Guide to the Human Genome
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Search of human proteins with 4507391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507391 transcription factor 12 isoform b [Homo sapiens]
         (682 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46370084 transcription factor 12 isoform b [Homo sapiens]         1370   0.0  
gi|4507391 transcription factor 12 isoform b [Homo sapiens]          1370   0.0  
gi|46370082 transcription factor 12 isoform a [Homo sapiens]         1357   0.0  
gi|46370080 transcription factor 12 isoform a [Homo sapiens]         1357   0.0  
gi|46370086 transcription factor 12 isoform c [Homo sapiens]          983   0.0  
gi|145312267 transcription factor 4 isoform a [Homo sapiens]          809   0.0  
gi|4507399 transcription factor 4 isoform b [Homo sapiens]            803   0.0  
gi|27777636 transcription factor 3 isoform E12 [Homo sapiens]         597   e-170
gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]        581   e-166
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    72   2e-12
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        67   4e-11
gi|151301154 mucin 6, gastric [Homo sapiens]                           58   3e-08
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    55   2e-07
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        54   6e-07
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             53   1e-06
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    52   2e-06
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    50   7e-06
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    50   9e-06
gi|57864582 hornerin [Homo sapiens]                                    49   1e-05
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  47   6e-05
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           46   1e-04
gi|54860079 nadrin isoform 1 [Homo sapiens]                            45   2e-04
gi|118498337 HECT domain containing 1 [Homo sapiens]                   45   2e-04
gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap...    45   2e-04
gi|47716512 mex-3 homolog B [Homo sapiens]                             45   2e-04
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]            45   3e-04
gi|83367077 mucin 16 [Homo sapiens]                                    44   5e-04
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             44   5e-04
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             44   5e-04
gi|60097902 filaggrin [Homo sapiens]                                   44   6e-04

>gi|46370084 transcription factor 12 isoform b [Homo sapiens]
          Length = 682

 Score = 1370 bits (3546), Expect = 0.0
 Identities = 682/682 (100%), Positives = 682/682 (100%)

Query: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60
           MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW
Sbjct: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60

Query: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120
           GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY
Sbjct: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120

Query: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180
           SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA
Sbjct: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180

Query: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240
           KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS
Sbjct: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240

Query: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300
           SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG
Sbjct: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300

Query: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360
           STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP
Sbjct: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360

Query: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVG 420
           STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVG
Sbjct: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVG 420

Query: 421 PSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNH 480
           PSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNH
Sbjct: 421 PSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNH 480

Query: 481 SVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKS 540
           SVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKS
Sbjct: 481 SVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKS 540

Query: 541 DDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKEL 600
           DDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKEL
Sbjct: 541 DDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKEL 600

Query: 601 GRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAE 660
           GRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAE
Sbjct: 601 GRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAE 660

Query: 661 PPTTLPGTHPGLSETTNPMGHM 682
           PPTTLPGTHPGLSETTNPMGHM
Sbjct: 661 PPTTLPGTHPGLSETTNPMGHM 682


>gi|4507391 transcription factor 12 isoform b [Homo sapiens]
          Length = 682

 Score = 1370 bits (3546), Expect = 0.0
 Identities = 682/682 (100%), Positives = 682/682 (100%)

Query: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60
           MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW
Sbjct: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60

Query: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120
           GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY
Sbjct: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120

Query: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180
           SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA
Sbjct: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180

Query: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240
           KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS
Sbjct: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240

Query: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300
           SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG
Sbjct: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300

Query: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360
           STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP
Sbjct: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360

Query: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVG 420
           STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVG
Sbjct: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVG 420

Query: 421 PSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNH 480
           PSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNH
Sbjct: 421 PSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNH 480

Query: 481 SVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKS 540
           SVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKS
Sbjct: 481 SVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKS 540

Query: 541 DDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKEL 600
           DDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKEL
Sbjct: 541 DDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKEL 600

Query: 601 GRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAE 660
           GRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAE
Sbjct: 601 GRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAE 660

Query: 661 PPTTLPGTHPGLSETTNPMGHM 682
           PPTTLPGTHPGLSETTNPMGHM
Sbjct: 661 PPTTLPGTHPGLSETTNPMGHM 682


>gi|46370082 transcription factor 12 isoform a [Homo sapiens]
          Length = 706

 Score = 1357 bits (3511), Expect = 0.0
 Identities = 682/706 (96%), Positives = 682/706 (96%), Gaps = 24/706 (3%)

Query: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60
           MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW
Sbjct: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60

Query: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120
           GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY
Sbjct: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120

Query: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180
           SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA
Sbjct: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180

Query: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240
           KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS
Sbjct: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240

Query: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300
           SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG
Sbjct: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300

Query: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360
           STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP
Sbjct: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360

Query: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSL------------------------ 396
           STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSL                        
Sbjct: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCE 420

Query: 397 QSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSL 456
           QSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSL
Sbjct: 421 QSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSL 480

Query: 457 VASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTT 516
           VASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTT
Sbjct: 481 VASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTT 540

Query: 517 EIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREK 576
           EIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREK
Sbjct: 541 EIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREK 600

Query: 577 ERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRE 636
           ERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRE
Sbjct: 601 ERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRE 660

Query: 637 RNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
           RNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM
Sbjct: 661 RNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 706


>gi|46370080 transcription factor 12 isoform a [Homo sapiens]
          Length = 706

 Score = 1357 bits (3511), Expect = 0.0
 Identities = 682/706 (96%), Positives = 682/706 (96%), Gaps = 24/706 (3%)

Query: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60
           MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW
Sbjct: 1   MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSW 60

Query: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120
           GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY
Sbjct: 61  GTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLY 120

Query: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180
           SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA
Sbjct: 121 SRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQA 180

Query: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240
           KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS
Sbjct: 181 KKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS 240

Query: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300
           SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG
Sbjct: 241 SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRG 300

Query: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360
           STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP
Sbjct: 301 STSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360

Query: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSL------------------------ 396
           STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSL                        
Sbjct: 361 STPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLKNRVEQQLHEHLQDAMSFLKDVCE 420

Query: 397 QSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSL 456
           QSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSL
Sbjct: 421 QSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSL 480

Query: 457 VASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTT 516
           VASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTT
Sbjct: 481 VASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTT 540

Query: 517 EIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREK 576
           EIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREK
Sbjct: 541 EIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREK 600

Query: 577 ERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRE 636
           ERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRE
Sbjct: 601 ERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRE 660

Query: 637 RNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
           RNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM
Sbjct: 661 RNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 706


>gi|46370086 transcription factor 12 isoform c [Homo sapiens]
          Length = 512

 Score =  983 bits (2541), Expect = 0.0
 Identities = 489/490 (99%), Positives = 490/490 (100%)

Query: 193 SVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGI 252
           +VYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGI
Sbjct: 23  TVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGI 82

Query: 253 LGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASH 312
           LGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASH
Sbjct: 83  LGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASH 142

Query: 313 TPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTG 372
           TPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTG
Sbjct: 143 TPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTG 202

Query: 373 TSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDI 432
           TSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDI
Sbjct: 203 TSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDI 262

Query: 433 HSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSST 492
           HSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSST
Sbjct: 263 HSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSST 322

Query: 493 DLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVS 552
           DLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVS
Sbjct: 323 DLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVS 382

Query: 553 SRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEK 612
           SRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEK
Sbjct: 383 SRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEK 442

Query: 613 PQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGL 672
           PQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGL
Sbjct: 443 PQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGL 502

Query: 673 SETTNPMGHM 682
           SETTNPMGHM
Sbjct: 503 SETTNPMGHM 512


>gi|145312267 transcription factor 4 isoform a [Homo sapiens]
          Length = 671

 Score =  809 bits (2089), Expect = 0.0
 Identities = 441/692 (63%), Positives = 531/692 (76%), Gaps = 38/692 (5%)

Query: 5   QQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSG 64
           QQRMAA+GTDKELSDLLDFSAMFSPPV+SGK  PT+L S  F+GS +++R  + SWG  G
Sbjct: 4   QQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGG 63

Query: 65  QPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDT 124
            PSPS    R + D   Y DH+    LG+H+ LSP PF+NS +  KT ERGS+S Y R++
Sbjct: 64  HPSPS----RNYGDGTPY-DHMTSRDLGSHDNLSP-PFVNSRIQSKT-ERGSYSSYGRES 116

Query: 125 GLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKV 183
            L GC Q SLL  D+ +G+P  LS + KPG+ YY +S+ + RRRPLH SA    +Q KKV
Sbjct: 117 NLQGCHQQSLLGGDMDMGNPGTLSPT-KPGSQYYQYSSNNPRRRPLHSSAM--EVQTKKV 173

Query: 184 RKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNG 243
           RKVPPGLPSSVYAPS ++ D+NR+SP YPS KP TS F S+FFMQDG H+SSD WSSS+G
Sbjct: 174 RKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG-HHSSDPWSSSSG 232

Query: 244 MSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTS 303
           M+QPG+ G+LG S SH+ QSSSY +LH H+RLSYP HS +  DIN+SLPPMS+FHR  T+
Sbjct: 233 MNQPGYAGMLGNS-SHIPQSSSYCSLHPHERLSYPSHSSA--DINSSLPPMSTFHRSGTN 289

Query: 304 SSPYVAASHTPPINGSDSILGTRGN-AAGSSQTGDALGKALASIYSPDHTSSSFPSNPST 362
              Y  +S TPP NG+DSI+  RG+ AAGSSQTGDALGKALASIYSPDHT++SF SNPST
Sbjct: 290 H--YSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPST 347

Query: 363 PVGSPSPLT-GTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGP 421
           PVGSP  L+ GT+ W R GGQA SSP+YE  LHSLQSR+EDRL+RLDDAIHVLRNHAVGP
Sbjct: 348 PVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGP 407

Query: 422 STSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHS 481
           ST++P GH D+H ++GPSHN  +G L S YG + L++++R + MVGTHRED V+L G+HS
Sbjct: 408 STAMPGGHGDMHGIIGPSHNGAMGGLGSGYG-TGLLSANRHSLMVGTHREDGVALRGSHS 466

Query: 482 VLSSTV--------TTSSTDLNHKTQENYRG---GLQSQSGTVVTTEIKTENKEKDENLH 530
           +L + V        + +S DLN   Q+ YRG   GLQ QS +  ++EIK+++ E DENL 
Sbjct: 467 LLPNQVPVPQLPVQSATSPDLN-PPQDPYRGMPPGLQGQSVSSGSSEIKSDD-EGDENLQ 524

Query: 531 EPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRV 590
           +  SS+D K DD+  +KDIK  +R R SS N+DEDL PEQK EREKERRMANNARERLRV
Sbjct: 525 DTKSSEDKKLDDD--KKDIKSITRSR-SSNNDDEDLTPEQKAEREKERRMANNARERLRV 581

Query: 591 RDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 650
           RDINEAFKELGRM QLHLKS+KPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE
Sbjct: 582 RDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 641

Query: 651 EEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
           EEKVS  S  PP +L G HPG+ + +N MG M
Sbjct: 642 EEKVS--SEPPPLSLAGPHPGMGDASNHMGQM 671


>gi|4507399 transcription factor 4 isoform b [Homo sapiens]
          Length = 667

 Score =  803 bits (2073), Expect = 0.0
 Identities = 438/692 (63%), Positives = 528/692 (76%), Gaps = 42/692 (6%)

Query: 5   QQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSG 64
           QQRMAA+GTDKELSDLLDFSAMFSPPV+SGK  PT+L S  F+GS +++R  + SWG  G
Sbjct: 4   QQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGG 63

Query: 65  QPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDT 124
            PSPS    R + D   Y DH+    LG+H+ LSP PF+NS +  KT ERGS+S Y R++
Sbjct: 64  HPSPS----RNYGDGTPY-DHMTSRDLGSHDNLSP-PFVNSRIQSKT-ERGSYSSYGRES 116

Query: 125 GLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKV 183
            L GC Q SLL  D+ +G+P  LS + KPG+ YY +S+ + RRRPLH SA    +Q KKV
Sbjct: 117 NLQGCHQQSLLGGDMDMGNPGTLSPT-KPGSQYYQYSSNNPRRRPLHSSAM--EVQTKKV 173

Query: 184 RKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNG 243
           RKVPPGLPSSVYAPS ++ D+NR+SP YPS KP TS F S+FFMQDG H+SSD WSSS+G
Sbjct: 174 RKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDG-HHSSDPWSSSSG 232

Query: 244 MSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTS 303
           M+QPG+ G+LG S SH+ QSSSY +LH H+RLSYP HS +  DIN+SLPPMS+FHR  T+
Sbjct: 233 MNQPGYAGMLGNS-SHIPQSSSYCSLHPHERLSYPSHSSA--DINSSLPPMSTFHRSGTN 289

Query: 304 SSPYVAASHTPPINGSDSILGTRGN-AAGSSQTGDALGKALASIYSPDHTSSSFPSNPST 362
              Y  +S TPP NG+DSI+  RG+ AAGSSQTGDALGKALASIYSPDHT++SF SNPST
Sbjct: 290 H--YSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPST 347

Query: 363 PVGSPSPLT-GTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGP 421
           PVGSP  L+ GT+ W R GGQA SSP+YE  LHSLQSR+EDRL+RLDDAIHVLRNHAVGP
Sbjct: 348 PVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGP 407

Query: 422 STSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHS 481
           ST++P GH D+H ++GPSHN  +G L S YG + L++++R + MVGTHRED V+L G+HS
Sbjct: 408 STAMPGGHGDMHGIIGPSHNGAMGGLGSGYG-TGLLSANRHSLMVGTHREDGVALRGSHS 466

Query: 482 VLSSTV--------TTSSTDLNHKTQENYRG---GLQSQSGTVVTTEIKTENKEKDENLH 530
           +L + V        + +S DLN   Q+ YRG   GLQ QS +  ++EIK+++ E DENL 
Sbjct: 467 LLPNQVPVPQLPVQSATSPDLN-PPQDPYRGMPPGLQGQSVSSGSSEIKSDD-EGDENLQ 524

Query: 531 EPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRV 590
           +  SS+D K DD+  +KDIK       +S N+DEDL PEQK EREKERRMANNARERLRV
Sbjct: 525 DTKSSEDKKLDDD--KKDIK-----SITSNNDDEDLTPEQKAEREKERRMANNARERLRV 577

Query: 591 RDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 650
           RDINEAFKELGRM QLHLKS+KPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE
Sbjct: 578 RDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRRE 637

Query: 651 EEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
           EEKVS  S  PP +L G HPG+ + +N MG M
Sbjct: 638 EEKVS--SEPPPLSLAGPHPGMGDASNHMGQM 667


>gi|27777636 transcription factor 3 isoform E12 [Homo sapiens]
          Length = 654

 Score =  597 bits (1539), Expect = e-170
 Identities = 353/699 (50%), Positives = 449/699 (64%), Gaps = 67/699 (9%)

Query: 4   QQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTS 63
           Q QRMA +GTDKELSDLLDFS MF  PV +GK RP +L  +QF GSG+++R  + SWG+ 
Sbjct: 3   QPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSG 62

Query: 64  GQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRD 123
            Q S S+D SR F++  H+++        +H  LS + F+   L GK+ ERG+++ + RD
Sbjct: 63  DQSSSSFDPSRTFSEGTHFTE--------SHSSLSSSTFLGPGLGGKSGERGAYASFGRD 114

Query: 124 TGLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTA-YYSFSATSSRRRPLHDSAALDPLQAK 181
            G+ G  Q+  L  +L L SP  LS SG  GT+ YY   + SSRRR    S    P   K
Sbjct: 115 AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQP---K 171

Query: 182 KVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT-HNSSDLWSS 240
           KVRKVPPGLPSSVY PS + +D+ R++ +YPS K P+S + + F++ DG+ H S++LWS 
Sbjct: 172 KVRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230

Query: 241 SNGMSQPGFGGILGTSTSHM------------SQSSSYGNLHSHDRLSYPPHSVSPTDIN 288
                Q GFG +LG  +S +              SS++G LH H+R+ Y  H     ++N
Sbjct: 231 PG---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGA---EVN 284

Query: 289 TSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYS 348
             LP  SSF     ++   V+ SHTPP++G+DS+LG+RG  AGSS  GDALGKALASIYS
Sbjct: 285 GGLPSASSFSSAPGATYGGVS-SHTPPVSGADSLLGSRGTTAGSS--GDALGKALASIYS 341

Query: 349 PDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLD 408
           PDH+S++F S+PSTPVGSP  L GTSQWPR G     SPSY+  LH LQS++ED LD   
Sbjct: 342 PDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLD--- 398

Query: 409 DAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGT 468
           +AIHVLR+HAVG +        D+H+LL P H    G+L S + G   +    +  + G+
Sbjct: 399 EAIHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGS 446

Query: 469 HRED----SVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKE 524
           H ED    S SL  NH+ L S   T   DL+ +  ++Y  GL     T   +EIK E KE
Sbjct: 447 HPEDGLAGSTSLMHNHAALPSQPGTLP-DLS-RPPDSY-SGLGRAGATAAASEIKREEKE 503

Query: 525 KDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDL-NPEQKIEREKERRMANN 583
            +EN      S++ K       K++K + R RTS   +++DL  PEQK EREKERR+ANN
Sbjct: 504 DEENTSAADHSEEEK-------KELK-APRARTSPDEDEDDLLPPEQKAEREKERRVANN 555

Query: 584 ARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKA 643
           ARERLRVRDINEAFKELGRMCQLHL SEKPQTKLLILHQAV+VIL+LEQQVRERNLNPKA
Sbjct: 556 ARERLRVRDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILNLEQQVRERNLNPKA 615

Query: 644 ACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
           ACLKRREEEKVS V  +P   L   HPGLSE  NP GHM
Sbjct: 616 ACLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 654


>gi|209915594 transcription factor 3 isoform E47 [Homo sapiens]
          Length = 651

 Score =  581 bits (1498), Expect = e-166
 Identities = 347/698 (49%), Positives = 445/698 (63%), Gaps = 68/698 (9%)

Query: 4   QQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTS 63
           Q QRMA +GTDKELSDLLDFS MF  PV +GK RP +L  +QF GSG+++R  + SWG+ 
Sbjct: 3   QPQRMAPVGTDKELSDLLDFSMMFPLPVTNGKGRPASLAGAQFGGSGLEDRPSSGSWGSG 62

Query: 64  GQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRD 123
            Q S S+D SR F++  H+++        +H  LS + F+   L GK+ ERG+++ + RD
Sbjct: 63  DQSSSSFDPSRTFSEGTHFTE--------SHSSLSSSTFLGPGLGGKSGERGAYASFGRD 114

Query: 124 TGLPGC-QSSLLRQDLGLGSPAQLSSSGKPGTA-YYSFSATSSRRRPLHDSAALDPLQAK 181
            G+ G  Q+  L  +L L SP  LS SG  GT+ YY   + SSRRR    S    P   K
Sbjct: 115 AGVGGLTQAGFLSGELALNSPGPLSPSGMKGTSQYYPSYSGSSRRRAADGSLDTQP---K 171

Query: 182 KVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGT-HNSSDLWSS 240
           KVRKVPPGLPSSVY PS + +D+ R++ +YPS K P+S + + F++ DG+ H S++LWS 
Sbjct: 172 KVRKVPPGLPSSVYPPS-SGEDYGRDATAYPSAKTPSSTYPAPFYVADGSLHPSAELWSP 230

Query: 241 SNGMSQPGFGGILGTSTSHM------------SQSSSYGNLHSHDRLSYPPHSVSPTDIN 288
                Q GFG +LG  +S +              SS++G LH H+R+ Y  H     ++N
Sbjct: 231 PG---QAGFGPMLGGGSSPLPLPPGSGPVGSSGSSSTFGGLHQHERMGYQLHGA---EVN 284

Query: 289 TSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYS 348
             LP  SSF     ++   V+ SHTPP++G+DS+LG+RG  AGSS  GDALGKALASIYS
Sbjct: 285 GGLPSASSFSSAPGATYGGVS-SHTPPVSGADSLLGSRGTTAGSS--GDALGKALASIYS 341

