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Search of human proteins with 4502649
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502649 CD1D antigen precursor [Homo sapiens]
(335 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502649 CD1D antigen precursor [Homo sapiens] 697 0.0
gi|110618240 CD1E antigen isoform a precursor [Homo sapiens] 363 e-100
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens] 359 2e-99
gi|110618224 CD1A antigen precursor [Homo sapiens] 341 6e-94
gi|4502645 CD1B antigen precursor [Homo sapiens] 338 4e-93
gi|110618227 CD1C antigen precursor [Homo sapiens] 325 3e-89
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens] 286 2e-77
gi|110618234 CD1E antigen isoform d precursor [Homo sapiens] 247 1e-65
gi|110618236 CD1E antigen isoform e precursor [Homo sapiens] 195 5e-50
gi|110618238 CD1E antigen isoform f precursor [Homo sapiens] 122 6e-28
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 88 9e-18
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 88 9e-18
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 84 2e-16
gi|4504417 major histocompatibility complex, class I-related [Ho... 84 2e-16
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 79 6e-15
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 78 1e-14
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 76 4e-14
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 76 4e-14
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 76 5e-14
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 75 1e-13
gi|52630342 major histocompatibility complex, class I, C precurs... 73 3e-13
gi|17986001 major histocompatibility complex, class I, B precurs... 73 4e-13
gi|24797067 major histocompatibility complex, class I, A precurs... 69 5e-12
gi|149158702 major histocompatibility complex, class I, F isofor... 68 1e-11
gi|149158698 major histocompatibility complex, class I, F isofor... 68 1e-11
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 65 7e-11
gi|4504415 major histocompatibility complex, class I, G precurso... 64 1e-10
gi|62912479 major histocompatibility complex, class I, E precurs... 62 7e-10
gi|34335272 endothelial protein C receptor precursor [Homo sapiens] 57 2e-08
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 57 3e-08
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 697 bits (1798), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSN 60
MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSN
Sbjct: 1 MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSN 60
Query: 61 DSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGC 120
DSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGC
Sbjct: 61 DSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGC 120
Query: 121 EVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLL 180
EVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLL
Sbjct: 121 EVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLL 180
Query: 181 NGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMR 240
NGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMR
Sbjct: 181 NGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMR 240
Query: 241 GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYT 300
GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYT
Sbjct: 241 GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYT 300
Query: 301 SMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335
SMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL
Sbjct: 301 SMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335
>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
Length = 388
Score = 363 bits (932), Expect = e-100
Identities = 185/342 (54%), Positives = 234/342 (68%), Gaps = 15/342 (4%)
Query: 4 LLFLLLWALLQAWGSAEVPQRL----------FPLRCLQISSFANSSWTRTDGLAWLGEL 53
LLFLL L + PQ L R LQ SSFAN SW ++G WLG+L
Sbjct: 3 LLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDL 62
Query: 54 QTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLE 113
QTH W T+R LKPWS G FS Q+ + LQ +F++Y SF + V+ A +L YP E
