Search of human proteins with 4758280

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758280 ephrin receptor EphA4 [Homo sapiens]
         (986 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758280 ephrin receptor EphA4 [Homo sapiens]                      2007   0.0  
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...  1319   0.0  
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...  1305   0.0  
gi|4758282 ephrin receptor EphA7 [Homo sapiens]                      1302   0.0  
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi...  1285   0.0  
gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                1218   0.0  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...  1171   0.0  
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...  1170   0.0  
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...  1168   0.0  
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]            1164   0.0  
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]           1130   0.0  
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                      971   0.0  
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                  961   0.0  
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]                 896   0.0  
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                     796   0.0  
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]           783   0.0  
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi...   683   0.0  
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi...   537   e-152
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]                320   5e-87
gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]     231   2e-60
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]       227   5e-59
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]              224   4e-58
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...   223   5e-58
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...   223   5e-58
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]      223   5e-58
gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]   220   6e-57
gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]   220   6e-57
gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...   219   1e-56
gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...   219   1e-56
gi|112789548 lymphocyte-specific protein tyrosine kinase precurs...   219   1e-56

>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
          Length = 986

 Score = 2007 bits (5200), Expect = 0.0
 Identities = 986/986 (100%), Positives = 986/986 (100%)

Query: 1   MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM 60
           MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM
Sbjct: 1   MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM 60

Query: 61  DEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE 120
           DEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE
Sbjct: 61  DEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE 120

Query: 121 TFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG 180
           TFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG
Sbjct: 121 TFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG 180

Query: 181 FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK 240
           FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK
Sbjct: 181 FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK 240

Query: 241 DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSV 300
           DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSV
Sbjct: 241 DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSV 300

Query: 301 WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI 360
           WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI
Sbjct: 301 WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI 360

Query: 361 SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVS 420
           SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVS
Sbjct: 361 SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVS 420

Query: 421 KYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE 480
           KYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE
Sbjct: 421 KYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE 480

Query: 481 KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII 540
           KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII
Sbjct: 481 KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII 540

Query: 541 GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF 600
           GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF
Sbjct: 541 GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF 600

Query: 601 TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT 660
           TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT
Sbjct: 601 TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT 660

Query: 661 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV 720
           DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV
Sbjct: 661 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV 720

Query: 721 IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT 780
           IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT
Sbjct: 721 IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT 780

Query: 781 TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG 840
           TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG
Sbjct: 781 TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG 840

Query: 841 YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNT 900
           YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNT
Sbjct: 841 YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNT 900

Query: 901 ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAIT 960
           ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAIT
Sbjct: 901 ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAIT 960

Query: 961 HQNKILSSVQAMRTQMQQMHGRMVPV 986
           HQNKILSSVQAMRTQMQQMHGRMVPV
Sbjct: 961 HQNKILSSVQAMRTQMQQMHGRMVPV 986


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 1319 bits (3413), Expect = 0.0
 Identities = 646/975 (66%), Positives = 774/975 (79%), Gaps = 13/975 (1%)

Query: 9    LFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIR 68
            L++CL  +C A+      P+NEV LLDSR+V G+LGWIA P + GWEE+  +DE   PI 
Sbjct: 40   LWTCLL-LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDENYAPIH 97

Query: 69   TYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYE 128
            TYQVC VME +QNNWL T WI+ EGA R++IE+KFTLRDCNSLPG +GTCKETFN+YY+E
Sbjct: 98   TYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFE 157

Query: 129  SDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDV 188
            SD+   R I+ENQ++KIDTIAADESFT++D+GDR+MKLNTE+RDVGPLSKKGFYLAFQDV
Sbjct: 158  SDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDV 217

Query: 189  GACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCG 248
            GACIALVSVRV+YKKCP  VR+LA FPDTITGAD+S L+EV GSCVN+S   + PKM+C 
Sbjct: 218  GACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCS 277

Query: 249  ADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCT 308
            A+GEWLVPIG C+C AG+EE++G CQ C+ G++KA     +C KCPPHSY+  E +TSC 
Sbjct: 278  AEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCV 337

Query: 309  CDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKK 368
            C++ +FR ++D  +M CTRPPSAP N ISNVNETSV LEW  P +TGGR+D+SY + CKK
Sbjct: 338  CEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKK 397

Query: 369  CGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQ 428
            C +     C  CG  V Y P+Q+GLK T V + DLLAHTNYTFEI AVNGVS  +P   Q
Sbjct: 398  CNS-HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQ 456

Query: 429  SVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSY 488
             VSV VTTNQAAPS +  V+  ++ + S++L+W EPDRPNG+ILEYE+KY+EKDQ E SY
Sbjct: 457  YVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSY 515

Query: 489  RIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTV 548
             I+++       +GL P + YVF +RARTAAGYG FS   E  T  V +    D +   V
Sbjct: 516  TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAAS-SDQSQIPV 574

Query: 549  LLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEK------HLN-QGVRTYVDPFT 601
            + VSV+  V+L+ ++I   ++S RR  YSKAKQ+ +EEK      H+   GVRTY+DP T
Sbjct: 575  IAVSVTVGVILLAVVIGV-LLSGRRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHT 633

Query: 602  YEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTD 661
            YEDPNQAV EFAKEI+ASCI IE+VIG GEFGEVCSGRLK+PGKRE+ VAIKTLK GYT+
Sbjct: 634  YEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTE 693

Query: 662  KQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI 721
            KQRRDFL EASIMGQFDHPNIIHLEGVVTK KPVMI+TEYMENGSLD FL+KNDG+FTVI
Sbjct: 694  KQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVI 753

Query: 722  QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT 781
            QLVGMLRGI +GMKYLSDM YVHRDLAARNIL+NSNLVCKVSDFG+SRVLEDDPEAAYTT
Sbjct: 754  QLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTT 813

Query: 782  RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 841
            RGGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SYGERPYW+M+NQDVIKA+EEGY
Sbjct: 814  RGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGY 873

Query: 842  RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTA 901
            RLP PMDCP AL+QLMLDCWQKER+ RPKF +IVNMLDKLIRNP+SLK     S R +  
Sbjct: 874  RLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNL 933

Query: 902  LLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITH 961
            L + S     A  SVG+WL+AIKM RY + F   GY++++AV  V  EDL R+G+T + H
Sbjct: 934  LAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGH 993

Query: 962  QNKILSSVQAMRTQM 976
            Q KI++S+Q M+ Q+
Sbjct: 994  QKKIMNSLQEMKVQL 1008


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 1305 bits (3378), Expect = 0.0
 Identities = 644/996 (64%), Positives = 771/996 (77%), Gaps = 33/996 (3%)

Query: 9    LFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIR 68
            L++CL  +C A+      P+NEV LLDSR+V G+LGWIA P + GWEE+  +DE   PI 
Sbjct: 40   LWTCLL-LCAALRTLLASPSNEVNLLDSRTVMGDLGWIAFP-KNGWEEIGEVDENYAPIH 97

Query: 69   TYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYE 128
            TYQVC VME +QNNWL T WI+ EGA R++IE+KFTLRDCNSLPG +GTCKETFN+YY+E
Sbjct: 98   TYQVCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFE 157

Query: 129  SDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDV 188
            SD+   R I+ENQ++KIDTIAADESFT++D+GDR+MKLNTE+RDVGPLSKKGFYLAFQDV
Sbjct: 158  SDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDV 217

Query: 189  GACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCG 248
            GACIALVSVRV+YKKCP  VR+LA FPDTITGAD+S L+EV GSCVN+S   + PKM+C 
Sbjct: 218  GACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCS 277

Query: 249  ADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCT 308
            A+GEWLVPIG C+C AG+EE++G CQ C+ G++KA     +C KCPPHSY+  E +TSC 
Sbjct: 278  AEGEWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCV 337

Query: 309  CDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKK 368
            C++ +FR ++D  +M CTRPPSAP N ISNVNETSV LEW  P +TGGR+D+SY + CKK
Sbjct: 338  CEKDYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKK 397

Query: 369  CGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQ 428
            C +     C  CG  V Y P+Q+GLK T V + DLLAHTNYTFEI AVNGVS  +P   Q
Sbjct: 398  CNS-HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQ 456

Query: 429  SVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSY 488
             VSV VTTNQAAPS +  V+  ++ + S++L+W EPDRPNG+ILEYE+KY+EKDQ E SY
Sbjct: 457  YVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEKDQ-ETSY 515

Query: 489  RIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTV 548
             I+++       +GL P + YVF +RARTAAGYG FS   E  T  V +    D +   V
Sbjct: 516  TIIKSKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTPVFAAS-SDQSQIPV 574

Query: 549  LLVSVSGSVVLVVILIAAFVISRR---------------------RSKYSKAKQEADEEK 587
            + VSV+  V+L+ ++I   +                         R  YSKAKQ+ +EEK
Sbjct: 575  IAVSVTVGVILLAVVIGVLLSGSCCECGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEK 634

Query: 588  ------HLN-QGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRL 640
                  H+   GVRTY+DP TYEDPNQAV EFAKEI+ASCI IE+VIG GEFGEVCSGRL
Sbjct: 635  MHFHNGHIKLPGVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRL 694

Query: 641  KVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITE 700
            K+PGKRE+ VAIKTLK GYT+KQRRDFL EASIMGQFDHPNIIHLEGVVTK KPVMI+TE
Sbjct: 695  KLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTE 754

Query: 701  YMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVC 760
            YMENGSLD FL+KNDG+FTVIQLVGMLRGI +GMKYLSDM YVHRDLAARNIL+NSNLVC
Sbjct: 755  YMENGSLDTFLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVC 814

Query: 761  KVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSY 820
            KVSDFG+SRVLEDDPEAAYTTRGGKIPIRWTAPEAIA+RKFTSASDVWSYGIVMWEV+SY
Sbjct: 815  KVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSY 874

Query: 821  GERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDK 880
            GERPYW+M+NQDVIKA+EEGYRLP PMDCP AL+QLMLDCWQKER+ RPKF +IVNMLDK
Sbjct: 875  GERPYWEMTNQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDK 934

Query: 881  LIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTL 940
            LIRNP+SLK     S R +  L + S     A  SVG+WL+AIKM RY + F   GY+++
Sbjct: 935  LIRNPSSLKTLVNASCRVSNLLAEHSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSM 994

