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Search of human proteins with 4503433
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503433 E2F transcription factor 3 [Homo sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503433 E2F transcription factor 3 [Homo sapiens] 915 0.0
gi|4758226 E2F transcription factor 2 [Homo sapiens] 321 1e-87
gi|12669911 E2F transcription factor 1 [Homo sapiens] 278 8e-75
gi|109637795 E2F transcription factor 6 [Homo sapiens] 187 2e-47
gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens] 158 1e-38
gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens] 157 2e-38
gi|12669915 E2F transcription factor 4 [Homo sapiens] 155 6e-38
gi|134142813 E2F transcription factor 5 isoform 3 [Homo sapiens] 60 3e-09
gi|38505226 E2F family member 8 [Homo sapiens] 60 3e-09
gi|145580626 E2F transcription factor 7 [Homo sapiens] 54 2e-07
gi|116734702 homeobox D13 [Homo sapiens] 47 4e-05
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 43 5e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 41 0.002
gi|22538470 eomesodermin [Homo sapiens] 41 0.003
gi|6005900 transcription factor Dp-1 [Homo sapiens] 40 0.003
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 40 0.003
gi|4557595 forkhead box F2 [Homo sapiens] 40 0.004
gi|19111150 angiomotin isoform 2 [Homo sapiens] 40 0.006
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 40 0.006
gi|166064029 angiomotin isoform 1 [Homo sapiens] 40 0.006
gi|153218470 BarH-like homeobox 1 [Homo sapiens] 40 0.006
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens] 40 0.006
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 39 0.010
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 39 0.013
gi|239752280 PREDICTED: similar to family with sequence similari... 38 0.017
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 38 0.017
gi|210032463 family with sequence similarity 48, member B2 [Homo... 38 0.017
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 38 0.017
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens] 38 0.022
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens] 38 0.022
>gi|4503433 E2F transcription factor 3 [Homo sapiens]
Length = 465
Score = 915 bits (2364), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQI 60
MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQI
Sbjct: 1 MRKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQI 60
Query: 61 LTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG 120
LTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG
Sbjct: 61 LTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG 120
Query: 121 RGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYD 180
RGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYD
Sbjct: 121 RGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYD 180
Query: 181 TSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQ 240
TSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQ
Sbjct: 181 TSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQ 240
Query: 241 WMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVT 300
WMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVT
Sbjct: 241 WMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVT 300
Query: 301 YQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSP 360
YQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSP
Sbjct: 301 YQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESLQIHLASTQGPIEVYLCPEETETHSP 360
Query: 361 MKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEG 420
MKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEG
Sbjct: 361 MKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEG 420
Query: 421 PFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS 465
PFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
Sbjct: 421 PFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS 465
>gi|4758226 E2F transcription factor 2 [Homo sapiens]
Length = 437
Score = 321 bits (822), Expect = 1e-87
Identities = 213/445 (47%), Positives = 255/445 (57%), Gaps = 50/445 (11%)
Query: 45 AAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA--GPLLPSAPGAEQTAGSLLYTT 102
