Guide to the Human Genome
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Search of human proteins with 4759162

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759162 SRY-box 14 [Homo sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759162 SRY-box 14 [Homo sapiens]                                  500   e-142
gi|5902108 SRY-box 21 [Homo sapiens]                                  290   1e-78
gi|28195386 sex-determining region Y-box 2 [Homo sapiens]             177   9e-45
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]       176   2e-44
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]       165   3e-41
gi|5902106 SRY-box 15 [Homo sapiens]                                  140   1e-33
gi|11967991 SRY-box 17 [Homo sapiens]                                 124   7e-29
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]      123   2e-28
gi|4507161 SRY-box 11 [Homo sapiens]                                  122   2e-28
gi|4507225 sex determining region Y [Homo sapiens]                    122   4e-28
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]        121   5e-28
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]       120   8e-28
gi|4557853 transcription factor SOX9 [Homo sapiens]                   120   8e-28
gi|8924248 SRY-box 18 [Homo sapiens]                                  120   1e-27
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]       120   1e-27
gi|13899269 SRY-box 7 [Homo sapiens]                                  116   2e-26
gi|41406089 SRY-box 13 [Homo sapiens]                                 107   7e-24
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo...   105   5e-23
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo...   105   5e-23
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo...   105   5e-23
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom...   100   9e-22
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom...   100   9e-22
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo...   100   9e-22
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo...   100   9e-22
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom...    99   3e-21
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo...    92   4e-19
gi|112421108 capicua homolog [Homo sapiens]                            71   7e-13
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa...    61   8e-10
gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo sap...    61   8e-10
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]    59   3e-09

>gi|4759162 SRY-box 14 [Homo sapiens]
          Length = 240

 Score =  500 bits (1287), Expect = e-142
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE 60
           MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE
Sbjct: 1   MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE 60

Query: 61  AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLS 120
           AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLS
Sbjct: 61  AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLS 120

Query: 121 APEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSL 180
           APEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSL
Sbjct: 121 APEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAFGSL 180

Query: 181 SCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM 240
           SCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM
Sbjct: 181 SCPSQHTHTHPSPTNPGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM 240


>gi|5902108 SRY-box 21 [Homo sapiens]
          Length = 276

 Score =  290 bits (741), Expect = 1e-78
 Identities = 162/285 (56%), Positives = 190/285 (66%), Gaps = 54/285 (18%)

Query: 1   MSKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDE 60
           MSKP DH+KRPMNAFMVWSR QRRKMAQENPKMHNSEISKRLGAEWKLL+E+EKRP+IDE
Sbjct: 1   MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDE 60

Query: 61  AKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPY-LG-----DTDPLKA-AGLPVG 113
           AKRLRA HMKEHPDYKYRPRRKPK LLKKD++ FP+PY LG     +   LKA AGL  G
Sbjct: 61  AKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPALKAGAGLHAG 120

Query: 114 ASDG-----LLSAPEK---------ARAFLPPASA-------------PYSLLDPAQFSS 146
           A  G     LL+ PEK         AR F P ++A             PYSLLD      
Sbjct: 121 AGGGLVPESLLANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSLLDLG---- 176

Query: 147 SAIQKMGEVPHTLATGALPYASTLGYQN---GAF--------GSLSCPSQHTHTHPSPTN 195
               KM E+  + ++  LPYAS+LGY     GAF         + +    HTH+HPSP N
Sbjct: 177 ---SKMAEI--SSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGN 231

Query: 196 PGYVVPCNCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM 240
           PGY++PCNC+AW +  LQPP+AYIL PGM K  +DPY +A+A A+
Sbjct: 232 PGYMIPCNCSAWPSPGLQPPLAYILLPGMGKPQLDPYPAAYAAAL 276


>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
          Length = 317

 Score =  177 bits (448), Expect = 9e-45
 Identities = 86/112 (76%), Positives = 92/112 (82%)

