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Search of human proteins with 4557888
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557888 keratin 18 [Homo sapiens]
(430 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40354195 keratin 18 [Homo sapiens] 821 0.0
gi|4557888 keratin 18 [Homo sapiens] 821 0.0
gi|15431310 keratin 14 [Homo sapiens] 351 8e-97
gi|24430192 keratin 16 [Homo sapiens] 339 2e-93
gi|24430190 keratin 15 [Homo sapiens] 335 4e-92
gi|24234699 keratin 19 [Homo sapiens] 334 8e-92
gi|4557701 keratin 17 [Homo sapiens] 329 3e-90
gi|195972866 keratin 10 [Homo sapiens] 324 8e-89
gi|131412225 keratin 13 isoform a [Homo sapiens] 323 2e-88
gi|131412228 keratin 13 isoform b [Homo sapiens] 322 3e-88
gi|4504927 keratin 36 [Homo sapiens] 313 2e-85
gi|192807292 keratin 24 [Homo sapiens] 312 4e-85
gi|27894337 keratin 20 [Homo sapiens] 308 5e-84
gi|4557699 keratin 12 [Homo sapiens] 303 3e-82
gi|94538345 keratin 35 [Homo sapiens] 299 4e-81
gi|27734744 hypothetical protein LOC284085 [Homo sapiens] 298 5e-81
gi|14917117 keratin 33A [Homo sapiens] 293 2e-79
gi|14917115 keratin 31 [Homo sapiens] 293 2e-79
gi|116488398 keratin 32 [Homo sapiens] 291 8e-79
gi|10337581 type I hair keratin 3B [Homo sapiens] 286 3e-77
gi|114431246 keratin 25D [Homo sapiens] 284 1e-76
gi|153945736 keratin 27 [Homo sapiens] 281 1e-75
gi|14917119 keratin 34 [Homo sapiens] 275 6e-74
gi|31559829 keratin 25 [Homo sapiens] 270 1e-72
gi|55956899 keratin 9 [Homo sapiens] 270 2e-72
gi|148277620 type I hair keratin KA35 [Homo sapiens] 261 1e-69
gi|31559815 keratin 26 [Homo sapiens] 259 4e-69
gi|27894339 keratin 23 [Homo sapiens] 255 6e-68
gi|125490370 type I hair keratin KA36 [Homo sapiens] 252 4e-67
gi|15431318 keratin 38 [Homo sapiens] 250 2e-66
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 821 bits (2120), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS 60
MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS
Sbjct: 1 MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS 60
Query: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG
Sbjct: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
Query: 121 PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN
Sbjct: 121 PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
Query: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP
Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
Query: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR
Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
Query: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA
Sbjct: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
Query: 361 QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS 420
QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS
Sbjct: 361 QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS 420
Query: 421 ETNDTKVLRH 430
ETNDTKVLRH
Sbjct: 421 ETNDTKVLRH 430
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 821 bits (2120), Expect = 0.0
Identities = 430/430 (100%), Positives = 430/430 (100%)
Query: 1 MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS 60
MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS
Sbjct: 1 MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS 60
Query: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG
Sbjct: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
Query: 121 PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN
Sbjct: 121 PQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
Query: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP
Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
Query: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR
Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
Query: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA
Sbjct: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
Query: 361 QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS 420
QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS
Sbjct: 361 QEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVS 420
Query: 421 ETNDTKVLRH 430
ETNDTKVLRH
Sbjct: 421 ETNDTKVLRH 430
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 351 bits (900), Expect = 8e-97
Identities = 204/427 (47%), Positives = 287/427 (67%), Gaps = 18/427 (4%)
Query: 17 GSVQAPSY--GARPVSSAASVYAGA-------GGSGSRISVSRSTSFRGGMGSG---GLA 64
GS +APS G VSS+ GA GG S S S + F GG G G GL
Sbjct: 38 GSCRAPSTYGGGLSVSSSRFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLG 97
Query: 65 TGIAGGLAGMGG--IQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP- 121
G GG AG G + +EK TMQ+LNDRLASYLD+VR+LE N LE KIR+ +++ P
Sbjct: 98 GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPA 157
Query: 122 QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEND 181
+++D+S YFK IEDLR +I TVDNA ++LQIDNARLAADDFR KYETEL +R SVE D
Sbjct: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
Query: 182 IHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPK 241
I+GLR+V+D+ + R LE +IE+LKEEL ++KKNHEEE+ L+ Q+ + VE+DA
Sbjct: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGD-VNVEMDAAP 276
Query: 242 SQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRR 301
DL++I+ ++R QY+++A KNR++ ++++ + EE V T S V + ++ ++ELRR
Sbjct: 277 GVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRR 336
Query: 302 TVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQ 361
T+Q+LEI+L S ++KASLENSL E + RY +Q+ Q+ ++ +E +LAQ R E ++Q Q
Sbjct: 337 TMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQ 396
Query: 362 EYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSE 421
EY+ LL++K +LE EIATYRRLLE GED +L + SS S + T++ R + KV+ +
Sbjct: 397 EYKILLDVKTRLEQEIATYRRLLE-GEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVM-D 454
Query: 422 TNDTKVL 428
+D KV+
Sbjct: 455 VHDGKVV 461