Query: 349 PDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLD 408
           PDH+S++F S+PSTPVGSP  L GTSQWPR G     SPSY+  LH LQS++ED LD   
Sbjct: 342 PDHSSNNFSSSPSTPVGSPQGLAGTSQWPRAGAPGALSPSYDGGLHGLQSKIEDHLD--- 398

Query: 409 DAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGT 468
           +AIHVLR+HAVG +        D+H+LL P H    G+L S + G   +    +  + G+
Sbjct: 399 EAIHVLRSHAVGTA-------GDMHTLL-PGH----GALASGFTGPMSLGGRHAGLVGGS 446

Query: 469 HRED----SVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKE 524
           H ED    S SL  NH+ L S   T   DL+ +  ++Y  GL     T   +EIK E KE
Sbjct: 447 HPEDGLAGSTSLMHNHAALPSQPGTLP-DLS-RPPDSY-SGLGRAGATAAASEIKREEKE 503

Query: 525 KDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNA 584
            +EN      S++ K       K++K + R RTSST  DE L+ E+K  R++ERRMANNA
Sbjct: 504 DEENTSAADHSEEEK-------KELK-APRARTSST--DEVLSLEEKDLRDRERRMANNA 553

Query: 585 RERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAA 644
           RER+RVRDINEAF+ELGRMCQ+HLKS+K QTKLLIL QAV VIL LEQQVRERNLNPKAA
Sbjct: 554 RERVRVRDINEAFRELGRMCQMHLKSDKAQTKLLILQQAVQVILGLEQQVRERNLNPKAA 613

Query: 645 CLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM 682
           CLKRREEEKVS V  +P   L   HPGLSE  NP GHM
Sbjct: 614 CLKRREEEKVSGVVGDPQMVLSAPHPGLSEAHNPAGHM 651


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 122/554 (22%), Positives = 205/554 (37%), Gaps = 22/554 (3%)

Query: 13   TDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDS 72
            +D + SD    S   S   +S  +  +    S  S    D    + S  +S       DS
Sbjct: 567  SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626

Query: 73   SRG---FTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGC 129
            S+     +DS   SD  + +   + +    +   NS+    +S+    S  S  +     
Sbjct: 627  SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686

Query: 130  QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPG 189
              S    D    S +  SS      +  S  +++S       S + D   +         
Sbjct: 687  SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746

Query: 190  LPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGF 249
              SS  + S +S D +  S S  S     S  +S     + + NSSD   SSN       
Sbjct: 747  SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN- 805

Query: 250  GGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVA 309
                 + +S  S SS   + +S D  +    S S    ++S    SS    S SS+   +
Sbjct: 806  ----SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861

Query: 310  ASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSP 369
            ++ +   + SDS      N++ SS + D+   + +S  S    SS   S+ S+     S 
Sbjct: 862  SNSSDSSDSSDS-----SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916

Query: 370  LTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGH 429
             + +S        + SS S +NS  S  S   D  D  D +     +++   S S  +  
Sbjct: 917  SSNSSD------SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970

Query: 430  SDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTT 489
            S+  S    S N+   S +S+   SS  + S ++S      + S S N + S  SS  + 
Sbjct: 971  SN-SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029

Query: 490  SSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDI 549
            SS   +  + ++      S S     +   +++ +  ++     SSD   S D S   D 
Sbjct: 1030 SSD--SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087

Query: 550  KVSSRGRTSSTNED 563
              SS    SS + D
Sbjct: 1088 SDSSNSSDSSDSSD 1101



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 123/583 (21%), Positives = 216/583 (37%), Gaps = 18/583 (3%)

Query: 2    NPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWG 61
            N  +   ++  +D + SD  D S   S   +S  +  ++  S+    S   +   ++   
Sbjct: 697  NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756

Query: 62   TSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYS 121
             S   S S DSS   +DS   SD  N S        S +   +++     S   S S  S
Sbjct: 757  DSSDSSNSSDSSDS-SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815

Query: 122  RDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAK 181
             D+       S    D    S +   SS    ++  S S +S+R    + S + D   + 
Sbjct: 816  SDSDSSNSSDSSNSSDSSDSSNSS-DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS 874

Query: 182  KVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTH--------N 233
                      S+  + S +S D +  S S  S    +S  + +    D +         N
Sbjct: 875  NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934

Query: 234  SSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPP 293
            SSD  +SS+            +S S  S +SS  +  +    S   +S   +D + S   
Sbjct: 935  SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994

Query: 294  MSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTS 353
              S    ++S S   + S     +   S      N++ SS + D+   + +S  S    S
Sbjct: 995  SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1054

Query: 354  SSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHV 413
            S+  S+ S+     S  + +S        + SS S ++S  S  S   D  D  D +   
Sbjct: 1055 SN--SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1112

Query: 414  LRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDS 473
              + +   S S  +  S   S    S N+   S +S    SS  + S  +S      + S
Sbjct: 1113 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS 1172

Query: 474  VSLNGNHSVLSSTVTTS-----STDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDEN 528
             S + ++S  SS  + S     S+D +  +  +        S +  +++    +   D N
Sbjct: 1173 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232

Query: 529  LHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQK 571
                 SSD   S D S+  D   SS    S+++ +++ + + K
Sbjct: 1233 -ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 118/523 (22%), Positives = 191/523 (36%), Gaps = 22/523 (4%)

Query: 43   SSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPF 102
            SS  S S        +S  +    S S DSS     +   SD  N S        S +  
Sbjct: 686  SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745

Query: 103  MNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSAT 162
             + +     S   S S  S D+      S          S    +SS    ++  S S+ 
Sbjct: 746  SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805

Query: 163  SSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFA 222
            SS      DS+  D   +           SS  + S +S D +  S S  S +  +S   
Sbjct: 806  SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS--- 862

Query: 223  STFFMQDGTHNSSDLWSSSNGM-SQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHS 281
                    + +SSD   SSN   S         +++S  S SS+  +  S D  +    S
Sbjct: 863  -------NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915

Query: 282  VSPTDINTSLPPMSSFHRGST-SSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALG 340
             S    ++S    SS +  S+ SS+   ++  +   N SDS      N++ SS + D+  
Sbjct: 916  DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS-----SNSSDSSNSSDSSD 970

Query: 341  KALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRM 400
               +      ++S S  S+ S+     S  + +S        + SS S ++S  S  S  
Sbjct: 971  SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030

Query: 401  EDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASS 460
             D  D  D +     + +   S S  + +S   S    S ++   S +S+   SS  + S
Sbjct: 1031 SDSSDSSDSSD---SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087

Query: 461  RSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKT 520
              +S      + S S + + S  SS  + SS   N  + ++      S S     +   +
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSDSSNSSDSS 1145

Query: 521  ENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNED 563
            ++ E  ++     SSD   S D S   D   SS    SS + D
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 121/540 (22%), Positives = 193/540 (35%), Gaps = 31/540 (5%)

Query: 44   SQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFM 103
            S+ +G+G D +G       S   + + DS+ G  ++ +  +  +DS  G  +        
Sbjct: 498  SKDNGNGSDSKGAEDDDSDSTSDTNNSDSN-GNGNNGNDDNDKSDSGKGKSDSSDSDSSD 556

Query: 104  NSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATS 163
            +SN    +    S S  S  +       S         S    +SS    ++  S S+ S
Sbjct: 557  SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS 616

Query: 164  SRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSD--DFNRESPSYPSPKPPTSMF 221
            S        ++     +           S+    S NSD  D +  S S  S     S  
Sbjct: 617  SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD 676

Query: 222  ASTFFMQDGTHNSSDLWSSSNG--------MSQPGFGGILGTSTSHMSQSSSYGNLHSHD 273
            +S+      + +SSD   SSN          S         +S S+ S S S  +  S D
Sbjct: 677  SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD 736

Query: 274  RLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHT----------PPINGSDSIL 323
              +    S S    N+S    SS    S+ SS    +S +             N SDS  
Sbjct: 737  SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS-- 794

Query: 324  GTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQA 383
                N++ SS + D+   + +S     ++S S  S+ S+   + S  + +S     G  +
Sbjct: 795  SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSD-SSDGSDS 853

Query: 384  PSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAP 443
             SS   ++S  S  S   D  +  D +     N +   S S  + +S   S    S N+ 
Sbjct: 854  DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS-DSDSSDSSNSS 912

Query: 444  IGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYR 503
              S +SN   SS  ++S   S        S S N + S  SS  + SS   N     N  
Sbjct: 913  DSSDSSNSSDSSESSNSSDNS------NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966

Query: 504  GGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNED 563
                S S     +   +++ +  ++     SSD   S D S   D   SS    SS + D
Sbjct: 967  DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 112/538 (20%), Positives = 190/538 (35%), Gaps = 20/538 (3%)

Query: 32   NSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL 91
            +S  +  +    S  S +  D    + S  +S     S  S    +DS + SD  N S  
Sbjct: 773  SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832

Query: 92   GAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGK 151
                  S +   + +  G  S+  + S  S  +       S    D    S +  SS+  
Sbjct: 833  SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS- 891

Query: 152  PGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSY 211
                  S S+ SS       S + +   +           SS  + + NS D +  S S 
Sbjct: 892  ------SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945

Query: 212  PSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHS 271
             S     S  +S       + +SSD  SS +  S         + +S  S SS   N   
Sbjct: 946  DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSD 1005

Query: 272  HDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAG 331
                S    S + +D + S    S     S SS    ++  +   + SDS      N++ 
Sbjct: 1006 SSDSSDSSDSSNSSDSSNS----SDSSNSSDSSDSSDSSDSSDSSDSSDS--SDSSNSSD 1059

Query: 332  SSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYEN 391
            SS + D+   + +S  S    SS   S+ S+   + S  + +S        + SS S ++
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSE--SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 392  SLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNY 451
            S  S  S   D  D  D +     + +   S S  +  S   S    S ++   S +S+ 
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 452  GGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSG 511
              SS  + S  +S      + S S + + S  SS  + SS   +     +      S S 
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-----SSDSN 1232

Query: 512  TVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPE 569
                +   +++ +   +     SSD   S  +S+ +    S  G  ++   D D + E
Sbjct: 1233 ESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 109/492 (22%), Positives = 178/492 (36%), Gaps = 11/492 (2%)

Query: 18   SDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFT 77
            SD  D  +  S   ++      +  SS  S S     G  +        S S DSS   +
Sbjct: 813  SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS-S 871

Query: 78   DSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQD 137
            DS + SD  + S        S +   +++    +S+  + S  S  +       S    D
Sbjct: 872  DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 138  LGLGSPAQLSS--SGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVY 195
                S +  SS  S    ++  S S+ SS      DS+  +   +           SS  
Sbjct: 932  NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS 991

Query: 196  APSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGT 255
            + S +S D +  S S  S     S  +S       + NSSD   SS+            +
Sbjct: 992  SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051

Query: 256  STSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPP 315
            S S  S  SS  +  S    S      S +  ++     S+    S SS    ++  +  
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111

Query: 316  INGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSS----SFPSNPSTPVGSPSPLT 371
             + SDS      N++ SS + D+   + +S  S    SS    S  S+ S+     S  +
Sbjct: 1112 SDSSDS--SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169

Query: 372  GTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSD 431
             +S        + SS S ++S  S  S   D  D  D +     + +   S S  +  S 
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229

Query: 432  IHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSL--NGNHSVLSSTVTT 489
              +    S ++   S +SN   SS  + S  ++       DS S   NGN++   S   +
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDS 1289

Query: 490  SSTDLNHKTQEN 501
              +D NH T ++
Sbjct: 1290 EGSDSNHSTSDD 1301



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 112/531 (21%), Positives = 186/531 (35%), Gaps = 23/531 (4%)

Query: 42  GSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTP 101
           G     G+ +      +   + G  S  +D      D P+ SD  N +            
Sbjct: 427 GQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGN-----------D 475

Query: 102 FMNSNLMGKTSERGSFSLYS---RDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYS 158
             NS     +S RG  S  S   +D G           D    S    S S   G     
Sbjct: 476 DANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535

Query: 159 FSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPT 218
            +  S   +   DS+  D   +           S     + +SD  + +S S  S    +
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595

Query: 219 SMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYP 278
           S  +++    D + +SSD   SS+            + +S     S   + +S D     
Sbjct: 596 SDSSNSSDSSDSS-DSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 279 PHSVSPTDINTSLPPMSSFHRGSTSSSPYVAAS----HTPPINGSDSILGTRGNAAGSSQ 334
             S S    N+S    SS    S+SSS    +S     +   N S+S   +  + + SS 
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714

Query: 335 TGDALGKALASIYSPDHTSSSFPSNPSTPVGS--PSPLTGTSQWPRPGGQAPSSPSYENS 392
           + D+     +   S + + SS  SN S    S   S  + +S        + SS S ++S
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774

Query: 393 LHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYG 452
             S  S   D  D  + +     +++   S S  +  S   S    S+++   S NS+  
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS--DSSNSSDS 832

Query: 453 GSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGT 512
             S  +S  S S   +   DS S N + S  SS  + SS   N     +     +S + +
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892

Query: 513 VVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNED 563
             +    + + +  ++ +   SSD   S D S   +   +S    SS + D
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 88/396 (22%), Positives = 150/396 (37%), Gaps = 16/396 (4%)

Query: 198 SPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNS-SDLWSSSNGMSQPGFGGILGTS 256
           S NS D +  S S  S    +S   S+    D + +S SD   SSN            +S
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSD--SDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614

Query: 257 TSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPI 316
            S  S  S   +  S    S        +D N+S    +S    S++SS    +S +   
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674

Query: 317 NGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQW 376
           + S S      N++ SS + D+   + +S  S    S S  S+ S+   S    +  S  
Sbjct: 675 SDSSS-SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS-- 731

Query: 377 PRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLL 436
                 + SS S ++S  S  S   D  D  D +     N +    +S  +  SD  S  
Sbjct: 732 ---SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS-----NSSDSSDSSDSSDSSD--SSN 781

Query: 437 GPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNH 496
               N    S +S+   +S  +S+ S S   +   DS S N + S  SS  + SS   + 
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841

Query: 497 KTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGR 556
               +   G  S S     +   +++ +  ++ +   SSD   S++ S+  D   SS   
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 557 TSSTNEDEDLNPEQKIEREKERRMANNARERLRVRD 592
            S +++  + +         +   ++N+ +     D
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 137/585 (23%), Positives = 220/585 (37%), Gaps = 91/585 (15%)

Query: 23   FSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGT---------TSWGTSGQPSPSYDSS 73
            +S+  SP         T+LG  + S +   + G T         T+ G S + +  Y SS
Sbjct: 2331 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2390

Query: 74   RGFTDSPHYSDHLNDSRLGAHEGLSPTPFMN-------------SNLMGKTSERGSF--S 118
             G T++  +      S  G      PT F +             S   G T E  +F  S
Sbjct: 2391 PGSTETTVFPRTPTTSVRGEE----PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS 2446

Query: 119  LYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPL 178
              S  TGLP   ++L   DLG  S    SSSG  GT      +T+S        + L P 
Sbjct: 2447 PASTQTGLP---ATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS 2503

Query: 179  QAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLW 238
              +        LP S   PS +     + +  Y SP+ P +  +       G        
Sbjct: 2504 STETTT-----LPGSPTTPSLS----EKSTTFYTSPRSPDATLSPATTTSSGVSE----- 2549

Query: 239  SSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFH 298
             SS   SQPG      T T+    S++   L  H   S+     SP   +T+L P S+  
Sbjct: 2550 ESSTSHSQPG-----STHTTAFPDSTTTPGLSRHSTTSHS----SPGSTDTTLLPASTTT 2600

Query: 299  RGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYS---PDHTSSS 355
             G +  S     SH+ P +   ++      A    Q       +  S ++   PD T+SS
Sbjct: 2601 SGPSQES---TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 2657

Query: 356  FPSNPSTPV----GSP----SPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRL 407
                 ST V    GSP    SP + TS  P   G++ +  ++  S H+  S        +
Sbjct: 2658 GIVEASTRVHSSTGSPRTTLSPASSTS--PGLQGESTTFQTHPASTHTTPSPPSTATAPV 2715

Query: 408  DDAIHVLRNHAVGPSTSLPA-----GHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRS 462
            +++    R+    P+T  PA     GHS+  ++   S +A  G+  S+   ++      +
Sbjct: 2716 EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS-GTTPSSAHSTTSGRGEST 2774

Query: 463  ASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTT----EI 518
             S +     +  +L G      ST T   ++ +     + R    + S   +T+    E 
Sbjct: 2775 TSRISPGSTEITTLPG------STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 2828

Query: 519  KTENKEKDENLH---EPPSSDDMKSDDESSQKDIKVSSRGRTSST 560
             T ++ +  + H    P S+      +ES+   +  SS G T +T
Sbjct: 2829 STTSRSQPGSTHSTVSPASTTTPGLSEEST--TVYSSSPGSTETT 2871



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 135/574 (23%), Positives = 205/574 (35%), Gaps = 80/574 (13%)

Query: 23   FSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGT---------TSWGTSGQPSPSYDSS 73
            +S+  SP         T+LG  + S +   + G T         T+ G S + +  Y SS
Sbjct: 2805 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2864

Query: 74   RGFTDSPHYSDHLNDSRLGAHEGLSPTPFMN-------------SNLMGKTSERGSF--S 118
             G T++  +      S  G      PT F +             S   G T E  +F  S
Sbjct: 2865 PGSTETTVFPRSTTTSVRGEE----PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGS 2920

Query: 119  LYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPL 178
              S  TGLP   ++L   DLG  S    SSSG  GT      +T+S        + L P 
Sbjct: 2921 PASTQTGLP---ATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS 2977

Query: 179  QAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLW 238
              +        LP S   PS +     + +  Y SP+ P +  +       G        
Sbjct: 2978 STETTT-----LPGSPTTPSLS----EKSTTFYTSPRSPDATLSPATTTSSGVSE----- 3023

Query: 239  SSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFH 298
             SS   SQPG      T T+    S++   L      S+     +   ++      SS  
Sbjct: 3024 ESSTSHSQPG-----STHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLG 3078

Query: 299  RGSTS--SSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHT---- 352
            + ST+  SSP    +   P    D+I  T G    S+ T  + G    ++     T    
Sbjct: 3079 QQSTTFHSSPGDTETTLLP---DDTI--TSGLVEASTPTHSSTGSLHTTLTPASSTSAGL 3133

Query: 353  ---SSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDD 409
               S++F S PS+   +PSP   T+          S PS   + H   S     L R ++
Sbjct: 3134 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF--SASSTTLGRSEE 3191

Query: 410  AIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTH 469
            +  V  +      T+L    S    L+G    +PI S     G +   A   S +  G  
Sbjct: 3192 STTV-HSSPGATGTALFPTRSATSVLVGEPTTSPISS-----GSTETTALPGSTTTAGLS 3245

Query: 470  REDSVSLNGNHS---VLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKD 526
             + +   +   S    LS   TTSS      T  + R G    +    +T +   ++E  
Sbjct: 3246 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 3305

Query: 527  ENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSST 560
             +   P S+D   S   ++      SS G  S+T
Sbjct: 3306 ASHSSPGSTDTTLSPGSTT-----ASSLGPESTT 3334



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 124/552 (22%), Positives = 207/552 (37%), Gaps = 63/552 (11%)

Query: 38   PTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGL 97
            PTT  SSQ S       G TT+  + GQ S ++ SS G T++    D    S  G  E  
Sbjct: 1496 PTTSHSSQGSTEATLSPGSTTA-SSLGQQSTTFHSSPGDTETTLLPDDTITS--GLVEAS 1552

Query: 98   SPTPFMNSNLMGKTSERGSFS--LYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTA 155
            +PT     +L    +   S S  L    T      SS    D     P   ++  +  T 
Sbjct: 1553 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS---SDTTPSPPGTTAAPVEVSTT 1609

Query: 156  YYS---------FSATSSRRRPLHDSAALDPLQ-AKKVRKVPPGLPSSVYAPSPNSDDFN 205
            Y+S         FSA+S+      +S  +     A      P    +SV    P +   +
Sbjct: 1610 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 1669

