Search of human proteins with 13128864

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13128864 histone deacetylase 6 [Homo sapiens]
         (1215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13128864 histone deacetylase 6 [Homo sapiens]                     2469   0.0  
gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]           407   e-113
gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]          368   e-101
gi|153085395 histone deacetylase 4 [Homo sapiens]                     301   2e-81
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]            286   8e-77
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]            286   8e-77
gi|148539870 histone deacetylase 7 isoform d [Homo sapiens]           285   1e-76
gi|169234807 histone deacetylase 7 isoform a [Homo sapiens]           285   1e-76
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]            282   1e-75
gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]            282   1e-75
gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens]            268   2e-71
gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens]            155   3e-37
gi|8923769 histone deacetylase 8 [Homo sapiens]                       107   7e-23
gi|116284376 histone deacetylase 2 [Homo sapiens]                     103   1e-21
gi|13128860 histone deacetylase 1 [Homo sapiens]                      102   3e-21
gi|13128862 histone deacetylase 3 [Homo sapiens]                       83   1e-15
gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens]           81   7e-15
gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens]           76   2e-13
gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]                   69   4e-11
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]                 67   8e-11
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]                 67   8e-11
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            55   3e-07
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]                   55   4e-07
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            55   5e-07
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            55   5e-07
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            55   5e-07
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    55   5e-07
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            55   5e-07
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            55   5e-07
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            55   5e-07

>gi|13128864 histone deacetylase 6 [Homo sapiens]
          Length = 1215

 Score = 2469 bits (6398), Expect = 0.0
 Identities = 1215/1215 (100%), Positives = 1215/1215 (100%)

Query: 1    MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG 60
            MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG
Sbjct: 1    MTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPRSIPNLAEVKKKGKMKKLG 60

Query: 61   QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI 120
            QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI
Sbjct: 61   QAMEEDLIVGLQGMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLI 120

Query: 121  QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS 180
            QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS
Sbjct: 121  QEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNS 180

Query: 181  YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ 240
            YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ
Sbjct: 181  YSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQ 240

Query: 241  KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG 300
            KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
Sbjct: 241  KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG 300

Query: 301  QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP 360
            QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
Sbjct: 301  QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP 360

Query: 361  AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA 420
            AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
Sbjct: 361  AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA 420

Query: 421  QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR 480
            QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
Sbjct: 421  QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR 480

Query: 481  TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH 540
            TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH
Sbjct: 481  TGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCH 540

Query: 541  SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN 600
            SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN
Sbjct: 541  SAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLN 600

Query: 601  GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660
            GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF
Sbjct: 601  GAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660

Query: 661  EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH 720
            EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH
Sbjct: 661  EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH 720

Query: 721  RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG 780
            RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG
Sbjct: 721  RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG 780

Query: 781  GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE 840
            GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE
Sbjct: 781  GYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVE 840

Query: 841  DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET 900
            DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET
Sbjct: 841  DREGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSET 900

Query: 901  AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA 960
            AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA
Sbjct: 901  AVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGA 960

Query: 961  ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ 1020
            ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ
Sbjct: 961  ILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQ 1020

Query: 1021 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA 1080
            TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA
Sbjct: 1021 TPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEA 1080

Query: 1081 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ 1140
            AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ
Sbjct: 1081 AGGQDMADSMLMQGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQ 1140

Query: 1141 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN 1200
            ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN
Sbjct: 1141 ENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHHQALLDVKN 1200

Query: 1201 IAHQNKFGEDMPHPH 1215
            IAHQNKFGEDMPHPH
Sbjct: 1201 IAHQNKFGEDMPHPH 1215


>gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]
          Length = 669

 Score =  407 bits (1046), Expect = e-113
 Identities = 203/388 (52%), Positives = 267/388 (68%), Gaps = 8/388 (2%)

Query: 85  GTGLVLDEQLNEFHCLWDDSFPE--GPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELM 142
           GT LV  E +     LWDD   E   PERL A  ++L Q GL  RC+   AR A +EEL 
Sbjct: 2   GTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELG 61

Query: 143 LVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAE 202
           LVHS EY+ L+  TQ + + EL+ L+  +D++Y HP+++ CA LA+G+ L+LVDAVL   
Sbjct: 62  LVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGA 121

Query: 203 IRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQF 262
           ++NG+A++RPPGHH Q +  +G+C+FN+VA+AA +A+QKH + R+L+VDWDVHHGQG Q+
Sbjct: 122 VQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQY 181

Query: 263 TFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAA 322
            F+ DPSVLYFS HRYE GRFWP L+ S+    G GQG G+T+N+PWNQVGM +ADY+AA
Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241

Query: 323 FLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSL 382
           FLH+LLP+A EF P+LVLV+AGFD+  GDP+G+M ATP  FA LT LL  LAGG++   L
Sbjct: 242 FLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVL 301

Query: 383 EGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRST 442
           EGGY+L +LAE V  ++ TLLGDP P L  P APC+SA  S+  A  A  P W+ L +  
Sbjct: 302 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 361

Query: 443 ETVERDNMEEDNVEESEEEGPWEPPVLP 470
            T     +       S E  P  PP+LP
Sbjct: 362 VTA----VPMSPSSHSPEGRP--PPLLP 383



 Score =  361 bits (926), Expect = 3e-99
 Identities = 188/361 (52%), Positives = 241/361 (66%), Gaps = 3/361 (0%)

Query: 481 TGLVYDQNMMNHCNLWDSHHPEV--PQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
           T LVY ++M     LWD    E+  P+R+   + RL + GL  RCL L+ R A+E EL  
Sbjct: 3   TALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGL 62

Query: 539 CHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEV 598
            HS EYV  +R T+ +   EL   S  FD+IY  PSTF CA+LA GA  +LV+AVL+G V
Sbjct: 63  VHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAV 122

Query: 599 LNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQH 658
            NG A+VRPPGHH ++ AA GFC FN+VA+AA HA+   G   RIL+VDWDVHHG G Q+
Sbjct: 123 QNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHG-LHRILVVDWDVHHGQGIQY 181

Query: 659 MFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAA 718
           +FEDDPSVLY S HRY+HG F+P   E  +  +GR  G GFTVN+ WN   MG+ADY+AA
Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241

Query: 719 WHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILIL 778
           +  L+LP+A+EF+PELVLVSAGFD+A GDP G  Q +PE +AHLT LL  LA GR+  +L
Sbjct: 242 FLHLLLPLAFEFDPELVLVSAGFDSAIGDPEGQMQATPECFAHLTQLLQVLAGGRVCAVL 301

Query: 779 EGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838
           EGGY+L S++ES+    ++LLGDP P L+ P  P   AL SI         +W+SL+   
Sbjct: 302 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 361

Query: 839 V 839
           V
Sbjct: 362 V 362



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 13/85 (15%)

Query: 722 LVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGG 781
           LVLP+AY F P+LVLV+ G       P  G Q  P   A L  +L GLA GR++ +LE  
Sbjct: 562 LVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRGLAGGRVLALLEE- 611

Query: 782 YNLTSISESMAACTRSLLGDPPPLL 806
               S  +      R L G+ PP L
Sbjct: 612 ---NSTPQLAGILARVLNGEAPPSL 633



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 15/121 (12%)

Query: 319 YIAAFLHVLLPVALEFQPQLVLVAAG-FDALQGDPKGEMAATPAGFAQLTHLLMGLAGGK 377
           +++  L ++LP+A  FQP LVLVA G    LQG     +AA          +L GLAGG+
Sbjct: 555 FLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAA----------MLRGLAGGR 604

Query: 378 LILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEV 437
           ++  LE   N      G+ A    L G+  P L            ++      LEP W++
Sbjct: 605 VLALLE--ENSTPQLAGILA--RVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM 660

Query: 438 L 438
           L
Sbjct: 661 L 661


>gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]
          Length = 649

 Score =  368 bits (944), Expect = e-101
 Identities = 190/388 (48%), Positives = 250/388 (64%), Gaps = 28/388 (7%)

Query: 85  GTGLVLDEQLNEFHCLWDDSFPE--GPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELM 142
           GT LV  E +     LWDD   E   PERL A  ++L Q GL  RC+   AR A +EEL 
Sbjct: 2   GTALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELG 61

Query: 143 LVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGAE 202
           LVHS EY+ L+  TQ + + EL+ L+  +D++Y HP+++ CA LA+G+ L+LVDAVL   
Sbjct: 62  LVHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGA 121

Query: 203 IRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQF 262
           ++NG+A++RPPGHH Q +  +G+C+FN+VA+AA +A+QKH + R+L+VDWDVHHGQG Q+
Sbjct: 122 VQNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHGLHRILVVDWDVHHGQGIQY 181

Query: 263 TFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAA 322
            F+ DPSVLYFS HRYE GRFWP L+ S+    G GQG G+T+N+PWNQVGM +ADY+AA
Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241

Query: 323 FLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSL 382
           FLH+LLP+A E                    G+M ATP  FA LT LL  LAGG++   L
Sbjct: 242 FLHLLLPLAFE--------------------GQMQATPECFAHLTQLLQVLAGGRVCAVL 281

Query: 383 EGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRST 442
           EGGY+L +LAE V  ++ TLLGDP P L  P APC+SA  S+  A  A  P W+ L +  
Sbjct: 282 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 341

Query: 443 ETVERDNMEEDNVEESEEEGPWEPPVLP 470
            T     +       S E  P  PP+LP
Sbjct: 342 VTA----VPMSPSSHSPEGRP--PPLLP 363



 Score =  318 bits (816), Expect = 2e-86
 Identities = 172/361 (47%), Positives = 223/361 (61%), Gaps = 23/361 (6%)

Query: 481 TGLVYDQNMMNHCNLWDSHHPEV--PQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
           T LVY ++M     LWD    E+  P+R+   + RL + GL  RCL L+ R A+E EL  
Sbjct: 3   TALVYHEDMTATRLLWDDPECEIERPERLTAALDRLRQRGLEQRCLRLSAREASEEELGL 62

Query: 539 CHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEV 598
            HS EYV  +R T+ +   EL   S  FD+IY  PSTF CA+LA GA  +LV+AVL+G V
Sbjct: 63  VHSPEYVSLVRETQVLGKEELQALSGQFDAIYFHPSTFHCARLAAGAGLQLVDAVLTGAV 122

Query: 599 LNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQH 658
            NG A+VRPPGHH ++ AA GFC FN+VA+AA HA+   G   RIL+VDWDVHHG G Q+
Sbjct: 123 QNGLALVRPPGHHGQRAAANGFCVFNNVAIAAAHAKQKHG-LHRILVVDWDVHHGQGIQY 181

Query: 659 MFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAA 718
           +FEDDPSVLY S HRY+HG F+P   E  +  +GR  G GFTVN+ WN   MG+ADY+AA
Sbjct: 182 LFEDDPSVLYFSWHRYEHGRFWPFLRESDADAVGRGQGLGFTVNLPWNQVGMGNADYVAA 241

Query: 719 WHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILIL 778
           +  L+LP+A+E                    G  Q +PE +AHLT LL  LA GR+  +L
Sbjct: 242 FLHLLLPLAFE--------------------GQMQATPECFAHLTQLLQVLAGGRVCAVL 281

Query: 779 EGGYNLTSISESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMK 838
           EGGY+L S++ES+    ++LLGDP P L+ P  P   AL SI         +W+SL+   
Sbjct: 282 EGGYHLESLAESVCMTVQTLLGDPAPPLSGPMAPCQSALESIQSARAAQAPHWKSLQQQD 341

Query: 839 V 839
           V
Sbjct: 342 V 342



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 34/85 (40%), Positives = 43/85 (50%), Gaps = 13/85 (15%)

Query: 722 LVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGG 781
           LVLP+AY F P+LVLV+ G       P  G Q  P   A L  +L GLA GR++ +LE  
Sbjct: 542 LVLPLAYGFQPDLVLVALG-------PGHGLQ-GPHA-ALLAAMLRGLAGGRVLALLEE- 591

Query: 782 YNLTSISESMAACTRSLLGDPPPLL 806
               S  +      R L G+ PP L
Sbjct: 592 ---NSTPQLAGILARVLNGEAPPSL 613



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 15/121 (12%)

Query: 319 YIAAFLHVLLPVALEFQPQLVLVAAG-FDALQGDPKGEMAATPAGFAQLTHLLMGLAGGK 377
           +++  L ++LP+A  FQP LVLVA G    LQG     +AA          +L GLAGG+
Sbjct: 535 FLSCILGLVLPLAYGFQPDLVLVALGPGHGLQGPHAALLAA----------MLRGLAGGR 584

Query: 378 LILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEV 437
           ++  LE   N      G+ A    L G+  P L            ++      LEP W++
Sbjct: 585 VLALLE--ENSTPQLAGILA--RVLNGEAPPSLGPSSVASPEDVQALMYLRGQLEPQWKM 640

Query: 438 L 438
           L
Sbjct: 641 L 641


>gi|153085395 histone deacetylase 4 [Homo sapiens]
          Length = 1084

 Score =  301 bits (772), Expect = 2e-81
 Identities = 182/399 (45%), Positives = 235/399 (58%), Gaps = 39/399 (9%)

Query: 465  EPPVLPILTWPVLQSRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELGLAGR 522
            EPP  P  T       TGLVYD  M+ H C    S  HPE   RI  I  RL+E GL G+
Sbjct: 645  EPPTKPRFT-------TGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGK 697

Query: 523  CLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESS------------------ 564
            C  +  R AT  EL T HS  +   L  T  +  ++L  +                    
Sbjct: 698  CECIRGRKATLEELQTVHSEAHT-LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGV 756

Query: 565  NFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFN 624
            + D+I+    +   A+LA G    LV  V +GE+ NG AVVRPPGHHAE+    GFC+FN
Sbjct: 757  DSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFN 816

Query: 625  SVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGD 684
            SVAVAA+  Q     + +ILIVDWDVHHGNGTQ  F  DPSVLY+SLHRYD G FFP   
Sbjct: 817  SVAVAAKLLQQRLSVS-KILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFP--G 873

Query: 685  EGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGF 741
             GA  ++G   G GF VN+A+ G   P MGDA+YLAA+  +V+PIA EF P++VLVS+GF
Sbjct: 874  SGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGF 933

Query: 742  DAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLL 799
            DA  G   PLGG  +S   + +LT  LMGLA GRI+L LEGG++LT+I ++  AC  +LL
Sbjct: 934  DAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALL 993

Query: 800  G---DPPPLLTLPRPPLSGALASITETIQVHRRYWRSLR 835
            G   DP P   L + P + A+ S+ + +++H +YWR L+
Sbjct: 994  GNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQ 1032



 Score =  251 bits (641), Expect = 3e-66
 Identities = 157/404 (38%), Positives = 219/404 (54%), Gaps = 31/404 (7%)

Query: 86   TGLVLDEQLNEFHCLW--DDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143
            TGLV D  + +  C      S PE   R+ +I  +L + GL  +C   + R A  EEL  
Sbjct: 654  TGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQT 713

Query: 144  VHSLEYIDLMETTQYMNEGELRV------LADTY------------DSVYLHPNSYSCAC 185
            VHS E   L+  T  +N  +L        LA  +            D+++   +S   A 
Sbjct: 714  VHS-EAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAAR 772

Query: 186  LASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIR 245
            LA G V+ LV  V   E++NG A++RPPGHHA+ S   G+C FN VAVAA+  QQ+  + 
Sbjct: 773  LAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVS 832

Query: 246  RVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTI 305
            ++LIVDWDVHHG GTQ  F  DPSVLY S+HRY+ G F+P   A +    G G G G+ +
Sbjct: 833  KILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPD--EVGTGPGVGFNV 890

Query: 306  NVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK--GEMAATP 360
            N+ +       M DA+Y+AAF  V++P+A EF P +VLV++GFDA++G P   G    + 
Sbjct: 891  NMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSA 950

Query: 361  AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLG---DPCPMLESPGAPC 417
              F  LT  LMGLAGG+++L+LEGG++L A+ +   A +  LLG   DP P       P 
Sbjct: 951  RCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPN 1010

Query: 418  RSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEE 461
             +A  S+   +E    +W  L R+T T  R  +E    E  E E
Sbjct: 1011 ANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAE 1054


>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
          Length = 1123

 Score =  286 bits (732), Expect = 8e-77
 Identities = 176/453 (38%), Positives = 249/453 (54%), Gaps = 40/453 (8%)

Query: 408  PMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPP 467
            P LE PGA  +   +     L+ L+ +   L  S  TV    +       +   G   PP
Sbjct: 618  PDLEEPGAGYKKLFSDAQ-PLQPLQVYQAPL--SLATVPHQALGRTQSSPAAPGGMKSPP 674

Query: 468  VLPILTWPVLQSRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELGLAGRCLT 525
              P+         TG+VYD  M+ H C   ++H HPE   RI  I  RL+E GL  +C  
Sbjct: 675  DQPVKHL----FTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCER 730

Query: 526  LTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESS-------------------NF 566
            +  R AT  E+ T HS EY   L  T  +  ++L  +                     + 
Sbjct: 731  IRGRKATLDEIQTVHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDS 789

Query: 567  DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSV 626
            D+++    + +  ++A G    L   V +GE+ NG A++RPPGHHAE+  A GFCFFNSV
Sbjct: 790  DTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSV 849

Query: 627  AVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEG 686
            A+ A+  Q    +  ++LIVDWD+HHGNGTQ  F +DPSVLY+SLHRYD+G FFP    G
Sbjct: 850  AITAKLLQQ-KLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP--GSG 906

Query: 687  ASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDA 743
            A  ++G   G G+ VNVAW G   P +GD +YL A+  +V+PIA+EF+P++VLVSAGFDA
Sbjct: 907  APEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDA 966

Query: 744  ARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG- 800
              G   PLGG  V+   + HLT  LM LA GR++L LEGG++LT+I ++  AC  +LL  
Sbjct: 967  VEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSV 1026

Query: 801  --DPPPLLTLPRPPLSGALASITETIQVHRRYW 831
               P     L + P   A+A++ + I++  ++W
Sbjct: 1027 ELQPLDEAVLQQKPNINAVATLEKVIEIQSKHW 1059



 Score =  235 bits (599), Expect = 2e-61
 Identities = 147/404 (36%), Positives = 213/404 (52%), Gaps = 33/404 (8%)

Query: 86   TGLVLDEQLNEFHCLWDDSF--PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143
            TG+V D  + +  C+  ++   PE   R+ +I  +L + GLL +C   + R A  +E+  
Sbjct: 684  TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQT 743

Query: 144  VHSLEYIDLMETTQYMNEGELRV-------------------LADTYDSVYLHPNSYSCA 184
            VHS EY  L+  T  +N  +L                     +    D+V+   +S S  
Sbjct: 744  VHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV 802

Query: 185  CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244
             +A G +L L   V   E++NG AIIRPPGHHA+ S   G+C FN VA+ A+  QQK  +
Sbjct: 803  RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV 862

Query: 245  RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304
             +VLIVDWD+HHG GTQ  F  DPSVLY S+HRY+ G F+P   A      G G G GY 
Sbjct: 863  GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAP--EEVGGGPGVGYN 920

Query: 305  INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMAAT 359
            +NV W       + D +Y+ AF  V++P+A EF P +VLV+AGFDA++G   P G  + T
Sbjct: 921  VNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVT 980

Query: 360  PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLG---DPCPMLESPGAP 416
               F  LT  LM LAGG+++L+LEGG++L A+ +   A +  LL     P         P
Sbjct: 981  ARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKP 1040

Query: 417  CRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEE 460
              +A A++   +E     W  + +    + R ++ E    E+EE
Sbjct: 1041 NINAVATLEKVIEIQSKHWSCVQKFAAGLGR-SLREAQAGETEE 1083


>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
          Length = 1122

 Score =  286 bits (732), Expect = 8e-77
 Identities = 176/453 (38%), Positives = 249/453 (54%), Gaps = 40/453 (8%)

Query: 408  PMLESPGAPCRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPP 467
            P LE PGA  +   +     L+ L+ +   L  S  TV    +       +   G   PP
Sbjct: 617  PDLEEPGAGYKKLFSDAQ-PLQPLQVYQAPL--SLATVPHQALGRTQSSPAAPGGMKSPP 673

Query: 468  VLPILTWPVLQSRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELGLAGRCLT 525
              P+         TG+VYD  M+ H C   ++H HPE   RI  I  RL+E GL  +C  
Sbjct: 674  DQPVKHL----FTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCER 729

Query: 526  LTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESS-------------------NF 566
            +  R AT  E+ T HS EY   L  T  +  ++L  +                     + 
Sbjct: 730  IRGRKATLDEIQTVHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDS 788

Query: 567  DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSV 626
            D+++    + +  ++A G    L   V +GE+ NG A++RPPGHHAE+  A GFCFFNSV
Sbjct: 789  DTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSV 848

Query: 627  AVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEG 686
            A+ A+  Q    +  ++LIVDWD+HHGNGTQ  F +DPSVLY+SLHRYD+G FFP    G
Sbjct: 849  AITAKLLQQ-KLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFP--GSG 905

Query: 687  ASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDA 743
            A  ++G   G G+ VNVAW G   P +GD +YL A+  +V+PIA+EF+P++VLVSAGFDA
Sbjct: 906  APEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDA 965

Query: 744  ARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG- 800
              G   PLGG  V+   + HLT  LM LA GR++L LEGG++LT+I ++  AC  +LL  
Sbjct: 966  VEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSV 1025

Query: 801  --DPPPLLTLPRPPLSGALASITETIQVHRRYW 831
               P     L + P   A+A++ + I++  ++W
Sbjct: 1026 ELQPLDEAVLQQKPNINAVATLEKVIEIQSKHW 1058



 Score =  235 bits (599), Expect = 2e-61
 Identities = 147/404 (36%), Positives = 213/404 (52%), Gaps = 33/404 (8%)

Query: 86   TGLVLDEQLNEFHCLWDDSF--PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143
            TG+V D  + +  C+  ++   PE   R+ +I  +L + GLL +C   + R A  +E+  
Sbjct: 683  TGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQT 742

Query: 144  VHSLEYIDLMETTQYMNEGELRV-------------------LADTYDSVYLHPNSYSCA 184
            VHS EY  L+  T  +N  +L                     +    D+V+   +S S  
Sbjct: 743  VHS-EYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAV 801

Query: 185  CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244
             +A G +L L   V   E++NG AIIRPPGHHA+ S   G+C FN VA+ A+  QQK  +
Sbjct: 802  RMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNV 861

Query: 245  RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304
             +VLIVDWD+HHG GTQ  F  DPSVLY S+HRY+ G F+P   A      G G G GY 
Sbjct: 862  GKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAP--EEVGGGPGVGYN 919

Query: 305  INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMAAT 359
            +NV W       + D +Y+ AF  V++P+A EF P +VLV+AGFDA++G   P G  + T
Sbjct: 920  VNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVT 979

Query: 360  PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLG---DPCPMLESPGAP 416
               F  LT  LM LAGG+++L+LEGG++L A+ +   A +  LL     P         P
Sbjct: 980  ARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKP 1039

Query: 417  CRSAQASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEE 460
              +A A++   +E     W  + +    + R ++ E    E+EE
Sbjct: 1040 NINAVATLEKVIEIQSKHWSCVQKFAAGLGR-SLREAQAGETEE 1082


>gi|148539870 histone deacetylase 7 isoform d [Homo sapiens]
          Length = 954

 Score =  285 bits (730), Expect = 1e-76
 Identities = 174/380 (45%), Positives = 222/380 (58%), Gaps = 33/380 (8%)

Query: 481 TGLVYDQNMMNH-CNLWD-SHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
           TGL+YD  M+ H C+  D S HPE   RI  I  RL+E GL  +C  L  R A+  EL +
Sbjct: 522 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 581

Query: 539 CHSAEYVGHLRATEKMKTRELHRESS-------------------NFDSIYICPSTFACA 579
            HS  +V  L  T  +   +L                        + D+I+    +   A
Sbjct: 582 VHSERHV-LLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAA 640

Query: 580 QLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGH 639
           + A G+   L   V S E+ NG AVVRPPGHHA+   A GFCFFNSVA+A R  Q  S  
Sbjct: 641 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQS-K 699

Query: 640 ALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGF 699
           A +ILIVDWDVHHGNGTQ  F  DPSVLY+SLHR+D G FFP    GA  ++G  +G GF
Sbjct: 700 ASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFP--GSGAVDEVGAGSGEGF 757

Query: 700 TVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGD--PLGGCQV 754
            VNVAW G   P MGD +YLAA+  +V+PIA EF+P+LVLVSAGFDAA G   PLGG  V
Sbjct: 758 NVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHV 817

Query: 755 SPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG---DPPPLLTLPRP 811
           S + + ++T  LM LA G ++L LEGG++LT+I ++  AC  +LLG   DP       + 
Sbjct: 818 SAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQK 877

Query: 812 PLSGALASITETIQVHRRYW 831
           P   A+ S+   I+VH +YW
Sbjct: 878 PNLNAIRSLEAVIRVHSKYW 897



 Score =  242 bits (617), Expect = 2e-63
 Identities = 147/384 (38%), Positives = 209/384 (54%), Gaps = 32/384 (8%)

Query: 86  TGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143
           TGL+ D  + +  C   D+   PE   R+ +I  +L + GL  +C   + R A  EEL  
Sbjct: 522 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 581

Query: 144 VHSLEYIDLMETTQY----MNEGELRVL---------------ADTYDSVYLHPNSYSCA 184
           VHS  ++ L  T       ++ G+L  L                DT D+++   +S + A
Sbjct: 582 VHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDT-DTIWNELHSSNAA 640

Query: 185 CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244
             A+GSV  L   V   E++NG A++RPPGHHA HS   G+C FN VA+A R  QQ+ + 
Sbjct: 641 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKA 700

Query: 245 RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304
            ++LIVDWDVHHG GTQ TF QDPSVLY S+HR++ G F+P   A +    G G G+G+ 
Sbjct: 701 SKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVD--EVGAGSGEGFN 758

Query: 305 INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK--GEMAAT 359
           +NV W       M D +Y+AAF  V++P+A EF P LVLV+AGFDA +G P   G    +
Sbjct: 759 VNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS 818

