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Search of human proteins with 4504733
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504733 insulin receptor substrate 4 [Homo sapiens]
(1257 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 2557 0.0
gi|5031805 insulin receptor substrate 1 [Homo sapiens] 317 5e-86
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 298 3e-80
gi|55956899 keratin 9 [Homo sapiens] 108 4e-23
gi|47132620 keratin 2 [Homo sapiens] 94 6e-19
gi|62122917 filaggrin family member 2 [Homo sapiens] 94 1e-18
gi|109255251 loricrin [Homo sapiens] 91 7e-18
gi|119395750 keratin 1 [Homo sapiens] 90 1e-17
gi|57864582 hornerin [Homo sapiens] 89 3e-17
gi|195972866 keratin 10 [Homo sapiens] 88 4e-17
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 86 3e-16
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 85 4e-16
gi|109452587 family with sequence similarity 98, member B isofor... 81 5e-15
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 81 7e-15
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 79 4e-14
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 78 5e-14
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 78 6e-14
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 78 6e-14
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 78 6e-14
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 78 6e-14
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 78 6e-14
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 77 8e-14
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 75 5e-13
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 75 5e-13
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 74 9e-13
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 74 1e-12
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 72 3e-12
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 72 3e-12
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 72 3e-12
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 72 4e-12
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 2557 bits (6628), Expect = 0.0
Identities = 1257/1257 (100%), Positives = 1257/1257 (100%)
Query: 1 MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTAT 60
MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTAT
Sbjct: 1 MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTAT 60
Query: 61 GSRSDSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH 120
GSRSDSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH
Sbjct: 61 GSRSDSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH 120
Query: 121 SVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV 180
SVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV
Sbjct: 121 SVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV 180
Query: 181 AENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVK 240
AENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVK
Sbjct: 181 AENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVK 240
Query: 241 PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST 300
PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST
Sbjct: 241 PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST 300
Query: 301 VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH 360
VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH
Sbjct: 301 VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH 360
Query: 361 LGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGR 420
LGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGR
Sbjct: 361 LGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGR 420
Query: 421 RSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQ 480
RSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQ
Sbjct: 421 RSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQ 480
Query: 481 EGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGS 540
EGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGS
Sbjct: 481 EGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGS 540
Query: 541 GGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS 600
GGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS
Sbjct: 541 GGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS 600
Query: 601 DGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVD 660
DGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVD
Sbjct: 601 DGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVD 660
Query: 661 RGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPM 720
RGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPM
Sbjct: 661 RGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPM 720
Query: 721 APQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYM 780
APQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYM
Sbjct: 721 APQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYM 780
Query: 781 FMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRG 840
FMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRG
Sbjct: 781 FMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRG 840
Query: 841 LDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYK 900
LDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYK
Sbjct: 841 LDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYK 900
Query: 901 IKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYV 960
IKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYV
Sbjct: 901 IKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYV 960
Query: 961 NVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVI 1020
NVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVI
Sbjct: 961 NVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVI 1020
Query: 1021 FNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQ 1080
FNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQ
Sbjct: 1021 FNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQ 1080
Query: 1081 ERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASAL 1140
ERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASAL
Sbjct: 1081 ERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASAL 1140
Query: 1141 AAAPGIGAAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAHNPSANLARGD 1200
AAAPGIGAAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAHNPSANLARGD
Sbjct: 1141 AAAPGIGAAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAHNPSANLARGD 1200
Query: 1201 NQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTHVRMDFARRDNQFDSPKRGR 1257
NQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTHVRMDFARRDNQFDSPKRGR
Sbjct: 1201 NQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTHVRMDFARRDNQFDSPKRGR 1257
>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
Length = 1242
Score = 317 bits (812), Expect = 5e-86
Identities = 300/976 (30%), Positives = 414/976 (42%), Gaps = 203/976 (20%)
Query: 78 EVCKRGYLRKQKHGHRRYFVLKLET-ADAPARLEYYENARKFRHSVRAAAAAAAAAASGA 136
+V K GYLRK K H+R+FVL+ + A PARLEYYEN +K+RH A
Sbjct: 12 DVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSA------------ 59
Query: 137 AIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSR 196
P+R I L CF++++RAD++ +HL+AL+T+DE+FA+ A++E+EQ+SWY L +
Sbjct: 60 -------PKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQ 112
Query: 197 LILESKRRRCGT--LGAQPDGEPAA-----------LAAAAAAEPPFYKDVWQVIVKPRG 243
L +K G LGA G + L+ P +K+VWQVI+KP+G
Sbjct: 113 LHNRAKGHHDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKG 172
Query: 244 LGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIG 303
LG K L G++RLCLT + + FV+LN+E A+VV+QL++IRRCGHSE +FF+EVGRS V G
Sbjct: 173 LGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTG 232
Query: 304 PGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRHLGL 363
PGE WMQVDD VVAQNMHE LE MRA+ +DE+R R +S S S ++ +++ R HL
Sbjct: 233 PGEFWMQVDDSVVAQNMHETILEAMRAM-SDEFRPRSKSQSSSNCSNPISVPLRRHHLNN 291
Query: 364 VPLEPGGWLRRSRFEQFC---------------HLRAIGDGEDEMLFTRRFVTPSEPV-- 406
P G RRSR E +RA DGE M +R PV
Sbjct: 292 PPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTM--SRPASVDGSPVSP 349
Query: 407 ------AHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEV 460
AH RG L R++ +PAS R +PS P + SS
Sbjct: 350 STNRTHAHRHRGSARLHPPLNHSRSIPMPAS---RCSPSATSP---------VSLSSSST 397
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
SG GS + P + S +G S GG S+ + SS +
Sbjct: 398 SGHGS-----------------TSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRS 440
Query: 521 QCSGEGQGSRG-GQGSNGQGSGGNQCSRDGQGTAGGHGSGGG---QRPGGGHGSGGGQGP 576
S G + G+ N G+G + G R G GH G G
Sbjct: 441 SFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGL 500
Query: 577 GDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLT------QSKQQQMPPP 630
G S G + +D D K +T QS +
Sbjct: 501 G---------TSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEY 551
Query: 631 PPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRAR 690
P PP GG+G G+ G F R +E E P G HR
Sbjct: 552 TEMMPAYPPGGGSG--GRLPGHRHSAFVPTRSYPEEGLEMH-------PLERRGGHHRPD 602
Query: 691 AFDEDEDDPYVPMRPGVATPLVS----SSDYMPMAPQNVSASK------KRHSRSPFEDS 740
+ DD Y+PM PGVA P+ S S DYMPM+P++VSA + +RH + D
Sbjct: 603 SSTLHTDDGYMPMSPGVA-PVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQR--VDP 659
Query: 741 RGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGA-------IPKNP 793
GYMMM P S +P P ++ + S G G PK P
Sbjct: 660 NGYMMMSP--SGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPP 717
Query: 794 RNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNS------------EYVPMLPGKFLGRGL 841
GG Y ++ SP+G ++ S ++ P+L L R
Sbjct: 718 VESSGGKLLPCTGDYMNM------SPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSF 771
Query: 842 DKEVSYNWDPKDAA-------SKPSGEGSFSKPGDGGSPSKPSD---------------- 878
K +P++ A S SG ++ D S S SD
Sbjct: 772 -KHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLP 830
Query: 879 ---------HEPPK--------NKAKRPNRLSFITKGYKIKPKPQKPTHEQR------EA 915
H P K ++ RP RLS P+ ++ +Q+ E
Sbjct: 831 HPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEP 890
Query: 916 DSSSDYVNMDFTKRES 931
S +YVN++F +S
Sbjct: 891 KSPGEYVNIEFGSDQS 906
Score = 40.0 bits (92), Expect = 0.014
Identities = 30/102 (29%), Positives = 35/102 (34%), Gaps = 8/102 (7%)
Query: 559 GGGQRPGGGHGSGGGQGPGDGHGSGGGKN--------SGGGKGSGSGKGSDGDGERGKSL 610
G G GGG GS H S +N G K G+ G E G +
Sbjct: 1120 GAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNY 1179
Query: 611 KKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGR 652
Q Q+ P P PPPPPPP G+ S R
Sbjct: 1180 IDLDLVKDFKQCPQECTPEPQPPPPPPPHQPLGSGESSSTRR 1221
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 298 bits (762), Expect = 3e-80
Identities = 350/1213 (28%), Positives = 494/1213 (40%), Gaps = 290/1213 (23%)
Query: 79 VCKRGYLRKQKHGHRRYFVLKLE------------TADAPARLEYYENARKFRHSVRAAA 126
V K GYLRKQKHGH+R+FVL+ +A P RLEYYE+ +K+R A
Sbjct: 31 VRKCGYLRKQKHGHKRFFVLRGPGAGGDEATAGGGSAPQPPRLEYYESEKKWRSKAGA-- 88
Query: 127 AAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESE 186
P+RVI L C ++++RADA++++LIAL+T+DEYFA+ AENE E
Sbjct: 89 -----------------PKRVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQE 131
Query: 187 QESWYLLLSRLILESKRRRCGTLGAQPDGEPAAL------------AAAAAAEPPF---- 230
QE WY L+ L+ E R A P PAA A AA AE +
Sbjct: 132 QEGWYRALTDLVSEG---RAAAGDAPPAAAPAASCSASLPGALGGSAGAAGAEDSYGLVA 188
Query: 231 -----YKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRC 285
Y++VWQV +KP+GLG K L+GV+RLCL+ + FV+LN E SV +QL++IRRC
Sbjct: 189 PATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRC 248
Query: 286 GHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALC-ADEYRARCRSYS 344
GHS+ +FF+EVGRS V GPGELWMQ DD VVAQN+HE LE M+AL E+R R +S S
Sbjct: 249 GHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQS 308
Query: 345 I-SIGAHLLTLLSARRHLGLVPLEPG--GWLRRSRFEQF-----------CHLRAIGDGE 390
S H +++ ARRH LV L P G +RRSR + C +R +G+
Sbjct: 309 SGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGD 368
Query: 391 DEMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAP 450
G R VSV S L+P P R
Sbjct: 369 ---------------------GGAAAGAAAAGARPVSVAGS---PLSPGPVR-------- 396
Query: 451 NNGARLSSEVSGSGSGNFGEEGN-----PQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ 505
A LS S + SG G G+ P G Q ++ + GS
Sbjct: 397 ---APLSR--SHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSS 451
Query: 506 GSNGQGSSSHSSGGNQ------CSGEGQ-GSRGGQGSNGQGSGGNQCSRDGQGTAGG--- 555
+G GS G + G GQ S G ++G S S D G++ G
Sbjct: 452 SGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLR 511
Query: 556 ----HGSGG----GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
H S + P G GGG+ G + G SG + D +RG
Sbjct: 512 AFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQ-DLDRG 570
Query: 608 KSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKEC 667
L+KR+Y T ++Q+ +P P G +G RL + K
Sbjct: 571 --LRKRTY-SLTTPARQRPVPQPSSASLDEYTLMRATFSGSAG---RLCPSCPASSPKVA 624
Query: 668 KE--AKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVA-----TPLVSSSDYMPM 720
++ D EI G HR+ + + DD Y+PM PG A + S DYMPM
Sbjct: 625 YHPYPEDYGDIEI------GSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPM 678
Query: 721 APQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPA-------PSPPKAPDTNKEDDSKDN 773
+P +VSA K+ + + P P P+ + +S
Sbjct: 679 SPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPE 738
Query: 774 DS----------------------ESDYMFMAPGAGAIPKNPRN------PQGGSSSKS- 804
DS DY+ ++P P + GG +
Sbjct: 739 DSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGV 798
Query: 805 -WSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDK---EVSYNWDPKDAASKPSG 860
Y SLP +++ D+ +YV L +GR L++ E P AAS G
Sbjct: 799 PGCCYSSLPRSYKAPYTCGGDSDQYV--LMSSPVGRILEEERLEPQATPGPSQAAS-AFG 855
Query: 861 EGSFSKPGD-GGSPSKPSDHEP-----PKNKAKRPNRLSF-------ITKGYKIKPKPQK 907
G P SP +PS P + +A RP RLS Y + P+P+
Sbjct: 856 AGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKS 915
Query: 908 PTHEQREADSSSDYVNMDF----------------------TKRESNTPAPST-QGLPDS 944
P +Y+N+DF + +++PA S G P
Sbjct: 916 P----------GEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTP-- 963
Query: 945 WGIIAEPRQ-SAFSNYVNVEF--------GVPFPNPANDLSDLLR--------AIPRANP 987
G ++ RQ S S+Y+N++F G P +P L LL +P
Sbjct: 964 -GTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPS 1022
Query: 988 LSLDSARWPLPPLP--------------LSATGSNAIE-------EEGDYIEVIFNSAMT 1026
S S+ P PP P +A G A + GDY E+ F A T
Sbjct: 1023 ASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAAT 1082
Query: 1027 PAMALA----DSAIRYDAETG---RIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEE 1079
P +A A R + T R+ +++ S ++ L S+ +P A++++ +
Sbjct: 1083 PPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSG--VEAFLQASQPPDPHRGAKVIRADP 1140
Query: 1080 QERRRPQSRSQSF 1092
Q RR S S++F
Sbjct: 1141 QGGRRRHS-SETF 1152
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 108 bits (269), Expect = 4e-23
Identities = 68/158 (43%), Positives = 76/158 (48%), Gaps = 19/158 (12%)
Query: 453 GARLSSEVSGSGS---GNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNG 509
G + E SG+G G G G G+ + GSGG Y G G+G G GGG GS G
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSY-----GGGGSGGGYGGGSGSRG 514
Query: 510 QGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG 569
S+ G SG G GS GG G GSGG G+ GGH G G GGG G
Sbjct: 515 GSGGSYGGG----SGSGGGSGGGYGG---GSGGGHSG----GSGGGHSGGSGGNYGGGSG 563
Query: 570 SGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
SGGG G G G GSG SGG G GSG G + G G
Sbjct: 564 SGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYG 601
Score = 98.6 bits (244), Expect = 3e-20
Identities = 68/151 (45%), Positives = 72/151 (47%), Gaps = 20/151 (13%)
Query: 453 GARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGS 512
G+R S S G G+ G G G GSGG Y GSG+G GSGGG G G
Sbjct: 488 GSRGGSGGSYGGGGSGGGYGGGSGSRG--GSGGSY----GGGSGSGGGSGGGYGGGSGGG 541
Query: 513 SSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGG 572
S SGG G G GG GS G GSGG G GG GS GG GG HG G
Sbjct: 542 HSGGSGGGHSGGSGGNYGGGSGSGG-GSGG--------GYGGGSGSRGGS--GGSHGGGS 590
Query: 573 GQGPGDGHGSGGGK---NSGGGKGSGSGKGS 600
G G G GGG+ SGGG G GSGK S
Sbjct: 591 GFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Score = 76.6 bits (187), Expect = 1e-13
Identities = 60/152 (39%), Positives = 69/152 (45%), Gaps = 17/152 (11%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS 516
SS +S SG G G G SGG + S +G G GGG+ S+ SS +
Sbjct: 8 SSYLSRSGGGGGGGLG----------SGGSIRSSYSRFSSSGGGGGGGRFSS---SSGYG 54
Query: 517 SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGP 576
G ++ G G G G G GG S G G GG GG GGG+ S GG G
Sbjct: 55 GGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGAS-GGGYSSSGGFGG 113
Query: 577 GDGHGSGGGKNSGGGKGSG-SGKGSDGDGERG 607
G G GSGGG GGG GSG G G G G G
Sbjct: 114 GFGGGSGGG--FGGGYGSGFGGFGGFGGGAGG 143
Score = 69.7 bits (169), Expect = 2e-11
Identities = 55/169 (32%), Positives = 69/169 (40%), Gaps = 16/169 (9%)
Query: 458 SEVSGSGSGNFGEEGNPQGKEDQ------EGSGGDYMPMNNWGSGNGRGSG-GGQGSNGQ 510
S G G G G G+ + + G GG + + +G G+ R G GG GS G
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 511 GSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
S GG S G G GG G SGG S G G G GSGGG GGG+GS
Sbjct: 72 SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGF--GGGYGS 129
Query: 571 GGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKL 619
G G G GG GG G ++ + + + SY K+
Sbjct: 130 GFG-------GFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKV 171
Score = 60.5 bits (145), Expect = 1e-08
Identities = 49/133 (36%), Positives = 58/133 (43%), Gaps = 26/133 (19%)
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGH 580
+ SG G+ GG+G GSGG+ G+G+ GG SGG GG GSGGG G G G
Sbjct: 466 ESSGAGKIGLGGRG----GSGGSY----GRGSRGG--SGGSY---GGGGSGGGYGGGSGS 512
Query: 581 GSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPA 640
G G + GGG GSG G G G G S G S
Sbjct: 513 RGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNY-------------G 559
Query: 641 GGTGGKGKSGGRF 653
GG+G G SGG +
Sbjct: 560 GGSGSGGGSGGGY 572
Score = 37.0 bits (84), Expect = 0.12
Identities = 26/75 (34%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 445 HPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR---GS 501
H + N S GSG G G G+ G G G + + G G GS
Sbjct: 550 HSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGS 609
Query: 502 GGGQGSNGQGSSSHS 516
GGG G G G SSHS
Sbjct: 610 GGGYG-GGSGKSSHS 623
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 94.4 bits (233), Expect = 6e-19
Identities = 58/121 (47%), Positives = 68/121 (56%), Gaps = 13/121 (10%)
Query: 493 WGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGT 552
+G GRGS G G GSSS+ SGG Q GSRGG G G SGG S G G+
Sbjct: 518 FGGSGGRGSSSG-GGYSSGSSSYGSGGRQ-----SGSRGGSGGGGSISGGGYGS--GGGS 569
Query: 553 AGGHGSGGGQR----PGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGK 608
G +GSGGG + GGG+GSGGG+ G GS GG +SGGG GSG G S G G+
Sbjct: 570 GGRYGSGGGSKGGSISGGGYGSGGGK-HSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGE 628
Query: 609 S 609
+
Sbjct: 629 A 629
Score = 84.0 bits (206), Expect = 8e-16
Identities = 57/125 (45%), Positives = 63/125 (50%), Gaps = 19/125 (15%)
Query: 482 GSGGDYMPMNNWGSGNGRGSGG---GQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ 538
GSGG SG G SG G G GS S GG SG G GS GG G
Sbjct: 520 GSGG-----RGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGR-Y 573
Query: 539 GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGK 598
GSGG S+ G + GG+GSGGG+ GG GS GG G G+GSGGG GS S K
Sbjct: 574 GSGGG--SKGGSISGGGYGSGGGKHSSGG-GSRGGSSSGGGYGSGGG-------GSSSVK 623
Query: 599 GSDGD 603
GS G+
Sbjct: 624 GSSGE 628
Score = 63.9 bits (154), Expect = 9e-10
Identities = 50/146 (34%), Positives = 59/146 (40%), Gaps = 8/146 (5%)
Query: 455 RLSSEVSGSGSGNFGEEGNPQGKEDQEG----SGGDYMPMNNWGSGNGRGSGGGQGSN-- 508
++S + G G G G G G G S + ++ G G G GGG GS
Sbjct: 4 QISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSL 63
Query: 509 -GQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGG 567
G G + S G G G+ GG G G G GG G G +GG GGG GG
Sbjct: 64 VGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGG-FGGGR 122
Query: 568 HGSGGGQGPGDGHGSGGGKNSGGGKG 593
G GG G G G GG GG G
Sbjct: 123 FGGFGGPGGVGGLGGPGGFGPGGYPG 148
Score = 63.5 bits (153), Expect = 1e-09
Identities = 51/135 (37%), Positives = 55/135 (40%), Gaps = 13/135 (9%)
Query: 482 GSGGDYMPMNNWGSGNGRGSGGGQGSNGQGS--SSHSSGGNQCSGEGQGSRGGQGSNGQ- 538
G GG + SG+ SGG + S S S H GG G G GSR G G
Sbjct: 11 GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTK 70
Query: 539 -------GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG--GGKNSG 589
G GG + G G GG G GGG GGG G GG G G G G GG
Sbjct: 71 SISISVAGGGGGFGAAGGFGGRGG-GFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGP 129
Query: 590 GGKGSGSGKGSDGDG 604
GG G G G G G
Sbjct: 130 GGVGGLGGPGGFGPG 144
Score = 52.0 bits (123), Expect = 4e-06
Identities = 36/95 (37%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 452 NGARLSSEVSGSGSGNF---GEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSN 508
+G R S GSG G G G+ G + GSGG SG G GSGGG+ S+
Sbjct: 541 SGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG--SKGGSISGGGYGSGGGKHSS 598
Query: 509 GQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGN 543
G GS SS G G GS +GS+G+ G +
Sbjct: 599 GGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSS 633
Score = 51.2 bits (121), Expect = 6e-06
Identities = 37/102 (36%), Positives = 40/102 (39%), Gaps = 18/102 (17%)
Query: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS------------- 570
G G G RG + SGG++ S HG GGG GGG GS
Sbjct: 14 GGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSIS 73
Query: 571 ----GGGQGPGDGHGSGG-GKNSGGGKGSGSGKGSDGDGERG 607
GGG G G G GG G GGG G G G G G G
Sbjct: 74 ISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGG 115
Score = 48.1 bits (113), Expect = 5e-05
Identities = 41/128 (32%), Positives = 46/128 (35%), Gaps = 37/128 (28%)
Query: 525 EGQGSR--GGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQR------------------- 563
EG+ R G SN S + + G GG+
Sbjct: 485 EGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGR 544
Query: 564 --------------PGGGHGSGGGQGP--GDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
GGG+GSGGG G G G GS GG SGGG GSG GK S G G RG
Sbjct: 545 QSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRG 604
Query: 608 KSLKKRSY 615
S Y
Sbjct: 605 GSSSGGGY 612
Score = 41.2 bits (95), Expect = 0.006
Identities = 42/113 (37%), Positives = 45/113 (39%), Gaps = 33/113 (29%)
Query: 456 LSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSH 515
+S V+G G G FG G G G GRG G G GS+ G S
Sbjct: 72 ISISVAGGGGG-FGAAG---------GFG-------------GRGGGFGGGSSFGGGSGF 108
Query: 516 SSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGH 568
S GG G G G GG G G G G G G GG G GG PGG H
Sbjct: 109 SGGGFGGGGFGGGRFGGFGGPG-GVG-------GLGGPGGFGPGG--YPGGIH 151
Score = 34.7 bits (78), Expect = 0.59
Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 21/79 (26%)
Query: 451 NNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQ 510
+ G +SG G G+ G + SGG GS G SGGG GS G
Sbjct: 575 SGGGSKGGSISGGGYGSGG---------GKHSSGG--------GSRGGSSSGGGYGSGGG 617
Query: 511 GSSSHSSGGNQCSGEGQGS 529
GSSS SGE GS
Sbjct: 618 GSSSVKGS----SGEAFGS 632
Score = 33.1 bits (74), Expect = 1.7
Identities = 26/86 (30%), Positives = 29/86 (33%), Gaps = 33/86 (38%)
Query: 569 GSGG-GQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQM 627
GSGG G G G+ SG GG+ SGS GS G G
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSIS-------------------- 559
Query: 628 PPPPPPPPPPPPAGGTGGKGKSGGRF 653
GG G G SGGR+
Sbjct: 560 ------------GGGYGSGGGSGGRY 573
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 93.6 bits (231), Expect = 1e-18
Identities = 71/173 (41%), Positives = 89/173 (51%), Gaps = 21/173 (12%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSS---H 515
E+S S +FG+ G+ G+ G G SG+G+ SG GQ + G SS H
Sbjct: 723 ELSSGQSSSFGQHGSGSGQSSGFGQHG---------SGSGQSSGFGQHESRSGQSSYGQH 773
Query: 516 SSGGNQCSGEGQ-GSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGG 573
SSG +Q SG GQ GSR G GSG +Q + GQ +GSG GQ G G HGSG G
Sbjct: 774 SSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQ-----YGSGSGQSAGFGQHGSGSG 828
Query: 574 QGPGDG-HGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
Q G G H S ++S G GSGS + S G G+ G S + S FG+ S Q
Sbjct: 829 QSSGFGQHESRSHQSSYGQHGSGSSQ-SSGYGQHGSSSGQTSGFGQHRSSSGQ 880
Score = 89.0 bits (219), Expect = 3e-17
Identities = 72/189 (38%), Positives = 93/189 (49%), Gaps = 22/189 (11%)
Query: 451 NNGARLSSEVSGSGSGN---FGEEGNPQGKEDQEGSGGDYMPMNNWG---SGNGRGSGGG 504
++G S GSGSG FG+ G+ G+ G +++G SG+ + SG G
Sbjct: 725 SSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYG 784
Query: 505 QGSNGQ--GSSSHSSGGNQCSGEGQ-----GSRGGQGSNGQGSG-----GNQCSRDGQGT 552
Q + Q G H SG +Q +G GQ G G G +G GSG G SR Q +
Sbjct: 785 QHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSS 844
Query: 553 AGGHGSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDGERGKS 609
G HGSG Q G G HGS GQ G G H S G+ SG G+ GSGSG+ S G G+ G
Sbjct: 845 YGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQ-SSGFGQHGTG 903
Query: 610 LKKRSYFGK 618
+ S FG+
Sbjct: 904 SGQYSGFGQ 912
Score = 87.8 bits (216), Expect = 6e-17
Identities = 77/199 (38%), Positives = 90/199 (45%), Gaps = 36/199 (18%)
Query: 453 GARLSSEVSGSGSGNFGEE-GNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQG 511
G S SG G G G G S G Y GSG+G+ SG GQ
Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQ------ 899
Query: 512 SSSHSSGGNQCSGEGQ-GSRGGQGSNGQ-GSGGNQCSRDGQ-GTAGG-------HGSGGG 561
H +G Q SG GQ SR Q S GQ GSG +Q S GQ G++ G H SG G
Sbjct: 900 ---HGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSG 956
Query: 562 QRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-------------GSGSGKGSDGDGER 606
Q G G HGSG GQ G G H SG GK+SG G+ GSGS + S G G+
Sbjct: 957 QSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQ-SSGYGQH 1015
Query: 607 GKSLKKRSYFGKLTQSKQQ 625
G S + + FG+ S Q
Sbjct: 1016 GSSSGQTTGFGQHRSSSGQ 1034
Score = 87.8 bits (216), Expect = 6e-17
Identities = 73/180 (40%), Positives = 88/180 (48%), Gaps = 24/180 (13%)
Query: 462 GSGSGN---FGEEGNPQGKEDQEGSGGDYMPMNNWG---SGNGRGSGGGQ--GSNGQ--G 511
GSGSG FG+ + GK G +N+G SG+ + SG GQ S+GQ G
Sbjct: 965 GSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTG 1024
Query: 512 SSSHSSGGNQCSGEGQGSRG-----GQGSNGQGSG-----GNQCSRDGQGTAGGHGSGGG 561
H S Q SG GQ G G G +G GSG G SR Q + G HGSG
Sbjct: 1025 FGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSS 1084
Query: 562 QRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGK 618
Q G G HGS GQ G G H G G++SG G+ GSGSG+ S G G+ G K S F +
Sbjct: 1085 QSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQ-SSGFGQHGSGTGKSSGFAQ 1143
Score = 85.5 bits (210), Expect = 3e-16