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 339 bits (870), Expect = 2e-93
Identities = 195/412 (47%), Positives = 273/412 (66%), Gaps = 21/412 (5%)
Query: 17 GSVQAPS-YG------ARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAG 69
GS +APS YG +R S A G G G S S + F GG G GGL G G
Sbjct: 38 GSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYG-GGLGAGFGG 96
Query: 70 GL-AGMGG---------IQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKK 119
GL AG GG + +EK TMQ+LNDRLASYLD+VR+LE N LE KIR+ +++
Sbjct: 97 GLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ 156
Query: 120 GP-QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSV 178
P +++D+S YFK IEDLR +I A T++NA+ +LQIDNARLAADDFR KYE ELA+RQ+V
Sbjct: 157 RPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTV 216
Query: 179 ENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVD 238
E D++GLR+V+D+ + R LE +IE LKEEL +++KNHEEE+ L+ Q + VE+D
Sbjct: 217 EADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGD-VNVEMD 275
Query: 239 APKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTE 298
A DL++I+ ++R QY+++A KNR + + ++ + EE V + S V ++ + +TE
Sbjct: 276 AAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTE 335
Query: 299 LRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQR 358
LRR +Q LEI+L S ++KASLENSL E + RY +Q+ Q+ G++ +E +LAQ R E ++
Sbjct: 336 LRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQ 395
Query: 359 QAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTT 410
Q+QEY+ LL++K +LE EIATYRRLLE GED +L S S + + T+
Sbjct: 396 QSQEYQILLDVKTRLEQEIATYRRLLE-GEDAHLSSQQASGQSYSSREVFTS 446
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 335 bits (860), Expect = 4e-92
Identities = 187/413 (45%), Positives = 268/413 (64%), Gaps = 19/413 (4%)
Query: 25 GARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS---GGLATGIAGGLAGM-----GG 76
G+R +S++++ + +G G R F GG GS GG G+ GG G GG
Sbjct: 40 GSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGG 99
Query: 77 IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVR--DWSHYFKI 132
+ NEK TMQ+LNDRLASYLD+VR+LE N LE KI + +K+ P D+S YFK
Sbjct: 100 LLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKT 159
Query: 133 IEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDT 192
IE+LR +I A T+DN+R++L+IDNARLAADDFR+KYE ELA+RQ VE DI+GLR+V+D+
Sbjct: 160 IEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDEL 219
Query: 193 NITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADI 252
+ R LE +IE L EEL ++KKNHEEE+K +Q+A + VE+DA DL +++A++
Sbjct: 220 TLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQ-VNVEMDAAPGVDLTRVLAEM 278
Query: 253 RAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDS 312
R QY+ +A KNR +++ ++ + EE V + + + ++T +T+LRRT+Q LEI+L S
Sbjct: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338
Query: 313 MRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVK 372
++KA LENSL E E RYA Q++Q+ G++ LE++L++ R E + Q QEY+ LL+IK +
Sbjct: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398
Query: 373 LEAEIATYRRLLEDGED-----FNLGDALDSSNSMQTIQKTTTRRIVDGKVVS 420
LE EIATYR LLE G+D + +A + VDG+VVS
Sbjct: 399 LEQEIATYRSLLE-GQDAKMAGIGIREASSGGGGSSSNFHINVEESVDGQVVS 450
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 334 bits (857), Expect = 8e-92
Identities = 182/389 (46%), Positives = 266/389 (68%), Gaps = 12/389 (3%)
Query: 6 RSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRIS----VSRSTSFRGGMGSG 61
+S+ ++++ LG +G A S++ G+GG G +S VS S+S G G G
Sbjct: 8 QSSATSSFGGLGGGSV-RFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYG 66
Query: 62 GLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP 121
G+ T G LAG NEK TMQ+LNDRLASYLD+VR+LE N LE KIR+ +K+GP
Sbjct: 67 GVLTASDGLLAG-----NEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGP 121
Query: 122 -QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
RD+SHY+ I+DLR +I T++N+RIVLQIDNARLAADDFR K+ETE A+R SVE
Sbjct: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181
Query: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
DI+GLR+V+D+ + R LE +IE LKEEL ++KKNHEEE+ L+ Q+ ++VEVD+
Sbjct: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQ-VSVEVDSA 240
Query: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
DLAKI++D+R+QY+ +A +NR++ + +++ + EE V + ++ + + +T+LR
Sbjct: 241 PGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLR 300
Query: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
RT+Q LEI+L S ++KA+LE++L E EAR+ Q+ + ++ +E++L RA+ +RQ
Sbjct: 301 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN 360
Query: 361 QEYEALLNIKVKLEAEIATYRRLLEDGED 389
QEY+ L++IK +LE EIATYR LLE ED
Sbjct: 361 QEYQRLMDIKSRLEQEIATYRSLLEGQED 389
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 329 bits (843), Expect = 3e-90
Identities = 185/386 (47%), Positives = 261/386 (67%), Gaps = 12/386 (3%)
Query: 39 AGGSGSRI---SVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYL 95
AGG GS + S S SF G G G G+ G LAG EK TMQ+LNDRLASYL
Sbjct: 45 AGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAG-----GEKATMQNLNDRLASYL 99
Query: 96 DRVRSLETENRRLESKIREHLEKKGP-QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQI 154
D+VR+LE N LE KIR+ +++ P RD+S Y++ IE+L+ +I TVDNA I+LQI
Sbjct: 100 DKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQI 159
Query: 155 DNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMK 214
DNARLAADDFR K+ETE A+R SVE DI+GLR+V+D+ + R LE +IE LKEEL ++K
Sbjct: 160 DNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLK 219
Query: 215 KNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQ 274
KNHEEE+ L+ Q+ + VE+DA DL++I+ ++R QY+++A KNR++ + ++ +
Sbjct: 220 KNHEEEMNALRGQVGGE-INVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSK 278
Query: 275 IEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQ 334
