KK A PK + P T A P Sbjct: 255 KTKAE-------SKSSKP--TASKV--KNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPA 303 Query: 169 KASKPKKAKPVKPKAKSSAKRAGKK 193 K S K P K+ A + +K Sbjct: 304 KGS-GSKVVPAHLSRKTEAPKGPRK 327 >gi|56676330 HP1-BP74 [Homo sapiens] Length = 553 Score = 54.3 bits (129), Expect = 6e-08 Identities = 46/169 (27%), Positives = 83/169 (49%), Gaps = 13/169 (7%) Query: 32 IVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQ---IKLSIKRLVTTGVLKQTKGVG 88 I++AI A S +++KY+ ++ G N++ Q +K ++++ G ++Q G G Sbjct: 346 ILSAIAAMNEPKTCSTTALKKYVLENHP-GTNSNYQMHLLKKTLQKCEKNGWMEQISGKG 404 Query: 89 ASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKK 148 SG+F+L P V F K K+ + + + +S+ ++ + P ++ +K Sbjct: 405 FSGTFQLCFPYYPSPGVLFPK-----KEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQK 459 Query: 149 KLAA-TPKKAKKPKTVKAKP---VKASKPKKAKPVKPKAKSSAKRAGKK 193 K A +P KA K +KP V A++ KA+P+ KA AK KK Sbjct: 460 KTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKK 508 Score = 50.8 bits (120), Expect = 7e-07 Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 27/183 (14%) Query: 16 AKASKK----STDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGE--NADSQIK 69 A+A K+ S+ PK ++ AI+A ++G+S +I+KYI Y E +K Sbjct: 145 ARAQKQTPMASSPRPKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLK 204 Query: 70 LSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKA 129 ++KR + GV+KQ KG GASGSF V +K++K TP+K+ K Sbjct: 205 QALKRELNRGVIKQVKGKGASGSF-----------VVVQKSRK------TPQKSRNRKNR 247 Query: 130 ASKA-PTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPK-AKSSA 187 +S P + K V PK+A ++ K V PK ++P+ K++ Sbjct: 248 SSAVDPEPQVKLEDVLPLAFTRLCEPKEAS--YSLIRKYVSQYYPKLRVDIRPQLLKNAL 305 Query: 188 KRA 190 +RA Sbjct: 306 QRA 308 Score = 39.3 bits (90), Expect = 0.002 Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 4/104 (3%) Query: 1 MTENSTSAPAAKPKRAKASKKSTDHP--KYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHY 58 + + S P R S P K D++ A +S I+KY+ +Y Sbjct: 230 VVQKSRKTPQKSRNRKNRSSAVDPEPQVKLEDVLPLAFTRLCEPKEASYSLIRKYVSQYY 289 Query: 59 -KVGENADSQI-KLSIKRLVTTGVLKQTKGVGASGSFRLAKSDE 100 K+ + Q+ K +++R V G L+Q G GASG+F+L KS E Sbjct: 290 PKLRVDIRPQLLKNALQRAVERGQLEQITGKGASGTFQLKKSGE 333 Score = 28.9 bits (63), Expect = 2.9 Identities = 30/129 (23%), Positives = 57/129 (44%), Gaps = 3/129 (2%) Query: 59 KVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSD-EPKKSVAFKKTKKEIKKV 117 K+GE + + I+R V + K A G + D ++SV+ + ++ Sbjct: 29 KLGEKVEDST-MPIRRTVNSTRETPPKSKLAEGEEEKPEPDISSEESVSTVEEQENETPP 87 Query: 118 ATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKA-KPVKASKPKKA 176 AT +A +PK ++ K++ K +K + K+ K KT+ + + AS+ +A Sbjct: 88 ATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKKTIPSWATLSASQLARA 147 Query: 177 KPVKPKAKS 185 + P A S Sbjct: 148 QKQTPMASS 156 Score = 28.9 bits (63), Expect = 2.9 Identities = 27/128 (21%), Positives = 47/128 (36%), Gaps = 1/128 (0%) Query: 40 KNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSD 99 K SR + +S + E+ + K +++ + V GS K Sbjct: 425 KKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRGSKPAPKVS 484 Query: 100 EPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPK-KAK 158 ++ A KK K TP K ++P K P+ P A+K++ K K+ Sbjct: 485 AAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKKPSGGSSKKPATSARKEVKLPGKGKST 544 Query: 159 KPKTVKAK 166 K+ + K Sbjct: 545 MKKSFRVK 552 >gi|111548666 SNF2 histone linker PHD RING helicase isoform a [Homo sapiens] Length = 1687 Score = 52.4 bits (124), Expect = 2e-07 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 20 KKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENAD-SQIKLSIKRLVTT 78 K+ P MI+ A++ + G S SI KY+ S Y+ + S +K +K L+ Sbjct: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFE 493 Query: 79 GVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPT 135 G++KQ KG G SG+F L K+ K+ KTKK+ V +P+K K + + T Sbjct: 494 GLVKQIKGHGFSGTFTLGKN--YKEEDICDKTKKQ--AVGSPRKIQKETRKSGNKDT 546 >gi|27436873 SNF2 histone linker PHD RING helicase isoform b [Homo