Query: 360 PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPG---AP 416
              F  +T  LM LAGG ++L+LEGG++L A+ +   A +  LLG+    L   G    P
Sbjct: 819 AKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKP 878

Query: 417 CRSAQASVSCALEALEPFWEVLVR 440
             +A  S+   +     +W  + R
Sbjct: 879 NLNAIRSLEAVIRVHSKYWGCMQR 902


>gi|169234807 histone deacetylase 7 isoform a [Homo sapiens]
          Length = 991

 Score =  285 bits (730), Expect = 1e-76
 Identities = 174/380 (45%), Positives = 222/380 (58%), Gaps = 33/380 (8%)

Query: 481 TGLVYDQNMMNH-CNLWD-SHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLT 538
           TGL+YD  M+ H C+  D S HPE   RI  I  RL+E GL  +C  L  R A+  EL +
Sbjct: 559 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 618

Query: 539 CHSAEYVGHLRATEKMKTRELHRESS-------------------NFDSIYICPSTFACA 579
            HS  +V  L  T  +   +L                        + D+I+    +   A
Sbjct: 619 VHSERHV-LLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAA 677

Query: 580 QLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACGFCFFNSVAVAARHAQTISGH 639
           + A G+   L   V S E+ NG AVVRPPGHHA+   A GFCFFNSVA+A R  Q  S  
Sbjct: 678 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQS-K 736

Query: 640 ALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGF 699
           A +ILIVDWDVHHGNGTQ  F  DPSVLY+SLHR+D G FFP    GA  ++G  +G GF
Sbjct: 737 ASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFP--GSGAVDEVGAGSGEGF 794

Query: 700 TVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGD--PLGGCQV 754
            VNVAW G   P MGD +YLAA+  +V+PIA EF+P+LVLVSAGFDAA G   PLGG  V
Sbjct: 795 NVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHV 854

Query: 755 SPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG---DPPPLLTLPRP 811
           S + + ++T  LM LA G ++L LEGG++LT+I ++  AC  +LLG   DP       + 
Sbjct: 855 SAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQK 914

Query: 812 PLSGALASITETIQVHRRYW 831
           P   A+ S+   I+VH +YW
Sbjct: 915 PNLNAIRSLEAVIRVHSKYW 934



 Score =  242 bits (617), Expect = 2e-63
 Identities = 147/384 (38%), Positives = 209/384 (54%), Gaps = 32/384 (8%)

Query: 86  TGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELML 143
           TGL+ D  + +  C   D+   PE   R+ +I  +L + GL  +C   + R A  EEL  
Sbjct: 559 TGLIYDSVMLKHQCSCGDNSRHPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQS 618

Query: 144 VHSLEYIDLMETTQY----MNEGELRVL---------------ADTYDSVYLHPNSYSCA 184
           VHS  ++ L  T       ++ G+L  L                DT D+++   +S + A
Sbjct: 619 VHSERHVLLYGTNPLSRLKLDNGKLAGLLAQRMFVMLPCGGVGVDT-DTIWNELHSSNAA 677

Query: 185 CLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRI 244
             A+GSV  L   V   E++NG A++RPPGHHA HS   G+C FN VA+A R  QQ+ + 
Sbjct: 678 RWAAGSVTDLAFKVASRELKNGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKA 737

Query: 245 RRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYT 304
            ++LIVDWDVHHG GTQ TF QDPSVLY S+HR++ G F+P   A +    G G G+G+ 
Sbjct: 738 SKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVD--EVGAGSGEGFN 795

Query: 305 INVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK--GEMAAT 359
           +NV W       M D +Y+AAF  V++P+A EF P LVLV+AGFDA +G P   G    +
Sbjct: 796 VNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVS 855

Query: 360 PAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPG---AP 416
              F  +T  LM LAGG ++L+LEGG++L A+ +   A +  LLG+    L   G    P
Sbjct: 856 AKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKP 915

Query: 417 CRSAQASVSCALEALEPFWEVLVR 440
             +A  S+   +     +W  + R
Sbjct: 916 NLNAIRSLEAVIRVHSKYWGCMQR 939


>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
          Length = 1069

 Score =  282 bits (722), Expect = 1e-75
 Identities = 169/408 (41%), Positives = 234/408 (57%), Gaps = 39/408 (9%)

Query: 467  PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518
            P   +L  P +       S TG+ YD  M+ H C   +S  HPE   RI  I  RL+E G
Sbjct: 616  PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 675

Query: 519  LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572
            L  +C  +  R A+  E+   HS E+   L  T  +  ++L        +S  F S   C
Sbjct: 676  LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 734

Query: 573  PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619
                           +   A++A G    L   V SGE+ NG AVVRPPGHHAE+  A G
Sbjct: 735  GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 794

Query: 620  FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679
            FCFFNSVA+ A++ +    +  +ILIVD DVHHGNGTQ  F  DPS+LY+SLHRYD G F
Sbjct: 795  FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 853

Query: 680  FPMGDEGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVL 736
            FP    GA +++G   G G+ +N+AW G   P MGD +YL A+  +V P+A EF+P++VL
Sbjct: 854  FP--GSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVL 911

Query: 737  VSAGFDAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAAC 794
            VSAGFDA  G   PLGG +V+ + + HLT  LM LA GR++L LEGG++LT+I ++  AC
Sbjct: 912  VSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEAC 971

Query: 795  TRSLLG---DPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKV 839
              +LLG   +P     L + P   A+ S+ + I++  +YW+S+R++ V
Sbjct: 972  VNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSKYWKSVRMVAV 1019



 Score =  236 bits (603), Expect = 8e-62
 Identities = 143/382 (37%), Positives = 212/382 (55%), Gaps = 32/382 (8%)

Query: 84   AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141
            + TG+  D  + +  C+  +S   PE   R+ +I  +L + GLL++C   Q R A  EE+
Sbjct: 634  SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 693

Query: 142  MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182
             LVHS E+  L+  T  ++  +L  R+L                     D+++   +S  
Sbjct: 694  QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 752

Query: 183  CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242
             A +A G V+ L   V   E++NG A++RPPGHHA+ S   G+C FN VA+ A+Y + + 
Sbjct: 753  AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 812

Query: 243  RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQG 302
             I ++LIVD DVHHG GTQ  F  DPS+LY S+HRY++G F+P   A N    G G G+G
Sbjct: 813  NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGTGLGEG 870

Query: 303  YTINVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMA 357
            Y IN+ W       M D +Y+ AF  ++ PVA EF P +VLV+AGFDAL+G   P G   
Sbjct: 871  YNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYK 930

Query: 358  ATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPC-PMLES--PG 414
             T   F  LT  LM LA G+++L+LEGG++L A+ +   A ++ LLG+   P+ E     
Sbjct: 931  VTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQ 990

Query: 415  APCRSAQASVSCALEALEPFWE 436
            +P  +A  S+   +E    +W+
Sbjct: 991  SPNMNAVISLQKIIEIQSKYWK 1012


>gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]
          Length = 1066

 Score =  282 bits (722), Expect = 1e-75
 Identities = 169/408 (41%), Positives = 234/408 (57%), Gaps = 39/408 (9%)

Query: 467  PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518
            P   +L  P +       S TG+ YD  M+ H C   +S  HPE   RI  I  RL+E G
Sbjct: 613  PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 672

Query: 519  LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572
            L  +C  +  R A+  E+   HS E+   L  T  +  ++L        +S  F S   C
Sbjct: 673  LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 731

Query: 573  PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619
                           +   A++A G    L   V SGE+ NG AVVRPPGHHAE+  A G
Sbjct: 732  GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 791

Query: 620  FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679
            FCFFNSVA+ A++ +    +  +ILIVD DVHHGNGTQ  F  DPS+LY+SLHRYD G F
Sbjct: 792  FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 850

Query: 680  FPMGDEGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVL 736
            FP    GA +++G   G G+ +N+AW G   P MGD +YL A+  +V P+A EF+P++VL
Sbjct: 851  FP--GSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVL 908

Query: 737  VSAGFDAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAAC 794
            VSAGFDA  G   PLGG +V+ + + HLT  LM LA GR++L LEGG++LT+I ++  AC
Sbjct: 909  VSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEAC 968

Query: 795  TRSLLG---DPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKV 839
              +LLG   +P     L + P   A+ S+ + I++  +YW+S+R++ V
Sbjct: 969  VNALLGNELEPLAEDILHQSPNMNAVISLQKIIEIQSKYWKSVRMVAV 1016



 Score =  236 bits (603), Expect = 8e-62
 Identities = 143/382 (37%), Positives = 212/382 (55%), Gaps = 32/382 (8%)

Query: 84   AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141
            + TG+  D  + +  C+  +S   PE   R+ +I  +L + GLL++C   Q R A  EE+
Sbjct: 631  SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 690

Query: 142  MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182
             LVHS E+  L+  T  ++  +L  R+L                     D+++   +S  
Sbjct: 691  QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 749

Query: 183  CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242
             A +A G V+ L   V   E++NG A++RPPGHHA+ S   G+C FN VA+ A+Y + + 
Sbjct: 750  AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 809

Query: 243  RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQG 302
             I ++LIVD DVHHG GTQ  F  DPS+LY S+HRY++G F+P   A N    G G G+G
Sbjct: 810  NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGTGLGEG 867

Query: 303  YTINVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMA 357
            Y IN+ W       M D +Y+ AF  ++ PVA EF P +VLV+AGFDAL+G   P G   
Sbjct: 868  YNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYK 927

Query: 358  ATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPC-PMLES--PG 414
             T   F  LT  LM LA G+++L+LEGG++L A+ +   A ++ LLG+   P+ E     
Sbjct: 928  VTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGNELEPLAEDILHQ 987

Query: 415  APCRSAQASVSCALEALEPFWE 436
            +P  +A  S+   +E    +W+
Sbjct: 988  SPNMNAVISLQKIIEIQSKYWK 1009


>gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens]
          Length = 1011

 Score =  268 bits (686), Expect = 2e-71
 Identities = 164/395 (41%), Positives = 224/395 (56%), Gaps = 39/395 (9%)

Query: 467  PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518
            P   +L  P +       S TG+ YD  M+ H C   +S  HPE   RI  I  RL+E G
Sbjct: 613  PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 672

Query: 519  LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572
            L  +C  +  R A+  E+   HS E+   L  T  +  ++L        +S  F S   C
Sbjct: 673  LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 731

Query: 573  PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619
                           +   A++A G    L   V SGE+ NG AVVRPPGHHAE+  A G
Sbjct: 732  GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 791

Query: 620  FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679
            FCFFNSVA+ A++ +    +  +ILIVD DVHHGNGTQ  F  DPS+LY+SLHRYD G F
Sbjct: 792  FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 850

Query: 680  FPMGDEGASSQIGRAAGTGFTVNVAWNG---PRMGDADYLAAWHRLVLPIAYEFNPELVL 736
            FP    GA +++G   G G+ +N+AW G   P MGD +YL A+  +V P+A EF+P++VL
Sbjct: 851  FP--GSGAPNEVGTGLGEGYNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVL 908

Query: 737  VSAGFDAARG--DPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAAC 794
            VSAGFDA  G   PLGG +V+ + + HLT  LM LA GR++L LEGG++LT+I ++  AC
Sbjct: 909  VSAGFDALEGHTPPLGGYKVTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEAC 968

Query: 795  TRSLLG---DPPPLLTLPRPPLSGALASITETIQV 826
              +LLG   +P     L + P   A+ S+ + I++
Sbjct: 969  VNALLGNELEPLAEDILHQSPNMNAVISLQKIIEI 1003



 Score =  234 bits (596), Expect = 5e-61
 Identities = 136/348 (39%), Positives = 198/348 (56%), Gaps = 29/348 (8%)

Query: 84  AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141
           + TG+  D  + +  C+  +S   PE   R+ +I  +L + GLL++C   Q R A  EE+
Sbjct: 631 SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 690

Query: 142 MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182
            LVHS E+  L+  T  ++  +L  R+L                     D+++   +S  
Sbjct: 691 QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 749

Query: 183 CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242
            A +A G V+ L   V   E++NG A++RPPGHHA+ S   G+C FN VA+ A+Y + + 
Sbjct: 750 AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 809

Query: 243 RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQG 302
            I ++LIVD DVHHG GTQ  F  DPS+LY S+HRY++G F+P   A N    G G G+G
Sbjct: 810 NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN--EVGTGLGEG 867

Query: 303 YTINVPWN---QVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQG--DPKGEMA 357
           Y IN+ W       M D +Y+ AF  ++ PVA EF P +VLV+AGFDAL+G   P G   
Sbjct: 868 YNINIAWTGGLDPPMGDVEYLEAFRTIVKPVAKEFDPDMVLVSAGFDALEGHTPPLGGYK 927

Query: 358 ATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGD 405
            T   F  LT  LM LA G+++L+LEGG++L A+ +   A ++ LLG+
Sbjct: 928 VTAKCFGHLTKQLMTLADGRVVLALEGGHDLTAICDASEACVNALLGN 975


>gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens]
          Length = 879

 Score =  155 bits (391), Expect = 3e-37
 Identities = 101/252 (40%), Positives = 132/252 (52%), Gaps = 31/252 (12%)

