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Search of human proteins with 4504377
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 724 0.0
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 687 0.0
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 664 0.0
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 493 e-140
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 456 e-128
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 297 1e-80
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 295 3e-80
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 271 5e-73
gi|4504417 major histocompatibility complex, class I-related [Ho... 223 3e-58
gi|24797067 major histocompatibility complex, class I, A precurs... 216 2e-56
gi|17986001 major histocompatibility complex, class I, B precurs... 215 4e-56
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 210 2e-54
gi|52630342 major histocompatibility complex, class I, C precurs... 206 2e-53
gi|4504415 major histocompatibility complex, class I, G precurso... 203 2e-52
gi|149158702 major histocompatibility complex, class I, F isofor... 202 3e-52
gi|149158698 major histocompatibility complex, class I, F isofor... 202 3e-52
gi|62912479 major histocompatibility complex, class I, E precurs... 201 6e-52
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 198 7e-51
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 140 1e-33
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 134 9e-32
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 127 2e-29
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 127 2e-29
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 6e-21
gi|149158700 major histocompatibility complex, class I, F isofor... 93 4e-19
gi|239740918 PREDICTED: similar to major histocompatibility comp... 88 1e-17
gi|4502649 CD1D antigen precursor [Homo sapiens] 88 1e-17
gi|239740920 PREDICTED: similar to major histocompatibility comp... 88 1e-17
gi|150418002 major histocompatibility complex, class II, DQ beta... 86 6e-17
gi|169168591 PREDICTED: similar to major histocompatibility comp... 85 8e-17
gi|239748788 PREDICTED: similar to major histocompatibility comp... 81 1e-15
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 724 bits (1870), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 240
AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 240
Query: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300
KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300
Query: 301 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 301 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 687 bits (1772), Expect = 0.0
Identities = 334/348 (95%), Positives = 334/348 (95%), Gaps = 14/348 (4%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 240
AYLERDCPAQLQQLLELGRGVLDQQ VTTLRCRALNYYPQNITMKWL
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQ--------------VTTLRCRALNYYPQNITMKWL 226
Query: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300
KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 227 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 286
Query: 301 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 287 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 664 bits (1713), Expect = 0.0
Identities = 324/348 (93%), Positives = 324/348 (93%), Gaps = 23/348 (6%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 97
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 98 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 157
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 240
AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL
Sbjct: 158 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 217
Query: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300
KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 218 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 277
Query: 301 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 278 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 493 bits (1270), Expect = e-140
Identities = 234/235 (99%), Positives = 235/235 (100%)
Query: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 233
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 145
Query: 234 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 293
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
Query: 294 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260
Score = 59.3 bits (142), Expect = 5e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 456 bits (1172), Expect = e-128
Identities = 220/235 (93%), Positives = 221/235 (94%), Gaps = 14/235 (5%)
Query: 114 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 173
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 174 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 233
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV TTLRCRALNYYPQ
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV--------------TTLRCRALNYYPQ 131
Query: 234 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 293
