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Search of human proteins with 4505117
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
(411 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo s... 839 0.0
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 495 e-140
gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens] 399 e-111
gi|226502212 methyl-CpG binding domain protein 3-like [Homo sapi... 134 2e-31
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ... 86 8e-17
gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo s... 86 8e-17
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho... 86 8e-17
gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo ... 86 8e-17
gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo... 86 8e-17
gi|89051034 PREDICTED: methyl-CpG-binding domain protein 3-like ... 79 6e-15
gi|113428063 PREDICTED: similar to methyl-CpG binding domain pro... 79 6e-15
gi|157389003 methyl-CpG binding domain protein 3-like 2 [Homo sa... 79 6e-15
gi|169217724 PREDICTED: similar to methyl-CpG binding domain pro... 79 1e-14
gi|89051032 PREDICTED: methyl-CpG-binding domain protein 3-like ... 79 1e-14
gi|211059437 hypothetical protein LOC284428 [Homo sapiens] 79 1e-14
gi|109452587 family with sequence similarity 98, member B isofor... 75 8e-14
gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens] 74 2e-13
gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens] 74 2e-13
gi|55956899 keratin 9 [Homo sapiens] 69 6e-12
gi|47132620 keratin 2 [Homo sapiens] 67 2e-11
gi|195972866 keratin 10 [Homo sapiens] 66 5e-11
gi|109255251 loricrin [Homo sapiens] 66 5e-11
gi|119395750 keratin 1 [Homo sapiens] 66 7e-11
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 66 7e-11
gi|109148552 keratin 3 [Homo sapiens] 65 1e-10
gi|12056465 fibrillarin [Homo sapiens] 62 7e-10
gi|28875797 small protein rich in arginine and glycine [Homo sap... 62 1e-09
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 58 1e-08
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 58 1e-08
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 57 2e-08
>gi|4505117 methyl-CpG binding domain protein 2 isoform 1 [Homo
sapiens]
Length = 411
Score = 839 bits (2167), Expect = 0.0
Identities = 411/411 (100%), Positives = 411/411 (100%)
Query: 1 MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG
Sbjct: 1 MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
Query: 61 RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG
Sbjct: 61 RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
Query: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180
APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF
Sbjct: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180
Query: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLN 240
SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLN
Sbjct: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLN 240
Query: 241 TTLPIRQTASIFKQPVTKVTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQII 300
TTLPIRQTASIFKQPVTKVTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQII
Sbjct: 241 TTLPIRQTASIFKQPVTKVTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQII 300
Query: 301 KTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCK 360
KTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCK
Sbjct: 301 KTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCK 360
Query: 361 AFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA 411
AFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA
Sbjct: 361 AFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA 411
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 495 bits (1274), Expect = e-140
Identities = 234/234 (100%), Positives = 234/234 (100%)
Query: 1 MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG
Sbjct: 1 MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60
Query: 61 RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG
Sbjct: 61 RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
Query: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180
APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF
Sbjct: 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180
Query: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNK 234
SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNK
Sbjct: 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNK 234
>gi|4505119 methyl-CpG binding domain protein 3 [Homo sapiens]
Length = 291
Score = 399 bits (1026), Expect = e-111
Identities = 190/250 (76%), Positives = 224/250 (89%)
Query: 148 KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFD 207
KR +CPALP GW++EEV R+SGLSAG DV+Y+SPSGKKFRSKPQLARYLG ++DLS+FD
Sbjct: 4 KRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFD 63
Query: 208 FRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKV 267
FRTGKM+ SK+ K++QR+R D NQ KGKPDLNT LP+RQTASIFKQPVTK+TNHPSNKV
Sbjct: 64 FRTGKMLMSKMNKSRQRVRYDSSNQVKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKV 123
Query: 268 KSDPQRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVAS 327
KSDPQ+ +QPRQLFWEK+L GL+A D+ E+++KTM+LPKGLQGVGPG DETLLSA+AS
Sbjct: 124 KSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIAS 183
Query: 328 ALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEAL 387
ALHTS+ PITGQ+SAAVEKNP VWLNT+QPLCKAF+VTDEDIRKQEE VQQVRK+LEEAL
Sbjct: 184 ALHTSTMPITGQLSAAVEKNPGVWLNTTQPLCKAFMVTDEDIRKQEELVQQVRKRLEEAL 243
Query: 388 MADILSRAAD 397
MAD+L+ +
Sbjct: 244 MADMLAHVEE 253
>gi|226502212 methyl-CpG binding domain protein 3-like [Homo
sapiens]
Length = 194
Score = 134 bits (336), Expect = 2e-31
Identities = 76/182 (41%), Positives = 115/182 (63%), Gaps = 2/182 (1%)
Query: 218 LQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKVKSDP-QRMNE 276
+ K+ QR + D +NQ K KP L+T++P+R ++ FK+PVT++T HP N+V+ + E
Sbjct: 1 MAKSSQRKQRDCVNQCKSKPGLSTSIPLRMSSYTFKRPVTRITPHPGNEVRYHQWEESLE 60
Query: 277 QPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASAL-HTSSAP 335
+P+Q+ W++RLQGL A ++ T++L LQ + P +LL +AS L H+ P
Sbjct: 61 KPQQVCWQRRLQGLQAYSSAGELSSTLDLANTLQKLVPSYTGGSLLEDLASGLEHSCPMP 120
Query: 336 ITGQVSAAVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMADILSRA 395
S AVE PA + SQ LCK F+VT+EDIRKQE +V+ VR++L AL+AD L+
Sbjct: 121 HLACSSDAVEIIPAEGVGISQLLCKQFLVTEEDIRKQEGKVKTVRERLAIALIADGLANE 180
Query: 396 AD 397
A+
Sbjct: 181 AE 182
>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
sapiens]
Length = 586
Score = 85.5 bits (210), Expect = 8e-17
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)
Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
+DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+
Sbjct: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
G K P + K++ + P K
Sbjct: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
>gi|7710143 methyl-CpG binding domain protein 1 isoform 4 [Homo
sapiens]
Length = 503
Score = 85.5 bits (210), Expect = 8e-17
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)
Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
+DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+
Sbjct: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
G K P + K++ + P K
Sbjct: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
sapiens]
Length = 556
Score = 85.5 bits (210), Expect = 8e-17
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)
Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
+DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+
Sbjct: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
G K P + K++ + P K
Sbjct: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
>gi|21464117 methyl-CpG binding domain protein 1 isoform 1 [Homo
sapiens]
Length = 605
Score = 85.5 bits (210), Expect = 8e-17
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)
Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
+DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+
Sbjct: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
G K P + K++ + P K
Sbjct: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
>gi|156105673 methyl-CpG binding domain protein 1 isoform 3 [Homo
sapiens]
Length = 549
Score = 85.5 bits (210), Expect = 8e-17
Identities = 42/92 (45%), Positives = 55/92 (59%), Gaps = 7/92 (7%)
Query: 150 MDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFR 209
+DCPAL PGWK+ EV RKSG + G+SD YY SP+G + RSK +L RYLG DL+ FDF+
Sbjct: 6 LDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFK 65
Query: 210 TG-------KMMPSKLQKNKQRLRNDPLNQNK 234
G K P + K++ + P K
Sbjct: 66 QGILCYPAPKAHPVAVASKKRKKPSRPAKTRK 97
>gi|89051034 PREDICTED: methyl-CpG-binding domain protein 3-like
3-like [Homo sapiens]
Length = 208
Score = 79.3 bits (194), Expect = 6e-15
Identities = 60/187 (32%), Positives = 96/187 (51%), Gaps = 7/187 (3%)
Query: 213 MMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKV-KSDP 271
MMP LQK K+ + ++ + + LP+R T+ IF++PVT++ +HP N+V +
Sbjct: 22 MMPWALQK-KREIHMAKAHRRRAA---RSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKG 77
Query: 272 QRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHT 331
E+P+QL +RLQ L + + L L + PG+ E+L A A + +
Sbjct: 78 DEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRS 137
Query: 332 SSAPITGQVSA-AVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMAD 390
P G+ A A P + PL +VT DIR+Q RV++ R++L +AL AD
Sbjct: 138 PLEPTPGRFPAVAGGPTPGMGCQLPPPL-SGQLVTPADIRRQARRVKKARERLAKALQAD 196
Query: 391 ILSRAAD 397
L+R A+
Sbjct: 197 RLARQAE 203
>gi|113428063 PREDICTED: similar to methyl-CpG binding domain
protein 3-like 2 [Homo sapiens]
Length = 204
Score = 79.3 bits (194), Expect = 6e-15
Identities = 60/187 (32%), Positives = 96/187 (51%), Gaps = 7/187 (3%)
Query: 213 MMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKV-KSDP 271
MMP LQK K+ + ++ + + LP+R T+ IF++PVT++ +HP N+V +
Sbjct: 22 MMPWALQK-KREIHMAKAHRRRAA---RSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKG 77
Query: 272 QRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHT 331
E+P+QL +RLQ L + + L L + PG+ E+L A A + +
Sbjct: 78 DEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRS 137
Query: 332 SSAPITGQVSA-AVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMAD 390
P G+ A A P + PL +VT DIR+Q RV++ R++L +AL AD
Sbjct: 138 PLEPTPGRFPAVAGGPTPGMGCQLPPPL-SGQLVTPADIRRQARRVKKARERLAKALQAD 196
Query: 391 ILSRAAD 397
L+R A+
Sbjct: 197 RLARRAE 203
>gi|157389003 methyl-CpG binding domain protein 3-like 2 [Homo
sapiens]
Length = 208
Score = 79.3 bits (194), Expect = 6e-15
Identities = 60/187 (32%), Positives = 96/187 (51%), Gaps = 7/187 (3%)
Query: 213 MMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKV-KSDP 271
MMP LQK K+ + ++ + + LP+R T+ IF++PVT++ +HP N+V +
Sbjct: 22 MMPWALQK-KREIHMAKAHRRRAA---RSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKG 77
Query: 272 QRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHT 331
E+P+QL +RLQ L + + L L + PG+ E+L A A + +
Sbjct: 78 DEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRS 137
Query: 332 SSAPITGQVSA-AVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMAD 390
P G+ A A P + PL +VT DIR+Q RV++ R++L +AL AD
Sbjct: 138 PLEPTPGRFPAVAGGPTPGMGCQLPPPL-SGQLVTPADIRRQARRVKKARERLAKALQAD 196
Query: 391 ILSRAAD 397
L+R A+
Sbjct: 197 RLARRAE 203
>gi|169217724 PREDICTED: similar to methyl-CpG binding domain
protein 3-like 2, partial [Homo sapiens]
Length = 193
Score = 78.6 bits (192), Expect = 1e-14
Identities = 59/187 (31%), Positives = 96/187 (51%), Gaps = 7/187 (3%)
Query: 213 MMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKV-KSDP 271
MMP LQK K+ + ++ + + LP+R T+ IF++PVT++ +HP N+V +
Sbjct: 7 MMPWALQK-KREIHMAKAHRRRAA---RSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKG 62
Query: 272 QRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHT 331
E+P+QL ++LQ L + + L L + PG+ E+L A A + +
Sbjct: 63 DEHLEKPQQLCAYRKLQALQPCSSQGEGSSPLHLESVLSILAPGTASESLDRAGAERVRS 122
Query: 332 SSAPITGQVSA-AVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMAD 390
P G+ A A P + PL +VT DIR+Q RV++ R++L +AL AD
Sbjct: 123 PLEPTPGRFPAVAGGPTPGMGCQLPPPL-SGQLVTPADIRRQARRVKKARERLAKALQAD 181
Query: 391 ILSRAAD 397
L+R A+
Sbjct: 182 RLARRAE 188
>gi|89051032 PREDICTED: methyl-CpG-binding domain protein 3-like
4-like [Homo sapiens]
Length = 208
Score = 78.6 bits (192), Expect = 1e-14
Identities = 60/187 (32%), Positives = 95/187 (50%), Gaps = 7/187 (3%)
Query: 213 MMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKV-KSDP 271
MMP LQK K+ + ++ + + LP+R T+ IF++PVT++ +HP N+V +
Sbjct: 22 MMPWALQK-KREIHMAKAHRRRAA---RSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKG 77
Query: 272 QRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHT 331
E+P+QL +RLQ L + + L L + PG+ E+L A A +
Sbjct: 78 DEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRI 137
Query: 332 SSAPITGQVSA-AVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMAD 390
P G+ A A P + PL +VT DIR+Q RV++ R++L +AL AD
Sbjct: 138 PLEPTPGRFPAVAGGPTPGMGCQLPPPL-SGQLVTPADIRRQARRVKKARERLAKALQAD 196
Query: 391 ILSRAAD 397
L+R A+
Sbjct: 197 RLARQAE 203
>gi|211059437 hypothetical protein LOC284428 [Homo sapiens]
