BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13128864 histone deacetylase 6 [Homo sapiens] (1215 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13128864 histone deacetylase 6 [Homo sapiens] 2469 0.0 gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens] 407 e-113 gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens] 368 e-101 gi|153085395 histone deacetylase 4 [Homo sapiens] 301 2e-81 gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] 286 8e-77 gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] 286 8e-77 gi|148539870 histone deacetylase 7 isoform d [Homo sapiens] 285 1e-76 gi|169234807 histone deacetylase 7 isoform a [Homo sapiens] 285 1e-76 gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] 282 1e-75 gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens] 282 1e-75 gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens] 268 2e-71 gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens] 155 3e-37 gi|8923769 histone deacetylase 8 [Homo sapiens] 107 7e-23 gi|116284376 histone deacetylase 2 [Homo sapiens] 103 1e-21 gi|13128860 histone deacetylase 1 [Homo sapiens] 102 3e-21 gi|13128862 histone deacetylase 3 [Homo sapiens] 83 1e-15 gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens] 81 7e-15 gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens] 76 2e-13 gi|21361749 ubiquitin thioesterase 49 [Homo sapiens] 69 4e-11 gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 67 8e-11 gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 67 8e-11 gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 55 3e-07 gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 55 4e-07 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 55 5e-07 gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 55 5e-07 gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 55 5e-07 gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 55 5e-07 gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 55 5e-07 gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 55 5e-07 gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 55 5e-07 >gi|13128864 histone deacetylase 6 [Homo sapiens] Length = 1215 Score = 2469 bits (6398), Expect = 0.0 Identities = 1215/1215 (100%), Positives = 1215/1215 (100%) Query: 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG 60 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG Sbjct: 1 MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG 60 Query: 61 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI 120 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI Sbjct: 61 QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI 120 Query: 121 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS 180 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS Sbjct: 121 QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS 180 Query: 181 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ 240 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ Sbjct: 181 YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ 240 Query: 241 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG 300 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG Sbjct: 241 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG 300 Query: 301 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP 360 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP Sbjct: 301 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP 360 Query: 361 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA 420 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA Sbjct: 361 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA 420 Query: 421 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR 480 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR Sbjct: 421 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR 480 Query: 481 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH 540 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH Sbjct: 481 TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH 540 Query: 541 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN 600 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN Sbjct: 541 SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN 600 Query: 601 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF Sbjct: 601 GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660 Query: 661 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH 720 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH Sbjct: 661 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH 720 Query: 721 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG 780 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG Sbjct: 721 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG 780 Query: 781 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE 840 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE Sbjct: 781 GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE 840 Query: 841 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET 900 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET Sbjct: 841 DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET 900 Query: 901 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA 960 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA Sbjct: 901 AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA 960 Query: 961 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ 1020 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ Sbjct: 961 ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ 1020 Query: 1021 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA 1080 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA Sbjct: 1021 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA 1080 Query: 1081 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ 1140 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ Sbjct: 1081 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ 1140 Query: 1141 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN 1200 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN Sbjct: 1141 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN 1200 Query: 1201 IAHQNKFGEDMPHPH 1215 IAHQNKFGEDMPHPH Sbjct: 1201 IAHQNKFGEDMPHPH 1215 >gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens] Length = 669 Score = 407 bits (1046), Expect = e-113 Identities = 203/388 (52%), Positives = 267/388 (68%), Gaps = 8/388 (2%) Query: 85 GTGLVLDEQLNEFHCLWDDSFPE--GPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELM 142 GT LV E + LWDD E PERL A ++L Q GL RC+ AR A +EEL Sbjct: 2 GTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELG 61 Query: 143 LVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAE 202 LVHS EY+ L+ TQ + + EL+ L+ +D++Y HP+++ CA LA+G+ L+LVDAVL Sbjct: 62 LVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGA 121 Query: 203 IRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQF 262 ++NG+A++RPPGHH Q + +G+C+FN+VA+AA +A+QKH + R+L+VDWDVHHGQG Q+ Sbjct: 122 VQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQY 181 Query: 263 TFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAA 322 F+ DPSVLYFS HRYE GRFWP L+ S+ G GQG G+T+N+PWNQVGM +ADY+AA Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241 Query: 323 FLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSL 382 FLH+LLP+A EF P+LVLV+AGFD+ GDP+G+M ATP FA LT LL LAGG++ L Sbjct: 242 FLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVL 301 Query: 383 EGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRST 442 EGGY+L +LAE V ++ TLLGDP P L P APC+SA S+ A A P W+ L + Sbjct: 302 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 361 Query: 443 ETVERDNMEEDNVEESEEEGPWEPPVLP 470 T + S E P PP+LP Sbjct: 362 VTA----VPMSPSSHSPEGRP--PPLLP 383 Score = 361 bits (926), Expect = 3e-99 Identities = 188/361 (52%), Positives = 241/361 (66%), Gaps = 3/361 (0%) Query: 481 TGLVYDQNMMNHCNLWDSHHPEV--PQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538 T LVY ++M LWD E+ P+R+ + RL + GL RCL L+ R A+E EL Sbjct: 3 TALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGL 62 Query: 539 CHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEV 598 HS EYV +R T+ + EL S FD+IY PSTF CA+LA GA +LV+AVL+G V Sbjct: 63 VHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAV 122 Query: 599 LNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQH 658 NG A+VRPPGHH ++ AA GFC FN+VA+AA HA+ G RIL+VDWDVHHG G Q+ Sbjct: 123 QNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHG-LHRILVVDWDVHHGQGIQY 181 Query: 659 MFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAA 718 +FEDDPSVLY S HRY+HG F+P E + +GR G GFTVN+ WN MG+ADY+AA Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241 Query: 719 WHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILIL 778 + L+LP+A+EF+PELVLVSAGFD+A GDP G Q +PE +AHLT LL LA GR+ +L Sbjct: 242 FLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVL 301 Query: 779 EGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838 EGGY+L S++ES+ ++LLGDP P L+ P P AL SI +W+SL+ Sbjct: 302 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 361 Query: 839 V 839 V Sbjct: 362 V 362 Score = 43.1 bits (100), Expect = 0.002 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 13/85 (15%) Query: 722 LVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGG 781 LVLP+AY F P+LVLV+ G P G Q P A L +L GLA GR++ +LE Sbjct: 562 LVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRGLAGGRVLALLEE- 611 Query: 782 YNLTSISESMAACTRSLLGDPPPLL 806 S + R L G+ PP L Sbjct: 612 ---NSTPQLAGILARVLNGEAPPSL 633 Score = 41.2 bits (95), Expect = 0.006 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 15/121 (12%) Query: 319 YIAAFLHVLLPVALEFQPQLVLVAAG-FDALQGDPKGEMAATPAGFAQLTHLLMGLAGGK 377 +++ L ++LP+A FQP LVLVA G LQG +AA +L GLAGG+ Sbjct: 555 FLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAA----------MLRGLAGGR 604 Query: 378 LILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEV 437 ++ LE N G+ A L G+ P L ++ LEP W++ Sbjct: 605 VLALLE--ENSTPQLAGILA--RVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM 660 Query: 438 L 438 L Sbjct: 661 L 661 >gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens] Length = 649 Score = 368 bits (944), Expect = e-101 Identities = 190/388 (48%), Positives = 250/388 (64%), Gaps = 28/388 (7%) Query: 85 GTGLVLDEQLNEFHCLWDDSFPE--GPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELM 142 GT LV E + LWDD E PERL A ++L Q GL RC+ AR A +EEL Sbjct: 2 GTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELG 61 Query: 143 LVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAE 202 LVHS EY+ L+ TQ + + EL+ L+ +D++Y HP+++ CA LA+G+ L+LVDAVL Sbjct: 62 LVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGA 121 Query: 203 IRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQF 262 ++NG+A++RPPGHH Q + +G+C+FN+VA+AA +A+QKH + R+L+VDWDVHHGQG Q+ Sbjct: 122 VQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQY 181 Query: 263 TFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAA 322 F+ DPSVLYFS HRYE GRFWP L+ S+ G GQG G+T+N+PWNQVGM +ADY+AA Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241 Query: 323 FLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSL 382 FLH+LLP+A E G+M ATP FA LT LL LAGG++ L Sbjct: 242 FLHLLLPLAFE--------------------GQMQATPECFAHLTQLLQVLAGGRVCAVL 281 Query: 383 EGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRST 442 EGGY+L +LAE V ++ TLLGDP P L P APC+SA S+ A A P W+ L + Sbjct: 282 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 341 Query: 443 ETVERDNMEEDNVEESEEEGPWEPPVLP 470 T + S E P PP+LP Sbjct: 342 VTA----VPMSPSSHSPEGRP--PPLLP 363 Score = 318 bits (816), Expect = 2e-86 Identities = 172/361 (47%), Positives = 223/361 (61%), Gaps = 23/361 (6%) Query: 481 TGLVYDQNMMNHCNLWDSHHPEV--PQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538 T LVY ++M LWD E+ P+R+ + RL + GL RCL L+ R A+E EL Sbjct: 3 TALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGL 62 Query: 539 CHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEV 598 HS EYV +R T+ + EL S FD+IY PSTF CA+LA GA +LV+AVL+G V Sbjct: 63 VHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAV 122 Query: 599 LNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQH 658 NG A+VRPPGHH ++ AA GFC FN+VA+AA HA+ G RIL+VDWDVHHG G Q+ Sbjct: 123 QNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHG-LHRILVVDWDVHHGQGIQY 181 Query: 659 MFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAA 718 +FEDDPSVLY S HRY+HG F+P E + +GR G GFTVN+ WN MG+ADY+AA Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241 Query: 719 WHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILIL 778 + L+LP+A+E G Q +PE +AHLT LL LA GR+ +L Sbjct: 242 FLHLLLPLAFE--------------------GQMQATPECFAHLTQLLQVLAGGRVCAVL 281 Query: 779 EGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838 EGGY+L S++ES+ ++LLGDP P L+ P P AL SI +W+SL+ Sbjct: 282 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 341 Query: 839 V 839 V Sbjct: 342 V 342 Score = 43.1 bits (100), Expect = 0.002 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 13/85 (15%) Query: 722 LVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGG 781 LVLP+AY F P+LVLV+ G P G Q P A L +L GLA GR++ +LE Sbjct: 542 LVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRGLAGGRVLALLEE- 591 Query: 782 YNLTSISESMAACTRSLLGDPPPLL 806 S + R L G+ PP L Sbjct: 592 ---NSTPQLAGILARVLNGEAPPSL 613 Score = 41.2 bits (95), Expect = 0.006 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 15/121 (12%) Query: 319 YIAAFLHVLLPVALEFQPQLVLVAAG-FDALQGDPKGEMAATPAGFAQLTHLLMGLAGGK 377 +++ L ++LP+A FQP LVLVA G LQG +AA +L GLAGG+ Sbjct: 535 FLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAA----------MLRGLAGGR 584 Query: 378 LILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEV 437 ++ LE N G+ A L G+ P L ++ LEP W++ Sbjct: 585 VLALLE--ENSTPQLAGILA--RVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM 640 Query: 438 L 438 L Sbjct: 641 L 641 >gi|153085395 histone deacetylase 4 [Homo sapiens] Length = 1084 Score = 301 bits (772), Expect = 2e-81 Identities = 182/399 (45%), Positives = 235/399 (58%), Gaps = 39/399 (9%) Query: 465 EPPVLPILTWPVLQSRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELGLAGR 522 EPP P T TGLVYD M+ H C S HPE RI I RL+E GL G+ Sbjct: 645 EPPTKPRFT-------TGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGK 697 Query: 523 CLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESS------------------ 564 C + R AT EL T HS + L T + ++L + Sbjct: 698 CECIRGRKATLEELQTVHSEAHT-LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGV 756 Query: 565 NFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFN 624 + D+I+ + A+LA G LV V +GE+ NG AVVRPPGHHAE+ GFC+FN Sbjct: 757 DSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFN 816 Query: 625 SVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGD 684 SVAVAA+ Q + +ILIVDWDVHHGNGTQ F DPSVLY+SLHRYD G FFP Sbjct: 817 SVAVAAKLLQQRLSVS-KILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFP--G 873 Query: 685 EGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGF 741 GA ++G G GF VN+A+ G P MGDA+YLAA+ +V+PIA EF P++VLVS+GF Sbjct: 874 SGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGF 933 Query: 742 DAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLL 799 DA G PLGG +S + +LT LMGLA GRI+L LEGG++LT+I ++ AC +LL Sbjct: 934 DAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALL 993 Query: 800 G---DPPPLLTLPRPPLSGALASITETIQVHRRYWRSLR 835 G DP P L + P + A+ S+ + +++H +YWR L+ Sbjct: 994 GNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQ 1032 Score = 251 bits (641), Expect = 3e-66 Identities = 157/404 (38%), Positives = 219/404 (54%), Gaps = 31/404 (7%) Query: 86 TGLVLDEQLNEFHCLW--DDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143 TGLV D + + C S PE R+ +I +L + GL +C + R A EEL Sbjct: 654 TGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQT 713 Query: 144 VHSLEYIDLMETTQYMNEGELRV------LADTY------------DSVYLHPNSYSCAC 185 VHS E L+ T +N +L LA + D+++ +S A Sbjct: 714 VHS-EAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAAR 772 Query: 186 LASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIR 245 LA G V+ LV V E++NG A++RPPGHHA+ S G+C FN VAVAA+ QQ+ + Sbjct: 773 LAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVS 832 Query: 246 RVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTI 305 ++LIVDWDVHHG GTQ F DPSVLY S+HRY+ G F+P A + G G G G+ + Sbjct: 833 KILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPD--EVGTGPGVGFNV 890 Query: 306 NVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK--GEMAATP 360 N+ + M DA+Y+AAF V++P+A EF P +VLV++GFDA++G P G + Sbjct: 891 NMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSA 950 Query: 361 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLG---DPCPMLESPGAPC 417 F LT LMGLAGG+++L+LEGG++L A+ + A + LLG DP P P Sbjct: 951 RCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPN 1010 Query: 418 RSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEE 461 +A S+ +E +W L R+T T R +E E E E Sbjct: 1011 ANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAE 1054 >gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens] Length = 1123 Score = 286 bits (732), Expect = 8e-77 Identities = 176/453 (38%), Positives = 249/453 (54%), Gaps = 40/453 (8%) Query: 408 PMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPP 467 P LE PGA + + L+ L+ + L S TV + + G PP Sbjct: 618 PDLEEPGAGYKKLFSDAQ-PLQPLQVYQAPL--SLATVPHQALGRTQSSPAAPGGMKSPP 674 Query: 468 VLPILTWPVLQSRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELGLAGRCLT 525 P+ TG+VYD M+ H C ++H HPE RI I RL+E GL +C Sbjct: 675 DQPVKHL----FTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCER 730 Query: 526 LTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESS-------------------NF 566 + R AT E+ T HS EY L T + ++L + + Sbjct: 731 IRGRKATLDEIQTVHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDS 789 Query: 567 DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSV 626 D+++ + + ++A G L V +GE+ NG A++RPPGHHAE+ A GFCFFNSV Sbjct: 790 DTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSV 849 Query: 627 AVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEG 686 A+ A+ Q + ++LIVDWD+HHGNGTQ F +DPSVLY+SLHRYD+G FFP G Sbjct: 850 AITAKLLQQ-KLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP--GSG 906 Query: 687 ASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDA 743 A ++G G G+ VNVAW G P +GD +YL A+ +V+PIA+EF+P++VLVSAGFDA Sbjct: 907 APEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDA 966 Query: 744 ARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG- 800 G PLGG V+ + HLT LM LA GR++L LEGG++LT+I ++ AC +LL Sbjct: 967 VEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSV 1026 Query: 801 --DPPPLLTLPRPPLSGALASITETIQVHRRYW 831 P L + P A+A++ + I++ ++W Sbjct: 1027 ELQPLDEAVLQQKPNINAVATLEKVIEIQSKHW 1059 Score = 235 bits (599), Expect = 2e-61 Identities = 147/404 (36%), Positives = 213/404 (52%), Gaps = 33/404 (8%) Query: 86 TGLVLDEQLNEFHCLWDDSF--PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143 TG+V D + + C+ ++ PE R+ +I +L + GLL +C + R A +E+ Sbjct: 684 TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQT 743 Query: 144 VHSLEYIDLMETTQYMNEGELRV-------------------LADTYDSVYLHPNSYSCA 184 VHS EY L+ T +N +L + D+V+ +S S Sbjct: 744 VHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV 802 Query: 185 CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244 +A G +L L V E++NG AIIRPPGHHA+ S G+C FN VA+ A+ QQK + Sbjct: 803 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV 862 Query: 245 RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304 +VLIVDWD+HHG GTQ F DPSVLY S+HRY+ G F+P A G G G GY Sbjct: 863 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAP--EEVGGGPGVGYN 920 Query: 305 INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMAAT 359 +NV W + D +Y+ AF V++P+A EF P +VLV+AGFDA++G P G + T Sbjct: 921 VNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVT 980 Query: 360 PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLG---DPCPMLESPGAP 416 F LT LM LAGG+++L+LEGG++L A+ + A + LL P P Sbjct: 981 ARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKP 1040 Query: 417 CRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEE 460 +A A++ +E W + + + R ++ E E+EE Sbjct: 1041 NINAVATLEKVIEIQSKHWSCVQKFAAGLGR-SLREAQAGETEE 1083 >gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens] Length = 1122 Score = 286 bits (732), Expect = 8e-77 Identities = 176/453 (38%), Positives = 249/453 (54%), Gaps = 40/453 (8%) Query: 408 PMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPP 467 P LE PGA + + L+ L+ + L S TV + + G PP Sbjct: 617 PDLEEPGAGYKKLFSDAQ-PLQPLQVYQAPL--SLATVPHQALGRTQSSPAAPGGMKSPP 673 Query: 468 VLPILTWPVLQSRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELGLAGRCLT 525 P+ TG+VYD M+ H C ++H HPE RI I RL+E GL +C Sbjct: 674 DQPVKHL----FTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCER 729 Query: 526 LTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESS-------------------NF 566 + R AT E+ T HS EY L T + ++L + + Sbjct: 730 IRGRKATLDEIQTVHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDS 788 Query: 567 DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSV 626 D+++ + + ++A G L V +GE+ NG A++RPPGHHAE+ A GFCFFNSV Sbjct: 789 DTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSV 848 Query: 627 AVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEG 686 A+ A+ Q + ++LIVDWD+HHGNGTQ F +DPSVLY+SLHRYD+G FFP G Sbjct: 849 AITAKLLQQ-KLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP--GSG 905 Query: 687 ASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDA 743 A ++G G G+ VNVAW G P +GD +YL A+ +V+PIA+EF+P++VLVSAGFDA Sbjct: 906 APEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDA 965 Query: 744 ARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG- 800 G PLGG V+ + HLT LM LA GR++L LEGG++LT+I ++ AC +LL Sbjct: 966 VEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSV 1025 Query: 801 --DPPPLLTLPRPPLSGALASITETIQVHRRYW 831 P L + P A+A++ + I++ ++W Sbjct: 1026 ELQPLDEAVLQQKPNINAVATLEKVIEIQSKHW 1058 Score = 235 bits (599), Expect = 2e-61 Identities = 147/404 (36%), Positives = 213/404 (52%), Gaps = 33/404 (8%) Query: 86 TGLVLDEQLNEFHCLWDDSF--PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143 TG+V D + + C+ ++ PE R+ +I +L + GLL +C + R A +E+ Sbjct: 683 TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQT 742 Query: 144 VHSLEYIDLMETTQYMNEGELRV-------------------LADTYDSVYLHPNSYSCA 184 VHS EY L+ T +N +L + D+V+ +S S Sbjct: 743 VHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV 801 Query: 185 CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244 +A G +L L V E++NG AIIRPPGHHA+ S G+C FN VA+ A+ QQK + Sbjct: 802 RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV 861 Query: 245 RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304 +VLIVDWD+HHG GTQ F DPSVLY S+HRY+ G F+P A G G G GY Sbjct: 862 GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAP--EEVGGGPGVGYN 919 Query: 305 INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMAAT 359 +NV W + D +Y+ AF V++P+A EF P +VLV+AGFDA++G P G + T Sbjct: 920 VNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVT 979 Query: 360 PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLG---DPCPMLESPGAP 416 F LT LM LAGG+++L+LEGG++L A+ + A + LL P P Sbjct: 980 ARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKP 1039 Query: 417 CRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEE 460 +A A++ +E W + + + R ++ E E+EE Sbjct: 1040 NINAVATLEKVIEIQSKHWSCVQKFAAGLGR-SLREAQAGETEE 1082 >gi|148539870 histone deacetylase 7 isoform d [Homo sapiens] Length = 954 Score = 285 bits (730), Expect = 1e-76 Identities = 174/380 (45%), Positives = 222/380 (58%), Gaps = 33/380 (8%) Query: 481 TGLVYDQNMMNH-CNLWD-SHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538 TGL+YD M+ H C+ D S HPE RI I RL+E GL +C L R A+ EL + Sbjct: 522 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 581 Query: 539 CHSAEYVGHLRATEKMKTRELHRESS-------------------NFDSIYICPSTFACA 579 HS +V L T + +L + D+I+ + A Sbjct: 582 VHSERHV-LLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAA 640 Query: 580 QLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGH 639 + A G+ L V S E+ NG AVVRPPGHHA+ A GFCFFNSVA+A R Q S Sbjct: 641 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQS-K 699 Query: 640 ALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGF 699 A +ILIVDWDVHHGNGTQ F DPSVLY+SLHR+D G FFP GA ++G +G GF Sbjct: 700 ASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFP--GSGAVDEVGAGSGEGF 757 Query: 700 TVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGD--PLGGCQV 754 VNVAW G P MGD +YLAA+ +V+PIA EF+P+LVLVSAGFDAA G PLGG V Sbjct: 758 NVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHV 817 Query: 755 SPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG---DPPPLLTLPRP 811 S + + ++T LM LA G ++L LEGG++LT+I ++ AC +LLG DP + Sbjct: 818 SAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQK 877 Query: 812 PLSGALASITETIQVHRRYW 831 P A+ S+ I+VH +YW Sbjct: 878 PNLNAIRSLEAVIRVHSKYW 897 Score = 242 bits (617), Expect = 2e-63 Identities = 147/384 (38%), Positives = 209/384 (54%), Gaps = 32/384 (8%) Query: 86 TGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143 TGL+ D + + C D+ PE R+ +I +L + GL +C + R A EEL Sbjct: 522 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 581 Query: 144 VHSLEYIDLMETTQY----MNEGELRVL---------------ADTYDSVYLHPNSYSCA 184 VHS ++ L T ++ G+L L DT D+++ +S + A Sbjct: 582 VHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDT-DTIWNELHSSNAA 640 Query: 185 CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244 A+GSV L V E++NG A++RPPGHHA HS G+C FN VA+A R QQ+ + Sbjct: 641 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKA 700 Query: 245 RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304 ++LIVDWDVHHG GTQ TF QDPSVLY S+HR++ G F+P A + G G G+G+ Sbjct: 701 SKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVD--EVGAGSGEGFN 758 Query: 305 INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK--GEMAAT 359 +NV W M D +Y+AAF V++P+A EF P LVLV+AGFDA +G P G + Sbjct: 759 VNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS 818 Query: 360 PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPG---AP 416 F +T LM LAGG ++L+LEGG++L A+ + A + LLG+ L G P Sbjct: 819 AKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKP 878 Query: 417 CRSAQASVSCALEALEPFWEVLVR 440 +A S+ + +W + R Sbjct: 879 NLNAIRSLEAVIRVHSKYWGCMQR 902 >gi|169234807 histone deacetylase 7 isoform a [Homo sapiens] Length = 991 Score = 285 bits (730), Expect = 1e-76 Identities = 174/380 (45%), Positives = 222/380 (58%), Gaps = 33/380 (8%) Query: 481 TGLVYDQNMMNH-CNLWD-SHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538 TGL+YD M+ H C+ D S HPE RI I RL+E GL +C L R A+ EL + Sbjct: 559 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 618 Query: 539 CHSAEYVGHLRATEKMKTRELHRESS-------------------NFDSIYICPSTFACA 579 HS +V L T + +L + D+I+ + A Sbjct: 619 VHSERHV-LLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAA 677 Query: 580 QLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGH 639 + A G+ L V S E+ NG AVVRPPGHHA+ A GFCFFNSVA+A R Q S Sbjct: 678 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQS-K 736 Query: 640 ALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGF 699 A +ILIVDWDVHHGNGTQ F DPSVLY+SLHR+D G FFP GA ++G +G GF Sbjct: 737 ASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFP--GSGAVDEVGAGSGEGF 794 Query: 700 TVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGD--PLGGCQV 754 VNVAW G P MGD +YLAA+ +V+PIA EF+P+LVLVSAGFDAA G PLGG V Sbjct: 795 NVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHV 854 Query: 755 SPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG---DPPPLLTLPRP 811 S + + ++T LM LA G ++L LEGG++LT+I ++ AC +LLG DP + Sbjct: 855 SAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQK 914 Query: 812 PLSGALASITETIQVHRRYW 831 P A+ S+ I+VH +YW Sbjct: 915 PNLNAIRSLEAVIRVHSKYW 934 Score = 242 bits (617), Expect = 2e-63 Identities = 147/384 (38%), Positives = 209/384 (54%), Gaps = 32/384 (8%) Query: 86 TGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143 TGL+ D + + C D+ PE R+ +I +L + GL +C + R A EEL Sbjct: 559 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 618 Query: 144 VHSLEYIDLMETTQY----MNEGELRVL---------------ADTYDSVYLHPNSYSCA 184 VHS ++ L T ++ G+L L DT D+++ +S + A Sbjct: 619 VHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDT-DTIWNELHSSNAA 677 Query: 185 CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244 A+GSV L V E++NG A++RPPGHHA HS G+C FN VA+A R QQ+ + Sbjct: 678 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKA 737 Query: 245 RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304 ++LIVDWDVHHG GTQ TF QDPSVLY S+HR++ G F+P A + G G G+G+ Sbjct: 738 SKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVD--EVGAGSGEGFN 795 Query: 305 INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK--GEMAAT 359 +NV W M D +Y+AAF V++P+A EF P LVLV+AGFDA +G P G + Sbjct: 796 VNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS 855 Query: 360 PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPG---AP 416 F +T LM LAGG ++L+LEGG++L A+ + A + LLG+ L G P Sbjct: 856 AKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKP 915 Query: 417 CRSAQASVSCALEALEPFWEVLVR 440 +A S+ + +W + R Sbjct: 916 NLNAIRSLEAVIRVHSKYWGCMQR 939 >gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] Length = 1069 Score = 282 bits (722), Expect = 1e-75 Identities = 169/408 (41%), Positives = 234/408 (57%), Gaps = 39/408 (9%) Query: 467 PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518 P +L P + S TG+ YD M+ H C +S HPE RI I RL+E G Sbjct: 616 PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 675 Query: 519 LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572 L +C + R A+ E+ HS E+ L T + ++L +S F S C Sbjct: 676 LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 734 Query: 573 PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619 + A++A G L V SGE+ NG AVVRPPGHHAE+ A G Sbjct: 735 GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 794 Query: 620 FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679 FCFFNSVA+ A++ + + +ILIVD DVHHGNGTQ F DPS+LY+SLHRYD G F Sbjct: 795 FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 853 Query: 680 FPMGDEGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVL 736 FP GA +++G G G+ +N+AW G P MGD +YL A+ +V P+A EF+P++VL Sbjct: 854 FP--GSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVL 911 Query: 737 VSAGFDAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAAC 794 VSAGFDA G PLGG +V+ + + HLT LM LA GR++L LEGG++LT+I ++ AC Sbjct: 912 VSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEAC 971 Query: 795 TRSLLG---DPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKV 839 +LLG +P L + P A+ S+ + I++ +YW+S+R++ V Sbjct: 972 VNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSKYWKSVRMVAV 1019 Score = 236 bits (603), Expect = 8e-62 Identities = 143/382 (37%), Positives = 212/382 (55%), Gaps = 32/382 (8%) Query: 84 AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141 + TG+ D + + C+ +S PE R+ +I +L + GLL++C Q R A EE+ Sbjct: 634 SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 693 Query: 142 MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182 LVHS E+ L+ T ++ +L R+L D+++ +S Sbjct: 694 QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 752 Query: 183 CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242 A +A G V+ L V E++NG A++RPPGHHA+ S G+C FN VA+ A+Y + + Sbjct: 753 AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 812 Query: 243 RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQG 302 I ++LIVD DVHHG GTQ F DPS+LY S+HRY++G F+P A N G G G+G Sbjct: 813 NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGTGLGEG 870 Query: 303 YTINVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMA 357 Y IN+ W M D +Y+ AF ++ PVA EF P +VLV+AGFDAL+G P G Sbjct: 871 YNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYK 930 Query: 358 ATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPC-PMLES--PG 414 T F LT LM LA G+++L+LEGG++L A+ + A ++ LLG+ P+ E Sbjct: 931 VTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQ 990 Query: 415 APCRSAQASVSCALEALEPFWE 436 +P +A S+ +E +W+ Sbjct: 991 SPNMNAVISLQKIIEIQSKYWK 1012 >gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens] Length = 1066 Score = 282 bits (722), Expect = 1e-75 Identities = 169/408 (41%), Positives = 234/408 (57%), Gaps = 39/408 (9%) Query: 467 PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518 P +L P + S TG+ YD M+ H C +S HPE RI I RL+E G Sbjct: 613 PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 672 Query: 519 LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572 L +C + R A+ E+ HS E+ L T + ++L +S F S C Sbjct: 673 LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 731 Query: 573 PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619 + A++A G L V SGE+ NG AVVRPPGHHAE+ A G Sbjct: 732 GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 791 Query: 620 FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679 FCFFNSVA+ A++ + + +ILIVD DVHHGNGTQ F DPS+LY+SLHRYD G F Sbjct: 792 FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 850 Query: 680 FPMGDEGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVL 736 FP GA +++G G G+ +N+AW G P MGD +YL A+ +V P+A EF+P++VL Sbjct: 851 FP--GSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVL 908 Query: 737 VSAGFDAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAAC 794 VSAGFDA G PLGG +V+ + + HLT LM LA GR++L LEGG++LT+I ++ AC Sbjct: 909 VSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEAC 968 Query: 795 TRSLLG---DPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKV 839 +LLG +P L + P A+ S+ + I++ +YW+S+R++ V Sbjct: 969 VNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSKYWKSVRMVAV 1016 Score = 236 bits (603), Expect = 8e-62 Identities = 143/382 (37%), Positives = 212/382 (55%), Gaps = 32/382 (8%) Query: 84 AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141 + TG+ D + + C+ +S PE R+ +I +L + GLL++C Q R A EE+ Sbjct: 631 SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 690 Query: 142 MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182 LVHS E+ L+ T ++ +L R+L D+++ +S Sbjct: 691 QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 749 Query: 183 CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242 A +A G V+ L V E++NG A++RPPGHHA+ S G+C FN VA+ A+Y + + Sbjct: 750 AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 809 Query: 243 RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQG 302 I ++LIVD DVHHG GTQ F DPS+LY S+HRY++G F+P A N G G G+G Sbjct: 810 NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGTGLGEG 867 Query: 303 YTINVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMA 357 Y IN+ W M D +Y+ AF ++ PVA EF P +VLV+AGFDAL+G P G Sbjct: 868 YNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYK 927 Query: 358 ATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPC-PMLES--PG 414 T F LT LM LA G+++L+LEGG++L A+ + A ++ LLG+ P+ E Sbjct: 928 VTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQ 987 Query: 415 APCRSAQASVSCALEALEPFWE 436 +P +A S+ +E +W+ Sbjct: 988 SPNMNAVISLQKIIEIQSKYWK 1009 >gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens] Length = 1011 Score = 268 bits (686), Expect = 2e-71 Identities = 164/395 (41%), Positives = 224/395 (56%), Gaps = 39/395 (9%) Query: 467 PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518 P +L P + S TG+ YD M+ H C +S HPE RI I RL+E G Sbjct: 613 PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 672 Query: 519 LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572 L +C + R A+ E+ HS E+ L T + ++L +S F S C Sbjct: 673 LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 731 Query: 573 PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619 + A++A G L V SGE+ NG AVVRPPGHHAE+ A G Sbjct: 732 GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 791 Query: 620 FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679 FCFFNSVA+ A++ + + +ILIVD DVHHGNGTQ F DPS+LY+SLHRYD G F Sbjct: 792 FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 850 Query: 680 FPMGDEGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVL 736 FP GA +++G G G+ +N+AW G P MGD +YL A+ +V P+A EF+P++VL Sbjct: 851 FP--GSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVL 908 Query: 737 VSAGFDAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAAC 794 VSAGFDA G PLGG +V+ + + HLT LM LA GR++L LEGG++LT+I ++ AC Sbjct: 909 VSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEAC 968 Query: 795 TRSLLG---DPPPLLTLPRPPLSGALASITETIQV 826 +LLG +P L + P A+ S+ + I++ Sbjct: 969 VNALLGNELEPLAEDILHQSPNMNAVISLQKIIEI 1003 Score = 234 bits (596), Expect = 5e-61 Identities = 136/348 (39%), Positives = 198/348 (56%), Gaps = 29/348 (8%) Query: 84 AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141 + TG+ D + + C+ +S PE R+ +I +L + GLL++C Q R A EE+ Sbjct: 631 SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 690 Query: 142 MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182 LVHS E+ L+ T ++ +L R+L D+++ +S Sbjct: 691 QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 749 Query: 183 CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242 A +A G V+ L V E++NG A++RPPGHHA+ S G+C FN VA+ A+Y + + Sbjct: 750 AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 809 Query: 243 RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQG 302 I ++LIVD DVHHG GTQ F DPS+LY S+HRY++G F+P A N G G G+G Sbjct: 810 NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGTGLGEG 867 Query: 303 YTINVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMA 357 Y IN+ W M D +Y+ AF ++ PVA EF P +VLV+AGFDAL+G P G Sbjct: 868 YNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYK 927 Query: 358 ATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGD 405 T F LT LM LA G+++L+LEGG++L A+ + A ++ LLG+ Sbjct: 928 VTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGN 975 >gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens] Length = 879 Score = 155 bits (391), Expect = 3e-37 Identities = 101/252 (40%), Positives = 132/252 (52%), Gaps = 31/252 (12%) Query: 467 PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518 P +L P + S TG+ YD M+ H C +S HPE RI I RL+E G Sbjct: 613 PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 672 Query: 519 LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572 L +C + R A+ E+ HS E+ L T + ++L +S F S C Sbjct: 673 LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 731 Query: 573 PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619 + A++A G L V SGE+ NG AVVRPPGHHAE+ A G Sbjct: 732 GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 791 Query: 620 FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679 FCFFNSVA+ A++ + + +ILIVD DVHHGNGTQ F DPS+LY+SLHRYD G F Sbjct: 792 FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 850 Query: 680 FPMGDEGASSQI 691 FP GA +++ Sbjct: 851 FP--GSGAPNEV 860 Score = 149 bits (376), Expect = 2e-35 Identities = 85/229 (37%), Positives = 127/229 (55%), Gaps = 22/229 (9%) Query: 84 AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141 + TG+ D + + C+ +S PE R+ +I +L + GLL++C Q R A EE+ Sbjct: 631 SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 690 Query: 142 MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182 LVHS E+ L+ T ++ +L R+L D+++ +S Sbjct: 691 QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 749 Query: 183 CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242 A +A G V+ L V E++NG A++RPPGHHA+ S G+C FN VA+ A+Y + + Sbjct: 750 AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 809 Query: 243 RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASN 291 I ++LIVD DVHHG GTQ F DPS+LY S+HRY++G F+P A N Sbjct: 810 NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN 858 >gi|8923769 histone deacetylase 8 [Homo sapiens] Length = 377 Score = 107 bits (267), Expect = 7e-23 Identities = 84/303 (27%), Positives = 137/303 (45%), Gaps = 15/303 (4%) Query: 502 EVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR 561 ++P+R + +E L + + P+ A+ E+ T H+ Y+ HL+ + + H Sbjct: 33 KIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HP 91 Query: 562 ESSNFDSIYICPST---FACAQLATGAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQDAA 617 +S + Y CP+T F A GA + ++ G + A+ G HHA++D A Sbjct: 92 DSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDG--MCKVAINWSGGWHHAKKDEA 149 Query: 618 CGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHG 677 GFC+ N + + RIL VD D+HHG+G + F V+ VSLH++ G Sbjct: 150 SGFCYLNDAVLGILRLRR---KFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG 206 Query: 678 TFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLV 737 FFP G S +G G ++VNV + D Y ++ + FNP+ V++ Sbjct: 207 -FFP--GTGDVSDVGLGKGRYYSVNVPIQ-DGIQDEKYYQICESVLKEVYQAFNPKAVVL 262 Query: 738 SAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRS 797 G D GDP+ ++P G ++ +IL GGYNL + + T Sbjct: 263 QLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLIL-GGGGYNLANTARCWTYLTGV 321 Query: 798 LLG 800 +LG Sbjct: 322 ILG 324 Score = 91.7 bits (226), Expect = 4e-18 Identities = 77/300 (25%), Positives = 123/300 (41%), Gaps = 34/300 (11%) Query: 103 DSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEG 162 DS + P+R + + L + + + A EE+ H+ Y+ ++ + Sbjct: 29 DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDD 88 Query: 163 ELRVLADTYDSVYLHPNSYSCA----CLASGSVLRLVDAVLGAEIRNGMAII-------- 210 + HP+S C A+ + A+ GA I +I Sbjct: 89 D-------------HPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135 Query: 211 --RPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDP 268 HHA+ G+C N + ++K R+L VD D+HHG G + F Sbjct: 136 NWSGGWHHAKKDEASGFCYLNDAVLGILRLRRK--FERILYVDLDLHHGDGVEDAFSFTS 193 Query: 269 SVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLL 328 V+ S+H++ G F+P + S G G+G+ Y++NVP Q G++D Y VL Sbjct: 194 KVMTVSLHKFSPG-FFP--GTGDVSDVGLGKGRYYSVNVP-IQDGIQDEKYYQICESVLK 249 Query: 329 PVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNL 388 V F P+ V++ G D + GDP TP G + ++ LIL GGYNL Sbjct: 250 EVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILG-GGGYNL 308 >gi|116284376 histone deacetylase 2 [Homo sapiens] Length = 582 Score = 103 bits (256), Expect = 1e-21 Identities = 88/332 (26%), Positives = 145/332 (43%), Gaps = 23/332 (6%) Query: 467 PVLPILTWPVLQSRTG------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLA 520 PV + P+ S+ G YD ++ N+ + HP P RI L GL Sbjct: 86 PVAAVAGEPMAYSQGGGKKKVCYYYDGDIGNY--YYGQGHPMKPHRIRMTHNLLLNYGLY 143 Query: 521 GRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICP---STFA 577 + P AT E+ HS EY+ LR+ E ++ F+ CP F Sbjct: 144 RKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFE 203 Query: 578 CAQLATGAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTI 636 QL+TG + + AV AV G HHA++ A GFC+ N + +A + + Sbjct: 204 FCQLSTGGS--VAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAI--LELL 259 Query: 637 SGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAG 696 H R+L +D D+HHG+G + F V+ VS H+Y G +FP G IG G Sbjct: 260 KYHQ-RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFP--GTGDLRDIGAGKG 314 Query: 697 TGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSP 756 + VN + D Y + ++ + + P V++ G D+ GD LG ++ Sbjct: 315 KYYAVNFPMR-DGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTV 373 Query: 757 EGYAHLTHLLMGLASGRIILILEGGYNLTSIS 788 +G+A ++ + ++++ GGY + +++ Sbjct: 374 KGHAKCVEVVKTF-NLPLLMLGGGGYTIRNVA 404 Score = 92.0 bits (227), Expect = 3e-18 Identities = 81/292 (27%), Positives = 123/292 (42%), Gaps = 16/292 (5%) Query: 106 PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELR 165 P P R+ L+ GL + ++ A EE+ HS EYI + + + N E Sbjct: 124 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYS 183 Query: 166 VLADTY----DSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHS 220 + D C GSV AV + MA+ G HHA+ S Sbjct: 184 KQMQRFNVGEDCPVFDGLFEFCQLSTGGSV---AGAVKLNRQQTDMAVNWAGGLHHAKKS 240 Query: 221 LMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQ 280 G+C N + +A + H+ RVL +D D+HHG G + F V+ S H+Y Sbjct: 241 EASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY-- 