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 191
Query: 294 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 192 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246
Score = 59.3 bits (142), Expect = 5e-09
Identities = 31/52 (59%), Positives = 37/52 (71%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGY 52
MGPRARPALLLLMLLQTAVLQGRLL+SH+L + ++D + GY
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQSHTLQVILGCEMQEDNSTEGYWKYGY 52
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 297 bits (760), Expect = 1e-80
Identities = 143/144 (99%), Positives = 144/144 (100%)
Query: 205 QVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 264
+VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY
Sbjct: 113 KVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172
Query: 265 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 324
QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI
Sbjct: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 232
Query: 325 LFIILRKRQGSRGAMGHYVLAERE 348
LFIILRKRQGSRGAMGHYVLAERE
Sbjct: 233 LFIILRKRQGSRGAMGHYVLAERE 256
Score = 234 bits (597), Expect = 9e-62
Identities = 113/113 (100%), Positives = 113/113 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 295 bits (756), Expect = 3e-80
Identities = 142/143 (99%), Positives = 143/143 (100%)
Query: 206 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 265
+PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 26 LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 266 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 325
GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
Query: 326 FIILRKRQGSRGAMGHYVLAERE 348
FIILRKRQGSRGAMGHYVLAERE
Sbjct: 146 FIILRKRQGSRGAMGHYVLAERE 168
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 271 bits (694), Expect = 5e-73
Identities = 131/135 (97%), Positives = 132/135 (97%)
Query: 214 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 273
+H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP
Sbjct: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167
Query: 274 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 333
PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ
Sbjct: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227
Query: 334 GSRGAMGHYVLAERE 348
GSRGAMGHYVLAERE
Sbjct: 228 GSRGAMGHYVLAERE 242
Score = 234 bits (597), Expect = 9e-62
Identities = 113/113 (100%), Positives = 113/113 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 223 bits (567), Expect = 3e-58
Identities = 122/323 (37%), Positives = 185/323 (57%), Gaps = 5/323 (1%)
Query: 11 LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEP 70
LL L+ +++ R+HSL Y +G S+ G+ F ++GYVD YD +R+ EP
Sbjct: 8 LLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEP 67
Query: 71 RTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDN 130
R PW++ ++ W + +Q L+GW MF V+ + ++NHS SHT Q ++GCE+ ED
Sbjct: 68 RAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSG-SHTYQRMIGCELLEDG 126
Query: 131 STEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQ 190
ST G+ +Y YDGQD L F DTL W A + A K WE ++ + +LE +C A
Sbjct: 127 STTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAW 186
Query: 191 LQQLLELGRGVLDQQVPPLVKVTHHVT-SSVTTLRCRALNYYPQNITMKWLKDKQPMDAK 249
L++ LE G+ L + PPLV+V T VT L C+A +YP I M W+K+ + + +
Sbjct: 187 LKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEI-VQ 245
Query: 250 EFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGV 309
E + D+LP+GDGTYQ W ++ + P Y+C VEH G+ L V E S + LV+
Sbjct: 246 EIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQE-SETIPLVMKA 304
Query: 310 ISGIAVFVVILFIGILFIILRKR 332
+SG V V++L G+ ++ R+R
Sbjct: 305 VSGSIVLVIVL-AGVGVLVWRRR 326
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 216 bits (551), Expect = 2e-56
Identities = 125/345 (36%), Positives = 187/345 (54%), Gaps = 9/345 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
P LLL+L L SHS+ Y F S G F A+GYVDD FV +D +
Sbjct: 6 PRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAA 65
Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
S+R+EPR PW+ + W Q ++++K VD T+ +N S+ SHT+Q++ G
Sbjct: 66 SQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG 124
Query: 124 CEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C++ D GY + YDG+D++ D W AA+ A TK +WE A Q RAY
Sbjct: 125 CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAAH-EAEQLRAY 183
Query: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
L+ C L++ LE G+ L + PP +THH ++ TLRC AL +YP IT+ W +
Sbjct: 184 LDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL + WE S
Sbjct: 244 DGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSS 302
Query: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLA 345
T+ ++G+I+G+ + ++ ++ ++ +R+ S G Y A
Sbjct: 303 QPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQA 347
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 215 bits (548), Expect = 4e-56
Identities = 123/342 (35%), Positives = 185/342 (54%), Gaps = 9/342 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE-- 64
P +LL+L L SHS+ Y + S G F ++GYVDD FV +D +