EE V T S V + ++ ++ELRRT+Q+LEI+L S ++KASLE +L E E RY +Q
Sbjct: 279 TEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQ 338
Query: 335 MEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGD 394
+ Q+ G++ +E +LAQ R E ++Q QEY+ LL++K +LE EIATYRRLLE GED +L
Sbjct: 339 LSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLE-GEDAHLTQ 397
Query: 395 ALDSSNSMQTIQKTTTRRIVDGKVVS 420
+ + + +T + DGKV+S
Sbjct: 398 YKKEPVTTRQV-RTIVEEVQDGKVIS 422
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 324 bits (831), Expect = 8e-89
Identities = 182/385 (47%), Positives = 255/385 (66%), Gaps = 10/385 (2%)
Query: 10 STNYRSLGSVQAPSY-GARPVSSAASVYAGAGGSGS--RISVSRSTSFRGGMGSGGLATG 66
S Y LG S+ G+ SS Y G+ G GS S + GG G GG G
Sbjct: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGG 130
Query: 67 IAGGLAGMGGIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP--- 121
GG G GG+ NEK TMQ+LNDRLASYLD+VR+LE N LE KI+E EK G
Sbjct: 131 FGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQ 190
Query: 122 -QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180
+ RD+S Y+K I+DL+ QI T DNA I+LQIDNARLAADDFR+KYE E+A+RQSVE
Sbjct: 191 GEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEA 250
Query: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240
DI+GLR+V+D+ +T+ LE +IE+L EEL ++KKNHEEE+K L+ +++ + VE++A
Sbjct: 251 DINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLR-NVSTGDVNVEMNAA 309
Query: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300
DL +++ ++R+QY++LA +NR++ + +++++ +E TT + ++ + ++ +TELR
Sbjct: 310 PGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELR 369
Query: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360
R VQ+LEI+L S LK SLE SL E E RY +Q+ Q+ + LE +L Q RAE + Q
Sbjct: 370 RNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQN 429
Query: 361 QEYEALLNIKVKLEAEIATYRRLLE 385
EY+ LL+IK++LE EI TYR LLE
Sbjct: 430 TEYQQLLDIKIRLENEIQTYRSLLE 454
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 323 bits (827), Expect = 2e-88
Identities = 190/417 (45%), Positives = 270/417 (64%), Gaps = 25/417 (5%)
Query: 7 STFSTNYRSLGSVQAPSYGARPVSSAASVYAG-AGGSGSRISVSRSTSFRGGMGSGGLAT 65
ST ST + S GS A YG V G GG+GS GG G GGL
Sbjct: 30 STCSTRFVSGGS--AGGYGG-------GVSCGFGGGAGSGFGGGYGGGLGGGYG-GGLGG 79
Query: 66 GIAGGLAGM--------GGIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREH 115
G GG AG GG+ NEK TMQ+LNDRLASYL++VR+LE N LE KIR+
Sbjct: 80 GFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDW 139
Query: 116 LEKKGPQV--RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELA 173
K+ P RD+S Y+K IE+LR +I T++N R++L+IDNARLAADDFR+KYE ELA
Sbjct: 140 HLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELA 199
Query: 174 MRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGL 233
+RQSVE DI+GLR+V+D+ +++ LE +IE+L EEL +MKKNHEEE+K Q+ +
Sbjct: 200 LRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQ-V 258
Query: 234 TVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAE 293
VE+DA DL +++A++R QY+ +A +NR + ++++ + E V+T +A + ++
Sbjct: 259 NVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSK 318
Query: 294 TTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTR 353
T +TELRRT+Q LEI+L S ++KA LEN++ E E RYALQ++Q+ G++ +E++L++ R
Sbjct: 319 TEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELR 378
Query: 354 AEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTT 410
+E + Q QEY+ LL+IK +LE EIATYR LLE G+D + S+ S+ + T
Sbjct: 379 SEMECQNQEYKMLLDIKTRLEQEIATYRSLLE-GQDAKMIGFPSSAGSVSPRSTSVT 434
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 322 bits (826), Expect = 3e-88
Identities = 187/396 (47%), Positives = 263/396 (66%), Gaps = 25/396 (6%)
Query: 7 STFSTNYRSLGSVQAPSYGARPVSSAASVYAG-AGGSGSRISVSRSTSFRGGMGSGGLAT 65
ST ST + S GS A YG V G GG+GS GG G GGL
Sbjct: 30 STCSTRFVSGGS--AGGYGG-------GVSCGFGGGAGSGFGGGYGGGLGGGYG-GGLGG 79
Query: 66 GIAGGLAGM--------GGIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREH 115
G GG AG GG+ NEK TMQ+LNDRLASYL++VR+LE N LE KIR+
Sbjct: 80 GFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDW 139
Query: 116 LEKKGPQV--RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELA 173
K+ P RD+S Y+K IE+LR +I T++N R++L+IDNARLAADDFR+KYE ELA
Sbjct: 140 HLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELA 199
Query: 174 MRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGL 233
+RQSVE DI+GLR+V+D+ +++ LE +IE+L EEL +MKKNHEEE+K Q+ +
Sbjct: 200 LRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQ-V 258
Query: 234 TVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAE 293
VE+DA DL +++A++R QY+ +A +NR + ++++ + E V+T +A + ++
Sbjct: 259 NVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSK 318
Query: 294 TTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTR 353
T +TELRRT+Q LEI+L S ++KA LEN++ E E RYALQ++Q+ G++ +E++L++ R
Sbjct: 319 TEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELR 378
Query: 354 AEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGED 389
+E + Q QEY+ LL+IK +LE EIATYR LLE G+D
Sbjct: 379 SEMECQNQEYKMLLDIKTRLEQEIATYRSLLE-GQD 413
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 313 bits (801), Expect = 2e-85
Identities = 181/388 (46%), Positives = 258/388 (66%), Gaps = 18/388 (4%)
Query: 11 TNYRSLGSVQAPSYG--ARPVSSAASVYAGAGGS--GSRISVSRSTSFRGGMGSGG-LAT 65
++ RS+GS + PS A +SSA S +G G GS +S TS G +GSGG
Sbjct: 29 SSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTS--GFVGSGGWFCE 86
Query: 66 GIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-R 124
G G +EKETMQ LNDRLA+YL++VR LE EN LES+I+E E + P +
Sbjct: 87 GSFNG--------SEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICP 138
Query: 125 DWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHG 184
D+ YFK IED + +I +NAR+VLQIDNA+LAADDFR KYETEL++RQ VE DI+G
Sbjct: 139 DYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADING 198