Length = 208
Score = 78.6 bits (192), Expect = 1e-14
Identities = 60/187 (32%), Positives = 95/187 (50%), Gaps = 7/187 (3%)
Query: 213 MMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKV-KSDP 271
MMP LQK K+ + ++ + + LP+R T+ IF++PVT++ +HP N+V +
Sbjct: 22 MMPWALQK-KREIHMAKAHRRRAA---RSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKG 77
Query: 272 QRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHT 331
E+P+QL +RLQ L + + L L + PG+ E+L A A +
Sbjct: 78 DEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRI 137
Query: 332 SSAPITGQVSA-AVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMAD 390
P G+ A A P + PL +VT DIR+Q RV++ R++L +AL AD
Sbjct: 138 PLEPTPGRFPAVAGGPTPGMGCQLPPPL-SGQLVTPADIRRQARRVKKARERLAKALQAD 196
Query: 391 ILSRAAD 397
L+R A+
Sbjct: 197 RLARQAE 203
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 75.5 bits (184), Expect = 8e-14
Identities = 52/119 (43%), Positives = 56/119 (47%), Gaps = 20/119 (16%)
Query: 13 EQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGG-GRGRGRWKQAGRGG 71
+++EG GG G GG GG G G RGG G G G W G GG
Sbjct: 327 KRQEGGGGRGGWGGGGGGGGRGGGGGG-------------GGRGGWGGGGGGWGGGGGGG 373
Query: 72 GVCGRGRGRGRGRGRGRGRGRGRG----RPPSGGSGLGGD--GGGCGGGGSGGGGAPRR 124
G G G G GRG +GRG GRG R GG G G GGG GGGG GGGG RR
Sbjct: 374 GGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432
Score = 65.1 bits (157), Expect = 1e-10
Identities = 44/119 (36%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 33 EQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGR 92
++GG+ + + P P + + GG GRG W G GGG G G G GRG G G G
Sbjct: 307 DRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGW 366
Query: 93 GRGRPPSGGSGLGGDG-----------GGCGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
G G GG G GG G GG GG G GG R P+ G G G G
Sbjct: 367 GGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGG 425
>gi|160707950 methyl CpG binding protein 2 isoform 2 [Homo sapiens]
Length = 498
Score = 73.9 bits (180), Expect = 2e-13
Identities = 53/143 (37%), Positives = 71/143 (49%), Gaps = 15/143 (10%)
Query: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
G G AP P SA P R + G D P LP GW ++ RKSG SAGK D
Sbjct: 79 GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 133
Query: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP-- 229
VY +P GK FRSK +L Y +G+T +D + FDF TG+ PS+ ++ + P
Sbjct: 134 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKA 193
Query: 230 --LNQNKGKP-DLNTTLPIRQTA 249
+ +G+P TT P T+
Sbjct: 194 PGTGRGRGRPKGSGTTRPKAATS 216
>gi|4826830 methyl CpG binding protein 2 isoform 1 [Homo sapiens]
Length = 486
Score = 73.9 bits (180), Expect = 2e-13
Identities = 53/143 (37%), Positives = 71/143 (49%), Gaps = 15/143 (10%)
Query: 117 GGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSD 176
G G AP P SA P R + G D P LP GW ++ RKSG SAGK D
Sbjct: 67 GSGSAPA-----VPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYD 121
Query: 177 VYYFSPSGKKFRSKPQLARY---LGNT-VDLSSFDFR-TGKMMPSKLQKNKQRLRNDP-- 229
VY +P GK FRSK +L Y +G+T +D + FDF TG+ PS+ ++ + P
Sbjct: 122 VYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKA 181
Query: 230 --LNQNKGKP-DLNTTLPIRQTA 249
+ +G+P TT P T+
Sbjct: 182 PGTGRGRGRPKGSGTTRPKAATS 204
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 69.3 bits (168), Expect = 6e-12
Identities = 49/117 (41%), Positives = 51/117 (43%), Gaps = 15/117 (12%)
Query: 7 GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
GG G S GGSG+GG S GG G SG G GGG G
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSG---GGYGGG------SGGGHSGGSGGGHSGG---S 554
Query: 67 AGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGG---SGGGG 120
G GG G G G G G G G G G G GGSG GG+ GG GGG SG GG
Sbjct: 555 GGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG 611
Score = 68.2 bits (165), Expect = 1e-11
Identities = 54/145 (37%), Positives = 58/145 (40%), Gaps = 6/145 (4%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
G G+ G + G G+ G S GG GS SG R G GG G G
Sbjct: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSR--GGSGGSYGGGSGS 526
Query: 66 QAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGS---GGGGAP 122
G GGG G G G G G G G G G GGSG GG GG GGGS GG G
Sbjct: 527 GGGSGGGY-GGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGS 585
Query: 123 RREPVPFPSGSAGPGPRGPRATESG 147
F S G G A+ SG
Sbjct: 586 HGGGSGFGGESGGSYGGGEEASGSG 610
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/123 (39%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Query: 17 GESAAGGSGAG-GDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRG-GGVC 74
G GGSG G G + +GG G + SG G GGG G G +G G G
Sbjct: 495 GSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGS 554
Query: 75 GRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSA 134
G G G G G G G G G G GGSG G GGG G GG GG E G
Sbjct: 555 GGNYGGGSGSGGGSGGGYGGGSGSRGGSG-GSHGGGSGFGGESGGSYGGGEEASGSGGGY 613
Query: 135 GPG 137
G G
Sbjct: 614 GGG 616
Score = 63.9 bits (154), Expect = 2e-10
Identities = 53/140 (37%), Positives = 58/140 (41%), Gaps = 23/140 (16%)
Query: 14 QEEGESAAGGS-GAGGDSAIEQGGQGSALAPSPVSGVRRE---GARGGGRGRGRWKQAGR 69
QE+ ES+ G G GG +GG G + G G GGG G G + G
Sbjct: 462 QEDFESSGAGKIGLGG-----RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGS 516
Query: 70 GGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCG--GGGSGGGGAPRREPV 127
GG G G G G G G G G G G SGGSG G GG G GGGSG GG
Sbjct: 517 GGSY---GGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGG------ 567
Query: 128 PFPSGSAGPGPRGPRATESG 147
SG G G R G
Sbjct: 568 ---SGGGYGGGSGSRGGSGG 584
Score = 62.4 bits (150), Expect = 7e-10
Identities = 49/144 (34%), Positives = 51/144 (35%), Gaps = 2/144 (1%)
Query: 7 GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
GGR G + GGSG GG G SG G G G G G
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYG 535
Query: 67 AGRGGGVCG-RGRGRGRGRGRGRGRGRGRGRPPSGGSGLG-GDGGGCGGGGSGGGGAPRR 124
G GGG G G G G G G G G G GG G G G GG GG GG G
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGE 595
Query: 125 EPVPFPSGSAGPGPRGPRATESGK 148
+ G G G SGK
Sbjct: 596 SGGSYGGGEEASGSGGGYGGGSGK 619
Score = 58.9 bits (141), Expect = 8e-09
Identities = 43/104 (41%), Positives = 47/104 (45%), Gaps = 11/104 (10%)
Query: 19 SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGR 78
S++GG G GG + G G G R RGGG G G GGG
Sbjct: 36 SSSGGGGGGGRFSSSSGYGG---------GSSRVCGRGGGGSFGYSYGGGSGGGFSASSL 86
Query: 79 GRGRGRG-RGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
G G G G RG G G G SGG G GG GGG GGG GG G+