Sbjct: 6 PRTVLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAA 65
Query: 65 SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
S R EPR PW+ + W + +Q K + +N S+ SHTLQ + G
Sbjct: 66 SPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG 124
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C++ D G+ +Y YDG+D++ D W AA+ A T+ +WE + A Q RAY
Sbjct: 125 CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAAR-EAEQRRAY 183
Query: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
LE +C L++ LE G+ L++ PP VTHH ++ TLRC AL +YP IT+ W +
Sbjct: 184 LEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQR 243
Query: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
D + ++ E + P GD T+Q W + VP GEEQRYTC V+H GL +PL + WEPS
Sbjct: 244 DGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSS 302
Query: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 342
T+ ++G+++G+AV V++ ++ ++ +R+ S G G Y
Sbjct: 303 QSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSY 344
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 210 bits (534), Expect = 2e-54
Identities = 122/319 (38%), Positives = 177/319 (55%), Gaps = 9/319 (2%)
Query: 27 SHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMW 84
SHSL Y + S LG F ++GYVDD FV +D +S R EPR PW+ + W
Sbjct: 39 SHSLRYFYTAVSRPGLGEPRFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYW 97
Query: 85 LQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDG 142
+ ++ +K F V T+ +N S+ SHTLQ++ GC++ D G+ + YDG
Sbjct: 98 DEQTRIVKDTAQSFRVGLNTLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDG 157
Query: 143 QDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVL 202
+D++ D W AA+ A TK + E RQ R YLE C L++ LE G+ L
Sbjct: 158 RDYIALNEDLRSWTAADTAAQITKRKREAAGAAERQ-RNYLEGRCVEGLRRYLETGKDAL 216
Query: 203 DQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGD 261
+ PP VTHH ++ TLRC AL +YP+ I++ W ++ + ++ E + P+GD
Sbjct: 217 LRADPPKAHVTHHPISEREVTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGD 275
Query: 262 GTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILF 321
GT+Q W L VP GEEQRYTC+V+H GL +PL + WEP + L++G+I G+ + VV L
Sbjct: 276 GTFQKWAALVVPSGEEQRYTCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALV 335
Query: 322 IGILFIILRKRQGSRGAMG 340
G + I +KR G G G
Sbjct: 336 AGAV-IWRKKRSGREGREG 353
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 206 bits (524), Expect = 2e-53
Identities = 129/346 (37%), Positives = 183/346 (52%), Gaps = 13/346 (3%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
M PRA LLL+L L SHS+ Y S G F ++GYVDD FV
Sbjct: 4 MAPRA----LLLLLSGGLALTETWACSHSMRYFDTAVSRPGRGEPRFISVGYVDDTQFVR 59
Query: 61 YDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHT 117
+D + S R EPR PWV + W + +Q K V + +N S++ SHT
Sbjct: 60 FDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSEDGSHT 118
Query: 118 LQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRA 176
LQ + GC++ D GY + YDG+D++ D W AA+ A T+ + E + A
Sbjct: 119 LQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAARA-A 177
Query: 177 RQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSS-VTTLRCRALNYYPQNI 235
Q RAYLE C L++ LE G+ L + PP VTHH S TLRC AL +YP I
Sbjct: 178 EQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGFYPAEI 237
Query: 236 TMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIV 295
T+ W +D + ++ E + P GDGT+Q W + VP G+EQRYTC ++H GL +PL +
Sbjct: 238 TLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTL 296
Query: 296 IWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 340
WEPS T+ ++G+++G+AV VV+ +G + + R+ S G G
Sbjct: 297 SWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKG 342
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 203 bits (517), Expect = 2e-52
Identities = 120/335 (35%), Positives = 179/335 (53%), Gaps = 9/335 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P L L+L L SHS+ Y S G F A+GYVDD FV +D +S
Sbjct: 6 PRTLFLLLSGALTLTETWAGSHSMRYFSAAVSRPGRGEPRFIAMGYVDDTQFVRFDSDSA 65
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK-ESHTLQVILG 123
R+EPR PWV + W + +++ K ++ T+ +N S+ SHTLQ ++G
Sbjct: 66 CPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQTLRGYYNQSEASSHTLQWMIG 124
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C++ D GY +Y YDG+D+L D W AA+ A +K + E + A Q RAY
Sbjct: 125 CDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANV-AEQRRAY 183
Query: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
LE C L + LE G+ +L + PP VTHH V TLRC AL +YP I + W +
Sbjct: 184 LEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYEATLRCWALGFYPAEIILTWQR 243
Query: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
D + ++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +PL++ W+ S
Sbjct: 244 DGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWKQSS 302
Query: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 335
T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 303 LPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 202 bits (515), Expect = 3e-52
Identities = 121/342 (35%), Positives = 180/342 (52%), Gaps = 9/342 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