Identities = 72/170 (42%), Positives = 86/170 (50%), Gaps = 19/170 (11%)
Query: 459 EVSGSGSGNFGEEGNPQGKED---QEGSG-GDYMPMNNWGSGNGRGSGGGQGSNGQGSSS 514
E + S S + + G+ GK Q GSG G GSG+G+ SG GQ + G SS
Sbjct: 457 ESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSS 516
Query: 515 ----HSSGGNQCSGEGQG-SRGGQGSNGQ-GSGGNQCSRDGQGTA------GGHGSGGGQ 562
H S Q SG GQ SR Q S GQ GSG +Q S GQ + G HG G GQ
Sbjct: 517 GFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQ 576
Query: 563 RPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDGERGKS 609
G G +GSG GQ G G HGSG G++SG G+ S SG+ S G G S
Sbjct: 577 STGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSS 626
Score = 84.7 bits (208), Expect = 5e-16
Identities = 68/178 (38%), Positives = 85/178 (47%), Gaps = 22/178 (12%)
Query: 462 GSGSGN---FGEEGNPQGKEDQEGSGGDYMPMNNWG---SGNGRGSGGGQ---------G 506
GSGSG FG+ G+ G+ G +++G SG+ + SG GQ G
Sbjct: 584 GSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFG 643
Query: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQ--GSNGQGSG-GNQCSRDGQGTAGGHGSGGGQR 563
+G GSS + G SG GQ S GQ +GQ SG G SR G + G HG G Q
Sbjct: 644 QHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQS 703
Query: 564 PG-GGHGSGGGQGPGDGHG--SGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGK 618
G G HGS GQ G G S G +S G GSGSG+ S G G+ G + S FG+
Sbjct: 704 SGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQ-SSGFGQHGSGSGQSSGFGQ 760
Score = 84.0 bits (206), Expect = 8e-16
Identities = 69/178 (38%), Positives = 84/178 (47%), Gaps = 19/178 (10%)
Query: 462 GSGSGNFG-----EEGNPQGKEDQEGSGGDYMP-MNNWGSGNGRGSGGGQGSNGQGSSS- 514
G+GSG + E + Q Q GSG GS +G+ G GQ +G G SS
Sbjct: 901 GTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSG 960
Query: 515 ---HSSGGNQCSGEGQGSRGGQGSNGQGSG-GNQCSRDGQGTAGGHGSGGGQRPG-GGHG 569
H SG Q SG GQ G +G+ SG G SR Q G HGSG Q G G HG
Sbjct: 961 FGQHGSGSGQSSGFGQHESG----SGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHG 1016
Query: 570 SGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
S GQ G G H S G+ SG G+ GSGS + S G G+ G + S FG+ +Q
Sbjct: 1017 SSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQ-SSGFGQHGTGSGQSSGFGQYESRSRQ 1073
Score = 83.6 bits (205), Expect = 1e-15
Identities = 72/170 (42%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Query: 460 VSGSG-SGNFGEEGNPQGKED--QEGSGGDYMP-MNNWGSGNGRGSGGGQG--SNGQGSS 513
VSGSG S FG+ + G Q G G GS +G+ SG GQ S+GQ SS
Sbjct: 672 VSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSS 731
Query: 514 --SHSSGGNQCSGEGQGSRGGQGSNGQGSG-GNQCSRDGQGTAGGHGSGGGQRPG-GGHG 569
H SG Q SG GQ G +GQ SG G SR GQ + G H SG Q G G HG
Sbjct: 732 FGQHGSGSGQSSGFGQHGSG----SGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHG 787
Query: 570 SGGGQGPGDGHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGK 618
S G G HGSG +++G G+ GSGSG+ S G G+ G + S FG+
Sbjct: 788 SRQTSGFGQ-HGSGSSQSTGFGQYGSGSGQ-SAGFGQHGSGSGQSSGFGQ 835
Score = 82.4 bits (202), Expect = 2e-15
Identities = 66/156 (42%), Positives = 76/156 (48%), Gaps = 20/156 (12%)
Query: 451 NNGARLSSEVSGSGSGNFGEE-GNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNG 509
N G S SG G G G G S G Y GSG+ + SG GQ
Sbjct: 998 NYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQ---- 1053
Query: 510 QGSSSHSSGGNQCSGEGQ-GSRGGQGSNGQ-GSGGNQCSRDGQ-GTAGGHGSGGGQ-RPG 565
H +G Q SG GQ SR Q S GQ GSG +Q S GQ G+ G SG GQ RPG
Sbjct: 1054 -----HGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPG 1108
Query: 566 GGHGSGGGQGPGDGHGSGGGKNSGGGK-GSGSGKGS 600
G SG GQ +GSG G++SG G+ GSG+GK S
Sbjct: 1109 SGQSSGFGQ-----YGSGSGQSSGFGQHGSGTGKSS 1139
Score = 82.0 bits (201), Expect = 3e-15
Identities = 66/166 (39%), Positives = 84/166 (50%), Gaps = 17/166 (10%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMP--MNNWGSGNGRGSGGGQGSNGQGSSS---- 514
S SG ++G+ + + G G GSG+ + +G GQ +G G S+
Sbjct: 763 SRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQ 822
Query: 515 HSSGGNQCSGEGQG-SRGGQGSNGQ-GSGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSG 571
H SG Q SG GQ SR Q S GQ GSG +Q S GQ HGS GQ G G H S
Sbjct: 823 HGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQ-----HGSSSGQTSGFGQHRSS 877
Query: 572 GGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSY 615
GQ G G HGSG G++SG G+ G+GSG+ S G G+ + SY
Sbjct: 878 SGQYSGFGQHGSGSGQSSGFGQHGTGSGQYS-GFGQHESRSHQSSY 922
Score = 81.6 bits (200), Expect = 4e-15
Identities = 67/185 (36%), Positives = 86/185 (46%), Gaps = 20/185 (10%)
Query: 451 NNGARLSSEVSGSGSGNFGEEGNPQGKED---QEGSGGDYMPMNNWGSGNGRGSGGGQ-- 505
++G VSG SG FG+ G+ G+ Q S GSG+ + SG GQ
Sbjct: 502 SSGFGQHGSVSGQSSG-FGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYG 560
Query: 506 -------GSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSG---GNQCSRDGQGTAGG 555
G +G GS + G SG GQ S GQ +G G G SR GQ + G
Sbjct: 561 SRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQ 620
Query: 556 HGSGGGQRPG-GGHGSGGGQGPGDGHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKR 613
H SG Q G G HGS G G HGSG +++G G+ GSGSG+ S G G+ +
Sbjct: 621 HSSGSSQSSGYGQHGSRQTSGFGQ-HGSGSSQSTGFGQYGSGSGQ-SSGFGQHVSGSGQS 678
Query: 614 SYFGK 618
S FG+
Sbjct: 679 SGFGQ 683
Score = 80.9 bits (198), Expect = 7e-15
Identities = 72/201 (35%), Positives = 87/201 (43%), Gaps = 45/201 (22%)
Query: 463 SGSGNFGEEGNPQGKE---DQEGSG-GDYMPMNNWGSGNGRGSGGGQGSNGQGSSS---- 514
S S +G+ G+ G+ Q SG G GSG+G+ SG GQ +G G SS
Sbjct: 930 SQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQ 989
Query: 515 ------------HSSGGNQCSGEGQ-GSRGGQ--------GSNGQ-------GSGGNQCS 546
H SG +Q SG GQ GS GQ S+GQ GSG +Q S
Sbjct: 990 HESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSS 1049
Query: 547 RDGQ-GTAGGHGSGGGQRPG-------GGHGSGGGQGPGDG-HGSGGGKNSGGGKGSGSG 597
GQ GT G SG GQ G HGSG Q G G HGS G+ SG G+
Sbjct: 1050 GFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGS 1109
Query: 598 KGSDGDGERGKSLKKRSYFGK 618
S G G+ G + S FG+
Sbjct: 1110 GQSSGFGQYGSGSGQSSGFGQ 1130
Score = 80.5 bits (197), Expect = 9e-15
Identities = 64/173 (36%), Positives = 78/173 (45%), Gaps = 29/173 (16%)
Query: 462 GSGSGN---FGEEGNPQGKED---QEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSS- 514
GSGSG FG+ G+ G+ Q S GSG+ + SG GQ + G +S
Sbjct: 811 GSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSG 870
Query: 515 ---HSSGGNQCSGEGQ-----GSRGGQGSNGQGSG-----GNQCSRDGQGTAGGHGSGGG 561
H S Q SG GQ G G G +G GSG G SR Q + G HGSG
Sbjct: 871 FGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSS 930
Query: 562 QRPG-GGHGSGGGQG-------PGDGHGSGGGKN-SGGGKGSGSGKGSDGDGE 605
Q G G HGS GQ G G SG G++ SG G+ SG G+ G G+
Sbjct: 931 QSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGK 983
Score = 77.4 bits (189), Expect = 8e-14
Identities = 61/168 (36%), Positives = 74/168 (44%), Gaps = 19/168 (11%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
S SG ++G+ + + G G G+G G G G GS S G
Sbjct: 611 SRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQ 670
Query: 521 QCSGEGQG-------SRGGQGSNGQ-GSGGNQCSRDGQ-GTAGGHGSGGGQR-------- 563
SG GQ SR G S GQ G G +Q S GQ G++ G SG GQ
Sbjct: 671 HVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSS 730
Query: 564 PGGGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDGERGKS 609
G HGSG GQ G G HGSG G++SG G+ S SG+ S G G S
Sbjct: 731 SFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSS 778
Score = 73.9 bits (180), Expect = 9e-13
Identities = 61/168 (36%), Positives = 78/168 (46%), Gaps = 28/168 (16%)
Query: 472 GNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRG 531
G+ Q E + + + GS +G+ SG GQ +G G SS G QC G G G
Sbjct: 448 GSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSS---GFGQC-GSGSGQSS 503
Query: 532 GQGSNGQGSGGNQCSRDGQ-GTAGGHGSGGGQRPG-------GGHGSGGGQGPGDG---- 579
G G +G SG Q S GQ G+ G SG GQ G HGSG Q G G
Sbjct: 504 GFGQHGSVSG--QSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGS 561
Query: 580 --------HGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGK 618
HG G G+++G G+ GSGSG+ S G G+ G + S FG+
Sbjct: 562 RETSGFGQHGLGSGQSTGFGQYGSGSGQ-SSGFGQHGSGSGQSSGFGQ 608
Score = 73.2 bits (178), Expect = 1e-12
Identities = 63/163 (38%), Positives = 73/163 (44%), Gaps = 28/163 (17%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSG-GDYMPMNNWGSGNGRGSGGGQGSNGQGSSS----H 515
SG G + DQ GS G GSG+G+ SG GQ +G G SS H
Sbjct: 449 SGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQH 508
Query: 516 SSGGNQCSGEGQ-GSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG--------- 565
S Q SG GQ GS GQ S G G ++ SR Q + G HGSG Q G
Sbjct: 509 GSVSGQSSGFGQHGSVSGQSS---GFGQHE-SRSRQSSYGQHGSGSSQSSGYGQYGSRET 564
Query: 566 ---GGHGSGGGQGPGDG-HGSGGGKNSG-----GGKGSGSGKG 599
G HG G GQ G G +GSG G++SG G G SG G
Sbjct: 565 SGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFG 607
Score = 72.8 bits (177), Expect = 2e-12
Identities = 63/165 (38%), Positives = 77/165 (46%), Gaps = 28/165 (16%)
Query: 462 GSGSGN---FGEEGNPQGKED---QEGSGGDYMP-MNNWGSGNGRGSGGGQGSNGQGSSS 514
GS SG FG+ + G+ Q GSG D G+G+G+ SG GQ + SS
Sbjct: 1016 GSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSS 1075
Query: 515 ---HSSGGNQCSGEGQGSRGGQGSN-GQGSGGNQCSRDGQGTAGG---HGSGGGQRPG-G 566
H SG +Q SG GQ GSN GQ SG Q R G G + G +GSG GQ G G
Sbjct: 1076 YGQHGSGSSQSSGYGQ-----HGSNSGQTSGFGQ-HRPGSGQSSGFGQYGSGSGQSSGFG 1129
Query: 567 GHGSGGGQGPG-------DGHGSGGGKNSGGGKGSGSGKGSDGDG 604
HGSG G+ G G S G +G + SG G+ G G
Sbjct: 1130 QHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSG 1174
Score = 64.3 bits (155), Expect = 7e-10
Identities = 61/183 (33%), Positives = 79/183 (43%), Gaps = 28/183 (15%)
Query: 470 EEGNPQGKEDQEGSGGDYMPM-NNWGSGNGRGSGGGQ---GSNGQGSSSHSSGG-NQCSG 524
E G PQ Q +G +GSG + GQ GS G+ S+S SS ++C
Sbjct: 359 ENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQ 418
Query: 525 EGQGSRGGQGSNGQGSGGNQCSRDGQGTAGG-------------------HGSGGGQRPG 565
G GS G+G +Q S Q G HGS G+ G
Sbjct: 419 YGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSG 478
Query: 566 -GGHGSGGGQGPGDGH-GSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQS 622
G HGSG GQ G G GSG G++SG G+ GS SG+ S G G+ G + S FG+
Sbjct: 479 FGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQ-SSGFGQHGSVSGQSSGFGQHESR 537
Query: 623 KQQ 625
+Q
Sbjct: 538 SRQ 540
Score = 62.8 bits (151), Expect = 2e-09
Identities = 48/146 (32%), Positives = 62/146 (42%), Gaps = 19/146 (13%)
Query: 463 SGSGNFGEEGNPQGKEDQEGS----GGDYMPMNNWGSGNGRGSGGGQGSNGQGSSS---- 514
S S +G+ G+ G+ G G +GSG+G+ SG GQ +G G SS
Sbjct: 1084 SQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQ 1143
Query: 515 ------HSSGGNQCSGEGQGSRGGQGSNGQGS----GGNQCSRDGQGTAGGHGSGGGQRP 564
SS G +G Q S GQ +G G G + D ++G H S GQ
Sbjct: 1144 HEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQST 1203
Query: 565 G-GGHGSGGGQGPGDGHGSGGGKNSG 589
G G +GSG GQ G G G SG
Sbjct: 1204 GFGQYGSGSGQSTGLGQGESQQVESG 1229
Score = 62.4 bits (150), Expect = 3e-09
Identities = 56/172 (32%), Positives = 71/172 (41%), Gaps = 19/172 (11%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
S S ++G+ G+ G G G GS +G+ SG GQ G G S S G
Sbjct: 1069 SRSRQSSYGQHGS--GSSQSSGYG-------QHGSNSGQTSGFGQHRPGSGQS--SGFGQ 1117
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCS---RDGQGTAGGHGSGGGQRPG-GGHGSGGGQGP 576
SG GQ S GQ +G G R GQ + G HG+G Q G G H SG G
Sbjct: 1118 YGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTT 1177
Query: 577 GDG-HGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQM 627
G H SG S G+ S G G+ G + + G Q + QQ+
Sbjct: 1178 SFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLG---QGESQQV 1226
Score = 58.5 bits (140), Expect = 4e-08
Identities = 57/163 (34%), Positives = 71/163 (43%), Gaps = 22/163 (13%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMP-MNNWGSGNGRGSGGGQG--SNGQGSSSH 515
E G + N K DQ GSG G+G + SG Q +GQ H
Sbjct: 397 EYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQH 456
Query: 516 SSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGH-GSGGGQ 574
S +Q G Q S+G+ SG G HGSG GQ G G GSG GQ
Sbjct: 457 ESTSSQSLGYDQHG----SSSGKTSG-----------FGQHGSGSGQSSGFGQCGSGSGQ 501
Query: 575 GPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSY 615
G G HGS G++SG G+ GS SG+ S G G+ ++ SY
Sbjct: 502 SSGFGQHGSVSGQSSGFGQHGSVSGQ-SSGFGQHESRSRQSSY 543
Score = 58.2 bits (139), Expect = 5e-08
Identities = 60/185 (32%), Positives = 77/185 (41%), Gaps = 38/185 (20%)
Query: 462 GSGSGNFGEEGNPQGKE-DQEGSGG--DYMPMN---NWGSGNGRGSGGGQGSNGQGSSSH 515
G SG E NP + Q G G + P N W +G+ + S GQ +
Sbjct: 333 GQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQ---------Y 383
Query: 516 SSGGNQCSGEGQGSRGGQGSNGQGSGGNQ---CSRDGQGTAGG-----HGSGGGQRPG-- 565
SGG+Q GQ G G S N+ C + G G++ HG+G Q G
Sbjct: 384 GSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFE 443
Query: 566 ----------GGHGSGGGQGPG-DGHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKR 613
G H S Q G D HGS GK SG G+ GSGSG+ S G G+ G +
Sbjct: 444 QHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQ-SSGFGQCGSGSGQS 502
Query: 614 SYFGK 618
S FG+
Sbjct: 503 SGFGQ 507
Score = 58.2 bits (139), Expect = 5e-08
Identities = 59/184 (32%), Positives = 71/184 (38%), Gaps = 31/184 (16%)
Query: 462 GSGSGN---FGEEGNPQGKED---QEGSG-GDYMPMNNWGSGNGRGSGGGQ--------- 505
GS SG FG+ G+ Q GSG G GSG G+ SG Q
Sbjct: 1093 GSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSS 1152
Query: 506 -GSNGQGSSSHSSGGNQCSGEGQGSRGGQ---GSNGQGSGGNQCSRDGQGTA-GGHGSGG 560
G +G GSS S G SG G + GQ GS+ S G S GQ T G +GSG
Sbjct: 1153 YGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGS 1212
Query: 561 GQRPGGGHGSG----------GGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSL 610
GQ G G G G Q G ++S G+G + GS R S
Sbjct: 1213 GQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQ 1272
Query: 611 KKRS 614
+ S
Sbjct: 1273 SENS 1276
Score = 47.0 bits (110), Expect = 1e-04
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 39/181 (21%)
Query: 463 SGSGNFGEEGNPQGK-EDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQ 521
+GS G G+ + D EG G +++ SG+ G G GSS H G
Sbjct: 1943 TGSRTTGRRGSGHSEYSDSEGPSG----VSHTHSGHTHGQAGSHYPES-GSSVHERHGTT 1997
Query: 522 C-----------SGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAG--------GHGSGGGQ 562
SG GQ ++ G + G+ + G+ D +G +G HG G Q
Sbjct: 1998 HGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQ 2057
Query: 563 RPGGG------HGSGGGQ--------GPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGK 608
G HG+ GQ G G + G + G +GSG + SD + G
Sbjct: 2058 HGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGV 2117
Query: 609 S 609
S
Sbjct: 2118 S 2118
Score = 46.2 bits (108), Expect = 2e-04
Identities = 53/211 (25%), Positives = 82/211 (38%), Gaps = 21/211 (9%)
Query: 408 HSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGN 467
H R G H G +R A S +R + + R R + ++ + + S VS + SG+
Sbjct: 2066 HERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGR-RGSGHSESSDSEVHSGVSHTHSGH 2124
Query: 468 -FGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEG 526
+G+ + G+ GS G G G + SG Q + G
Sbjct: 2125 TYGQARSQHGES---------------GSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTG 2169
Query: 527 QGSRGGQGSNGQGSGGNQCSRDGQGTAGGHG-SGGGQRPGGGHGSGGGQGPGDGHGSGGG 585
+ G Q S+ S ++ + T GH S G R G SG G+ G HG G
Sbjct: 2170 SRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGR-QGTTHGQTGD 2228
Query: 586 --KNSGGGKGSGSGKGSDGDGERGKSLKKRS 614
+++ G G + +GS G RG + S
Sbjct: 2229 TTRHAHYGYGQSTQRGSRTTGRRGSGHSESS 2259
Score = 45.8 bits (107), Expect = 3e-04
Identities = 51/229 (22%), Positives = 77/229 (33%), Gaps = 41/229 (17%)
Query: 403 SEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSG 462
SE + H R G +H G +R A S ++ G+R + S
Sbjct: 1759 SESIVHERHGTIHGQTGDTTRHAHS-----------------GHGQSTQTGSRTTGRRS- 1800
Query: 463 SGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQC 522
SG + + G + S G G + G + +SG +Q
Sbjct: 1801 SGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQ- 1859
Query: 523 SGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGG---------- 572
SG GQ ++ G + G+ G+ S D + +GG + G G
Sbjct: 1860 SGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRH 1919
Query: 573 -------GQGPGDGHGSGG-----GKNSGGGKGSGSGKGSDGDGERGKS 609
G GH S G G + G +GSG + SD +G G S
Sbjct: 1920 QTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVS 1968
Score = 43.9 bits (102), Expect = 0.001
Identities = 36/139 (25%), Positives = 49/139 (35%), Gaps = 12/139 (8%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMN---NWGSGNGRGSGGGQGSNGQGSSSHSSG 518
GS S G +GN +QEGS Y + +W G R + + SH S
Sbjct: 156 GSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISP 215
Query: 519 GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQ-----RPGGGHGSGGG 573
+ E + G +G GG C + GH S Q + G SG G
Sbjct: 216 SRESGEEYESGSGSNSWERKGHGGLSCGLE----TSGHESNSTQSRIREQKLGSSCSGSG 271
Query: 574 QGPGDGHGSGGGKNSGGGK 592
H G +SG G+
Sbjct: 272 DSGRRSHACGYSNSSGCGR 290
Score = 42.7 bits (99), Expect = 0.002
Identities = 39/154 (25%), Positives = 57/154 (37%), Gaps = 5/154 (3%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWG-SGNGRGSGGGQGSNGQGSSSH 515
S E + S +G+ E E E + G G SG+G+ + G + G+ S H
Sbjct: 1365 SQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRGSGH 1424
Query: 516 SSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQG 575
S + G R G G+Q G G HG+ GQ + G
Sbjct: 1425 SESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHG 1484
Query: 576 PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKS 609
GS ++ G +GSG + SD + G S
Sbjct: 1485 KSTQRGS----STTGRRGSGHSESSDSEVHSGGS 1514
Score = 39.7 bits (91), Expect = 0.018
Identities = 51/225 (22%), Positives = 74/225 (32%), Gaps = 25/225 (11%)
Query: 447 AEAPNNGARLSSEVSGSGSGNFGEEGNPQGK-EDQEGSGGDYMPMNNWGSGNGRGSGGGQ 505
A+ +G + + GS G + + D EG G +++ SG+ G G Q
Sbjct: 2002 ADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSG----VSHTHSGHAHGQAGSQ 2057
Query: 506 ----------------GSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDG 549
G G + SG Q + G + G +GS S ++
Sbjct: 2058 HGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGV 2117
Query: 550 QGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKS 609
T GH G + G GS G HG G G G G S G R
Sbjct: 2118 SHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQ---STQTGSRTTG 2174
Query: 610 LKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFR 654
++RS + + S+ P AG G+ S G R
Sbjct: 2175 -RQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGR 2218
Score = 39.7 bits (91), Expect = 0.018
Identities = 63/268 (23%), Positives = 98/268 (36%), Gaps = 30/268 (11%)
Query: 408 HSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGN 467
H R+G +H G +R S + + + R R + + ++ + + SE S + SG+
Sbjct: 2141 HGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRS-SHSESSDSEVHSEASPTHSGH 2199
Query: 468 FGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQ 527
+ + Q GS SG+GR G G G + G Q + G
Sbjct: 2200 THSQAG--SRHGQSGS-----------SGHGR-QGTTHGQTGDTTRHAHYGYGQSTQRGS 2245
Query: 528 GSRGGQGSNGQGSGGNQCSRDGQGTAGGH--GSGGGQRPGGG---HG----SGGGQGPGD 578
+ G +GS S ++ G T GH G G Q+ G HG + G G
Sbjct: 2246 RTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTT 2305
Query: 579 GHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPP 638
HG +SG G+ + +G S +R G +Q + P
Sbjct: 2306 RHG-----HSGYGQSTQTGSRSSRASHFQSHSSERQRHGS-SQVWKHGSYGPAEYDYGHT 2359
Query: 639 PAGGTGGKGKSGGRFRLYFCVDRGATKE 666
G +GG KS L + D A K+
Sbjct: 2360 GYGPSGGSRKSISNSHLSWSTDSTANKQ 2387
Score = 39.3 bits (90), Expect = 0.024
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 14/126 (11%)
Query: 476 GKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSG------GNQCSGEGQGS 529
G+E + GSG N+W G G ++G S+S S G+ CSG G
Sbjct: 220 GEEYESGSGS-----NSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSG 274
Query: 530 RGGQGSNGQGSGGNQCSRDGQGTAGGH--GSGGGQRPGGGHGSGGGQGPGDGHGS-GGGK 586
R S G ++ + H G G Q G G G GHG GG+
Sbjct: 275 RRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQ 334
Query: 587 NSGGGK 592
SG G+
Sbjct: 335 PSGCGQ 340
Score = 38.9 bits (89), Expect = 0.031
Identities = 54/226 (23%), Positives = 76/226 (33%), Gaps = 35/226 (15%)
Query: 403 SEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSG 462
SE + H R H G +R + S + + + R R ++ SEV
Sbjct: 1532 SESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQR-----TSHSESTDSEVHS 1586
Query: 463 SGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQC 522
GS P +E G G + G+ GQ + G S SG Q
Sbjct: 1587 GGSHR------PHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSH--SGHGQS 1638
Query: 523 SGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGP---GDG 579
+ G + G Q S+ S ++ T GH G + G HG P G
Sbjct: 1639 TQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHG---QAGSQHGQSESIVPERHGTT 1695
Query: 580 HGSGG----------------GKNSGGGKGSGSGKGSDGDGERGKS 609
HG G G + G +GSG + SD +G G S
Sbjct: 1696 HGQTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVS 1741
Score = 38.5 bits (88), Expect = 0.041
Identities = 45/227 (19%), Positives = 78/227 (34%), Gaps = 23/227 (10%)
Query: 406 VAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGS 465
V+H +H G ++ S RR + R + S +GS +
Sbjct: 1284 VSHRHSEHIHTQAGSHYPKS----GSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRT 1339
Query: 466 GNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNG--------QGSSSHSS 517
+ + + SG + P + + + GS G+ + G + ++
Sbjct: 1340 SGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEAT 1399
Query: 518 GGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGG----------HGSGGGQRPGGG 567
G SG GQ ++ G + G+ G+ S D + +GG HG G Q G
Sbjct: 1400 GHGH-SGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESG 1458
Query: 568 HGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRS 614
G G G +++ G + +GS G RG + S
Sbjct: 1459 STVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESS 1505
Score = 32.7 bits (73), Expect = 2.2
Identities = 43/175 (24%), Positives = 59/175 (33%), Gaps = 39/175 (22%)
Query: 466 GNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGE 525
G+ +E + +ED+E + G R S +G SS HS G +C
Sbjct: 105 GHRHQEEESETEEDEEDTPGH--------KSGYRHSSWSEGEEHGYSSGHSRGTVKCRHG 156
Query: 526 GQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGG- 584
R G+ N SG + S+ R GH GG+ D HGS
Sbjct: 157 SNSRRLGRQGNLSSSGNQEGSQKRY-----------HRSSCGHSWSGGK---DRHGSSSV 202
Query: 585 -------------GKNSGGGKGSGSGKGS---DGDGERGKSLKKRSYFGKLTQSK 623
+ SG SGSG S G G L+ + TQS+
Sbjct: 203 ELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSR 257
Score = 31.6 bits (70), Expect = 5.0
Identities = 51/221 (23%), Positives = 68/221 (30%), Gaps = 55/221 (24%)
Query: 446 PAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNG----RGS 501
P + S+ SGS G G G+ Y + G+ RGS
Sbjct: 1440 PQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGS 1499
Query: 502 GGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQG---------------------S 540
G + S+ S HS G + SG G G Q + S
Sbjct: 1500 GHSESSD---SEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYS 1556
Query: 541 GGNQCSRDGQGTAG----GHG--------SGGGQRPGG---GHGSGGGQGP--------- 576
G Q ++ G T G H SGG RP +G G Q
Sbjct: 1557 GHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHER 1616
Query: 577 -GDGHGSGGGK--NSGGGKGSGSGKGSDGDGERGKSLKKRS 614
G HG G +S G G + +GS G + S + S
Sbjct: 1617 HGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESS 1657
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 90.9 bits (224), Expect = 7e-18
Identities = 76/225 (33%), Positives = 83/225 (36%), Gaps = 37/225 (16%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSG 518
+ SG G G G G G GSGG + GSG G GGG G G S G
Sbjct: 18 KTSGGGGGGGGSGGGGCGFFGGGGSGG-----GSSGSGCGYSGGGGYSGGGCGGGSSGGG 72
Query: 519 GNQ----CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG---SG 571
G C G GS G G GG+ C G G +G SGGG GGG G SG
Sbjct: 73 GGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSG 132
Query: 572 GGQGPGDGHG-----------------SGGGKNSGGGKGSGSGKGSDGDG--------ER 606
GG G G G S GG +SGG G GSG S G G
Sbjct: 133 GGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGG 192
Query: 607 GKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
G S G + Q P P GG+ G G SGG
Sbjct: 193 GSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG 237
Score = 85.1 bits (209), Expect = 4e-16
Identities = 83/214 (38%), Positives = 90/214 (42%), Gaps = 38/214 (17%)
Query: 461 SGSG---SGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNG-RGSGGGQGSNGQGSSSHS 516
SGSG SG G G G G GG + GSG + SGGG GS+G GS S
Sbjct: 47 SGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGG-GSSGGGSGCFS 105
Query: 517 SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHG-----SGGGQRPG------ 565
SGG G G S GG GS+G GSG C G G + G G SGGG G
Sbjct: 106 SGG---GGSGCFSSGGGGSSGGGSG---CFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQ 159
Query: 566 --GGHGSGGGQGPGDG---HGSGGGKNSG-GGKGSGSGKGSDGDGERGKSLKKRSYFGKL 619
GG SGG G G G G GGG G G GSG G GS G G +
Sbjct: 160 SYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSG--------YVSS 211
Query: 620 TQSKQQQMPPPPPPPPPPPPAGGTGGKG--KSGG 651
Q Q P P GG+GG G SGG
Sbjct: 212 QQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGG 245
Score = 84.3 bits (207), Expect = 6e-16
Identities = 63/175 (36%), Positives = 72/175 (41%), Gaps = 27/175 (15%)
Query: 489 PMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRD 548
P++ + G G GGG G G G G SG G G GG G +G G GG
Sbjct: 13 PVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGG 72
Query: 549 GQGTAGGHGSGGG---QRPGGGHGSGGGQG----PGDGHG---SGGGKNSGGGKG--SGS 596
G G GG G G G + GGG SGGG G G G G SGGG +SGGG G S
Sbjct: 73 GGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSG 132
Query: 597 GKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
G GS G G S + G+ Q + GG G SGG
Sbjct: 133 GGGSSGGGSGCFSSGGGGFSGQAVQCQSY---------------GGVSSGGSSGG 172
Score = 82.0 bits (201), Expect = 3e-15
Identities = 60/150 (40%), Positives = 69/150 (46%), Gaps = 19/150 (12%)
Query: 486 DYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQC 545
D + + G G G GGG G G G S S G+ C G G G G G SGG
Sbjct: 15 DCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGG 74
Query: 546 SRDGQGTAGGHG-----SGGGQRPGGGHG----SGGGQG---PGDGHGSGGGK---NSGG 590
G G GG G SGGG GGG G GGG G G G SGGG +SGG
Sbjct: 75 GGIG-GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGG 133
Query: 591 GKGSGSGKG---SDGDGERGKSLKKRSYFG 617
G SG G G S G G G++++ +SY G
Sbjct: 134 GGSSGGGSGCFSSGGGGFSGQAVQCQSYGG 163
Score = 79.3 bits (194), Expect = 2e-14
Identities = 75/222 (33%), Positives = 84/222 (37%), Gaps = 59/222 (26%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
SG GSG F G G G G G G+G S GG GS+G GS SSGG
Sbjct: 97 SGGGSGCFSSGGGGSGCFSSGGGGSS-------GGGSGCFSSGGGGSSGGGSGCFSSGGG 149
Query: 521 -------QCSGEGQGSRGGQGSNGQG------SGGNQCSRDGQGTAGGHGSGGGQRPG-- 565
QC G S GG G G GG+ C G G+ G GS GG G