Sbjct: 87 GGGFGGGSRGFGGASGGGYSSSGGFG-GGFGGGSGGGFGGGYGS 129
Score = 56.2 bits (134), Expect = 5e-08
Identities = 44/118 (37%), Positives = 49/118 (41%), Gaps = 16/118 (13%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQ---GGQGSALAPSPVSGVRREGARGGGRGRG 62
GGGR G ++ G GG + GG G + S + G G GG RG G
Sbjct: 43 GGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGG----GFGGGSRGFG 98
Query: 63 RWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
G GG G G G G G G G G G GSG GG GG GG G G GG
Sbjct: 99 -----GASGGGYSSSGGFGGGFGGGSGGGFGGGY----GSGFGGFGGFGGGAGGGDGG 147
Score = 53.9 bits (128), Expect = 3e-07
Identities = 42/102 (41%), Positives = 47/102 (46%), Gaps = 16/102 (15%)
Query: 24 SGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA-GRGGG---VCGRGRG 79
SG GG + GG S S R + GGG G GR+ + G GGG VCGRG G
Sbjct: 14 SGGGGGGGLGSGG-------SIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 80 RGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGG-GGSGGGG 120
G G G G G GG G GGG G GG+ GGG
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGG----GFGGGSRGFGGASGGG 104
Score = 46.2 bits (108), Expect = 5e-05
Identities = 39/114 (34%), Positives = 42/114 (36%), Gaps = 21/114 (18%)
Query: 27 GGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGR 86
GG E G G G+ G GG GRG + G GG G G G G G G
Sbjct: 460 GGQEDFESSGAGKI-------GLGGRGGSGGSYGRG--SRGGSGGSYGGGGSGGGYGGGS 510
Query: 87 GRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
G RG G GG GG G G G GG SG +G G G
Sbjct: 511 G-----SRG-------GSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/85 (36%), Positives = 35/85 (41%), Gaps = 9/85 (10%)
Query: 4 HPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGR 63
H GG G + GGSG+GG S GG G SG G+ GGG G G
Sbjct: 542 HSGGSGGGHSGGSGGNYGGGSGSGGGSG---GGYGGGSGSRGGSG----GSHGGGSGFGG 594
Query: 64 WKQAGRGGG--VCGRGRGRGRGRGR 86
GGG G G G G G G+
Sbjct: 595 ESGGSYGGGEEASGSGGGYGGGSGK 619
Score = 29.6 bits (65), Expect = 5.2
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Query: 102 SGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
S L GGG GGGG G GG+ R F S S G G G ++ SG
Sbjct: 9 SYLSRSGGG-GGGGLGSGGSIRSSYSRF-SSSGGGGGGGRFSSSSG 52
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 67.4 bits (163), Expect = 2e-11
Identities = 47/109 (43%), Positives = 56/109 (51%), Gaps = 9/109 (8%)
Query: 18 ESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRG-----GG 72
++A GGSG G S+ GG S+ + S SG R+ G+RGG G G G G GG
Sbjct: 515 KAAFGGSGGRGSSS---GGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGG 571
Query: 73 VCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
G G G G G G G G G+ SGG GG G GG GSGGGG+
Sbjct: 572 RYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG-GGYGSGGGGS 619
Score = 58.2 bits (139), Expect = 1e-08
Identities = 55/150 (36%), Positives = 60/150 (40%), Gaps = 20/150 (13%)
Query: 11 CPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ---A 67
C + G G G SA+ GG S + S S + R G GGG G G +
Sbjct: 7 CKSRGRGGGGGGFRGFSSGSAVVSGG--SRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLV 64
Query: 68 GRGG------GVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGG-GSGGGG 120
G GG V G G G G G G GRG G G GGS GG G GGG G GG G
Sbjct: 65 GLGGTKSISISVAGGGGGFGAAGGFG-GRGGGFG----GGSSFGGGSGFSGGGFGGGGFG 119
Query: 121 APRREPVPFP---SGSAGPGPRGPRATESG 147
R P G GPG GP G
Sbjct: 120 GGRFGGFGGPGGVGGLGGPGGFGPGGYPGG 149
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/111 (40%), Positives = 49/111 (44%), Gaps = 5/111 (4%)
Query: 10 CCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGG--GRGRGRWKQA 67
C G GG G G S + GG S ++ S G GA GG GRG G +
Sbjct: 42 CLSRHGGGGGGFGGGGFGSRSLVGLGGTKS-ISISVAGGGGGFGAAGGFGGRGGGFGGGS 100
Query: 68 GRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGG 118
GGG G G G G G G GR G G P G GLGG GG GG GG
Sbjct: 101 SFGGGSGFSGGGFGGG-GFGGGRFGGFGGP-GGVGGLGGPGGFGPGGYPGG 149
Score = 46.6 bits (109), Expect = 4e-05
Identities = 37/111 (33%), Positives = 41/111 (36%), Gaps = 19/111 (17%)
Query: 47 SGVRREGARGGGRGRGRWKQAGRGGGVC----------GRGRGRGRGRGRGRGRGRGRGR 96
S V + A GG GRG G G RG G G G G G G G
Sbjct: 510 SNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGS 569
Query: 97 PPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
GSG G GG GGG G GG S+G G RG ++ G
Sbjct: 570 GGRYGSGGGSKGGSISGGGYGSGGGKH---------SSGGGSRGGSSSGGG 611
Score = 45.8 bits (107), Expect = 7e-05
Identities = 33/101 (32%), Positives = 39/101 (38%), Gaps = 16/101 (15%)
Query: 17 GESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGR 76
G + G+GG +I GG GS G R G G +GG + G
Sbjct: 543 GRQSGSRGGSGGGGSISGGGYGSGGG---------SGGRYGSGG------GSKGGSISGG 587
Query: 77 GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSG 117
G G G G+ G RG G GG G GG G G SG
Sbjct: 588 GYGSGGGKHSSGGGSRG-GSSSGGGYGSGGGGSSSVKGSSG 627
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 66.2 bits (160), Expect = 5e-11
Identities = 50/133 (37%), Positives = 56/133 (42%), Gaps = 9/133 (6%)
Query: 16 EGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCG 75
EGE ++GG G GG S GG G + SG G GG G G + GGG G
Sbjct: 454 EGEGSSGGGGRGGGSF--GGGYGGGSSGGGSSGGGHGGGHGGSSGGG-YGGGSSGGGSSG 510
Query: 76 RGRGRGR---GRGRGRGRGRGRGRPPSGGSGLG--GDGGGCGGGGSGGGGAPRREPVPFP 130
G G G G G G G G GG G G GGG GG GGG+
Sbjct: 511 GGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSS 570
Query: 131 SGSAG-PGPRGPR 142
SGS G +GPR
Sbjct: 571 SGSVGESSSKGPR 583
Score = 57.0 bits (136), Expect = 3e-08
Identities = 46/122 (37%), Positives = 51/122 (41%), Gaps = 12/122 (9%)
Query: 19 SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGR 78
S +GG G GG GG S+L S G G GG G + + GGG G
Sbjct: 14 SRSGGGGGGGGCG--GGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSS 71
Query: 79 GRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGP 138
G G G G G G R G S GG GG GGGS GGG+ F GS G G
Sbjct: 72 GGYGGLG---GFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGS-------FGGGSFGGGG 121
Query: 139 RG 140
G
Sbjct: 122 FG 123
Score = 49.3 bits (116), Expect = 6e-06
Identities = 37/104 (35%), Positives = 42/104 (40%), Gaps = 7/104 (6%)
Query: 19 SAAGGSGAGGDS--AIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGR 76
S GG +GG S + +G G G G GGG RG + + GG
Sbjct: 42 SLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSY--- 98
Query: 77 GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
G G G G G G GG G GG GGG GGG G GG
Sbjct: 99 --GGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGG 140