296 Query: 281 GRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVL 340 G ++P + G G+G+ Y +N P G+ D Y F ++ V +QP V+ Sbjct: 297 GEYFP--GTGDLRDIGAGKGKYYAVNFPMRD-GIDDESYGQIFKPIISKVMEMYQPSAVV 353 Query: 341 VAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALA 392 + G D+L GD G T G A+ ++ L+L GGY +R +A Sbjct: 354 LQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG-GGGYTIRNVA 404 >gi|13128860 histone deacetylase 1 [Homo sapiens] Length = 482 Score = 102 bits (253), Expect = 3e-21 Identities = 83/308 (26%), Positives = 137/308 (44%), Gaps = 17/308 (5%) Query: 485 YDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEY 544 YD ++ N+ + HP P RI L GL + P A E+ HS +Y Sbjct: 15 YDGDVGNY--YYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDY 72 Query: 545 VGHLRATEKMKTRELHRESSNFDSIYICP---STFACAQLATGAACRLVEAVLSGEVLNG 601 + LR+ E ++ F+ CP F QL+TG + + AV + Sbjct: 73 IKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGS--VASAVKLNKQQTD 130 Query: 602 AAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660 AV G HHA++ A GFC+ N + +A + + H R+L +D D+HHG+G + F Sbjct: 131 IAVNWAGGLHHAKKSEASGFCYVNDIVLAI--LELLKYHQ-RVLYIDIDIHHGDGVEEAF 187 Query: 661 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH 720 V+ VS H+Y G +FP G IG G + VN + D Y A + Sbjct: 188 YTTDRVMTVSFHKY--GEYFP--GTGDLRDIGAGKGKYYAVNYPLR-DGIDDESYEAIFK 242 Query: 721 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG 780 ++ + F P V++ G D+ GD LG ++ +G+A + + ++++ G Sbjct: 243 PVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSF-NLPMLMLGGG 301 Query: 781 GYNLTSIS 788 GY + +++ Sbjct: 302 GYTIRNVA 309 Score = 94.4 bits (233), Expect = 6e-19 Identities = 82/292 (28%), Positives = 124/292 (42%), Gaps = 16/292 (5%) Query: 106 PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELR 165 P P R+ L+ GL + ++ A EE+ HS +YI + + + N E Sbjct: 29 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYS 88 Query: 166 VLADTY----DSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHS 220 + D C GSV AV + + +A+ G HHA+ S Sbjct: 89 KQMQRFNVGEDCPVFDGLFEFCQLSTGGSV---ASAVKLNKQQTDIAVNWAGGLHHAKKS 145 Query: 221 LMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQ 280 G+C N + +A + H+ RVL +D D+HHG G + F V+ S H+Y Sbjct: 146 EASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY-- 201 Query: 281 GRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVL 340 G ++P + G G+G+ Y +N P G+ D Y A F V+ V FQP V+ Sbjct: 202 GEYFP--GTGDLRDIGAGKGKYYAVNYPLRD-GIDDESYEAIFKPVMSKVMEMFQPSAVV 258 Query: 341 VAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALA 392 + G D+L GD G T G A+ + L+L GGY +R +A Sbjct: 259 LQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLG-GGGYTIRNVA 309 >gi|13128862 histone deacetylase 3 [Homo sapiens] Length = 428 Score = 83.2 bits (204), Expect = 1e-15 Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 12/292 (4%) Query: 500 HPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTREL 559 HP P R+ + GL + + P A++ ++ HS +Y+ L+ + Sbjct: 22 HPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGF 81 Query: 560 HRESSNF---DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDA 616 + + F D + P F TGA+ + L+ ++ + A HHA++ Sbjct: 82 TKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQ-LNNKICDIAINWAGGLHHAKKFE 140 Query: 617 ACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDH 676 A GFC+ N + + + + H R+L +D D+HHG+G Q F V+ VS H+Y + Sbjct: 141 ASGFCYVNDIVIGI--LELLKYHP-RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN 197 Query: 677 GTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVL 736 FFP G ++G +G + +NV + D Y + ++ + + P ++ Sbjct: 198 -YFFP--GTGDMYEVGAESGRYYCLNVPLR-DGIDDQSYKHLFQPVINQVVDFYQPTCIV 253 Query: 737 VSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSIS 788 + G D+ D LG +S G+ + + ++++ GGY + +++ Sbjct: 254 LQCGADSLGCDRLGCFNLSIRGHGECVEYVKSF-NIPLLVLGGGGYTVRNVA 304 Score = 78.2 bits (191), Expect = 4e-14 Identities = 74/311 (23%), Positives = 124/311 (39%), Gaps = 25/311 (8%) Query: 91 DEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYI 150 D + FH + P P RL ++ GL + + F+ A + ++ HS +YI Sbjct: 10 DPDVGNFH--YGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYI 67 Query: 151 DLMET---------TQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGA 201 D ++ T+ +N + + ++ + Y+ A L + L + Sbjct: 68 DFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAI 127 Query: 202 EIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQ 261 G+ HHA+ G+C N + + + H RVL +D D+HHG G Q Sbjct: 128 NWAGGL-------HHAKKFEASGFCYVNDIVIGILELLKYHP--RVLYIDIDIHHGDGVQ 178 Query: 262 FTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIA 321 F V+ S H+Y F+P + G G+ Y +NVP G+ D Y Sbjct: 179 EAFYLTDRVMTVSFHKY-GNYFFP--GTGDMYEVGAESGRYYCLNVPLRD-GIDDQSYKH 234 Query: 322 AFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILS 381 F V+ V +QP +++ G D+L D G + G + + L+L Sbjct: 235 LFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLG 294 Query: 382 LEGGYNLRALA 392 GGY +R +A Sbjct: 295 -GGGYTVRNVA 304 >gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens] Length = 347 Score = 80.9 bits (198), Expect = 7e-15 Identities = 79/320 (24%), Positives = 131/320 (40%), Gaps = 32/320 (10%) Query: 469 LPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTP 528 +P WP++ S Y+ M L HP + +++ L+E L + + Sbjct: 11 VPETRWPIVYSPR---YNITFMGLEKL----HPFDAGKWGKVINFLKEEKLLSDSMLVEA 63 Query: 529 RPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACR 588 R A+E +LL H+ Y+ L+ + + T + + P+ ++ + Sbjct: 64 REASEEDLLVVHTRRYLNELKWSFAVAT------ITEIPPVIFLPNFLVQRKVLRPLRTQ 117 Query: 589 LVEAVLSGE--VLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILI 645 +++G+ V G A+ G HH D GFC + + +A + R I Sbjct: 118 TGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATI 177 Query: 646 VDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAW 705 +D D H GNG + F DD V + ++ +P GD A I R V + W Sbjct: 178 IDLDAHQGNGHERDFMDDKRVYIMDVYNRH---IYP-GDRFAKQAIRRK------VELEW 227 Query: 706 NGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHL 765 D +YL R + E P++V+ +AG D GD LGG +SP G L Sbjct: 228 GTE---DDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDEL 284 Query: 766 LMGLASGR---IILILEGGY 782 + + GR I+++ GGY Sbjct: 285 VFRMVRGRRVPILMVTSGGY 304 Score = 70.5 bits (171), Expect = 9e-12 Identities = 82/320 (25%), Positives = 128/320 (40%), Gaps = 46/320 (14%) Query: 119 LIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHP 178 L +E LL + +AR A +E+L++VH T +Y+NE + T + P Sbjct: 49 LKEEKLLSDSMLVEAREASEEDLLVVH---------TRRYLNELKWSFAVATITEI--PP 97 Query: 179 NSYSCACLASGSVLRLVDAVLGAEI-------RNGMAIIRPPG-HHAQHSLMDGYCMFNH 230 + L VLR + G I G AI G HH G+C + Sbjct: 98 VIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYAD 157 Query: 231 VAVAARYAQQK-HRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSI---HRYEQGRFWPH 286 + +A ++ ++ I R I+D D H G G + F D V + H Y RF Sbjct: 158 ITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAK- 216 Query: 287 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD 346 Q + + W G D +Y+ + E P +V+ AG D Sbjct: 217 ------------QAIRRKVELEW---GTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTD 261 Query: 347 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGK---LILSLEGGYNLRALAEGVSASLHTLL 403 L+GD G ++ +PAG + L+ + G+ +++ GGY R A ++ S+ L Sbjct: 262 ILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRT-ARIIADSILNLF 320 Query: 404 GDPCPMLESPGAPCRSAQAS 423 G L P +P SAQ S Sbjct: 321 G---LGLIGPESPSVSAQNS 337 >gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens] Length = 296 Score = 75.9 bits (185), Expect = 2e-13 Identities = 74/286 (25%), Positives = 114/286 (39%), Gaps = 42/286 (14%) Query: 500 HPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTREL 559 HP + +++ L+E L + + R A+E +LL H+ Y+ L+ + R L Sbjct: 7 HPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELK---RKVLRPL 63 Query: 560 HRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619 ++ T +LA V G +N V HH D G Sbjct: 64 RTQTGG---------TIMAGKLA----------VERGWAIN----VGGGFHHCSSDRGGG 100 Query: 620 FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679 FC + + +A + R I+D D H GNG + F DD V + ++ Sbjct: 101 FCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRH---I 157 Query: 680 FPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSA 739 +P GD A I R V + W D +YL R + E P++V+ +A Sbjct: 158 YP-GDRFAKQAIRRK------VELEWGTE---DDEYLDKVERNIKKSLQEHLPDVVVYNA 207 Query: 740 GFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGR---IILILEGGY 782 G D GD LGG +SP G L+ + GR I+++ GGY Sbjct: 208 GTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGY 253 Score = 68.2 bits (165), Expect = 5e-11 Identities = 77/313 (24%), Positives = 127/313 (40%), Gaps = 55/313 (17%) Query: 119 LIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHP 178 L +E LL + +AR A +E+L++VH T +Y+NE + +VL Sbjct: 21 LKEEKLLSDSMLVEAREASEEDLLVVH---------TRRYLNELKRKVLRPL-------- 63 Query: 179 NSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHSLMDGYCMFNHVAVAARY 237 + + + +G + + G AI G HH G+C + + +A ++ Sbjct: 64 RTQTGGTIMAGKLA----------VERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKF 113 Query: 238 AQQK-HRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSI---HRYEQGRFWPHLKASNWS 293 ++ I R I+D D H G G + F D V + H Y RF Sbjct: 114 LFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAK-------- 165 Query: 294 TTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK 353 Q + + W G D +Y+ + E P +V+ AG D L+GD Sbjct: 166 -----QAIRRKVELEW---GTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRL 217 Query: 354 GEMAATPAGFAQLTHLLMGLAGGK---LILSLEGGYNLRALAEGVSASLHTLLGDPCPML 410 G ++ +PAG + L+ + G+ +++ GGY R A ++ S+ L G L Sbjct: 218 GGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRT-ARIIADSILNLFG---LGL 273 Query: 411 ESPGAPCRSAQAS 423 P +P SAQ S Sbjct: 274 IGPESPSVSAQNS 286 >gi|21361749 ubiquitin thioesterase 49 [Homo sapiens] Length = 640 Score = 68.6 bits (166), Expect = 4e-11 Identities = 27/58 (46%), Positives = 34/58 (58%) Query: 1133 CGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYV 1190 C +C T + W CL C V CGRYI H L+H +GHPL + DL +CY C+ YV Sbjct: 26 CLECATTESVWACLKCSHVACGRYIEDHALKHFEETGHPLAMEVRDLYVFCYLCKDYV 83 >gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] Length = 712 Score = 67.4 bits (163), Expect = 8e-11 Identities = 27/58 (46%), Positives = 33/58 (56%) Query: 1133 CGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYV 1190 C DC T + W CLSC V CGRYI H L+H S HP+ L ++ +CY C YV Sbjct: 29 CVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86 >gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] Length = 712 Score = 67.4 bits (163), Expect = 8e-11 Identities = 27/58 (46%), Positives = 33/58 (56%) Query: 1133 CGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYV 1190 C DC T + W CLSC V CGRYI H L+H S HP+ L ++ +CY C YV Sbjct: 29 CVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86 >gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] Length = 1542 Score = 55.5 bits (132), Expect = 3e-07 Identities = 47/171 (27%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G EST SET V++T + + + G+ T + T SE + Sbjct: 99 VSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 158 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 159 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 214 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 215 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 265 Score = 53.5 bits (127), Expect = 1e-06 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%) Query: 881 KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935 ++T+AS G E+T T SET + + + A+T G+ T + T SE + M Sbjct: 742 EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 801 Query: 936 QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983 +TT +G T +T SE T+ +TT+ G T+ +T+ Sbjct: 802 ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 859 Query: 984 AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039 G+ TTS E T SE TE +T A++ +T T+ +G Sbjct: 860 ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 915 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 TT T S E+ + S SE+ E Sbjct: 916 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 950 Score = 52.8 bits (125), Expect = 2e-06 Identities = 61/250 (24%), Positives = 96/250 (38%), Gaps = 16/250 (6%) Query: 846 SSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFG--EESTPGQTNSETAVV 903 SS T AP T E + + T+AS E +TP T S+T +V Sbjct: 20 SSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIV 79 Query: 904 ALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT-----SEETVG 958 +++ + + +T G+ T+S A G SE + A + TT +E T+ Sbjct: 80 SISGSEITTTSTAGSE-NTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMV 138 Query: 959 GAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTEL 1018 A+ +TT+ T T + A T T T D T+ + G+E+ Sbjct: 139 SAMGSETTTNSTTSSET---TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 195 Query: 1019 IQTPLASSTDHQTPPTSPVQGTTPQISPS-TLIGSLRTLELGSESQGASESQAP---GEE 1074 T + ++ TP T+ + TT + S T S E + S SE+ A G E Sbjct: 196 -TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSE 254 Query: 1075 NLLGEAAGGQ 1084 AG + Sbjct: 255 TTKVSTAGSE 264 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 628 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 686 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++ TTS E Sbjct: 687 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 743 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 744 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 802 Query: 1062 SQGAS 1066 + AS Sbjct: 803 TTMAS 807 Score = 52.0 bits (123), Expect = 3e-06 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET T + SE T T ++T + Sbjct: 700 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 756 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 757 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 816 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 817 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 874 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 875 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 933 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 349 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 408 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 409 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 467 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 468 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 527 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 528 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 587 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 588 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 