Query: 185 LRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQD 244
LR+++D+ + + LE ++E+LKEEL+ +KKNHEEEV L+ Q+ L VEVDA D
Sbjct: 199 LRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDR-LNVEVDAAPPVD 257
Query: 245 LAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQ 304
L KI+ D+R QY+ L NR +++ +++ Q EE V + S ++ +T + ELRRTV
Sbjct: 258 LNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVN 317
Query: 305 SLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYE 364
+LEI+L + +++ SLE++L E EARY+ Q+ Q+ ++ ++E++L++ R + +RQ QEY+
Sbjct: 318 ALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQ 377
Query: 365 ALLNIKVKLEAEIATYRRLLEDGEDFNL 392
LL++K +LE EIATYR LLE GED L
Sbjct: 378 VLLDVKARLEGEIATYRHLLE-GEDCKL 404
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 312 bits (799), Expect = 4e-85
Identities = 191/444 (43%), Positives = 264/444 (59%), Gaps = 40/444 (9%)
Query: 15 SLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIA-GGLAG 73
S+G + G+ S + G G G S+ F G G + G GG G
Sbjct: 72 SVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVG 131
Query: 74 MGGIQN--EKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP------QVRD 125
GG+ + EK+TMQ+LNDRLA+YLD+VR+LE N LE+KI+E +K GP RD
Sbjct: 132 DGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRD 191
Query: 126 WSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGL 185
+S Y+ IIEDLR QI A TV+NA I+L IDNARLAADDFR+KYE EL +RQSVE DI+GL
Sbjct: 192 YSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGL 251
Query: 186 RKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDL 245
RKV+DD +TR LE +IE+ EEL +++KNHEEE+K +Q + +TVE++A DL
Sbjct: 252 RKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGS-SGGEVTVEMNAAPGTDL 310
Query: 246 AKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQS 305
K++ D+RAQY+ELA +NR E ++ +++Q ++T + +A+ +TEL+RT+Q+
Sbjct: 311 TKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQA 370
Query: 306 LEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEA 365
LEI+L S +K+SLE +L + EA Y Q+ ++ + LE E+ Q E + Q EY+
Sbjct: 371 LEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQ 430
Query: 366 LLNIKVKLEAEIATYRRLLEDGE----------------------DFNLGDALDSS---- 399
LL+IK +LE EI TYRRLL DGE D GD+ S
Sbjct: 431 LLDIKTRLEVEIETYRRLL-DGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQ 489
Query: 400 ---NSMQTIQKTTTRRIVDGKVVS 420
+S + KT +VDGKVVS
Sbjct: 490 GRDSSKTRVTKTIVEELVDGKVVS 513
Score = 30.0 bits (66), Expect = 4.2
Identities = 21/51 (41%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Query: 30 SSAASVYAGAGG--SGSRISVSRSTS--FRGGMGSGGLATGIAGGLAGMGG 76
SS+A V AG SGSR + S++ FRGG S L+ G +G G G
Sbjct: 15 SSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFG 65
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 308 bits (790), Expect = 5e-84
Identities = 188/426 (44%), Positives = 263/426 (61%), Gaps = 18/426 (4%)
Query: 1 MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS 60
M F+ RS + SL + + G + + + SVY GAGG G RIS SR T G +
Sbjct: 1 MDFSRRSFHRSLSSSLQAPVVSTVGMQRLGTTPSVYGGAGGRGIRISNSRHTVNYGSDLT 60
Query: 61 GGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKG 120
GG G + NEK MQ+LNDRLASYL++VR+LE N +LE +I++ E
Sbjct: 61 GG----------GDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNA 110
Query: 121 PQV-RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVE 179
P+ RD+S Y++ IE+LR+QI + NAR VLQIDNA+LAA+DFR+KYETE +R +VE
Sbjct: 111 PRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVE 170
Query: 180 NDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDA 239
D+ GL KV DD + + LE +IE L ++L +KK H+EEV GL + ++ + VEVDA
Sbjct: 171 ADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNT-VNVEVDA 229
Query: 240 PKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTEL 299
+L IM ++R +Y+ +A+KN +E + + +Q VT + E+ E LTEL
Sbjct: 230 APGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTEL 289
Query: 300 RRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQ 359
RRT QSLEI+L S ++K SLE++L E +ARY+ Q+ L +L LE++L Q R+ +RQ
Sbjct: 290 RRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQ 349
Query: 360 AQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQ-----KTTTRRIV 414
EY LL+IK +LE EIATYRRLLE GED + S+ + I+ KT + +V
Sbjct: 350 NNEYHILLDIKTRLEQEIATYRRLLE-GEDVKTTEYQLSTLEERDIKKTRKIKTVVQEVV 408
Query: 415 DGKVVS 420
DGKVVS
Sbjct: 409 DGKVVS 414
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 303 bits (775), Expect = 3e-82
Identities = 181/431 (41%), Positives = 271/431 (62%), Gaps = 45/431 (10%)
Query: 31 SAASVYAGA----GGSGSRISVSRSTSFR---GGMGSGGLATGIAGGLAGM--------- 74
SAAS++ + GGSGS ++ + GG GGL G G G
Sbjct: 58 SAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGND 117
Query: 75 GGIQN--EKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRD-----WS 127
GG+ + EKETMQ+LNDRLASYLD+VR+LE N LE+KIRE E +G D +S
Sbjct: 118 GGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYS 177
Query: 128 HYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRK 187
Y+ +IEDLR +I + ++ NA+++LQIDNARLAA+DFR+KYE ELA+RQ VE DI+GLR+
Sbjct: 178 KYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRR 237
Query: 188 VIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAK 247
V+D+ +TR LE +IE+L EEL +MKKNHE+E++ + ++VE+DA DL +
Sbjct: 238 VLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVG-GPGEVSVEMDAAPGVDLTR 296
Query: 248 IMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLE 307
++ D+RAQY+ +A +NR++ + ++ ++ E ++T + ++ ++++ +T+LRR Q+LE
Sbjct: 297 LLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLE 356
Query: 308 IDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALL 367
I+L S +K SLE+SL E E Y Q+ Q+ ++ +LE++L Q RA+ +RQ +++ LL
Sbjct: 357 IELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLL 416
Query: 368 NIKVKLEAEIATYRRLLEDGEDFNLGDAL-------DSSNSMQTIQ-----------KTT 409