Query: 206  R---ESPSYPSPKPPTSMF--ASTFFMQDGTHNS--SDLWSSSNGMSQPGFGGILGTSTS 258
                E+ + P       +   ++TF+    + ++  S   ++S+G+S+          ++
Sbjct: 1670 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1729

Query: 259  HMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPING 318
            H +       +    + S   HS SP   +T+L P S+    ++S  P     H+ P + 
Sbjct: 1730 HTTAFPGSTTMPGVSQESTASHS-SPGSTDTTLSPGSTT---ASSLGPESTTFHSSPGST 1785

Query: 319  SDSILGTRGNAAGSSQTGDALGKALASIYSP---------DHTSSSFPSNPSTPVGSPSP 369
              ++L     A+G  +    +  +  S ++             S++F S PS+    P+P
Sbjct: 1786 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1845

Query: 370  LTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGH 429
             T TS +      +  SPS   + H   S     L R +++  V  +     +T  PA  
Sbjct: 1846 PTTTSAFVELSTTSHGSPSSTPTTHF--SASSTTLGRSEESTTVHSSPVATATTPSPA-R 1902

Query: 430  SDIHSLLGPS---HNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLN--------- 477
            S    L+  S   H++P GS  + +   S  AS RS     +H   + +++         
Sbjct: 1903 STTSGLVEESTAYHSSP-GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL 1961

Query: 478  -----GNHSVLSSTVTT----SSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDEN 528
                   HS   ST TT    SST      +       Q  +GT+V     T +    E+
Sbjct: 1962 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 2021

Query: 529  LHEPPSSDDMKS 540
               P SS  M++
Sbjct: 2022 TTSPISSGSMET 2033



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 127/556 (22%), Positives = 212/556 (38%), Gaps = 70/556 (12%)

Query: 24  SAMFSPPVNSGKTRP-----TTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTD 78
           S+  + P  SG T       TT  SS  S         +T+ G S + +P + S      
Sbjct: 426 SSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATAT 485

Query: 79  SPH-----YSDHLNDSRLGAHEGLSPTPFMN----SNLMGKTSERGSFSLYSRDTGLPGC 129
           +P       S H+ +S    H     T  M+    S   G + E  +F   +  T     
Sbjct: 486 TPPPARSATSGHVEEST-AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT----- 539

Query: 130 QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPG 189
           +SS       L   +  SS G   T ++  S+T S R     ++   P  A     +P G
Sbjct: 540 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP-DAMATTVLPAG 598

Query: 190 LPSSVYA----PSPNSDDFNRESPSYP--SPKPPTSMFASTFFMQDGTHNSSDLWSS--S 241
              SV      PSP S   + E+ + P  + KP  S  ++TF+    + +++ L +S  S
Sbjct: 599 STPSVLVGDSTPSPISSG-SMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTS 657

Query: 242 NGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGS 301
           +G+S+          ++H +       +    + S   HS SP   +T+L P S+    +
Sbjct: 658 SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS-SPGPTDTTLSPGSTT---A 713

Query: 302 TSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSP---------DHT 352
           +S  P     H+ P +   ++L     A+G  +    +  +  S ++             
Sbjct: 714 SSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGE 773

Query: 353 SSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIH 412
           S++F S PS+    P+P T TS +  P   +  SPS   + H         L       H
Sbjct: 774 STTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYH 833

Query: 413 VLRNHAVGPSTSLPAGHSDIHSLLG----PSHNAPIGSLNSNYGGSSLVASSRSASMVGT 468
                + G + ++    SD  S  G     SH++   +++S        A S ++++V  
Sbjct: 834 ----SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS--------APSTTSALV-- 879

Query: 469 HREDSVSLNGNHSVLSSTVTT----SSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKE 524
             E+  S    HS   ST TT    SST      +       Q  +GT+V     T +  
Sbjct: 880 --EEPTSY---HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVL 934

Query: 525 KDENLHEPPSSDDMKS 540
             E+   P SS  M++
Sbjct: 935 LGESTTSPISSGSMET 950



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 119/557 (21%), Positives = 212/557 (38%), Gaps = 73/557 (13%)

Query: 38   PTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL------ 91
            PTT  SSQ S       G TT+  + GQ S ++ SS G T++    D    S L      
Sbjct: 4136 PTTSHSSQGSTEATLSPGSTTA-SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTP 4194

Query: 92   ------GAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQ 145
                    H  L+P    ++ L  +++   S+   S  T  P   +++         P +
Sbjct: 4195 THSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAV---------PVE 4245

Query: 146  LSSS--GKPG---TAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPN 200
            +S++   +P    T ++S S+T+  R     +    P  A      P    +SV    P 
Sbjct: 4246 VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSP-GATGTALFPTRSATSVLVGEPT 4304

Query: 201  SDDFNR---ESPSYPSPKPPTSMF--ASTFFMQDGTHNS--SDLWSSSNGMSQPGFGGIL 253
            +   +    E+ + P       +   ++TF+    + ++  S   ++S+G+S+       
Sbjct: 4305 TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 4364

Query: 254  GTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHT 313
               + H +   S   +    + S   HS SP   +T+L P S+    ++S  P     H+
Sbjct: 4365 RPGSMHTTAFPSSTTMPGVSQESTASHS-SPGSTDTTLSPGSTT---ASSLGPESTTFHS 4420

Query: 314  PPINGSDSILGTRGNAAGSSQTGDALGKALASIYSP---------DHTSSSFPSNPSTPV 364
             P +   ++L     A+G  +    +  +  S ++             S++F S P++  
Sbjct: 4421 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 4480

Query: 365  GSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTS 424
             +P+P T TS +      +  SPS   + H   S     L R +++  V  +     +T 
Sbjct: 4481 TTPAPPTTTSAFVELSTTSHGSPSSTPTTHF--SASSTTLGRSEESTTVHSSPVATATTP 4538

Query: 425  LPAGHSDIHSLLGPS---HNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLN---- 477
             PA  S    L+  S   H++P GS  + +   S   S R      +H   + +++    
Sbjct: 4539 SPA-RSTTSGLVEESTTYHSSP-GSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPS 4596

Query: 478  ----------GNHSVLSSTVTT----SSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENK 523
                        HS   ST TT    SST      +       Q  +GT+V     T + 
Sbjct: 4597 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 4656

Query: 524  EKDENLHEPPSSDDMKS 540
               E+   P SS  M++
Sbjct: 4657 LLGESTTSPISSGSMET 4673



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 120/552 (21%), Positives = 205/552 (37%), Gaps = 63/552 (11%)

Query: 38   PTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGL 97
            PT   SSQ S       G TT+  + GQ S ++ SS G T++    D    S  G  E  
Sbjct: 3053 PTASHSSQGSTEATLSPGSTTA-SSLGQQSTTFHSSPGDTETTLLPDDTITS--GLVEAS 3109

Query: 98   SPTPFMNSNLMGKTSERGSFS--LYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTA 155
            +PT     +L    +   S S  L    T      SS    D     P   ++  +  T 
Sbjct: 3110 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS---SDTTPSPPGTTAAPVEVSTT 3166

Query: 156  YYS---------FSATSSRRRPLHDSAALDPLQ-AKKVRKVPPGLPSSVYAPSPNSDDFN 205
            Y+S         FSA+S+      +S  +     A      P    +SV    P +   +
Sbjct: 3167 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 3226

Query: 206  R---ESPSYPSPKPPTSMF--ASTFFMQDGTHNS--SDLWSSSNGMSQPGFGGILGTSTS 258
                E+ + P       +   ++TF+    + ++  S   ++S+G+S+          ++
Sbjct: 3227 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 3286

Query: 259  HMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPING 318
            H +       +    + S   HS SP   +T+L P S+    ++S  P     H+ P + 
Sbjct: 3287 HTTAFPGSTTMPGVSQESTASHS-SPGSTDTTLSPGSTT---ASSLGPESTTFHSGPGST 3342

Query: 319  SDSILGTRGNAAGSSQTGDALGKALASIYSP---------DHTSSSFPSNPSTPVGSPSP 369
              ++L     A+G  +    +  +  S ++             S++F S P++   +P+P
Sbjct: 3343 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 3402

Query: 370  LTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGH 429
             T TS +      +  SPS   + H   S     L R +++  V  +     +T  PA  
Sbjct: 3403 PTTTSAFVELSTTSHGSPSSTPTTHF--SASSTTLGRSEESTTVHSSPVATATTPSPA-R 3459

Query: 430  SDIHSLLGPS---HNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLN--------- 477
            S    L+  S   H++P GS  + +   S   S R      +H   + +++         
Sbjct: 3460 STTSGLVEESTTYHSSP-GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSAL 3518

Query: 478  -----GNHSVLSSTVTT----SSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDEN 528
                   HS   ST TT    SST      +       Q  +GT+V     T +    E+
Sbjct: 3519 VEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGES 3578

Query: 529  LHEPPSSDDMKS 540
               P SS  M++
Sbjct: 3579 TTSPISSGSMET 3590



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 123/588 (20%), Positives = 205/588 (34%), Gaps = 91/588 (15%)

Query: 32   NSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL 91
            +S ++  TTL  +  + SG+ E   T+        + ++  S   T +P  S H   S  
Sbjct: 971  SSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDS---TTTPGLSRHSTTSH- 1026

Query: 92   GAHEGLSPTPFMNSNLM----GKTSERGSFSLYSRDTGL-PGCQSSLLRQDLGLGSPAQL 146
             +  G + T  + ++       + S     S  S DT L PG  ++L     G  S    
Sbjct: 1027 -SSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTAL---SFGQESTTFH 1082

Query: 147  SSSGKPGTAYYSFSATSS----RRRPLHDSAALDPLQAKKVRKVPPGL------------ 190
            S+ G   T  +  S TSS        +H S               PGL            
Sbjct: 1083 SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 1142

Query: 191  --------PSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSN 242
                    PS+  AP   S  ++R   S P+   P S   S      G    S ++ SS 
Sbjct: 1143 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS------GHSEKSTIFHSSP 1196

Query: 243  GMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGST 302
              S         T++     ++S  +  S +  + P  + +P     S    SS    +T
Sbjct: 1197 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256

Query: 303  SSSPYVAASHTPPINGSDSIL------GTRGNAAGSSQTGDALGKALASIYSPDHTSSS- 355
            + SP   AS T    G +S         T    + +S T   L +   ++YS    S+  
Sbjct: 1257 TLSP---ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTET 1313

Query: 356  --FPSNPSTPVGSPSPLTGTS-----------QWPRPGGQAPSSPSYENSLHSLQSRMED 402
              FP + +T V    P T  S           +     G    S ++  S  S Q+ +  
Sbjct: 1314 TVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 1373

Query: 403  RLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRS 462
             L   D             ST+ P+      + L P+ +   G +  +       +S+ +
Sbjct: 1374 TLTTAD---------LGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 1424

Query: 463  ASMVGTHREDSVSLNGNHSVLS--------STVTTSSTDLNHKTQENYRGGLQSQSGTVV 514
             ++ G+    S+S        S        S  TT+S+ ++ ++  ++     SQ G+  
Sbjct: 1425 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH-----SQPGSTH 1479

Query: 515  TTEIKTENKEKDENLHEPPSSDDMKSDDES--SQKDIKVSSRGRTSST 560
            TT         D +  EP +S   +   E+  S      SS G+ S+T
Sbjct: 1480 TTAFPDSTTTSDLS-QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 1526



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 124/588 (21%), Positives = 208/588 (35%), Gaps = 91/588 (15%)

Query: 32   NSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL 91
            +S ++  TTL  +  + SG+ E   T+        + ++  S   T +P  S H   S  
Sbjct: 3611 SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS---TTTPGLSRHSTTSH- 3666

Query: 92   GAHEGLSPTPFMNSNLMGKTSERGSFSLYSR----DTGL-PGCQSSLLRQDLGLGSPAQL 146
             +  G + T  + ++     S + S + +S     DT L PG  ++L     G  S    
Sbjct: 3667 -SSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTAL---SFGQESTTFH 3722

Query: 147  SSSGKPGTAYYSFSATSS----RRRPLHDSAALDPLQAKKVRKVPPGL------------ 190
            SS G   T  +  S TSS        +H S               PGL            
Sbjct: 3723 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 3782

Query: 191  --------PSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSN 242
                    PS+  AP   S  ++R   S P+   P S   S      G    S ++ SS 
Sbjct: 3783 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS------GHSEKSTIFHSSP 3836

Query: 243  GMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGST 302
              S         T++     ++S  +  S +  + P  + +P     S    SS    +T
Sbjct: 3837 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 3896

Query: 303  SSSPYVAASHTPPINGSDSIL------GTRGNAAGSSQTGDALGKALASIY--SPDHTSS 354
            + SP   AS T    G +S         T    + +S T   L +   ++Y  SP  T +
Sbjct: 3897 TLSP---ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 3953

Query: 355  S-FPSNPSTPVGSPSPLTGTS-----------QWPRPGGQAPSSPSYENSLHSLQSRMED 402
            + FP + +T V    P T  S           +     G    S ++  S  S Q+ +  
Sbjct: 3954 TVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 4013

Query: 403  RLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRS 462
             L   D             ST+ P+      + L P+ +   G +  +       +S+ +
Sbjct: 4014 TLTTAD---------LGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 4064

Query: 463  ASMVGTHREDSVSLNGNHSVLS--------STVTTSSTDLNHKTQENYRGGLQSQSGTVV 514
             ++ G+    S+S        S        S  TT+S+ ++ ++  ++     SQ G+  
Sbjct: 4065 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH-----SQPGSTH 4119

Query: 515  TTEIKTENKEKDENLHEPPSSDDMKSDDES--SQKDIKVSSRGRTSST 560
            TT           +  EP +S   +   E+  S      SS G+ S+T
Sbjct: 4120 TTAFPDSTTTSGLS-QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 118/568 (20%), Positives = 196/568 (34%), Gaps = 88/568 (15%)

Query: 32   NSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL 91
            +S ++  TTL  +  + SG+ E   T+        + ++  S   T +P  S H   S  
Sbjct: 2054 SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS---TTTPGLSRHSTTSH- 2109

Query: 92   GAHEGLSPTPFMNSNLMGKTSERGSFSLYSR----DTGL-PGCQSSLLRQDLGLGSPAQL 146
             +  G + T  + ++       + S + +S     DT L PG  ++L     G  S    
Sbjct: 2110 -SSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTAL---SFGQESTTFH 2165

Query: 147  SSSGKPGTAYYSFSATSS----RRRPLHDSAALDPLQAKKVRKVPPGL------------ 190
            SS G   T  +  S TSS        +H S               PGL            
Sbjct: 2166 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 2225

Query: 191  --------PSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSN 242
                    PS+  AP   S  ++R   S P+   P S   S      G    S ++ SS 
Sbjct: 2226 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS------GHSEKSTIFHSSP 2279

Query: 243  GMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGST 302
              S         T++     ++S  +  S +  + P  + +P     S    SS    +T
Sbjct: 2280 DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 2339

Query: 303  SSSPYVAASHTPPINGSDSIL------GTRGNAAGSSQTGDALGKALASIY--SPDHTSS 354
            + SP   AS T    G +S         T    + +S T   L +   ++Y  SP  T +
Sbjct: 2340 TLSP---ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 2396

Query: 355  S-FPSNPSTPVGSPSPLTGTS-----------QWPRPGGQAPSSPSYENSLHSLQSRMED 402
            + FP  P+T V    P T  S           +     G    S ++  S  S Q+ +  
Sbjct: 2397 TVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 2456

Query: 403  RLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRS 462
             L   D             ST+ P+      + L P+ +   G +  +       +S+ +
Sbjct: 2457 TLTTAD---------LGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTET 2507

Query: 463  ASMVGTHREDSVSLNGNHSVLS--------STVTTSSTDLNHKTQENYRGGLQSQSGTVV 514
             ++ G+    S+S        S        S  TT+S+ ++ ++  ++     SQ G+  
Sbjct: 2508 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH-----SQPGSTH 2562

Query: 515  TTEIKTENKEKDENLHEPPSSDDMKSDD 542
            TT           + H   S     S D
Sbjct: 2563 TTAFPDSTTTPGLSRHSTTSHSSPGSTD 2590



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 83/359 (23%), Positives = 128/359 (35%), Gaps = 36/359 (10%)

Query: 56  GTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL-------GAHEGLSPTPFMNSNLM 108
           GTT+  + G  S ++ SS G+T +    D+   S L        +  G   T    S+  
Sbjct: 353 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSST 412

Query: 109 GKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSAT---SSR 165
               E  +F  +          S      + L +    S S  P T + + S T   S  
Sbjct: 413 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 472

Query: 166 RRPLHDSAALDPLQAKKVRKVPPG--LPSSVYAPSPNSDD---FNRESPSYPSPKPPTSM 220
             P+H S           R    G    S+ Y  SP S     F   S +    +   + 
Sbjct: 473 STPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATF 532

Query: 221 FASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILG-TSTSHMSQSSSYGNLHSHDRLSYPP 279
             ST      TH  S   S++  ++   +   LG T T+H   SS+        + S   
Sbjct: 533 HGST------THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKAS--- 583

Query: 280 HSVSPTDINTSLPPMS--SFHRGSTSSSPYVAAS-HTPPINGSDSILGTRGNAAGSSQTG 336
           HS       T LP  S  S   G ++ SP  + S  T  + GS     T+   +  S T 
Sbjct: 584 HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST----TKPGLSEKSTTF 639

Query: 337 DALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWP----RPGGQAPSSPSYEN 391
            +  ++  + + P   +SS  S  ST   S    T T+ +P     PG    S+ S+ +
Sbjct: 640 YSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 698



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 96/484 (19%), Positives = 171/484 (35%), Gaps = 36/484 (7%)

Query: 37  RPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEG 96
           R   LG  +F+  G D+  G     + G P      + G  +       +N S       
Sbjct: 105 RVKNLGLVEFASPG-DDGDGRAEGFSLGLPLSEQARAAGAREKERQETVINHSTFSGFSQ 163

Query: 97  LSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAY 156
           ++ +  +N+++ G T+   + S     T       S+        +   L SS   G + 
Sbjct: 164 ITGST-VNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSE 222

Query: 157 YSF------SATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPS 210
            S        AT +   P H + ++   + K        + ++    S  +   + +S +
Sbjct: 223 ESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTT 282

Query: 211 -YPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNL 269
            Y SP+ P    +       G    S     +   S+PG    +    S      S  + 
Sbjct: 283 FYSSPRSPDRTLSPARTTSSGVSEKS-----TTSHSRPGPTHTIAFPDSTTMPGVSQEST 337

Query: 270 HSHDRLSYPPHSVSP-TDINTSLPPMSS-FHRGSTSSSPYVAASHTPPINGSDSILGTRG 327
            SH        ++SP T   +SL P S+ FH     SSP    +   P N + S L    
Sbjct: 338 ASHSIPGSTDTTLSPGTTTPSSLGPESTTFH-----SSPGYTKTTRLPDNTTTSGLLEAS 392

Query: 328 NAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSP 387
               SS        + +S  + +   ++F S PS+   SP+P   TS + +      SSP
Sbjct: 393 TPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP 452

Query: 388 SYENSLHSLQSRMEDRLDRLDDAIH---VLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPI 444
           S   + H   S            +H   V       P+ S  +GH +  +     H +P 
Sbjct: 453 SSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAY---HRSP- 508

Query: 445 GSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRG 504
                   GS+       +S    H E+S + +G+ +   S+  +++  L H +  +  G
Sbjct: 509 --------GSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLG 560

Query: 505 GLQS 508
             ++
Sbjct: 561 STET 564


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 110/502 (21%), Positives = 195/502 (38%), Gaps = 80/502 (15%)

Query: 38   PTTL---GSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDS--RLG 92
            PTTL   GS+  + +      GT+   +S   + +  S    T S H+++  + S   + 
Sbjct: 1656 PTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNIT 1715

Query: 93   AHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLS----S 148
             +   + TP M     G +  R SFS     T L    SS    ++   S   ++    S
Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775

Query: 149  SGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRES 208
            +G      ++ SATSSR            L        PP   + + +  P +    + +
Sbjct: 1776 TGTRTPVAHTTSATSSR------------LPTPFTTHSPPTGTTPISSTGPVTATSFQTT 1823