Sbjct: 150 GFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYV 209
Query: 566 ---------------------GGHGSGG----GQGPGDGHGSGGGKNSG-------GGKG 593
GG GSGG G G G GG +SG G G
Sbjct: 210 SSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGG 269
Query: 594 SGSGKGSDGDGERGKSLKKRSYFGK----LTQSKQQQMPPPP 631
S G GS G G G S+ S GK Q++Q+Q P P
Sbjct: 270 SVCGGGSSGGGGGGSSV-GGSGSGKGVPICHQTQQKQAPTWP 310
Score = 77.4 bits (189), Expect = 8e-14
Identities = 64/150 (42%), Positives = 67/150 (44%), Gaps = 20/150 (13%)
Query: 453 GARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGS 512
G S SG GSG F G GG + GSG G GS GG GS G S
Sbjct: 162 GGVSSGGSSGGGSGCF----------SSGGGGGSVCGYSGGGSGCGGGSSGGSGS-GYVS 210
Query: 513 SSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG--- 569
S + Q S Q S GG S G GSGG+ C G G GG GG G G G
Sbjct: 211 SQQVT---QTSCAPQPSYGGGSSGGGGSGGSGCFSSGGG--GGSSGCGGGSSGIGSGCII 265
Query: 570 SGGGQGPGDGHGSGGGKNSGGGKGSGSGKG 599
SGGG G G GGG S G GSGSGKG
Sbjct: 266 SGGGSVCGGGSSGGGGGGSSVG-GSGSGKG 294
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 90.1 bits (222), Expect = 1e-17
Identities = 64/174 (36%), Positives = 74/174 (42%), Gaps = 35/174 (20%)
Query: 449 APNNGARLSSE---VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ 505
APN +S+ +SG GS G G G GG Y G+G G GGG+
Sbjct: 498 APNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSY--------GSGGGGGGGR 549
Query: 506 GSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG 565
GS G G SS+ SGG GS G G GG G G+ G S GG R G
Sbjct: 550 GSYGSGGSSYGSGG--------------GSYGSGGGGG-----GHGSYGSGSSSGGYRGG 590
Query: 566 GGHGSGGGQGPGDGHGSGGGKNSG--GGKGSGSGKGSDGDGERGKSLKKRSYFG 617
G G GG G G GSGGG + G GG+GS SG G +Y G
Sbjct: 591 SGGGGGGSSG---GRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSG 641
Score = 68.2 bits (165), Expect = 5e-11
Identities = 52/134 (38%), Positives = 59/134 (44%), Gaps = 4/134 (2%)
Query: 472 GNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRG 531
G G GS G S + R SGGG G+ SS GG+ +G G GSR
Sbjct: 10 GYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGG---GGRFSSCGGGGGSFGAGGGFGSRS 66
Query: 532 GQGSNGQGSGGNQCSRDG-QGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGG 590
G S +R G +G+ G G GGG GGG G GG G G G G GG SGG
Sbjct: 67 LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126
Query: 591 GKGSGSGKGSDGDG 604
G G G G G G
Sbjct: 127 GGFGGGGFGGGGYG 140
Score = 64.3 bits (155), Expect = 7e-10
Identities = 49/143 (34%), Positives = 56/143 (39%), Gaps = 4/143 (2%)
Query: 452 NGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGS---- 507
+G R S +G + + GG + G G G+GGG GS
Sbjct: 9 SGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLV 68
Query: 508 NGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGG 567
N GS S S + G G G GG G G G GG G G GG G GG GGG
Sbjct: 69 NLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGG 128
Query: 568 HGSGGGQGPGDGHGSGGGKNSGG 590
G GG G G G G G GG
Sbjct: 129 FGGGGFGGGGYGGGYGPVCPPGG 151
Score = 60.8 bits (146), Expect = 8e-09
Identities = 53/135 (39%), Positives = 59/135 (43%), Gaps = 24/135 (17%)
Query: 493 WGSGNGRGSGGGQGSNGQG----------SSSHSSGG-----NQCSGEGQGSRGGQGSNG 537
+ S +G SGGG S G SS+ SGG + C G G GS G G G
Sbjct: 5 FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGG-GSFGAGGGFG 63
Query: 538 QGS----GGNQCSRDGQGTAGGHGSG-GGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGK 592
S GG++ GG GSG GG GGG G GG G G G GGG GG
Sbjct: 64 SRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG---GGGIGGGGFG 120
Query: 593 GSGSGKGSDGDGERG 607
G GSG G G G G
Sbjct: 121 GFGSGGGGFGGGGFG 135
Score = 57.0 bits (136), Expect = 1e-07
Identities = 40/112 (35%), Positives = 46/112 (41%)
Query: 491 NNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQ 550
+ + SG G SG N Q ++ SS G G+ S G G G+GG SR
Sbjct: 9 SGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLV 68
Query: 551 GTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG 602
G GGG GSG G G G G GGG GG G G G G G
Sbjct: 69 NLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 89.0 bits (219), Expect = 3e-17
Identities = 82/255 (32%), Positives = 109/255 (42%), Gaps = 40/255 (15%)
Query: 439 SPARPRHPAEAPNN--------GARLSSEV----SGSGSGN-FG--EEGNPQGKEDQEGS 483
SP+R RH + + ++ G SS SGSG + FG E G+ QG +
Sbjct: 775 SPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSA 834
Query: 484 GGDYMPMNNWGSGNGRGSGGGQ--GSNGQGSS-------SHSSGGNQCSGEGQGSRGGQG 534
G + GS +G+ S GQ S+GQ SS SH + G G G G G G
Sbjct: 835 SGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHG 894
Query: 535 SNGQGSG-----GNQCSRDGQGTAGG-HGSGGGQRPGGGHGSGGGQGPG-DGHGSGGGKN 587
G GSG G S G+ ++ G HGSG GQ G GH S GQ G HGSG G +
Sbjct: 895 QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHS 954
Query: 588 SGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQM-------PPPPPPPPPPPP 639
S + GS SG+ S + + G S S +G+ +Q + P P
Sbjct: 955 SSYEQHGSRSGQSSRSE-QHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1013
Query: 640 AGGTGGKGKSGGRFR 654
G G+ S G +R
Sbjct: 1014 HGSGSGQSSSYGPYR 1028
Score = 88.2 bits (217), Expect = 4e-17
Identities = 70/184 (38%), Positives = 83/184 (45%), Gaps = 32/184 (17%)
Query: 444 RHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGK---EDQEGSGGDYMP-MNNWGSGNGR 499
+H A + + + S S +G +G+ G+ Q GSG P GSG+GR
Sbjct: 2031 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2090
Query: 500 GSGGGQGSNGQGSSS-----------------HSSGGNQCSGEGQ-GSRGGQGSNGQ--G 539
S GQ G G SS H SG SG GQ GSR GQ S G+ G
Sbjct: 2091 SSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2150
Query: 540 SGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGS 596
S SR GQ HGSG Q G G GSG G P G HGSG G +S G+ GSGS
Sbjct: 2151 SSSGSSSRYGQ-----HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS 2205
Query: 597 GKGS 600
G+ S
Sbjct: 2206 GRSS 2209
Score = 85.9 bits (211), Expect = 2e-16
Identities = 69/184 (37%), Positives = 83/184 (45%), Gaps = 32/184 (17%)
Query: 444 RHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGK---EDQEGSGGDYMP-MNNWGSGNGR 499
+H A + + + S S +G +G+ G+ Q GSG P GSG+GR
Sbjct: 1091 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 1150
Query: 500 GSGGGQGSNGQGSSS-----------------HSSGGNQCSGEGQ-GSRGGQGSNGQ--G 539
S GQ +G G SS H SG SG GQ GSR GQ S G+ G
Sbjct: 1151 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 1210
Query: 540 SGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGS 596
S S GQ HGSG Q G G GSG G P G HGSG G +S G+ GSGS
Sbjct: 1211 SSSGSSSHYGQ-----HGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS 1265
Query: 597 GKGS 600
G+ S
Sbjct: 1266 GRSS 1269
Score = 85.1 bits (209), Expect = 4e-16
Identities = 71/197 (36%), Positives = 89/197 (45%), Gaps = 23/197 (11%)
Query: 444 RHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKED---QEGSGGDYMPM-NNWGSGNGR 499
+H A + + + S S +G +G+ G+ Q GSG P GSG+GR
Sbjct: 2501 QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2560
Query: 500 GSGGGQGSNGQGSSS----HSSGGNQCS-----GEGQGSRGGQGSNGQGSG-GNQCSRDG 549
S GQ +G G SS H S Q S G G G G G +G SG ++ R G
Sbjct: 2561 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHG 2620
Query: 550 QGTA-----GGHGSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSD 601
+ G HGSG Q G G GSG GQ P G HGSG G +S G+ GSGSG+ S
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGR-SS 2679
Query: 602 GDGERGKSLKKRSYFGK 618
G L S FG+
Sbjct: 2680 SRGPYESRLGHSSVFGQ 2696
Score = 84.3 bits (207), Expect = 6e-16
Identities = 118/482 (24%), Positives = 168/482 (34%), Gaps = 91/482 (18%)
Query: 437 APSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEG-------NPQGKEDQEGSGGDYMP 489
+PSP+R RH + +G S GSGSG G + G +E G
Sbjct: 1476 SPSPSRGRHGS---GSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSG 1532
Query: 490 MNNWGSGNGRGSGGGQGSNGQGSSS----HSSGGNQCSGEGQGSRGGQGSNG---QGSGG 542
GS +G S GQ + G SS H + Q S GQ G S+G QGSG
Sbjct: 1533 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 1592
Query: 543 NQCSRDGQGTAGG--------HGSGGGQRPGGG-HGSGGGQGPGDGH------------- 580
Q GQ +G HGSG G+ G HGSG G+ G GH
Sbjct: 1593 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 1652
Query: 581 -GSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPP 638
GSG G +SG G+ GS SG+ S G+ G S + S +G+ +Q
Sbjct: 1653 HGSGSGHSSGYGQHGSRSGQSSRGE-RHGSSSRSSSRYGQHGSGSRQ------------- 1698
Query: 639 PAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDD 698
+ G G +G G+ ++ + + ++ G H + +
Sbjct: 1699 -SSGHGRQGSGSGQ---------------SPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 1742
Query: 699 PYVPMRPGVATPL---VSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPA 755
PY R G ++ S S + Q+ S S S+ + G F +
Sbjct: 1743 PY-ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG 1801
Query: 756 PSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPF 815
S ++ + S Y G+G P R+ G S S+ + S
Sbjct: 1802 QS------SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGS--GSG 1853
Query: 816 RSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSK 875
SS G++ + G G S +W SG G S GS S
Sbjct: 1854 WSSSSGRHGS--------GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG 1905
Query: 876 PS 877
S
Sbjct: 1906 QS 1907
Score = 83.6 bits (205), Expect = 1e-15
Identities = 74/227 (32%), Positives = 95/227 (41%), Gaps = 42/227 (18%)
Query: 437 APSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEG-------NPQGKEDQEGSGGDYMP 489
+PSP+R RH + +G S GSGSG G + G +E G
Sbjct: 2416 SPSPSRGRHGS---GSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2472
Query: 490 MNNWGSGNGRGSGGGQGSNGQGSSS----HSSGGNQCSGEGQGSRGGQGSNG---QGSGG 542
GS +G S GQ + G SS H + Q S GQ G S+G QGSG
Sbjct: 2473 YGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2532
Query: 543 NQCSRDGQGTAGG--------HGSGGGQRPGGG-HGSGGGQGPGDGH------------- 580
Q GQ +G HGSG G+ G HGSG G+ G GH
Sbjct: 2533 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQ 2592
Query: 581 -GSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
GSG G +SG G+ GS SG+ S G+ G S S++G+ +Q
Sbjct: 2593 HGSGSGHSSGYGQHGSRSGQSSRGE-RHGSSSGSSSHYGQHGSGSRQ 2638
Score = 83.2 bits (204), Expect = 1e-15
Identities = 70/191 (36%), Positives = 86/191 (45%), Gaps = 34/191 (17%)
Query: 448 EAPNNGARLSSEVSGSGSG---NFGEEGNPQGKEDQEG----------SGGDYMPMNNWG 494
E + G S GSGS ++G++G+ G+ G S G + + W
Sbjct: 1796 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 1855
Query: 495 SGNGR-GSGGGQGS----------NGQGSSSHSSG-GNQCSGEGQGSRGGQGSNGQGSGG 542
S +GR GSG GQ S G + H SG G+ S E GSR GQ S G+ G
Sbjct: 1856 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGS 1915
Query: 543 NQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGGQGPGDG---HGSGGGKNSG-GGKGSGSG 597
S + G HGSG Q G G HGSG GQ P HGSG G++S G GSGSG
Sbjct: 1916 ---SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSG 1972
Query: 598 -KGSDGDGERG 607
S G E G
Sbjct: 1973 WSSSRGPYESG 1983
Score = 82.8 bits (203), Expect = 2e-15
Identities = 71/201 (35%), Positives = 89/201 (44%), Gaps = 25/201 (12%)
Query: 443 PRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSG 502
P + +G S++ GSGSG G + S G + GSG+G SG
Sbjct: 203 PNYGQHGSGSGQSSSNDTHGSGSGQ------SSGFSQHKSSSGQSSGYSQHGSGSGHSSG 256
Query: 503 GGQGSNGQGSSSH------SSGGNQCSGE-GQGSRGGQGSNGQGSGGNQCS---RDGQGT 552
GQ + G SS SSG + G+ G GSR G QGSG Q R G G+
Sbjct: 257 YGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGS 316
Query: 553 A-----GGHGSGGGQRPGGGH-GSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDG 604
G HGSG GH SG GQ G G H SG G++SG K GSGSG S G
Sbjct: 317 GHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGH-SSSQG 375
Query: 605 ERGKSLKKRSYFGKLTQSKQQ 625
+ G + + S G+ S +Q
Sbjct: 376 QHGSTSGQASSSGQHGSSSRQ 396
Score = 82.8 bits (203), Expect = 2e-15
Identities = 74/230 (32%), Positives = 97/230 (42%), Gaps = 22/230 (9%)
Query: 407 AHSRRGRLHLPRGRRSRRAVS------VPASFFRRLAPSPARPRHPAEAPNNGARLSSEV 460
+HS R H R +S R+ + +S+ + + S H + +G S
Sbjct: 721 SHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVR 780
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
GS SG+ G S G Y GSG G G + +GQG S H S
Sbjct: 781 HGSSSGHSSSHGQHGSGTSCSSSCGHYES----GSGQASGFGQHESGSGQGYSQHGSASG 836
Query: 521 QCSGEGQ-GSRGGQGSNG---QGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGP 576
S +G+ GS GQ S+ S G S +A H SG G+ HGSG GQ P
Sbjct: 837 HFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGR-----HGSGSGQSP 891
Query: 577 GDG-HGSGGGKN-SGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQ 624
G G GSG G++ S G GSGSG+ S G G + S FG + S Q
Sbjct: 892 GHGQRGSGSGQSPSYGRHGSGSGR-SSSSGRHGSGSGQSSGFGHKSSSGQ 940
Score = 82.4 bits (202), Expect = 2e-15
Identities = 72/205 (35%), Positives = 89/205 (43%), Gaps = 30/205 (14%)
Query: 418 RGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGK 477
RG R R + +S+ + + S H + + S GSGSG+ G
Sbjct: 269 RGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHG----- 323
Query: 478 EDQEGSGGDYM-PMNNWGSGNGRGSGGGQGSNGQGSSS----HSSGGNQCSGEGQ-GSRG 531
Q GSG Y ++ SG+G+ SG GQ +G G SS H SG S +GQ GS
Sbjct: 324 --QHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTS 381
Query: 532 GQGSNG--QGSGGNQCSRDGQGTA--------GGHGSGGGQRPGGGH-GSGGGQGPGDGH 580
GQ S+ GS Q S GQ + G H SG GQ PG G GSG GQ P G
Sbjct: 382 GQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQ 441
Query: 581 ---GSGGGKNSG---GGKGSGSGKG 599
G G +SG G G SG G
Sbjct: 442 HGTGFGRSSSSGPYVSGSGYSSGFG 466
Score = 81.6 bits (200), Expect = 4e-15
Identities = 68/184 (36%), Positives = 90/184 (48%), Gaps = 21/184 (11%)
Query: 452 NGARLSSEVSGSGSG---NFGEEGNPQGK---EDQEGSGGDYMP---MNNWGSGNGRGSG 502
+G SE GS SG ++G+ G+ + Q GSG P GSG+G+ S
Sbjct: 964 SGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1023
Query: 503 GGQGSNGQGSSS----HSSGGNQCSGEG-QGSRGGQGSNGQGSGGNQCSRDGQGTAGGHG 557
G +G G SS + SG SG G + SR GQ S G G + S T G HG
Sbjct: 1024 YGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS---GYGQHGSSSGHSSTHGQHG 1080
Query: 558 SGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSG-GGKGSGSGKGSDGDGERGKSLKKRS 614
S GQ G HG+ GQ G HGSG ++SG G +GSGSG+ S G G+RG ++
Sbjct: 1081 STSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ-SPGHGQRGSGSRQSP 1139
Query: 615 YFGK 618
+G+
Sbjct: 1140 SYGR 1143
Score = 81.3 bits (199), Expect = 5e-15
Identities = 71/224 (31%), Positives = 94/224 (41%), Gaps = 36/224 (16%)
Query: 437 APSPARPRHPAEAPNNGA----RLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNN 492
+PSP+R RH + + + + R S S S G+ G +E G
Sbjct: 1006 SPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 1065
Query: 493 WGSGNGRGSGGGQGSNGQGSSS----HSSGGNQCSGEGQGSRGGQGSNG---QGSGGNQC 545
GS +G S GQ + G SS H + Q S GQ G S+G QGSG Q
Sbjct: 1066 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 1125
Query: 546 SRDGQGTAGG--------HGSGGGQRPGGG-HGSGGGQGPGDGH--------------GS 582
GQ +G HGSG G+ G HGSG G+ G GH GS
Sbjct: 1126 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 1185
Query: 583 GGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
G G +SG G+ GS SG+ S G+ G S S++G+ +Q
Sbjct: 1186 GSGHSSGYGQHGSRSGQSSRGE-RHGSSSGSSSHYGQHGSGSRQ 1228
Score = 81.3 bits (199), Expect = 5e-15
Identities = 71/213 (33%), Positives = 91/213 (42%), Gaps = 45/213 (21%)
Query: 448 EAPNNGARLSSEVSGSGSG---NFGEEGNPQGKEDQEG----------SGGDYMPMNNWG 494
E + G S GSGS ++G++G+ G+ G S G + + W
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 2325
Query: 495 SGNGR-GSGGGQGS----------NGQGSSSHSSG-GNQCSGEGQGSRGGQGSNGQGSGG 542
S +GR GSG GQ S G + H SG G+ S E GSR GQ S G+ G
Sbjct: 2326 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGS 2385
Query: 543 NQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGGQGPGDG---HGSGGGKNS-----GGGKG 593
S + G HGSG Q G G HGSG GQ P HGSG G++S G G G
Sbjct: 2386 ---SSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSG 2442
Query: 594 SGSGKG--------SDGDGERGKSLKKRSYFGK 618
S +G S G G R + S +G+
Sbjct: 2443 WSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2475
Score = 80.9 bits (198), Expect = 7e-15
Identities = 71/201 (35%), Positives = 83/201 (41%), Gaps = 33/201 (16%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNN-WGSGNGRGSGGGQGSNGQGSSS- 514
SS S S G G ++GSG + P GSG G S GQ +G G SS
Sbjct: 1211 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 1270
Query: 515 ----------------HSSGGNQCS-----GEGQGSRGGQGSNGQGSGGNQC-----SRD 548
H SG S G G G QG +G SG + S
Sbjct: 1271 RGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1330
Query: 549 GQGTAGGH-GSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGSDGDG 604
GQ ++ GH GSG Q G G HG+G GQ P G HGSG G +S G+ GSGSG S G
Sbjct: 1331 GQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSG-WSSSSG 1389
Query: 605 ERGKSLKKRSYFGKLTQSKQQ 625
G + S FG S Q
Sbjct: 1390 RHGSGSGQSSGFGHHESSSWQ 1410
Score = 80.9 bits (198), Expect = 7e-15
Identities = 93/310 (30%), Positives = 123/310 (39%), Gaps = 49/310 (15%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSG-GDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSG-G 519
GSGSG +P + GSG G + +GSG+G S G +G SSHSSG G
Sbjct: 1470 GSGSGQ-----SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG---SSHSSGLG 1521
Query: 520 NQCSGEGQGSRGGQGSNGQGSG-----GNQCSRDGQGTA--------------GGHGSGG 560
++ S GQ S G G +G SG G S GQ ++ G HGSG
Sbjct: 1522 HRESRSGQSS--GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 1579
Query: 561 GQRPG-GGHGSGGGQGPGDGHGSGGGKNSG--GGKGSGSGKGSDGDGERGKSLKKRSYFG 617
Q G G GSG GQ PG G G + S G GSGSG+ S G+ G L + S FG
Sbjct: 1580 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR-SSSSGQHGSGLGESSGFG 1638
Query: 618 KLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAE 677
S Q +G + G G+ G R RG + +
Sbjct: 1639 HHESSSGQS----SSYSQHGSGSGHSSGYGQHGSRSGQ---SSRGERHGSSSRSSSRYGQ 1691
Query: 678 IPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPF 737
G+ + R + P R + L SS + Q+ S S + SR P+
Sbjct: 1692 HGSGSRQSSGHGR---QGSGSGQSPSRGRHGSGLGHSSSH----GQHGSGSGRSSSRGPY 1744
Query: 738 EDSRGYMMMF 747
E G+ +F
Sbjct: 1745 ESRSGHSSVF 1754
Score = 80.9 bits (198), Expect = 7e-15
Identities = 63/183 (34%), Positives = 75/183 (40%), Gaps = 26/183 (14%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR-GSGGGQGSN----------GQ 510
GSGSG G S G + + W S +GR GSG GQ S
Sbjct: 1823 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 511 GSSSHSSG-GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGG----------HGSG 559
G + H SG G+ S E GSR GQ S G+ G + S G G HGSG
Sbjct: 1883 GYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSG 1942
Query: 560 GGQRPG---GGHGSGGGQGPGDG-HGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSY 615
GQ P G HGSG GQ G +GSG G +S G S G G R + S
Sbjct: 1943 SGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
Query: 616 FGK 618
+G+
Sbjct: 2003 YGQ 2005
Score = 80.5 bits (197), Expect = 9e-15
Identities = 117/479 (24%), Positives = 163/479 (34%), Gaps = 85/479 (17%)
Query: 437 APSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEG-------NPQGKEDQEGSGGDYMP 489
+PSP+R RH + +G S GSGSG G + G +E G
Sbjct: 1946 SPSPSRGRHGS---GSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
Query: 490 MNNWGSGNGRGSGGGQGSNGQGSSS----HSSGGNQCSGEGQGSRGGQGSNG---QGSGG 542
GS +G S GQ + G SS H + Q S GQ G S+G QGSG
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2062
Query: 543 NQCSRDGQGTAGG--------HGSGGGQRPGGG-HGSGGGQGPGDGH------------- 580
Q GQ +G HGSG G+ G HG G G+ G GH
Sbjct: 2063 GQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQ 2122
Query: 581 -GSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPP 638
GSG G +SG G+ GS SG+ S G+ G S S +G+ +Q
Sbjct: 2123 HGSGSGHSSGYGQHGSRSGQSSRGE-RHGSSSGSSSRYGQHGSGSRQ------------- 2168
Query: 639 PAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDD 698
+ G G +G G G+ + + ++RGP+ +R+
Sbjct: 2169 -SSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS--GRSSSRGPYESRS------- 2218
Query: 699 PYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSP 758
V S S + Q+ S S S+ + G F + S
Sbjct: 2219 ----GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS- 2273
Query: 759 PKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSS 818
++ + S Y G+G P R+ G S S+ + S SS
Sbjct: 2274 -----SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGS--GSGWSS 2326
Query: 819 PLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPS 877
G++ + G G S +W SG G S GS S S
Sbjct: 2327 SSGRHGS--------GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS 2377
Score = 80.1 bits (196), Expect = 1e-14
Identities = 68/176 (38%), Positives = 83/176 (47%), Gaps = 21/176 (11%)
Query: 444 RHPAEAPNNGARLSSEVSGSG-SGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSG 502
RH A + + +R SGSG S ++G+ G+ G G G GSG G G
Sbjct: 1351 RHGAGSGQSPSR-GRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS-------GSGQSSGFG 1402
Query: 503 GGQGSNGQ--GSSSHSSG-GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG 559
+ S+ Q G + H SG G+ S E GSR GQ S G+ G S + G HGSG
Sbjct: 1403 HHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGS---SSGSSSSYGQHGSG 1459
Query: 560 GGQRPG-GGHGSGGGQGPGDG---HGSGGGKNSG-GGKGSGSG-KGSDGDGERGKS 609
Q G G HGSG GQ P HGSG G++S GSGSG S G E G S
Sbjct: 1460 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSS 1515
Score = 79.7 bits (195), Expect = 2e-14
Identities = 63/177 (35%), Positives = 79/177 (44%), Gaps = 23/177 (12%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPM---NNWGSGNGRGSGGGQGSNGQGSS 513
SS S S G G Q GSG P GSG+G+ S G +G G S
Sbjct: 1915 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWS 1974
Query: 514 S----HSSGGNQCSGEGQ-----GSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRP 564
S + SG SG G G G G +G SG + T G HGS GQ
Sbjct: 1975 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHS-------STHGQHGSASGQSS 2027
Query: 565 G-GGHGSGGGQGPGDG-HGSGGGKNSG-GGKGSGSGKGSDGDGERGKSLKKRSYFGK 618
G HG+ GQ G HGSG ++SG G +GSGSG+ S G G+RG ++ +G+
Sbjct: 2028 SCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ-SPGHGQRGSGSRQSPSYGR 2083
Score = 79.3 bits (194), Expect = 2e-14
Identities = 65/193 (33%), Positives = 79/193 (40%), Gaps = 31/193 (16%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSG-----GDYMPMNNWGSGNGR-GSGGGQGSN-- 508
SS+ SG G G +P GSG G + + W S +GR GSG GQ S
Sbjct: 1343 SSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402
Query: 509 --------GQGSSSHSSG-GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGG---- 555
G + H SG G+ S E GSR GQ S G+ G + S G G
Sbjct: 1403 HHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQ 1462
Query: 556 ------HGSGGGQRPG---GGHGSGGGQGPG-DGHGSGGGKNSGGGKGSGSGKGSDGDGE 605
HGSG GQ P G HGSG GQ +GSG G +S G S G G
Sbjct: 1463 SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGH 1522
Query: 606 RGKSLKKRSYFGK 618
R + S +G+
Sbjct: 1523 RESRSGQSSGYGQ 1535
Score = 79.3 bits (194), Expect = 2e-14
Identities = 75/218 (34%), Positives = 92/218 (42%), Gaps = 22/218 (10%)
Query: 418 RGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGK 477
RG R + + + + + S H + +G S GSGSG+ G
Sbjct: 2145 RGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSG 2204
Query: 478 EDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSS----HSSG-GNQCSGEGQGSRGG 532
+ S G Y S +G S GQ +G G SS H SG G+ CS GS G
Sbjct: 2205 SGRSSSRGPYE------SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 2258
Query: 533 QGS--NGQGSGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNS 588
Q S + +GS Q S GQ HGSG Q G GSG GQ P G HGSG G +S
Sbjct: 2259 QSSTFDQEGSSTGQSSSHGQ-----HGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 2313
Query: 589 GGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
G+ GSGSG S G G + S FG S Q
Sbjct: 2314 SYGQHGSGSG-WSSSSGRHGSGSGQSSGFGHHESSSWQ 2350
Score = 79.0 bits (193), Expect = 3e-14
Identities = 71/211 (33%), Positives = 88/211 (41%), Gaps = 39/211 (18%)
Query: 439 SPARPRHPA---EAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGS 495
S R +H + ++P +G R GSGSG G + S G Y+ + + S
Sbjct: 410 SSGRGQHSSGSGQSPGHGQR------GSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSS 463
Query: 496 GNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQ-GSRGGQGSNG--QGSGGNQCSRDGQGT 552
G G + S+G + H SG SG GQ GSR GQ S G QGS S GQ
Sbjct: 464 GFGHHESSSEHSSGY--TQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHG 521
Query: 553 AGG--------HGSGGGQRPG---GGHGSGGGQGPGDG-HGSGGGKNSGGG---KGSGSG 597
+G HGSG GQ P G H SG Q G HG G G++S G GSG
Sbjct: 522 SGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHS 581
Query: 598 KG----------SDGDGERGKSLKKRSYFGK 618
G S G G+ G S S G+
Sbjct: 582 SGLGHQESRSGQSSGYGQHGSSSGHSSTHGQ 612
Score = 79.0 bits (193), Expect = 3e-14
Identities = 69/174 (39%), Positives = 84/174 (48%), Gaps = 18/174 (10%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGS-GGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
GSGSG+F +G Q GS G + GS G+ S GQ +G GSS SS G
Sbjct: 2241 GSGSGHFCSQG-------QHGSTSGQSSTFDQEGSSTGQSSSHGQ--HGSGSSQSSSYGQ 2291
Query: 521 QCSGEGQG-SRG--GQGSNGQGSGGNQCSRDGQGTAGG-HGSGGGQRPG-GGHGSGGGQG 575
Q SG GQ SRG G GS S G S G ++ G HGSG GQ G G H S Q
Sbjct: 2292 QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 2351
Query: 576 PG-DGHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQM 627
G HGSG G +S + GS SG+ S G+ G S S +G+ +Q +
Sbjct: 2352 SGYTQHGSGSGHSSSYEQHGSRSGQSSRGE-RHGSSSGSSSSYGQHGSGSRQSL 2404
Score = 79.0 bits (193), Expect = 3e-14
Identities = 63/162 (38%), Positives = 83/162 (51%), Gaps = 23/162 (14%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSG-GDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSG-G 519
GSGSG +P + GSG G + +GSG+G S G +G G HSSG G
Sbjct: 2410 GSGSGQ-----SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSG---HSSGLG 2461
Query: 520 NQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGGQGPGD 578
++ S GQ S G G +G SG + T G HGS GQ G HG+ GQ
Sbjct: 2462 HRESRSGQSS--GYGQHGSSSGHS-------STHGQHGSTSGQSSSCGQHGASSGQSSSH 2512
Query: 579 G-HGSGGGKNSG-GGKGSGSGKGSDGDGERGKSLKKRSYFGK 618
G HGSG ++SG G +GSGSG+ S G G+RG ++ +G+
Sbjct: 2513 GQHGSGSSQSSGYGRQGSGSGQ-SPGHGQRGSGSRQSPSYGR 2553
Score = 78.2 bits (191), Expect = 5e-14
Identities = 76/221 (34%), Positives = 92/221 (41%), Gaps = 45/221 (20%)
Query: 437 APSPARPRHPAEAPNNGARLSSEVS--GSGSGNFGEEG-------NPQGKEDQEGSGGDY 487
+PSP+R RH +G+R SS G GSG G + G QE G
Sbjct: 540 SPSPSRGRH-----ESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQS 594
Query: 488 MPMNNWGSGNGRGSGGGQ------------------------GSNGQGSSSHSSGGNQCS 523
GS +G S GQ G +G GSS S G Q S
Sbjct: 595 SGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGS 654
Query: 524 GEGQG-SRGGQGSN--GQGSGGNQCSRDGQGTAGG-HGSGGGQRPGGGHGSGGGQGPG-D 578
G GQ SRG GS+ S G S G ++ G HGS GQ G GH SG GQ G
Sbjct: 655 GSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 579 GHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGK 618
HGSG +SG K GS SG+ S + + G S S +G+
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSE-QHGSSSGLSSSYGQ 754