Query: 941  EAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQM 976
            +AV  V  EDL R+G+T + HQ KI++S+Q M+ Q+
Sbjct: 995  DAVAQVTLEDLRRLGVTLVGHQKKIMNSLQEMKVQL 1030


>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
          Length = 998

 Score = 1302 bits (3369), Expect = 0.0
 Identities = 623/972 (64%), Positives = 775/972 (79%), Gaps = 16/972 (1%)

Query: 28  ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87
           A EV LLDS++ Q EL WI+SP   GWEE+S +DE  TPIRTYQVC VMEP+QNNWLRT+
Sbjct: 30  AKEVLLLDSKAQQTELEWISSP-PNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRTN 88

Query: 88  WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDT 147
           WI++  AQR+++E+KFTLRDCNSLPGV+GTCKETFNLYYYE+D D  R IREN +VKIDT
Sbjct: 89  WISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKIDT 148

Query: 148 IAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLT 207
           IAADESFTQ D+G+R MKLNTE+R++GPLSKKGFYLAFQDVGACIALVSV+V+YKKC   
Sbjct: 149 IAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSI 208

Query: 208 VRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK--DVPKMYCGADGEWLVPIGNCLCNAG 265
           + NLA FPDT+TG++ SSLVEVRG+CV+++EE+  + P+M+C A+GEWLVPIG C+C AG
Sbjct: 209 IENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAG 268

Query: 266 HEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPC 325
           ++++   C+ C  G+YK+ S D  C++CP HS+S  EG++ C C+ G++RA +D   + C
Sbjct: 269 YQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVAC 328

Query: 326 TRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVH 385
           TRPPSAP NLI N+N+T+V+LEWS P + GGR D++Y ++CK+C + +  +C PCGS + 
Sbjct: 329 TRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRC-SWEQGECVPCGSNIG 387

Query: 386 YTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIA 445
           Y PQQ GL+   V++ DLLAH NYTFE+ AVNGVS  + +     +V++TT QAAPS ++
Sbjct: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447

Query: 446 LVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNP 505
            V  + V + SV L+W EP+ PNGVI EYE+KYYEKDQ ER+Y  V+T + +  I  L P
Sbjct: 448 GVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKP 507

Query: 506 LTSYVFHVRARTAAGYGDFSEPLEVTT------NTVPSRIIGDGANSTVLL--VSVSGSV 557
            T YVF +RA TAAGYG++S  L+V T          +  +    N  +++  V+V+G++
Sbjct: 508 GTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTI 567

Query: 558 VLVVILIAAFVISRRRSKYSKAKQEADEEKHLN---QGVRTYVDPFTYEDPNQAVREFAK 614
           +LV  ++  F+I RR   YSKA QE DEE + +    G +TY+DP TYEDPN+AV +FAK
Sbjct: 568 ILV-FMVFGFIIGRRHCGYSKADQEGDEELYFHFKFPGTKTYIDPETYEDPNRAVHQFAK 626

Query: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674
           E+DASCIKIE+VIG GEFGEVCSGRLK+PGKR++ VAIKTLK GYT+KQRRDFL EASIM
Sbjct: 627 ELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIM 686

Query: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGM 734
           GQFDHPN++HLEGVVT+ KPVMI+ E+MENG+LDAFLRK+DG+FTVIQLVGMLRGI +GM
Sbjct: 687 GQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGM 746

Query: 735 KYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPE 794
           +YL+DM YVHRDLAARNILVNSNLVCKVSDFG+SRV+EDDPEA YTT GGKIP+RWTAPE
Sbjct: 747 RYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPE 806

Query: 795 AIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALH 854
           AI YRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLP PMDCP  LH
Sbjct: 807 AIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLH 866

Query: 855 QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVV 914
           QLMLDCWQKER++RPKF QIV +LDK+IRNPNSLK      SRP + LLD ++P+F+   
Sbjct: 867 QLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFC 926

Query: 915 SVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRT 974
           SVG+WLQAIKM+RYKDNFTAAGY +LE+V  +  ED+  +GIT + HQ KI+SS+Q MR 
Sbjct: 927 SVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRA 986

Query: 975 QMQQMHGRMVPV 986
           QM  +HG  + V
Sbjct: 987 QMLHLHGTGIQV 998


>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
           sapiens]
          Length = 983

 Score = 1285 bits (3325), Expect = 0.0
 Identities = 615/956 (64%), Positives = 763/956 (79%), Gaps = 13/956 (1%)

Query: 27  PANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRT 86
           P+NEV LLDS+++QGELGWI+ P  G WEE+S +DE  TPIRTYQVCNVM+ SQNNWLRT
Sbjct: 26  PSNEVNLLDSKTIQGELGWISYPSHG-WEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84

Query: 87  DWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKID 146
           +W+ R  AQ++Y+E+KFTLRDCNS+P V+GTCKETFNLYY ESD+D     RE+QF KID
Sbjct: 85  NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144

Query: 147 TIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPL 206
           TIAADESFTQ+D+GDRI+KLNTEIR+VGP++KKGFYLAFQDVGAC+ALVSVRV++KKCP 
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204

Query: 207 TVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGH 266
           TV+NLA FPDT+   D+ SLVEVRGSCVNNS+E+D P+MYC  +GEWLVPIG C CNAG+
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGY 263

Query: 267 EERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCT 326
           EER   CQAC+ G+YKAL  +  CAKCPPHS +  +G+ +C C+  +FRAD D  SM CT
Sbjct: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323

Query: 327 RPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHY 386
           RPPS+P N+ISN+NETSV L+WS P +TGGR+D+++N++CKKCG  +  +C PC   V +
Sbjct: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG-WNIKQCEPCSPNVRF 382

Query: 387 TPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIAL 446
            P+Q GL  T V++TDLLAHTNYTFEI AVNGVS+ +  P Q  +V++TTNQAAPS +  
Sbjct: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442

Query: 447 VQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPL 506
           ++    +R S++L+W EP+ PNG+IL+YEVKYYEK + E SY I+R    N  I  L P 
Sbjct: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502

Query: 507 TSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAA 566
           T YVF +RARTAAGYG  S   E  T+  P      G +S V+++++S +V ++++ +  
Sbjct: 503 TIYVFQIRARTAAGYGTNSRKFEFETS--PDSFSISGESSQVVMIAISAAVAIILLTVVI 560

Query: 567 FVISRRRSKYSKAKQEADEEK------HLN-QGVRTYVDPFTYEDPNQAVREFAKEIDAS 619
           +V+  R   Y K+K  ADE++      HL   G+RTYVDP TYEDP QAV EFAKE+DA+
Sbjct: 561 YVLIGRFCGY-KSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQAVHEFAKELDAT 619

Query: 620 CIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDH 679
            I I+KV+G GEFGEVCSGRLK+P K+EI VAIKTLK GYT+KQRRDFL EASIMGQFDH
Sbjct: 620 NISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDH 679

Query: 680 PNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSD 739
           PNII LEGVVTK KPVMI+TEYMENGSLD+FLRK+D +FTVIQLVGMLRGI SGMKYLSD
Sbjct: 680 PNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSD 739

Query: 740 MSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYR 799
           M YVHRDLAARNIL+NSNLVCKVSDFG+SRVLEDDPEAAYTTRGGKIPIRWT+PEAIAYR
Sbjct: 740 MGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTSPEAIAYR 799

Query: 800 KFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLD 859
           KFTSASDVWSYGIV+WEVMSYGERPYW+MSNQDVIKA++EGYRLPPPMDCP AL+QLMLD
Sbjct: 800 KFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLD 859

Query: 860 CWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDW 919
           CWQK+R++RPKF QIV++LDKLIRNP SLK   + ++RP+  LLD S+ + +   + GDW
Sbjct: 860 CWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSNLLLDQSNVDITTFRTTGDW 919

Query: 920 LQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ 975
           L  +     K+ FT   Y++ + +  ++ +D+ ++G+T +  Q KI+SS++A+ TQ
Sbjct: 920 LNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQKKIISSIKALETQ 975


>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 1218 bits (3152), Expect = 0.0
 Identities = 602/1029 (58%), Positives = 746/1029 (72%), Gaps = 68/1029 (6%)

Query: 5    FYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKN 64
            F+  L +   G C  V+       N+V LLD+ +V GELGW   PL G W+ ++ MDE N
Sbjct: 109  FFLPLLTAWPGDCSHVSN------NQVVLLDTTTVLGELGWKTYPLNG-WDAITEMDEHN 161

Query: 65   TPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNL 124
             PI TYQVCNVMEP+QNNWLRT+WI+R+ AQ++Y+E+KFTLRDCNS+P V+GTCKETFNL
Sbjct: 162  RPIHTYQVCNVMEPNQNNWLRTNWISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNL 221

Query: 125  YYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLA 184
            +Y ESD       + NQ+ KIDTIAADESFTQ+D+GDRI+KLNTEIR+VGP+ +KGFYLA
Sbjct: 222  FYMESDESHGIKFKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVGPIERKGFYLA 281

Query: 185  FQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPK 244
            FQD+GACIALVSVRVFYKKCP TVRNLA FPDTI   D+SSLVEVRGSCV ++EE+D PK
Sbjct: 282  FQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPK 341

Query: 245  MYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGA 304
            +YCGADG+WLVP+G C+C+ G+EE  G C AC+ G+YKA + +  C+KCPPHS +  E  
Sbjct: 342  LYCGADGDWLVPLGRCICSTGYEEIEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEAT 401

Query: 305  TSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNV 364
            + C C++G+FRA+ D  SM CTRPPSAP N++ N+NET++ LEWS P +TGGR+D++Y+V
Sbjct: 402  SVCQCEKGYFRAEKDPPSMACTRPPSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSV 461

Query: 365  VCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNP 424
            +CKKCG  D S+C  CG G+ + P+  GL    V + D ++H NYTFEI A+NGVS+ + 
Sbjct: 462  ICKKCGL-DTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSF 520

Query: 425  NPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQN 484
            +P    ++TVTT+Q APS I +V+    ++ S+AL+W  P   NG IL+YE+KYYEK+  
Sbjct: 521  SPKPFTAITVTTDQDAPSLIGVVRKDWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHE 580