sapiens] Length = 1659 Score = 52.4 bits (124), Expect = 2e-07 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 5/117 (4%) Query: 20 KKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENAD-SQIKLSIKRLVTT 78 K+ P MI+ A++ + G S SI KY+ S Y+ + S +K +K L+ Sbjct: 434 KEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFE 493 Query: 79 GVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPT 135 G++KQ KG G SG+F L K+ K+ KTKK+ V +P+K K + + T Sbjct: 494 GLVKQIKGHGFSGTFTLGKN--YKEEDICDKTKKQ--AVGSPRKIQKETRKSGNKDT 546 >gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo sapiens] Length = 1158 Score = 48.5 bits (114), Expect = 4e-06 Identities = 36/104 (34%), Positives = 46/104 (44%), Gaps = 10/104 (9%) Query: 82 KQTKGVGASGSFRLAKSDE----PKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKK 137 ++TK G G K D+ PK+S+ + K PK KPK+ KA TKK Sbjct: 88 EKTKDKGKKG-----KKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKA-TKK 141 Query: 138 PKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKP 181 PK P K KK PK KKP + K P+ A P+ P Sbjct: 142 PKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPP 185 Score = 41.2 bits (95), Expect = 6e-04 Identities = 34/88 (38%), Positives = 42/88 (47%), Gaps = 14/88 (15%) Query: 108 KKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKP 167 +KTK + KK K PK++ +P P KK K+K PK KKP K KP Sbjct: 88 EKTKDKGKKGKKDKGPKVPKESLEGSPR------PPKKGKEK---PPKATKKP---KEKP 135 Query: 168 VKASKPKKAKPVK--PKAKSSAKRAGKK 193 KA+K K KP K K K +A KK Sbjct: 136 PKATKKPKEKPPKATKKPKEKPPKATKK 163 Score = 38.9 bits (89), Expect = 0.003 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 7/87 (8%) Query: 114 IKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKA-----KKPKTVKAKPV 168 ++K K K A++ P +K K K K K PK++ + PK K KP Sbjct: 66 VRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPP 125 Query: 169 KASKPKKAKPVK--PKAKSSAKRAGKK 193 KA+K K KP K K K +A KK Sbjct: 126 KATKKPKEKPPKATKKPKEKPPKATKK 152 Score = 37.0 bits (84), Expect = 0.011 Identities = 33/96 (34%), Positives = 41/96 (42%), Gaps = 20/96 (20%) Query: 101 PKKSVAFKKTKKEIKKVATPKKASK-----PKKAASKAP--TKKPKATPVKKAKKKLAAT 153 P+K+ K K+ K PK++ + PKK K P TKKPK P K AT Sbjct: 87 PEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPK-------AT 139 Query: 154 PKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKR 189 K +KP P KPK+ P K S KR Sbjct: 140 KKPKEKP------PKATKKPKEKPPKATKKPPSGKR 169 >gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sapiens] Length = 2715 Score = 47.0 bits (110), Expect = 1e-05 Identities = 43/121 (35%), Positives = 57/121 (47%), Gaps = 18/121 (14%) Query: 78 TGVLKQTKGV---GASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAAS-KA 133 TGV K+ K G+ + +K EPK K K+E K+ P+KA +PKKA K Sbjct: 90 TGVKKKRKKKEPGDQEGAAKGSKDREPKP-----KRKREPKEPKEPRKAKEPKKAKEHKE 144 Query: 134 PTKKPKATPVKKAKKKLAATPKKAKKPK------TVKAKPVKASKPKKAKPVKPKAKSSA 187 P +K A KKA+K A+ K K K + K KASK + PV+ K K Sbjct: 145 PKQKDGA---KKARKPREASGTKEAKEKRSCTDSAARTKSRKASKEQGPTPVEKKKKGKR 201 Query: 188 K 188 K Sbjct: 202 K 202 Score = 40.0 bits (92), Expect = 0.001 Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 2/81 (2%) Query: 114 IKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKP 173 +KK K+ + AA + ++PK P +K + K P+KAK+PK K K Sbjct: 92 VKKKRKKKEPGDQEGAAKGSKDREPK--PKRKREPKEPKEPRKAKEPKKAKEHKEPKQKD 149 Query: 174 KKAKPVKPKAKSSAKRAGKKK 194 K KP+ S K A +K+ Sbjct: 150 GAKKARKPREASGTKEAKEKR 170 Score = 36.2 bits (82), Expect = 0.018 Identities = 27/91 (29%), Positives = 41/91 (45%), Gaps = 8/91 (8%) Query: 111 KKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVK------ 164 KK+ KK + K + + P K K P + + + A PKKAK+ K K Sbjct: 93 KKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKAKEPKKAKEHKEPKQKDGAK 152 Query: 165 --AKPVKASKPKKAKPVKPKAKSSAKRAGKK 193 KP +AS K+AK + S+A+ +K Sbjct: 153 KARKPREASGTKEAKEKRSCTDSAARTKSRK 183 >gi|4557509 cylicin 2 [Homo sapiens] Length = 348 Score = 45.8 bits (107), Expect = 2e-05 Identities = 59/194 (30%), Positives = 77/194 (39%), Gaps = 24/194 (12%) Query: 2 TENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVG 61 TE+ AK K K KK ++ K S A ++E + G+ + S K K K G Sbjct: 176 TESEDEKGGAK-KDNKKDKKDSNKGKDS-----ATESEGEKGGTEKDS--KKGKKDSKKG 227 Query: 62 ENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPK 121 + DS I+L +K + G K DE K + KK KEIKK K Sbjct: 228 K--DSAIELQ--------AVKADEKKDEDGKKDANKGDESKDA---KKDAKEIKKGKKDK 274 Query: 122 KASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKA-KPVK 180 K + SK KK K KK+A K +K K K + K A K K Sbjct: 275 KKPSSTDSDSKDDVKKESKKDATKDAKKVA--KKDTEKESADSKKDAKKNAKKDAKKDAK 332 Query: 181 PKAKSSAKRAGKKK 194 AK K+ KKK Sbjct: 333 KNAKKDEKKDAKKK 346 >gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sapiens] Length = 2997 Score = 45.8 bits (107), Expect = 2e-05 Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 3/89 (3%) Query: 98 SDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKA 157 S E KK K KK+ K+ PK+ +PK+ + K PK KKAK ATPK Sbjct: 637 SQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAK---TATPKPK 693 Query: 158 KKPKTVKAKPVKASKPKKAKPVKPKAKSS 186 K+ KP + K K K K + S Sbjct: 694 SSKKSSNKKPDSEASALKKKVNKGKTEGS 722 Score = 42.0 bits (97), Expect = 3e-04 Identities = 28/73 (38%), Positives = 37/73 (50%), Gaps = 9/73 (12%) Query: 121 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVK 180 ++ K K++ +K K+PK P +K + K TPK K P K K KKAK Sbjct: 639 EEKKKKKRSKAKKDPKEPKE-PKEKKEPKEPKTPKAPKIP--------KEPKEKKAKTAT 689 Query: 181 PKAKSSAKRAGKK 193 PK KSS K + KK Sbjct: 690 PKPKSSKKSSNKK 702 Score = 40.4 bits (93), Expect = 0.001 Identities = 31/87 (35%), Positives = 36/87 (41%), Gaps = 14/87 (16%) Query: 108 KKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKP 167 KK KK K PK+ +PK+ K PKA PK K+PK KAK Sbjct: 641 KKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKA-------------PKIPKEPKEKKAK- 686 Query: 168 VKASKPKKAKPVKPKAKSSAKRAGKKK 194 KPK +K K S A KKK Sbjct: 687 TATPKPKSSKKSSNKKPDSEASALKKK 713 Score = 37.4 bits (85), Expect = 0.008 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 6/72 (8%) Query: 96 AKSD--EPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPV---KKAKKKL 150 AK D EPK+ KK KE K PK +PK+ +K T KPK++ KK + Sbjct: 649 AKKDPKEPKEPKE-KKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEA 707 Query: 151 AATPKKAKKPKT 162 +A KK K KT Sbjct: 708 SALKKKVNKGKT 719 >gi|11067749 bromodomain containing protein 3 [Homo sapiens] Length = 726 Score = 45.8 bits (107), Expect = 2e-05 Identities = 34/111 (30%), Positives = 49/111 (44%), Gaps = 5/111 (4%) Query: 84 TKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPV 143 +KG +S S + SD ++ + + K + A S+AP KPK Sbjct: 434 SKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPVNKPKKKKE 493 Query: 144 KKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK 194 KK K+K KK K K + VKA + KKAK P ++ K+A KK Sbjct: 494 KKEKEK-----KKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKK 539 Score = 33.9 bits (76), Expect = 0.089 Identities = 32/100 (32%), Positives = 43/100 (43%), Gaps = 9/100 (9%) Query: 94 RLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAAT 153 RLA+ E K+V + V PKK K K KK K +K K K+ A Sbjct: 462 RLAELQEQLKAVHEQLAALSQAPVNKPKK-----KKEKKEKEKKKKDKEKEKEKHKVKAE 516 Query: 154 PKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKK 193 +K K A P K ++ KKA K + ++A R KK Sbjct: 517 EEK----KAKVAPPAKQAQQKKAPAKKANSTTTAGRQLKK 552 Score = 32.7 bits (73), Expect = 0.20 Identities = 40/192 (20%), Positives = 68/192 (35%), Gaps = 9/192 (4%) Query: 3 ENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGE 62 E A A P + +A +K K + A Q +K +S + + + Sbjct: 516 EEEKKAKVAPPAK-QAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSY 574 Query: 63 NADSQIKLSIKRL-------VTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIK 115 + Q+ L I RL V + + + S + E K ++ ++ +K Sbjct: 575 DEKRQLSLDINRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVK 634 Query: 116 KVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKK 175 KK KP A+ K K K ++ KK+L + + KP + KP Sbjct: 635 