Score = 78.2 bits (191), Expect = 5e-14
Identities = 58/157 (36%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR-GSGGGQ----GSNGQGSSSHS 516
GS SG G Q S G + ++ SG GR GSG GQ G G GS
Sbjct: 1080 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 1139
Query: 517 SGGNQCSGEGQGSRGGQGSNGQGSG---GNQCSRDGQGTA-GGHGSGGGQRPG-GGHGSG 571
S G SG G+ S GQ +G G G+ S GQ ++ HGSG G G G HGS
Sbjct: 1140 SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1199
Query: 572 GGQGP-GDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
GQ G+ HGS G +S G+ + S G G +G
Sbjct: 1200 SGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG 1236
Score = 78.2 bits (191), Expect = 5e-14
Identities = 67/176 (38%), Positives = 86/176 (48%), Gaps = 22/176 (12%)
Query: 462 GSGSGNF---GEEGNPQGKE---DQEGSG-GDYMPMNNWGSGNGRGSGGGQGSNGQGSSS 514
GSGSG+F G+ G+ G+ DQEGS G + GSG+ + SG G+ +G GS
Sbjct: 1301 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGR--HGAGSGQ 1358
Query: 515 HSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGG 573
S G SG G S GQ +G GSG + S G HGSG GQ G G H S
Sbjct: 1359 SPSRGRHGSGSGHSSSYGQ--HGSGSGWSSSS-------GRHGSGSGQSSGFGHHESSSW 1409
Query: 574 QGPG-DGHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQM 627
Q G HGSG G +S + GS SG+ S G+ G S S +G+ +Q +
Sbjct: 1410 QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGE-RHGSSSGSSSSYGQHGSGSRQSL 1464
Score = 78.2 bits (191), Expect = 5e-14
Identities = 58/157 (36%), Positives = 71/157 (45%), Gaps = 11/157 (7%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR-GSGGGQ----GSNGQGSSSHS 516
GS SG G Q S G + ++ SG GR GSG GQ G G GS
Sbjct: 2490 GSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP 2549
Query: 517 SGGNQCSGEGQGSRGGQGSNGQGSG---GNQCSRDGQGTA-GGHGSGGGQRPG-GGHGSG 571
S G SG G+ S GQ +G G G+ S GQ ++ HGSG G G G HGS
Sbjct: 2550 SYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2609
Query: 572 GGQGP-GDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
GQ G+ HGS G +S G+ + S G G +G
Sbjct: 2610 SGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG 2646
Score = 77.8 bits (190), Expect = 6e-14
Identities = 66/170 (38%), Positives = 76/170 (44%), Gaps = 34/170 (20%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGS-GGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
GSGSG+F +G Q GS G + GS G+ S GQ +G GSS SS G
Sbjct: 1771 GSGSGHFCSQG-------QHGSTSGQSSTFDQEGSSTGQSSSHGQ--HGSGSSQSSSYGQ 1821
Query: 521 QCSGEGQG-SRG--GQGSNGQGSGGNQCSRDGQGTAGG-HGSGGGQRPGGGH-------- 568
Q SG GQ SRG G GS S G S G ++ G HGSG GQ G GH
Sbjct: 1822 QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQS 1881
Query: 569 ------GSGGGQGPG-DGHGSGGGKNS-----GGGKGSGSGKGSDGDGER 606
GSG G + HGS G++S G GS S G G G R
Sbjct: 1882 SGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSR 1931
Score = 76.6 bits (187), Expect = 1e-13
Identities = 75/234 (32%), Positives = 98/234 (41%), Gaps = 65/234 (27%)
Query: 442 RPRHPA---EAPNNGARLSSEVSGSGSG---NFGEEGNPQGKEDQEGSGGDYMPMNNWGS 495
R RH + ++P +G R GSGSG ++G G+ G+ G GS
Sbjct: 880 RGRHGSGSGQSPGHGQR------GSGSGQSPSYGRHGSGSGRSSSSG---------RHGS 924
Query: 496 GNGRGSG-GGQGSNGQGS--SSHSSG-GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQG 551
G+G+ SG G + S+GQ S + H SG G+ S E GSR GQ S + G + S G
Sbjct: 925 GSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG 984
Query: 552 TAGG----------HGSGGGQRPG---GGHGSGGGQ-----------------GP---GD 578
G HGSG GQ P G HGSG GQ GP G
Sbjct: 985 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGS 1044
Query: 579 GHGSG-------GGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
GH SG G++SG G+ S S G+ G + + S G+ S Q
Sbjct: 1045 GHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQ 1098
Score = 75.5 bits (184), Expect = 3e-13
Identities = 68/194 (35%), Positives = 81/194 (41%), Gaps = 38/194 (19%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNN-WGSGNGRGSGGGQGSNGQGSSS- 514
SS S S G G ++GSG P GSG G S GQ +G G SS
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 2680
Query: 515 ----------------HSSGGNQCS-----GEGQGSRGGQGSNGQGSGGNQC-----SRD 548
H SG S G G G QG +G SG + S
Sbjct: 2681 RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740
Query: 549 GQGTAGGH-GSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSGGGK-GSGSGKGS---- 600
GQ ++ GH GSG Q G G HG+G GQ G HGSG G++S G+ GSGSG+ S
Sbjct: 2741 GQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQ 2800
Query: 601 --DGDGERGKSLKK 612
G G+ G S K
Sbjct: 2801 HGSGSGQDGYSYCK 2814
Score = 75.1 bits (183), Expect = 4e-13
Identities = 83/260 (31%), Positives = 105/260 (40%), Gaps = 85/260 (32%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNW----- 493
SP+R RH + +G S GSGSG G G + SG + ++W
Sbjct: 1359 SPSRGRHGS---GSGHSSSYGQHGSGSGWSSSSGR-HGSGSGQSSGFGHHESSSWQSSGC 1414
Query: 494 ---GSGNGR-------GSGGGQGSNGQ------GSSS----HSSGGNQCSGEGQ-GSRGG 532
GSG+G GS GQ S G+ GSSS H SG Q G GQ GS G
Sbjct: 1415 TQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG 1474
Query: 533 Q------GSNGQGSG-------------------------------GNQCSRDGQ----- 550
Q G +G GSG G++ SR GQ
Sbjct: 1475 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG 1534
Query: 551 ---------GTAGGHGSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSG-GGKGSGSGK 598
T G HGS GQ G HG+ GQ G HGSG ++SG G +GSGSG+
Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 1594
Query: 599 GSDGDGERGKSLKKRSYFGK 618
S G G+RG ++ +G+
Sbjct: 1595 -SPGHGQRGSGSRQSPSYGR 1613
Score = 74.7 bits (182), Expect = 5e-13
Identities = 67/181 (37%), Positives = 80/181 (44%), Gaps = 21/181 (11%)
Query: 448 EAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPM-NNWGSGNGRGSGGGQG 506
++ + G S+ SG G G Q GSG P GSG+GR S G+
Sbjct: 863 QSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRH 922
Query: 507 SNGQGSSS---HSSGGNQCSGEGQ-GSRGGQGSNGQ--GSGGNQCSRDGQ-GTAGGHGS- 558
+G G SS H S Q SG Q GS G S+ + GS Q SR Q G++ G S
Sbjct: 923 GSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSS 982
Query: 559 ----GGGQRPG---GGHGSGGGQGPGDG---HGSGGGKNSG-GGKGSGSG-KGSDGDGER 606
G G R G HGSG GQ P HGSG G++S G SGSG S G E
Sbjct: 983 YGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYES 1042
Query: 607 G 607
G
Sbjct: 1043 G 1043
Score = 74.3 bits (181), Expect = 7e-13
Identities = 63/186 (33%), Positives = 76/186 (40%), Gaps = 34/186 (18%)
Query: 451 NNGARLSSEVSGSGS----GNFGEEGNPQGKEDQEGSG-------GDYMPMNNWGSGNGR 499
+ +R + SGSG G G + Q GSG G + ++ SG G
Sbjct: 644 SQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGH 703
Query: 500 GSGGGQGSNGQGSSSHSSGGNQCSG-EGQGSRGGQGSNGQ--GSGGNQCSRDGQGTAGGH 556
SG GQ S G S H SG + SG GSR GQ S + GS S GQ +G H
Sbjct: 704 KSGSGQSS---GYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSH 760
Query: 557 GSGGGQRPGGG---------HGSGGGQGPGDG-HGSG-------GGKNSGGGKGSGSGKG 599
S G R G G HGS G G HGSG G SG G+ SG G+
Sbjct: 761 QSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQH 820
Query: 600 SDGDGE 605
G G+
Sbjct: 821 ESGSGQ 826
Score = 73.6 bits (179), Expect = 1e-12
Identities = 58/163 (35%), Positives = 73/163 (44%), Gaps = 20/163 (12%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQ 521
GSGSG+ +G Q S G + + S G+ + S+G+G HSSG Q
Sbjct: 365 GSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQ--HSSGSGQ 422
Query: 522 CSGEGQ-GSRGGQG-SNGQ-GSGGNQCSRDGQGTAG-GHGSGGGQRPGGG--------HG 569
G GQ GS GQ S+GQ G+G + S G +G G+ SG G HG
Sbjct: 423 SPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHG 482
Query: 570 SGGGQGPGDG-HGSGGGKNS-----GGGKGSGSGKGSDGDGER 606
SG G G G HGS G++S G GS S G G G R
Sbjct: 483 SGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSR 525
Score = 73.2 bits (178), Expect = 1e-12
Identities = 58/167 (34%), Positives = 79/167 (47%), Gaps = 22/167 (13%)
Query: 462 GSGSGN---FGEEGNPQGK----EDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSS 514
GSGSG+ +G+ G+ G+ E S G GSG+ + G G+ QGS S
Sbjct: 248 GSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGR----QGSGS 303
Query: 515 HSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGG 573
S + G G G G +G GS + + G + SG GQ G G H SG G
Sbjct: 304 RQSPSHVRHGSGSGHSSSHGQHGSGSSYSY-------SRGHYESGSGQTSGFGQHESGSG 356
Query: 574 QGPG-DGHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGK 618
Q G HGSG G +S G+ GS SG+ S G+ G S ++ S +G+
Sbjct: 357 QSSGYSKHGSGSGHSSSQGQHGSTSGQAS-SSGQHGSSSRQSSSYGQ 402
Score = 72.8 bits (177), Expect = 2e-12
Identities = 81/290 (27%), Positives = 105/290 (36%), Gaps = 53/290 (18%)
Query: 392 EMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPN 451
E F+ + E ++SR R L G S +S SF R S + ++ +
Sbjct: 124 ESSFSHSSWSAGENDSYSRNVRGSLKPGTES---ISRRLSFQRDF--SGQHNSYSGQSSS 178
Query: 452 NGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNW-GSGNGRGSGGGQGSNGQ 510
G + S SG G G Q GSG N+ GSG+G+ SG Q +
Sbjct: 179 YGEQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSS 238
Query: 511 GSSSHSSGGNQCSGEGQGSRGGQGSNGQGSG------GNQCSRDGQGTAGGHGSGGGQRP 564
G SS G G G G G G +G SG ++ S + G HGSG Q
Sbjct: 239 GQSS----GYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSL 294
Query: 565 GGG--------------HGSGGGQGPGDG-HGSG-------GGKNSGGGKGSGSGKGSDG 602
G G HGSG G G HGSG G SG G+ SG G+ G
Sbjct: 295 GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESG 354
Query: 603 DGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGR 652
G+ K S G + Q G T G+ S G+
Sbjct: 355 SGQSSGYSKHGSGSGHSSSQGQH---------------GSTSGQASSSGQ 389
Score = 72.4 bits (176), Expect = 3e-12
Identities = 61/183 (33%), Positives = 77/183 (42%), Gaps = 22/183 (12%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMN-NWGSGNGRGSGGGQGSNGQGSS-- 513
SS S S G G ++GSG P + GSG+G S GQ +G S
Sbjct: 275 SSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYS 334
Query: 514 --SHSSGGNQCSGEGQGSRGGQGSNG---QGSGGNQCSRDGQGTAGGHGSGGGQRPGGG- 567
+ SG Q SG GQ G S+G GSG S GQ HGS GQ G
Sbjct: 335 RGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQ-----HGSTSGQASSSGQ 389
Query: 568 HGSGGGQGPGDG-------HGSGGGK-NSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKL 619
HGS Q G H SG G+ +SG G+ G G+ G G+ S + + FG+
Sbjct: 390 HGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRS 449
Query: 620 TQS 622
+ S
Sbjct: 450 SSS 452
Score = 71.6 bits (174), Expect = 4e-12
Identities = 67/202 (33%), Positives = 85/202 (42%), Gaps = 24/202 (11%)
Query: 418 RGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGK 477
RG R + + + + + S H + +G S GSG G+ G
Sbjct: 2615 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 2674
Query: 478 EDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSS----HSSG-GNQCSGEGQGSRGG 532
+ S G Y S G S GQ +G G SS H SG G+ CS GS G
Sbjct: 2675 SGRSSSRGPYE------SRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSG 2728
Query: 533 QGS--NGQGSGGNQCSRDGQGTAGG--------HGSGGGQRPGGG-HGSGGGQGPGDG-H 580
Q S + +GS Q S G +G HG+G GQ G HGSG GQ G H
Sbjct: 2729 QSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQH 2788
Query: 581 GSGGGKNSGGGKGSGSGKGSDG 602
GSG G++SG + GSG G DG
Sbjct: 2789 GSGSGQSSGYSQ-HGSGSGQDG 2809
Score = 70.9 bits (172), Expect = 7e-12
Identities = 75/221 (33%), Positives = 94/221 (42%), Gaps = 46/221 (20%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNW----- 493
SP+R RH + +G S GSGSG G G + SG + ++W
Sbjct: 1829 SPSRGRHGS---GSGHSSSYGQHGSGSGWSSSSGR-HGSGSGQSSGFGHHESSSWQSSGY 1884
Query: 494 ---GSGNGR-------GSGGGQGSNGQ--GSSSHSSGGNQCSGEGQGSRGGQGSNGQGSG 541
GSG+G GS GQ S G+ GSSS SS G G G G +G GSG
Sbjct: 1885 TQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG 1944
Query: 542 -------GNQCSRDGQGTA-GGHGSGGG-------QRPGGGHGSG-------GGQGPGDG 579
G S GQ ++ G +GSG G G GH SG GQ G G
Sbjct: 1945 QSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2004
Query: 580 -HGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSYFGK 618
HGS G +S G+ GS SG+ S G+ G S + S G+
Sbjct: 2005 QHGSSSGHSSTHGQHGSASGQ-SSSCGQHGASSGQSSSHGQ 2044
Score = 70.5 bits (171), Expect = 1e-11
Identities = 73/230 (31%), Positives = 90/230 (39%), Gaps = 41/230 (17%)
Query: 409 SRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNF 468
S RG H R S R + + + S H + +G S GSG G+
Sbjct: 1673 SSRGERHGSSSRSSSR-------YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS 1725
Query: 469 GEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSS----HSSG-GNQCS 523
G + S G Y S +G S GQ +G G SS H SG G+ CS
Sbjct: 1726 SSHGQHGSGSGRSSSRGPYE------SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCS 1779
Query: 524 GEGQGSRGGQGS--NGQGSGGNQCSRDGQGTAGG--------HGSGGGQRP-------GG 566
GS GQ S + +GS Q S GQ +G GSG GQ P G
Sbjct: 1780 QGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGS 1839
Query: 567 GHGSGGGQGPGDGHGSGGGKNSGGGK-GSGSGKGSDGDGERGKSLKKRSY 615
GH S GQ HGSG G +S G+ GSGSG+ S S + Y
Sbjct: 1840 GHSSSYGQ-----HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGY 1884
Score = 69.7 bits (169), Expect = 2e-11
Identities = 74/198 (37%), Positives = 92/198 (46%), Gaps = 35/198 (17%)
Query: 452 NGARLSSEVSGSGSGNFGEEGNPQGKEDQEGS--GGDYMPMNNWGSGNGRGSGGGQGSNG 509
+G+R S S GSG+ G+ +P + GS Y P G G+GR S G +G
Sbjct: 522 SGSRQSLGHSRHGSGS-GQSPSPSRGRHESGSRQSSSYGPH---GYGSGRSSSRGPYESG 577
Query: 510 QGSSSHSSG-GNQCSGEGQGSRGGQGSNGQGSG-----GNQCSRDGQGTA-GGHGSGGGQ 562
G HSSG G+Q S GQ S G G +G SG G S GQ ++ G HG+ GQ
Sbjct: 578 SG---HSSGLGHQESRSGQSS--GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQ 632
Query: 563 RPG-GGHGSG-------GGQGPGDG-------HGSGGGKNSGGGK-GSGSGKGSDGDGER 606
G HGSG G QG G G HGS G +S G+ GSGSG S +G
Sbjct: 633 SSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSG-WSSSNGPH 691
Query: 607 GKSLKKRSYFGKLTQSKQ 624
G + S FG + S Q
Sbjct: 692 GSVSGQSSGFGHKSGSGQ 709
Score = 69.3 bits (168), Expect = 2e-11
Identities = 66/197 (33%), Positives = 83/197 (42%), Gaps = 41/197 (20%)
Query: 462 GSGSGN---FGEEGNPQGK----EDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSS- 513
GSGSG+ G+ G+ G+ E Q S G GSG+ + G + +G G S
Sbjct: 482 GSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSP 541
Query: 514 -----SHSSGGNQCS-----GEGQGSRGGQGSNGQGSG-----GNQCSRDGQ-------- 550
H SG Q S G G G +G GSG G+Q SR GQ
Sbjct: 542 SPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHG 601
Query: 551 ------GTAGGHGSGGGQRPG-GGHGSGGGQGPGDG-HGSGGGKNSG-GGKGSGSGKGSD 601
T G HGS GQ G HG+ GQ G HGSG ++S G +GSGSG+ S
Sbjct: 602 SSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQ-SP 660
Query: 602 GDGERGKSLKKRSYFGK 618
G G S +G+
Sbjct: 661 SRGRHGSDFGHSSSYGQ 677
Score = 69.3 bits (168), Expect = 2e-11
Identities = 66/205 (32%), Positives = 83/205 (40%), Gaps = 28/205 (13%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGN---FGEE---GNPQGKEDQEGSGGDYMPMNN 492
SP+ RH + +G SS GSGSG FG + G G G
Sbjct: 903 SPSYGRHGS---GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQ 959
Query: 493 WGSGNGRGSGGGQGSNGQGSSS----HSSGGNQCSGEGQ-GSRGGQ------GSNGQGSG 541
GS +G+ S Q + GSSS H SG Q G GQ GS GQ G +G GSG
Sbjct: 960 HGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSG 1019
Query: 542 GNQCSRDGQGTAGGHGSGGGQRPGGGHGSG-------GGQGPGDG-HGSGGGKNSGGGKG 593
+ + +G S G G GH SG GQ G G HGS G +S G+
Sbjct: 1020 QSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1079
Query: 594 SGSGKGSDGDGERGKSLKKRSYFGK 618
+ S G+ G S + S G+
Sbjct: 1080 GSTSGQSSSCGQHGASSGQSSSHGQ 1104
Score = 69.3 bits (168), Expect = 2e-11
Identities = 61/179 (34%), Positives = 75/179 (41%), Gaps = 27/179 (15%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGK-------EDQEGSGGDYMPMN 491
SP+R RH + G S GSGSG G + + E G +
Sbjct: 2652 SPSRGRHGSGL---GHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYS 2708
Query: 492 NWGSGNGR-------GSGGGQGS--NGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSG- 541
GSG+G GS GQ S + +GSS+ S G G G G +G GSG
Sbjct: 2709 QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQ 2768
Query: 542 ----GNQCSRDGQGTA-GGHGSGGGQRPG-GGHGSGGGQGPGDGHGSGGGKNSGGGKGS 594
G S GQ ++ G HGSG GQ G HGSG GQ G + GG + GG GS
Sbjct: 2769 SLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQ-DGYSYCKGGSNHDGGSSGS 2826
Score = 68.9 bits (167), Expect = 3e-11
Identities = 71/220 (32%), Positives = 89/220 (40%), Gaps = 44/220 (20%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNW----- 493
SP+R RH + +G S GSGSG G G + SG + ++W
Sbjct: 2299 SPSRGRHGS---GSGHSSSYGQHGSGSGWSSSSGR-HGSGSGQSSGFGHHESSSWQSSGY 2354
Query: 494 ---GSGNGR-------GSGGGQGSNGQ------GSSS----HSSGGNQCSGEGQ-GSRGG 532
GSG+G GS GQ S G+ GSSS H SG Q G GQ GS G
Sbjct: 2355 TQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSG 2414
Query: 533 Q------GSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG-------GGQGPGDG 579
Q G +G GSG + +G S G G GH SG GQ G G
Sbjct: 2415 QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYG 2474
Query: 580 -HGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGK 618
HGS G +S G+ + S G+ G S + S G+
Sbjct: 2475 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 2514
Score = 68.9 bits (167), Expect = 3e-11
Identities = 71/214 (33%), Positives = 84/214 (39%), Gaps = 42/214 (19%)
Query: 448 EAPNNGARLSSEVSGSGSGNFGEE-GNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQG 506
++P+ G S S SG G G G E S G + GSG+G SG GQ
Sbjct: 2547 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 2606
Query: 507 SNGQGSSS-----------------HSSGGNQCSGEG-QGSRGGQG-SNGQ-GSGGNQCS 546
+ G SS H SG Q SG G QGS GQ S G+ GSG S
Sbjct: 2607 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSS 2666
Query: 547 RDGQGTAGGHGSGGGQRPG--------------GGHGSGGGQGPG-DGHGSGGGK-NSGG 590
GQ HGSG G+ G H SG G HGSG G S G
Sbjct: 2667 SHGQ-----HGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQG 2721
Query: 591 GKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQ 624
GS SG+ S D E + + SY + + S Q
Sbjct: 2722 QHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQ 2755
Score = 68.6 bits (166), Expect = 4e-11
Identities = 66/220 (30%), Positives = 84/220 (38%), Gaps = 49/220 (22%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSG-------GDYMPMN 491
SP+R RH ++ G S GSGSG + P G + SG G +
Sbjct: 659 SPSRGRHGSDF---GHSSSYGQHGSGSG-WSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS 714
Query: 492 NWGSGNGRGSG-------GGQGSNGQ---------------GSSSHSSGGNQCSGEGQG- 528
GSG+ SG GQ S + GS SH S G+ G G G
Sbjct: 715 QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGH 774
Query: 529 ---------SRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG-GGHGSGGGQGPGD 578
S G S+GQ G CS + G + SG GQ G G H SG GQG
Sbjct: 775 SPSRVRHGSSSGHSSSHGQHGSGTSCS----SSCGHYESGSGQASGFGQHESGSGQGYSQ 830
Query: 579 GHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGK 618
HGS G S G+ + S G+ S + S +G+
Sbjct: 831 -HGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQ 869
Score = 68.2 bits (165), Expect = 5e-11
Identities = 65/215 (30%), Positives = 80/215 (37%), Gaps = 44/215 (20%)
Query: 448 EAPNNGARLSSEVSGSGSGNFGEE-GNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQG 506
++P+ G S S SG G G G E S G + GSG+G SG GQ
Sbjct: 1137 QSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQH 1196
Query: 507 SNGQGSSS-----------------HSSGGNQCSGEG-QGSRGG----QGSNGQGSG--- 541
+ G SS H SG Q SG G QGS G +G +G G G
Sbjct: 1197 GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSS 1256
Query: 542 ---------GNQCSRDGQGTAGGHGSGGGQRPGGG--------HGSGGGQGPGDG-HGSG 583
G SR + GH S GQ G HGSG G G HGS
Sbjct: 1257 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 1316
Query: 584 GGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGK 618
G++S + S S G RG + S +G+
Sbjct: 1317 SGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGR 1351
Score = 65.1 bits (157), Expect = 4e-10
Identities = 67/210 (31%), Positives = 92/210 (43%), Gaps = 37/210 (17%)
Query: 445 HPAEAPNNGARLSSEVSGSG-SGNFGEEGNPQGKE---DQEGSG-------GDYMPMNNW 493
H + + S SGSG S +G+ G+ G+ ++ GS G + +
Sbjct: 2579 HHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ 2638
Query: 494 GSGNGR-GSGGGQ----GSNGQGSSSHSSGGNQCSGEGQGSRGGQ-----------GSNG 537
SG+GR GSG GQ G +G G SS G SG G+ S G G +
Sbjct: 2639 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHE 2698
Query: 538 QGSGGNQC-SRDGQGTA-----GGHGSGGGQRPG-GGHGSGGGQGPGDGH-GSGGGKNSG 589
GSG + S+ G G+ G HGS GQ GS GQ GH GSG ++SG
Sbjct: 2699 SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSG 2758
Query: 590 GGK-GSGSGKGSDGDGERGKSLKKRSYFGK 618
G+ G+GSG+ S G G + S +G+
Sbjct: 2759 YGRHGAGSGQ-SLSHGRHGSGSGQSSSYGQ 2787
Score = 60.5 bits (145), Expect = 1e-08
Identities = 60/189 (31%), Positives = 71/189 (37%), Gaps = 40/189 (21%)
Query: 452 NGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNG-RGSGGGQ----G 506
+G SS GS S G + G + + G+G RGSG GQ G
Sbjct: 381 SGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSG 440
Query: 507 SNGQGSSSHSSGGNQCSGEGQGS-----------RGGQGSNGQGSG-----GNQCSRDGQ 550
+G G SS G SG G S G +G GSG G SR GQ
Sbjct: 441 QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQ 500
Query: 551 GTA--------------GGHGSGGGQRPG-GGHGSGGGQGPGDG---HGSGGGKNSG-GG 591
+ G HGSG Q G HGSG GQ P H SG ++S G
Sbjct: 501 SSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGP 560
Query: 592 KGSGSGKGS 600
G GSG+ S
Sbjct: 561 HGYGSGRSS 569
Score = 44.7 bits (104), Expect = 6e-04
Identities = 42/120 (35%), Positives = 56/120 (46%), Gaps = 28/120 (23%)
Query: 462 GSGSGNF---GEEGNPQGKE---DQEGSG-GDYMPMNNWGSGNGRGSGGGQ--------- 505
GSGSG+F G+ G+ G+ DQEGS G + GSG+ + SG G+
Sbjct: 2711 GSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSL 2770
Query: 506 ------GSNGQGSS--SHSSGGNQCSGEGQ-GSRGGQGSNGQGSGGNQCSRDGQGTAGGH 556
+GQ SS H SG Q SG Q GS GQ GG+ + DG G++G +
Sbjct: 2771 SHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGS--NHDG-GSSGSY 2827
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 88.2 bits (217), Expect = 4e-17
Identities = 53/126 (42%), Positives = 59/126 (46%), Gaps = 7/126 (5%)
Query: 494 GSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTA 553
G G+ G G G GS G G SSGG G G GG G G G + G G
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYG 514
Query: 554 GGHGSGG-GQRPGGGHGSGGGQGPGDGHG---SGGGKNSGGGKGSGSGKG---SDGDGER 606
GG SGG G GG+G G G G G+G SGGG +SGGG G GS G S G
Sbjct: 515 GGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSV 574
Query: 607 GKSLKK 612
G+S K
Sbjct: 575 GESSSK 580
Score = 86.7 bits (213), Expect = 1e-16
Identities = 50/121 (41%), Positives = 60/121 (49%), Gaps = 3/121 (2%)
Query: 478 EDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNG 537
E + SGG ++G G G GS GG S G H GG+ G G GS GG S G
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGH--GGSSGGGYGGGSSGGGSSGG 511
Query: 538 QGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG-GGQGPGDGHGSGGGKNSGGGKGSGS 596
GG+ G ++GG+G G GGG+G G G G G G GGG +SGG K S S
Sbjct: 512 GYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSS 571
Query: 597 G 597
G
Sbjct: 572 G 572
Score = 70.9 bits (172), Expect = 7e-12
Identities = 53/138 (38%), Positives = 56/138 (40%), Gaps = 30/138 (21%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQ 521
G GS G G G SGG Y GS G SGGG G GSSS GG+
Sbjct: 474 GGGSSGGGSSGGGHGGGHGGSSGGGY----GGGSSGGGSSGGGYGG---GSSSGGHGGSS 526
Query: 522 CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHG 581
G G GS GG G G GG SGGG GGG+G G G GH
Sbjct: 527 SGGYGGGSSGG----------------GGGGYGGGSSGGGSSSGGGYGGGSSSG---GHK 567
Query: 582 SGGGKNSGGGKGSGSGKG 599
S +S G G S KG
Sbjct: 568 S----SSSGSVGESSSKG 581
Score = 68.9 bits (167), Expect = 3e-11
Identities = 52/147 (35%), Positives = 56/147 (38%), Gaps = 16/147 (10%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS 516
SS SG G G G G GG + S G G G GS S
Sbjct: 12 SSSRSGGGGGGGGC-----------GGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRG 60
Query: 517 SGGNQCSGEGQGSRGGQGSNGQGS-----GGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG 571
S G C G G GG G G GS G + G+ GG GGG GG G G
Sbjct: 61 SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGG 120
Query: 572 GGQGPGDGHGSGGGKNSGGGKGSGSGK 598
G G G G G GGG GG SG+ K
Sbjct: 121 GFGGGGFGGGFGGGFGGDGGLLSGNEK 147
Score = 68.2 bits (165), Expect = 5e-11
Identities = 45/111 (40%), Positives = 49/111 (44%), Gaps = 2/111 (1%)
Query: 494 GSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTA 553
G G G G GGG S SS S GG SG G +GS+G G G S G G
Sbjct: 20 GGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGG--SSGGYGGL 77
Query: 554 GGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDG 604
GG G G + G GG G G GS GG + GGG G G G G G
Sbjct: 78 GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFG 128
Score = 59.3 bits (142), Expect = 2e-08
Identities = 52/152 (34%), Positives = 63/152 (41%), Gaps = 11/152 (7%)
Query: 444 RHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG 503
R+ + + +R G G G G + + + GG + G RGS G
Sbjct: 4 RYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSG 63
Query: 504 GQGSNGQGSSSHSSGG-NQCSGEGQGS-RGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGG 561
G G SSGG G G GS RG GS+ GG+ G G+ GG GGG
Sbjct: 64 G------GCFGGSSGGYGGLGGFGGGSFRGSYGSS--SFGGSYGGSFGGGSFGGGSFGGG 115
Query: 562 QRPGGGHGSGG-GQGPGDGHGSGGGKNSGGGK 592
GGG G GG G G G G G GG SG K
Sbjct: 116 SFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEK 147
Score = 58.9 bits (141), Expect = 3e-08
Identities = 42/120 (35%), Positives = 47/120 (39%), Gaps = 14/120 (11%)
Query: 457 SSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS 516
SS SG G+ G G G GS G +G G+ G GG S G G S
Sbjct: 477 SSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSG 536
Query: 517 SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGP 576
GG G G GS GG S+G G GG S GGH S G G +GP
Sbjct: 537 GGG---GGYGGGSSGGGSSSGGGYGGGSSS-------GGHKSSS----SGSVGESSSKGP 582
Score = 53.1 bits (126), Expect = 2e-06
Identities = 45/122 (36%), Positives = 55/122 (45%), Gaps = 14/122 (11%)
Query: 487 YMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCS 546
Y ++ S G GGG G G G S +GS GG S+G SGG+
Sbjct: 5 YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLR-----ISSSKGSLGGGFSSGGFSGGSF-- 57
Query: 547 RDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGS-GKGSDGDGE 605
+G++GG GG GG+G GG G G GS G +S GG GS G GS G G
Sbjct: 58 --SRGSSGGGCFGGSS---GGYGGLGGFGGGSFRGSYGS-SSFGGSYGGSFGGGSFGGGS 111
Query: 606 RG 607
G
Sbjct: 112 FG 113
Score = 50.4 bits (119), Expect = 1e-05
Identities = 36/98 (36%), Positives = 42/98 (42%), Gaps = 2/98 (2%)
Query: 512 SSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG 571
S +SS + S G GG G G G + +G+ GG S GG GG S
Sbjct: 2 SVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGF--SGGSFSR 59
Query: 572 GGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKS 609
G G G GS GG GG G GS +GS G G S
Sbjct: 60 GSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGS 97
Score = 50.1 bits (118), Expect = 1e-05
Identities = 40/109 (36%), Positives = 48/109 (44%), Gaps = 10/109 (9%)
Query: 458 SEVSGSGSGNFGEEGNPQGKEDQEG--SGGDYMPMNNWGSGNGRGSGG-GQGSNGQGSSS 514