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 66.2 bits (160), Expect = 5e-11
Identities = 53/143 (37%), Positives = 58/143 (40%), Gaps = 17/143 (11%)
Query: 11 CPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRG 70
C + G GGSG GG GG G + S G GGG G G G G
Sbjct: 16 CVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGS-SGGGGG 74
Query: 71 GGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGL---GGDGGGC---GGGGSGGGGAPRR 124
GG+ G G G G G + G G GGSG GG G GC GGGGS GGG+
Sbjct: 75 GGIGGCGGGSG-----GSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG-- 127
Query: 125 EPVPFPSGSAGPGPRGPRATESG 147
F SG G G SG
Sbjct: 128 ---CFSSGGGGSSGGGSGCFSSG 147
Score = 63.9 bits (154), Expect = 2e-10
Identities = 63/197 (31%), Positives = 69/197 (35%), Gaps = 57/197 (28%)
Query: 6 GGGRCCPEQEEGESAAGGSG----------AGGDSAIEQGG---QGSALAPSPVSGVRRE 52
GGG C G S+ GGSG GG GG G A+ GV
Sbjct: 108 GGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSG 167
Query: 53 GARGGGRGRGRWKQAGRGGGVCG-RGRGRGRGRGRGRGRGRG-----------------R 94
G+ GG G G + G GG VCG G G G G G G G G
Sbjct: 168 GSSGG--GSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSY 225
Query: 95 GRPPSGGSGLGGDG----------GGCGGGGSG--------GGGAPRREPVPFPSGSAGP 136
G SGG G GG G GCGGG SG GGG+ GS+G
Sbjct: 226 GGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGS------VCGGGSSGG 279
Query: 137 GPRGPRATESGKRMDCP 153
G G SG P
Sbjct: 280 GGGGSSVGGSGSGKGVP 296
Score = 56.2 bits (134), Expect = 5e-08
Identities = 42/101 (41%), Positives = 44/101 (43%), Gaps = 9/101 (8%)
Query: 45 PVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGL 104
PV V+ G GGG G G GGG G G G G G G G G G SG
Sbjct: 13 PVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSS-GSGCGYSGGGGYSGGGCGGGSSGG 71
Query: 105 GGDG--GGCGGGG------SGGGGAPRREPVPFPSGSAGPG 137
GG G GGCGGG SGGGG+ F SG G G
Sbjct: 72 GGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSG 112
Score = 55.8 bits (133), Expect = 7e-08
Identities = 50/147 (34%), Positives = 57/147 (38%), Gaps = 26/147 (17%)
Query: 19 SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGAR------GGGRGRGRWKQAGRGGG 72
S GGS GG GG GS S G G+ GG G G + GGG
Sbjct: 91 SGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGG 150
Query: 73 VCGRG---RGRGRGRGRGRGRGRGRGRPPSGGSG-----LGGDGGGCGGGGSGGGGA--- 121
G+ + G G G G G G SGG G G G GCGGG SGG G+
Sbjct: 151 FSGQAVQCQSYG-GVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYV 209
Query: 122 -----PRREPVPFPS---GSAGPGPRG 140
+ P PS GS+G G G
Sbjct: 210 SSQQVTQTSCAPQPSYGGGSSGGGGSG 236
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/117 (35%), Positives = 46/117 (39%), Gaps = 26/117 (22%)
Query: 8 GRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA 67
G C G + GG G G GG G + G GGG G G K +
Sbjct: 48 GSGCGYSGGGGYSGGGCGGGSSG----GGGGGGI-----------GGCGGGSG-GSVKYS 91
Query: 68 GRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGC---GGGGSGGGGA 121
G GG G G G G G G SGG G G G GC GGGGS GGG+
Sbjct: 92 GGGG-------SSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGS 141
Score = 29.6 bits (65), Expect = 5.2
Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 7/52 (13%)
Query: 96 RPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
+PP G GGG GG G GG G F G +G G G SG
Sbjct: 11 QPPVDCVKTSGGGGGGGGSGGGGCGF-------FGGGGSGGGSSGSGCGYSG 55
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 65.9 bits (159), Expect = 7e-11
Identities = 51/121 (42%), Positives = 54/121 (44%), Gaps = 13/121 (10%)
Query: 2 RAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGR 61
R+ GGGR G S G G G S + GG S + ARGGGRG
Sbjct: 38 RSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKS---------ISISVARGGGRGS 88
Query: 62 GRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
G G GGG G G G G G G G G G SGG G G GGG GGGG GGG
Sbjct: 89 GFG--GGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFG--GGGFGGGGYGGGYG 144
Query: 122 P 122
P
Sbjct: 145 P 145
Score = 58.5 bits (140), Expect = 1e-08
Identities = 45/124 (36%), Positives = 49/124 (39%), Gaps = 16/124 (12%)
Query: 8 GRCCPEQEEGESAA------GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGR 61
G C P S + GGS GG GG GS + G GGG GR
Sbjct: 495 GECAPNVSVSVSTSHTTISGGGSRGGGG-----GGYGSGGSSYGSGGGSYGSGGGGGGGR 549
Query: 62 GRWKQAGR----GGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSG 117
G + G GGG G G G G G G G R SGG G GG GG G GG
Sbjct: 550 GSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGG-GGSSGGRGSGGGS 608
Query: 118 GGGA 121
GG+
Sbjct: 609 SGGS 612
Score = 58.2 bits (139), Expect = 1e-08
Identities = 39/100 (39%), Positives = 41/100 (41%), Gaps = 1/100 (1%)
Query: 22 GGSGAGGDSAIEQGGQ-GSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGR 80
GG G+GG S GG GS G G G G G + G GGG G G
Sbjct: 523 GGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGS 582
Query: 81 GRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
G RG G G G GSG G GG GG GS GG
Sbjct: 583 SSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 11/105 (10%)
Query: 17 GESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGR 76
G +GG G GG + GG SG G+ GGG G G + GG G
Sbjct: 537 GSYGSGGGGGGGRGSYGSGGSSYG------SGGGSYGSGGGGGGHGSYGSGSSSGGYRGG 590
Query: 77 GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGA 121
G G G GRG G G S G +GG G GG S GG +
Sbjct: 591 SGGGGGGSSGGRGSGGG-----SSGGSIGGRGSSSGGVKSSGGSS 630
Score = 56.6 bits (135), Expect = 4e-08
Identities = 59/176 (33%), Positives = 67/176 (38%), Gaps = 47/176 (26%)
Query: 19 SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRG- 77
S+ G +GG + G + + S RR G GGG GR+ G GGG G G
Sbjct: 6 SSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSG--GGG---GRFSSCGGGGGSFGAGG 60
Query: 78 ---------------------RGRGRGRGRGRGRGRGR-GRPPSGGSGLGG---DGGGCG 112
RG GRG G G G G G G GG G GG GGG G
Sbjct: 61 GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120
Query: 113 GGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKS 168
G GSGGGG F G G G G P PPG +E I +S
Sbjct: 121 GFGSGGGG--------FGGGGFGGGGYGGGYG--------PVCPPGGIQEVTINQS 160
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/115 (38%), Positives = 48/115 (41%), Gaps = 18/115 (15%)
Query: 46 VSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGR----GRGRGRGRGRPPSGG 101
+SG G GGG G G G GGG G G G G GRG G G G G SGG
Sbjct: 512 ISGGGSRGGGGGGYGSGG-SSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGG 570
Query: 102 SGLG----GDGGGCGG-----GGSGGGGAPRREPVPFPSGSAGPGPRGPRATESG 147
G G G G GG GG GGG + R G + G G R + SG
Sbjct: 571 GGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRG----SGGGSSGGSIGGRGSSSG 621