Query: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
LE +C L++ LE G+ L + PP V HH ++ TLRC AL +YP IT+ W +
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
Query: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 342
T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 202 bits (515), Expect = 3e-52
Identities = 121/342 (35%), Positives = 180/342 (52%), Gaps = 9/342 (2%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
Query: 124 CEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
Query: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLK 241
LE +C L++ LE G+ L + PP V HH ++ TLRC AL +YP IT+ W +
Sbjct: 181 LEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLTWQR 240
Query: 242 DKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSP 301
D + ++ E + P GDGT+Q W + VPPGEEQRYTC V+H GL QPLI+ WE SP
Sbjct: 241 DGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSP 299
Query: 302 SGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHY 342
T+ ++G+++G+ V ++ ++ ++ +++ S G Y
Sbjct: 300 QPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSY 341
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 201 bits (512), Expect = 6e-52
Identities = 120/343 (34%), Positives = 184/343 (53%), Gaps = 9/343 (2%)
Query: 10 LLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHE--SRR 67
LLL+L + L SHSL Y S G F ++GYVDD FV +D++ S R
Sbjct: 6 LLLLLSEALALTQTWAGSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPR 65
Query: 68 VEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILGCEM 126
+ PR PW+ S+ W + ++S + +F V+ T+ +N S+ SHTLQ + GCE+
Sbjct: 66 MVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGCEL 124
Query: 127 QEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLER 185
D GY ++ YDG+D+L D W A + A ++ + A RAYLE
Sbjct: 125 GPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQK-SNDASEAEHQRAYLED 183
Query: 186 DCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSVTTLRCRALNYYPQNITMKWLKDKQ 244
C L + LE G+ L PP VTHH ++ TLRC AL +YP IT+ W +D +
Sbjct: 184 TCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQQDGE 243
Query: 245 PMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGT 304
++ E + P GDGT+Q W + VP GEEQRYTC V+H GL +P+ + W+P+ T
Sbjct: 244 G-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWKPASQPT 302
Query: 305 L-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAE 346
+ ++G+I+G+ + ++ ++ ++ +++ S G G Y AE
Sbjct: 303 IPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKGGSYSKAE 345
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 198 bits (503), Expect = 7e-51
Identities = 113/302 (37%), Positives = 167/302 (55%), Gaps = 11/302 (3%)
Query: 4 RARPALL-LLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYD 62
R P LL LL+LL AV Q +SL Y++ G S+ + F+ALG ++D F Y+
Sbjct: 3 RMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSKHVEDVPAFQALGSLNDLQFFRYN 62
Query: 63 HESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVIL 122
+ R+ +P W + W Q SQ K + +F I+E +N S SH LQ
Sbjct: 63 SKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYYNDSNGSHVLQGRF 121
Query: 123 GCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
GCE++ + S+ +WKY YDG+D++EF + W +P A TK +WE + ++ +AY
Sbjct: 122 GCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKWEAEPVYVQRAKAY 181
Query: 183 LERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLK 241
LE +CPA L++ L+ + +LD+Q PP V VT H L+C A ++YP I + W +
Sbjct: 182 LEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAYDFYPGKIDVHWTR 241
Query: 242 DKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE 298
+ EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+H L QPL+V WE
Sbjct: 242 AGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWE 296
Query: 299 PS 300
S
Sbjct: 297 AS 298
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 140 bits (354), Expect = 1e-33
Identities = 92/290 (31%), Positives = 147/290 (50%), Gaps = 23/290 (7%)
Query: 28 HSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQL 87
HSL Y M S+ S F A G++D Q F+ YD + RR +P+ W + + ++ W
Sbjct: 26 HSLRYNLMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTE 85
Query: 88 SQSLKGWDHMFTVDFWTIMENHNHSKES----HTLQVILGCEMQEDNSTEGYWKYGYDGQ 143
++ L T + + H K+ H+LQ I CE+ ED+ST G + YDG+
Sbjct: 86 TEDL-------TENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGE 138
Query: 144 ----DHLEFCPDTLDWRA-AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELG 198
+LE T+ + A+ A W+ ++ + + ++ DC +LQ+ L+ G
Sbjct: 139 LFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSG 198
Query: 199 RGVLDQQVPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVL 257
+ + VPP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVL
Sbjct: 199 VAIR-RTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVL 257
Query: 258 PNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 307
P+G+GTYQ W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 258 PDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 134 bits (338), Expect = 9e-32