S-CLQKKQRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGS 693 Query: 176 AKPVKPKAKSSA 187 A P SS+ Sbjct: 694 APSGGPSRLSSS 705 Score = 30.8 bits (68), Expect = 0.76 Identities = 24/71 (33%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 97 KSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKP--KATPVKKAKKKLAATP 154 K + KK KK KE +K KA + KKA P K+ K P KKA A Sbjct: 489 KKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTTTAGR 548 Query: 155 KKAKKPKTVKA 165 + K K A Sbjct: 549 QLKKGGKQASA 559 >gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sapiens] Length = 699 Score = 45.4 bits (106), Expect = 3e-05 Identities = 60/212 (28%), Positives = 87/212 (41%), Gaps = 26/212 (12%) Query: 7 SAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSR------QSIQKYIKSHYKV 60 + P AK + KAS ++ + V A+K + R ++ K +S Sbjct: 71 NGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSE 130 Query: 61 GENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKS----------DEPKKSVAFKKT 110 + D + K+ V GV Q K A + AKS DEP K+ K T Sbjct: 131 ESSDDDDEEDQKKQPVQKGVKPQAKAAKAPP--KKAKSSDSDSDSSSEDEPPKNQKPKIT 188 Query: 111 KKEIKKV--ATPKKA-SKPK----KAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTV 163 +K A PK A + PK KAAS + + ++ ++K AATPKK K V Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV 248 Query: 164 KAK-PVKASKPKKAKPVKPKAKSSAKRAGKKK 194 AK PVKA+ K + SS + +KK Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEEEEQKK 280 Score = 44.3 bits (103), Expect = 7e-05 Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 17/197 (8%) Query: 10 AAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENA--DSQ 67 AAK + +S++S+D D +Q + ++ K KS +++ D Sbjct: 120 AAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEP 179 Query: 68 IKLSIKRLVTTGVLKQTKG-------VGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATP 120 K ++ V QTK + + A S S + +E K ATP Sbjct: 180 PKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATP 239 Query: 121 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAK--------PVKASK 172 KK K+ +KAP K K + + +++ ++ ++ K +K K P A Sbjct: 240 KKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPP 299 Query: 173 PKKAKPVKPKAKSSAKR 189 PKK+ +P K+ K+ Sbjct: 300 PKKSLGTQPPKKAVEKQ 316 Score = 39.7 bits (91), Expect = 0.002 Identities = 55/211 (26%), Positives = 83/211 (39%), Gaps = 34/211 (16%) Query: 8 APAAKPKRAKASKKSTDH-----------PKYSDMIV------------AAIQAEKNRAG 44 A A PK+AK+S +D PK + + V AA + +A Sbjct: 156 AAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAA 215 Query: 45 SSRQSIQKYIKSHYKVGENADSQIKLSI--KRLVTTGVLKQ-TKGVGASGSFRLAKSDEP 101 SS S S E A + K ++ K++V +K T S S + SDE Sbjct: 216 SSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEE 275 Query: 102 KKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKP--KATPVKKAKK---KLAATPKK 156 ++ K K P A PKK+ P KK K PV+ ++ + ++ ++ Sbjct: 276 EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE 335 Query: 157 AKKPKTVKAKPVKASKPKKAKPVKPKAKSSA 187 KKP T K V + K P K A+SS+ Sbjct: 336 EKKPPT---KAVVSKATTKPPPAKKAAESSS 363 Score = 34.7 bits (78), Expect = 0.052 Identities = 39/178 (21%), Positives = 72/178 (40%), Gaps = 5/178 (2%) Query: 4 NSTSAPAAKPKRAKASKKSTDHPKYSDM--IVAAIQAEKNRAGSSRQSIQKYIKSHYKVG 61 +S+ A K A +K S++ P + V A K G ++ + + S Sbjct: 369 DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEE 428 Query: 62 ENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPK 121 E++ S+ + + K++V T K T S + A S + E ++ T K Sbjct: 429 ESSSSEEEKT-KKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSK 487 Query: 122 KA--SKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAK 177 A KP+K A A KP + KA+ +++ + + + K K + +P+ K Sbjct: 488 SAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPK 545 Score = 30.8 bits (68), Expect = 0.76 Identities = 44/199 (22%), Positives = 70/199 (35%), Gaps = 16/199 (8%) Query: 3 ENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGE 62 E S+S+ K K+ A+ K PK + ++ A++ GS R S S + E Sbjct: 428 EESSSSEEEKTKKMVATTK----PKATAKAALSLPAKQAPQGS-RDSSSDSDSSSSEEEE 482 Query: 63 