Query: 6   DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLR 65
           D +KRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSE EKRP+IDEAKRLR
Sbjct: 39  DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLR 98

Query: 66  AQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDG 117
           A HMKEHPDYKYRPRRK K L+KKD+Y  P   L       A+G+ VGA  G
Sbjct: 99  ALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLG 150


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score =  176 bits (446), Expect = 2e-44
 Identities = 101/193 (52%), Positives = 119/193 (61%), Gaps = 10/193 (5%)

Query: 6   DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLR 65
           D +KRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWK++SEAEKRP+IDEAKRLR
Sbjct: 49  DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLR 108

Query: 66  AQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKA 125
           A HMKEHPDYKYRPRRK K LLKKD+Y      L        A + +G   G+ +A    
Sbjct: 109 ALHMKEHPDYKYRPRRKTKTLLKKDKYSLAGGLLAAGAGGGGAAVAMGVGVGVGAAAVGQ 168

Query: 126 RAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGY--QNGAFGSLSCP 183
           R   P  +A         +++ A    G V    A  A+   + L Y    GA G+    
Sbjct: 169 RLESPGGAAGGGYAHVNGWANGAYP--GSVAAAAAAAAMMQEAQLAYGQHPGAGGA---- 222

Query: 184 SQHTHTHPSPTNP 196
             H H HP+  +P
Sbjct: 223 --HPHAHPAHPHP 233


>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
          Length = 446

 Score =  165 bits (418), Expect = 3e-41
 Identities = 84/126 (66%), Positives = 94/126 (74%), Gaps = 11/126 (8%)

Query: 6   DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLR 65
           D +KRPMNAFMVWSRGQRRKMA ENPKMHNSEISKRLGA+WKLL++AEKRP+IDEAKRLR
Sbjct: 137 DRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRLR 196

Query: 66  AQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAPEKA 125
           A HMKE+PDYKYRPRRK K LLKKD+Y  P           +  LP GA+    +A   A
Sbjct: 197 AVHMKEYPDYKYRPRRKTKTLLKKDKYSLP-----------SGLLPPGAAAAAAAAAAAA 245

Query: 126 RAFLPP 131
            A   P
Sbjct: 246 AAASSP 251


>gi|5902106 SRY-box 15 [Homo sapiens]
          Length = 233

 Score =  140 bits (352), Expect = 1e-33
 Identities = 61/82 (74%), Positives = 75/82 (91%)

Query: 4   PSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKR 63
           P + +KRPMNAFMVWS  QRR+MAQ+NPKMHNSEISKRLGA+WKLL E EKRP+++EAKR
Sbjct: 45  PLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKR 104

Query: 64  LRAQHMKEHPDYKYRPRRKPKN 85
           LRA+H++++PDYKYRPRRK K+
Sbjct: 105 LRARHLRDYPDYKYRPRRKAKS 126


>gi|11967991 SRY-box 17 [Homo sapiens]
          Length = 414

 Score =  124 bits (311), Expect = 7e-29
 Identities = 66/139 (47%), Positives = 94/139 (67%), Gaps = 6/139 (4%)

Query: 2   SKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEA 61
           +K    I+RPMNAFMVW++ +R+++AQ+NP +HN+E+SK LG  WK L+ AEKRP+++EA
Sbjct: 62  AKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEA 121

Query: 62  KRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVG---ASDGL 118
           +RLR QHM++HP+YKYRPRR+ +  +K+ + V      G  +P  AA  P G   A DGL
Sbjct: 122 ERLRVQHMQDHPNYKYRPRRRKQ--VKRLKRVEGGFLHGLAEPQAAALGPEGGRVAMDGL 179

Query: 119 -LSAPEKARAFLPPASAPY 136
            L  PE+     PP   P+
Sbjct: 180 GLQFPEQGFPAGPPLLPPH 198


>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
          Length = 315

 Score =  123 bits (308), Expect = 2e-28
 Identities = 66/131 (50%), Positives = 85/131 (64%), Gaps = 14/131 (10%)