Query: 485  ERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGA 544
            + +Y   R+ A +  I GL P T YVFH+R RTA GY  +S+  E  T    S +  +  
Sbjct: 581  QLTYSSTRSKAPSVIITGLKPATKYVFHIRVRTATGYSGYSQKFEFETGDETSDMAAEQG 640

Query: 545  NSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEK--HLNQ------GVRTY 596
               V+  +  G   L+VIL   F+I+ R   Y KAK +++E++  HL        G++TY
Sbjct: 641  QILVIATAAVGGFTLLVILTLFFLITGRCQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTY 700

Query: 597  VDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLK 656
            +DP TYEDP+ AV EFAKEID S I+IE+VIG GEFGEVCSGRLK PGKREI VAIKTLK
Sbjct: 701  IDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGKREIPVAIKTLK 760

Query: 657  AGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTK-----------C------------- 692
             G+ D+QRRDFL EASIMGQFDHPNII LEGVVTK           C             
Sbjct: 761  GGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQ 820

Query: 693  ------------------KPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGM 734
                              +PVMI+ EYMENGSLD+FLRK+DG FTVIQLVGMLRGI SGM
Sbjct: 821  APHPVPGGGSLPPRIPAGRPVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGM 880

Query: 735  KYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPE 794
            KYLSDM YVHRDLAARNILVNSNLVCKVSDFG+SRVLEDDPEAAYTT GGKIPIRWTAPE
Sbjct: 881  KYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPE 940

Query: 795  AIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALH 854
            AIAYRKF+SASD WSYGIVMWEVMSYGERPYW+MSNQDVI +IEEGYRLP PM CP +LH
Sbjct: 941  AIAYRKFSSASDAWSYGIVMWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLH 1000

Query: 855  QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSS----PEF 910
            QLML CWQKER+ RPKF  IV+ LDKLIRNP++L       +     L+ P S    PE+
Sbjct: 1001 QLMLHCWQKERNHRPKFTDIVSFLDKLIRNPSAL------HTLVEDILVMPESPGEVPEY 1054

Query: 911  SAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQ 970
               V+VGDWL +IKM +YK+NF AAG+TT + +  ++ +D+ RIG+  I HQ +I+SS+Q
Sbjct: 1055 PLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISRMSIDDIRRIGVILIGHQRRIVSSIQ 1114

Query: 971  AMRTQMQQM 979
             +R  M  +
Sbjct: 1115 TLRLHMMHI 1123


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 1171 bits (3029), Expect = 0.0
 Identities = 577/968 (59%), Positives = 726/968 (75%), Gaps = 19/968 (1%)

Query: 28  ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87
           A E TL+DS +   ELGW+  P   GWEEVS  DE    IRTYQVCNV E SQNNWLRT 
Sbjct: 18  AVEETLMDSTTATAELGWMVHP-PSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTK 76

Query: 88  WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFI----RENQFV 143
           +I R GA R+++E+KF++RDC+S+P V G+CKETFNLYYYE+D D          EN +V
Sbjct: 77  FIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWV 136

Query: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203
           K+DTIAADESF+QVD+G R+MK+NTE+R  GP+S+ GFYLAFQD G C++L++VRVFY+K
Sbjct: 137 KVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRK 196

Query: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262
           CP  ++N A F +T++GA+++SLV  RGSC+ N+EE DVP K+YC  DGEWLVPIG C+C
Sbjct: 197 CPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMC 256

Query: 263 NAGHE--ERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDA 320
            AG E  E    C+ C  G +KA   D  C  CP +S +  EGAT+C C  G++RAD D 
Sbjct: 257 KAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDP 316

Query: 321 ASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPC 380
             MPCT  PSAP  +IS+VNETS+ LEW+ P+++GGR+D+ YN++CK CG+G  + C  C
Sbjct: 317 LDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGA-CTRC 375

Query: 381 GSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAA 440
           G  V Y P+Q GL   ++ I+DLLAHT YTFEI AVNGV+  +P   Q  SV +TTNQAA
Sbjct: 376 GDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAA 435

Query: 441 PSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDI 500
           PS+++++     T  S+ L+W +PD+PNGVIL+YE++YYEK+ +E +   +++      +
Sbjct: 436 PSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTV 495

Query: 501 KGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLL-VSVSGSVVL 559
           +GL     YVF VRART AGYG +S  +   T T             +++  S +G V L
Sbjct: 496 QGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFL 555

Query: 560 VVILIAAFVISRRRSKYSKAKQEADEEK------HLNQGVRTYVDPFTYEDPNQAVREFA 613
           + +++ A V +RRR  + +A  E  ++       H+  G++ Y+DPFTYEDPN+AVREFA
Sbjct: 556 IAVVVIAIVCNRRRG-FERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFA 614

Query: 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASI 673
           KEID SC+KIE+VIG GEFGEVCSG LK+PGKREI VAIKTLK+GYT+KQRRDFLSEASI
Sbjct: 615 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASI 674

Query: 674 MGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSG 733
           MGQFDHPN+IHLEGVVTK  PVMIITE+MENGSLD+FLR+NDG+FTVIQLVGMLRGI +G
Sbjct: 675 MGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAG 734

Query: 734 MKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDD-PEAAYTTR-GGKIPIRWT 791
           MKYL+DM+YVHRDLAARNILVNSNLVCKVSDFG+SR LEDD  +  YT+  GGKIPIRWT
Sbjct: 735 MKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWT 794

Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPI 851
           APEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVI AIE+ YRLPPPMDCP 
Sbjct: 795 APEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPS 854

Query: 852 ALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFS 911
           ALHQLMLDCWQK+R+ RPKFGQIVN LDK+IRNPNSLK     SS  N  LLD + P+++
Sbjct: 855 ALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYT 914

Query: 912 AVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQA 971
           +  +V +WL+AIKM +YK++F  AG+T+ + V  +  ED+ R+G+T   HQ KIL+S+Q 
Sbjct: 915 SFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQV 974

Query: 972 MRTQMQQM 979
           MR QM Q+
Sbjct: 975 MRAQMNQI 982


>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapiens]
          Length = 1005

 Score = 1170 bits (3027), Expect = 0.0
 Identities = 566/977 (57%), Positives = 722/977 (73%), Gaps = 32/977 (3%)

Query: 30   EVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWI 89
            EV LLD+ ++ G+ GW+  P  G W+ ++ +DE   PI TYQVCNVM P+QNNWLRT W+
Sbjct: 31   EVNLLDTSTIHGDWGWLTYPAHG-WDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWV 89

Query: 90   TREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIA 149
             R+GA+RVY EIKFTLRDCNS+PGV+GTCKETFNLYY ESD D     +E+QF+KIDTIA
Sbjct: 90   PRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIA 149

Query: 150  ADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVR 209
            ADESFT  D+G R +KLNTE+R VGPLSK+GFYLAFQD+GAC+A++S+R++YKKCP  VR
Sbjct: 150  ADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVR 209

Query: 210  NLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEER 269
            NLA F + +TGAD+SSLVEVRG CV +SEE+D PKMYC A+GEWLVPIG C+C+AG+EER
Sbjct: 210  NLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEER 269

Query: 270  SGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPP 329
               C AC++G+YK+   D  CA+CPPHS+S    A +C CD  ++RA  D  S  CTRPP
Sbjct: 270  RDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPP 329

Query: 330  SAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQ 389
            SAP+NLIS+VN TSV LEW+ P + GGR DI+YN VC++C     S+C  CGSG  + PQ
Sbjct: 330  SAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWA-LSRCEACGSGTRFVPQ 388

Query: 390  QNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQA 449
            Q  L    + + +LLAH NY+F I AVNGVS  +P P ++  V +TTNQAAPS + +++ 
Sbjct: 389  QTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQ 448

Query: 450  KEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSY 509
            +   + SV+L W EP++PNG+ILEYE+KYYEKD+  +SY  ++       + GL P T Y
Sbjct: 449  ERAGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRY 508

Query: 510  VFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVI 569
            VF VRART+AG G FS+ +EV T   P           + L  ++G VVL+++LI     
Sbjct: 509  VFQVRARTSAGCGRFSQAMEVETGK-PRPRYDTRTIVWICLTLITGLVVLLLLLIC---- 563

Query: 570  SRRRSKYSKAKQEADEEK-HLNQGV-------------------RTYVDPFTYEDPNQAV 609
             +R   YSKA Q++DEEK H   G                    + Y +P TYE+P +A 
Sbjct: 564  KKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQFYAEPHTYEEPGRAG 623

Query: 610  REFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLS 669
            R F +EI+AS I IEK+IG G+ GEVC GRL+VPG+R++ VAIK LKAGYT++QRRDFLS
Sbjct: 624  RSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQRDVPVAIKALKAGYTERQRRDFLS 683

Query: 670  EASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRG 729
            EASIMGQFDHPNII LEGVVT+ +  MI+TEYMENGSLD FLR +DG+FT++QLVGMLRG
Sbjct: 684  EASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRG 743

Query: 730  IGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIR 789
            +G+GM+YLSD+ YVHRDLAARN+LV+SNLVCKVSDFG+SRVLEDDP+AAYTT GGKIPIR
Sbjct: 744  VGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIR 803

Query: 790  WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDC 849
            WTAPEAIA+R F+SASDVWS+G+VMWEV++YGERPYW+M+N+DVI ++EEGYRLP PM C
Sbjct: 804  WTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGC 863

Query: 850  PIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDP---- 905
            P ALHQLMLDCW K+R+ RP+F QIV++LD LIR+P SL+ T T S  P  A +      
Sbjct: 864  PHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDL 923

Query: 906  -SSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNK 964
                     ++VGDWL +I+M RY+D+F A GY++L  V+ +N +D+  +GIT + HQ K
Sbjct: 924  RGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKK 983

Query: 965  ILSSVQAMRTQMQQMHG 981
            IL S+Q MR Q+    G
Sbjct: 984  ILGSIQTMRAQLTSTQG 1000


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 1168 bits (3021), Expect = 0.0
 Identities = 576/968 (59%), Positives = 725/968 (74%), Gaps = 20/968 (2%)