NADSQIKLSIKRLVTTGVLKQTKGV----GASGSFRLAKSDEPKKSVAFKKTKKEIKKVA 118 S+ + K G +K G + S + SD+ + K K + Sbjct: 483 EKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQ 542 Query: 119 TPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKP 178 PK A K ++ KK K K + + K ++ +AK Sbjct: 543 APKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK 602 Query: 179 VK-------PKAKSSAKRA 190 +K PK K KRA Sbjct: 603 IKLQTPNTFPKRKKGEKRA 621 Score = 29.6 bits (65), Expect = 1.7 Identities = 29/149 (19%), Positives = 55/149 (36%), Gaps = 5/149 (3%) Query: 42 RAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEP 101 +A +Q ++ S + +++ + K K +V+ K A+ S S + Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAES-----SSDS 365 Query: 102 KKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPK 161 S + + + K T K +S +K+P KP A P + +KA Sbjct: 366 SDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSS 425 Query: 162 TVKAKPVKASKPKKAKPVKPKAKSSAKRA 190 + + + K K K++AK A Sbjct: 426 SEEESSSSEEEKTKKMVATTKPKATAKAA 454 Score = 28.9 bits (63), Expect = 2.9 Identities = 26/109 (23%), Positives = 40/109 (36%), Gaps = 10/109 (9%) Query: 96 AKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPT-------KKPKATPVKKAKK 148 + S+E KK K K KKA++ +S + + KP T + K Sbjct: 331 SSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390 Query: 149 KLAATPKKAKKPKTVKAKPVKASK---PKKAKPVKPKAKSSAKRAGKKK 194 T A KP +PV + +KA + +SS+ K K Sbjct: 391 PAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTK 439 >gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] Length = 248 Score = 44.7 bits (104), Expect = 5e-05 Identities = 34/110 (30%), Positives = 44/110 (40%), Gaps = 3/110 (2%) Query: 85 KGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVK 144 KGV + + + K KKT K+ KK T K K K TK K T Sbjct: 6 KGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRT--- 62 Query: 145 KAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK 194 KK T K K+ + K K + K K+ + K K K K+ KKK Sbjct: 63 TTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKK 112 Score = 44.3 bits (103), Expect = 7e-05 Identities = 34/98 (34%), Positives = 45/98 (45%), Gaps = 5/98 (5%) Query: 94 RLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAAT 153 R K+ + KK KKT + KK T KK + K TKK T K+ +K+ Sbjct: 27 RKKKTTKKKKK---KKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKE 83 Query: 154 PKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAG 191 +K K+ + K K K K KK K K K K +AK G Sbjct: 84 KEKEKEKEKEKEKEKKKKKKKKKK--KKKKKLNAKVCG 119 Score = 28.9 bits (63), Expect = 2.9 Identities = 22/80 (27%), Positives = 32/80 (40%) Query: 73 KRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASK 132 K+ TT K+ + + K K TK++ K+ K+ K K+ + Sbjct: 36 KKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKE 95 Query: 133 APTKKPKATPVKKAKKKLAA 152 KK K KK KKKL A Sbjct: 96 KEKKKKKKKKKKKKKKKLNA 115 >gi|125656165 THO complex 2 [Homo sapiens] Length = 1593 Score = 43.9 bits (102), Expect = 9e-05 Identities = 37/151 (24%), Positives = 66/151 (43%), Gaps = 4/151 (2%) Query: 44 GSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKK 103 GS+ +S + + K E + +K K TT + G S S + K ++ +K Sbjct: 1214 GSASKSDESSTEETDKSRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEK 1273 Query: 104 SVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTV 163 +K KKE TP+ K K ++P +KA++ TPK K+ + Sbjct: 1274 GKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKD--EKARETKERTPKSDKEKE-- 1329 Query: 164 KAKPVKASKPKKAKPVKPKAKSSAKRAGKKK 194 K K + +K +K K P A+S + + +++ Sbjct: 1330 KFKKEEKAKDEKFKTTVPNAESKSTQERERE 1360 >gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens] Length = 490 Score = 43.1 bits (100), Expect = 1e-04 Identities = 44/152 (28%), Positives = 65/152 (42%), Gaps = 15/152 (9%) Query: 12 KPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLS 71 K R KA K+T+ + D I + K + + IQK+ ++ + Sbjct: 347 KRGRGKAQVKATNESE--DEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRG 404 Query: 72 IKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFK-KTKKEIKKVATPKKASKPKKAA 