A A+AA P + T + SS A A PL P G+ L T
Sbjct: 7 ALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPGTCLDAT 66
Query: 103 PHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALR 162
PHGP + +++ PA G PAKR+L+L G + + TPKGK
Sbjct: 67 PHGPEGQ--VVRCLPA---------GRLPAKRKLDLEGIGRPVVPE-FPTPKGKCIRVDG 114
Query: 163 SPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDIT 222
P SPKTPKSP EKTRYDTSLGLLTKKFI LLS+S DGVLDLN AAEVL VQKRRIYDIT
Sbjct: 115 LP-SPKTPKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDIT 173
Query: 223 NVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTL 282
NVLEGI LI+KK+KNN+QW+G + ED + Q L +E+ EL E+ LD+LIQSC+L
Sbjct: 174 NVLEGIQLIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSL 233
Query: 283 DLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLAS 341
K LTED N+RLAYVTYQDIR + K+QTVI VKAPP+TRLEVPD E +LQI+L S
Sbjct: 234 SFKHLTEDKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKS 293
Query: 342 TQGPIEVYLCPEET-ETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPL 400
TQGPIEVYLCPEE E SP + + P P S +S+ +D S+ S +
Sbjct: 294 TQGPIEVYLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSS----TDPSIMEPTASSV 349
Query: 401 ASPA--------------------------NLLQQTEDQIPS---NLEGPFVNLLPPLLQ 431
+PA LLQQTEDQ S P ++ P L Q
Sbjct: 350 PAPAPTPQQAPPPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQ 409
Query: 432 EDYLLSLGEEEGISDLFDAYDLEKL 456
+DYL L EGISDLFD+YDL L
Sbjct: 410 DDYLWGLEAGEGISDLFDSYDLGDL 434
>gi|12669911 E2F transcription factor 1 [Homo sapiens]
Length = 437
Score = 278 bits (711), Expect = 8e-75
Identities = 183/444 (41%), Positives = 245/444 (55%), Gaps = 50/444 (11%)
Query: 37 ALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAG 96
AL +P A A A + ++S S+ Q + P P+AP A
Sbjct: 2 ALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDP 61
Query: 97 SLL-YTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKG 155
LL + TP P + PALGR PP KRRL+L E+ HQYL++ +G
Sbjct: 62 DLLLFATPQAPRPTPSAPR--PALGR--------PPVKRRLDL-ETDHQYLAESSGPARG 110
Query: 156 KGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQK 215
+GR K KSP EK+RY+TSL L TK+F++LLS S DGV+DLN AAEVLKVQK
Sbjct: 111 RGR------HPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQK 164
Query: 216 RRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDE 275
RRIYDITNVLEGI LI KKSKN++QW+G + G+ + +GL++++ +L + E++LD
Sbjct: 165 RRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTV--GVGGRLEGLTQDLRQLQESEQQLDH 222
Query: 276 LIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIESL 335
L+ CT L+LL+ED+++QRLAYVT QD+R I+ +Q V+V+KAPPET+L+ DS E+
Sbjct: 223 LMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENF 282
Query: 336 QIHLASTQGPIEVYLCPEETETH-SPMKTNNQDHNGN------------IPKPASKDLAS 382
QI L S QGPI+V+LCPEET SP KT +Q+ P P+S +
Sbjct: 283 QISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSL 342
Query: 383 TNS-----------------GHSDCSVSMGNLSPLASPANLLQQTEDQIPSNLEGPFVNL 425
T G V LSPL + +LL+ + L F++L
Sbjct: 343 TTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISL 402
Query: 426 LPPLLQEDYLLSLGEEEGISDLFD 449
PP DY L E EGI DLFD
Sbjct: 403 SPPHEALDYHFGLEEGEGIRDLFD 426
>gi|109637795 E2F transcription factor 6 [Homo sapiens]
Length = 281
Score = 187 bits (474), Expect = 2e-47
Identities = 97/181 (53%), Positives = 130/181 (71%), Gaps = 2/181 (1%)
Query: 175 EKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKK 234
++ R+D SL LT+KF+ L+ +P G+LDLNK A L V+KRR+YDITNVL+GI L++KK
Sbjct: 60 KRPRFDVSLVYLTRKFMDLVRSAPGGILDLNKVATKLGVRKRRVYDITNVLDGIDLVEKK 119
Query: 235 SKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQ 294
SKN+++W+G LS + G + Q + L +E+++LS E LDELI+ C L LT+D EN+
Sbjct: 120 SKNHIRWIGSDLS-NFGAVPQQKKLQEELSDLSAMEDALDELIKDCAQQLFELTDDKENE 178
Query: 295 RLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVPDSIE-SLQIHLASTQGPIEVYLCPE 353
RLAYVTYQDI I +Q VI VKAP ETRL+VP E S+ +H+ ST GPI+VYLC
Sbjct: 179 RLAYVTYQDIHSIQAFHEQIVIAVKAPAETRLDVPAPREDSITVHIRSTNGPIDVYLCEV 238
Query: 354 E 354
E
Sbjct: 239 E 239
>gi|134142809 E2F transcription factor 5 isoform 2 [Homo sapiens]
Length = 345
Score = 158 bits (399), Expect = 1e-38
Identities = 115/338 (34%), Positives = 179/338 (52%), Gaps = 41/338 (12%)