S G G G+ G G G G SGG Y ++ G G SGG G GS+G G
Sbjct: 482 SSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGG 541
Query: 515 HSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQR 563
+ G SG G S GG G G SGG++ S G + G S G R
Sbjct: 542 YGGGS---SGGGSSSGGGYG-GGSSSGGHKSSSSG---SVGESSSKGPR 583
Score = 44.7 bits (104), Expect = 6e-04
Identities = 32/89 (35%), Positives = 34/89 (38%), Gaps = 6/89 (6%)
Query: 529 SRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNS 588
SR G G G G GG G G + S GGG SGG G GS GG
Sbjct: 14 SRSGGGGGGGGCGG------GGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCF 67
Query: 589 GGGKGSGSGKGSDGDGERGKSLKKRSYFG 617
GG G G G G G S S+ G
Sbjct: 68 GGSSGGYGGLGGFGGGSFRGSYGSSSFGG 96
Score = 44.7 bits (104), Expect = 6e-04
Identities = 32/96 (33%), Positives = 36/96 (37%), Gaps = 6/96 (6%)
Query: 452 NGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQG 511
+G G SG G G G GG GS G G G G GS+G G
Sbjct: 491 HGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGG 550
Query: 512 SSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSR 547
SSS G G S GG S+ GS G S+
Sbjct: 551 SSSGGGYG------GGSSSGGHKSSSSGSVGESSSK 580
Score = 36.6 bits (83), Expect = 0.16
Identities = 29/87 (33%), Positives = 35/87 (40%), Gaps = 8/87 (9%)
Query: 451 NNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQ 510
++G S G GS + G G+ G SGG G G G GG G
Sbjct: 503 SSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGG-----GGGGYGGGSSGGGSSSGGGY 557
Query: 511 GSSSHSSGGNQCSGEGQGSRGGQGSNG 537
G S SSGG++ S GS G S G
Sbjct: 558 GGGS-SSGGHKSS--SSGSVGESSSKG 581
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 85.5 bits (210), Expect = 3e-16
Identities = 65/189 (34%), Positives = 87/189 (46%), Gaps = 23/189 (12%)
Query: 440 PARPRHPAEAPNNGARLSSEVSGS----GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGS 495
P + PA + +G+ SS S S SG++ ++ + G++ G Y P +G
Sbjct: 98 PGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQ 157
Query: 496 GN-------GRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRD 548
N G G GGG G+ GQ SS SSGG G G + G G +G G G
Sbjct: 158 QNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSG-GYGQQDRGGR 216
Query: 549 GQGTAGGHGSGGG---QRPGGGH---GSGGGQGPGDGHGSGGGKNSGGGK--GSGSGKGS 600
G+G +GG G GGG R GG+ G GGG+G G G GG + GG G +GS
Sbjct: 217 GRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRG---GRGGMGGSDRGGFNKFGGPRDQGS 273
Query: 601 DGDGERGKS 609
D E+ S
Sbjct: 274 RHDSEQDNS 282
Score = 75.1 bits (183), Expect = 4e-13
Identities = 62/185 (33%), Positives = 77/185 (41%), Gaps = 24/185 (12%)
Query: 448 EAPNNGARLSSEVSGSGS-GNFGEEGNPQGKEDQEGSGGDY----MPMNNWGS--GNGRG 500
++ N G S G GS G +G + Q Q+ S Y P + GS + +
Sbjct: 60 QSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQS 119
Query: 501 SGGGQGSNGQGSSSHSSGGNQCS-----------GEGQGSR--GGQGSNGQGSGGNQCSR 547
S GQ +G S S GG Q S G GQ ++ G G G GG +
Sbjct: 120 SSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQ 179
Query: 548 DGQGTAGGHGSGGG---QRPGGGHGSGG-GQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD 603
D + G GSGGG Q GG GSGG GQ G G GG GGG G G + S G
Sbjct: 180 DQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGY 239
Query: 604 GERGK 608
RG+
Sbjct: 240 EPRGR 244
Score = 56.2 bits (134), Expect = 2e-07
Identities = 50/163 (30%), Positives = 64/163 (39%), Gaps = 16/163 (9%)
Query: 500 GSGGGQGSN---GQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGH 556
G G Q S+ GQ S S S SG GQ S G + G Q + G G+ GG+
Sbjct: 22 GQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGY 81
Query: 557 GSGGGQRPGGGHGS---GGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKR 613
GS + G S G GQ P ++ G GS S S G + G ++
Sbjct: 82 GSSQSSQSSYGQQSSYPGYGQQPAP-------SSTSGSYGSSSQSSSYGQPQSGSYSQQP 134
Query: 614 SYFGKLTQSKQQQMPPPPP---PPPPPPPAGGTGGKGKSGGRF 653
SY G+ QQQ PP + G GG G GG +
Sbjct: 135 SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNY 177
Score = 55.1 bits (131), Expect = 4e-07
Identities = 52/159 (32%), Positives = 64/159 (40%), Gaps = 24/159 (15%)
Query: 477 KEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQG-- 534
+ D GG+ G GRG GG GS G G SGG G G R G
Sbjct: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGG---GGGGGQQRAGDWKC 428
Query: 535 -----SNGQGSGGNQCSR--------DGQGTAGGH--GSGGGQRPG--GGHGSGGGQG-P 576
N S N+C++ G G G H G+ G R G GG+ GG +G
Sbjct: 429 PNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRG 488
Query: 577 GDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSY 615
GD G GG+ G G G GK D GE + ++R Y
Sbjct: 489 GDRGGFRGGRGGGDRGGFGPGK-MDSRGEHRQDRRERPY 526
Score = 54.3 bits (129), Expect = 7e-07
Identities = 66/229 (28%), Positives = 83/229 (36%), Gaps = 67/229 (29%)
Query: 452 NGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQG 511
+G S++ SG G ++ G Q G G P G GS GG GS+
Sbjct: 39 SGYSQSTDTSGYGQSSYSSYGQSQNT----GYGTQSTPQ-------GYGSTGGYGSS--- 84
Query: 512 SSSHSSGGNQCSGEGQGSRGGQGS-NGQGSGGNQCSRDGQGTAGGHG---SGGGQRPGGG 567
SS SS G Q S G G + S +G +Q S GQ +G + S GGQ+
Sbjct: 85 QSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQS-- 142
Query: 568 HGSGGGQGPGDGHG--------SGGGKNSGGG-----------KGSGSGKG------SDG 602
+G P G+G SGGG GGG G GSG G S G
Sbjct: 143 YGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGG 202
Query: 603 DGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
G G + R G+ GG+GG G GG
Sbjct: 203 GGSGGYGQQDRGGRGR----------------------GGSGGGGGGGG 229
Score = 53.9 bits (128), Expect = 9e-07
Identities = 67/240 (27%), Positives = 85/240 (35%), Gaps = 65/240 (27%)
Query: 480 QEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN--------QCSGEGQGSRG 531
Q G G +G + G ++G G SS+SS G Q + +G GS G
Sbjct: 20 QPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTG 79
Query: 532 GQGS--NGQGSGGNQCSRDGQG-------TAGGHGSG--------------------GGQ 562
G GS + Q S G Q S G G T+G +GS GGQ
Sbjct: 80 GYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQ 139
Query: 563 R----------PGGGHG--------SGGGQGPGDGHGSG---GGKNSGGGKGSG------ 595
+ P G+G SGGG G G G G +SGGG G G
Sbjct: 140 QQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQ 199
Query: 596 -SGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFR 654
G GS G G++ + + R G P GG GG+G GG R
Sbjct: 200 SGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDR 259
Score = 53.5 bits (127), Expect = 1e-06
Identities = 45/142 (31%), Positives = 53/142 (37%), Gaps = 26/142 (18%)
Query: 475 QGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQG---SNGQGSSSHSSGG------------ 519
+G + G G PM G G G GGG+G S G G G
Sbjct: 377 RGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENM 436
Query: 520 --------NQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS- 570
NQC GG G G GGN D +G GG+ GG + GG G
Sbjct: 437 NFSWRNECNQCKAPKPDGPGG-GPGGSHMGGNY-GDDRRGGRGGYDRGGYRGRGGDRGGF 494
Query: 571 GGGQGPGDGHGSGGGKNSGGGK 592
GG+G GD G G GK G+
Sbjct: 495 RGGRGGGDRGGFGPGKMDSRGE 516
Score = 50.4 bits (119), Expect = 1e-05
Identities = 37/101 (36%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 554 GGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKR 613
GG+G GG R GG G GG G G G G GG SGGG G G + GD + +
Sbjct: 379 GGNGRGGRGR-GGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRA--GDWKCPNPTCEN 435
Query: 614 SYFGKLTQSKQQQMPPPPPPPPPPPPA--GGTGGKGKSGGR 652
F + Q + P P P P + GG G + GGR
Sbjct: 436 MNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGR 476
Score = 48.1 bits (113), Expect = 5e-05
Identities = 41/122 (33%), Positives = 47/122 (38%), Gaps = 39/122 (31%)
Query: 531 GGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQR---PGGGHGSGGGQGPGD--------- 578
GG G G+G GG G+G GG GSGGG R P GG G GG Q GD
Sbjct: 379 GGNGRGGRGRGGPM----GRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCE 434
Query: 579 -------------------GHGSG-GGKNSGGGKGS---GSGKGSDGDGERGKSLKKRSY 615
G G G GG + GG G G G D G RG+ + +
Sbjct: 435 NMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGF 494
Query: 616 FG 617
G
Sbjct: 495 RG 496
Score = 37.0 bits (84), Expect = 0.12
Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 11/93 (11%)
Query: 565 GGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQ 624
GGG+G GG +G G G GG GGG G G+G G G ++R+ K
Sbjct: 378 GGGNGRGG-RGRGGPMGRGG---YGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTC 433
Query: 625 QQMP-------PPPPPPPPPPPAGGTGGKGKSG 650
+ M P P P GG GG G
Sbjct: 434 ENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGG 466
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 85.1 bits (209), Expect = 4e-16
Identities = 62/163 (38%), Positives = 71/163 (43%), Gaps = 21/163 (12%)
Query: 462 GSGSGNF-GEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
G GSGNF G GN G G GG++ +G G G G G +G + GGN
Sbjct: 217 GGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGN 276
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQ------ 574
G G SRGG G G G G G G G+ GG GGG+ GGG
Sbjct: 277 YGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNF--GGGNYGGGGNYNDFGN 334
Query: 575 ---------GPGDGHGSGGGKNSGG--GKGSGSGKGSDGDGER 606
GP G GS GG++SG G G GSG GS G G R
Sbjct: 335 YSGQQQSNYGPMKG-GSFGGRSSGSPYGGGYGSGGGSGGYGSR 376
Score = 77.0 bits (188), Expect = 1e-13
Identities = 68/190 (35%), Positives = 80/190 (42%), Gaps = 38/190 (20%)
Query: 475 QGKEDQEGSGGDYMPMNNWGSGN--GRGS--GGGQGSNGQGSSSHSSGGNQCSGEGQGSR 530
Q Q G GG GSGN GRG GGG G+ G+G + GG G G GSR
Sbjct: 208 QSAGSQRGRGG--------GSGNFMGRGGNFGGGGGNFGRGGNFGGRGGY--GGGGGGSR 257
Query: 531 GGQGS-----NG-QGSGGNQCSRDGQGTAGGHGSGGG--QRPGGGHGSGGG-QGPGDGHG 581
G G NG G GGN G + GG+G GG GGG+G GGG G +G
Sbjct: 258 GSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGN 317
Query: 582 SGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAG 641
GGG GGG + G S +K S+ G+ + S P G
Sbjct: 318 FGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGS---------------PYGG 362
Query: 642 GTGGKGKSGG 651
G G G SGG
Sbjct: 363 GYGSGGGSGG 372
Score = 53.9 bits (128), Expect = 9e-07
Identities = 45/111 (40%), Positives = 53/111 (47%), Gaps = 12/111 (10%)
Query: 506 GSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQ--R 563
G N + + S Q +G +G GG G N G GGN G G G G+ GG+
Sbjct: 193 GHNCEVKKALSKQEMQSAGSQRGRGGGSG-NFMGRGGN--FGGGGGNFGRGGNFGGRGGY 249
Query: 564 PGGGHGSGGGQGPGDG--HGSGG-GKNSGGGKG----SGSGKGSDGDGERG 607
GGG GS G G GDG +G GG G N GGG G G G G G G +G
Sbjct: 250 GGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQG 300
Score = 48.5 bits (114), Expect = 4e-05
Identities = 36/100 (36%), Positives = 43/100 (43%), Gaps = 16/100 (16%)
Query: 515 HSSGGNQC------SGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGH 568
H+ G+ C S + S G Q G GSG + G G G GGG GG+
Sbjct: 189 HTINGHNCEVKKALSKQEMQSAGSQRGRGGGSG------NFMGRGGNFGGGGGNFGRGGN 242
Query: 569 GSGGGQGPGDGHGSGGGKNS-GGGKGSGSGKGSDGDGERG 607
G G G G G GG + S GGG G +G G DG G
Sbjct: 243 FGGRG---GYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGG 279
Score = 35.4 bits (80), Expect = 0.35
Identities = 26/85 (30%), Positives = 32/85 (37%), Gaps = 2/85 (2%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR--GSGGGQGSNGQGSSSHSSGG 519
G G GN G G D GG++ N G GN G+ GQ + G S G
Sbjct: 293 GPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFG 352
Query: 520 NQCSGEGQGSRGGQGSNGQGSGGNQ 544
+ SG G G G G G +
Sbjct: 353 GRSSGSPYGGGYGSGGGSGGYGSRR 377
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 81.3 bits (199), Expect = 5e-15
Identities = 50/122 (40%), Positives = 57/122 (46%), Gaps = 15/122 (12%)
Query: 474 PQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQ 533
P ++ QEG GG WG G G GGG+G G G GG G G G GG
Sbjct: 323 PPWQKRQEGGGG----RGGWGGGGG---GGGRGGGGGGGGRGGWGGG---GGGWGGGGGG 372
Query: 534 GSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKG 593
G G GG G+G G G GG+ GG G GG+G GD +G GGG GGG G
Sbjct: 373 GGGWGGGGGG-----GRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGG 427
Query: 594 SG 595
G
Sbjct: 428 GG 429
Score = 70.9 bits (172), Expect = 7e-12
Identities = 52/132 (39%), Positives = 55/132 (41%), Gaps = 28/132 (21%)
Query: 525 EGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGG 584
EG G RGG G G G G R G G GG G GG GG G GGG G G G G GG
Sbjct: 330 EGGGGRGGWGGGGGGGG-----RGGGGGGGGRGGWGG----GGGGWGGGGGGGGGWGGGG 380
Query: 585 GKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTG 644
G GG +G G G G G RG Y G+ P GG G
Sbjct: 381 GGGRGGFQGRGDYGGRGGYGGRG------GYGGR-------------GYGDPYGGGGGGG 421
Query: 645 GKGKSGGRFRLY 656
G G GG +R Y
Sbjct: 422 GGGGGGGGYRRY 433
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/164 (31%), Positives = 64/164 (39%), Gaps = 31/164 (18%)
Query: 421 RSRRAVSVPASFFRRLAPSPARPRH----PAEAPNNGARLSSEVSGSGSGNFGEEGNPQG 476
R + A ++ R+ RP P E P R + G G G +G G G
Sbjct: 290 REKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKR---QEGGGGRGGWGGGGGGGG 346
Query: 477 KEDQEGSGGDYMPMNNWGSGNGR---GSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQ 533
+ G GG WG G G G GGG G G G GG + +G+G GG+
Sbjct: 347 RGGGGGGGG----RGGWGGGGGGWGGGGGGGGGWGGGG------GGGRGGFQGRGDYGGR 396
Query: 534 GSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPG 577
G G G+G GG G G GGG G GGG G G
Sbjct: 397 GGYG-----------GRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 80.9 bits (198), Expect = 7e-15
Identities = 128/470 (27%), Positives = 160/470 (34%), Gaps = 68/470 (14%)
Query: 438 PSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNP--QGKEDQEGSGGDYMPMNNWGS 495
P PA PA P + ++ + G G G P +G +G GG P N G
Sbjct: 376 PGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGE 435
Query: 496 GNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAG 554
GS G G+ G+ G +GE +G RG +G G G G R G G+ G
Sbjct: 436 PGAPGSKGDTGAKGEPGPVGVQGPPGPAGE-EGKRGARGEPGPTGLPGPPGERGGPGSRG 494
Query: 555 GHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD----GERGKSL 610
G+ G P G G G GP GS G G G KG G G GK+
Sbjct: 495 FPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT- 553
Query: 611 KKRSYFGKLTQSKQQQMPPPPPPPPP---------PPPAGGTGGKGKSGGRFRLYFCVDR 661
G + Q P PP PP P P G G GK+G R
Sbjct: 554 ------GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER---GVPGPP 604
Query: 662 GATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMA 721
GA + E A+ P G A GP R P PG A P +
Sbjct: 605 GAVGPAGKDGEA-GAQGPPGPA-GPAGERGEQGPAGSPGFQGLPGPAGP---PGEAGKPG 659
Query: 722 PQNVSASKKRHSRSPFEDSRGYMMMFP---RVSPPPAPSPPKAPDTNKEDDSKDNDSESD 778
Q V S RG FP V PP P+ P+ + +D D+ +
Sbjct: 660 EQGVPGDLGAPGPSGARGERG----FPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715
Query: 779 YMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPM----LPG 834
APG+ P P ++ LP P + D + P PG
Sbjct: 716 ---GAPGSQGAPGLQGMPGERGAA-------GLPGP-------KGDRGDAGPKGADGSPG 758
Query: 835 KFLGRGLDKEVSYNWD---PKD-AASKPSG----EGSFSKPGDGGSPSKP 876
K RGL + P D S PSG G+ PGD G P P
Sbjct: 759 KDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPP 808
Score = 74.3 bits (181), Expect = 7e-13
Identities = 84/312 (26%), Positives = 107/312 (34%), Gaps = 25/312 (8%)
Query: 465 SGNFGEEG--NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQC 522
SGN G G P GKE +G G+ P G G G G G + +G
Sbjct: 889 SGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGA--- 945
Query: 523 SGEGQGSRGGQGSNGQ----GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGD 578
G+ G QG GQ G G + R G G G G Q P G G G GP
Sbjct: 946 ----PGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMG 1001
Query: 579 GHGSGGGKNSGGGKGSGSGKGSDG-DGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPP 637
G G G +G+ +GS G DG G + G+ + P P P P
Sbjct: 1002 PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR----GETGPAGPPGAPGAPGAPGPV 1057
Query: 638 PPAGGTGGKGKSGGRFRLYFCVDRGATKEC-KEAKEVKDAEIPEGAARGPHRARAFDEDE 696
PAG +G +G++G GA + E E RG R F +
Sbjct: 1058 GPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQ 1117
Query: 697 DDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPF------EDSRGYMMMFPRV 750
P P PG P +S P P + + + + RG V
Sbjct: 1118 GPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPV 1177
Query: 751 SPPPAPSPPKAP 762
PP P PP P
Sbjct: 1178 GPPGPPGPPGPP 1189
Score = 73.9 bits (180), Expect = 9e-13
Identities = 85/321 (26%), Positives = 118/321 (36%), Gaps = 44/321 (13%)
Query: 401 TPSEPVAHSRRGRLHLP--RGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSS 458
TP +RG + LP RG R + P+ + PS A P L+
Sbjct: 948 TPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAG 1007
Query: 459 EVSGSG-SGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSS 517
SG G G EG+P G++ G+ GD G G+ G G G S
Sbjct: 1008 PPGESGREGAPGAEGSP-GRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066
Query: 518 GGNQCSGEGQ-----GSRGGQGSNG-QGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG 571
G +G G+RG G G +G G + +G G G G Q P G GS
Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126
Query: 572 GGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG-------DGERGKSLKKRSYFGKLTQSKQ 624
G QGP G G + G G+ G +G G RG++ G +
Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRT----GDAGPVGPPG- 1181
Query: 625 QQMPPPPPPPPPPPPAG--------GTGGKGKSGGRFRLYFCVDRGATKE---------C 667
PP PP PP PP AG K GGR+ Y D ++
Sbjct: 1182 ---PPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRY--YRADDANVVRDRDLEVDTTLK 1236
Query: 668 KEAKEVKDAEIPEGAARGPHR 688
++++++ PEG+ + P R
Sbjct: 1237 SLSQQIENIRSPEGSRKNPAR 1257
Score = 65.5 bits (158), Expect = 3e-10
Identities = 72/254 (28%), Positives = 99/254 (38%), Gaps = 34/254 (13%)
Query: 417 PRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAP-NNGARLSSEVSGSGSGNFGEEGNP- 474
P G R R P + P PA PR AP N+GA+ + G+ G +G P
Sbjct: 672 PSGARGERGF--PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP----GSQGAPG 725
Query: 475 -QGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQ 533
QG + G+ G P + G +G+ G G +G + G +G G +G
Sbjct: 726 LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG-APGDKGES 784
Query: 534 GSNG-------QGSGGNQCSRDGQGTAGGHGSGGGQ-RPG-----GGHGSGGGQGPGDGH 580
G +G +G+ G++ G AG G G +PG G G+ G GP
Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844
Query: 581 GSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPP----PPPP 636
G G G G+ KG+ G + G++ PP P PP P
Sbjct: 845 GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG-------PPGPSGNAGPPGP 897
Query: 637 PPPAGGTGGKGKSG 650
P PAG GGKG G
Sbjct: 898 PGPAGKEGGKGPRG 911
Score = 64.3 bits (155), Expect = 7e-10
Identities = 127/509 (24%), Positives = 162/509 (31%), Gaps = 86/509 (16%)
Query: 402 PSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPA-----------EAP 450
P P A + G + P + A P R P P PA P
Sbjct: 568 PGPPGARGQAGVMGFPG---PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624
Query: 451 NNGARLSSEVSGSGSGNF----GEEGNP--QGKEDQEGSGGDYMPMNNWGSGNGRGSGGG 504
A E +GS F G G P GK ++G GD G+ RG G
Sbjct: 625 AGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGE 684
Query: 505 QGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRP 564
+G G + G N G G++G G+ G+ G+Q + QG G G+ G P
Sbjct: 685 RGVQGPPGPAGPRGANGAPGN-DGAKGDAGA--PGAPGSQGAPGLQGMPGERGAAGLPGP 741
Query: 565 GGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKKRSYFGKLTQSK 623
G G G +G G G + G G G+ GD GE G S G +
Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPS-------GPAGPTG 794
Query: 624 QQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAA 683
+ P P PP PAG G G G GA E +A DA
Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADG---------QPGAKGEPGDAGAKGDA------- 838
Query: 684 RGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGY 743
GP PG A P + P+ +K + + G+
Sbjct: 839 -GP------------------PGPAGP---AGPPGPIGNVGAPGAKGARGSAGPPGATGF 876
Query: 744 MMMFPRVSPPPAPS----PPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGG 799
RV PP PS PP P ++ K E+ G P P P G
Sbjct: 877 PGAAGRVG-PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG--PPGPPGPAGE 933
Query: 800 SSSKSWSSYFSLP-NPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDP-KDAASK 857
S P P GQ V LPG+ RG + +P K S
Sbjct: 934 KGSPGADGPAGAPGTPGPQGIAGQRG----VVGLPGQRGERGFPGLPGPSGEPGKQGPSG 989
Query: 858 PSGE----GSFSKPGDGGSPSKPSDHEPP 882
SGE G PG G P + P
Sbjct: 990 ASGERGPPGPMGPPGLAGPPGESGREGAP 1018
Score = 60.8 bits (146), Expect = 8e-09
Identities = 62/216 (28%), Positives = 76/216 (35%), Gaps = 39/216 (18%)
Query: 466 GNFGEEG-----NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
G+ GE G P+G + G G P G+ G+ G G G G
Sbjct: 290 GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349
Query: 521 QCSGEG--QGSRGGQGSNG-------------QGSGGNQCSRDGQ----------GTAGG 555
GE QG RG +G G G GN DGQ G AG
Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP-GADGQPGAKGANGAPGIAGA 408
Query: 556 HGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKKRS 614
G G + P G G GG GP G+ G + G KG KG G G +G
Sbjct: 409 PGFPGARGPSGPQGPGGPPGP---KGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP----G 461
Query: 615 YFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
G+ + + P P P PP GG G +G G
Sbjct: 462 PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG 497
Score = 59.3 bits (142), Expect = 2e-08
Identities = 60/215 (27%), Positives = 78/215 (36%), Gaps = 24/215 (11%)
Query: 440 PARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR 499
P P P + G R G +G+ GE G P G+ + G G G+
Sbjct: 205 PGEPGEPGASGPMGPRGPPGPPGK-NGDDGEAGKP-GRPGERGPPGPQGARGLPGTAGLP 262
Query: 500 GSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGGHGS 558
G G +G +G + +G GE GS G G+ GQ G G R G G G+
Sbjct: 263 GMKGHRGFSGLDGAKGDAGPAGPKGE-PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA 321
Query: 559 GGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG-DGERGKSLKKRSYFG 617
G G G G GP G G + G G +GS+G G RG+
Sbjct: 322 RGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGE--------- 372
Query: 618 KLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGR 652
P PP P PAG G G+ G +
Sbjct: 373 ----------PGPPGPAGAAGPAGNPGADGQPGAK 397
Score = 58.9 bits (141), Expect = 3e-08
Identities = 124/543 (22%), Positives = 165/543 (30%), Gaps = 81/543 (14%)
Query: 442 RPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGS 501
+P P E G + + + G+ +G G +G+ +G +G+ GD P G G
Sbjct: 237 KPGRPGERGPPGPQGARGLPGT-AGLPGMKGH-RGFSGLDGAKGDAGPAGPKGEPGSPGE 294
Query: 502 GGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQ----GTAGGHG 557
G G G G G G+RG G+ G G G G G
Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPA-GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKG 353
Query: 558 SGGGQRPGGGHGSG---GGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG-DGERGKSLKKR 613
G Q P G G G GP G+ G + G G KG++G G G
Sbjct: 354 EAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAP---- 409
Query: 614 SYFGKLTQSKQQQMPPPPPP------PPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKEC 667
+ G S Q PP P P P G TG KG+ G V
Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGP-----VGVQGPPGPAG 464
Query: 668 KEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSA 727
+E K E GP R P G P P P+
Sbjct: 465 EEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG 524
Query: 728 SKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAG 787
R + ++G P +P P D K PG
Sbjct: 525 EAGRPGEAGLPGAKGL------TGSPGSPGP----------DGKTG---------PPGPA 559
Query: 788 AIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSY 847
P P G ++ + P P ++ VP PG G D E
Sbjct: 560 GQDGRP-GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA 618
Query: 848 NWDPKDAASKPSGE----------------GSFSKPGDGGSPSK---PSDHEPPKNKAKR 888
P A P+GE G PG+ G P + P D P R
Sbjct: 619 QGPPGPAG--PAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676
Query: 889 PNRLSFITKGYKIKPKPQKPTHEQREADSSSDYVNMDFTKRESNTP-APSTQGLPDSWGI 947
R +G + P P P R A+ + D K ++ P AP +QG P G+
Sbjct: 677 GERGFPGERGVQGPPGPAGP----RGANGAP---GNDGAKGDAGAPGAPGSQGAPGLQGM 729
Query: 948 IAE 950
E
Sbjct: 730 PGE 732
Score = 45.4 bits (106), Expect = 3e-04
Identities = 107/448 (23%), Positives = 137/448 (30%), Gaps = 62/448 (13%)
Query: 447 AEAPNNGARLSSEVSGSGSGNFGEEG--NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGG 504
+E+P + E +G G G P G++ G G P G G GG
Sbjct: 99 SESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGN 158
Query: 505 QGSN-GQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGGHGSGGGQ 562
G S+GG G G G +G G G+ G Q QG G G G
Sbjct: 159 FAPQLSYGYDEKSTGGISVPGP-MGPSGPRGLPGPPGAPGPQ---GFQGPPGEPGEPGAS 214
Query: 563 RPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG-DGERG-KSLKKRSYFGKLT 620
P G G G G G G G +G +G+ G G G +K F L
Sbjct: 215 GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274
Query: 621 QSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPE 680
+K P P P P G G G+ G R E
Sbjct: 275 GAKGDAGPAGPKGEPGSP--GENGAPGQMGPRGL--------------------PGERGR 312
Query: 681 GAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDS 740
A GP AR D P G A P P P V A + + P S
Sbjct: 313 PGAPGPAGARGNDGATGAAGPPGPTGPAGP--------PGFPGAVGAKGEAGPQGP-RGS 363
Query: 741 RGYMMMFPRVSP-PPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIP--KNPRNPQ 797
G + R P PP P+ P N D + ++ GA P + P PQ
Sbjct: 364 EGPQGV--RGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQ 421
Query: 798 GGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASK 857
G P G N P G +G V P A +
Sbjct: 422 GPGGPPG--------------PKG-NSGEPGAPGSKGDTGAKGEPGPVGVQ-GPPGPAGE 465
Query: 858 PSGEGSFSKPGDGGSPSKPSDHEPPKNK 885
G+ +PG G P P + P ++
Sbjct: 466 EGKRGARGEPGPTGLPGPPGERGGPGSR 493
Score = 33.5 bits (75), Expect = 1.3
Identities = 31/120 (25%), Positives = 40/120 (33%), Gaps = 5/120 (4%)
Query: 531 GGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGG 590
G + Q + G + + G G G G G G G GP G G GG
Sbjct: 98 GSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGG 157
Query: 591 GKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
G D G S+ G + S + +P PP P P G G G+ G
Sbjct: 158 NFAPQLSYGYDEKSTGGISVP-----GPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPG 212
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 78.6 bits (192), Expect = 4e-14
Identities = 57/187 (30%), Positives = 69/187 (36%), Gaps = 22/187 (11%)
Query: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
G NFG N QG Q G G N G N SG G GS+ G S S G+ S
Sbjct: 200 GPPNFGT--NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
Query: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG 583
G + G S G SG + G + G G+ GG R G S G G G+
Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
Query: 584 GGKNSGGGKGSG---SGKGSDGDGERG-----------------KSLKKRSYFGKLTQSK 623
GG G G G G + G GE G K+ K + F
Sbjct: 318 GGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKSKLGFINWDAIN 377
Query: 624 QQQMPPP 630
+ Q+PPP
Sbjct: 378 KNQVPPP 384
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/172 (31%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGS---- 512
+ G G GN G G P S G + MN G+ G+G GG G+N QG+