130 KR K + AS + + A+S+ P KS K K K+E K +P K + Sbjct: 405 KKR----------KALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQT 454 Query: 131 SKAPTKKPKATPVKKAKKKLAATPKK-AKKPK 161 K P K TP K+ +K + TPKK KKPK Sbjct: 455 PKKPEAKFFTTP-SKSVRKASHTPKKWPKKPK 485 Score = 38.1 bits (87), Expect = 0.005 Identities = 39/105 (37%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Query: 89 ASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASK--PKKAASKAPTKKPKATPVKK- 145 A+G AKS P S K +K + TPK A P K+ K P K +A K Sbjct: 387 ATGKKSPAKSPNP--STPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSP 444 Query: 146 --AKKKLAATPKKAK-KPKTVKAKPV-KASKPKKAKPVKPKAKSS 186 KK TPKK + K T +K V KAS K P KPK S Sbjct: 445 SLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQS 489 Score = 35.8 bits (81), Expect = 0.023 Identities = 47/193 (24%), Positives = 75/193 (38%), Gaps = 34/193 (17%) Query: 12 KPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLS 71 K K A+ ++ + K + QA K + S+ + E+ D+ +K Sbjct: 283 KKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAP---------ESGDTTVKKP 333 Query: 72 IKRLVTT---GVLKQTKGVGASGSFRLAKSDEPKKSVAFKKT----KKEIKKVATPKKA- 123 + T G K+ +G + ++ + P+ KKT K EI+K AT KK+ Sbjct: 334 ESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSP 393 Query: 124 ----------SKPKKA--ASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKAS 171 K +KA AS+ P TP K +KK K K+ + P Sbjct: 394 AKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKK-----PKIKEEAVKEKSPSLGK 448 Query: 172 KPKKAKPVKPKAK 184 K + P KP+AK Sbjct: 449 KDARQTPKKPEAK 461 >gi|153791662 coiled-coil domain containing 71 [Homo sapiens] Length = 467 Score = 42.4 bits (98), Expect = 3e-04 Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 9/118 (7%) Query: 81 LKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVA-TPKKASKPKKAASKAPTK--- 136 +++ KG A G+ K+ + K + K + KVA T KA+K + A A K Sbjct: 267 VRRMKGGSALGT----KTAQAKVARTLAKAARAQAKVARTQAKAAKARAKAKAAQVKAKA 322 Query: 137 KPKATPVKKAKKKLAATPKKAKKPKTVKAK-PVKASKPKKAKPVKPKAKSSAKRAGKK 193 K KA VK K +AA K K K V+AK V ++P+ K AK+ R G+K Sbjct: 323 KAKAAQVKAKAKVMAAWAKAKAKAKAVRAKAKVARTQPRGRGRPKGSAKARTTRKGQK 380 Score = 35.0 bits (79), Expect = 0.040 Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 12/118 (10%) Query: 84 TKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPK-KAASKAPTKKPKATP 142 TK A + LAK+ + VA +T+ + K KA++ K KA +KA K KA Sbjct: 278 TKTAQAKVARTLAKAARAQAKVA--RTQAKAAKARAKAKAAQVKAKAKAKAAQVKAKAKV 335 Query: 143 VK---KAKKKLAATPKKAKKPKTVKAKPVKASKPK---KAKPVKPKAKSSAKRAGKKK 194 + KAK K A KAK +T +P +PK KA+ + K+ + G+K+ Sbjct: 336 MAAWAKAKAKAKAVRAKAKVART---QPRGRGRPKGSAKARTTRKGQKNRPETVGQKR 390 >gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 [Homo sapiens] Length = 559 Score = 42.0 bits (97), Expect = 3e-04 Identities = 50/202 (24%), Positives = 73/202 (36%), Gaps = 29/202 (14%) Query: 19 SKKSTDHPKYSDMIVAAIQAEK-----------NRAGSSRQSIQKYIKSHYKVGENADSQ 67 S+ S D+P + ++A K N+ S K K H + DS+ Sbjct: 152 SRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEH-RERPRKDSE 210 Query: 68 IKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDE-PKKSVAFKKTKKEIK---------KV 117 K S K L G RL K ++ P AFK+ K +K K Sbjct: 211 SKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKG 270 Query: 118 ATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKA---KKPKTVKAKPVKASKPK 174 P P +A+SK P P K +KK ++ ++ P+T + KP Sbjct: 271 GPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPA 330 Query: 175 KAKP----VKPKAKSSAKRAGK 192 K K K KA+S + A K Sbjct: 331 KDKSSTRGEKVKAESEPREAKK 352 >gi|11225260 DNA topoisomerase I [Homo sapiens] Length = 765 Score = 41.6 bits (96), Expect = 4e-04 Identities = 47/176 (26%), Positives = 74/176 (42%), Gaps = 16/176 (9%) Query: 12 KPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLS 71 K K + SK S K S+ + K++ GSS + K+ ++ D + + Sbjct: 40 KEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKH--------KDRDKEKRKE 91 Query: 72 IK-RLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKAS----KP 