Query: 4   PSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKR 63
           PS HIKRPMNAFMVWS+ +RRK+  + P MHN+EISKRLG  W+LL ++EK P++ EA+R
Sbjct: 36  PSGHIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAER 95

Query: 64  LRAQHMKEHPDYKYRPRRKPKNLLKKDR-----------YVFPLPYLGDTDPLKAAGLPV 112
           LR +HM ++PDYKYRPR+K K    K R            + P P L      +AAG P+
Sbjct: 96  LRLKHMADYPDYKYRPRKKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPL 155

Query: 113 GASDGLLSAPE 123
           G   G  +APE
Sbjct: 156 G---GGAAAPE 163


>gi|4507161 SRY-box 11 [Homo sapiens]
          Length = 441

 Score =  122 bits (307), Expect = 2e-28
 Identities = 53/80 (66%), Positives = 69/80 (86%)

Query: 5   SDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRL 64
           S HIKRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WK+L ++EK P+I EA+RL
Sbjct: 46  SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERL 105

Query: 65  RAQHMKEHPDYKYRPRRKPK 84
           R +HM ++PDYKYRPR+KPK
Sbjct: 106 RLKHMADYPDYKYRPRKKPK 125


>gi|4507225 sex determining region Y [Homo sapiens]
          Length = 204

 Score =  122 bits (305), Expect = 4e-28
 Identities = 55/83 (66%), Positives = 70/83 (84%)

Query: 6   DHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLR 65
           D +KRPMNAF+VWSR QRRKMA ENP+M NSEISK+LG +WK+L+EAEK P+  EA++L+
Sbjct: 58  DRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQ 117

Query: 66  AQHMKEHPDYKYRPRRKPKNLLK 88
           A H +++P+YKYRPRRK K L K
Sbjct: 118 AMHREKYPNYKYRPRRKAKMLPK 140


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score =  121 bits (304), Expect = 5e-28
 Identities = 53/82 (64%), Positives = 70/82 (85%)

Query: 4   PSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKR 63
           PS HIKRPMNAFMVWS+ +RRK+ +++P MHN+EISKRLG  WKLL +++K P+I EA+R
Sbjct: 55  PSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAER 114

Query: 64  LRAQHMKEHPDYKYRPRRKPKN 85
           LR +HM ++PDYKYRPR+K K+
Sbjct: 115 LRLKHMADYPDYKYRPRKKVKS 136


>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
          Length = 446

 Score =  120 bits (302), Expect = 8e-28
 Identities = 50/80 (62%), Positives = 67/80 (83%)

Query: 3   KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAK 62
           K   H+KRPMNAFMVW++  RRK+A + P +HN+E+SK LG  W+LLSE+EKRP+++EA+
Sbjct: 97  KAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAE 156

Query: 63  RLRAQHMKEHPDYKYRPRRK 82
           RLR QH K+HPDYKY+PRR+
Sbjct: 157 RLRVQHKKDHPDYKYQPRRR 176


>gi|4557853 transcription factor SOX9 [Homo sapiens]
          Length = 509

 Score =  120 bits (302), Expect = 8e-28
 Identities = 50/81 (61%), Positives = 68/81 (83%)

Query: 2   SKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEA 61
           SK   H+KRPMNAFMVW++  RRK+A + P +HN+E+SK LG  W+LL+E+EKRP+++EA
Sbjct: 99  SKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEA 158

Query: 62  KRLRAQHMKEHPDYKYRPRRK 82
           +RLR QH K+HPDYKY+PRR+
Sbjct: 159 ERLRVQHKKDHPDYKYQPRRR 179


>gi|8924248 SRY-box 18 [Homo sapiens]
          Length = 384

 Score =  120 bits (301), Expect = 1e-27
 Identities = 70/155 (45%), Positives = 98/155 (63%), Gaps = 29/155 (18%)