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/161 (34%), Positives = 68/161 (42%), Gaps = 21/161 (13%)
Query: 7 GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
GG P G GSG GG + QG + + SG +G+RGG G+
Sbjct: 484 GGDYMPMNNWGSGNGRGSG-GGQGSNGQGSSSHSSGGNQCSG-EGQGSRGGQGSNGQ--- 538
Query: 67 AGRGGGVCGR-GRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRRE 125
G GG C R G+G G G G G+ G G GG G GDG G GGG + GGG
Sbjct: 539 -GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQG-PGDGHGSGGGKNSGGGKGSGS 596
Query: 126 PVPFPSGSAGPGPRGP---------RATESGKRMDCPALPP 157
GS G G RG + T+S ++ P PP
Sbjct: 597 ----GKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPP 633
Score = 60.8 bits (146), Expect = 2e-09
Identities = 66/253 (26%), Positives = 100/253 (39%), Gaps = 35/253 (13%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREG-ARGGGRGRGRW 64
GGG+ Q ++GG+ G+ +GGQGS S + R+G GG G G
Sbjct: 502 GGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGG 561
Query: 65 KQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGG--------- 115
++ G G G G G+G G G G G G+ G G+ GSG G DG G G
Sbjct: 562 QRPGGGHG-SGGGQGPGDGHGSGGGKNSGGGK--GSGSGKGSDGDGERGKSLKKRSYFGK 618
Query: 116 ---SGGGGAPRREPVPFP----SGSAGPGPRGPR-----ATESGKRMDCPALPPGWKKEE 163
S P P P P G+ G G G R + G +C K+ +
Sbjct: 619 LTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKEC-------KEAK 671
Query: 164 VIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDL-SSFDFRTGKMMPSKLQKNK 222
++ + + G + + + + + P + G L SS D+ M P + +K
Sbjct: 672 EVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYM--PMAPQNVSASK 729
Query: 223 QRLRNDPLNQNKG 235
+R P ++G
Sbjct: 730 KRHSRSPFEDSRG 742
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 64.7 bits (156), Expect = 1e-10
Identities = 54/149 (36%), Positives = 62/149 (41%), Gaps = 16/149 (10%)
Query: 3 AHPGGGRCCPEQEEGESAAG---GSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGR 59
AH GG G A G G+G G ++ G +++ S +G G+R GG
Sbjct: 33 AHSGGA--------GGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAG----GSRAGGF 80
Query: 60 GRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGG- 118
G GR A GG G G G G G G G G GRG G G G GG GG G GG GG
Sbjct: 81 GGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGP 140
Query: 119 GGAPRREPVPFPSGSAGPGPRGPRATESG 147
GG P PG GP G
Sbjct: 141 GGFGGSGGFGGPGSLGSPGGFGPGGFPGG 169
Score = 48.5 bits (114), Expect = 1e-05
Identities = 35/82 (42%), Positives = 40/82 (48%), Gaps = 12/82 (14%)
Query: 39 SALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPP 98
SA++ S VS + GG G G GGG+ G G G G G G G G GRG
Sbjct: 519 SAVSISVVSSSTTSASAGGYGG-------GYGGGM-GGGLGGGFSAGGGSGSGFGRG--- 567
Query: 99 SGGSGLGGDGGGCGGGGSGGGG 120
GG G+GG GG G SGG G
Sbjct: 568 -GGGGIGGGFGGGSSGFSGGSG 588
Score = 42.4 bits (98), Expect = 8e-04
Identities = 32/69 (46%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 53 GARGGGRGRGRWKQAGRG---GGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGG 109
G GGG G G G G GG G G GRG G G G G G G SGGSG G G
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFG-GGSSGFSGGSGFGSISG 594
Query: 110 ---GCGGGG 115
G GGG
Sbjct: 595 ARYGVSGGG 603
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/71 (45%), Positives = 33/71 (46%), Gaps = 8/71 (11%)
Query: 79 GRGRGRGRGRGRGRGRGRPPSGGSGLG-GDGGGCG-GGGSGGGGAPRREPVPFPSGSAGP 136
G G G G G G G G G GGSG G G GGG G GGG GGG + F GS
Sbjct: 537 GYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSS------GFSGGSGFG 590
Query: 137 GPRGPRATESG 147
G R SG
Sbjct: 591 SISGARYGVSG 601
Score = 34.3 bits (77), Expect = 0.21
Identities = 30/91 (32%), Positives = 32/91 (35%), Gaps = 6/91 (6%)
Query: 19 SAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGR 78
S+ + AGG GG G L G G G G GRG G GGG G
Sbjct: 528 SSTTSASAGGYGGGYGGGMGGGLG----GGFSAGGGSGSGFGRGGG--GGIGGGFGGGSS 581
Query: 79 GRGRGRGRGRGRGRGRGRPPSGGSGLGGDGG 109
G G G G G G G S GG
Sbjct: 582 GFSGGSGFGSISGARYGVSGGGFSSASNRGG 612
Score = 33.9 bits (76), Expect = 0.28
Identities = 29/85 (34%), Positives = 33/85 (38%), Gaps = 8/85 (9%)
Query: 35 GGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGR 94
GG G G+ + GGG G G GRGG G G G G G G G G
Sbjct: 536 GGYGGGYGGGMGGGLGGGFSAGGGSGSG----FGRGG---GGGIGGGFG-GGSSGFSGGS 587
Query: 95 GRPPSGGSGLGGDGGGCGGGGSGGG 119
G G+ G GGG + GG
Sbjct: 588 GFGSISGARYGVSGGGFSSASNRGG 612
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 62.4 bits (150), Expect = 7e-10
Identities = 44/98 (44%), Positives = 48/98 (48%), Gaps = 21/98 (21%)
Query: 55 RGGG-RGRGRWKQAGRGGGVCGRGRGRGRGRG-RGRGRGRGRGRPPSGGSGLGGDGGGCG 112
RGGG GRG + G GG G G GRGRG G RGRGRG GG GGG G
Sbjct: 8 RGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRG-------------GGGGGGGG 54
Query: 113 GGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRM 150
GGG GGG G+ G G G R +SGK +
Sbjct: 55 GGGGRGGGGFH------SGGNRGRGRGGKRGNQSGKNV 86
Score = 47.4 bits (111), Expect = 2e-05
Identities = 31/73 (42%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 22 GGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRG 81
GG G GD +GG+G G R RGGG G G GRGGG G RG
Sbjct: 13 GGRGGFGDRG-GRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRG 71
Query: 82 RGRGRGRGRGRGR 94
RGRG RG G+
Sbjct: 72 RGRGGKRGNQSGK 84
Score = 33.1 bits (74), Expect = 0.47
Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 10/64 (15%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
GGGR G GG G GG GG+G G G RG GRG R
Sbjct: 31 GGGRGRGGGFRGRGRGGGGGGGGGGG---GGRGG-------GGFHSGGNRGRGRGGKRGN 80
Query: 66 QAGR 69
Q+G+
Sbjct: 81 QSGK 84
>gi|28875797 small protein rich in arginine and glycine [Homo
sapiens]
Length = 248
Score = 61.6 bits (148), Expect = 1e-09
Identities = 44/103 (42%), Positives = 51/103 (49%), Gaps = 13/103 (12%)
Query: 7 GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQG--------SALAPSPVSGVRREGARG-G 57
GGR P + G G G + +GG A +P G+RR G RG G
Sbjct: 101 GGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRRGGVRGRG 160
Query: 58 GRGRGRWKQAGRG-GGVCGRGRG---RGRGRGRGRGRGRGRGR 96
G GRG + G GG+ GRGRG RGRG GRGRGRGRGR
Sbjct: 161 GPGRGGLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGRGRGRGR 203
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/106 (38%), Positives = 46/106 (43%), Gaps = 14/106 (13%)
Query: 31 AIEQGGQGSALAPSPVSGVRREGARGGGRGRG--------RWKQAGRGGGVC----GRGR 78
A+ +G G P G+ R G RGG R R + RGG G R
Sbjct: 94 ALARGAIGGRGLPIIQRGLPRGGLRGGRATRTLLRGGMSLRGQNLLRGGRAVAPRMGLRR 153
Query: 79 GRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRR 124