Identities = 97/331 (29%), Positives = 152/331 (45%), Gaps = 25/331 (7%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL + G HSL Y S S F ++D Q F+ D +
Sbjct: 5 PVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKC 64
Query: 67 RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEM 126
R +P+ W + ++ W + ++ L G + T+ + + H+LQ I CE+
Sbjct: 65 RAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRM---TLAHIKDQKEGLHSLQEIRVCEI 121
Query: 127 QEDNSTEGYWKYGYDGQDHLEFCPDTLDWRA-----AEPRAWPTKLEWERHKIRARQNRA 181
EDNST + YDG+ L +T +W A+ A + + ++ + +
Sbjct: 122 HEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYH 181
Query: 182 YLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT-TLRCRALNYYPQNITMKWL 240
+ DC +L++ L+ G VL + VPP+V VT S T+ CRA +YP NIT+ W
Sbjct: 182 AMHADCLQELRRYLKSGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR 240
Query: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300
+D + + DVLP+G+GTYQ W+ + GEEQR+TC +EH G P
Sbjct: 241 QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHST-----HPV 295
Query: 301 PSG----------TLVIGVISGIAVFVVILF 321
PSG T + ++ A+FV+I+F
Sbjct: 296 PSGKVLVLQSHWQTFHVSAVAAAAIFVIIIF 326
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 127 bits (318), Expect = 2e-29
Identities = 94/327 (28%), Positives = 152/327 (46%), Gaps = 15/327 (4%)
Query: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Y+ EP WV S W + + L+ + +F F + K +TLQ
Sbjct: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
+LGCE+ DN++ K+ +G++ + F W P A W++ A +
Sbjct: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALNYYPQNITMKW 239
+L CP +L++ LE GRG L+ + PP +++ +S + L C A ++YP + +++
Sbjct: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
Query: 240 LKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE- 298
L++ + D PN DG++ +L V G+E Y C V+H GL QPL V E
Sbjct: 236 LRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
Query: 299 PSPSGTLVIGVISGIAVFVVILFIGIL 325
P+ S LV+G++ G+ + G L
Sbjct: 293 PAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 127 bits (318), Expect = 2e-29
Identities = 94/327 (28%), Positives = 152/327 (46%), Gaps = 15/327 (4%)
Query: 3 PRARPALLLLMLLQTAVLQGRL-LRSH-SLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
PR +P L L+L +L G L SH SL Y S G F G++ Q ++
Sbjct: 4 PRPQPWALGLLLF---LLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS 60
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Y+ EP WV S W + + L+ + +F F + K +TLQ
Sbjct: 61 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL-----GGKGPYTLQG 115
Query: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
+LGCE+ DN++ K+ +G++ + F W P A W++ A +
Sbjct: 116 LLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKEL 175
Query: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALNYYPQNITMKW 239
+L CP +L++ LE GRG L+ + PP +++ +S + L C A ++YP + +++
Sbjct: 176 TFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRF 235
Query: 240 LKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE- 298
L++ + D PN DG++ +L V G+E Y C V+H GL QPL V E
Sbjct: 236 LRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELES 292
Query: 299 PSPSGTLVIGVISGIAVFVVILFIGIL 325
P+ S LV+G++ G+ + G L
Sbjct: 293 PAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
sapiens]
Length = 76
Score = 99.0 bits (245), Expect = 6e-21
Identities = 50/51 (98%), Positives = 51/51 (100%)
Query: 298 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
+PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76
Score = 51.6 bits (122), Expect = 1e-06
Identities = 29/53 (54%), Positives = 37/53 (69%), Gaps = 3/53 (5%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYV 53
MGPRARPALLLLMLLQTAVLQGRLL+ L +G G+++F + ++
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLQPSPSGTLVIGVIS---GIAVFVVILFI 50
>gi|149158700 major histocompatibility complex, class I, F isoform 3
precursor [Homo sapiens]
Length = 254
Score = 92.8 bits (229), Expect = 4e-19
Identities = 70/221 (31%), Positives = 102/221 (46%), Gaps = 9/221 (4%)
Query: 7 PALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESR 66
P LLL+L L SHSL Y S G + A+ YVDD F+ +D ++
Sbjct: 3 PRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDSDAA 62
Query: 67 --RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKE-SHTLQVILG 123
R+EPR PWV Q W + K V ++ +N S+ SHTLQ + G
Sbjct: 63 IPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQGMNG 121
Query: 124 CEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAY 182
C+M D GY ++ YDG+D++ D W AA+ A T+ +E + A + R Y
Sbjct: 122 CDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEY-AEEFRTY 180
Query: 183 LERDCPAQLQQLLELGRGVL---DQQVPPLVKVTHHVTSSV 220
LE +C L++ LE G+ L +Q P + + V V
Sbjct: 181 LEGECLELLRRYLENGKETLQRAEQSPQPTIPIVGIVAGLV 221
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 88.2 bits (217), Expect = 1e-17
Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 12/218 (5%)
Query: 130 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 186
N TE G +Y Y+ +++ F D +RA P P W K + RA L+
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110
Query: 187 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 243