Query: 8   IKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQ 67
           I+RPMNAFMVW++ +R+++AQ+NP +HN+ +SK LG  WK L+ AEKRP+++EA+RLR Q
Sbjct: 85  IRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQ 144

Query: 68  HMKEHPDYKYRPRRKPKNLLKKDRYVFP---LPYLG----DTDPLKAAG---------LP 111
           H+++HP+YKYRPRRK +   +K R + P   LP L       +P  AA           P
Sbjct: 145 HLRDHPNYKYRPRRKKQ--ARKARRLEPGLLLPGLAPPQPPPEPFPAASGSARAFRELPP 202

Query: 112 VGAS-DGL-LSAPEKA---------RAFLPPASAP 135
           +GA  DGL L  PE++          AF PP +AP
Sbjct: 203 LGAEFDGLGLPTPERSPLDGLEPGEAAFFPPPAAP 237


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score =  120 bits (300), Expect = 1e-27
 Identities = 50/81 (61%), Positives = 68/81 (83%)

Query: 2   SKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEA 61
           SK   H+KRPMNAFMVW++  RRK+A + P +HN+E+SK LG  W+LL+E++KRP+I+EA
Sbjct: 98  SKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEA 157

Query: 62  KRLRAQHMKEHPDYKYRPRRK 82
           +RLR QH K+HPDYKY+PRR+
Sbjct: 158 ERLRMQHKKDHPDYKYQPRRR 178


>gi|13899269 SRY-box 7 [Homo sapiens]
          Length = 388

 Score =  116 bits (291), Expect = 2e-26
 Identities = 77/203 (37%), Positives = 105/203 (51%), Gaps = 19/203 (9%)

Query: 8   IKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQ 67
           I+RPMNAFMVW++ +R+++A +NP +HN+E+SK LG  WK L+ ++KRPY+DEA+RLR Q
Sbjct: 45  IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQ 104

Query: 68  HMKEHPDYKYRPRRK--PKNLLKKDRYVFPLPYLG---DTDPLKAAGLPVGASDGLLSAP 122
           HM+++P+YKYRPRRK   K L K+    F L  L    +  P K +G     S G L   
Sbjct: 105 HMQDYPNYKYRPRRKKQAKRLCKRVDPGFLLSSLSRDQNALPEKRSG-----SRGALGEK 159

Query: 123 EKARAFLPPASAP-----YSLLDPAQFSSSAIQKMGEVPHTLATGALPYASTLGYQNGAF 177
           E    + P  + P     Y               +   P+ L T   P  S L       
Sbjct: 160 EDRGEYSPGTALPSLRGCYHEGPAGGGGGGTPSSVDTYPYGLPTP--PEMSPLDVLEPEQ 217

Query: 178 GSLSCPSQHTHTHPS--PTNPGY 198
              S P Q  H HP   P  PG+
Sbjct: 218 TFFSSPCQEEHGHPRRIPHLPGH 240


>gi|41406089 SRY-box 13 [Homo sapiens]
          Length = 622

 Score =  107 bits (268), Expect = 7e-24
 Identities = 47/81 (58%), Positives = 62/81 (76%)

Query: 2   SKPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEA 61
           S+ S HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+PY +E 
Sbjct: 418 SRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQ 477

Query: 62  KRLRAQHMKEHPDYKYRPRRK 82
            RL  QH++++PDYKY+PR K
Sbjct: 478 ARLSRQHLEKYPDYKYKPRPK 498


>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
           sapiens]
          Length = 377

 Score =  105 bits (261), Expect = 5e-23
 Identities = 45/76 (59%), Positives = 59/76 (77%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+PY +E  RL  
Sbjct: 169 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 228