Sbjct: 63 QTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFE 122
Query: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTR 173
+Q+ AGC + NA F ++A+QG D LSFQG SWEP+ A + +VLN+ +
Sbjct: 123 IQILAGCRM---NAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIK 179
Query: 174 ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKP 233
E +Q LL TCP+F++GL+E+G+SELK++VKP+AWLS GPSPGPGRL LVCHVSGFYPKP
Sbjct: 180 EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKP 239
Query: 234 VWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVL 293
VWV WMRGEQEQ+GTQ GD+LPNADETWYLRATLDV AGEAAGLSCRVKHSSL G D+++
Sbjct: 240 VWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLII 299
Query: 294 YWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335
+WGG + LI L V+ L+ L++V SR K+Q+S + +L
Sbjct: 300 HWGGYSIFLILICLTVIVTLVILVVV--DSRLKKQSSNKNIL 339
>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
Length = 376
Score = 359 bits (922), Expect = 2e-99
Identities = 183/336 (54%), Positives = 230/336 (68%), Gaps = 15/336 (4%)
Query: 4 LLFLLLWALLQAWGSAEVPQRL----------FPLRCLQISSFANSSWTRTDGLAWLGEL 53
LLFLL L + PQ L R LQ SSFAN SW ++G WLG+L
Sbjct: 3 LLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDL 62
Query: 54 QTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLE 113
QTH W T+R LKPWS G FS Q+ + LQ +F++Y SF + V+ A +L YP E
Sbjct: 63 QTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFE 122
Query: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTR 173
+Q+ AGC + NA F ++A+QG D LSFQG SWEP+ A + +VLN+ +
Sbjct: 123 IQILAGCRM---NAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIK 179
Query: 174 ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKP 233
E +Q LL TCP+F++GL+E+G+SELK++VKP+AWLS GPSPGPGRL LVCHVSGFYPKP
Sbjct: 180 EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKP 239
Query: 234 VWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVL 293
VWV WMRGEQEQ+GTQ GD+LPNADETWYLRATLDV AGEAAGLSCRVKHSSL G D+++
Sbjct: 240 VWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLII 299
Query: 294 YWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQT 329
+WGG + LI L V+ L+ L++V SR K+Q+
Sbjct: 300 HWGGYSIFLILICLTVIVTLVILVVV--DSRLKKQS 333
>gi|110618224 CD1A antigen precursor [Homo sapiens]
Length = 327
Score = 341 bits (874), Expect = 6e-94
Identities = 170/327 (51%), Positives = 225/327 (68%), Gaps = 5/327 (1%)
Query: 4 LLFLLL--WALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSND 61
+LFLLL A+L G+A+ + I+SF N SW + WL +LQTH+W ++
Sbjct: 1 MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN 60
Query: 62 SDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCE 121
S T+ L PWS+G FS+++W+ L+ +FR+ ++ +A L+ YP E+QV+ GCE
Sbjct: 61 SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE 120
Query: 122 VHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLN 181
+H G S +F +A+QG D +SFQ SW P A +VLNQ++ + LL+
Sbjct: 121 LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS 180
Query: 182 GTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRG 241
TCP+F+ GLL++GK+ L++QVKP+AWLS GPSPGPG L LVCHVSGFYPKPVWV WMRG
Sbjct: 181 DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG 240
Query: 242 EQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTS 301
EQEQQGTQ GDILP+AD TWYLRATL+V AGEAA LSCRVKHSSLEGQDIVLYW ++S
Sbjct: 241 EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYW-EHHSS 299
Query: 302 MGLIALAVLACLLFLLIVGFTSRFKRQ 328
+G I LAV+ L LL++G F+++
Sbjct: 300 VGFIILAVIVPL--LLLIGLALWFRKR 324
>gi|4502645 CD1B antigen precursor [Homo sapiens]
Length = 333
Score = 338 bits (867), Expect = 4e-93
Identities = 176/331 (53%), Positives = 218/331 (65%), Gaps = 2/331 (0%)
Query: 4 LLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSD 63
L F LL L S Q +Q SSF NS+W +T G WL +LQ H W +DS
Sbjct: 4 LPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSG 63
Query: 64 TVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVH 123
T LKPWS+G FSD++ L+ IFRVY F R+V++FA ++ YP E+Q AGCE+H
Sbjct: 64 TAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCELH 123
Query: 124 PGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGT 183