646 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 647 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 706 Query: 1077 LGEAAG 1082 E +G Sbjct: 707 STEGSG 712 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 980 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1035 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1036 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1094 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1095 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1154 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1155 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1210 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1211 GSETTTASTAGSE 1223 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 161 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 220 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 221 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 276 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 277 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 336 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 337 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 388 Score = 47.8 bits (112), Expect = 6e-05 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 658 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 717 Query: 941 EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000 T +TT T G + TT+ T T E +T T+ A+ E Sbjct: 718 -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 769 Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 G+ + T SE T +T +AS +T S + T ++S ++ Sbjct: 770 GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 820 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 896 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 955 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 956 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 1015 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 1016 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1075 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1076 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1119 Score = 47.8 bits (112), Expect = 6e-05 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1057 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1115 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T G A TTS + +T G SE T++ Sbjct: 1116 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1172 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049 +TT S E T SE TE +T AS+ +T S T S S Sbjct: 1173 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1230 Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075 GS + S+ ++ S A E N Sbjct: 1231 -GSETNTACTTGSETSTPSSAGSETN 1255 Score = 46.6 bits (109), Expect = 1e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 567 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 626 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 627 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 686 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 687 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 743 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 744 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 782 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 309 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 368 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 369 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 422 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 423 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 481 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 482 SETTTVTTAGSETKTAYTTGSETTTASNT 510 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 880 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 939 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 940 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 995 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 996 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1049 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1050 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1098 Score = 44.3 bits (103), Expect = 7e-04 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914 TT + + + MG T+ ++ G E+T T NSET + + T + + + Sbjct: 788 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 847 Query: 915 TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974 T G+ +TI A+ G+ TTS E T SE T +TT+ +G Sbjct: 848 TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 903 Query: 975 TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021 T TT+ +T T+ + EG+ T+ T SE TE +T Sbjct: 904 T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 954 Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079 AS+ + S T +S GS T +GSE+ AS + G E Sbjct: 955 TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 1008 Query: 1080 AAGGQDMADSMLMQGSRGLT 1099 AG + S ++GS T Sbjct: 1009 TAGSETTTAS--IEGSETTT 1026 Score = 41.6 bits (96), Expect = 0.005 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 601 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 653 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 654 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 710 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 711 SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 764 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 765 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 799 Score = 39.7 bits (91), Expect = 0.018 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%) Query: 874 VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919 V +G G T+++ G E+T SE V+ T + + A+T G+ T Sbjct: 1107 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1166 Query: 920 LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973 + T+SE + + T+ A G +TT+ T G + TT+ A Sbjct: 1167 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1223 Query: 974 ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030 T T+ E T TS + G+ + SE T ++ S T + Sbjct: 1224 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1283 Query: 1031 TPPTS 1035 T S Sbjct: 1284 TTTVS 1288 >gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] Length = 520 Score = 55.1 bits (131), Expect = 4e-07 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 22/100 (22%) Query: 1113 CPHLVA-VCPIPAA-----GLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHG 1166 CPHL + VC P + G + C C + + WVCL+C V+CGRY+NGH +H+ Sbjct: 3 CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYE 62 Query: 1167 NSGHPLV----------------LSYIDLSAWCYYCQAYV 1190 ++ PL + S +CY C +V Sbjct: 63 DAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFV 102 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G E+T SET V++T + + + G+ T + T SE + Sbjct: 78 VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 138 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Score = 53.5 bits (127), Expect = 1e-06 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%) Query: 881 KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935 ++T+AS G E+T T SET + + + A+T G+ T + T SE + M Sbjct: 721 EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780 Query: 936 QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983 +TT +G T +T SE T+ +TT+ G T+ +T+ Sbjct: 781 ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838 Query: 984 AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039 G+ TTS E T SE TE +T A++ +T T+ +G Sbjct: 839 ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 TT T S E+ + S SE+ E Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 +++A S + E +TP T S+T +V+++ + + +T G+ T+S A G Sbjct: 29 LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991 TT+ G T T ET +I +TT A+G T TTS E +T Sbjct: 85 ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 992 QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045 T+ + G+ T D T+ + G+E+ T + ++ TP T+ + TT + Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200 Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084 S T S E + S SE+ A G E AG + Sbjct: 201 GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++ TTS E Sbjct: 666 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781 Query: 1062 SQGAS 1066 + AS Sbjct: 782 TTMAS 786 Score = 52.0 bits (123), Expect = 3e-06 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET T + SE T T ++T + Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 736 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 796 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912 Score = 51.2 bits (121), Expect = 6e-06 Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 20/244 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V +G G T+++ G SET V +T + + A+T G+ A T+S + Sbjct: 1086 VSTSGSGTTTASTAG---------SETTTVYITGSKTTTASTEGSE-ATTVSTTSSETTT 1135 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ- 992 T SE T +TT+ T+G + TTS A AT T E +T Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGS---EATTSSAAGSEATTTSTEGSETTTASTAGSE 1192 Query: 993 --TTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLI 1050 T S A E T SE T +T A +T +T S T + + +I Sbjct: 1193 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET---NTAFII 1249 Query: 1051 GSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPL 1110 GS T+ + + + S E + A G A + + + LT +A ++ P+ Sbjct: 1250 GSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLT-KATDVSIQPI 1308 Query: 1111 PWCP 1114 P Sbjct: 1309 TNTP 1312 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 447 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 626 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685 Query: 1077 LGEAAG 1082 E +G Sbjct: 686 STEGSG 691 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 959 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1190 GSETTTASTAGSE 1202 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 140 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 200 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367 Score = 48.5 bits (114), Expect = 4e-05 Identities = 58/213 (27%), Positives = 80/213 (37%), Gaps = 15/213 (7%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQ------TTSEEAV 985 SE T +TT+ T G A TTS + +T G TT E Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154 Query: 986 GGATL---AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTP 1042 +T+ A T+S A E T SE T +T AS+ +T S T Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETT 1214 Query: 1043 QISPSTLIGSLRTLELGSESQGASESQAPGEEN 1075 S S GS + S+ ++ S A E N Sbjct: 1215 TASTS---GSETNTACTTGSETSTPSSAGSETN 1244 Score = 47.8 bits (112), Expect = 6e-05 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 637 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 941 EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000 T +TT T G + TT+ T T E +T T+ A+ E Sbjct: 697 -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748 Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 G+ + T SE T +T +AS +T S + T ++S ++ Sbjct: 749 GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 875 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 935 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Score = 46.6 bits (109), Expect = 1e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 723 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 288 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 348 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNT 489 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 859 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 919 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 975 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077 Score = 44.3 bits (103), Expect = 7e-04 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914 TT + + + MG T+ ++ G E+T T NSET + + T + + + Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826 Query: 915 TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974 T G+ +TI A+ G+ TTS E T SE T +TT+ +G Sbjct: 827 TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882 Query: 975 TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021 T TT+ +T T+ + EG+ T+ T SE TE +T Sbjct: 883 T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079 AS+ + S T +S GS T +GSE+ AS + G E Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987 Query: 1080 AAGGQDMADSMLMQGSRGLT 1099 AG + S ++GS T Sbjct: 988 TAGSETTTAS--IEGSETTT 1005 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%) Query: 882 VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929 V A+ +T T SET + + + + A+T G+ T + T S+ I Sbjct: 7 VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 930 --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985 A TT A G T ET +TT+ G T + SE Sbjct: 67 TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126 Query: 986 GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043 T ++T TS A E T+ SE T +T AS+T + T+ + Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184 Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091 I+PST T+ GSE+ S + G E A + A S + Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230 Score = 41.6 bits (96), Expect = 0.005 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 580 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 633 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778 >gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G E+T SET V++T + + + G+ T + T SE + Sbjct: 78 VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 138 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Score = 53.5 bits (127), Expect = 1e-06 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%) Query: 881 KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935 ++T+AS G E+T T SET + + + A+T G+ T + T SE + M Sbjct: 721 EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780 Query: 936 QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983 +TT +G T +T SE T+ +TT+ G T+ +T+ Sbjct: 781 ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838 Query: 984 AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039 G+ TTS E T SE TE +T A++ +T T+ +G Sbjct: 839 ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 TT T S E+ + S SE+ E Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 +++A S + E +TP T S+T +V+++ + + +T G+ T+S A G Sbjct: 29 LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991 TT+ G T T ET +I +TT A+G T TTS E +T Sbjct: 85 ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 992 QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045 T+ + G+ T D T+ + G+E+ T + ++ TP T+ + TT + Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200 Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084 S T S E + S SE+ A