Query: 67  QHMKEHPDYKYRPRRK 82
           QH++++PDYKY+PR K
Sbjct: 229 QHLEKYPDYKYKPRPK 244


>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
           sapiens]
          Length = 750

 Score =  105 bits (261), Expect = 5e-23
 Identities = 45/76 (59%), Positives = 59/76 (77%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+PY +E  RL  
Sbjct: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601

Query: 67  QHMKEHPDYKYRPRRK 82
           QH++++PDYKY+PR K
Sbjct: 602 QHLEKYPDYKYKPRPK 617


>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
           sapiens]
          Length = 763

 Score =  105 bits (261), Expect = 5e-23
 Identities = 45/76 (59%), Positives = 59/76 (77%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK ++  EK+PY +E  RL  
Sbjct: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614

Query: 67  QHMKEHPDYKYRPRRK 82
           QH++++PDYKY+PR K
Sbjct: 615 QHLEKYPDYKYKPRPK 630


>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
           sapiens]
          Length = 841

 Score =  100 bits (250), Expect = 9e-22
 Identities = 44/76 (57%), Positives = 58/76 (76%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +S  EK+PY +E  RL  
Sbjct: 633 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 692

Query: 67  QHMKEHPDYKYRPRRK 82
            H++++P+YKY+PR K
Sbjct: 693 IHLEKYPNYKYKPRPK 708


>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
           sapiens]
          Length = 801

 Score =  100 bits (250), Expect = 9e-22
 Identities = 44/76 (57%), Positives = 58/76 (76%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +S  EK+PY +E  RL  
Sbjct: 593 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 652

Query: 67  QHMKEHPDYKYRPRRK 82
            H++++P+YKY+PR K
Sbjct: 653 IHLEKYPNYKYKPRPK 668


>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
           sapiens]
          Length = 804

 Score =  100 bits (250), Expect = 9e-22
 Identities = 44/76 (57%), Positives = 58/76 (76%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +S  EK+PY +E  RL  
Sbjct: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655

Query: 67  QHMKEHPDYKYRPRRK 82
            H++++P+YKY+PR K
Sbjct: 656 IHLEKYPNYKYKPRPK 671


>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
           sapiens]
          Length = 808

 Score =  100 bits (250), Expect = 9e-22
 Identities = 44/76 (57%), Positives = 58/76 (76%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           HIKRPMNAFMVW++ +RRK+ Q  P MHNS ISK LG+ WK +S  EK+PY +E  RL  
Sbjct: 600 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 659

Query: 67  QHMKEHPDYKYRPRRK 82
            H++++P+YKY+PR K
Sbjct: 660 IHLEKYPNYKYKPRPK 675


>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
           sapiens]
          Length = 753

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 76/239 (31%), Positives = 109/239 (45%), Gaps = 33/239 (13%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           H+KRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  LSE +K+PY DEA++++ 
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395

Query: 67  QHMKEHPDYKYRPR-RKPKNLLKKDRYVFP--------------LPYLGDTDPLKAAGL- 110
           +H +E P + Y+PR  K K        VF                PY   T  +    L 
Sbjct: 396 KHREEFPGWVYQPRPGKRKRFPLSVSNVFSGTTQNIISTNPTTVYPYRSPTYSVVIPSLQ 455

Query: 111 -----PVGASDGLLSAPEKARAFLPPASAPYSLLDPAQFSSSAIQKMGEVPHTLATGALP 165
                PVG +   +  P  A      + +P +L  P+   SSA Q   + P      ALP
Sbjct: 456 NPITHPVGETSPAIQLPTPA----VQSPSPVTLFQPS--VSSAAQVAVQDPSLPVYPALP 509

Query: 166 YASTLGYQNGAFGSLSCPSQHTHTHPSPTNPGYVVPCNCTA------WSASTLQPPVAY 218
                G        L   + HT   P+P +       + +A      ++ ST+QPP  Y
Sbjct: 510 PQRFTGPSQTDTHQLHSEATHTVKQPTPVSLESANRISSSASTAHARFATSTIQPPREY 568