Query: 467 PVLPILTWPVLQ------SRTGLVYDQNMMNH-CNLWDSH-HPEVPQRILRIMCRLEELG 518
           P   +L  P +       S TG+ YD  M+ H C   +S  HPE   RI  I  RL+E G
Sbjct: 613 PAASVLPHPAMDRPLQPGSATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETG 672

Query: 519 LAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR------ESSNFDSIYIC 572
           L  +C  +  R A+  E+   HS E+   L  T  +  ++L        +S  F S   C
Sbjct: 673 LLNKCERIQGRKASLEEIQLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPC 731

Query: 573 PS-------------TFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619
                          +   A++A G    L   V SGE+ NG AVVRPPGHHAE+  A G
Sbjct: 732 GGLGVDSDTIWNELHSSGAARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMG 791

Query: 620 FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679
           FCFFNSVA+ A++ +    +  +ILIVD DVHHGNGTQ  F  DPS+LY+SLHRYD G F
Sbjct: 792 FCFFNSVAITAKYLRD-QLNISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNF 850

Query: 680 FPMGDEGASSQI 691
           FP    GA +++
Sbjct: 851 FP--GSGAPNEV 860



 Score =  149 bits (376), Expect = 2e-35
 Identities = 85/229 (37%), Positives = 127/229 (55%), Gaps = 22/229 (9%)

Query: 84  AGTGLVLDEQLNEFHCLWDDS--FPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEEL 141
           + TG+  D  + +  C+  +S   PE   R+ +I  +L + GLL++C   Q R A  EE+
Sbjct: 631 SATGIAYDPLMLKHQCVCGNSTTHPEHAGRIQSIWSRLQETGLLNKCERIQGRKASLEEI 690

Query: 142 MLVHSLEYIDLMETTQYMNEGEL--RVLADT-----------------YDSVYLHPNSYS 182
            LVHS E+  L+  T  ++  +L  R+L                     D+++   +S  
Sbjct: 691 QLVHS-EHHSLLYGTNPLDGQKLDPRILLGDDSQKFFSSLPCGGLGVDSDTIWNELHSSG 749

Query: 183 CACLASGSVLRLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH 242
            A +A G V+ L   V   E++NG A++RPPGHHA+ S   G+C FN VA+ A+Y + + 
Sbjct: 750 AARMAVGCVIELASKVASGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKYLRDQL 809

Query: 243 RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASN 291
            I ++LIVD DVHHG GTQ  F  DPS+LY S+HRY++G F+P   A N
Sbjct: 810 NISKILIVDLDVHHGNGTQQAFYADPSILYISLHRYDEGNFFPGSGAPN 858


>gi|8923769 histone deacetylase 8 [Homo sapiens]
          Length = 377

 Score =  107 bits (267), Expect = 7e-23
 Identities = 84/303 (27%), Positives = 137/303 (45%), Gaps = 15/303 (4%)

Query: 502 EVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHR 561
           ++P+R   +   +E   L  +   + P+ A+  E+ T H+  Y+ HL+   +    + H 
Sbjct: 33  KIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HP 91

Query: 562 ESSNFDSIYICPST---FACAQLATGAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQDAA 617
           +S  +   Y CP+T   F  A    GA     + ++ G  +   A+    G HHA++D A
Sbjct: 92  DSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDG--MCKVAINWSGGWHHAKKDEA 149

Query: 618 CGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHG 677
            GFC+ N   +     +       RIL VD D+HHG+G +  F     V+ VSLH++  G
Sbjct: 150 SGFCYLNDAVLGILRLRR---KFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG 206

Query: 678 TFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLV 737
            FFP    G  S +G   G  ++VNV      + D  Y      ++  +   FNP+ V++
Sbjct: 207 -FFP--GTGDVSDVGLGKGRYYSVNVPIQ-DGIQDEKYYQICESVLKEVYQAFNPKAVVL 262

Query: 738 SAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRS 797
             G D   GDP+    ++P G       ++      +IL   GGYNL + +      T  
Sbjct: 263 QLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLIL-GGGGYNLANTARCWTYLTGV 321

Query: 798 LLG 800
           +LG
Sbjct: 322 ILG 324



 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 77/300 (25%), Positives = 123/300 (41%), Gaps = 34/300 (11%)

Query: 103 DSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEG 162
           DS  + P+R   +   +    L  +    + + A  EE+   H+  Y+  ++      + 
Sbjct: 29  DSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDD 88

Query: 163 ELRVLADTYDSVYLHPNSYSCA----CLASGSVLRLVDAVLGAEIRNGMAII-------- 210
           +             HP+S        C A+  +     A+ GA I     +I        
Sbjct: 89  D-------------HPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAI 135

Query: 211 --RPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDP 268
                 HHA+     G+C  N   +     ++K    R+L VD D+HHG G +  F    
Sbjct: 136 NWSGGWHHAKKDEASGFCYLNDAVLGILRLRRK--FERILYVDLDLHHGDGVEDAFSFTS 193

Query: 269 SVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLL 328
            V+  S+H++  G F+P     + S  G G+G+ Y++NVP  Q G++D  Y      VL 
Sbjct: 194 KVMTVSLHKFSPG-FFP--GTGDVSDVGLGKGRYYSVNVP-IQDGIQDEKYYQICESVLK 249

Query: 329 PVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNL 388
            V   F P+ V++  G D + GDP      TP G  +    ++      LIL   GGYNL
Sbjct: 250 EVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILG-GGGYNL 308


>gi|116284376 histone deacetylase 2 [Homo sapiens]
          Length = 582

 Score =  103 bits (256), Expect = 1e-21
 Identities = 88/332 (26%), Positives = 145/332 (43%), Gaps = 23/332 (6%)

Query: 467 PVLPILTWPVLQSRTG------LVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLA 520
           PV  +   P+  S+ G        YD ++ N+   +   HP  P RI      L   GL 
Sbjct: 86  PVAAVAGEPMAYSQGGGKKKVCYYYDGDIGNY--YYGQGHPMKPHRIRMTHNLLLNYGLY 143

Query: 521 GRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICP---STFA 577
            +     P  AT  E+   HS EY+  LR+       E  ++   F+    CP     F 
Sbjct: 144 RKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFE 203

Query: 578 CAQLATGAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTI 636
             QL+TG +  +  AV         AV    G HHA++  A GFC+ N + +A    + +
Sbjct: 204 FCQLSTGGS--VAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAI--LELL 259

Query: 637 SGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAG 696
             H  R+L +D D+HHG+G +  F     V+ VS H+Y  G +FP    G    IG   G
Sbjct: 260 KYHQ-RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY--GEYFP--GTGDLRDIGAGKG 314

Query: 697 TGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSP 756
             + VN       + D  Y   +  ++  +   + P  V++  G D+  GD LG   ++ 
Sbjct: 315 KYYAVNFPMR-DGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTV 373

Query: 757 EGYAHLTHLLMGLASGRIILILEGGYNLTSIS 788
           +G+A    ++    +  ++++  GGY + +++
Sbjct: 374 KGHAKCVEVVKTF-NLPLLMLGGGGYTIRNVA 404



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 81/292 (27%), Positives = 123/292 (42%), Gaps = 16/292 (5%)

Query: 106 PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELR 165
           P  P R+      L+  GL  +   ++   A  EE+   HS EYI  + + +  N  E  
Sbjct: 124 PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYS 183

Query: 166 VLADTY----DSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHS 220
                +    D          C     GSV     AV     +  MA+    G HHA+ S
Sbjct: 184 KQMQRFNVGEDCPVFDGLFEFCQLSTGGSV---AGAVKLNRQQTDMAVNWAGGLHHAKKS 240

Query: 221 LMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQ 280
              G+C  N + +A     + H+  RVL +D D+HHG G +  F     V+  S H+Y  
Sbjct: 241 EASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY-- 296

Query: 281 GRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVL 340
           G ++P     +    G G+G+ Y +N P    G+ D  Y   F  ++  V   +QP  V+
Sbjct: 297 GEYFP--GTGDLRDIGAGKGKYYAVNFPMRD-GIDDESYGQIFKPIISKVMEMYQPSAVV 353

Query: 341 VAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALA 392
           +  G D+L GD  G    T  G A+   ++       L+L   GGY +R +A
Sbjct: 354 LQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLG-GGGYTIRNVA 404


>gi|13128860 histone deacetylase 1 [Homo sapiens]
          Length = 482

 Score =  102 bits (253), Expect = 3e-21
 Identities = 83/308 (26%), Positives = 137/308 (44%), Gaps = 17/308 (5%)

Query: 485 YDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEY 544
           YD ++ N+   +   HP  P RI      L   GL  +     P  A   E+   HS +Y
Sbjct: 15  YDGDVGNY--YYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDY 72

Query: 545 VGHLRATEKMKTRELHRESSNFDSIYICP---STFACAQLATGAACRLVEAVLSGEVLNG 601
           +  LR+       E  ++   F+    CP     F   QL+TG +  +  AV   +    
Sbjct: 73  IKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGS--VASAVKLNKQQTD 130

Query: 602 AAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMF 660
            AV    G HHA++  A GFC+ N + +A    + +  H  R+L +D D+HHG+G +  F
Sbjct: 131 IAVNWAGGLHHAKKSEASGFCYVNDIVLAI--LELLKYHQ-RVLYIDIDIHHGDGVEEAF 187

Query: 661 EDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWH 720
                V+ VS H+Y  G +FP    G    IG   G  + VN       + D  Y A + 
Sbjct: 188 YTTDRVMTVSFHKY--GEYFP--GTGDLRDIGAGKGKYYAVNYPLR-DGIDDESYEAIFK 242

Query: 721 RLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEG 780
            ++  +   F P  V++  G D+  GD LG   ++ +G+A     +    +  ++++  G
Sbjct: 243 PVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSF-NLPMLMLGGG 301

Query: 781 GYNLTSIS 788
           GY + +++
Sbjct: 302 GYTIRNVA 309



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 82/292 (28%), Positives = 124/292 (42%), Gaps = 16/292 (5%)

Query: 106 PEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELR 165
           P  P R+      L+  GL  +   ++   A  EE+   HS +YI  + + +  N  E  
Sbjct: 29  PMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSIRPDNMSEYS 88

Query: 166 VLADTY----DSVYLHPNSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHS 220
                +    D          C     GSV     AV   + +  +A+    G HHA+ S
Sbjct: 89  KQMQRFNVGEDCPVFDGLFEFCQLSTGGSV---ASAVKLNKQQTDIAVNWAGGLHHAKKS 145

Query: 221 LMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQ 280
              G+C  N + +A     + H+  RVL +D D+HHG G +  F     V+  S H+Y  
Sbjct: 146 EASGFCYVNDIVLAILELLKYHQ--RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKY-- 201

Query: 281 GRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVL 340
           G ++P     +    G G+G+ Y +N P    G+ D  Y A F  V+  V   FQP  V+
Sbjct: 202 GEYFP--GTGDLRDIGAGKGKYYAVNYPLRD-GIDDESYEAIFKPVMSKVMEMFQPSAVV 258

Query: 341 VAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALA 392
           +  G D+L GD  G    T  G A+    +       L+L   GGY +R +A
Sbjct: 259 LQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLG-GGGYTIRNVA 309


>gi|13128862 histone deacetylase 3 [Homo sapiens]
          Length = 428

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 12/292 (4%)

Query: 500 HPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTREL 559
           HP  P R+      +   GL  + +   P  A++ ++   HS +Y+  L+       +  
Sbjct: 22  HPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGF 81

Query: 560 HRESSNF---DSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDA 616
            +  + F   D   + P  F      TGA+ +     L+ ++ + A       HHA++  
Sbjct: 82  TKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQ-LNNKICDIAINWAGGLHHAKKFE 140

Query: 617 ACGFCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDH 676
           A GFC+ N + +     + +  H  R+L +D D+HHG+G Q  F     V+ VS H+Y +
Sbjct: 141 ASGFCYVNDIVIGI--LELLKYHP-RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN 197

Query: 677 GTFFPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVL 736
             FFP    G   ++G  +G  + +NV      + D  Y   +  ++  +   + P  ++
Sbjct: 198 -YFFP--GTGDMYEVGAESGRYYCLNVPLR-DGIDDQSYKHLFQPVINQVVDFYQPTCIV 253

Query: 737 VSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSIS 788
           +  G D+   D LG   +S  G+      +    +  ++++  GGY + +++
Sbjct: 254 LQCGADSLGCDRLGCFNLSIRGHGECVEYVKSF-NIPLLVLGGGGYTVRNVA 304



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 74/311 (23%), Positives = 124/311 (39%), Gaps = 25/311 (8%)

Query: 91  DEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELMLVHSLEYI 150
           D  +  FH  +    P  P RL      ++  GL  + + F+   A + ++   HS +YI
Sbjct: 10  DPDVGNFH--YGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYI 67

Query: 151 DLMET---------TQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVLRLVDAVLGA 201
           D ++          T+ +N   +      +  ++   + Y+ A L   + L      +  
Sbjct: 68  DFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAI 127