Query: 147 SDGLKTPKGKGRAALRSPDSPKT----PKSPSE-------KTRYDTSLGLLTKKFIQLLS 195
S G + P G+G+ P P+ P P + +R++ SLGLLT KF+ LL
Sbjct: 8 SSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQ 67
Query: 196 QSPDGVLDLNKAAEVLKV-QKRRIYDITNVLEGIHLIKKKSKNNVQW----MGCSLSEDG 250
++ DGVLDL AA+ L V QKRRIYDITNVLEGI LI+KKSKN++QW GC+ E
Sbjct: 68 EAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKE-- 125
Query: 251 GMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGL 310
++ + + L E+ +L +E++LD+ +K + +DS N R +YVT++DI +
Sbjct: 126 -VIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDI--CNCF 182
Query: 311 KDQTVIVVKAPPETRLEVP------DSIESLQIHLASTQGPIEVYLCPEETETHSPMKTN 364
T++ ++AP T+LEVP + + QI+L S GPI V L +E+ + P+
Sbjct: 183 NGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFP 242
Query: 365 NQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTE--DQIPSNLEGPF 422
+ ++ +P+S+ L S + ++ + LQQT D ++ G
Sbjct: 243 VPPPD-DLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSGSISGDI 301
Query: 423 VNLLP-----PLLQ------EDYLLSLGEEEGISDLFD 449
++ L PLL+ +DY +L + EG+ DLFD
Sbjct: 302 IDELMSSDVFPLLRLSPTPADDYNFNLDDNEGVCDLFD 339
>gi|134142811 E2F transcription factor 5 isoform 1 [Homo sapiens]
Length = 346
Score = 157 bits (397), Expect = 2e-38
Identities = 114/340 (33%), Positives = 177/340 (52%), Gaps = 44/340 (12%)
Query: 147 SDGLKTPKGKGRAALRSPDSPKT----PKSPSE-------KTRYDTSLGLLTKKFIQLLS 195
S G + P G+G+ P P+ P P + +R++ SLGLLT KF+ LL
Sbjct: 8 SSGQQAPAGQGQGQRPPPQPPQAQAPQPPPPPQLGGAGGGSSRHEKSLGLLTTKFVSLLQ 67
Query: 196 QSPDGVLDLNKAAEVLKV-QKRRIYDITNVLEGIHLIKKKSKNNVQW----MGCSLSEDG 250
++ DGVLDL AA+ L V QKRRIYDITNVLEGI LI+KKSKN++QW GC+ E
Sbjct: 68 EAKDGVLDLKAAADTLAVRQKRRIYDITNVLEGIDLIEKKSKNSIQWKGVGAGCNTKE-- 125
Query: 251 GMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTEDSENQRLAYVTYQDIRKISGL 310
++ + + L E+ +L +E++LD+ +K + +DS N R +YVT++DI +
Sbjct: 126 -VIDRLRYLKAEIEDLELKERELDQQKLWLQQSIKNVMDDSINNRFSYVTHEDI--CNCF 182
Query: 311 KDQTVIVVKAPPETRLEVP------DSIESLQIHLASTQGPIEVYLCPEETETHSPMKTN 364
T++ ++AP T+LEVP + + QI+L S GPI V L +E+ + P+
Sbjct: 183 NGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSHSGPIHVLLINKESSSSKPVVFP 242
Query: 365 NQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTE------------- 411
+ ++ +P+S+ L S + ++ + LQQT
Sbjct: 243 VPPPD-DLTQPSSQSLTPVTPQKSSMATQNLPEQHVSERSQALQQTSATDISSAGSISGD 301
Query: 412 --DQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFD 449
D++ S+ P + L P +DY +L + EG+ DLFD
Sbjct: 302 IIDELMSSDVFPLLR-LSPTPADDYNFNLDDNEGVCDLFD 340
>gi|12669915 E2F transcription factor 4 [Homo sapiens]
Length = 413
Score = 155 bits (393), Expect = 6e-38
Identities = 105/261 (40%), Positives = 145/261 (55%), Gaps = 32/261 (12%)
Query: 167 PKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKV-QKRRIYDITNVL 225
P+ P P +R++ SLGLLT KF+ LL ++ DGVLDL AA+ L V QKRRIYDITNVL
Sbjct: 6 PQAPPPPGTPSRHEKSLGLLTTKFVSLLQEAKDGVLDLKLAADTLAVRQKRRIYDITNVL 65
Query: 226 EGIHLIKKKSKNNVQWM----GCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCT 281
EGI LI+KKSKN++QW GC+ E L + L E+ EL Q E++LD+
Sbjct: 66 EGIGLIEKKSKNSIQWKGVGPGCNTREIADKLIE---LKAEIEELQQREQELDQHKVWVQ 122
Query: 282 LDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVP-----DSIESLQ 336
++ +TED +N LAYVT++DI + T++ ++AP T LEVP + + Q
Sbjct: 123 QSIRNVTEDVQNSCLAYVTHEDICRC--FAGDTLLAIRAPSGTSLEVPIPEGLNGQKKYQ 180
Query: 337 IHLASTQGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGN 396
IHL S GPIEV L +E + P+ +P P +DL + S ++
Sbjct: 181 IHLKSVSGPIEVLLVNKEAWSSPPVA---------VPVPPPEDLLQSPS-------AVST 224
Query: 397 LSPLASPANLLQQTEDQIPSN 417
PL PA L Q E P++
Sbjct: 225 PPPLPKPA-LAQSQEASRPNS 244
Score = 38.1 bits (87), Expect = 0.017
Identities = 21/95 (22%), Positives = 42/95 (44%)
Query: 355 TETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLASPANLLQQTEDQI 414
+ + S +N+ +G P + + + + +G + + + + E+ +
Sbjct: 313 SSSSSSSNSNSSSSSGPNPSTSFEPIKADPTGVLELPKELSEIFDPTRECMSSELLEELM 372
Query: 415 PSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFD 449
S + P + L PP DY+ +L E EG+ DLFD
Sbjct: 373 SSEVFAPLLRLSPPPGDHDYIYNLDESEGVCDLFD 407
>gi|134142813 E2F transcription factor 5 isoform 3 [Homo sapiens]