C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 244 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 303
Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S
Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225
Query: 304 TLVIGVISGIAVFVV-ILFIGILFIILRKRQGSRGAMG 340
+ ++SGI FV+ ++F+G+ II + Q G
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG 263
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 88.2 bits (217), Expect = 1e-17
Identities = 77/289 (26%), Positives = 127/289 (43%), Gaps = 30/289 (10%)
Query: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTL-- 118
+ ++S V PW S Q W L + + FT D + E + S+ L
Sbjct: 58 WSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRD---VKEFAKMLRLSYPLEL 114
Query: 119 QVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--------EWE 170
QV GCE+ N++ ++ + G+D L F W + L +W
Sbjct: 115 QVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQVLNQDKWT 172
Query: 171 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRAL 228
R ++ N CP + LLE G+ L +QV P ++ + L C
Sbjct: 173 RETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227
Query: 229 NYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPG 288
+YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C+V+H
Sbjct: 228 GFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
Query: 289 LD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 335
L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 286 LEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 87.8 bits (216), Expect = 1e-17
Identities = 65/211 (30%), Positives = 102/211 (48%), Gaps = 12/211 (5%)
Query: 130 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 186
N TE G +Y Y+ +++ F D +RA P P W K + RA L+
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110
Query: 187 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 243
C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 244 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 303
Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S
Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225
Query: 304 TLVIGVISGIAVFVV-ILFIGILFIILRKRQ 333
+ ++SGI FV+ ++F+G+ II + Q
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQ 256
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 85.5 bits (210), Expect = 6e-17
Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 9/201 (4%)
Query: 137 KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 196
+Y Y+ +++ F D +RA P+ P W K RA L+ C +
Sbjct: 61 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF- 119
Query: 197 LGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEP 253
RG+L ++V P V ++ T ++ L C ++YP I ++W ++ Q A
Sbjct: 120 --RGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVST 177
Query: 254 KDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGI 313
++ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SG+
Sbjct: 178 P-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGV 235
Query: 314 AVFVV-ILFIGILFIILRKRQ 333
FV+ ++F+G+ II ++ Q
Sbjct: 236 GGFVLGLIFLGLGLIIRQRSQ 256
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 85.1 bits (209), Expect = 8e-17
Identities = 64/211 (30%), Positives = 101/211 (47%), Gaps = 12/211 (5%)
Query: 130 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 186
N TE G +Y Y+ +++ F D +RA P P W K + RA ++
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTV 110
Query: 187 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 243
C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 244 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 303
Q A ++ NGD T+Q + L + P YTC VEHP L P+ V W + S
Sbjct: 168 QEETAGVVSTP-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSE 225
Query: 304 TLVIGVISGIAVFVV-ILFIGILFIILRKRQ 333
+ ++SGI FV+ ++F+G+ II + Q
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQ 256
>gi|239748788 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 2 [Homo sapiens]
Length = 281
Score = 81.3 bits (199), Expect = 1e-15
Identities = 60/205 (29%), Positives = 97/205 (47%), Gaps = 9/205 (4%)
Query: 140 YDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGR 199
Y+ ++ + F D ++RA P W K + RA ++R C Q LEL R
Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-R 120
Query: 200 GVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDV 256
L ++V P V ++ T ++ L C ++YP I ++W ++ Q A +
Sbjct: 121 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-L 179
Query: 257 LPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVF 316
+ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SGI F
Sbjct: 180 IRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGF 238
Query: 317 VV-ILFIGILFIILRKRQGSRGAMG 340
V+ ++F+G+ II + Q G
Sbjct: 239 VLGLIFLGLGLIIHHRSQKGEEPQG 263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,422,979
Number of Sequences: 37866
Number of extensions: 675967
Number of successful extensions: 1850
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1606
Number of HSP's gapped (non-prelim): 152
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.