>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
           sapiens]
          Length = 501

 Score = 92.0 bits (227), Expect = 4e-19
 Identities = 39/74 (52%), Positives = 56/74 (75%)

Query: 7   HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
           H+KRPMNAFMVW+R  R  +A+ NP  +N+EIS +LG EW  LSE +K+PY DEA++++ 
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395

Query: 67  QHMKEHPDYKYRPR 80
           +H +E P + Y+PR
Sbjct: 396 KHREEFPGWVYQPR 409


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 33/83 (39%), Positives = 50/83 (60%)

Query: 3   KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAK 62
           +  DHI+RPMNAFM++S+  R  + Q +P   N  +SK LG  W  L   EK+ Y D A 
Sbjct: 195 REKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAF 254

Query: 63  RLRAQHMKEHPDYKYRPRRKPKN 85
           +++  H K HPD+K+  + + K+
Sbjct: 255 QVKEAHFKAHPDWKWCNKDRKKS 277


>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
           sapiens]
          Length = 941

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 51/160 (31%), Positives = 73/160 (45%), Gaps = 16/160 (10%)

Query: 4   PSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKR 63
           P    +RPMNAF+++ +  R  + QE+P++ N   +K L   W +L   EK+ Y D AK 
Sbjct: 76  PEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKE 135

Query: 64  LRAQHMKEHPDYKYRP-RRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAP 122
            +   MK +P YK+ P   KP           P P +     L A   P  +S  L S P
Sbjct: 136 YKDAFMKANPGYKWCPTTNKPVK--------SPTPTVNPRKKLWA--FPSDSSRDLPS-P 184

Query: 123 EKARAFLPPASAPYSLLDPAQFSS-SAIQKMGEVPHTLAT 161
           +KA+    P    + + DP Q    S +   GE  H L T
Sbjct: 185 KKAKTEEMP-QLNFGMADPTQMGGLSMLLLAGE--HALGT 221


>gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo
           sapiens]
          Length = 911

 Score = 61.2 bits (147), Expect = 8e-10
 Identities = 51/160 (31%), Positives = 73/160 (45%), Gaps = 16/160 (10%)

Query: 4   PSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKR 63
           P    +RPMNAF+++ +  R  + QE+P++ N   +K L   W +L   EK+ Y D AK 
Sbjct: 76  PEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKE 135

Query: 64  LRAQHMKEHPDYKYRP-RRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAP 122
            +   MK +P YK+ P   KP           P P +     L A   P  +S  L S P
Sbjct: 136 YKDAFMKANPGYKWCPTTNKPVK--------SPTPTVNPRKKLWA--FPSDSSRDLPS-P 184

Query: 123 EKARAFLPPASAPYSLLDPAQFSS-SAIQKMGEVPHTLAT 161
           +KA+    P    + + DP Q    S +   GE  H L T
Sbjct: 185 KKAKTEEMP-QLNFGMADPTQMGGLSMLLLAGE--HALGT 221


>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
          Length = 579

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 38/125 (30%), Positives = 60/125 (48%), Gaps = 20/125 (16%)

Query: 3   KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAK 62
           K   HIK+P+NAFM++ +  R K+  E     ++ I++ LG  W  LS  E+  Y + A+
Sbjct: 322 KKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELAR 381

Query: 63  RLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAP 122
           + R  HM+ +P +  R     K   K+D+        G+T+               LSAP
Sbjct: 382 KERQLHMQLYPGWSARDNYGKKKKRKRDKQP------GETND--------------LSAP 421

Query: 123 EKARA 127
           +K RA
Sbjct: 422 KKCRA 426


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,627,050
Number of Sequences: 37866
Number of extensions: 512006
Number of successful extensions: 1873
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 1693
Number of HSP's gapped (non-prelim): 253
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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