Length = 185
Score = 60.5 bits (145), Expect = 3e-09
Identities = 50/182 (27%), Positives = 85/182 (46%), Gaps = 25/182 (13%)
Query: 289 EDSENQRLAYVTYQDIRKISGLKDQTVIVVKAPPETRLEVP------DSIESLQIHLAST 342
+DS N R +YVT++DI + T++ ++AP T+LEVP + + QI+L S
Sbjct: 2 DDSINNRFSYVTHEDI--CNCFNGDTLLAIQAPSGTQLEVPIPEMGQNGQKKYQINLKSH 59
Query: 343 QGPIEVYLCPEETETHSPMKTNNQDHNGNIPKPASKDLASTNSGHSDCSVSMGNLSPLAS 402
GPI V L +E+ + P+ + ++ +P+S+ L S + ++
Sbjct: 60 SGPIHVLLINKESSSSKPVVFPVPPPD-DLTQPSSQSLTPVTPQKSSMATQNLPEQHVSE 118
Query: 403 PANLLQQTE---------------DQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDL 447
+ LQQT D++ S+ P + L P +DY +L + EG+ DL
Sbjct: 119 RSQALQQTSATDISSAGSISGDIIDELMSSDVFPLLRL-SPTPADDYNFNLDDNEGVCDL 177
Query: 448 FD 449
FD
Sbjct: 178 FD 179
>gi|38505226 E2F family member 8 [Homo sapiens]
Length = 867
Score = 60.5 bits (145), Expect = 3e-09
Identities = 36/104 (34%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 174 SEKTRYDTSLGLLTKKFIQLLSQSPDGVLD----LNKAAEVLKVQKRRIYDITNVLEGIH 229
S+ +R + SLGLL KF+ P+ ++ L++ AE L V++RRIYDI NVLE +H
Sbjct: 109 SQPSRKEKSLGLLCHKFLARYPNYPNPAVNNDICLDEVAEELNVERRRIYDIVNVLESLH 168
Query: 230 LIKKKSKNNVQWMG-CSLSEDGGMLAQCQGLSKEVTELSQEEKK 272
++ + +KN W G +L++ G L +K ++ +KK
Sbjct: 169 MVSRLAKNRYTWHGRHNLNKTLGTLKSIGEENKYAEQIMMIKKK 212
Score = 43.1 bits (100), Expect = 5e-04
Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 14/77 (18%)
Query: 171 KSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVL--------------KVQKR 216
++ S +R D SL ++++KF+ L S ++ L AA++L K + R
Sbjct: 254 RAASVNSRKDKSLRVMSQKFVMLFLVSTPQIVSLEVAAKILIGEDHVEDLDKSKFKTKIR 313
Query: 217 RIYDITNVLEGIHLIKK 233
R+YDI NVL + LIKK
Sbjct: 314 RLYDIANVLSSLDLIKK 330
>gi|145580626 E2F transcription factor 7 [Homo sapiens]
Length = 911
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/71 (40%), Positives = 41/71 (57%), Gaps = 4/71 (5%)
Query: 177 TRYDTSLGLLTKKFIQLLSQSP----DGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIK 232
+R SLGLL +KF+ P + L++ A L V++RRIYDI NVLE +HL+
Sbjct: 141 SRKQKSLGLLCQKFLARYPSYPLSTEKTTISLDEVAVSLGVERRRIYDIVNVLESLHLVS 200
Query: 233 KKSKNNVQWMG 243
+ +KN W G
Sbjct: 201 RVAKNQYGWHG 211
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/83 (36%), Positives = 44/83 (53%), Gaps = 17/83 (20%)
Query: 164 PDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVL------------ 211
PD P S S +R D SL ++++KF+ L S ++ L+ AA++L
Sbjct: 272 PDCP----SSSANSRKDKSLRIMSQKFVMLFLVSKTKIVTLDVAAKILIEESQDAPDHSK 327
Query: 212 -KVQKRRIYDITNVLEGIHLIKK 233
K + RR+YDI NVL + LIKK
Sbjct: 328 FKTKVRRLYDIANVLTSLALIKK 350
>gi|116734702 homeobox D13 [Homo sapiens]
Length = 343
Score = 47.0 bits (110), Expect = 4e-05
Identities = 48/129 (37%), Positives = 56/129 (43%), Gaps = 27/129 (20%)
Query: 17 GGGEGAAVVA------AAAAASMDKRALLASPGFA-----------AAAAAAAAPGAYIQ 59
GGG G A + AAAAAS R L++P FA AAAAAAAA +
Sbjct: 16 GGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFA 75
Query: 60 ILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPAL 119
T+ T S SSS S VAA P P P E A + P++ A PAL
Sbjct: 76 YPGTSERTGSSSSSSSSAVVAARPEAP--PAKECPAPT--------PAAAAAAPPSAPAL 125
Query: 120 GRGGSGGGG 128
G G G G
Sbjct: 126 GYGYHFGNG 134
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 43.1 bits (100), Expect = 5e-04
Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 24/88 (27%)
Query: 43 GFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAG-SLLYT 101
G+ AAAAAAAA + A AA LPS G +Q SLLY+
Sbjct: 186 GWGAAAAAAAA----------------------AAAAAAAAHLPSMAGGQQPPPQSLLYS 223
Query: 102 TPHGPSSRAGLLQQPPALGRGGSGGGGG 129
P G + G+L PP G GG G GGG
Sbjct: 224 QPGGFTVN-GMLSAPPGPGGGGGGAGGG 250
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
[Homo sapiens]
Length = 3969
Score = 41.2 bits (95), Expect = 0.002
Identities = 47/177 (26%), Positives = 65/177 (36%), Gaps = 24/177 (13%)
Query: 15 TAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSL 74
T GGG G A ALL PG AP + + + S + +
Sbjct: 15 TTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGV 74
Query: 75 QSGAVAAGPLLPSAPGAEQTAGSLLYTTPH----GPSSRAGLLQQPPALGR--------- 121
GA AA S+ + ++ S + P GP A LQ A+G