Query: 28  ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87
           A E TL+DS +   ELGW+  P   GWEEVS  DE    IRTYQVCNV E SQNNWLRT 
Sbjct: 18  AVEETLMDSTTATAELGWMVHP-PSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTK 76

Query: 88  WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFI----RENQFV 143
           +I R GA R+++E+KF++RDC+S+P V G+CKETFNLYYYE+D D          EN +V
Sbjct: 77  FIRRRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWV 136

Query: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203
           K+DTIAADESF+QVD+G R+MK+NTE+R  GP+S+ GFYLAFQD G C++L++VRVFY+K
Sbjct: 137 KVDTIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRK 196

Query: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262
           CP  ++N A F +T++GA+++SLV  RGSC+ N+EE DVP K+YC  DGEWLVPIG C+C
Sbjct: 197 CPRIIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMC 256

Query: 263 NAGHE--ERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDA 320
            AG E  E    C+ C  G +KA   D  C  CP +S +  EGAT+C C  G++RAD D 
Sbjct: 257 KAGFEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDP 316

Query: 321 ASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPC 380
             MPCT  PSAP  +IS+VNETS+ LEW+ P+++GGR+D+ YN++CK CG+G  + C  C
Sbjct: 317 LDMPCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGA-CTRC 375

Query: 381 GSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAA 440
           G  V Y P+Q GL   ++ I+DLLAHT YTFEI AVNGV+  +P   Q  SV +TTNQAA
Sbjct: 376 GDNVQYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAA 435

Query: 441 PSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDI 500
           PS+++++     T  S+ L+W +PD+PNGVIL+YE++YYEK+ +E +   +++      +
Sbjct: 436 PSAVSIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTV 495

Query: 501 KGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLL-VSVSGSVVL 559
           +GL     YVF VRART AGYG +S  +   T T             +++  S +G V L
Sbjct: 496 QGLKAGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEYQTSIQEKLPLIIGSSAAGLVFL 555

Query: 560 VVILIAAFVISRRRSKYSKAKQEADEEK------HLNQGVRTYVDPFTYEDPNQAVREFA 613
           + +++ A V +RR   + +A  E  ++       H+  G++ Y+DPFTYEDPN+AVREFA
Sbjct: 556 IAVVVIAIVCNRRG--FERADSEYTDKLQHYTSGHMTPGMKIYIDPFTYEDPNEAVREFA 613

Query: 614 KEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASI 673
           KEID SC+KIE+VIG GEFGEVCSG LK+PGKREI VAIKTLK+GYT+KQRRDFLSEASI
Sbjct: 614 KEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASI 673

Query: 674 MGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSG 733
           MGQFDHPN+IHLEGVVTK  PVMIITE+MENGSLD+FLR+NDG+FTVIQLVGMLRGI +G
Sbjct: 674 MGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAG 733

Query: 734 MKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDD-PEAAYTTR-GGKIPIRWT 791
           MKYL+DM+YVHRDLAARNILVNSNLVCKVSDFG+SR LEDD  +  YT+  GGKIPIRWT
Sbjct: 734 MKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRWT 793

Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPI 851
           APEAI YRKFTSASDVWSYGIVMWEVMSYGERPYWDM+NQDVI AIE+ YRLPPPMDCP 
Sbjct: 794 APEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYRLPPPMDCPS 853

Query: 852 ALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFS 911
           ALHQLMLDCWQK+R+ RPKFGQIVN LDK+IRNPNSLK     SS  N  LLD + P+++
Sbjct: 854 ALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNSLKAMAPLSSGINLPLLDRTIPDYT 913

Query: 912 AVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQA 971
           +  +V +WL+AIKM +YK++F  AG+T+ + V  +  ED+ R+G+T   HQ KIL+S+Q 
Sbjct: 914 SFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMMMEDILRVGVTLAGHQKKILNSIQV 973

Query: 972 MRTQMQQM 979
           MR QM Q+
Sbjct: 974 MRAQMNQI 981


>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
          Length = 984

 Score = 1164 bits (3010), Expect = 0.0
 Identities = 578/964 (59%), Positives = 717/964 (74%), Gaps = 15/964 (1%)

Query: 28  ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87
           A E TL+D+R+   ELGW A+P  G WEEVS  DE    IRTYQVCNV EP+QNNWL T 
Sbjct: 17  AMEETLMDTRTATAELGWTANPASG-WEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTT 75

Query: 88  WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDN----DKERFIRENQFV 143
           +I R GA R+Y E++FT+RDC+SLP V G+CKETFNLYYYE+D+     K  F  E  ++
Sbjct: 76  FINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYL 135

Query: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203
           K+DTIAADESF+QVD G R+MK+NTE+R  GPL++ GFYLAFQD GAC++L+SVRVF+KK
Sbjct: 136 KVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKK 195

Query: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262
           CP  V+N A FP+T+TGA+++SLV  RG+C+ N+EE DVP K+YC  DGEW+VPIG C C
Sbjct: 196 CPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTC 255

Query: 263 NAGHE-ERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAA 321
             G+E E S  C+AC  G +KA      C+ CP +S S  E +  CTC  G++RAD D  
Sbjct: 256 KPGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPP 315

Query: 322 SMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCG 381
            + CT  PS P N+IS VNETS+ LEW  P+ TGGR D++YN++CKKC A D   C  C 
Sbjct: 316 EVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRA-DRRSCSRCD 374

Query: 382 SGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAP 441
             V + P+Q GL   +VSI+ L AHT YTF+I A+NGVS  +P P Q VSV +TTNQAAP
Sbjct: 375 DNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAP 434

Query: 442 SSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIK 501
           S++ ++     T  S+ L+W +P++PNG+IL+YE++YYEK+ NE +  + R+      I 
Sbjct: 435 STVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARID 494

Query: 502 GLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVV 561
           GL P   YV  VRART AGYG FS  +   T T             ++  S +  VV VV
Sbjct: 495 GLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVV 554

Query: 562 ILIAAFVISRRRSKYSKAKQEADEEKHLNQG-----VRTYVDPFTYEDPNQAVREFAKEI 616
            L+A  ++  R+  YSK    +D+ +H + G     ++ Y+DPFTYEDPN+AVREFAKEI
Sbjct: 555 SLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEI 614

Query: 617 DASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQ 676
           D S +KIE+VIG GEFGEV  GRLK+PGKREI VAIKTLKAGY++KQRRDFLSEASIMGQ
Sbjct: 615 DVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQ 674

Query: 677 FDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKY 736
           FDHPNII LEGVVTK +PVMIITE+MENG+LD+FLR+NDG+FTVIQLVGMLRGI +GMKY
Sbjct: 675 FDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKY 734

Query: 737 LSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDD-PEAAYTTR-GGKIPIRWTAPE 794
           L++M+YVHRDLAARNILVNSNLVCKVSDFG+SR L+DD  +  YT+  GGKIP+RWTAPE
Sbjct: 735 LAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPE 794

Query: 795 AIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALH 854
           AIAYRKFTSASDVWSYGIVMWEVMS+GERPYWDMSNQDVI AIE+ YRLPPPMDCP ALH
Sbjct: 795 AIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALH 854

Query: 855 QLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVV 914
           QLMLDCWQK+R+ RP+F +IVN LDK+IRNP SLK   T ++ P+  LLD S P+F+A  
Sbjct: 855 QLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFT 914

Query: 915 SVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRT 974
           +V DWL AIKM +Y+D+F  AG+T+L+ V  +  EDL RIGIT   HQ KIL+S+ +MR 
Sbjct: 915 TVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGITLAGHQKKILNSIHSMRV 974

Query: 975 QMQQ 978
           Q+ Q
Sbjct: 975 QISQ 978


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 1130 bits (2922), Expect = 0.0
 Identities = 564/963 (58%), Positives = 699/963 (72%), Gaps = 19/963 (1%)

Query: 28  ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTD 87
           A E TL+D++ V  EL W + P E GWEEVS  DE   PIRTYQVCNV E SQNNWLRT 
Sbjct: 37  ALEETLMDTKWVTSELAWTSHP-ESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTG 95

Query: 88  WITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDND----KERFIRENQFV 143
           +I R   QRVY+E+KFT+RDCNS+P + G+CKETFNL+YYE+D+D       F  EN +V
Sbjct: 96  FIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYV 155

Query: 144 KIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKK 203
           K+DTIA DESF+++D G    ++NT++R  GPLSK GFYLAFQD GAC++L+SVR FYKK
Sbjct: 156 KVDTIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKK 211

Query: 204 CPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVP-KMYCGADGEWLVPIGNCLC 262
           C  T    A FP+T+TGA+ +SLV   G+C+ N+ E  VP K+YC  DGEW+VP+G C C
Sbjct: 212 CASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTC 271

Query: 263 NAGHEE--RSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDA 320
             GHE   +  +C+ C  G YKA   +  C  CPP+S +    A+ CTC   F+RAD+D+
Sbjct: 272 ATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDS 331

Query: 321 ASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKC-GAGDPSKCRP 379
           A   CT  PS P  +ISNVNETS+ LEWS P++ GGR D+ YNV+CKKC GAG  S C  
Sbjct: 332 ADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSR 391

Query: 380 CGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQA 439
           C   V + P+Q GL   +V I+ LLAHT YTFE+ AVNGVS  +P P +  +V +TTNQA
Sbjct: 392 CDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQA 451

Query: 440 APSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTD 499
           APS +  ++    +  S+ L+W  P+RPNGVIL+YE+KY+EK +   S   V +   +  
Sbjct: 452 APSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQ 509

Query: 500 IKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLV--SVSGSV 557
           + GL P   YV  VRART AGYG +S P E  T +              L+V  + +G V
Sbjct: 510 LDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLV 569

Query: 558 VLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEID 617
            +V +++ A V  R++   S ++     ++++  G++ Y+DPFTYEDPN+AVREFAKEID
Sbjct: 570 FVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEID 629

Query: 618 ASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQF 677
            SC+KIE+VIG GEFGEVC GRLK PG+RE+ VAIKTLK GYT++QRRDFLSEASIMGQF
Sbjct: 630 VSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQF 689

Query: 678 DHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYL 737
           DHPNII LEGVVTK +PVMI+TE+MEN +LD+FLR NDG+FTVIQLVGMLRGI +GMKYL
Sbjct: 690 DHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYL 749