Query: 202 EIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKHRIRRVLIVDWDVHHGQGTQ 261
               G+       HHA+     G+C  N + +      + H   RVL +D D+HHG G Q
Sbjct: 128 NWAGGL-------HHAKKFEASGFCYVNDIVIGILELLKYHP--RVLYIDIDIHHGDGVQ 178

Query: 262 FTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIA 321
             F     V+  S H+Y    F+P     +    G   G+ Y +NVP    G+ D  Y  
Sbjct: 179 EAFYLTDRVMTVSFHKY-GNYFFP--GTGDMYEVGAESGRYYCLNVPLRD-GIDDQSYKH 234

Query: 322 AFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILS 381
            F  V+  V   +QP  +++  G D+L  D  G    +  G  +    +       L+L 
Sbjct: 235 LFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLG 294

Query: 382 LEGGYNLRALA 392
             GGY +R +A
Sbjct: 295 -GGGYTVRNVA 304


>gi|217272877 histone deacetylase 11 isoform 1 [Homo sapiens]
          Length = 347

 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 79/320 (24%), Positives = 131/320 (40%), Gaps = 32/320 (10%)

Query: 469 LPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTP 528
           +P   WP++ S     Y+   M    L    HP    +  +++  L+E  L    + +  
Sbjct: 11  VPETRWPIVYSPR---YNITFMGLEKL----HPFDAGKWGKVINFLKEEKLLSDSMLVEA 63

Query: 529 RPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACR 588
           R A+E +LL  H+  Y+  L+ +  + T       +    +   P+     ++      +
Sbjct: 64  REASEEDLLVVHTRRYLNELKWSFAVAT------ITEIPPVIFLPNFLVQRKVLRPLRTQ 117

Query: 589 LVEAVLSGE--VLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVAARHAQTISGHALRILI 645
               +++G+  V  G A+    G HH   D   GFC +  + +A +          R  I
Sbjct: 118 TGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATI 177

Query: 646 VDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTVNVAW 705
           +D D H GNG +  F DD  V  + ++       +P GD  A   I R       V + W
Sbjct: 178 IDLDAHQGNGHERDFMDDKRVYIMDVYNRH---IYP-GDRFAKQAIRRK------VELEW 227

Query: 706 NGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHL 765
                 D +YL    R +     E  P++V+ +AG D   GD LGG  +SP G      L
Sbjct: 228 GTE---DDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDEL 284

Query: 766 LMGLASGR---IILILEGGY 782
           +  +  GR   I+++  GGY
Sbjct: 285 VFRMVRGRRVPILMVTSGGY 304



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 82/320 (25%), Positives = 128/320 (40%), Gaps = 46/320 (14%)

Query: 119 LIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHP 178
           L +E LL   +  +AR A +E+L++VH         T +Y+NE +      T   +   P
Sbjct: 49  LKEEKLLSDSMLVEAREASEEDLLVVH---------TRRYLNELKWSFAVATITEI--PP 97

Query: 179 NSYSCACLASGSVLRLVDAVLGAEI-------RNGMAIIRPPG-HHAQHSLMDGYCMFNH 230
             +    L    VLR +    G  I         G AI    G HH       G+C +  
Sbjct: 98  VIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYAD 157

Query: 231 VAVAARYAQQK-HRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSI---HRYEQGRFWPH 286
           + +A ++  ++   I R  I+D D H G G +  F  D  V    +   H Y   RF   
Sbjct: 158 ITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAK- 216

Query: 287 LKASNWSTTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFD 346
                       Q     + + W   G  D +Y+      +     E  P +V+  AG D
Sbjct: 217 ------------QAIRRKVELEW---GTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTD 261

Query: 347 ALQGDPKGEMAATPAGFAQLTHLLMGLAGGK---LILSLEGGYNLRALAEGVSASLHTLL 403
            L+GD  G ++ +PAG  +   L+  +  G+   +++   GGY  R  A  ++ S+  L 
Sbjct: 262 ILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRT-ARIIADSILNLF 320

Query: 404 GDPCPMLESPGAPCRSAQAS 423
           G     L  P +P  SAQ S
Sbjct: 321 G---LGLIGPESPSVSAQNS 337


>gi|209862883 histone deacetylase 11 isoform 2 [Homo sapiens]
          Length = 296

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 74/286 (25%), Positives = 114/286 (39%), Gaps = 42/286 (14%)

Query: 500 HPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTREL 559
           HP    +  +++  L+E  L    + +  R A+E +LL  H+  Y+  L+   +   R L
Sbjct: 7   HPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELK---RKVLRPL 63

Query: 560 HRESSNFDSIYICPSTFACAQLATGAACRLVEAVLSGEVLNGAAVVRPPGHHAEQDAACG 619
             ++           T    +LA          V  G  +N    V    HH   D   G
Sbjct: 64  RTQTGG---------TIMAGKLA----------VERGWAIN----VGGGFHHCSSDRGGG 100

Query: 620 FCFFNSVAVAARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTF 679
           FC +  + +A +          R  I+D D H GNG +  F DD  V  + ++       
Sbjct: 101 FCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRH---I 157

Query: 680 FPMGDEGASSQIGRAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSA 739
           +P GD  A   I R       V + W      D +YL    R +     E  P++V+ +A
Sbjct: 158 YP-GDRFAKQAIRRK------VELEWGTE---DDEYLDKVERNIKKSLQEHLPDVVVYNA 207

Query: 740 GFDAARGDPLGGCQVSPEGYAHLTHLLMGLASGR---IILILEGGY 782
           G D   GD LGG  +SP G      L+  +  GR   I+++  GGY
Sbjct: 208 GTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGY 253



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 77/313 (24%), Positives = 127/313 (40%), Gaps = 55/313 (17%)

Query: 119 LIQEGLLDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHP 178
           L +E LL   +  +AR A +E+L++VH         T +Y+NE + +VL           
Sbjct: 21  LKEEKLLSDSMLVEAREASEEDLLVVH---------TRRYLNELKRKVLRPL-------- 63

Query: 179 NSYSCACLASGSVLRLVDAVLGAEIRNGMAIIRPPG-HHAQHSLMDGYCMFNHVAVAARY 237
            + +   + +G +           +  G AI    G HH       G+C +  + +A ++
Sbjct: 64  RTQTGGTIMAGKLA----------VERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKF 113

Query: 238 AQQK-HRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSI---HRYEQGRFWPHLKASNWS 293
             ++   I R  I+D D H G G +  F  D  V    +   H Y   RF          
Sbjct: 114 LFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAK-------- 165

Query: 294 TTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPK 353
                Q     + + W   G  D +Y+      +     E  P +V+  AG D L+GD  
Sbjct: 166 -----QAIRRKVELEW---GTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRL 217

Query: 354 GEMAATPAGFAQLTHLLMGLAGGK---LILSLEGGYNLRALAEGVSASLHTLLGDPCPML 410
           G ++ +PAG  +   L+  +  G+   +++   GGY  R  A  ++ S+  L G     L
Sbjct: 218 GGLSISPAGIVKRDELVFRMVRGRRVPILMVTSGGYQKRT-ARIIADSILNLFG---LGL 273

Query: 411 ESPGAPCRSAQAS 423
             P +P  SAQ S
Sbjct: 274 IGPESPSVSAQNS 286


>gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]
          Length = 640

 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 27/58 (46%), Positives = 34/58 (58%)

Query: 1133 CGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYV 1190
            C +C T +  W CL C  V CGRYI  H L+H   +GHPL +   DL  +CY C+ YV
Sbjct: 26   CLECATTESVWACLKCSHVACGRYIEDHALKHFEETGHPLAMEVRDLYVFCYLCKDYV 83


>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
          Length = 712

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 27/58 (46%), Positives = 33/58 (56%)

Query: 1133 CGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYV 1190
            C DC T +  W CLSC  V CGRYI  H L+H   S HP+ L   ++  +CY C  YV
Sbjct: 29   CVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86


>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
          Length = 712

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 27/58 (46%), Positives = 33/58 (56%)

Query: 1133 CGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYV 1190
            C DC T +  W CLSC  V CGRYI  H L+H   S HP+ L   ++  +CY C  YV
Sbjct: 29   CVDCNTTESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 47/171 (27%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G EST     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 99   VSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 158

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 159  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 214

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 215  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 265



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%)

Query: 881  KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935
            ++T+AS  G E+T   T  SET   +    + + A+T G+   T + T SE  +   M  
Sbjct: 742  EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 801

Query: 936  QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983
            +TT    +G  T   +T            SE T+      +TT+    G  T+  +T+  
Sbjct: 802  ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 859

Query: 984  AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039
               G+    TTS    E  T     SE     TE  +T  A++   +T  T+  +G    
Sbjct: 860  ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 915

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            TT      T   S    E+ + S   SE+     E
Sbjct: 916  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 950



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 61/250 (24%), Positives = 96/250 (38%), Gaps = 16/250 (6%)

Query: 846  SSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFG--EESTPGQTNSETAVV 903
            SS    T  AP           T  E   +     + T+AS    E +TP  T S+T +V
Sbjct: 20   SSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIV 79

Query: 904  ALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT-----SEETVG 958
            +++  + +  +T G+    T+S A  G        SE  +  A  + TT     +E T+ 
Sbjct: 80   SISGSEITTTSTAGSE-NTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMV 138

Query: 959  GAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTEL 1018
             A+  +TT+       T   T +  A    T   T         T D  T+  +  G+E+
Sbjct: 139  SAMGSETTTNSTTSSET---TVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 195

Query: 1019 IQTPLASSTDHQTPPTSPVQGTTPQISPS-TLIGSLRTLELGSESQGASESQAP---GEE 1074
              T   + ++  TP T+  + TT   + S T   S    E  + S   SE+ A    G E
Sbjct: 196  -TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSE 254

Query: 1075 NLLGEAAGGQ 1084
                  AG +
Sbjct: 255  TTKVSTAGSE 264



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 628  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 686

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++  TTS    E 
Sbjct: 687  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 743

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 744  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 802

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 803  TTMAS 807



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET     T  + SE  T   T ++T + 
Sbjct: 700  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 756

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 757  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 816

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 817  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 874

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 875  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 933



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 349  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 408

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 409  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 467

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 468  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 527

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 528  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 587

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 588  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 646

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 647  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 706

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 707  STEGSG 712



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 980  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1035

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1036 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1094

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1095 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1154

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1155 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1210

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1211 GSETTTASTAGSE 1223



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 161  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 220

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 221  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 276

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 277  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 336

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 337  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 388



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 658  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 717

Query: 941  EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000
                  T  +TT   T G    + TT+       T    T  E    +T    T+ A+ E
Sbjct: 718  -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 769

Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
            G+   +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 770  GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 820



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 896  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 955

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 956  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 1015

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 1016 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1075

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1076 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1119



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1057 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1115

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991
                  SE      T  +TT+  T G  A    TTS +    +T G   SE      T++
Sbjct: 1116 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1172

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049
            +TT  S    E  T     SE     TE  +T  AS+   +T   S     T   S S  
Sbjct: 1173 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1230

Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075
             GS       + S+ ++ S A  E N
Sbjct: 1231 -GSETNTACTTGSETSTPSSAGSETN 1255



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 567  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 626

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 627  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 686

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 687  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 743

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 744  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 782



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 309  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 368

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 369  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 422

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 423  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 481

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 482  SETTTVTTAGSETKTAYTTGSETTTASNT 510



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 880  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 939

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 940  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 995

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 996  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1049

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1050 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1098



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914
            TT  +  + + MG  T+  ++ G E+T   T           NSET + + T  + +  +
Sbjct: 788  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 847

Query: 915  TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974
            T G+   +TI  A+  G+    TTS E     T     SE T       +TT+   +G  
Sbjct: 848  TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 903

Query: 975  TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021
            T   TT+      +T    T+  + EG+             T+  T SE     TE  +T
Sbjct: 904  T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 954

Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079
              AS+   +    S     T  +S     GS  T    +GSE+  AS +   G E     
Sbjct: 955  TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 1008

Query: 1080 AAGGQDMADSMLMQGSRGLT 1099
             AG +    S  ++GS   T
Sbjct: 1009 TAGSETTTAS--IEGSETTT 1026



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 601  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 653

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 654  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 710

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 711  SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 764

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 765  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 799



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 874  VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919
            V  +G G  T+++ G E+T                SE   V+ T  + + A+T G+   T
Sbjct: 1107 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1166

Query: 920  LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973
            +  T+SE      +  + T+  A G           +TT+  T G    + TT+  A   
Sbjct: 1167 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1223

Query: 974  ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030
             T   T+  E     T    TS  +  G+  +      SE     T  ++    S T  +
Sbjct: 1224 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1283

Query: 1031 TPPTS 1035
            T   S
Sbjct: 1284 TTTVS 1288


>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
          Length = 520

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 31/100 (31%), Positives = 46/100 (46%), Gaps = 22/100 (22%)

Query: 1113 CPHLVA-VCPIPAA-----GLDVTQPCGDCGTIQENWVCLSCYQVYCGRYINGHMLQHHG 1166
            CPHL + VC  P +     G   +  C  C + +  WVCL+C  V+CGRY+NGH  +H+ 
Sbjct: 3    CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYE 62

Query: 1167 NSGHPLV----------------LSYIDLSAWCYYCQAYV 1190
            ++  PL                 +     S +CY C  +V
Sbjct: 63   DAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFV 102