G E AG + Sbjct: 201 GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++ TTS E Sbjct: 666 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781 Query: 1062 SQGAS 1066 + AS Sbjct: 782 TTMAS 786 Score = 52.0 bits (123), Expect = 3e-06 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET T + SE T T ++T + Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 736 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 796 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 447 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 626 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685 Query: 1077 LGEAAG 1082 E +G Sbjct: 686 STEGSG 691 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 959 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1190 GSETTTASTAGSE 1202 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 140 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 200 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367 Score = 47.8 bits (112), Expect = 6e-05 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 637 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 941 EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000 T +TT T G + TT+ T T E +T T+ A+ E Sbjct: 697 -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748 Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 G+ + T SE T +T +AS +T S + T ++S ++ Sbjct: 749 GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 875 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 935 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Score = 47.8 bits (112), Expect = 6e-05 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T G A TTS + +T G SE T++ Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049 +TT S E T SE TE +T AS+ +T S T S S Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209 Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075 GS + S+ ++ S A E N Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234 Score = 46.6 bits (109), Expect = 1e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 723 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 288 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 348 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNT 489 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 859 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 919 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 975 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077 Score = 44.3 bits (103), Expect = 7e-04 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914 TT + + + MG T+ ++ G E+T T NSET + + T + + + Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826 Query: 915 TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974 T G+ +TI A+ G+ TTS E T SE T +TT+ +G Sbjct: 827 TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882 Query: 975 TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021 T TT+ +T T+ + EG+ T+ T SE TE +T Sbjct: 883 T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079 AS+ + S T +S GS T +GSE+ AS + G E Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987 Query: 1080 AAGGQDMADSMLMQGSRGLT 1099 AG + S ++GS T Sbjct: 988 TAGSETTTAS--IEGSETTT 1005 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%) Query: 882 VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929 V A+ +T T SET + + + + A+T G+ T + T S+ I Sbjct: 7 VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 930 --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985 A TT A G T ET +TT+ G T + SE Sbjct: 67 TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126 Query: 986 GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043 T ++T TS A E T+ SE T +T AS+T + T+ + Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184 Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091 I+PST T+ GSE+ S + G E A + A S + Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230 Score = 41.6 bits (96), Expect = 0.005 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 580 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 633 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778 Score = 39.7 bits (91), Expect = 0.018 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%) Query: 874 VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919 V +G G T+++ G E+T SE V+ T + + A+T G+ T Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145 Query: 920 LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973 + T+SE + + T+ A G +TT+ T G + TT+ A Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202 Query: 974 ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030 T T+ E T TS + G+ + SE T ++ S T + Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262 Query: 1031 TPPTS 1035 T S Sbjct: 1263 TTTVS 1267 >gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G E+T SET V++T + + + G+ T + T SE + Sbjct: 78 VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 138 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Score = 53.5 bits (127), Expect = 1e-06 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%) Query: 881 KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935 ++T+AS G E+T T SET + + + A+T G+ T + T SE + M Sbjct: 721 EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780 Query: 936 QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983 +TT +G T +T SE T+ +TT+ G T+ +T+ Sbjct: 781 ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838 Query: 984 AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039 G+ TTS E T SE TE +T A++ +T T+ +G Sbjct: 839 ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 TT T S E+ + S SE+ E Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 +++A S + E +TP T S+T +V+++ + + +T G+ T+S A G Sbjct: 29 LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991 TT+ G T T ET +I +TT A+G T TTS E +T Sbjct: 85 ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 992 QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045 T+ + G+ T D T+ + G+E+ T + ++ TP T+ + TT + Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200 Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084 S T S E + S SE+ A G E AG + Sbjct: 201 GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++ TTS E Sbjct: 666 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781 Query: 1062 SQGAS 1066 + AS Sbjct: 782 TTMAS 786 Score = 52.0 bits (123), Expect = 3e-06 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET T + SE T T ++T + Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 736 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 796 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 447 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 626 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685 Query: 1077 LGEAAG 1082 E +G Sbjct: 686 STEGSG 691 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 959 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1190 GSETTTASTAGSE 1202 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 140 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 200 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367 Score = 47.8 bits (112), Expect = 6e-05 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 637 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 941 EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000 T +TT T G + TT+ T T E +T T+ A+ E Sbjct: 697 -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748 Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 G+ + T SE T +T +AS +T S + T ++S ++ Sbjct: 749 GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 875 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 935 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Score = 47.8 bits (112), Expect = 6e-05 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T G A TTS + +T G SE T++ Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049 +TT S E T SE TE +T AS+ +T S T S S Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209 Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075 GS + S+ ++ S A E N Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234 Score = 46.6 bits (109), Expect = 1e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 723 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 288 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 348 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNT 489 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 859 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 919 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 975 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077 Score = 44.3 bits (103), Expect = 7e-04 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914 TT + + + MG T+ ++ G E+T T NSET + + T + + + Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826 Query: 915 TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974 T G+ +TI A+ G+ TTS E T SE T +TT+ +G Sbjct: 827 TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882 Query: 975 TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021 T TT+ +T T+ + EG+ T+ T SE TE +T Sbjct: 883 T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079 AS+ + S T +S GS T +GSE+ AS + G E Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987 Query: 1080 AAGGQDMADSMLMQGSRGLT 1099 AG + S ++GS T Sbjct: 988 TAGSETTTAS--IEGSETTT 1005 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%) Query: 882 VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929 V A+ +T T SET + + + + A+T G+ T + T S+ I Sbjct: 7 VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 930 --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985 A TT A G T ET +TT+ G T + SE Sbjct: 67 TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126 Query: 986 GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043 T ++T TS A E T+ SE T +T AS+T + T+ + Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184 Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091 I+PST T+ GSE+ S + G E A + A S + Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230 Score = 41.6 bits (96), Expect = 0.005 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 580 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 633 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778 Score = 40.0 bits (92), Expect = 0.014 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%) Query: 874 VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919 V +G G T+++ G E+T SE V+ T + + A+T G+ T Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145 Query: 920 LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973 + T+SE + + T+ A G +TT+ T G + TT+ A Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202 Query: 974 ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030 T T+ E T TS + G+ + SE T ++ S T + Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSE 1262 Query: 1031 TPPTS 1035 T S Sbjct: 1263 TTTVS 1267 >gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo sapiens] Length = 1521 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G E+T SET V++T + + + G+ T + T SE + Sbjct: 78 VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 138 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Score = 54.3 bits (129), Expect = 7e-07 Identities = 57/228 (25%), Positives = 88/228 (38%), Gaps = 27/228 (11%) Query: 868 TTREKKVLEAGMGKVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQ 922 T E + ++T+AS G E+T T SET + + + A+T G+ T + Sbjct: 708 TGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAST 767 Query: 923 TISEAAIGGAMLGQTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDA 970 T SE + M +TT +G T +T SE T+ +TT+ Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827 Query: 971 VGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQ 1030 G T+ +T+ G+ TTS E T SE TE +T A++ + Sbjct: 828 AGSETIPASTA-----GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882 Query: 1031 TPPTSPVQG----TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 T T+ +G TT T S E+ + S SE+ E Sbjct: 883 T-TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 53.1 bits (126), Expect = 2e-06 Identities = 58/240 (24%), Positives = 92/240 (38%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET + T + SE T T ++T + Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTI---TSTEGSEITTASITGSETTTA 735 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 736 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 796 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 +++A S + E +TP T S+T +V+++ + + +T G+ T+S A G Sbjct: 29 LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991 TT+ G T T ET +I +TT A+G T TTS E +T Sbjct: 85 ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 992 QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045 T+ + G+ T D T+ + G+E+ T + ++ TP T+ + TT + Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200 Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084 S T S E + S SE+ A G E AG + Sbjct: 201 GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQT--TSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++T TS E Sbjct: 666 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEI 722 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781 Query: 1062 SQGAS 1066 + AS Sbjct: 782 TTMAS 786 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 447 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 626 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685 Query: 1077 LGEAAG 1082 E +G Sbjct: 686 STEGSG 691 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 959 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1190 GSETTTASTAGSE 1202 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 140 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 200 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 875 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 935 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Score = 47.8 bits (112), Expect = 6e-05 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T G A TTS + +T G SE T++ Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049 +TT S E T SE TE +T AS+ +T S T S S Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209 Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075 GS + S+ ++ S A E N Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234 Score = 46.6 bits (109), Expect = 1e-04 Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 12/170 (7%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 637 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 941 EAVGGATPDQTTSEETVGG--AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAA 998 T +TT T G I SE T +TT+ G T T S Sbjct: 697 -----ITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSET--TTASTEG 749 Query: 999 MEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 E + T SE T +T +AS +T S + T ++S ++ Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799 Score = 45.8 bits (107), Expect = 2e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITS-TEGS--EI 722 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 723 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 288 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 348 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNT 489 Score = 45.1 bits (105), Expect = 4e-04 Identities = 50/226 (22%), Positives = 80/226 (35%), Gaps = 19/226 (8%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTIS 925 TT + + + MG T+ ++ G E+T T S T++ + A+ A+ T+S Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826 Query: 926 EAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAV 985 A G T + G+ TTS E SE +TT+ + Sbjct: 827 TA-------GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI 879 Query: 986 GGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT---- 1041 G T T S E T SE TE + S+T +T S T Sbjct: 880 GSET--TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937 Query: 1042 ---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 +++ + GS T+ + +E + G E AG + Sbjct: 938 TEGSELTTVSTTGS-ETITVSAEGSETTTVTTMGSETTTASTAGSE 982 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 859 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 919 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 975 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%) Query: 882 VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929 V A+ +T T SET + + + + A+T G+ T + T S+ I Sbjct: 7 VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 930 --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985 A TT A G T ET +TT+ G T + SE Sbjct: 67 TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126 Query: 986 GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043 T ++T TS A E T+ SE T +T AS+T + T+ + Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184 Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091 I+PST T+ GSE+ S + G E A + A S + Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230 Score = 40.8 bits (94), Expect = 0.008 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 580 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 633 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTIT----STEGSEITTASITGS--ETTTASTEGSETT 743 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778 Score = 39.7 bits (91), Expect = 0.018 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%) Query: 874 VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919 V +G G T+++ G E+T SE V+ T + + A+T G+ T Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145 Query: 920 LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973 + T+SE + + T+ A G +TT+ T G + TT+ A Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202 Query: 974 ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030 T T+ E T TS + G+ + SE T ++ S T + Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262 Query: 1031 TPPTS 1035 T S Sbjct: 1263 TTTVS 1267 >gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G E+T SET V++T + + + G+ T + T SE + Sbjct: 78 VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 138 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Score = 53.5 bits (127), Expect = 1e-06 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%) Query: 881 KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935 ++T+AS G E+T T SET + + + A+T G+ T + T SE + M Sbjct: 721 EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780 Query: 936 QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983 +TT +G T +T SE T+ +TT+ G T+ +T+ Sbjct: 781 ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838 Query: 984 AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039 G+ TTS E T SE TE +T A++ +T T+ +G Sbjct: 839 ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 TT T S E+ + S SE+ E Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 +++A S + E +TP T S+T +V+++ + + +T G+ T+S A G Sbjct: 29 LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991 TT+ G T T ET +I +TT A+G T TTS E +T Sbjct: 85 ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 992 QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045 T+ + G+ T D T+ + G+E+ T + ++ TP T+ + TT + Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200 Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084 S T S E + S SE+ A G E AG + Sbjct: 201 GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++ TTS E Sbjct: 666 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781 Query: 1062 SQGAS 1066 + AS Sbjct: 782 TTMAS 786 Score = 52.0 bits (123), Expect = 3e-06 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET T + SE T T ++T + Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 736 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 796 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 447 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 626 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685 Query: 1077 LGEAAG 1082 E +G Sbjct: 686 STEGSG 691 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 959 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1190 GSETTTASTAGSE 1202 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 140 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 200 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367 Score = 47.8 bits (112), Expect = 6e-05 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 637 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 941 EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000 T +TT T G + TT+ T T E +T T+ A+ E Sbjct: 697 -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748 Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 G+ + T SE T +T +AS +T S + T ++S ++ Sbjct: 749 GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 875 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 935 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Score = 47.8 bits (112), Expect = 6e-05 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T G A TTS + +T G SE T++ Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049 +TT S E T SE TE +T AS+ +T S T S S Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209 Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075 GS + S+ ++ S A E N Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234 Score = 46.6 bits (109), Expect = 1e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 723 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 288 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 348 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNT 489 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 859 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 919 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 975 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077 Score = 44.3 bits (103), Expect = 7e-04 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914 TT + + + MG T+ ++ G E+T T NSET + + T + + + Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826 Query: 915 TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974 T G+ +TI A+ G+ TTS E T SE T +TT+ +G Sbjct: 827 TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882 Query: 975 TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021 T TT+ +T T+ + EG+ T+ T SE TE +T Sbjct: 883 T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079 AS+ + S T +S GS T +GSE+ AS + G E Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987 Query: 1080 AAGGQDMADSMLMQGSRGLT 1099 AG + S ++GS T Sbjct: 988 TAGSETTTAS--IEGSETTT 1005 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%) Query: 882 VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929 V A+ +T T SET + + + + A+T G+ T + T S+ I Sbjct: 7 VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 930 --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985 A TT A G T ET +TT+ G T + SE Sbjct: 67 TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126 Query: 986 GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043 T ++T TS A E T+ SE T +T AS+T + T+ + Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184 Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091 I+PST T+ GSE+ S + G E A + A S + Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230 Score = 41.6 bits (96), Expect = 0.005 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 580 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 633 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778 Score = 39.7 bits (91), Expect = 0.018 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%) Query: 874 VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919 V +G G T+++ G E+T SE V+ T + + A+T G+ T Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145 Query: 920 LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973 + T+SE + + T+ A G +TT+ T G + TT+ A Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202 Query: 974 ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030 T T+ E T TS + G+ + SE T ++ S T + Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262 Query: 1031 TPPTS 1035 T S Sbjct: 1263 TTTVS 1267 >gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] Length = 1704 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G E+T SET V++T + + + G+ T + T SE + Sbjct: 78 VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 138 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Score = 53.5 bits (127), Expect = 1e-06 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%) Query: 881 KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935 ++T+AS G E+T T SET + + + A+T G+ T + T SE + M Sbjct: 721 EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780 Query: 936 QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983 +TT +G T +T SE T+ +TT+ G T+ +T+ Sbjct: 781 ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838 Query: 984 AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039 G+ TTS E T SE TE +T A++ +T T+ +G Sbjct: 839 ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 TT T S E+ + S SE+ E Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 +++A S + E +TP T S+T +V+++ + + +T G+ T+S A G Sbjct: 29 LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991 TT+ G T T ET +I +TT A+G T TTS E +T Sbjct: 85 ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 992 QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045 T+ + G+ T D T+ + G+E+ T + ++ TP T+ + TT + Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200 Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084 S T S E + S SE+ A G E AG + Sbjct: 201 GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++ TTS E Sbjct: 666 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781 Query: 1062 SQGAS 1066 + AS Sbjct: 782 TTMAS 786 Score = 52.0 bits (123), Expect = 3e-06 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET T + SE T T ++T + Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 736 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 796 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 447 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 626 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685 Query: 1077 LGEAAG 1082 E +G Sbjct: 686 STEGSG 691 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 959 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1190 GSETTTASTAGSE 1202 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 140 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 200 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367 Score = 47.8 bits (112), Expect = 6e-05 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 637 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 941 EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000 T +TT T G + TT+ T T E +T T+ A+ E Sbjct: 697 -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748 Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 G+ + T SE T +T +AS +T S + T ++S ++ Sbjct: 749 GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 875 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 935 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Score = 47.8 bits (112), Expect = 6e-05 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T G A TTS + +T G SE T++ Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049 +TT S E T SE TE +T AS+ +T S T S S Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209 Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075 GS + S+ ++ S A E N Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234 Score = 46.6 bits (109), Expect = 1e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 723 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 288 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 348 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNT 489 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 859 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 919 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 975 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077 Score = 44.3 bits (103), Expect = 7e-04 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914 TT + + + MG T+ ++ G E+T T NSET + + T + + + Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826 Query: 915 TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974 T G+ +TI A+ G+ TTS E T SE T +TT+ +G Sbjct: 827 TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882 Query: 975 TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021 T TT+ +T T+ + EG+ T+ T SE TE +T Sbjct: 883 T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079 AS+ + S T +S GS T +GSE+ AS + G E Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987 Query: 1080 AAGGQDMADSMLMQGSRGLT 1099 AG + S ++GS T Sbjct: 988 TAGSETTTAS--IEGSETTT 1005 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%) Query: 882 VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929 V A+ +T T SET + + + + A+T G+ T + T S+ I Sbjct: 7 VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 930 --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985 A TT A G T ET +TT+ G T + SE Sbjct: 67 TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126 Query: 986 GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043 T ++T TS A E T+ SE T +T AS+T + T+ + Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184 Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091 I+PST T+ GSE+ S + G E A + A S + Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230 Score = 41.6 bits (96), Expect = 0.005 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 580 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 633 