G A +F A G D LS + S P+ E ++ Q + ETV+ LL T
Sbjct: 124 SGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILLYET 183
Query: 184 CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQ 243
CP+++ G+L +GK++L++QVKP+AWLS GPSPGPGRL LVCHVSGFYPKPVWV WMRGEQ
Sbjct: 184 CPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ 243
Query: 244 EQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMG 303
EQQGTQ GDILPNA+ TWYLRATLDV GEAAGLSCRVKHSSLEGQDI+LYW TS+G
Sbjct: 244 EQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNP-TSIG 302
Query: 304 LIALAVLACLLFLLIVGFTSRFKRQTSYQGV 334
I LA++ L LL+ + R+ SYQ +
Sbjct: 303 SIVLAIIVPSLLLLLC-LALWYMRRRSYQNI 332
>gi|110618227 CD1C antigen precursor [Homo sapiens]
Length = 333
Score = 325 bits (833), Expect = 3e-89
Identities = 166/333 (49%), Positives = 214/333 (64%), Gaps = 4/333 (1%)
Query: 4 LLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSD 63
L FLLL LL +A+ Q +QI SF N SW R G WL ELQTH W ++S
Sbjct: 4 LQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDSESG 63
Query: 64 TVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVH 123
T+ L WS+G FS+++ L+ +FR Y TR++++ A YP E+QV AGCE+H
Sbjct: 64 TIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGCELH 123
Query: 124 PGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLN-QDKWTRETVQWLLNG 182
G + FF VAF G D+LSFQ T+W P+ +LN Q + ETV L+
Sbjct: 124 SGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNHQYEGVTETVYNLIRS 183
Query: 183 TCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGE 242
TCP+F+ GLL++GK + +QV+P+AWLS PS G G+LLLVCH SGFYPKPVWV WMR E
Sbjct: 184 TCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNE 243
Query: 243 QEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSM 302
QEQ GT+ GDILPNAD TWYL+ L+V + E AGLSCRV+HSSL GQDI+LYWG + SM
Sbjct: 244 QEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHHF-SM 302
Query: 303 GLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL 335
IAL V+ L+ L+++ FK+ SYQ +L
Sbjct: 303 NWIALVVIVPLVILIVL--VLWFKKHCSYQDIL 333
>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
Length = 290
Score = 286 bits (732), Expect = 2e-77
Identities = 143/270 (52%), Positives = 181/270 (67%), Gaps = 13/270 (4%)
Query: 4 LLFLLLWALLQAWGSAEVPQRL----------FPLRCLQISSFANSSWTRTDGLAWLGEL 53
LLFLL L + PQ L R LQ SSFAN SW ++G WLG+L
Sbjct: 3 LLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDL 62
Query: 54 QTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLE 113
QTH W T+R LKPWS G FS Q+ + LQ +F++Y SF + V+ A +L YP E
Sbjct: 63 QTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFE 122
Query: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTR 173
+Q+ AGC + NA F ++A+QG D LSFQG SWEP+ A + +VLN+ +
Sbjct: 123 IQILAGCRM---NAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIK 179
Query: 174 ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKP 233
E +Q LL TCP+F++GL+E+G+SELK++VKP+AWLS GPSPGPGRL LVCHVSGFYPKP
Sbjct: 180 EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKP 239
Query: 234 VWVKWMRGEQEQQGTQPGDILPNADETWYL 263
VWV WMRGEQEQ+GTQ GD+LPNADETW++
Sbjct: 240 VWVMWMRGEQEQRGTQRGDVLPNADETWWI 269
>gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]
Length = 321
Score = 247 bits (630), Expect = 1e-65
Identities = 126/248 (50%), Positives = 160/248 (64%), Gaps = 13/248 (5%)
Query: 4 LLFLLLWALLQAWGSAEVPQRL----------FPLRCLQISSFANSSWTRTDGLAWLGEL 53
LLFLL L + PQ L R LQ SSFAN SW ++G WLG+L
Sbjct: 3 LLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGDL 62
Query: 54 QTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLE 113
QTH W T+R LKPWS G FS Q+ + LQ +F++Y SF + V+ A +L YP E
Sbjct: 63 QTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPFE 122
Query: 114 LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTR 173
+Q+ AGC + NA F ++A+QG D LSFQG SWEP+ A + +VLN+ +
Sbjct: 123 IQILAGCRM---NAPQIFLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDIK 179
Query: 174 ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKP 233
E +Q LL TCP+F++GL+E+G+SELK++VKP+AWLS GPSPGPGRL LVCHVSGFYPKP