Sbjct: 157 LGGQGQGNPGGLGTPWVHGYPGNSAGSF-GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
Query: 513 ---SSHSSGGNQ-CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG---GGQRPG 565
S +S N+ C+ GG SN G G+Q G G+ G + +G GG G
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
Query: 566 GGHG--SGGGQGPGDGHGSG----GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
G SGG G G+ G G S G +GS G+ G G K
Sbjct: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
Score = 63.9 bits (154), Expect = 9e-10
Identities = 56/200 (28%), Positives = 84/200 (42%), Gaps = 21/200 (10%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
+G +G+ E QG + G+G +P +G+ + G+ G+ ++ G++ H G
Sbjct: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQ 116
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG--GGQG--- 575
G+ +GS QG G+ + + T+GGHG G Q GG G G GG G
Sbjct: 117 AEDVIRHGADAVRGS-WQGVPGHNGAWE---TSGGHGIFGSQGGLGGQGQGNPGGLGTPW 172
Query: 576 ----PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPP 631
PG+ GS G G G G G G + + +G + S Q +
Sbjct: 173 VHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE----- 227
Query: 632 PPPPPPPPAGGTGGKGKSGG 651
PPP+G GG SGG
Sbjct: 228 -GCTNPPPSGSGGGSSNSGG 246
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 78.2 bits (191), Expect = 5e-14
Identities = 147/561 (26%), Positives = 175/561 (31%), Gaps = 103/561 (18%)
Query: 435 RLAPSPARPRHPAEAPNN-------GAR-LSSEVSGSGS-------GNFGEEGNP----- 474
R AP PA PR A P G R + G GS G+ GE G P
Sbjct: 509 RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568
Query: 475 QGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQG 534
G Q G G P N G+ G GG G G +G G +G G
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET-------GPQGPPG 621
Query: 535 SNGQGSGGNQCSRDG-QGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKG 593
G G G QG G G+GG G G G +G G+ GGK G G
Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPG 681
Query: 594 SGSGKGSDG-DGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGR 652
G G G RG + GK PP PP AG G +G G R
Sbjct: 682 ERGPPGLAGAPGLRGGAGPPGPEGGKGAAG----------PPGPPGAAGTPGLQGMPGER 731
Query: 653 FRLYFCVDRGATKE--CKEAKEVKDAEIPEGAAR--GPHRARAFDEDEDDPYVPMRPGVA 708
L +G E A V + P G GP D+ + P PG+A
Sbjct: 732 GGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791
Query: 709 TPLVSSSDY----------MPMAP-QNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPS 757
P S + P AP QN K +P E G P V+ PP S
Sbjct: 792 GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGP---PGVAGPPGGS 848
Query: 758 PPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRS 817
P P PG + K R GG + + LP
Sbjct: 849 GPAGP---------------------PGPQGV-KGERGSPGGPGAAGFPGARGLP----- 881
Query: 818 SPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSK-- 875
P G N N P PG G D P P G GD G P +
Sbjct: 882 GPPGSNGN----PGPPGPSGSPGKDGPPG----PAGNTGAPGSPGVSGPKGDAGQPGEKG 933
Query: 876 -PSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKP----THEQREADSSSDYVNMDFTKRE 930
P PP A P ++ IT + P P + + S + E
Sbjct: 934 SPGAQGPP--GAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE 991
Query: 931 SNTPAPSTQGLPDSWGIIAEP 951
P P QGLP G EP
Sbjct: 992 RGPPGP--QGLPGLAGTAGEP 1010
Score = 65.9 bits (159), Expect = 2e-10
Identities = 120/474 (25%), Positives = 149/474 (31%), Gaps = 103/474 (21%)
Query: 472 GNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRG 531
G P G+ + G G G+ G+G G G G + + G RG
Sbjct: 647 GGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA----------PGLRG 696
Query: 532 GQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGG 591
G G G GG G+ G P G G+ G QG G G G
Sbjct: 697 GAGP--------------PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742
Query: 592 KGSGSGKGSDG----DGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKG 647
KG G G+DG DG RG P P PP PAG G KG
Sbjct: 743 KGEPGGPGADGVPGKDGPRG----------------------PTGPIGPPGPAGQPGDKG 780
Query: 648 KSGGRFRLYFCVDRGATKECKEAKEVKDAEIP-------EGAARGPHRARAFDEDEDDPY 700
+ G RG+ E E A P E +G R ++ E P
Sbjct: 781 EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG-ERGAPGEKGEGGP- 838
Query: 701 VPMRPGVATPLVSSSDYMPMAPQNVS---ASKKRHSRSPFEDSRGYM----------MMF 747
PGVA P S P PQ V S + F +RG
Sbjct: 839 ----PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894
Query: 748 PRVSP----PPAPS----PPKAPDTN--KEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQ 797
P SP PP P+ P +P + K D + + S PGA P
Sbjct: 895 PSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA----PGPLGIA 950
Query: 798 GGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASK 857
G + ++ + +P P R SP Q E GK GL E P
Sbjct: 951 GITGARGLAGPPGMPGP-RGSPGPQGVKGE-----SGKPGANGLSGERG----PPGPQGL 1000
Query: 858 PSGEGSFSKPGDGGSPSK---PSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKP 908
P G+ +PG G+P P P K R S G P P P
Sbjct: 1001 PGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP 1054
Score = 64.3 bits (155), Expect = 7e-10
Identities = 76/237 (32%), Positives = 91/237 (38%), Gaps = 44/237 (18%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSG--SGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSG 496
SP + P A N GA S VSG +G GE+G+P G + G+ G P+ G
Sbjct: 898 SPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSP-GAQGPPGAPG---PLGIAGIT 953
Query: 497 NGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGG 555
RG G G G S G GE G G G +G+ G G Q GTAG
Sbjct: 954 GARGLAGPPGMPGPRGSPGPQG---VKGES-GKPGANGLSGERGPPGPQGLPGLAGTAGE 1009
Query: 556 HGSGGGQRPG-----GGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG-DGERGKS 609
G G PG G GS GG+G +GS G + G G G G G+RG+S
Sbjct: 1010 PGRDG--NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067
Query: 610 LKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKE 666
P P P PAG G G G R D+G T E
Sbjct: 1068 -------------------GPAGPAGAPGPAGSRGAPGPQGPR------GDKGETGE 1099
Score = 63.2 bits (152), Expect = 2e-09
Identities = 64/218 (29%), Positives = 79/218 (36%), Gaps = 34/218 (15%)
Query: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGG 519
++GS G GE G P G G G P G+ G GG G G+ + G
Sbjct: 388 INGSPGGK-GEMG-PAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGP 445
Query: 520 NQCSGEG--------------QGSRGGQGSNG-QGSGGNQCSRDGQGTAGGHGSGGGQRP 564
GE GS G G+NG G+ G + + +G AG +G G + P
Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP 505
Query: 565 GGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGS-DGDGERGKSLKKRSYFGKLTQSK 623
G G+ G GP G G GG G GS G G GK G
Sbjct: 506 AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP-------GPPGSQG 558
Query: 624 QQQMPPPPPPPPP---------PPPAGGTGGKGKSGGR 652
+ P PP P P P P G G GK+G R
Sbjct: 559 ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGER 596
Score = 60.5 bits (145), Expect = 1e-08
Identities = 115/433 (26%), Positives = 143/433 (33%), Gaps = 82/433 (18%)
Query: 469 GEEGNP--------QGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
GE G P +G + GS G P G+ GS G +G G S S+G
Sbjct: 306 GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAP 365
Query: 521 QCSGE--GQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGD 578
GE QG G QG G G S G+G G G G G G+ G GP
Sbjct: 366 GQRGEPGPQGHAGAQGP--PGPPGINGSPGGKGEMGPAGIPGAP---GLMGARGPPGPAG 420
Query: 579 GHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPP 637
+G+ G + G G KG G GERG++ G + + P P P
Sbjct: 421 ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA-GIPGVPGAKGEDGKDGSPGEPGANGLP 479
Query: 638 PPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDED 697
AG G G G ++G E + P GAA P R D
Sbjct: 480 GAAGERGAPGFRGPAGPNGIPGEKGPAGE----RGAPGPAGPRGAAGEPGR----DGVPG 531
Query: 698 DPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPS 757
P + PG +P SD P P + S + PP PS
Sbjct: 532 GPGMRGMPG--SPGGPGSDGKPGPPGSQGESGR--------------------PGPPGPS 569
Query: 758 PPKA-PDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFR 816
P+ P K ND APG R GG P P
Sbjct: 570 GPRGQPGVMGFPGPKGNDG-------APG----KNGERGGPGG------------PGP-- 604
Query: 817 SSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKP 876
P G+ N E P P G G DK + P+ P G+ PG+ G P +P
Sbjct: 605 QGPPGK--NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLP---GTGGPPGENGKPGEP 659
Query: 877 SDHEPPKNKAKRP 889
PK A P
Sbjct: 660 G----PKGDAGAP 668
Score = 57.0 bits (136), Expect = 1e-07
Identities = 61/233 (26%), Positives = 76/233 (32%), Gaps = 49/233 (21%)
Query: 440 PARPRHPAEAPNNGARLSSEVSGSGSGNFGEEG--NPQGKEDQEGSGGDYMPMNNWGSGN 497
P R P + G S G+ G+ G G P GK G G P G
Sbjct: 1022 PGRDGSPGGKGDRGENGSPGAPGA-PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080
Query: 498 GRGSGGGQ------GSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQ 550
RG+ G Q G G+ ++ G +G G G+ G G G Q +
Sbjct: 1081 SRGAPGPQGPRGDKGETGERGAAGIKG-------HRGFPGNPGAPGSPGPAGQQGAIGSP 1133
Query: 551 GTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSL 610
G AG G G P G G+ G GP G G + G +GS G G
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG-------- 1185
Query: 611 KKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGK------GKSGGRFRLYF 657
PP PP P P GG G G+ G F Y+
Sbjct: 1186 ------------------PPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYY 1220
Score = 54.7 bits (130), Expect = 6e-07
Identities = 59/217 (27%), Positives = 71/217 (32%), Gaps = 42/217 (19%)
Query: 438 PSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGN--PQGKEDQEGSGGDYMPMNNWGS 495
P PA P P P S S G GE G P G G+ G P G
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGE 232
Query: 496 GNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAG 554
G G +G G +G G +G RG G NG+ G G + G G
Sbjct: 233 SGRPGRPGERGLPGPPGIKGPAGIPGFPGM-KGHRGFDGRNGEKGETGAPGLKGENGLPG 291
Query: 555 GHGSGGGQRPGGGHGSGGGQG-PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKR 613
+G+ G P G G G G PG + G +G+ +GSDG
Sbjct: 292 ENGAPGPMGPRGAPGERGRPGLPG----------AAGARGNDGARGSDGQ---------- 331
Query: 614 SYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
P PP PP AG G G G
Sbjct: 332 -----------------PGPPGPPGTAGFPGSPGAKG 351
Score = 41.6 bits (96), Expect = 0.005
Identities = 50/193 (25%), Positives = 62/193 (32%), Gaps = 9/193 (4%)
Query: 412 GRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEE 471
GR P G+ R P + P P P PA + G G
Sbjct: 1023 GRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSR 1082
Query: 472 G--NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEG--- 526
G PQG +G G+ G G+ G GS G + G +G
Sbjct: 1083 GAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPV 1142
Query: 527 --QGSRGGQGSNGQ-GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGP-GDGHGS 582
G G G++G G G R +G G GS G G G G GP G G+
Sbjct: 1143 GPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGA 1202
Query: 583 GGGKNSGGGKGSG 595
GG K G
Sbjct: 1203 AAIAGIGGEKAGG 1215
Score = 38.9 bits (89), Expect = 0.031
Identities = 88/389 (22%), Positives = 123/389 (31%), Gaps = 55/389 (14%)
Query: 497 NGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGH 556
NG+G G +G G +G G+ G GS G C Q + +
Sbjct: 100 NGQGPQGPKGDPGPPGIPGRNGDPGIPGQP----GSPGSPGPPGICESCPTGPQNYSPQY 155
Query: 557 GS---GGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKK 612
S G GG G G GP G G G GS +G G+ G+ G S
Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPS--- 212
Query: 613 RSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKE 672
PP PP P+G G G+SG R +
Sbjct: 213 ----------------GPPGPPGAIGPSGPAGKDGESGR-------PGRPGERGLPGPPG 249
Query: 673 VK-DAEIPEGAARGPHRARAFDEDEDDPYVPMRPGV----ATPLVSSSDYMPMAPQNVSA 727
+K A IP H R FD + PG+ P + + PM P+
Sbjct: 250 IKGPAGIPGFPGMKGH--RGFDGRNGEKGETGAPGLKGENGLPGENGAP-GPMGPRGAPG 306
Query: 728 SKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAG 787
+ R +RG P P PP +K + +PG+
Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAG----SPGSN 362
Query: 788 AIP--KNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQND-NSEYVPMLPGKFLGRGLDKE 844
P + PQG + ++ P SP G+ + +P PG RG
Sbjct: 363 GAPGQRGEPGPQGHAGAQGPPG----PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGP 418
Query: 845 VSYNWDP--KDAASKPSGEGSFSKPGDGG 871
N P + A +P G+ +PG G
Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPRG 447
Score = 32.3 bits (72), Expect = 2.9
Identities = 29/99 (29%), Positives = 34/99 (34%), Gaps = 11/99 (11%)
Query: 563 RPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG---------DGERGKSLKKR 613
RP G G G +G G G G G GS G G + S +
Sbjct: 97 RPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYD 156
Query: 614 SYFGK--LTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
SY K + P P PP PP P G +G G G
Sbjct: 157 SYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG 195
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 77.8 bits (190), Expect = 6e-14
Identities = 56/136 (41%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 463 SGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQC 522
SG G G+ G G + G GGD G G RG GG G G GG++
Sbjct: 448 SGGGYGGDRGGGYGGDRGGGYGGD----RGGGYGGDRGGYGGDRGGGYGGDRGGYGGDR- 502
Query: 523 SGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG-GGQRPG--GGHGSGGGQGPGDG 579
G G RGG G + G GG++ SR G G G GSG GG R G GG SGGG G G
Sbjct: 503 -GGYGGDRGGYGGDRGGYGGDR-SRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRG 560
Query: 580 HGSGGGKNSGGGKGSG 595
G GG + GGK G
Sbjct: 561 GGYGGDRGGYGGKMGG 576
Score = 75.5 bits (184), Expect = 3e-13
Identities = 54/141 (38%), Positives = 59/141 (41%), Gaps = 6/141 (4%)
Query: 473 NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSS---GGNQCSGEG-QG 528
N ED SGGD+ G RG GG G G S GG++ SG G G
Sbjct: 377 NEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSG 436
Query: 529 SRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG-GGQRPGGGHGSGGGQGPGDGHGSGGGKN 587
R G G G SGG G G G G G GG R GG G GG G G G GG +
Sbjct: 437 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 496
Query: 588 SGGGKGSGSGKGSDG-DGERG 607
GG G G G G+RG
Sbjct: 497 GYGGDRGGYGGDRGGYGGDRG 517
Score = 75.1 bits (183), Expect = 4e-13
Identities = 61/167 (36%), Positives = 69/167 (41%), Gaps = 17/167 (10%)
Query: 451 NNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQ 510
++G S + SG G G G G + G GGD G G RG G G G
Sbjct: 429 SSGGGYSGDRSGGGYGG-DRSGGGYGGDRGGGYGGD----RGGGYGGDRGGGYGGDRGGY 483
Query: 511 GSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
G G G G G RGG G + G GG+ +G GG S GG GG G
Sbjct: 484 GGDRGGGYGGDRGGYG-GDRGGYGGDRGGYGGD------RGGYGGDRSRGGY--GGDRGG 534
Query: 571 GGGQGPGDGHGSGGGKNSGGGKGS--GSGKGSDGDGERGKSLKKRSY 615
G G G GD G GG SGGG G G G G D G GK + Y
Sbjct: 535 GSGYG-GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 580
Score = 73.2 bits (178), Expect = 1e-12
Identities = 66/209 (31%), Positives = 82/209 (39%), Gaps = 20/209 (9%)
Query: 431 SFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGE--EGNPQGKEDQEGSGGDYM 488
+F RR + + P ++ +G G G G G +G + SGG Y
Sbjct: 366 NFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYG 425
Query: 489 PMNNWGSG-NGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQ-------------G 534
+ G G +G SGGG G + G G G+ G GG G
Sbjct: 426 GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGG 485
Query: 535 SNGQGSGGNQCSRDGQ--GTAGGHGSGGGQRPG-GGHGSGGGQGPGDGHGSG-GGKNSGG 590
G G GG++ G G G G GG R G GG S GG G G GSG GG SGG
Sbjct: 486 DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGG 545
Query: 591 GKGSGSGKGSDGDGERGKSLKKRSYFGKL 619
G SG G GD G + Y GK+
Sbjct: 546 YGGDRSGGGYGGDRGGGYGGDRGGYGGKM 574
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/152 (35%), Positives = 63/152 (41%), Gaps = 34/152 (22%)
Query: 490 MNNWGSGNGR---GSGGGQGS-NGQGSSSHS------------------SGGNQCS-GEG 526
M GSG GR G G+G G+G S + NQC+
Sbjct: 322 MRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRP 381
Query: 527 QGSRGGQGS-NGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG---SGGGQGPGDGHGS 582
+ SR G G+G GG + R G G G GG R GGG+G S GG GD G
Sbjct: 382 EDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGG 441
Query: 583 G-GGKNSGGGKGSGSGKGSDGD------GERG 607
G GG SGGG G G G GD G+RG
Sbjct: 442 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG 473
Score = 47.4 bits (111), Expect = 9e-05
Identities = 42/173 (24%), Positives = 66/173 (38%), Gaps = 13/173 (7%)
Query: 451 NNGARLSSEVSGSGSG--------NFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSG 502
N G + + E SGS G ++G++ + + + G Y +N+ + S
Sbjct: 82 NQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQ 141
Query: 503 GGQGSNGQGSS-SHSSGGNQCS----GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHG 557
Q + Q + SH + ++ GE GG G+G GG G T G
Sbjct: 142 NQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGG 201
Query: 558 SGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSL 610
GG + GGH G + D N+ +G G G +D GE K +
Sbjct: 202 DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQI 254
Score = 39.7 bits (91), Expect = 0.018
Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 6/90 (6%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGS-SSHSSGGN 520
G G G+ G G D+ G GGD + G G RG G G G + G SGG
Sbjct: 500 GDRGGYGGDRGGYGG--DRGGYGGD---RSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 554
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQ 550
G G G +G G GG R+ Q
Sbjct: 555 YGGDRGGGYGGDRGGYGGKMGGRNDYRNDQ 584
Score = 38.1 bits (87), Expect = 0.053
Identities = 35/124 (28%), Positives = 48/124 (38%), Gaps = 9/124 (7%)
Query: 463 SGSGNFGEEGNPQGKEDQEGSGGD--YMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
S SG++G+ G Q G+ G Y + SG G+ + G N G SS+ +
Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYS 61
Query: 521 QCSG----EGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGP 576
Q G + Q S Q N Q G Q + + G+ GG Q G S Q
Sbjct: 62 QSYGGYENQKQSSYSQQPYNNQ---GQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSG 118
Query: 577 GDGH 580
D H
Sbjct: 119 YDQH 122
Score = 33.9 bits (76), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 579 GHGSGGGKNS-GGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPP--PPPPPP 635
G GSGGG+ GG +G G +G GD + G + G + +++ P P
Sbjct: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
Query: 636 PPPPAGGTGGKGKSGGR 652
P G G+G G R
Sbjct: 384 SRPSGGDFRGRGYGGER 400
Score = 31.2 bits (69), Expect = 6.5
Identities = 31/130 (23%), Positives = 48/130 (36%), Gaps = 8/130 (6%)
Query: 500 GSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQ---CSRDGQGTAGGH 556
GS G G Q S++ + G+Q G+ S G G S G S GQ + +
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQSY 64
Query: 557 GSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYF 616
G Q+ S Q P + G S G +G + D + S ++S +
Sbjct: 65 GGYENQKQ-----SSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGY 119
Query: 617 GKLTQSKQQQ 626
+ S +Q
Sbjct: 120 DQHQGSYDEQ 129
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 77.8 bits (190), Expect = 6e-14
Identities = 56/136 (41%), Positives = 64/136 (47%), Gaps = 10/136 (7%)
Query: 463 SGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQC 522
SG G G+ G G + G GGD G G RG GG G G GG++
Sbjct: 451 SGGGYGGDRGGGYGGDRGGGYGGD----RGGGYGGDRGGYGGDRGGGYGGDRGGYGGDR- 505
Query: 523 SGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG-GGQRPG--GGHGSGGGQGPGDG 579
G G RGG G + G GG++ SR G G G GSG GG R G GG SGGG G G
Sbjct: 506 -GGYGGDRGGYGGDRGGYGGDR-SRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRG 563
Query: 580 HGSGGGKNSGGGKGSG 595
G GG + GGK G
Sbjct: 564 GGYGGDRGGYGGKMGG 579
Score = 75.5 bits (184), Expect = 3e-13
Identities = 54/141 (38%), Positives = 59/141 (41%), Gaps = 6/141 (4%)
Query: 473 NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSS---GGNQCSGEG-QG 528
N ED SGGD+ G RG GG G G S GG++ SG G G
Sbjct: 380 NEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSG 439
Query: 529 SRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG-GGQRPGGGHGSGGGQGPGDGHGSGGGKN 587
R G G G SGG G G G G G GG R GG G GG G G G GG +
Sbjct: 440 DRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 499
Query: 588 SGGGKGSGSGKGSDG-DGERG 607
GG G G G G+RG
Sbjct: 500 GYGGDRGGYGGDRGGYGGDRG 520
Score = 75.1 bits (183), Expect = 4e-13
Identities = 61/167 (36%), Positives = 69/167 (41%), Gaps = 17/167 (10%)
Query: 451 NNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQ 510
++G S + SG G G G G + G GGD G G RG G G G
Sbjct: 432 SSGGGYSGDRSGGGYGG-DRSGGGYGGDRGGGYGGD----RGGGYGGDRGGGYGGDRGGY 486
Query: 511 GSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
G G G G G RGG G + G GG+ +G GG S GG GG G
Sbjct: 487 GGDRGGGYGGDRGGYG-GDRGGYGGDRGGYGGD------RGGYGGDRSRGGY--GGDRGG 537
Query: 571 GGGQGPGDGHGSGGGKNSGGGKGS--GSGKGSDGDGERGKSLKKRSY 615
G G G GD G GG SGGG G G G G D G GK + Y
Sbjct: 538 GSGYG-GDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDY 583
Score = 73.2 bits (178), Expect = 1e-12
Identities = 66/209 (31%), Positives = 82/209 (39%), Gaps = 20/209 (9%)
Query: 431 SFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGE--EGNPQGKEDQEGSGGDYM 488
+F RR + + P ++ +G G G G G +G + SGG Y
Sbjct: 369 NFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYG 428
Query: 489 PMNNWGSG-NGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQ-------------G 534
+ G G +G SGGG G + G G G+ G GG G
Sbjct: 429 GDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGG 488
Query: 535 SNGQGSGGNQCSRDGQ--GTAGGHGSGGGQRPG-GGHGSGGGQGPGDGHGSG-GGKNSGG 590
G G GG++ G G G G GG R G GG S GG G G GSG GG SGG
Sbjct: 489 DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGG 548
Query: 591 GKGSGSGKGSDGDGERGKSLKKRSYFGKL 619
G SG G GD G + Y GK+
Sbjct: 549 YGGDRSGGGYGGDRGGGYGGDRGGYGGKM 577
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/152 (35%), Positives = 63/152 (41%), Gaps = 34/152 (22%)
Query: 490 MNNWGSGNGR---GSGGGQGS-NGQGSSSHS------------------SGGNQCS-GEG 526
M GSG GR G G+G G+G S + NQC+
Sbjct: 325 MRGGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRP 384
Query: 527 QGSRGGQGS-NGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHG---SGGGQGPGDGHGS 582
+ SR G G+G GG + R G G G GG R GGG+G S GG GD G
Sbjct: 385 EDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGG 444
Query: 583 G-GGKNSGGGKGSGSGKGSDGD------GERG 607
G GG SGGG G G G GD G+RG
Sbjct: 445 GYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRG 476
Score = 47.4 bits (111), Expect = 9e-05
Identities = 42/173 (24%), Positives = 66/173 (38%), Gaps = 13/173 (7%)
Query: 451 NNGARLSSEVSGSGSG--------NFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSG 502
N G + + E SGS G ++G++ + + + G Y +N+ + S
Sbjct: 85 NQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQ 144
Query: 503 GGQGSNGQGSS-SHSSGGNQCS----GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHG 557
Q + Q + SH + ++ GE GG G+G GG G T G
Sbjct: 145 NQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGG 204
Query: 558 SGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSL 610
GG + GGH G + D N+ +G G G +D GE K +
Sbjct: 205 DRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFKQI 257
Score = 39.7 bits (91), Expect = 0.018
Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 6/90 (6%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGS-SSHSSGGN 520
G G G+ G G D+ G GGD + G G RG G G G + G SGG
Sbjct: 503 GDRGGYGGDRGGYGG--DRGGYGGD---RSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 557
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQ 550
G G G +G G GG R+ Q
Sbjct: 558 YGGDRGGGYGGDRGGYGGKMGGRNDYRNDQ 587
Score = 39.3 bits (90), Expect = 0.024
Identities = 39/129 (30%), Positives = 50/129 (38%), Gaps = 16/129 (12%)
Query: 463 SGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGSSSHSSGG 519
S SG++G+ G Q G+ G +G + SG GQ S GQ S +SS G
Sbjct: 2 SDSGSYGQSGGEQQSYSTYGNPGS----QGYGQASQSYSGYGQTTDSSYGQNYSGYSSYG 57
Query: 520 NQCSGEGQGSRGGQGSNGQGS--------GGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG 571
SG Q S GG + Q S G Q + + G+ GG Q G S
Sbjct: 58 QSQSGYSQ-SYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSY 116
Query: 572 GGQGPGDGH 580
Q D H
Sbjct: 117 DQQSGYDQH 125
Score = 35.8 bits (81), Expect = 0.26
Identities = 34/130 (26%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 500 GSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG 559
GS G G Q S++ + G+Q G+ S G G S G S G + G SG
Sbjct: 5 GSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYS--GYSSYGQSQSG 62
Query: 560 GGQRPGGGHG---SGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYF 616
Q GG S Q P + G S G +G + D + S ++S +
Sbjct: 63 YSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGY 122
Query: 617 GKLTQSKQQQ 626
+ S +Q
Sbjct: 123 DQHQGSYDEQ 132
Score = 33.9 bits (76), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 3/77 (3%)
Query: 579 GHGSGGGKNS-GGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPP--PPPPPP 635
G GSGGG+ GG +G G +G GD + G + G + +++ P P
Sbjct: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
Query: 636 PPPPAGGTGGKGKSGGR 652
P G G+G G R
Sbjct: 387 SRPSGGDFRGRGYGGER 403
Score = 30.8 bits (68), Expect = 8.5
Identities = 29/101 (28%), Positives = 40/101 (39%), Gaps = 4/101 (3%)
Query: 553 AGGHG-SGGGQRPGGGHGSGGGQGPGDGHG--SGGGKNSGGGKGSG-SGKGSDGDGERGK 608
+G +G SGG Q+ +G+ G QG G SG G+ + G SG S G + G
Sbjct: 4 SGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGY 63
Query: 609 SLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKS 649
S Y + S QQ +G GG+ S
Sbjct: 64 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPS 104
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 77.8 bits (190), Expect = 6e-14
Identities = 51/144 (35%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Query: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
G NFG N QG Q G G N G N SG G GS+ G S S G+ S
Sbjct: 200 GPPNFGT--NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
Query: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG 583
G + G S G SG + G + G G+ GG R G S G G G+
Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
Query: 584 GGKNSGGGKGSGSGKGSDGDGERG 607
GG SGGG G G G+ RG
Sbjct: 318 GG--SGGGNGHKPGCEKPGNEARG 339
Score = 69.7 bits (169), Expect = 2e-11
Identities = 51/177 (28%), Positives = 68/177 (38%), Gaps = 14/177 (7%)
Query: 450 PNNGARLSSEVSGSGSGNFGEEGNPQG--KEDQEGSGGDYMPMNNWGSGNGRGSGG-GQG 506
PN G V+ G G+ +G GSGG +N G G+G SG G G
Sbjct: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG---SSNSGGGSGSQSGSSGSG 258
Query: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
SNG ++ SSGG+ GS GG G+ G G ++ G +G G
Sbjct: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHG 318
Query: 567 GHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSK 623
G G G G P G G + GSG+ + E + F K +SK
Sbjct: 319 GSGGGNGHKP--------GCEKPGNEARGSGESGIQNSETSPGMFNFDTFWKNFKSK 367
Score = 67.0 bits (162), Expect = 1e-10
Identities = 61/185 (32%), Positives = 72/185 (38%), Gaps = 46/185 (24%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG--------GQGSNG- 509