Query: 738 SDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDP-EAAYTTR-GGKIPIRWTAPEA 795
           S+M+YVHRDLAARNILVNSNLVCKVSDFG+SR LEDDP +  YT+  GGKIPIRWTAPEA
Sbjct: 750 SEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEA 809

Query: 796 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQ 855
           IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVI A+E+ YRLPPPMDCP ALHQ
Sbjct: 810 IAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQ 869

Query: 856 LMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVS 915
           LMLDCW ++R+ RPKF QIVN LDKLIRN  SLK   +  S  +  LLD + P+++   +
Sbjct: 870 LMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTT 929

Query: 916 VGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQ 975
           VGDWL AIKM RYK++F +AG+ + + V  +  EDL RIG+T   HQ KILSS+Q MR Q
Sbjct: 930 VGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQ 989

Query: 976 MQQ 978
           M Q
Sbjct: 990 MNQ 992


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score =  971 bits (2511), Expect = 0.0
 Identities = 502/978 (51%), Positives = 663/978 (67%), Gaps = 25/978 (2%)

Query: 8   ALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEV-SIMDEKNTP 66
           A F+ L+G   A+  +      EV LLD  +  GELGW+  P   GW+ + +IM++   P
Sbjct: 8   ACFALLWGC--ALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM--P 63

Query: 67  IRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYY 126
           I  Y VCNVM   Q+NWLRT+W+ R  A+R++IE+KFT+RDCNS PG   +CKETFNLYY
Sbjct: 64  IYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYY 123

Query: 127 YESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQ 186
            ESD D     ++  F KIDTIA DE     D   R +KLN E R VGPL++KGFYLAFQ
Sbjct: 124 AESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQ 183

Query: 187 DVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK---DVP 243
           D+GAC+AL+SVRV+YKKCP  ++ LA FP+TI G+D  SL  V G+CV+++      + P
Sbjct: 184 DIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEP 243

Query: 244 KMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEG 303
           +M+C  DGEWLVPIG CLC AG+E+    CQAC  G++K  ++++ C +CP H+    EG
Sbjct: 244 RMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEG 303

Query: 304 ATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYN 363
           ATSC C+ GFFRA  D ASMPCTRPPSAP  L +      V L W+ PQ++GGR+DI Y+
Sbjct: 304 ATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYS 363

Query: 364 VVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYN 423
           V C++C   +  +C PC + V Y+   +GL  T V+++DL  H NYTF + A NGVS   
Sbjct: 364 VTCEQCWP-ESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLV 422

Query: 424 PNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQ 483
            +     + +V+ NQ  P  + L + +  T  S++++W  P      + +YEV Y +K  
Sbjct: 423 TSRSFRTA-SVSINQTEPPKVRL-EGRSTT--SLSVSWSIPPPQQSRVWKYEVTYRKKGD 478

Query: 484 NERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDG 543
           +  SY + RT   +  +  L P T+Y+  V+A T  G G  S+  E  T      +  +G
Sbjct: 479 SN-SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQT------LSPEG 531

Query: 544 ANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADE----EKHLNQGVRTYVDP 599
           + +  ++  V+  VVL+++L        RR K  +A+Q  ++    +    + ++TYVDP
Sbjct: 532 SGNLAVIGGVAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDP 591

Query: 600 FTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVP-GKREICVAIKTLKAG 658
            TYEDPNQAV +F  EI  SC+  +KVIG GEFGEV  G LK   GK+E+ VAIKTLKAG
Sbjct: 592 HTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAG 651

Query: 659 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRF 718
           YT+KQR DFL EA IMGQF H NII LEGV++K KP+MIITEYMENG+LD FLR+ DG F
Sbjct: 652 YTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEF 711

Query: 719 TVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAA 778
           +V+QLVGMLRGI +GMKYL++M+YVHRDLAARNILVNSNLVCKVSDFG+SRVLEDDPEA 
Sbjct: 712 SVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEAT 771

Query: 779 YTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE 838
           YTT GGKIPIRWTAPEAI+YRKFTSASDVWS+GIVMWEVM+YGERPYW++SN +V+KAI 
Sbjct: 772 YTTSGGKIPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAIN 831

Query: 839 EGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRP 898
           +G+RLP PMDCP A++QLM+ CWQ+ER+ RPKF  IV++LDKLIR P+SLK       R 
Sbjct: 832 DGFRLPTPMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRV 891

Query: 899 NTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITA 958
           +  L   S  E     +V +WL++IKM +Y ++F AAGYT +E VV +  +D+ RIG+  
Sbjct: 892 SIRLPSTSGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRL 951

Query: 959 ITHQNKILSSVQAMRTQM 976
             HQ +I  S+  ++ Q+
Sbjct: 952 PGHQKRIAYSLLGLKDQV 969


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score =  961 bits (2483), Expect = 0.0
 Identities = 494/966 (51%), Positives = 659/966 (68%), Gaps = 27/966 (2%)

Query: 28  ANEVTLLDSRSVQGELGWIASP-LEGGWEEVSIMDEKNTPIRTYQVCNVME-PSQNNWLR 85
           A E TLL+++    +L W+  P ++G WEE+S +DE+   +RTY+VC+V   P Q +WLR
Sbjct: 15  ALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLR 74

Query: 86  TDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIR----ENQ 141
           T W+ R GA  VY  ++FT+ +C SLP    +CKETF ++YYESD D    +     EN 
Sbjct: 75  TGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENP 134

Query: 142 FVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFY 201
           ++K+DT+AA+    +    +   K+N +   +GPLSK GFYLAFQD GAC+AL+S+ +FY
Sbjct: 135 YIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFY 194

Query: 202 KKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKD--VPKMYCGADGEWLV-PIG 258
           KKC     NL +FP+T+       +V V GSCV ++       P +YC  DG+W   P+ 
Sbjct: 195 KKCAQLTVNLTRFPETVP---RELVVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVT 251

Query: 259 NCLCNAGHEERSG--ECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRA 316
            C C  G E   G  +C+AC  G +K LS + +C  CP +S+S   G+  C C  G+FRA
Sbjct: 252 GCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRA 311

Query: 317 DNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSK 376
             D    PCT PPSAP +++S +N +S++LEWS+P  +GGR+D++Y + C++C  G    
Sbjct: 312 RTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG--GS 369

Query: 377 CRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTT 436
           C PCG  + + P    L    V +  L     YTFE+ A+NGVS     P     V VTT
Sbjct: 370 CAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTT 429

Query: 437 NQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKD-QNERSYRIVRTAA 495
           ++  P +++ ++    +  S++LAW  P  P+G +L+YEVKY+EK  +   S R ++T+ 
Sbjct: 430 DREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSE 489

Query: 496 RNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLVS--- 552
              +++GL    SY+  VRAR+ AGYG F +     T    S    +G    + L++   
Sbjct: 490 NRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDES----EGWREQLALIAGTA 545

Query: 553 VSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHL-NQGVRTYVDPFTYEDPNQAVRE 611
           V G V+++V+++ A +  R++S   +A+      ++L   G + Y+DPFTYEDPN+AVRE
Sbjct: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 605

Query: 612 FAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEA 671
           FAKEID S +KIE+VIG GEFGEVC GRLK PGK+E CVAIKTLK GYT++QRR+FLSEA
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEA 665

Query: 672 SIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIG 731
           SIMGQF+HPNII LEGVVT   PVMI+TE+MENG+LD+FLR NDG+FTVIQLVGMLRGI 
Sbjct: 666 SIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIA 725

Query: 732 SGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDD-PEAAYTTR-GGKIPIR 789
           SGM+YL++MSYVHRDLAARNILVNSNLVCKVSDFG+SR LE++  +  YT+  GGKIPIR
Sbjct: 726 SGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIR 785

Query: 790 WTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDC 849
           WTAPEAIA+RKFTSASD WSYGIVMWEVMS+GERPYWDMSNQDVI AIE+ YRLPPP DC
Sbjct: 786 WTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPPDC 845

Query: 850 PIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPE 909
           P +LHQLMLDCWQK+R+ RP+F Q+V+ LDK+IRNP SLK    E+   +  LLD   P 
Sbjct: 846 PTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLDQRQPH 905

Query: 910 FSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSV 969
           +SA  SVG+WL+AIKM RY+++F AAG+ + E V  ++ EDL RIG+T   HQ KIL+SV
Sbjct: 906 YSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKKILASV 965

Query: 970 QAMRTQ 975
           Q M++Q
Sbjct: 966 QHMKSQ 971


>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
          Length = 1008

 Score =  896 bits (2316), Expect = 0.0
 Identities = 464/1007 (46%), Positives = 656/1007 (65%), Gaps = 25/1007 (2%)

Query: 2    AGIFYFALFSCLFGICDAVTGSRVYP--ANEVTLLDSRSVQGELGWIASPLEGGWEEVSI 59
            AG     LF C   +C A+      P  A EV LLDS++ Q ELGW A P   GWEE+S 
Sbjct: 5    AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALP-SNGWEEISG 63

Query: 60   MDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCK 119
            +DE + PIRTYQVCNV+EP+Q+NWL+T WI+R   QR+++E++FTLRDC+S+PG  GTCK
Sbjct: 64   VDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCK 123

Query: 120  ETFNLYYYESDNDKERF---IRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPL 176
            ETFN+YY E++ D  R    +  ++  KIDTIAADESFTQ D+G+R MKLNTE+R++GPL
Sbjct: 124  ETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPL 183

Query: 177  SKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNN 236
            S++GF+LAFQDVGAC+ALVSVRV+YK+C  TVR LA FP T   +  S+LVEV G+CV +
Sbjct: 184  SRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAH 243

Query: 237  SEEK--DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCP 294
            SE +    P+M+CGADGEWLVP+G C C+AG +ER   C+AC  G+YK       C+ CP
Sbjct: 244  SEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCP 303

Query: 295  PHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSV--NLEWSSPQ 352
             HS ++   +T C C   + R+  D  S  CTRPPSAP +L  +++ + +   L W  P 
Sbjct: 304  EHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPA 363

Query: 353  NTGGRQDISYNVVCKKCGAGDPS-KCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTF 411
            ++GGR D++Y+++C +CG   P+  C PCG  V + P+Q GL+    ++  L     YT 
Sbjct: 364  DSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTV 423