Sbjct: 180 EILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKP 239
Query: 234 VWVKWMRG 241
VWV WMRG
Sbjct: 240 VWVMWMRG 247
>gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
Length = 187
Score = 195 bits (495), Expect = 5e-50
Identities = 92/127 (72%), Positives = 106/127 (83%), Gaps = 2/127 (1%)
Query: 203 VKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWY 262
VKP+AWLS GPSPGPGRL LVCHVSGFYPKPVWV WMRGEQEQ+GTQ GD+LPNADETWY
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
Query: 263 LRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFT 322
LRATLDV AGEAAGLSCRVKHSSL G D++++WGG + LI L V+ L+ L++V
Sbjct: 80 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVV--D 137
Query: 323 SRFKRQT 329
SR K+Q+
Sbjct: 138 SRLKKQS 144
>gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]
Length = 101
Score = 122 bits (305), Expect = 6e-28
Identities = 52/61 (85%), Positives = 57/61 (93%)
Query: 203 VKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWY 262
VKP+AWLS GPSPGPGRL LVCHVSGFYPKPVWV WMRGEQEQ+GTQ GD+LPNADETW+
Sbjct: 20 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 79
Query: 263 L 263
+
Sbjct: 80 I 80
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 88.2 bits (217), Expect = 9e-18
Identities = 77/289 (26%), Positives = 127/289 (43%), Gaps = 30/289 (10%)
Query: 58 WSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRD---VKEFAKMLRLSYPLEL 114
+ ++S V PW S Q W L + + FT D + E + S+ L
Sbjct: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTL-- 95
Query: 115 QVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQVLNQDKWT 172
QV GCE+ N++ ++ + G+D L F W + L +W
Sbjct: 96 QVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--------EWE 147
Query: 173 RETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227
R ++ N CP + LLE G+ L +QV P ++ + L C
Sbjct: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRAL 205
Query: 228 GFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
+YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C+V+H
Sbjct: 206 NYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPG 265
Query: 286 LEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 266 LD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 312
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 88.2 bits (217), Expect = 9e-18
Identities = 77/289 (26%), Positives = 127/289 (43%), Gaps = 30/289 (10%)
Query: 58 WSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRD---VKEFAKMLRLSYPLEL 114
+ ++S V PW S Q W L + + FT D + E + S+ L
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTL-- 118
Query: 115 QVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQVLNQDKWT 172
QV GCE+ N++ ++ + G+D L F W + L +W
Sbjct: 119 QVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--------EWE 170
Query: 173 RETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227
R ++ N CP + LLE G+ L +QV P ++ + L C
Sbjct: 171 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRAL 228
Query: 228 GFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
+YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C+V+H
Sbjct: 229 NYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPG 288
Query: 286 LEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 289 LD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 335
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 84.0 bits (206), Expect = 2e-16
Identities = 76/289 (26%), Positives = 123/289 (42%), Gaps = 44/289 (15%)
Query: 58 WSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRD---VKEFAKMLRLSYPLEL 114
+ ++S V PW S Q W L + + FT D + E + S+ L
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTL-- 118
Query: 115 QVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQVLNQDKWT 172
QV GCE+ N++ ++ + G+D L F W + L +W
Sbjct: 119 QVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--------EWE 170
Query: 173 RETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227
R ++ N CP + LLE G+ L +QV L C
Sbjct: 171 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT----------------LRCRAL 214
Query: 228 GFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
+YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C+V+H
Sbjct: 215 NYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPG 274
Query: 286 LEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 275 LD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 321
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 83.6 bits (205), Expect = 2e-16
Identities = 64/258 (24%), Positives = 107/258 (41%), Gaps = 20/258 (7%)
Query: 70 PWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASN 129
PW + WE + R ++ F ++K + S Q GCE+ ++
Sbjct: 70 PWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTT 129
Query: 130 NFFHVAFQGKDILSF--QGTSWEPTQEA-----PLWVNLAIQVLNQDKWTRETVQWLLNG 182
F A+ G+D L F SW W ++L Q W E
Sbjct: 130 GFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEE-------- 181
Query: 183 TCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMR-G 241
C ++ LE GK L++ P ++R PG L C GFYP +++ WM+ G
Sbjct: 182 ECIAWLKRFLEYGKDTLQRTEPPLVRVNR-KETFPGVTALFCKAHGFYPPEIYMTWMKNG 240
Query: 242 EQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTS 301
E+ Q GDILP+ D T+ A++++ + SC V+H G +VL +
Sbjct: 241 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHC---GVHMVLQVPQESET 297
Query: 302 MGLIALAVLACLLFLLIV 319
+ L+ AV ++ ++++
Sbjct: 298 IPLVMKAVSGSIVLVIVL 315
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 79.0 bits (193), Expect = 6e-15
Identities = 66/237 (27%), Positives = 108/237 (45%), Gaps = 25/237 (10%)
Query: 107 RLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQ 164
RL LQV GCE+ N++ ++ + G+D L F W + L
Sbjct: 23 RLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--- 79
Query: 165 VLNQDKWTRETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGR 219
+W R ++ N CP + LLE G+ L +QV P ++ +
Sbjct: 80 -----EWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTT 134
Query: 220 LLLVCHVSGFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGL 277
L C +YP+ + +KW++ +Q + P D+LPN D T+ TL V GE
Sbjct: 135 LR--CRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 192
Query: 278 SCRVKHSSLEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
+C+V+H L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 193 TCQVEHPGLD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 247
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 78.2 bits (191), Expect = 1e-14
Identities = 69/260 (26%), Positives = 109/260 (41%), Gaps = 19/260 (7%)
Query: 47 LAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKML 106
L L +LQ +++ + + W Q + W+ + + F +K+ +
Sbjct: 50 LGSLNDLQFFRYNSKDRKSQPMGLWRQ-VEGMEDWKQDSQLQKAREDIFMETLKDIVEYY 108
Query: 107 RLSYPLE-LQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNL--AI 163
S LQ GCE+ +S F+ + GKD + F +E P WV A
Sbjct: 109 NDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFN-------KEIPAWVPFDPAA 161
Query: 164 QVLNQDKWTRETV-----QWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPG 218
Q+ Q KW E V + L CP + L+ K+ L +Q P ++ +PG
Sbjct: 162 QITKQ-KWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEK 220
Query: 219 RLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLS 278
+ L C FYP + V W R + Q+ GD+L N + T+ + V + A S
Sbjct: 221 KKLK-CLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYS 279
Query: 279 CRVKHSSLEGQDIVLYWGGS 298
C V+HSSL Q +V+ W S
Sbjct: 280 CHVQHSSL-AQPLVVPWEAS 298
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 76.3 bits (186), Expect = 4e-14
Identities = 76/285 (26%), Positives = 120/285 (42%), Gaps = 13/285 (4%)
Query: 49 WLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRL 108
WLG Q S+++ W WE R+ F E K L
Sbjct: 52 WLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFL----EAFKALGG 107
Query: 109 SYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSF---QGTSWEPTQEAPLWVNLAIQV 165
P LQ GCE+ P N S A G++ ++F QGT W L ++ Q
Sbjct: 108 KGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGT-WGGDWPEALAISQRWQ- 165
Query: 166 LNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCH 225
QDK + + +LL +CP + LE G+ L+ + P L PS PG +L C
Sbjct: 166 -QQDKAANKELTFLLF-SCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCS 222