126 K R +K+ K G S ++ DEP+ F K++IK + P+ KP Sbjct: 92 EKVRASGDAKIKKEKENGFSSPPQI--KDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKP 149 Query: 127 KKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPK 182 KK ++ TKK K +++ + PK K K V K KPKK + K K Sbjct: 150 KKIKTE-DTKKEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKWK 204 >gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] Length = 1379 Score = 41.2 bits (95), Expect = 6e-04 Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 26/206 (12%) Query: 9 PAAKPKRAKASKKSTD---HPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHY-KVGENA 64 P+AK + AS++S+ HP ++ + A + S KS+ K G Sbjct: 789 PSAKSRILIASQRSSASAIHPPGPITTATSLYSSDPSADLKKASSSNAAKSNLPKSGLRP 848 Query: 65 DSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEP-------------------KKSV 105 +L +L G ++ + V + S + S +P K S+ Sbjct: 849 PGYSRLPAAKLAAFGFVRSSS-VSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASL 907 Query: 106 AFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKA 165 K T K +VA P +S S P K +TP KK A + KP Sbjct: 908 PSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPA--GTKKDAQKDQDTNKPAVSSP 965 Query: 166 KPVKASKPKKAKPVKPKAKSSAKRAG 191 K V AS K P PK +++A R G Sbjct: 966 KRVAASTTKLHSPGYPKQRTAAARNG 991 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 40.8 bits (94), Expect = 7e-04 Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 12/144 (8%) Query: 47 RQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGAS---GSFRLAKSDEPKK 103 ++ +K + S K E D IK ++ V K+ G + G+ ++A KK Sbjct: 316 KKKAEKKVTSETKKKEKED--IKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKK 373 Query: 104 SVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTV 163 + K++ KK P + +PK K K+ P K KK+ + K K KT Sbjct: 374 D----EKKEDSKKTKKPAEVEQPK--GKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTE 427 Query: 164 KAK-PVKASKPKKAKPVKPKAKSS 186 +AK + A KKA P K + K++ Sbjct: 428 RAKEEIGAVSIKKAVPGKKEEKTT 451 Score = 38.9 bits (89), Expect = 0.003 Identities = 32/129 (24%), Positives = 54/129 (41%), Gaps = 9/129 (6%) Query: 62 ENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPK 121 E + + K + K++ + K+ + + A E K+ +TK+ K+A Sbjct: 310 EEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQA 369 Query: 122 KASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKP 181 A K +K TKKP K K K+ KK K V +P K+ K + + P Sbjct: 370 AAKKDEKKEDSKKTKKPAEVEQPKGK-------KQEKKEKHV--EPAKSPKKEHSVPSDK 420 Query: 182 KAKSSAKRA 190 + K+ +RA Sbjct: 421 QVKAKTERA 429 Score = 38.9 bits (89), Expect = 0.003 Identities = 60/212 (28%), Positives = 86/212 (40%), Gaps = 37/212 (17%) Query: 16 AKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYI--KSHYKVGENADSQIKLSIK 73 AK+ KK +H SD V A + E+ + SI+K + K K + + +I+ K Sbjct: 407 AKSPKK--EHSVPSDKQVKA-KTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKE-K 462 Query: 74 RLVTTGVLKQTKGVGASGSFRLA----KSDEPKKSVAFKKTKKEIKKVATP---KKASKP 126 T+ +LK + + A K E KK K KE+K KK KP Sbjct: 463 SGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKP 522 Query: 127 ----KKAASKAPTKK----------PKAT-----PVKKAKKKL-AATPKKAKKPKTVKAK 166 KK A A ++K P+ T P +K K++ A T +K KPK K Sbjct: 523 EPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKA 582 Query: 167 PVKASKPKKAKPVK----PKAKSSAKRAGKKK 194 + +P K K PK S +GKKK Sbjct: 583 EHREREPPSIKTDKPKPTPKGTSEVTESGKKK 614 Score = 38.5 bits (88), Expect = 0.004 Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 19/115 (16%) Query: 99 DEP---KKSVAFKKTKKE------IKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKK 149 DEP KK + KT+K+ I+ T K+ K K+ + + KAT +K +KK Sbjct: 134 DEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKK 193 Query: 150 -------LAATPKKAK---KPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK 194 LA KKAK K + K VK K +K K K K K K K Sbjct: 194 EKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPK 248 Score = 35.0 bits (79), Expect = 0.040 Identities = 30/114 (26%), Positives = 51/114 (44%), Gaps = 6/114 (5%) Query: 73 KRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKK--TKKEIKKVATPKKASKPKKAA 130 +R + T V + K G ++ + ++P+K K+ KKE + T K K K A Sbjct: 155 ERKIQTKVTHKEK---EKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTA 211 Query: 131 SKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAK 184 K+ K K K ++K+ T K K+ + +KP + +KA K + K Sbjct: 212 EKSEEKTKKEVKGGK-QEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQK 264 Score = 33.9 bits (76), Expect = 0.089 Identities = 30/105 (28%), Positives = 45/105 (42%), Gaps = 5/105 (4%) Query: 95 LAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKP-KATPVKKAKKKLAA- 152 L + + KK K T + KK K K+ A K+P KA+ K+ K+AA Sbjct: 309 LEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQ 368 Query: 153 --TPKKAKKPKTVKAK-PVKASKPKKAKPVKPKAKSSAKRAGKKK 194 K KK + K K P + +PK K K + ++ KK+ Sbjct: 369 AAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKE 413 Score = 32.3 bits (72), Expect = 0.26 Identities = 31/128 (24%), Positives = 48/128 (37%), Gaps = 20/128 (15%) Query: 80 VLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPK 139 VLKQ K V + K+ +PK + + ++E + T K P K S+ K Sbjct: 561 VLKQVKAV------TIEKTAKPKPTKKAEHREREPPSIKTDKPKPTP-KGTSEVTESGKK 613 Query: 140 ATPVKKAKKKLAATPKKAKKPK-------------TVKAKPVKASKPKKAKPVKPKAKSS 186 T + + + K A K ++ K T KP + SK + P KAK Sbjct: 614 KTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEG 673 Query: 187 AKRAGKKK 194 + K Sbjct: 674 TEDVSPTK 681 Score = 31.6 bits (70), Expect = 0.44 Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 16/86 (18%) Query: 121 KKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPK------------TVKAKPV 168 ++AS+P A+ P + K KKA+KK+ + KK +K K +P Sbjct: 297 EQASRPTPAS---PALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353 Query: 169 KASKPKKAKPVKPKAKSSAKRAGKKK 194 KAS+ K+ VK A+++AK+ KK+ Sbjct: 354 KASETKQGT-VKIAAQAAAKKDEKKE 378 >gi|109637759 calpastatin isoform f [Homo sapiens] Length = 750 Score = 40.4 bits (93), Expect = 0.001 Identities = 50/206 (24%), Positives = 84/206 (40%), Gaps = 39/206 (18%) Query: 8 APAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQ 67 A + +P+RA A++++ +H + ++ G + S +K S +G + S Sbjct: 9 AASPRPRRAAAARRTHEH------VSEKTSESPSKPGEKKGSDEKKAAS---LGSSQSS- 58 Query: 68 IKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFK----KTKKEIKKVATPKKA 123 R G TK +SG+ + S P ++ A K K + K + PK+A Sbjct: 59 ------RTYAGGTASATKVSASSGATSKSSSMNPTETKAVKTEPEKKSQSTKPKSLPKQA 112 Query: 124 SKP-------KKAASKAPTKKP--KAT-PVKKAKKKLAATPKKAKKPKTVKAKPVKASKP 173 S KKA S++ ++P K+T P K + ++A + + KP K Sbjct: 113 SDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKE 172 Query: 174 KK---------AKPVKPKAKSSAKRA 190 KK +KP KP KS A Sbjct: 173 KKSLTPAVPVESKPDKPSGKSGMDAA 198 >gi|56118310 nuclear casein kinase and cyclin-dependent kinase substrate 1 [Homo sapiens] Length = 243 Score = 40.4 bits (93), Expect = 0.001 Identities = 35/111 (31%), Positives = 45/111 (40%), Gaps = 14/111 (12%) Query: 83 QTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKAT- 141 Q K G+ F + D+ + KK KK +KK SKP++ K P + KAT Sbjct: 126 QEKDSGSDEDFLMEDDDDSDYGSSKKKNKKMVKK-------SKPERKEKKMPKPRLKATV 178 Query: 142 ---PVKKAKKKLAATPKKAKKPKTVKAK---PVKASKPKKAKPVKPKAKSS 186 PVK K T KA K KT K S P+K P + S Sbjct: 179 TPSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPPEKKTSTSPPPEKS 229 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.301 0.115 0.297 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,490,630 Number of Sequences: 37866 Number of extensions: 267155 Number of successful extensions: 4990 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 243 Number of HSP's successfully gapped in prelim test: 351 Number of HSP's that attempted gapping in prelim test: 2176 Number of HSP's gapped (non-prelim): 1948 length of query: 194 length of database: 18,247,518 effective HSP length: 97 effective length of query: 97 effective length of database: 14,574,516 effective search space: 1413728052 effective search space used: 1413728052 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.