Query: 209  PSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGN 268
             +YP+P  P +           TH    + S S  +  P    ++  + + M+ S+S   
Sbjct: 1824 TTYPTPSHPHTTLP--------TH----VPSFSTSLVTPSTHTVIIPTHTQMATSAS--- 1868

Query: 269  LHSHDRLSYPPHS-------------VSPTDINTSLPPMSSFHRGSTSSS-PY-VAASHT 313
            +HS    + PP +             ++PT   TS  P SSF    TS+S PY  +++H 
Sbjct: 1869 IHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSP-SSFSTAKTSTSLPYHTSSTHH 1927

Query: 314  PPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGT 373
            P +  + +   T  + +  ++T  A   + +S   P   ++  P   S+P  S  P+T T
Sbjct: 1928 PEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTAT 1987

Query: 374  S-----QWPRPGGQAPSSPSY---------ENSLHSLQSRMEDRLDRLDDAIHVLRNHAV 419
            S      +P P     + P++           S H++      ++     +IH      V
Sbjct: 1988 SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQM-ATSASIHSTPTGTV 2046

Query: 420  GPSTSLPAGHSDIHSLLGPSHNAP---IGSLNSNYGGSSLVASSRSASMVGTHREDSVSL 476
             P T+L A         G +H AP   + +  ++   SS   ++ S+S + +     +  
Sbjct: 2047 PPPTTLKA--------TGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISS--SSWLPQ 2096

Query: 477  NGNHSVLSSTVTTSSTDLNHKT 498
            N +    SS +TT    L+  T
Sbjct: 2097 NSSSRPPSSPITTQLPHLSSAT 2118



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 120/548 (21%), Positives = 203/548 (37%), Gaps = 114/548 (20%)

Query: 28   SPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLN 87
            +PP+      PTT G+SQ            +S+ T+  P+    S    T S H+ +   
Sbjct: 1499 APPIT-----PTTSGTSQ----------AHSSFSTNKTPT----SLHSHTSSTHHPEVTP 1539

Query: 88   DSRL----GAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSP 143
             S            + TP  ++N    +     F+ +S  TG                SP
Sbjct: 1540 TSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTG---------------SSP 1584

Query: 144  AQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPS----- 198
               SS+G P TA  SF  T++   P H    L          VPP   +S+  PS     
Sbjct: 1585 --FSSTG-PMTAT-SFKTTTTYPTPSHPQTTLPT-------HVPP-FSTSLVTPSTHTVI 1632

Query: 199  -PNSDDFNRESPSYPSPK----PPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGIL 253
             P        +  +  P     PPT++ A+       TH +  +  +++G SQ      L
Sbjct: 1633 TPTHAQMATSASIHSMPTGTIPPPTTLKAT-----GSTHTAPTMTLTTSGTSQALSS--L 1685

Query: 254  GTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPM-----------SSFHRGST 302
             T+ +  S  S   + H  +  S    +++P   +T  PPM           SSF    T
Sbjct: 1686 NTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKT 1745

Query: 303  SSS--PYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNP 360
            S+S   + +++H P +  + +   T  + +  ++T  A   +  S   P   ++  P   
Sbjct: 1746 STSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTG 1805

Query: 361  STPVGSPSPLTGTS-----QWPRPGGQAPS----SPSYENSL-----HSLQSRMEDRLDR 406
            +TP+ S  P+T TS      +P P     +     PS+  SL     H++      ++  
Sbjct: 1806 TTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQM-A 1864

Query: 407  LDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMV 466
               +IH +    + P T++ A         G +H AP   +     G+S   SS S +  
Sbjct: 1865 TSASIHSMPTGTIPPPTTIKA--------TGSTHTAP--PMTPTTSGTSQSPSSFSTAKT 1914

Query: 467  GTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKD 526
             T      S + +H  ++ T TT+ T  +  T         +++    TT   +      
Sbjct: 1915 STSLPYHTS-STHHPEVTPTSTTNITPKHTST--------GTRTPVAHTTSASSSRLPTP 1965

Query: 527  ENLHEPPS 534
               H PP+
Sbjct: 1966 FTTHSPPT 1973



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 100/431 (23%), Positives = 170/431 (39%), Gaps = 75/431 (17%)

Query: 58   TSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSF 117
            T+ GTS  PS S+ +++  T  P+++   +   +        TP   +N+  K +  G+ 
Sbjct: 1898 TTSGTSQSPS-SFSTAKTSTSLPYHTSSTHHPEV--------TPTSTTNITPKHTSTGTR 1948

Query: 118  SLYSRDTGLPGCQSSLLRQDLGLGSPAQLSS---SGKPGTAYYSFSATSSRRRPLHDSAA 174
            +  +  T      SS L       SP   SS   S  P TA  SF  T++   P H    
Sbjct: 1949 TPVAHTTS---ASSSRLPTPFTTHSPPTGSSPFSSTGPMTAT-SFQTTTTYPTPSHPQTT 2004

Query: 175  LDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPK----------PPTSMFAST 224
            L          VPP   +S+  PS ++      +    S            PPT++ A+ 
Sbjct: 2005 LPT-------HVPP-FSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKAT- 2055

Query: 225  FFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSP 284
                  TH +  +  +++G SQ        T++S    SSS+   +S  R    P +   
Sbjct: 2056 ----GSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQL 2111

Query: 285  TDINTSLPPMSSFHRGSTSSSP----------YVAASHTPPINGSDSILGTRGNAAGSSQ 334
              ++++  P+S+ ++ S+S SP          YV +SH+ P   S S+        G+S 
Sbjct: 2112 PHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSV--------GTSS 2163

Query: 335  TGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLH 394
            +  +      ++ S  H  SS  ++P+T   S SPL             PSSP+   ++ 
Sbjct: 2164 SFVSAPVHSTTLSSGSH--SSLSTHPTTASVSASPL------------FPSSPAASTTIR 2209

Query: 395  SLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGS 454
            +           L  A+  +    V P+   P+ H    ++  PS      S ++    S
Sbjct: 2210 ATLPHTISSPFTL-SALLPISTVTVSPT---PSSHLASSTIAFPSTPRTTASTHTAPAFS 2265

Query: 455  SLVASSRSASM 465
            S   +SRS S+
Sbjct: 2266 SQSTTSRSTSL 2276



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 93/449 (20%), Positives = 164/449 (36%), Gaps = 64/449 (14%)

Query: 93   AHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQS---SLLRQDLGLGSPAQLSSS 149
            A  GL PT  + S     T  + + +  +  T  P   S   S  R  + L +PA   +S
Sbjct: 1282 ATSGLPPTATLRSTATKPTVTQAT-TRATASTASPATTSTAQSTTRTTMTLPTPATSGTS 1340

Query: 150  GK---------PGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLP---SSVYAP 197
                       PGT   +   T  R  P   +    P   +  R          ++    
Sbjct: 1341 PTLPKSTNQELPGTT--ATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYT 1398

Query: 198  SPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTST 257
            +P +       P+  SP P T    +T F    T+ +     ++     P F   L T +
Sbjct: 1399 TPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPS 1458

Query: 258  SHM-------SQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPM-----------SSFHR 299
            +H          ++S  N  +      PP ++  T    + PP+           SSF  
Sbjct: 1459 THTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFST 1518

Query: 300  GSTSSS--PYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFP 357
              T +S   + +++H P +  + +   T    +  ++T  A   +  S   P   ++  P
Sbjct: 1519 NKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSP 1578

Query: 358  SNPSTPVGSPSPLTGTS-----QWPRPGGQAPSSPSY---------ENSLHSLQSRMEDR 403
               S+P  S  P+T TS      +P P     + P++           S H++ +    +
Sbjct: 1579 PTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQ 1638

Query: 404  LDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSA 463
            +     +IH +    + P T+L A         G +H AP  +L ++  G+S   SS + 
Sbjct: 1639 M-ATSASIHSMPTGTIPPPTTLKA--------TGSTHTAPTMTLTTS--GTSQALSSLNT 1687

Query: 464  SMVGTHREDSVSLNGNHSVLSSTVTTSST 492
            +   T      S + +H+  +ST TT+ T
Sbjct: 1688 AKTSTSLHSHTS-STHHAEATSTSTTNIT 1715



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 90/395 (22%), Positives = 142/395 (35%), Gaps = 65/395 (16%)

Query: 36   TRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHE 95
            T     GSS FS +G      T+   T+  P+PS+  +   T  P +S  L         
Sbjct: 1968 THSPPTGSSPFSSTG--PMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSL--------- 2016

Query: 96   GLSPTPFMNSNLMGKTSERG-SFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGT 154
                TP  ++ ++   ++   S S++S  TG     ++L        +P    ++     
Sbjct: 2017 ---VTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQ 2073

Query: 155  AYYSFSATSSRRRPLHDSAALDPLQAKKVRKVP--PGLPSSVYAPSPNSDDFNRESPSYP 212
             + SFS  ++    +  S+ L    + +    P    LP    A +P S      S   P
Sbjct: 2074 THSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSP 2133

Query: 213  SPKPPTSMFASTFFMQDGTHNSS-DLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHS 271
            SP  P+++ +           SS  + +SS+ +S P     L +S SH S S+       
Sbjct: 2134 SPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTL-SSGSHSSLSTHPTTASV 2192

Query: 272  HDRLSYPPHSVSPTDINTSLP---------------------PMSSFHRGSTS----SSP 306
                 +P    + T I  +LP                     P  S H  S++    S+P
Sbjct: 2193 SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTP 2252

Query: 307  YVAAS-HTPPINGSDSI------LGTRGNAAGS-SQTGDALGKALASIYS-----PDHT- 352
               AS HT P   S S       L TR   +G  S T    G   + + +     P  T 
Sbjct: 2253 RTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTL 2312

Query: 353  -------SSSFPSNPSTPVGSPSPLTGTSQWPRPG 380
                   +SS  ++ STP  +P    GT     PG
Sbjct: 2313 SPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPG 2347


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 126/556 (22%), Positives = 212/556 (38%), Gaps = 70/556 (12%)

Query: 24  SAMFSPPVNSGKTRP-----TTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTD 78
           S+  + P  SG T       TT  SS  S         +T+ G S + +P + S      
Sbjct: 282 SSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATAT 341

Query: 79  SPH-----YSDHLNDSRLGAHEGLSPTPFMN----SNLMGKTSERGSFSLYSRDTGLPGC 129
           +P       S H+ +S    H     T  M+    S   G + E  +F   +  T     
Sbjct: 342 TPPPARSATSGHVEEST-AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT----- 395

Query: 130 QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPG 189
           +SS       L   +  SS G   T ++  S+T S R     ++   P  A     +P G
Sbjct: 396 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP-DAMATTVLPAG 454

Query: 190 LPSSVYA----PSPNSDDFNRESPSYP--SPKPPTSMFASTFFMQDGTHNSSDLWS--SS 241
              SV      PSP S   + E+ + P  + KP  S  ++TF+    + +++ L +  +S
Sbjct: 455 STPSVLVGDSTPSPISSG-SMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPARMTS 513

Query: 242 NGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGS 301
           +G+S+          ++H +       +    + S   HS SP   +T+L P S+    +
Sbjct: 514 SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS-SPGPTDTTLSPGSTT---A 569

Query: 302 TSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSP---------DHT 352
           +S  P     H+ P +   ++L     A+G  +    +  +  S ++             
Sbjct: 570 SSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTRSPHTTLSPAGSTTRQGE 629

Query: 353 SSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIH 412
           S++F S PS+    P+P T TS +  P   +  SPS   + H         L       H
Sbjct: 630 STTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYH 689

Query: 413 VLRNHAVGPSTSLPAGHSDIHSLLG----PSHNAPIGSLNSNYGGSSLVASSRSASMVGT 468
                + G + ++    SD  S  G     SH++   +++S        A S ++++V  
Sbjct: 690 ----SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS--------APSTTSALV-- 735

Query: 469 HREDSVSLNGNHSVLSSTVTT----SSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKE 524
             E+  S    HS   ST TT    SST      +       Q  +GT+V     T +  
Sbjct: 736 --EEPTSY---HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTNSVL 790

Query: 525 KDENLHEPPSSDDMKS 540
             E+   P SS  M++
Sbjct: 791 LGESTTSPISSGSMET 806



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 83/359 (23%), Positives = 128/359 (35%), Gaps = 36/359 (10%)

Query: 56  GTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL-------GAHEGLSPTPFMNSNLM 108
           GTT+  + G  S ++ SS G+T +    D+   S L        +  G   T    S+  
Sbjct: 209 GTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSST 268

Query: 109 GKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSAT---SSR 165
               E  +F  +          S      + L +    S S  P T + + S T   S  
Sbjct: 269 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 328

Query: 166 RRPLHDSAALDPLQAKKVRKVPPG--LPSSVYAPSPNSDD---FNRESPSYPSPKPPTSM 220
             P+H S           R    G    S+ Y  SP S     F   S +    +   + 
Sbjct: 329 STPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATF 388

Query: 221 FASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILG-TSTSHMSQSSSYGNLHSHDRLSYPP 279
             ST      TH  S   S++  ++   +   LG T T+H   SS+        + S   
Sbjct: 389 HGST------THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKAS--- 439

Query: 280 HSVSPTDINTSLPPMS--SFHRGSTSSSPYVAAS-HTPPINGSDSILGTRGNAAGSSQTG 336
           HS       T LP  S  S   G ++ SP  + S  T  + GS     T+   +  S T 
Sbjct: 440 HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST----TKPGLSEKSTTF 495

Query: 337 DALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWP----RPGGQAPSSPSYEN 391
            +  ++  + + P   +SS  S  ST   S    T T+ +P     PG    S+ S+ +
Sbjct: 496 YSSPRSPDTTHLPARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 554



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 73/354 (20%), Positives = 129/354 (36%), Gaps = 28/354 (7%)

Query: 161 ATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPS-YPSPKPPTS 219
           AT +   P H + ++   + K        + ++    S  +   + +S + Y SP+ P  
Sbjct: 89  ATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 148

Query: 220 MFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPP 279
             +       G    S     +   S+PG    +    S      S  +  SH       
Sbjct: 149 TLSPARTTSSGVSEKS-----TTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTD 203

Query: 280 HSVSP-TDINTSLPPMSS-FHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGD 337
            ++SP T   +SL P S+ FH     SSP    +   P N + S L        SS    
Sbjct: 204 TTLSPGTTTPSSLGPESTTFH-----SSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSP 258

Query: 338 ALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQ 397
               + +S  + +   ++F S PS+   SP+P   TS + +      SSPS   + H   
Sbjct: 259 HTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSA 318

Query: 398 SRMEDRLDRLDDAIH---VLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGS 454
           S            +H   V       P+ S  +GH +  +     H +P         GS
Sbjct: 319 SSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAY---HRSP---------GS 366

Query: 455 SLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQS 508
           +       +S    H E+S + +G+ +   S+  +++  L H +  +  G  ++
Sbjct: 367 TQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTET 420


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 127/556 (22%), Positives = 212/556 (38%), Gaps = 70/556 (12%)

Query: 24  SAMFSPPVNSGKTRP-----TTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTD 78
           S+  + P  SG T       TT  SS  S         +T+ G S + +P + S      
Sbjct: 347 SSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATAT 406

Query: 79  SPH-----YSDHLNDSRLGAHEGLSPTPFMN----SNLMGKTSERGSFSLYSRDTGLPGC 129
           +P       S H+ +S    H     T  M+    S   G + E  +F   +  T     
Sbjct: 407 TPPPARSATSGHVEEST-AYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHT----- 460

Query: 130 QSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPG 189
           +SS       L   +  SS G   T ++  S+T S R     ++   P  A     +P G
Sbjct: 461 KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP-DAMATTVLPAG 519

Query: 190 LPSSVYA----PSPNSDDFNRESPSYP--SPKPPTSMFASTFFMQDGTHNSSDLWSS--S 241
              SV      PSP S   + E+ + P  + KP  S  ++TF+    + +++ L +S  S
Sbjct: 520 STPSVLVGDSTPSPISSG-SMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTS 578

Query: 242 NGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGS 301
           +G+S+          ++H +       +    + S   HS SP   +T+L P S+    +
Sbjct: 579 SGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS-SPGPTDTTLSPGSTT---A 634

Query: 302 TSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSP---------DHT 352
           +S  P     H+ P +   ++L     A+G  +    +  +  S ++             
Sbjct: 635 SSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGE 694

Query: 353 SSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIH 412
           S++F S PS+    P+P T TS +  P   +  SPS   + H         L       H
Sbjct: 695 STTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYH 754

Query: 413 VLRNHAVGPSTSLPAGHSDIHSLLG----PSHNAPIGSLNSNYGGSSLVASSRSASMVGT 468
                + G + ++    SD  S  G     SH++   +++S        A S ++++V  
Sbjct: 755 ----SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS--------APSTTSALV-- 800

Query: 469 HREDSVSLNGNHSVLSSTVTT----SSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKE 524
             E+  S    HS   ST TT    SST      +       Q  +GT+V     T +  
Sbjct: 801 --EEPTSY---HSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVL 855

Query: 525 KDENLHEPPSSDDMKS 540
             E+   P SS  M++
Sbjct: 856 LGESTTSPISSGSMET 871



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 119/549 (21%), Positives = 194/549 (35%), Gaps = 100/549 (18%)

Query: 69   SYDSSRGFTDSPHYSDHLNDS-----RLGAHEG-------LSPTPFMNSNLMGKTSERGS 116
            SY SS G T + H+ D    S      + +H         + P    NS L+G+++    
Sbjct: 805  SYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPI 864

Query: 117  FSLYSRDTGLPGCQS------------SLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSS 164
             S     T LPG  +            S  R      SPA  +SSG       S  +T+S
Sbjct: 865  SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSG------VSEESTTS 918

Query: 165  RRRP--LHDSAALDPLQAKKVRK------VPPGLPSSVYAPSPNSDDFNRESPSYPSPKP 216
              RP   H +A  D      + +        PG   +   P+  +     E  + P    
Sbjct: 919  HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSG 978

Query: 217  PTSMFA--------------STFFMQDGTHNS--SDLWSSSNGMSQPGFGGILGTSTSHM 260
             T   A              +TF+    + ++  S   ++S+G+S+          ++H 
Sbjct: 979  STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 1038

Query: 261  SQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSD 320
            +       +    + S   HS SP   +T+L P S+    ++S  P     H+ P +   
Sbjct: 1039 TAFPGSTTMPGVSQESTASHS-SPGSTDTTLSPRSTT---ASSLGPESTTFHSGPGSTET 1094

Query: 321  SILGTRGNAAG----SSQTGDALGKALASIYSPDHT-----SSSFPSNPSTPVGSPSPLT 371
            ++L     A+G    S+    + G    ++     T     S++F S PS+    P+P T
Sbjct: 1095 TLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPT 1154

Query: 372  GTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSD 431
             TS +      +  SPS   + H   S            +H   +  V P+T+     S 
Sbjct: 1155 TTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVH---SSPVAPATTPSPARST 1211

Query: 432  IHSLLGPS---HNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVT 488
               L+  S   H++P GS  + +   S  AS RS        E   S +     +SS  +
Sbjct: 1212 TSGLVEESTAYHSSP-GSTQTMHFPESSTASGRS-------EESRTSHSSTTHTISSPPS 1263

Query: 489  TSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKD 548
            T+S  +   T         S  G++ TT             H P SS      +ES+   
Sbjct: 1264 TTSALVEEPT------SYHSSPGSIATT-------------HFPESSTTSGRSEESTASH 1304

Query: 549  IKVSSRGRT 557
                + G T
Sbjct: 1305 SSPDTNGIT 1313



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 84/361 (23%), Positives = 131/361 (36%), Gaps = 40/361 (11%)

Query: 56  GTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSP------TPFMNSNLMG 109
           GTT+  + G  S ++ SS G+T +    D  N +  G  E  +P      +P    +   
Sbjct: 274 GTTTPSSLGPESTTFHSSPGYTKTTRLPD--NTTTSGLLEASTPVHSSTGSPHTTLSPAS 331