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G E+T     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 78   VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 138  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%)

Query: 881  KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935
            ++T+AS  G E+T   T  SET   +    + + A+T G+   T + T SE  +   M  
Sbjct: 721  EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 936  QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983
            +TT    +G  T   +T            SE T+      +TT+    G  T+  +T+  
Sbjct: 781  ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838

Query: 984  AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039
               G+    TTS    E  T     SE     TE  +T  A++   +T  T+  +G    
Sbjct: 839  ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            TT      T   S    E+ + S   SE+     E
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            +++A      S +  E +TP  T S+T +V+++  + +  +T G+    T+S A  G   
Sbjct: 29   LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991
               TT+    G  T   T   ET   +I   +TT   A+G   T   TTS E    +T  
Sbjct: 85   ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 992  QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045
              T+  +  G+      T D  T+  +  G+E+  T   + ++  TP T+  + TT   +
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084
             S T   S    E  + S   SE+ A    G E      AG +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++  TTS    E 
Sbjct: 666  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 782  TTMAS 786



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET     T  + SE  T   T ++T + 
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 796  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 20/244 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V  +G G  T+++ G         SET  V +T  + + A+T G+  A T+S  +     
Sbjct: 1086 VSTSGSGTTTASTAG---------SETTTVYITGSKTTTASTEGSE-ATTVSTTSSETTT 1135

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ- 992
               T SE      T  +TT+  T+G    + TTS  A   AT   T   E    +T    
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGS---EATTSSAAGSEATTTSTEGSETTTASTAGSE 1192

Query: 993  --TTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLI 1050
              T S A  E  T     SE     T   +T  A +T  +T   S     T   + + +I
Sbjct: 1193 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET---NTAFII 1249

Query: 1051 GSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPL 1110
            GS  T+   +  +  + S    E   +   A G   A + +   +  LT +A   ++ P+
Sbjct: 1250 GSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLT-KATDVSIQPI 1308

Query: 1111 PWCP 1114
               P
Sbjct: 1309 TNTP 1312



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 328  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 388  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 447  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 507  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 567  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 686  STEGSG 691



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 959  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1190 GSETTTASTAGSE 1202



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 140  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 256  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 316  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 58/213 (27%), Positives = 80/213 (37%), Gaps = 15/213 (7%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQ------TTSEEAV 985
                  SE      T  +TT+  T G  A    TTS +    +T G       TT  E  
Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154

Query: 986  GGATL---AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTP 1042
              +T+   A T+S A  E  T     SE     T   +T  AS+   +T   S     T 
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETT 1214

Query: 1043 QISPSTLIGSLRTLELGSESQGASESQAPGEEN 1075
              S S   GS       + S+ ++ S A  E N
Sbjct: 1215 TASTS---GSETNTACTTGSETSTPSSAGSETN 1244



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 637  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 941  EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000
                  T  +TT   T G    + TT+       T    T  E    +T    T+ A+ E
Sbjct: 697  -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
            G+   +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 749  GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 875  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 935  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 723  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 288  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 348  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNT 489



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 919  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 975  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914
            TT  +  + + MG  T+  ++ G E+T   T           NSET + + T  + +  +
Sbjct: 767  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826

Query: 915  TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974
            T G+   +TI  A+  G+    TTS E     T     SE T       +TT+   +G  
Sbjct: 827  TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882

Query: 975  TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021
            T   TT+      +T    T+  + EG+             T+  T SE     TE  +T
Sbjct: 883  T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079
              AS+   +    S     T  +S     GS  T    +GSE+  AS +   G E     
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987

Query: 1080 AAGGQDMADSMLMQGSRGLT 1099
             AG +    S  ++GS   T
Sbjct: 988  TAGSETTTAS--IEGSETTT 1005



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%)

Query: 882  VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929
            V  A+    +T   T SET  + +   + + A+T G+   T + T S+  I         
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 930  --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985
                A    TT   A  G T       ET       +TT+    G  T  +    SE   
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 986  GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043
               T ++T  TS A  E  T+    SE     T   +T  AS+T  +   T+     +  
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184

Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091
            I+PST      T+   GSE+   S +   G E      A  +  A S +
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 690  SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G E+T     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 78   VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 138  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%)

Query: 881  KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935
            ++T+AS  G E+T   T  SET   +    + + A+T G+   T + T SE  +   M  
Sbjct: 721  EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 936  QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983
            +TT    +G  T   +T            SE T+      +TT+    G  T+  +T+  
Sbjct: 781  ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838

Query: 984  AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039
               G+    TTS    E  T     SE     TE  +T  A++   +T  T+  +G    
Sbjct: 839  ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            TT      T   S    E+ + S   SE+     E
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            +++A      S +  E +TP  T S+T +V+++  + +  +T G+    T+S A  G   
Sbjct: 29   LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991
               TT+    G  T   T   ET   +I   +TT   A+G   T   TTS E    +T  
Sbjct: 85   ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 992  QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045
              T+  +  G+      T D  T+  +  G+E+  T   + ++  TP T+  + TT   +
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084
             S T   S    E  + S   SE+ A    G E      AG +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++  TTS    E 
Sbjct: 666  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 782  TTMAS 786



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET     T  + SE  T   T ++T + 
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 796  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 328  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 388  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 447  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 507  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 567  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 686  STEGSG 691



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 959  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1190 GSETTTASTAGSE 1202



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 140  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 256  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 316  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 637  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 941  EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000
                  T  +TT   T G    + TT+       T    T  E    +T    T+ A+ E
Sbjct: 697  -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
            G+   +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 749  GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 875  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 935  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991
                  SE      T  +TT+  T G  A    TTS +    +T G   SE      T++
Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049
            +TT  S    E  T     SE     TE  +T  AS+   +T   S     T   S S  
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209

Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075
             GS       + S+ ++ S A  E N
Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 723  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 288  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 348  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNT 489



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 919  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 975  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914
            TT  +  + + MG  T+  ++ G E+T   T           NSET + + T  + +  +
Sbjct: 767  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826

Query: 915  TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974
            T G+   +TI  A+  G+    TTS E     T     SE T       +TT+   +G  
Sbjct: 827  TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882

Query: 975  TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021
            T   TT+      +T    T+  + EG+             T+  T SE     TE  +T
Sbjct: 883  T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079
              AS+   +    S     T  +S     GS  T    +GSE+  AS +   G E     
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987

Query: 1080 AAGGQDMADSMLMQGSRGLT 1099
             AG +    S  ++GS   T
Sbjct: 988  TAGSETTTAS--IEGSETTT 1005



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%)

Query: 882  VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929
            V  A+    +T   T SET  + +   + + A+T G+   T + T S+  I         
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 930  --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985
                A    TT   A  G T       ET       +TT+    G  T  +    SE   
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 986  GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043
               T ++T  TS A  E  T+    SE     T   +T  AS+T  +   T+     +  
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184

Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091
            I+PST      T+   GSE+   S +   G E      A  +  A S +
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 690  SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 874  VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919
            V  +G G  T+++ G E+T                SE   V+ T  + + A+T G+   T
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 920  LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973
            +  T+SE      +  + T+  A G           +TT+  T G    + TT+  A   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202

Query: 974  ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030
             T   T+  E     T    TS  +  G+  +      SE     T  ++    S T  +
Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262

Query: 1031 TPPTS 1035
            T   S
Sbjct: 1263 TTTVS 1267


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G E+T     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 78   VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 138  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%)

Query: 881  KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935
            ++T+AS  G E+T   T  SET   +    + + A+T G+   T + T SE  +   M  
Sbjct: 721  EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 936  QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983
            +TT    +G  T   +T            SE T+      +TT+    G  T+  +T+  
Sbjct: 781  ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838

Query: 984  AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039
               G+    TTS    E  T     SE     TE  +T  A++   +T  T+  +G    
Sbjct: 839  ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            TT      T   S    E+ + S   SE+     E
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            +++A      S +  E +TP  T S+T +V+++  + +  +T G+    T+S A  G   
Sbjct: 29   LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991
               TT+    G  T   T   ET   +I   +TT   A+G   T   TTS E    +T  
Sbjct: 85   ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 992  QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045
              T+  +  G+      T D  T+  +  G+E+  T   + ++  TP T+  + TT   +
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084
             S T   S    E  + S   SE+ A    G E      AG +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++  TTS    E 
Sbjct: 666  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 782  TTMAS 786



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET     T  + SE  T   T ++T + 
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 796  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 328  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 388  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 447  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 507  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 567  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 686  STEGSG 691



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 959  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1190 GSETTTASTAGSE 1202



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 140  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 256  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 316  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 637  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 941  EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000
                  T  +TT   T G    + TT+       T    T  E    +T    T+ A+ E
Sbjct: 697  -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
            G+   +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 749  GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 875  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 935  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991
                  SE      T  +TT+  T G  A    TTS +    +T G   SE      T++
Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049
            +TT  S    E  T     SE     TE  +T  AS+   +T   S     T   S S  
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209

Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075
             GS       + S+ ++ S A  E N
Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 723  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 288  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 348  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNT 489



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 919  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 975  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914
            TT  +  + + MG  T+  ++ G E+T   T           NSET + + T  + +  +
Sbjct: 767  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826

Query: 915  TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974
            T G+   +TI  A+  G+    TTS E     T     SE T       +TT+   +G  
Sbjct: 827  TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882

Query: 975  TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021
            T   TT+      +T    T+  + EG+             T+  T SE     TE  +T
Sbjct: 883  T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079
              AS+   +    S     T  +S     GS  T    +GSE+  AS +   G E     
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987

Query: 1080 AAGGQDMADSMLMQGSRGLT 1099
             AG +    S  ++GS   T
Sbjct: 988  TAGSETTTAS--IEGSETTT 1005



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%)

Query: 882  VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929
            V  A+    +T   T SET  + +   + + A+T G+   T + T S+  I         
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 930  --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985
                A    TT   A  G T       ET       +TT+    G  T  +    SE   
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 986  GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043
               T ++T  TS A  E  T+    SE     T   +T  AS+T  +   T+     +  
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184

Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091
            I+PST      T+   GSE+   S +   G E      A  +  A S +
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 690  SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 874  VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919
            V  +G G  T+++ G E+T                SE   V+ T  + + A+T G+   T
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 920  LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973
            +  T+SE      +  + T+  A G           +TT+  T G    + TT+  A   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202

Query: 974  ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030
             T   T+  E     T    TS  +  G+  +      SE     T  ++    S T  +
Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSE 1262

Query: 1031 TPPTS 1035
            T   S
Sbjct: 1263 TTTVS 1267


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G E+T     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 78   VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 138  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 57/228 (25%), Positives = 88/228 (38%), Gaps = 27/228 (11%)

Query: 868  TTREKKVLEAGMGKVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQ 922
            T  E  +      ++T+AS  G E+T   T  SET   +    + + A+T G+   T + 
Sbjct: 708  TGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTAST 767

Query: 923  TISEAAIGGAMLGQTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDA 970
            T SE  +   M  +TT    +G  T   +T            SE T+      +TT+   
Sbjct: 768  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827

Query: 971  VGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQ 1030
             G  T+  +T+     G+    TTS    E  T     SE     TE  +T  A++   +
Sbjct: 828  AGSETIPASTA-----GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882

Query: 1031 TPPTSPVQG----TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            T  T+  +G    TT      T   S    E+ + S   SE+     E
Sbjct: 883  T-TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 58/240 (24%), Positives = 92/240 (38%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET +   T  + SE  T   T ++T + 
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTI---TSTEGSEITTASITGSETTTA 735

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 796  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            +++A      S +  E +TP  T S+T +V+++  + +  +T G+    T+S A  G   
Sbjct: 29   LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991
               TT+    G  T   T   ET   +I   +TT   A+G   T   TTS E    +T  
Sbjct: 85   ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 992  QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045
              T+  +  G+      T D  T+  +  G+E+  T   + ++  TP T+  + TT   +
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084
             S T   S    E  + S   SE+ A    G E      AG +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQT--TSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++T  TS    E 
Sbjct: 666  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEI 722

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 782  TTMAS 786



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 328  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 388  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 447  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 507  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 567  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 686  STEGSG 691



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 959  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1190 GSETTTASTAGSE 1202



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 140  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 256  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 316  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 875  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 935  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991
                  SE      T  +TT+  T G  A    TTS +    +T G   SE      T++
Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049
            +TT  S    E  T     SE     TE  +T  AS+   +T   S     T   S S  
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209

Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075
             GS       + S+ ++ S A  E N
Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 12/170 (7%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 637  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 941  EAVGGATPDQTTSEETVGG--AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAA 998
                  T  +TT   T G    I     SE      T  +TT+    G  T   T S   
Sbjct: 697  -----ITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSET--TTASTEG 749

Query: 999  MEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
             E  +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITS-TEGS--EI 722

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 723  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 288  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 348  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNT 489



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 50/226 (22%), Positives = 80/226 (35%), Gaps = 19/226 (8%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTIS 925
            TT  +  + + MG  T+  ++ G E+T   T S       T++  +  A+  A+   T+S
Sbjct: 767  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826

Query: 926  EAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAV 985
             A       G  T   +  G+    TTS E           SE         +TT+   +
Sbjct: 827  TA-------GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI 879