E SG G G FG +G G + Q GG P + GN GS G GQG NG
Sbjct: 143 ETSG-GHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
Query: 510 --------QGS----------------------SSHSSGGNQCSGEGQGSR---GGQGSN 536
QG+ S S GG+ SG G GS+ G GSN
Sbjct: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
Query: 537 GQGSGGNQCSRDGQGTAGGHGSGG--GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGS 594
G + G+ G++ G SGG G G GS G G GS G +SG GS
Sbjct: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS 320
Query: 595 GSGKG 599
G G G
Sbjct: 321 GGGNG 325
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/172 (31%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGS---- 512
+ G G GN G G P S G + MN G+ G+G GG G+N QG+
Sbjct: 157 LGGQGQGNPGGLGTPWVHGYPGNSAGSF-GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
Query: 513 ---SSHSSGGNQ-CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG---GGQRPG 565
S +S N+ C+ GG SN G G+Q G G+ G + +G GG G
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
Query: 566 GGHG--SGGGQGPGDGHGSG----GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
G SGG G G+ G G S G +GS G+ G G K
Sbjct: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
Score = 63.9 bits (154), Expect = 9e-10
Identities = 56/200 (28%), Positives = 84/200 (42%), Gaps = 21/200 (10%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
+G +G+ E QG + G+G +P +G+ + G+ G+ ++ G++ H G
Sbjct: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQ 116
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG--GGQG--- 575
G+ +GS QG G+ + + T+GGHG G Q GG G G GG G
Sbjct: 117 AEDVIRHGADAVRGS-WQGVPGHNGAWE---TSGGHGIFGSQGGLGGQGQGNPGGLGTPW 172
Query: 576 ----PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPP 631
PG+ GS G G G G G G + + +G + S Q +
Sbjct: 173 VHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNE----- 227
Query: 632 PPPPPPPPAGGTGGKGKSGG 651
PPP+G GG SGG
Sbjct: 228 -GCTNPPPSGSGGGSSNSGG 246
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 77.8 bits (190), Expect = 6e-14
Identities = 51/144 (35%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Query: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
G NFG N QG Q G G N G N SG G GS+ G S S G+ S
Sbjct: 200 GPPNFGT--NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
Query: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG 583
G + G S G SG + G + G G+ GG R G S G G G+
Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
Query: 584 GGKNSGGGKGSGSGKGSDGDGERG 607
GG SGGG G G G+ RG
Sbjct: 318 GG--SGGGNGHKPGCEKPGNEARG 339
Score = 73.9 bits (180), Expect = 9e-13
Identities = 53/156 (33%), Positives = 66/156 (42%), Gaps = 8/156 (5%)
Query: 450 PNNGARLSSEVSGSGSGNFGEEGNPQG--KEDQEGSGGDYMPMNNWGSGNGRGSGG-GQG 506
PN G V+ G G+ +G GSGG +N G G+G SG G G
Sbjct: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG---SSNSGGGSGSQSGSSGSG 258
Query: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
SNG ++ SSGG+ GS GG S+G SG + SR G+ GS G G
Sbjct: 259 SNGDNNNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGN 316
Query: 567 GHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG 602
GSGGG G G G + G G+ G G
Sbjct: 317 HGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQG 352
Score = 67.0 bits (162), Expect = 1e-10
Identities = 61/185 (32%), Positives = 72/185 (38%), Gaps = 46/185 (24%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG--------GQGSNG- 509
E SG G G FG +G G + Q GG P + GN GS G GQG NG
Sbjct: 143 ETSG-GHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
Query: 510 --------QGS----------------------SSHSSGGNQCSGEGQGSR---GGQGSN 536
QG+ S S GG+ SG G GS+ G GSN
Sbjct: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
Query: 537 GQGSGGNQCSRDGQGTAGGHGSGG--GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGS 594
G + G+ G++ G SGG G G GS G G GS G +SG GS
Sbjct: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS 320
Query: 595 GSGKG 599
G G G
Sbjct: 321 GGGNG 325
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/172 (31%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGS---- 512
+ G G GN G G P S G + MN G+ G+G GG G+N QG+
Sbjct: 157 LGGQGQGNPGGLGTPWVHGYPGNSAGSF-GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
Query: 513 ---SSHSSGGNQ-CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG---GGQRPG 565
S +S N+ C+ GG SN G G+Q G G+ G + +G GG G
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
Query: 566 GGHG--SGGGQGPGDGHGSG----GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
G SGG G G+ G G S G +GS G+ G G K
Sbjct: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
Score = 64.7 bits (156), Expect = 5e-10
Identities = 46/142 (32%), Positives = 57/142 (40%), Gaps = 13/142 (9%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
SG GS N G Q GS GD NN GS +G S G G SS S GN
Sbjct: 237 SGGGSSNSGGGSGSQSGSSGSGSNGD----NNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGH 580
SG +G G + S G +G + G GG G G G +PG +G G+
Sbjct: 293 --SGGSRGDSGSESSWGSSTGSS------SGNHGGSGGGNGHKPGCEKPGNEARGSGES- 343
Query: 581 GSGGGKNSGGGKGSGSGKGSDG 602
G G + G + + S G
Sbjct: 344 GIQGFRGQGVSSNMRNSETSPG 365
Score = 60.1 bits (144), Expect = 1e-08
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 41/210 (19%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS---- 516
+G +G+ E QG + G+G +P +G+ + G+ G+ ++ G++ H
Sbjct: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQ 116
Query: 517 ------SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
G + G QG G G+ T+GGHG G Q GG G
Sbjct: 117 AEDVIRHGADAVRGSWQGVPGHNGA--------------WETSGGHGIFGSQGGLGGQGQ 162
Query: 571 G--GGQG-------PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQ 621
G GG G PG+ GS G G G G G G + + +G +
Sbjct: 163 GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRA 222
Query: 622 SKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
S Q + PPP+G GG SGG
Sbjct: 223 SNQNE------GCTNPPPSGSGGGSSNSGG 246
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 77.8 bits (190), Expect = 6e-14
Identities = 51/144 (35%), Positives = 59/144 (40%), Gaps = 4/144 (2%)
Query: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
G NFG N QG Q G G N G N SG G GS+ G S S G+ S
Sbjct: 200 GPPNFGT--NTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS 257
Query: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSG 583
G + G S G SG + G + G G+ GG R G S G G G+
Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317
Query: 584 GGKNSGGGKGSGSGKGSDGDGERG 607
GG SGGG G G G+ RG
Sbjct: 318 GG--SGGGNGHKPGCEKPGNEARG 339
Score = 75.1 bits (183), Expect = 4e-13
Identities = 54/166 (32%), Positives = 69/166 (41%), Gaps = 8/166 (4%)
Query: 450 PNNGARLSSEVSGSGSGNFGEEGNPQG--KEDQEGSGGDYMPMNNWGSGNGRGSGG-GQG 506
PN G V+ G G+ +G GSGG +N G G+G SG G G
Sbjct: 202 PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG---SSNSGGGSGSQSGSSGSG 258
Query: 507 SNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
SNG ++ SSGG+ GS GG S+G SG + SR G+ GS G G
Sbjct: 259 SNGDNNNGSSSGGSSSGSSSGGSSGG--SSGGSSGNSGGSRGDSGSESSWGSSTGSSSGN 316
Query: 567 GHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKK 612
GSGGG G G G + G G+ G G + + K
Sbjct: 317 HGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISK 362
Score = 67.0 bits (162), Expect = 1e-10
Identities = 61/185 (32%), Positives = 72/185 (38%), Gaps = 46/185 (24%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG--------GQGSNG- 509
E SG G G FG +G G + Q GG P + GN GS G GQG NG
Sbjct: 143 ETSG-GHGIFGSQGG-LGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGG 200
Query: 510 --------QGS----------------------SSHSSGGNQCSGEGQGSR---GGQGSN 536
QG+ S S GG+ SG G GS+ G GSN
Sbjct: 201 PPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSN 260
Query: 537 GQGSGGNQCSRDGQGTAGGHGSGG--GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGS 594
G + G+ G++ G SGG G G GS G G GS G +SG GS
Sbjct: 261 GDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGS 320
Query: 595 GSGKG 599
G G G
Sbjct: 321 GGGNG 325
Score = 65.9 bits (159), Expect = 2e-10
Identities = 54/172 (31%), Positives = 70/172 (40%), Gaps = 21/172 (12%)
Query: 460 VSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ---GSNGQGS---- 512
+ G G GN G G P S G + MN G+ G+G GG G+N QG+
Sbjct: 157 LGGQGQGNPGGLGTPWVHGYPGNSAGSF-GMNPQGAPWGQGGNGGPPNFGTNTQGAVAQP 215
Query: 513 ---SSHSSGGNQ-CSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSG---GGQRPG 565
S +S N+ C+ GG SN G G+Q G G+ G + +G GG G
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSG 275
Query: 566 GGHG--SGGGQGPGDGHGSG----GGKNSGGGKGSGSGKGSDGDGERGKSLK 611
G SGG G G+ G G S G +GS G+ G G K
Sbjct: 276 SSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHK 327
Score = 65.5 bits (158), Expect = 3e-10
Identities = 52/153 (33%), Positives = 61/153 (39%), Gaps = 20/153 (13%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGN 520
SG GS N G Q GS GD NN GS +G S G G SS S GN
Sbjct: 237 SGGGSSNSGGGSGSQSGSSGSGSNGD----NNNGSSSGGSSSGSSSGGSSGGSSGGSSGN 292
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPG----GGHGSGGGQGP 576
SG +G G + S G +G + G GG G G G +PG G G G+
Sbjct: 293 --SGGSRGDSGSESSWGSSTGSS------SGNHGGSGGGNGHKPGCEKPGNEARGSGESG 344
Query: 577 GDGHGSGGGKNSGGGKGSGSGK---GSDGDGER 606
G G G +S + S G G GD R
Sbjct: 345 IQGF-RGQGVSSNMREISKEGNRLLGGSGDNYR 376
Score = 60.1 bits (144), Expect = 1e-08
Identities = 55/210 (26%), Positives = 80/210 (38%), Gaps = 41/210 (19%)
Query: 461 SGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHS---- 516
+G +G+ E QG + G+G +P +G+ + G+ G+ ++ G++ H
Sbjct: 59 AGGAAGSKVSEALGQGTREAVGTGVRQVP--GFGAADALGNRVGEAAHALGNTGHEIGRQ 116
Query: 517 ------SGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
G + G QG G G+ T+GGHG G Q GG G
Sbjct: 117 AEDVIRHGADAVRGSWQGVPGHNGA--------------WETSGGHGIFGSQGGLGGQGQ 162
Query: 571 G--GGQG-------PGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQ 621
G GG G PG+ GS G G G G G G + + +G +
Sbjct: 163 GNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRA 222
Query: 622 SKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
S Q + PPP+G GG SGG
Sbjct: 223 SNQNE------GCTNPPPSGSGGGSSNSGG 246
Score = 49.7 bits (117), Expect = 2e-05
Identities = 46/160 (28%), Positives = 61/160 (38%), Gaps = 12/160 (7%)
Query: 446 PAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQ 505
P G+ S SGS SG+ G N G + S G ++ G +G SGG
Sbjct: 233 PPSGSGGGSSNSGGGSGSQSGSSGSGSN--GDNNNGSSSGGSSSGSSSGGSSGGSSGGSS 290
Query: 506 GSNG--QGSSSHSSGGNQCSGEGQGSRGGQ-GSNGQGSGGNQCSRDGQGTAGGHGSGGGQ 562
G++G +G S S +G G+ GG G NG G C + G A G G G Q
Sbjct: 291 GNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPG---CEKPG-NEARGSGESGIQ 346
Query: 563 RPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG 602
G G G + G G G + + S G
Sbjct: 347 ---GFRGQGVSSNMREISKEGNRLLGGSGDNYRNSETSPG 383
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 77.4 bits (189), Expect = 8e-14
Identities = 66/184 (35%), Positives = 76/184 (41%), Gaps = 37/184 (20%)
Query: 457 SSEVSGSGSGNFGE-EGNPQGKEDQEGSGGDYMPMNNWGSGNGRGS--GGGQGSNGQGSS 513
SS+ SGSGNFG G G D G GG++ +G G G G G G NG G+
Sbjct: 191 SSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGND 250
Query: 514 S-HSSGGNQCSGEGQG-SRGGQGSNGQGSG-GNQCSRDGQGTAGGHGSGGGQRPGGGHGS 570
+ GG SG +G GGQG QGSG G S D GG G GGG G G
Sbjct: 251 GGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGS--GSNFGG 308
Query: 571 GGGQ-------------GPGDGHGSGGGKNSG---------------GGKGSGSGKGSDG 602
GG GP G G+ GG++SG GG G S S G
Sbjct: 309 GGSYNDFGNYNNQSSNFGPMKG-GNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYG 367
Query: 603 DGER 606
G R
Sbjct: 368 SGRR 371
Score = 59.7 bits (143), Expect = 2e-08
Identities = 38/95 (40%), Positives = 44/95 (46%), Gaps = 10/95 (10%)
Query: 523 SGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAG---GHGSGGGQRPGGGHGSGG----GQG 575
+ Q R G G+ G G GG D G G G G GG R GGG+G G G G
Sbjct: 189 ASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFG 248
Query: 576 PGDGHGSGGGKNSGGGKGSGS---GKGSDGDGERG 607
G+G GG SGG +G GS G G+ G G G
Sbjct: 249 NDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGG 283
>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
isoform d [Homo sapiens]
Length = 756
Score = 74.7 bits (182), Expect = 5e-13
Identities = 74/287 (25%), Positives = 103/287 (35%), Gaps = 76/287 (26%)
Query: 529 SRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNS 588
+RGG G G+G GG + +G GG+ GG Q GGG G GG GG N
Sbjct: 511 NRGGGGFRGRGGGGGFQRYENRGPPGGN-RGGFQNRGGGSGGGGNYR--------GGFNR 561
Query: 589 GGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPP---PPPPPAGGTGG 645
GG G + + + + S + SY Q Q PPPP PP PPPPP+
Sbjct: 562 SGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPS----- 616
Query: 646 KGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRP 705
AR P A ++++ + P
Sbjct: 617 ----------------------------------YSPARNPPGASTYNKNSNIP--GSSA 640
Query: 706 GVATPLVSSSDYMPMAPQNVSASKKRHSRSPFED---SRGYMMMFPRVSPPPAPSPPKAP 762
+TP VSS Y P P +S+ P+ S+GY +PPP P PP A
Sbjct: 641 NTSTPTVSS--YSPPQPS--------YSQPPYNQGGYSQGY------TAPPPPPPPPPAY 684
Query: 763 DTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYF 809
+ S + + Y P P Q ++ W+ Y+
Sbjct: 685 NYG----SYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYY 727
Score = 48.1 bits (113), Expect = 5e-05
Identities = 44/174 (25%), Positives = 54/174 (31%), Gaps = 12/174 (6%)
Query: 482 GSGGDYM-------PMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGE-GQGSRGGQ 533
G GG + P N G RG G G G N +G + S GG G +R
Sbjct: 521 GGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNN 580
Query: 534 GSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKG 593
SN +GS + Q+P + P N G
Sbjct: 581 NSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSA 640
Query: 594 SGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKG 647
+ S S + Y Q Q PPPPPPPPPA G G
Sbjct: 641 NTSTPTVSSYSPPQPSYSQPPY----NQGGYSQGYTAPPPPPPPPPAYNYGSYG 690
>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
isoform a [Homo sapiens]
Length = 856
Score = 74.7 bits (182), Expect = 5e-13
Identities = 74/287 (25%), Positives = 103/287 (35%), Gaps = 76/287 (26%)
Query: 529 SRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNS 588
+RGG G G+G GG + +G GG+ GG Q GGG G GG GG N
Sbjct: 611 NRGGGGFRGRGGGGGFQRYENRGPPGGN-RGGFQNRGGGSGGGGNYR--------GGFNR 661
Query: 589 GGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPP---PPPPPAGGTGG 645
GG G + + + + S + SY Q Q PPPP PP PPPPP+
Sbjct: 662 SGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPS----- 716
Query: 646 KGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRP 705
AR P A ++++ + P
Sbjct: 717 ----------------------------------YSPARNPPGASTYNKNSNIP--GSSA 740
Query: 706 GVATPLVSSSDYMPMAPQNVSASKKRHSRSPFED---SRGYMMMFPRVSPPPAPSPPKAP 762
+TP VSS Y P P +S+ P+ S+GY +PPP P PP A
Sbjct: 741 NTSTPTVSS--YSPPQPS--------YSQPPYNQGGYSQGY------TAPPPPPPPPPAY 784
Query: 763 DTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYF 809
+ S + + Y P P Q ++ W+ Y+
Sbjct: 785 NYG----SYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYY 827
Score = 48.1 bits (113), Expect = 5e-05
Identities = 44/174 (25%), Positives = 54/174 (31%), Gaps = 12/174 (6%)
Query: 482 GSGGDYM-------PMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGE-GQGSRGGQ 533
G GG + P N G RG G G G N +G + S GG G +R
Sbjct: 621 GGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNN 680
Query: 534 GSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKG 593
SN +GS + Q+P + P N G
Sbjct: 681 NSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSA 740
Query: 594 SGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKG 647
+ S S + Y Q Q PPPPPPPPPA G G
Sbjct: 741 NTSTPTVSSYSPPQPSYSQPPY----NQGGYSQGYTAPPPPPPPPPAYNYGSYG 790
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 73.9 bits (180), Expect = 9e-13
Identities = 62/202 (30%), Positives = 72/202 (35%), Gaps = 43/202 (21%)
Query: 446 PAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSG--- 502
P P GAR G +G G G G GG + P G G G SG
Sbjct: 717 PPPPPFRGARGGRSGGGPPNGRGGPGGGMVG-------GGGHRPHEGPGGGMGNSSGHRP 769
Query: 503 --GGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGG 560
G G G G H G G G G R +G G SGG+ R +G GG G+GG
Sbjct: 770 HEGPGGGMGSGHRPHEGPGGSMGGGG-GHRPHEGPGGGISGGSG-HRPHEGPGGGMGAGG 827
Query: 561 GQRP----GGGHGSGGGQGPGDGHGSGGGK-------------------------NSGGG 591
G RP GG G GG P +G G GG + G G
Sbjct: 828 GHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGPG 887
Query: 592 KGSGSGKGSDGDGERGKSLKKR 613
G G +G DG G + R
Sbjct: 888 HGGGGHRGHDGGHSHGGDMSNR 909
Score = 66.6 bits (161), Expect = 1e-10
Identities = 78/278 (28%), Positives = 91/278 (32%), Gaps = 62/278 (22%)
Query: 436 LAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQE-------GSGGDYM 488
L P P P P + G G G G P G GGD
Sbjct: 620 LGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPF 679
Query: 489 ------PMNNWGSGNGRGSGGG---QGSNGQGSSS--------HSSGGNQCSGEGQGSRG 531
PM G G G G +G G+G + + G + G RG
Sbjct: 680 WDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRG 739
Query: 532 GQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQR----PGGGHGS--------GGGQGPGDG 579
G G G GG+ R +G GG G+ G R PGGG GS GG G G G
Sbjct: 740 GPGGGMVGGGGH---RPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGG 796
Query: 580 H----GSGGGKNSGGG----KGSGSGKGSDG--------DGERGKSLKKRSYFGKLTQSK 623
H G GGG + G G +G G G G+ G G G S R + G
Sbjct: 797 HRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGP 856
Query: 624 QQQMPPPPP-------PPPPPPPAGGTGGKGKSGGRFR 654
P P PPP G G G GG R
Sbjct: 857 HGHRPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHR 894
Score = 62.4 bits (150), Expect = 3e-09
Identities = 65/211 (30%), Positives = 74/211 (35%), Gaps = 35/211 (16%)
Query: 412 GRLHLPRGRRSRRAVSVPASFFR--RLAPSPARPRHPAEAPNNGARLSSEVSGSG----S 465
G H RG R P FR R S P + P G V G G
Sbjct: 701 GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGM-----VGGGGHRPHE 755
Query: 466 GNFGEEGNPQGKEDQEGSGGD----YMPMNNWGSGNGRGSG-------GGQGSNGQGSSS 514
G G GN G EG GG + P G G G G GG S G G
Sbjct: 756 GPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRP 815
Query: 515 HSS-GGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGG 573
H GG +G G G G + GSGG++ +G G G HG P GH
Sbjct: 816 HEGPGGGMGAGGGHRPHEGPGGSMGGSGGHR-PHEGPGHGGPHGHRPHDVP--GHRGHDH 872
Query: 574 QGP---------GDGHGSGGGKNSGGGKGSG 595
+GP G GHG GG + GG G
Sbjct: 873 RGPPPHEHRGHDGPGHGGGGHRGHDGGHSHG 903
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 73.6 bits (179), Expect = 1e-12
Identities = 50/166 (30%), Positives = 72/166 (43%), Gaps = 28/166 (16%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQ 521
G G G EEG +G+E+ EG G + G G G G G+G +G G +
Sbjct: 874 GEGEGE-EEEGEGEGEEEGEGEGEE-----EEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927
Query: 522 CSGEGQGSRG-GQGSNGQGSG--------GNQCSRDGQGTAGGHGSG------GGQRPGG 566
GEG+ G G+G +G+G G G + +G+G G G G G + G
Sbjct: 928 GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGE 987
Query: 567 GHG-------SGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGE 605
G G G +G G+ G G G+ G+ G +G +G+GE
Sbjct: 988 GEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE 1033
Score = 67.4 bits (163), Expect = 8e-11
Identities = 45/151 (29%), Positives = 66/151 (43%), Gaps = 16/151 (10%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSN----GQGSSS 514
E G G G EE +G+ ++EG G+ G G G G G+G G+G
Sbjct: 851 EEEGEGKG---EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Query: 515 HSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQ 574
G + GEG+G G+ G+G +G+G G G G G+ G +
Sbjct: 908 GEGEGEEEEGEGKGEEEGEEGEGEGE-----EEEGEG-EGEDGEGEGEEEEGEWEGEEEE 961
Query: 575 GPGDGHGSGGGKNSGGGKGSGSGKGSDGDGE 605
G G+G G G+ G +G G G+ +G+GE
Sbjct: 962 GEGEGEEEGEGE---GEEGEGEGEEEEGEGE 989
Score = 65.5 bits (158), Expect = 3e-10
Identities = 50/175 (28%), Positives = 71/175 (40%), Gaps = 17/175 (9%)
Query: 448 EAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGS 507
E G + G G EE E++EG G + G G+G G+
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Query: 508 NGQGSSSHSSG-GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTA-GGHGSGGGQRPG 565
G+ G G + GEG+G G+G + G + +G+G G G G+ G
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925
Query: 566 -GGHGSG---GGQGPG-DGHGSG--------GGKNSGGGKG--SGSGKGSDGDGE 605
G G G G+G G DG G G G + G G+G G G+G +G+GE
Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980
Score = 63.9 bits (154), Expect = 9e-10
Identities = 47/171 (27%), Positives = 68/171 (39%), Gaps = 10/171 (5%)
Query: 448 EAPNNGARLSSEVSGSGSGNF-----GEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR-GS 501
E G E G G G GEE +GK ++EG G+ G G G G
Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 945
Query: 502 GGGQGSNGQ--GSSSHSSGGNQCSGEGQGSRG-GQGSNGQGSG-GNQCSRDGQGTAGGHG 557
G G+ G+ G G + GEG+G G G+G +G G G + + +G G G
Sbjct: 946 GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEG 1005
Query: 558 SGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGK 608
G+ G G +G +G G G+ G + +G+GE +
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENR 1056
Score = 60.8 bits (146), Expect = 8e-09
Identities = 47/166 (28%), Positives = 68/166 (40%), Gaps = 24/166 (14%)
Query: 448 EAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGS 507
E G E G G EEG + +E++E G+ G G+
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE------------EEEGEGEEE 845
Query: 508 NGQGSSSHSSGGNQCSGE-GQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGG 566
G+G G + GE G+G +G G+G G + +G+G G G G + G
Sbjct: 846 EGEGEEEEGEGKGEEEGEEGEGEE--EGEEGEGEGEEE-EGEGEGEEEGEGE-GEEEEGE 901
Query: 567 GHGSGGGQGPG-DGHGSGGGKNSG------GGKGSGSGKGSDGDGE 605
G G G+G G + G G G+ G G + G G+G DG+GE
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947
Score = 58.2 bits (139), Expect = 5e-08
Identities = 44/153 (28%), Positives = 65/153 (42%), Gaps = 16/153 (10%)
Query: 470 EEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGG----GQGSNGQGS---SSHSSGGNQC 522
E + K ++EG G+ G G + GG G+ G+G G +
Sbjct: 779 ERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838
Query: 523 SGEGQGSRG-GQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDG-- 579
GEG+ G G+ G+G G + +G+G G G G G G +G G+G
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEE-GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Query: 580 -HGSGGGKNSGGGKG---SGSGKGSDGDGERGK 608
G G G+ G G+G G GKG + +GE G+
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEE-EGEEGE 929
Score = 47.4 bits (111), Expect = 9e-05
Identities = 35/148 (23%), Positives = 58/148 (39%), Gaps = 10/148 (6%)
Query: 466 GNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGS--------GGGQGSNGQGSSSHSS 517
G+ EE +G+ +EG G + G + G +G G+G +
Sbjct: 743 GDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802
Query: 518 GGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPG 577
G + EG GG+ G+G + +G+G G G + G G G+G
Sbjct: 803 GRGEEKEEGGEVEGGEVEEGKGEREEE-EEEGEGEEE-EGEGEEEEGEGEEEEGEGKGEE 860
Query: 578 DGHGSGGGKNSGGGKGSGSGKGSDGDGE 605
+G G + G+G G + +G+GE
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGE 888
Score = 47.0 bits (110), Expect = 1e-04
Identities = 34/137 (24%), Positives = 55/137 (40%), Gaps = 10/137 (7%)
Query: 470 EEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGS 529
EEG+ + +E++EG G + G G G + G + GE +G
Sbjct: 741 EEGDREEEEEKEGEGKE--------EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGD 792
Query: 530 RGGQGSNGQGSGGNQCSRDGQGTAGGH-GSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNS 588
+G +G + G + +G GG G G+R G + G+G G
Sbjct: 793 QG-EGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851
Query: 589 GGGKGSGSGKGSDGDGE 605
G+G G +G +G+GE
Sbjct: 852 EEGEGKGEEEGEEGEGE 868
Score = 38.5 bits (88), Expect = 0.041
Identities = 31/159 (19%), Positives = 58/159 (36%), Gaps = 7/159 (4%)
Query: 470 EEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQ-- 527
E+G+ + + + GG+ G G + +G G + GE +
Sbjct: 716 EQGHQKERNQEMEEGGE----EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKE 771
Query: 528 -GSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGK 586
G R + G+ G + G+G G ++ GG GG G G +
Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831
Query: 587 NSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
G + G G+ +G+GE + K G+ + +++
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870
Score = 35.0 bits (79), Expect = 0.45
Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 23/160 (14%)
Query: 469 GEEGNPQGKEDQEGSGG-DYMPMNNWGSGNGRGSGGG---QGSNGQGSSSHSSGGNQCSG 524
GE+ +G+ ++ G G + W +G QG + + GG + G
Sbjct: 677 GEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG 736
Query: 525 EGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRP----GGGHGSG---GGQGPG 577
EG+ G + + G + +G+ G G+R G G G QG G
Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEG 796
Query: 578 ---DGHGSGGGKNSGG---------GKGSGSGKGSDGDGE 605
+ G G K GG GKG + +G+GE
Sbjct: 797 EEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE 836
Score = 33.1 bits (74), Expect = 1.7
Identities = 48/242 (19%), Positives = 78/242 (32%), Gaps = 54/242 (22%)
Query: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
G G EG G ++ SG ++ W G +
Sbjct: 645 GEAEDGPEGRGDGTCEEGSSGAEH-----W------------------QDEEREKGEKDK 681
Query: 524 GEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGH-GSGGGQGPGDGHGS 582
G G+ R G+G RDG+ G Q+ GG + G+G
Sbjct: 682 GRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEE 741
Query: 583 GGGK---NSGGGKGSGSGKGSDGDGERGK---SLKKRSYFGKLTQSKQQQMPPPPPPPPP 636
G + G+G G+G + +GER K KK GK + +++
Sbjct: 742 EGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE----------- 790
Query: 637 PPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDE 696
G G+G+ G +E +E EV+ E+ EG + +E
Sbjct: 791 -----GDQGEGEEE--------ETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE 837
Query: 697 DD 698
++
Sbjct: 838 EE 839
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 72.4 bits (176), Expect = 3e-12
Identities = 121/473 (25%), Positives = 143/473 (30%), Gaps = 83/473 (17%)
Query: 438 PSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEG--------NPQGKEDQEGSGGDYMP 489
P PA P P + S G+ GE G PQG + Q G G+
Sbjct: 806 PGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP-- 863
Query: 490 MNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDG 549
G +G G G G S G N G +G RG QG G R G
Sbjct: 864 ----GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGL-KGGRGTQGPPGATGFPGSAGRVG 918
Query: 550 Q-GTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG-DGERG 607
G AG G G G G G +G HG G + G G KG G DG+ G
Sbjct: 919 PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG 978
Query: 608 K--------SLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCV 659
+ +R G Q ++ MP P P P G TG G G +