Query: 110 KTSERG---SFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSAT---S 163
            T+  G   +F  +          S      + L +    S S  P T + + S T   S
Sbjct: 332 STTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHS 391

Query: 164 SRRRPLHDSAALDPLQAKKVRKVPPG--LPSSVYAPSPNSDD---FNRESPSYPSPKPPT 218
               P+H S           R    G    S+ Y  SP S     F   S +    +   
Sbjct: 392 EESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESA 451

Query: 219 SMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILG-TSTSHMSQSSSYGNLHSHDRLSY 277
           +   ST      TH  S   S++  ++   +   LG T T+H   SS+        + S 
Sbjct: 452 TFHGST------THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKAS- 504

Query: 278 PPHSVSPTDINTSLPPMS--SFHRGSTSSSPYVAAS-HTPPINGSDSILGTRGNAAGSSQ 334
             HS       T LP  S  S   G ++ SP  + S  T  + GS     T+   +  S 
Sbjct: 505 --HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST----TKPGLSEKST 558

Query: 335 TGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWP----RPGGQAPSSPSYE 390
           T  +  ++  + + P   +SS  S  ST   S    T T+ +P     PG    S+ S+ 
Sbjct: 559 TFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHS 618

Query: 391 N 391
           +
Sbjct: 619 S 619



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 74/354 (20%), Positives = 129/354 (36%), Gaps = 28/354 (7%)

Query: 161 ATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPS-YPSPKPPTS 219
           AT +   P H + ++   + K        + ++    S  +   + +S + Y SP+ P  
Sbjct: 154 ATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDR 213

Query: 220 MFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPP 279
             +       G    S     +   S+PG    +    S      S  +  SH       
Sbjct: 214 TLSPARTTSSGVSEKS-----TTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTD 268

Query: 280 HSVSP-TDINTSLPPMSS-FHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGD 337
            ++SP T   +SL P S+ FH     SSP    +   P N + S L        SS    
Sbjct: 269 TTLSPGTTTPSSLGPESTTFH-----SSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSP 323

Query: 338 ALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQ 397
               + AS  + +   ++F S PS+   SP+P   TS + +      SSPS   + H   
Sbjct: 324 HTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSA 383

Query: 398 SRMEDRLDRLDDAIH---VLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGS 454
           S            +H   V       P+ S  +GH +  +     H +P         GS
Sbjct: 384 SSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAY---HRSP---------GS 431

Query: 455 SLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQS 508
           +       +S    H E+S + +G+ +   S+  +++  L H +  +  G  ++
Sbjct: 432 TQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTET 485


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 96/379 (25%), Positives = 135/379 (35%), Gaps = 72/379 (18%)

Query: 27   FSPPVNSGKTRPTTLGSSQFSGSGIDERGG-----TTSW----GTSGQPSPS--YDSSRG 75
            +SP V SG T     G++ FS S   +  G     + +W    G+ G P PS  Y  S G
Sbjct: 1531 WSPSVGSGMTP----GAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPG 1586

Query: 76   FTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLR 135
               SP YS         A+E  SP         G T +  S+S  S          S   
Sbjct: 1587 GAMSPSYSP-----TSPAYEPRSPG--------GYTPQSPSYSPTSPSYSPTSPSYSPTS 1633

Query: 136  QDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDS-AALDPLQAKKVRKVPPGLPSSV 194
             +    SP+   +S        S+S TS    P   S +   P  +       P  PS  
Sbjct: 1634 PNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY- 1692

Query: 195  YAPSPNSDDFNRESPSY----PSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFG 250
               SP S  ++  SPSY    PS  P +  ++ T      T  S    S S   + P + 
Sbjct: 1693 ---SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYS 1749

Query: 251  GILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAA 310
                TS ++   S SY    S    SY P S + T  + +  P S  +  ++ S    + 
Sbjct: 1750 ---PTSPNYTPTSPSY----SPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSP 1802

Query: 311  SHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPL 370
            S++P                              +  SP +T SS   +PS+P  SP   
Sbjct: 1803 SYSP-------------------------SSPRYTPQSPTYTPSSPSYSPSSPSYSP--- 1834

Query: 371  TGTSQWPRPGGQAPSSPSY 389
            T     P     +PSSP Y
Sbjct: 1835 TSPKYTPTSPSYSPSSPEY 1853



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 66/258 (25%), Positives = 101/258 (39%), Gaps = 19/258 (7%)

Query: 142  SPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNS 201
            SPA   + G PG+   S     S    +  S +  P       + P G      + SP S
Sbjct: 1562 SPAWSPTPGSPGSPGPSSPYIPSPGGAM--SPSYSPTSPAYEPRSPGGYTPQSPSYSPTS 1619

Query: 202  DDFNRESPSY----PSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTST 257
              ++  SPSY    P+  P +  ++ T      T  S    S S   + P +     TS 
Sbjct: 1620 PSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSP 1676

Query: 258  SHMSQSSSYGNL---HSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTP 314
            S+   S SY      +S    SY P S S +  + S  P S  +  ++ S    + S++P
Sbjct: 1677 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1736

Query: 315  PINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTS 374
                S S   T  N + +S        + +   SP ++ +S    P++P  SP   T  S
Sbjct: 1737 T---SPSYSPTSPNYSPTSPNYTPTSPSYSPT-SPSYSPTSPNYTPTSPNYSP---TSPS 1789

Query: 375  QWPRPGGQAPSSPSYENS 392
              P     +P+SPSY  S
Sbjct: 1790 YSPTSPSYSPTSPSYSPS 1807



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 36/117 (30%), Positives = 55/117 (47%), Gaps = 17/117 (14%)

Query: 283  SPTDINTSLPPMSSFHRGSTSS----SPYVAASHTPPINGSDSILGTRGNAAGSSQTGDA 338
            +P+ +    P M+ +++G+T +    SP V +  TP   G          +A S  +G +
Sbjct: 1506 APSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSP-------SAASDASGFS 1558

Query: 339  LGKALASIYSPDHTSSSFPSNP--STPVGSPSPL---TGTSQWPR-PGGQAPSSPSY 389
             G + A   +P    S  PS+P   +P G+ SP    T  +  PR PGG  P SPSY
Sbjct: 1559 PGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSY 1615


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 123/551 (22%), Positives = 204/551 (37%), Gaps = 71/551 (12%)

Query: 38   PTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGL 97
            PTT  SSQ S       G TT+  + GQ S ++ SS G T++    D    S  G  E  
Sbjct: 983  PTTSHSSQGSTEATLSPGSTTA-SSLGQQSTTFHSSPGDTETTLLPDDTITS--GLVEAS 1039

Query: 98   SPTPFMNSNLMGKTSERGSFS--LYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTA 155
            +PT     +L    +   S S  L    T      SS    D     P   ++  +  T 
Sbjct: 1040 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS---SDTTPSPPGTTAAPVEVSTT 1096

Query: 156  YYS---------FSATSSRRRPLHDSAALDPLQ-AKKVRKVPPGLPSSVYAPSPNSDDFN 205
            Y+S         FSA+S+      +S  +     A      P    +SV    P +   +
Sbjct: 1097 YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS 1156

Query: 206  R---ESPSYPSPKPPTSMF--ASTFFMQDGTHNS--SDLWSSSNGMSQPGFGGILGTSTS 258
                E+ + P       +   ++TF+    + ++  S   ++S+G+S+          ++
Sbjct: 1157 SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGST 1216

Query: 259  HMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPING 318
            H +       +    + S   HS SP   +T+L P S+    ++S  P     H+ P + 
Sbjct: 1217 HTTAFPGSTTMPGVSQESTASHS-SPGSTDTTLSPGSTT---ASSLGPESTTFHSSPGST 1272

Query: 319  SDSILGTRGNAAGSSQTGDALGKALASIYSP---------DHTSSSFPSNPSTPVGSPSP 369
              ++L     A+G  +    +  +  S ++             S++F S PS+    P+P
Sbjct: 1273 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1332

Query: 370  LTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGH 429
             T TS +      +  SPS   + H   S     L R +++  V  +     +T  PA  
Sbjct: 1333 PTTTSAFVELSTTSHGSPSSTPTTHF--SASSTTLGRSEESTTVHSSPVATATTPSPA-R 1389

Query: 430  SDIHSLLGPS---HNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSST 486
            S    L+  S   H++P GS  + +   S  AS RS        E   S +     +SS 
Sbjct: 1390 STTSGLVEESTAYHSSP-GSTQTMHFPESSTASGRS-------EESRTSHSSTTHTISSP 1441

Query: 487  VTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQ 546
             +T+S  +   T         S  G++ TT             H P SS      +ES+ 
Sbjct: 1442 PSTTSALVEEPT------SYHSSPGSIATT-------------HFPESSTTSGRSEESTA 1482

Query: 547  KDIKVSSRGRT 557
                  + G T
Sbjct: 1483 SHSSPDTNGIT 1493



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 105/462 (22%), Positives = 180/462 (38%), Gaps = 55/462 (11%)

Query: 104 NSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATS 163
           +S   G + E  +F   +  T     +SS       L   +  SS G   T ++  S+T 
Sbjct: 6   SSTTSGHSEESATFHGSTTHT-----KSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTI 60

Query: 164 SRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYA----PSPNSDDFNRESPSYP--SPKPP 217
           S R     ++   P  A     +P G   SV      PSP S   + E+ + P  + KP 
Sbjct: 61  SGRSEESKASHSSP-DAMATTVLPAGSTPSVLVGDSTPSPISSG-SMETTALPGSTTKPG 118

Query: 218 TSMFASTFFMQDGTHNSSDLWSS--SNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRL 275
            S  ++TF+    + +++ L +S  S+G+S+          ++H +       +    + 
Sbjct: 119 LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQE 178

Query: 276 SYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQT 335
           S   HS SP   +T+L P S+    ++S  P     H+ P +   ++L     A+G  + 
Sbjct: 179 STASHS-SPGPTDTTLSPGSTT---ASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEA 234

Query: 336 GDALGKALASIYSP---------DHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSS 386
              +  +  S ++             S++F S PS+    P+P T TS +  P   +  S
Sbjct: 235 SMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGS 294

Query: 387 PSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLG----PSHNA 442
           PS   + H         L       H     + G + ++    SD  S  G     SH++
Sbjct: 295 PSSIPTTHISARSTTSGLVEESTTYH----SSPGSTQTMHFPESDTTSGRGEESTTSHSS 350

Query: 443 PIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTT----SSTDLNHKT 498
              +++S        A S ++++V    E+  S    HS   ST TT    SST      
Sbjct: 351 TTHTISS--------APSTTSALV----EEPTSY---HSSPGSTATTHFPDSSTTSGRSE 395

Query: 499 QENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKS 540
           +       Q  +GT+V     T +    E+   P SS  M++
Sbjct: 396 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 437



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 123/588 (20%), Positives = 205/588 (34%), Gaps = 91/588 (15%)

Query: 32   NSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL 91
            +S ++  TTL  +  + SG+ E   T+        + ++  S   T +P  S H   S  
Sbjct: 458  SSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDS---TTTPGLSRHSTTSH- 513

Query: 92   GAHEGLSPTPFMNSNLM----GKTSERGSFSLYSRDTGL-PGCQSSLLRQDLGLGSPAQL 146
             +  G + T  + ++       + S     S  S DT L PG  ++L     G  S    
Sbjct: 514  -SSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTAL---SFGQESTTFH 569

Query: 147  SSSGKPGTAYYSFSATSS----RRRPLHDSAALDPLQAKKVRKVPPGL------------ 190
            S+ G   T  +  S TSS        +H S               PGL            
Sbjct: 570  SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 629

Query: 191  --------PSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSN 242
                    PS+  AP   S  ++R   S P+   P S   S      G    S ++ SS 
Sbjct: 630  STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS------GHSEKSTIFHSSP 683

Query: 243  GMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGST 302
              S         T++     ++S  +  S +  + P  + +P     S    SS    +T
Sbjct: 684  DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 743

Query: 303  SSSPYVAASHTPPINGSDSIL------GTRGNAAGSSQTGDALGKALASIYSPDHTSSS- 355
            + SP   AS T    G +S         T    + +S T   L +   ++YS    S+  
Sbjct: 744  TLSP---ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTET 800

Query: 356  --FPSNPSTPVGSPSPLTGTS-----------QWPRPGGQAPSSPSYENSLHSLQSRMED 402
              FP + +T V    P T  S           +     G    S ++  S  S Q+ +  
Sbjct: 801  TVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 860

Query: 403  RLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRS 462
             L   D             ST+ P+      + L P+ +   G +  +       +S+ +
Sbjct: 861  TLTTAD---------LGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 911

Query: 463  ASMVGTHREDSVSLNGNHSVLS--------STVTTSSTDLNHKTQENYRGGLQSQSGTVV 514
             ++ G+    S+S        S        S  TT+S+ ++ ++  ++     SQ G+  
Sbjct: 912  TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSH-----SQPGSTH 966

Query: 515  TTEIKTENKEKDENLHEPPSSDDMKSDDES--SQKDIKVSSRGRTSST 560
            TT         D +  EP +S   +   E+  S      SS G+ S+T
Sbjct: 967  TTAFPDSTTTSDLS-QEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 1013


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 109/476 (22%), Positives = 171/476 (35%), Gaps = 79/476 (16%)

Query: 66  PSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTG 125
           PSPS+DS+   T                  GL P P M    +  T  +   +L +  T 
Sbjct: 233 PSPSFDSNPPTTLL----------------GLIPAPSM----VPATDTKAPPTLQAETTT 272

Query: 126 LPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSA-TSSRRRPLHDSAALDPLQAKKVR 184
            P   S+         +P Q    G   T+  S +A  +S   P+       P +++K  
Sbjct: 273 KPQATSA------PSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEG 326

Query: 185 KVPPG------LPSSVYAPSPNSDDFNRESPSYPSPKPPTSM-FASTFFMQDGTHNSSDL 237
             PPG       PSS   P+  S       P + S  PP S+   + FF Q  T  ++  
Sbjct: 327 PTPPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPT 386

Query: 238 WS----------------------SSNGMSQPGFG-GILGTSTSHMSQSSSYGNLHSHDR 274
            +                      S++  S+P FG GI   S+S +S ++S     S   
Sbjct: 387 TTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPF 446

Query: 275 LSYPPHS--VSPTDINTSL-----PP-------MSSFHRGSTSSSPYVAASHTPPINGSD 320
           L   P +   S T    S+     PP       +++F +   ++ P   +S     +G  
Sbjct: 447 LFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFG 506

Query: 321 SILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPG 380
           S L T   A  S  T      +  +   P  +S+  P  PS P  +P P  G ++   PG
Sbjct: 507 STLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPL-PSYPGANPQPAFGAAEGQPPG 565

Query: 381 GQAPS-SPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLG-- 437
              P+ +PS+ +S     S              +    A  P+   P      HS  G  
Sbjct: 566 AAKPALTPSFGSSFTFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLK 625

Query: 438 ---PSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTS 490
               +  AP  S    +GGS+ V S  +A+  G       + +G+ S +  + T S
Sbjct: 626 ATASAFGAPASS-QPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS 680


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 94/404 (23%), Positives = 150/404 (37%), Gaps = 59/404 (14%)

Query: 142 SPAQLSSSGKPGTAYYSFSA-TSSRRRPLHDSAALDPLQAKKVRKVPPG------LPSSV 194
           +P Q    G   T+  S +A  +S   P+       P +++K    PPG       PSS 
Sbjct: 434 APKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSS 493

Query: 195 YAPSPNSDDFNRESPSYPSPKPPTSM-FASTFFMQDGTHNSSDLWS-------------- 239
             P+  S       P + S  PP S+   + FF Q  T  ++   +              
Sbjct: 494 SLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAV 553

Query: 240 --------SSNGMSQPGFG-GILGTSTSHMSQSSSYGNLHSHDRLSYPPHS--VSPTDIN 288
                   S++  S+P FG GI   S+S +S ++S     S   L   P +   S T   
Sbjct: 554 APITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAM 613

Query: 289 TSL-----PP-------MSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTG 336
            S+     PP       +++F +   ++ P   +S     +G  S L T   A  S  T 
Sbjct: 614 GSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSAPATSSQPTL 673

Query: 337 DALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPS-SPSYENSLHS 395
                +  +   P  +S+  P  PS P  +P P  G ++   PG   P+ +PS+ +S   
Sbjct: 674 TFSNTSTPTFNIPFGSSAKSPL-PSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTF 732

Query: 396 LQSRMEDRLDRLDDA----IHVLRNHAVGPSTSLPAGHSDIHSLLG-----PSHNAPIGS 446
             S           A    I ++  H   P+   P      HS  G      +  AP  S
Sbjct: 733 GNSAAPAPATAPTPAPASTIKIVPAHV--PTPIQPTFGGATHSAFGLKATASAFGAPASS 790

Query: 447 LNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTS 490
               +GGS+ V S  +A+  G       + +G+ S +  + T S
Sbjct: 791 -QPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPS 833



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 73/351 (20%), Positives = 124/351 (35%), Gaps = 74/351 (21%)

Query: 38  PTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSR---LGAH 94
           PT   SS    SG      T++  TS QP+ ++ +    T +P ++     S    L ++
Sbjct: 643 PTATSSSAADFSGFGSTLATSAPATSSQPTLTFSN----TSTPTFNIPFGSSAKSPLPSY 698

Query: 95  EGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGT 154
            G +P P                +  + +   PG     L    G       S++  P T
Sbjct: 699 PGANPQP----------------AFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPAT 742

Query: 155 AYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSP 214
           A     A++ +  P H    + P           G   S +     +  F   + S P+ 
Sbjct: 743 APTPAPASTIKIVPAHVPTPIQPTFG--------GATHSAFGLKATASAFGAPASSQPAF 794

Query: 215 KPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDR 274
              T++F+       G   SS   +++   S      + G++T       ++G       
Sbjct: 795 GGSTAVFSF------GAATSSGFGATTQTASSGSSSSVFGSTT---PSPFTFGG------ 839

Query: 275 LSYPPHSVSPTDINTSLPPMS------SFHRGSTSSSPYVAASHTPPINGSDSILGTRGN 328
            S  P       IN + P  S      SF  G + S+    A+ TP   G    LG   N
Sbjct: 840 -SAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGST----ATSTPFTGG----LGQ--N 888

Query: 329 AAGSSQTGDALGKALASIYSPDHTSSSFP-----SNPSTPVGSPSPLTGTS 374
           A G++      G++    ++   T+ S P     + P+    +P+P  GTS
Sbjct: 889 ALGTT------GQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTS 933


>gi|57864582 hornerin [Homo sapiens]
          Length = 2850

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 114/498 (22%), Positives = 159/498 (31%), Gaps = 74/498 (14%)

Query: 42   GSSQFSG-----SGIDERGGTTSWGTSGQPSPSYD-----SSRGFTDSPHYSDHLNDSRL 91
            GSSQ SG     SG  +  G    G+  + SPSY      S R  +   H S     S  
Sbjct: 1108 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGF 1167

Query: 92   GAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGK 151
            G HE        +S      S+ GS S +S   G  G +S       G  S  +   S  
Sbjct: 1168 GHHES-------SSGQSSSYSQHGSGSGHSSGYGQHGSRS-------GQSSRGERHGSSS 1213

Query: 152  PGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLP-SSVYAPSPNSDDFNRESPS 210
              +++Y    + SR+   H         +    +   GL  SS +    +    +     
Sbjct: 1214 GSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGP 1273

Query: 211  YPSPKPPTSMFA--------STFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQ 262
            Y S    +S+F         S+ + Q G+  S    S     S  G         S   Q
Sbjct: 1274 YESRSGHSSVFGQHESGSGHSSAYSQHGS-GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQ 1332

Query: 263  SSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSI 322
            SSSYG+  S    S                  S + R    S    +       +G  S 
Sbjct: 1333 SSSYGHRGSGSSQS------------------SGYGRHGAGSGQSPSRGRHGSGSGHSSS 1374

Query: 323  LGTRGNAAGSSQTGDALGKALA-SIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGG 381
             G  G+ +G S +    G     S     H SSS+ S+  T  GS              G
Sbjct: 1375 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS--------------G 1420