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778 Score = 39.7 bits (91), Expect = 0.018 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%) Query: 874 VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919 V +G G T+++ G E+T SE V+ T + + A+T G+ T Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145 Query: 920 LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973 + T+SE + + T+ A G +TT+ T G + TT+ A Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202 Query: 974 ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030 T T+ E T TS + G+ + SE T ++ S T + Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262 Query: 1031 TPPTS 1035 T S Sbjct: 1263 TTTVS 1267 >gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 54.7 bits (130), Expect = 5e-07 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930 V AG G T++ G E+T SET V++T + + + G+ T + T SE + Sbjct: 78 VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137 Query: 931 GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990 +TT+ VG T T++ A TT + T G T + G+ Sbjct: 138 STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193 Query: 991 AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041 T S A E T+ T SE T +T AS+ +T S T Sbjct: 194 TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244 Score = 53.5 bits (127), Expect = 1e-06 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%) Query: 881 KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935 ++T+AS G E+T T SET + + + A+T G+ T + T SE + M Sbjct: 721 EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780 Query: 936 QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983 +TT +G T +T SE T+ +TT+ G T+ +T+ Sbjct: 781 ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838 Query: 984 AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039 G+ TTS E T SE TE +T A++ +T T+ +G Sbjct: 839 ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074 TT T S E+ + S SE+ E Sbjct: 895 TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 +++A S + E +TP T S+T +V+++ + + +T G+ T+S A G Sbjct: 29 LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991 TT+ G T T ET +I +TT A+G T TTS E +T Sbjct: 85 ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141 Query: 992 QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045 T+ + G+ T D T+ + G+E+ T + ++ TP T+ + TT + Sbjct: 142 SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200 Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084 S T S E + S SE+ A G E AG + Sbjct: 201 GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243 Score = 52.4 bits (124), Expect = 3e-06 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943 S + E ++ T SET + T + + A+T G+ T+S M+ T SE + Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665 Query: 944 GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001 +TT+ G + T S + G T+ T SE T ++ TTS E Sbjct: 666 TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722 Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061 T T SE TE +T AS+ +T S T S ++ ++ ++ +GSE Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781 Query: 1062 SQGAS 1066 + AS Sbjct: 782 TTMAS 786 Score = 52.0 bits (123), Expect = 3e-06 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%) Query: 868 TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926 T E V G G T + G E+T T SET T + SE T T ++T + Sbjct: 679 TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735 Query: 927 AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978 + G +T SE T +TT SE T+ + +TT +G T Sbjct: 736 STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795 Query: 979 TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032 +T+ + T+ SE + T +TT SE P T +T +ST+ Sbjct: 796 STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853 Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 T+ +G+ + + + +T IGS T +E + + G E G + Sbjct: 854 TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912 Score = 51.2 bits (121), Expect = 6e-06 Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 20/244 (8%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V +G G T+++ G SET V +T + + A+T G+ A T+S + Sbjct: 1086 VSTSGSGTTTASTAG---------SETTTVYITGSKTTTASTEGSE-ATTVSTTSSETTT 1135 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ- 992 T SE T +TT+ T+G + TTS A AT T E +T Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGS---EATTSSAAGSEATTTSTEGSETTTASTAGSE 1192 Query: 993 --TTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLI 1050 T S A E T SE T +T A +T +T S T + + +I Sbjct: 1193 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET---NTAFII 1249 Query: 1051 GSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPL 1110 GS T+ + + + S E + A G A + + + LT +A ++ P+ Sbjct: 1250 GSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLT-KATDVSIQPI 1308 Query: 1111 PWCP 1114 P Sbjct: 1309 TNTP 1312 Score = 50.4 bits (119), Expect = 1e-05 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%) Query: 738 SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787 +AG + R +G VS G T +MG S EG T+ Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387 Query: 788 SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844 +E A T S G +++ + +E V + + E E Sbjct: 388 TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446 Query: 845 PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904 +S T + + ++ + K G T+++ G E+T T A Sbjct: 447 STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506 Query: 905 LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963 T+ + A + + T+S + T SE T +TT+ T G + Sbjct: 507 STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566 Query: 964 QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023 TT + +T G T+ + G+ T S A E T SE T +T Sbjct: 567 STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625 Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076 AS+T +T T+ V T + + + GS RT+ S+ + S E + Sbjct: 626 ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685 Query: 1077 LGEAAG 1082 E +G Sbjct: 686 STEGSG 691 Score = 48.9 bits (115), Expect = 3e-05 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901 EG ++ + T + TT V AG T++ G E+T T SET Sbjct: 959 EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014 Query: 902 VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959 V+ T + + +T G+ T++ A + T SE +TT+ T G Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073 Query: 960 -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011 A L+ TT + G T T E T+ A+ EG+ T+ T+SE Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133 Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071 T + +T +T S + G+ S + + T GSE+ AS + Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189 Query: 1072 GEENLLGEAAGGQ 1084 G E AG + Sbjct: 1190 GSETTTASTAGSE 1202 Score = 48.5 bits (114), Expect = 4e-05 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%) Query: 877 AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926 AG T ++ G E+T T +SET + T + + T G+ T+S Sbjct: 140 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199 Query: 927 AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986 A + T SE +TT+ T+G +TT G T T E Sbjct: 200 AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255 Query: 987 GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036 +T T+ A E + T T E T + +AS+ +T P T+ Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315 Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 V + +++ GS +R +GSE+ S + G E G + DS Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367 Score = 48.5 bits (114), Expect = 4e-05 Identities = 58/213 (27%), Positives = 80/213 (37%), Gaps = 15/213 (7%) Query: 874 VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932 V AG + G E+T T SET V+ T + + A+T T+S + G Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094 Query: 933 MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQ------TTSEEAV 985 SE T +TT+ T G A TTS + +T G TT E Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154 Query: 986 GGATL---AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTP 1042 +T+ A T+S A E T SE T +T AS+ +T S T Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETT 1214 Query: 1043 QISPSTLIGSLRTLELGSESQGASESQAPGEEN 1075 S S GS + S+ ++ S A E N Sbjct: 1215 TASTS---GSETNTACTTGSETSTPSSAGSETN 1244 Score = 47.8 bits (112), Expect = 6e-05 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%) Query: 884 SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940 S E +T T+SET +V+ T + + +T G+ T++ T SE + G TT Sbjct: 637 STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696 Query: 941 EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000 T +TT T G + TT+ T T E +T T+ A+ E Sbjct: 697 -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748 Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048 G+ + T SE T +T +AS +T S + T ++S ++ Sbjct: 749 GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799 Score = 47.8 bits (112), Expect = 6e-05 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%) Query: 883 TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938 T+ + G E+T T SET + + + A+T G+ T++ T SE +TT Sbjct: 875 TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934 Query: 939 SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995 + G T TT ET+ A +TT+ +G T T E +T T+ Sbjct: 935 TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994 Query: 996 EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045 A++EG+ T+ T SE T +T + S+ +T T+ V T + + Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054 Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089 ++ GS T + S+ + S A E + + G A + Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098 Score = 46.6 bits (109), Expect = 1e-04 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%) Query: 874 VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933 V G+ T+++ G E T T T+ + AA+ + T+S A Sbjct: 546 VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605 Query: 934 LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991 SE T +TT+ T +T SE T +TT G Sbjct: 606 ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665 Query: 992 QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044 +T SE AT +TT GT + +T S+T +T TS +G+ +I Sbjct: 666 TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722 Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084 + +++ GS T +E + + G E G + Sbjct: 723 TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761 Score = 45.1 bits (105), Expect = 4e-04 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921 TT + + + MG T+ ++ G E+T T +SE V + A+T G+ T++ Sbjct: 288 TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347 Query: 922 QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981 T SE M +T+++ G +TT+ T G T S + T+ T S Sbjct: 348 TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401 Query: 982 EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039 E T ++TT+ E + T E TE + +AS++D +T T+ +G Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460 Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068 + + + GSE+ AS + Sbjct: 461 SETTTVTTAGSETKTAYTTGSETTTASNT 489 Score = 44.7 bits (104), Expect = 5e-04 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%) Query: 843 EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895 EG ++ T+ + + TT + E G T+++ G E +T Sbjct: 859 EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918 Query: 896 TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952 T SET + + + A+T G+ T++ T SE A +TT+ +G +TT Sbjct: 919 TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974 Query: 953 SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012 + T G +TT+ G T T S E T++ T SE T +TT Sbjct: 975 TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028 Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066 G T S T S T+ + S +T + + GSE+ AS Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077 Score = 44.3 bits (103), Expect = 7e-04 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%) Query: 868 TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914 TT + + + MG T+ ++ G E+T T NSET + + T + + + Sbjct: 767 TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826 Query: 915 TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974 T G+ +TI A+ G+ TTS E T SE T +TT+ +G Sbjct: 827 TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882 Query: 975 TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021 T TT+ +T T+ + EG+ T+ T SE TE +T Sbjct: 883 T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079 AS+ + S T +S GS T +GSE+ AS + G E Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987 Query: 1080 AAGGQDMADSMLMQGSRGLT 1099 AG + S ++GS T Sbjct: 988 TAGSETTTAS--IEGSETTT 1005 Score = 41.6 bits (96), Expect = 0.005 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%) Query: 882 VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929 V A+ +T T SET + + + + A+T G+ T + T S+ I Sbjct: 7 VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66 Query: 930 --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985 A TT A G T ET +TT+ G T + SE Sbjct: 67 TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126 Query: 986 GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043 T ++T TS A E T+ SE T +T AS+T + T+ + Sbjct: 127 NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184 Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091 I+PST T+ GSE+ S + G E A + A S + Sbjct: 185 ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230 Score = 41.6 bits (96), Expect = 0.005 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%) Query: 878 GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936 G G +++ G E+T T +SE + + + A+T G SE + Sbjct: 580 GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632 Query: 937 TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995 TT+ G T TT ET ++ T SE + +TT+ A G T T Sbjct: 633 TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689 Query: 996 EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055 + T++ + G+E T ST+ T+ + G+ + + ++ GS T Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743 Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090 S+ S S E + MA M Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 50,672,043 Number of Sequences: 37866 Number of extensions: 2465847 Number of successful extensions: 10817 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 160 Number of HSP's that attempted gapping in prelim test: 8751 Number of HSP's gapped (non-prelim): 1105 length of query: 1215 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1101 effective length of database: 13,930,794 effective search space: 15337804194 effective search space used: 15337804194 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.