Query: 986  GGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT---- 1041
            G  T   T S    E  T     SE     TE  +    S+T  +T   S     T    
Sbjct: 880  GSET--TTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAS 937

Query: 1042 ---PQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
                +++  +  GS  T+ + +E    +     G E      AG +
Sbjct: 938  TEGSELTTVSTTGS-ETITVSAEGSETTTVTTMGSETTTASTAGSE 982



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 919  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 975  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%)

Query: 882  VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929
            V  A+    +T   T SET  + +   + + A+T G+   T + T S+  I         
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 930  --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985
                A    TT   A  G T       ET       +TT+    G  T  +    SE   
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 986  GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043
               T ++T  TS A  E  T+    SE     T   +T  AS+T  +   T+     +  
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184

Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091
            I+PST      T+   GSE+   S +   G E      A  +  A S +
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 690  SGTTTVSITGSETTKVSTTGSETTIT----STEGSEITTASITGS--ETTTASTEGSETT 743

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 874  VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919
            V  +G G  T+++ G E+T                SE   V+ T  + + A+T G+   T
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 920  LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973
            +  T+SE      +  + T+  A G           +TT+  T G    + TT+  A   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202

Query: 974  ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030
             T   T+  E     T    TS  +  G+  +      SE     T  ++    S T  +
Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262

Query: 1031 TPPTS 1035
            T   S
Sbjct: 1263 TTTVS 1267


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G E+T     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 78   VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 138  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%)

Query: 881  KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935
            ++T+AS  G E+T   T  SET   +    + + A+T G+   T + T SE  +   M  
Sbjct: 721  EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 936  QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983
            +TT    +G  T   +T            SE T+      +TT+    G  T+  +T+  
Sbjct: 781  ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838

Query: 984  AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039
               G+    TTS    E  T     SE     TE  +T  A++   +T  T+  +G    
Sbjct: 839  ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            TT      T   S    E+ + S   SE+     E
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            +++A      S +  E +TP  T S+T +V+++  + +  +T G+    T+S A  G   
Sbjct: 29   LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991
               TT+    G  T   T   ET   +I   +TT   A+G   T   TTS E    +T  
Sbjct: 85   ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 992  QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045
              T+  +  G+      T D  T+  +  G+E+  T   + ++  TP T+  + TT   +
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084
             S T   S    E  + S   SE+ A    G E      AG +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++  TTS    E 
Sbjct: 666  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 782  TTMAS 786



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET     T  + SE  T   T ++T + 
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 796  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 328  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 388  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 447  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 507  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 567  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 686  STEGSG 691



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 959  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1190 GSETTTASTAGSE 1202



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 140  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 256  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 316  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 637  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 941  EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000
                  T  +TT   T G    + TT+       T    T  E    +T    T+ A+ E
Sbjct: 697  -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
            G+   +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 749  GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 875  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 935  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991
                  SE      T  +TT+  T G  A    TTS +    +T G   SE      T++
Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049
            +TT  S    E  T     SE     TE  +T  AS+   +T   S     T   S S  
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209

Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075
             GS       + S+ ++ S A  E N
Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 723  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 288  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 348  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNT 489



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 919  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 975  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914
            TT  +  + + MG  T+  ++ G E+T   T           NSET + + T  + +  +
Sbjct: 767  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826

Query: 915  TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974
            T G+   +TI  A+  G+    TTS E     T     SE T       +TT+   +G  
Sbjct: 827  TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882

Query: 975  TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021
            T   TT+      +T    T+  + EG+             T+  T SE     TE  +T
Sbjct: 883  T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079
              AS+   +    S     T  +S     GS  T    +GSE+  AS +   G E     
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987

Query: 1080 AAGGQDMADSMLMQGSRGLT 1099
             AG +    S  ++GS   T
Sbjct: 988  TAGSETTTAS--IEGSETTT 1005



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%)

Query: 882  VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929
            V  A+    +T   T SET  + +   + + A+T G+   T + T S+  I         
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 930  --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985
                A    TT   A  G T       ET       +TT+    G  T  +    SE   
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 986  GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043
               T ++T  TS A  E  T+    SE     T   +T  AS+T  +   T+     +  
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184

Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091
            I+PST      T+   GSE+   S +   G E      A  +  A S +
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 690  SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 874  VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919
            V  +G G  T+++ G E+T                SE   V+ T  + + A+T G+   T
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 920  LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973
            +  T+SE      +  + T+  A G           +TT+  T G    + TT+  A   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202

Query: 974  ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030
             T   T+  E     T    TS  +  G+  +      SE     T  ++    S T  +
Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262

Query: 1031 TPPTS 1035
            T   S
Sbjct: 1263 TTTVS 1267


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G E+T     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 78   VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 138  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%)

Query: 881  KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935
            ++T+AS  G E+T   T  SET   +    + + A+T G+   T + T SE  +   M  
Sbjct: 721  EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 936  QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983
            +TT    +G  T   +T            SE T+      +TT+    G  T+  +T+  
Sbjct: 781  ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838

Query: 984  AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039
               G+    TTS    E  T     SE     TE  +T  A++   +T  T+  +G    
Sbjct: 839  ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            TT      T   S    E+ + S   SE+     E
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            +++A      S +  E +TP  T S+T +V+++  + +  +T G+    T+S A  G   
Sbjct: 29   LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991
               TT+    G  T   T   ET   +I   +TT   A+G   T   TTS E    +T  
Sbjct: 85   ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 992  QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045
              T+  +  G+      T D  T+  +  G+E+  T   + ++  TP T+  + TT   +
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084
             S T   S    E  + S   SE+ A    G E      AG +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++  TTS    E 
Sbjct: 666  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 782  TTMAS 786



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET     T  + SE  T   T ++T + 
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 796  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 328  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 388  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 447  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 507  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 567  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 686  STEGSG 691



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 959  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1190 GSETTTASTAGSE 1202



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 140  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 256  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 316  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 637  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 941  EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000
                  T  +TT   T G    + TT+       T    T  E    +T    T+ A+ E
Sbjct: 697  -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
            G+   +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 749  GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 875  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 935  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 57/206 (27%), Positives = 79/206 (38%), Gaps = 11/206 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQTTSEEAVGGATLA 991
                  SE      T  +TT+  T G  A    TTS +    +T G   SE      T++
Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTG---SEMTTVFTTVS 1151

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTL 1049
            +TT  S    E  T     SE     TE  +T  AS+   +T   S     T   S S  
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS-- 1209

Query: 1050 IGSLRTLELGSESQGASESQAPGEEN 1075
             GS       + S+ ++ S A  E N
Sbjct: 1210 -GSETNTACTTGSETSTPSSAGSETN 1234



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 723  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 288  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 348  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNT 489



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 919  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 975  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914
            TT  +  + + MG  T+  ++ G E+T   T           NSET + + T  + +  +
Sbjct: 767  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826

Query: 915  TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974
            T G+   +TI  A+  G+    TTS E     T     SE T       +TT+   +G  
Sbjct: 827  TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882

Query: 975  TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021
            T   TT+      +T    T+  + EG+             T+  T SE     TE  +T
Sbjct: 883  T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079
              AS+   +    S     T  +S     GS  T    +GSE+  AS +   G E     
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987

Query: 1080 AAGGQDMADSMLMQGSRGLT 1099
             AG +    S  ++GS   T
Sbjct: 988  TAGSETTTAS--IEGSETTT 1005



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%)

Query: 882  VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929
            V  A+    +T   T SET  + +   + + A+T G+   T + T S+  I         
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 930  --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985
                A    TT   A  G T       ET       +TT+    G  T  +    SE   
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 986  GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043
               T ++T  TS A  E  T+    SE     T   +T  AS+T  +   T+     +  
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184

Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091
            I+PST      T+   GSE+   S +   G E      A  +  A S +
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 690  SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 42/185 (22%), Positives = 68/185 (36%), Gaps = 26/185 (14%)

Query: 874  VLEAGMGKVTSASFGEESTP-----------GQTNSETAVVALTQDQPSEAATGGA---T 919
            V  +G G  T+++ G E+T                SE   V+ T  + + A+T G+   T
Sbjct: 1086 VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT 1145

Query: 920  LAQTISEAAIGGAMLGQTTSEEAVGGATP------DQTTSEETVGGAILDQTTSEDAVGG 973
            +  T+SE      +  + T+  A G           +TT+  T G    + TT+  A   
Sbjct: 1146 VFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---ETTTASTAGSE 1202

Query: 974  ATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQT---TSEEAPGGTELIQTPLASSTDHQ 1030
             T   T+  E     T    TS  +  G+  +      SE     T  ++    S T  +
Sbjct: 1203 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSE 1262

Query: 1031 TPPTS 1035
            T   S
Sbjct: 1263 TTTVS 1267


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 7/171 (4%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIG 930
            V  AG G  T++  G E+T     SET  V++T  + +  +  G+   T + T SE  + 
Sbjct: 78   VSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVT 137

Query: 931  GAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATL 990
                 +TT+   VG  T    T++     A    TT  +     T G  T   +  G+  
Sbjct: 138  STAGSETTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSE- 193

Query: 991  AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTT 1041
              T S A  E  T+  T SE     T   +T  AS+   +T   S     T
Sbjct: 194  TTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 244



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 55/215 (25%), Positives = 85/215 (39%), Gaps = 27/215 (12%)

Query: 881  KVTSASF-GEESTPGQTN-SETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLG 935
            ++T+AS  G E+T   T  SET   +    + + A+T G+   T + T SE  +   M  
Sbjct: 721  EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS 780

Query: 936  QTTSEEAVGGATPDQTT------------SEETVGGAILDQTTSEDAVGGATLGQTTSEE 983
            +TT    +G  T   +T            SE T+      +TT+    G  T+  +T+  
Sbjct: 781  ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA-- 838

Query: 984  AVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG---- 1039
               G+    TTS    E  T     SE     TE  +T  A++   +T  T+  +G    
Sbjct: 839  ---GSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET-TTASTEGSETT 894

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASESQAPGEE 1074
            TT      T   S    E+ + S   SE+     E
Sbjct: 895  TTSTEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 58/223 (26%), Positives = 94/223 (42%), Gaps = 20/223 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            +++A      S +  E +TP  T S+T +V+++  + +  +T G+    T+S A  G   
Sbjct: 29   LIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSE-NTTVSSAGSG--- 84

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAIL-DQTTSEDAVGG-ATLGQTTSEEAVGGATLA 991
               TT+    G  T   T   ET   +I   +TT   A+G   T   TTS E    +T  
Sbjct: 85   ---TTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAG 141

Query: 992  QTTSEAAMEGA------TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQIS 1045
              T+  +  G+      T D  T+  +  G+E+  T   + ++  TP T+  + TT   +
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEM-TTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1046 PS-TLIGSLRTLELGSESQGASESQAP---GEENLLGEAAGGQ 1084
             S T   S    E  + S   SE+ A    G E      AG +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSE 243



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 7/185 (3%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAV 943
            S +  E ++   T SET   + T  + + A+T G+    T+S       M+  T SE  +
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTTASTEGSETT-TVSTTDSETTMVSTTGSERTI 665

Query: 944  GGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ--TTSEAAMEG 1001
                  +TT+    G    + T S +  G  T+  T SE      T ++  TTS    E 
Sbjct: 666  TSTEGSETTTVSATGS---ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 722

Query: 1002 ATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSE 1061
             T   T SE     TE  +T  AS+   +T   S     T   S ++   ++ ++ +GSE
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI-MGSE 781

Query: 1062 SQGAS 1066
            +  AS
Sbjct: 782  TTMAS 786



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 58/240 (24%), Positives = 91/240 (37%), Gaps = 29/240 (12%)

Query: 868  TTREKKVLEAGMGKVTSASFGEESTP-GQTNSETAVVALTQDQPSEAATGGATLAQTISE 926
            T  E  V   G G  T +  G E+T    T SET     T  + SE  T   T ++T + 
Sbjct: 679  TGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT---TSTEGSEITTASITGSETTTA 735

Query: 927  AAIGGAMLGQTT--SEEAVGGATPDQTT------SEETVGGAILDQTTSEDAVGGATLGQ 978
            +  G      +T  SE      T  +TT      SE T+   +  +TT    +G  T   
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 979  TTSEEAVGGATLAQTTSEAAMEGATLDQTT------SEEAPGGTELIQTPLASSTDHQTP 1032
            +T+   +   T+    SE  +   T  +TT      SE  P  T   +T   +ST+    
Sbjct: 796  STASSKM--TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSET 853

Query: 1033 PTSPVQGT--------TPQISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
             T+  +G+        + + + +T IGS  T    +E    + +   G E       G +
Sbjct: 854  TTASTEGSETTTASTESSETTTATTIGS-ETTTASTEGSETTTTSTEGSETTTASTEGSE 912



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 20/244 (8%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V  +G G  T+++ G         SET  V +T  + + A+T G+  A T+S  +     
Sbjct: 1086 VSTSGSGTTTASTAG---------SETTTVYITGSKTTTASTEGSE-ATTVSTTSSETTT 1135

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ- 992
               T SE      T  +TT+  T+G    + TTS  A   AT   T   E    +T    
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGS---EATTSSAAGSEATTTSTEGSETTTASTAGSE 1192