N+K +LE EI TYRRLL DGE GD L DS + Q+ KT
Sbjct: 417 NVKARLELEIETYRRLL-DGE--AQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTV 473
Query: 410 TRRIVDGKVVS 420
+ +V+G+VVS
Sbjct: 474 VQEMVNGEVVS 484
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 299 bits (765), Expect = 4e-81
Identities = 159/337 (47%), Positives = 235/337 (69%), Gaps = 6/337 (1%)
Query: 60 SGGLATGIAGGLAGMG-GIQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHL 116
+GG AT +GG G GI NEKETMQSLNDRLA YL++VR LE EN LES+IRE
Sbjct: 74 AGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEKVRQLEQENASLESRIREWC 133
Query: 117 EKKGPQV-RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMR 175
E++ P + D+ YF+ IE+L+ + + +NAR+V++IDNA+LAADDFR KYETE+++R
Sbjct: 134 EQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFRTKYETEVSLR 193
Query: 176 QSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTV 235
Q VE+DI+GLR+++DD + + LE ++E+LKEELL +KKNHEEEV L+ Q+ L V
Sbjct: 194 QLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLRCQLGDR-LNV 252
Query: 236 EVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETT 295
EVDA DL +++ ++R QY+ L NR + + + Q EE V + S ++ + +
Sbjct: 253 EVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSSEQLQSCQAE 312
Query: 296 LTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAE 355
+ ELRRTV +LEI+L + +++ +LE++L E EARY+ Q+ Q+ ++ ++E++LA+ RA+
Sbjct: 313 IIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVEAQLAEIRAD 372
Query: 356 GQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNL 392
+RQ QEY+ LL+++ +LE EI TYR LLE ED L
Sbjct: 373 LERQNQEYQVLLDVRARLECEINTYRGLLE-SEDSKL 408
>gi|27734744 hypothetical protein LOC284085 [Homo sapiens]
Length = 259
Score = 298 bits (764), Expect = 5e-81
Identities = 160/199 (80%), Positives = 174/199 (87%), Gaps = 2/199 (1%)
Query: 26 ARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQ 85
A+ VSS ASVYAG GSGSRIS+S TSF+G MGS GL +AGGLAGMG IQNEKETMQ
Sbjct: 63 AQLVSSVASVYAGIRGSGSRISMSCFTSFQGSMGSRGLPAVMAGGLAGMGVIQNEKETMQ 122
Query: 86 SLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTV 145
SLND LASYLDRVRSL+T+N +LES+ EHLEKKGPQVRDWSH FK IE+LRAQIFANTV
Sbjct: 123 SLNDHLASYLDRVRSLDTKNWKLESQ--EHLEKKGPQVRDWSHDFKTIENLRAQIFANTV 180
Query: 146 DNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEA 205
D+A IVLQIDNA LA DDFRVKYETELAM QSVE+DIHGL KVIDDTN+T LQLE EI+A
Sbjct: 181 DSAHIVLQIDNACLAGDDFRVKYETELAMCQSVESDIHGLHKVIDDTNVTWLQLEAEIKA 240
Query: 206 LKEELLFMKKNHEEEVKGL 224
LKE+LLFMKKNHEEEVKGL
Sbjct: 241 LKEKLLFMKKNHEEEVKGL 259
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 293 bits (751), Expect = 2e-79
Identities = 152/315 (48%), Positives = 228/315 (72%), Gaps = 3/315 (0%)
Query: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
+EKETMQ LNDRLASYL++VR LE +N LE+ IRE +++ P V + YFK IE+L+
Sbjct: 55 SEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQ 114
Query: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
+I + +NAR+V+QIDNA+LA+DDFR KYETEL++RQ VE+DI+GLR+++D+ + R
Sbjct: 115 QKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRS 174
Query: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
LE ++E+LKEELL +K+NHE+EV L+ Q+ L VEVDA + DL +++ + R+QY+
Sbjct: 175 DLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNQVLNETRSQYE 233
Query: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
L NR E++++++ Q EE V + S ++ + + + ELRRTV +LEI+L + NL+
Sbjct: 234 ALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
Query: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
SLEN+L E EARY+ Q+ Q+ ++ ++ES+LA+ R++ +RQ QEY+ LL+++ +LE EI
Sbjct: 294 DSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
Query: 378 ATYRRLLEDGEDFNL 392
TYR LLE ED L
Sbjct: 354 NTYRSLLE-SEDCKL 367
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 293 bits (751), Expect = 2e-79
Identities = 151/315 (47%), Positives = 227/315 (72%), Gaps = 3/315 (0%)
Query: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
+EKETMQ LNDRLASYL++VR LE +N LE+ IRE +++ P + + YFK IE+L+
Sbjct: 55 SEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQ 114
Query: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
+I +NAR+V+QIDNA+LAADDFR KY+TEL++RQ VE+DI+GLR+++D+ + +
Sbjct: 115 QKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKS 174
Query: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
LE ++E+LKEELL +K NHE+EV L+ Q+ L VEVDA + DL +++ + R+QY+
Sbjct: 175 DLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRSQYE 233
Query: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
L NR E++++++ Q EE V + S ++ + + + ELRRTV +LEI+L + NL+
Sbjct: 234 ALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
Query: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
SLEN+L E EARY+ Q+ Q+ ++ ++ES+LA+ R++ +RQ QEY+ LL+++ +LE EI
Sbjct: 294 DSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
Query: 378 ATYRRLLEDGEDFNL 392
TYR LLE ED NL
Sbjct: 354 NTYRSLLE-SEDCNL 367
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 291 bits (745), Expect = 8e-79
Identities = 161/367 (43%), Positives = 238/367 (64%), Gaps = 17/367 (4%)
Query: 27 RPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQS 86
RP S + Y + S ++ G MG G + G G NEKETMQ
Sbjct: 57 RPASCLSKTYLSS-------SCQAASGISGSMGPGSWYS--EGAFNG-----NEKETMQF 102
Query: 87 LNDRLASYLDRVRSLETENRRLESKIREHLEKKG-PQVRDWSHYFKIIEDLRAQIFANTV 145
LNDRLASYL RVR LE EN LES+I+E + D+ +F+ IE+L+ +I
Sbjct: 103 LNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKA 162
Query: 146 DNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEA 205
+NAR+V+ IDNA+LAADDFR KYE ELAMRQ VE DI+GLR+++DD + + LE ++E+
Sbjct: 163 ENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVES 222
Query: 206 LKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNRE 265
LKEEL+ +KKNHEEEV L+ Q+ L +EVDA DL +++ ++R QY+ + NR