Query: 382  QAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPS-- 439
               SS   ++   S QS   +R      +      H  G   SL  G     S   PS  
Sbjct: 1421 SGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPS 1480

Query: 440  ---HNAPIG--SLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDL 494
               H +  G  S  S YG  S  +SSR     G+     +    + S  SS      +  
Sbjct: 1481 RGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSS 1540

Query: 495  NHKTQENYRGGLQSQSGT 512
             H +     G    QS +
Sbjct: 1541 GHSSTHGQHGSTSGQSSS 1558



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 111/494 (22%), Positives = 159/494 (32%), Gaps = 66/494 (13%)

Query: 42   GSSQFSG-----SGIDERGGTTSWGTSGQPSPSYD-----SSRGFTDSPHYSDHLNDSRL 91
            GSSQ SG     SG  +  G    G+  + SPSY      S R  +   H       S  
Sbjct: 2048 GSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGF 2107

Query: 92   GAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGK 151
            G HE        +S      S+ GS S +S   G  G +S       G  S  +   S  
Sbjct: 2108 GHHES-------SSGQSSSYSQHGSGSGHSSGYGQHGSRS-------GQSSRGERHGSSS 2153

Query: 152  PGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSY 211
              ++ Y    + SR+   H         +    +   G   S ++ S           S 
Sbjct: 2154 GSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSG---SGHSSSHGQHGSGSGRSSS 2210

Query: 212  PSPKPPTSMFASTFFMQDGTHNSSDLWS-----SSNGMSQPGFGGILGTSTSHMSQSSSY 266
              P    S  +S F   +     S  +S     S +  SQ   G   G S++   + SS 
Sbjct: 2211 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2270

Query: 267  GNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTR 326
            G   SH +     H    +         SS+ +  + S    +       +G  S  G  
Sbjct: 2271 GQSSSHGQ-----HGSGSSQ-------SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQH 2318

Query: 327  GNAAGSSQTGDALGKALA-SIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPS 385
            G+ +G S +    G     S     H SSS+ S+  T  GS              G   S
Sbjct: 2319 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS--------------GSGHS 2364

Query: 386  SPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPS-----H 440
            S   ++   S QS   +R      +      H  G   SL  G     S   PS     H
Sbjct: 2365 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRH 2424

Query: 441  NAPIG--SLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKT 498
             +  G  S  S YG  S  +SSR     G+     +    + S  SS      +   H +
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 2484

Query: 499  QENYRGGLQSQSGT 512
                 G    QS +
Sbjct: 2485 THGQHGSTSGQSSS 2498



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 119/517 (23%), Positives = 162/517 (31%), Gaps = 83/517 (16%)

Query: 39   TTLGSSQFSGSGIDERGGTTSWGT-----------------SGQPSPSYDSSRGFTDSPH 81
            +T G S  SG      G ++S+G                  SGQ         G   SP 
Sbjct: 846  STSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPS 905

Query: 82   YSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLG 141
            Y  H + S   +  G   +    S+  G  S  G  S Y++     G  SS  +     G
Sbjct: 906  YGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSG 965

Query: 142  SPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNS 201
              ++    G         S+ SS     H S +   L                       
Sbjct: 966  QSSRSEQHGS--------SSGSSSSYGQHGSGSRQSL---------------------GH 996

Query: 202  DDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFG--GILGTSTSH 259
                  S   PSP        S      G + S   WSSS G  + G G    LG   S 
Sbjct: 997  GQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056

Query: 260  MSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGS 319
              QSS YG   S    S    S      +TS    S    G++S     ++SH    +GS
Sbjct: 1057 SGQSSGYGQHGSSSGHS----STHGQHGSTSGQSSSCGQHGASSGQ---SSSHGQHGSGS 1109

Query: 320  DSILGTRGNAAGSSQTGDALGKALASIYSPD---HTSSSFPSNPSTPVGS---------- 366
                G     +GS Q+     +   S  SP    H S S  S+ S   GS          
Sbjct: 1110 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1169

Query: 367  -PSPLTGTSQWPRPGGQAPSSPSY-ENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTS 424
              S    +S + + G  +  S  Y ++   S QS   +R      +      H  G   S
Sbjct: 1170 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQS 1229

Query: 425  LPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVL- 483
              +GH    S  G  H+   G   S  G SS      S S   + R    S +G+ SV  
Sbjct: 1230 --SGHGRQGS--GSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG 1285

Query: 484  --------SSTVTTSSTDLNHKTQENYRGGLQSQSGT 512
                    SS  +   +   H   +   G    QS T
Sbjct: 1286 QHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSST 1322



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 110/462 (23%), Positives = 157/462 (33%), Gaps = 69/462 (14%)

Query: 43   SSQFS--GSGIDERGGTTSWGT-SGQPSPSYDSSRGFTDSPHYSDHLNDSRL-------G 92
            SS +S  GSG     G    G+ SGQ S           S HY  H + SR        G
Sbjct: 1177 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG 1236

Query: 93   AHEGLSPTPFMNSNLMGKTS---ERGSFSLYSRDTG----LPGCQSSLLRQDLGLGSPAQ 145
            +  G SP+   + + +G +S   + GS S  S   G      G  S   + + G G  + 
Sbjct: 1237 SGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSA 1296

Query: 146  LSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFN 205
             S  G  G+ +  F +          S+  D   +   +    G   S    S  S  + 
Sbjct: 1297 YSQHGS-GSGH--FCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS---GSSQSSGYG 1350

Query: 206  RESP-SYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSS 264
            R    S  SP        S      G H S   WSSS+G    G G           QSS
Sbjct: 1351 RHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG-----------QSS 1399

Query: 265  SYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILG 324
             +G+   H+  S+   S   T   +     SS+ +  + S            +GS S  G
Sbjct: 1400 GFGH---HESSSW--QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYG 1454

Query: 325  TRGNAAGSSQTGDALGKALASIYSPD---HTSSSFPSNPSTPVGSPSPLTGTSQWPRPGG 381
              G+ +  S      G       SP    H S S  S+  +P GS       S W    G
Sbjct: 1455 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGS------GSGWSSSRG 1508

Query: 382  QAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHN 441
               S  S+ + L   +SR               ++   G   S  +GHS  H      H 
Sbjct: 1509 PYESGSSHSSGLGHRESRSG-------------QSSGYGQHGS-SSGHSSTHG----QHG 1550

Query: 442  APIGSLNS--NYGGSSLVASSRSASMVGTHREDSVSLNGNHS 481
            +  G  +S   +G SS  +SS      G+ +       G+ S
Sbjct: 1551 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 1592



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 108/461 (23%), Positives = 155/461 (33%), Gaps = 67/461 (14%)

Query: 43   SSQFS--GSGIDERGGTTSWGT-SGQPSPSYDSSRGFTDSPHYSDHLNDSRL-------G 92
            SS +S  GSG     G    G+ SGQ S           S  Y  H + SR        G
Sbjct: 1647 SSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQG 1706

Query: 93   AHEGLSPTPFMNSNLMGKTS---ERGSFSLYSRDTG----LPGCQSSLLRQDLGLGSPAQ 145
            +  G SP+   + + +G +S   + GS S  S   G      G  S   + + G G  + 
Sbjct: 1707 SGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSA 1766

Query: 146  LSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFN 205
             S  G  G+ +  F +          S+  D   +   +    G   S    S +S    
Sbjct: 1767 YSQHGS-GSGH--FCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS--GSSQSSSYGQ 1821

Query: 206  RESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSS 265
            + S S  SP        S      G H S   WSSS+G    G G           QSS 
Sbjct: 1822 QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG-----------QSSG 1870

Query: 266  YGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGT 325
            +G+   H+  S+   S   T   +     SS+ +  + S            +GS S  G 
Sbjct: 1871 FGH---HESSSW--QSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQ 1925

Query: 326  RGNAAGSSQTGDALGKALASIYSPD---HTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQ 382
             G+ +  S      G       SP    H S S  S+   P GS       S W    G 
Sbjct: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGS------GSGWSSSRGP 1979

Query: 383  APSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNA 442
              S   + + L   +SR               ++   G   S  +GHS  H      H +
Sbjct: 1980 YESGSGHSSGLGHRESRSG-------------QSSGYGQHGS-SSGHSSTHG----QHGS 2021

Query: 443  PIGSLNS--NYGGSSLVASSRSASMVGTHREDSVSLNGNHS 481
              G  +S   +G SS  +SS      G+ +       G+ S
Sbjct: 2022 ASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2062



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 102/446 (22%), Positives = 152/446 (34%), Gaps = 59/446 (13%)

Query: 44   SQFSGSGIDERGGTTSWGTS--GQPSPSYDSSRGFTDSPHYSDHL-NDSRLGAHEGLSPT 100
            S+   S   ER G++S  +S  GQ       S G       S H  +  R G+  G S +
Sbjct: 2138 SRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSS 2197

Query: 101  PFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFS 160
               + +  G++S RG +   S  + + G   S      G G  +  S  G  G+ +  F 
Sbjct: 2198 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHES------GSGHSSAYSQHGS-GSGH--FC 2248

Query: 161  ATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSM 220
            +          S+  D   +   +    G   S    S +S    + S S  SP      
Sbjct: 2249 SQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGS--GSSQSSSYGQQGSGSGQSPSRGRHG 2306

Query: 221  FASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPH 280
              S      G H S   WSSS+G    G G           QSS +G+   H+  S+   
Sbjct: 2307 SGSGHSSSYGQHGSGSGWSSSSGRHGSGSG-----------QSSGFGH---HESSSW--Q 2350

Query: 281  SVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALG 340
            S   T   +     SS+ +  + S            +GS S  G  G+ +  S      G
Sbjct: 2351 SSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHG 2410

Query: 341  KALASIYSPD---HTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQ 397
                   SP    H S S  S+  +P GS       S W    G   S   + + L   +
Sbjct: 2411 SGSGQSPSPSRGRHGSGSGQSSSYSPYGS------GSGWSSSRGPYESGSGHSSGLGHRE 2464

Query: 398  SRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNS--NYGGSS 455
            SR               ++   G   S  +GHS  H      H +  G  +S   +G SS
Sbjct: 2465 SRSG-------------QSSGYGQHGS-SSGHSSTHG----QHGSTSGQSSSCGQHGASS 2506

Query: 456  LVASSRSASMVGTHREDSVSLNGNHS 481
              +SS      G+ +       G+ S
Sbjct: 2507 GQSSSHGQHGSGSSQSSGYGRQGSGS 2532



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 122/506 (24%), Positives = 157/506 (31%), Gaps = 98/506 (19%)

Query: 47   SGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSN 106
            SGS    R G    G+   PS     S  F  S  Y  H + S   +  G   +    S+
Sbjct: 641  SGSSQSSRYGQQGSGSGQSPSRGRHGS-DFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSS 699

Query: 107  LMGKTSERGSFSLYS------------RDTGLPGCQSSLLRQDLGLGSPAQLSSS-GKPG 153
              G  S  G  S YS            R  G    QSS   Q    GS + LSSS G+ G
Sbjct: 700  GFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQH---GSSSGLSSSYGQHG 756

Query: 154  TAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPS 213
            +  +  S    +      S +       +VR       SS +    +    +     Y S
Sbjct: 757  SGSHQSSGHGRQGSGSGHSPS-------RVRHGSSSGHSSSHGQHGSGTSCSSSCGHYES 809

Query: 214  PKPPTSMF----------------ASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTST 257
                 S F                AS  F   G H S+   SSS+G      G       
Sbjct: 810  GSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSG------- 862

Query: 258  SHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFH--RGSTSSSPYVAASHTPP 315
                QSSSYG    H+  S   H  S    + S    S  H  RGS S            
Sbjct: 863  ----QSSSYG---QHESAS---HHASGRGRHGSGSGQSPGHGQRGSGS------------ 900

Query: 316  INGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQ 375
              G     G  G+ +G S +    G          H SSS  S+  T  GS         
Sbjct: 901  --GQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGS--------- 949

Query: 376  WPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSL 435
                 G   SS   ++   S QS   ++      +      H  G   SL  GH    S 
Sbjct: 950  -----GSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSL--GHGQHGSG 1002

Query: 436  LGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVL---------SST 486
             G S +   G   S  G SS     RS S   + R    S +G+ S L         SS 
Sbjct: 1003 SGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 1062

Query: 487  VTTSSTDLNHKTQENYRGGLQSQSGT 512
                 +   H +     G    QS +
Sbjct: 1063 YGQHGSSSGHSSTHGQHGSTSGQSSS 1088



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 89/385 (23%), Positives = 127/385 (32%), Gaps = 56/385 (14%)

Query: 48  GSGIDERGGTTSWGT-SGQPSPSYDSSRGFTDSPHYSDH-------LNDSRLGAHEGLSP 99
           GSG     G    G+ SGQ S           S  Y  H       L  SR G+  G SP
Sbjct: 482 GSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSP 541

Query: 100 TPFMNSNLMG---------------KTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPA 144
           +P    +  G               ++S RG +   S  +   G Q S   Q  G G   
Sbjct: 542 SPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHG 601

Query: 145 QLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDF 204
             SSSG   T +    +TS +        A     +   +       SS Y    +    
Sbjct: 602 --SSSGHSST-HGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQ 658

Query: 205 NRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGM------SQPGFGGILGTSTS 258
           +     + S    +S +        G H S   WSSSNG          GFG   G+  S
Sbjct: 659 SPSRGRHGSDFGHSSSY--------GQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710

Query: 259 HMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPING 318
             S  S +G+  SH    Y  H       + S     S   GS+S    +++S+    +G
Sbjct: 711 --SGYSQHGSGSSHSS-GYRKHG------SRSGQSSRSEQHGSSSG---LSSSYGQHGSG 758

Query: 319 SDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVG----SPSPLTGTS 374
           S    G     +GS  +   +    +S +S  H      ++ S+  G         +G  
Sbjct: 759 SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFG 818

Query: 375 QWPRPGGQAPSSPSYENSLHSLQSR 399
           Q     GQ  S     +   S Q R
Sbjct: 819 QHESGSGQGYSQHGSASGHFSSQGR 843



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 128/542 (23%), Positives = 180/542 (33%), Gaps = 101/542 (18%)

Query: 42   GSSQFSGSGIDERG-----GTTSWGTSGQPSPSYD--------SSRGFT------DSPHY 82
            GS Q SG G  E       G T  G+    S SY+        SSRG         S  Y
Sbjct: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSY 1923

Query: 83   SDHLNDSRL-------GAHEGLSPTPFMNSNLMGK---------------TSERGSFSLY 120
              H + SR        G+  G SP+P    +  G                +S RG +   
Sbjct: 1924 GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESG 1983

Query: 121  SRDTGLPGCQSSLLRQDLGLG----SPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALD 176
            S  +   G + S   Q  G G    S    S+ G+ G+A    S+          S++  
Sbjct: 1984 SGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHG 2043

Query: 177  PLQAKKVRKVPPGLPSSVYAPSPNSDDF---NRESPSYPSPKPPTSMFASTFFMQDGTHN 233
               +   +    G   S    SP        +R+SPSY                  G H 
Sbjct: 2044 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY------------------GRHG 2085

Query: 234  SSDLWSSSNGMSQPGFG--GILGTSTSHMSQSSSY-----GNLHSHDRLSYPPHS--VSP 284
            S    SSS+G   PG G     G   S   QSSSY     G+ HS     +   S   S 
Sbjct: 2086 SGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2145

Query: 285  TDINTSLPPMSSFH----RGSTSSSPY----VAASHTPPI------NGSDSILGTRGNAA 330
             + + S    SS +     GS  SS +      + H+P        +G  S  G  G+ +
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS 2205

Query: 331  G-SSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPS-PLTGTSQWPRPGGQAPSSPS 388
            G SS  G    ++  S     H S S  S+  +  GS S       Q     GQ+ +   
Sbjct: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265

Query: 389  YENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLN 448
              +S     S  +        + +  +    G S S     S      G  H++  G   
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGS------GSGHSSSYGQHG 2319

Query: 449  SNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQS 508
            S  G SS  +S R  S  G+ +      + + S  SS  T   +   H +     G    
Sbjct: 2320 SGSGWSS--SSGRHGS--GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG 2375

Query: 509  QS 510
            QS
Sbjct: 2376 QS 2377


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 72/299 (24%), Positives = 113/299 (37%), Gaps = 40/299 (13%)

Query: 231  THNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPH-----SVSPT 285
            T   S   SSSN    P       TST       S G   +   ++ PP       +   
Sbjct: 1017 TEGKSPSHSSSNRPFTPP------TSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKG 1070

Query: 286  DINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALAS 345
             +    P   S +  S S S   + SH    + S S   T G    S   G +  K  +S
Sbjct: 1071 TVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSS 1130

Query: 346  IYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLD 405
            +YS   +S S  S  S+               + GG+  SSP  ++ L S  S  + +  
Sbjct: 1131 MYSSQGSSGSSQSKNSS---------------QSGGKPGSSPITKHGLSSGSSSTKMKPQ 1175

Query: 406  RLDDAI--HVLRNHAVGPSTSLPAGHSD-IHSLLGPSHNAPIGS-----LNSNYGGSSLV 457
                ++    L    + PS S P G SD + S + P    P  S     ++S  GGS + 
Sbjct: 1176 GKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMS 1235

Query: 458  ASSRSASM---VGTHREDSVSLN---GNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQS 510
             +S S+ M    G     S+S      ++S  +S+ + SS+  +  + +N  G  + +S
Sbjct: 1236 GTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKS 1294


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 71/297 (23%), Positives = 114/297 (38%), Gaps = 47/297 (15%)

Query: 142 SPAQLSSSGKPGTAYYSFSA-TSSRRRPLHDSAALDPLQAKKVRKVPPG------LPSSV 194
           +P Q    G   T+  S +A  +S   P+       P +++K    PPG       PSS 
Sbjct: 434 APKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSS 493

Query: 195 YAPSPNSDDFNRESPSYPSPKPPTSM-FASTFFMQDGTHNSSDLWS-------------- 239
             P+  S       P + S  PP S+   + FF Q  T  ++   +              
Sbjct: 494 SLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAV 553

Query: 240 --------SSNGMSQPGFG-GILGTSTSHMSQSSSYGNLHSHDRLSYPPHS--VSPTDIN 288
                   S++  S+P FG GI   S+S +S ++S     S   L   P +   S T   
Sbjct: 554 APITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAASFTPAM 613

Query: 289 TSL-----PP-------MSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTG 336
            S+     PP       +++F +   ++ P   +S     +G  S L T   A  S  T 
Sbjct: 614 GSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSAPATSSQPTL 673

Query: 337 DALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPS-SPSYENS 392
                +  +   P  +S+  P  PS P  +P P  G ++   PG   P+ +PS+ +S
Sbjct: 674 TFSNTSTPTFNIPFGSSAKSPL-PSYPGANPQPAFGAAEGQPPGAAKPALAPSFGSS 729


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 83/323 (25%), Positives = 114/323 (35%), Gaps = 54/323 (16%)

Query: 147 SSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNR 206
           SS+    T   S S T  R+RP    A++  ++   V+K   G+    +         NR
Sbjct: 461 SSNHSFHTGNDSDSGTLERKRP----ASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNR 516

Query: 207 E--SPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSS 264
           +  SP++  P PPT          +    SS   SSS G + P   GIL        Q  
Sbjct: 517 KHISPAFQPPLPPTDGSTVVPAGPEPPPQSSRAESSSGGGTVPSSAGIL-------EQGP 569

Query: 265 SYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSI-L 323
           S G+         PP    P       P  ++    S  + P  AA       GS  + +
Sbjct: 570 SPGD-------GSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAA-------GSHQLSM 615

Query: 324 GTRGNAAGSSQ--TGDALGKALASIYSPDH-------------TSSSFPS-NPSTPVGSP 367
           G   NAAG S      A+ K   +   P +             TS   PS +P  P  SP
Sbjct: 616 GQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSP 675

Query: 368 SPLTGTSQWPRPGGQAPSSPS-------YENSLHSLQSRMEDRLDRLDDAIHVLRNHAVG 420
           SP   T    +P GQ PS+PS       Y +SL  +Q+           A  ++      
Sbjct: 676 SP--PTQHTGQPPGQ-PSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNS 732