Query: 226 VSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
FYP + ++++R GT GD PN+D +++ ++L V +G+ C V+H+
Sbjct: 223 AFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG 281
Query: 286 LEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTS 330
L V + +S+ ++ + + LL VG ++R S
Sbjct: 282 LAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRS 326
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 76.3 bits (186), Expect = 4e-14
Identities = 76/285 (26%), Positives = 120/285 (42%), Gaps = 13/285 (4%)
Query: 49 WLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRL 108
WLG Q S+++ W WE R+ F E K L
Sbjct: 52 WLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFL----EAFKALGG 107
Query: 109 SYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSF---QGTSWEPTQEAPLWVNLAIQV 165
P LQ GCE+ P N S A G++ ++F QGT W L ++ Q
Sbjct: 108 KGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGT-WGGDWPEALAISQRWQ- 165
Query: 166 LNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCH 225
QDK + + +LL +CP + LE G+ L+ + P L PS PG +L C
Sbjct: 166 -QQDKAANKELTFLLF-SCPHRLREHLERGRGNLEWKEPPSMRLKARPS-SPGFSVLTCS 222
Query: 226 VSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
FYP + ++++R GT GD PN+D +++ ++L V +G+ C V+H+
Sbjct: 223 AFSFYPPELQLRFLRNGLAA-GTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG 281
Query: 286 LEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTS 330
L V + +S+ ++ + + LL VG ++R S
Sbjct: 282 LAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRS 326
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 75.9 bits (185), Expect = 5e-14
Identities = 62/225 (27%), Positives = 100/225 (44%), Gaps = 11/225 (4%)
Query: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
LQ+ GC+V P G F A+ G+D ++ SW A + +
Sbjct: 132 LQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTAAQITKRKREAAGAAE 191
Query: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230
R L G C + + LE+GK L + PKA ++ P + L C GFY
Sbjct: 192 RQRN----YLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPI-SEREVTLRCWALGFY 246
Query: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289
P+ + + W R GE + Q + + P+ D T+ A L V +GE +CRV+H L+ +
Sbjct: 247 PEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCRVQHEGLQ-E 305
Query: 290 DIVLYWGGSYTSMGLIALAV-LACLLFLLIVGFTSRFKRQTSYQG 333
+ L W TS ++ + V L L+ L+ G K+++ +G
Sbjct: 306 PLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAVIWRKKRSGREG 350
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 74.7 bits (182), Expect = 1e-13
Identities = 65/237 (27%), Positives = 104/237 (43%), Gaps = 39/237 (16%)
Query: 107 RLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQ 164
RL LQV GCE+ N++ ++ + G+D L F W + L
Sbjct: 23 RLLQSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--- 79
Query: 165 VLNQDKWTRETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGR 219
+W R ++ N CP + LLE G+ L +QV
Sbjct: 80 -----EWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVTT-------------- 120
Query: 220 LLLVCHVSGFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGL 277
L C +YP+ + +KW++ +Q + P D+LPN D T+ TL V GE
Sbjct: 121 --LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 178
Query: 278 SCRVKHSSLEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
+C+V+H L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 179 TCQVEHPGLD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 233
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 73.2 bits (178), Expect = 3e-13
Identities = 62/226 (27%), Positives = 101/226 (44%), Gaps = 15/226 (6%)
Query: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
LQ +GC++ P G + A+ GKD ++ SW A ++
Sbjct: 119 LQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTAAQITQRKLEAAR--- 175
Query: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230
E ++ L GTC +++ LE+GK L++ PK ++ P L C GFY
Sbjct: 176 -AAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPL-SDHEATLRCWALGFY 233
Query: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289
P + + W R GE + Q T+ + P D T+ A + V +G+ +C ++H L+ +