Sbjct: 223 LKEELMCLKKNHEEEVGSLRCQLGDR-LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRR 281
Query: 266 ELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLR 325
+++++++ Q+EE V T S ++ ++ + +LRRTV +LEI+L + +L+ SLEN+L
Sbjct: 282 DVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLT 341
Query: 326 EVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLE 385
E EARY+ Q+ Q+ ++ ++E++LA+ RA+ +RQ QEY+ LL+++ +LE EI TYR LLE
Sbjct: 342 ESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLE 401
Query: 386 DGEDFNL 392
+ ED L
Sbjct: 402 N-EDCKL 407
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 286 bits (732), Expect = 3e-77
Identities = 149/315 (47%), Positives = 225/315 (71%), Gaps = 3/315 (0%)
Query: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
+EKETMQ LNDRLASYL++VR LE +N LE+ IRE +++ P + + YFK IE+L+
Sbjct: 55 SEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQ 114
Query: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
+I + +NAR+V+QIDNA+LAADDFR KY+TE ++RQ VE+DI+ LR+++D+ + R
Sbjct: 115 QKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRS 174
Query: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
LE ++E+LKEELL +K+NHE+EV L+ Q+ L VEVDA + DL +++ + R QY+
Sbjct: 175 DLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDR-LNVEVDAAPAVDLNQVLNETRNQYE 233
Query: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
L NR E++++++ Q EE V + S ++ + + + ELRRTV +LEI+L + NL+
Sbjct: 234 ALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
Query: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
SLEN+L E EARY+ Q+ Q+ ++ ++ES+LA+ R++ +RQ QEY+ LL+++ +LE EI
Sbjct: 294 YSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
Query: 378 ATYRRLLEDGEDFNL 392
TYR LLE ED L
Sbjct: 354 NTYRSLLE-SEDCKL 367
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 284 bits (727), Expect = 1e-76
Identities = 178/421 (42%), Positives = 251/421 (59%), Gaps = 29/421 (6%)
Query: 27 RPVSSAASVYAGAGGSGSRISVSR-STSFRGGMGS--------GGLATGIAGGLAGM-GG 76
RP++ A +AG+ G ++ S S + GG+GS G L G AG GG
Sbjct: 22 RPLNGGAG-FAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEGG 80
Query: 77 IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129
+ NEK TMQ+LNDRLASYLD VR+LE N LE KI+ EK GP D+S Y
Sbjct: 81 LLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSRY 140
Query: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189
IEDL+ +I ++T NA ++LQIDNARLAADDFR+KYE EL + Q+VE DI+GLR+V+
Sbjct: 141 HLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVL 200
Query: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249
D+ + R E + E+L EE+ ++KKNHEEE+K LQ A + VE++A DLA ++
Sbjct: 201 DELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQC-AAGGNVNVEMNAAPGVDLAVLL 259
Query: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEID 309
++RA+Y+ LA +NR++ + +++++ ++ S A + LTE+RRT+Q+LEI
Sbjct: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319
Query: 310 LDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNI 369
L S+ K SLE SL E E+ Y Q+ Q+ + LE +L Q R E + Q EYE LL++
Sbjct: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379
Query: 370 KVKLEAEIATYRRLLE-DGEDFNLGDALDS---SNSMQTIQKTTTRRIV------DGKVV 419
KV LE EI TY RL++ DG + S NS + + KTT + V GKV+
Sbjct: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFGSGSPGNSSKDLSKTTLVKTVVEELDQRGKVL 439
Query: 420 S 420
S
Sbjct: 440 S 440
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 281 bits (718), Expect = 1e-75
Identities = 184/448 (41%), Positives = 249/448 (55%), Gaps = 32/448 (7%)
Query: 9 FSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIA 68
FS+ R LGS R S A AG I S +F G +GG G+
Sbjct: 5 FSSTSRRLGSCGGTG-SVRLSSGGAGFGAGNTCGVPGIGSGFSCAFGGSSSAGGYGGGLG 63
Query: 69 GGLAGMGGIQ---------NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKK 119
GG A NEK TMQ+LNDRLASYL+ VR+LE N LE KI+ EK
Sbjct: 64 GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKF 123
Query: 120 GPQV-----RDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAM 174
GP D+S YF II++L+ QI + T NA +VLQ DNARL ADDFR+K+E ELA+
Sbjct: 124 GPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
Query: 175 RQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLT 234
QSVE DI+GLR+V+D+ + R LE ++E L EEL ++KKNHEEE+K LQ A +
Sbjct: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQC-AAGGNVN 242
Query: 235 VEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAET 294
VE++A DL ++ ++RA+Y+ LA +NR + + +++++ ++ + +A
Sbjct: 243 VEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARN 302
Query: 295 TLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRA 354
L E++RT+Q+LEI+L S+ K SLE SL E E+ Y Q+ Q+ + LE +L Q R
Sbjct: 303 ELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRT 362
Query: 355 EGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDA--------LDSSNSMQTIQ 406
E + Q EYE LL+IKV LE EI TY LL DGED + + +S TI
Sbjct: 363 ETEGQKLEYEQLLDIKVHLEKEIETY-CLLIDGEDGSCSKSKGYGGPGNQTKDSSKTTIV 421
Query: 407 KTTTRRI-VDGKVVS------ETNDTKV 427
KT I GKV+S E TKV
Sbjct: 422 KTVVEEIDPRGKVLSSRVHTVEEKSTKV 449
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 275 bits (703), Expect = 6e-74
Identities = 141/315 (44%), Positives = 221/315 (70%), Gaps = 3/315 (0%)
Query: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
+EKETMQ LNDRLASYL++VR LE +N LE I+E +++ P + + YFK IE+L+
Sbjct: 97 SEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQ 156
Query: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
+I +NAR+V+ IDNA+LA+DDFR KY+TE ++R VE+DI+ +R+++D+ + +
Sbjct: 157 QKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKS 216
Query: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
LE+++E+L+EEL+ +KKNHEEEV L++Q+ L VEVD + DL +++ + R+QY+
Sbjct: 217 DLESQVESLREELICLKKNHEEEVNTLRSQLGDR-LNVEVDTAPTVDLNQVLNETRSQYE 275