Query: 421 PSTSLPAGHSDIHSLLGPSHNAP 443
                P      H L  PSH  P
Sbjct: 733 QGPPNPMALPSEHGLEQPSHTPP 755



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 58/226 (25%), Positives = 82/226 (36%), Gaps = 55/226 (24%)

Query: 177 PLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSD 236
           P  A    ++  G P +   PSP++    R +   P+P PP                   
Sbjct: 604 PQAAAGSHQLSMGQPHNAAGPSPHT---LRRAVKKPAPAPPKP----------------- 643

Query: 237 LWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPP-HSVSPTDINTSLPP-- 293
                 G   PG  G          QSSS  + H       PP  S SP   +T  PP  
Sbjct: 644 ------GNPPPGHPG---------GQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQ 688

Query: 294 ------MSSFHRGSTSSSPYVAASHTPPINGSDS--ILGTRGNAAGSSQTGDALGKALAS 345
                 +S+  R S+S SP  A +H PP   + +  ++ T+ N+ G          AL S
Sbjct: 689 PSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNP-----MALPS 743

Query: 346 ---IYSPDHTSSSFPSNPST-PVGSPSPLTGTSQWPRPGGQAPSSP 387
              +  P HT    P+ PST P+G  +P     Q    G    + P
Sbjct: 744 EHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQP 789


>gi|118498337 HECT domain containing 1 [Homo sapiens]
          Length = 2610

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 84/385 (21%), Positives = 138/385 (35%), Gaps = 78/385 (20%)

Query: 213  SPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSH 272
            SPKP +S  + T          +  WSS    + P        S+S    SSS  ++ S 
Sbjct: 1345 SPKPVSSTVSGT----------TQSWSSLVKNNCPDKTSAAAGSSSRKGSSSSVCSVASS 1394

Query: 273  DRLSYPP------------HS-VSPTDINTSLPPMSSFHR-------GSTSSSPYVAASH 312
              +S               HS VS  D++  +  +SS           S+S+S     + 
Sbjct: 1395 SDISLGSTKTERRSEIVMEHSIVSGADVHEPIVVLSSAENVPQTEVGSSSSASTSTLTAE 1454

Query: 313  TPPIN-----GSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSP 367
            T   N     G DS + T G ++       A+   + S+ SPD +S S  +N       P
Sbjct: 1455 TGSENAERKLGPDSSVRTPGESS-------AISMGIVSVSSPDVSSVSELTNKEAASQRP 1507

Query: 368  -----SPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRL--------------- 407
                 S     S     G    SS S  N      S +E  + R+               
Sbjct: 1508 LSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNATNNMNLS 1567

Query: 408  ----DDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSA 463
                D+  + L  + +  +TS   G     +L  P   + +    S+   SS VA++ + 
Sbjct: 1568 RSSSDNNTNTLGRNVMSTATSPLMGAQSFPNLTTPGTTSTVTMSTSSVTSSSNVATATTV 1627

Query: 464  SMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENK 523
              VG    ++++        S T T+S +D   + + +    L S   + +  E+     
Sbjct: 1628 LSVGQSLSNTLTT-------SLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAEL----- 1675

Query: 524  EKDENLHEPPSSDDMKSDDESSQKD 548
            + DE+L EP   DD   DD    ++
Sbjct: 1676 DDDEDLPEPDEEDDENEDDNQEDQE 1700


>gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo
           sapiens]
          Length = 514

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 67/267 (25%), Positives = 105/267 (39%), Gaps = 37/267 (13%)

Query: 254 GTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINT-SLPPMSSFHRGSTSSSPYVAASH 312
           GT +   S   +  +L + +  + P  ++  T+I + S P  SS    ST S+P    S 
Sbjct: 155 GTLSMETSLPPTSSSLPTTETATTPTTNLVTTEITSHSTPSFSSSTIHSTVSTPTTVISS 214

Query: 313 TPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTG 372
            PP +G+   + T      SS + D     L +  +  H S     +  T     S  T 
Sbjct: 215 GPPTSGT---IVTSITVTPSSLSTDI---PLTTPTTITHHSVGSTESLLTATDLTSTFTV 268

Query: 373 TSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDI 432
           +S         PSSPS +N+  S    M                     S ++P+    +
Sbjct: 269 SSSSAMSTSDIPSSPSIQNTETSSLVSMT--------------------SATIPS----V 304

Query: 433 HSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVG-THREDSVSLNGNHSVLSSTVTTSS 491
                 +HN    SL + + G+   +SS SAS  G TH E   SL  + S L    TT+ 
Sbjct: 305 RPTFTSTHNTLTSSLLTTFPGTYSFSSSMSASSDGTTHTETITSLPASTSTLH---TTAE 361

Query: 492 TDLNHKTQENYRGG--LQSQSGTVVTT 516
           +   H T  ++     ++S S +V TT
Sbjct: 362 STTAHTTTTSFTTSTTMESPSSSVATT 388


>gi|47716512 mex-3 homolog B [Homo sapiens]
          Length = 569

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 72/277 (25%), Positives = 107/277 (38%), Gaps = 37/277 (13%)

Query: 250 GGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPT-----------DINTSLPPMS--S 296
           G  +G    H S  S  G+L S      P  S++PT           D ++SL   S  S
Sbjct: 245 GTDVGFDLHHGSGGSGPGSLWSK-----PTPSITPTPGRKPFSSYRNDSSSSLGSASTDS 299

Query: 297 FHRGSTSSSPYVA---ASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPD--- 350
           +  G TSSS       A ++PP            N  G+  T  A G+A  S+ SPD   
Sbjct: 300 YFGGGTSSSAAATQRLADYSPPSPALSFAHNGNNNNNGNGYTYTAGGEA--SVPSPDGCP 357

Query: 351 HTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRME------DRL 404
               +F   P+ P G+P       + P  G  AP S S  +S  S  S            
Sbjct: 358 ELQPTFDPAPAPPPGAPLIWAQFERSPGGGPAAPVSSSCSSSASSSASSSSVVFPGGGAS 417

Query: 405 DRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLV----ASS 460
              +  + +L +  + P TS P     +H   G   +     + S+ GG  L     A+ 
Sbjct: 418 APSNANLGLLVHRRLHPGTSCPRLSPPLHMAPGAGEHHLARRVRSDPGGGGLAYAAYANG 477

Query: 461 RSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHK 497
             A + G    D+ S + + S  SS+ ++SS+ L  K
Sbjct: 478 LGAQLPGLQPSDT-SGSSSSSSSSSSSSSSSSGLRRK 513


>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1230

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 100/388 (25%), Positives = 146/388 (37%), Gaps = 50/388 (12%)

Query: 28  SPPVNSGKTRPTTLGSS----------QFSGSGIDERGGTTSWGTSGQPSPS----YDSS 73
           S P NSG   P+  G+S            SG+      G  S+  S    PS       S
Sbjct: 29  STPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPSDSGWASPS 88

Query: 74  RGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSL 133
             +  +P  S   + S  GA    S + + + ++ G        S+ S     P    + 
Sbjct: 89  ASWASTPSDSGWASPSASGASIP-SDSGWASPSVSGA-------SIPSAFWASPSASGAS 140

Query: 134 LRQDLGLGSPAQ--LSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGL- 190
              D G  SP+    S+S   G A  S S TS        SA+     +      P    
Sbjct: 141 TPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASPSVFW 200

Query: 191 --PSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPG 248
             PS+ +A SP+  DF   S       P  S +AS+         S    SS +G + P 
Sbjct: 201 VSPSTSWASSPS--DFGWAS------TPSDSGWASSSASCISPSASGASTSSDSGWASPS 252

Query: 249 FGGILGTSTSHMSQSSSYG---NLHSHDRLSYPPHSVSPT-DINTSLPPMSSFHRGSTSS 304
              +  TSTS  S SS  G   +  S D ++     V P+    +S    +S    S SS
Sbjct: 253 ASWV-STSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSS 311

Query: 305 SPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPV 364
           SP V+ + T  ++G  S      +A+G+S   D+ G    S      TS S  ++PS   
Sbjct: 312 SPSVSRASTLSVSGWASF-----SASGASAPSDS-GWTSHSASGVSTTSDSGWASPSASG 365

Query: 365 GSPSPLTG----TSQWPRPGGQAPSSPS 388
            S S  +G    ++ W  P     S+PS
Sbjct: 366 ASTSSDSGWASPSASWASPSASGASTPS 393



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 92/393 (23%), Positives = 143/393 (36%), Gaps = 57/393 (14%)

Query: 28  SPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGT----SGQPSPSYDSSRGFTDSPHYS 83
           S P +SG   P+  G+S  S SG      + SW +    SG  SPS   +   +DS   S
Sbjct: 45  SIPSDSGWASPSASGASTPSNSGW--ASFSASWASIPSDSGWASPSASWASTPSDSGWAS 102

Query: 84  DHLNDSRLGAHEGLSPTPFMNSNLMGK--TSERGSFSLYSRDTGL--PGCQSSLLRQDLG 139
              + + + +  G +      +++      S   S +    D+G   P    +    D G
Sbjct: 103 PSASGASIPSDSGWASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSG 162

Query: 140 LGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGL-----PSSV 194
             SP+   +S     A  S S  S+      DS    P     V  V P       PS  
Sbjct: 163 WASPSASWTSPSASCASSSASGASTPS----DSGWASP----SVFWVSPSTSWASSPSDF 214

Query: 195 -YAPSPNSDDFNRESPSYPSPKP-------------PTSMFASTFFMQDGTHNSSDLWSS 240
            +A +P+   +   S S  SP               P++ + ST   +  T + S  W+S
Sbjct: 215 GWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSG-WAS 273

Query: 241 SNGM--SQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFH 298
           S+    S     G +  S S  S S+S+ +  S    S P  S + T   +     S+  
Sbjct: 274 SSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASG 333

Query: 299 RGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPS 358
             + S S + + S +     SDS   +   +  S+ +        AS  SP  + +S PS
Sbjct: 334 ASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPS 393

Query: 359 NPSTPVGSPSPLTGTSQWPRP---GGQAPSSPS 388
           +              S W  P   G   PS+PS
Sbjct: 394 D--------------SGWASPSASGASMPSAPS 412



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 87/348 (25%), Positives = 123/348 (35%), Gaps = 27/348 (7%)

Query: 127 PGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKV 186
           P    + +  D G  SP+   +S    + + SFSA  S      DS    P  +      
Sbjct: 39  PSASGASIPSDSGWASPSASGASTPSNSGWASFSA--SWASIPSDSGWASPSASWASTPS 96

Query: 187 PPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFAS------TFFMQDGTHNSSDLW-- 238
             G  S   + +    D    SPS      P++ +AS      +     G  + S  W  
Sbjct: 97  DSGWASPSASGASIPSDSGWASPSVSGASIPSAFWASPSASGASTPSDSGWASPSASWAS 156

Query: 239 -SSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPP-HSVSPTDINTSLPPMSS 296
            SS +G + P        S S  S S+S  +  S    + P    VSP+    S P  S 
Sbjct: 157 TSSDSGWASPS-ASWTSPSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSP--SD 213

Query: 297 FHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSF 356
           F   ST S    A+S    I+ S S       A+ SS +G A   A     S    S+S 
Sbjct: 214 FGWASTPSDSGWASSSASCISPSAS------GASTSSDSGWASPSASWVSTSTSRASTSS 267

Query: 357 PSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRN 416
            S  ++   S   +T  S W  P      S S+ +S  S  S   D              
Sbjct: 268 DSGWASSSASWDSITSDSGWVCP------SASWASSSASWASAPSDSGSSSPSVSRASTL 321

Query: 417 HAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSAS 464
              G ++   +G S        SH+A   S  S+ G +S  AS  S S
Sbjct: 322 SVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTS 369


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 83/393 (21%), Positives = 148/393 (37%), Gaps = 45/393 (11%)

Query: 190  LPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGF 249
            + ++V  P+P++      S    + K   + F +    +  T   S   + ++ +     
Sbjct: 5156 ITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVP 5215

Query: 250  GGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVS---PTDINTSLPPMSSFHRGSTSSSP 306
             G +   +S    SSS  +   HD+ + PP + +   P    +S+   S+    +T +SP
Sbjct: 5216 TGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTITTQASP 5275

Query: 307  YVAASH-TPPINGSDSIL--GTRGNAAGS---SQTGDALGKALASIY----SPDHTSSSF 356
              +ASH T P++ S ++   GT          S+    +G    ++      P   +SS 
Sbjct: 5276 PESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGNVSWMTTPPVEETSSV 5335

Query: 357  PSNPSTP-VGSPSPLTGTSQWPRPGGQAP--------------------------SSPSY 389
             S  S+P + SPSP++ TS    P    P                          S P+ 
Sbjct: 5336 SSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPNL 5395

Query: 390  ENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNA---PIGS 446
             +  H   +  +D     + A+H   N AV    +  +GH    S+L  S  +   P+ S
Sbjct: 5396 SSITHERPATYKDTA-HTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMS 5454

Query: 447  LNSNYGGSSLVASSRSASMVG-THREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGG 505
              S  G +S+  S+ + S       E + SL+      S++  TSST   +        G
Sbjct: 5455 TTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTG 5514

Query: 506  LQSQSGTVVTTEIKTENKEKDENLHEPPSSDDM 538
              +Q+     +  +T   + D     P  S  M
Sbjct: 5515 AITQASRTEISSSRTSISDLDRPTIAPDISTGM 5547



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 98/425 (23%), Positives = 147/425 (34%), Gaps = 89/425 (20%)

Query: 187  PPGLPSS---VYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNG 243
            PP  P S   V +P P S  F    P  PSP P TS+  S      G   ++D       
Sbjct: 7686 PPSSPLSLPAVTSPHPVSTTFLAHIP--PSPLPVTSLLTS------GPATTTD------- 7730

Query: 244  MSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLS-----------YPPHSVSPTDINTSLP 292
                    ILGTST   + SSS  +  SH+RL+           +P  +   T++ T+  
Sbjct: 7731 --------ILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSS 7782

Query: 293  PMSSFHRGSTSSSPYVAAS---HTPPINGSDSILGTR------------GNAAGSSQTGD 337
               S       SSP    S    T  +  + + L TR            G    S   G 
Sbjct: 7783 GYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGT 7842

Query: 338  ALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQ---WPRPGGQAPSSPSYENSLH 394
            + G  ++++ S   T ++   +       P P   T       R      +SP    S  
Sbjct: 7843 SSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAE 7902

Query: 395  SLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPI---GSLNSNY 451
               +     L         L   +   +TSL   HS I      S  + +   G  + ++
Sbjct: 7903 ITMNTHTSPLGATTQGTSTLDTSS---TTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSW 7959

Query: 452  GGSSLVASSRSA----SMVGTHREDSVSLNGNHSVLSSTVTTSS---------TDLNHKT 498
                L+  +R +    S   T     VS     S+ SS +  +S         TD+ HK+
Sbjct: 7960 MSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKS 8019

Query: 499  QE---NYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRG 555
             E   N    L S S  ++ T   T + EK       PSS+        +  D+  SS G
Sbjct: 8020 SEPVTNSPANLSSTSVEILATSEVTTDTEKTH-----PSSN-------RTVTDVGTSSSG 8067

Query: 556  RTSST 560
              S++
Sbjct: 8068 HESTS 8072



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 97/392 (24%), Positives = 145/392 (36%), Gaps = 88/392 (22%)

Query: 209  PSYPSPKPPTSMFASTFFMQDGTHNSSDLWSS--SNGMSQPGFG---GILGTSTSHM--- 260
            P+Y  P   TS   ++F ++D   ++S   SS  +    +  F    G+ GTSTS     
Sbjct: 6611 PAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIV 6670

Query: 261  --------------SQSSSYGNLHSHDRLSYP--PHSVSPTDINTSLPPMSSFHRGSTSS 304
                          +  +S   + S  R S P   HS    DI+T + P      G T S
Sbjct: 6671 STEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITES 6730

Query: 305  SPYVAASHTPPINGSDS------ILGTRGNAAGS----------SQTGDALGK---ALAS 345
            S     + T P  GS S         T  + AG+          S+    + K    L+ 
Sbjct: 6731 SNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSW 6790

Query: 346  IYSPDHTSSSF-------PSNPSTPVGS---------PSPLT--------------GTSQ 375
               P    +SF       P+  S PV S         PSP+T              GTS 
Sbjct: 6791 TIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTS- 6849

Query: 376  WPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSL 435
             P P   +P  P+  ++ H + +  ED      +A+H   + A     +  +GH    S+
Sbjct: 6850 -PEPTTSSP--PNLSSTSHEILTTDED--TTAIEAMHPSTSTAATNVETTSSGHGSQSSV 6904

Query: 436  LGPSH----NAPIGSLNSNYGGSSLVASSRSASMVGT--HREDSVSLN-GNHSVLSSTVT 488
            L  S      AP+ + ++   G + V++S S S   T   RE + SL  G      S   
Sbjct: 6905 LADSEKTKATAPMDTTSTM--GHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNA 6962

Query: 489  TSSTDLNHKTQENYRGGLQSQSGTVVTTEIKT 520
            + STD +    E   G     S T VT+  +T
Sbjct: 6963 SFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRT 6994



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 59/239 (24%), Positives = 105/239 (43%), Gaps = 23/239 (9%)

Query: 252  ILGTSTSHMSQSSSYGNLHSHDRLSYPPHS---VSPTDINTSLPPMSSFHRGSTSSSPYV 308
            I+ TST  + QS+   +  S +++S    S   V+   ++ S    +S   GS++SSPY 
Sbjct: 1972 IVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYS 2031

Query: 309  AASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPS 368
            +AS    +   DS +  R   A +S   D L  +L +   P  + S   S+  + V +PS
Sbjct: 2032 SAS----LESLDSTISRRN--AITSWLWD-LTTSLPTTTWPSTSLSEALSSGHSGVSNPS 2084

Query: 369  PLTGTSQWPRPGGQAPSSPSYEN---SLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSL 425
              + T+++P     + S+    N     H  Q+     L+    ++  L    VG S S 
Sbjct: 2085 --STTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASIS- 2141

Query: 426  PAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLS 484
                S++   +  +  + +  L S    S+   S  +AS  GT    ++SL  + S++S
Sbjct: 2142 ----SEVPLPMAITSRSDVSGLTSE---STANPSLGTASSAGTKLTRTISLPTSESLVS 2193



 Score = 33.1 bits (74), Expect = 0.87
 Identities = 67/320 (20%), Positives = 124/320 (38%), Gaps = 37/320 (11%)

Query: 208  SPSYPSPKPPT--------SMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSH 259
            S S P+P  PT        + F+S+  + +    SS   ++S G + P    + GT+T  
Sbjct: 890  STSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMS 949

Query: 260  MSQSSSYGNLHSHDRLSYPPHS--------VSPTDINTSLPPMSSFHRGSTSSSPYVAAS 311
             +   ++ +  +    ++P  S         + T ++TS   +S+    S  +SP  ++ 
Sbjct: 950  QTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSM 1009

Query: 312  HTPPI-NGSDSILGTR-GNAAGS---SQTGDALGKA------LASIYSPDHTSSSFPSNP 360
                I   S +IL T   N  GS   + T   +GK       L + + P  T++S  ++ 
Sbjct: 1010 EATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSM 1069

Query: 361  STPVG--------SPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSR-MEDRLDRLDDAI 411
               +         SPS     +    PG  +    ++ + ++ L SR +    D    A+
Sbjct: 1070 DFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSAL 1129

Query: 412  HVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLN-SNYGGSSLVASSRSASMVGTHR 470
                     PS    +  S    +L  S ++P   +  S+   +  V +S     V T R
Sbjct: 1130 TPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSR 1189

Query: 471  EDSVSLNGNHSVLSSTVTTS 490
             +  +L    S+  S + TS
Sbjct: 1190 WNMPNLPSTTSLTPSNIPTS 1209



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 105/529 (19%), Positives = 183/529 (34%), Gaps = 70/529 (13%)