G RGRG G GRG G GR G G+GG G G G G GG G R
Sbjct: 154 GGVRGRG-GPGRG-GLGRGAMGRGGIGGRGRGMIGRGRGGFGGRGR 197
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/119 (36%), Positives = 49/119 (41%), Gaps = 9/119 (7%)
Query: 12 PEQEEGESAAG---GSGAGGDSAIE-QGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA 67
P E+ + G G G GG+ +GG+G G R G GG R G
Sbjct: 379 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG--YGGDRSGGGYGGDRSSGGGYSG 436
Query: 68 GRGGGVCG---RGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPR 123
R GG G G G G RG G G RG G G G GGD GG GG GG G R
Sbjct: 437 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDR 495
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/149 (37%), Positives = 58/149 (38%), Gaps = 12/149 (8%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQ--GSALAPSPVSGVRREGARGGGRGRGR 63
GGG G G G GGD GG G G R G GG RG
Sbjct: 440 GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 499
Query: 64 WKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGD-GGGCGGGGSGGGGAP 122
+ G GG G G RG G G R RG G G GGSG GGD GG GG SGGG
Sbjct: 500 GDRGGYGGDRGGYGGDRG-GYGGDRSRG-GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 557
Query: 123 RREPVPFPSGSAGPGPRGPRATESGKRMD 151
R G G RG + G R D
Sbjct: 558 DR-------GGGYGGDRGGYGGKMGGRND 579
Score = 55.5 bits (132), Expect = 9e-08
Identities = 48/120 (40%), Positives = 51/120 (42%), Gaps = 10/120 (8%)
Query: 7 GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
GGR G +GG G GGD + GG + G R G GG RG G
Sbjct: 406 GGRGGDRGGYGGDRSGG-GYGGDRS-SGGGYSGDRSGGGYGGDRSGGGYGGDRGGG--YG 461
Query: 67 AGRGGGVCG-RGRGRGRGRG-----RGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
RGGG G RG G G RG RG G G RG G GGD GG GG G GG
Sbjct: 462 GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGG 521
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/108 (38%), Positives = 43/108 (39%), Gaps = 9/108 (8%)
Query: 45 PVSGVRREGARGGGRG-RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSG 103
P G R GG RG RGR + G GG G G G G R G G R G G
Sbjct: 386 PSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR---SGGG 442
Query: 104 LGGD--GGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
GGD GGG GG GG G R G G G G R G R
Sbjct: 443 YGGDRSGGGYGGDRGGGYGGDRGGGY---GGDRGGGYGGDRGGYGGDR 487
Score = 47.4 bits (111), Expect = 2e-05
Identities = 42/112 (37%), Positives = 42/112 (37%), Gaps = 20/112 (17%)
Query: 48 GVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRG-----RGRGRGRGRPPSG-- 100
G R G RGG RG G GG G G G R G G G G G R G
Sbjct: 401 GYRGRGGRGGDRG-------GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG 453
Query: 101 ---GSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
G G GGD GG GG GGG R G G G G R G R
Sbjct: 454 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGY---GGDRGGGYGGDRGGYGGDR 502
Score = 42.7 bits (99), Expect = 6e-04
Identities = 55/150 (36%), Positives = 58/150 (38%), Gaps = 35/150 (23%)
Query: 6 GGGRCCPEQEEGESAAGG-SGAGGDSAIEQGGQGSALAPSPVSG----VRREGARGGGRG 60
GGGR G GG G GGD G + P+P G RR
Sbjct: 328 GGGR---RGRGGYRGRGGFQGRGGDPK-----SGDWVCPNPSCGNMNFARRNSCNQCNEP 379
Query: 61 RGRWKQAGRGGGVCGRGRGRGRGRGRG-RGRGRGRGRPPSG------GSGLGGD---GGG 110
R + R G G RGRG G RG RGRG GRG G G G GGD GGG
Sbjct: 380 R---PEDSRPSG--GDFRGRGYGGERGYRGRG-GRGGDRGGYGGDRSGGGYGGDRSSGGG 433
Query: 111 CGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
G SGGG R SG G RG
Sbjct: 434 YSGDRSGGGYGGDR------SGGGYGGDRG 457
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/126 (30%), Positives = 41/126 (32%), Gaps = 51/126 (40%)
Query: 69 RGGGVCGRGRGRGRGRGRG----------------------------------------- 87
RGGG G RGRG RGRG
Sbjct: 323 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 382
Query: 88 ---------RGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGG-GAPRREPVPFPSGSAGPG 137
RGRG G R G G GGD GG GG SGGG G R + +G G
Sbjct: 383 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 442
Query: 138 PRGPRA 143
G R+
Sbjct: 443 YGGDRS 448
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/54 (42%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 72 GVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRRE 125
G RG G +G GRGRG GR P GS GGD GG G PR +
Sbjct: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSS-GGDRGGFKNFGGHRDYGPRTD 220
Score = 34.7 bits (78), Expect = 0.16
Identities = 32/93 (34%), Positives = 37/93 (39%), Gaps = 4/93 (4%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
GG R + G G GGD + +GG G G R G GG R G +
Sbjct: 499 GGDRGGYGGDRGGYGGDRGGYGGDRS--RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY- 555
Query: 66 QAGRGGGVCG-RGRGRGRGRGRGRGRGRGRGRP 97
RGGG G RG G+ GR R R RP
Sbjct: 556 GGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRP 588
Score = 32.3 bits (72), Expect = 0.80
Identities = 17/41 (41%), Positives = 22/41 (53%)
Query: 53 GARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRG 93
G++GGGRGRG + + GRG G RG + G R G
Sbjct: 176 GSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 216
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 58.2 bits (139), Expect = 1e-08
Identities = 44/119 (36%), Positives = 49/119 (41%), Gaps = 9/119 (7%)
Query: 12 PEQEEGESAAG---GSGAGGDSAIE-QGGQGSALAPSPVSGVRREGARGGGRGRGRWKQA 67
P E+ + G G G GG+ +GG+G G R G GG R G
Sbjct: 382 PRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGG--YGGDRSGGGYGGDRSSGGGYSG 439
Query: 68 GRGGGVCG---RGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPR 123
R GG G G G G RG G G RG G G G GGD GG GG GG G R
Sbjct: 440 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDR 498
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/149 (37%), Positives = 58/149 (38%), Gaps = 12/149 (8%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQ--GSALAPSPVSGVRREGARGGGRGRGR 63
GGG G G G GGD GG G G R G GG RG
Sbjct: 443 GGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYG 502
Query: 64 WKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGD-GGGCGGGGSGGGGAP 122
+ G GG G G RG G G R RG G G GGSG GGD GG GG SGGG
Sbjct: 503 GDRGGYGGDRGGYGGDRG-GYGGDRSRG-GYGGDRGGGSGYGGDRSGGYGGDRSGGGYGG 560
Query: 123 RREPVPFPSGSAGPGPRGPRATESGKRMD 151
R G G RG + G R D
Sbjct: 561 DR-------GGGYGGDRGGYGGKMGGRND 582
Score = 55.5 bits (132), Expect = 9e-08
Identities = 48/120 (40%), Positives = 51/120 (42%), Gaps = 10/120 (8%)
Query: 7 GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
GGR G +GG G GGD + GG + G R G GG RG G
Sbjct: 409 GGRGGDRGGYGGDRSGG-GYGGDRS-SGGGYSGDRSGGGYGGDRSGGGYGGDRGGG--YG 464