Sbjct: 75 PGGAAAASAASSSSASSSSSSSSSASSGPALLRVGPGFDAA-LQVSAAIGTNLRRFRAVF 133
Query: 122 GGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTR 178
G SGGGGG GE Q+L G + + R+ RSP +P+ P + R
Sbjct: 134 GESGGGGGS--------GED-EQFLGFG-SDEEVRVRSPTRSPSVKTSPRKPRGRPR 180
>gi|22538470 eomesodermin [Homo sapiens]
Length = 686
Score = 40.8 bits (94), Expect = 0.003
Identities = 52/154 (33%), Positives = 60/154 (38%), Gaps = 37/154 (24%)
Query: 2 RKGIQPALEQYLVTAGGGEGAAVVAAAAAA--SMD----KRALLASPGFAAAAAAAAAPG 55
RKG P E+ L +A AA AAAA A SMD +R L SPG + AA
Sbjct: 104 RKG-SPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSSERYYLQSPGPQGSELAAP--- 159
Query: 56 AYIQILTTNTSTTSCSSSLQSGAVAA--GPLLPSAPGAEQTAGSLLYTTPHGPSSRA--- 110
CS A A GP+ P+ GA GS+L P G A
Sbjct: 160 --------------CSLFPYQAAAGAPHGPVYPAPNGARYPYGSML---PPGGFPAAVCP 202
Query: 111 -GLLQQPPALGRG----GSGGGGGPPAKRRLELG 139
G Q P G G GS GGGG P + G
Sbjct: 203 PGRAQFGPGAGAGSGAGGSSGGGGGPGTYQYSQG 236
>gi|6005900 transcription factor Dp-1 [Homo sapiens]
Length = 410
Score = 40.4 bits (93), Expect = 0.003
Identities = 47/207 (22%), Positives = 82/207 (39%), Gaps = 36/207 (17%)
Query: 75 QSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKR 134
QS A ++ P + +L+ +PH PS+ QP +G +
Sbjct: 53 QSNVNIAQQVVIGTPQRPAASNTLVVGSPHTPSTHFASQNQPSDSSPWSAG--------K 104
Query: 135 RLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLL 194
R GE GKG K + + TS + + +
Sbjct: 105 RNRKGEKN------------GKGLRHFSMKVCEKVQRKGT------TSYNEVADELVAEF 146
Query: 195 SQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLA 254
S + + +L N++A K +RR+YD NVL +++I K+ K ++W+G +
Sbjct: 147 SAADNHILP-NESAYDQKNIRRRVYDALNVLMAMNIISKE-KKEIKWIGLPTNS----AQ 200
Query: 255 QCQGLSKE----VTELSQEEKKLDELI 277
+CQ L E + + Q++ +L ELI
Sbjct: 201 ECQNLEVERQRRLERIKQKQSQLQELI 227
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 40.4 bits (93), Expect = 0.003
Identities = 46/165 (27%), Positives = 60/165 (36%), Gaps = 22/165 (13%)
Query: 31 ASMDKRALLASPGFAAAAAAAAAPGAYIQILT-----TNTSTTSCSSSLQSGAVAAGPLL 85
A R+ L G A + + P A +++ + S +S SS S + A P
Sbjct: 234 AHCQSRSDLLKAGGGAGGSGGSGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGG 293
Query: 86 PSAPGAEQTAGSLLYTTPHGPSS---RAGLLQQP------------PALGRGGSGGGGGP 130
P PG T S+ YT PS AGL A G GG GGGGG
Sbjct: 294 PGGPGFASTDISM-YTLSRDPSKGSVAAGLAGAGGGGGGAVGAFGGAAGGAGGGGGGGGG 352
Query: 131 PAKRRLELGESGHQYLSDGLKTPKGKG-RAALRSPDSPKTPKSPS 174
R G SG L + G G + P +P P P+
Sbjct: 353 AGAERDRGGASGFLTLHNAFPKEAGGGVTVTVTGPPAPPAPAPPA 397
>gi|4557595 forkhead box F2 [Homo sapiens]
Length = 444
Score = 40.0 bits (92), Expect = 0.004
Identities = 30/85 (35%), Positives = 42/85 (49%)
Query: 13 LVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSS 72
+ T GG A + A + +A L SP AAAAAAAAAP ++++++ + SS
Sbjct: 1 MTTEGGPPPAPLRRACSPVPGALQAALMSPPPAAAAAAAAAPETTSSSSSSSSASCASSS 60
Query: 73 SLQSGAVAAGPLLPSAPGAEQTAGS 97
S + A A SA G AGS
Sbjct: 61 SSSNSASAPSAACKSAGGGGAGAGS 85
>gi|19111150 angiomotin isoform 2 [Homo sapiens]
Length = 675
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/96 (30%), Positives = 41/96 (42%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA 81
AA A AAA+ A SP AAA AAA +P A QI + ++ + + + A AA
Sbjct: 500 AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAA 559
Query: 82 GPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPP 117
+ P+AP + P + A Q P
Sbjct: 560 VQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAP 595
Score = 30.8 bits (68), Expect = 2.7
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 16/98 (16%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAA----AAAAAPGAYIQILTTNTSTTSCSSSLQSG 77
A V AAA AA++ A + AAA AAAAAP A + + S +
Sbjct: 476 APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAA------------AAAPSPATA 523
Query: 78 AVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQ 115
A A + P+A G A S+ PS+ A Q
Sbjct: 524 AATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQ 561
Score = 29.3 bits (64), Expect = 7.9
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA 81
AA V+ AAA + A +AS AAA A +AA A +Q+ + + + A AA
Sbjct: 527 AAAVSPAAAGQIPAAASVAS---AAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAA 583