Query: 412  EIWAVNGVSKYNPNPDQSVS-VTVTTNQAAPSSIALVQAKEVTRYSVALAWLEP---DRP 467
             + A+NGVS        + + VTV+T   AP     ++   V   SV+L+W EP     P
Sbjct: 424  RVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAP 483

Query: 468  NGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGD---F 524
                 EYE++YYEK Q+E++Y +V+T A    +  L P T YVF +RA +     +   F
Sbjct: 484  GANDTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSF 543

Query: 525  SEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEAD 584
            +  +EV T    +    D + + V+ V    +++++  +++   I RR   Y K   +A 
Sbjct: 544  NPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGGDAH 603

Query: 585  EEKHLNQGV-----RTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGR 639
            +E+ L         RT++DP +  D  QAV  FAKE+DA  + +E+ +G G FGE+C G 
Sbjct: 604  DEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGC 663

Query: 640  LKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIIT 699
            L++PG++E+ VA+  L+   +D QR  FL+EA  +GQFDH +I+ LEGVVT+   +MI+T
Sbjct: 664  LQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVT 723

Query: 700  EYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLV 759
            EYM +G+LD FLR+++G+    QL+G+L G+ S MKYLS+M YVHR LAAR++LV+S+LV
Sbjct: 724  EYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLV 783

Query: 760  CKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMS 819
            CK+S FG  R   D  EA YTT  G+ P  W APE + +  F+SASDVWS+GI+MWEVM+
Sbjct: 784  CKISGFG--RGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMA 841

Query: 820  YGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879
            +GERPYWDMS QDVIKA+E+G+RLPPP +CP  LH+LMLDCWQK+  +RP+F QI ++L 
Sbjct: 842  FGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILS 901

Query: 880  KLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTT 939
            K++++P   K   T   RP T L D +   F +  SVG WL+A+ + RYKD+F AAGY +
Sbjct: 902  KMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGS 961

Query: 940  LEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQMQQMHGRMVPV 986
            LEAV  +  +DL  +GI+   H+  +LS + A++ ++ Q+ G+ V V
Sbjct: 962  LEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQLQGQGVQV 1008


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score =  796 bits (2057), Expect = 0.0
 Identities = 439/962 (45%), Positives = 606/962 (62%), Gaps = 27/962 (2%)

Query: 28  ANEVTLLDSRSVQGELGWIASPLEGGW-EEVSIMDEKNTPIRTYQVCNVM-EPSQNNWLR 85
           A EVTL+D+   QGELGW+  P + GW E+  I++   TP+  YQ C +      ++WLR
Sbjct: 25  AKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILN--GTPLYMYQDCPMQGRRDTDHWLR 82

Query: 86  TDWITR-EGAQRVYIEIKFTLRDCNSLPGVMGT--CKETFNLYYYESDNDKERFIRENQF 142
           ++WI R E A RV++E++FT+RDC S PG  G   CKETFNL Y ESD D    +R   F
Sbjct: 83  SNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNLLYMESDQDVGIQLRRPLF 142

Query: 143 VKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYK 202
            K+ T+AAD+SFT  D+    +KLN E   +G L+++G YLAF + GAC+ALVSVRVFY+
Sbjct: 143 QKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLAFHNPGACVALVSVRVFYQ 202

Query: 203 KCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKD----VPKMYCGADGEWLVPIG 258
           +CP T+  LAQFPDT+ G   + LVEV G+C+ ++         P+M+C  DGEWLVP+G
Sbjct: 203 RCPETLNGLAQFPDTLPGP--AGLVEVAGTCLPHARASPRPSGAPRMHCSPDGEWLVPVG 260

Query: 259 NCLCNAGHEER-SGE-CQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRA 316
            C C  G+EE  SGE C AC  G Y+       C  CP  S +  EGAT CTC+ G +RA
Sbjct: 261 RCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTAESEGATICTCESGHYRA 320

Query: 317 DNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCG--AGDP 374
             +   + CT PPSAP NL  + + T ++L W  P +TGGRQD+ Y+V C +C   A D 
Sbjct: 321 PGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQDVRYSVRCSQCQGTAQDG 380

Query: 375 SKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTV 434
             C+PCG GVH++P   GL T  V +  L  + NYTF + A NGVS    +   S SV++
Sbjct: 381 GPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQNGVSGLGSSGHASTSVSI 440

Query: 435 TTNQA---APSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIV 491
           +   A   +  S+ LV+ KE  +  +  A   P  P G  L YE+    +D+ ER   ++
Sbjct: 441 SMGHAESLSGLSLRLVK-KEPRQLELTWAGSRPRSP-GANLTYELHVLNQDE-ERYQMVL 497

Query: 492 RTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRIIGDGANSTVLLV 551
                 T+   L P T+Y+  VR  T  G G FS   E  T+   SR +  G    V+  
Sbjct: 498 EPRVLLTE---LQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVSRGLTGGEIVAVIFG 554

Query: 552 SVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVRE 611
            + G+ +L+ IL+     ++R+ +  +  +  D ++     ++ YVD   YEDP Q   +
Sbjct: 555 LLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALD 614

Query: 612 FAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEA 671
           F +E+D + + ++ VIG GEFGEV  G L++P +    VAIKTLK      Q  +FL EA
Sbjct: 615 FTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREA 674

Query: 672 SIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIG 731
           +IMGQF HP+I+HLEGVVTK KP+MIITE+MENG+LDAFLR+ + +    QLV ML+GI 
Sbjct: 675 TIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIA 734

Query: 732 SGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWT 791
           SGM YLS+ +YVHRDLAARNILVN NL CKVSDFG++R+L DD +  Y T+GGKIPIRWT
Sbjct: 735 SGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLL-DDFDGTYETQGGKIPIRWT 793

Query: 792 APEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPI 851
           APEAIA+R FT+ASDVWS+GIVMWEV+S+G++PY +MSNQ+V+K+IE+GYRLPPP+DCP 
Sbjct: 794 APEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPA 853

Query: 852 ALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFS 911
            L++LM +CW  +R+ RP F ++   L++L+ NP+SL+       R    L   S  +  
Sbjct: 854 PLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGI 913

Query: 912 AVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAITHQNKILSSVQA 971
              +V +WL++I+M RY  +F +AG  T+E V+ +  EDL ++GIT   HQ +IL S+Q 
Sbjct: 914 PYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQG 973

Query: 972 MR 973
            +
Sbjct: 974 FK 975


>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
          Length = 1021

 Score =  783 bits (2021), Expect = 0.0
 Identities = 414/1001 (41%), Positives = 611/1001 (61%), Gaps = 66/1001 (6%)

Query: 28   ANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEP----SQNNW 83
            A E  LLD+     E+GW+  P  GGW+EVS++D++    RT++ C+V        Q+NW
Sbjct: 31   ALEEVLLDTTGETSEIGWLTYP-PGGWDEVSVLDDQRRLTRTFEACHVAGAPPGTGQDNW 89

Query: 84   LRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDN----DKERFIRE 139
            L+T ++ R GAQR +I + F++R C+SL    GTC+ETF LYY +++     D       
Sbjct: 90   LQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPDSPDSVSSWHL 149

Query: 140  NQFVKIDTIAADESFTQVD-----------------IGDRI-MKLNTEIRDVGPLSKKGF 181
             ++ K+DTIAADESF                      G R  ++LN + R  GPL+++GF
Sbjct: 150  KRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGF 209

Query: 182  YLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDT-ITGADTSSLVEVRGSCVNNSEEK 240
            Y+AFQD GAC+ALV+VR+F   CP  +R+ A FP+T  +GA  +SLV   G+CV ++E +
Sbjct: 210  YVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTCVAHAEPE 269

Query: 241  D----------VPKMYCGADGEWLVPIGNCLCNAGHEERSGE--CQACKIGYYKALSTDA 288
            +           P+++C  +G+W+V +G C C  G++   G+  CQAC  G YK+ + +A
Sbjct: 270  EDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLYKSSAGNA 329

Query: 289  TCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEW 348
             C+ CP  S++    A  C C  GF+RA +D    PCT PPSAP  L   V  +++ L W
Sbjct: 330  PCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGSALMLHW 389

Query: 349  SSPQNTGGRQDISYNVVCKKC------GAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITD 402
              P+  GGR D+ +NVVCK+C       +G    C  C   VH+ P+Q GL  ++V +  
Sbjct: 390  RLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVGG 449

Query: 403  LLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWL 462
            L AH  Y  E+ AVNGVS+ +P+P Q+ ++ V+T+   PS++ +V        S+ ++W 
Sbjct: 450  LRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASNSITVSWP 509

Query: 463  EPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNT-DIKGLNPLTSYVFHVRARTAAGY 521
            +PD+ NG IL+Y+++YY++ ++E S+    T+  NT  +  L+P   Y F VRARTAAG+
Sbjct: 510  QPDQTNGNILDYQLRYYDQAEDE-SHSFTLTSETNTATVTQLSPGHIYGFQVRARTAAGH 568

Query: 522  GDFSEPLEVTTNTVPSRIIGDGANSTVLLVSVSGSVVLVVILIAAF----VISRRRSKYS 577
            G +    +V   T+P   +       + LV  S    L  +L+AA     V+ +R+ + +
Sbjct: 569  GPYGG--KVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRKRRGT 626

Query: 578  KAKQEADEEKHLNQGVRTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCS 637
               ++  +      GV+ Y+DP TYEDP QA+RE A+E+D + IKIE+VIG G FGEV  
Sbjct: 627  GYTEQLQQYSSPGLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQ 686

Query: 638  GRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMI 697
            GRL+  G+RE  VAI+ L AG  +  +  FL  A+++GQF HPNI+ LEGVVTK +P+M+
Sbjct: 687  GRLQPRGRREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMV 746

Query: 698  ITEYMENGSLDAFLRKNDGRFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSN 757
            +TE+ME G LD+FLR+ +G+F+ +QLV M RG+ + M+YLS  ++VHR L+A ++LVNS+
Sbjct: 747  LTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSH 806

Query: 758  LVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEV 817
            LVCKV+  G            ++ +G    +RW APE IA+ K T++SDVWS+GI+MWEV
Sbjct: 807  LVCKVARLG------------HSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEV 854