Sbjct: 979 PDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPG 1038
Query: 660 DRGATKECKEAKEVKDAEIPEGAARGPHRARAFDE--DEDDPYVPMRPGVATPLVSSSDY 717
G E E P G P R A E D DP PG S
Sbjct: 1039 SNGPVGE-------PGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG--------SQG 1083
Query: 718 MPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPP--------PAPSPPKAPDTNKEDD 769
P P V A R SRG + PP P P P+ D D
Sbjct: 1084 APGTPGPVGAPGDAGQRGD-PGSRG------PIGPPGRAGKRGLPGPQGPRG-DKGDHGD 1135
Query: 770 SKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYV 829
D + F P P QG + +P PF P G
Sbjct: 1136 RGDRGQKGHRGFTGLQGLPGPPGPNGEQGSA---------GIPGPF--GPRGP------- 1177
Query: 830 PMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPP 882
PG G + N P P GS + G G P +P PP
Sbjct: 1178 ---PGPVGPSGKEG----NPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPP 1223
Score = 68.9 bits (167), Expect = 3e-11
Identities = 113/456 (24%), Positives = 144/456 (31%), Gaps = 33/456 (7%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNG 498
S P P EA N G G G G G P G G G+ P G
Sbjct: 622 SSGDPGKPGEAGNAGVPGQRGAPGK-DGEVGPSG-PVGPPGLAGERGEQGPPGPTGFQGL 679
Query: 499 RGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGGHG 557
G G G G+ G G G RG +G+ G+ G G +G AGGHG
Sbjct: 680 PGPPGPPGEGGKPGDQGVPGDPGAVGP-LGPRGERGNPGERGEPGITGLPGEKGMAGGHG 738
Query: 558 SGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFG 617
G + G G+ G GP G G + G G +G G GE+G G
Sbjct: 739 PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG--GIGEKGAE-------G 789
Query: 618 KLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAE 677
+ +P P PP PAG TG KG+ G R + RG +
Sbjct: 790 TAGNDGARGLPGPLG---PPGPAGPTGEKGEPGPRGLVGPPGSRG--NPGSRGENGPTGA 844
Query: 678 IPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPF 737
+ +GP + +P G P + P P V K
Sbjct: 845 VGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGP 904
Query: 738 EDSRGYMMMFPRVSPP-PAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGA-GAI-PKNPR 794
+ G+ RV PP PA +P A + D PG+ G + + P
Sbjct: 905 PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGD-----PGSHGRVGDRGPA 959
Query: 795 NPQGGSSSKSWSSYFSLPNP-FRSSPLGQNDNSEYVPMLPGKFLGRGL-----DKEVSYN 848
P GG K P P P G V M PG+ RG+
Sbjct: 960 GPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM-PGQRGERGMPGLPGPAGTPGK 1018
Query: 849 WDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKN 884
P A G PG G +P P N
Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054
Score = 65.1 bits (157), Expect = 4e-10
Identities = 129/521 (24%), Positives = 161/521 (30%), Gaps = 99/521 (19%)
Query: 437 APSPARPRHPAEAPNNGARLSSEVSG-----SGSGNFGEEGNPQGKEDQEGSGGDYMPMN 491
A P PR E N G R ++G +G G +G P+G G+ GD P
Sbjct: 703 AVGPLGPR--GERGNPGERGEPGITGLPGEKGMAGGHGPDG-PKGSPGPSGTPGDTGPPG 759
Query: 492 NWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQ- 550
G RG G G G G +G G+RG G G G+
Sbjct: 760 LQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGN-DGARGLPGPLGPPGPAGPTGEKGEP 818
Query: 551 ---------GTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSD 601
G+ G GS G P G G G QGP G G G KG G
Sbjct: 819 GPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQ 878
Query: 602 G----DGERGKSLKKRSYFGKLTQSKQQQMPP-------------PPPPPPPPPPAGGTG 644
G G G + G+ TQ PP PP P P PAG G
Sbjct: 879 GLAGSPGPHGPNGVPGLKGGRGTQG-----PPGATGFPGSAGRVGPPGPAGAPGPAGPLG 933
Query: 645 GKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMR 704
GK G G + V D P G GP D+ DP +
Sbjct: 934 EPGKEG---------PPGLRGDPGSHGRVGDRG-PAGPPGGPG-------DKGDPGEDGQ 976
Query: 705 PGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDT 764
PG P P + + + RG M P + P PA +P K T
Sbjct: 977 PG------------PDGPPGPAGTTGQRGIVGMPGQRGERGM-PGL-PGPAGTPGKVGPT 1022
Query: 765 NKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQN- 823
D PG+ P P+G + + P R +G+
Sbjct: 1023 GATGDKGPPGPVGP-----PGSNG-PVGEPGPEGPAGNDG--------TPGRDGAVGERG 1068
Query: 824 DNSEYVPM-LPGKFLGRGLDKEVSYNWDPKDAASK--PSGEGSFSKPGDGGSPSKPSDHE 880
D + P LPG G V P DA + P G PG G P
Sbjct: 1069 DRGDPGPAGLPGSQGAPGTPGPVGA---PGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQG 1125
Query: 881 PPKNKAKRPNRLSFITKGYK------IKPKPQKPTHEQREA 915
P +K +R KG++ P P P EQ A
Sbjct: 1126 PRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSA 1166
Score = 59.7 bits (143), Expect = 2e-08
Identities = 69/264 (26%), Positives = 92/264 (34%), Gaps = 34/264 (12%)
Query: 410 RRGRLHLP--RGRRSRRAVSVPASFFRRLAPSPAR----PRHPAEAPNNGARLSSEVSGS 463
+RG + +P RG R + PA ++ P+ A P P P + +
Sbjct: 991 QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEG 1050
Query: 464 GSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCS 523
+GN G G G + G GD P GS G+ G G+ G G
Sbjct: 1051 PAGNDGTPGR-DGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPI 1109
Query: 524 GEG-----------QGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGG 572
G QG RG +G +G G++ + +G G G G P G GS G
Sbjct: 1110 GPPGRAGKRGLPGPQGPRGDKGDHGDR--GDRGQKGHRGFTGLQGLPGPPGPNGEQGSAG 1167
Query: 573 GQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKKRSYFGKLTQSKQQQMPP-- 629
GP G G G +G+ G G G RG + PP
Sbjct: 1168 IPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGS-----------VGEAGPEGPPGE 1216
Query: 630 PPPPPPPPPPAGGTGGKGKSGGRF 653
P PP PP PP T G G +
Sbjct: 1217 PGPPGPPGPPGHLTAALGDIMGHY 1240
Score = 58.2 bits (139), Expect = 5e-08
Identities = 63/214 (29%), Positives = 79/214 (36%), Gaps = 18/214 (8%)
Query: 438 PSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGN 497
P P P P + + +G G G P+G + Q G G P+ + G
Sbjct: 362 PGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARG-PEGPQGQRGETGPPGPVGSPGLPG 420
Query: 498 GRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNG-QGSGGNQCSRDGQGTAGGH 556
G+ G G+ G S +SG GS G GS G QGS G Q R G G
Sbjct: 421 AIGTDGTPGAKGPTGSPGTSGP-------PGSAGPPGSPGPQGSTGPQGIRGQPGDPGVP 473
Query: 557 GSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYF 616
G G P G G G QGP G G + G G+ G GERG + R +
Sbjct: 474 GFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP--VGERG-APGNRGFP 530
Query: 617 GKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
G +P P P G +G KG G
Sbjct: 531 G------SDGLPGPKGAQGERGPVGSSGPKGSQG 558
Score = 56.6 bits (135), Expect = 1e-07
Identities = 64/211 (30%), Positives = 79/211 (37%), Gaps = 34/211 (16%)
Query: 466 GNFGEEG--NPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSG--GNQ 521
G G +G P G+E + G GD + G RG+ G +G G G G +
Sbjct: 486 GPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGER 545
Query: 522 CSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGH 580
G +G QG G+ G G +R G G G G P G G G GP
Sbjct: 546 GPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGP---P 602
Query: 581 GSGGGKNSGGGKGSGSGKGSDGD----GERGKS--LKKRSYFGK--------------LT 620
GS G + G G KGS GD GE G + +R GK L
Sbjct: 603 GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662
Query: 621 QSKQQQMPPPP------PPPPPPPPAGGTGG 645
+ +Q PP P P PP PP GG G
Sbjct: 663 GERGEQGPPGPTGFQGLPGPPGPPGEGGKPG 693
Score = 49.7 bits (117), Expect = 2e-05
Identities = 65/218 (29%), Positives = 77/218 (35%), Gaps = 20/218 (9%)
Query: 439 SPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNG 498
S P P E GAR +GN G +G P+GK G+ G+ GS
Sbjct: 556 SQGDPGRPGEPGLPGAR-------GLTGNPGVQG-PEGKLGPLGAPGEDGRPGPPGSIGI 607
Query: 499 RGSGGGQGSNGQGSSSHSSG--GNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGG 555
RG G G G SS G G + G RG G +G+ G G G G
Sbjct: 608 RGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV------GPPGL 661
Query: 556 HGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKK-- 612
G G Q P G G G GP G GG G G G G GERG ++
Sbjct: 662 AGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGE 721
Query: 613 RSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
G + P P P P+G G G G
Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPG 759
Score = 48.9 bits (115), Expect = 3e-05
Identities = 133/563 (23%), Positives = 174/563 (30%), Gaps = 126/563 (22%)
Query: 446 PAEAPNNGARLSSEVSGSGSGNFG-----EEGNP---------QGKEDQEGSGGDYMPMN 491
P P + S+ G G+ NFG ++G P +G+ G G P
Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144
Query: 492 NWGSGNGRGSGGGQGSNGQ-------------GSSSHSSGGN-------QCSG----EGQ 527
G G G QG +G+ G SH Q +G G
Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204
Query: 528 GSRGG--QGSNG----QGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHG 581
GS+ G GS G +G G Q + G G G G G P G GS G +GP G
Sbjct: 205 GSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPG 264
Query: 582 SGGGKNSGGGKGSGSGKGSDG----DGERGKSLKKRSYFGKLTQSKQQQMPPP-----PP 632
G G G GS G G G K K + + ++ P
Sbjct: 265 EDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324
Query: 633 PPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGA--ARGPHRAR 690
P P G G +G G R RL P+GA RG H
Sbjct: 325 PTGPMGAMGPLGPRGMPGERGRLG----------------------PQGAPGQRGAHG-- 360
Query: 691 AFDEDEDDPYVPMRPGVATPL-VSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPR 749
+P +PG PL + S P P + +R P E +G
Sbjct: 361 ----------MPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGP-EGPQGQRGETGP 409
Query: 750 VSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYF 809
P +P P A T+ +K + S PG+ P +P PQG +
Sbjct: 410 PGPVGSPGLPGAIGTDGTPGAK-GPTGSPGTSGPPGSAGPPGSP-GPQGSTG-------- 459
Query: 810 SLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGD 869
P R P P +PG F G K + P EG GD
Sbjct: 460 --PQGIRGQPGD--------PGVPG-FKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGD 508
Query: 870 GGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKPTHEQREADSSSDYVNMDFTKR 929
G+ P P + P F G P P+ E+ SS K
Sbjct: 509 PGTVGPPG----PVGERGAPGNRGF--PGSDGLPGPKGAQGERGPVGSSG-------PKG 555
Query: 930 ESNTPA-PSTQGLPDSWGIIAEP 951
P P GLP + G+ P
Sbjct: 556 SQGDPGRPGEPGLPGARGLTGNP 578
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 72.4 bits (176), Expect = 3e-12
Identities = 63/184 (34%), Positives = 80/184 (43%), Gaps = 34/184 (18%)
Query: 477 KEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSN 536
+ + G GG N+G G+ RG GG + G G S+ GG+ G G+G G G N
Sbjct: 197 QSSRSGRGG------NFGFGDSRGGGG---NFGPGPGSNFRGGSDGYGSGRGF--GDGYN 245
Query: 537 GQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPG---DGHGSGGGKNSGGGKG 593
G G G GG GG GGG G GG GPG G G GGG ++ GG
Sbjct: 246 GYGGG-----------PGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGN 294
Query: 594 SGSGKGSDGDGERGKSLKKRSYFGKLTQSK---QQQMPPPPPPPPPPPPAGGTGGKGKSG 650
GSG +D G ++ S +G + + M P P GG+GG G G
Sbjct: 295 YGSGNYND----FGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGP--GGSGGSGGYG 348
Query: 651 GRFR 654
GR R
Sbjct: 349 GRSR 352
Score = 62.4 bits (150), Expect = 3e-09
Identities = 55/169 (32%), Positives = 62/169 (36%), Gaps = 35/169 (20%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMP-----MNNWGSGNGRGSGGGQGSNGQGSS 513
EV S SG G G D G GG++ P G G G G G G NG G
Sbjct: 195 EVQSSRSGR----GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGG- 249
Query: 514 SHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGT-AGGHGSGGGQRPGGGHGSG- 571
G G G+ GG G G GG G G GG+G G GG +GSG
Sbjct: 250 ----------GPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGN 299
Query: 572 -----------GGQGPGDGHGSGGGKNSGGGKGSGS--GKGSDGDGERG 607
GP GG +N GG G G+ GS G G G
Sbjct: 300 YNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYG 348
Score = 50.1 bits (118), Expect = 1e-05
Identities = 37/106 (34%), Positives = 45/106 (42%), Gaps = 9/106 (8%)
Query: 508 NGQGSSSHSSGGNQCSGEGQGSRGGQGSN-----GQGSGGNQCSRDGQGTAGGH-GSGGG 561
NG + + Q E Q SR G+G N +G GGN G GG G G G
Sbjct: 178 NGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSG 237
Query: 562 QRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
+ G G+ GG G G G+ GG GG G G G G G +G
Sbjct: 238 RGFGDGYNGYGG---GPGGGNFGGSPGYGGGRGGYGGGGPGYGNQG 280
Score = 37.7 bits (86), Expect = 0.070
Identities = 35/102 (34%), Positives = 45/102 (44%), Gaps = 22/102 (21%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGN-GRGSGGGQGSNGQGSSSHSSGGN 520
G G +G +G G GG Y +N+G GN G G+ G+ Q S++ G
Sbjct: 270 GGGGPGYGNQGG--------GYGGGY---DNYGGGNYGSGNYNDFGNYNQQPSNY---GP 315
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQ 562
SG GSR G G GGN G G +GG G GG+
Sbjct: 316 MKSGNFGGSRNMGGPYG---GGNY----GPGGSGGSGGYGGR 350
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 72.4 bits (176), Expect = 3e-12
Identities = 63/184 (34%), Positives = 80/184 (43%), Gaps = 34/184 (18%)
Query: 477 KEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSN 536
+ + G GG N+G G+ RG GG + G G S+ GG+ G G+G G G N
Sbjct: 185 QSSRSGRGG------NFGFGDSRGGGG---NFGPGPGSNFRGGSDGYGSGRGF--GDGYN 233
Query: 537 GQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPG---DGHGSGGGKNSGGGKG 593
G G G GG GG GGG G GG GPG G G GGG ++ GG
Sbjct: 234 GYGGG-----------PGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGN 282
Query: 594 SGSGKGSDGDGERGKSLKKRSYFGKLTQSK---QQQMPPPPPPPPPPPPAGGTGGKGKSG 650
GSG +D G ++ S +G + + M P P GG+GG G G
Sbjct: 283 YGSGNYND----FGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGP--GGSGGSGGYG 336
Query: 651 GRFR 654
GR R
Sbjct: 337 GRSR 340
Score = 62.4 bits (150), Expect = 3e-09
Identities = 55/169 (32%), Positives = 62/169 (36%), Gaps = 35/169 (20%)
Query: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMP-----MNNWGSGNGRGSGGGQGSNGQGSS 513
EV S SG G G D G GG++ P G G G G G G NG G
Sbjct: 183 EVQSSRSGR----GGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGG- 237
Query: 514 SHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGT-AGGHGSGGGQRPGGGHGSG- 571
G G G+ GG G G GG G G GG+G G GG +GSG
Sbjct: 238 ----------GPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGN 287
Query: 572 -----------GGQGPGDGHGSGGGKNSGGGKGSGS--GKGSDGDGERG 607
GP GG +N GG G G+ GS G G G
Sbjct: 288 YNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYG 336
Score = 50.1 bits (118), Expect = 1e-05
Identities = 37/106 (34%), Positives = 45/106 (42%), Gaps = 9/106 (8%)
Query: 508 NGQGSSSHSSGGNQCSGEGQGSRGGQGSN-----GQGSGGNQCSRDGQGTAGGH-GSGGG 561
NG + + Q E Q SR G+G N +G GGN G GG G G G
Sbjct: 166 NGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSG 225
Query: 562 QRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
+ G G+ GG G G G+ GG GG G G G G G +G
Sbjct: 226 RGFGDGYNGYGG---GPGGGNFGGSPGYGGGRGGYGGGGPGYGNQG 268
Score = 37.7 bits (86), Expect = 0.070
Identities = 35/102 (34%), Positives = 45/102 (44%), Gaps = 22/102 (21%)
Query: 462 GSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGN-GRGSGGGQGSNGQGSSSHSSGGN 520
G G +G +G G GG Y +N+G GN G G+ G+ Q S++ G
Sbjct: 258 GGGGPGYGNQGG--------GYGGGY---DNYGGGNYGSGNYNDFGNYNQQPSNY---GP 303
Query: 521 QCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQ 562
SG GSR G G GGN G G +GG G GG+
Sbjct: 304 MKSGNFGGSRNMGGPYG---GGNY----GPGGSGGSGGYGGR 338
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 71.6 bits (174), Expect = 4e-12
Identities = 121/457 (26%), Positives = 146/457 (31%), Gaps = 88/457 (19%)
Query: 437 APSPARPRHPA-EAPNNGARLSSEVSG--SGSGNFGEEGNP--QGKEDQEGSGGDYMPMN 491
A P P PA E GA S G G GE G P QG + G+ G P
Sbjct: 640 AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699
Query: 492 NWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQG 551
G RGS G QG G + G + G +G G G G Q QG
Sbjct: 700 ERGFPGERGSPGAQGLQGPRGLPGTPGTD-------GPKGASGP--AGPPGAQGPPGLQG 750
Query: 552 TAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSL 610
G G+ G P G G G +GP G GG+ G G G++G+ GE G
Sbjct: 751 MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPP- 809
Query: 611 KKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEA 670
G + + P PP PAG G G G GA E EA
Sbjct: 810 ------GPAGSAGARGAPGERGETGPPGPAGFAGPPGADG---------QPGAKGEQGEA 854
Query: 671 KEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKK 730
+ DA P +GP A PG P P V+ K
Sbjct: 855 GQKGDAGAP--GPQGPSGA---------------PG------------PQGPTGVTGPKG 885
Query: 731 RHSRSPFEDSRGYMMMFPRVSPPPA---PSPPKAPDTNKEDDSKDNDSESDYMFMAPGAG 787
+ G+ RV PP + P PP P + +D K +S PG
Sbjct: 886 ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG----PPGRA 941
Query: 788 AIP--KNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEV 845
P + P P G P P G V LPG+ RG
Sbjct: 942 GEPGLQGPAGPPGEKGEPGDDGPSGAEGP--PGPQGLAGQRGIVG-LPGQRGERGFP--- 995
Query: 846 SYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPP 882
PSGE PG G+P D PP
Sbjct: 996 --------GLPGPSGE-----PGKQGAPGASGDRGPP 1019
Score = 67.4 bits (163), Expect = 8e-11
Identities = 58/207 (28%), Positives = 76/207 (36%), Gaps = 15/207 (7%)
Query: 450 PNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNG 509
P R+ S G G G P GK+ +G+ GD P G +G G G G
Sbjct: 899 PGAAGRVGPPGSNGNPGPPGPPG-PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957
Query: 510 QGSSSHSSGGNQCSGEGQGSRGGQGSNGQ----GSGGNQCSRDGQGTAGGHGSGGGQRPG 565
+ SG +G G QG GQ G G + R G G G G Q
Sbjct: 958 EPGDDGPSGA-------EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ--- 1007
Query: 566 GGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQ 625
G G+ G +GP G G G G G+DG R + + G+
Sbjct: 1008 GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067
Query: 626 QMPPPPPPPPPPPPAGGTGGKGKSGGR 652
P PP P P P G G +G++G +
Sbjct: 1068 GAPGPPGSPGPAGPTGKQGDRGEAGAQ 1094
Score = 63.5 bits (153), Expect = 1e-09
Identities = 119/490 (24%), Positives = 159/490 (32%), Gaps = 79/490 (16%)
Query: 438 PSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGN 497
P P P P P G +++++G F E+ +G G P G
Sbjct: 161 PGPPGPPGPPGPPGLGGNFAAQMAGG----FDEKAGGAQLGVMQGPMGPMGPRGPPGPAG 216
Query: 498 GRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGGH 556
G G QG+ G+ SG G G G G +G+ G G R G G
Sbjct: 217 APGPQGFQGNPGEPGEPGVSGPMGPRGP-PGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275
Query: 557 GSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-------GERGKS 609
G G G G G G G G G GS GS G GERG++
Sbjct: 276 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRT 335
Query: 610 LKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKE 669
G P P PP P PAGG G G G + + G T
Sbjct: 336 ----GPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK------GEAGPT----G 381
Query: 670 AKEVKDAEIPEG-----AARGPHRARAFDEDEDDPYV---PMRPGVATPLVSSSDYMPMA 721
A+ + A+ P G + GP A + P PG+A P
Sbjct: 382 ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPG 441
Query: 722 PQNVSA--SKKRHSRSP----FEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDS 775
PQ + K + P F+ +G P+ P PA P AP E+ +
Sbjct: 442 PQGATGPLGPKGQTGEPGIAGFKGEQG-----PKGEPGPA-GPQGAPGPAGEEGKRGARG 495
Query: 776 ESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNP----------FRSSPLGQNDN 825
E PG G P P +G ++ + L P + P G N +
Sbjct: 496 E-------PG-GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGD 547
Query: 826 SEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGE-GSFSKPGDGGSPSKPSDHEPPKN 884
PG+ GL P DA P G+ G PG+ G P P P+
Sbjct: 548 -------PGRPGEPGLPGARGLTGRPGDAG--PQGKVGPSGAPGEDGRPGPPG----PQG 594
Query: 885 KAKRPNRLSF 894
+P + F
Sbjct: 595 ARGQPGVMGF 604
Score = 60.5 bits (145), Expect = 1e-08
Identities = 60/205 (29%), Positives = 75/205 (36%), Gaps = 21/205 (10%)
Query: 437 APSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSG 496
A P R P G ++ V G G G G P G GS G P G
Sbjct: 1031 AGEPGREGSPGADGPPGRDGAAGVKGD-RGETGAVGAP-GAPGPPGSPG---PAGPTGKQ 1085
Query: 497 NGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGG 555
RG G QG G + + G QG +G +G G+ G G + + +G G
Sbjct: 1086 GDRGEAGAQGPMGPSGPAGARGI-------QGPQGPRGDKGEAGEPGERGLKGHRGFTGL 1138
Query: 556 HGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKKRS 614
G G P G G+ G GP G G G G+ G G G RG+S
Sbjct: 1139 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRS----- 1193
Query: 615 YFGKLTQSKQQQMPPPPPPPPPPPP 639
G+ + P PP PP PP P
Sbjct: 1194 --GETGPAGPPGNPGPPGPPGPPGP 1216
Score = 59.7 bits (143), Expect = 2e-08
Identities = 55/183 (30%), Positives = 68/183 (37%), Gaps = 18/183 (9%)
Query: 469 GEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQG 528
G G P GK+ G+ GD P G G G G G + G + +G +G
Sbjct: 999 GPSGEP-GKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGV-KG 1056
Query: 529 SRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNS 588
RG G+ G + G G G G G G G QGP G G +
Sbjct: 1057 DRGETGAVG--------APGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108
Query: 589 GGGKGSGSGKGSDGD-GERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKG 647
G +G KG G+ GERG LK F L Q +P PP P +G G G
Sbjct: 1109 QGPQGPRGDKGEAGEPGERG--LKGHRGFTGL-----QGLPGPPGPSGDQGASGPAGPSG 1161
Query: 648 KSG 650
G
Sbjct: 1162 PRG 1164
Score = 58.9 bits (141), Expect = 3e-08
Identities = 61/227 (26%), Positives = 71/227 (31%), Gaps = 21/227 (9%)
Query: 437 APSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSG 496
AP P P P +G P G G G P G
Sbjct: 871 APGPQGPTG-VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 929
Query: 497 NGRGSGGGQGSNGQGSSSHSSG--------GNQCSGEGQGSRGGQGSNGQ----GSGGNQ 544
RG G G G+ +G G+ +G G QG GQ G G +
Sbjct: 930 GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 989
Query: 545 CSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDG-D 603
R G G G G Q G G G GP G G G +GS G G D
Sbjct: 990 GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRD 1049
Query: 604 GERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
G G G ++ P P PP P PAG TG +G G
Sbjct: 1050 GAAGVK-------GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG 1089
Score = 57.0 bits (136), Expect = 1e-07
Identities = 66/226 (29%), Positives = 79/226 (34%), Gaps = 21/226 (9%)
Query: 438 PSPARPRH-PAEAPNNGAR-LSSEVSGSGS-GNFGEEGNP--QGKEDQEGSGGDYMPMNN 492
P PA P+ P A G R E G G G GE G P +G Q+G G
Sbjct: 473 PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 532
Query: 493 WGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDG--- 549
G G G G G+ G +G G G QG G + R G
Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR-PGDAGPQGKVGPSGAPGEDGRPGPPG 591
Query: 550 -QGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD----G 604
QG G G G P G +G G G G+ G + G G G G G
Sbjct: 592 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651
Query: 605 ERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSG 650
ERG+ G S Q +P PP PP G G G++G
Sbjct: 652 ERGEQ-------GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAG 690
Score = 53.9 bits (128), Expect = 9e-07
Identities = 119/462 (25%), Positives = 152/462 (32%), Gaps = 61/462 (13%)
Query: 443 PRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGR-GS 501
P P E GAR +G G+ G PQGK G+ G+ +GR G
Sbjct: 548 PGRPGEPGLPGAR-------GLTGRPGDAG-PQGKVGPSGAPGE----------DGRPGP 589
Query: 502 GGGQGSNGQGSSSHSSGGNQCSGEG--QGSRGGQGSNG----QGSGGNQCSRDGQGTAGG 555
G QG+ GQ G +GE G +G G+ G G G + G AG
Sbjct: 590 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649
Query: 556 HGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGD-GERGKSLKKRS 614
G G Q G G G GP G GG G G G G GERG ++ S
Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 709
Query: 615 YFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVK 674
+ Q + +P P P +G G G G +RGA +
Sbjct: 710 PGAQGLQG-PRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG 768
Query: 675 DA--EIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASK--- 729
D + PEGA G R P P PG A + P P + ++
Sbjct: 769 DVGEKGPEGAP-GKDGGRGL----TGPIGP--PGPAGANGEKGEVGPPGPAGSAGARGAP 821
Query: 730 -KRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGA 788
+R P G+ PP A P A E K + P
Sbjct: 822 GERGETGP-PGPAGF------AGPPGADGQPGAKGEQGEAGQKGDAGAPGP--QGPSGAP 872
Query: 789 IPKNP---RNPQGGSSSKSWSSYFSLPNPF-RSSPLGQNDNSEYVPMLPGKFLGRGLDKE 844
P+ P P+G ++ P R P G N N P PG G D
Sbjct: 873 GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGN----PGPPGPPGPSGKDGP 928
Query: 845 VSYNWD--PKDAASKPSGEGSFSKPGDGGSPSK--PSDHEPP 882
D P A +P +G PG+ G P PS E P
Sbjct: 929 KGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP 970
Score = 49.7 bits (117), Expect = 2e-05
Identities = 107/433 (24%), Positives = 142/433 (32%), Gaps = 46/433 (10%)
Query: 466 GNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGE 525
G G++G P +D G G P G RG G +G G G G
Sbjct: 101 GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPG- 159
Query: 526 GQGSRGGQGSNG-QGSGGNQCSRDGQG---TAGG------HGSGGGQRPGGGHGSGGGQG 575
G G G G G GGN ++ G AGG G G P G G G G
Sbjct: 160 NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219
Query: 576 PGDGHGSGGGKNSGGGKGSGSGKGSDG-------DGERGKSLKKRSYFGKLTQSKQQQMP 628
P G+ G G G +G G DGE GK K G + P
Sbjct: 220 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP-GKAGERGPPGPQGARGFP 278
Query: 629 PPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIP-EGAARGPH 687
P P G G G G + G+ E + +P E GP
Sbjct: 279 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPA 338
Query: 688 RARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMF 747
A ++ P PG P + P AP + +R P E ++G
Sbjct: 339 GAAGARGNDGQPGPAGPPGPVGP--AGGPGFPGAPGAKGEAGPTGARGP-EGAQG----- 390
Query: 748 PRVSP--PPAPSPPKA---PDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSS 802
PR P P +P P A P T+ +K + + + APG P+ P PQG +
Sbjct: 391 PRGEPGTPGSPGPAGASGNPGTDGIPGAK-GSAGAPGIAGAPGFPG-PRGPPGPQGATGP 448
Query: 803 KSWSSYFSLPN--PFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSG 860
P F+ Q E P P G ++ + A +P G
Sbjct: 449 LGPKGQTGEPGIAGFKGE---QGPKGEPGPAGPQGAPGPAGEE------GKRGARGEPGG 499
Query: 861 EGSFSKPGDGGSP 873
G PG+ G+P
Sbjct: 500 VGPIGPPGERGAP 512
Score = 40.8 bits (94), Expect = 0.008
Identities = 44/161 (27%), Positives = 53/161 (32%), Gaps = 21/161 (13%)
Query: 466 GNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGE 525
G+ G G P GK+ G G PM G RG G QG G + G G
Sbjct: 1074 GSPGPAG-PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1132
Query: 526 GQGSRGGQGSNGQ-GSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSG------------- 571
+G G QG G G G+Q + G +G G G P G G+
Sbjct: 1133 -RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG 1191
Query: 572 -----GGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
G GP G G G S G E+G
Sbjct: 1192 RSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG 1232
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,690,551
Number of Sequences: 37866
Number of extensions: 4141170
Number of successful extensions: 91831
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 853
Number of HSP's successfully gapped in prelim test: 908
Number of HSP's that attempted gapping in prelim test: 34414
Number of HSP's gapped (non-prelim): 25347
length of query: 1257
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1143
effective length of database: 13,930,794
effective search space: 15922897542
effective search space used: 15922897542
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.