Query: 82 GPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSG 125
A T+ + TP + A + PA G G
Sbjct: 584 AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPG 627
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 39.7 bits (91), Expect = 0.006
Identities = 34/154 (22%), Positives = 69/154 (44%), Gaps = 3/154 (1%)
Query: 19 GEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGA 78
G+G ++ RA ASP +++++++++ + ++++S++S SSS S +
Sbjct: 2591 GDGGCGTGGRNCSAASSRA--ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 79 VAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLEL 138
++ S+ + ++ S +T SS + + PA G P K +
Sbjct: 2649 SSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPA-PTAGPSAQAALPTKATKQA 2707
Query: 139 GESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKS 172
G++ S G KTP + +A P P PK+
Sbjct: 2708 GKARPSAHSPGKKTPAPQPQAPPPQPTQPLQPKA 2741
Score = 35.4 bits (80), Expect = 0.11
Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 11/146 (7%)
Query: 26 AAAAAASMDKRALLASPG--FAAAAAAAAAPGAYIQILTTNTSTTSCSSSL--QSGAVA- 80
AA AAS K+A L PG +AA P A + + S SL SG+ A
Sbjct: 539 AAVVAASSSKKAYL-DPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFAR 597
Query: 81 -AGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGR-GGSGGGGGPPAKRRLEL 138
A + P G + G L P + AG + L GG GGG KR E
Sbjct: 598 DAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPER 657
Query: 139 GESGHQYLSDGLKTPKGKGRAALRSP 164
ES + G + +G A +R P
Sbjct: 658 PESAKAF---GREGSGAQGEAEVRHP 680
>gi|166064029 angiomotin isoform 1 [Homo sapiens]
Length = 1084
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/96 (30%), Positives = 41/96 (42%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA 81
AA A AAA+ A SP AAA AAA +P A QI + ++ + + + A AA
Sbjct: 909 AAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAA 968
Query: 82 GPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPP 117
+ P+AP + P + A Q P
Sbjct: 969 VQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQAP 1004
Score = 30.8 bits (68), Expect = 2.7
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 16/98 (16%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAA----AAAAAPGAYIQILTTNTSTTSCSSSLQSG 77
A V AAA AA++ A + AAA AAAAAP A + + S +
Sbjct: 885 APVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAA------------AAAPSPATA 932
Query: 78 AVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQ 115
A A + P+A G A S+ PS+ A Q
Sbjct: 933 AATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQ 970
Score = 29.3 bits (64), Expect = 7.9
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 3/104 (2%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA 81
AA V+ AAA + A +AS AAA A +AA A +Q+ + + + A AA
Sbjct: 936 AAAVSPAAAGQIPAAASVAS---AAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAA 992
Query: 82 GPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSG 125
A T+ + TP + A + PA G G
Sbjct: 993 AQASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPG 1036
>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
Length = 254
Score = 39.7 bits (91), Expect = 0.006
Identities = 39/112 (34%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 9 LEQYLVTAGGGEGAAVVAAAAAAS----MDKRALLASPGFAAAAAAAAAPGAYIQILTTN 64
+E+ L G +GAA AAAAAA +ALLA+ F + A A A +
Sbjct: 31 IEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQA--AVFKFP 88
Query: 65 TSTTSCSSSLQSGAVAAGPLLPSAPGAE------QTAGSLLYTTPHGPSSRA 110
+ CS L S +AAGP LP A GA Q G L P P ++A
Sbjct: 89 LAPLGCSG-LSSALLAAGPGLPGAAGAPHLPLELQLRGKLEAAGPGEPGTKA 139
>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
Length = 887
Score = 39.7 bits (91), Expect = 0.006
Identities = 34/99 (34%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA 81
AA +AAAAAA+ A A+ A A AAAAAP L + +++ + A AA
Sbjct: 496 AAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPA-----LAAAAAPALAAAAAPAPAPAA 550
Query: 82 GPLLPSAPGAEQTAGSLLYTTPHGP---SSRAGLLQQPP 117
P + +AP A +A P P +SR QPP
Sbjct: 551 APAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPP 589
Score = 32.0 bits (71), Expect = 1.2
Identities = 25/90 (27%), Positives = 36/90 (40%)
Query: 30 AASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPLLPSAP 89
A S KR A+ AAAAAAAAA A + + ++ + A A +AP