Query: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
L NR E++++++ Q EE V + S ++ + + + ELRRTV +LEI+L + NL+
Sbjct: 276 ALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLR 335
Query: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
SLEN+L E EA Y+ Q+ Q+ ++ ++ES+LA+ R + +RQ QEY+ LL+++ +LE EI
Sbjct: 336 DSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEI 395
Query: 378 ATYRRLLEDGEDFNL 392
TYR LLE ED L
Sbjct: 396 NTYRSLLE-SEDCKL 409
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 270 bits (691), Expect = 1e-72
Identities = 171/383 (44%), Positives = 236/383 (61%), Gaps = 26/383 (6%)
Query: 27 RPVSSAASVYAGAG--GSGSRISVSR-----STSFRGGMGSGGLATG---IAGGLAGMGG 76
RP + + +Y G G+G+ +S S++F GG SGG G AG G
Sbjct: 15 RPTTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAF-GGSSSGGNTGGGNPCAGFTVNERG 73
Query: 77 IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-----RDWSHY 129
+ NEK TMQ+LNDRLASYLD V +LE N LE KI+ EK GP D+S Y
Sbjct: 74 LLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRY 133
Query: 130 FKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVI 189
F II+DL+ QI A+T NA VLQIDNARL ADDFR+KYE ELA+ QSVE D++GLR+V+
Sbjct: 134 FPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVL 193
Query: 190 DDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIM 249
D+ + R LE + E L EE+ ++KKNH+EE++ LQ A + VE++A DL ++
Sbjct: 194 DEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQC-AAGGNVNVEMNAAPGVDLTVLL 252
Query: 250 ADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGA---AETTLTELRRTVQSL 306
++RA+Y+ LA +NR + + +++ E+S ++ S +VGA A LTE++RT+Q+L
Sbjct: 253 NNMRAEYEALAEQNRRDAEAWFN---EKSASLQQQISEDVGATTSARNELTEMKRTLQTL 309
Query: 307 EIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEAL 366
EI+L S+ K SLE SL E E+ Y Q+ Q+ + LE +L Q R E + Q EYE L
Sbjct: 310 EIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQL 369
Query: 367 LNIKVKLEAEIATYRRLLEDGED 389
L+IK+ LE EI TY LL G+D
Sbjct: 370 LDIKLHLEKEIETY-CLLIGGDD 391
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 270 bits (690), Expect = 2e-72
Identities = 155/367 (42%), Positives = 227/367 (61%), Gaps = 8/367 (2%)
Query: 36 YAGAGGSGSRISVSRSTSFRGGMGSG-GLATGIAGGLAGM-GGI--QNEKETMQSLNDRL 91
Y+ +GG G F GG GSG G G GG G GGI NEK TMQ LN RL
Sbjct: 105 YSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRL 164
Query: 92 ASYLDRVRSLETENRRLESKIREHLEKKGPQV--RDWSHYFKIIEDLRAQIFANTVDNAR 149
ASYLD+V++LE N LE+KI++ +KKGP +++S Y+ I+DL+ QI TV N +
Sbjct: 165 ASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNK 224
Query: 150 IVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEE 209
+L IDN R+ DDFR+K+E E +RQ V+ DI+GLR+V+D+ + + LE + E L+EE
Sbjct: 225 TLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEE 284
Query: 210 LLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDK 269
L+ +KKNH+EE+ L Q S + VE++ +DL K + D+R +Y++L KNR++++
Sbjct: 285 LMALKKNHKEEMSQLTGQ-NSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKDIEN 343
Query: 270 YWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEA 329
+ QI + V++ EV ++ +T+LR VQ LEI+L S + KA+LE SL + +
Sbjct: 344 QYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLEDTKN 403
Query: 330 RYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDG-E 388
RY Q++ + + +LE+++ R E + Q QEY LL+IK++LE EI TY LLE G E
Sbjct: 404 RYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEGGQE 463
Query: 389 DFNLGDA 395
DF A
Sbjct: 464 DFESSGA 470
Score = 30.8 bits (68), Expect = 2.5
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 5/58 (8%)
Query: 23 SYGARPVSSAASVYAGAG-----GSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMG 75
SYG + Y G G G GS S+ GG GSGG + G GG +G G
Sbjct: 484 SYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG 541
Score = 29.6 bits (65), Expect = 5.5
Identities = 18/39 (46%), Positives = 20/39 (51%)
Query: 38 GAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGG 76
G+GGS R S S GG GSGG G +G G GG
Sbjct: 480 GSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518
Score = 29.3 bits (64), Expect = 7.2
Identities = 16/38 (42%), Positives = 21/38 (55%)
Query: 39 AGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGG 76
+GGSG S ++ GG GSGG + G GG +G G
Sbjct: 543 SGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRG 580
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 261 bits (666), Expect = 1e-69
Identities = 135/317 (42%), Positives = 209/317 (65%), Gaps = 2/317 (0%)
Query: 73 GMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFK 131
G G NEKETMQ LN+RLA+YL +VR LE EN LESKI+E K+ P + D+ Y+
Sbjct: 89 GEGINSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYT 148
Query: 132 IIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDD 191
IE+L+ +I +N+R+V QIDN +L ADD R KYE E+++RQ VE+D +GL+++++
Sbjct: 149 TIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNV 208
Query: 192 TNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMAD 251
+ + LE ++++LKEELL +K NH+EE+ LQ Q+ L +EV A S DL +++ +
Sbjct: 209 LTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGER-LDIEVTAAPSADLNQVLQE 267
Query: 252 IRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLD 311
+R QY+ + NR++++++++ QIEE V T S + + + ELRR+V +LE++L
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327
Query: 312 SMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKV 371
+ ++ S E L E EARY + Q+ ++ +LE++LA+ R +RQ QEYE LL++K
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387
Query: 372 KLEAEIATYRRLLEDGE 388
+LE EI TYR LLE +
Sbjct: 388 RLECEITTYRSLLESSD 404
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 259 bits (661), Expect = 4e-69
Identities = 157/364 (43%), Positives = 219/364 (60%), Gaps = 19/364 (5%)
Query: 41 GSGSRISVSRSTSFRGGMGS-----GGLATGIAGGLAG-----MGGIQNEKETMQSLNDR 90
GSG+R S S + GS GGL +G G G + G NEK TMQ+LNDR