Sbjct: 234 PAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQ-E 292
Query: 290 DIVLYWGGS----YTSMGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
+ L W S MG++A LAVL L L V +R++S
Sbjct: 293 PLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSS 338
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 72.8 bits (177), Expect = 4e-13
Identities = 66/219 (30%), Positives = 98/219 (44%), Gaps = 23/219 (10%)
Query: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
LQ GC+V P G A+ GKD ++ SW A + Q K
Sbjct: 119 LQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQ--------ITQRK 170
Query: 171 W--TRETVQW--LLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHV 226
W RE Q L G C +++ LE+GK +L++ PK ++ P L C
Sbjct: 171 WEAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPI-SDHEATLRCWA 229
Query: 227 SGFYPKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
GFYP + + W R GE + Q T+ + P D T+ A + V +GE +C V+H
Sbjct: 230 LGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEG 289
Query: 286 LEGQDIVLYWGGSYTS----MGLIA-LAVLACLLFLLIV 319
L + + L W S S +G++A LAVLA ++ +V
Sbjct: 290 LP-KPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVV 327
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 69.3 bits (168), Expect = 5e-12
Identities = 58/216 (26%), Positives = 98/216 (45%), Gaps = 19/216 (8%)
Query: 114 LQVSAGCEV-HPGNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
+Q+ GC+V G + A+ GKD ++ SW ++A Q+ + K
Sbjct: 119 IQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAA-------DMAAQITKR-K 170
Query: 171 WTR----ETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHV 226
W E ++ L+GTC +++ LE+GK L++ PK ++ P L C
Sbjct: 171 WEAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPI-SDHEATLRCWA 229
Query: 227 SGFYPKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
GFYP + + W R GE + Q T+ + P D T+ A + V +GE +C V+H
Sbjct: 230 LGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEG 289
Query: 286 LEGQDIVLYWG-GSYTSMGLIALAVLACLLFLLIVG 320
L + + L W S ++ ++ + LL +I G
Sbjct: 290 LP-KPLTLRWELSSQPTIPIVGIIAGLVLLGAVITG 324
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 68.2 bits (165), Expect = 1e-11
Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 10/186 (5%)
Query: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
LQ GC++ P G + A+ GKD +S SW V Q + +
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADT----VAQITQRFYEAE 171
Query: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230
E + L G C + + LE+GK L++ PKA ++ P L C GFY
Sbjct: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
Query: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289
P + + W R GE++ Q T+ + P D T+ A + V GE +C V+H L Q
Sbjct: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
Query: 290 DIVLYW 295
++L W
Sbjct: 290 PLILRW 295
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 68.2 bits (165), Expect = 1e-11
Identities = 54/186 (29%), Positives = 81/186 (43%), Gaps = 10/186 (5%)
Query: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
LQ GC++ P G + A+ GKD +S SW V Q + +
Sbjct: 116 LQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADT----VAQITQRFYEAE 171
Query: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230
E + L G C + + LE+GK L++ PKA ++ P L C GFY
Sbjct: 172 EYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPI-SDHEATLRCWALGFY 230
Query: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289
P + + W R GE++ Q T+ + P D T+ A + V GE +C V+H L Q
Sbjct: 231 PAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLP-Q 289
Query: 290 DIVLYW 295
++L W
Sbjct: 290 PLILRW 295
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 65.5 bits (158), Expect = 7e-11
Identities = 69/285 (24%), Positives = 121/285 (42%), Gaps = 45/285 (15%)
Query: 71 WSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPL---------ELQVSAGCE 121
W++ ++ W+ TRD+ K LR++ LQ CE
Sbjct: 72 WAEDVLGNKTWDRE-----------TRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE 120
Query: 122 VHPGNASNNFFHVAFQGKDILS--FQGTSWEPTQEAPLWVNLAIQVLN---QDKWTRETV 176
+H N++ + H + G+ LS + W Q + LA+ V N +D +T