Sbjct: 485 AGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAP 544
Query: 90 GAEQTAGSLLYTTPHGPSSRAGLLQQPPAL 119
A + P +S A Q P++
Sbjct: 545 APAPAAAPAVAAAPAAAASAAPSHSQKPSV 574
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 38.9 bits (89), Expect = 0.010
Identities = 43/123 (34%), Positives = 49/123 (39%), Gaps = 39/123 (31%)
Query: 7 PALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTS 66
P L Q A G AA AAAAAA+ AAAA++AAA GA + S
Sbjct: 341 PGLYQAPAAAAGLNSAASAAAAAAAA------------AAAASSAAAAGAPPSGGSAPCS 388
Query: 67 TTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGG 126
SC SS + A AA A +L SR G G GG GG
Sbjct: 389 CLSCHSSQSAAAAAAA-----------AAAAL--------GSRGG--------GGGGGGG 421
Query: 127 GGG 129
GGG
Sbjct: 422 GGG 424
Score = 36.2 bits (82), Expect = 0.065
Identities = 36/128 (28%), Positives = 50/128 (39%), Gaps = 12/128 (9%)
Query: 14 VTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAA---------AAAAAPGAYIQILTTN 64
VTA AA AAAAA+S ++ F A + + PG Y
Sbjct: 292 VTAAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAA 351
Query: 65 TSTTSCSSSLQSGAVAAGPLLPSAPGAEQTAGSL---LYTTPHGPSSRAGLLQQPPALGR 121
++ S++ + A AA +A GA + GS + S+ A ALG
Sbjct: 352 GLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGS 411
Query: 122 GGSGGGGG 129
G GGGGG
Sbjct: 412 RGGGGGGG 419
Score = 31.6 bits (70), Expect = 1.6
Identities = 35/125 (28%), Positives = 47/125 (37%), Gaps = 25/125 (20%)
Query: 18 GGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSG 77
G E ++AA K+ PG + AAA A + +++ CS+ G
Sbjct: 83 GSESTVSSEISSAAESRKK-----PGHYSEAAAEADMSSDVEV--------GCSALRSPG 129
Query: 78 AVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPAKRRLE 137
+ A L + +GS TT S G L GGSGG GG A
Sbjct: 130 GLGAAQLKENNGKGYAESGSAAGTTTSASGSGLGSLH-------GGSGGSGGSAA----- 177
Query: 138 LGESG 142
LG SG
Sbjct: 178 LGGSG 182
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 38.5 bits (88), Expect = 0.013
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 40/181 (22%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAY--IQILTTNTSTTSCSS------S 73
AA A+AAAAS LL G A A AA A+ +L +T+ + +S S
Sbjct: 240 AAAAASAAAAS----GLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNS 295
Query: 74 LQSG---AVAAGPLLPSAPGAEQTAGSLL-----YTTPHGPSSRAGLLQQPP----ALGR 121
L G A A+G L A GA A + Y G G PP ALG
Sbjct: 296 LGLGLNSAAASGVLAAVAAGANPAAAAAANLLASYAGEAGAGPAGGAAPPPPPPPGALGS 355
Query: 122 ----------------GGSGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPD 165
GG+GGGGGP G +G ++ L K + P+
Sbjct: 356 FALAAAANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPE 415
Query: 166 S 166
+
Sbjct: 416 N 416
>gi|239752280 PREDICTED: similar to family with sequence similarity
48, member B2 [Homo sapiens]
Length = 779
Score = 38.1 bits (87), Expect = 0.017
Identities = 53/179 (29%), Positives = 66/179 (36%), Gaps = 17/179 (9%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA 81
AA A AAAA A A+P AAAA AAAA GA + +S + A
Sbjct: 457 AAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRP 516
Query: 82 GPLLPSAPGAEQTAGS--LLYTTPHGPSSRAGLL------------QQPPALGRGGSG-- 125
+ AP + GS L T GP A +L P G GSG
Sbjct: 517 TRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQ 576
Query: 126 GGGGP-PAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSL 183
GGP P R + S L L TP+G L+ P P +++ SL
Sbjct: 577 SSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSL 635
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 38.1 bits (87), Expect = 0.017
Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 3/130 (2%)
Query: 2 RKGIQPALEQYLVTAGGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQIL 61
+K P E + G V+++A++S + A+P AAAA P A L
Sbjct: 109 KKKSSPVRESSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL 168
Query: 62 TTNTSTTSCS-SSLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALG 120
+T +++ S +S+ G+ A +P A + + G ++ A P + G
Sbjct: 169 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAA--SYPMSYG 226
Query: 121 RGGSGGGGGP 130
+GGS G G P
Sbjct: 227 QGGSYGQGYP 236
>gi|210032463 family with sequence similarity 48, member B2 [Homo
sapiens]
Length = 817
Score = 38.1 bits (87), Expect = 0.017