Sbjct: 36 GSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSG--NEKVTMQNLNDR 93
Query: 91 LASYLDRVRSLETENRRLESKIREHLEKKGP-----QVRDWSHYFKIIEDLRAQIFANTV 145
LASYLD V +LE N LE KI+ EK P D+S YF +IEDL+ QI + T+
Sbjct: 94 LASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATI 153
Query: 146 DNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEA 205
NA IVLQ DNARL ADDFR+KYE ELA+ SVE D GLR+V+D+ + LE + E
Sbjct: 154 CNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCET 213
Query: 206 LKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNRE 265
L EEL ++KK+HEEE++ LQ A + VE++A DL ++ ++RA+Y++LA +NR+
Sbjct: 214 LSEELTYLKKSHEEEMEVLQ-YTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRK 272
Query: 266 ELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLR 325
+ + +++++ ++ AA LTEL+R +Q+LEI+L S+ +K S E SL
Sbjct: 273 DAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLA 332
Query: 326 EVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLE 385
E E Y Q++Q+ + +E +L Q R E + Q EYE LL++K+ LE EI Y LL
Sbjct: 333 ETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLL- 391
Query: 386 DGED 389
DGE+
Sbjct: 392 DGEE 395
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 255 bits (651), Expect = 6e-68
Identities = 152/401 (37%), Positives = 241/401 (60%), Gaps = 23/401 (5%)
Query: 27 RPVSSAASVYAGAGGSGSRISVS---RSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKET 83
R A +V+ GAGG+ RIS+S RS GG G ++ + GG N K T
Sbjct: 26 RSFPRAPTVHGGAGGA--RISLSFTTRSCPPPGGSWGSGRSSPLLGG--------NGKAT 75
Query: 84 MQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP-QVRDWSHYFKIIEDLRAQIFA 142
MQ+LNDRLASYL++VR+LE N +LES+I + +++ P +D+S Y + I L+ QI
Sbjct: 76 MQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVD 135
Query: 143 NTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETE 202
+ NA+I+L IDNAR+A DDF +KYE E + ++ +E ++ GLR+ +D+ I LE E
Sbjct: 136 GKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQE 195
Query: 203 IEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARK 262
+E +++EL+ MKK+HE+E++ + + V+VD +DL K++ D+R +Y+ + +K
Sbjct: 196 VEGMRKELILMKKHHEQEMEKHHVP-SDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKK 254
Query: 263 NREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLEN 322
+LD ++ +Q + + A V + + + EL+RT Q+LEIDL + + K++LEN
Sbjct: 255 KHRDLDTWYKEQ-SAAMSQEAASPATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALEN 313
Query: 323 SLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRR 382
L E ++RY+ +++ + I+ H E EL Q R E +RQ EY+ LL IK LE EI TYRR
Sbjct: 314 MLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRR 373
Query: 383 LLEDGEDFNLGDALDSSNSMQTIQ----KTTTRRIVDGKVV 419
LLE + G +S +SM+ K T+ ++G++V
Sbjct: 374 LLEGESE---GTREESKSSMKVSATPKIKAITQETINGRLV 411
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 252 bits (644), Expect = 4e-67
Identities = 134/315 (42%), Positives = 209/315 (66%), Gaps = 3/315 (0%)
Query: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
NEKETMQ LNDRLASYL++VRSLE N LES+I+E E+ P V D+ YF IEDL+
Sbjct: 88 NEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQ 147
Query: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
+I +N+R+ +Q+DN +LA DDF+ KYE+EL++RQ +E DI L ++++ + +
Sbjct: 148 QKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKS 207
Query: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
LE +E+LKE+LL +KKNHEEEV L+ Q+ L+VE+D + DL +++ ++R Q +
Sbjct: 208 DLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDR-LSVELDTAPTLDLNRVLDEMRCQCE 266
Query: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
+ NR E +++ + Q EE + + ++ + + EL+RT +LEI+L + ++L
Sbjct: 267 TVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLT 326
Query: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
SLE ++ E EA+Y+ Q+ Q+ ++ +LE++LA+ R + +RQ QEY+ LL++K +LE EI
Sbjct: 327 ESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEI 386
Query: 378 ATYRRLLEDGEDFNL 392
TY LL D ED L
Sbjct: 387 NTYWGLL-DSEDSRL 400
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 250 bits (639), Expect = 2e-66
Identities = 133/315 (42%), Positives = 211/315 (66%), Gaps = 3/315 (0%)
Query: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
+EKETMQ LNDRLA+YL++VR LE EN LE+ + E + V D+ YF IE+L+
Sbjct: 103 HEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQ 162
Query: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
+I + +NAR+++QIDNA+LAADDFR+K E+E ++RQ VE D G +K++DD + +
Sbjct: 163 QKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKA 222
Query: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
LE + E+LKEE L +K NHE+EVK L++Q+ L +E+D + DL +++ ++RAQY+
Sbjct: 223 DLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEK-LRIELDIEPTIDLNRVLGEMRAQYE 281
Query: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
+ NR+++++++ Q E + + S E+ ++ + ELR TV +LE++ + LK
Sbjct: 282 AMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLK 341
Query: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
L+NSL E E R+ ++ Q+ ++ ++E +L++ RA+ +RQ QEY+ LL++K +LE EI
Sbjct: 342 DCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEI 401
Query: 378 ATYRRLLEDGEDFNL 392
ATYR LLE ED L
Sbjct: 402 ATYRNLLE-SEDCKL 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,686,649
Number of Sequences: 37866
Number of extensions: 525287
Number of successful extensions: 5488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 175
Number of HSP's successfully gapped in prelim test: 550
Number of HSP's that attempted gapping in prelim test: 3411
Number of HSP's gapped (non-prelim): 1869
length of query: 430
length of database: 18,247,518
effective HSP length: 105
effective length of query: 325
effective length of database: 14,271,588
effective search space: 4638266100
effective search space used: 4638266100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.