Query: 993  --TTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLI 1050
              T S A  E  T     SE     T   +T  A +T  +T   S     T   + + +I
Sbjct: 1193 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSET---NTAFII 1249

Query: 1051 GSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLMQGSRGLTDQAIFYAVTPL 1110
            GS  T+   +  +  + S    E   +   A G   A + +   +  LT +A   ++ P+
Sbjct: 1250 GSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLT-KATDVSIQPI 1308

Query: 1111 PWCP 1114
               P
Sbjct: 1309 TNTP 1312



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 76/366 (20%), Positives = 125/366 (34%), Gaps = 23/366 (6%)

Query: 738  SAGFDAARGDPLGG--CQVSPEGYAHLTHLLMG--------LASGRIILILEGGYNLTSI 787
            +AG +  R   +G     VS  G    T  +MG          S       EG    T+ 
Sbjct: 328  AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387

Query: 788  SESMAACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDRE---G 844
            +E   A T S  G     +++     +      +E   V    + +      E  E    
Sbjct: 388  TEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA-STEGSEITIA 446

Query: 845  PSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTPGQTNSETAVVA 904
             +S    T  + + ++        +  K     G    T+++ G E+T   T       A
Sbjct: 447  STSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA 506

Query: 905  LTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILD- 963
             T+   + A +   +   T+S        +  T SE      T  +TT+  T G  +   
Sbjct: 507  STEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTV 566

Query: 964  QTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEAPGGTELIQTPL 1023
             TT  +    +T G  T+  +  G+    T S A  E  T     SE     T   +T  
Sbjct: 567  STTGAETTTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTT 625

Query: 1024 ASSTDHQT-------PPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAPGEENL 1076
            AS+T  +T         T+ V  T  + +  +  GS RT+     S+  + S    E  +
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTV 685

Query: 1077 LGEAAG 1082
              E +G
Sbjct: 686  STEGSG 691



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 61/253 (24%), Positives = 95/253 (37%), Gaps = 20/253 (7%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEESTP-GQTNSETA 901
            EG  ++ + T  +            TT    V  AG    T++  G E+T    T SET 
Sbjct: 959  EGSETTTVTTMGSETTTASTAGSETTT----VSTAGSETTTASIEGSETTTVSSTGSETT 1014

Query: 902  VVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGG-- 959
             V+ T  + +  +T G+    T++ A      +  T SE         +TT+  T G   
Sbjct: 1015 TVSTTGTETTITSTEGSETT-TVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSET 1073

Query: 960  -----AILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGA---TLDQTTSEE 1011
                 A L+ TT   +  G T   T   E          T+ A+ EG+   T+  T+SE 
Sbjct: 1074 TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSET 1133

Query: 1012 APGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGASESQAP 1071
                T   +     +T  +T   S + G+    S +    +  T   GSE+  AS +   
Sbjct: 1134 TTASTTGSEMTTVFTTVSETTTVSTI-GSEATTSSAAGSEATTTSTEGSETTTASTA--- 1189

Query: 1072 GEENLLGEAAGGQ 1084
            G E      AG +
Sbjct: 1190 GSETTTASTAGSE 1202



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 55/235 (23%), Positives = 86/235 (36%), Gaps = 29/235 (12%)

Query: 877  AGMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATL---------AQTISE 926
            AG    T ++ G E+T   T +SET   + T  + +   T G+             T+S 
Sbjct: 140  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVST 199

Query: 927  AAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVG 986
            A      +  T SE         +TT+  T+G     +TT     G  T   T   E   
Sbjct: 200  AGSETTTVSTTGSETTTASTAHSETTAASTMG----SETTKVSTAGSETTVSTAGSETTA 255

Query: 987  GATLAQTTSEAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSP 1036
             +T    T+ A  E +   T   T  E     T   +  +AS+   +T       P T+ 
Sbjct: 256  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315

Query: 1037 VQGTTPQISPSTLIGS--LRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
            V   + +++     GS  +R   +GSE+   S +   G E       G +   DS
Sbjct: 316  VSTASSEVTTVFAAGSETIRASTVGSETTTVSTT---GSETTTASIMGSETSTDS 367



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 58/213 (27%), Positives = 80/213 (37%), Gaps = 15/213 (7%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTN-SETAVVALTQDQPSEAATGGATLAQTISEAAIGGA 932
            V  AG       + G E+T   T  SET  V+ T  + + A+T       T+S +  G  
Sbjct: 1036 VTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT-TVSTSGSGTT 1094

Query: 933  MLGQTTSEEAVGGATPDQTTSEETVGG-AILDQTTSEDAVGGATLGQ------TTSEEAV 985
                  SE      T  +TT+  T G  A    TTS +    +T G       TT  E  
Sbjct: 1095 TASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETT 1154

Query: 986  GGATL---AQTTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTP 1042
              +T+   A T+S A  E  T     SE     T   +T  AS+   +T   S     T 
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETT 1214

Query: 1043 QISPSTLIGSLRTLELGSESQGASESQAPGEEN 1075
              S S   GS       + S+ ++ S A  E N
Sbjct: 1215 TASTS---GSETNTACTTGSETSTPSSAGSETN 1244



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 44/171 (25%), Positives = 71/171 (41%), Gaps = 14/171 (8%)

Query: 884  SASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSE 940
            S    E +T   T+SET +V+ T  + +  +T G+   T++ T SE  +     G TT  
Sbjct: 637  STEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVS 696

Query: 941  EAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAME 1000
                  T  +TT   T G    + TT+       T    T  E    +T    T+ A+ E
Sbjct: 697  -----ITGSETTKVSTTGS---ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTE 748

Query: 1001 GA---TLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPST 1048
            G+   +   T SE     T   +T +AS    +T   S +   T ++S ++
Sbjct: 749  GSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 799



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/224 (24%), Positives = 92/224 (41%), Gaps = 17/224 (7%)

Query: 883  TSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTT 938
            T+ + G E+T   T  SET   +    + + A+T G+   T++ T SE         +TT
Sbjct: 875  TATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETT 934

Query: 939  SEEAVGG-ATPDQTTSEETVG-GAILDQTTSEDAVGG-ATLGQTTSEEAVGGATLAQTTS 995
            +    G   T   TT  ET+   A   +TT+   +G   T   T   E    +T    T+
Sbjct: 935  TASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETT 994

Query: 996  EAAMEGA---TLDQTTSEEAPGGTELIQTPLASSTDHQT-------PPTSPVQGTTPQIS 1045
             A++EG+   T+  T SE     T   +T + S+   +T         T+ V  T  + +
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054

Query: 1046 PSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADS 1089
             ++  GS  T    + S+  + S A  E   +  +  G   A +
Sbjct: 1055 TTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 50/220 (22%), Positives = 80/220 (36%), Gaps = 13/220 (5%)

Query: 874  VLEAGMGKVTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAM 933
            V   G+   T+++ G E T   T         T+   + AA+   +   T+S A      
Sbjct: 546  VSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 605

Query: 934  LGQTTSEEAVGGATPDQTTSEETVGGAILDQTT--SEDAVGGATLGQTTSEEAVGGATLA 991
                 SE      T  +TT+  T        +T  SE      T  +TT     G     
Sbjct: 606  ASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 992  QTT--SEAAMEGATLDQTTSEEAPGGTELI-----QTPLASSTDHQTPPTSPVQGTTPQI 1044
             +T  SE     AT  +TT      GT  +     +T   S+T  +T  TS  +G+  +I
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS-TEGS--EI 722

Query: 1045 SPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQ 1084
            + +++ GS  T    +E    + +   G E       G +
Sbjct: 723  TTASITGS-ETTTASTEGSETTTASTEGSETTSASTTGSE 761



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 51/209 (24%), Positives = 88/209 (42%), Gaps = 15/209 (7%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-NSETAVVALTQDQPSEAATGGA---TLA 921
            TT  +  + + MG  T+  ++ G E+T   T +SE   V     +   A+T G+   T++
Sbjct: 288  TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVS 347

Query: 922  QTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTS 981
             T SE      M  +T+++   G     +TT+  T G      T S +     T+  T S
Sbjct: 348  TTGSETTTASIMGSETSTDSTTGS----ETTTASTEGSE--TTTASTEGSEATTVSTTGS 401

Query: 982  EEAVGGATLAQTTSEA--AMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQG 1039
            E      T ++TT+      E   +  T  E     TE  +  +AS++D +T  T+  +G
Sbjct: 402  ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSET-TTASTEG 460

Query: 1040 TTPQISPSTLIGSLRTLELGSESQGASES 1068
            +      +    +      GSE+  AS +
Sbjct: 461  SETTTVTTAGSETKTAYTTGSETTTASNT 489



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 57/234 (24%), Positives = 90/234 (38%), Gaps = 25/234 (10%)

Query: 843  EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEA------GMGKVTSASFGEE-STPGQ 895
            EG  ++   T+ +       +    TT   +  E       G    T+++ G E +T   
Sbjct: 859  EGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVST 918

Query: 896  TNSETAVVALTQDQPSEAATGGA---TLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTT 952
            T SET   +    + + A+T G+   T++ T SE     A   +TT+   +G     +TT
Sbjct: 919  TGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGS----ETT 974

Query: 953  SEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTSEAAMEGATLDQTTSEEA 1012
            +  T G     +TT+    G  T   T S E     T++ T SE      T  +TT    
Sbjct: 975  TASTAG----SETTTVSTAGSET--TTASIEGSETTTVSSTGSETTTVSTTGTETTITST 1028

Query: 1013 PGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRTLELGSESQGAS 1066
             G      T   S T       S    T+ + S +T + +      GSE+  AS
Sbjct: 1029 EGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST-----TGSETTTAS 1077



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 66/260 (25%), Positives = 101/260 (38%), Gaps = 49/260 (18%)

Query: 868  TTREKKVLEAGMGKVTS--ASFGEESTPGQT-----------NSETAVVALTQDQPSEAA 914
            TT  +  + + MG  T+  ++ G E+T   T           NSET + + T  + +  +
Sbjct: 767  TTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVS 826

Query: 915  TGGATLAQTISEAAIGGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGA 974
            T G+   +TI  A+  G+    TTS E     T     SE T       +TT+   +G  
Sbjct: 827  TAGS---ETIP-ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882

Query: 975  TLGQTTSEEAVGGATLAQTTSEAAMEGA-------------TLDQTTSEEAPGGTELIQT 1021
            T   TT+      +T    T+  + EG+             T+  T SE     TE  +T
Sbjct: 883  T---TTA------STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1022 PLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT--LELGSESQGASESQAPGEENLLGE 1079
              AS+   +    S     T  +S     GS  T    +GSE+  AS +   G E     
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAE---GSETTTVTTMGSETTTASTA---GSETTTVS 987

Query: 1080 AAGGQDMADSMLMQGSRGLT 1099
             AG +    S  ++GS   T
Sbjct: 988  TAGSETTTAS--IEGSETTT 1005



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 24/229 (10%)

Query: 882  VTSASFGEESTPGQTNSETAVVALTQDQPSEAATGGA---TLAQTISEAAI--------- 929
            V  A+    +T   T SET  + +   + + A+T G+   T + T S+  I         
Sbjct: 7    VAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 930  --GGAMLGQTTSEEAVGGATPDQTTSEETVGGAILDQTTSEDAVGGAT--LGQTTSEEAV 985
                A    TT   A  G T       ET       +TT+    G  T  +    SE   
Sbjct: 67   TTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTT 126

Query: 986  GGATLAQT--TSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQ 1043
               T ++T  TS A  E  T+    SE     T   +T  AS+T  +   T+     +  
Sbjct: 127  NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM--TTVFTAGSET 184

Query: 1044 ISPSTLIGSLRTLE-LGSESQGASESQAPGEENLLGEAAGGQDMADSML 1091
            I+PST      T+   GSE+   S +   G E      A  +  A S +
Sbjct: 185  ITPSTAGSETTTVSTAGSETTTVSTT---GSETTTASTAHSETTAASTM 230



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 18/215 (8%)

Query: 878  GMGKVTSASFGEESTPGQT-NSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQ 936
            G G   +++ G E+T   T +SE    +    + + A+T G       SE         +
Sbjct: 580  GSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTG-------SETTTASTTSSE 632

Query: 937  TTSEEAVGGATPD-QTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQTTS 995
            TT+    G  T    TT  ET    ++  T SE  +      +TT+  A G  T   T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETT---MVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689

Query: 996  EAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTPQISPSTLIGSLRT 1055
                  +     T++ +  G+E   T    ST+     T+ + G+  + + ++  GS  T
Sbjct: 690  SGTTTVSITGSETTKVSTTGSETTTT----STEGSEITTASITGS--ETTTASTEGSETT 743

Query: 1056 LELGSESQGASESQAPGEENLLGEAAGGQDMADSM 1090
                  S+  S S    E       +    MA  M
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIM 778


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,672,043
Number of Sequences: 37866
Number of extensions: 2465847
Number of successful extensions: 10817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 160
Number of HSP's that attempted gapping in prelim test: 8751
Number of HSP's gapped (non-prelim): 1105
length of query: 1215
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1101
effective length of database: 13,930,794
effective search space: 15337804194
effective search space used: 15337804194
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.