Query: 67 AGRGGGVCG-RGRGRGRGRG-----RGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120
RGGG G RG G G RG RG G G RG G GGD GG GG G GG
Sbjct: 465 GDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGG 524
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/108 (38%), Positives = 43/108 (39%), Gaps = 9/108 (8%)
Query: 45 PVSGVRREGARGGGRG-RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSG 103
P G R GG RG RGR + G GG G G G G R G G R G G
Sbjct: 389 PSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDR---SGGG 445
Query: 104 LGGD--GGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
GGD GGG GG GG G R G G G G R G R
Sbjct: 446 YGGDRSGGGYGGDRGGGYGGDRGGGY---GGDRGGGYGGDRGGYGGDR 490
Score = 47.4 bits (111), Expect = 2e-05
Identities = 42/112 (37%), Positives = 42/112 (37%), Gaps = 20/112 (17%)
Query: 48 GVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRG-----RGRGRGRGRPPSG-- 100
G R G RGG RG G GG G G G R G G G G G R G
Sbjct: 404 GYRGRGGRGGDRG-------GYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYG 456
Query: 101 ---GSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKR 149
G G GGD GG GG GGG R G G G G R G R
Sbjct: 457 GDRGGGYGGDRGGGYGGDRGGGYGGDRGGY---GGDRGGGYGGDRGGYGGDR 505
Score = 42.7 bits (99), Expect = 6e-04
Identities = 55/150 (36%), Positives = 58/150 (38%), Gaps = 35/150 (23%)
Query: 6 GGGRCCPEQEEGESAAGG-SGAGGDSAIEQGGQGSALAPSPVSG----VRREGARGGGRG 60
GGGR G GG G GGD G + P+P G RR
Sbjct: 331 GGGR---RGRGGYRGRGGFQGRGGDPK-----SGDWVCPNPSCGNMNFARRNSCNQCNEP 382
Query: 61 RGRWKQAGRGGGVCGRGRGRGRGRGRG-RGRGRGRGRPPSG------GSGLGGD---GGG 110
R + R G G RGRG G RG RGRG GRG G G G GGD GGG
Sbjct: 383 R---PEDSRPSG--GDFRGRGYGGERGYRGRG-GRGGDRGGYGGDRSGGGYGGDRSSGGG 436
Query: 111 CGGGGSGGGGAPRREPVPFPSGSAGPGPRG 140
G SGGG R SG G RG
Sbjct: 437 YSGDRSGGGYGGDR------SGGGYGGDRG 460
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/126 (30%), Positives = 41/126 (32%), Gaps = 51/126 (40%)
Query: 69 RGGGVCGRGRGRGRGRGRG----------------------------------------- 87
RGGG G RGRG RGRG
Sbjct: 326 RGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPE 385
Query: 88 ---------RGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGG-GAPRREPVPFPSGSAGPG 137
RGRG G R G G GGD GG GG SGGG G R + +G G
Sbjct: 386 DSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGG 445
Query: 138 PRGPRA 143
G R+
Sbjct: 446 YGGDRS 451
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/54 (42%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 72 GVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRRE 125
G RG G +G GRGRG GR P GS GGD GG G PR +
Sbjct: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSS-GGDRGGFKNFGGHRDYGPRTD 223
Score = 34.7 bits (78), Expect = 0.16
Identities = 32/93 (34%), Positives = 37/93 (39%), Gaps = 4/93 (4%)
Query: 6 GGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWK 65
GG R + G G GGD + +GG G G R G GG R G +
Sbjct: 502 GGDRGGYGGDRGGYGGDRGGYGGDRS--RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY- 558
Query: 66 QAGRGGGVCG-RGRGRGRGRGRGRGRGRGRGRP 97
RGGG G RG G+ GR R R RP
Sbjct: 559 GGDRGGGYGGDRGGYGGKMGGRNDYRNDQRNRP 591
Score = 32.3 bits (72), Expect = 0.80
Identities = 17/41 (41%), Positives = 22/41 (53%)
Query: 53 GARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRG 93
G++GGGRGRG + + GRG G RG + G R G
Sbjct: 179 GSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYG 219
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 57.4 bits (137), Expect = 2e-08
Identities = 48/141 (34%), Positives = 51/141 (36%), Gaps = 17/141 (12%)
Query: 7 GGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQ 66
GGR G GG GG G G + S SG R GGG G G
Sbjct: 727 GGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNS--SGHRPHEGPGGGMGSGHRPH 784
Query: 67 AGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREP 126
G GG + G G G G G G G G P G G GG G+GGG P P
Sbjct: 785 EGPGGSM-GGGGGHRPHEGPGGGISGGSGHRPHEGPG--------GGMGAGGGHRPHEGP 835
Query: 127 VPFPSGSA------GPGPRGP 141
GS GPG GP
Sbjct: 836 GGSMGGSGGHRPHEGPGHGGP 856
Score = 56.2 bits (134), Expect = 5e-08
Identities = 48/129 (37%), Positives = 51/129 (39%), Gaps = 9/129 (6%)
Query: 17 GESAAGGSGAG-GDSAIEQGGQGSALAPSPVSGVR--REGARGGGRGRGRWKQAGRGGGV 73
G GG G G G +GG+G P P R R G GGG GR G GGG+
Sbjct: 689 GGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGR---GGPGGGM 745
Query: 74 CGRGRGR---GRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFP 130
G G R G G G G G P GG G G GG GGGG R P
Sbjct: 746 VGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGG 805
Query: 131 SGSAGPGPR 139
S G G R
Sbjct: 806 GISGGSGHR 814
Score = 44.3 bits (103), Expect = 2e-04
Identities = 49/146 (33%), Positives = 52/146 (35%), Gaps = 22/146 (15%)
Query: 2 RAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVR-REGARGG-GR 59
R H G G GGS GG G G ++ SG R EG GG G
Sbjct: 768 RPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGG--SGHRPHEGPGGGMGA 825
Query: 60 GRGRWKQAGRGGGVCGRGRGR---GRGRGRGRG---------RGRG-RGRPPSGGSGLGG 106
G G G GG + G G R G G G G RG RG PP G G
Sbjct: 826 GGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDG 885
Query: 107 DGGGCGG-----GGSGGGGAPRREPV 127
G G GG GG GG PV
Sbjct: 886 PGHGGGGHRGHDGGHSHGGDMSNRPV 911
Score = 38.5 bits (88), Expect = 0.011
Identities = 39/125 (31%), Positives = 45/125 (36%), Gaps = 19/125 (15%)
Query: 41 LAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGR-----------GRG 89
L P P++ G GG +G + G GG + G G G G G
Sbjct: 620 LGPGPIANGFPPGGPGGPKGMQHFPP-GPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDP 678
Query: 90 RGRGRGRPPSGGSGLGGDGGGCG----GGGSGGGGAPRREPVPF---PSGSAGPGPRGPR 142
G G P GG GG G G G G G GG P P PF G +G GP R
Sbjct: 679 FWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGR 738
Query: 143 ATESG 147
G
Sbjct: 739 GGPGG 743
Score = 30.0 bits (66), Expect = 4.0
Identities = 22/57 (38%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 103 GLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAG--PGPRGPRATESGKRMDCPALPP 157
GL G G G GG G P+ FP G G PGP G G R+ P PP
Sbjct: 618 GLLGPGPIANGFPPGGPGGPKGMQ-HFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPP 673
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,390,373
Number of Sequences: 37866
Number of extensions: 1424006
Number of successful extensions: 31886
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 765
Number of HSP's successfully gapped in prelim test: 784
Number of HSP's that attempted gapping in prelim test: 10181
Number of HSP's gapped (non-prelim): 9140
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.