Identities = 53/179 (29%), Positives = 66/179 (36%), Gaps = 17/179 (9%)
Query: 22 AAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA 81
AA A AAAA A A+P AAAA AAAA GA + +S + A
Sbjct: 495 AAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRP 554
Query: 82 GPLLPSAPGAEQTAGS--LLYTTPHGPSSRAGLL------------QQPPALGRGGSG-- 125
+ AP + GS L T GP A +L P G GSG
Sbjct: 555 TRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQ 614
Query: 126 GGGGP-PAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSL 183
GGP P R + S L L TP+G L+ P P +++ SL
Sbjct: 615 SSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSL 673
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
sapiens]
Length = 2161
Score = 38.1 bits (87), Expect = 0.017
Identities = 34/122 (27%), Positives = 49/122 (40%), Gaps = 8/122 (6%)
Query: 19 GEGAAVVAAAAAASMDKRALL------ASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSS 72
G G V A A+ D L ++PG A++ A G+ Q + +T S
Sbjct: 425 GTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSG 484
Query: 73 SLQSGAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPA 132
+L+S + G S + P G S +G ++ PA G GGSGG GG
Sbjct: 485 TLRSASSPRGARARSPSRGRHPEDAK--RQPRGRPSSSGTPREGPAGGTGGSGGPGGSLG 542
Query: 133 KR 134
R
Sbjct: 543 SR 544
Score = 31.2 bits (69), Expect = 2.1
Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 24/108 (22%)
Query: 49 AAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAA-------GPLLPSAP------------ 89
A AAAP ++ TS S ++L GA AA GP P+AP
Sbjct: 1609 AVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPP 1668
Query: 90 -----GAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPA 132
G E+ P S A L A G G +GGGGG A
Sbjct: 1669 PGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGA 1716
>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
Length = 508
Score = 37.7 bits (86), Expect = 0.022
Identities = 39/116 (33%), Positives = 46/116 (39%), Gaps = 28/116 (24%)
Query: 17 GGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQS 76
GG AA AAAAAA+ A L S F + +PG+ LT SSS +
Sbjct: 81 GGSSSAAAAAAAAAAA---AAALVSDSF----SCGGSPGSSAFSLT--------SSSAAA 125
Query: 77 GAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPA 132
A AA S+P A Y+ P G G GG GGGGG A
Sbjct: 126 AAAAAAAAASSSPFAND------YSVFQAPGVSGG-------SGGGGGGGGGGSSA 168
Score = 35.0 bits (79), Expect = 0.14
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 25 VAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPL 84
V ++ +S + G ++AAAAAAA A L ++ + SC S S A +
Sbjct: 64 VVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSD--SFSCGGSPGSSAFS---- 117
Query: 85 LPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGG 129
L S+ A A + + ++ + Q P G G GGGGG
Sbjct: 118 LTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGG 162
>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
Length = 490
Score = 37.7 bits (86), Expect = 0.022
Identities = 39/116 (33%), Positives = 46/116 (39%), Gaps = 28/116 (24%)
Query: 17 GGGEGAAVVAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQS 76
GG AA AAAAAA+ A L S F + +PG+ LT SSS +
Sbjct: 63 GGSSSAAAAAAAAAAA---AAALVSDSF----SCGGSPGSSAFSLT--------SSSAAA 107
Query: 77 GAVAAGPLLPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGGPPA 132
A AA S+P A Y+ P G G GG GGGGG A
Sbjct: 108 AAAAAAAAASSSPFAND------YSVFQAPGVSGG-------SGGGGGGGGGGSSA 150
Score = 35.0 bits (79), Expect = 0.14
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 25 VAAAAAASMDKRALLASPGFAAAAAAAAAPGAYIQILTTNTSTTSCSSSLQSGAVAAGPL 84
V ++ +S + G ++AAAAAAA A L ++ + SC S S A +
Sbjct: 46 VVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSD--SFSCGGSPGSSAFS---- 99
Query: 85 LPSAPGAEQTAGSLLYTTPHGPSSRAGLLQQPPALGRGGSGGGGG 129
L S+ A A + + ++ + Q P G G GGGGG
Sbjct: 100 LTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGG 144
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,080,317
Number of Sequences: 37866
Number of extensions: 1079080
Number of successful extensions: 8647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 330
Number of HSP's that attempted gapping in prelim test: 6661
Number of HSP's gapped (non-prelim): 1810
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.