Query: 818  MSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNM 877
            MSYGERPYWDMS Q+V+ AIE+ +RLPPP  CP  LH LMLD WQK+R+ RP F Q+V  
Sbjct: 855  MSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAA 914

Query: 878  LDKLIRNPNSLKRTGTESSRPNTALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGY 937
             DK+IR P++L+  G    RP+ ALL P + +F  + S   WL AI ++ Y+DNF+  G 
Sbjct: 915  FDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGL 974

Query: 938  TTLEAVVHVNQEDLARIGITAITHQNKILSSVQAMRTQMQQ 978
             T   V  ++ EDL  +GIT   HQ K+L  +Q ++  ++Q
Sbjct: 975  CTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQ 1015


>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
           sapiens]
          Length = 539

 Score =  683 bits (1763), Expect = 0.0
 Identities = 319/507 (62%), Positives = 399/507 (78%), Gaps = 3/507 (0%)

Query: 27  PANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRT 86
           P+NEV LLDS+++QGELGWI+ P  G WEE+S +DE  TPIRTYQVCNVM+ SQNNWLRT
Sbjct: 26  PSNEVNLLDSKTIQGELGWISYPSHG-WEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84

Query: 87  DWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKID 146
           +W+ R  AQ++Y+E+KFTLRDCNS+P V+GTCKETFNLYY ESD+D     RE+QF KID
Sbjct: 85  NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144

Query: 147 TIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPL 206
           TIAADESFTQ+D+GDRI+KLNTEIR+VGP++KKGFYLAFQDVGAC+ALVSVRV++KKCP 
Sbjct: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204

Query: 207 TVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGH 266
           TV+NLA FPDT+   D+ SLVEVRGSCVNNS+E+D P+MYC  +GEWLVPIG C CNAG+
Sbjct: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGY 263

Query: 267 EERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCT 326
           EER   CQAC+ G+YKAL  +  CAKCPPHS +  +G+ +C C+  +FRAD D  SM CT
Sbjct: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323

Query: 327 RPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHY 386
           RPPS+P N+ISN+NETSV L+WS P +TGGR+D+++N++CKKCG  +  +C PC   V +
Sbjct: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG-WNIKQCEPCSPNVRF 382

Query: 387 TPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIAL 446
            P+Q GL  T V++TDLLAHTNYTFEI AVNGVS+ +  P Q  +V++TTNQAAPS +  
Sbjct: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442

Query: 447 VQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPL 506
           ++    +R S++L+W EP+ PNG+IL+YEVKYYEK + E SY I+R    N  I  L P 
Sbjct: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502

Query: 507 TSYVFHVRARTAAGYGDFSEPLEVTTN 533
           T YVF +RARTAAGYG  S   E  T+
Sbjct: 503 TIYVFQIRARTAAGYGTNSRKFEFETS 529


>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
           sapiens]
          Length = 495

 Score =  537 bits (1383), Expect = e-152
 Identities = 247/410 (60%), Positives = 311/410 (75%), Gaps = 2/410 (0%)

Query: 30  EVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRTDWI 89
           EV LLD+ ++ G+ GW+  P  G W+ ++ +DE   PI TYQVCNVM P+QNNWLRT W+
Sbjct: 31  EVNLLDTSTIHGDWGWLTYPAHG-WDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWV 89

Query: 90  TREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKIDTIA 149
            R+GA+RVY EIKFTLRDCNS+PGV+GTCKETFNLYY ESD D     +E+QF+KIDTIA
Sbjct: 90  PRDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIA 149

Query: 150 ADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVR 209
           ADESFT  D+G R +KLNTE+R VGPLSK+GFYLAFQD+GAC+A++S+R++YKKCP  VR
Sbjct: 150 ADESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVR 209

Query: 210 NLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGHEER 269
           NLA F + +TGAD+SSLVEVRG CV +SEE+D PKMYC A+GEWLVPIG C+C+AG+EER
Sbjct: 210 NLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEER 269

Query: 270 SGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCTRPP 329
              C AC++G+YK+   D  CA+CPPHS+S    A +C CD  ++RA  D  S  CTRPP
Sbjct: 270 RDACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPP 329

Query: 330 SAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHYTPQ 389
           SAP+NLIS+VN TSV LEW+ P + GGR DI+YN VC++C     S+C  CGSG  + PQ
Sbjct: 330 SAPVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRC-PWALSRCEACGSGTRFVPQ 388

Query: 390 QNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQA 439
           Q  L    + + +LLAH NY+F I AVNGVS  +P P ++  V +TTNQA
Sbjct: 389 QTSLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438


>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
          Length = 295

 Score =  320 bits (819), Expect = 5e-87
 Identities = 160/284 (56%), Positives = 209/284 (73%), Gaps = 8/284 (2%)

Query: 2   AGIFYFALFSCLFGICDAVTGSRVYP--ANEVTLLDSRSVQGELGWIASPLEGGWEEVSI 59
           AG     LF C   +C A+      P  A EV LLDS++ Q ELGW A P   GWEE+S 
Sbjct: 5   AGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALP-SNGWEEISG 63

Query: 60  MDEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCK 119
           +DE + PIRTYQVCNV+EP+Q+NWL+T WI+R   QR+++E++FTLRDC+S+PG  GTCK
Sbjct: 64  VDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCK 123

Query: 120 ETFNLYYYESDNDKERF---IRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPL 176
           ETFN+YY E++ D  R    +  ++  KIDTIAADESFTQ D+G+R MKLNTE+R++GPL
Sbjct: 124 ETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPL 183

Query: 177 SKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNN 236
           S++GF+LAFQDVGAC+ALVSVRV+YK+C  TVR LA FP T   +  S+LVEV G+CV +
Sbjct: 184 SRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAH 243

Query: 237 SEEK--DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKI 278
           SE +    P+M+CGADGEWLVP+G C C+AG +ER   C+  ++
Sbjct: 244 SEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEGIQL 287


>gi|30795229 hemopoietic cell kinase isoform p61HCK [Homo sapiens]
          Length = 526

 Score =  231 bits (590), Expect = 2e-60
 Identities = 128/310 (41%), Positives = 190/310 (61%), Gaps = 13/310 (4%)

Query: 573 RSKYSKAKQEADEEKHLNQGVRTYVD-PFTYEDPNQAVREFAKEIDASCIKIEKVIGVGE 631
           RS +S  ++  D  K  N G+   +  P     P +   + A EI    +K+EK +G G+
Sbjct: 213 RSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQ 272

Query: 632 FGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTK 691
           FGEV         K    VA+KT+K G    +   FL+EA++M    H  ++ L  VVTK
Sbjct: 273 FGEVWMATYNKHTK----VAVKTMKPGSMSVEA--FLAEANVMKTLQHDKLVKLHAVVTK 326

Query: 692 CKPVMIITEYMENGSLDAFLRKNDG-RFTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAAR 750
            +P+ IITE+M  GSL  FL+ ++G +  + +L+     I  GM ++   +Y+HRDL A 
Sbjct: 327 -EPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAA 385

Query: 751 NILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWS 809
           NILV+++LVCK++DFG++RV+ED+    YT R G K PI+WTAPEAI +  FT  SDVWS
Sbjct: 386 NILVSASLVCKIADFGLARVIEDNE---YTAREGAKFPIKWTAPEAINFGSFTIKSDVWS 442

Query: 810 YGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRP 869
           +GI++ E+++YG  PY  MSN +VI+A+E GYR+P P +CP  L+ +M+ CW+    +RP
Sbjct: 443 FGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERP 502

Query: 870 KFGQIVNMLD 879
            F  I ++LD
Sbjct: 503 TFEYIQSVLD 512


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score =  227 bits (578), Expect = 5e-59
 Identities = 118/267 (44%), Positives = 174/267 (65%), Gaps = 12/267 (4%)

Query: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674
           EI    +++ K +G G+FGEV  G      K    VAIKTLK G    +   FL EA IM
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQIM 318

Query: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI-QLVGMLRGIGSG 733
            +  H  ++ L  VV++ +P+ I+TEYM  GSL  FL+  +GR   +  LV M   + +G
Sbjct: 319 KKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAG 377

Query: 734 MKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR-GGKIPIRWTA 792
           M Y+  M+Y+HRDL + NILV + L+CK++DFG++R++ED+    YT R G K PI+WTA
Sbjct: 378 MAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKWTA 434

Query: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIA 852
           PEA  Y +FT  SDVWS+GI++ E+++ G  PY  M+N++V++ +E GYR+P P DCPI+
Sbjct: 435 PEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPIS 494

Query: 853 LHQLMLDCWQKERSDRPKFGQIVNMLD 879
           LH+LM+ CW+K+  +RP F  + + L+
Sbjct: 495 LHELMIHCWKKDPEERPTFEYLQSFLE 521


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score =  224 bits (570), Expect = 4e-58
 Identities = 124/281 (44%), Positives = 176/281 (62%), Gaps = 12/281 (4%)

Query: 601 TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT 660
           T +   Q + + A EI    +++E  +G G FGEV  G      K    VAIKTLK G  
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTK----VAIKTLKPGTM 312

Query: 661 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV 720
             +   FL EA IM +  H  ++ L  VV++ +P+ I+TE+M  GSL  FL++ DG++  
Sbjct: 313 MPEA--FLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKYLK 369

Query: 721 I-QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAY 779
           + QLV M   I  GM Y+  M+Y+HRDL A NILV  NLVCK++DFG++R++ED+    Y
Sbjct: 370 LPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNE---Y 426

Query: 780 TTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE 838
           T R G K PI+WTAPEA  Y +FT  SDVWS+GI+  E+++ G  PY  M N++V++ +E
Sbjct: 427 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVE 486

Query: 839 EGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879
            GYR+P P  CP +LH+LM  CW+K+  +RP F  I + L+
Sbjct: 487 RGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  223 bits (569), Expect = 5e-58
 Identities = 125/281 (44%), Positives = 173/281 (61%), Gaps = 12/281 (4%)

Query: 601 TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT 660
           T +   Q + + A EI    +++E  +G G FGEV  G      +    VAIKTLK G  
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305

Query: 661 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV 720
             +   FL EA +M +  H  ++ L  VV++ +P+ I+TEYM  GSL  FL+   G++  
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLR 362