Query: 61   GTSGQPSPSYDSSRGFTDS---PHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSF 117
            G S Q  PS + +   +     P  + H   S   A  G SPT  +    +  +  R + 
Sbjct: 5912 GVSWQSPPSVEETSSPSSPVPLPAITSH--SSLYSAVSGSSPTSALPVTSLLTSGRRKTI 5969

Query: 118  SLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSA------TSSRRRPLHD 171
             +   DT      SSL       G      +S    T ++S +       T++    LH 
Sbjct: 5970 DML--DTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSENTAETNMGTTNSMHKLHS 6027

Query: 172  SAALDPLQAKKVRKVPPGLPSS------VYAPSPNSDDFNRESPSYPSPKPPTSMFASTF 225
            S ++    ++     PP +  S      V   +P S +         SP  P     ST 
Sbjct: 6028 SVSI---HSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTA 6084

Query: 226  FMQDGTHNSSDLWSSSN------------GMSQPGFGGILGTSTSHMSQSSSYGNLHSHD 273
             + + T  S+ ++SS +                P F      ST     S    + HS+ 
Sbjct: 6085 LVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNS 6144

Query: 274  RLSYPPHSVSP-TDINTSLPPMSSFHRGS-TSSSPYVAASHTPPINGSDSILGTRGNAAG 331
                PP ++S    I T   P      G  T  +  +A S   P   +   + +   +  
Sbjct: 6145 ----PPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVM 6200

Query: 332  SSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYEN 391
            ++   D L     S +S +  +S     P     SPSP+T T Q         S  S   
Sbjct: 6201 NNDLNDVLK---TSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQ-EHSTSSLVSVTSVPT 6256

Query: 392  SLHSLQSRMEDRLDRLDDAIHVLRN-----------HAVGPSTSLPAGH-------SDIH 433
               +  + M+  L+ +  +   LRN           H + PS +    +       ++ +
Sbjct: 6257 PTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFY 6316

Query: 434  SLLGPS---HNAPIGSLNSNYGGSSLVASS--RSASMVGTHREDSVSLNGNHSVLSSTVT 488
              + P    + A    + ++  G S+V++S  RS++M     E + SL      L  T T
Sbjct: 6317 FTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFR---LRETST 6373

Query: 489  TSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDD 537
            +     +  T   +     + +  V  TE+ + ++   +   +P  S D
Sbjct: 6374 SQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPD 6422



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 77/334 (23%), Positives = 125/334 (37%), Gaps = 26/334 (7%)

Query: 147  SSSGKPGTAYYSFSATSSR--RRPLHDSAALDPLQAKKVR-KVPPGLPSSVYAPSPNSDD 203
            + S  P  ++ + +AT S+  R   +DSAA       +   +   GLPS+    S ++  
Sbjct: 932  TGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATS 991

Query: 204  FNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQS 263
             +          P TS   +T   +  T   +    ++NG   PG   +  T+       
Sbjct: 992  LSATVMVSKFTSPATSSMEATSIREPSTTILTT--ETTNG---PGSMAVASTNIPIGKGY 1046

Query: 264  SSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSIL 323
             + G L +   L     + S T ++ ++   S     S S S   A S TP         
Sbjct: 1047 ITEGRLDT-SHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPG-------- 1097

Query: 324  GTRGNAAGSSQTGDALGKALASIYSP-DHTSSSF-PSNPSTPVGSPSPLTGTSQWPRPGG 381
              R +    + + D        I  P D TSS+  P   +T   SP P +  S W     
Sbjct: 1098 --RTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILS 1155

Query: 382  QAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLR-NHAVGPS-TSLPAGHSDIHSLLGPS 439
             +PSSP+ + ++ S  S        + D +   R N    PS TSL   +      +G S
Sbjct: 1156 SSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKS 1215

Query: 440  HNAPIGSLNSNYGGSSLVASSRSASMVGTHREDS 473
               P   L++    +SL AS      + T+ E +
Sbjct: 1216 TLVP---LDTPSPATSLEASEGGLPTLSTYPEST 1246



 Score = 29.6 bits (65), Expect = 9.6
 Identities = 47/209 (22%), Positives = 70/209 (33%), Gaps = 32/209 (15%)

Query: 207  ESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSY 266
            ES SYP P   +S   ST      T   S   ++ +G S           TS +S ++S 
Sbjct: 2990 ESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTAST 3049

Query: 267  GNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTR 326
                S   L   P      +I   L   +S    S +S+  ++    P +  S +I    
Sbjct: 3050 SRKTS---LFLGPSMARQPNILVHL--QTSALTLSPTSTLNMSQEEPPELTSSQTIAEEE 3104

Query: 327  GNAAGSSQ---TGDALGKALASIYSPDHTSSSFPSNPSTPVGSPS--------------- 368
            G  A +     T      +L  + SP   ++   S+P T   S S               
Sbjct: 3105 GTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTL 3164

Query: 369  ---------PLTGTSQWPRPGGQAPSSPS 388
                        G S WP P  +  SSP+
Sbjct: 3165 VTTIKMSSQAAQGNSTWPAPAEETGSSPA 3193


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 98/403 (24%), Positives = 151/403 (37%), Gaps = 80/403 (19%)

Query: 32  NSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL 91
           +S ++  TTL  +  + SG+ E   T+        + ++  S   T +P  S H   S  
Sbjct: 130 SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS---TTTPGLSRHSTTSH- 185

Query: 92  GAHEGLSPTPFMNSNLMGKTSERGSFSLYSR----DTGL-PGCQSSLLRQDLGLGSPAQL 146
            +  G + T  + ++       + S + +S     DT L PG  ++L     G  S    
Sbjct: 186 -SSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTAL---SFGQESTTFH 241

Query: 147 SSSGKPGTAYYSFSATSS----RRRPLHDSAALDPLQAKKVRKVPPGL------------ 190
           SS G   T  +  S TSS        +H S               PGL            
Sbjct: 242 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 301

Query: 191 --------PSSVYAPSPNSDDFNRESPSYPSPKPPTSMFA------STFFMQ----DGTH 232
                   PS+  AP   S  ++R   S P+   P S         ST F       GT 
Sbjct: 302 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 361

Query: 233 NSSD-------LWSSSNGMSQPG------FGGILGTS-------TSHMSQSSSYGNLHSH 272
            SS           SS   SQPG      F     TS       TSH SQ S+   L + 
Sbjct: 362 PSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTT 421

Query: 273 DRLSYPPHSVSPTDINTSLPPMSSFH-RGSTSSSPYVAASHTPPINGSDSILGTRGNAAG 331
              S P  + +P +++T      ++H R S++ + + +AS T      +S   T  ++ G
Sbjct: 422 P--SPPGTTAAPVEVST------TYHSRPSSTPTTHFSASSTTLGRSEEST--TVHSSPG 471

Query: 332 SSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTS 374
           S++T    G    +  S    S++F S+P +P  + SP + TS
Sbjct: 472 STETTALPGSTTTAGLS--EKSTTFYSSPRSPDTTLSPASTTS 512



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 58/285 (20%), Positives = 104/285 (36%), Gaps = 30/285 (10%)

Query: 299 RGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPS 358
           RG  S++ + + +HT     S +        +  S  G       A+ + PD +++S  S
Sbjct: 12  RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST-----ATTHFPDSSTTSGRS 66

Query: 359 NPSTPVGSPSPLTGTSQWPRPG------GQAPSSPSYENSLHSLQSRMEDRLDRLDDAIH 412
             ST   S    TGT   P         G++ +SP    S+ +           L +   
Sbjct: 67  EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST 126

Query: 413 VLRNHAVGPSTSL-PAG--HSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTH 469
              +    P+T+L PA    S +      SH+ P        G +   A   S +  G  
Sbjct: 127 TFHSSPRSPATTLSPASTTSSGVSEESTTSHSRP--------GSTHTTAFPDSTTTPGLS 178

Query: 470 REDSVSLNG----NHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEK 525
           R  + S +     + ++L ++ TTS       T  +  G   +      TT +     ++
Sbjct: 179 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF--GQE 236

Query: 526 DENLHEPPSS--DDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNP 568
               H  P S    +  D  +S   ++ S+R  +S+ +    L+P
Sbjct: 237 STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSP 281


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 98/403 (24%), Positives = 151/403 (37%), Gaps = 80/403 (19%)

Query: 32  NSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRL 91
           +S ++  TTL  +  + SG+ E   T+        + ++  S   T +P  S H   S  
Sbjct: 24  SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS---TTTPGLSRHSTTSH- 79

Query: 92  GAHEGLSPTPFMNSNLMGKTSERGSFSLYSR----DTGL-PGCQSSLLRQDLGLGSPAQL 146
            +  G + T  + ++       + S + +S     DT L PG  ++L     G  S    
Sbjct: 80  -SSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTAL---SFGQESTTFH 135

Query: 147 SSSGKPGTAYYSFSATSS----RRRPLHDSAALDPLQAKKVRKVPPGL------------ 190
           SS G   T  +  S TSS        +H S               PGL            
Sbjct: 136 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 195

Query: 191 --------PSSVYAPSPNSDDFNRESPSYPSPKPPTSMFA------STFFMQ----DGTH 232
                   PS+  AP   S  ++R   S P+   P S         ST F       GT 
Sbjct: 196 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 255

Query: 233 NSSD-------LWSSSNGMSQPG------FGGILGTS-------TSHMSQSSSYGNLHSH 272
            SS           SS   SQPG      F     TS       TSH SQ S+   L + 
Sbjct: 256 PSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTT 315

Query: 273 DRLSYPPHSVSPTDINTSLPPMSSFH-RGSTSSSPYVAASHTPPINGSDSILGTRGNAAG 331
              S P  + +P +++T      ++H R S++ + + +AS T      +S   T  ++ G
Sbjct: 316 P--SPPGTTAAPVEVST------TYHSRPSSTPTTHFSASSTTLGRSEEST--TVHSSPG 365

Query: 332 SSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTS 374
           S++T    G    +  S    S++F S+P +P  + SP + TS
Sbjct: 366 STETTALPGSTTTAGLS--EKSTTFYSSPRSPDTTLSPASTTS 406


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 119/556 (21%), Positives = 182/556 (32%), Gaps = 76/556 (13%)

Query: 36   TRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSR--GFTDSPHYSDHLNDSRLGA 93
            +R + +G  Q SG       G++    S     S DS R  G     H       SR G+
Sbjct: 1895 SRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGS 1954

Query: 94   -HEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKP 152
             H G               +  G  +  SR +G    +SS   Q       A+ S+  + 
Sbjct: 1955 RHPGSHHED---------RAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERH 2005

Query: 153  GTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFN-----RE 207
            G+ +   SA SSR   +    A   ++    R       S     S +SD  +     + 
Sbjct: 2006 GSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKA 2065

Query: 208  SPSYPSPKPP-------TSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGT----- 255
             P   S K         +S  + +F  Q  TH  S+   S++G S P  GG  G+     
Sbjct: 2066 GPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSE---STHGQSAPSTGGRQGSHYDQA 2122

Query: 256  --STSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHT 313
              S+ H +       +  H   S      S  +         S  R   S S +   SHT
Sbjct: 2123 QDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQE--------QSVDRSGHSGSHH---SHT 2171

Query: 314  PPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDH---TSSSFPSNPSTPVGSPSPL 370
                 SD+  G  G+ + S +T D       S +S  H    SS   S+  + VG     
Sbjct: 2172 TSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQ---- 2227

Query: 371  TGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPA--- 427
             G S  PR      SS S ++         E R        H          +  P    
Sbjct: 2228 -GQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHH 2286

Query: 428  ------GHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHS 481
                  GHS   S    +H+A   S       S   A S +    G+H + S   + +  
Sbjct: 2287 EDRAGHGHSAESSRQSGTHHAE-NSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSG 2345

Query: 482  VLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSD 541
            +     +++  D  H      RG   SQ+         +E   +D +     +       
Sbjct: 2346 IGHGQASSAVRDSGH------RGSSGSQAS-------DSEGHSEDSDTQSVSAHGQAGPH 2392

Query: 542  DESSQKDIKVSSRGRT 557
             +S Q+  +  S GR+
Sbjct: 2393 QQSHQESTRGRSAGRS 2408



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 124/565 (21%), Positives = 187/565 (33%), Gaps = 81/565 (14%)

Query: 36   TRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSR--GFTDSPHYSDHLNDSRLGA 93
            +R + +G  Q SGS      G++    S     S DS R  G     H+      SR G+
Sbjct: 1247 SRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGS 1306

Query: 94   -HEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKP 152
             H G               +  G  +  SR +G    +SS   Q +     A+ S   + 
Sbjct: 1307 RHPGFHQED---------RASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERH 1357

Query: 153  GTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYP 212
            G+ +   SA SSR   +              R+    +  S +  S  S   N E  S  
Sbjct: 1358 GSRHQQ-SADSSRHSGIGH------------RQASSAVRDSGHRGSSGSQVTNSEGHSED 1404

Query: 213  SPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSH 272
            S     S        Q G H  S    S+ G S    G   G S S + Q SS+    S 
Sbjct: 1405 SDTQSVSAHG-----QAGPHQQSHK-ESARGQS----GESSGRSRSFLYQVSSHEQSES- 1453

Query: 273  DRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGS 332
                           +    P +   +GS       ++ H+   +G D+I G  G++ G 
Sbjct: 1454 --------------THGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGG 1499

Query: 333  SQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENS 392
             Q          S +S  H S + P   S      S     S+  R   Q     S + S
Sbjct: 1500 RQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQ-----SGDGS 1554

Query: 393  LHSLQSRMEDRLDRLDDAIH--VLRNHAVGPSTSLPAGHSDIHSLLGPSHNAP----IGS 446
             HS  SR  +   R   + H  V +  + G  TS   G S         H+        S
Sbjct: 1555 RHS-GSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSES 1613

Query: 447  LNSNYGGSSLVASSRSASMVGTHREDSVS----------LNGNHSVLSSTVTTSSTDLNH 496
             + N+ GS+   S   +    +H+ED  S              H+  SS    +S+    
Sbjct: 1614 ASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQA 1673

Query: 497  KTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEP---PSSDDMKSDDESSQKDIKVSS 553
            ++    R G + Q     +T+  T  ++    + +     SS    SD E        S 
Sbjct: 1674 RSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGH------SE 1727

Query: 554  RGRTSSTNEDEDLNPEQKIEREKER 578
               T S +      P Q+  +E  R
Sbjct: 1728 ESDTQSVSAHGQAGPHQQSHQESTR 1752



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 127/576 (22%), Positives = 185/576 (32%), Gaps = 81/576 (14%)

Query: 36   TRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSR--GFTDSPHYSDHLNDSRLGA 93
            +R +  G  Q  GS    R G++    S     S DS R  G     H       SR G+
Sbjct: 923  SRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGS 982

Query: 94   HEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPG 153
                S             +  G  +  SR +G P  ++S   Q       A+ S   + G
Sbjct: 983  RHPRSHHE--------DRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHG 1034

Query: 154  TAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPS 213
            + +   SA SSR   +              R+    +  S +  S  S   + E  S  S
Sbjct: 1035 SRHQQ-SADSSRHSGIPR------------RQASSAVRDSGHWGSSGSQASDSEGHSEES 1081

Query: 214  PKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHD 273
                 S        QDG H  S   S+ +       GG  G S S + Q S++    S  
Sbjct: 1082 DTQSVSGHG-----QDGPHQQSHQESARDWS-----GGRSGRSGSFIYQVSTHEQSES-- 1129

Query: 274  RLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSS 333
                  H  + T          S H  +  SS + A+       G D+I    G+  G  
Sbjct: 1130 -----AHGRTRTSTGRR---QGSHHEQARDSSRHSASQE-----GQDTIRAHPGSRRGGR 1176

Query: 334  QTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSL 393
            Q          S +S  H S +     S      S     S+  R   Q     S + S 
Sbjct: 1177 QGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQ-----SGDGSR 1231

Query: 394  HSLQSRMEDRLDRLDDAIH--VLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPI----GSL 447
            HS  SR  +     D + H  V +  + G  TS   G S         H+       GS 
Sbjct: 1232 HS-GSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSA 1290

Query: 448  NSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQ 507
            + N+ GSS   S   +   G H+ED  S    HS  SS  + +     H T+ +  G   
Sbjct: 1291 SRNHHGSSREQSRDGSRHPGFHQEDRAS--HGHSADSSRQSGT-----HHTESSSHGQAV 1343

Query: 508  SQSGTVVTTEIKTENKEKDENL---------HEPPSSDDMKSDDESSQKDIKVSSRGR-- 556
            S      ++  +       ++          H   SS    S    S      +S G   
Sbjct: 1344 SSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSE 1403

Query: 557  ---TSSTNEDEDLNPEQKIEREKERRMANNARERLR 589
               T S +      P Q+  +E  R  +  +  R R
Sbjct: 1404 DSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSR 1439



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 102/445 (22%), Positives = 152/445 (34%), Gaps = 60/445 (13%)

Query: 36   TRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSR--GFTDSPHYSDHLNDSRLGA 93
            +R + +G  Q SG       G++    S     S DS R  G     H+      SR G+
Sbjct: 2220 SRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGS 2279

Query: 94   HEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPG 153
                S             +  G  +  SR +G    ++S   Q       A+ SS+G+  
Sbjct: 2280 RHPRSHHE--------DRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQAR-SSAGERH 2330

Query: 154  TAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPS 213
             +++  SA SSR   +    A   ++             S +  S  S   + E  S  S
Sbjct: 2331 GSHHQQSADSSRHSGIGHGQASSAVR------------DSGHRGSSGSQASDSEGHSEDS 2378

Query: 214  PKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHD 273
                 S        Q G H  S    S+ G S     G  G S S + Q S++    S  
Sbjct: 2379 DTQSVSAHG-----QAGPHQQSHQ-ESTRGRS----AGRSGRSGSFLYQVSTHEQSES-- 2426

Query: 274  RLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSS 333
                  H  + T          S H+ +  SS      H+    G D+I G  G+++G  
Sbjct: 2427 -----AHGRTGTSTGGR---QGSHHKQARDSS-----RHSTSQEGQDTIHGHPGSSSGGR 2473

Query: 334  QTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSL 393
            Q          S +S  H S +     S      S     S+  R   Q     S + S 
Sbjct: 2474 QGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQ-----SGDGSR 2528

Query: 394  HSLQSRMEDRLDRLDDAIH--VLRNHAVGPSTSLPAGHSDIHSLLGPSHNAP----IGSL 447
            HS  SR  +   R D + H  V +  + GP TS   G S         H+       GS 
Sbjct: 2529 HS-GSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSA 2587

Query: 448  NSNYGGSSLVASSRSASMVGTHRED 472
            + N+ GS+       +    +H+ED
Sbjct: 2588 SRNHHGSAQEQLRDGSRHPRSHQED 2612



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 59/300 (19%), Positives = 94/300 (31%), Gaps = 26/300 (8%)

Query: 299 RGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPS 358
           +GS       ++ H+    G D+I G  G++ G  Q          S +S  H S +   
Sbjct: 493 QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQ 552

Query: 359 NPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHA 418
             S      S     S+  R   Q+     +  S H   S   D          V +  +
Sbjct: 553 GRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADS----SRHSQVGQGQS 608

Query: 419 VGPSTSLPAGHSDIHSLLGPSHNAP----IGSLNSNYGGSSLVASSRSASMVGTHREDSV 474
            GP TS   G S         H+       GS + N+ GS+   S   +    +H ED  
Sbjct: 609 SGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRA 668

Query: 475 SLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPP- 533
                HS  SS  + +    N  + +      Q++S        + + +  D + H    
Sbjct: 669 --GHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTG 726

Query: 534 ---------------SSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKER 578
                          SS    +D E   +D    S          +  + E   +R  ER
Sbjct: 727 HGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGER 786


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.124    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,660,564
Number of Sequences: 37866
Number of extensions: 1688774
Number of successful extensions: 10016
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 646
Number of HSP's that attempted gapping in prelim test: 8233
Number of HSP's gapped (non-prelim): 2158
length of query: 682
length of database: 18,247,518
effective HSP length: 109
effective length of query: 573
effective length of database: 14,120,124
effective search space: 8090831052
effective search space used: 8090831052
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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