Sbjct: 121 IHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQT-LAMNVRNFLKEDAMKTKTH 179
Query: 177 QWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWV 236
++ C Q + L+SG L++ V P ++R + G + + C SGFYP + +
Sbjct: 180 YHAMHADCLQELRRYLKSGVV-LRRTVPPMVNVTRSEA-SEGNITVTCRASGFYPWNITL 237
Query: 237 KWMR-GEQEQQGTQP-GDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS-------LE 287
W + G TQ GD+LP+ + T+ + GE +C ++HS
Sbjct: 238 SWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPS 297
Query: 288 GQDIVL--YWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTS 330
G+ +VL +W + S AV A +F++I+ + K++TS
Sbjct: 298 GKVLVLQSHWQTFHVS------AVAAAAIFVIIIFYVRCCKKKTS 336
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 64.3 bits (155), Expect = 1e-10
Identities = 59/210 (28%), Positives = 91/210 (43%), Gaps = 15/210 (7%)
Query: 114 LQVSAGCEV-HPGNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQDK 170
LQ GC++ G + A+ GKD L+ SW A + N +
Sbjct: 119 LQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTAAQISKRKCEAANVAE 178
Query: 171 WTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFY 230
R L GTC +++ LE+GK L++ PK ++ P L C GFY
Sbjct: 179 QRRA----YLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHP-VFDYEATLRCWALGFY 233
Query: 231 PKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQ 289
P + + W R GE + Q + + P D T+ A + V +GE +C V+H L +
Sbjct: 234 PAEIILTWQRDGEDQTQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLP-E 292
Query: 290 DIVLYWGGS----YTSMGLIA-LAVLACLL 314
++L W S MG++A L VLA ++
Sbjct: 293 PLMLRWKQSSLPTIPIMGIVAGLVVLAAVV 322
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 62.0 bits (149), Expect = 7e-10
Identities = 55/189 (29%), Positives = 79/189 (41%), Gaps = 16/189 (8%)
Query: 114 LQVSAGCEVHP-GNASNNFFHVAFQGKDILSFQGT--SWEPTQEAPLWVNLAIQVLNQ-- 168
LQ GCE+ P G + A+ GKD L+ SW V+ A Q+ Q
Sbjct: 116 LQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTA-------VDTAAQISEQKS 168
Query: 169 -DKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227
D E + L TC +++ LE GK L PK ++ P L C
Sbjct: 169 NDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPI-SDHEATLRCWAL 227
Query: 228 GFYPKPVWVKWMR-GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSL 286
GFYP + + W + GE Q T+ + P D T+ A + V +GE +C V+H L
Sbjct: 228 GFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGL 287
Query: 287 EGQDIVLYW 295
+ + L W
Sbjct: 288 P-EPVTLRW 295
>gi|34335272 endothelial protein C receptor precursor [Homo sapiens]
Length = 238
Score = 57.0 bits (136), Expect = 2e-08
Identities = 57/193 (29%), Positives = 83/193 (43%), Gaps = 12/193 (6%)
Query: 4 LLFLLLWALLQAWG--SAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTH--SWS 59
L LL LL W S + L L LQIS F + G A LG TH
Sbjct: 2 LTTLLPILLLSGWAFCSQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGP 61
Query: 60 NDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAG 119
+ + T+ L+P + + W Q + Y F V+ + L++PL ++ G
Sbjct: 62 DTNTTIIQLQPLQE----PESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLG 117
Query: 120 CEVHP-GNASNNFFHVAFQGKDILSF--QGTSWE-PTQEAPLWVNLAIQVLNQDKWTRET 175
CE+ P G+ ++ FF VA G +SF + W+ TQ V +Q LN TR
Sbjct: 118 CELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYE 177
Query: 176 VQWLLNGTCPQFV 188
++ L TC Q+V
Sbjct: 178 LREFLEDTCVQYV 190
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 56.6 bits (135), Expect = 3e-08
Identities = 38/115 (33%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 222 LVCHVSGFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSC 279
L C +YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C
Sbjct: 43 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102
Query: 280 RVKHSSLEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
+V+H L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 103 QVEHPGLD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,482,252
Number of Sequences: 37866
Number of extensions: 704918
Number of successful extensions: 1733
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 1566
Number of HSP's gapped (non-prelim): 123
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.