Query: 721 I-QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAY 779
           + QLV M   I SGM Y+  M+YVHRDL A NILV  NLVCKV+DFG++R++ED+    Y
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---Y 419

Query: 780 TTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE 838
           T R G K PI+WTAPEA  Y +FT  SDVWS+GI++ E+ + G  PY  M N++V+  +E
Sbjct: 420 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 479

Query: 839 EGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879
            GYR+P P +CP +LH LM  CW+KE  +RP F  +   L+
Sbjct: 480 RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score =  223 bits (569), Expect = 5e-58
 Identities = 125/281 (44%), Positives = 173/281 (61%), Gaps = 12/281 (4%)

Query: 601 TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT 660
           T +   Q + + A EI    +++E  +G G FGEV  G      +    VAIKTLK G  
Sbjct: 250 TSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR----VAIKTLKPGTM 305

Query: 661 DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV 720
             +   FL EA +M +  H  ++ L  VV++ +P+ I+TEYM  GSL  FL+   G++  
Sbjct: 306 SPEA--FLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGETGKYLR 362

Query: 721 I-QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAY 779
           + QLV M   I SGM Y+  M+YVHRDL A NILV  NLVCKV+DFG++R++ED+    Y
Sbjct: 363 LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE---Y 419

Query: 780 TTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIE 838
           T R G K PI+WTAPEA  Y +FT  SDVWS+GI++ E+ + G  PY  M N++V+  +E
Sbjct: 420 TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVE 479

Query: 839 EGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879
            GYR+P P +CP +LH LM  CW+KE  +RP F  +   L+
Sbjct: 480 RGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLE 520


>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
          Length = 534

 Score =  223 bits (569), Expect = 5e-58
 Identities = 118/269 (43%), Positives = 173/269 (64%), Gaps = 12/269 (4%)

Query: 613 AKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEAS 672
           A E+    + +EK +G G F EV  G      K    VAIKTLK G    +   FL EA 
Sbjct: 260 AWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTK----VAIKTLKPGTMSPE--SFLEEAQ 313

Query: 673 IMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI-QLVGMLRGIG 731
           IM +  H  ++ L  VV++ +P+ I+TEYM  GSL  FL+  +GR   +  LV M   + 
Sbjct: 314 IMKKLKHDKLVQLYAVVSE-EPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVA 372

Query: 732 SGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR-GGKIPIRW 790
           +GM Y+  M+Y+HRDL + NILV + L+CK++DFG++R++ED+    YT R G K PI+W
Sbjct: 373 AGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNE---YTARQGAKFPIKW 429

Query: 791 TAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCP 850
           TAPEA  Y +FT  SDVWS+GI++ E+++ G  PY  M+N++V++ +E GYR+P P DCP
Sbjct: 430 TAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCP 489

Query: 851 IALHQLMLDCWQKERSDRPKFGQIVNMLD 879
           I+LH+LM+ CW+K+  +RP F  + + L+
Sbjct: 490 ISLHELMIHCWKKDPEERPTFEYLQSFLE 518


>gi|27886593 PTK2 protein tyrosine kinase 2 isoform b [Homo sapiens]
          Length = 1074

 Score =  220 bits (560), Expect = 6e-57
 Identities = 133/369 (36%), Positives = 194/369 (52%), Gaps = 15/369 (4%)

Query: 538 RIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYV 597
           R++   + S ++     G   L  I   A    +    ++ +  E D+   +     TY 
Sbjct: 371 RLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYT 430

Query: 598 DPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKA 657
            P T        R++  EI    I++ + IG G+FG+V  G    P    + VAIKT K 
Sbjct: 431 MPST--------RDY--EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN 480

Query: 658 GYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR 717
             +D  R  FL EA  M QFDHP+I+ L GV+T+  PV II E    G L +FL+     
Sbjct: 481 CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYS 539

Query: 718 FTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEA 777
             +  L+     + + + YL    +VHRD+AARN+LV+SN   K+ DFG+SR +ED    
Sbjct: 540 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--T 597

Query: 778 AYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI 837
            Y    GK+PI+W APE+I +R+FTSASDVW +G+ MWE++ +G +P+  + N DVI  I
Sbjct: 598 YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 657

Query: 838 EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSL--KRTGTES 895
           E G RLP P +CP  L+ LM  CW  + S RP+F ++   L  ++    +   +R   ES
Sbjct: 658 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES 717

Query: 896 SRPNTALLD 904
            R  T   D
Sbjct: 718 RRQATVSWD 726


>gi|24476013 PTK2 protein tyrosine kinase 2 isoform a [Homo sapiens]
          Length = 1052

 Score =  220 bits (560), Expect = 6e-57
 Identities = 133/369 (36%), Positives = 194/369 (52%), Gaps = 15/369 (4%)

Query: 538 RIIGDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYV 597
           R++   + S ++     G   L  I   A    +    ++ +  E D+   +     TY 
Sbjct: 349 RLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYT 408

Query: 598 DPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKA 657
            P T        R++  EI    I++ + IG G+FG+V  G    P    + VAIKT K 
Sbjct: 409 MPST--------RDY--EIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKN 458

Query: 658 GYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGR 717
             +D  R  FL EA  M QFDHP+I+ L GV+T+  PV II E    G L +FL+     
Sbjct: 459 CTSDSVREKFLQEALTMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYS 517

Query: 718 FTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEA 777
             +  L+     + + + YL    +VHRD+AARN+LV+SN   K+ DFG+SR +ED    
Sbjct: 518 LDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS--T 575

Query: 778 AYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAI 837
            Y    GK+PI+W APE+I +R+FTSASDVW +G+ MWE++ +G +P+  + N DVI  I
Sbjct: 576 YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI 635

Query: 838 EEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSL--KRTGTES 895
           E G RLP P +CP  L+ LM  CW  + S RP+F ++   L  ++    +   +R   ES
Sbjct: 636 ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES 695

Query: 896 SRPNTALLD 904
            R  T   D
Sbjct: 696 RRQATVSWD 704


>gi|162287326 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform B [Homo sapiens]
          Length = 491

 Score =  219 bits (558), Expect = 1e-56
 Identities = 116/269 (43%), Positives = 172/269 (63%), Gaps = 11/269 (4%)

Query: 613 AKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEAS 672
           A EI    IK+ K +G G+FGEV  G      K    VA+KTLK G    Q   FL EA+
Sbjct: 218 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 271

Query: 673 IMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI-QLVGMLRGIG 731
           +M    H  ++ L  VVT+ +P+ IITEYM  GSL  FL+ ++G   ++ +L+     I 
Sbjct: 272 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 331

Query: 732 SGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR-GGKIPIRW 790
            GM Y+   +Y+HRDL A N+LV+ +L+CK++DFG++RV+ED+    YT R G K PI+W
Sbjct: 332 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTAREGAKFPIKW 388

Query: 791 TAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCP 850
           TAPEAI +  FT  SDVWS+GI+++E+++YG+ PY   +N DV+ A+ +GYR+P   +CP
Sbjct: 389 TAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCP 448

Query: 851 IALHQLMLDCWQKERSDRPKFGQIVNMLD 879
             L+ +M  CW+++  +RP F  + ++LD
Sbjct: 449 DELYDIMKMCWKEKAEERPTFDYLQSVLD 477


>gi|4505055 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
           isoform A [Homo sapiens]
          Length = 512

 Score =  219 bits (558), Expect = 1e-56
 Identities = 116/269 (43%), Positives = 172/269 (63%), Gaps = 11/269 (4%)

Query: 613 AKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEAS 672
           A EI    IK+ K +G G+FGEV  G      K    VA+KTLK G    Q   FL EA+
Sbjct: 239 AWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK----VAVKTLKPGTMSVQA--FLEEAN 292

Query: 673 IMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI-QLVGMLRGIG 731
           +M    H  ++ L  VVT+ +P+ IITEYM  GSL  FL+ ++G   ++ +L+     I 
Sbjct: 293 LMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIA 352

Query: 732 SGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTR-GGKIPIRW 790
            GM Y+   +Y+HRDL A N+LV+ +L+CK++DFG++RV+ED+    YT R G K PI+W
Sbjct: 353 EGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE---YTAREGAKFPIKW 409

Query: 791 TAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCP 850
           TAPEAI +  FT  SDVWS+GI+++E+++YG+ PY   +N DV+ A+ +GYR+P   +CP
Sbjct: 410 TAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCP 469

Query: 851 IALHQLMLDCWQKERSDRPKFGQIVNMLD 879
             L+ +M  CW+++  +RP F  + ++LD
Sbjct: 470 DELYDIMKMCWKEKAEERPTFDYLQSVLD 498


>gi|112789548 lymphocyte-specific protein tyrosine kinase precursor
           [Homo sapiens]
          Length = 509

 Score =  219 bits (557), Expect = 1e-56
 Identities = 120/283 (42%), Positives = 177/283 (62%), Gaps = 12/283 (4%)

Query: 599 PFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAG 658
           P   + P +   E   E+    +K+ + +G G+FGEV  G      K    VA+K+LK G
Sbjct: 223 PCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTK----VAVKSLKQG 278

Query: 659 YTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDG-R 717
                   FL+EA++M Q  H  ++ L  VVT+ +P+ IITEYMENGSL  FL+   G +
Sbjct: 279 SMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVDFLKTPSGIK 335

Query: 718 FTVIQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEA 777
            T+ +L+ M   I  GM ++ + +Y+HRDL A NILV+  L CK++DFG++R++ED+   
Sbjct: 336 LTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNE-- 393

Query: 778 AYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKA 836
            YT R G K PI+WTAPEAI Y  FT  SDVWS+GI++ E++++G  PY  M+N +VI+ 
Sbjct: 394 -YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQN 452

Query: 837 IEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLD 879
           +E GYR+  P +CP  L+QLM  CW++   DRP F  + ++L+
Sbjct: 453 LERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,986,785
Number of Sequences: 37866
Number of extensions: 1737296
Number of successful extensions: 7900
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 587
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 4314
Number of HSP's gapped (non-prelim): 2128
length of query: 986
length of database: 18,247,518
effective HSP length: 112
effective length of query: 874
effective length of database: 14,006,526
effective search space: 12241703724
effective search space used: 12241703724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.