Guide to the Human Genome
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Name: HDAC8 Sequence: fasta or formatted (377aa) NCBI GI: 8923769
Description:

histone deacetylase 8

Referenced in:

Histones, Related Proteins, and Modifying Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4         28           3
 C cysteine            2.7         10           1
 D aspartate           6.6         25           3
 E glutamate           5.6         21           2
 F phenylalanine       3.4         13           2
 G glycine             8.8         33           4
 H histidine           3.4         13           2
 I isoleucine          6.6         25           1
 K lysine              5.6         21           2
 L leucine             8.5         32           1
 M methionine          2.7         10           1
 N asparagine          2.7         10           1
 P proline             5.0         19           1
 Q glutamine           4.0         15           2
 R arginine            2.9         11           2
 S serine              6.1         23           2
 T threonine           4.5         17           1
 V valine              6.9         26           2
 W tryptophan          1.1          4           1
 Y tyrosine            5.6         21           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   histone deacetylase 8 
HDAC2                 0.393   histone deacetylase 2 
HDAC1                 0.393   histone deacetylase 1 
HDAC3                 0.381   histone deacetylase 3 
HDAC4                 0.109   histone deacetylase 4 
HDAC9                 0.109   histone deacetylase 9 isoform 5 
HDAC9                 0.109   histone deacetylase 9 isoform 1 
HDAC9                 0.109   histone deacetylase 9 isoform 4 
HDAC6                 0.109   histone deacetylase 6 
HDAC5                 0.094   histone deacetylase 5 isoform 3 
HDAC5                 0.094   histone deacetylase 5 isoform 1 
HDAC7                 0.091   histone deacetylase 7 isoform d 
HDAC7                 0.091   histone deacetylase 7 isoform a 
HDAC10                0.089   histone deacetylase 10 isoform 1 
HDAC11                0.065   histone deacetylase 11 isoform 1 
HDAC9                 0.065   histone deacetylase 9 isoform 2 
HDAC11                0.062   histone deacetylase 11 isoform 2 
HDAC10                0.060   histone deacetylase 10 isoform 2 
LOC400696             0.005   hypothetical protein LOC400696 
MYO1B                 0.005   myosin IB isoform 1 
MYO1B                 0.005   myosin IB isoform 2 
MYO1B                 0.005   myosin IB isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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